Energy Technology Data Exchange (ETDEWEB)

A brief overview if provided of selected reports presented at the International Symposium on Molecular Mechanisms of Radiation- and Chemical Carcinogen-Induced Cell Transformation held at Mackinac Island, Michigan on September 19-23, 1993.

International Nuclear Information System (INIS)

This report briefly describes the studies on the mechanism of in vivo DNA repairing by the author in Research Reactor Institute, Kyoto Univ. for the past 30 years. First, the ability of UV radiation to induce transformation was investigated with viral DNA. The formation of thymine-thymine dimer was found harmful to organisms and such dimers were removable by UV-radiation at a low frequency. The mutability was determined in three different E.coli strains with mutator gene, mutT, mutS or mutL. The ability to excise 8-oxoguanin developed in primer DNA was deficient in mutT and miss-pairing left after DNA replication could not be recovered in mutL and mutS strains. Further, DNA repairing mechanism was investigated in other microorganisms; single-strand cleavage caused by exposure to BNCB radiation (boron-neutron-captured beam) could not be repaired in E. coli. Whereas for Deinococcus radiodurans, of which survival rate was not decreased by #gamma#-ray radiation at 5 ...

Energy Technology Data Exchange (ETDEWEB)

The use of gamma radiation to obtain wood-polymer composites is one of the applications of radiation that presents the most commercial interest. The process, denominated radiopolymerization, comprises the impregnation of monomers into the completely dried wood followed by exposure to gamma radiation to induce polymerization of the impregnated monomers. I this context, the present work aimed the application of this process to seven kinds of wood existing in the brazilian forests. The considered monomer is styrene and the gamma source is Cobalt-60. The obtained wood-polystyrene composites were found to have stronger static bending strength. (author)

Energy Technology Data Exchange (ETDEWEB)

Wood-plastic composites (WPC) have been prepared with five low-grade woods, native to Syria, using three monomer systems; acrylamide, butylmethacrylate, and styrene, with methanol as the swelling solvent. Polymerization was induced at various radiation doses (10, 20, and 30 kGy) at a dose rate of 3.5 kGy/h using a {sup 60}Co gamma radiation source. Some physical properties of WPC, namely polymer loading and compression strength have been measured. The polymer loading decreases approximately with increasing density of the wood species used.

International Nuclear Information System (INIS)

Wood-plastic composites (WPC) have been prepared with five low-grade woods, native to Syria, using three monomer systems; acrylamide, butylmethacrylate, and styrene, with methanol as the swelling solvent. Polymerization was induced at various radiation doses (10, 20, and 30 kGy) at a dose rate of 3.5 kGy/h using a "6"0Co gamma radiation source. Some physical properties of WPC, namely polymer loading and compression strength have been measured. The polymer loading decreases approximately with increasing density of the wood species used. (author)

International Nuclear Information System (INIS)

Short communication.

Energy Technology Data Exchange (ETDEWEB)

Plantago ovata Forsk - an economically important medicinal plant - was analyzed for trace elements and chlorophyll in a study of the effects of gamma radiation on physiological responses of the seedlings. Proton-induced X-ray emission (PIXE) technique was used to quantify trace elements in unirradiated and gamma-irradiated plants at the seedling stage. The experiments revealed radiation-induced changes in the trace element and chlorophyll concentrations.

UK PubMed Central (United Kingdom)

The issue of beam-induced damage on diffractive hard X-ray optics is addressed. For this purpose a systematic study on the radiation damage induced by a high-power X-ray beam is carried out in both...Full Text Available

International Nuclear Information System (INIS)

We have studied in detail the gamma radiation induced changes in the electrical properties of the (TeO_2)_0_._9 (In_2O_3)_0 _._1 thin films of different thicknesses, prepared by thermal evaporation in vacuum. The current-voltage characteristics for the as-deposited and exposed thin films were analysed to obtain current versus dose plots at different applied voltages. These plots clearly show that the current increases quite linearly with the radiation dose over a wide range and that the range of doses is higher for the thicker films. Beyond certain dose (a quantity dependent on the film thickness), however, the current has been observed to decrease. In order to understand the dose dependence of the current, we analysed the optical absorption spectra for the as-deposited and exposed thin films to obtain the dose dependences of the optical bandgap and energy width of band tails of the localized states. The increase of the ...

Energy Technology Data Exchange (ETDEWEB)

Short communication. 5 refs., 2 figs.

Energy Technology Data Exchange (ETDEWEB)

The analgesic, dipyrone (1,phenyl-2,3-dimethyl-5-pyrazolone-4-methylamino methane sulphonate sodium), at 20 mM concentration, inhibited the rejoining of single-strand scissions in DNA of Escherichia coli B/r cells induced by 20 krad gamma-radiation. The chemical altered the cell membrane structure as evidenced from the uptake of acriflavin, the efflux of potassium ions from the bacterial cells and the inhibition of alkaline phosphatase-a cell membrane associated enzyme. (author). 18 refs., 6 figures.

Energy Technology Data Exchange (ETDEWEB)

Wood sawdust has been applied to manufacture the sawdust-clay-plastic composite (SDCPC) by radiation process for the purpose of disposing large amount of wood sawdust waste material. The process comprises the impregnation of liquid vinyl monomers into the completely dried molded sawdust-clay specimens followed by exposure to Co-60 gamma-radiation to induce graft-copolymerization of the impregnated vinyl monomers onto the sawdust-clay matrix. The comonomer system of unsaturated polyester and vinyl compounds was found to be the ideal impregnating monomer for the preparation of the SDCPC from the viewpoint of the technological and economical advantages. The SDCPC material has a variety of the sawdust content which enables the composite to have wide range of mechanical properties, e.g., 410 to 1100 kg/cm/sup 2/ in compressive strength, 120 to 380 kg/cm/sup 2/ in tensile strength and 0.32 to 4.41 kg/mm/sup 2/ in static bending strength. The SDCPC ...

UK PubMed Central (United Kingdom)

BackgroundWe examined the effects of short-term consumption of whey protein isolate on muscle proteins and force recovery after eccentrically-induced muscle damage in healthy individuals.MethodsSeventeen...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The effect of ionizing radiation (2, 5, and 10 KGy of gamma rays) on muscle ultrastructure of grass shrimps (Penaeus monodon Fabricius) tails at ambient or frozen (-18{sup 0}C) temperature was investigated by transmission electron microscopy (TEM). No significant change was found in muscle ultrastructure of shrimp meat irradiated at doses of 2 or 5 KGy and then stored at 4{sup 0}C for 0 and 8 days. However, in shrimps which were irradiated at ambient temperature at a dose of 10 KGy, the margin of A-band of the myofibrils in longitudinal sections exhibited an irregular zig-zag pattern. In cross section some myosin filaments in the A-band regions were missing. A possible interpretation of these results would be that 10 KGy gamma irradiation dose at ambient temperature depolymerized myosin in the A-band from the tail of thick filament. Actin damage was also observed in some cross sections. Irradiation damage of sarcoplasmic membranes appeared in ...

International Nuclear Information System (INIS)

... electron spin resonance gamma radiation lipids lyophilization lysozyme radicals

International Nuclear Information System (INIS)

Published in summary form only.

International Nuclear Information System (INIS)

Recently, foods are often exposed to radiation under packed states with various wrapping materials. In this study, the effects of #gamma#-ray radiation were investigated on the additives in wrapping materials on the market. 10 - 50 kGy #gamma# radiation was irradiated to samples under sealed condition in a glass-ware. Polyethylene bag and wrapping film, polypropylene wrapping film, cup and sheet, and polystyrene cup were used as samples. And the additives in these materials were analyzed by GC/MS to evaluate the radiation effects on them. The irradiation was found to induce rapid degradation of antioxidants, especially, Irgafos 168. Some fatty acid amides used as a lubricant and a plasticizer, DBP were also reduced, but not aliphatic hydrocarbons. However, all polystyrene products used in this study included no additives. The contents of styrene dimer and trimer in those wrapping materials were not changed by ...

Science.gov (United States)

... a rotating mirror Q-switch or an acousto-optic Q-switch. The former ... Q-switch up to 2000 pps. The Q-switched output bean, is predominantly ...

International Nuclear Information System (INIS)

In radiation processing of food, the product often has to be prepackaged to prevent microbial recontamination during and after irradiation. The packaging material is exposed to radiation during radiation processing and radiation stability is a key consideration in the selection of packaging materials. The effects of ionizing radiation on many food packaging materials at the dose levels recommended for food precessing can be minimized by selecting appropriate radiation resistant materials. It is important to select materials in which chemicals formed as a result of the radiation treatment do not migrate and interact with the food, affecting its organoleptic and toxicological aspects. It is also important to select materials in which the physical properties are not altered to the extent they cannot resist damage during commercial production, shipment and storage. Radiation treatment of food may be classified broadly into two categories: 1. Processes requiring doses ...

International Nuclear Information System (INIS)

... states gamma radiation mev range 01-10 photonuclear reactions polarization

International Nuclear Information System (INIS)

... chemical radiation effects decomposition extraction columns gamma radiation

International Nuclear Information System (INIS)

... beam monitoring betatrons delay circuits errors fluctuations gamma radiation

International Nuclear Information System (INIS)

... data deuteron beams energy dependence errors gamma radiation lead 203

UK PubMed Central (United Kingdom)

Hundreds of thousands of people worldwide live or work in close proximity to steel mills. Integrated steel production generates chemical pollution containing compounds that can induce genetic damage...Full Text Available

International Nuclear Information System (INIS)

In 1998, research began at Idaho National Engineering and Environmental Laboratory to investigate the application of "6Li and "7Li isotopes to the measurement of neutron and gamma radiation. Various size pairs of "6Li and "7Li based detectors were exposed to mixed neutron and gamma radiation. Experiments demonstrated that these detectors could be used to measure low level neutron radiation in the presence of high level gamma radiation. (author)

Energy Technology Data Exchange (ETDEWEB)

An investigation was made of the accumulation of laser damage to transparent polymers irradiated with nanosecond pulses from neodymium and ruby lasers. The damage was investigated by the method of scattering and luminescence in the visible and near ultraviolet parts of the spectrum. It was established that there were two stages in laser damage by repeated irradiation with pulses of intensity below the single-shot damage threshold. An absorbing defect evolved during the first stage in such a way as to create a thermal instability in the surrounding matrix. During the second stage this thermal instability caused spatial growth of laser damage because of propagation of an ionization-inducing absorption wave with a front traveling at the rate governed by the electron component of the thermal conductivity.

DEFF Research Database (Denmark)

Pro-inflammatory cytokines may directly influence the viability and metabolic function of colonic epithelial cells (CEC) as an early event in the development of inflammatory bowel disease. We report here that TNF-alpha+IFN-gamma induced a synergistic, concentration-dependent decline in butyrate oxidation, an essential energy supply, in HT-29 and DLD-1 cells. TNF-alpha+IFN-gamma induced a parallel profound decline in cell viability in HT-29 cells, but not in DLD-1 cells, where impairment of butyrate oxidation seemed to precede later occurrence of cell damage. TNF-alpha+INF-gamma induced CEC damage was independent on NO formation and involved the IFN-gamma signalling pathway as well as induction of apoptosis. If cytokines have similar effects in vivo, these may lead to energy deficiency and thus contribute to CEC damage and disturbance of the epithelial integrity.

Energy Technology Data Exchange (ETDEWEB)

The D2 antidopaminergic drug Domperidone was evaluated singly and in combination with synthetic adrenocorticoid and an H2 antihistamine for its ability to reduce the acute emetic effects of /sup 60/Co whole-body radiation. Random-source adult male dogs were fasted 12 hours, fed a standard meal, injected 44 minutes later and irradiated 47 minutes after that. Four groups of dogs were radiated after drug injections as follows: saline (Con), domperidone (Dom), cimetidine + thiethylperazine (Cim+Thi), and dexamethasone + domperidone + cimetidine (Dex+Dom+Cim). Drug quantities for dogs represented 10 mg Dom, 10 mg Thi, 20 mg Dex, and 300 mg Cim for an average human (70 ka, 1.8 m2). Subjects were exposed on an up-down schedule to determine the radiation necessary to produce vomiting in 50% (ED50) of each group. Emesis onset times, offset times, and number of episodes were recorded. The ED50 of Dex+Dom+Cim was higher than Con. Dom produced more emetic episodes than Con or Dex+Dom+Cim. This ...

International Nuclear Information System (INIS)

Scanning spreading resistance microscopy (SSRM) has been applied to study focused ion beam (FIB) induced damage in silicon in dependence on ion irradiation doses from 10"1"2 cm"-"2 to 2#centre dot#10"1"6 cm"-"2. Starting from the lowest dose, SSRM detects increasing spreading resistance (SR) with increasing dose. For doses from 2#centre dot#10"1"3 cm"-"2 to 4#centre dot#10"1"4 cm"-"2, a slight decrease of SR is measured whereas for higher doses SR again slightly increases. The results are explained by physical effects like decreased carrier mobility due to increased scattering, amorphisation of silicon and precipitation of implanted Ga ions. The results clearly prove that SSRM is well suited for the fast detection of ion beam induced damage with high lateral resolution.

Energy Technology Data Exchange (ETDEWEB)

Inactivation of aflatoxin B1 was studied by using gamma radiation and hydrogen peroxide. A 100-krad dose of gamma radiation was sufficient to inactivate 50 micrograms of aflatoxin B1 in the presence of 5% hydrogen peroxide, and 400 krad was required for total degradation of 100 micrograms of aflatoxin in the same system. Degradation of aflatoxin B1 was confirmed by high-pressure liquid chromatographic and thin-layer chromatographic analysis. Ames microsomal mutagenicity test showed loss of aflatoxin activity. This method of detoxification also reduces the toxin levels effectively in artificially contaminated groundnuts.

International Nuclear Information System (INIS)

... alpha particles beta particles gamma radiation lead hot cells bricks shielding

Energy Technology Data Exchange (ETDEWEB)

The fundamental product of tetracycline hydrochlorine gamma radiolysis was separated in its solid state. From the results of spectroscopic studies it has been established that it is des-N,N-dimethylaminotetracycline.

International Nuclear Information System (INIS)

(1972). Germany Garratt, PG Hoigne, J. INRESCOR AG, Schwarzenbach

International Nuclear Information System (INIS)

(Jan 1974). United States Ashraf, M. Anwar, M. Siddiqui, QH Atomic Energy

International Nuclear Information System (INIS)

Portuguese 1995 1 p. Brazil Lancas, Fernando M. Vilegas, Janete HY Campos,

Energy Technology Data Exchange (ETDEWEB)

Short communication.

UK PubMed Central (United Kingdom)

Exercise training is known to induce an increase in free radical production potentially leading to enhanced muscle injury. Vitamins C and E are well known antioxidants that may prevent muscle cell damage....Full Text Available

UK PubMed Central (United Kingdom)

FRAXA is one of a number of fragile sites in human chromosomes that are induced by agents like fluorodeoxyuridine (FdU) that affect intracellular thymidylate levels. FRAXA coincides with a >200...Full Text Available

UK PubMed Central (United Kingdom)

4-Hydroxynonenal (HNE), a major electrophilic product of lipid peroxidation, is regarded as both a marker of oxidative stress and a mediator of oxidative damage. At subtoxic concentrations,...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundWe have previously reported that low concentrations of cigarette smoke extract induce DNA damage without leading to apoptosis or necrosis in human bronchial epithelial...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

UK PubMed Central (United Kingdom)

IntroductionRadiotherapy outcomes might be further improved by a greater understanding of the individual variations in normal tissue reactions that determine tolerance. Most published...Full Text Available

UK PubMed Central (United Kingdom)

Cocaine is a worldwide used drug and its abuse is associated with physical, psychiatric and social problems. The mechanism by which cocaine causes neurological damage is very complex and involves several...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

A unified physically based ion implantation damage model has been developed which successfully predicts both the impurity profiles and the damage profiles for a wide range of implant conditions for arsenic, phosphorus, BF{sub 2}, and boron implants into single-crystal silicon. In addition, the amorphous layer thicknesses predicted by this new damage model are also in excellent agreement with experimental measurements. This damage model is based on the physics of point defects in silicon, and explicitly simulates the defect production, diffusion, and their interactions which include interstitial-vacancy recombination, clustering of same type of defects, defect-impurity complex formation, emission of mobile defects from clusters, and surface effects for the first time. New computationally efficient algorithms have been developed to overcome the barrier of the excessive computational requirements. In ...

Energy Technology Data Exchange (ETDEWEB)

The damage induced by low-temperature proton irradiation in amorphous Pd/sub 80/Si/sub 20/ prepared by ion implantation is studied via electrical resistivity measurements. Our experimental results concerning the initial damage rate and the resistivity saturation are compared to the results obtained for electron and high energy /sup 16/O irradiation of amorphous Pd/sub 80/Si/sub 20/ quenched from the melt. The resistivity curve is analyzed in terms of irradiation-induced point defects.

Energy Technology Data Exchange (ETDEWEB)

Specimen damage and element loss induced by 3 MeV proton and 2 MeV alpha particle bombardment of thin sections of freeze-dried kidney tissue and embedding medium have been studied. Yields of ions scattered from H and C, and characteristic X-rays were measured versus accumulated charge, for curent densities in the range from 8x10{sup -15} to 1.1x10{sup -11} A/{mu}m{sup 2}. Structural damage, dissolouration and loss of S, Cl, C and H have been observed. Implications of this study for ion beam microanalysis of biological tissues are discussed with particular reference to the results for H loss. (orig.).

International Nuclear Information System (INIS)

Cobalt-60 gamma radiation has been found to be an effective means of immobilizing stationary phases onto gas and liquid chromatographic supports. The ability of a phase to crosslink was determined to be highly dependent on its chemical structure. Gamma radiation was employed to immobilize Se-30, a methylsilicone, and 216 PS onto Chromosorb WHP for packed column chromatography. The resultant columns exhibited increased thermal stability and a high degree of efficiency. Several blended phases containing varying ratios of Se-30:216 PS were also immobilized onto chromatographic packings. This work was further extended to the immobilization of Se-30 and 216 PS onto fused silica capillaries via gamma radiation. Columns exhibited excellent efficiency and improved thermal stability. An investigation into the role of immobilization of polymeric phases for HPLC was ...

Science.gov (United States)

Although the p53 tumor suppressor is relatively well characterized, much less is known about the functions of other members of the p53 family, p73 and p63. Here, we present evidence that in specific pathological conditions caused by exposure of normal cells to bile acids in acidic conditions, p73 protein plays the predominant role in the DNA damage response. These pathological conditions frequently occur during gastric reflux in the human esophagus and are associated with progression to esophageal adenocarcinoma. We found that despite strong DNA damage induced by bile acid exposure, only p73 (but not p53 and p63) is selectively activated in a c-Abl kinase-dependent manner. The activated p73 protein induces DNA damage repair. Using a human DNA repair PCR array, we identified multiple DNA repair genes affected by p73. Two glycosylases involved in base excision repair, SMUG1 and MUTYH, ...

International Nuclear Information System (INIS)

Boron is implanted in crystalline silicon through oxide layers with different thicknesses. The implantation is carried out at various doses and energies of interest in ultra large scale integration (ULSI) application. Rapid thermal annealings (RTA) are used to obtain shallow junctions and electrical activation of the B atoms. However, transient enhanced diffusion induced by implantation damage can be observed. The boron concentration profiles before and after annealing are obtained with secondary ion mass spectrometry (SIMS). It is found that the diffusion transient in the tail region of the boron profile increases with decreasing oxide thickness. Even more, if the implantation damage concerns mostly the oxide, i.e. when the concentration peak is located in this oxide, the oxygen knocked into the silicon substrate could play this way an important role in restricting the boron diffusion, which is good to obtain very shallow ...

International Nuclear Information System (INIS)

Presented are the investigation results of electrophysical and physico-mechanical properties of KLF-20, Viksint U-4-21, Viksint KT-73, UF-7-21, KG-184, KL-4, KL-16SE-305, VIAT-1 and PPK-21 sealants, irradiated with sources of continuous and pulse #gamma#-radiation, as well as pulse #gamma#-neutron radiation. It is shown that electrophysical and physico-mechanical properties of sealants after irradiation by continuous #gamma#-radiation up to 10"6 doses and pulse gamma-neutron radiation with neutron fluence of 10"1"3 neutron/cm"2 and #gamma#-radiation dose of 10"4R do not practically change. Electric conductivity and tangent of the angle of dielectric losses increase in the process of irradiation. Electric conductivity depends on irradiation type, is proportional to dose rate and does not depend on temperature and pulse duration.

Energy Technology Data Exchange (ETDEWEB)

A method of patterning n-type GaAs, InP, InGaAs, and InGaAsP by photoelectrochemical (PEC) etching in conjunction with a submicron focused ion beam (FIB) at low dose is described. The ion beam is used to produce damage in a desired pattern in the material. Subsequent PEC etching of the material reveals the ion induced features in relief. The procedure is highly sensitive, requiring a dose of only 5 x 10/sup 9/ ions/cm/sup 2/ for the differential etch to become apparent. The sensitivity allows rapid pattern generation in our FIB system.

Energy Technology Data Exchange (ETDEWEB)

The overall objective of this project has been to develop immunochemical methods to quantitate unique DNA base damages in order to facilitate studies on radiation-induced damage production and repair. Specifically, we have been using antibodies raised to damaged bases to quantitate unique lesions in model systems in order to evaluate their potential biological consequences. Our approach has been to synthesize modified nucleotides or nucleosides, conjugate them to protein carriers, and use the conjugates as immunogens in rabbits or to prepare monoclonal antibodies. We have been studying damages that are stable radiolysis products found in X-irradiated DNA and thus of potential biological consequence. Our aim is to build an in vitro and in vivo data base on the interactions between model DNA lesions and such cellular enzymes as DNA polymerases and repair endonucleases. Initial studies ...

British Library Electronic Table of Contents (United Kingdom)

Plastic injection molds are an important economic sector due to the increasing use of injection molded plastic components. The selection of mold steel material, its processing conditions, and the way it is machined and hardened all have an impact on how it performs during use across its lifecycle for injection molding. For this study, injection molding conditions seen during high volume manufacturing were used to induce wear that would be typical during processing. A 50wt.% glass fiber reinforced Polybutylene Terephthalate (PBT) was used for the research. After 3000 injection operations, surface damage was found only on the steel used for the stationary half of the mold cavity and the corresponding surface of the molded parts. In contrast, the moving half showed no surface damage or increa...

CERN Document Server

Monte Carlo calculations of proton irradiation of permanent magnets for the TRADE experiment have been performed. An irradiation dose of about 4´106 Gy/yr/mA has been estimated due to beam losses in normal operating conditions. Existing experimental results indicate that this irradiation level may induce a considerable demagnetization: in fact, a dose of 6´107 Gy induces a remanence loss of 0.3 % on samples of Sm2Co17 magnets, which are the most resistant type. More detailed calculations with the final design of the magnets and of the beam line are suggested, to determine if the irradiation levels allowed a reliable operation of the permanent magnets for the entire duration of the TRADE experiment. Damage and gas production rates have also been calculated; the values obtained are very low, thus confirming that the demagnetization process is in great part reversible.

Energy Technology Data Exchange (ETDEWEB)

Data are presented to support the hypothesis that the initial step in the morphologic transformation of irradiated rodent (BALB/3T3) cells is a frequent cellular event involving a large fraction of the irradiated population. This process appears to involve DNA damage, but not to represent a targeted mutation in specific structural gene(s). Morphologic transformation and immortalization appear to be distinct steps in the overall process of transformation. In contradistinction to rodent cells, immortalization is a very rare event in human diploid cells which is induced at extremely low frequencies. The hypothesis is presented that immortality develops among clones of cells bearing stable chromosomal rearrangements which emerge during the proliferation of a population of radiation damaged cells.

International Nuclear Information System (INIS)

Terminal-differential algorithm for identification of local nonhomogeneities in items under control is developed on the basis of measurements of X-ray or gamma-radiation weakening. The algorithm may be applied by developing radiation schemes of nondestructive control, identifying inadmissible inclusions in the object under study

Energy Technology Data Exchange (ETDEWEB)

This study evaluates the effect of gamma radiation on the viability of fungi and actinomycetes that contaminate medicinal plants. The relationship between the total lipids of some fungi and actinomycetes and their sensitivity to gamma radiation is also investigated. The data reveal that the viable counts of these florae decrease approximately exponentially with the radiation dose, the effective dose for the elimination of these microorganisms being about 5 kGy for all the medicinal plants under study. Response of pure cultures of fungi and actinomycetes isolated from medicinal plants to increasing absorbed doses of gamma radiation indicate that an increase in radioresistance is in the following order: Streptomyces rimosus, Fusarium solani, Nocardia kuroishii. F. oxysporum, A. fumigatus, A. flavus, A. parasiticus and A. ochraceus. The total lipid contents of ...

International Nuclear Information System (INIS)

Full text: It is known that the ion implantation of germanium single crystals at room temperature results in drastic alteration of the germanium surface and the formation of cellular relief. Voids were found into the near-surface damage layer. The intersection of these voids with the germanium surface, as result of sputter etching, forms cellular relief. However, exact mechanism responsible for formation of the voids is not known. A 10 and 30 keV Ga"+ irradiation of Ge #left brace#100#right brace# crystal at room temperature was carried out using a focused ion beam (FIB) system with a dose in the range 0.5x10"1"2 to 1.5x10"1"4 ion/cm"2. The topology of the modified germanium surface and the structure of the radiation damage was studied using imaging facilities of the FIB systems and transmission electron microscopy. The strong cellular structure of Ge was observed after an ion dose of 3x10"1"3 ion/cm"2. High-resolution TEM showed a complex ...

International Nuclear Information System (INIS)

Since 1945, more than 1.8 x 10"2"1 Bq of artificial radionuclides have been released into the atmosphere. Approximately 2.04 x 10"1"8B, i.e. approx. 0.11%, are the result of accidents at nuclear industrial facilities. This percentage is causing increased interest among researchers. This is due to the fact that in the wake of accidental release radionuclides become distributed unevenly across the Earth's surface, and the associated exposures, fluctuating from background level to several grays, an induce both stochastic and deterministic effects in the irradiated population. A comparative analysis of the medical consequences of the twentieth century's most serious nuclear events, namely the authorized dumping of high level radioactive waste into the river Techa in 1950, the explosion of a storage tank containing long lived radioactive waste in the Southern Urals in 1957, the fire at Sellafield in 1957 and the accident at the Chernobyl nuclear power plant in 1986, has ...

Energy Technology Data Exchange (ETDEWEB)

Both solvent extraction and spectrophotometric techniques were used to show the alterations that gamma radiation causes in the behavior of tetracycline molecule as far as its extracting and complexing power are concerned. The effect of gamma radiation on the solid tetracycline molecule, benzyl alcohol and on the solution of both was examined in solvent extraction systems whose aqueous phases were made up by {sup 152} Eu-{sup 154}Eu radioactive tracer solutions and whose organic phases were constituted by tetracycline-benzyl alcohol solutions. Experiments were performed in order to determine whether or not the water used for the pre-saturation of benzyl alcohol would influence the radiolysis of tetracycline. Solvent extraction and spectrophotometry were the techniques used to obtain the necessary data. Absorption spectra of irradiated tetracycline benzyl alcohol solutions submitted to several ...

International Nuclear Information System (INIS)

Redd1, a recently discovered stress-response gene, is regulated by hypoxia via hypoxia-inducible factor 1 (HIF-1) and by DNA damage via p53/p63; however, the signaling pathway by which its expression is induced by hypoxia has not been elucidated. We demonstrated that the up-regulation of Redd1 transcription by hypoxia and high cell density (HCD) depends on cooperation between Sp1 and HIF-1#alpha# downstream of the PI3K/Akt pathway.

Energy Technology Data Exchange (ETDEWEB)

Current advanced CMOS source/drain engineering involves the use of amorphizing implants with 3D geometry. Upon annealing, the induced transient enhanced diffusion (TED) can only be accurately predicted if the amorphized region is correctly modeled, as well as the formation and evolution of extended defects, particularly 3 1 1's and dislocation loops. In addition to the extended defects, already modeled in the atomistic kinetic Monte-Carlo simulator DADOS, we have developed a physically based modeling approach for the implant-induced damage build-up, amorphization and recrystallization, suitable to handle device-size process simulation. It is based on amorphous pockets (3D, irregular shape agglomerates of an arbitrary number of interstitials and vacancies, plus trapped impurities) with a size-dependent activation energy for recombination. The model is able to reproduce experimental aspects like the crystal-amorphous ...

International Nuclear Information System (INIS)

Samples prepared using the focused ion beam (FIB) inevitably contain the surface damage induced by energetic Ga"+ ions. An effective method of removing the surface damage is demonstrated using a plasma cleaner, a device which is widely used to minimize the surface contamination in scanning transmission electron microscopy (STEM). Surface bombardment with low-energy Ar"+ ions was induced by biasing the sample immersed in the plasma source, so as to etch off the surface materials. The etch rates of SiO_2, measured with a bias voltage of 100-300 V, were found to vary linearly with both the time and bias and were able to be controlled from 1.4 to 9 nm/min. The removal of the Ga residue was confirmed using energy dispersive spectroscopy (EDS) after the plasma processing of the FIB-prepared sample. When the FIB-prepared sample was processed via plasma etching for 10 min with a bias of 150 V, the surface Ga ...

International Nuclear Information System (INIS)

It is shown that low-frequency elastic vibrations of near-surface planar defects cause high-frequency ultrasonic radiation in surrounding air. The frequency conversion mechanism is concerned with contact nonlinearity of the defect vibrations and provides efficient generation of air-coupled higher-order ultraharmonics, ultrasubharmonics, and combination frequencies. The nonlinear air-coupled ultrasonic emission is applied for location and high-resolution imaging of damage-induced defects in a variety of solid materials.

Energy Technology Data Exchange (ETDEWEB)

Occupational and environmental exposure to organic ligands, solvents, fuel hydrocarbons, and polychlorinated biphenyls are linked with increased risk of hematologic malignancies. DOE facilities and waste sites in the U.S. are contaminated with mixtures of potentially hazardous chemicals such as metals, organic ligands, solvents, fuel hydrocarbons, polychlorinated biphenyls and radioactive isotopes. A major goal of this project was to establish linkage between chemical/radiation exposure and induction of genomic damage in target populations with the capability to undergo transformation.

Science.gov (United States)

Candoxin (PDB #1JGK), a three-finger neurotoxin from Bungarus candidus venom, inhibits post-synaptic neuromuscular and neuronal alpha7nACh-receptors, and induces delayed cell-death throughout the glial population. When applied to cultured human glial cell lines, candoxin (CDX) induced cell death in a concentration (EC(50) approximately 1muM) and time dependent manner. Results of TUNEL-histochemistry further confirm CDX-induced brain (hippocampus, frontal cortex, and temporal regions) damage when administered intracerebroventricularly (i.c.v) in adult mice. In this study, we explored differential gene expression profiles following exposure of human glial (Hs 683) cell lines to CDX at various time intervals using Affymetrix-GeneChips. By means of MAS and GeneSpring analyses, 105 genes whose expression was significantly (P<0.01) altered by at least 3-fold were selected. Results of the genome analysis ...

Science.gov (United States)

The epileptogenic and neurodegenerative effects of gamma-dendrotoxin, from Dendroaspis angusticeps, a specific blocker of a non-inactivating, voltage-sensitive K+ channel, were studied after focal injection into one dorsal hippocampus in rats pretreated with CGP040116, a N-methyl-D-aspartate (NMDA) receptor antagonist, and in rats bearing a monolateral surgical lesion of the Schaffer collaterals whose terminals originate from CA3 pyramids and release glutamate in the CA1 hippocampal area. Administration of 35 pmol gamma-dendrotoxin elicited in all of the treated animals (n=8) bilateral EEG discharges and damage to the hippocampal formation. Quantitation of the damage revealed significant bilateral neuronal cell loss in the CA1, CA3 and CA4 pyramidal cell layers. The lowest dose (0.35 pmol; n=4) of the toxin used did not affect EEG activity and failed to cause significant hippocampal cell loss whereas the 3.5 pmol (n=6) dose caused EEG seizures ...

Energy Technology Data Exchange (ETDEWEB)

The performance of advanced ceramics under cavitation loading in distilled water was studied by using a laboratory test with vibration-induced cavitation following the pattern of the ASTM standard G32-92. The hardened and tempered martensitic steel 100Cr6 was used as a reference. The aim was to identify mechanisms and the effects of important microstructural parameters on damage of polished Al{sub 2}O{sub 3}, Al{sub 2}O{sub 3}-ZrO{sub 2}, ZrO{sub 2} and SiC ceramics. Results showed that surface damage of brittle ceramics was mainly dominated by intergranular fracture, followed by detachment of single grains or fragments of them. Both incubation time and erosion rate were affected by the amount of initial surface cavities, grain sizes and secondary phases at grain boundaries. (orig.)

Energy Technology Data Exchange (ETDEWEB)

In principle four different methods (ultrasound, microwaves, {gamma}-radiation and x-rays) are available for the non-destructive testing of refractories. Three of these methods, i.e. ultrasound, microwaves and {gamma}-radiation, are in use by different producers of AZS materials to carry out the quality control of their products. This paper will compare the three methods on the basis of the physical properties, present the existing devices, and show the advantages as well as the limits of the different methods. {gamma}-radiography, the oldest method in use, has one main disadvantage, which is the requirement of protection against radioactive radiation. Furthermore, while cracks and cavities can be detected with this method, structural changes can not be monitored. Therefore, the ultrasonic method was developed that allows to detect variations of porosity and grain size as well as cracks and voids when the ultrasonic parameters are tuned as well ...

International Nuclear Information System (INIS)

The objective this work was to evaluate the gamma radiation processing for elimination of organic contaminants on industrial wastewater. Standard samples with 17 hydrocarbons (acetophenone, anisole, benzene, chlorobenzene, cyclohexanone, N, N-dimethylaniline, phenol, naphtalene, 1-chloronaphtalene, n-octadecane, p-nitrotoluene, toluene, tetrachloroethane, tetramethylbenzene, n-undecane, m-xylene and o-xylene) was preparated in hexane with total concentration of 1 #mu# g/ #mu# l which was analyzed by gas chromatography. Other sample with the same concentration of these hydrocarbons in acetone was used to contaminate water samples, which were irradiated with gamma radiation from Co-60 between doses 5.0 to 20.0 KGy and dose rate of 1.162 KGy/h. The activity of source was 1470 Ci. Percents destruction of hydrocarbons were: 79.76 % to 5.0 KGy, 85.97 % to 7.5 KGy, 86.24 % to 10.0 KGy, 86.72 % to 12.5 KGy, ...

Energy Technology Data Exchange (ETDEWEB)

To obtain Pinus wood-plastic composites, wood samples were impregnated with methyl methacrylate and polymerized by the use of gamma rays from a /sup 60/Co at different dose exposure and total dose. The best percentage of polymerization was obtained with the exposure of 2.0 MR of gamma radiation. It was found that the impregnation and polymerization, determined by the density values along the samples were uniform. The density became 2.6 times higher in relation to the control samples. The storage of the impregnated wood samples showed losses of the monomer, even when wrapped with aluminum or polyethylene film. It is recommended that the wood samples should be irradiated soon after impregnation.

International Nuclear Information System (INIS)

Efforts are being made to determine a gamma radiation dose for mortality of third-instar larvae of Anastrepha fraterculus which infest mangos of the Haden variety of 400 g weight. Four radiation treatments were tested: 0.4 kGy, 0.6 kGy, 0.8 kGy and 1.0 kGy. Using as a criterium for mortality the interruption of the biological cycle between larva and pupa, the following results were achieved: 49.61%, 63.33%, 74.86% and 90.72%. The percentages obtained have been corrected using the Abbot formula. When the criterium was based on no adult emergence, 100% mortality was achieved for the four treatments. (author)

International Nuclear Information System (INIS)

the cotton leaf worm, Spodoptera littoralis (boisd.) were irradiated with 100,150 and 200 Gy to induce inherited sterility. the effects of the tested doses applied to these pupae through three consequent fillial generations and the retarded influence on their F_1,F_2 and F_3 generations progeny were examined . irradiation of parental male induced damage to their daughter females ovaries. the overioles of females among P_1 ,F_1 and F_2 generations showed that the follicular epithelial cells appeared abnormal beside their limited separation from developing oocytes which became shrinked, semi absorbed or completely absorbed leaving vacuoles. the nurse cells were reduced or absent in some parts. damage was obvious through the first and second generations especially at 150 and 200 Gy. in the third generation, ovaries were not greatly affected

Science.gov (United States)

Therapeutic hypothermia is a promising method for controlling intracranial pressure (ICP) in severely brain-injured patients. However, clinical data regarding the effect of brain hypothermia on overall outcome of these patients is limited. This may be because there are specific pitfalls associated with the clinical management of induced hypothermia in patients with severe traumatic brain injury (TBI). These pitfalls may be avoided by preventing specific risk factors when cooling is induced and with rewarming. However, these risk factors have not been well systematically discussed in the literature. In this paper, three categories of clinical issues regarding the management of brain hypothermia are discussed: (1) stress-induced secondary brain injury mechanisms; (2) technical aspects of intensive care unit (ICU) cooling management; and (3) rewarming rates and methods. For patients with a Glasgow Coma Scale (GCS) score of ...

International Nuclear Information System (INIS)

In defining criteria for good protection against ionizing radiation, it is important to assess quantitatively the likely risk of any radiation exposure. The 'somatic' risks to the individual result mainly from induction of cancer in the organs irradiated, and these risks can now be estimated on the basis of numerous detailed epidemiological surveys of exposed human populations. Estimates of the risk of hereditary effects, from genetic changes induced in germ cells, are based largely on the frequency with which such effects are induced in other species. In both cases the risk at very low dose can be inferred using knowledge of the way in which radiation damage is caused in tissues. Coherent systems of radiation protection are based on a restriction of doses to the whole body and to individual organs, such that the induction of cancer and genetic harm is infrequent, and the threshold dose for causing other, 'non-stochastic', ...

International Nuclear Information System (INIS)

Ferrite of system, namely Ni_1_-_xZn_xFe_2O_4 with x = (0.0, 0.2, 0.4, 0.6, 0.8, 1.0), have been prepared by solid state reaction to investigate the effect of gamma rays irradiations using Co"6"0 source on the cation distribution, structural and magnetic properties. The unirradiated and irradiated samples were then subjected to characterization techniques such as X-ray diffraction, magnetization and AC susceptibility. The results of these characterizations are found to be different for irradiated from that of the pristine sample. The modifications in respect of irradiated samples are explained in terms of the ion-induced disorder. The important result of #gamma#-irradiation on the cation distribution, structural and magnetic properties is the change of ratio Fe"2"+/Fe"3"+. Possible reasons on the results are proposed.

International Nuclear Information System (INIS)

In this paper, probabilistic safety assessment (PSA) of the station blackout (SBO) and 5th emergency diesel in Daya Bay NPP has been carried out, the calculation method of non-recover factors of power supplies is given, and sensitivity analysis on the connection duration of 5th emergency diesel has been executed. It is concluded that the core damage frequency (CDF) induced by SBO is relatively large, the addition of 5th emergency diesel is very helpful for the CDF reduction, and the connection duration of this diesel has great effect on the CDF reduction

British Library Electronic Table of Contents (United Kingdom)

Abstract Neurodegenerative and neurometabolic disorders may cause significant morbidity and mortality in children. Imaging is important in early diagnosis of metabolic disorders and in determining the extent of brain injury. Especially after the development of new techniques such as diffusion-weighted magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS), neuroimaging plays more important role in the diagnosis and management of these disorders. In these disorders, usually a mutation causes a clinically significant block in one or more metabolic pathways. This blockage usually results in either a deficiency of the product or in an accumulation of substrate with damage induced by either storage or toxicity. The presenting symptoms are usually nonspecific. In some of the ...

Energy Technology Data Exchange (ETDEWEB)

Austenitic 316LN alloy was ion-irradiated using the unique Triple Ion Beam Facility (TIF) at ORNL to investigate radiation damage effects relevant to spallation neutron sources. The TIF was used to simulate significant features of GeV proton irradiation effects in spallation neutron source target materials by producing displacement damage while simultaneously injecting helium and hydrogen at appropriately high gas/dpa ratios. Irradiations were carried out at 80, 200, and 350 C using 3.5 MeV Fe{sup ++}, 360 keV He{sup +}, and 180 keV H{sup +} to accumulate 50 dpa by Fe, 10,000 appm of He, and 50,000 appm of H. Irradiations were also carried out at 200 C in single and dual ion beam modes. The specific ion energies were chosen to maximize the damage and the gas accumulation at a depth of {approximately} 1 {micro}m. Variations in microstructure and hardness of irradiated specimens were studied using transmission electron ...

UK PubMed Central (United Kingdom)

The titers of several preparations of kuru. Creutzfeldt-Jacob disease, and scrapie viruses were reduced by only 1/10th or less by high doses of gamma radiation of 50 kGy and by only 1/10th-1/1000th...Full Text Available

International Nuclear Information System (INIS)

Practical procedures were developed for large-scale microbial decontamination of dry egg powder and gelatine with gamma radiation ("6"0Co). The formation and lifes of free organic radicals in these materials were examined by ESR measurements of powder samples. The concentration of these radicals was studied in dependence on the time of storage. Secondary oxidation of egg fats by air oxygen was investigated. Sensoric tests of irradiated gelatine, both in powder and hydrogel form, were performed. (author). 4 figs., 2 tabs., 2 refs.

Energy Technology Data Exchange (ETDEWEB)

The neutron detector is cased in a metal envelop and has one detector with a very sensitive fission chamber and a second detector with a fission chamber less sensitive that the first one and a boron coated ionisation chamber for reducing gamma radiation detection.

International Nuclear Information System (INIS)

A method for the analysis of three-component mixtures is described. The method is used for contact-free determination of component concentration in the mixtures transported via a product duct. Formulae as an aid in choosing the gamma radiation source and estimating the efficiency of measurement are given. The errors of measurement by the method of formaline-water-carbamide mixture is 1-2 %. 9 refs.; 1 fig.

International Nuclear Information System (INIS)

In order to qualify corrosion resistant materials for high level waste (HLW) packagings acting as a long-term barrier in a rock salt repository, the corrosion behaviour of the preselected materials Ti 99.8-Pd, Hastelloy C4 and two unalloyed steels was investigated. The resistance of the materials to general corrosion, local corrosion and stress corrosion cracking was examined under postulated accident conditions in the repository by long-term immersion tests of up to 4 years duration and electrochemical methods. The parameters investigated were different salt brines, temperatures of 90 deg. C, 170 deg. C and 200 deg. C as well as a gamma radiation field of 10"3Gy/h (10"5rad/h). Among the materials studied, Ti 99.8-Pd exhibited the highest corrosion resistance. This material corroded at a very low rate (gamma radiation, and proved to be resistant to local corrosion and ...

Energy Technology Data Exchange (ETDEWEB)

The Albedo Theory was applied in order to develop an one-group algorithm for coupled neutron-gamma shielding calculations. The configuration analyzed consists of multilayered plane systems, where a incident neutron current generates gamma radiation through neutron-gamma reactions. The results obtained by Albedo Method and ANISN code have shown excellent agreement. (author)

International Nuclear Information System (INIS)

Although low-energy ion radiation has been proven to have a wide range of biological effects and led to fruitful achievements as a new mutagenic source for genetic modification, there still exist some disputes about its mutagenic mechanisms because of its short-penetrating property. In present research, Arabidopsis thaliana transgenic for GUS recombination substrate was used to evaluate the genomic instability induced by irradiations of alpha particle (3.3MeV) and Low-energy-Argon ion (30 KeV). A pronounced effects of alpha particle irradiation to Arabidopsis thaliana seedlings and Argon ion irradiation to seeds on the somatic homologous recombination frequency (sHRF) were reported. The sHRFs increased 1.88-fold and 2.42-fold, respectively, which indicated that the short-penetrating radiation could effectively induce the plant genomic instability in either dry seeds or seedlings with active metabolism. The local alpha particle irradiation of ...

Energy Technology Data Exchange (ETDEWEB)

Alloy 800 has been proposed for use in the receiver tube panel arrays of advanced solar central receiver (SCR) designs. In this application the alloy will be exposed to a molten mixture of sodium and potassium nitrate salts at temperatures ranging up to approximately 600/sup 0/C While these salts are routinely used in a variety of applications including metal heat treating and process heat transfer, common industrial experience has been limited to maximum temperatures of 400/sup 0/C - 450/sup 0/C. There is, therefore, considerable interest in the compatibility of these salts with containment alloys at the higher temperatures associated with SCR designs. Additionally, the containment alloy may be subject to thermally induced fatigue damage resulting from intermittent cloud cover and diurnal cycling. Previous work has found that slower near-threshold fatigue crack growth rates (FCGR) in Alloy 800 result when it is tested in molten nitrate salt at ...

Scientific Electronic Library Online (English)

Abstract in english BACKGROUND: Severe pathogenic infection triggers excessive release of cytokines as part of the massive inflammatory response associated with septic shock. OBJECTIVES: To investigate the protective effect of caffeic acid phenethye ester (CAPE) against lipopolysaccharide (LPS) induced endotoxemia, hepatic and neuronal damage and the associated systemic inflammatory response (SIR). METHODS: Fifty male Wister rats were divided into: control, LPS, and CAPE+LPS groups. Plasma c (more) oncentrations of various cytokines, including TNF-?, IL-1?, IL-1?, IL-6, IL-4, IL-10, and sICAM-1 were evaluated. In addition, the histopathological changes in the hepatic and neural cells were assessed. RESULTS: The LPS group showed high inflammatory cytokines and sICAM-1 levels reflecting the presence of SIR. Hepatocyte necrosis, apoptosis, extensive hemorrhage and inflammatory cellular infiltration together with brain astrocytes swelling, early ...

International Nuclear Information System (INIS)

Neuronal cell death induced by oxidative stress is correlated with numerous neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), and stroke. The causes of sporadic forms of age-related neurodegenerative diseases are still unknown. Recently, a correlation between paraquat exposure and neurodegenerative diseases has been observed. Paraquat, a nonselective herbicide, was once widely used in North America and is still routinely used in Taiwan. We have used differentiated Human Neuroblastoma (SHSY-5Y) cells as an in vitro model to study the mechanism of cell death induced by paraquat. We observed that paraquat-induced oxidative stress in differentiated SHSY-5Y cells as indicated by an increase in the production of cellular reactive oxygen species (ROS). Furthermore, apoptosis was evident as indicated by cellular and nuclear morphology and DNA fragmentation. Interestingly, pretreatment of ...

Energy Technology Data Exchange (ETDEWEB)

Rat lung and liver microsomes did not undergo lipid peroxidation in the absence of iron when incubated with NADPH and concentrations of paraquat ranging from 10/sup -7/ to 10/sup -2/ M. Paraquat also did not stimulate rat liver and lung microsomal peroxidation induced by added iron and NADPH, and was inhibitory at concentrations above 10 ..mu..M. Similarly, no stimulation of peroxidation was produced by paraquat in rabbit or human lung microsomes; however, under similar conditions, paraquat enhanced NADPH/iron-dependent peroxidation in mouse lung and liver microsomes obtained from rats sacrificed at 12, 18, and 24 hr following a lethal dose of paraquat (50 mg/kg, ip), there was no loss of vitamin E or increase in susceptibility to in vitro peroxidation which would be expected if lipid peroxidation had occurred in vivo although extensive lung damage developed during this time period. These results indicate that paraquat does not cause pulmonary ...

International Nuclear Information System (INIS)

Full text: An adaptive response is a decreased biological effect induced by a priming radiation dose given prior to a challenge dose. Adaptive responses contradict the linear-nothreshold model of risk estimation. The pKZ1 mouse chromosomal inversion assay is an extremely sensitive assay for studying the mutagenic effect of low dose radiation. A non-linear dose response for chromosomal inversion has been observed in pKZ1 spleen and prostate after a single whole body irradiation with doses between 1?Gy and 10mGy. Doses between 5-10?Gy resulted in an induction in inversions and doses between 1-10mGy resulted in a reduction below endogenous inversion frequency. These results suggest that doses in the 1-10 mGy range cause host responses which overcompensate by not only preventing inversions that would normally occur as a result of the low doses of radiation but also by preventing some of the endogenous inversions that would have occurred in the absence of radiation. It ...

International Nuclear Information System (INIS)

An attempt has been made to grow L-tartaric acid nicotinamide (LTN); a complex of tartaric acid, by employing a modified unidirectional method. The crystalline structure and quality are investigated by single crystal XRD and rocking curve studies. The linear and nonlinear optical properties are studied by UV-vis-NIR spectral analysis, SHG test, phase matching and laser induced damage threshold measurement. For comparison, parallel growth of the crystal was carried out by conventional method and the properties of the LTN samples grown by the conventional and unidirectional methods are investigated. The mechanical, photoconductivity and dielectric behavior of LTN crystals are also investigated.

British Library Electronic Table of Contents (United Kingdom)

In Indian traditional medicine, various plants have been used widely as a remedy for treating snakebites. The aim of this study was to evaluate the effect of Tamarindus indica seed extract on the pharmacological as well as the enzymatic effects induced by V. russelli venom. Tamarind seed extract inhibited the PLA2, protease, hyaluronidase, L-amino acid oxidase and 5prime-nucleotidase enzyme activities of venom in a dose-dependent manner. These are the major hydrolytic enzymes responsible for the early effects of envenomation, such as local tissue damage, inflammation and hypotension. Furthermore, the extract neutralized the degradation of the Bb chain of human fibrinogen and indirect hemolysis caused by venom. It was also observed that the extract exerted a moderate effect on the clotting ...

British Library Electronic Table of Contents (United Kingdom)

Modifications of the structure and mechanical properties in LiF crystals irradiated with MeV-energy Au ions have been studied using nanoindentation, atomic force microscopy and optical spectroscopy. The nanostructuring of crystals under a high-fluence irradiation (above 1013 ions/cm2)?was?observed. Nanoindentation tests show a strong ion-induced increase of hardness (up?to 150?200%), which is related to the high volume concentration of complex color centers, defect aggregates, dislocation loops and grain boundaries acting as strong barriers for dislocations. From the?depth profiling of the hardness and energy loss it follows that both nuclear and electronic stopping mechanisms of MeV Au ions contribute to the creation of damage and hardening. Whereas the electronic stopping is dominating i...

Energy Technology Data Exchange (ETDEWEB)

We have investigated the diffusion of Sb in Si in the presence of defects injected by high-energy implantation of Si ions at room temperature. MeV ion implantation increases the concentrations of vacancies, which induce transient-enhanced diffusion of Sb deposited in Si. We observed a significant enhancement of Sb diffusion. Secondary ions mass spectroscopy has been performed on the implanted samples before and after annealing. Rutherford-backscattering spectrometry has been used to characterize the high-energy implantation damage. By fitting diffusion profiles to a linear diffusive model, information about atomic scale diffusion of Sb, i.e. the generation rate of mobile state Sb and its mean migration length were extracted.

Science.gov (United States)

Not Available

Energy Technology Data Exchange (ETDEWEB)

The present study discusses the contribution of the adoption of more rigorous and objective criteria to the selection and analysis of information sources, leading to more scientific rigour when registering phytotherapic drugs. To this end, it is herein proposed the adoption of a previously tested and acknowledged methodology, namely the Systematic Revision, as a standard for phytotherapic drug analyses. In order to show differences brought about by the Systematic Revision during the registration procedures of phytotherapic drugs, the case of the Maytenus ilicifolia (known popularly in Brazil as 'espinheira-santa') is presented. As it is well known, the use of ionizing radiation is expanding, especially in medicine and pharmacy. Therefore, gamma radiation was applied to the microbiological quality control of phytotherapic matrices. Results indicated a positive contribution of Systematic Revision to the registration procedures ...

Energy Technology Data Exchange (ETDEWEB)

Composites based on pure gypsum and polyester-styrene resin have been prepared using various doses of gamma radiation. Some physical properties of the prepared composites and the influence of irradiation dose on it have been studied as: compression strength, hardness, thermal decomposition temperature in nitrogen or oxygen, and the change in weight in aqueous solutions with different pH values. The glass transition temperature of the pure polymer and the composites increases with increasing the irradiation dose up to a plateau, and the glass transition temperature of the pure polymer is lower than that of the composites. The irradiation dose does not seem to affect the decomposition temperature of the pure polymer or the composites significantly and the decomposition temperature in presence of nitrogen is higher than that in presence of oxygen. Increasing the irradiation dose leads to an enhancement of the compression strength of the pure ...

Energy Technology Data Exchange (ETDEWEB)

The use of linear accelerators in radiotherapy is of great importance in Medicine, and according to international recommendations the electron beam dosimetry has to be performed using plane-parallel ionization chambers, previously calibrated in standard gamma radiation fields at accredited laboratories. In this work, calibration methods of plane-parallel ionization chambers used in dosimetry procedures of high energy electron beams of clinical accelerators were presented, tested and intercompared. The experiments were carried out using gamma radiation beams of {sup 60} Co at the Calibration Laboratory of Clinical Dosemeters at IPEN and electron beams od 4 to 16 MeV at the Radiotherapy Department of Hospital Israelita Albert Einstein, Sao Paulo. A method was chosen to be established at IPEN. Proposals of the calibration procedure, calibration certificate and data sheets are presented. (author)

International Nuclear Information System (INIS)

It has been prepared composites materials by means of monomer penetration in pores of wood samples and later curing by means of gamma irradiation. The studied species were Hura crepitans L. (catahua), Aniba puchury-minor (C. Martinez) (mohena amarilla), and Calycophyllum spruceanum (Benth.) (capirona). These new materials exhibit smaller water absorption and better mechanical properties in comparison with native wood. The test tubes of catahua treated with the styrene-polyester mixture absorb only up to 10% humidity compared to the native species whereas its hardness is increased in a 100%. (author).

International Nuclear Information System (INIS)

In view of the interest in the use of gamma irradiation to extend the storage life of pre-packaged foods a report is made on the effects of gamma radiation on the migration of Irganox 1076 and Irganox 1010, antioxidants present in food packaging plastics, into synthetic triglyceride fatty-food simulant HB307 and iso-octane. The extent of migration was assayed by h.p.l.c. techniques. Migration into HB307 and iso-octane decreased steadily as irradiation progressed suggesting that gamma irradiation of packaging materials helps to prevent the contamination of food by antioxidants in the packaging. (U.K.).

Energy Technology Data Exchange (ETDEWEB)

Radiological hazard in uranium mining and milling operations are primarily due to exposure to external beta and gamma radiation as well as to airborne radionuclides which consist of radon and its short-lived daughter products. In May 1981 a radiological survey programme was performed in order to make a general assessment of the radiation hazards associated with the uranium mines and the Uranium Pilot Plant operated by the M.T.A. Institute in the Koprubasi district of the Manisa province. In this paper a preliminary radiological risk evaluation attempt is presented based on the radiation and radioactivity measurements performed in this district in May 1981.

International Nuclear Information System (INIS)

The #gamma#-radiation following thermal neutron capture in "1"0"0Mo has been studied by singles and coincidence measurements. A "1"0"1Mo level scheme has been deduced and is compared with the results of previous (d,p), (n,#gamma#) and "1"0"1Nb decay studies. The existence of the first excited state at 13.51 keV has been confirmed. The present data yield a neutron binding energy of 5398.4 KeV. (Auth.).

Energy Technology Data Exchange (ETDEWEB)

The polymerization of vinyl pyrrolidinone on nylon 66, with the assistance of aqueous phenol and formic acid, was investigated by mutual and post irradiation procedures. Both solvents were found to greatly facilitate the polymerization with the post irradiation procedure, whereas neither presented any advantage with the mutual irradiation procedure. Tensile properties of the modified fibers were affected in similar ways by both the irradiation procedures and solvents in that the only notable changes were the somewhat higher extensions at yield and at break. The moisture regain values of the treated yarns and fabrics were increased up to three-fold. Surface morphology of the modified fibers was revealed by SEM.

International Nuclear Information System (INIS)

A calculation method of the X-ray radiation dose (energy of gamma- radiation remains in the range of energies where the mechanism of photoelectric absorption is the prevailing one) absorbed in the absorbers of final thickness is suggested. Calculations of resorption of secondary radiation (characteristic fluorescences) in the substance and kinetic energy of photoelectrons caused by this resorption (it would be enough to consider one or two hard series) are presented. Calculation of the spectrum of photoelectron energy yield in TeInSe_2 monocrystal for 0.1-0.5 A range of X-ray radiation is conducted by the developed methods.

International Nuclear Information System (INIS)

The effect of a substrate on the results of measuring tantalum coating thickness in two-layer compositions according to gamma radiation scattered by the substrate is studied. It is shown that by means of an albedo-radiometer realizing the physical model absorber-scatterer one can determine the thickness (application uniformity) of tantalum coatings up to 150-300 #mu#m depending on the substrate material (plexiglas, aluminium, iron, copper). In case of testing coatings on substrates of alloys and high-alloy steels in order to ensure high accuracy of measrurement it is expedient with the above albedo-radiometer to determine the value of the backscattered radiation flux for the substrate before coating application.

International Nuclear Information System (INIS)

Treatment of food with low doses of gamma radiation has been recognized to have two main advantages. These consist of: (1) improvement of food safety by elimination of pathogens and (2) reduction of microbial spoilage and extension of shelf life of perishable items by reducing the number of viable spoilage organisms. Studies during the last few decades have conclusively proved the beneficial effects of radiation with respect to fishery products. The three potential areas of application to fish products include: (i) radurization for shelf life extension (ii) radicidation to eliminate food borne pathogens in the products and (iii) radiation treatment to dried products to control insects.

International Nuclear Information System (INIS)

Oxide superconducting thin films were irradiated with X-rays and ultra-violet (UV) light, and induced radiation effects on electrical and chemical properties were examined by transport measurement, X-ray diffraction analysis (XRD), diamagnetization measurement and X-ray photoemission spectroscopy (XPS). After irradiation for ErBa_2Cu_3O_x films with X-rays emitted from a Rh tube for 100 hours, superconductivity was remarkably damaged, destroying the zero-resistance state. The UV-light irradiation for Bi_2Sr_2CaCu_2O_x films was performed in He gas of about 500 Pa with a low pressure mercury lamp. The superconductivity was gradually degraded with the UV irradiation time up to 70 minutes. In both cases, adequate oxygen-annealing treatments restored superconductivity. The X-ray photoemission spectra showed that the mean Cu valence of the films was decreased approximately from +2 to +1 by the irradiation. From these results we can find that ...

International Nuclear Information System (INIS)

We have investigated the characteristics of ion-beam-induced spontaneous etching (IBISE) of GaAs in Cl_2 ambient by using a Ga-focused ion beam (FIB) with an energy ranging from 3 to 15 keV. The etched depth of the irradiated region was more than 20 times greater than that of unirradiated region. When the sputtered depth by FIB irradiation amounted to around 8 A at each ion energy, the etched depth in Cl_2 ambient for 1 hour became saturated. The saturated etched depths were 450, 550, 750 and 800 A at the ion energy of 3, 5, 10 and 15 keV, respectively. The residual damage of the etched surface was also investigated by photoluminescence (PL) measurement. The maximal PL intensity was obtained at around the threshold dose of IBISE and increased with decreasing ion energy. The full recovery of PL intensity was observed at the ion energy of 3 keV after annealing at 400degC. (author).

Energy Technology Data Exchange (ETDEWEB)

The research had as objective the use of the gamma radiation of the Cobalto-60 as quarantine treatment of the medicinal plant, aromatic and seasoning plants dehydrated infested by Lasioderma serricorne and Plodia interpunctella determining the disinfestation doses to attend the criterion in the not emergency of adults of the species in study and analysing through the Chromatography of Thin Layer the effect of the gamma radiation of the cobalto-60 on the active principle of extract dehydrated of Chamomilla recutita, Pimpinella anisum, Origanum vulgare, Cymbopogon citratus, Ocimum basilicum and Thymus vulgaris. The work was developed in the Laboratorio de Inseticidas in the Instituto Biologico in Sao Paulo in the period of August of 2005 the June of 2007. The radiation source used gamma was an experimental irradiator of Cobalto-60, model Gamacell 220, located in the Instituto de Pesquisas Energeticas e ...

International Nuclear Information System (INIS)

Shielding calculations for neutron-gamma radiation are usually done by using the full Theory of Transport or the Monte Carlo Techniques. After some works based on the Albedo Method, the shielding calculations for neutron-gamma radiation have a reliable tool with great didactical value which shows its clarity and simplicity for the resolution of cases that involve neutrons and photon shielding in nonmultiplying media. The excellent results of these works have motivated the elaboration and the development of this study that will be presented in this dissertation. The balance of a neutronic current entering a shield of two layers considering the coupling neutron-gamma will be determined by the Albedo Method. The shield will be composed of a layer of iron and another one of manganese with 10 cm of thickness each. The arrays of the materials coefficients will be obtained from the ANISN code. ANISN is a one ...

International Nuclear Information System (INIS)

The principal mathematical tools frequently available for calculations in Nuclear Engineering, including coupled neutron-gamma radiations shielding problems, involve the full Transport Theory or the Monte Carlo techniques. The Multigroup Albedo Method applied to shieldings is characterized by following the radiations through distinct layers of materials, allowing the determination of the neutron and gamma fractions reflected from, transmitted through and absorbed in the irradiated media when a neutronic stream hits the first layer of material, independently of flux calculations. Then, the method is a complementary tool of great didactic value due to its clarity and simplicity in solving neutron and/or gamma shielding problems. The outstanding results achieved in previous works motivated the elaboration and the development of this study that is presented in this dissertation. The radiation balance resulting from the incidence of a neutronic ...

International Nuclear Information System (INIS)

Full - grown pupae of the cotton leaf worm Spodoptera littorals (Boisd.) were gamma - irradiated with low doses of 25,50,75, or 100 Gy for male line and with 50 or 100 Gy for female line . The effects on reproduction, development and sex ratio were the biological aspects studied among P1,F1,F2 and F 3 generations . Also, the effects of dose accumulation applied grown male pupae through two or three filial generations and the retarded influence on their F1,F2,and F 3 progeny were examined. In another trial the histological examinations for ovaries and testes of irradiated parents and for their generation were made . The F1 males were more sterile than irradiated parental males while F1 females were more fertile than their irradiated parental females. Irradiation of P1 males did not clearly affect neither the percentage of mated females nor the average number of spermatophores per mated female among the individuals of P1,F1,F2 and F 3 generations. Irradiation of P1 females did not affect ...

Energy Technology Data Exchange (ETDEWEB)

Correlation between mechanical stress and hydrogen effects on radiation damage in polycide-gate MOS capacitors was investigated as a function of gate-oxide thickness. The compressive stress magnitude was altered by varying the silicide (TiSi/sub 2/ or WSi/sub 2/) thickness in the polycide-gate electrode, and hydrogen introduction into gate-SiO/sub 2/ film was carried out by diffusion from plasma-deposited silicon-nitride passivation film (SiN-Cap). In a MOS capacitor without passivation film (No-Cap sample), it was found that compressive stress on gate-SiO/sub 2/ reduces both positive charge build-up (..delta..Qot) and interface-trap generation (..delta..Dit). Radiation induced shift, ..delta..Qot exhibits a smaller stress effect as compared with ..delta..Dit. As gate-SiO/sub 2/ thickness decreases, the stress effect on ..delta..Qot increases, while this effect on ..delta..Dit remains nearly constant. This compressive stress effect was ...

International Nuclear Information System (INIS)

Flow-induced vibration is an important concern to the designers of heat exchangers subjected to high flows of gases or liquids. Two-phase cross-flow occurs in industrial heat exchangers, such as nuclear steam generators, condensers, and boilers, etc. Under certain flow regimes and fluid velocities, the fluid forces result in tube vibration and damage due to fretting and fatigue. Prediction of these forces requires an understanding of the flow regimes found in heat exchanger tube bundles. Excessive vibrations under normal operating conditions can lead to tube failure. Relatively little information exists on two-phase vibration. This is not surprising as single-phase flow induced vibration; a simpler topic is not yet fully understood. Vibration in two-phase is much more complex because it depends upon two-phase flow regime, i.e. characteristics of two-phase mixture and involves an important consideration, which is the void ...

Science.gov (United States)

PNAS-4, a novel pro-apoptotic gene activated during the early response to DNA damage, can inhibit proliferation via apoptosis when overexpressed in some tumor cells. Recent studies have indicated that honokiol can induce apoptosis, inhibit angiogenesis, and suppress tumor growth. In the present study, we investigated whether mouse PNAS-4 (mPNAS-4) could augment the apoptosis of tumor cells induced by honokiol in vitro, and whether the antiangiogenic activity of honokiol and induction of apoptosis by mPNAS-4 could work cooperatively to improve the antitumor efficacy in vivo. In vitro, mPNAS-4 inhibited proliferation of murine colorectal carcinoma CT26 and Lewis lung carcinoma LL2 cells through induction of apoptosis, and significantly augmented the apoptosis of CT26 and LL2 cells induced by honokiol. Compared with treatment with mPNAS-4 or honokiol alone, in vivo systemic administration of an expression ...

UK PubMed Central (United Kingdom)

DNA damage is a threat to genomic integrity in all living organisms. Plants and green algae are particularly susceptible to DNA damage especially that caused by UV light, due to their light dependency...Full Text Available

Science.gov (United States)

Wade. Jackson. - Army. VTD at NASA. Langley. ABSTRACT. Panel size has a large effect on the impact response and resultant damage level of honeycomb sandwich ...

UK PubMed Central (United Kingdom)

PurposeCataracts are often considered to be an unavoidable consequence of aging. Oxidative damage is a major cause or consequence of cortical and nuclear cataracts, the most common...Full Text Available

International Nuclear Information System (INIS)

General mechanisms of radiation damage to biomolecules was studied by using substituted pyrimidines, particularly barbituric acid derivatives.

International Nuclear Information System (INIS)

In the Peruvian natural forest there are several kind of woods, some of those are not of commercial interest, because have not resistance at termites and wet, are too soft, or can not be well finished, in the others. The present work is devoted to improvement of the physical properties of wood, such as hardness, traction, wet resistance, etc., by means of the generation of a composite wood-polymers cured by using gamma irradiation. The main objective is to establish the main parameters for the polymerization process (economic technical aspect) that decrease the amount of water absorption, in consequence the volumetric variation of Catahua, Mohena and Capirona woods. Gamma irradiation also provides good protection against the biological agents. In consequence, these woods increase its intrinsic and economic values. (author)

CERN Document Server

The development of a replacement to the conventional film based X-ray imaging technique is required for many reasons. One possible route for this is the use of a large area film of a suitable semiconductor overlaid on an amorphous silicon readout array. A suitable semiconductor exists in cadmium telluride and its tertiary alloy cadmium zinc telluride. In this thesis the spectroscopic characteristics of commercially available CZT X- and gamma-radiation detectors are established. The electronic, optical, electro-optic, structural and compositional properties of these detectors are then investigated. The attained data is used to infer a greater understanding for the carrier transport in a CZT radiation detector following the interaction of a high energy photon. Following this a method used to fabricate large area films of CdTe on a commercial scale is described. This is cathodic electrodeposition from an aqueous electrolyte. The theory and experimental arrangement for ...

International Nuclear Information System (INIS)

The main points of quality control methods and technique of environmental radiological baseline study of Guangdong Daya Bay Nuclear Power Station are reported. Results of intercalibration of international and inland laboratories are given. The random chosen samples are checked and compared with two measurement methods. The data obtained in Daya Bay environment are put to the correlation statistics test using the linear regression analysis method between the correlative items such as "4"0K activity by gamma spectrum measurement and potassium content by chemical analysis, total #alpha#(#beta#) activity and nuclide content, as well as environmental gamma radiation dose rate and TLD accumulation dose. The data of Daya Bay environmental radioactivity baseline level show good concordance and reliability.

International Nuclear Information System (INIS)

A wood-polymer composite has been produced by impregnating the wood with the monomer and subsequently polymerizing it by exposure to a gamma radiation source. To compare the improvement in creep deformation of the wood due to the polymer impregnation, a nonlinear Norton-Bailey isothermal mathematical function has been used to model the bending creep deformation of the wood-polymer composites. Results show that the impregnation significantly improves the creep resistance of the wood. The maximum creep resistance is obtained when the amount of polymer impregnation exceeds about 30%. An interfacial interaction between the wood cell wall and the polymer could explain the creep deformation improvement, as well as the maximum impregnation level beyond which little improvement occurs. The results indicate that polymer impregnation is a viable method for improving the poor creep properties of wood. (author).

Energy Technology Data Exchange (ETDEWEB)

The mass and charge distributions in an unseparated mix of fission product nuclei from thermal-neutron fission of /sup 242m/Am were studied through semiconductor gamma-ray spectrometry. Samples of the fissionable material under study were irradiated in a vertical irradiation tube of the MIFI IRT research reactor. Following irradiation, measurements were made on aperture-calibrated semiconductor detectors. For broader identification of fission fragment nuclides three experiments were conducted that differed substantially in irradiation duration. The spectrum of gamma radiation from the mix of fission products and the time dependences of count rate at total absorption peaks were analyzed on SM-4 and Iskra-226 computers. The values of yields obtained were compared with data of investigations conducted earlier with other experimental methods, and also with the results of calculations.

Energy Technology Data Exchange (ETDEWEB)

Kinetics of postradiation polymerization of triethylene glycol ..cap alpha.., ..omega..-dimethacrylate has been studied by calorimetric method. The low-temperature radiolysis has been studied by ESR method. The radiation-chemical yield of radicals on ..gamma..-irradiation by /sup 60/Co is determined being equal to 6+-1 1/100 ev. Transformation of the radicals spectrum into the spectrum of propagating macroradicals proceeds at 140 K. After the transition from glassy to liquid state (Tsub(g)=193 K) the intensive postpolymerization begins. During the polymerization the disappearance of radicals is observed. For the low-temperature region the effective activation energy of polymerization is determined beina equal to 50.7+-0.8 kJ/mol.

Energy Technology Data Exchange (ETDEWEB)

Ford, Bacon and Davis Utah Inc. has reevaluated the Tuba City site in order to revise the March 1977 engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Tuba City, Arizona. This engineering assessment has included the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and radiation exposures of individuals and nearby populations, the investigations of site hydrology and meteorology, and the evaluation and costing of alternative corrective actions. Radon gas released from the 0.8 million tons of tailings at the Tuba City site constitutes the most significant environmental impact, although windblown tailings and external gamma radiation also are factors.

International Nuclear Information System (INIS)

The virucidal effect of _6_0Co gamma radiation was studied in cell culture medium and in liquid swine manure involving the most important porcine viruses that can be spread by liquid manure. The radiation doses (20 kGy and 30 kGy) were determined in preliminary experiments employing a porcine enterovirus from the serogroup 1 (Teschen group). In the main experiment, the following viruses were employed: swine vesicular disease (SVD) virus, type C foot-and-mouth disease (FMD) virus, a field strain of Aujeszky's disease (AD) virus, transmissible gastroenteritis (TGE) virus, as well as bovine viral diarrhoea (BVD) virus. The latter strain served as a model for hog cholera virus. The results of the experiments indicate that safe disinfection of the virus infected liquid swine manure by ionizing radiation requires a radiation dose of 30 kGy. (author).

International Nuclear Information System (INIS)

Transmission electron microscope (TEM) specimens are today routinely prepared using focussed ion beam (FIB) instruments. Specifically, the lift-out method has become an increasingly popular technique and involves removing thin cross-sections from site-specific locations and transferring them to a TEM grid. This lift-out process can either be performed ex situ or in situ. The latter is mainly carried out on combined dual-beam FIB and scanning electron microscope (SEM) systems whereas conventional single-beam instruments often are limited to the traditional ex situ method. It is nevertheless desirable to enhance the capabilities of existing single-beam instruments to allow for in situ lift-out preparation to be performed since this technique offers a number of advantages over the older ex situ method. A single-beam FIB instrument was therefore modified to incorporate an in situ micromanipulator fitted with a tungsten needle, which can be attached to a cut-out FIB section using ion beam ...

Energy Technology Data Exchange (ETDEWEB)

During rolling contact fatigue of the inner rings of ball bearings three stages of material response can be distinguished, in terms of the volume that is plastically deformed upon overrolling. After a first stage of material strengthening during which a decrease occurs for the volume that is deformed plastically, an effectively stationary, second stage is entered which is eventually succeeded by a third stage exhibiting a pronounced increase of the volume that is deformed plastically upon overrolling, which leads to failure. It is suggested that carbon diffusion induced by local temperature peaks occurring at the moment of overrolling is the key mechanism leading to fatigue damage. The amount of decomposed retained austenite is a useful, practical parameter to assess fatigue life. It is shown that published ideas about the role of certain components of residual stress in enhancing fatigue life are not correct and that the so-called ...

International Nuclear Information System (INIS)

Total-dose irradiation seriously damages MOS devices and their circuit performance. Threshold voltage shifts, transconductance degradation and increase in off-state leakage current are generally observed for irradiated devices. These instabilities are essentially due to positive and/or negative charge trapping in SiO_2 and interface trap generation at the SiO_2/Si interface. Radiation hardening of CMOS VLSIs is to eliminate these trapping effects, and for this purpose, special considerations for fabrication processes and layout design are necessary. In this paper, basic mechanisms for radiation-induced charge trapping and related effects on MOS devices are reviewed. Also discussed are radiation-hardening technologies from both fabrication-process and layout-design viewpoints. Using these technologies, 1 #mu#m radiation-hard CMOS gate arrays have been successfully developed. Experimental data taken for 2k-gate test chips indicate that radiation ...

International Nuclear Information System (INIS)

Ethidium bromide (EB) and ultraviolet light (UV) in combination are known to produce a synergistic induction of 'petite' mutants in yeast. Two other agents were combined with EB, 3-Carbethoxypsoralene (3 CPs) activated by 365 nm light or #gamma# rays. EB in combination with 3 CPs also resulted in an enhanced production of 'petite' mutants. After the photoaddition of 3 CPs in exponential phase cells, recovery of the 'petite' mutation during dark liquid holding was inhibited by the presence of EB producing an enhanced number of 'petite' mutants. The behavior of mitochondrial antibiotic resistance markers after individual and combined treatments with EB and 3 CPs indicates a random loss of markers after EB and a preferential loss of a certain region for the 3 CPs photoaddition. The combination of the two agents leads to an additivity of total drug marker losses rather than a synergistic loss. The combination of EB with #gamma# rays produced no enhancement in 'petite' induction. A ...

Science.gov (United States)

The goal of the present study is to elucidate the effect of lipid domain formation on activities of Naja naja atra and Bungarus multicinctus phospholipase A(2) (PLA(2)) enzymes. Sphingomyelin inhibited enzymatic activity and membrane-damaging activity of PLA(2) against egg yolk phosphatidylcholine (EYPC), while cholesterol and cholesterol sulfate abrogated the inhibitory effect of sphingomyelin. The ability of cholesterol and cholesterol sulfate to abolish the inhibitory effect of sphingomyelin was closely related to their capacity to induce domain formation in EYPC/sphingomyelin vesicles. Laurdan fluorescence measurement revealed that membrane packing of EYPC/sphingomyelin vesicles was differently affected by cholesterol and cholesterol sulfate. Unlike cholesterol, cholesterol sulfate was unable to promote domain formation in dipalmitoylphosphatidylcholine (DPPC) vesicles. Cholesterol increased but cholesterol sulfate reduced PLA(2) activity ...

Energy Technology Data Exchange (ETDEWEB)

The plastic displacements around Knoop indentations made in hard titanium/aluminum multilayered films on soft aluminum alloy substrates have been studied. Indentations were cross-sectioned and imaged using the focused-ion-beam (FIB) milling and high-resolution scanning electron microscopy (SEM), respectively. The FIB milling method has the advantage of removing material in a localized region without producing mechanical damage to the specimen. The micrographs of the cross-sectioned indentations indicate that most of the plastic deformation around the indentation is dominated by the soft aluminum substrate. There is a very small change in the multilayered film thickness around the indentation{emdash}less than 10{percent}. The plastic deformation of the thin film resembles a membrane being deflected by a localized pressure gradient across the membrane. Stress-induced voids are also observed in the multilayered film, especially in the area around ...

Energy Technology Data Exchange (ETDEWEB)

A fractographic and numerical approach is presented to analyze hydrogen-plasticity interactions in pearlitic steel and to elucidate the main hydrogen transport mechanism in this material under triaxial stress states produced by notches. Fractographic analysis showed that the microdamage produced by the hydrogen was clearly detectable by scanning electron microscopy (SEM), through a specific microscopic topography associated with hydrogen effects (tearing topography surface or TTS). Numerical computations obtained by using an elastic-plastic finite element program gave the progressive spreading of the plastic zone, closely associated with the movement of dislocations. In the majority of cases, the plastic zone (PZ) clearly exceeds the hydrogen affected region (TTS) and has no relation with it. In some tests, however, the hydrogen-induced micro-damage surpasses the only region in which there is dislocation movement, and in this case the net ...

Energy Technology Data Exchange (ETDEWEB)

For an assessment of the future US spallation neutron source (SNS) target performance, radiation induced hardening and microstructural evolution were investigated as a function of ion dose for EC316LN stainless steel. Irradiation was carried out using 3.5 MeV Fe{sup +}, 360 keV He{sup +}, and 180 keV H{sup +} simultaneous ion-beams at 200 deg. C to simulate the damage, He and H production in the SNS target vessel wall. At low dose (< 1 dpa), the predominant defects were black dots whose number density saturated rapidly within a few dpa. This was followed by the evolution of interstitial loops whose number density saturated below 15 dpa. Although He-bubbles were not visible, severely scalloped loops suggested that the implanted He/H atoms existed in the form of small clusters. Comparison with reported neutron irradiation data showed that hardening and ductility loss occurred mostly in the black dot regime (< 1 dpa), but that good ...

Energy Technology Data Exchange (ETDEWEB)

This paper overviews the general features of computer program 'HEC-5, Simulation of Flood Control and Conservation Systems', with emphasis on the capabilities of the most recent release of HEC-5, Version 7.2, dated March 1991. HEC-5 can simulate the essential features and operation goals and constraints of simple or complex systems with simulation intervals ranging from minutes to one month. Single event flood analysis and period of record conservation analysis may be accomplished with the model. Flood control analysis includes balanced system operation for downstream damage centers with consideration of forecasted local flows and hydrologic routing. In addition, induced surcharge operation based on spillway gate regulation schedules can be simulated. Hydropower analysis may include run-of-river, peaking, and pumped storage plants as well as system power operation. Water supply simulation can include reservoir and downstream ...

Energy Technology Data Exchange (ETDEWEB)

Aluminum nitride has been proposed as electrically insulating coating in connection with blankets made of vanadium alloys. Irradiations were performed with an applied DC electric field of 100 kV/m, using a 104 MeV {alpha}-particle beam. The dose achieved were 0.1 dpa at 300 C, 0.05 dpa at 400 C, and 0.06 dpa at 500 C. The out-of-beam conductivity {sigma}{sub 0} decreased at all temperatures employed during early stage of irradiation. Before 0.02 dpa had been reached, {sigma}{sub 0} dropped to low values of typically (2-4) x 10{sup -11} ({Omega} m){sup -1}. Although a moderate increase can be observed during further irradiation, {sigma}{sub 0} remained below the initial value of the unirradiated specimen for all temperatures. That is, there is no significant evidence for radiation induced electrical degradation. The in-beam conductivity {sigma}, measured continuously during irradiation, also decreased by at least one order of magnitude. Relevant ...

Energy Technology Data Exchange (ETDEWEB)

Tensile specimens of the normalized and tempered fully martensitic steel DIN 1.4914 were helium implanted up to 340 appm within the temperature range 300-720/sup 0/C using a 104 MeV alpha particle beam. The high He/damage ratio of 1850 appm He/dpa allowed to determine the effect of helium on material properties. After irradiation tensile strength and ductility were investigated mainly at test temperatures equal to the irradiation temperatures. While short time irradiations with helium contents up to 100 appm have shown no visible effect on the tensile behaviour at all temperatures investigated, long time irradiations reduced the material strength at irradiation temperatures above about 440/sup 0/C. This irradiation induced softening obscured the predicted minor hardening effect of the observed He-bubbles completely and increases with irradiation time and temperature. The fracture mode of helium-implanted and control specimens is found to remain ...

Science.gov (United States)

Current antidotal regimens for organophosphorus compound (OP) poisoning consist of a combination of pretreatment with a spontaneously reactivating AChE inhibitor such as pyridostigmine bromide, and postexposure therapy with anticholinergic drugs such as atropine sulfate and oximes such as 2-PAM chloride (Gray, 1984). Although these antidotal regimens are effective in preventing lethality of animals from OP poisoning, they do not prevent postexposure incapacitation, convulsions, performance deficits, or, in many cases, permanent brain damage (Dunn and Sidell, 1989). These problems stimulated the development of enzyme bioscavengers as a pretreatment to sequester highly toxic OPs before they reach their physiological targets. Several studies over the last two decades have demonstrated that exogenously administered human serum butyrylcholinesterase (Hu BChE) can be used successfully as a safe, efficacious, and single prophylactic treatment to counteract the toxicity of ...

International Nuclear Information System (INIS)

Exposure of cells to light of less than 320 nanometers wavelengths may lead to lethal lesions and perhaps carcinogenesis. Many organisms have evolved mechanisms to repair U.V. light-induced damage. Organisms such as deep-sea bacteria are presumably never exposed to U.V. light and perhaps occasionally to visible from bioluminescence. Thus, the repair of U.V. damage in deep-sea bacterial DNA might be inefficient and repair by photoreactivation unlikely. The bacteria utilized in this investigation are temperature sensitive and barophilic. Four deep-sea isolates were chosen for this study: PE-36 from 3584 m, CNPT-3 from 5782 m, HS-34 from 5682 m, and MT-41 from 10,476 m, all are from the North Pacific ocean. The deep-sea extends from 1100 m to depths greater than 7000 m. It is a region of relatively uniform conditions. The temperature ranges from 5 to -1"0C. There is no solar light in the deep-sea. Deep-sea bacteria are ...

International Nuclear Information System (INIS)

Space particles act on semiconductor devices by creating charges (electrons, holes) in the silicon and the silicon dioxide, and by creating displacement damage. These primary phenomena alter the electrical parameters of MOS and bipolar devices (threshold voltage V_t, mobility #mu#, conductivity #sigma#, current gain #beta#). The dose rate is not important in space (a few rad (Si)/h) but as the durations of space expeditions are on average from seven to twelve years, the total dose is an aggravating factor in the behaviour of the electrical parameters and also in device operation. The total dose effect from the beginning of charge creation (ionization) to the parameter shifts is reviewed. One can note that this effect is permanent because there will almost always be charge creation in space. Another important phenomenon is called the Single Event Upset (S.E.U.) and caused by the heavy ions and the protons which come from the galactic rays. The consequence of S.E.U. ...

International Nuclear Information System (INIS)

The radiation-induced microstructural changes have been studied by cross-sectional transmission electron microscopy for single-crystal #alpha#-Al_2O_3 samples irradiated with triple ion beams (0.25 MeV H"+, 0.6 MeV He"+ and 2.4 MeV O"2"+; 'Triple (A)'), (0.33 MeV H"+, 0.45 MeV He"+ and 1.3 MeV O"+; 'Triple (B)') and three consecutive single ion beams (0.3 MeV H"+ ion followed by 0.6 MeV He"+ and then 0.8 MeV O"+ ions) at 650 C to doses in the range 0.1-8.4 dpa at the damage peak. In the specimen irradiated with Triple (A), having the same average projected range to a total peak dose of 3.7 dpa, cavities with an average diameter of 13 nm were formed between 1.2 and 1.75 #mu#m in depth causing a swelling of 0.1% at the peak, which is larger than those of the specimens irradiated with other conditions. The extent of the cavity-introduced region is some 40% smaller than observed in the damage region due to the He"+ and the O"+ ...

Energy Technology Data Exchange (ETDEWEB)

Detecting a camouflaged target in a visually noisy background depends on the ability of the observer to discriminate the target from the surrounding terrain. Visible laser irradiation at less than damage levels can act as a masking source by compromising or reducing the observer's ability to resolve differences in the visual scene. Previous research has examined this concept by investigating laser flash effects on: acuity (size discrimination); tracking (motion discrimination); visual sensitivity (color); and contrast sensitivity functions (luminance contrast). In all cases, flashes from continuous-wave (CW) sources have proven more effective visually than pulsed (Q-switched) sources, when compared on peak-energy criteria (i.e., MPE), even though Q-switched lasers induce damage at lower energy doses. Additionally, the inherent safety of ultra-short laser pulses has been questioned. Past animal research has shown ...

International Nuclear Information System (INIS)

In view of the anticipated increased use of atomic energy in industry, the possible long-term effects of chronic radiation exposure were studied in five generations of rats. Female rats (F_0) were given tritiated drinking water ("3HOH;3#mu#Ci/ml) from adolescence (60 days) until and throughout pregnancy. A separate study showed that the maximum radioactivity in the urine is reached in 30 days, and in the blood in 42 days. In the newborns, the highest specific activity was in the nucleic acid fraction, but total radioactivity was mainly due to the water (body fluids) compartment. No signs of radiation illness or increase in cataract formation in the mothers were observed. The food and water intake and body weight changes before pregnancy were normal. The course and the outcome of pregnancy were also normal. However, 60% of the newborns (F_1) exhibited hematomas, edemas, and subdural hemorrhages, which disappeared at 30 days of age. Bollod analysis of the F_1 offspring at various ages ...

International Nuclear Information System (INIS)

Olfactory tract has been demonstrated to be an important portal for inhaled solid nanoparticle transportation into the central nervous system (CNS). We have previously demonstrated that intranasally instilled Fe_2O_3 nanoparticles could transport into the CNS via olfactory pathway. In this study, we investigated the neurotoxicity and size effect of repeatedly low-dose (130 #mu#g) intranasal exposure of nano- and submicron-sized Fe_2O_3 particles (21 nm and 280 nm) to mice. The biomarkers of oxidative stress, activity of nitric oxide synthases and release of monoamine neurotransmitter in the brain were studied. Our results showed that significant oxidative stress was induced by the two sizes of Fe_2O_3 particles. The activities of GSH-Px, Cu,Zn-SOD, and cNOS significantly elevated and the total GSH and GSH/GSSG ratio significantly decreased in the olfactory bulb and hippocampus after the nano- and submicron-sized Fe_2O_3 particle treatment (p < 0.05). The ...

KoreaScience (Korea)

Full Text Available

International Nuclear Information System (INIS)

The author furnishes a review of incidents of major damage to high-output steam turbines. At the same time, he thereby underlines the call for an improvement in the exchange of experience on such damage and its causes at international level. Only the careful observance of past damage experience - including that of foreign manufacturers and operators - complete and modern monitoring equipment and the painstaking evaluation of all data furnished by such equipment can keep the risk of new technical development within economically tolerable limits. (orig.).

KoreaScience (Korea)

Full Text Available

KoreaScience (Korea)

Full Text Available

KoreaScience (Korea)

Full Text Available

KoreaScience (Korea)

Full Text Available

International Nuclear Information System (INIS)

GRR-1 is a 5MW open pool type research reactor with MTR-type fuel elements cooled and moderated by light water with beryllium reflectors at the two opposing sides of the core. A graphite thermal neutron column is adjusted to one side of the core. Six radial horizontal beam tubes are available, of which three contain in-pile collimators for neutron scattering instruments. The reactor is currently out of operation for inspection and refurbishment purposes. The core has been dismantled and the fuel elements are stored in the used fuel storage tank. The GRR-1 inspection and refurbishment plan involves inspection and eventually replacement of the reactor's primary cooling circuit. The health physics procedures to be implemented during inspection of the main water outlet are divided in three stages: a) pool dose rate survey from pool top, b) pool drainage by decreasing water level in steps and c) inspection of the water main outlet. urpose of the present work is the evaluation of the ...

Energy Technology Data Exchange (ETDEWEB)

The Nuclear Regulatory Commission (NRC) has sponsored several studies to identify and quantify, through the use of models, the potential health effects of accidental releases of radionuclides from nuclear power plants. The Reactor Safety Study provided the basis for most of the earlier estimates related to these health effects. Subsequent efforts by NRC-supported groups resulted in improved health effects models that were published in the report entitled {open_quotes}Health Effects Models for Nuclear Power Plant Consequence Analysis{close_quotes}, NUREG/CR-4214, 1985 and revised further in the 1989 report NUREG/CR-4214, Rev. 1, Part 2. The health effects models presented in the 1989 NUREG/CR-4214 report were developed for exposure to low-linear energy transfer (LET) (beta and gamma) radiation based on the best scientific information available at that time. Since the 1989 report was published, two addenda to that report have been prepared to (1) ...

Energy Technology Data Exchange (ETDEWEB)

This work evaluated the effect of gamma radiation on reducing the population of Staphylococcus aureus, Escherichia coli nd Salmonella typhimurium in ground chicken breast stored under refrigeration. The experiment included a control and 4 doses of gamma radiation ( 2.0, 4.0, 6.0 and 8.0 kGy) along with 5 periods of storage under refrigeration ( 1, 7 14, 21 and 28 days). Samples of ground chicken breast were inoculated with Staphylococcus aureus (ATCC 14458), Escherichia coli (ATCC 11105) and Salmonella typhimurium (ATCC 0626), irradiated at temperatures between 4 and 8 deg C and stored under refrigeration (5 deg C) for 28 days. The increased radiation dose and period of storage under refrigeration caused a reduction of Staphylococcus aureus, Escherichia coli and Salmonella typhimurium populations in the ground chicken breast. Mean radiation D values determined for Staphylococcus aureus and Escherichia ...

International Nuclear Information System (INIS)

This present study evaluated the effect of gamma radiation on the fungal survival in packed medicinal plants, purchased from wholesale and retail market, in different period (0 and 30 days) after the treatment. Five kind of medicinal plants (Peumus boldus, Camellia sinensis, Maytenus ilicifolia, Paullinia cupana and Cassia angustifolia), were collected from different cities of Sao Paulo State, and submitted to irradiation treatment using a 60Co source (type Gammacell 220) with doses of 5,0 kGy and 10 kGy and at dose rate of 3.0 kGy/h. Non-irradiated samples (control group) were used for fungal counts and serial dilutions from 10-1 to 10-6 of the samples were seeded in duplicates and plated using the surface culture method in Dichloran 18% Glycerol Agar (DG 18) and were counted after five days at 25 deg C. The control group revealed the presence of genera Aspergillus and Penicillium, which are known as toxigenic fungi and a few samples of ...

International Nuclear Information System (INIS)

Radiation technology offers a very wide scope for utilisation and commercial exploitation in various field. All over the world, this technology is being favourably considered for different applications like radiation sterilisation of medical products, preservation of food by controlling the physiological processes for extending shelf-life and eradication of microbial and insect pests, radiation processing of polymeric materials and treatment of sewage sludge. Bangladesh Atomic Energy Commission has taken radiation processing programmes in a big way right from its inception. This paper describes the studies carried out by various research groups in Bangladesh Atomic Energy Commission mainly using Cobalt-60 gamma radiation. The investigation covers medical sterilisation, food preservation and development and modification of polymeric materials by gamma radiation. Both food preservation and radiation ...

International Nuclear Information System (INIS)

As part of a study into the properties of ferroelectric single crystals at nanoscale dimensions, the effects that focused ion beam (FIB) processing can have, in terms of structural damage and ion implantation, on perovskite oxide materials has been examined, and a post-processing procedure developed to remove such effects. Single crystal material of the perovskite ferroelectric barium titanate (BaTiO_3) has been patterned into thin film lamellae structures using a FIB microscope. Previous work had shown that FIB patterning induced gallium impregnation and associated creation of amorphous layers in a surface region of the single crystal material some 20 nm thick, but that both recrystallization and expulsion of gallium could be achieved through thermal annealing in air. Here we confirm this observation, but find that thermally induced gallium expulsion is associated with the formation of gallium-rich platelets on the surface ...

Energy Technology Data Exchange (ETDEWEB)

This report describes the basis, results, and related risk implications of an analysis performed by an ad hoc working group of the U.S. Nuclear Regulatory Commission (NRC) to assess the containment bypass potential attributable to steam generator tube rupture (SGTR) induced by severe accident conditions. The SGTR Severe Accident Working Group, comprised of staff members from the NRC`s Offices of Nuclear Reactor Regulation (NRR) and Nuclear Regulatory Research (RES), undertook the analysis beginning in December 1995 to support a proposed steam generator integrity rule. The work drew upon previous risk and thermal-hydraulic analyses of core damage sequences, with a focus on the Surry plant as a representative example. This analysis yielded new results, however, derived by predicting thermal-hydraulic conditions of selected severe accident scenarios using the SCDAP/RELAP5 computer code, flawed tube failure modeling, and tube failure probability ...

Energy Technology Data Exchange (ETDEWEB)

Peroxisome proliferating agents (PPAs) are a structurally diverse group of chemicals that include environmental chemical contaminants such as certain chlorinated herbicides, solvents and plasticizers. PPAs have previously been shown to induce anti-trout laruci acid hydroxylase immunoreactive proteins in bluegill and catfish. In this investigation, induction of lauric acid hydroxylase activity and immunoreactive proteins was confirmed, and the mass spectral analysis of specific hydroxylation products was performed in order to identify possible species-specific differences in fatty acid metabolism. Male bluegill (Lepomis macrochirus) and channel catfish (Ictalurus punctatus) were administered clofibrate or ciprofibrate 48 hr prior to hepatic or trunk kidney (catfish only) microsome preparation. While no significant differences were observed in male catfish, male bluegill had significant decreases in hematocrit and plasma protein indicating hemodilution due to ...

International Nuclear Information System (INIS)

The present study was designed to assess the radioprotective effects of amifostine on ovarian follicles. Three week-old female mice with or without pretreatment of amifostine were irradiated with 6.42 Gy of #gamma# -ray. Ovaries were collected 0 and 6h after irradiation. DNA fragmentation pattern and expression of genes and activity of proteins related with apoptosis were investigated by means of RT-PCR and Western blot. Proliferation of granulosa cells was reduced and incidence rate of follicular atresia was increased in ovarian follicles in #gamma# -ray irradiated mice compared to those in control or amifostine-treated group. DNA fragmentation was increased in time-dependent manner in granulosa cells of all irradiated groups. However, no difference between amifostine pre-treated group and irradiated groups was found and the expression of p53 as tumor suppressor gene and Bax as one of pro-apoptotic Bcl-2 family was increased in irradiated mice ovaries. PARP as DNA ...

British Library Electronic Table of Contents (United Kingdom)

The marine environment is becoming increasingly contaminated by environmental pollutants with the potential to damage DNA, with marine sediments acting as a sink for many of these contaminants. Understanding genotoxic responses in sediment-dwelling marine organisms, such as polychaetes, is therefore of increasing importance. This study is an exploration of species-specific and cell-specific differences in cell sensitivities to DNA-damaging agents in polychaete worms, aimed at increasing fundamental knowledge of their responses to genotoxic damage. The sensitivities of coelomocytes from three polychaetes species of high ecological relevance, i.e. the lugworm Arenicola marina, the harbour ragworm Nereis diversicolor and the king ragworm Nereis virens to genotoxic damage are compared, and dif...

Science.gov (United States)

Treatment Induced Hypertension

Energy Technology Data Exchange (ETDEWEB)

ExternE is a pan{sub E}uropean project aimed at identifying and quantifying external effects from different energy production technologies around Europe. The Swedish implementation carried out case studies on a biomass plant, a coal plant and a hydro power plant. The conventional approach within the ExternE project is to estimate impacts for each priority pathway associated with the fuel cycle, and then economic methods to obtain estimates for the economic damage of each particular impact pathway. However, in the case of hydro power, it is generally not possible to estimate the most important impacts quantitatively. Therefore, a contingent valuation (CV) study was initiated. In a typical CV-study, a selection of individuals are asked to state their willingness to pay for a certain environmental improvement or to avoid an environmental damage. Welfare economic theory suggests that the well-being effects on people from a change from one situation ...

Energy Technology Data Exchange (ETDEWEB)

The regular occurrence of large-scale earthquakes in Japan necessitates the use of earthquake disaster prevention systems that focus on gathering damage information on gas supply facilities immediately after an earthquake strikes and minimizing the damage. This paper discussed the development of an earthquake damage estimation system for city gas pipelines that can show damage information in real-time by using earthquake records obtained from densely deployed earthquake observation networks and the most advanced telecommunication and information technologies. The paper summarized the earthquake damage estimation system (EDES) and Toho Gas disaster prevention measures. Specific topics that were discussed included the Toho Gas supply method; earthquake countermeasures; construction of computer systems; normal and emergency operation of EDES; and verification of functions in actual ...

UK PubMed Central (United Kingdom)

Because copper catalyzes the conversion of H₂O₂ to hydroxyl radicals in vitro, it has been proposed that oxidative DNA damage may be an important component of copper toxicity....Full Text Available

Energy Technology Data Exchange (ETDEWEB)

This book contains over 20 selections. Some of the titles are: Continuum damage mechanics studies on the dynamic fracture of concrete; Dynamic compressive strength of cementitious materials; Rate-sensitivity of mode I and mode II fracture concrete; and An impact damage model of concrete.

International Nuclear Information System (INIS)

The annealing behavior of the radiation damage in epitaxial Pd_2Si and NiSi_2 films on Si, due to the implantation of 100 keV Ar ions, is investigated by using the channeling technique with "4He ions. (U.K.).

Energy Technology Data Exchange (ETDEWEB)

This paper is concerned with the validation of the 3D deterministic neutral-particle transport theory code EVENT for shielding applications. The code is based on the finite element-spherical harmonics (FE-P{sub N}) method which has been extensively developed over the last decade. A general multi-group, anisotropic scattering formalism enables the code to address realistic steady state and time dependent, multi-dimensional coupled neutron/gamma radiation transport problems involving high scattering and deep penetration alike. The powerful geometrical flexibility and competitive computational effort makes the code an attractive tool for shielding applications. In recognition of this, EVENT is currently in the process of being adopted by the UK nuclear industry. The theory behind EVENT is described and its numerical implementation is outlined. Numerical results obtained by the code are compared with predictions of the Monte Carlo code MCBEND and ...

Energy Technology Data Exchange (ETDEWEB)

Neutron and gamma ray energy spectra were measured using an NE-213 scintillator at depths of 7.2, 15.2, and 22.2 cm in a tissue-equivalent phantom which was uniformly irradiated on one face by deuterium--tritium (DT) neutrons. Coupled neutron--gamma ray multigroup discrete-ordinates calculations were performed using semi-infinite slab geometry. These calculations were used to supplement the measured spectra below 1 MeV. Similar calculations were performed to study the perturbation in the phantom due to the detector. The measured and calculated spectra were used to determine the kerma distributions for neutrons and gamma rays at each location. The gamma radiation was determined to contribute more than 10% of the total dose at each depth. The calculated kerma also reveals that a knowledge of the gamma ray spectra below 1 MeV is desirable. Key words: neutron--gamma spectra, spectrometry, kerma distributions, coupled multigroup calculations

International Nuclear Information System (INIS)

The simultaneous effects of irradiating full grown pupae of Spodoptera Littoralis with doses 30 and 40 krad followed by topical treatment of adults with methomyl were studied. Gamma rays decreased the toxicity of methomyl against adult moths. The obtained LD_5_0 values for male moths emerging from unirradiated or irradiated pupae with 30 or 40 krad were 7, 9.93 and 10.33 u g/g. b.wt., respectively. F1 larvae (produced from unirradiated females mated to irradiated males) became more tolerant to methomyl by increasing radiation doses from 5 to 30 krad. The toxicity of methomyl to F1, F2 and F3 larvae (whose male parents had been irradiated in the pupal stage with 10 krad) was less than its toxicity to the larvae produced from unirradiated parents. F2 and F3 larvae were more tolerant to methomyl effect than the F1 larvae.

Energy Technology Data Exchange (ETDEWEB)

The primary E1, M1 and E2 ..gamma..-radiation in /sup 87,88,89/Sr observed after thermal neutron capture was compared with the predictions of single particle and giant resonance models. The nuclei feature a wide range of neutron binding energies between 6.3 and 11.1 MeV, which makes a 5.5 MeV spectrum of primary transition energies available for investigation. The (n, ..gamma..) reaction was used to estimate the parameters of the spin-flip M1 giant resonance in strontium. The total energy weighted M1 strength of this resonance exceeds the results of shell model and random phase approximation calculations for /sup 90/Zr by a factor of 3-4. The E1 strengths were found to agree with the established giant dipole resonance model. The few data on primary E2 transitions do not allow to differentiate between the giant quadrupole resonance and the single particle models.

Energy Technology Data Exchange (ETDEWEB)

Food irradiation is the processing of food products by ionizing radiation in order, among other things, to control food borne pathogens, reduce microbial load and insect infestation, inhibit the germination of root crops, and extend the durable life of perishable products. Irradiation of dried food ingredients, particularly herbs and spices, has a great application potential, and has already been implemented in many countries. Spice irradiation is performed to increase the hygienic quality and used as decontamination processes instead of fumigation methods. European Community approves irradiation processing as an effective residue-free alternative. The present paper evaluates the effect of ionizing radiation on sensorial properties of cinnamon (Laurus cinnamomum) and nut meg (Myristica fragans). The samples have been irradiated in multipurpose irradiator of {sup 60}Co in the doses: 0, 5, 10, 15, 20 e 25 kGy. (author)

International Nuclear Information System (INIS)

recycling of waste polypropylene (WPP) and waste rubber (WR) originated from rejected worn-out tires present very important problem due to their huge amount and their negative impact on environment. many communities in the world are struggling with this problem of how to manage waste disposal, in order to eliminate or reduce waste rubber from the environment and to reduce costs of some rubber and polypropylene articles. trials to reuse waste rubber and waste polypropylene, have encountered some difficulties.such two substrate polymers differ from each other in nature, since waste polypropylene is thermoplastic while waste rubber exists in thermosetting state. accordingly, the study and use of their mixtures should be very interesting.the aim of this work is to modify the physical and chemical properties of WR and WPP each in the form of powder (120,80 mech size), through a trial to graft some vinyl comonomers onto their surfaces using gamma ...

International Nuclear Information System (INIS)

Instrumental neutron activation analysis (INAA) and radionuclide X-ray fluorescence analysis (RXFA) were used for the determination of rare earth elements. For INAA, solution obtained by sample decomposition was dripped onto filter paper, enclosed and sealed into a polyethylene foil. The sample was activated in reactor WWR-S over a period of 4 to 6 hours with a neutron fluence of 10"1"3cm"-"2. Gamma radiation measurement was carried out with a planar and a coaxial HP-Ge detector in three decay periods. La, Ce, Nd, Sm, Eu, Gd, Tb, Ho, Tm, Yb and Lu were determined. The advantage of the method is its accuracy and high sensitivity, the disadvantage is the time-consuming analysis. The RXFA method was used as a rapid and operative method for the analysis of loose ore samples, aqueous and organic solutions of rare earth elements. For exciting X-ray radiation, "2"4"1Am was used and the radiation of K-lines was detected with a planar Si(Li) detector. ...

Energy Technology Data Exchange (ETDEWEB)

Selected local woods and their wood-polymer combinations or composites (WPC) were tested for their thermal conductivity and their fire resistance. WPC were prepared by polymerizing monomers ''in situ'' in oven dried woods by gamma radiation. The monomers included acrylonitrile (AN), 60% styrene-40% acrylonitrile (STAN), methyl methacrylate (MMA), 95% methyl methacrylate-5% dioxane (MD), and vinylidene chloride (VDC). A reduction in thermal conductivity was exhibited by all the composites prepared. W-PAN showed the greatest reduction in thermal conductivity and W-PSTAN in general showed the least. An explanation is suggested for this behaviour. The polymers PMMA and PMD were found to enhance flammability of the woods while PVDC, PAN, and PSTAN imparted fire resistance to the woods. Of the six local woods studied, Ramin-and-Keruing-polymer composites showed the highest flammable tendencies obtained. The ...

International Nuclear Information System (INIS)

Radiation-and-thermal-combined degradation of some kinds of cable insulating and jacketing materials was evaluated by accelerated aging tests. Plasticized polyvinyl chloride (PVC), silicone rubber, crosslinked and non-crosslinked halogen-free flame-retardant polyolefins (NH-XLPO and NH-PO) and ethylene-propylene rubber (EP rubber) of experimental formulation were degraded at accelerated rates, that are 50-1000 times the degradation rate under standard conditions (e.g.; 1Gy/h, 50degC), and a method to assess the lifetime of these materials under standard conditions was studied. The degradation was investigated by measuring tensile properties. In the accelerated aging tests, rates of elongation decrease owing to degradation for these materials were in proportion to the increase in accelerated rate. The PVC lifetime estimated from sequential aging tests had a tendency to extend beyond that from simultaneous aging tests, while the lifetime of other materials estimated from both aging tests ...

Energy Technology Data Exchange (ETDEWEB)

Natural radioactive materials under certain conditions can reach hazardous radiological levels. The natural radionuclide ({sup 238}U, {sup 232}Th, {sup 40}K) contents of rock samples at various locations in the North Tushki area were investigated using gamma-spectrometric analysis. Estimates of the measured radionuclide content have been made for the absorbed dose rate of gamma radiation. The equivalent radium (R{sub eq}) and the external hazard index (H{sub ex}) which resulted from the natural radionuclides in soil are also calculated and tabulated. The studied samples have been collected from various rock exposures in the North Tushki area. The distribution of major oxides, U and Th were studied. It is found that the enrichment and depletion of the major oxides are mainly due to the effect of hydrothermal alteration, which caused mobility of some major oxides, which increases some elements and decreases others. It is important to mention that ...

International Nuclear Information System (INIS)

The underground storage tanks at the Hanford Complex contain mixed wastes generated over many years from plutonium production and recovery processes. The chemical changes of the organic materials used in the extraction processes and disposed to the tanks have a direct bearing on several specific safety issues, including potential energy releases from these tanks. This paper will give details of a study that is directed towards elucidating thermal and radiological decomposition mechanisms and products of the organic contents of the tanks. The study is being conducted in two parts. The first part, an aging study, will determine kinetics and products of the degradation of a simulated waste subjected to #gamma#-radiation from an external source. Although the simulant will not contain radioactive elements, it will contain other representative inorganic compounds and the primary organic compounds thought to have been disposed to the tanks. The second part of the ...

Energy Technology Data Exchange (ETDEWEB)

Marketing of minimally processed vegetables (MPV) are gaining impetus due to its convenience, freshness and apparent health effect. However, minimal processing does not reduce pathogenic microorganisms to safe levels. Food irradiation is used to extend the shelf life and to inactivate food-borne pathogens. In combination with minimal processing it could improve safety and quality of MPV. A microbiological screening method based on the use of direct epifluorescent filter technique (DEFT) and aerobic plate count (APC) has been established for the detection of irradiated foodstuffs. The aim of this study was to evaluate the applicability of this technique in detecting MPV irradiation. Samples from retail markets were irradiated with 0.5 and 1.0 kGy using a {sup 60}Co facility. In general, with a dose increment, DEFT counts remained similar independent of the irradiation while APC counts decreased gradually. The difference of the two counts gradually increased with dose increment in all ...

International Nuclear Information System (INIS)

... 1343-3563 v. 57(1) SPECIFIC NUCLEAR REACTORS AND ASSOCIATED

KoreaScience (Korea)

Full Text Available

KoreaScience (Korea)

Full Text Available

Energy Technology Data Exchange (ETDEWEB)

In order to investigate the influence of grain boundary cavities on the life time of Alloy 800 H various fatigue tests have been performed at 800/sup 0/C. Cavity formation has been observed only in asymmetrical tests. Compared to the corresponding symmetrical tests, the cyclic life time is shorter. As the cavitation damage increases, the ratio of life times in vacuum and in air steadily decreases from an initial value of 5. In extreme cases it can reach a value close to 1. In this case, cavitation damage dominates over the usual damage mechanism, which is cracks from the surface.

Science.gov (United States)

... Abstract : High temperature testing of graphite/epoxy laminates and composite sandwich panels was performed while the Shuttle was on orbit to ...

Science.gov (United States)

... storm. There was little damage to high-voltage transmission lines and communication towers in northern New England. ...

International Nuclear Information System (INIS)

In the third millennium, when the main words are globalization, world net of computers, genetic code and efficiency, deep transformations have been incorporated to human behavior. Among such transformations it may be pointed out, matching with the objectives of this study, the modem consumer's profile. The consumers have quickly become more and more conscious and demanding regarding to the quality of the available products in the market. In that sense, the consumer's concern about the natural and healthy appearance, as well as the preservation of the nutritious content of the foods, have been a constant sign of alert for producers and suppliers. Besides, the timeless for domestic preparation of foods have imposed the use of minimally processed as an incontestable reality. A barrier for the production of minimally processed foods is imposed by the degree of perishability of certain products, such as the cassava-parsley. This vegetable is a source of energy, calcium, phosphorus and ...

Energy Technology Data Exchange (ETDEWEB)

External radiation dose exceeded 5,000 rad in three cases, and intravaginal radiation dose was 5,000 rad in one case. Radiation damage including perforation was seen in the end of ileus in one case, in the sigmoid and rectum in two cases, and in the end of ileus, sigmoid and rectum in the last case. Satisfactory results were obtained by the removal of the ileocecum in the case of the damage in the end of the ileus. However, only colostomy was performed for the damage in the sigmoid and rectum.