gambiense sleeping sickness: Topics by WorldWideScience.org

Neuroinflammation and brain infections: Historical context and current perspectives

BackgroundTrypanosomosis is a major impediment to livestock farming in sub-Saharan Africa and limits the full potential of agricultural development in the 36 countries where it is...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

An overview of current concepts on neuroinflammation and on the dialogue between neurons and non-neuronal cells in three important infections of the central nervous systems (rabies, cerebral malaria, and human African trypanosomiasis or sleeping sickness) is here presented. Large numbers of cases affected by these diseases are currently reported. In the context of an issue dedicated to Camillo Golgi, historical notes on seminal discoveries on these diseases are also presented. Neuroinflammation is currently closely associated with pathogenetic mechanisms of chronic neurodegenerative diseases. Neuroinflammatory signaling in brain infections is instead relatively neglected in the neuroscience community, despite the fact that the above infections provide paradigmatic examples of alterations o...

2011-01-01

Respiratory Sleep Physiology

KoreaScience (Korea)

Full Text Available

2009-06-01

Unearthing the Phylogenetic Roots of Sleep

The relationship between the rate of melatonin excretion and sleep consolidation for locomotive engineers in natural sleep settings

Why we sleep remains one of the enduring unanswered questions in biology. At its core, sleep can be defined behaviorally as a homeostatically regulated state of reduced movement and sensory...Full Text Available

2008-08-05

Sleep Onset Period from the EEG Point of View

BackgroundThe aim of the study was to examine the role that melatonin production plays in the regulation of sleep consolidation in a population of shiftworkers working and sleeping...Full Text Available

KoreaScience (Korea)

Full Text Available

2009-06-01

Memory Before and After Sleep in Patients with Moderate Obstructive Sleep Apnea

Transposons for cancer gene discovery: Sleeping Beauty and beyond

Objective:The aim of this study was to investigate the effects of obstructive sleep apnea (OSA) on procedural and declarative memory encoding in the evening prior to sleep, on memory...Full Text Available

2009-12-15

REM Sleep Behavior Disorder in Patients With Guadeloupean Parkinsonism, a Tauopathy

The use of Sleeping Beauty transposons as somatic mutagens to discover cancer genes in hematopoietic tumors and sarcomas has been documented. Here, we discuss the future of Sleeping...Full Text Available

2007-01-01

Mouth Opening During Sleep may be a Critical Predictor of Surgical Outcome after Uvulopalatopharyngoplasty for Obstructive Sleep Apnea

Study objective:To describe sleep characteristics and rapid eye movement (REM) sleep behavior disorder in patients with Guadeloupean atypical parkinsonism (Gd-PSP), a tauopathy resembling...Full Text Available

2007-08-01

Circadian Rhythm Sleep Disorders: Part I, Basic Principles, Shift Work and Jet Lag DisordersAn American Academy of Sleep Medicine Review

Study Objectives:To evaluate the value of mouth opening during sleep for predicting surgical outcomes after uvulopalatopharyngoplasty (UPPP).Methods:Retrospectively,...Full Text Available

2010-04-15

Objective:This the first of two articles reviewing the scientific literature on the evaluation and treatment of circadian rhythm sleep disorders (CRSDs), employing the methodology...Full Text Available

2007-11-01

Chapter 17 - NASAPeople

A VIEW FROM FEW - Kennedy Space Center - Home - NASA

CSRS retirees can use accrued sick leave to increase their annuities; however, sick leave cannot be used for retirement eligibility purposes. If you are a FERS ...

7 1 Will Technology, Incorporated X - Marshall Space Flight Center ...

credited for unused sick leave when they retire.) The FERS Sick Leave Credit would provide the exact same benefit to FERS ...

Experience of isolated sleep paralysis in clinical practice in Nigeria.

reemployment, retirement (CSRS and FERS) severance pay, benefits, ... Advance Sick Leave Program, Military Leave, leave for blood donation, Sick Leave for ...

Physical findings in the upper airways related to obstructive sleep apnea in men and women

The supernatural fears associated with the experience of isolated sleep paralysis in the culture of developing countries is sometimes associated with the evolution of somatic symptoms of psychological...Full Text Available

1992-06-01

British Library Electronic Table of Contents (United Kingdom)

Conclusions. There are gender differences when it comes to the risk factors for sleep apnea. Large tonsils, a high tongue and a wide uvula are risk factors for sleep apnea in men, while large tonsils and a retrognathic mandible are risk factors in women. Upper airway abnormalities including mandibular retrognathia are, however, unable to predict sleep apnea among snorers being investigated for suspected sleep apnea. Objectives. To identify gender-specific risk factors for obstructive sleep apnea and the diagnostic performance from physical upper airway examinations among snoring men and women investigated because of suspected sleep apnea. Patients and methods. The dimensions of the uvula, tonsils, velopharynx and tongue, and nasal septal deviation, mandibular position, neck circumference, ...

2007-01-01

Women of ... - NASA LaRC's Office of Equal Opportunity Programs

Relations between respiratory symptoms and sickness among workers in the animal feed industry.

Apr 28, 1997 ... Is it possible to work at home (like if you're sick)? ..... covered under the Federal Employee's Retierement System (FERS), which is described ... can't drive, and would be on sick leave otherwise), or they can ask to telecommute ...

Chapter 2, A Quick-look at your Pay - NASAPeople

OBJECTIVE--The survey aimed at studying the associations between prevalent respiratory symptoms in an occupational population and sickness absence due to respiratory disorders. METHODS--A cross sectional...Full Text Available

1994-07-01

The pattern of isolated sleep paralysis among Nigerian nursing students.

You receive an annuity if eligible -- requires 18 months service for FERS; and 60 ... You may use up to 104 hours of your accrued sick leave to care for sick family ...

Snoring as a Risk Factor for Sexual Dysfunction in Community Men

In a cross-sectional study of the pattern of isolated sleep paralysis among the entire population of nursing students at the Neuropsychiatric Hospital in Abeokuta, Nigeria (consisting of 58 males and...Full Text Available

1992-01-01

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Shielding of Sleeping Beauty DNA Transposon-delivered Transgene Cassettes by Heterologous Insulators in Early Embryonal Cells

IntroductionSevere obstructive sleep apnea has been associated with sexual dysfunction; however, it is unclear whether milder forms of sleep disturbances might also...Full Text Available

2008-04-01

Metabolic, Endocrine, and Immune Consequences of Sleep Deprivation

The Sleeping Beauty (SB) transposon system represents an important alternative to viral integrating vector systems but may, as its viral counterparts, be subject to transcriptional silencing. To investigate...Full Text Available

2009-01-01

Germline mutagenesis mediated by Sleeping Beauty transposon system in mice

Over the last three to four decades, it has been observed that the average total hours of sleep have decreased to less than seven hours per person per night. Concomitantly, global figures relating to...Full Text Available

Catecholamine and Cortisol Levels during Sleep in Women with Irritable Bowel Syndrome

Following the descovery of its transposition activity in mammalian culture systems, the Sleeping Beauty (SB) transposon has since been applied to achieve germline mutagenesis in mice....Full Text Available

2007-01-01

Statistical Indicators Report.

Evidence suggests that patients with irritable bowel syndrome (IBS) are hyper-responsive to environmental, physical, and visceral stimuli. IBS patients also frequently report poor sleep quality....Full Text Available

2009-11-01

October 2003 Status of Forces Survey of DoD Civilians ...

... Sick leave usage amounts to 72.4 hours per employee. ... Quits are resignations and individual tran;fers to other Federal Agencies. ...

2011-05-14

Using Floor Cooling as an Approach to improve the Thermal Environment in the Sleeping Area in an Open Pig House

... h. Sick leave ..... 162 ... appraisals and approval of leave. ... Retirement System, FERS are employees ...

2004-03-01

British Library Electronic Table of Contents (United Kingdom)

In order to provide pigs a comfortable sleeping area in hot weather, a floor cooling system was designed and applied to production buildings. Experiments were conducted to compare the floor temperatures and to observe the lying behaviour of pigs in the sleeping area of the buildings with and without floor cooling system. The results showed that, without the floor cooling system, the floor temperature was nearly the same as the air temperature in the open pig house. With the floor cooling system, the floor temperature of the sleeping area was controlled at 22-26degreeC, even though the air temperature was as high as 34degreeC, which improved the comfort of the pigs in the sleeping area. The pig lying behaviour was greatly affected by the floor temperature. More than 85% of the pigs were lyi...

2006-01-01

Welcome The National Aeronautics and Space Administration (NASA) is

Voluntary Leave Transfer Program - NASA - NASAPeople

Mar 8, 2006 ... Some examples of leave options are annual leave, sick leave, .... (FERS). This three-tier system combines social security, a basic annuity ...

Untitled - NASA Technical Report Server (NTRS)

If you are a FERS employee (the current retirement system), you lose your sick leave if you do not return to Federal service. If you separate from the Federal ...

Sick leave and other types of nonvested leave are expensed as taken. ... Employees Retirement System (FERS), a defined benefit and contribution plan. ...

Theoretical Perspectives of Terrorist Enemies as Networks

BackgroundLate-onset sepsis in the premature infant is frequently revealed by severe, unusual and recurrent bradycardias. In view of the high morbidity and mortality...Full Text Available

2009-03-01

The Senior Executive Service. Views of Former Federal ...

... second way in which social science dif- fers from the ... it would have been better to leave it intact ... to deploy, returning with worn vessels and sick crews ...

2005-10-01

Retirement Plng Wrkshp FERS

... P ) FERS 4 ... i 25. Opportunity for better fringe benefits 1 outside of the Federal Sector (eg, sick leave, _ annual leave, health or life insurance) .... ...

1989-10-01

Personnel and Payroll Management; A Guide for the ...

The workshop topics consist of FERS, FEGLI, FEHBP, Disability, Deposit/Redeposit ; TSP, Annual/Sick Leave, Annuity Calculation, Best Date to Retire, COLA's, ...

PART I THE SCHEDULE SECTION B, SUPPLIES OR SERVICES AND ... - NASA

... 2. Federal Employees Retirement System (FERS) ... . 17 ... a. Straight and differential pay b. Bcnefits: retirement, sick leave, health insurance ...

1990-06-19

Office of Civilian Personnel Management Survey of Navy ...

Sick Leave: Receives 13 days paid leave per year. ... Under the FERS, the Government contributes 11.4% of the employees' base ...

OPERATIONS AND FURLOUGHS UNDER A GOVERNMENT - NASA

... far superior in its annual and sick leave policies. ... fair treatment with regard to leave requests, discipline ... Fifty-six percent of FERS employees use TSP ...

1990-11-01

NASA/Marshall Space Flight Center Cooperative Education Program

Apr 7, 2011 ... You cannot be in any type of pay status (e.g., annual leave, sick leave, .... Retirement System (FERS) and the Civil Service Retirement System ...

NASA's Strategic Human Capital Implementation Plan - NASA Headquarters

Co-op students hired since December 3, 1983 will be covered under FERS. ... amount of sick leave that can be accumulated for use in succeeding years. 11. ...

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Military Base Closures and Affected Defense Department Civil ...

o If retaining CSRS/FERS, transferred employee will be credited with accumulated sick leave o Be reimbursed for travel, transportation, relocation costs ...

LPR 3451.1 Effective Date - Langley Management System - NASA

... System (CSRS) and the Federal Employees Retirement System (FERS). ... retirement, thrift savings plan, annual and sick leave, severance pay and ...

2006-03-07

Job Opportunities - Office Of Human Capital Management - NASA

Apr 18, 2011 ... TOA period, sick leave may be granted for the period of ..... civil service retirement under the CSRS and FERS retirement programs. ...

JPRS Report, Near East & South Asia, Israel

Jun 6, 2011 ... Sick leave is earned at a rate of 4 hours per pay period. ... The Federal Employees Retirement System (FERS) is a three-tiered pension plan ...

Impact on Benefits: Part-Time Schedule

... more so when that and he is leaving it with ... reminds me of the story about the sick man who ... fers based on industrial cooperation and the establish- ...

1991-09-11

Jan 31, 2006 ... Sick leave accrues at the rate of 1 hour for each 20 hour in a pay status. ... FERS: All periods of service are used in determining the FERS ...

FY06 PAR.indb - NASA

Chapter 2 A Quick Look At Your Benefits and Pay RELEASED - NASA

Nov 15, 2006 ... Sick leave and other types of non-vested leave ... For FERS employees, NASA makes contributions of 10.7 percent to the defined benefit plan, ...

Change Agents Advisory Committee - Goddard Diversity Council - NASA

18 months service for FERS; 60 months service for CSRS employees. the period covered by your accrued, donated, and advanced sick leave & accrued and ...

CONTRACT NASI-20100 - NASA LaRC

Employees in a pay status earn sick leave at the rate of 4 hours each pay period .... Employees covered by the Federal Employees' Retirement System (FERS) ...

Benefits Processing Service Delivery Guide - NASA

nclude sick leave, vacation, holiday leave, military leave, or any type. NAS1- 201OO ..... Employees Retirement System (FERS , and the CSRS Offset. Under the ...

Sleeping Beauty Transposition From Nonintegrating Lentivirus

Dec 20, 2007 ... Process 5b Federal Employee Retirement System (FERS) Deposits and ..... CSRS, CSRS Offset, or FERS ..... Advanced Sick Leave and ...

Sleep and environmental context: interactive effects for memory

Lentiviral vectors enter cells with high efficiency and deliver stable transduction through integration into host chromosomes, but their preference for integration within actively transcribing genes...Full Text Available

2009-07-01

British Library Electronic Table of Contents (United Kingdom)

Sleep after learning is often beneficial for memory. Reinstating an environmental context that was present at learning during subsequent retrieval also leads to superior declarative memory performance. This study examined how post-learning sleep, relative to wakefulness, impacts upon context-dependent memory effects. Thirty-two participants encoded word lists in each of two rooms (contexts), which were different in terms of size, odour and background music. Immediately after learning and following a night of sleep or a day of wakefulness, memory for all previously studied words was tested using a category-cued recall task in room one or two alone. Accordingly, a comparison could be made between words retrieved in an environmental context which was the same as, or different to, that of the ...

2011-01-01

Sleep Symptoms as a Partial Mediator Between Combat Stressors and Other Mental Health Symptoms in Iraq War Veterans

British Library Electronic Table of Contents (United Kingdom)

Sleep symptoms are a prominent feature of mental health disorders like PTSD and depression. However, it is unknown whether sleep symptoms mediate the relationship between combat stress and these disorders. We examined the mediating role of sleep symptoms on the relationship between combat stress and PTSD; and the relationship between combat stress and depression using data from 576 Army veterans of the Iraq War surveyed in 2004. Correlational analyses revealed that when insomnia was included in the model, the correlation between combat stressors and other depression symptoms decreased by 65%; and when nightmares were included in the model, the correlation between combat stressors and other PTSD symptoms decreased by 69%. We replicated these analyses using individual items assessing PTSD an...

2010-01-01

Cold: Physiology, Protection and Survival

Attachment Styles and Sleep Measures in a Community-Based Sample of Older Adults

... is reduced: 1) by lack of oxygen, 2) in hypercapnia associated with closed rooms or tents, 3) by use of sleeping drugs, antipyretics, insulin, and 4 ...

1974-08-01

APOD: July 10, 1998 - Interacting Galaxies

BackgroundMeasures of attachment style are often used to appraise social and emotional health. In developmental literature, the concept of attachment is used to explain...Full Text Available

2009-06-01

A preliminary study of sleep in adolescents with bipolar disorder, ADHD, and non-patient controls

believe the system is similar to the face-on spiral and companion known as M51, the Whirlpool Galaxy. Tomorrow's picture: Sleeping Beauty < Archive | Index | Search | Calendar |...

2011-10-07

British Library Electronic Table of Contents (United Kingdom)

Mullin BC, Harvey AG, Hinshaw SP. A preliminary study of sleep in adolescents with bipolar disorder, ADHD, and non-patient controls.-Bipolar Disord 2011: 13: 425-432. 2011 The Authors.-Journal compilation 2011 John Wiley & Sons A/S. Objectives:- To compare the sleep of adolescents with bipolar disorder (BD) to groups of adolescents with attention-deficit hyperactivity disorder-combined type (ADHD-C) and those without psychopathology. Methods:- A sample of 13 adolescents diagnosed with BD who were not in the midst of a mood episode, 14 adolescents with ADHD-C, and 21 healthy controls, all between the ages of 11 and 17 years served as participants. They were psychiatrically evaluated using a structured diagnostic interview and completed four nights of in-home sleep monitoring using actigraph...

2011-01-01

Induction of Antibody Responses to African Horse Sickness Virus (AHSV) in Ponies after Vaccination with Recombinant Modified Vaccinia Ankara (MVA)

Locomotive engineers and their spouses: coffee consumption, mood, and sleep reports.

BackgroundAfrican horse sickness virus (AHSV) causes a non-contagious, infectious disease in equids, with mortality rates that can exceed 90% in susceptible horse populations....Full Text Available

Effects of Sleep Apnea Severity on Glycemic Control in Patients with Type 2 Diabetes Prior to Continuous Positive Airway Presssure Treatment

Locomotive engineers (train drivers) on irregular work schedules reported a general coffee consumption rate higher than that reported by a comparison sample of permanent shift factory workers. The present study examines the impact of this consumption on workday and non-workday sleep behaviour and mood ratings. Twenty-seven engineers and their spouses each completed daily logs for 30 consecutive days. Daily logs were then sorted into workday and non-workday categories. Workday sleep length was significantly shorter than non-workday sleep length for both engineers and spouses. For the engineers only, coffee consumption on workdays was higher than on non-workdays. This increased coffee consumption was correlated with longer sleep latency, increased negative mood, and decreased positive mood on both work and non-workdays. This was not true for spouses. These results may be related to a days-off carry-over ...

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British Library Electronic Table of Contents (United Kingdom)

Abstract Background: Obstructive sleep apnea (OSA), a highly prevalent condition, is independently associated with increased risks of developing type 2 diabetes mellitus (T2D) and metabolic syndrome. It is unclear, however, if the severity of OSA has any impact on glycemic control among patients with T2D. We therefore aimed to determine the independent association between OSA severity and glycosylated hemoglobin (HbA1c) in patients with T2D. Methods: This was an observational cross-sectional study of 52 consecutive patients attending the diabetes obesity clinic between January 2008 to February 2010 with risk factors for sleep apnea and who underwent polysomnography study. Clinical, demographic, and lifestyle data were recorded using a questionnaire. Results: Prevalence of OSA in this clini...

2011-01-01

Recognition of historic influenza epidemics from parish burial records: a test of prediction from a new hypothesis of influenzal epidemiology.

Randomised controlled trial of disclosure of emotionally important events in somatisation in primary care

On the current conception of the epidemiology of epidemic influenza, as caused by a mechanism of direct spread of the virus from the sick, epidemics must have travelled much more slowly in former times...Full Text Available

1983-10-01

Posion Prevention in the Home

ObjectiveTo test whether a disclosure intervention improves subjective health and reduces medical consumption and sick leave in somatising patients in general practice.DesignNon-blind...Full Text Available

2001-07-14

NSSC Customer Service - Payroll - + NSSC - NASA

The Poison Control Centre at Toronto's Hospital for Sick Children received over 25,000 telephone inquiries in 1981. Those at greatest risk of accidental poisoning are children under age five. Education...Full Text Available

1983-06-01

NASA Procedural Requirements - + NODIS Library - NASA

The 2010 leave year ends with pay period 201101 (ending January 1, 2011). ... The agencies must also ensure that FERS employees receive the appropriate Agency Automatic (1%) ... Voluntary Leave Transfer Program/Advance Sick Leave ...

International Applied Military Psychology Symposium (23rd) ...

and sick leave, and list of awardees. DESTROY WHEN 1. YEAR OLD. [GRS 1-12b] ...... FOR CSRS/FERS. RELATED. RECORDS,. DESTROY UPON. RECEIPT OF. OFFICIAL OPM ...

Hypothesis for induction and propagation of chemical sensitivity based on biopsy studies.

... 3 3 0 Short weekend leave 4 2 2 ... 30 30 0 Stay at sick bay 31 32 -1 ... fers massive losses of effectiveness in training. At this point, the predictive ...

1987-12-30

How much donated leave can I receive? - NSSC Information Center - NASA

The reactive airways dysfunction syndrome (RADS), the reactive upper airways dysfunction syndrome (RUDS), the sick building syndrome (SBS), and the multiple chemical sensitivity syndrome (MCS) are overlapping...Full Text Available

1997-03-01

Gender differences in disability after sickness absence with musculoskeletal disorders: five-year prospective study of 37,942 women and 26,307 men

Oct 28, 2009 ... Note: FERS employees become eligible for disability retirement after 18 ... Can I use advanced sick leave while I am on the Voluntary Leave ...

CDC - Seasonal Influenza (Flu) - Q & A: 2007-08 Influenza (Flu...

BackgroundGender differences in the prevalence and occupational consequences of musculoskeletal disorders (MSDs) are consistently found in epidemiological studies. The study investigated...Full Text Available

CDC - Seasonal Influenza (Flu) - Q & A: 2006-07 Influenza (Flu...

home when you are sick helps everyone you care about Questions & Answers Flu Vaccine: Q&A Vaccine Dosage & Administration Vaccine Supply for 2011-12 Season Vaccine Supply and...

2011-10-15

CDC - Seasonal Influenza (Flu) - Q & A about the 2010-2011 Flu...

home when you are sick helps everyone you care about Questions & Answers Flu Vaccine: Q&A Vaccine Dosage & Administration Vaccine Supply for 2011-12 Season Vaccine Supply and...

2011-10-15

piggyBac is a flexible and highly active transposon as compared to Sleeping Beauty, Tol2, and Mos1 in mammalian cells

home when you are sick helps everyone you care about Questions & Answers Flu Vaccine: Q&A Vaccine Dosage & Administration Vaccine Supply for 2011-12 Season Vaccine Supply and...

2011-10-15

Transgenesis in Xenopus using the Sleeping Beauty transposon system

A nonviral vector for highly efficient site-specific integration would be desirable for many applications in transgenesis, including gene therapy. In this study we directly compared the genomic integration...Full Text Available

2006-10-10

Sleep and Fatigue Symptoms in Children and Adolescents With CKD: A Cross-sectional Analysis From the Chronic Kidney Disease in Children (CKiD) Study

Transposon-based integration systems have been widely used for genetic manipulation of invertebrate and plant model systems. In the past decade, these powerful tools have begun to be used in...Full Text Available

2009-07-01

REM Sleep Percentage in Children with Autism Compared to Children with Developmental Delay and Typical Development

BackgroundAlthough symptoms of sleepiness and fatigue are common among adults with Chronic Kidney Disease (CKD), little is known about the prevalence of these symptoms...Full Text Available

2010-02-01

Predictive Value of Kushida Index and Acoustic Pharyngometry for the Evaluation of Upper Airway in Subjects With or Without Obstructive Sleep Apnea

ObjectiveTo compare objective polysomnographic parameters between three cohorts: children with autism, with typical development, and with developmental delay without...Full Text Available

2010-11-01

Peak flow rate records in the diagnosis of occupational asthma due to colophony.

Acoustic pharyngometry is a relatively new noninvasive method that quantifies geometrically complexed pharyngeal dimensions. Our study aimed to investigate the predictability and usefulness of acoustic...Full Text Available

2004-10-01

Nocturnal sleep, daytime sleepiness, and quality of life in stable patients on hemodialysis

Peak expiratory flow rate (PEFR) has been measured hourly from waking to sleeping in 29 workers with respiratory symptoms exposed to the fumes of soft soldering fluxes containing colophony (pine resin)....Full Text Available

1979-06-01

Interaction effects of ethanol and pyrazole in laboratory rodents

BackgroundAlthough considerable progress has been made in the treatment of chronic kidney disease, compromised quality of life continues to be a significant problem for patients...Full Text Available

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Enzymatic control of anhydrobiosis-related accumulation of trehalose in the sleeping chironomid, Polypedilum vanderplanki

1. Interactions of pyrazole and ethanol were studied in three laboratory test procedures. They included sleeping time in mice, rotor rod balance in rats and lever pressing behaviour of rats. 2....Full Text Available

1971-09-01

Effects of hypocretin (orexin) neuronal loss on sleep and extracellular adenosine levels in the basal forebrain

Larvae of an anhydrobiotic insect, Polypedilum vanderplanki, accumulate very large amounts of trehalose as a compatible solute on desiccation, but the molecular mechanisms underlying...Full Text Available

2010-10-01

A conditional transposon-based insertional mutagenesis screen for hepatocellular carcinoma-associated genes in mice

Neurons containing the neuropeptide hypocretin (orexin) are localized only in the lateral hypothalamus from where they innervate multiple regions implicated in arousal, including the basal forebrain....Full Text Available

2008-09-01

Mechanisms involved in the antinociception of petroleum ether fraction from the EtOH extract of Chrysanthemum indicum in mice

Here we describe a Sleeping Beauty (SB) transposition system that utilizes a conditional SB transposase allele, which can be activated by Cre...Full Text Available

2009-03-01

British Library Electronic Table of Contents (United Kingdom)

The petroleum ether fraction (PEF) from the EtOH extract of flowers and buds of Chrysanthemum indicum was evaluated on antinociception in mice using chemical and thermal models of nociception. PEF administered orally at doses of 188 and 376mg/kg produced significant inhibitions on chemical nociception induced by intraperitoneal acetic acid, subplantar formalin or capsaicin injections and on thermal nociception in the tail-flick test and the hot plate test. In the pentobarbital sodium-induced sleep time test and the open-field test, PEF neither enhanced the pentobarbital sodium-induced sleep time nor impaired the motor performance, indicating that the observed antinociception was unrelated to sedation or motor abnormality. In a measurement of core body temperature, PEF did not affect temper...

2011-01-01

Infant well-being following neonatal cardiac surgery

British Library Electronic Table of Contents (United Kingdom)

Aims and objectives.- To investigate infant well-being as measured by feeding and sleeping and parental support following discharge from the NICU in infants following major cardiac surgery. Background.- Infant feeding and sleeping have been identified as two of the most important concerns reported by parents. These concerns have been reported anecdotally for infants who have undergone cardiac surgery in the neonatal period. Design.- A prospective study using questionnaires and phone interviews followed a cohort of parents of neonates who underwent surgery in the neonatal period for congenital heart disease. Methods.- The study was conducted using validated questionnaires and phone interviews with a semi-structured questionnaire. The questionnaires were administered prior to discharge from ...

2011-01-01

Biochemical basis of circadian rhythms and diseases: With emphasis on post-traumatic stress disorder

British Library Electronic Table of Contents (United Kingdom)

Circadian rhythms affect several processes in the body physiology. This commentary revisits the topic of `metabolic basis of diseases' with a view to shed light on how cellular energy requirements feed-forward to a sequential signaling of hormonal response, blood glucose metabolism, antioxidant activities, and pathophysiology. Attempt is made to explain how diseases that may not appear to be closely related, such as bone metabolism and vasculopathy, have an increase in oxidative damage as a common underlying biochemistry. Importantly, this article identifies oxidative damage as an outcome of sleep disturbance and hypothesize that sleep complaint is not merely one of many resulting symptoms of PTSD, but a core feature that arise from trauma and gives rise to the stress biochemistry, which i...

2011-01-01

Hygiene in air pipes. Tasks and requirements on clean air devices; Hygiene in Luftleitungen. Aufgaben und Anforderungen an RLT-Anlagen

The amount of sleep obtained by locomotive engineers: effects of break duration and time of break onset

Space HVAC systems are to provide hygienical room air. Air change is necessary because of pollutants released from materials or production processes but also because of the presence of humans or animals who consume oxygen. Poor room climate and/or poor air hygiene do not only reduce the felt comfort but may also result in a loss or profitability and higher sickness rates. (orig.)

2006-07-01

British Library Electronic Table of Contents (United Kingdom)

Methods: A total of 253 locomotive engineers (249 male, 4 female, mean age 39.7 years) participated. Data were collected at 14 rail depots, where participants drove electric or diesel locomotives;...Full Text Available

2003-12-01

Table of Contents

Abstract Overall Numbers Small, But Study Finds SSRI Exposure, Autism Link Additional Drug Safety, Efficacy Data Needed for Pediatric Bipolar Disorder SGA Safety and Efficacy in Children and Adolescents Aripiprazole Safety and Tolerability for Irritability in Autism No Lisdexamfetamine Effect on Sleep Disturbances in Children With ADHD Sickle Cell Disease With Comorbid Depression Homeopathy in Psychiatry Manic Symptoms Induced by Marijuana in a Healthy Adolescent New Warnings Safety Labeling Changes

2011-01-01

Space HVAC engineering 2003. Part 1. An overview; Die Luft- und Klimatechnik 2003. Teil 1. Eine Bestandsaufnahme

No short-term effects of digital mobile radio telephone on the awake human electroencephalogram

The development of the space HVAC sector during the past 25 years is reviewed. It is shown how the importance of room climate has increased, as illustrated, e.g., by the concepts of 'thermal comfort', 'comfort', and 'sick building syndrome'. A sequel will be published in the next issue of KK. (orig.) [German] Der folgende Beitrag ist eine Bestandsaufnahme im Hinblick auf technologische Entwicklungen in der Klima- und Lueftungstechnik der letzten 25 Jahre, ein Zeitraum in dem sich einiges veraendert hat. Gleichzeitig wird deutlich, welcher Wandel sich bei der Bedeutung des Raumklimas in Gebaeuden vollzogen hat, indem beispielsweise Begriffe wie ''Behaglichkeit'', ''Komfort'' aber auch ''Sick Building Syndrom'' eine immer groessere Rolle spiel(t)en. Die Fortsetzung in der naechsten ...

2003-03-01

Functional MRI of the pharynx in obstructive sleep apnea (OSA) with rapid 2-D flash sequences

A recent study reported the results of an exploratory study of alterations of the quantitative sleep profile due to the effects of a digital mobile radio telephone. Rapid eye movement (REM) was suppressed, and the spectral power density in the 8--13 Hz frequency range during REM sleep was altered. The aim of the present study was to illuminate the influence of digital mobile radio telephone on the awake electroencephalogram (EEG) of healthy subjects. For this purpose, the authors investigated 34 male subjects in a single-blind cross-over design experiment by measuring spontaneous EEGs under closed-eyes condition from scalp positions C{sub 3} and C{sub 4} and comparing the effects of an active and an inactive digital mobile radio telephone (GSM) system. During exposure of nearly 3.5 min to the 900 MHz electromagnetic field pulsed at a frequency of 217 Hz and with a pulse width of 580 {micro}s, the authors could not detect any difference in the ...

1997-05-01

Analgesic activity of the aqueous fraction from the ethanolic extract of Chrysanthemum indicum in mice.

Functional imaging of the pharynx used to be the domain of cineradiography, CT and ultrafast CT. The development of modern MRI techniques led to new access to functional disorders of the pharynx. The aim of this study was to implement a new MRI technique to examine oropharyngeal obstructive mechanisms in patients with obstructive sleep apnea (OSA). Sixteen patients suffering from OSA and 6 healthy volunteers were examined on a 1.5 T whole-body imager ('Vision', Siemens, Erlangen Medical Engineering, Germany) using a circular polarized head coil. Imaging was performed with 2D flash sequences in midsagittal and axial planes. Patients and volunteers were asked to breathe normally through the nose and to simulate snoring and the Mueller maneuver during magnetic resonance imaging (MRI). Prior to MRI, all patients underwent an ear, nose and throat (ENT) examination, functional fiberoptic nasopharyngoscopy and polysomnography. A temporal resolution of 6 images/s and an ...

The aqueous fraction (AF) of an ethanolic extract from Chrysanthemum indicum was evaluated for analgesic activity in mice using chemical and thermal models of nociception. Given orally, AF at doses of 300 and 600 mg/kg produced significant inhibitions on chemical nociception induced by intraperitoneal acetic acid, subplantar formalin/capsaicin injections and on thermal nociception in the tail-flick test and in the hot plate test. In the pentobarbital sodium-induced sleeping time test and the open-field test, AF neither significantly enhanced the pentobarbital sodium-induced sleeping time nor impaired the motor performance, indicating that the observed analgesic activity was unlikely due to sedation or motor abnormality. In a measurement of core body temperature, AF did not affect temperature within 80 min. Moreover, the effective dose (600 mg/kg) also showed no toxicity within 7 days. These results suggested further that AF produced analgesic ...

2011-07-01

Radiobiology

Adrenocortical (dys)function in septic shock - A sick euadrenal state

This text-book (electronic book - multi-media CD-ROM) constitutes a course-book - author's collection of lectures. It consists of 13 lectures in which the reader acquaints with the basis of radiobiology: Introduction to radiobiology; Physical fundamentals of radiobiology; Radiation of cells; Modification of radiation damage of cells; Reparation of radiation damage of cells; Radiation syndromes and their modification; Radiation injury; Radiation damage of tissues; Effect of radiation on embryo and fetus; Biological effects of incorporated radionuclides; Therapy of acute irradiation sickness; Delayed consequences of irradiation; Radiation oncology and radiotherapy. This course-book may be interesting for students, post-graduate students of chemistry, biology, physics, medicine as well as for teachers, scientific workers and physicians. (author)

British Library Electronic Table of Contents (United Kingdom)

A central feature of the endocrine pathophysiology of septic shock is thought to be the existence of adrenal dysfunction. Based on changes in glucocorticoid secretion and responsiveness, protein binding, and activity. These changes have been described by the terms "Relative Adrenal Insufficiency" (RAI), or "Critical Illness Related Corticosteroid Insufficiency" (CIRCI), and form part of the rationale for trials of glucocorticoid treatment in septic shock. Diagnostic criteria for these conditions have been based on plasma cortisol profiles and have proven notoriously difficult to establish. The uncertainty in this area arises from the inability of current tests to clearly identify who is truly glucocorticoid "deficient" at a cellular level, and hence who requires supplemental glucocorticoid...

2011-01-01

Action of radiation on biosynthesis of hemoglobin and some of its electrophoretic fractions

Activity patterns in a panel of outdoor workers exposed to oxidant pollution

Biosynthesis of hemoglobin and some of its electrophoretic fractions in red cells of peripheral blood and spleen of irradiated (650 R) rats has been studied. Hemoglobin synthesis is found to be most drastically inhibited in the first and second fractions on the first and eighth days after irradiation and in the fifth and sixth fractions on the eighth day (less expressed). The synthesis is restored on the twelfth day, the process under study proceeding more slowly in the above-mentioned fractions than in others. In the course of radiation sickness, the biosynthesis of certain hemoglobin fractions varies differently in the hemoglobin-synthesizing cells of peripheral blood than in the cells of spleenic erythroid series.

The value of cardiac catheterization and cineangiography in infantile lobar emphysema

We investigated summer activity patterns in a panel of volunteers drawn from a population segment with potentially high exposure to ambient oxidant pollution. The subjects were 15 men and 5 women aged 19-50, all of whom worked outdoors in the Los Angeles area at least 10 hr per week. The general approach was to (i) calibrate the relationship between ventilation rate (VR) and heart rate (HR) for each subject in controlled exercise; (ii) have subjects monitor their own normal activities with diaries and electronic HR recorders; (iii) estimate VR from HR recordings; and (iv) relate VR with diary descriptions of activities. Calibration data were fit to the equation log (VR) = (intercept) + (slope x HR), intercept and slope being determined separately for each individual to provide a specific equation to predict her/his VR from measured HR. Individuals' correlation coefficients relating log (VR) with HR ranged from 0.83 to 0.95. Subjects monitored themselves for three 24-hr periods ...

1991-10-01

Sound climate installations. Gezonde klimaatinstallaties

Lobar emphysema is an uncommon cause of respiratory distress in infancy. Congenital heart disease is seen in about 20% of the patients with infantile (congenital) lobar emphysema. We described six infants with lobar emphysema. In three of them a congenital heart disease was demonstrated by cardiac catheterization and cineangiography; two had a tetralogy of Fallot with right aortic arch and the third infant a ventricular septal defect. The pulmonary angiography showed stretching of the arteries with very poor filling of the peripheral arteries and a characteristic smaller pulmonary vein in the affected lobe. In all the six patients the pulmonary artery pressure was normal. All the patients underwent lobectomy with good results. We feel that a preoperative cardiac catheterization and cineangiography is of value in this very sick group of infants. (orig.).

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Multi-scale evaluation of river health in Liao River Basin, China

An uncomfortable thermal climate, draft complaints and a bad airquality are often related to the climate installation. To avoid badfunctioning of the system a number of preconditions has to be fulfilledwith regard to design, planning and execution, adjustments, completion,control, maintenance and management of the installations. First threetypes of health problems in buildings are shortly discussed: buildingrelated illness, sick building syndrome and building or installationrelated complaints. Then some functions of the climate installationsare described: air filtration, filter classes and filter quality, aswell as investment costs for better filters. Next the causes for thecomplaints are dealt with: air conditioning, ventilation, air quality,and temperatures. Subsequently health affecting aspects in relation tothe climate systems are discussed: outdoor air pollution,microorganisms, bacteria (legionella pneumophila), allergies, ionneutralization and performance of ...

1989-10-01

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British Library Electronic Table of Contents (United Kingdom)

Previous studies on river health evaluation mainly focused on characterizations at a river-corridor scale and ignored the complex interactions between the river ecosystem and other components of the river basin. Based on the consideration of the interactions among rivers, associated river basin and habitats, an assessment framework with multi-scale indicators was developed. An index system divided among these three scales to characterize the health of river ecosystems in China???s Liao River Basin was established. Set pair analysis was applied to integrate the multi-scale indicators and determine the health classes. The evaluation results indicated that the rivers in the western and eastern zones of the Liao River were classified as sick, and rivers in the main stream of the Liao and Hunta...

2011-01-01

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Incidence of zoonotic diseases in military workingn> dogs serving in Operations Desert Shield and Desert Storm.

Traumatic and Non-traumatic Fibromyalgia Syndrome: Impact Assessment on the Life Quality of Women

The United States deployed 118 military working dogs (MWDs) to the Persian Gulf theater during Operations Desert Shield and Desert Storm. This study is a retrospective descriptive study of medical records of these deployed dogs, with the objective to determine whether there were infectious or parasitic diseases with a zoonotic potential in a sentinel population of MWDs that may be of concern to Persian Gulf veterans. Fifty-one percent of visits to veterinary treatment facilities during deployment were for illness or injury. Potential zoonotic conditions accounted for 21% of the total visits, 41% of the "sick-call" visits, and 63% of presentations for illness to veterinary treatment facilities. This study did not determine whether the diseases treated were transmitted between MWDs and the troops. Although the etiologic agents were not determined in these cases, no evidence was found supporting new or reemerging illnesses in this population of dogs. PMID:11272705

2001-02-01

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British Library Electronic Table of Contents (United Kingdom)

Objective To investigate the impact on life quality of women with traumatic and non-traumatic origin fibromyalgia syndrome [FMS]. Method Women affected with FMS were selected and divided into two groups: those with traumatic origin FMS [Group 1] and those with non-traumatic origin FMS [Group 2]. A standard question form was used for the research, as well as the fibromyalgia impact questionnaire [FIQ] for evaluation of life quality. Results Seventy-two patients, 34 for Group 1 and 38 for Group 2 were analyzed. The main triggering symptoms were divorce [23.5 percent of cases] and death in the family [23.5 percent of cases]. In addition to diffuse pain, the main symptoms presented were poor sleep quality, weariness, and paresthesia, with no difference between the groups; migraine had a greate...

2011-01-01

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Subthreshold depression in Parkinson's disease

British Library Electronic Table of Contents (United Kingdom)

AbstractBackground: Quality of life in Parkinson patients with subthreshold depression could be improved if the prevalence and symptom profile were better understood. Methods: Our study used standard DSM-IV and Judd criteria as well as motor, depression, and quality-of-life scales to investigate a sample of 110 nondemented Parkinson patients. This led to formation of nondepressed (48.2%), subthreshold depressed (25.5%), and depressed (26.4%) groups. Results: Quality of life was seen to be significantly lower in subthreshold depressed patients than in the nondepressed, and there were differences in the frequency of depressive symptoms that partially overlapped with nonmotor symptoms of vegetative origin in Parkinson's disease (appetite, sleep disorders). Key measures of depression (diminish...

2011-01-01

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Spatial ability and STEM: A sleeping giant for talent identification and development

British Library Electronic Table of Contents (United Kingdom)

Spatial ability is a powerful systematic source of individual differences that has been neglected in complex learning and work settings; it has also been neglected in modeling the development of expertise and creative accomplishments. Nevertheless, over 50years of longitudinal research documents the important role that spatial ability plays in educational and occupational settings wherein sophisticated reasoning with figures, patterns, and shapes is essential. Given the contemporary push for developing STEM (science, technology, engineering, and mathematics) talent in the information age, an opportunity is available to highlight the psychological significance of spatial ability. Doing so is likely to inform research on aptitude-by-treatment interactions and Underwood's (1975) idea to utili...

2010-01-01

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Severe mood dysregulation: In the "light" of circadian functioning

British Library Electronic Table of Contents (United Kingdom)

Severe affective and behavioral dysregulation, labeled as severe mood dysregulation (SMD), is a widely spread phenomenon among adolescent psychiatric patients. This phenotype constitutes severe impairment across multiple settings, including various symptoms, such as non-episodic anger, mood instability, and hyperarousal. Moreover, SMD patients often show depression and reduced need for sleep. Despite a lifetime prevalence of 3.3%, systematic research is still scarce, and treatments that have been established do not account for the range of symptoms present in SMD. Considering the circadian dysfunctions, two hormones, melatonin and cortisol, are essential. When these hormones are dysregulated, the circadian rhythm gets out of synchrony. Since evidence is emerging showing that the worse the ...

2011-01-01

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Interactions of -lactoglobulin with serotonin and arachidonyl serotonin

British Library Electronic Table of Contents (United Kingdom)

Abstract -Lactoglobulin (-LG) is a lipocalin, which is the major whey protein of cow's milk and the milk of other mammals. However, it is absent from human milk. The biological function of -LG is not clear, but its potential role in carrying fatty acids through the digestive tract has been suggested. -LG has been found in complexes with lipids such as butyric and oleic acids and has a high affinity for a wide variety of compounds. Serotonin (5-hydroxytryptamine, 5-HT), an important compound found in animals and plants, has various functions, including the regulation of mood, appetite, sleep, muscle contraction, and some cognitive functions such as memory and learning. In this study, the interaction of serotonin and one of its derivatives, arachidonyl serotonin (AA-5HT), with -LG was invest...

2011-01-01

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Effects of continuous exposure to carbon monoxide on auditory vigilance in man

Toxicity of ultraviolet-irradiated halothane in mice

Six different groups of non-smoking young male subjects were studied separately for 18 consecutive days each in a closed controlled-environmental human exposure chamber. Each group was subjected to a 5-day control period in fresh air followed successively by an 8-day period of continuous exposure to 50 ppm, 15 ppm or 0 ppm (control) by volume of carbon monoxide (CO) in air, and a 5-day recovery period in fresh air. The subjects performed a 1-h auditory vigilance task every day at the same time of day in a fixed qualitative, quantitative, and temporal relationship with food intake, consumption of stimulating beverages, physical activity, and sleep. It was concluded that such CO exposure, involving the continuous carriage of carboxyhaemoglobin loads up to 7%, was without significant effect on auditory vigilance.

1981-01-01

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Results of a cross-sectional study on the association of electromagnetic fields emitted from mobile phone base stations and health complaints; Ergebnisse einer Querschnittsstudie zum Zusammenhang von elektromagnetischen Feldern von Mobilfunksendeanlagen und unspezifischen gesundheitlichen Beschwerden

One such agent is the widely used anesthetic, halothane. To study the toxicity of u.v. decomposed halothane, mice were exposed to anesthetic concentrations (1.3%) of non- and u.v.-irradiated halothane in oxygen for 90 min. Halothane sleeping times increased from 14.3 min to 72.5 min. Microsomal mixed function oxidase activity decreased, as shown by prolonged pentobarbital sleeping times 1 day after exposure to halothane and irradiated halothane (54.6 min and 149.1 min, respectively, as compared to a 34.6-min control). Quantitative and qualitative differences were found in the amount of (/sup 14/C)-pentobarbital metabolites excreted by u.v. irradiated halothane-exposed mice compared to either oxygen or non-irradiated halothane-exposed groups. In addition, serum glutamic-oxalacetic transaminase (SGOT) of irradiated halothane-exposed mice increased to 233% of the control values, and serum glutamic-pyruvic transaminase (SGPT) were 377% of control ...

1982-01-01

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Neurotoxicological effects of cinnabar (a Chinese mineral medicine, HgS) in mice

Background: Despite the fact that adverse health effects are not confirmed for exposure to radiofrequency electromagnetic field (RFEMF) levels below the limit values, as defined in the guidelines of the International Commission on Non-Ionizing Radiation Protection, many persons are worried about possible adverse health effects caused by the RF-EMF emitted from mobile phone base stations, or they attribute their unspecific health complaints like headache or sleep disturbances to these fields. Method: In the framework of a cross-sectional study a questionnaire was sent to 4150 persons living in predominantly urban areas. Participants were asked whether base stations affected their health. Health complaints were measured with standardized health questionnaires for sleep disturbances, headache, health complaints and mental and physical health. 3,526 persons responded (85%) to the questionnaire and 1,808 (51%) agreed to dosimetric measurements in ...

2010-07-01

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Can a model-independent analysis be made for the matter distribution of "4"0Ca from 166 MeV #alpha# particle scattering

Cinnabar, a naturally occurring mercuric sulfide (HgS), has long been used in combination with traditional Chinese medicine as a sedative for more than 2000 years. Up to date, its pharmacological and toxicological effects are still unclear, especially in clinical low-dose and long-term use. In this study, we attempted to elucidate the effects of cinnabar on the time course of changes in locomotor activities, pentobarbital-induced sleeping time, motor equilibrium performance and neurobiochemical activities in mice during 3- to 11-week administration at a clinical dose of 10 mg/kg/day. The results showed that cinnabar was significantly absorbed by gastrointestinal (G-I) tract and transported to brain tissues. The spontaneous locomotor activities of male mice but not female mice were preferentially suppressed. Moreover, frequencies of jump and stereotype-1 episodes were progressively decreased after 3-week oral administration in male and female mice. ...

2007-10-15

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Activity patterns in elementary and high school students exposed to oxidant pollution

It is proposed to extract, independently of any nuclear model, the "4"0Ca matter density from an analysis of the elastic scattering of "1"6"6 MeV alpha particles. The scattering is described using an optical potential whose real part is evaluated by folding the matter density with a nucleon-alpha interaction. Following the procedure proposed by Sick (Nucl. Phys. A; 218: 509 (1974)) and Phys. Lett.; 44B; 62 (1975)) for the analysis of electron scattering data, the density is represented by a sum of gaussians whose amplitudes are deduced in fitting, via a chi"2 minimization, the experimental cross section data. This method determines the envelope of densities for different parameters of gaussians: width, spacing. The envelope of the moments of these densities are presented and the root-mean-square radius is extracted. It is concluded that only the nuclear surface is well studied by the alpha particle scattering. (author).

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Functional MRI of the pharynx in obstructive sleep apnea (OSA) with rapid 2-D flash sequences; Funktionelle MRT des Pharynx bei obstruktiver Schlafapnoe (OSA) mit schnellen 2D-FLASH-Sequenzen

We investigated activity patterns of 17 elementary school students aged 10-12, and 19 high school students aged 13-17, in suburban Los Angeles during the oxidant pollution season. Individuals' relationships between ventilation rate (VR) and heart rate (HR) were calibrated' in supervised outdoor walking/jogging. Log VR was consistently proportional to HR; although calibrations' were limited by a restricted range of exercise, and possibly by artifact due to mouthpiece breathing, which may cause overestimation of VR at rest. Each subject then recorded activities in diaries, and recorded HR once per minute by wearing Heart Watches, over 3 days (Saturday-Monday). For each activity the subject estimated a breathing rate--slow (slow walking), medium (fast walking), or fast (running). VR ranges for each breathing rate and activity type were estimated from HR recordings. High-school students' diaries showed their aggregate distribution of waking hours as 68% ...

1992-07-01

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Indoor air. Seminar of Zentrale Informationsstelle, Umweltberatung Bayern. Vol. 2; Innenraumluft. Seminar der Zentralen Informationsstelle, Umweltberatung Bayern. Bd. 2

Functional imaging of the pharynx used to be the domain of cineradiography, CT and ultrafast CT. The development of modern MRI techniques led to new access to functional disorders of the pharynx. The aim of this study was to implement a new MRI technique to examine oropharyngeal obstructive mechanisms in patients with obstructive sleep apnea (OSA). Sixteen patients suffering from OSA and 6 healthy volunteers were examined on a 1.5 T whole-body imager (`Vision`, Siemens, Erlangen Medical Engineering, Germany) using a circular polarized head coil. Imaging was performed with 2D flash sequences in midsagittal and axial planes. Patients and volunteers were asked to breathe normally through the nose and to simulate snoring and the Mueller maneuver during magnetic resonance imaging (MRI). Prior to MRI, all patients underwent an ear, nose and throat (ENT) examination, functional fiberoptic nasopharyngoscopy and polysomnography. A temporal resolution of 6 images/s and an ...

1996-03-01

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Case report: Denys- Drash syndrome.

This seminar dealt with the subject of indoor air pollution and welcomed participants from environmental consultancy agencies and authorities and institutions related with environmental protection. Leading scientists from research and authorities presented the current state of knowledge abut the risks of indoorair pollution. The papers contained in these proceedings addressed: room climate and sick-building syndrome; allergens in indoor spaces; pollutants emitted by exemplary building materials; pollutant levels of organic compounds in indoor spaces; air quality in motor vehicle interiors; indoor air pollution - risk assessment and need for actions. (Uhe) [Deutsch] Das Seminar zum Thema Innenraumluft wurde fuer TeilnehmerInnen von Umweltberatungsstellen und anderen mit Umwelt betrauten Behoerden und Institutionen veranstaltet. Fuehrende Wissenschaftlerinnen aus Forschung und Behoerden stellten den aktuellen Stand des Wissens ueber Risiken der Innenraumbelastung aus ...

1994-02-01

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Systemic responses to inhaled ozone in mice: cachexia and down-regulation of liver xenobiotic metabolizing genes

BACKGROUND: Denys-Drash Syndrome (DDS) is an uncommon disorder that appears sporadically and in rare cases may be inherited as an autosomal dominant trait It manifests either at birth or within the first year of life and typically consists of the triad of congenital nephropathy, Wilms tumour and intersex disorder. CASE REPORT: A 10 year-old Caucasian girl was referred to the Dental Department, at Glasgow Royal Hospital for Sick Children by her Paediatric Nephrologist Consultant. The patient was being teased by her peers over her markedly discoloured teeth. The dental history revealed that the patient was a regular dental attendee from an early age. She was dentally anxious having only experienced dental treatment under general anaesthesia (GA) when she was 4 years old. Apparently her primary dentition also showed a generalised discolouration. TREATMENT: This consisted of multiple visits for diet analysis and tooth brushing instruction with the use of disclosing ...

2007-12-01

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Optimal capacity of the battery energy storage system in a power system

Rats or mice acutely exposed to high concentrations of ozone show an immediate and significant weight loss, even when allowed free access to food and water. The mechanisms underlying this systemic response to ozone have not been previously elucidated. We have applied the technique of global gene expression analysis to the livers of C57BL mice acutely exposed to ozone. Mice lost up to 14% of their original body weight, with a 42% decrease in total food consumption. We previously had found significant up-regulation of genes encoding proliferative enzymes, proteins related to acute phase reactions and cytoskeletal functions, and other biomarkers of a cachexia-like inflammatory state in lungs of mice exposed to ozone. These results are consistent with a general up-regulation of different gene families responsive to NF-#kappa#B in the lungs of the exposed mice. In the present study, we observed significant down-regulation of different families of mRNAs in the livers of the exposed mice, ...

2005-10-15

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