WorldWideScience
1

Cutaneous gallium uptake in patients with AIDS with mycobacterium avium-intracellulare septicemia  

International Nuclear Information System (INIS)

Gallium imaging is increasingly being used for the early detection of complications in patients with AIDS. A 26-year-old homosexual man who was HIV antibody positive underwent gallium imaging for investigation of possible Pneumocystis carinii pneumonia. Widespread cutaneous focal uptake was seen, which was subsequently shown to be due to mycobacterium avium-intracellulare (MAI) septicemia. This case demonstrates the importance of whole body imaging rather than imaging target areas only, the utility of gallium imaging in aiding the early detection of clinically unsuspected disease, and shows a new pattern of gallium uptake in disseminated MAI infection.

2

What's new in target volume definition for radiologists in ICRU Report 71? How can the ICRU volume definitions be integrated in clinical practice?  

UK PubMed Central (United Kingdom)

AbstractThe optimal definition of the size, shape and location of gross tumour volume is one of the most important steps in the planning of radiation therapy, and necessitates a proper...Full Text Available

3

Production of a helium beam in a focused ion beam machine using an electron beam ion trap  

International Nuclear Information System (INIS)

Gallium liquid-metal ion sources that have been introduced in the late 1970s have allowed the development of a new class of micro- and nanofabrication tools collectively denominated as focused ion beam (FIB) machines. To investigate the potential of a helium beam in such a FIB instrument the authors have tested a room-temperature electron beam ion trap coupled with a high resolution FIB machine. In this letter they present their first results in target imaging using a helium beam with a resolution that allows to account for a beam diameter in the submicrometer range.

2007-02-19

4

A Targeted Bypass Screen Identifies Ynl187p, Prp42p, Snu71p, and Cbp80p for Stable U1 snRNP/Pre-mRNA Interaction?  

UK PubMed Central (United Kingdom)

To understand how DEXD/H-box proteins recognize and interact with their cellular substrates, we have been studying Prp28p, a DEXD/H-box splicing factor required for switching the U1 snRNP with the U6...Full Text Available

2009-07-01

5

Vacancy ordering and oxygen dynamics in oxide ion conducting La1-xSrxGa1-xMgxO3-x ceramics: 71Ga, 25Mg and 17O NMR  

International Nuclear Information System (INIS)

The oxygen vacancies distribution in the rigid lattice and the thermally activated motion of oxygen atoms are studied in La1-xSrxGa1-xMgxO3-x (x=0.00; 0.05; 0.10; 0.15 and 0.20) compounds. For that 71Ga, 25Mg and 17O NMR was performed from 100 K up to 670 K, and ion conductivity measurements were carried out up to 1273 K. The comparison of the electric field gradients at the Ga- and Mg-sites evidences that oxygen vacancies appear exclusively near gallium cations as a species trapped below room temperature in local clusters, GaO5/2-#square#-GaO5/2. These clusters decay at higher temperature into mobile constituents of the structural octahedra Ga(O5/6#square#1/6)6/2. At the same time, the nearest octahedral oxygen environment of magnesium cations persists at different doping levels. The case of two adjacent vacant anion sites is found highly unlikely within the studied doping range. The thermally activated oxygen motion starts to develop above ...

2011-01-01

6

NREL preprints for the 23rd IEEE Photovoltaic Specialists Conference  

Energy Technology Data Exchange (ETDEWEB)

Topics covered include various aspects of solar cell fabrication and performance. Aluminium-gallium arsenides, cadmium telluride, amorphous silicon, and copper-indium-gallium selenides are all characterized in their applicability in solar cells.

1993-05-01

7

Measurement of achievable plutonium decontamination from gallium by means of Purex solvent extraction  

Energy Technology Data Exchange (ETDEWEB)

Gallium is present in surplus weapons-grade plutonium (WG-Pu) at a concentration of approximately 1 wt %. Plans are to dispose of surplus WG-Pu by converting it to UO{sub 2}-PuO{sub 2} mixed oxide (MOX) fuel and irradiating it in commercial power reactors. However, the presence of high concentrations of gallium in plutonium poses a potential corrosion problem during the process of MOX fuel irradiation. The batch experiments performed in this study were designed to measure the capability of the PUREX solvent extraction process to separate gallium from plutonium under idealized conditions. Radioactive tracing of the gallium with {sup 72}Ga enabled the accurate measurement of low concentrations of extractable gallium. The experiments approximated the proposed flowsheet for WG-Pu purification, except that only one stage was used for each process: extraction, scrubbing, and stripping. ...

2000-07-01

8

Mineralogy and geochemistry of the No. 6 Coal (Pennsylvanian) in the Junger Coalfield, Ordos Basin, China  

Energy Technology Data Exchange (ETDEWEB)

This paper discusses the mineralogy and geochemistry of the No. 6 Coal (Pennsylvanian) in the Junger Coalfield, Ordos Basin, China. The results show that the vitrinite reflectance (0.58%) is lowest and the proportions of inertinite and liptinite (37.4% and 7.1%, respectively) in the No. 6 Coal of the Junger Coalfield are highest among all of the Late Paleozoic coals in the Ordos Basin. The No. 6 Coal may be divided vertically into four sections based on their mineral compositions and elemental concentrations. A high boehmite content (mean 6.1%) was identified in the No. 6 Coal. The minerals associated with the boehmite in the coal include goyazite, rutile, zircon, and Pb-bearing minerals (galena, clausthalite, and selenio-galena). The boehmite is derived from weathered and oxidized bauxite in the weathered crust of the underlying Benxi Formation (Pennsylvanian). A high Pb-bearing mineral content of samples ZG6-2 and ZG6-3 is likely of hydrothermal origin. The No. 6 ...

2006-04-03

10

New neutron-rich isotopes in the scandium-to-nickel region, produced by fragmentation of a 500 MeV/u {sup 86}Kr beam  

Energy Technology Data Exchange (ETDEWEB)

We have measured production cross-sections of the new neutron-rich isotopes {sup 58}Ti, {sup 61}V, {sup 63}Cr, {sup 66}Mn, {sup 69}Fe, {sup 71}Co and neighbouring isotopes that have been identified as projectile fragments from reactions between a 500 MeV/u {sup 86}Kr beam and a beryllium target. The isotope identification was performed with the zero-degree magnetic spectrometer FRS at GSI, using in addition time-of-flight and energy-loss mesurements. The experimental production cross-sections for the new nuclides and neighbouring isotopes are compared with an empirical parameterization. The resulting prospects for reaching even more neutron-rich isotopes, such as the doubly-magic nuclide {sup 78}Ni, are discussed. (orig.).

1991-10-01

11

New neutron-rich isotopes in the scandium-to-nickel region, produced by fragmentation of a 500 MeV/u sup 86 Kr beam  

Energy Technology Data Exchange (ETDEWEB)

We have measured production cross-sections of the new neutron-rich isotopes {sup 58}Ti, {sup 61}V, {sup 63}Cr, {sup 66}Mn, {sup 69}Fe, {sup 71}Co and neighbouring isotopes that have been identified as projectile fragments from reactions between a 500 MeV/u {sup 86}Kr beam and a beryllium target. The isotope identification was performed with the zero-degree magnetic spectrometer FRS at GSI, using in addition time-of-flight and energy-loss measurements. The experimental production cross-sections for the new nuclides and neighbouring isotopes are compared with an empirical parametrization. The resulting prospects for reaching even more neutronrich isotopes, such as the doubly-magic nuclide {sup 78}Ni, are discussed. (orig.).

1992-07-01

12

New neutron-rich isotopes in the scandium-to-nickel region, produced by fragmentation of a 500 MeV/u "8"6Kr beam  

International Nuclear Information System (INIS)

We have measured production cross-sections of the new neutron-rich isotopes "5"8Ti, "6"1V, "6"3Cr, "6"6Mn, "6"9Fe, "7"1Co and neighbouring isotopes that have been identified as projectile fragments from reactions between a 500 MeV/u "8"6Kr beam and a beryllium target. The isotope identification was performed with the zero-degree magnetic spectrometer FRS at GSI, using in addition time-of-flight and energy-loss measurements. The experimental production cross-sections for the new nuclides and neighbouring isotopes are compared with an empirical parametrization. The resulting prospects for reaching even more neutronrich isotopes, such as the doubly-magic nuclide "7"8Ni, are discussed. (orig.).

13

Liquid Nitrogen Dewar Loading at KSC for STS-71 Flight  

Science.gov (United States)

Liquid nitrogen dewar loading at Kennedy Space Center for STS-71 flight with Stan Koszelak (right),

1995-01-01

14

Patterns of gallium-67 scintigraphy in patients with acquired immunodeficiency syndrome and the AIDS related complex  

Energy Technology Data Exchange (ETDEWEB)

Thirty-two patients with AIDS related complex (ARC) or acquired immunodeficiency syndrome (AIDS) underwent /sup 67/Ga scans as part of their evaluation. Three patterns of /sup 67/Ga biodistribution were found: lymph node uptake alone; diffuse pulmonary uptake; normal scan. Gallium-67 scans were useful in identifying clinically occult Pneumocystis carinii pneumonia in seven of 15 patients with ARC who were asymptomatic and had normal chest radiographs. Gallium scans are a useful ancillary procedure in the evaluation of patients with ARC or AIDS.

1987-07-01

15

Gallium Arsenide Pilot Line for High Performance ...  

Science.gov (United States)

... used in our aluminum process include a barrier to isolate aluminum from the gold-based ohmic contacts, thereby preventing "purple plague," and a ...

1991-08-08

16

Effect of Gallium Focused Ion Beam Milling on Preparation of Aluminum Thin Foils  

Energy Technology Data Exchange (ETDEWEB)

Focus Ion Beam (FIB) milling has greatly extended the utility of atom probe and TEM because it enables sample preparation with a level of dimensional control never before possible. Using FIB it is possible to extract the samples from desired and very specific locations. The artifacts associated with this sample preparation method must also be fully understood. In this work issues specifically relevant to the FIB milling of aluminum alloys are presented. After using the FIB as a sample preparation technique it is evident that gallium will concentrate in three areas of the sample: on the surface, on grain boundaries and at interphase boundaries. This work also shows that low energy Ar ion nanomilling is potentially quite effective for removing gallium implantation layers and gallium from the internal surfaces of aluminum thin foils.

2010-03-01

17

Repeat Stereotactic Radiosurgery for Acoustic Neuromas  

International Nuclear Information System (INIS)

Purpose: To evaluate the outcome of repeat stereotactic radiosurgery (SRS) for acoustic neuromas, we assessed tumor control, clinical outcomes, and the risk of adverse radiation effects in patients whose tumors progressed after initial management. Methods and Materials: During a 21-year experience at our center, 1,352 patients underwent SRS as management for their acoustic neuromas. We retrospectively identified 6 patients who underwent SRS twice for the same tumor. The median patient age was 47 years (range, 35-71 years). All patients had imaging evidence of tumor progression despite initial SRS. One patient also had incomplete surgical resection after initial SRS. All patients were deaf at the time of the second SRS. The median radiosurgery target volume at the time of the initial SRS was 0.5 cc and was 2.1 cc at the time of the second SRS. The median margin dose at the time of the initial SRS was 13 Gy and was 11 Gy at the time of the second ...

2010-02-01

18

The decay of a new nuclide: "7"1Br  

International Nuclear Information System (INIS)

The decay of mass-separated samples of the previously unknown nuclide "7"1Br have been investigated by means of the Chalk River on-line isotope separator. Eleven #gamma#-transitions were assigned to the decay of this nuclide and its half-life was measured to be 21.4 +- 0.6 s. A simple decay scheme for "7"1Br has been constructed incorporating six levels in its daughter, "7"1Se. The half-life of the first excited state in "7"1Se was measured to be 5.5 +- 1.0 #mu#s and the transition from this state to the ground state was found to be highly converted. Systematic trends in the level schemes of "6"7Zn, "6"9Ge and "7"1Se are investigated. (orig.).

1981-07-20

19

Facial osteomyelitis as complication of chronic sinusitis in hemophiliac-AIDS patients - scintigraphic evaluation with technetium-99m-MDP and Gallium-67; Osteomielitis da face como complicacao de sinusite cronica em hemofilicos aideticos - avaliacao cintilografica com {sup 99m} Tc-MDP e {sup 67} Ga  

Energy Technology Data Exchange (ETDEWEB)

In the paper six cases of facial osteomyelitis as a complication of chronic sinusitis in hemophiliac-AIDS patients are reported. Osteomyelitis was suggested by an increasing of erythrocyte sedimentation rate. The diagnosis was confirmed by a positive {sup 99m} Tc MDP scintigraphy. The patients were submitted to clinical treatment. The erythrocyte sedimentation rate and 67-gallium citrate scans were used in the follow-up of the therapy. Three patients had negative gallium after three weeks of organism-specific antibiotic therapy; in two patients the gallium scintigraphy remained positive. One patient did not undergo the radionuclide scan for this clinical conditions. These results suggest that MDP scans showed higher sensitivity and specificity in detection of bone disease in chronic sinusitis. Gallium scans appeared to be valuable tool in the follow-up of the infection. There are no reports in the ...

1997-01-01

20

Characterization of tris(N-substituted-2-methyl-3-hydroxy-4-pyridinonato)technetium(IV) cations  

Energy Technology Data Exchange (ETDEWEB)

A burgeoning interest in technetium coordination chemistry has been spurred by its widespread use in nuclear medicine. Recent focus has been on the design and preparation of new technetium complexes, the lipophilicity, polarity, and overall charge of which can be readily altered by simple substitutions in the molecular framework of the ligand in order to optimize the biodistribution and target specific organs. Examples are cationic (Cardiolite) and neutral (Ceretec) technetium complexes, used as myocardial and brain imaging agents, respectively. The authors have been pursuing a continuing study of tris(3-hydroxy-4-pyridinonato)gallium and -indium complexes that are water soluble, are hydrolytically stable, and are of varying lipophilicity and neutral charge. Studies of in vivo in rabbits and mice have revealed that several of these cationic complexes may be useful as morphologic kidney imaging agents, with [{sup 99m}Tc(pap){sub 3}]{sup +} ...

1994-11-23

21

Characterization of tris(N-substituted-2-methyl-3-hydroxy-4-pyridinonato)technetium(IV) cations  

International Nuclear Information System (INIS)

A burgeoning interest in technetium coordination chemistry has been spurred by its widespread use in nuclear medicine. Recent focus has been on the design and preparation of new technetium complexes, the lipophilicity, polarity, and overall charge of which can be readily altered by simple substitutions in the molecular framework of the ligand in order to optimize the biodistribution and target specific organs. Examples are cationic (Cardiolite) and neutral (Ceretec) technetium complexes, used as myocardial and brain imaging agents, respectively. The authors have been pursuing a continuing study of tris(3-hydroxy-4-pyridinonato)gallium and -indium complexes that are water soluble, are hydrolytically stable, and are of varying lipophilicity and neutral charge. Studies of in vivo in rabbits and mice have revealed that several of these cationic complexes may be useful as morphologic kidney imaging agents, with ["9"9"mTc(pap)_3]"+ showing elevated ...

22

48 CFR 2452.239-71 - Information Technology Virus Security.  

Science.gov (United States)

... 2010-10-01 true Information Technology Virus Security. 2452...Clauses 2452.239-71 Information Technology Virus Security. As prescribed...the following clause: Information Technology Virus Security (FEB...

2010-10-01

23

48 CFR 1252.239-71 - Information technology security plan and accreditation.  

Science.gov (United States)

...2010-10-01 false Information technology security plan and accreditation...Clauses 1252.239-71 Information technology security plan and accreditation...following provision: Information Technology Security Plan and...

2010-10-01

24

WASTE SOLIDIFICATION BUILDING BENCH SCALE HIGH ACTIVITY WASTE SIMULANT VARIABILITY STUDY FY2008  

Energy Technology Data Exchange (ETDEWEB)

The primary objective of this task was to perform a variability study of the high activity waste (HAW) acidic feed to determine the impact of feed variability on the quality of the final grout and on the mixability of the salt solution into the dry powders. The HAW acidic feeds were processed through the neutralization/pH process, targeting a final pH of 12. These fluids were then blended with the dry materials to make the final waste forms. A secondary objective was to determine if elemental substitution for cost prohibitive or toxic elements in the simulant affects the mixing response, thus providing a more economical simulant for use in full scale tests. Though not an objective, the HAW simulant used in the full scale tests was also tested and compared to the results from this task. A statistically designed test matrix was developed based on the maximum molarity inputs used to make the acidic solutions. The maximum molarity inputs were: 7.39 HNO{sub 3}, 0.11618 ...

2009-03-20

25

Strategies for gallium removal after focused ion beam patterning of ferroelectric oxide nanostructures  

International Nuclear Information System (INIS)

As part of a study into the properties of ferroelectric single crystals at nanoscale dimensions, the effects that focused ion beam (FIB) processing can have, in terms of structural damage and ion implantation, on perovskite oxide materials has been examined, and a post-processing procedure developed to remove such effects. Single crystal material of the perovskite ferroelectric barium titanate (BaTiO_3) has been patterned into thin film lamellae structures using a FIB microscope. Previous work had shown that FIB patterning induced gallium impregnation and associated creation of amorphous layers in a surface region of the single crystal material some 20 nm thick, but that both recrystallization and expulsion of gallium could be achieved through thermal annealing in air. Here we confirm this observation, but find that thermally induced gallium expulsion is associated with the formation of gallium-rich ...

2007-01-24

26

Influence of Dopants on Characteristics of X-Ray Detectors Fabricated from Indium-, Gallium-, and Chlorine-Doped Cadmium Telluride Single Crystals  

Science.gov (United States)

Counting characteristics of X-ray detectors fabricated from indium-doped, gallium-doped, and chlorine-doped CdTe have been investigated. The detectors fabricated from indium-doped and gallium-doped crystals showed radiation-induced polarization, namely, a progressive decrease of count rate with an increase of photon fluence in the high-photon-fluence region, while the detectors fabricated from chlorine-doped crystals did not. Results from current-voltage characteristics of the detectors indicated that the different counting characteristics of these detectors originated from the difference in internal electric fields in each detector.

1995-08-01

27

High bandgap window layer for GaAs solar cells and fabrication process therefor  

Science.gov (United States)

The specification describes a semiconductor solar cell and fabrication process therefor wherein a thin N-type gallium arsenide layer is deposited on a larger P-type substrate layer which is selected from the group of III-V ternary compounds consisting of aluminum phosphide antimonide, AlPSb, and aluminum indium phosphide, AlInP. P-type impurities are diffused from the substrate layer into a portion of the thin N-type gallium arsenide layer to form P-type region wherein which defines a PN junction in the thin gallium arsenide layer. Thus, the quantity of gallium arsenide required to provide this PN photovoltaic junction layer in the cell is minimized, and th P-type substrate serves as a high bandgap window layer for the cell. Such high bandgap of this window material is especially well suited for efficiently transmitting the blue spectrum of sunlight to the PN junction, thus enhancing the power ...

1979-05-29

28

Gallium Disrupts Iron Uptake by Intracellular and Extracellular Francisella Strains and Exhibits Therapeutic Efficacy in a Murine Pulmonary Infection Model ?  

UK PubMed Central (United Kingdom)

Francisella tularensis requires iron (Fe) for growth, but the biologic sources of Fe for this organism are largely unknown. We found that Francisella sp. growing in...Full Text Available

2010-01-01

29

A Gallium Arsenide MESFET Operational Amplifier for Use in ...  

Science.gov (United States)

... 19. AmSTR.ACT (Continuq 9n =usff i En " Adentity by bo nwnb Agallumarsemoe t(a.") MEtFET ... 2%ITE 4T (Include Area Code) InghE SMO ...

1993-12-01

30

Investigation of Behaviorally Modified Rats for Use in ...  

Science.gov (United States)

... F;qure Title phge 20 Rat B Spectral Density Measurements TNT Stimuli 70 21 Rat B Spectral Density Measurements Neutral Stimuli 71 ...

1981-12-01

32

New approach for in vivo detection of insulitis in type I diabetes: activated lymphocyte targeting with "1"2"3I-labelled interleukin 2  

International Nuclear Information System (INIS)

Insulitis is considered the histopathological hallmark of type I diabetes. In the non-obese diabetic (NOD) mouse, diabetes has never been observed in the absence of insulitis. The in vivo detection of insulitis could be of relevance for early prediction of diabetes. As approximately 15% of islet-infiltrating lymphocytes express interleukin 2 receptors, the authors have labelled recombinant inter-leukin 2 with "1"2"3I and used this radiopharmaceutical to detect insulitis by gamma camera imaging. The authors studied 71 prediabetic NOD and 27 normal Balb/c mice. Labelled #alpha#-lactalbumin was used as the control protein. In the first set of experiments the tissue distribution of radiolabelled interleukin 2 in isolated organs from animals sacrificed at different time points was studied. Higher radioactivity was detected in the pancreas of NOD mice injected with labelled interleukin 2, as compared to NOD mice receiving labelled #alpha#-lactalbumin. In another set of ...

1994-01-01

33

Structural properties of Cu(In,Ga)Se2 thin films prepared from chemically processed precursor layers  

International Nuclear Information System (INIS)

We have developed a chemical process for incorporating copper into indium gallium selenide layers with the goal of creating a precursor structure for the formation of copper indium gallium diselenide (CIGS) photovoltaic absorbers. Stylus profilometry, EDX, Raman spectroscopy, XRD and SIMS measurements show that when indium gallium selenide layers are immersed in a hot copper chloride solution, copper is incorporated as copper selenide with no increase in the thickness of the layers. Further measurements show that annealing this precursor structure in the presence of selenium results in the formation of CIGS and that the supply of selenium during the annealing process has a strong effect on the morphology and preferred orientation of these layers. When the supply of Se during annealing begins only once the substrate temperature reaches ? 400 deg. C , the resulting CIGS layers are smoother and have more pronounced preferred ...

2009-02-02

34

Scintiscanning with aerosols of "9"9Tc"m DTPA in the diagnostic strategy for pneumocystosis in aids patients  

International Nuclear Information System (INIS)

Pulmonary clearance of an aerosol of "9"9Tc"m DTPA was measured in 21 non-smoking AIDS and pneumocystosis patients. The results were compared with those of pulmonary scintiscanning with gallium. All the patients exhibited increased clearance, evidence of a considerable alteration in alveolar permeability. This increase was also observed in patients with normal chest X-rays and normal blood gases. The average clearance in these patients was 6 #+-# 2% min"-"1 as compared with a normal 1.1 #+-# 0.3% min"-"1. Conversely, only four out of eight patients with normal chest X-rays had abnormal gallium scans. Clearance returned to normal after recovery. Measurement of DTPA clearance appears to be a very sensitive indicator for the detection and follow-up of pneumocystosis. However, it is not very specific since it can be increased by tobacco poisoning, drug abuse and the presence of lymphocytic alveolitis. An examination with normal findings can ...

1988-08-15

35

High-efficiency solar cell and method for fabrication  

Science.gov (United States)

A high-efficiency 3- or 4-junction solar cell is disclosed with a theoretical AM0 energy conversion efficiency of about 40%. The solar cell includes p-n junctions formed from indium gallium arsenide nitride (InGaAsN), gallium arsenide (GaAs) and indium gallium aluminum phosphide (InGaAlP) separated by n-p tunnel junctions. An optional germanium (Ge) p-n junction can be formed in the substrate upon which the other p-n junctions are grown. The bandgap energies for each p-n junction are tailored to provide substantially equal short-circuit currents for each p-n junction, thereby eliminating current bottlenecks and improving the overall energy conversion efficiency of the solar cell. Additionally, the use of an InGaAsN p-n junction overcomes super-bandgap energy losses that are present in conventional multi-junction solar cells. A method is also disclosed for fabricating the high-efficiency 3- or 4-junction solar cell by ...

1999-08-31

36

Detection of abnormalities in febrile AIDS patients with In-111-labeled leukocyte and Ga-67 scintigraphy  

International Nuclear Information System (INIS)

Thirty-six patients with acquired immunodeficiency syndrome (AIDS), who were febrile but without localizing signs, underwent indium-111 leukocyte scintigraphy 24 hours after injection of labeled white blood cells (WBCs) and were restudied 48 hours after injection of gallium-67 citrate. Fifty-six abnormalities were identified as possible sources of the fever; 27 were confirmed with biopsy. Of these 27, 15 were identified only on In-111 WBC scans (including colitis, sinusitis, and focal bacterial pneumonia); six, only on Ga-67 scans (predominantly Pneumocystis carinii pneumonia and lymphadenopathy); and six, on both studies (predominantly pulmonary lesions). In-111 WBC scanning revealed 21 of 27 abnormalities (78%) and gallium scanning, 12 of 27 (44%). If only one scintigraphic study has been performed, particularly with Ga-67, a significant number of lesions would not have been detected. The authors believe radionuclide evaluation of the febrile ...

37

New Variant of CTX-M-Type Extended-Spectrum ?-Lactamases, CTX-M-71, with a Gly238Cys Substitution in a Klebsiella pneumoniae Isolate from Bulgaria?  

UK PubMed Central (United Kingdom)

A single Klebsiella pneumoniae strain isolated in a Bulgarian hospital was found to produce CTX-M-71, a new CTX-M variant characterized by one amino acid substitution...Full Text Available

2009-10-01

38

L-subshell ionisation of [sub 71]Lu, [sub 73]Ta and [sub 79]Au by 1. 5-4. 5 MeV alpha particles  

Energy Technology Data Exchange (ETDEWEB)

The L X-rays of [sub 71]Lu, [sub 73]Ta and [sub 79]Au were produced by 1.5-4.5 MeV alpha particle bombardment. The emitted L[sub [alpha

1992-11-01

39

High-spin structure of odd $^{71-81}$Ga isotopes with shell model  

CERN Document Server

The recently measured experimental data of Argonne National Laboratory for high-spin states in neutron-rich $^{71,73,75,77}$Ga isotopes have been interpreted in the framework of large-scale shell model. Calculations have been performed in $f_{5/2}pg_{9/2}$ model space with two recent effective shell model interactions, JUN45 and jj44b. We also predict high-spin states for $^{79,81}$Ga, where very little is known experimentally. The calculated results show that existence of band structure built on top of the 3/2$^-$, 5/2$^-$ and 9/2$^+$ levels in $^{71-77}$Ga. The collective structure reflected in experimental data is not well reproduced in calculated values. The calculated positive parity states in $^{71,73,75}$Ga are higher in energy in comparison to experimental finding, while for $^{77,79}$Ga, the positive parity states are in better agreement. Both the interactions predict, leading configuration of $\\pi(f_{5/2}^3)$ and ...

2011-01-01

40

Spectroscopy of gadolinium gallium garnet crystals doped with Y b3+ revisited  

International Nuclear Information System (INIS)

The optical spectroscopy measurements of gadolinium gallium garnet (GGG) crystals doped with Yb show evidence of the presence of non-equivalent optical centers with very similar radiative decay rates. The energy level schemes of those centers have been determined on the basis of optical absorption, luminescence and Raman experiments. Crystal field fitting resulted in two sets of slightly different crystal field parameters for two non-equivalent Yb centers. Both sets of parameters describe perfectly the experimentally detected Y b3+ energy levels. Correlation between systematic trends in the experimental energy level schemes and crystal field parameters is discussed.

2010-06-30

41

Ion beam induced charge imaging of epitaxial GaN detectors  

Energy Technology Data Exchange (ETDEWEB)

We report the use of ion beam induced charge imaging to characterise the charge signal uniformity of epitaxial gallium nitride radiation detectors. The detectors were fabricated from 2 {mu}m thick semi-insulating gallium nitride, grown by MOCVD on a sapphire substrate. A carrier concentration of 1.4x10{sup 15} cm{sup -3} was measured using capacitance-voltage measurements. Ion beam induced charge imaging was carried out with a 2 MeV alpha particle beam focussed to a 3 {mu}m diameter and raster scanned across the device. The resulting ion beam images show excellent charge signal uniformity in this material with no evidence of material defects or polycrystalline structure on the micrometer length scale. No evidence of charge signal trapping was observed in these devices.

2004-09-21

42

Feasibility investigations of growing and characterizing gallium arsenide crystals in ribbon form. Quarterly progress report 1 Jan-31 Mar 1975  

International Nuclear Information System (INIS)

The feasibility of continuous production of gallium arsenide ribbon single crystals, by passage of a molten zone through boron-oxide encapsulated GaAs feedstock, is being investigated. Polycrystalline GaAs ribbons have been grown in graphite boats by passage of a wide zone through B2O3-encapsulated feed-stock, confined by a quartz cover plate. Failure to remove the encapsulant above its glass transition temperature, however, resulted in cracking of the ribbons on cooling to room temperature. In order to study the crucial zone melting step in isolation from the encapsulation steps of the continuous process, a constrained-zone melting apparatus has been constructed in which the boron oxide serves only as a sealant to suppress arsenic vaporization. Large grained polycrystalline samples have been produced with this apparatus.

44

Constraints on target chamber first wall and target designs that will enable NIF debris shields to survive  

CERN Document Server

Constraints on target chamber first wall and target designs that will enable NIF debris shields to survive

1999-01-01

45

Wetlands remediation of gallium arsenide: A case study describing a site-specific exposure assessment  

Energy Technology Data Exchange (ETDEWEB)

Based upon the existing regulatory cleanup criteria, remediation of this wetlands was proposed by the New Jersey Department of Environmental Protection and Energy (NJDEPE). This remedial process would have totally destroyed a thriving Old Field Wetlands. Site-Specific evaluation of the chemicals of potential concern (CPC), remaining source areas, potential environmental fate and transport (EF and T), toxicology (including oral absorption and bioaccumulation) and potential land use scenarios were conducted. It was determined that although the analytical chemistry data reported soil concentrations of arsenic, the compound used by the facility and discharged to the wetlands sediments was in fact gallium arsenide. Secondly, all remaining source areas and hot spots had previously been remediated. Vertical migration to soils had not progressed past a depth of 3 feet and groundwater/surface water did not contain significantly elevated concentrations of ...

1994-12-31

46

Transfer of chemical elements to breast milk  

International Nuclear Information System (INIS)

The project is intended to yield information on the transfer factors describing the transfer of ingested radionuclides to breast milk for the following elements: antimony, cerium, chromium, cobalt, gallium, lanthanum, molybdenum, niobium, radium, ruthenium, silver, thorium, titanium, and uranium. Those yet unknown or poorly known transfer factors are required in order to be able to develop a reliable model for description and assessment of the transfer of the radionuclides and the possibly resulting hazardous doses to infants, and for subsequent formulation of recommendations for radiological protection of the population. (orig./CB)

1999-08-01

47

The AMOS cell - An improved metal-semiconductor solar cell  

Science.gov (United States)

A new fabrication process is being developed which significantly improves the efficiency of metal-semiconductor solar cells. The resultant effect, a marked increase in the open-circuit voltage, is produced by the addition of an interfacial layer oxide on the semiconductor. Cells using gold on n-type gallium arsenide have been made in small areas (0.17 sq cm) with conversion efficiencies of 15% in terrestrial sunlight.

1975-01-01

48

Quantitative bone and 67Ga scintigraphy in the differentiation of necrotizing external otitis from severe external otitis  

Energy Technology Data Exchange (ETDEWEB)

Qualitative technetium Tc 99m bone scintigraphy using phosphate compounds and gallium 67 scintigraphy were described as a helpful means in diagnosing necrotizing external otitis (NEO). They were, however, claimed to be nonspecific. Quantitative Tc 99m methylene diphosphonate bone scintigraphy and gallium 67 scintigraphy were performed in eight patients with NEO and in 20 patients with severe external otitis, in order to prove usefulness of scintigraphy in the diagnosis of NEO. Ratios of lesion to nonlesion for bone scintigraphy were 1.67 {plus minus} 0.16 in patients with NEO and 1.08 {plus minus} 0.09 in patients with severe external otitis, and for gallium 67 scintigraphy they were 1.35 {plus minus} 0.24 in NEO patients and 1.05 {plus minus} 0.03 in patients with severe external otitis. There was no difference in uptake between diabetic patients with severe external otitis and nondiabetic patients. The scintigraphic ...

1991-06-01

49

Quantitative bone and 67Ga scintigraphy in the differentiation of necrotizing external otitis from severe external otitis  

International Nuclear Information System (INIS)

Qualitative technetium Tc 99m bone scintigraphy using phosphate compounds and gallium 67 scintigraphy were described as a helpful means in diagnosing necrotizing external otitis (NEO). They were, however, claimed to be nonspecific. Quantitative Tc 99m methylene diphosphonate bone scintigraphy and gallium 67 scintigraphy were performed in eight patients with NEO and in 20 patients with severe external otitis, in order to prove usefulness of scintigraphy in the diagnosis of NEO. Ratios of lesion to nonlesion for bone scintigraphy were 1.67 #+-# 0.16 in patients with NEO and 1.08 #+-# 0.09 in patients with severe external otitis, and for gallium 67 scintigraphy they were 1.35 #+-# 0.24 in NEO patients and 1.05 #+-# 0.03 in patients with severe external otitis. There was no difference in uptake between diabetic patients with severe external otitis and nondiabetic patients. The scintigraphic studies were also evaluated using a ...

50

Breakdown electroluminescence spectra in structures based on the solid solutions Ga/sub 1-x/Al/sub x/P(As)  

Energy Technology Data Exchange (ETDEWEB)

The authors investigate the breakdown luminescence spectra in reverse-biased p-n heterojunctions based on gallium and aluminum phosphides and arsenides for the purpose of determining their behavior as lasing and photodetection materials. Data are given on temperature coefficients, band gap structure, bremsstrahlung, hot carrier mobility and photon emission, and transition and recombination parameters.

1987-08-01

51

Atlas of nuclear medicine imaging  

Energy Technology Data Exchange (ETDEWEB)

An exhaustive compendium of normal and abnormal imaging is presented. The following systems and procedures are illustrated by over 2800 captioned illustrations: liver, spleen, and hepatobiliary imaging; perfusion and ventilation lung imaging; thyroid imaging; salivary gland imaging; bone imaging; brain imaging; radionuclide cisternography; blood flow studies; gallium imaging; nuclear cardiology; and renal imaging. Not included in the atlas are adrenal imaging procedures and emission computed tomography. (ERB)

1981-01-01

52

A shockproof container for the transport and storage of fragile or reactive target foils  

CERN Document Server

A shockproof container for the transport and storage of fragile or reactive target foils

1971-01-01

53

Morphology and Ultrastructure of Maternal Seed Tissues of Soybean in Relation to the Import of Photosynthate  

UK PubMed Central (United Kingdom)

Cytological observations were made on developing seeds of soybean (Glycine max (L.) Merr. “Amsoy 71”) using scanning and transmission electron microscopy and light microscopy....Full Text Available

1981-05-01

54

Guman June, 1971 PCD-TR-71-3, FHR 3795 - NASA Technical Reports Server  

Science.gov (United States)

the network were assembled of custom 450 volt Aluminum electrolytic capacitors provided by the Mallory Capacitor Company. A comparison between theoretical ...

55

Transfer of chemical elements to breast milk; Transfer von Elementen in die Muttermilch  

Energy Technology Data Exchange (ETDEWEB)

The project is intended to yield information on the transfer factors describing the transfer of ingested radionuclides to breast milk for the following elements: antimony, cerium, chromium, cobalt, gallium, lanthanum, molybdenum, niobium, radium, ruthenium, silver, thorium, titanium, and uranium. Those yet unknown or poorly known transfer factors are required in order to be able to develop a reliable model for description and assessment of the transfer of the radionuclides and the possibly resulting hazardous doses to infants, and for subsequent formulation of recommendations for radiological protection of the population. (orig./CB) [German] Ziel des Projektes ist die Ermittlung von Transferfaktoren fuer den Uebergang von Radionukliden aus der Nahrung der Muetter in die Muttermilch fuer die Elemente Antimon, Cer, Chrom, Cobalt, Gallium, Lanthan, Molybdaen, Niob, Radium, Ruthenium, Silber, Thorium, Titan und Uran. Um die Exposition und damit die ...

1999-08-01

59

Computational Challenges in miRNA Target Predictions: To Be or Not to Be a True Target?  

UK PubMed Central (United Kingdom)

All microRNA (miRNA) target—finder algorithms return lists of candidate target genes. How valid is that output in a biological setting? Transcriptome analysis has proven to be a useful approach...Full Text Available

2009-01-01

60
61

RBS Characterization of Yttrium Iron Garnet Thin Films  

International Nuclear Information System (INIS)

Magnetic materials such as yttrium iron garnet (YIG) are of great importance for its magneto-optic properties and for their potential applications in the domain of optical telecommunications. The deposition of thin films of YIG, on quartz or GGG (gadolinium gallium garnet) substrate, was performed using radio frequency non reactive magnetron sputtering, followed by high temperature annealing which is needed to enhance the crystallinity of the layers. Rutherford backscattering spectrometry RBS was used to determine the thickness and stoichiometry of the performed layers in order to investigate correlations between growth conditions and the quality of the final material. RBS measurements showed the influence of the deposition time and the temperature substrate on the film growth and its stoichiometry. (author)

2008-12-13

62

Photon deficient bone metastasis of hepatocellular carcinoma with avid gallium-67 uptake  

Energy Technology Data Exchange (ETDEWEB)

While bone metastases producing photon deficient defects on bone scintigraphy have previously been reported, this finding has not been emphasized for hepatocellular carcinoma (HCC). Furthermore, ''filling-in'' of such photon deficient defects with 67Ga at skeletal sites of metastatic HCC has not been described. In this case report, the combination of a photon deficient defect on bone scintigraphy and avid accumulation of 67Ga in this same area was of value in confirming the diagnosis of metastatic HCC.

1985-12-01

63

Phase diagrams  

International Nuclear Information System (INIS)

The description is presented of binary phase diagrams of titanium alloyed with the following elements: silver, aluminium, arsenic, gold, boron, barium, beryllium, bismuth, carbon, calcium, cadmium, cobalt, chromium, copper, iron, gallium, germanium, hydrogen, hafnium, indium, iridium, potassium, lithium, magnesium, manganese, molybdenum, nitrogen, sodium, niobium, nickel, oxygen, osmium, phosphorus, lead, palladium, platinum, plutonium, rhenium, lanthanium, cerium, preseodymium, neodymium, gadolinium, erbium, terbium, thulium, lutetium, rhodium, ruthenium, scandium, silicon, tin, strontium, tantalum, technetium, thorium, uranium, vanadium, tungsten, yttrium, ytterbium, zinc and zirconium.

64

Kinetic studies of alkali metal gallide decomposition in aqueous hydroxide solutions  

International Nuclear Information System (INIS)

Kinetics of decomposition of gallium and alkali metal intermetallic compounds in the systems LiGa-LiOH, LiGa-NaOH and LiGa-KON was studied in the temperature range of 40-80 deg C. It was ascertained that increase in temperature gives rise to increase in decomposition rate, whereas increase in hydroxide concentration involves the reaction deceleration. An assumption was made that the decomposition occurs with superimposing of two mechanisms, i.e. chemical and electrochemical decomposition. Basic kinetic characteristics of the process were determined - decomposition rate constant and current density

2002-01-01

65

Aluminium, gallium and indium complexing with methylthymol blue  

International Nuclear Information System (INIS)

Al, Ga and In complexing with methylthymol blue (H_6R) purified by gel filtration is studied. in the case of metal excess complexes with the ratio of components M:H_6R=2:1 with #lambda#=587(Al), 590(Ga) and 593 nm(In) appear. In the case of reacting agent excess complexes with the ratio of component 1:1 with #lambda#_m_a_x=480-490 (Al) and 480 nm(Ga, In) appear. The mechanism of complexing reactions is studied. Molar extinction coefficients and stability constants are calculated.

1988-01-01

66

Reasons for decision in the matter of TransCanada PipeLines Limited. Motifs de decision (relative a) TransCanada Pipelines Limited; Volume 3. Installations, exportations de gaz et demandes deposees en vertu de l'article 71  

Energy Technology Data Exchange (ETDEWEB)

TransCanada Pipelines Limited submitted an application to the National Energy Board for new facilities to increase natural gas deliveries to its domestic and export markets. The proposed facilities consist of 1,590 km of pipeline, 21 new compressor units and two new compressor stations. The total cost of the facilities was estimated at $2,408 million. The Board considered at the hearing 15 applications made pursuant to Part IV of the National Energy Board Act for gas exports at existing delivery points at Emerson and Niagra Falls as well as at proposed new delivery points at Chippawa and Iroquois, Ontario. Twelve of these applications were filed in support of TransCanada's facilities application. Five applications were also filed pursuant to section 71 of the National Energy Board Act for orders requiring TransCanada to receive, transport and deliver natural gas offered by the applicants and to provide adequate and suitable facilities to do so. A public ...

1991-04-01

67

Metadata - Global Change Master Directory (GCMD)  

Science.gov (United States)

... -70.920 1998 1999 CARA -46.803 -75.637 1999 CHCH -46.539 -71.734 1998 CUER - 51.634 -74.515 1998 1999 EDEN -49.120 -74.425 1998 ENGA -54.948 -70.779 1998 ...

68

Effective elastic constants of superlattices  

Energy Technology Data Exchange (ETDEWEB)

The effective elastic constants of a superlattice composed of layers of orthorhombic symmetry (with principal axes along the superlattice axis) are derived. These results generalize previous determinations for elastically isotropic layers (Rytov, Akust. Zh. 2, 71 (1956) (Sov. Phys.: Acoust. 2, 68 (1956))), but a completely different approach is used.

1985-05-15

69

Economic analysis of cogeneration. January 1976-December 1980 (citations from the Energy Data Base). Report for January 1976-December 1980  

Energy Technology Data Exchange (ETDEWEB)

This retrospective bibliography contains citations concerning economic analysis of the techniques and technology for cogeneration and the effects of government policies and industrial attitudes toward cogeneration. Combined energy systems and combined manufacturing/energy systems which utilize waste heat and waste products as well as traditional fuels are included. (Contains 71 citations, fully indexed and including a table of contents.)

1980-12-01

70

38 CFR 4.71a - Schedule of ratings-musculoskeletal system.  

Science.gov (United States)

...prosthesis) Anatomical loss near hip (preventing use of prosthesis) Anatomical loss or loss of use below elbow M Codes M-1 a, b, or c, 38 CFR 3.350 (c)(1)(i) L Codes L-1 d, e, f, or g, 38 CFR 3.350(b)...

2010-07-01

71

Targeting Prostate Cancer Cells In Vivo Using a Rapidly Internalizing Novel Human Single-Chain Antibody Fragment  

UK PubMed Central (United Kingdom)

Human antibodies targeting prostate cancer cell surface epitopes may be useful for imaging and therapy. The objective of this study was to evaluate the tumor targeting of an internalizing human...Full Text Available

2010-03-01

73

Isoform-level microRNA-155 target prediction using RNA-seq  

UK PubMed Central (United Kingdom)

Computational prediction of microRNA targets remains a challenging problem. The existing rule-based, data-driven and expression profiling approaches to target prediction are mostly approached from the...Full Text Available

2011-05-01

74

Delineating Bacteriostatic and Bactericidal Targets in Mycobacteria Using IPTG Inducible Antisense Expression  

UK PubMed Central (United Kingdom)

In order to identify novel high value antibacterial targets it is desirable to delineate whether the inactivation of the target enzyme will lead to bacterial death or stasis. This knowledge is particularly...Full Text Available

75

A thermal hydraulic investigation on ADSR liquid lead target  

Energy Technology Data Exchange (ETDEWEB)

Computational fluid dynamics(CFD) code FLUENT was used to simulate the thermal hydraulic processes occurring in conceptual design of the accelerator-driven subcritical reactor(ADSR) liquid lead target. The purpose of the analysis is to investigate the thermal hydraulic characteristics of liquid lead as ADSR target material with various target geometries and injection locations of proton beam. In the calculation analysis, the local temperature of the liquid lead target rises to the boiling temperature very rapidly. When the proton beam is injected from the bottom of the target system, the duration time to reach the boiling temperature is longer and the temperature distribution is flatter than other cases.

1998-05-01

76

Technology of GaAs metal-oxide-semiconductor solar cells  

Science.gov (United States)

The growth of an oxide interfacial layer was recently found to increase the open-circuit voltage (OCV) and efficiency by up to 60 per cent in GaAs metal-semiconductor solar cells. Details of oxidation techniques to provide the necessary oxide thickness and chemical structure and using ozone, water-vapor-saturated oxygen, or oxygen gas discharges are described, as well as apparent crystallographic orientation effects. Preliminary results of the oxide chemistry obtained from X-ray, photoelectron spectroscopy are given. Ratios of arsenic oxide to gallium oxide of unity or less seem to be preferable. Samples with the highest OVC predominantly have As(+3) in the arsenic oxide rather than As(+5). A major difficulty at this time is a reduction in OCV by 100-200 mV when the antireflection coating is vacuum deposited.

1977-01-01

77

Satellite power study (SPS) concept definition study (exhibit D). Volume 1: executive summary. Final report  

Energy Technology Data Exchange (ETDEWEB)

Efforts concentrated on updating of the Rockwell reference concept, definition of new system options, studies of special emphasis topics, further definition of the transportation system, and further program definition. The Rockwell reference satellite concept has a gallium arsenide (GaAs) solar cell array having flat concentrators with an effective concentration ratio of 1.83at end of life. Alternatives to this concept includes solid state power amplifiers or magnetrons for dc/RF conversion and multibandgap solar cells for solar to dc energy conversion. Two solid state concepts were studied. It was determined that the magnetron approach was the lowest mass and cost system.

1981-03-01

78

Numerical analysis of melting/solidification phenomena using a moving boundary problem analysis method X-FEM  

International Nuclear Information System (INIS)

A numerical analysis method for melting/solidification phenomena has been developed to evaluate a feasibility of several candidate techniques in the nuclear fuel cycle. Our method is based on the eXtended Finite Element Method (X-FEM) which has been used for moving boundary problems. Key technique of the X-FEM is to incorporate signed distance function into finite element interpolation to represent a discontinuous gradient of the temperature at a moving solid-liquid interface. Construction of the finite element equation, the technique of quadrature and the method to solve the equation are reported here. The numerical solutions of the one-dimensional Stefan problem, solidification in a two-dimensional square corner and melting of pure gallium are compared to the exact solutions or to the experimental data. Through these analyses, validity of the newly developed numerical analysis method has been demonstrated. (author)

2008-06-01

79

The response of small scale rigid targets to shallow buried explosive detonations  

British Library Electronic Table of Contents (United Kingdom)

Experimental and computational investigations were performed in order to better understand the mechanical response of rigid targets with various geometries to the detonation of shallow buried explosives. The motion of the targets was measured by use of high-speed digital video photography. This work involved flat targets, targets that were downwardly convex, and targets that were downwardly concave with explosive charges located at various positions beneath the targets. It was observed that, in general, angled hulls - whether downwardly concave or convex - tended to reduce the amount of momentum imparted to the center of mass of the targets. Computations were performed by use of an arbitrary Langrangian-Eulerian treatment in a nonlinear finite element code. A model based on quasi-static te...

2011-01-01

80

Targeting a Ruthenium Complex to the Nucleus with Short Peptides  

UK PubMed Central (United Kingdom)

In an effort to develop octahedral metal complexes as chemotherapeutic and diagnostic agents targeted to DNA, it is critical to optimize the properties of their cellular uptake. Appending d-octaarginine...Full Text Available

2010-05-15

81

Target stations and beam dumps for the CERN SPS  

International Nuclear Information System (INIS)

The design of the absorber blocks for internal and external dumping of the SPS proton beam is discussed. In addition, the external target stations for slow and fast extracted proton beams are described.

1977-03-16

82

Suitability of a New Plant Invader as a Target for Biological Control in Florida  

Science.gov (United States)

... L. Sutton. 2000. Is the aquatic weed hygrophila, Hygrophila polysperma (Polemoniales: Acanthaceae), a suitable target for classical biological ... ...

83

Nato SCI-12 on Camouflage Evaluation Workshop on Search and Target ...  

Science.gov (United States)

Nato SCI-12 on Camouflage Evaluation Workshop on Search and Target Acquisition The Netherlands, June 1999. Image Discrimination Models for Object Detection ...

84

FOR THIN AND THICK TARGETS - NASA Technical Report Server (NTRS)  

Science.gov (United States)

By W. Wayne Scott. Langley Research Center. SUMMARY. Thin- and thick-target bremsstrahlung spectra are presented for electron energies up to 7.0 MeV. ...

85

Target area chamber system design for the National Ignition Facility  

International Nuclear Information System (INIS)

The National Ignition Facility (NIF) is a proposed Department of Energy facility which will contribute to the resolution of important Defense Program and inertial fusion energy issues for energy production in the future. The NIF will consist of a laser system with 192 independent beamlets transported to a target chamber. The target chamber is a multi-purpose structure that provides the interface between the target and the laser optics. The chamber must be capable of achieving moderate vacuum levels in reasonable times; it must remain dimensionally stable within micron tolerances, provide support for the optics, diagnostics, and target positioner; it must minimize the debris from the x-ray and laser light environments; and it must be capable of supporting external neutron shielding. The chamber must also be fabricated from a low neutron activation material. The fusion reaction in the ...

1994-06-19

86

Target R and D at JAERI  

Energy Technology Data Exchange (ETDEWEB)

We proposed a solid and a mercury target concepts through the preliminary conceptual design. To feasible these concepts, analysis and experimental works are being carried out. This paper introduces an outline of present status of target R and D such as heat transfer augmentation experiments for the solid target, mercury flow tests with a loop of maximum flow rate of 15L/min, flow pattern measurements for a cold source moderator etc. as well as preliminary conceptual design works. (author)

1999-03-01

91

A He-gas Cooled, Stationary Granular Target  

CERN Document Server

In the CERN approach to the design of a neutrino factory, the repetition frequency of the proton beam is high enough to consider stationary solid targets as a viable solution for multi-MW beams. The target consists of high density tantalum spheres of 2 mm diameter which can efficiently be cooled by passing a high mass flow He-gas stream through the voids between the Ta-granules. Very small thermal shocks and stresses will arise in this fine grained structure due to the relatively long burst of 3.3 ms from the SPL-proton linac. In a quadruple target system where each target receives only one quarter of the total beam power of 4 MW, conservative temperature levels and adequate lifetimes of the target are estimated in its very high radiation environment. A conceptual design of the integration of the target into the magnetic horn-pion-collector is presented.

2003-01-01

92

Radon measurements in the Catalagzi Thermal Power Plant, Turkey  

Energy Technology Data Exchange (ETDEWEB)

The Catalagzi Thermal Power Plant (CTPP) is located at nearly 13 km North-east of Zonguldak city, which is located at the West Black Sea coast in Turkey. The middling products with high ash content of bituminous coals are used in this plant. Seasonal radon concentration measurements have been carried out by using CR-39 plastic track detectors in and around the CTPP. The annual average radon concentration has been found to vary from a minimum of 39.8 {+-} 28.9 Bq m{sup -3}) in the ash area to a maximum of about to 75.0 {+-} 15.7 Bq m{sup -3} in the service building of the power plant. The annual average radon concentration in the dwellings of the thermal power plant colony of the plant is 71.0 {+-} 33.4 Bq m{sup -3}. The effective dose has been found to vary from 0.38 to 0.71 mSv y{sup -1} with a mean value of 0.56 mSv y{sup -1}, which is lower than the effective dose values 3-10 mSv given as the range of action levels recommended by ...

2008-01-15

93

Corrosion kinetics and magnetite growth on carbon steels during hot conditioning of primary heat transport systems of PHWRs - a metallurgical analysis  

International Nuclear Information System (INIS)

The adherent magnetite film thickness, corrosion rate and the loose crud on the surface of carbon steel and other structural materials were evaluated by inserting the coupons in the two autoclaves connected to the two ends of the PHT systems of Indian PHWRs. This paper includes an analysis of the results obtained during the hot conditioning of TAPP-3 and 4, Kaiga-3 and 4, and RAPP-5. The system temperatures of 230 deg C to 260 deg C and the adherent magnetic thickness of 0.30 ?m to 0.75 ?m on the internal surface of carbon steel were achieved during the hot conditioning of these reactors. The time duration of termination of the hot conditioning ranged from 48 to 71 hours. The maximum magnetite film thickness of 0.75 ?m in 71 hours and temperature 260 deg C and a minimum thickness of 0.30 nm in 48 hours at 230 deg C were achieved during hot conditionings. The XRD analyses of hot conditioned carbon steel coupons showed that oxide film constitutes ...

2008-12-01

94

Clinical and tomographic aspects of macular microholes; Aspectos clinicos e tomograficos dos microburacos maculares  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To describe the clinical aspects and evaluate optical coherence tomography of macular microholes. Methods: Seven patients were assessed (8 eyes) with microholes of the macula. All patients underwent complete eye examination, fundus photography, fluorescent angiography and OCT-3 imaging. Results: Ages ranged from 26 to 69 years. Six patients were female (85.7%) and five of them had microhole in the right eye. The presenting symptom was decrease in visual acuity (71.3%) and central scotoma in (14.3%). Five eyes (71.4%) had no defects shown by fluorescent angiography. A defect in the outer retina was demonstrated in all eyes on optical coherence tomography. The lesions were nonprogressive. Conclusion: Macular microholes are small lamellar defects in the outer retina. The condition is nonprogressive, generally unilateral and compatible with good visual acuity. Fundus biomicroscopy associated with an optical coherence tomography are the ...

2009-07-01

95

The influence of pH on the structure of adenine monolayers adsorbed at Au(110)/electrolyte interfaces  

Energy Technology Data Exchange (ETDEWEB)

The pH of the solution is shown to significantly effect the reflection anisotropy spectroscopy (RAS) profiles of adenine adsorbed at Au(110)/electrolyte interfaces. At pH 12.8 the net adsorption is very weak due the formation of negative adenine ions in solution. The sensitivity of the RAS profiles to the pH of the solution is probably due to a change in the geometry of the adsorbed molecules caused by a disruption of the base stacking configuration that is adopted when adenine is adsorbed from solutions at pH 7.1. (Abstract Copyright [2010], Wiley Periodicals, Inc.)

2010-08-15

96

Study on reactor building structures using ultrahigh strength materials - Part 8: Results of mixed structure tests  

International Nuclear Information System (INIS)

The mixed structure of a nuclear reactor building is composed of SC-columns, S-beams, S-joints and PCa-panels. Following the last report (Part 7)[1], the main test results of the mixed structure, that is, the deformation mode, strain distribution and shear strength, are described. The S-joints using ultrahigh strength materials had no buckling nor shear slipping. The proposed mixed structure resisted the external horizontal forces under integrated uniformity among SC-columns, S-joints and PCa-panels. It could be confirmed that the mixed structure can be established. (author)

1993-08-15

97

Report of study group 7.1: natural gas in competition with electric power in industrial applications  

Energy Technology Data Exchange (ETDEWEB)

This report consists of three sections. The first section is a brief general overview of all the issues that impact the competition between natural gas and electricity in industrial applications. The second section of this report focus on the all the marketing issues and provides detail analysis of the status of these issues in Europe, Japan and United States. The third section of this report is a detail review of the current status of the competition between gas technologies and electro-technologies, it also make recommendation for developing new gas technologies. The fourth section is a contribution from M. Pettersson and S. Stenstroem, Sweden, on infrared dryers. (authors)

2000-07-01

98

Protecting the datacentre  

British Library Electronic Table of Contents (United Kingdom)

Data breaches, regularly in the news thanks to absent-minded employees or malicious hackers, are a real threat about which any company involved in the storing or transfer of data needs to be aware. And this isn't just about reputation and privacy - it has a real financial impact, too. In March 2010 the Ponemon Institute revealed that the cost of a data breach has risen for the third consecutive year. It found that the average data breach incident cost UK organisations @$1.9m or @$71 per record, an increase of 13% on 2009, and 18% on 2008. We all know how important it is to protect our data. Clearly, customers need to be choosy about whom they trust.

2011-01-01

99

In vitro study of plutonium in macrophages  

International Nuclear Information System (INIS)

An in vitro system for studying Pu uptake by, and removal from, macrophages was developed to provide data for the actinide therapy program. We have shown that "2"3"9PuO_2 particle uptake in vitro resembles the process in vivo with respect to the intracellular localization of phagocytized particles. At the end of 7 days of culture of Pu-loaded cells, 54% of the cells were viable even though 71% of the cells in the culture initially contained enough "2"3"9PuO_2 to deliver more than 53 intracellular #alpha#-disintegrations.

1977-05-01

100

Handling of sodium for the FFTF  

Science.gov (United States)

Based on the High Temperature Sodium Facility (HTSF) experience and the extensive design efforts for FFTF, procedures are in place for the unloading of the tank cars and for the fill of the FFTF reactor. Special precautions have been taken to provide safe handling and to accommodate contingencies in operation. These contingencies include special protective suits allowing personnel to enter and correct conditions arising from fill operations in the course of moving 7.71 x 10/sup 5/ kg (1.7 x 10/sup 6/ lbs) of sodium from the tank cars into the reactor vessel and its loop system.

1978-06-01

101

Decontamination of building surface using clay suspension  

Energy Technology Data Exchange (ETDEWEB)

The decontamination of the urban building surfaces, based on the covering of clay suspensions, has been studied. Contaminated samples for test purpose were prepared by application of radioactive solution which was extracted from the soil of 2 km zone of the Chernobyl Nuclear Power Plant(ChNPP). The cation converting conditions of clay suspensions were determined by the experiments of swelling and stability of the suspensions. According to the experimental results, the most effective clay suspension was the NH{sub 4}-type which had a 7.1 of decontamination factor(DF) on Cs and 4.5 of DF on total nuclides after 3 times covering on slate.

1994-07-01

102

A finite-dimensional fermionic TQFT  

CERN Document Server

A fermionic - based on Grassmann--Berezin calculus of anticommuting variables - topological quantum field theory (TQFT) is considered, mainly in three dimensions. It is defined for piecewise-linear manifolds and, for a given triangulation, deals only with a finite number of variables. Despite its simple nature, it can distiguish between lens spaces L(7,1) and L(7,2). And despite its origin from a kind of Reidemeister torsion, it does this without using nontrivial representations of the fundamental group. Also, symbolic calculations are presented giving strong evidence of existence of similar theory in four dimensions.

2011-01-01

103

Reasons for decision in the matter of TransCanada PipeLines Limited  

Energy Technology Data Exchange (ETDEWEB)

TransCanada Pipelines Limited submitted an application to the National Energy Board for new facilities to increase natural gas deliveries to its domestic and export markets. The proposed facilities consist of 1,590 km of pipeline, 21 new compressor units and two new compressor stations. The total cost of the facilities was estimated at $2,408 million. The Board considered at the hearing 15 applications made pursuant to Part IV of the National Energy Board Act for gas exports at existing delivery points at Emerson and Niagra Falls as well as at proposed new delivery points at Chippawa and Iroquois, Ontario. Twelve of these applications were filed in support of TransCanada's facilities application. Five applications were also filed pursuant to section 71 of the National Energy Board Act for orders requiring TransCanada to receive, transport and deliver natural gas offered by the applicants and to provide adequate and suitable facilities to do so. A public ...

1991-04-01

104

PROBABILITY OF FAILURE OF THE TRUDOCK CRANE SYSTEM AT THE WASTE ISOLATION PILOT PLANT (WIPP)  

Energy Technology Data Exchange (ETDEWEB)

This probabilistic analysis of WIPP TRUDOCK crane failure is based on two sources of failure data. The source for operator errors is the report by Swain and Guttman, NUREG/CR-1278-F, August 1983. The source for crane cable hook breaks was initially made by WIPP/WID-96- 2196, Rev. O by using relatively old (1970s) U.S. Navy data (NUREG-0612). However, a helpful analysis by R.K. Deremer of PLG guided the authors to values that were more realistic and more conservative, with the recommendation that the crane cable/hook failure rate should be 2.5 x 10-6 per demand. This value was adopted and used. Based on these choices a mean failure rate of 9.70 x 10-3(1/yr) was calculated. However, a mean rate by itself does not reveal the level of confidence to be associated with this number. Guidance to making confidence calculations came from the report by Swain and Guttman, who stated that failure data could be described by lognormal distributions. This is in agreement with the widely use d reports ...

2000-05-01

105

Self-assessment of current knowledge in nuclear medicine (second edition)  

Energy Technology Data Exchange (ETDEWEB)

In this updated second edition, the order of contents of the textbook has been reorganized. It has been divided into main parts: Basic Science and Clinical Nuclear Medicine. Basic Science, Part I, encompasses basic physics, radiation protection, interaction of radiation with matter and radiation detection, imaging, nuclear pharmacy, and radiation biology. Part II, Clinical Nuclear Medicine, covers the central nervous system, bone, gastroenterology (liver/spleen), cardiovascular system, pulmonary system, genitourinary system, thyroid and endocrine systems, gallium studies, radioassay, hematology, and therapy. The total number of pages of the current edition is increased to 250 from the 213 of the first edition but there are fewer questions because those in the basic science area have been carefully selected to 60 of the original 98 questions. Compared with the previous edition, there are two advantages in the current one: (1) the addition of explanatory answers; and ...

1981-01-01

106

Production of unsaturated nitriles using catalysts containing boron, gallium or indium  

Energy Technology Data Exchange (ETDEWEB)

This patent describes a process for the preparation of acrylonitrile or methacrylonitrile by the reaction of propylene or isobutylene, molecular oxygen and ammonia at a temperature of about 200/sup 0/ to 600/sup 0/C in the presence of an oxidation catalyst. The improvement consists of using as the oxidation catalyst an antimony-free catalyst having the atomic ratios described by the formula: X/sub a/A/sub b/C/sub c/Fe/sub d/Bi/sub e/Mo/sub 12/O/sub x/ wherein X is Ga, In or mixtures thereof; A is alkali metal; C is Ni, Co or mixture thereof; and wherein a is 0.01 to about 4; b is 0 to about 4; c and d are 0.01 to about 12; e is 0.01 to about 6; and x is a number sufficient to satisfy the valence requirements of the other elements present. In a process for the preparation of acrylonitrile or methacryloniotrile by the reaction of propylene or isobutylene, molecular oxygen and ammonia at a temperature of about 200/sup 0/ to 600/sup 0/C in the presence of an oxidation catalyst.

1988-08-23

107

Low concentration ratio solar array for low Earth orbit multi-100kW application. Volume 2: Drawings. Final Report  

Energy Technology Data Exchange (ETDEWEB)

A preliminary design effort directed toward a low concentration ratio photovoltaic array system based on 1984 technology and capable of delivering multi-hundred kilowatts (300 kW to 100 kW range) in low Earth orbit is described. The array system consists of two or more array modules each capable of delivering between 113 kW to 175 kW using silicon solar cells or gallium arsenide solar cells, respectively. The array module deployed area is 1320 square meters and consists of 4356 pyramidal concentrator elements. The module, when stowed in the Space Shuttle's payload bay, has a stowage volume of a cube with 3.24 meters on a side. The concentrator elements are sized for a geometric concentration ratio (GCR) of six with an aperture area of 0.5 meters x 0.5 meters. Drawings for the preliminary design configuration and for the test hardware that was fabricated for design evaluation and test are provided.

1982-07-01

108

Low concentration ratio solar array for low Earth orbit multi-100 kW application. Volume 1: Design, analysis and development tests. Final Report  

Energy Technology Data Exchange (ETDEWEB)

A preliminary design effort directed toward a low concentration ratio photovoltaic array system capable of delivering multihundred kilowatts (300 kW to 1000 kW range) in low earth orbit is described. The array system consists of two or more array modules each capable of delivering between 113 kW to 175 kW using silicon solar cells or gallium arsenide solar cells, respectively. The array module deployed area is 1320 square meters and consists of 4356 pyramidal concentrator elements. The module, when stowed in the Space Shuttle's payload bay, has a stowage volume of a cube with 3.24 meters on a side. The concentrator elements are sized for a geometric concentration ratio (GCR) of six with an aperture area of .25 sq. m. The structural analysis and design trades leading to the baseline design are discussed. It describes the configuration, as well as optical, thermal and electrical performance analyses that support the design and overall performance estimates ...

1983-07-01

109

Generation of ammonia plasma using a helical antenna and nitridation of GaAs surface  

International Nuclear Information System (INIS)

Using the ammonia (NH3) plasma generated by a helical antenna surrounded by two magnetic coils, the transition of the discharge mode from low-density plasma to high-density one was observed. At the transition, the emission intensities from the H atoms and NH radicals especially increased in the optical emission spectroscopy, while the intensities of the other emission lines also increased abruptly. The nitridation of gallium arsenide (GaAs) surface was performed using the high-density NH3 plasma, and the properties of the nitrided surface layer were compared with those nitrided by high-density N2 plasma using the same apparatus. From the spectroscopic ellipsometry measurements, the thickness of the nitrided layer was estimated to be 16-18 nm, while that by N2 was 3-4 nm. From the Ga 3d spectra, the contamination with oxygen in the nitridation layer by NH3 plasma was less than that by N2 plasma.

2003-05-15

110

Flux pinning and critical currents in A-15 superconductors  

Science.gov (United States)

The relationship between processing, microstructure, and properties was studied for A-15 compounds in multifilamentary composites produced by solid-state diffusion and in thin-film samples produced by vapor deposition. Grain sizes of A-15 superconducting compounds were measured by transmission electron microscopy of multifilamentary composites reacted at various temperatures. Critical current densities at 4.2 K and fields up to 6 T were found to be similar for niobium-tin, vanadium-gallium, and vanadium-silicon of the same grain size. Study of the Cu-V-Si phase diagram led to the production of improved multifilamentary vanadium-silicon conductors. The effects of various alloying elements on A-15 layers produced by solid-state diffusion were studied. The most promising new observation was that tantalum can be incorporated into niobium-tin reaction layers, leading to an enhancement of critical currents at high fields. The critical temperature of vapor-deposited, ...

1978-02-01

111

Fabrication of single nanofluidic channels in poly(methylmethacrylate) films via focused-ion beam milling for use as molecular gates  

International Nuclear Information System (INIS)

Focused-ion beam (FIB) milling provides rapid fabrication of individual cylindrical submicrometer channels with reproducible dimensions (#+-#5% diameters) through 8-#mu#m thick poly(methylmethacrylate) (PMMA) films. PMMA films are spincast on sacrificial Si carriers and sputter-coated with Au before the 30-kV gallium FIB milling process. By adding a trace amount of poly(ethyleneoxide) and poly(dimethylsiloxane) to the PMMA solution before casting, the films can be released for subsequent mounting in microfluidic devices to create hybrid microfluidic-nanofluidic multilevel architectures. In situ FIB sectioning demonstrates the smooth cylindrical surface within the pore. Placing a milled film in contact with an aqueous fluorescein solution fills the channel by capillary action, as verified by confocal fluorescence microscopy. Confocal fluorescence of dyed films reveals that the pores span the thickness of the PMMA film. Small arrays of channels with a defined number ...

2004-08-16

112

Diffusion mechanism of implanted Be in GaAs  

Energy Technology Data Exchange (ETDEWEB)

The transient enhanced diffusion of low and high dose implanted beryllium in undoped gallium arsenide during post-implant rapid thermal annealing in the temperature range of 700-900 C for 60-240 s has been studied and successfully simulated by the kick-out diffusion model, involving singly positively charged Be interstitials and doubly positively charged Ga self-interstitials. Using the ''plus one'' approach for Ga interstitial generation after implantation with the local Ga interstitial sink concept as well as the appropriate initial and boundary conditions for involved mobile species, and taking into account Fermi-level and built-in electric field effects, the obtained partial differential equations have been solved numerically by means of an explicit finite difference method. The thermal equilibrium concentrations and the diffusivities of Be and Ga interstitials, all as a function of temperature, have been deduced from the ...

2008-01-15

113

Variation in the Definition of Clinical Target Volumes for Pelvic Nodal Conformal Radiation Therapy for Prostate Cancer  

UK PubMed Central (United Kingdom)

PurposeWe conducted a comparative study of Clinical Target Volume (CTV) definition of pelvic lymph nodes by multiple GU radiation oncologists looking at the levels...Full Text Available

2009-06-01

114

Targeted nanoparticles that deliver a sustained, specific release of paclitaxel to irradiated tumors  

UK PubMed Central (United Kingdom)

To capitalize on the response of tumor cells to ionizing radiation, we developed a controlled-release nanoparticle drug delivery system using a targeting peptide that recognizes a radiation-induced...Full Text Available

2010-06-01

115

Targeted Deletion of Somatotroph Insulin-Like Growth Factor-I Signaling in a Cell-Specific Knockout Mouse Model  

UK PubMed Central (United Kingdom)

The role of IGF-I in the negative regulation of GH expression and release is demonstrated by in vitro and in vivo models; however, the targets and mechanisms of IGF-I...Full Text Available

2010-05-01

116

Specific genetic modifications of domestic animals by gene targeting and animal cloning  

UK PubMed Central (United Kingdom)

The technology of gene targeting through homologous recombination has been extremely useful for elucidating gene functions in mice. The application of this technology was thought impossible in the large...Full Text Available

117

Selective imaging of adherent targeted ultrasound contrast agents  

UK PubMed Central (United Kingdom)

The goal of ultrasonic molecular imaging is the detection of targeted contrast agents bound to receptors on endothelial cells. We propose imaging methods that can distinguish adherent microbubbles...Full Text Available

2007-04-21

118

National Newborn Screening Status Reports  

Science.gov (United States)

... detected (and reported) as a by-product of MRM screening (MS/MS) targeted by Law or Rule ... detected (and reported) as a by-product of MRM screening (MS/MS) targeted by Law or Rule ...

119

Inhibitors of RecA Activity Discovered by High-Throughput Screening: Cell-Permeable Small Molecules Attenuate the SOS Response in Escherichia coli  

UK PubMed Central (United Kingdom)

The phenomenon of antibiotic resistance has created a need for the development of novel antibiotic classes with non-classical cellular targets. Unfortunately, target-based drug discovery against...Full Text Available

2009-10-01

120

How DNA coiling enhances target localization by proteins  

UK PubMed Central (United Kingdom)

Many genetic processes depend on proteins interacting with specific sequences on DNA. Despite the large excess of nonspecific DNA in the cell, proteins can locate their targets rapidly. After initial...Full Text Available

2008-10-14

121

Evolutionary conservation of a microbody targeting signal that targets proteins to peroxisomes, glyoxysomes, and glycosomes  

UK PubMed Central (United Kingdom)

Peroxisomes, glyoxysomes, glycosomes, and hydrogenosomes have each been classified as microbodies, i.e., subcellular organelles with an electron-dense matrix that is bound by a single membrane. We investigated...Full Text Available

1991-09-01

122

Efficient use of accessibility in microRNA target prediction  

UK PubMed Central (United Kingdom)

Considering accessibility of the 3′UTR is believed to increase the precision of microRNA target predictions. We show that, contrary to common belief, ranking by the hybridization energy or by...Full Text Available

2011-01-01

123

Coordination of PAD4 and HDAC2 in the regulation of p53 target gene expression  

UK PubMed Central (United Kingdom)

Histone Arg methylation and Lys acetylation have been found to cooperatively regulate the expression of p53 target genes. Peptidylarginine deiminase 4 (PAD4) is an enzyme that citrullinates...Full Text Available

2010-05-27

124

Concurrent schedule control of human visual target fixations1  

UK PubMed Central (United Kingdom)

Operant conditioning techniques were applied to the study of how target fixations are controlled by the probability of signal occurrence. In a standard vigilance setting, gaze at three illuminable...Full Text Available

1973-11-01

125

Biphasic targeting and cleavage furrow ingression directed by the tail of a myosin II  

UK PubMed Central (United Kingdom)

Cytokinesis in animal and fungal cells utilizes a contractile actomyosin ring (AMR). However, how myosin II is targeted to the division site and promotes AMR assembly, and how the AMR coordinates with...Full Text Available

2010-12-27

126

Assessment of nodal target definition and dosimetry using three different techniques: implications for re-defining the optimal pelvic field in endometrial cancer  

UK PubMed Central (United Kingdom)

Purposes1. To determine the optimal pelvic nodal clinical target volume for post-operative treatment of endometrial cancer. 2. To compare the DVH of different treatment planning...Full Text Available

127

Transfer of elements into mother's milk; Transfer von Elementen in die Muttermilch  

Energy Technology Data Exchange (ETDEWEB)

This research project aimed to determine the factors for the transfer of the elements silver (Ag), cerium (Ce), cobalt (Co), chrome (Cr), gallium (Ga), lanthanum (La), molybdenum (Mo), niobium (Nb), radium (Ra), ruthenium (Ru), antimony (sb), thorium (Th), titanium (Ti) and uranium (U) from food into the mother's milk. This factors will be used as a basic to check and derive activity values for the contamination of food and for radiation protection at working places of suckling women. For this purpose 19 mothers collected samples daily (2-8 weeks), using the duplicate method, of all the food they consumed as well as of their milk. After microwave-assisted digestion the element contents were analysed by mass-spectroscopy with inductive coupled plasma (ICP-MS). The results of the mothers who participate for more than 5 weeks were used to make a time lapse between the intake and transfer of the elements in the mothers milk visible. (orig.) [German] Ziel ...

2000-08-01

128

In vivo and in vitro evaluation of dota-lanreotide radiolabelled with gallium-67  

International Nuclear Information System (INIS)

One of the refinements of modern Nuclear Medicine is the capacity of providing dynamic and kinetics images of the administered radiopharmaceutical, reproducing its transport mechanism, action sites, receptor binding and excretion route. With the continues technological advances new radiopharmaceuticals have been developed in order to express higher specificity and with higher characters of affinity between receptor/complex. One radiopharmaceutical is formed by a reagent or bio molecule that has in its structure a radioisotope, that has the objectives of carrying it to the organs of affinity or to benign or malign tumoral process. Somatostatin inhibits the growing and proliferation of several tumoral cells. Somatostatin analogs bind to somatostatic receptors that are expressed in different kind of neoplasia DOTA-LANREOTIDE (DOTALAN) is an octapeptide analog to somatostatin. The interest of labeling the bio conjugate with gallium-67 in Nuclear Medicine comes from its ...

129

Gallium-67 activated charcoal: a new method for preparation of radioactive capsules for colonic transit study  

Energy Technology Data Exchange (ETDEWEB)

Indium-111 is currently the radionuclide of choice for colonic transit study. However, it is expensive and not available in many hospitals. Technetium-99m has been proposed for colonic transit study but the short half-life has limited its use. Gallium-67 citrate is inexpensive and available in most countries. Most importantly, it has a suitable half-life for colonic transit study. Attempts have been made in some studies to use {sup 67}Ga citrate to label activated charcoal, but the results have not been good because of poor stability. In this study, we successfully labelled activated charcoal with {sup 67}Ga citrate by adding alcohol and 5% glucose solution. To evaluate the in vitro stability, the {sup 67}Ga-activated charcoal was incubated in a milieu mimicking the intestinal content, containing lipase, trypsin and glycochenodeoxycholate at different pH values (6.0, 7.0, 7.4 and 8.0) and for different durations (0 h, 24 h, 48 h, 72 h and 96 h). For the in vivo ...

2003-06-01

130

Three-quasiparticle states in "1"7"7Ta  

International Nuclear Information System (INIS)

... transitions lutetium 175 target mev range 10-100 multipolarity neutrons parity

131

Terrorism Knowledge Base (TKB)  

Science.gov (United States)

... they assisted in the 2000 attack on the USS Cole? ... List the types of targets that ETA has attacked. ... was at least partially responsible for the attack. ...

2008-04-01

132

Surgical Counter-Terrorism: Targeting Individuals as an ...  

Science.gov (United States)

... Tanzania, and the attack on the USS COLE. ... vis another has no bearing on the legality of the attack. If the person attacked is a combatant, the use of ...

2003-02-03

133

Single-Walled Carbon Nanotubes Targeted to the Tumor ...  

Science.gov (United States)

... 1981. Retention of diphenyls, terphenyls, phenylalkanes and fluorene on graphitized thermal carbon black. Chromatographia 14:510-514. ...

2009-09-01

134

Review of Vaccinia Virus and Baculovirus Viability Versus ...  

Science.gov (United States)

... hazards. One study targeted the effects of common household disinfectants on virus inactivation (Butcher and Ulaeto, 2005). ...

2008-03-01

135

Production of polarized negative ion beams by collisional pumping  

Energy Technology Data Exchange (ETDEWEB)

The production of polarized negative ion beams by collisional pumping is described. Collisional pumping utilizes repeated charge changing collisions in a thick electron-spin-polarized gas or vapor target to form a polarized fast atom beam. The polarized fast atom beam is then partially converted into a polarized negative ion beam in a vapor target. Analysis is presented for a hydrogen beam passing through either a thick polarized H atom target or a thick polarized alkali target. Large polarizations and large currents may be possible.

1983-01-01

136

Production of polarized negative ion beams by ''collisional pumping''  

Energy Technology Data Exchange (ETDEWEB)

The production of polarized negative ion beams by ''collisional pumping'' is described. Collisional pumping utilizes repeated charge changing collisions in a thick electron-spin-polarized gas or vapor target to form a polarized fast atom beam. The polarized fast atom beam is then partially converted into a polarized negative ion beam in a vapor target. Analysis is presented for a hydrogen beam passing through either a thick polarized H atom target or a thick polarized alkali target. Large polarizations and large currents may be possible.

1984-03-01

137
139

Pairing effect in the nucleon transfer processes in quasi-elastic heavy ion scattering  

International Nuclear Information System (INIS)

... range krypton 86 reactions molybdenum 92 target probability quasi-elastic

1987-04-14

140

Market segmentation and targeting for real time pricing  

Energy Technology Data Exchange (ETDEWEB)

While there is growing interest in Real Time Pricing as a competitive tool, its adoption to date has been constrained by wariness on the part of many utilities and many of their customers. That wariness is not misplaced, for Real Time Pricing is not for everyone. In order for both utilities and their customers to benefit, the pricing system must be properly tailored for, and offered to, the appropriate audience. This paper discusses needs for identifying targets, implications of targeting of Real Time Pricing to various types of customers, and implications for design and marketing of such pricing systems. Examples from utility experiences are provided, and recommendations are offered for development of improved targeting of Real Time Pricing.

1996-03-01

141

Fragmentation of nuclei by particles and nuclei of intermediate and high energies  

Energy Technology Data Exchange (ETDEWEB)

The present state of investigations into the fragmentation of target nuclei by particles and nuclei of intermediate and high energies is reviewed.

1983-11-01

143

Electron-Induced Luminescence and X-Ray Spectrometer (ELXS) System for Life Detection  

Science.gov (United States)

The ELXS concept is a novel, portable, micro-instrument targeted for the detection of mineralogic

2002-01-01

144

Electromagnetic excitations in nuclei: From photon scattering to photo-dissociation  

International Nuclear Information System (INIS)

... 98 target molybdenum 99 niobium 91 photoneutrons photonuclear reactions

2006-03-20

145

Effect of improved target designs on the "2"3"8Pu production at the Fast Flux Test Reactor  

International Nuclear Information System (INIS)

This paper present the results of a series of calculations made to determine the "2"3"8Pu production potential of several advanced target assembly designs in the Fast Flux Test Facility (FFTF). These calculations show that by using advanced target designs the intimately mix the "2"3"7Np target material with an yttrium hydride moderator, the FFTF has the potential of producing up to 30 kg of high-quality "2"3"8Pu per year.

1991-11-10

146

Target space duality II: applications  

Energy Technology Data Exchange (ETDEWEB)

We apply the framework developed in Target space duality I: general theory. We show that both nonabelian duality and Poisson-Lie duality are examples of the general theory. We propose how the formalism leads to a systematic study of duality by studying few scenarios that lead to open questions in the theory of Lie algebras. We present evidence that there are probably new examples of irreducible target space duality.

2000-09-25

147

Gastrin releasing peptide (GRP) receptor targeted radiopharmaceuticals: A concise update  

Energy Technology Data Exchange (ETDEWEB)

The gastrin releasing peptide (GRP) receptor is becoming an increasingly attractive target for development of new radiolabeled peptides with diagnostic and therapeutic potential. The attractiveness of the GRP receptor as a target is based upon the functional expression of GRP receptors in several tumors of neuroendocrine origin including prostate, breast, and small cell lung cancer. This concise review outlines some of the efforts currently underway to develop new GRP receptor specific radiopharmaceuticals by employing a variety of radiometal chelation systems.

2003-11-01

148

Effluent reduction using pinch technology: Targets for reduction and capital costs for mass exchange networks  

Energy Technology Data Exchange (ETDEWEB)

This paper illustrates how the techniques developed by the authors for capital cost targeting of mass exchange networks can be applied to determination of capital investment targets for reduction in effluent for existing systems involving mass exchange. The results is an impact diagram which shows the relationship between effluent reduction and capital investment, indicating a region of limiting return on investment as well as the maximum possible reduction in effluent. (au)

1999-02-01

149

Development of a new secondary beam separator and a new gas-jet target at Kyushu University  

International Nuclear Information System (INIS)

In order to facilitate observations of low energy nuclear reactions, a new type recoil mass-separator together with a new gas-jet target system is being developed at the tandem accelerator facility in Kyushu University. The expected mass-resolving power of the separator is 220 for a solid angle of 10 msr and the practical thickness of the gas-jet target will exceed 0.1 atm#centre dot#cm for the light elements of H and He. (author).

1994-06-01

150

Detection device for high explosives  

Energy Technology Data Exchange (ETDEWEB)

A portable fiber optic detector that senses the presence of specific target chemicals by electrostatically attracting the target chemical to an aromatic compound coating on an optical fiber. Attaching the target chemical to the coated fiber reduces the fluorescence so that a photon sensing detector records the reduced light level and activates an appropriate alarm or indicator.

1992-01-01

151

A Liquid Parahydrogen Target for the Measurement of a Parity-violating Gamma Asymmetry in Polarized Neutron Capture on Protons  

Energy Technology Data Exchange (ETDEWEB)

A 16 l liquid parahydrogen target has been developed for a measurement of the parity-violating {gamma}-asymmetry in the capture of polarized cold neutrons on protons in the {rvec n} + p {yields} d + {gamma} reaction by the NPDGamma collaboration. The target system was carefully designed to meet the stringent requirements on systematic effects for the experiment and also to satisfy hydrogen safety requirements. The target was designed to preserve the neutron polarization during neutron scattering on liquid hydrogen (LH{sub 2}), optimize the statistical sensitivity to the {rvec n} + p {yields} d + {gamma} reaction, minimize backgrounds coming from neutron interaction with the beam windows of the target cryostat, minimize LH{sub 2} density fluctuations which can introduce extra noise in the gamma asymmetry signal, and control systematic effects. The target incorporates two mechanical ...

2010-05-01

152

48 CFR 952.226-73 - Energy Policy Act target group certification.  

Science.gov (United States)

...2010-10-01 2010-10-01 false Energy Policy Act target group certification...Acquisition Regulations System DEPARTMENT OF ENERGY CLAUSES AND FORMS SOLICITATION...Provisions and Clauses 952.226-73 Energy Policy Act target group...

2010-10-01

153

Selection of IFE target materials from a safety and environmental perspective  

International Nuclear Information System (INIS)

Target materials for inertial fusion energy (IFE) power plant designs might be selected for a wide variety of reasons including wall absorption of driver energy, material opacity, cost and ease of fabrication. While each of these issues are of great importance, target materials should also be selected based upon their safety and environmental (S and E) characteristics. The present work focuses on the recycling, waste management and accident dose characteristics of potential target materials. If target materials are recycled so that the quantity is small, isotopic separation may be economically viable. Therefore, calculations have been completed for all stable isotopes for all elements from lithium to polonium. The results of these calculations are used to identify specific isotopes and elements that are most likely to be offensive as well as those most likely to be acceptable in terms of their S and E ...

2001-05-21

154

Mode of action of membrane-disruptive lytic compounds from the marine dinoflagellate Alexandrium tamarense  

British Library Electronic Table of Contents (United Kingdom)

Certain allelochemicals of the marine dinoflagellate Alexandrium tamarense cause lysis of a broad spectrum of target protist cells but the lytic mechanism is poorly defined. We first hypothesized that membrane sterols serve as molecular targets of these lytic compounds, and that differences in sterol composition among donor and target cells may cause insensitivity of Alexandrium and sensitivity of targets to lytic compounds. We investigated Ca^2^+ influx after application of lytic fractions to a model cell line PC12 derived from a pheochromocytoma of the rat adrenal medulla to establish how the lytic compounds affect ion flux associated with lysis of target membranes. The lytic compounds increased permeability of the cell membrane for Ca^2^+ ions even during blockade of Ca^2^+ channels wit...

2011-01-01

155

An identification method of positron production in laser beam interaction with targets  

Energy Technology Data Exchange (ETDEWEB)

A simple electromagnetic transport system was constructed to identify very rare positrons produced in a powerful laser beam interaction with a target. Testing experiments were carried out with CO[sub 2]-laser (10[sup 12] W/cm[sup 2]) beam pulses ([tau] = 50 ns, f = 0.01 Hz) focused on the copper target, as well as with a 96 MeV alpha-particle beam irradiated carbon target. The results showed that the developed system could be effectively used for positron identification and evaluation of their energy by means of a time-of-flight method. The computerized system to deal with this problem, together with others related to the power laser beam interaction with targets, has been constructed. (orig.).

1992-10-01

156

Activation analysis of target debris in the national ignition facility  

International Nuclear Information System (INIS)

The modeling methods used to compute the neutron-induced activation of target and near-target materials in the NIF facility are presented. A detailed space and energy description of the neutron environment in the different materials is provided. A new capability has been developed to treat in a general way the activation of debris produced in an operational regime of yield and no-yield experiments. First calculations are addressed to analyze the activity of the debris into the target chamber. The contribution of the different components to activity, interior dose rates, and waste disposal rating (WDR) is determined. The importance of the activation coming from primary irradiation in the target, and from secondary irradiation in debris deposited onto the first wall is assessed. Finally, waste hazards of the activated debris when removed out of the chamber and stored are analyzed. (authors)

1999-09-12

157

[Improvement of the recognition probability about camouflage target based on BP neural network].  

Science.gov (United States)

Using static Michelson interferometer to get the spectrum information of measurement targets for spectrum identification, under the condition that the interference length is constant, the system can be optimized by BP neural network algorithm for the mixed spectral separation process. Thereby it can realize improving the recognition probability of camouflage target. Collecting the spectrum information in field of view (FOV) by the interferometer and linear array CCD detector, composing the set of mixed spectrum data, with known absorption spectrum of the material as a hidden layer of rules, it used BP neural network to separate the mixed spectrum data. Experiment with different distances, different combinations of mixed background spectrum as the initial data, using steel target (size: 1.5 m x 1.5 m) made of four kinds, the recognition probability of non-camouflage target is about 90% by BP neural ...

2010-12-01

158

Traffic and transport in the Dutch National Environmental Outlook 4; Verkeer en vervoer in de Nationale Milieuverkenning 4  

Energy Technology Data Exchange (ETDEWEB)

In the Fourth Dutch National Environmental Outlook (NMP, abbreviated in Dutch) of the National Institute of Public Health and the Environment (VROM), published in July 1997, possible future developments in the traffic and transport sector in the Netherlands are described for the period 1995-2020 and also evaluates present Dutch policies. NMP-4 also offers possible solutions for expected environmental problems. This report serves as a background document for the traffic and transport sector. With a view to present Dutch policies, the main conclusions drawn from the Outlook are that: (1) the policy targets for car and lorry use for 2010 will not be met, (2) the target for CO2 emissions from road transport for 2010 will not be met, (3) the NOx emission target for 2010 will be met for cars, but not for trucks, (4) the VOC emission target for 2010 will be met for cars, but not for trucks, and (5) the noise ...

1998-03-01

159

Trichoderma-fortified compost extracts for the control of choanephora wet rot in okra production  

British Library Electronic Table of Contents (United Kingdom)

The potential of water extracts produced from rice straw (RST) and empty fruit bunch of oil palm (EFB) composts fortified with Trichoderma harzianum for the control of Choanephora wet rot of okra caused by Choanephora cucurbitarum was studied under field conditions. Disease severity was lowest in plants treated with Trichoderma-fortified RST extracts (9.56%) with a disease index of 1, mancozeb (Dithane M-45 (2gl-1 of water), Trichoderma-fortified EFB compost extracts, extracts of RST and EFB, and an aqueous suspension of T. harzianum recorded disease severity values of 10.25%, 19.38%, 37.56%, 53.71% and 56.36%, with a disease index of 1, 1, 2, 3 and 3, respectively. There was a reduction of 85.04% in Choanephora wet rot severity on okra treated with Trichoderma-fortified RST extracts durin...

2008-01-01

160

Study of interaction between 7-(6-Br-2-benzthiazolylazo)-8-oxiquinoline-5-sulfonic acid and uranium (6), zinc (2) and manganese (2)  

International Nuclear Information System (INIS)

A new reagent 7-(6-Br-2-henzthiazolilazo)-8-oxyquinoline-5-sulphoacid has been studied spectrophotometrically. Dissociation constants have been determined in 50% acetone (pK_1=2.5 and pK_2=5.9) and 50% dioxane (pK_1=1.7 and pK_2=6.1) as well as molar extinction coefficients of the reagent dissociated form in the same solvents (71.1.10"3 and 72.4.10"3). The conditions have been studied of complexing the reagent with ions of uranium (6), zinc (2), and manganese (2) in 50% dioxane (pH 2.5-4.5) and the properties of the formed complexes.

1977-01-01

161

Structure analysis of cation selective Cr-goethite as protective rust of weathering steel  

International Nuclear Information System (INIS)

We have performed extended X-ray absorption fine structure (EXAFS) analysis for artificial Cr-goethite to elucidate the local structure around Cr in Cr-goethite. The spectra were obtained using synchrotron radiation X-rays at the Photon Factory in Tsukuba. The first shell contributions were isolated by Fourier filtering EXAFS data, and the inverse Fourier transformed single-shell data were analyzed using a curve fitting method. The results show that Cr is coordinated with (7#+-#1)O"2"- ions. The protective characteristics of the Cr-goethite protective rust layer on weathering steel can be interpreted in terms of the O"2"- coordination around Cr"3"+ resulting in the creation of negative fixed charge in the Cr-goethite particles. (author)

2005-02-01

162

Restauration of the Clinton site; Restauration du site Clinton  

Energy Technology Data Exchange (ETDEWEB)

Mining of copper and zinc took place at the Clinton Mine located in the Estrie region of Quebec between 1973 and 1975, during which time 115,000 tons of mineral were treated at the Solbec plant. In this poster presentation, the authors provided the background information pertaining to this mine and described the state in which it was in 1994. The pit was covered with good quality water, with a pH of 7,1 and copper and zinc content ranging between 0,1 and 0,6 mg/l, and iron ranging between 0,2 and 1,8 mg/l. The tailings basin drainage was found to have a pH of between 3,6 and 6,1. A program for the characterization of the site was implemented and the concept for the restauration of the Clinton site was developed and implemented. The work carried out at the site is discussed during this presentation as well as the monitoring taking place. 27 figs.

2000-07-01

163

Regional assessment of ambient volatile organic compounds from biopharmaceutical R&D complex  

British Library Electronic Table of Contents (United Kingdom)

Biopharmaceutical R&D complexes are major emission sources of volatile organic compounds (VOCs), which may pose potential health risks for staff on site and residents nearby. In this paper health risk assessments were performed for the VOCs in the ambient air of a typical biopharmaceutical R&D complex in China. Results showed halogenated and alkyl compounds were dominant components among 24 major VOCs from 9 selected sampling sites, inside or around the complex. The principal component analysis (PCA) indicated VOCs were generated predominantly from the biopharmaceutical research activities (factor 1 (F1), 71.6%) and traffic vehicles (factor 2 (F2), 15.4%), which were confirmed by contour maps of five selected VOCs (benzene, toluene, chlorobenzene, methylene chloride and n-hexane) simulated...

2011-01-01

164

Quantitative 1-123 IMP SPECT, MR imaging, and neuropsychologic testing in AIDS dementia  

International Nuclear Information System (INIS)

The authors have performed I-123 IMP single- photon emission CT (SPECT) brain imaging on seven mildly demented patients with acquired immunodeficiency syndrome (AIDS) and on seven normal subjects. Pixel-intensity histograms have been analyzed for the fraction of pixels in the lowest quartile of the intensity range. This fraction (F) averaged 17.7% (standard deviation [SD] = 4.3) in the AIDS group and 12.6 (SD = 4.7) in the normal group (P <.05). Regression analysis of neuropsychological testing (NPT) scores vs F yielded a correlation coefficient of.71. The presence or degree of atrophy did not correlate with F or NPT scores.

165

Phylogeography of rabies virus isolated from dogs in Brazil between 1985 and 2006  

British Library Electronic Table of Contents (United Kingdom)

To establish the phylogeographic relationships in rabies viruses in Brazil, we studied a dataset retrieved from GenBank consisting of 71 genetic sequences from the coding region of the N gene of rabies viruses isolated in dogs over a period of 22?years. The Bayesian Markov chain Monte Carlo method available in the BEAST package was used with the GTR+G+?4 evolutionary model in conjunction with the relaxed uncorrelated lognormal molecular clock model and an exponential growth tree prior. A discrete phylogeographic diffusion model was also analyzed using a standard continuous-time Markov chain viewed with Google Earth to provide a spatial projection of the diffusion of genetic lineages based on their phylogeographic relationships. The topology of the time and substitution phylogenetic trees a...

2011-01-01

166

Optimizing the emissions and diesel replacement on a dual fuel, two stroke bus engine  

Energy Technology Data Exchange (ETDEWEB)

Two natural gas/diesel dual fuel conversion systems for the Detroit Diesel 6V-71 transit bus engine were described. The basic concept of a dual fuel engine was to operate a diesel engine with both liquid fuel injection and a lean premixed gas mixture. The engine achieved high efficiency due to the high compression ratio typical of the diesel engine. Test results were obtained using three different calibrations on one engine. The objectives were to match existing engine performance with improved emissions and better overall fuel economics. Results showed that overall, engine conversion has both economic and emissions advantages over a straight diesel engine. However, the durability and in-use applicability of the system remains to be demonstrated with an in-bus demonstration project.. 3 tabs., 4 figs.

1995-12-31

167

Operation of the Wilsonville Advanced Coal Liquefaction R and D Facility, 1981. Annual report  

Science.gov (United States)

This report summarizes the 1981 operating and test data obtained at the six ton per day Advanced Coal Liquefaction Research and Development Facility in Wilsonville, Alabama. Special emphasis is placed on data accumulated during the fourth quarter of 1981. The Wilsonville R and D Facility was in operation 71% of 1981 (70% of the fourth quarter) with scheduled shutdowns accounting for 23% of the downtime (28% during the fourth quarter). Kentucky 9 coal from the Fies mine was processed in all runs conducted during 1981 (Runs 222 through 235). The hydrotreater (HTR) unit was brought on stream successfully in May 1981. The three process units of the Wilsonville facility were operated in a non-integrated mode during the second half of 1981. Significant data was obtained and is summarized.

1984-08-01

168

Novelty, preparation, characterization and enhancement of magnetic properties of Mn nanoferrites using safety binder (egg white)  

British Library Electronic Table of Contents (United Kingdom)

Nanocrystalline MnFe"2O"4 ferrite was prepared by using autocombustion technique (flash). The microstructure and magnetic properties are studied. The results of XRD and TEM clarified that, this ferrite is nanosized with particle size (39 nm). Magnetic measurements showed a ferromagnetic behavior with T"C = 613 K, the saturation magnetization M"s = 13.71 emu/g, remanent magnetization M"r = 0.1694 emu/g and, coercivity H"c = 25.6 Oe. Natural material, egg white used as an aqueous medium to extend prepare nanoparticles better than other chemical interesting materials.

2011-01-01

169

NUCLEAR SPECTROSCOPY OF NEUTRON-DEFICIENT Lu, Ta, AND Re ISOTOPES  

Science.gov (United States)

The systematic behavior of excited nuclear levels was studied with Lu (Z = 71), Ta (Z = 73), and Re (Z = 75) activities produced in the ORNL proton cyclotron. Conversion-electron data are presented for electron-capture decay of Lu/sup 170.174m/, Ta/sup 173-178/, and Re/sup 179.181/. Level schemes are proposed based on these and on previously published up 173.175-179/, tulated. The proper ties of odd-A nuclei in the strongly deformed region of odd-N numbers 95-107 are discussed in connection with predictions of Mottelson and Nilsson. Two activities, Lu/sup 174m/ and Re/sup 179/ ( es sufficiert t 20 min), are previously unreported. (auth)

1960-01-01

170

Media Choice in Environmental Information Dissemination for Solid Waste Management among Policy Formulators and Implementors: A Case Study of Oyo State, Nigeria  

British Library Electronic Table of Contents (United Kingdom)

Environmental information has been described as central to the issues of solid waste management and disposal. This study investigated the availability and accessibility of environmental information to the solid waste policy formulators and implementors with regard to the media/channels used for disseminating environmental information to the public. A descriptive survey design was adopted for the study. A purposive sampling technique was used to select the sample and the method produced 205 respondents that consisted of 185 Policy Implementors and 20 Policy Formulators. A total of 147 cases were finally analyzed, which included 16 Policy Formulators (80% of total sample) and 131 Policy Implementors (71% of total sample). Data collected were analyzed using descriptive statistics such as perc...

2009-01-01

171

Measurements and calculations of M-shell X-ray production in Er, Yb and Lu by 0.75-6 MeV He ions  

Energy Technology Data Exchange (ETDEWEB)

M-shell X-ray production cross sections for the light rare-earth elements of {sup 68}Er, {sup 7}Yb and {sup 71}Lu have been measured for incident {sup 4}He{sup +} ions in the energy range from 0.75 to 6 MeV. The measured X-ray production cross sections are compared to the predictions of the First Born approximation, the ECPSSR theory and the ECUSAR theory. A comparison of the ytterbium M-shell X-ray production cross sections with these theories is made for two different sets of fluorescence yields and Coster-Kronig factors that are further modified for multiple ionization.

2005-12-15

172

Lead, cadmium, chromium, cobalt, and copper in chicken feathers from Tuskegee, Alabama  

Energy Technology Data Exchange (ETDEWEB)

The feather has been widely used as a indicator tissue of metal exposure in birds. The feathers were collected from Tuskegee University poultry farm (TUPF) and Harrison Poultry farm (HPF) chicken and analyzed by Inductively Coupled Plasma Atomic Emission Spectroscopy for lead, cadmium, cobalt, chromium, and copper contaminations. The mean levels of lead, cadmium, cobalt, chromium, and copper in TUPF chicken were 3.67, 0.13, 12.23, 0.22, and 7.71 ppm, respectively, and in HPF chicken were 5.32, 0.096, 11.03, 0.15, and 8.06 ppm, respectively. The mean levels of these metals did not show any significant difference between TUPF and HPF chicken.

1994-12-31

173

Ionic conduction in polyether-based lithium arylfluorosulfonimide ionic melt electrolytes  

Energy Technology Data Exchange (ETDEWEB)

We report synthesis, characterization and ion transport in polyether-based ionic melt electrolytes consisting of Li salts of low-basicity anions covalently attached to polyether oligomers. Purity of the materials was investigated by HPLC analysis and electrospray ionization mass spectrometry. The highest ionic conductivity of 7.1 x 10{sup -6} S/cm at 30 deg. C was obtained for the sample consisting of a lithium salt of an arylfluorosulfonimide anion attached to a polyether oligomer with an ethyleneoxide (EO) to lithium ratio of 12. The conductivity order of various ionic melts having different polyether chain lengths suggests that at higher EO:Li ratios the conductivity of the electrolytes at room temperature is determined in part by the amount of crystallization of the polyether portion of the ionic melt.

2009-10-01

174

Ionic conduction in polyether-based lithium arylfluorosulfonimide ionic melt electrolytes  

International Nuclear Information System (INIS)

We report synthesis, characterization and ion transport in polyether-based ionic melt electrolytes consisting of Li salts of low-basicity anions covalently attached to polyether oligomers. Purity of the materials was investigated by HPLC analysis and electrospray ionization mass spectrometry. The highest ionic conductivity of 7.1 x 10-6 S/cm at 30 deg. C was obtained for the sample consisting of a lithium salt of an arylfluorosulfonimide anion attached to a polyether oligomer with an ethyleneoxide (EO) to lithium ratio of 12. The conductivity order of various ionic melts having different polyether chain lengths suggests that at higher EO:Li ratios the conductivity of the electrolytes at room temperature is determined in part by the amount of crystallization of the polyether portion of the ionic melt.

2009-10-01

175

Influences of poly(ether urethane) introduction on poly(ethylene oxide) based polymer electrolyte for solvent-free dye-sensitized solar cells  

International Nuclear Information System (INIS)

A poly(ether urethane) (PEUR)/poly(ethylene oxide) (PEO)/SiO2 based nanocomposite polymer is prepared and employed in the construction of high efficiency all-solid-state dye-sensitized nanocrystalline solar cells. The introduction of low-molecular weight PEUR prepolymer into PEO electrolyte has greatly enhance the electrolyte performance by both improving the interfacial contact properties of electrode/electrolyte and decreasing the PEO crystallization, which were confirmed by XRD and SEM characteristics. The effects of polymer composition, nano SiO2 content on the ionic conductivity and I3- ions diffusion of polymer-blend electrolyte are investigated. The optimized composition yields an energy conversion efficiency of 3.71% under irradiation by white light (100 mW cm-2).

2009-11-01

176

Influence of gamma-irradiation, growth retardants and coatings on the shelf life of winter guava fruits (Psidium guajava L.)  

British Library Electronic Table of Contents (United Kingdom)

Experiment was conducted to study the effect of gamma irradiation, growth retardants and coatings (coconut oil, mustard oil and liquid paraffin) on shelf life of winter guava fruits during storage. The results revealed that the superiority of coconut oil coating over other post harvest treatments. Physiological loss in weight (7.1%), marketable fruits retained over control (86.7%), total soluble solid (16.1%), ascorbic acid (195 mg/100 g pulp) and total sugar (10%) of fruit were positively influenced by coconut oil coating up to 12 days of storage. The treatment was found significantly effective in increasing the post harvest life of fruits for 12 days over control without adversely affecting the fruit quality. Coconut oil coating gave highest consumer acceptability while, maintaining suff...

2010-01-01

177

Grouping Synonyms by Definitions  

CERN Document Server

We present a method for grouping the synonyms of a lemma according to its dictionary senses. The senses are defined by a large machine readable dictionary for French, the TLFi (Tr\\'esor de la langue fran\\c{c}aise informatis\\'e) and the synonyms are given by 5 synonym dictionaries (also for French). To evaluate the proposed method, we manually constructed a gold standard where for each (word, definition) pair and given the set of synonyms defined for that word by the 5 synonym dictionaries, 4 lexicographers specified the set of synonyms they judge adequate. While inter-annotator agreement ranges on that task from 67% to at best 88% depending on the annotator pair and on the synonym dictionary being considered, the automatic procedure we propose scores a precision of 67% and a recall of 71%. The proposed method is compared with related work namely, word sense disambiguation, synonym lexicon acquisition and WordNet construction.

2009-01-01

178

Environmental Synergisms and Extinctions of Tropical Species  

British Library Electronic Table of Contents (United Kingdom)

Abstract: Environmental synergisms may pose the greatest threat to tropical biodiversity. Using recently updated data sets from the International Union for Conservation of Nature (IUCN) Red List, we evaluated the incidence of perceived threats to all known mammal, bird, and amphibian species in tropical forests. Vulnerable, endangered, and extinct species were collectively far more likely to be imperiled by combinations of threats than expected by chance. Among 45 possible pairwise combinations of 10 different threats, 69%, 93%, and 71% were significantly more frequent than expected for threatened mammals, birds, and amphibians, respectively, even with a stringent Bonferroni-corrected probability value (p= 0.003). Based on this analysis, we identified five key environmental synergisms in t...

2009-01-01

179

Endoscopic monitoring of infliximab therapy in Crohn's disease  

British Library Electronic Table of Contents (United Kingdom)

AbstractBackground: So far, infliximab (IFX) therapy for the treatment of Crohn's disease (CD) has generally been guided by clinical symptoms. Data on treatment response as ascertained by endoscopy in IFX therapy are scarce. The aims of this study were to measure the endoscopic response rate during IFX induction and maintenance therapy in luminal CD, and also evaluate the role of endoscopy in monitoring IFX therapy. Methods: Data obtained from 71 patients with active luminal CD and treated with IFX were analyzed retrospectively. The endoscopy findings were scored according to mucosal activity as: 0 (remission), 1-2 (mild), 3-4 (moderate), and 5-6 (severe). A positive endoscopic response was determined by a decrease in score of at least two points and mucosal healing was assigned a score of...

2011-01-01

180

Electronic structures of highly symmetrical compounds of f elements. XXXI. Simulation of the crystal field splitting pattern of (THF)_3Li(#mu#-Cl)Nd[N(SiMe_3)_2]_3  

International Nuclear Information System (INIS)

The absorption spectra of an unoriented single crystal of the title compound (1) have been measured at room and at low temperatures. Assuming a similar sequence of crystal field (CF) levels as for the previously analyzed Nd[N(SiMe_3)_2]_3 (2) a truncated CF splitting pattern is derived from the spectra obtained. The parameters of an empirical Hamiltonian are fitted to the energies of 71 levels to give an r.m.s. deviation of 24.2 cm"-"1. The parameters obtained are compared with those of 2 and Nd[N(SiMe_3)_2]_3(CNC_6H_1_1)_2 (3). The observed trends of CF parameters are consistent with the results of simple model calculations in the framework of the angular overlap model. (orig.)

1998-07-24

181

Development of Bottom-up Representation of Industrial Energy Efficiency Technologies in Integrated Assessment Models for the Iron and Steel Sector |  

Wastenet

...3 MtC, with 78% of these emissions from integrated steel making (26.9 MtC) and the rest (22%)...6 MtC, with 71% of these emissions from integrated steel making (21.9 MtC) and the rest (29%)...1 million ton of carbon (MtC) in 1994 (3.9 MtC from integrated steel making, and 2.2 MtC from secondary ...7 MtC in 2002 (3.7 MtC from integrated steel making, and 2.0 MtC from secondary steel making), corresponding ...

182

Detection of intracardiac calcification using Fuji computed radiography  

International Nuclear Information System (INIS)

Fuji Computed Radiography (FCR) was evaluated for detection of intracardiac calcification as compared with conventional radiography in 77 patients. Intracardiac calcification was found in 37 patients (left coronary artery: 31, right coronary artery: 11, valve: 9) on cine-fluorography. The sensitivity for detecting these calcified foci with FCR was higher than conventional screen-film method. Especially, sensitivity for detecting left coronary artery calcification with FCR was significantly higher than conventional method (71 %, 32 %) (p < 0.01), Fine anatomical details of calcification were well shown on FCR. Chest radiography using FCR is of great use for detection of intracardiac calcification. (author).

1986-01-01

183

Artificial kidney engineering-Dialysis membrane and dialyzer for blood purification-  

Energy Technology Data Exchange (ETDEWEB)

Since artificial organs are intended to replicate chemical processes, knowledge of chemical engineering is essential in their design so that they will function with the maximum efficiency. The most commonly used artificial organ is the artificial kidney, a machine that performs a treatment known as hemodialysis. This process cleanses the bodies of renal failure patients by dialysis and filtration which are simple physiochemical processes. Hemodialysis membranes act to remove accumulated uremia toxins, excess ions and water from the patient via the dialysate, and to supply from the dialysate those ions that are insufficient. This paper describes dialysis membranes and dialyzers for blood purification, the solute transport mechanism of the membrane, and a technical evaluation of the dialysis membrane. Lastly, the next generation of artificial kidney is reviewed. 71 refs., 12 figs., 7 tabs.

1997-08-01

184

An application of artificial neural networks in breast cancer recognition using scintimammography  

International Nuclear Information System (INIS)

The aim of the study was to assess the usefulness of artificial neural networks (ANN) application in evaluation of scintimammography in the context of clinical data in the diagnosis of breast cancer. The results produced by ANN were compared with the diagnosis of two independent observers, nuclear medicine specialists. Material and methods: The clinical data and the numerical values derived from scintimammograms of 103 patients were the material for the study. The reference method was the result of histopathology study (core biopsy and /or FNB). Results: The overall sensitivity of physician diagnosis was 78% with specificity of 72%. The ANN produced 71% sensitivity and specificity of 73%. The physicians and ANN results were not significantly different (p=0.4619). Conclusions: Artificial neutral networks are useful tool in clinical diagnosis of breast cancer. (authors)

185

(#alpha#, t) reactions on "4"5Sc, "5"1V and "5"9Co nuclei at 27.2 MeV #alpha#-particle energy  

International Nuclear Information System (INIS)

Differential cross sections of the (#alpha#, t) reactions on "4"5Sc, "5"1V, and "5"9Co nuclei are measured in the 10-71 deg, 10-155 deg, and 10-171 deg angular ranges, respectively, with 27.2 MeV alpha particles. The cross sections have also been calculated on the basis of the distorted wave theory. The possibility of an unambiguous choice of the optical potential for alpha particles is discussed. The angular distribution calculations using several combinations of the optical potentials in the inlet and outlet channels of the reactions show that consistence between the calculations and the measurements is achieved (especially in angular range, less than 90 deg, if one of the potentials is chosen to be a sufficiently deep one.

186

Is uniform target dose possible in IMRT plans in the head and neck?  

International Nuclear Information System (INIS)

Purpose: Various published reports involving intensity-modulated radiotherapy (IMRT) plans developed using automated optimization (inverse planning) have demonstrated highly conformal plans. These reported conformal IMRT plans involve significant target dose inhomogeneity, including both overdosage and underdosage within the target volume. In this study, we demonstrate the development of optimized beamlet IMRT plans that satisfy rigorous dose homogeneity requirements for all target volumes (e.g., #+-#5%), while also sparing the parotids and other normal structures. Methods and Materials: The treatment plans of 15 patients with oropharyngeal cancer who were previously treated with forward-planned multisegmental IMRT were planned again using an automated optimization system developed in-house. The optimization system allows for variable sized beamlets computed using a three-dimensional convolution/superposition dose ...

2002-04-01

187

The Results of Curative Concurrent Chemoradiotherapy for Anal Carcinoma  

Energy Technology Data Exchange (ETDEWEB)

To evaluate the predictive factors for treatment response and prognostic factors affecting survival outcomes after concurrent chemoradiotherapy (CCRT) for patients with anal squamous cell carcinoma. Medical records of forty two patients with histologically confirmed analsquamous cell carcinoma, who had complete CCRT between 1993 and 2008, were reviewed retrospectively. Median age was 61.5 years (39-89 years), and median radiotherapy (RT) dose was 50.4 Gy (30.0-64.0 Gy). A total of 36 patients had equal to or less than T2 stage (85.7%). Fourteen patients (33.3%) showed regional nodal metastasis, 36 patients (85.7%) were treated with 5-fluorouracil (5-FU) plus mitomycin, and the remaining patients were treated by 5-FU plus cisplatinum. The median follow--up time was 62 months (2-202 months).The 5-year overall survival, locoregional relapse-free survival, disease-free survival, and colostomy-free survival rates were 86.0%, 71.7%, 71.7%, 78.2%, ...

2010-11-15

188

Hydrogen storage properties of the Mg-Ti-H system prepared by high-energy-high-pressure reactive milling  

Energy Technology Data Exchange (ETDEWEB)

Magnesium-based alloys are among the promising materials for hydrogen storage and fuel cell applications due to their high hydrogen content. In the present work, we investigated the hydrogen release/uptake properties of the Mg-Ti-H system. Samples were prepared from the mixtures of MgH{sub 2} and TiH{sub 2} in molar ratios of 7:1 and 4:1 using a high-energy-high-pressure (HEHP) mechanical ball-milling method under 13.8 MPa hydrogen pressure. Thermogravimetric analysis (TGA) showed that a relatively large amount of hydrogen (5.91 and 4.82 wt.%, respectively, for the above two samples) was released between 126 and 313 C while temperature was increased at a heating rate of 5 C min{sup -1} under an argon flow. The onset dehydrogenation temperature of these mixtures, which is 126 C, is much lower than that of MgH{sub 2} alone, which is 381 C. The activation energy of dehydrogenation was 71 kJ mol{sup -1}, which is much smaller than that of ...

2008-05-15

189

A comparison of tectonic and eustatic control on Maastrichtian depositional sequences, south-central Wyoming  

Energy Technology Data Exchange (ETDEWEB)

Timing and geometry of Maastrichtian third-order sequences and systems tracts of south-central Wyoming were mostly controlled by rapid basin subsidence resulting from thrust loading of foreland basin crust. The basement of the Red Desert/Washakie basin was affected by thrusting in the Sevier belt to the west and by thrusting along the edge of the Wind River Mountains and Granite Mountains. A transgressive systems tract consists of the youngest Ericson Formation above a regional unconformity, backstepping Almond Formation nearshore and nonmarine facies, and shelfal mudstones of the lower Lewis Shale. Regionally, the onset of transgression is younger from east to west, beginning at 71.5 Ma in eastern Wyoming and at 70.5-71 Ma in south-central Wyoming. The transgression culminated in a condensed shale section evident on gamma-ray logs that occurs throughout the basin. Above the gamma-ray zone, the highstand systems tract of the middle and upper ...

1990-05-01

190

Radioisotope production in the I.Ph.P.E. cyclotron for medical application  

International Nuclear Information System (INIS)

The production methods for seven radioisotopes, Ga-67, Sr-85, Pd-103, In-111, Tu-167, Hg-197 and Pb-203, by using a classical 1.5m cyclotron in the Institute of Physics and Power Engineering, Obninsk, USSR, are described. At present, more than 50 cyclotrons in different countries are used for the production of radioisotopes applied to medicine. Radioisotopes are produced with the cyclotron in the I.Ph.P.E. in the form of irradiated targets, which are delivered to Moscow radiopharmaceutical factory, where radiopharmaceuticals are produced on the base of these targets. The cyclotron is operated in two regimes providing the acceleration of protons, deuterons and alpha -particles. Two types of target assemblies are used for irradiation, the one is intended for the internal beam, and the other is for the external beam. The reactions used for the production of seven radioisotopes described above, the types of ...

191

Radioisotope production in the I. Ph. P. E. cyclotron for medical application  

Energy Technology Data Exchange (ETDEWEB)

The production methods for seven radioisotopes, Ga-67, Sr-85, Pd-103, In-111, Tm-167, Hg-197 and Pb-203, by using a classical 1.5m cyclotron in the Institute of Physics and Power Engineering, Obninsk, USSR, are described. At present, more than 50 cyclotrons in different countries are used for the production of radioisotopes applied to medicine. Radioisotopes are produced with the cyclotron in the I.Ph.P.E. in the form of irradiated targets, which are delivered to Moscow radiopharmaceutical factory, where radiopharmaceuticals are produced on the base of these targets. The cyclotron is operated in two regimes providing the acceleration of protons, deuterons and alpha -particles. Two types of target assemblies are used for irradiation, the one is intended for the internal beam, and the other is for the external beam. The reactions used for the production of seven radioisotopes described above, the types of ...

1982-01-01

192

Distortion-invariant color pattern recognition using multiple phase-shifted-reference-based joint transform correlation incorporating synthetic discriminant function  

Science.gov (United States)

This paper proposes a new pattern recognition system employing optical joint transform correlation (JTC) technique which offers a great number of advantages over similar digital techniques, including very fast operation, simple architecture and capability of updating the reference image in real time. The proposed JTC technique incorporates a synthetic discriminant function (SDF) of the target image estimated from different training images to make the pattern recognition performance invariant to noise and distortion. It then involves four different phase-shifted versions of the same target SDF reference image, which are individually joint transform correlated with the given input scene. When the correlation signals are combined, it produces a single cross-correlation peak corresponding to each potential target present in the given input scene. The proposed technique also includes a fringe-adjusted filter to generate a ...

2011-04-01

193

Uses of laser optical pumping to produce polarized ion beams  

Energy Technology Data Exchange (ETDEWEB)

Laser optical pumping can be used to produce polarized alkali atom beams or polarized alkali vapor targets. Polarized alkali atom beams can be converted into polarized alkali ion beams, and polarized alkali vapor targets can be used to produce polarized H/sup -/ or /sup 3/He/sup -/ ion beams. In this paper the authors discuss how the polarized alkali atom beams and polarized alkali vapor targets are used to produce polarized ion beams with emphasis on the production of polarized negative ion beams.

1983-04-01

194

The HARP experiment first physics results  

CERN Document Server

The HARP experiment at CERN is performing extensive measurements of hadron production cross sections and secondary particle yields, in the momentum range 1.5-15 GeV/c, over the full solid angle and using a large set of cryogenic and solid targets. First measurements of hadron production cross-sections in the forward region are reported using an aluminium target 5% of an interaction length thick and a proton beam of 12.9 GeV/c. A preliminary analysis in the large angle region of elastic scattering events produced with the cryogenic hydrogen target at 3 GeV/c beam momentum is also presented.

2005-01-01

195

Separation of carrier-free "1"7"6","1"7"7W and "1"7"6","1"7"7Ta produced in "1"6O irradiated holmium target  

International Nuclear Information System (INIS)

Carrier-free radionuclides of tungsten and tantalum, "1"7"6","1"7"7W and "1"7"6","1"7"7Ta have been produced by heavy ion activation of holmium target with 97 MeV "1"6O"5"+ beam. Radiochemical separation scheme has been developed to isolate tungsten and tantalum radionuclides from the holmium target matrix. (author)

2001-11-01

196

Separation of carrier free "1"7"6","1"7"7W and "1"7"6","1"7"7Ta radionuclides produced in "1"6O activated holmium metal target  

International Nuclear Information System (INIS)

Carrier-free radioisotopes of tungsten, "1"7"6","1"7"7W, and their corresponding daughter radionuclides "1"7"6","1"7"7Ta, have been produced in holmium target by heavy ion activation with "1"6O"5"+ beam. An attempt has been made to separate these carrier-free radionuclides from bulk holmium target through LLX using cation exchanger HDEHP. (author)

2001-02-07

197

Recovery of radioactive thallium isotopes from lead and bismuth targets irradiated by 1-GeV protons  

Energy Technology Data Exchange (ETDEWEB)

A simple highly efficient procedure has been developed for recovery of thallium radioisotopes from lead and bismuth targets irradiated by 1-GeV protons. The procedure is based on the use of extraction chromatography. The cross-sections have been determined for formation of {sup 200}Pb, {sup 201}Pb, {sup 202m}Pb, and {sup 203}Pb radioisotopes in targets from lead with natural isotopic composition, irradiated by 1-GeV protons.

1995-03-01

198

Recovery of radioactive thallium isotopes from lead and bismuth targets irradiated by 1-GeV protons  

International Nuclear Information System (INIS)

A simple highly efficient procedure has been developed for recovery of thallium radioisotopes from lead and bismuth targets irradiated by 1-GeV protons. The procedure is based on the use of extraction chromatography. The cross-sections have been determined for formation of "2"0"0Pb, "2"0"1Pb, "2"0"2"mPb, and "2"0"3Pb radioisotopes in targets from lead with natural isotopic composition, irradiated by 1-GeV protons.

199

Preliminary Study of Plasma Stream Interaction with Tungsten Target within RPI-IBIS Facility  

International Nuclear Information System (INIS)

The paper presents results of experimental research on the interaction of a pulsed plasma-ion stream with a tungsten (W) target. The pulsed hydrogen plasma was produced within the RPI-IBIS (Multi-Rod Plasma Injector) facility at IPJ in Swierk. Measurements were carried out by means of optical spectroscopy and corpuscular diagnostic techniques. For experiments with the W-target the operational conditions (so-called PID mode) were chosen when a clean hydrogen plasma stream was generated. Attention was paid to the identification of WI and WII spectral lines.

2006-01-01

200

Modified-VSIMM algorithm with an application to the naval fire control technology  

British Library Electronic Table of Contents (United Kingdom)

A modified variable structure interacting multiple model (M-VSIMM) estimator for complex hybrid maneuver target tracking is presented. The M-VSIMM could potentially be applied to fire control systems (FCS) used on warships. Target model groups were designed using 3D dimensional dynamic target models. Optimal model group selection logic was proposed, contrary to the activation and termination logic in the original VSIMM. The system will respond faster with optimal model group selection logic. After performing simulations, the tracking performances of the Kalman, ?-?(-?), VDIE, IMM and M-VSIMM filters were compared under various maneuvering conditions.

2011-01-01

201

Experiments to investigate the effects of radiative cooling on plasma jet collimation  

CERN Document Server

Preliminary experiments have been performed to investigate the effects of radiative cooling on plasma jets. Thin (3 um - 5 um) conical shells were irradiated with an intense laser, driving jets with velocities > 100 km/s. Through use of different target materials - aluminium, copper and gold - the degree of radiative losses was altered, and their importance for jet collimation investigated. A number of temporally resoved optical diagnostics was used, providing information about the jet evolution. Gold jets were seen to be narrower than those from copper targets, while aluminium targets produced the least collimated flows.

2010-01-01

202

Convoy electron production in polycrystalline and monocrystalline targets  

Energy Technology Data Exchange (ETDEWEB)

The velocity distribution of electrons ejected close to the forward direction by 0.8-2 MeV/A ions traversing various solid targets, including a Au monocrystal, is measured in coincidence with emerging charge-selected ions. The velocity spectrum is observed to be independent of outgoing projectile velocity and charge state for polycrystalline targets. Measurements on the Au crystal under channeling conditions show dependences on final charge state, and are tentatively explained by assuming that the main contribution to the production yield comes from the non-channeled fraction of the ions. A simple model for the creation of the forward-ejected electrons is proposed, which accounts for most of the experimental findings.

1980-01-01

203

Computer-assisted rotation and multiple stationary irradiation technique  

International Nuclear Information System (INIS)

A computer-assisted rotation and stationary conformation radiotherapy system with overrunning multileaf collimators has been developed. This system can produce any shape of target volume, including a number of target areas outside the axis of the rotation, regardless of the location of the axis at 360"0 rotation irradiation. In addition, by changing the dose rate and deleting a partial region within a field, multiple stationary irradiation can produce more homogeneous target volumes - thus avoiding excessive irradiation to critical organs - than the rotation technique. (orig.).

204

Centroid and Envelope Dynamics of High-intensity Charged Particle Beams in an External Focusing Lattice and Oscillating Wobbler  

Energy Technology Data Exchange (ETDEWEB)

The centroid and envelope dynamics of a high-intensity charged particle beam are investigated as a beam smoothing technique to achieve uniform illumination over a suitably chosen region of the target for applications to ion-beam-driven high energy density physics and heavy ion fusion. The motion of the beam centroid projected onto the target follows a smooth pattern to achieve the desired illumination, for improved stability properties during the beam-target interaction. The centroid dynamics is controlled by an oscillating "wobbler", a set of electrically-biased plates driven by RF voltage. __________________________________________________

2010-04-28

205

A final report for: Gallium arsenide P-I-N detectors for high-sensitivity imaging of thermal neutrons  

Energy Technology Data Exchange (ETDEWEB)

This SBIR Phase I developed neutron detectors made from gallium arsenide (GaAs) p-type/ intrinsic/n-type (P-I-N) diodes grown by metalorganic chemical vapor deposition (MOCVD) onto semi-insulating (S1) bulk GaAs wafers. A layer of isotonically enriched boron-10 evaporated onto the front surface serves to convert incoming neutrons into lithium ions and a 1.47 MeV alpha particle which creates electron-hole pairs that are detected by the GaAs diode. Various thicknesses of ''intrinsic'' (I) undoped GaAs were tested, as was use of a back-surface field (BSF) formed from a layer of Al{sub x}Ga{sub 1-x}As. Schottky-barrier diodes formed from the same structures without the p+ GaAs top layer were tested as a comparison. After mesa etching and application of contacts, devices were tested in visible light before application of the boron coating. Internal quantum efficiency (IQE) of the best diode near the GaAs bandedge is over 90%. The ...

1999-04-01

206

Yields of Residual Nuclei from Proton-Irradiated Materials  

International Science & Technology Center (ISTC)

Experimental and Theoretical Study of the Residual Nuclide Production in 40-2600 MeV Proton-Irradiated Thin Targets of ADS Basic Materials

207

Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates?  

UK PubMed Central (United Kingdom)

Understanding the physical characteristics of the local microenvironment in which Mycobacterium tuberculosis resides is an important goal that may allow the targeting of metabolic processes...Full Text Available

2008-06-01

209

The influence of target backing on ion-beam electron spectra  

International Nuclear Information System (INIS)

Several different aspects of the influence of the target backing on in-beam electron spectra following compound nuclear reactions induced by accelerated ions at tandem energies irradiating backed targets are discussed in detail. This discussion is illustrated by a few typical examples, such as "1"2C"5"+ and "3"1P"1"0"+ beams at 4 MeV/u bombarding Sn(+Be), Sn(+Au), Pb(+C) backed targets. Moreover, the relative influence of electron backscattering, electron Doppler shift and Doppler broadening as well as #delta#-electron emission on the low energy electron spectra (E_e#<=#100 keV) obtained under such conditions are investigated in the frame of the available experimental data. (orig.).

210

The importance of an accurate target wave function in variational calculations for (e^{+}-H_{2}) scattering  

CERN Document Server

Using the complex Kohn method, we have calculated variational values of phase shifts and the annihilation parameter, Z_{eff}, for the elastic scattering of positrons by molecular hydrogen. Our results are sensitive to small changes in the accuracy of the wave function representing the target hydrogen molecule. We have developed a systematic approach to demonstrate that, at low positron energies, there are particular forms of the Kohn trial wave function for which the results of variational calculations are not reliable, even when the target wave function accounts for as much as 96.8% of the correlation energy of H_{2}. We find that reliable results can be recovered if our calculations are extended to admit more sophisticated target wave functions accounting for 99.7% of the correlation energy. Remaining discrepancies between theory and experiment are briefly discussed.

2008-01-01

211

The Growth Cone Cytoskeleton in Axon Outgrowth and Guidance  

UK PubMed Central (United Kingdom)

Axon outgrowth and guidance to the proper target requires the coordination of filamentous (F)-actin and microtubules (MTs), the dynamic cytoskeletal polymers that promote shape change and locomotion....Full Text Available

212

The Development of New Methods for Solving the Target ...  

Science.gov (United States)

... and 7 survey papers. On the inverse Stefan problem he wrote 3 research papers and 1 survey paper. The papers on inverse ...

1984-07-18

213

Target space duality I: general theory  

Energy Technology Data Exchange (ETDEWEB)

We develop a systematic framework for studying target space duality at the classical level. We show that target space duality between manifolds M and M-tilde arises because of the existence of a very special symplectic manifold. This manifold locally looks like MxM-tilde and admits a double fibration. We analyze the local geometric requirements necessary for target space duality and prove that both manifolds must admit flat orthogonal connections. We show how abelian duality, nonabelian duality and Poisson-Lie duality are all special cases of a more general framework. As an example we exhibit new (nonlinear) dualities in the case M=M-tilde=R{sup n}.

2000-09-25

214

Studies of relativistic heavy ion collisions at the AGS (Experiment 814)  

Energy Technology Data Exchange (ETDEWEB)

This report discusses the experimental setup of experiment 814 at Brookhaven AGS. This experiment involves the collision of silicon ions with target nuclei. The detector systems are discussed primarily. (LSP)

1990-01-01

215

Smoking and reproduction: The oviduct as a target of cigarette smoke  

UK PubMed Central (United Kingdom)

The oviduct is an exquisitely designed organ that functions in picking-up ovulated oocytes, transporting gametes in opposite directions to the site of fertilization, providing a suitable environment...Full Text Available

216

Simultaneous recognition and segmentation of cells: application in C.elegans  

UK PubMed Central (United Kingdom)

Motivation: Automatic recognition of cell identities is critical for quantitative measurement, targeting and manipulation of cells of model animals at single-cell resolution. It has been...Full Text Available

2011-10-15

217

Principles of antibody therapy.  

UK PubMed Central (United Kingdom)

The success of monoclonal antibodies in clinical practice is dependent on good design. Finding a suitable target is the most important part as other properties of the antibody can be altered by genetic...Full Text Available

1992-12-05

218

Novel Cytotoxic Vectors Based on Adeno-Associated Virus  

Wastenet

positive primary PymT breast cancer cells in primary co-cultured tumor tissue, suggesting target specificity of

219

Measured Temperatures of Solid Rocket Motors Dump Stored ...  

Science.gov (United States)

... TARGET SENSOR-MK 80 SERIES BOMBS ... 5-inch-, and 2.75-inch- diameter rocket motors that ... balance when compared to incoming solar radiation ...

1989-07-01

220

Knowledge-Based Identification of the ERK2/STAT3 Signal Pathway as a Therapeutic Target for Type 2 Diabetes and Drug Discovery  

British Library Electronic Table of Contents (United Kingdom)

Many existing agents for diabetes therapy are unable to restore or maintain normal glucose homeostasis or prevent the eventual emergence of hyperglycemia-related complication. Therefore, agents based on novel mechanisms are sought to complement and extend the current therapeutic approaches. Based on the initial paper research, we focused on active STAT3 as an attractive pharmacological target for type 2 diabetes. The subsequent text mining with a unique query to identify suppressors but not activators of STAT3 revealed the ERK2/STAT3 pathway as a novel diabetes target. The description of ERK2 inhibitors as diabetes target had not been found in our text mining research at present. The mechanism-based peptide inhibitor for ERK2 was identified using the knowledge of the KIM sequence, which ha...

2011-01-01

221

Johnson News - NASA  

Science.gov (United States)

Nov 21, 2003... for the European Space Agency's Automated Transport Vehicle, a new, uncrewed station cargo vehicle targeted for launch late next year. ...

222

Ion channels, transporters, and pumps as targets for heart failure  

UK PubMed Central (United Kingdom)

Congestive heart failure (CHF) is a leading cause of morbidity and mortality. CHF is marked by atrial and ventricular enlargement and reduced cardiac contractility, as well as an association...Full Text Available

2009-10-01

223

Imaging immune response in vivo  

UK PubMed Central (United Kingdom)

PurposeClinical trials have commenced to evaluate the feasibility of targeting malignant gliomas with genetically engineered cytolytic T-cells (CTLs) delivered directly...Full Text Available

2008-06-15

224

Heat shock proteins as emerging therapeutic targets  

UK PubMed Central (United Kingdom)

Chaperones (stress proteins) are essential proteins to help the formation and maintenance of the proper conformation of other proteins and to promote cell survival after a large variety of environmental...Full Text Available

2005-11-01

225

Genomics of human longevity  

UK PubMed Central (United Kingdom)

In animal models, single-gene mutations in genes involved in insulin/IGF and target of rapamycin signalling pathways extend lifespan to a considerable extent. The genetic, genomic and epigenetic influences...Full Text Available

2011-01-12

226

Gene therapy for ocular diseases  

UK PubMed Central (United Kingdom)

The eye is an easily accessible, highly compartmentalised and immune-privileged organ that offers unique advantages as a gene therapy target. Significant advancements have been made in understanding...Full Text Available

2011-05-01

227

GAVA: Spectral Simulation for In Vivo MRS Applications  

UK PubMed Central (United Kingdom)

An application that provides a flexible and easy to use interface to the GAMMA spectral simulation package is described that is targeted at investigations using in vivo MR spectroscopic methods....Full Text Available

2007-04-01

228

Evaluation of phenylpiperazines as targeting agents for neuroblastoma.  

UK PubMed Central (United Kingdom)

The potential of radiolabelled phenylpiperazines as agents for the detection and therapy of tumours of neural crest origin was evaluated by in vitro pharmacological studies with human neuroblastoma...Full Text Available

1996-09-01

229

Effects of voicing in the recognition of concurrent syllables (L)a)  

UK PubMed Central (United Kingdom)

This letter reports a study designed to measure the benefits of voicing in the recognition of concurrent syllables. The target and distracter syllables were either voiced or whispered, producing...Full Text Available

2009-12-01

230

Dynamic clamp with StdpC software  

UK PubMed Central (United Kingdom)

Dynamic clamp is a powerful method that allows the introduction of artificial electrical components into target cells to simulate ionic conductances and synaptic inputs. This method is based...Full Text Available

2011-03-01

231

Dynamic Weapon-Target Assignment Problems with ...  

Science.gov (United States)

... defense's weapons are Space-based kinetic-kill vehicles ... I ti I obtained by dividing the weapons as ... of the optimal weapon-arge assigntments and ...

1988-06-01

232

Cooperative Charging Effects of Fibers From Electrospinning ...  

Science.gov (United States)

... In the Proceedings of INTC 2003, we studied charging effects on target coverage during electrospinning (16). ... of Fibers from Electrospinning of ...

2005-01-05

233

Comparative genomics of insect juvenile hormone biosynthesis?  

UK PubMed Central (United Kingdom)

The biosynthesis of insect juvenile hormone (JH) and its neuroendocrine control are attractive targets for chemical control of insect pests and vectors of disease. To facilitate the molecular...Full Text Available

2006-04-01

234

Cholinergic modulation of multivesicular release regulates striatal synaptic potency and integration  

UK PubMed Central (United Kingdom)

The pleiotropic actions of neuromodulators on pre- and postsynaptic targets present challenges to disentangling the mechanisms underlying regulation of synaptic transmission. Within the striatum,...Full Text Available

2009-09-01

235

Bacterial flora-typing with targeted, chip-based Pyrosequencing  

UK PubMed Central (United Kingdom)

BackgroundThe metagenomic analysis of microbial communities holds the potential to improve our understanding of the role of microbes in clinical conditions. Recent, dramatic improvements...Full Text Available

236

Approaches to the evaluation of chemical-induced immunotoxicity.  

UK PubMed Central (United Kingdom)

The immune system plays a crucial role in maintaining health; however, accumulating evidence indicates that this system can be the target for immunotoxic effects caused by a variety of chemicals including...Full Text Available

1995-12-01

237

An Extended Kalman Filter for Use in a Shared Aperture ...  

Science.gov (United States)

... used to track a point source target ... A one sigma tracking error of .2 ... LOOKING INFRARED SYSTEMS, *KALMAN FILTERING, SIGNAL PROCESSING ...

1978-12-01

238

A comprehensive assessment of N-terminal signal peptides prediction methods  

UK PubMed Central (United Kingdom)

BackgroundAmino-terminal signal peptides (SPs) are short regions that guide the targeting of secretory proteins to the correct subcellular compartments in the cell. They are cleaved...Full Text Available

239

Schottky barrier and homojunction gallium arsenide solar cells  

Energy Technology Data Exchange (ETDEWEB)

New techniques were developed to construct Schottky barrier and homojunction solar cells on GaAs substrates. Schottky barrier metal-semiconductor solar cells were produced for the first time on p-type GaAs substrate using a sputter-deposition method to form the barrier. The sputter deposition of gold or gold/palladium is the key to the method since normal thermal evaporation of gold onto p-type GaAs produces ohmic contacts. The results of this investigation are consistent with the idea that sputter damage produces donor type surface states on GaAs. Barrier heights were measured for both p-type sputtered and n-type thermally evaporated diodes using current-voltage and capacitance-voltage methods. Deep-level transient spectroscopy was used to identify the trap center concentration and energy levels for both diodes in an effort to explain the relatively large dark current in the p-type sputtered diodes. Homojunction GaAs solar cells were fabricated using several techniques. One involved ...

1983-01-01

240

PVT -- A photovoltaic/thermal concentrator total energy system: Final phase 1 project report. Building opportunities in the U.S. for photovoltaics (PV:BONUS) Two  

Energy Technology Data Exchange (ETDEWEB)

United Solar completed its Phase 1 report and its proposal for Phase 2 of the PVBONUS Two program at the end of March 1998. At the same time, it also completed and submitted a proposal to the California Energy Commission PIER program for additional funding to cost-share development and testing of a pre-production model of the PVT-14. It was unsuccessful in both of these proposed efforts. While waiting for the proposal decisions, work continued in April and May to analyze the system design and component decisions described below. This document is a final summation report on the Phase 1 effort of the PVBONUS Two program that describes the key technical issues that United Solar and its subcontractor, Industrial Solar Technology Corporation, worked on in preparation of a Phase 2 award. The decisions described were ones that will guide the design and fabrication of a pre-production prototype of a 1500:1 mirrored concentrator with gallium arsenide cells when United solar ...

1998-12-31

241

Fundamentals of focused ion beam nanostructural processing: below,at and above the surface  

Energy Technology Data Exchange (ETDEWEB)

This article considers the fundamentals of what happens in asolid when it is impacted with a medium energy gallium ion. The study ofthe ion/sample interaction at the nanometer scale is applicable to mostfocused ion beam (FIB) based work even if the FIB/sample interaction isonly a step in the process, e.g., micromachining or microelectronicdevice processing. Whereas the objective in other articles in this issueis to use the FIB tool to characterize a material or to machine a deviceor transmission electron microscopy (TEM) sample, the goal of the FIB inthis article is to have the FIB/sample interaction itself become theproduct. To that end, the FIB/sample interaction is considered in threecategories according to geometry: below, at, and above the surface.First, the FIB ions can penetrate the top atom layer(s) and interactbelow the surface. Ion implantation and ion damage on flat surfaces havebeen comprehensively examined; however, FIB applications require thefurther ...

2007-03-30

242

Focused ion beam assisted three-dimensional rock imaging at submicron scale  

Energy Technology Data Exchange (ETDEWEB)

Computation of effective flow properties of fluids in porous media based on three dimensional (3D) pore structure information has become more successful in the last few years, due to both improvements in the input data and the network models. Computed X-ray microtomography has been successful in 3D pore imaging at micron scale, which is adequate for many sandstones. For other rocks of economic interest, such as chalk and diatomite, submicron resolution is needed in order to resolve the 3D-pore structure. To achieve submicron resolution, a new method of sample serial sectioning and imaging using Focused Ion Beam (FIB) technology has been developed and 3D pore images of the pore system for diatomite and chalk have been obtained. FIB was used in the milling of layers as wide as 50 micrometers and as thin as 100 nanometers by sputtering of atoms from the sample surface. The focused ion beam, consisting of gallium ions (Ga+) accelerated by potentials of up to 30 kV and ...

2003-05-09

243

Advanced radiation detector development: Advanced semiconductor detector development: Development of a oom-temperature, gamma ray detector using gallium arsenide to develop an electrode detector  

Energy Technology Data Exchange (ETDEWEB)

The advanced detector development project at the University of Michigan has completed the first full year of its current funding. Our general goals are the development of radiation detectors and spectrometers that are capable of portable room temperature operation. Over the past 12 months, we have worked primarily in the development of semiconductor spectrometers with {open_quotes}single carrier{close_quotes} response that offer the promise of room temperature operation and good energy resolution in gamma ray spectroscopy. We have also begun a small scale effort at investigating the properties of a small non-spectroscopic detector system with directional characteristics that will allow identification of the approximate direction in which gamma rays are incident. These activities have made use of the extensive clean room facilities at the University of Michigan for semiconductor device fabrication, and also the radiation measurement capabilities provided in our laboratory in the Phoenix ...

1995-11-01

244

Testing of CFC Targets by Plasma Heat Fluxes Relevant to Elms and Mitigated Disruptions in ITER  

International Nuclear Information System (INIS)

Carbon fibre composite (CFC) was irradiated by hot plasma streams at plasma gun facility MK-200UG. The CFC targets were tested by plasma loads relevant to Edge Localized Modes (ELM) and mitigated disruptions in ITER. Onset condition of CFC evaporation and properties of evaporated carbon were studied by use of infrared pyrometry and visible spectroscopy.

2006-01-01

245

Targeted suppression of Has2 mRNA in mouse cumulus cell-oocyte complexes by adenovirus-mediated short-hairpin RNA expression  

UK PubMed Central (United Kingdom)

RNA interference (RNAi) is an effective tool for studying gene function in oocytes, but no studies have targeted somatic cells of primary cultured cumulus cell-oocyte complexes (COCs). This...Full Text Available

2009-06-01

246

Targeted Capture and Next-Generation Sequencing Identifies C9orf75, Encoding Taperin, as the Mutated Gene in Nonsyndromic Deafness DFNB79  

UK PubMed Central (United Kingdom)

Targeted genome capture combined with next-generation sequencing was used to analyze 2.9 Mb of the DFNB79 interval on chromosome 9q34.3, which includes 108 candidate genes. Genomic...Full Text Available

2010-03-12

247

Structure functions at low Q^2: higher twists and target mass effects  

Energy Technology Data Exchange (ETDEWEB)

We review the physics of structure functions at low Q{sup 2}, focusing on the phenomenon of quark-hadron duality and the resonance-scaling transition, both phenomenologically and in the context of quark models. We also present a new implementation of target mass corrections to nucleon structure functions which, unlike existing treatments, has the correct kinematic threshold behavior at finite Q{sup 2} in the x -> 1 limit.

2006-05-22

248

Production of "2"0"3Pb by proton irradiation of Bi  

International Nuclear Information System (INIS)

Production of lead-203 by proton irradiation of bismuth metal has been investigated as a replacement method for commercially available lead-203. Targets of bismuth metal (0.1 cm thick) were irradiated for periods of 1-3 hours with 90 MeV protons. After processing of the target, the estimated yield of lead-2-3 was 30 millicuries/microamp.

1990-06-24

249

PV Conversion Technologies, Session: OPV, Sensitized, Seed (Presentation)  

Energy Technology Data Exchange (ETDEWEB)

The NREL Sensitized Solar Cell (SSC) Core Program supports the Solar America Initiative by: (1) targeting new devices and processes for commercialization by 2015 that are less expensive, more efficient, highly reliable, and environmentally benign; (2) collaborating with DOE OS/BES to conduct basic research targeting breakthroughs in key areas, such as ultra-high efficiency and/or ultra-low cost materials and devices.

2008-04-01

250

Modeled Neutron Induced Nuclear Reaction Cross Sections for Radiochemistry in the region of Iridium and Gold  

International Nuclear Information System (INIS)

We have developed a set of modeled nuclear reaction cross sections for use in radiochemical diagnostics. Systematics for the input parameters required by the Hauser-Feshbach statistical model were developed and used to calculate neutron induced nuclear reaction cross sections for targets ranging from osmium (Z = 76) to gold (Z = 79). Of particular interest are the cross sections on Ir and Au including reactions on isomeric targets.

2008-02-01

251

Kidney-specific allo- and autoantibodies in the alloantibody response to rat kidney: the use of kidney homogenate as a target for serological analysis.  

UK PubMed Central (United Kingdom)

LEW anti-DA kidney and DA anti-LEW kidney sera were assayed using an indirect 125I anti-immunoglobulin-binding assay with kidney homogenate as target. This allowed the full spectrum of antibodies to...Full Text Available

1980-04-01

252

In vitro atrazine-exposure inhibits human natural killer cell lytic granule release  

International Nuclear Information System (INIS)

The herbicide atrazine is a known immunotoxicant and an inhibitor of human natural killer (NK) cell lytic function. The precise changes in NK cell lytic function following atrazine exposure have not been fully elucidated. The current study identifies the point at which atrazine exerts its affect on the stepwise process of human NK cell-mediated lyses of the K562 target cell line. Using intracellular staining of human peripheral blood lymphocytes, it was determined that a 24-h in vitro exposure to atrazine did not decrease the level of NK cell lytic proteins granzyme A, granzyme B or perforin. Thus, it was hypothesized that atrazine exposure was inhibiting the ability of the NK cells to bind to the target cell and subsequently inhibit the release of lytic protein from the NK cell. To test this hypothesis, flow cytometry and fluorescent microscopy were employed to analyze NK cell-target cell co-cultures following atrazine ...

2007-06-01

253

Highly efficient gene silencing using perfect complementary artificial miRNA targeting AP1 or heteromeric artificial miRNA targeting AP1 and CAL genes  

UK PubMed Central (United Kingdom)

Gene silencing is a useful technique for elucidating biological function of genes by knocking down their expression. A recently developed artificial microRNAs (amiRNAs) exploits an endogenous...Full Text Available

2009-03-01

254

Electron accelerator unit for electron beam therapy  

Energy Technology Data Exchange (ETDEWEB)

An electron accelerator unit is described for electron beam therapy, comprising: a source of an electron beam; means for finally directing at least a portion of the beam to a therapy site, the directing means being mechanically independent of, and electrically isolated from, the source, and having a target area; and means for aligning the source with the directing means, the aligning means comprising means for projecting at least one beam of light from the source toward the target area.

1987-01-27

255

Electron accelerator unit for electron beam therapy  

International Nuclear Information System (INIS)

An electron accelerator unit is described for electron beam therapy, comprising: a source of an electron beam; means for finally directing at least a portion of the beam to a therapy site, the directing means being mechanically independent of, and electrically isolated from, the source, and having a target area; and means for aligning the source with the directing means, the aligning means comprising means for projecting at least one beam of light from the source toward the target area.

256

Double-electron-capture cross section for I/sup +/ in a magnesium-vapor target  

Energy Technology Data Exchange (ETDEWEB)

Measurements of the double-electron-capture process in which a positive ion of iodine becomes a negative ion in a single collision with a magnesium atom are reported between 20 and 90 keV. The cross section is comparable to that for the rare gases and not as large as might be expected from a two-valence-electron atom. This process is probably insignificant in the production of negative ion beams using a magnesium-vapor target.

1987-06-15

257

Development of High-Efficiency Low-Lift Vapor Compression System - Final Report  

Energy Technology Data Exchange (ETDEWEB)

PNNL, with cofunding from the Bonneville Power Administration (BPA) and Building Technologies Program, conducted a research and development activity targeted at addressing the energy efficiency goals targeted in the BPA roadmap. PNNL investigated an integrated heating, ventilation and air conditioning (HVAC) system option referred to as the low-lift cooling system that potentially offers an increase in HVAC energy performance relative to ASHRAE Standard 90.1-2004.

2010-03-31

258

Designing Human m1 Muscarinic Receptor-Targeted Hydrophobic Eigenmode Matched Peptides as Functional Modulators  

UK PubMed Central (United Kingdom)

A new proprietary de novo peptide design technique generated ten 15-residue peptides targeting and containing the leading nontransmembrane hydrophobic autocorrelation wavelengths, “modes”,...Full Text Available

2004-03-01

259

Achieving cholesterol targets by individualizing starting doses of statin according to baseline low-density lipoprotein cholesterol and coronary artery disease risk category: The CANadians Achieve Cholesterol Targets Fast with Atorvastatin Stratified Titration (CanACTFAST) study  

UK PubMed Central (United Kingdom)

BACKGROUND:Despite an increasing body of evidence on the benefit of lowering elevated levels of low-density lipoprotein cholesterol (LDL-C), there is still considerable concern that...Full Text Available

2010-02-01

260

A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions  

UK PubMed Central (United Kingdom)

MicroRNAs are short (∼22 nucleotides) noncoding RNAs that regulate the stability and translation of mRNA targets. A number of computational algorithms have been developed to help predict which...Full Text Available

2008-11-01

261

Radiation inactivation target size of rat adipocyte glucose transporters in the plasma membrane and intracellular pools  

Energy Technology Data Exchange (ETDEWEB)

The in situ assembly states of the glucose transport carrier protein in the plasma membrane and in the intracellular (microsomal) storage pool of rat adipocytes were assessed by studying radiation-induced inactivation of the D-glucose-sensitive cytochalasin B binding activities. High energy radiation inactivated the glucose-sensitive cytochalasin B binding of each of these membrane preparations by reducing the total number of the binding sites without affecting the dissociation constant. The reduction in total number of binding sites was analyzed as a function of radiation dose based on target theory, from which a radiation-sensitive mass (target size) was calculated. When the plasma membranes of insulin-treated adipocytes were used, a target size of approximately 58,000 daltons was obtained. For adipocyte microsomal membranes, we obtained target sizes of approximately 112,000 and 109,000 daltons prior ...

1987-06-15

262

Proton G{sub E}/G{sub M} from beam-target asymmetry  

Science.gov (United States)

The ratio of the proton's electric to magnetic form factor, G{sub E}/G{sub M}, can be extracted in elastic electron-proton scattering by measuring cross sections, beam-target asymmetry, or recoil polarization. Separate determinations of G{sub E}/G{sub M} by cross sections and recoil polarization observables disagree for Q{sup 2}>1 (GeV/c){sup 2}. Measurement by a third technique might uncover an unknown systematic error in either of the previous measurements. The beam-target asymmetry has been measured for elastic electron-proton scattering at Q{sup 2} = 1.51 (GeV/c){sup 2} for target spin orientation aligned perpendicular to the beam momentum direction. This is the largest Q{sup 2} at which G{sub E}/G{sub M} has been determined by a beam-target asymmetry experiment. The result, {mu}G{sub E}/G{sub M}=0.884{+-}0.027{+-}0.029, is compared to previous world data.

2006-09-15

263

One-class classifiers and their application to synthetic aperture radar target recognition  

Energy Technology Data Exchange (ETDEWEB)

Target recognition requires the ability to distinguish targets from non-targets, a capability called one-class generalization. To function as a one-class classifier, a neural network must have three types of generalization: within-class, between-class, and out-of-class. We discuss these three types of generalization and identify neural network architectures that meet these requirements. We have applied our one-class classifier ideas to the problem of automatic target recognition in synthetic aperture radar. We have compared three neural network algorithms: Carpenter and Grossberg`s algorithmic version of the Adaptive Resonance Theory (ART-2A), Kohonen`s Learning Vector Quantization (LVQ), and Reilly and Cooper`s Restricted Columb Energy network (RCE). The ART 2-A neural network has given the best results, with 100% within-class, and out-of-class generalization. Experiments show that the network`s ...

1992-10-01

264

One-class classifier networks for target recognition applications  

Energy Technology Data Exchange (ETDEWEB)

Target recognition requires the ability to distinguish targets from non-targets, a capability called one-class generalization. Many neural network pattern classifiers fail as one-class classifiers because they use open decision boundaries. To function as one-class classifier, a neural network must have three types of generalization: within-class, between-class, and out-of-class. We discuss these three types of generalization and identify neural network architectures that meet these requirements. We have applied our one-class classifier ideas to the problem of automatic target recognition in synthetic aperture radar. We have compared three neural network algorithms: Carpenter and Grossberg`s algorithmic version of the Adaptive Resonance Theory (ART-2A), Kohonen`s Learning Vector Quantization (LVQ), and Reilly and Cooper`s Restricted Coulomb Energy network (RCE). The ART 2-A neural network gives the best ...

1993-01-01

265

Integral cross sections of 50.5 MeV #alpha# particle inelastic scattering on 1p and (2s-1d) shell nuclei and scattering mechanisms  

International Nuclear Information System (INIS)

Obtained experimental data on integral cross sections (ICS) of inelastic scattering of 50.5 MeV #alpha# particles with the excitation of "6","7Li, "9Be, "1"2","1"3C, "1"4C, "1"4N, "2"0Ne, "2"4Mg, "2"8Si nucleus low-lying energy levels are discussed. Regularities, detected in the behaviour of ICS forward scattering for 20-90 deg angles and backscattering for 90-160 deg angles for the target-nucleus under investigation are considered. Effect of reaction open channel number on #alpha#-particle scattering ICS where n,p,d- and #alpha#-channels were considered as the main channels for all the target-nuclei, is discussed. Dependence of #alpha#-particle scattering ICS on the target-nucleus level excitation energy and dependences of reaction open channel number on the channel spin, calculated for 50.5 MeV #alpha# particles and different target nuclei are shown in the diagrams. It is noted that the observed ...

266

Donut-shaped high-dose configuration for proton beam radiation therapy  

Energy Technology Data Exchange (ETDEWEB)

Background: the authors report on the conception and first clinical application of a donut-shaped high-dose configuration for proton therapy (PT). This approach allows one to intensify target volume dose coverage for targets encompassing a critical, dose-limiting structure - like here, the cauda equina -, whilst delivering minimal dose to other healthy structures surrounding the target, thereby reducing the integral dose. Methods and results: intensity-modulated PT methods (IMPT) for spot scanning were applied to create and deliver a donut-shaped high-dose configuration with protons, allowing treating > 75% of the target with at least 95% of the prescribed dose of 72.8 CGE, whilst restricting dose to the cauda equina to 60-65 CGE. Integral dose was lower by a factor of 3.3 as compared to intensity-modulated radiotherapy with photons (IMXT). Conclusion: IMPT and spot scanning technology allow a ...

2005-01-01

267

Donut-shaped high-dose configuration for proton beam radiation therapy  

International Nuclear Information System (INIS)

Background: the authors report on the conception and first clinical application of a donut-shaped high-dose configuration for proton therapy (PT). This approach allows one to intensify target volume dose coverage for targets encompassing a critical, dose-limiting structure - like here, the cauda equina -, whilst delivering minimal dose to other healthy structures surrounding the target, thereby reducing the integral dose. Methods and results: intensity-modulated PT methods (IMPT) for spot scanning were applied to create and deliver a donut-shaped high-dose configuration with protons, allowing treating > 75% of the target with at least 95% of the prescribed dose of 72.8 CGE, whilst restricting dose to the cauda equina to 60-65 CGE. Integral dose was lower by a factor of 3.3 as compared to intensity-modulated radiotherapy with photons (IMXT). Conclusion: IMPT and spot scanning technology allow a ...

2005-01-01

268

[Urinary infection in geriatric short stay: value of urinary strips].  

Science.gov (United States)

The blinded study of CBUE (cytobacteriological urine examination) test strips was carried out in 100 patients (65 women, 35 men), mean age 85.52 +/- 6.28 years, admitted for a short stay in a geriatrics department. Urinary infection was present in 19% of the cases. Typical clinical signs (pollakiuria, dysuria, hematuria, burning upon voiding) were rare, less than 10%. General signs, such as deterioration of general status (65% of the cases) and loss of autonomy (53% of the cases), on the other hand, were predominant and their relatively unspecific nature required a reliable screening test for urinary infection. Good results of sensitivity (89.5%), specificity (98.7%), and the leukocytes/nitrites values, confirmed the validity of the urine test strip in hospitalized elderly patients. In addition, the negative predictive value of the combination leukocytes and nitrites (90.8%) would have prevented 71 samples from being sent to the laboratory for CBUE, resulting in an ...

1997-01-01

269

[Legionella pneumonia caused by aspiration of hot spring water after sarin exposure].  

Science.gov (United States)

A 72-year-old man was exposed to the sarin gas attack in a Tokyo subway on March 20 th, 1995. After exposure, he noticed eye discomfort, chest tightness, headache and weakness of the lower limbs and oropharyngeal muscles. Despite these symptoms, he visited a hot spring on the same day with his family. On March 25 th, his muscle weakness progressed, and a low grade fever appeared. His muscle weakness disappeared 8 days after exposure to sarin, but respiratory failure rapidly developed, necessitating artificial ventilation within four day after hospitalization on March 28th. Chemotherapy with erythromycin, imipenem/cilastatin, and steroid pulse therapy was begu. PCR and culture of sputum collected by bronchofiberscopy were positive for Legionella pneumophila, serogroup I. His respiratory state improved, but subsequent infection with Pseudomonous aeruginosa. Enterobacter cloacae, and Candida tropicalis/glabrata caused his death 71 days after admission. Oropharyngeal ...

1998-03-01

270

Thin-Section CT findings of lung small peripheral adenocarcinoma detected by CT physical examination  

Energy Technology Data Exchange (ETDEWEB)

Subjects were 18 cases with adenocarcinoma of 20 mm or less in diameter, which were detected and resected surgically from September, 1993 to August, 1998. On these cases, thin-Section CT (TSCT) images were compared with pathological findings. Patients were 15 men and 3 women, with mean age of 63.4-year-old. An average tumor size was 11.5 mm (5-17 mm). According to pathological classification of Noguchi, type A as in 6 cases, type B in 3, type C in 7 and type F in 2. TSCT was carried by vas voltage =150 kVp, vas current =200 mA, beam width =2 mm, WW =2000 HU, and WL =-700 HU. The ratio of CT attenuation value in cancer by TSCT correlated with the ratio of aeration rate in the pathologic specimen. The cases of 30% or less on the ratio of CT attenuation value were 100% in types A and B, and 71% in type C. These results suggested that it is necessary to devide into two type in group of type C and the ratio of CT attenuation value is important on diagnosis of prognosis ...

1999-11-01

271

The uterine blush. A potential false-positive in Meckel's scan interpretation  

Energy Technology Data Exchange (ETDEWEB)

To determine the presence, prevalence, and clinical importance of /sup 99m/Tc pertechnetate uterine uptake, this retrospective analysis of 71 Meckel's scans was undertaken. Specifically, each study was evaluated for the presence of a focal accumulation of radiotracer cephalad to the bladder. Patients received an intravenous dose of 150 microCi/kg of /sup 99m/Tc pertechnetate. Each study consisted of 15 one minute anterior serial gamma camera images, and a 15, 30, and 60 minute anterior, right lateral and posterior scintiscan. Menstrual histories were obtained from all patients except two. No males (33/33), nor premenstrual (13/13), menopausal (4/4) or posthysterectomy (2/2) patients revealed a uterine blush. Eleven of 15 patients (73%) with regular menses demonstrated a uterine blush. They were in the menstrual or secretory phases of their cycle. Four demonstrated no uterine uptake, had regular periods, but were in the proliferative phase of their cycle. ...

1982-10-01

272

The origin of natural gas and the hydrocarbon charging history of the Yulin gas field in the Ordos Basin, China  

British Library Electronic Table of Contents (United Kingdom)

The genetic type, source and charging history of natural gas in the Yulin gas field in the Ordos Basin have been studied by combining the carbon isotopic composition of natural gas and geochemical characteristics of light hydrocarbons with carbon isotope fractionation model results and fluid inclusion analysis. The carbon isotopic composition of methane and ethane in the Yulin gas field is relatively enriched in ^1^3C with d^1^3C1 values ranging from -35.3%% to -29.8%% (average value=-32.4%%) and d^1^3C2 ranging from -26.3%% to -23.5%% (average value=-24.8%%). The C7 light hydrocarbons are predominated by methylcyclohexane, accounting for 65.8% to 80.9% (average value=71.6%), which is characteristic of coal-derived gas. Furthermore, the gas geochemistry indicates that, although marine lime...

2010-01-01

273

The epidemiology of gallstone disease in Rome, Italy. Part I. Prevalence data in men. The Rome Group for Epidemiology and Prevention of Cholelithiasis (GREPCO).  

Science.gov (United States)

A population of male civil servants in Rome, Italy, was investigated to determine the prevalence of symptomatic and asymptomatic gallstone disease. Field activities started in December, 1982 and were concluded in July, 1984. Diagnosis was made using real-time ultrasonography. Participation in the study was 71.5%. Prevalence of gallstone disease was 8.2% and increased with age from 2.3% in the 20- to 25-year-old age group to 14.4% in the 60- to 69-year-old age group, based on both presence of gallstones and history of cholecystectomy. About one-third of the subjects with gallstone disease had previously been submitted to cholecystectomy. Only 7.7% of the subjects with presence of gallstones complained of at least one episode of biliary pain in the preceding 5 years. Frequency of "minor" dyspeptic symptoms was not different between men with and those without gallstones. PMID:3391519

274

Synthesis of novel high-voltage cathode material LiCoPO{sub 4} via rheological phase method  

Energy Technology Data Exchange (ETDEWEB)

For the first time, rheological phase method, a simple and effective route, is applied to synthesize novel cathode material LiCoPO{sub 4}. X-ray diffraction spectrometer (XRD), X-ray photoelectron spectrometer (XPS), transmission electron microscope (TEM) and electrochemical impedance spectroscopy (EIS) are taken to investigate this material, respectively. XRD figure shows that the rheological sample is better crystallized than the solid-state one. XPS result of the rheological sample exhibits that the valence of Co is 2+. TEM images show that better dispersed particles with smaller size can be formed by rheological method comparing to the solid-state route. Charge-discharge test is carried out in the range of 3.0-5.0 V at 0.2 mA cm{sup -2}. The initial discharge capacity for rheological phase and solid-state powder is 71.5 and 30.9 mAh g{sup -1}, respectively. The better electrochemical property should be ascribed to the better crystallized rheological phase ...

2010-07-23

275

Synthesis of novel high-voltage cathode material LiCoPO4 via rheological phase method  

International Nuclear Information System (INIS)

For the first time, rheological phase method, a simple and effective route, is applied to synthesize novel cathode material LiCoPO4. X-ray diffraction spectrometer (XRD), X-ray photoelectron spectrometer (XPS), transmission electron microscope (TEM) and electrochemical impedance spectroscopy (EIS) are taken to investigate this material, respectively. XRD figure shows that the rheological sample is better crystallized than the solid-state one. XPS result of the rheological sample exhibits that the valence of Co is 2+. TEM images show that better dispersed particles with smaller size can be formed by rheological method comparing to the solid-state route. Charge-discharge test is carried out in the range of 3.0-5.0 V at 0.2 mA cm-2. The initial discharge capacity for rheological phase and solid-state powder is 71.5 and 30.9 mAh g-1, respectively. The better electrochemical property should be ascribed to the better crystallized rheological phase production with better ...

2010-07-23

276

Stable isotopes of authigenic minerals in variably-saturated fractured tuff  

Energy Technology Data Exchange (ETDEWEB)

Identifying stable isotope variation and mineralogical changes in fractured rock may help establish the history of climatic and geomorphological processes that might affect the isolation properties of a waste repository site. This study examines the use of the stable isotope ratios of oxygen ({sup 18}O/{sup 16}O) and carbon ({sup 13}C/{sup 12}C) in authigenic minerals as hydrogeochemical tools tracing low-temperature rock-water interaction in variably-saturated fractured stuff. Isotopic compositions of fracture-filling and rock matrix minerals in the Apache Leap tuff, near Superior, Arizona were concordant with geothermal temperatures and in equilibrium with water isotopically similar to present-day meteoric water and groundwater. Oxygen and carbon isotope ratios of fracture-filling, in unsaturated fractured tuff, displayed an isotopic gradient believed to result from near-surface isotopic enrichment due to evaporation rather than the effects of rock-water interaction. Oxygen isotope ...

1988-11-01

277

Spin-lattice relaxation in A-15 type intermetallic compounds  

Energy Technology Data Exchange (ETDEWEB)

The temperature dependence of T/sub 1/ spin-lattice relaxation time on /sup 51/V, /sup 69/Ga, /sup 71/Ga and Knight shift on /sup 51/V and /sup 29/Si nuclei in polycrystalline V/sub 3/Si, V/sub 3/Ga, V/sub 3/Ge and in the monocrystal V/sub 3/Si in normal state is investigated. For V/sub 3/Si and V/sub 3/Ga a rapid growth (T/sub 1/T)/sup -1/ is observed with temperature decrease while for V/sub 3/Ge the maximum (T/sub 1/T)/sup -1/ at T approximately equal to 60 K has been found. The temperature dependence peculiarities have been discussed on the basis of theoretical models available and zone structure calculations for A-15 compounds. The T/sub 1/ anisotropy and possibility of its experimental discovery are considered. Anisotropic contribution in (T/sub 1/T)/sup -1/ and contributions of d states of different symmetries into the electron state density at the Fermi level are estimated for V/sub 3/Si from T/sub 1/ measurements.

1981-04-01

278

Spin-lattice relaxation in A-15 type intermetallic compounds  

International Nuclear Information System (INIS)

The temperature dependence of T_1 spin-lattice relaxation time on "5"1V, "6"9Ga, "7"1Ga and Knight shift on "5"1V and "2"9Si nuclei in polycrystalline V_3Si, V_3Ga, V_3Ge and in the monocrystal V_3Si in normal state is investigated. For V_3Si and V_3Ga a rapid growth (T_1T)"-"1 is observed with temperature decrease while for V_3Ge the maximum (T_1T)"-"1 at T approximately equal to 60 K has been found. The temperature dependence peculiarities have been discussed on the basis of theoretical models available and zone structure calculations for A-15 compounds. The T_1 anisotropy and possibility of its experimental discovery are considered. Anisotropic contribution in (T_1T)"-"1 and contributions of d states of different symmetries into the electron state density at the Fermi level are estimated for V_3Si from T_1 measurements.

279

Self-consistent relativistic density-functional theory: Application to neutral uranium atom and some ions of lithium isoelectronic sequence  

Science.gov (United States)

In a relativistic density-functional theory the importance of the transverse photon contribution to the exchange potential in the high-density regime is pointed out. A neutral atom /sup 92/U is studied and its orbital energies calculated in the present scheme are compared with previous calculations based on relativistic Hartree, Dirac-Slater, and Dirac-Fock schemes and with experimental values from (electron spectroscopy for chemical analysis) ESCA studies. The present scheme is also used to calculate the orbital and total energies of some highly stripped ions of the Li isoelectronic sequence which occur as impurities in controlled thermonuclear plasma. These energies are found to be in close agreement with more involved Dirac-Fock results. Also, the relativistic effects significantly increase in going from C/sup 3 +/ to W/sup 71 +/ because the electronic density reaches values for which relativistic effects become large.

1980-07-01

280

Response of a Spent Fuel Transportation Cask to a Tunnel Fire Event  

Energy Technology Data Exchange (ETDEWEB)

The staff of the Spent Fuel Project Office at the U.S. Nuclear Regulatory Commission undertook the investigation and thermal analysis of the Baltimore tunnel fire event. This event occurred in the Howard Street tunnel, in Baltimore, Maryland, on July 18, 2001. The staff was tasked with assessing the consequences of this event on the transportation of spent nuclear fuel. This paper describes the staff's coordination with the following government and laboratory organizations: the National Transportation Safety Board (NTSB), to determine the details of the train derailment and fire; the National Institute of Standards and Technology (NIST), to quantify the thermal conditions within the tunnel; the Center for Nuclear Waste Regulatory Analysis (CNWRA), to validate the NIST evaluations, and the Pacific Northwest National Laboratory (PNNL), to assist in the thermal analysis. The results of the staff's review and analysis efforts are also discussed. The staff has concluded ...

2003-02-25

281

Removal of phosphate by mesoporous ZrO{sub 2}  

Energy Technology Data Exchange (ETDEWEB)

A type of mesoporous ZrO{sub 2} was synthesized and its phosphate removal potential was investigated in this study. The adsorption isotherm, pH effect, ionic strength effect and desorption were examined in batch experiments. The adsorption data fitted well to the Langmuir model with which the maximum P adsorption capacity was estimated to be 29.71 mg P/g. The amount of phosphate adsorbed increased rapidly in the first 5 h and slowly towards the end of the run, suggesting the possible monolayer coverage of phosphate ions on the surface of the adsorbent. The phosphate adsorption tended to increase with a decrease of pH and an increase of ionic strength. A phosphate desorbability of approximately 60% was observed with 0.5 M NaOH, which indicated a relatively strong bonding between the adsorbed PO{sub 4}{sup 3-} and the sorptive sites on the surface of the adsorbent. The immobilization of phosphate probably occurs by the mechanisms of ion exchange and physicochemical ...

2008-03-01

282

Regular frequency patterns in the classical delta Scuti star HD 144277 observed by the MOST satellite  

CERN Document Server

We present high-precision time-series photometry of the classical delta Scuti star HD 144277 obtained with the MOST (Microvariability and Oscillations of STars) satellite in two consecutive years. The observed regular frequency patterns are investigated asteroseismologically. HD 144277 is a hot A-type star that is located on the blue border of the classical instability strip. While we mostly observe low radial order modes in classical delta Scuti stars, HD 144277 presents a different case. Its high observed frequencies, i.e., between 59.9c/d (693.9 microHz) and 71.1c/d (822.8microHz), suggest higher radial orders. We examine the progression of the regular frequency spacings from the low radial order to the asymptotic frequency region. Frequency analysis was performed using Period04 and SigSpec. The results from the MOST observing runs in 2009 and 2010 were compared to each other. The resulting frequencies were submitted to asteroseismic analysis. HD 144277 was ...

2011-01-01

283

Radon Mapping of the Osijek Town  

International Nuclear Information System (INIS)

After ten years investigation of radon seasonal variations at three very different locations, as well as radon concentration measurements in kindergartens and schools, systematical indoor radon measurements were undertaken in dwellings of Osijek. Indoor radon was measured by means of the LR-115 nuclear track detector at 48 town locations that gave the arithmetic mean of 71.6 Bq m"-"3, standard deviation of 44.0 Bq m"-"3 and geometric mean of 60.1 Bq m"-"3, for the radon concentration range from 23 to 186 Bq m"-"3. The empirical frequency distribution of radon concentrations, with the class width of 20 Bq m"-"3, was in accordance with the theoretical log-normal distribution which was shown with #chi#"2 - test. The radon map pointed out a region of higher radon concentrations (central part of the town) that was ascribed to the geological soil structure. Thus supposition was confirmed by radon measurement in the soil gas using radon emanators with the LR-115 film that ...

1998-11-11

284

Prevalence of hepatosplenomegaly in beta thalassemia minor subjects in Iran  

Energy Technology Data Exchange (ETDEWEB)

Introduction: Thalassemia is the most common hereditary blood disorder in the world. Iran is located on the thalassemic belt and there is a high prevalence of the hepatosplenomegaly in beta thalassemia minor patients which is reported to be very variable. The goal of this research was to study the frequency of these signs in the cases with beta thalassemia minor patients in Iran. Materials and methods: Two hundred and fifty-nine cases that referred to center for pre-marriage tests were divided into two groups according to their MCV, MCH, and HbA2 (beta thalassemia minor cases and control groups). Liver and spleen sizes were determined by ultrasonographic method and the two groups were compared with each other. Results: Average spleen volumes in case and control groups were 163.48 {+-} 133.97 and 126.29 {+-} 53.98 mm{sup 3}, respectively. Average spleen lengths in case and control groups were 10.71 {+-} 1.52 and 10.60 {+-} 5.4 cm, respectively. Conclusion: In the ...

2009-01-15

285

Photorefractive keratectomy with mitomycin-C after corneal transplantation for keratoconus  

British Library Electronic Table of Contents (United Kingdom)

PurposeTo evaluate the efficacy of photorefractive keratectomy (PRK) for residual refractive error after penetrating keratoplasty (PKP) for keratoconus. SettingPrivate ophthalmic clinic. DesignCase series. MethodConsecutive patients who had PRK augmented with topical mitomycin-C (MMC) after PKP for keratoconus were retrospectively reviewed. Patients were divided into a a low cylinder group (refractive cylinder 6.00 D). Visual acuity, refraction, and keratometry were analyzed preoperatively and 1, 3, 6, and 12 months postoperatively. ResultsThe study comprised 47 eyes (41 patients). The spherical equivalent (SE) decreased from -4.24 D +- 3.23 (SD) preoperatively to -0.71 +- 1.03 D 12 months postoperatively in the low cylinder group and from -4.19 +- 3.54 D to -2.45 +- 3.42 D, respectively, ...

2011-01-01

286

Parametric study of pipe whip analysis  

Energy Technology Data Exchange (ETDEWEB)

In the Energy Balance Analysis Model (Standard Review Plan (USNRC, 1981), Section 3.6.2, ''Determination of Rupture Locations and Dynamic Effects Associated with the Postulated Rupture of Piping''), time dependence is not considered, and a constant blowdown thrust force is assumed. This force includes an amplification factor of 1.1 to account for potential effects of rebound. Many of the assumptions used in establishing the acceptance criteria, as stated in the Standard Review Plan, were based on engineering judgment and logic intended to assure upper bound design rather than on a mechanistic assessment of actual pipe rupture phenomena and their effects. As a result of the current practice an exceedingly conservative design may be introduced. This report represents a parametric study of the amplification factor to account for rebound effects in the Energy Balance Method. Of the 71 distinct cases we chose for our parametric study, ...

1987-10-01

287

Morphological development of larval cobia Rachycentron canadum and the influence of dietary taurine supplementation  

British Library Electronic Table of Contents (United Kingdom)

The morphological development of larval cobia Rachycentron canadum from 3 days post hatch (dph) until weaning (27 dph) was examined using S.E.M. Two groups of fish were studied: a control group (CF), reared under standard feeding protocol, and a group in which prey items were enriched with supplemental taurine (4 g l-1 day-1; TF). TF fish grew faster (P < 0001), attained greater size (mean s.e. 551 15 v. 339 10 mm total length) and had better survival (mean s.e. 293 04 v. 71 12 %) than CF fish. Canonical variance analysis confirmed findings with respect to differences in growth between the treatment groups with separation being explained by two cranial measurements. S.E.M. revealed that 3 dph larvae of R. canadum (in both groups) possess preopercular spines, superficial neuromasts on the h...

2011-01-01

288

Mechanical properties of Fe -10Ni -7Mn martensitic steel subjected to severe plastic deformation via cold rolling and wire drawing  

Energy Technology Data Exchange (ETDEWEB)

Fe-Ni-Mn martensitic steels are one of the major groups of ultra-high strength steels that have good mechanical properties and ductility in as annealed condition but they suffer from severe inter-granular embitterment after aging. In this paper, the effect of heavy shaped cold rolling and wire drawing on the mechanical properties of Fe-Ni-Mn steel was investigated. This process could provide a large strain deformation in this alloy. The total strain was {epsilon} {approx}7. Aging behavior and tensile properties of Fe-10Ni-7Mn were studied after aging at 753 K. The results showed that the ultimate tensile strength and ductility after cold rolling, wire drawing and aging increased up to 2540 MPa and 7.1 %, respectively, while the conventional steels show a premature fracture stress of 830 MPa with about zero ductility after aging.

2010-07-01

289

Mechanical properties of Fe -10Ni -7Mn martensitic steel subjected to severe plastic deformation via cold rolling and wire drawing  

International Nuclear Information System (INIS)

Fe-Ni-Mn martensitic steels are one of the major groups of ultra-high strength steels that have good mechanical properties and ductility in as annealed condition but they suffer from severe inter-granular embitterment after aging. In this paper, the effect of heavy shaped cold rolling and wire drawing on the mechanical properties of Fe-Ni-Mn steel was investigated. This process could provide a large strain deformation in this alloy. The total strain was #epsilon# #approx#7. Aging behavior and tensile properties of Fe-10Ni-7Mn were studied after aging at 753 K. The results showed that the ultimate tensile strength and ductility after cold rolling, wire drawing and aging increased up to 2540 MPa and 7.1 %, respectively, while the conventional steels show a premature fracture stress of 830 MPa with about zero ductility after aging.

2010-07-01

290

Mass and charge distributions in the very asymmetric thermal neutron induced fission of the odd-Z nucleus {sup 242m}Am  

Energy Technology Data Exchange (ETDEWEB)

Yields of light fission products (A = 68, 70-84, 87, 88, 94, 96, 98, 102 and 106-108), their kinetic energies and nuclear charge distributions (A 71-84, 87 and 88) in the thermal neutron induced fission of the odd-Z nucleus {sup 242m}Am(Z = 95) were measured using the mass-separator Lohengrin at the Institute Laue-Langevin in Grenoble (France). The mass yield curve shows a fine structure at A = 70, probably due to shell and/or odd-even effects affecting also the nuclear charge distribution. The analysis of isotopic chain yields gives evidence for a very low excitation energy of the lightest fission fragments observed. A preferential formation of fragments with even Z is found for this odd-Z compound nucleus. Calculated values for the local odd-even effect are comparable with those for the neighbouring even-Z fissile nuclides and increase from 13% to 30% with increasing asymmetry of the mass split (A{sub L} = 84 to 68 and Z{sub L} = 35 to 28). The neutron odd-even ...

1999-10-25

291

MRT versus CT in the diagnosis of pneumonia. Evaluation of a T_2-weighted utrafast turbo-spin-echo sequence (UTSE)  

International Nuclear Information System (INIS)

Purpose: To evaluate a T_2-weighted URSE sequence for the assessment of pulmonary infiltrations in comparison to CT. Methods: 28 MRT scans of 22 patients with confirmed pneumonia were recorded on a 1.5 Tesla apparatus with an expiratory and diastolic triggered, T_2-weighted ultrafast-spin-echo sequence in axial slice mode with the following parameters: TR_e_f_f/T_E/Turbofactor 2000-4000/90 ms/21-23; slice thickness/separation 6/0.6 mm; FOV 360 mm; 24 slices. 24 spiral CTs (sice thickness/table advance: 1-2 mm/10 mm) were available for comparison. The separate evaluation of MRTs and CTs was performed by three radiologists in a consensus procedure with regard to pulmonary lesions (e.g., infiltration, round foci, net patterns) and image quality of the MRTs (4-step scale). Results: In 71% of the cases the CTs and MRTs agreed with the diagnosis and representation of the lesions, in 25% MRT was superior. MRT was better for the detection of pulmonary abscesses. In 93% the ...

1999-05-01

292

MRI in definition of bleeding source, lesion pattern and therapy in haemarthros of the knee  

International Nuclear Information System (INIS)

Patients with haemarthros of the knee were examined by MRI and arthroscopy to identify the bleeding source and to determine surgical or conservative therapy. A prospective study was performed on 120 patients who underwent MRI and arthroscopy, point lesions and bleeding sources were documented separately on a standardised form. Arthroscopy demonstrated a ruptured anterior cruciate ligament in 86%, meniscal tears in 55%, disruption of collateral ligaments in 17%, osteochondral lesions in 5% and tears of capsule or plicae in 13%. Disruption of cruciate ligaments caused haemorrhage in all but three cases. In contrast, only meniscal tears located very adjacent to the meniscal basement had bled. Those types of osteochondral lesions caused haemorrhage characterised on MRI by destruction of the subchondral plate and overlying cartilage. Severe lesions of the knee were diagnosed by MRI in 71% to 100%, slight lesions in 13% to 40% of the cases. Single, combined and bland ...

293

M X-ray production in Nd, Gd, Ho and Lu by 1-6 MeV lithium ions  

Energy Technology Data Exchange (ETDEWEB)

M-shell X-rays of the rare-earth elements {sub 60}Nd, {sub 64}Gd, {sub 67}Ho and {sub 71}Lu were measured for lithium ion bombardment in the energy range 1.0-6.0 MeV. The M-shell X-rays with energies of 0.978-1.631 keV were detected with a LINK analytical detector. The efficiency of the detector was determined by using the known atomic-field bremsstrahlung cross-sections from low energy electron beams and K-shell X-ray measurements with light projectiles. The measured cross-sections are compared to the predictions of the first Born approximation and the ECPSSR (energy loss and Coulomb deflection effects, perturbed stationary state approximation with relativistic correction) theories. The best theoretical description of the present data is given by the ECPSSR theory, even though the discrepancy between data and theory is increasing at higher projectile energies.

2004-06-01

294

Heat transfer augmentation in a rectangular channel with a vee-shaped vortex generator  

International Nuclear Information System (INIS)

The unsteady flow and heat transfer are simulated using LES and DNS for a channel with two angled ribs as a vee-shaped vortex generator to augment heat transfer. The vortex generators are attached on the bottom wall of the channel and their angles in respect to the main flow are between 10"o and 30"o. The Prandtl number is 0.71 and the Reynolds numbers based on the inflow velocity and the height of channel are from 200 to 2000. Based on the results of this work, the variations of the Nusselt number, pressure coefficient, bulk temperature, friction factor and Colburn factor with the Reynolds numbers and the incidence angles are provided. The relation between the key parameters of the velocity (friction factor f) and thermal (Colburn factor J) boundary layers is calculated for all cases and their values are compared with the predicted values by the Chilton-Colburn analogy. A comparison between the DNS and LES results is performed and it is found that relatively ...

2007-04-01

295

Heat transfer augmentation in 3D internally finned and microfinned helical tube  

Energy Technology Data Exchange (ETDEWEB)

Experiments are performed to investigate the single-phase flow and flow-boiling heat transfer augmentation in 3D internally finned and micro-finned helical tubes. The tests for single-phase flow heat transfer augmentation are carried out in helical tubes with a curvature of 0.0663 and a length of 1.15 m, and the examined range of the Reynolds number varies from 1000 to 8500. Within the applied range of Reynolds number, compared with the smooth helical tube, the average heat transfer augmentation ratio for the two finned tubes is 71% and 103%, but associated with a flow resistance increase of 90% and 140%, respectively. A higher fin height gives a higher heat transfer rate and a larger friction flow resistance. The tests for flow-boiling heat transfer are carried out in 3D internally micro-finned helical tube with a curvature of 0.0605 and a length of 0.668 m. Compared with that in the smooth helical tube, the boiling heat transfer coefficient in the 3D internally ...

2005-05-01

296

Development and performance of a miniature, high-voltage thermal battery  

Science.gov (United States)

A miniature, high-voltage, thermally activated battery has been developed. This battery weighs 41 grams, occupies a volume of 16.4 cu cm, and contains two separate 500-v channels, each designed to charge a 5.25 microfarad capacitor within 300 milli-seconds and remain operational under a 640-kohm load for a minimum of 28 seconds over the temperature range from +16 to +71 C. The electrochemical system utilizes a calcium anode, LiCl-KCl molten salt electrolyte, a CaCrO4-K2CrO4 mixture as the depolarizer or active cathode material, and an iron cathode. The depolarizer and electrolyte, along with a silica binder, are formed into homogeneous pellets, and these pellets are stacked alternately with calcium-iron bimetal disks in beryllium oxide tubes to form cell stacks. The cells are activated by an iron-potassium perchlorate pyrotechnic heat source external to the BeO tubes.

1974-01-01

297

Design and performance of a solar-powered air-conditioning system in a green building  

Energy Technology Data Exchange (ETDEWEB)

A solar-powered adsorption air-conditioning system was designed and installed in the green building of Shanghai Research Institute of Building Science. The system contained 150 m{sup 2} solar collectors and two adsorption chillers with nominal refrigeration capacity of 8.5 kW. Based on performance characteristics of the adsorption chiller, the operation mode of the solar-powered air-conditioning system was optimized by maintaining a phase shift of 540 s between the two adsorption chillers. Thereafter, the whole system realized stable operation by the balance of heat consumption and refrigeration output. From June to August of 2005, the solar-powered air-conditioning system continuously ran between 9:00 and 17:00. The operation performance of the system under representative working condition showed that the average refrigeration output of the solar-powered air-conditioning system was 15.3 kW during an 8 h operation and the maximum value exceeded 20 kW. Solar fraction for the system in ...

2008-05-15

298

Corrosion on stainless steel in high concentrated sulphuric acid under flow- and fatigue loading conditions. Stroemungs- und schwingungsbeeinflusste Korrosion von nichtrostenden Staehlen in konzentrierter Schwefelsaeure; Schlussbericht  

Energy Technology Data Exchange (ETDEWEB)

It was to be investigated why inexplicable cracking occurred in plain stainless austenitic steel pipes of heat exchangers in discrete sites of the inner surface exposed to acid even with anodic corrosion protection, and what countermeasures must be taken. The following materials were investigated: X 6 CrNiTi 18 10 and X 6 CrNiMoTi 17 12 2. The influence of mechanical vibrations on passive film formation and destruction was investigated in unconstrained pipes and pipes constrained at one end in conditions of anodic protection at frequencies of 0 to 160 Hz and temperatures of 98 to 130 degrees Centigrade in 98% sulphuric acid. The authors were unable to reconstruct the cracks observed in practical operation in anodically protected heat exchanger pipes of stainless austenitic steel. (orig./MM). 5 refs., 2 tabs., 71 figs.

1990-09-20

299

Characterization of atmospheric emissions produced by live gun firing : test on the M777 155 mm Howitzer  

Energy Technology Data Exchange (ETDEWEB)

This study analyzed the atmospheric emissions produced by the live firing of a 155 mm Howitzer gun. The study was conducted during a live firing training exercise at a Canadian Forces Base. Air emissions were sampled continuously for 3 hours. Particles and chemicals were accumulated on sampling media during the firing of 69 rounds. A single round was fired using 4 bags of propellants, and an additional 3 rounds were fired using 5 bags of propellant. Samples included particulate matter; hydrogen cyanide; polycyclic aromatic hydrocarbons (PAHs); dinitrotoluene compounds; benzene; toluene; ethylbenzene; xylene; metals; aldehydes; nitric acid; nitric oxide; nitrogen dioxide; hydrogen sulphide; and sulphur dioxide. Samples were collected at 8 m to the left of the gun as well as at 22 m in front of the gun muzzle in the line of fire. Results of the study showed that 60 per cent of the particles were below 10 {mu}m. Formaldehyde concentrations of 7.1 and 3.6 {mu}g/m{sup ...

2007-10-15

300

Bronchoalveolar lavage in systemic sclerosis with lung involvement: role and correlations with functional, radiological and scintigraphic parameters  

British Library Electronic Table of Contents (United Kingdom)

To evaluate the role and the prognostic value of bronchoalveolar lavage (BAL) in scleroderma patients with interstitial lung disease. We reviewed the records of 79 patients with systemic sclerosis (SSc) who had dyspnea and pulmonary involvement and underwent BAL study. Sixty-two patients were prospectively followed up for 12?36?months and re-evaluated by pulmonary function tests (PFTs). Seventy-nine SSc patients were enrolled (71 F and 8?M), 55 with limited and 24 with a diffuse form; mean age 55???13?years; mean disease duration 55.2???59?months. All patients were ANA positive, of these 30 were anti-topoisomerase-1 positive (anti-Topo1) and 22 were anti-centromere positive (ACA). Thirty-one patients had alveolitis (39.2%) that was neutrophilic in 12 patients, eosinophilic in 3 and mixed (...

2011-01-01

301

Assessment of internal dose by {sup 3}H and {sup 14}C of total diet for inhabitants near Wolsung nuclear power plants  

Energy Technology Data Exchange (ETDEWEB)

To assess the internal dose by {sup 3}H and {sup 14}C in total diet of inhabitants near Wolsung nuclear power plants, TFWT, OBT and {sup 14}C concentration in total diet was analyzed for collection region and time. TFWT, OBT and {sup 14}C concentrations were in the range of 3.19-42.2 Bq/L, 1.00-39.4 Bq/L, and 0.230-0.856 Bq/gC, respectively. The calculated annual effective dose with TFWT, OBT and {sup 14}C is 6.10 x 10{sup -5} mSv/y, 3.71 x 10{sup -5} mSv/y and 7.08 x 10{sup -3} mSv/y, respectively. And then annual internal dose with total diet for inhabitants near Wolsung NPPs is about 7.18 x 10{sup -3} mSv/y, which is about 0.72% of annual effective dose limit 1 mSv/y.

2003-03-15

302

Assessment of internal dose by "3H and "1"4C of total diet for inhabitants near Wolsung nuclear power plants  

International Nuclear Information System (INIS)

To assess the internal dose by "3H and "1"4C in total diet of inhabitants near Wolsung nuclear power plants, TFWT, OBT and "1"4C concentration in total diet was analyzed for collection region and time. TFWT, OBT and "1"4C concentrations were in the range of 3.19-42.2 Bq/L, 1.00-39.4 Bq/L, and 0.230-0.856 Bq/gC, respectively. The calculated annual effective dose with TFWT, OBT and "1"4C is 6.10 x 10"-"5 mSv/y, 3.71 x 10"-"5 mSv/y and 7.08 x 10"-"3 mSv/y, respectively. And then annual internal dose with total diet for inhabitants near Wolsung NPPs is about 7.18 x 10"-"3 mSv/y, which is about 0.72% of annual effective dose limit 1 mSv/y.

2003-03-01

303

Analysis of pesticides in dried hops by liquid chromatography-tandem mass spectrometry.  

Science.gov (United States)

An analytical method was developed for the determination of eleven agrochemicals [abamectin (as B1a), bifenazate, bifenthrin, carfentrazone-ethyl, cymoxanil, hexythiazox, imidacloprid, mefenoxam, pymetrozine, quinoxyfen, and trifloxystrobin] in dried hops. The method utilized polymeric and NH2 solid phase extraction (SPE) column cleanups and liquid chromatography with mass spectrometry (LC-MS/MS). Method validation and concurrent recoveries from untreated dried hops ranged from 71 to 126% for all compounds over three levels of fortification (0.10, 1.0, and 10.0 ppm). Commercially grown hop samples collected from several field sites had detectable residues of bifenazate, bifenthrin, hexythiazox, and quinoxyfen. The control sample used was free of contamination below the 0.050 ppm level for all agrochemicals of interest. The limit of quantitation and limit of detection for all compounds were 0.10 and 0.050 ppm, respectively. PMID:18593182

2008-07-02

304

A preliminary study of a cartoon measure for children's reactions to chronic trauma.  

Science.gov (United States)

Preliminary psychometric properties of a new instrument, Angie/Andy Cartoon Trauma Scales (ACTS), are presented. Angie/Andy features a cartoon-based methodology, measuring trauma-related sequelae of prolonged, repeated abuse. A sample of 208 children comprised intrafamilial trauma, extrafamilial trauma, combined trauma, and nontrauma groups. Angie/Andy demonstrated high internal consistency, with coefficient alphas from 0.70 to 0.95. The three trauma groups scored significantly higher than the nontrauma group on all scales (p's < 0.0001). Generally, the most severely traumatized group scored significantly higher than the less severely traumatized groups. The number of types of violence exposures correlated with Angie/Andy scores from 0.55 to 0.74. The frequency and severity of trauma exposure correlated with Angie/Andy scores from 0.44 to 0.56. The Angie/Andy parent version correlated with a standardized parent scale from 0.71 to 0.81. Parent/child agreement was ...

2000-08-01

305

Radioactive targets for neutron-induced cross section measurements  

Science.gov (United States)

Measurements using radioactive targets are important for the determination of key reaction path ways associated with the synthesis of the elements in nuclear astrophysics (sprocess), advanced fuel cycle initiative (transmutation of radioactive waste), and stockpile stewardship. High precision capture cross-section measurements are needed to interpret observations, predict elemental or isotopical ratios, and unobserved abundances. There are two new detector systems that are presently being commissioned at Los Alamos National Laboratory for very precise measurements of (n,{gamma}) and (n,f) cross-sections using small quantities of radioactive samples. DANCE (Detector for Advanced Neutron-Capture Experiments), a 4 {pi} gamma array made up of 160 BaF{sub 2} detectors, is designed to measure neutron capture cross-sections of unstable nuclei in the low-energy range (thermal to {approx}500 keV). The high granularity and high detection efficiency of DANCE, combined with ...

2004-01-01

306

Relationship between hemodynamic response to exercise and distribution of pulmonary perfusion in mitral stenosis  

Energy Technology Data Exchange (ETDEWEB)

Relationship between hemodynamic response to exercise and distribution of pulmonary perfusion was studied in 71 patients with mitral stenosis. Distribution was estimated by using computerized Tc-99m-MAA perfusion images (digital perfusion images; DPI). DPI were composed of isocount areas. Various types of DPI were obtained and were classified to 6 grades (G) according to patterns of 100 - 70% isocount area in right anterior DPI, i.e. G-0 (normal), G-1 (increase of perfusion at upper zone), G-2 (uniform distribution), G-3 (disappearance of basal hyperperfusion area), G-4 (apical hyperperfusion area) and G-5 (decrease of perfusion at lower zone). Patients were devided to 4 groups according to grade. At rest there were no marked hemodynamic differences between groups (n = 71, mean pulmonary artery pressure (mPA); 24.8 +- 11.0 mmHg, cardiac index (CI); 2.7 +- 0.81 lmM/sup 2/), however hemodynamic parameter during exercise showed marked differences, ...

1987-11-01

307

Comparison of histological findings and parathyroid scintigraphy in hemodialysis patients with secondary hyperparathyroid glands  

International Nuclear Information System (INIS)

The objective of this study was to determine the usefulness of parathyroid scintigraphy in histological estimation for secondary hyperparathyroidism (2HPT) using Tc-99m sestamibi or Tc-99m tetrofosmin. Tc-99m sestamibi (MIBI) and Tc-99m tetrofosmin (Tetro) parathyroid imaging following double-phase study, magnetic resonance imaging (MRI), and ultrasound were performed on 14 patients with 2HPT. All patients underwent parathyroidectomy. The uptake of two tracers in parathyroid areas was compared with the histopathologic findings. Forty-nine parathyroid glands were surgically explored and histologically proven to be hyperplastic. Of these, 42 were diagnosed with nodular type (N-type) hyperplasia, and 7 with diffuse type (D-type) hyperplasia. MIBI and Tetro parathyroid imagings detected 34 and 35 parathyroid glands, respectively. The sensitivity of MIBI was determined to be 76.2% (32/42) for N-type, and 28.6% (2/7) for D-type. The sensitivity of Tetro was determined to be 78.6% (33/42) for ...

2005-04-01

308

Simultaneous production of "2"8Mg and "4"7Ca by high-energy heavy-ion irradiation for applications in biology  

International Nuclear Information System (INIS)

With the aim of preparing carrier-free "2"8Mg and "4"7Ca simultaneously, Ti, V and Fe targets were examined by irradiating with high-energy ions of "1"2C, "1"4N and "1"6O accelerated by the RIKEN ring cyclotron. Among the targets, V gave the highest cross section for the formation of both "2"8Mg and "4"7Ca irrespective of the kind of beams. The cross section for the formation of "2"8Mg by the reactions of Ti, V and Fe targets with ion beams increased in the order of "1"2C<"1"6O<"1"4N. On the other hand, the three beams exhibited almost the same cross sections for the formation of "4"7Ca by the reaction of a given target. Titanium and V were selected as prospective targets and "1"4N as a suitable beam for the production of "2"8Mg and "4"7Ca. Chemical separation procedures of the radiotracers in carrier- and salt-free states have been established by using cation exchange resins. ...

309

SiO{sub 2}-Ta{sub 2}O{sub 5} sputtering yields: simulated and experimental results  

Energy Technology Data Exchange (ETDEWEB)

To improve mirrors coating, we have modeled sputtering of binary oxide targets using TRIM code. First, we have proposed a method to calculate TRIM input parameters using on the one hand thermodynamic cycle and on the other hand Malherbe`s results. Secondly, an iterative processing has provided for oxide steady targets caused by ionic bombardment. Thirdly, we have exposed a model to get experimental sputtering yields. Fourthly, for (Ar - SiO{sub 2}) pair, we have determined that steady target is a silica one. A good agreement between simulated and experimental yields versus ion incident angle has been found. For (Ar - Ta{sub 2} O{sub 5}) pair, we have to introduce preferential sputtering concept to explain discrepancy between simulation and experiment. In this case, steady target is tantalum monoxide. For (Ar - Ta+O{sub 2}) pair, tantalum sputtered by argon ions in reactive oxygen atmosphere, we have to ...

1994-09-01

310

Measurement of K x-ray intensity ratio of tin, gadolinium and dysprosium  

International Nuclear Information System (INIS)

Full text: Measurement of K_#beta# to K_#alpha# x-ray intensity ratios are important not only in the field of atomic physics, radiation physics and medical physics, but also to test the validity of assumptions made in the theoretical prediction. The intensity ratios can also give information on the effect of physical and chemical environment of the element in the compound. Many investigators have adopted a single and double reflection geometries to measure the K_#beta# to K_#alpha# x ray intensity ratios to understand the effect of physical and chemical environment on x-ray fluorescence. The targets are excited by a radioactive source of having activity of the order 100 MBq. in order to carry out accurate measurement K_#beta# to K_#alpha# x-ray intensity ratios, we have develop 2#pi# geometrical configuration method : placing a target right on the surface of the detector facing the target to measure the K shell fluorescence ...

2003-11-01

311

Variational method for estimating the rate of convergence of Markov Chain Monte Carlo algorithms  

CERN Document Server

We demonstrate the use of a variational method to determine a quantitative lower bound on the rate of convergence of Markov Chain Monte Carlo (MCMC) algorithms as a function of the target density and proposal density. The bound relies on approximating the second largest eigenvalue in the spectrum of the MCMC operator using a variational principle and the approach is applicable to problems with continuous state spaces. We apply the method to one dimensional examples with Gaussian and quartic target densities, and we contrast the performance of the basic Metropolis-Hastings algorithms with a ``smart'' variant that incorporates gradient information into the trial moves. We find that the variational method agrees quite closely with numerical simulations. We also see that the smart MCMC algorithm often fails to converge geometrically in the tails of the target density except in the simplest case we examine, and even then care ...

2006-01-01

312

Transmission nuclear resonance fluorescence measurements of "2"3"8U in thick targets  

International Nuclear Information System (INIS)

Transmission nuclear resonance fluorescence measurements were made on targets consisting of Pb and depleted U with total areal densities near 86g/cm"2. The "2"3"8U content in the targets varied from 0% to 8.5% (atom fraction). The experiment demonstrates the capability of using transmission measurements as a non-destructive technique to identify and quantify the presence of an isotope in samples with thicknesses comparable to the average thickness of a nuclear fuel assembly. The experimental data also appear to demonstrate the process of notch refilling with a predictable intensity. Comparison of measured spectra to previous backscatter "2"3"8U measurements indicates general agreement in observed excited states. Evidence of two new "2"3"8U excited states and possibly a third state have also been observed.

2011-05-15

313

The influence of chemically active gas on the light emission of metallic targets bombarded by positive ions  

International Nuclear Information System (INIS)

The introduction of oxygen in the vicinity of a metallic target surface, bombarded with positive argon ions of twenty kiloelectron-volts, increases the number of sputtered atoms in the excited state. This phenomenon of exaltation, very sensitive in the case of nickel and aluminium, is much less marked in the case of molybdenum. Moreover, the emission of excited particles coming from the beam's ions is not modified. A quantum-mechanical model of a kinetic emission process, which permits the interpretation of the clean metallic target's emission phenomena, seems insufficient to explain all of the results obtained in the presence of oxygen. In this last case one can therfore use a thermodynamic model in which excited metallic particles can be formed directly by chemical surface reactions of neutralization or reduction. (orig.).

314

Targeting the nicotinic alpha7 acetylcholine receptor to enhance cognition in disease  

British Library Electronic Table of Contents (United Kingdom)

A promising drug target currently under investigation to improve cognitive deficits in neuropsychiatric and neurological disorders is the neuronal nicotinic alpha7 acetylcholine receptor (a7nAChR). Improving cognitive impairments in diseases such as Alzheimer's (AD) and schizophrenia remains a large unmet medical need, and the a7nAChR has many properties that make it an attractive therapeutic target. The a7nAChR is a ligand gated ion channel that has particularly high permeability to Ca^2^+ and is expressed in key brain regions involved in cognitive processes (e.g., hippocampus). The a7nAChRs are localized both pre-synaptically, where they can regulate neurotransmitter release, and post-synaptically where they can activate intracellular signaling cascades and influence downstream processes...

2011-01-01

315

Targeted drug delivery under MRI guidance  

British Library Electronic Table of Contents (United Kingdom)

The main goal of local drug delivery is to increase the concentration of a specific therapeutic agent in a target tissue with minimal nontarget distribution. Compared to systemic therapy, local drug delivery provides a high level of therapeutic efficacy with minimal systemic effects. The current primary imaging modality for drug delivery has been x-ray angiography, but it has major limitations including anatomical ambiguity and inability to visualize the targeted tissues. Due to these inherent problems, MR guidance has been explored as an alternative imaging modality for guiding and monitoring of drug therapy. Recently, interventional MR (XMR) systems have been implemented that have both dual x-ray and MRI capabilities in a single suite and allow for real-time interventional procedures to ...

2008-01-01

316

Study on possible fuel layering sequence for FIREX target  

International Nuclear Information System (INIS)

A new procedure of fuel layering for the Fast Ignition Realization Experiment (FIREX) target is proposed. A conical laser guide heating technique was experimentally demonstrated in principle as the followings. It employed the target consisting of a polystyrene (PS) shell, a fill tube and a conical laser guide. At first, liquid fuel was fed into the shell and existed around the conical laser guide because the surface tension of the fuel must cause it. Then, it was solidified. The laser light provided a heat source to the conical laser guide so that the solid fuel was moved to the other interior of the shell. This process resulted in missing solid fuel around the conical laser guide. To fill the vacant space, liquid fuel was added as temperature was raised to the melting point. After the liquid fuel addition, temperature was lowered to the solidification point again. During this process, most of the solid fuel could survive.

2010-08-01

317

Studies on heterogeneous simulated Am targets. Influence of lanthanide oxides  

Energy Technology Data Exchange (ETDEWEB)

Targets for heterogeneous transmutation of americium are composed of a support material, the inert matrix and of an americium oxide compound: AmO{sub 2-x} or Am{sub 2}O{sub 3}. In parallel to the studies using americium, simulated compounds of americium oxide, chosen amongst lanthanide oxides, are used. The selection of these compounds is based on theoretical, physical and crystallochemical considerations. In order to assess the influence of impurities composed of lanthanide oxides, resulting from the separation process, on the physical and chemical properties of such a target, synthesis of oxide powders containing impurities associated with the simulated americium oxide, characterizations, crystallographic studies and sodium compatibility tests have been performed. (author)

1997-12-31

318

Studies of L x-rays from 64 MeV iodine projectiles in collision with gas targets  

International Nuclear Information System (INIS)

We have studied L x-rays from 64 MeV iodine projectile in collision with various gas targets, Z_2 #18, do not arise from selective M subshell vacancy population, has been conclusively established by the observations by Datz et al (1971) and by Saha et al (1996) that the measured intensity ratio of the Ll and L#alpha# lines, which arise because of transitions from different M subshells into the same L, subshell, does not show any periodic behaviour with Z, but stays rather constant. Differences in the measured L#beta#_1/L#alpha# intensity ratio of iodine with 7"+ and 24"+ charge states impinging on Kr target established the minor role of the electrons in the N shell of the projectile in the x-ray production mechanism. (author)

1997-11-17

319

Some properties of atomic beam produced by laser induced ablation of Li target  

International Nuclear Information System (INIS)

Pulsed atomic beams produced in vacuum by laser induced ablation from a lithium target are analyzed by laser induced fluorescence (LIF). The 1-mixing processes induced in the n = 9, 10 Li Rydberg states by collisions with CO_2 molecules illustrate the application of the method. Resolution is limited by the 1 mm diameter of the probe laser beam. Combining LIF and absorption measurements gives n_L_i as a function of time at various distances from the target surface. The investigation of the Li-C0_2 1-mixing process in a heat pipe oven proved impossible due to the high reactivity of Li with C0_2. This problem was solved by renewing the Li atoms at each laser shot. Values obtained for n = 9, n = 10 are k = 17 x 10"-"8 and 15 x 10"-"8 cc/sec, respectively.

320

Separation of {sup 187,188}Pt and {sup 187,188}Ir produced in {sup 11}B{sup 4+} irradiated tantalum target  

Energy Technology Data Exchange (ETDEWEB)

Heavy ion irradiation on tantalum metal target with 57 MeV {sup 11}B{sup 4+} leads to the production of no-carrier-added radioisotopes of platinum, {sup 187,188}Pt and iridium, {sup 187,188}Ir in the matrix, which have been effectively separated from the bulk target and from each other with suitable anion exchangers employing liquid-liquid extraction (LLX). Also {sup 188,189}Pt and {sup 188,189}Ir radionuclides have been produced, from their short-lived precursors {sup 188,189}Au, in {sup 12}C{sup 6+} irradiated tantalum matrix. Gamma-spectroscopy has been utilised to determine the production, extent of separation and purity of the radiotracers at different stages of the experiment. (orig.)

2000-07-01

321

Particle emission from low energy proton bombardment of TiH{sub 2} and TiD{sub 2}  

Energy Technology Data Exchange (ETDEWEB)

TiH{sub 2} and TiD{sub 2} thick targets were bombarded with 100 to 200 keV protons. Evidence for nuclear reactions was obtained by means of a surface barrier particle detector. Proton irradiation of TiD{sub 2} produced the following observations: {alpha} particle emission identified as (p, {alpha}) reactions from {sup 11}B and {sup 7}Li impurities in the target at ppm concentrations; and {approx}3 MeV proton and {approx}1 MeV triton emission from secondary D-D reactions caused by elastic scattering of the primary proton with a target deuteron. A 3.9 MeV {alpha} particle peak measured by others was not observed. (author)

2002-03-01

322

PIC Simulations Of Ion Acceleration By Linearly And Circularly Polarized Laser Pulses  

Science.gov (United States)

Linearly polarized laser radiation accelerates electrons to very high velocities and these electron form a sheath layer on the rear side of thin targets where preferentially protons are accelerated. When mass-limited targets are used, the lateral transport of the absorbed laser energy is reduced and the accelerating field is enhanced. For targets consisting of two ion species, heavier ions facilitate formation of quasi-monoenergetic bunch of lighter ions. For circularly polarized light, fast electron production is suppressed by the absence of the oscillatory component of the ponderomotive force. Ions are accelerated on the front side by the separation field and very thin foil can be accelerated as one massive quasi-neutral block. As all ion species acquire the same velocity, this acceleration mechanism is preferred for heavier ions.

2008-06-24

323

Natural convection cooling of the IFMIF target and test cell  

International Nuclear Information System (INIS)

The present work summarizes efforts on the simulation of natural convection cooling within the IFMIF target and test cell. The simulations have been performed with the STAR-CD code using the k-#omega# high-Reynolds number turbulence model. A dedicated thermohydraulic model has been devised including Lithium loop components. Nuclear heat production has been calculated by the Monte-Carlo code McDeLicious for different parts of the target and test cell walls and was used as input for the STAR-CD simulations. Helium atmospheres at several pressures from 0.1 to 10"-"5 MPa have been investigated. In order to limit the maximum temperature of the concrete walls to 80 deg. C it was necessary to add thermal insulation layers to the hot Lithium loop surfaces and a conceptual system of two cooling layers in different depths of the concrete walls.

2007-10-01

324

Inelastic excitation in the collisions of relativistic heavy ions  

International Nuclear Information System (INIS)

The penumbra of the profile function describing the nuclear collisions of relativistic heavy ions is related to the cross section for their producing a specific target-nucleus #gamma#-ray, sigmasub(#gamma#). The analysis assumes that the diffuse-edge diffraction model suffices to calculate the inelastic cross sections to the particle-stable states of the target nucleus. When the deformation lengths, deltasub(L) = #beta#sub(L)R, characterizing all important excitations are available from other experiments and the #gamma#-branching of these states is also known, the only unknown quantity determining sigmasub(#gamma#) is found to be the ratio of the diffuseness parameter of the profile function, d, to its radius, R. The most reliably determined values of d/R, for the target "4"0Ca, imply a rather wide penumbra, consistent with microscopic calculations. (orig.).

325

Improvement of tracking performance using prediction-based algorithms for a maneuvering target  

British Library Electronic Table of Contents (United Kingdom)

This paper presents a study involving prediction of a complicated maneuvering target, with the aim of improving the tracking performance of a fire control system (FCS). In this study, we predict the position of a complicated maneuvering target 5 s in advance using the information up to the current time. Because of the large error caused by the complicated maneuvers and the long prediction time interval, the mechanical system of the fire control system will take a heavy load. In order to cope with this problem, several approaches to decreasing the prediction error have been proposed including the prediction algorithms based on the multiple model(MM) filter, interacting multiple model (IMM) filter, and variable dimension with input estimation (VDIE) filter. Finally, comparative simulation re...

2011-01-01

326

Hyperspectral remote sensing for mineral exploration in Pulang, Yunnan Province, China  

British Library Electronic Table of Contents (United Kingdom)

The launch of the first spaceborne hyperspectral instrument, Hyperion, in 2000 has provoked further research into its capabilities with regard to mineral exploration. Our study in the remote, mountainous region of Pulang, China employed a two-step progressive approach, first to locate target areas characterized by hydrothermal mineral alteration, using the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER), and secondly, to attempt detailed mineral mapping using Hyperion. The preliminary target detection involved principal components and broad-band spectral analysis and led to the detection of two target areas characterized by argillic alteration, iron-oxide- and sulphate-bearing minerals. A focused hyperspectral study followed using Spectral Angle Mapper (SAM) and Mixt...

2011-01-01

327

Detached divertor plasmas in JET  

Energy Technology Data Exchange (ETDEWEB)

In simulations with high radiated power fractions, it is possible to produce the drop in ion current to the divertor targets typical of detached plasmas. Despite the fact that these experiments are performed on beryllium target tiles, radiation from deuterium and beryllium cannot account for the measured power losses. The neutral deuterium levels in the SOL in these plasmas are higher than the model predicts. This may be due to leakage from the divertor or to additional wall sources related to the non-steady nature of these plasmas. In contrast, a surprisingly high level of carbon is present in these discharges; higher even than would be predicted are the divertor target tiles pure carbon. This level may well be large enough to produce the measured radiation. (authors). 6 refs., 2 figs., 1 tab.

1994-07-01

328

Analysis of neutron emission spectra for 30-50 MeV #alpha#-particle induced reactions in thick targets  

International Nuclear Information System (INIS)

Comparisons of calculated neutron yield distributions from #alpha#-particle induced reactions on thick targets are made with measured data to analyze the initial reaction process in the framework of the exciton (hybrid) model code ALICE91 (M. Blann, Lawrence Livermore National Laboratory Report UCID 19614, 1982). We have considered two reaction mechanisms: dissolution of the #alpha# in the nuclear field, and preequilibrium processes initiated by #alpha#-nucleon collisions. Both these processes seem to contribute to the emitted neutron spectra in varying proportions depending on the incident #alpha# energy and possibly on the target nucleus. Contributions from other processes appear to be non-negligible.

2003-06-01

329

A combined numerical and theoretical study on the penetration of a jacketed rod into semi-infinite targets  

British Library Electronic Table of Contents (United Kingdom)

A combined numerical and theoretical study is conducted herein on the penetration of semi-infinite targets by jacketed rods with different r"j"0/r"c"0 ratios where r"j"0 and r"c"0 are the radii of the jacket and the core, respectively. The numerical results show that for smaller r"j"0/r"c"0 ratios the u-v relationship changes only a little compared to that of unitary long rod penetrator of the same core material, hence, the u-v relationship of unitary (homogeneous) long rod penetration is also applicable for jacketed rod penetration. Model for cratering in semi-infinite targets by jacketed rods is then suggested by using the laws of conversation of mass, momentum and energy, together with the u-v relationship of unitary (homogeneous) long rod penetration and an analytical model for predict...

2011-01-01

330

Variable domain I of nematode CLEs directs post-translational targeting of CLE peptides to the extracellular space  

UK PubMed Central (United Kingdom)

Effector proteins expressed in the esophageal gland cells of cyst nematodes are delivered into plant cells through a hollow, protrusible stylet. Although evidence indicates that effector proteins function...Full Text Available

2010-12-01

331

Update on the Role of Substantia Nigra Pars Reticulata in the Regulation of Seizures  

UK PubMed Central (United Kingdom)

The substantia nigra pars reticulata (SNR) represents an endogenous seizure suppressing system, which may be targeted to develop treatments for generalized or multifocal epilepsies. This review summarizes...Full Text Available

2006-05-01

332

Three-dimensional simulation study of compact toroid plasmoid injection into magnetized plasmas  

Energy Technology Data Exchange (ETDEWEB)

Three-dimensional dynamics of a compact toroid (CT) plasmoid, which is injected into a magnetized target plasma region is investigated by using magnetohydrodynamic (MHD) numerical simulations. It is found that the process of the CT penetration into this region is much more complicated than what has been analyzed so far by using a conducting sphere (CS) model. The injected CT suffers from a tilting instability, which grows with the similar time scale as the CT penetration. The instability is accompanied by magnetic reconnection between the CT magnetic field and the target magnetic field, which disrupts the magnetic configuration of the CT. Magnetic reconnection plays a role to supply the high density plasma initially confined in the CT magnetic field into the target region. Also, the penetration depth of the CT high density plasma is examined. It is shown to be shorter than that estimated from the CS model. The CT high ...

1999-04-01

333

The sensitivity of real-time PCR amplification targeting invasive Salmonella serovars in biological specimens  

UK PubMed Central (United Kingdom)

BackgroundPCR amplification for the detection of pathogens in biological material is generally considered a rapid and informative diagnostic technique. Invasive Salmonella...Full Text Available

334

The selective hypoxia inducible factor-1 inhibitor PX-478 provides in vivo radiosensitization through tumor stromal effects  

UK PubMed Central (United Kingdom)

Hypoxia inducible factor-1 (HIF-1) promotes tumor cell adaptation to microenvironmental stress. HIF-1 is up-regulated in irradiated tumors and serves as a promising target for radiosensitization....Full Text Available

2009-04-01

335

The selection and definition of targeted work-related conditions for surveillance under SENSOR.  

UK PubMed Central (United Kingdom)

Lists of reportable conditions and case definitions are important tools for epidemiologic surveillance. As part of an initiative to encourage occupational disease surveillance systems linked to intervention...Full Text Available

1989-12-01

336

The prospects for polarized target materials with pure carbon background  

Science.gov (United States)

None of the materials presently in common use for polarized proton targets has a pure carbon nuclear background. The alcohols and diols contain some oxygen, and the ammonia and amine-based materials contain nitrogen and/or other noncarbon species. In the latter cases the noncarbon nuclei are measurably polarized as a concomitant of the process used to polarize the hydrogen nuclei. The relative simplicity of a pure carbon background would be advantageous for most types of scattering experiments and perhaps crucial for some. In addition to simplifying the kinematics of background events, pure carbon is relatively easy to prepare as a dummy'' target for background subtraction. Also, in such a target material, [sup 13]C-enrichment would yield a clean polarized [sup 13]C material. In this note I explore the possibilities for such materials, touching upon only what I consider to be the ...

1992-10-06

337

The implication of Sir2 in replicative aging and senescence in Saccharomyces cerevisiae  

UK PubMed Central (United Kingdom)

The target of rapamycin (TOR) pathway regulates cell growth and aging in various organisms. In Saccharomyces cerevisiae, silent information regulator 2 (Sir2) modulates cellular senescence. Moreover,...Full Text Available

338

The anxious wait: assessing the impact of patient accessible EHRs for breast cancer patients  

UK PubMed Central (United Kingdom)

BackgroundPersonal health records (PHRs) provide patients with access to personal health information (PHI) and targeted education. The use of PHRs has the potential to improve a...Full Text Available

339

The Spectrum of Monogenic Autoinflammatory Syndromes: Understanding Disease Mechanisms and Use of Targeted Therapies  

UK PubMed Central (United Kingdom)

Monogenic autoinflammatory diseases encompass a distinct and growing clinical entity of multisystem inflammatory diseases with known genetic defects in the innate immune system. The diseases...Full Text Available

2008-07-01

340

The Regulation of Aging and Longevity  

UK PubMed Central (United Kingdom)

p53 plays a critical role in tumor suppression. As a transcription factor, in response to stress signals, p53 regulates its target genes and initiates stress responses, including cell cycle arrest,...Full Text Available

2011-04-01

341

The Magdalena Ridge Observatory 2.4 m Telescope  

Science.gov (United States)

EOS Technologies has been commissioned to design and build a unique 2.4m astronomical telescope for the Magdalena Ridge Observatory. This telescope utilizes a high quality primary mirror and cell from a now decommissioned military application. This paper describes the project and gives an overview of the telescope design. The Magdalena Ridge Observatory (MRO) 2.4 meter telescope will be primarily utilized to observe, track, and characterize solar system astronomical targets, Earth satellites, space vehicles, and terrestrial military targets. The telescope's rapid tracking (slew rates are 10o/sec) will allow it to move to any target and acquire data within one minute of receipt of notice. In this way, the telescope will be used to capitalize on targets of opportunity that occur in asteroid studies (e.g., Near Earth Objects) and in astrophysics, such as gamma ray bursts and other transient phenomena. ...

2006-07-01

342

The Burden of Common Infectious Disease Syndromes at the Clinic and Household Level from Population-Based Surveillance in Rural and Urban Kenya  

UK PubMed Central (United Kingdom)

BackgroundCharacterizing infectious disease burden in Africa is important for prioritizing and targeting limited resources for curative and preventive services and monitoring the...Full Text Available

343

Targeting the p53 Pathway in Ewing Sarcoma  

UK PubMed Central (United Kingdom)

The p53 tumour suppressor plays a pivotal role in the prevention of oncogenic transformation. Cancers frequently evade the potent antitumour surveillance mechanisms of p53 through mutation of the TP53...Full Text Available

2011-01-01

344

Targeting the Pentose Phosphate Pathway in Syndrome X-related Cardiovascular Complications  

UK PubMed Central (United Kingdom)

Syndrome X is a combination or co-occurrence of several known cardiovascular risk factors (including central obesity, dyslipidemias, fatty liver disease, hyperinsulinemia, insulin resistance,...Full Text Available

2010-05-01

345

Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase  

UK PubMed Central (United Kingdom)

The development of new methods for gene addition to mammalian genomes is necessary to overcome the limitations of conventional genetic engineering strategies. Although a variety of DNA-modifying enzymes...Full Text Available

2011-09-01

346

Targeted gene transfection from microbubbles into vascular smooth muscle cells using focused, ultrasound-mediated delivery  

UK PubMed Central (United Kingdom)

We investigate a method for gene delivery to vascular smooth muscle cells using ultrasound triggered delivery of plasmid DNA from electrostatically coupled cationic microbubbles. Microbubbles...Full Text Available

2010-09-01

347

Target organs and systems: methodologies to assess immune system function.  

UK PubMed Central (United Kingdom)

Immunotoxicity encompasses both reduced and heightened immune function. Diverse chemicals can impair functioning of the immune system. Both monographs and books have been devoted to detailed descriptions...Full Text Available

1998-04-01

348

Systematics of average radiative width of heavy nuclides  

Energy Technology Data Exchange (ETDEWEB)

Systematics of neutron capture radiative width were studied in the target element range from Th to Cm. Reduced radiative widths were analyzed with a simple radiative width formula based on E1 transition. Average radiative width is presented with the standard deviation of 15%. (author)

1999-03-01

349

Synthetic substrates for measuring activity of autophagy proteases  

UK PubMed Central (United Kingdom)

Atg4 cysteine proteases (autophagins) play crucial roles in autophagy by proteolytic activation of Atg8 paralogs for targeting to autophagic vesicles by lipid conjugation, as well as in subsequent deconjugation...Full Text Available

2010-10-01

350

Synthesis and characterization of a biotinylated organophosphorus ester for detection and affinity purification of a brain serine esterase: neuropathy target esterase.  

UK PubMed Central (United Kingdom)

We have synthesized a novel stable precursor, saligenin phosphorotrichloridate, which, on reaction with N-monobiotinyldiamines, generates a series of biotinylated covalent inhibitors of serine esterases....Full Text Available

1994-07-15

351

Structure of Natural Killer Cell Receptor KLRG1 Bound to E-Cadherin Reveals Basis for MHC-Independent Missing Self Recognition  

UK PubMed Central (United Kingdom)

SUMMARYThe cytolytic activity of natural killer (NK) cells is regulated by inhibitory receptors that detect the absence of self molecules on target cells. Structural studies of...Full Text Available

2009-07-17

352

Stem cell niches and other factors that influence the sensitivity of bone marrow to radiation-induced bone cancer and leukaemia in children and adults  

UK PubMed Central (United Kingdom)

Purpose: This paper reviews and reassesses the internationally accepted niches or ‘targets’ in bone marrow that are sensitive to the induction of leukaemia and primary...Full Text Available

2011-04-01

353

Species-specific microRNA roles elucidated following astrocyte activation  

UK PubMed Central (United Kingdom)

MicroRNAs (miRNAs) are short non-coding RNAs that play a central role in regulation of gene expression by binding to target genes. Many miRNAs were associated with the function of the central nervous...Full Text Available

2011-05-01

354

Soluble Epoxide Hydrolase as a Therapeutic Target for Cardiovascular Diseases  

UK PubMed Central (United Kingdom)

PrefaceCardiovascular effects of epoxyeicosatrienoic acids (EETs) include vasodilation, vascular smooth muscle cell anti-migratory actions, and anti-inflammatory actions. These...Full Text Available

2009-10-01

355

Soluble Epoxide Hydrolase Inhibition: Targeting Multiple Mechanisms of Ischemic Brain Injury with a Single Agent  

UK PubMed Central (United Kingdom)

SummarySoluble epoxide hydrolase (sEH) is a key enzyme in the metabolic conversion and degradation of P450 eicosanoids called epoxyeicosatrienoic acids (EETs). Genetic variations...Full Text Available

2009-03-01

356

Roles of lead-binding proteins in mediating lead bioavailability.  

UK PubMed Central (United Kingdom)

The intracellular bioavailability of lead (Pb) at low dosage levels in major target organs such as the kidney and brain appears to be largely determined by complexation with a group of low molecular...Full Text Available

1998-12-01

357

Role of nitroso radicals as drug targets in circulatory shock  

UK PubMed Central (United Kingdom)

A vast amount of circumstantial evidence implicates oxygen-derived free radicals (especially, superoxide and hydroxyl radical) and high-energy oxidants [such as peroxynitrite (OONO)]...Full Text Available

2009-06-01

358

Regional Convection-Enhanced Delivery of Gadolinium-labeled Albumin in the Rat Hippocampus In Vivo  

UK PubMed Central (United Kingdom)

Convection-enhanced delivery (CED) has emerged as a promising method of targeted drug-delivery for treating central nervous system (CNS) disorders, but the influence of brain structure on infusate...Full Text Available

2010-03-15

359

Rare Homologous Gene Targeting in Histoplasma capsulatum: Disruption of the URA5Hc Gene by Allelic Replacement  

UK PubMed Central (United Kingdom)

URA5 genes encode orotidine-5′-monophosphate pyrophosphorylase (OMPpase), an enzyme involved in pyrimidine biosynthesis. We cloned the Histoplasma capsulatum URA5...Full Text Available

1998-10-01

360

Rapid, sensitive detection of Mycoplasma pneumoniae in simulated clinical specimens by DNA amplification.  

UK PubMed Central (United Kingdom)

The polymerase chain reaction (PCR) was investigated as a means of diagnosing Mycoplasma pneumoniae infections. The target DNA sequence was a 375-bp segment of the P1 virulence protein. This DNA segment...Full Text Available

1992-12-01

361

Rapamycin inhibits trypanosome cell growth by preventing TOR complex 2 formation  

UK PubMed Central (United Kingdom)

Target of rapamycin (TOR) kinases control cell growth through two functionally distinct multiprotein complexes. TOR complex 1 (TORC1) controls temporal cell growth and is sensitive to rapamycin, whereas...Full Text Available

2008-09-23

362

ROCK DEFORMATION. Final Progress Report  

Energy Technology Data Exchange (ETDEWEB)

The Gordon Research Conference (GRC) on ROCK DEFORMATION was held at II Ciocco from 5/19/02 thru 5/24/02. Emphasis was placed on current unpublished research and discussion of the future target areas in this field.

2002-05-24

363

RNA:DNA Ratio and Other Nucleic Acid Derived Indices in Marine Ecology  

UK PubMed Central (United Kingdom)

Some of most used indicators in marine ecology are nucleic acid-derived indices. They can be divided by target levels in three groups: 1) at the organism level as ecophysiologic indicators, indicators...Full Text Available

364

Putative Biomarkers and Targets of Estrogen Receptor Negative Human Breast Cancer  

UK PubMed Central (United Kingdom)

Breast cancer is a progressive and potentially fatal disease that affects women of all ages. Like all progressive diseases, early and reliable diagnosis is the key for successful treatment and annihilation....Full Text Available

365

Protein Targets of Reactive Metabolites of Thiobenzamide in Rat Liver In Vivo  

UK PubMed Central (United Kingdom)

Thiobenzamide (TB) is a potent hepatotoxin in rats, causing dose-dependent hyperbilirubinemia, steatosis, and centrolobular necrosis. These effects arise subsequent to and appear to result from...Full Text Available

2008-07-01

366

Protein Damage by Reactive Electrophiles: Targets and Consequences  

UK PubMed Central (United Kingdom)

It has been sixty years since the Millers first described the covalent binding of carcinogens to tissue proteins. Protein covalent binding was gradually overshadowed by the emergence of DNA...Full Text Available

2008-01-01

367

Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation  

UK PubMed Central (United Kingdom)

The parathyroid hormone receptor (PTHR) is a class B G protein-coupled receptor that plays critical roles in bone and mineral ion metabolism. Ligand binding to the PTHR involves interactions to both...Full Text Available

2008-10-28

368

Preparation of a "6"2Zn-"6"2Cu generator and of "6"1Cu following alpha particle irradiation of a nickel target  

International Nuclear Information System (INIS)

The "6"2Zn-"6"2Cu generator system is one of the few which yield a pure positron emitting daughter. The authors have developed a method for the preparation of this generator system following 32 MeV #alpha# particle bombardment of nickel targets. The chemical processing involves two stages: first a hydrous zirconium oxide column is used at pH 4-5 to separate the zinc and copper activities produced in the target nickel, and secondly, a conventional anion exchange column is used to retain the "6"2Zn and remove all copper activities in 2M HCl. This column serves as the "6"2Cu generator which will yield pure "6"2Cu repeatedly, free from "6"2Zn and other impurities, in a mixture of HCl and NaCl. A method is outlined also to obtain a solution of "6"2Zn using the hydrous zirconium oxide (HZO) column. "6"1Cu can be prepared as a by-product in the above procedure, but a method for the preparation of "6"1Cu alone using an 18 MeV #alpha# particle beam on a ...

369

Predictive and prognostic markers for epidermal growth factor receptor inhibitor therapy in non-small cell lung cancer  

UK PubMed Central (United Kingdom)

Epidermal growth factor receptor (EGFR) related therapies – mainly tyrosine kinase inhibitors (TKIs) such as erlotinib and gefitinib, but also monoclonal antibodies targeting EGFR, for example,...Full Text Available

2009-11-01

370

Potential of mTOR inhibitors for the treatment of subependymal giant cell astrocytomas in tuberous sclerosis complex  

UK PubMed Central (United Kingdom)

Rapamycin inhibits the mTOR (target of rapamycin) pathway and extends lifespan in multiple species. The tuberous sclerosis complex (TSC) protein is a negative regulator of mTOR. In humans, loss of the...Full Text Available

371

Potassium channels as a potential therapeutic target for trigeminal neuropathic and inflammatory pain  

UK PubMed Central (United Kingdom)

Previous studies in several different trigeminal nerve injury/inflammation models indicated that the hyperexcitability of primary afferent neurons contributes to the pain pathway underlying mechanical...Full Text Available

372

Pion-induced fission  

Energy Technology Data Exchange (ETDEWEB)

The A(..pi../sup +/,/sup 3/He)B reaction near threshold is studied in a model where the pion is absorbed by an /sup 4/He constituent of the target nucleus. The predictions of this model using harmonic oscillator cluster wave functions agree semi-quantitatively with the experimental data on the inverse reaction.

1982-03-10

373

Paradoxical function for the receptor for advanced glycation end products in mouse models of pulmonary fibrosis  

UK PubMed Central (United Kingdom)

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with poor survival. The identification of therapeutic targets is essential to improving outcomes. Previous studies found that expression...Full Text Available

2011-03-31

374

Pancreatic cancer: molecular pathogenesis and new therapeutic targets  

UK PubMed Central (United Kingdom)

Patients with pancreatic cancer normally present with advanced disease that is lethal and notoriously difficult to treat. Survival has not improved dramatically, despite routine use of chemotherapy...Full Text Available

2009-07-01

375

PCR-based method for targeting 16S-23S rRNA intergenic spacer regions among Vibrio species  

UK PubMed Central (United Kingdom)

BackgroundThe genus Vibrio is a diverse group of Gram-negative bacteria comprised of 74 species. Furthermore, the genus has and is expected to continue expanding...Full Text Available

376

Optimization of isotope production by cross section determination  

International Nuclear Information System (INIS)

In order to optimize the production of "2"0"1Tl and "6"7Ga using the (p, xn) reactions on enriched "2"0"3Tl and "6"8Zn targets we established a new set of cross section curves for the most relevant reactions. Target stacks made of up to 15 thin (50 #mu#m) natural Tl or Zn foils interleaved with brass degradation foils were irradiated with incident proton energies from 42 to 10 MeV in overlapping experiments. Yields for "2"0"0","2"0"1","2"0"2"m","2"0"3","2"0"4"mPB and "6"6","6"7","6"8Ga were computed from measured #gamma# emission rates. Where possible, cross section curves for the nuclear reactions involved were computed. Thick target yields and contamination ratios for enriched targets were derived and show good agreement with results from actual production runs. (orig.).

377

Optimal bone strength and mineralization requires the type 2 iodothyronine deiodinase in osteoblasts  

UK PubMed Central (United Kingdom)

Hypothyroidism and thyrotoxicosis are each associated with an increased risk of fracture. Although thyroxine (T4) is the predominant circulating thyroid hormone, target cell responses are determined...Full Text Available

2010-04-20

378

Nucleoside Drugs Induce Cellular Differentiation by Caspase-Dependent Degradation of Stem Cell Factors  

UK PubMed Central (United Kingdom)

BackgroundStem cell characteristics are an important feature of human cancer cells and play a major role in the therapy resistance of tumours. Strategies to target cancer stem cells...Full Text Available

379

Nuclear Targeting of Methyl-Recycling Enzymes in Arabidopsis thaliana Is Mediated by Specific Protein Interactions.  

Science.gov (United States)

Numerous transmethylation reactions are required for normal plant growth and development. S-adenosylhomocysteine hydrolase (SAHH) and adenosine kinase (ADK) act coordinately to recycle the by-product of these reactions, S-adenosylhomocysteine (SAH) that would otherwise competitively inhibit methyltransferase (MT) activities. Here, we report on investigations to understand how the SAH produced in the nucleus is metabolized by SAHH and ADK. Localization analyses using green fluorescent fusion proteins demonstrated that both enzymes are capable of localizing to the cytoplasm and the nucleus, although no obvious nuclear localization signal was found in their sequences. Deletion analysis revealed that a 41-amino-acid segment of SAHH (Gly(150)-Lys(190)) is required for nuclear targeting of this enzyme. This segment is surface exposed, shows unique sequence conservation patterns in plant SAHHs, and possesses additional features of protein-protein interaction motifs. ADK ...

2011-10-01

380

Noradrenergic ?1 Receptors as a Novel Target for the Treatment of Nicotine Addiction  

UK PubMed Central (United Kingdom)

Nicotine is the main psychoactive ingredient in tobacco and its rewarding effects are considered primarily responsible for persistent tobacco smoking and relapse. Although dopamine has been extensively...Full Text Available

2010-07-01

381

Nano to micro delivery systems: targeting angiogenesis in brain tumors  

UK PubMed Central (United Kingdom)

Treating brain tumors using inhibitors of angiogenesis is extensively researched and tested in clinical trials. Although anti-angiogenic treatment holds a great potential for treating primary and secondary...Full Text Available

382

Multiple Functions of the 37/67-kd Laminin Receptor Make It a Suitable Target for Novel Cancer Gene Therapy  

UK PubMed Central (United Kingdom)

The 37/67-kd laminin receptor, LAMR, is a multifunctional protein that associates with the 40S ribosomal subunit and also localizes to the cell membrane to interact with the extracellular matrix. LAMR...Full Text Available

2010-01-01

383

Motion compensation with a scanned ion beam: a technical feasibility study  

UK PubMed Central (United Kingdom)

BackgroundIntrafractional motion results in local over- and under-dosage in particle therapy with a scanned beam. Scanned beam delivery offers the possibility to compensate target...Full Text Available

384

Molecular dynamics of a ?B DNA element: base flipping via cross-strand intercalative stacking in a microsecond-scale simulation  

UK PubMed Central (United Kingdom)

The sequence-dependent structural variability and conformational dynamics of DNA play pivotal roles in many biological milieus, such as in the site-specific binding of transcription factors to target...Full Text Available

2008-09-01

385

MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms  

UK PubMed Central (United Kingdom)

MicroRNAs (miRNAs) are endogenously encoded small noncoding RNAs, derived by processing of short RNA hairpins, that can inhibit the translation of mRNAs bearing partially complementary target sequences....Full Text Available

2003-08-19

386

Mechanisms of confluence-dependent expression of CD26 in colon cancer cell lines  

UK PubMed Central (United Kingdom)

BackgroundCD26 (dipeptidyl peptidase IV, DPPIV) is a 110 kDa surface glycoprotein expressed in most normal tissues, and is a potential novel therapeutic target for selected cancers....Full Text Available

387

Measurements of Spectral Characteristics of Swimmer Targets ...  

Science.gov (United States)

... 3.0 Radar Measurements 3-1 3. 1 Spectral Density Measurements 3-2 3. 1. 1 System Calibration 3-3 ... 3. 1 SPECTRAL DENSITY MEASUREMENTS ...

1974-05-01

388

Materials considerations for the National Spallation Neutron Source target  

Energy Technology Data Exchange (ETDEWEB)

The National Spallation Neutron Source (NSNS), in which neutrons are generated by bombarding a liquid mercury target with 1 GeV protons, will place extraordinary demands on materials performance. The target structural material will operate in an aggressive environment, subject to intense fluxes of high energy protons, neutrons, and other particles, while exposed to liquid mercury and to water. Components that require special consideration include the Hg liquid target container and protective shroud, beam windows, support structures, moderator containers, and beam tubes. In response to these demands a materials R and D program has been developed for the NSNS that includes: selection of materials; calculations of radiation damage; irradiations, post irradiation testing, and characterization; compatibility testing and characterization; design and implementation of a plan for monitoring of materials performance in service; and ...

1997-08-01

389

Mass Production of 64Cu with 64Ni(p,n)64Cu Nuclear Reaction and Target Material Recycling  

International Nuclear Information System (INIS)

64Cu (T1/2=12.7h, ?- decay: 40%, ?+ decay: 19%, E.C. decay: 41%) is one of the most useful radioisotope in the nuclear medicine due to its multiple decay mode and the intermediate half-life. Several nuclear reaction, i.e., 64Ni(p,n)64Cu, 68Zn(p,?n)64Cu and 64Ni(d,2n)64Cu have been investigated for production. The highest could be obtained with proton irradiation on the enriched 64Ni target. For mass and routine production, the 64Ni target fabrication using electroplating, the reliable chemical separation of 64Cu from the irradiated 64Ni target and the effective recovery process for the recycling of very expensive enriched material ($20,000/g) and so forth are absolutely necessary to be established. In this work, we report our mass production method of 64Cu with 64Ni and Cyclone-30 accelerator

2009-05-01

390

Mammalian target of rapamycin signaling modulates photic entrainment of the suprachiasmatic circadian clock  

UK PubMed Central (United Kingdom)

Inducible gene expression appears to be an essential event that couples light to entrainment of the master mammalian circadian clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus....Full Text Available

2010-05-05

391

Linking Gene Expression and Functional Network Data in Human Heart Failure  

UK PubMed Central (United Kingdom)

BackgroundGene expression profiling and the analysis of protein-protein interaction (PPI) networks may support the identification of disease bio-markers and potential drug targets....Full Text Available

392

LYN is a mediator of epithelial-mesenchymal transition and target of dasatinib in breast cancer  

UK PubMed Central (United Kingdom)

Epithelial-mesenchymal transition (EMT), a switch of polarized epithelial cells to a migratory, fibroblastoid phenotype, is considered a key process driving tumor cell invasiveness and metastasis....Full Text Available

2010-03-15

393

Kinetic Complexity of the Global Response to Glucocorticoid Receptor Action  

UK PubMed Central (United Kingdom)

We have characterized the kinetic response of gene targets throughout the murine genome to transcriptional modulation by the glucocorticoid receptor (GR). In contrast to a model in which multiple genes...Full Text Available

2009-04-01

394

Key Beliefs for Targeted Interventions to Increase Physical Activity in Children: Analyzing Data from an Extended Version of the Theory of Planned Behaviour  

UK PubMed Central (United Kingdom)

Given the high prevalence of overweight and low levels of physical activity among children, a better understanding of physical activity behaviour is an important step in intervention planning. This...Full Text Available

2010-01-01

395

Intracellular delivery of an antisense?oligonucleotide via endocytosis of a G protein-coupled receptor  

UK PubMed Central (United Kingdom)

Gastrin-releasing peptide receptor (GRPR), a member of the G protein-coupled receptor superfamily, has been utilized for receptor-mediated targeting of imaging and therapeutic agents; here we extend...Full Text Available

2010-10-01

396

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression  

UK PubMed Central (United Kingdom)

As the result of genetic alterations and tumor hypoxia, many cancer cells avidly take up glucose and generate lactate through lactate dehydrogenase A (LDHA), which is encoded by a target gene of c-Myc...Full Text Available

2010-02-02

397

Increased degradation of MYPT1 contributes to the development of tolerance to nitric oxide in porcine pulmonary artery  

UK PubMed Central (United Kingdom)

Myosin phosphatase target subunit 1 (MYPT1) is the regulatory subunit of myosin light chain phosphatase (MLCP). It plays a critical role in vasodilatation induced by cGMP-elevating agents such as nitric...Full Text Available

2010-07-01

398

In vivo expression and mitochondrial targeting of yeast apoiso-1-cytochrome c fusion proteins.  

UK PubMed Central (United Kingdom)

To define the import pathway for apoiso-1-cytochrome c in vivo, the coding region for bacterial chloramphenicol acetyltransferase (CAT) or yeast copper metallothionein (CuMT) was fused to the carboxy...Full Text Available

1990-11-01

399

In vitro analysis of nuclear mRNA export using molecular beacons for target detection  

UK PubMed Central (United Kingdom)

A detailed molecular characterization of nuclear mRNA export will require an in vitro system, allowing a biochemical reconstitution of transport. To this end, an mRNA export assay has...Full Text Available

2003-06-01

400

Immunochemical Analysis of the Temporal and Tissue-Specific Expression of an Avena sativa Plasma Membrane Determinant 1  

UK PubMed Central (United Kingdom)

An immunoglobulin Mk monoclonal (F8IVE9) antibody raised against oat (Avena sativa cv Garry) root homogenate has been produced and characterized. The predominant target...Full Text Available

1992-01-01

401

Identification of circulating neuropilin-1 and dose-dependent elevation following anti-neuropilin-1 antibody administration  

UK PubMed Central (United Kingdom)

Neuropilin-1 (NRP1) acts as a co-receptor for class 3 semaphorins and vascular endothelial growth factor and is an attractive angiogenesis target for cancer therapy. In addition to the transmembrane...Full Text Available

2009-07-01

402

Identification of Achaete-scute complex-like 1 (ASCL1) target genes and evaluation of DKK1 and TPH1 expression in pancreatic endocrine tumours  

UK PubMed Central (United Kingdom)

BackgroundASCL1 role in pancreatic endocrine tumourigenesis has not been established. Recently it was suggested that ASCL1 negatively controls expression of the...Full Text Available

403

Identification and Characterization of Retinoid-Active Short-Chain Dehydrogenases/Reductases in Drosophila melanogaster  

UK PubMed Central (United Kingdom)

BackgroundIn chordates, retinoid metabolism is an important target of short-chain dehydrogenases/reductases (SDRs). It is not known whether SDRs play a role in retinoid...Full Text Available

2009-10-01

404

INVERTEBRATE FAUNA ASSOCIATED WITH TORPEDOGRASS, PANICUM REPENS (CYPERALES: POACEAE), IN LAKE OKEECHOBEE, FLORIDA, AND ...  

Science.gov (United States)

... 154. By way of comparison, the aquatic weed Hygrophila polysperma (Roxb.) T. Anderson, a potential target for biological ... L. Sutton. 2000. Is the aquatic weed hygrophila, Hygrophila polysperma (Polemon...

405

Human Immunodeficiency Virus-1 Inhibition of Immunoamphisomes in Dendritic Cells Impairs Early Innate and Adaptive Immune Responses  

UK PubMed Central (United Kingdom)

SUMMARYDendritic cells (DCs) in mucosal surfaces are early targets for human immunodeficiency virus-1 (HIV-1). DCs mount rapid and robust immune responses upon pathogen encounter....Full Text Available

2010-05-28

406

Heat Stress Enhances the Accumulation of Polyadenylated Mitochondrial Transcripts in Arabidopsis thaliana  

UK PubMed Central (United Kingdom)

BackgroundPolyadenylation of RNA has a decisive influence on RNA stability. Depending on the organisms or subcellular compartment, it either enhances transcript stability or targets...Full Text Available

407

Health and function of participants in the Long Life Family Study: A comparison with other cohorts  

UK PubMed Central (United Kingdom)

Individuals from families recruited for the Long Life Family Study (LLFS) (n= 4559) were examined and compared to individuals from other cohorts to determine whether the recruitment targeting longevity...Full Text Available

408

Hair Mercury Negatively Correlates with Calcium Pump Activity in Human Term Newborns and Their Mothers at Delivery  

UK PubMed Central (United Kingdom)

BackgroundCalcium homeostasis is a known target of several environmental toxicants including lead and mercury.ObjectiveOur goal was to determine...Full Text Available

2008-02-01

409

Gyrase B Inhibitor Impairs HIV-1 Replication by Targeting Hsp90 and the Capsid Protein*  

UK PubMed Central (United Kingdom)

Chemical genetics is an emerging approach to investigate the biology of host-pathogen interactions. We screened several inhibitors of ATP-dependent DNA motors and detected the gyrase B inhibitor coumermycin...Full Text Available

2010-12-10

410

Goldin says NASA must reach streamlining targets - Johnson Space ...  

Science.gov (United States)

Jan 20, 1995 ... Jenn-Air dowedraft cooktop, staintess steel, coil. $75; telephone ans mach, $25. Eric, x31917. $295; President & First Lady premier plus ...

411

Glutamatergic regulation of ghrelin-induced activation of the mesolimbic dopamine system  

UK PubMed Central (United Kingdom)

Recently, we demonstrated that the central ghrelin signalling system, involving the ghrelin receptor (GHS-R1A), is important for alcohol reinforcement. Ghrelin targets a key mesolimbic circuit involved...Full Text Available

2011-01-01

412

Genetic Diversity in Blastomyces dermatitidis: Implications for PCR Detection in Clinical and Environmental Samples  

UK PubMed Central (United Kingdom)

SummaryBlastomycosis is a serious and potentially fatal infection by the thermally dimorphic fungus Blastomyces dermatitidis. PCR assays targeting the BAD-1 virulence...Full Text Available

2010-03-01

413

Gene expression analysis of interferon ? in laser capture microdissected cervical epithelium  

UK PubMed Central (United Kingdom)

Optimal sample handling techniques for tissue preparation and storage, RNA extraction and quantification, and target gene detection are crucial for reliable gene expression analysis. Methods...Full Text Available

2008-10-01

414

Fyn Is a Novel Target of (?)-Epigallocatechin Gallate in the Inhibition of JB6 Cl41 Cell Transformation  

UK PubMed Central (United Kingdom)

The cancer preventive action of (−)-epigallocatechin gallate (EGCG), found in green tea, is strongly supported by epidemiology and laboratory research data. However, the mechanism by...Full Text Available

2008-03-01

415

Forecasting changes in amphibian biodiversity: aiming at a moving target  

UK PubMed Central (United Kingdom)

Amphibian population declines and sudden species' extinctions began to be noted at the beginning of the 1980s. Understanding the causes of the losses is hampered by our poor knowledge of the amphibian...Full Text Available

2005-02-28

416

Food Advertising and Marketing Directed at Children and Adolescents in the US  

UK PubMed Central (United Kingdom)

In recent years, the food and beverage industry in the US has viewed children and adolescents as a major market force. As a result, children and adolescents are now the target of intense and specialized...Full Text Available

417

First line targeted therapies in breast cancer: focus on bevacizumab  

UK PubMed Central (United Kingdom)

The heterogeneity of metastatic breast cancer mandates the need to select therapies taking into account tumor and patient characteristics. Chemotherapy is indicated in the palliative setting especially...Full Text Available

2007-03-01

418

Excitation functions for proton-induced reactions on natural hafnium: Production of {sup 177}Lu for medical use  

Energy Technology Data Exchange (ETDEWEB)

There is an increasing interest in using radioisotopes of rare earth elements for internal radiotherapy and for imaging in nuclear medicine. {sup 177}Lu is one of the promising radionuclides. This article reports on the first measurements of the excitation function for the production of {sup 177}Lu with proton-beam energies up to 17 MeV on natural hafnium targets. The experimental cross sections for the reaction {sup nat}Hf(p,x){sup 177}Lu were obtained by the activation of a stacked-foil target and subsequent gamma spectrometry. Theoretical cross sections were calculated up to 35 MeV with the EMPIRE nuclear reaction model code. The measured and calculated cross sections were used for deriving the thick-target yields and for estimating the production of other nuclides than {sup 177}Lu. Measured production cross sections of {sup 175,176,177,178}Ta on the same target are also presented.

2009-11-15

419

Excitation functions for proton-induced reactions on natural hafnium: Production of "1"7"7Lu for medical use  

International Nuclear Information System (INIS)

There is an increasing interest in using radioisotopes of rare earth elements for internal radiotherapy and for imaging in nuclear medicine. "1"7"7Lu is one of the promising radionuclides. This article reports on the first measurements of the excitation function for the production of "1"7"7Lu with proton-beam energies up to 17 MeV on natural hafnium targets. The experimental cross sections for the reaction "n"a"tHf(p,x)"1"7"7Lu were obtained by the activation of a stacked-foil target and subsequent gamma spectrometry. Theoretical cross sections were calculated up to 35 MeV with the EMPIRE nuclear reaction model code. The measured and calculated cross sections were used for deriving the thick-target yields and for estimating the production of other nuclides than "1"7"7Lu. Measured production cross sections of "1"7"5","1"7"6","1"7"7","1"7"8Ta on the same target are also presented.

2009-11-01

420

Examining the Phonological Neighborhood Density Effect Using Near Infrared Spectroscopy  

UK PubMed Central (United Kingdom)

Phonological density refers to the number of words that can be generated by replacing a phoneme in a target word with another phoneme in the same position. Although the precise nature of the...Full Text Available

2011-09-01

421

Evidence for divided automatic attention  

Scientific Electronic Library Online (English)

Abstract in english A long-standing debate in the literature is whether attention can form two or more independent spatial foci in addition to the well-known unique spatial focus. There is evidence that voluntary visual attention divides in space. The possibility that this also occurs for automatic visual attention was investigated here. Thirty-six female volunteers were tested. In each trial, a prime stimulus was presented in the left or right visual hemifield. This stimulus was characteriz (more) ed by the blinking of a superior, middle or inferior ring, the blinking of all these rings, or the blinking of the superior and inferior rings. A target stimulus to which the volunteer should respond with the same side hand or a target stimulus to which she should not respond was presented 100 ms later in a primed location, a location between two primed locations or a location in the contralateral hemifield. Reaction time to the positive ...

2008-02-01

422

Evidence for an association between TSH and IGF-1 receptors  

UK PubMed Central (United Kingdom)

TSH receptor (TSHR) plays a central role in regulating thyroid function and is targeted by IgGs in Graves’ disease (GD-IgG). Whether TSHR is involved in the pathogenesis of thyroid associated...Full Text Available

2008-09-15

423

Evaluation of heterogeneity effects for Am reaction rates of the moderated subassemblies  

Energy Technology Data Exchange (ETDEWEB)

The technology of minor actinide recycling in fast reactors has been discussed. In CEA, the feasibility study on Am once-through recycling in Phenix core with the moderated target subassemblies (S/As) has been performed. In this report, the evaluation of the heterogeneity effect on the moderated target S/As is described. It was evaluated by the calculation with the continuous energy Monte-Carlo code, MVP, because the accuracy of the deterministic method for the moderated target S/As is unknown. The reaction rates of four isotopes (Am-241, Am-242, Am242m and Am-243) calculated with the heterogeneous model and the homogeneous one were compared. These four isotopes play the important role in Am incineration. It is seen that the homogeneous model overestimates the reaction rates of Am-241 and Am-243 by 4 - 13%, and underestimates those of Am-242 and Am-242m by 13 - 23%. Further investigation made it clear that the ...

1998-10-01

424

Emulsified Nanoparticles Containing Inactivated Influenza Virus and CpG Oligodeoxynucleotides Critically Influences the Host Immune Responses in Mice  

UK PubMed Central (United Kingdom)

BackgroundAntigen sparing and cross-protective immunity are regarded as crucial in pandemic influenza vaccine development. Both targets can be achieved by adjuvantation strategy...Full Text Available

426

Effects of local texture and grain structure on the sputtering performance of tantalum  

Energy Technology Data Exchange (ETDEWEB)

Tantalum and tantalum-based thin films have gained precedence as the diffusion barrier for copper interconnects used in the latest generation of integrated circuits (ICs). The paper presents insight and observations on the covariance of texture and grain size of wrought tantalum sputtering targets and their influence on sputtering performance. Previous studies involving deposition trials of tantalum targets of varying metallurgical character had demonstrated that both grain size and textural homogeneity is critical for assuring reliable sputtering performance of tantalum. Subsequently, a model had been proposed to prescribe how localized texture bands and orientation clusters in tantalum are effectively resistant to sputter erosion. In this paper, results of atomic force microscopy (AFM) and orientation imaging microscopy (OIM{sup TM}) analyses on the eroded surface of a tantalum sputtering target are presented. Initial ...

2002-07-01

427

Dose Optimization for Long-term rAAV-mediated RNA Interference in the Nigrostriatal Projection Neurons  

UK PubMed Central (United Kingdom)

Short-hairpin RNA (shRNA)–mediated gene knockdown is a powerful tool for targeted gene silencing and an emerging novel therapeutic strategy. Recent publications, however, reported unexpected...Full Text Available

2009-09-01

428

Differential targeting of Tetrahymena ORC to ribosomal DNA and non-rDNA replication origins  

UK PubMed Central (United Kingdom)

The Tetrahymena thermophila origin recognition complex (ORC) contains an integral RNA subunit, 26T RNA, which confers specificity to the amplified ribosomal DNA (rDNA) origin by base...Full Text Available

2009-02-04

429

Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer  

UK PubMed Central (United Kingdom)

The p21-activated kinases (PAKs), immediate downstream effectors of the small G-proteins of the Rac/cdc42 family, are critical mediators of signaling pathways regulating cellular behaviors and...Full Text Available

2010-09-01

430

Development of fission Mo-99 production technology  

Energy Technology Data Exchange (ETDEWEB)

This R and D project is planed to supply domestic demands of Mo-99 through fission route, and consequently this project will be expected to rise up utilization of HANARO and KAERI's capability for marketing extension into domestic and oversea radiopharmaceutical market. HEU and LEU target types are decided and designed for fission Mo-99 production in domestic. Experimental study of target fabrication technology was performed and developed processing equipments. And conceptual design of target loading/unloading in/from HANARO device are performed. Tracer test of Mo-99 separation and purification process was performed, test results reach to Mo-99 recovery yield above 80% and decontamination factor above 1600. Combined Mo-99 separation and purification process was decided for hot test scheduled from next year, and performance test was performed. Conceptual design for modification of existing hot cell for fission Mo-99 ...

2001-05-01

431

Detection and Identification of Bartonella Species Pathogenic for Humans by PCR Amplification Targeting the Riboflavin Synthase Gene (ribC)  

UK PubMed Central (United Kingdom)

Several Bartonella species have now been implicated as human pathogens. The recovery of these fastidious organisms in the clinical microbiology laboratory remains difficult, and current...Full Text Available

2003-03-01

432

Dengue virus protein recognition by virus-specific murine CD8+ cytotoxic T lymphocytes.  

UK PubMed Central (United Kingdom)

The identification of the protein targets for dengue virus-specific T lymphocytes may be useful for planning the development of subunit vaccines against dengue. We studied the recognition by murine...Full Text Available

1993-02-01

433

Deformation of CHS model  

Energy Technology Data Exchange (ETDEWEB)

We calculate mass spectrum of CHS model deformed by an exactly marginal operator, and find that there are tachyons which are not localized in the target space. Similar deformation is discussed in another CFT which corresponds to separated NS5-branes. A condensation of the tachyons is briefly argued.

2002-10-07

434

DNA base mismatch detection with bulky rhodium intercalators: synthesis and applications  

UK PubMed Central (United Kingdom)

The syntheses and applications of two metallointercalators, Rh(bpy)2(chrysi)3+ and Rh(bpy)2(phzi)3+, that target single base mismatches in DNA are...Full Text Available

2007-01-01

435

Cultural Variation in Vigilance and Precaution Themes.  

Science.gov (United States)

Determine the degree to which different precautionary themes are dominant in various target populations and how these themes are acquired. Assess cultural signals of potential danger: are there different kinds of potential danger in different cultures. Do...

2009-01-01

436

Comparative Analysis of State Fish Consumption Advisories Targeting Sensitive Populations  

UK PubMed Central (United Kingdom)

ObjectiveFish consumption advisories are issued to warn the public of possible toxicological threats from consuming certain fish species. Although developing fetuses and children...Full Text Available

2008-12-01

437

Characterization of the Decision Network for Wing Expansion in Drosophila Using Targeted Expression of the TRPM8 Channel  

UK PubMed Central (United Kingdom)

After emergence, adult flies and other insects select a suitable perch and expand their wings. Wing expansion is governed by the hormone bursicon and can be delayed under adverse environmental...Full Text Available

2009-03-18

438

Characterization of Cytokinin and Adenine Transport in Arabidopsis Cell Cultures1[OA  

UK PubMed Central (United Kingdom)

Cytokinins are distributed through the vascular system and trigger responses of target cells via receptor-mediated signal transduction. Perception and transduction of the signal can occur at the plasma...Full Text Available

2008-12-01

439

Carotenoid Crystal Formation in Arabidopsis and Carrot Roots Caused by Increased Phytoene Synthase Protein Levels  

UK PubMed Central (United Kingdom)

BackgroundAs the first pathway-specific enzyme in carotenoid biosynthesis, phytoene synthase (PSY) is a prime regulatory target. This includes a number of biotechnological approaches...Full Text Available

440

CDC45 and DPB11 are required for processive DNA replication and resistance to DNA topoisomerase I-mediated DNA damage  

UK PubMed Central (United Kingdom)

The antitumor agent camptothecin targets DNA topoisomerase I by reversibly stabilizing a covalent enzyme-DNA intermediate. The subsequent collision of DNA replication forks with these drug-enzyme-DNA...Full Text Available

1999-09-28

441

Beam-forming system for electrostatic accelerator  

International Nuclear Information System (INIS)

A simple beam-forming system is described for the electrostatic accelerator of the Scientific-Research Institute of Nuclear Physics of Moscow State University. The system allows the beam to be focused on targets at various distances for a conductor potential of from 1 to 4 MV and beam currents of up to 35 #mu# A.

1988-01-01

442

Association of Unique, Isolated Treponemes with Bovine Digital Dermatitis Lesions?  

UK PubMed Central (United Kingdom)

This study used a PCR-based approach targeting 16S rRNA gene fragments to determine the occurrence and association of the three bovine digital dermatitis (BDD) treponeme phylogroups within lesions found...Full Text Available

2009-03-01

443

Analysis of target cell susceptibility as a basis for the development of a chemoprotective strategy against benzene-induced hematotoxicities.  

UK PubMed Central (United Kingdom)

A goal of our research is to identify biochemical factors that underlie the susceptibility of bone marrow cell populations to benzene metabolites so as to develop a mechanistically based chemoprotective...Full Text Available

1996-12-01

444

Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction  

UK PubMed Central (United Kingdom)

BackgroundFormation of site specific genomic double strand breaks (DSBs), induced by the expression of a pair of engineered zinc-finger nucleases (ZFNs), dramatically increases the...Full Text Available

445

An Eating Disorder Randomized Clinical Trial & Attrition: Profiles & Determinants of Dropout  

UK PubMed Central (United Kingdom)

ObjectiveThis study sought to determine whether differential treatment effects in the targeted mechanisms of change and eating disorder (ED) symptoms are associated...Full Text Available

2011-05-01

446

Alterations in the steroid hormone receptor co-chaperone FKBPL are associated with male infertility: a case-control study  

UK PubMed Central (United Kingdom)

BackgroundMale infertility is a common cause of reproductive failure in humans. In mice, targeted deletions of the genes coding for FKBP6 or FKBP52, members of the FK506 binding...Full Text Available

447

Allosteric Drug Discrimination Is Coupled to Mechanochemical Changes in the Kinesin-5 Motor Core*  

UK PubMed Central (United Kingdom)

Essential in mitosis, the human Kinesin-5 protein is a target for >80 classes of allosteric compounds that bind to a surface-exposed site formed by the L5 loop. Not established is why there...Full Text Available

2010-06-11

448

Activated PPAR? Targets Surface and Intracellular Signals That Inhibit the Proliferation of Lung Carcinoma Cells  

UK PubMed Central (United Kingdom)

Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the nuclear hormone receptor superfamily. Their discovery in the 1990s provided insights...Full Text Available

2008-01-01

449

ATG12 Conjugation to ATG3 Regulates Mitochondrial Homeostasis and Cell Death  

UK PubMed Central (United Kingdom)

SUMMARYATG12, an ubiquitin-like modifier required for macroautophagy, has a single known conjugation target, another autophagy regulator called ATG5. Here, we identify ATG3 as...Full Text Available

2010-08-20

450

A pilot application of risk-based methods to establish in-service inspection priorities for nuclear components at Surry Unit 1 Nuclear Power Station  

International Nuclear Information System (INIS)

As part of the Nondestructive Evaluation Reliability Program sponsored by the US Nuclear Regulatory Commission, the Pacific Northwest Laboratory is developing a method that uses risk-based approaches to establish in-service inspection plans for nuclear power plant components. This method uses probabilistic risk assessment (PRA) results and Failure Modes and Effects Analysis (FEMA) techniques to identify and prioritize the most risk-important systems and components for inspection. The Surry Nuclear Power Station Unit 1 was selected for pilot applications of this method. The specific systems addressed in this report are the reactor pressure vessel, the reactor coolant, the low-pressure injection, and the auxiliary feedwater. The results provide a risk-based ranking of components within these systems and relate the target risk to target failure probability values for individual components. These results will be used to guide the development of ...

451

A duplex real-time RT-PCR assay for the detection of California serogroup and Cache Valley viruses  

UK PubMed Central (United Kingdom)

A duplex TaqMan real-time RT-PCR assay was developed for the detection of California (CAL) serogroup viruses and Cache Valley virus (CVV), for use in human surveillance. The targets selected...Full Text Available

2009-10-01

452

A Vasculature-Targeting Regimen of Pre-Operative Docetaxel with or without Bevacizumab for Locally Advanced Breast Cancer  

UK PubMed Central (United Kingdom)

PurposeTaxanes have effects on angiogenesis causing difficulties in separating biologic effects of chemotherapy from those due to angiogenesis inhibitors. This randomized...Full Text Available

2009-05-15

453

A Master Conductor for Aggregate Clearance by Autophagy  

UK PubMed Central (United Kingdom)

Autophagic adapters including p62/SQSTM1 recognize polyubiquitinated autophagic targets such as toxic protein aggregates. Recently reporting in Molecular Cell, Filimonenko et al. provide evidence...Full Text Available

2010-05-18

454

A Bragg curve counter with an internal production target for the measurement of the double-differential cross-section of fragment production induced by neutrons at energies of tens of MeV  

Energy Technology Data Exchange (ETDEWEB)

A Bragg curve counter equipped with an internal production target was developed for the measurements of double-differential cross-sections of fragment production induced by neutrons at energies of tens of MeV. The internal target permitted a large detection solid angle and thus the registration of processes at low production rates. In this specific geometry, the detection solid angle depends on the emission angle and the range of the particle. Therefore the energy, atomic number, and angle of trajectory of the particle have to be taken into account for the determination of the solid angle. For the selection of events with tracks confined within a defined cylindrical volume around the detector axis, a segmented anode was applied. The double-differential cross-sections for neutron-induced production of lithium, beryllium, and boron fragments from a carbon target were measured at 0 deg. for 65 MeV neutrons. The results are in ...

2009-11-11

455

Molybdaen-targets in the Research Centre J``ulich; Erzeugung von Molybdaen fuer die Medizin im FRJ-2 des Forschungszentrums Juelich  

Energy Technology Data Exchange (ETDEWEB)

From autumn this year, the FRJ-2 of the Research Center Juelich will be supplying molybdenum targets to the Institut National des Radioelements in Fleurus, Belgium - which deals in medical radio-isotopes worldwide - thus helping to meet the need for technetium-99, which is used in the medical profession for diagnostic purposes because of its favourable radiological characteristics. Technetium-99 is formed as a result of the radioactive decay of molybdenum-99. For many years now, molybdenum has been produced by the irradiation of uranium in research reactors, so that the initiation of molybdenum production in the FRJ-2 is not especially new. What is unusual, however, are the particular peripheral conditions which result from the combination of the irradiation requirements, a predetermined target design and the technical characteristics of the reactor and which necessitated special solutions. This applies especially to the handling of the ...

1999-06-01

456

The production of carrier-free lead-203  

International Nuclear Information System (INIS)

The chemical separation of carrier-free "2"0"3Pb following deuterium bombardment of a "2"0"3Tl target is described. Coprecipitation from strontium sulphate was used to separate the "2"0"3Pb from a solution of the thallium target in sulphuric acid. The SrSO_4 precipitate was filtered, washed and dissolved in hydrochloric acid, from which "2"0"3Pb was again separated by precipitation on sodium chloride from a strongly acid solution. Advantages of the system are discussed and optimum conditions given. (U.K.).

457

The CTOF measurements and Monte Carlo analyses of neutron spectra for backward direction from iron target irradiated by protons with energies from 400 to 1200 MeV  

CERN Document Server

A calorimetric-time-of-flight (CTOF) technique was used for real-time, high-precision measurement of neutron spectrum at the angle of 175 degrees from the initial proton beam direction, which hits a face plane of a cylindrical iron target of 20 cm in diameter and 25 cm thick. A comparison was performed between the neutron spectra predicted by the MARS and the MCNPX code systems and measured by experiments for 0.4-, 0.6-, 0.8-, 1.0-, and 1.2-GeV protons.

2009-01-01

458

Target Diagnostic Instrument-Based Controls Framework for the National Ignition Facility  

Energy Technology Data Exchange (ETDEWEB)

NIF target diagnostics are being developed to observe and measure the extreme physics of targets irradiated by the 192-beam laser. The response time of target materials can be on the order of 100ps--the time it takes light to travel 3 cm--temperatures more than 100 times hotter than the surface of the sun, and pressures that exceed 109 atmospheres. Optical and x-ray diagnostics were developed and fielded to observe and record the results of the first 4-beam experiments at NIF. Hard and soft x-ray spectra were measured, and time-integrated and gated x-ray images of hydrodynamics experiments were recorded. Optical diagnostics recorded backscatter from the target, and VISAR laser velocimetry measurements were taken of laser-shocked target surfaces. Additional diagnostics are being developed and commissioned to observe and diagnose ignition implosions, including various neutron and ...

2007-05-07

459

Simulation of High Power Deposition on Target Materials: Applications in Magnetic, Inertial Fusion, and High Power Plasma Lithography Devices  

International Nuclear Information System (INIS)

High power and particle deposition on target materials are encountered in many applications including magnetic and inertial fusion devices, nuclear and high energy physics applications, and laser and discharge produced plasma devices. Surface and structural damage to plasma-facing components due to the frequent loss of plasma confinement remains a serious problem for the Tokamak reactor concept. The deposited plasma energy causes significant surface erosion, possible structural failure, and frequent plasma contamination.

2006-01-01

460

Real time neutron dosemeter response calculations  

International Nuclear Information System (INIS)

The response of a real time neutron dosemeter using a thin LiF target sandwiched between tow parallel surface barrier semiconductor detectors is studied for different neutron distributions and different angles of incidence. Calculations of the response function defined for a simultaneous detection by the two detectors of the particles emitted when the reaction "6Li(n,t)#alpha# occurs in the target are fulfilled by geometrical considerations of the reaction kinematics and the differential cross section variations. Finally, the efficiency of the studied detection systems is analyzed for dosimetric uses. (author).

1996-04-01

461

Purification of cyclotron-produced {sup 203}Pb for labeling Herceptin  

Energy Technology Data Exchange (ETDEWEB)

A simple and rapid procedure was developed for the purification of cyclotron-produced {sup 203}Pb via the {sup 203}Tl(d,2n) {sup 203}Pb reaction. A Pb(II) selective ion-exchange resin, with commercial name Pb Resin from Eichrom Technologies, Inc., was used to purify {sup 203}Pb from the cyclotron-irradiated Tl target with excellent recovery of the enriched Tl target material. The purified {sup 203}Pb was used to radiolabel the monoclonal antibody Herceptin. The in vitro and in vivo properties of the {sup 203}Pb radioimmunoconjugate were evaluated.

2005-04-01

462

Proton beam monitoring and forming on the target of isotope complex at INR linac  

International Nuclear Information System (INIS)

Special beam extraction channel is used at INR linac for isotope production. It starts from 160 MeV measuring and matching area of accelerator. This choice of beam extraction enables to direct to the target of isotope complex a proton beam of wide energy range up to 160 MeV. It is important for production of different types of nuclides. The measuring results of proton beam behavior in this region are presented. Required beam forming in 160 MeV measuring and matching area of accelerator and in beam extraction channel is discussed.

2010-01-01

463

Production of carrier-free lead-203  

Energy Technology Data Exchange (ETDEWEB)

The chemical separation of carrier-free /sup 203/Pb following deuterium bombardment of a /sup 203/Tl target is described. Coprecipitation from strontium sulphate was used to separate the /sup 203/Pb from a solution of the thallium target in sulphuric acid. The SrSO/sub 4/ precipitate was filtered, washed and dissolved in hydrochloric acid, from which /sup 203/Pb was again separated by precipitation on sodium chloride from a strongly acid solution. Advantages of the system are discussed and optimum conditions given.

1982-07-01

464

NuMI proton beam diagnostics and control: achieving 2 megawatt capability  

Energy Technology Data Exchange (ETDEWEB)

The NuMI proton beam at Fermilab currently delivers 120 GeV protons to the neutrino production target with design beam power capability to 400 kW. Upgrade capability to 700 kW is being prepared, with planning toward delivering 2.3 MW beam provided by the Project X accelerator upgrade plan. We report on the system of beam diagnostics and control used in operation of the NuMI beam. Also considered are the steps to provide a robust system for transport and targeting beam of 2 MW and beyond.

2008-10-01

465

Neural solution to the target intercept problems in a gun fire control system  

British Library Electronic Table of Contents (United Kingdom)

Time delay neural networks trained with the backpropagation algorithm are derived for the gun fire control system to correct the miss distance between a target and the projectiles from the gun. Its performance is compared to optimum linear filter based on minimum mean square error [R.E. Kalman, A new approach to linear filtering and prediction problems, J. Basic Eng. 82D (1960) 35-44.]. The structure of the proposed neural controller is described and performance results are shown.

2007-01-01

466

Near-threshold production of {omega}-mesons in the pn{yields}d{omega} reaction  

Energy Technology Data Exchange (ETDEWEB)

The first measurement of the pn{yields}d{omega} total cross-section has been achieved at mean excess energies Q{approx}28 and 57 MeV by using a deuterium cluster-jet target. The momentum of the fast deuteron was measured in the ANKE spectrometer at COSY-Juelich and that of the slow ''spectator'' proton (p{sub sp}) from the pd{yields}p{sub sp}d{omega} reaction in a silicon telescope placed close to the target. The cross-sections lie above those measured for pp{yields}pp{omega} but seem to be below theoretical predictions. (orig.)

2004-09-01

467

Modification of a gas jet transport system for the supression of heavy-mass fission product homologues  

Energy Technology Data Exchange (ETDEWEB)

The uranium target of a gas jet transport system for fission products has been modified by the addition of an aluminum cover foil. The new modification allows fission fragments of low mass to enter a continuous chemistry system while heavier fragments are stopped in the aluminum. The elimination of the heavier homologues allows development of simpler and faster chemical separation procedures. In addition, since the lighter fragments are slowed down by the cover foil a smaller target chamber can be used. This leads to a reduction in system holdup time.

1987-04-15

468

Modification of a gas jet transport system for the supression of heavy-mass fission product homologues  

International Nuclear Information System (INIS)

The uranium target of a gas jet transport system for fission products has been modified by the addition of an aluminum cover foil. The new modification allows fission fragments of low mass to enter a continuous chemistry system while heavier fragments are stopped in the aluminum. The elimination of the heavier homologues allows development of simpler and faster chemical separation procedures. In addition, since the lighter fragments are slowed down by the cover foil a smaller target chamber can be used. This leads to a reduction in system holdup time. (orig.).

469

Mechanical variations of diffused plasma parameters in a double plasma device  

International Nuclear Information System (INIS)

Experimentally it is shown that a movable grounded metallic plate placed inside a multi-dipole magnetic cage can vary the diffused plasma parameters such as density, plasma potential and electron temperature. Plasma is solely produced in the source section of a double plasma device by a dc hot filament discharge and a low-density plasma is produced in the target section by local ionization of neutral gas by the high energetic electrons coming from the source section. A grounded movable stainless steel plate is inserted in the target section of the device. The floating potential of the plate also changes depending on the position of the plate inside the magnetic cage.

2007-06-21

470

Locked nucleic acid (LNA): High affinity targeting of RNA for diagnostics and therapeutics  

DEFF Research Database (Denmark)

Locked nucleic acid (LNA) is a nucleic acid analogue containing one or more LNA nucleotide monomers with a bicyclic furanose unit locked in an RNA mimicking sugar conformation. This conformational restriction results in unprecedented hybridization affinity towards complementary single stranded RNA and thus, makes LNA uniquely suited for mimicking RNA structures and sequence specific targeting of RNA in vitro or in vivo. The focus of this paper is on LNAantisense, LNA-modified siRNA (siLNA), and detection and analysis of microRNAs by LNA-modified oligonucleotide probes.

2005-01-01

471

Inelastic electron--dipole-molecule scattering at sub-milli-electron-volt energies: HF and NH_3  

International Nuclear Information System (INIS)

Studies of destruction of very-high-n (100targets HF and NH_3 are reported. Analysis of the data using the essentially-free-electron model suggests that, for ultralow electron energies (#approx#80 #mu#eV--1.4 meV), the cross section #sigma#(var-epsilon) for rotationally inelastic scattering of electrons by a polar target varies approximately as 1/var-epsilon, where var-epsilon is the electron energy.

472

Experimental research on X-ray spectrum emitted from hot laser-produced aluminium plasma  

International Nuclear Information System (INIS)

The hot uniform aluminium plasma was produced by irradiating thin aluminium dotted foil smoothly with the 9th 0.53 ?m laser on Shenguang II laser facility. The emitted spectrum was measured from the front and tangential direction of the target with two crystal spectrometers, and the quantitative spectrum from the front of the target was obtained. The state of laser- produced plasma was simulated with the radiation hydrodynamics code MULTI-1D, and the emitted spectrum was calculated with the spectrum code of Collision-Radiation model under the simulated plasma state. The experimental spectrum accords with the simulated one. (authors)

2007-12-01

473

Experimental Study of Plasma-Surface Interaction and Material Damage Relevant to ITER Type I Elms  

International Nuclear Information System (INIS)

The paper presents experimental investigations of main features of plasma surface interaction and energy transfer to the material surface in dependence on plasma heat loads. The experiments were performed with QSPA repetitive plasma pulses of the duration of 0.25 ms and the energy density up to 2.5 MJ/m2. Surface morphology of the targets exposed to QSPA plasma screams is analyzed. Relative contribution of the Lorentz force and plasma pressure gradient to the resulting surface profile is discussed. development of cracking on the tungsten surface and swelling of the surface are found to be in strong dependence on initial temperature of the target.

2006-01-01

474

Electron beam therapy in carcinoma of the buccal mucosa  

Energy Technology Data Exchange (ETDEWEB)

Electron beam therapy has often been used for radiation therapy of carcinomas of the buccal mucosa, though side effects, including stomatitis and dermatitis, are known to exist. We experimented using the additional back scatter and transit with the phantom under a lead plate within the irradiation field, in order to better focus the dose on the target volume moreover, we fabricated a mouthpiece fitted with a lead plate shaped to the target volume, and with respect to the influence of the mouthpiece on stomatitis and dermatitis, obtained good clinical results. (author).

1990-10-01

475

Electron beam therapy in carcinoma of the buccal mucosa  

International Nuclear Information System (INIS)

Electron beam therapy has often been used for radiation therapy of carcinomas of the buccal mucosa, though side effects, including stomatitis and dermatitis, are known to exist. We experimented using the additional back scatter and transit with the phantom under a lead plate within the irradiation field, in order to better focus the dose on the target volume moreover, we fabricated a mouthpiece fitted with a lead plate shaped to the target volume, and with respect to the influence of the mouthpiece on stomatitis and dermatitis, obtained good clinical results. (author).

476

Direct dark matter identification with a hybrid detection technique  

CERN Document Server

In the quest to understand the ultimate nature of WIMPs, we propose the use of a hybrid detection technique: cylinders filled with liquefied noble gasses, acting as targets, are immersed inside a tank of Gd-doped ultra-pure water that provides an active and efficient veto against neutrons. The evaluation of the background rejection capabilities and physics potential of this instrument have been carried out through a full GEANT4 simulation, assuming the detector will be located at the Canfranc underground laboratory (in the Spanish Pyrenees). Our results compare very favourably with existing or planned experiments in the field. This technique is scalable and will allow to reach target masses of few tonnes in the next future.

2008-01-01

477

Development of three-dimensional aiming point guidance law  

British Library Electronic Table of Contents (United Kingdom)

A new aiming point guidance (APG) law in 3-dimensional space is derived analytically. The guidance law is capable of guiding the missile (interceptor) to a straight collision course with respect to the target. The missile turning rate command proportional to the error angle between the current missile heading and the predicted aim point is calculated based on the predicted target position. Performance of the APG law is numerically evaluated and compared with the proportional navigation guidance (PNG) law. The result of numerical simulation shows that the APG law is superior to the PNG law in terms of miss distance, time of interception and final stage missile turning rate demand.

2010-01-01

478

Conformal radiation therapy: technical requirements and clinical applications  

International Nuclear Information System (INIS)

Conformal radiation therapy represents a considerable and attractive challenge in oncology. Its aim is mainly to improve local control by increasing the dose with an acceptable rate of complications. This work overviews the world literature on this subject. The technical and theoretical requirements are highlighted. These requirements include a precise definition of the target volume by digital imaging (essentially CT scan), but also clear view of the target volume and the organs at risk, a specific collimation of the beam, 3-D dose calculations, optimization procedures, and a rigid immobilization of the patient with verification of his position. Moreover, the clinical applications of conformal radiation therapy are reviewed and discussed. (authors). 80 refs., 1 tab.

1995-01-01

479

Spectroscopic investigation of the charge dynamics of heavy ions penetrating solid and gaseous targets  

Energy Technology Data Exchange (ETDEWEB)

This thesis presents the study of the slowing down process of fast heavy ions inside matter. In the framework of this research, the influence of the target density on the stopping process is investigated. Experiments on the interaction of {sup 48}Ca{sup 6+}-{sup 48}Ca{sup 10+} and {sup 26}Mg{sup 5+} ion beams with initial energies of 11.4 MeV/u and 5.9 MeV/u with solid and gaseous targets have been carried out. A novel diagnostic method, X-ray spectroscopy of K-shell projectile radiation, is used to determine the ion charge state in relation to its velocity during the penetration of fast heavy ions inside the stopping material. A spatially resolved analysis of the projectile and target radiation in solids is achieved for the first time. The application of low-density silica aerogels as stopping media provided a stretching of the ion stopping length by 20 - 100 times in comparison with solid quartz. The Doppler Effect ...

2007-01-15

480

On the Utility of Antiprotons as Drivers for Inertial Confinement Fusion  

Energy Technology Data Exchange (ETDEWEB)

By contrast to the large mass, complexity and recirculating power of conventional drivers for inertial confinement fusion (ICF), antiproton annihilation offers a specific energy of 90MJ/{micro}g and thus a unique form of energy packaging and delivery. In principle, antiproton drivers could provide a profound reduction in system mass for advanced space propulsion by ICF. We examine the physics underlying the use of antiprotons ({bar p}) to drive various classes of high-yield ICF targets by the methods of volumetric ignition, hotspot ignition and fast ignition. The useable fraction of annihilation deposition energy is determined for both {bar p}-driven ablative compression and {bar p}-driven fast ignition, in association with 0-D and 1-D target burn models. Thereby, we deduce scaling laws for the number of injected antiprotons required per capsule, together with timing and focal spot requirements. The kinetic energy of the injected antiproton ...

2003-10-20

481

Mapping a nucleolar targeting sequence of an RNA binding nucleolar protein, Nop25  

International Nuclear Information System (INIS)

Nop25 is a putative RNA binding nucleolar protein associated with rRNA transcription. The present study was undertaken to determine the mechanism of Nop25 localization in the nucleolus. Deletion experiments of Nop25 amino acid sequence showed Nop25 to contain a nuclear targeting sequence in the N-terminal and a nucleolar targeting sequence in the C-terminal. By expressing derivative peptides from the C-terminal as GFP-fusion proteins in the cells, a lysine and arginine residue-enriched peptide (KRKHPRRAQDSTKKPPSATRTSKTQRRRR) allowed a GFP-fusion protein to be transported and fully retained in the nucleolus. When the peptide was fused with cMyc epitope and expressed in the cells, a cMyc epitope was then detected in the nucleolus. Nop25 did not localize in the nucleolus by deletion of the peptide from Nop25. Furthermore, deletion of a subdomain (KRKHPRRAQ) in the peptide or amino acid substitution of lysine and arginine residues in the subdomain ...

2006-06-10

482

Effects of ion-induced electron emission on magnetron plasma instabilities  

International Nuclear Information System (INIS)

Some magnetron sputtering systems experience rapid oscillations in the current and voltage of the plasma discharge after several hours when equipped with certain targets. These oscillations often lead to the plasma becoming extinguished, a condition known as ''flame-out.'' This article details the study of two 90% W--10% Ti magnetron targets which differed in density. The higher density targets sometimes experienced flame-out after approximately 3 h of sputtering. The less dense material could be sputtered for the entire 15 h life of the target. Scanning electron microscopy pictures and atomic composition depth profiles were obtained using Auger electron spectroscopy. In addition, a Colutron-based ion source with a high vacuum system was used to measure ion-induced secondary electron emission coefficients as a function of energy, ion specie, and gas coverage. Analysis of the sample from the group that ...

483

ELM resolved energy distribution studies in the JET MKII Gas-Box divertor using infra-red thermography  

International Nuclear Information System (INIS)

Using infra-red (IR) thermography, power loads onto the MKII Gas-Box divertor targets have been investigated in Type-I ELMy H-Mode plasmas at JET in medium current discharges (Ip = 2.6 MA and BT = 2.7 T). Heat fluxes are calculated from the measured divertor target tile surface temperatures taking into account the influence of co-deposited surface layers on tile surfaces. This is particularly important when estimating the energy deposition during transient events such as ELMs. Detailed energy balance analysis is used, both from IR and tile embedded thermocouples, to demonstrate an approximately constant ELM-averaged in/out divertor target asymmetry of ?0.55 and to show that the ELM in/out energy deposition ratio ranges from 1 : 1 to 2 : 1. The inter-ELM in/out ratio is close to the ELM-averaged value at low pedestal collisionalities and decreases down to values close to zero when the inner target plasma ...

2007-05-01

484

Design of a closed 4 MW spallation target module with heat removal system for an ADS system  

International Nuclear Information System (INIS)

At the Forschungszentrum Karlsruhe the HGF Strategy Fund project entitled 'Innovative Technology to Reduce Radiotoxicity' is performed which delivers an essential scientific contribution to the application oriented fundamental research for Accelerator Driven Systems (ADS). The addressed topics are in the areas of heavy liquid metal technology, thermalhydraulics and materials / corrosion. An ADS consists of three main components: an proton accelerator, a spallation target and a subcritical blanket. The strategic objective of an ADS is the transmutation of long-lived radioactive waste (plutonium, minor actinides and long-lived fission products) into short-lived isotopes or stable elements, thus closing the fuel cycle. The objective of one task of the HGF Strategy Fund Project is the numerical calculation of a closed spallation target module. In a consequent next step such a spallation target can be experimentally investigated ...

485

The study of dual energy X-ray absorptiometry on body composition components in obesity  

International Nuclear Information System (INIS)

Objective: To study the correlation of the bone mineral density (BMD) and the body composition components of body mass index (BMI), FAT and LEAN in Chinese obesity. Methods: There were 150 cases in obesity group diagnosed by BMI, including 75 males [ median age 46 years, mean weight (89.64 #+-# 8.33) kg] and 75 females [median age 45 years, mean weight (77.23 #+-# 6.85) kg]. There were 150 persons with normal BMI in the control group, including 75 males [(median age 47 years, mean weight (62.34 #+-# 5.72) kg] and 75 females [ median age 45 years, mean weight (50.16 #+-# 5.06) kg]. The body height and weight of 300 persons in two groups were measured respectively and ,simultaneously calculated the BMI. These data and the body composition parameters measured by the dual energy X-ray absorptiometry (DEXA) in these two groups were compared and analyzed. The data obtained used two-sample t-test analysis, bi-variable correlation used Pearson linear correlation analysis and multi-variable ...

2009-06-01

486

MRT versus CT in the diagnosis of pneumonia. Evaluation of a T{sub 2}-weighted utrafast turbo-spin-echo sequence (UTSE); MRT versus CT in der Diagnostik von Pneumonien. Evaluation einer T{sub 2}-gewichteten ultraschnellen Turbo-Spin-Echo-Sequenz (UTSE)  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To evaluate a T{sub 2}-weighted URSE sequence for the assessment of pulmonary infiltrations in comparison to CT. Methods: 28 MRT scans of 22 patients with confirmed pneumonia were recorded on a 1.5 Tesla apparatus with an expiratory and diastolic triggered, T{sub 2}-weighted ultrafast-spin-echo sequence in axial slice mode with the following parameters: TR{sub eff}/T{sub E}/Turbofactor 2000-4000/90 ms/21-23; slice thickness/separation 6/0.6 mm; FOV 360 mm; 24 slices. 24 spiral CTs (sice thickness/table advance: 1-2 mm/10 mm) were available for comparison. The separate evaluation of MRTs and CTs was performed by three radiologists in a consensus procedure with regard to pulmonary lesions (e.g., infiltration, round foci, net patterns) and image quality of the MRTs (4-step scale). Results: In 71% of the cases the CTs and MRTs agreed with the diagnosis and representation of the lesions, in 25% MRT was superior. MRT was better for the detection of pulmonary ...

1999-05-01

487

MRI in definition of bleeding source, lesion pattern and therapy in haemarthros of the knee; Die MRT beim Haemarthros des Kniegelenks: Bestimmung von Blutungsursachen, Verletzungsmustern und Therapie  

Energy Technology Data Exchange (ETDEWEB)

Patients with haemarthros of the knee were examined by MRI and arthroscopy to identify the bleeding source and to determine surgical or conservative therapy. A prospective study was performed on 120 patients who underwent MRI and arthroscopy, point lesions and bleeding sources were documented separately on a standardised form. Arthroscopy demonstrated a ruptured anterior cruciate ligament in 86%, meniscal tears in 55%, disruption of collateral ligaments in 17%, osteochondral lesions in 5% and tears of capsule or plicae in 13%. Disruption of cruciate ligaments caused haemorrhage in all but three cases. In contrast, only meniscal tears located very adjacent to the meniscal basement had bled. Those types of osteochondral lesions caused haemorrhage characterised on MRI by destruction of the subchondral plate and overlying cartilage. Severe lesions of the knee were diagnosed by MRI in 71% to 100%, slight lesions in 13% to 40% of the cases. Single, combined and bland ...

1996-09-01

488

Target fabrication of low-density and nano porous materials to generate extreme ultraviolet (EUV)  

Energy Technology Data Exchange (ETDEWEB)

Our institute has been investigating laser-produced tin, lithium and xenon plasma for extreme ultraviolet (EUV) light source of EUV lithography system, and found the highest conversion efficiency of 3% at 13.5 nm in 2% bandwidth. In the present paper, we introduce fabrication methods of density-controlled tin targets to generate relatively monochromatic EUV, and higher conversion efficiency than bulk tin. The first method is the nano-template method, where liquid tin solution was immersed into a polymer film with monodispersed size nano-particle. The density can be controlled by tin concentration of the solution. The target can be classified into mass-limited target. We have shown a tendency of monochromatic EUV emission around 13.5 nm with decreasing of tin density. The intensity was higher than tin foil with bulk density. The tendency has a merit to mitigate heat effect of the first EUV mirror. The fabrication method has ...

2006-06-15

489

Target fabrication of low-density and nano porous materials to generate extreme ultraviolet (EUV)  

International Nuclear Information System (INIS)

Our institute has been investigating laser-produced tin, lithium and xenon plasma for extreme ultraviolet (EUV) light source of EUV lithography system, and found the highest conversion efficiency of 3% at 13.5 nm in 2% bandwidth. In the present paper, we introduce fabrication methods of density-controlled tin targets to generate relatively monochromatic EUV, and higher conversion efficiency than bulk tin. The first method is the nano-template method, where liquid tin solution was immersed into a polymer film with monodispersed size nano-particle. The density can be controlled by tin concentration of the solution. The target can be classified into mass-limited target. We have shown a tendency of monochromatic EUV emission around 13.5 nm with decreasing of tin density. The intensity was higher than tin foil with bulk density. The tendency has a merit to mitigate heat effect of the first EUV mirror. The fabrication method has ...

2006-06-01

490

Co-product extraction studies on N-reactor PT-57 target materials  

International Nuclear Information System (INIS)

Single pellets (of approximately 70 g each) of irradiated lithium aluminate target from N-Reactor test PT-57 were used in a series of experiments to determine the extent to which the product tritium can be recovered by (a) vacuum outgassing of the target (thermal extraction-TX) and (b) in-vacuo chemical dissolution of the target in molten sodium tetraborate (flux extraction-FX). Five TX runs and seven FX runs were made. Thirty-five percent of the tritium was recovered in a form non-condensable at -196"0C. The remainder was recovered in a condensable form (as T_2O, HTO, etc.). Post-extraction analysis of the melt from the seven flux extractions showed that a maximum of 2 percent of the original amount of tritium remained and that target dissolution was essentially complete in 12 hours. Flux extraction of two pellets which had been subjected to thermal extraction showed less than 0.4 percent of the ...

491

Activation analysis of trace elements in titanium-molybdate target used for pre-formed TiMo gel based "9"9"mTc generator production and radionuclidic impurity of "9"9"mTc pertechnetate eluate  

International Nuclear Information System (INIS)

A gel-type "9"9Mo-"9"9"mTc generator using Titanium-Molybdate target (TiMo-target) as column packing was developed in Radioisotope Department, the Dalat Nuclear Research Institute [1]. The concentration of trace elements in TiMo-target and radionuclidic purity in "9"9"mTc solution eluted from this type of generator were studied for quality control purpose. The monostandard method in neutron activation analysis has been applied to determine the concentration of trace impurities in titanium-molybdate target. For neutron activation analysis, TiMo samples were irradiated in the different channels of nuclear reactor IVV-9 at a neutron flux of maximum 2.1 x 10"1"3 n.cm"-"2s"-"1. The following chemical element impurities were determined: Na, W, Co, Fe, Zn, Ag, Sb and Cr. The gamma ray emitted nuclides found in "9"9"mTc solution eluted from our "9"9"mTc generator were the following: "6"5Zn, "6"0Co, "1"1"0"mAg, ...

2004-06-01