WorldWideScience
1

Synovial cysts of the lumbar spine: CT and MRI correlations  

Energy Technology Data Exchange (ETDEWEB)

Intraspinal synovial cysts were diagnosed in six patients during a 5-year period and retrospectively studied. Plain films of the lumbar spine showed degenerative changes in all patients. Lumbar myelography showed a posterior and lateral defect caused by extradural compression. Using CT without contrast enhancement established the diagnosis in five of the six patients. In four cases MRI was performed, three before and after injection of gadolinium diethyline-triamine penta-acetic acid (Gd-DTPA). Including the patient with a false-negative CT, MRI was positive in all patients. (orig.)

1994-08-01

2

Dura thickening adjacent to intracranial tumors on MRI. Histologically correlation  

International Nuclear Information System (INIS)

Purpose: With intracranial tumors a flat, contrast-enhancing, probably dural structure adjacent to the tumor can occasionally be observed on gadolinium-DTPA enhanced MR images. Therefore we have attempted to evaluate a tumor infiltration of this enthancement on MRI. Material and Methods: This study included 50 patients. 19 patients had a dural thickening at the tumor base (13 meningiomas and 6 metastases), while 31 patients did not (12 meningiomas and 19 metastases). Studies included plane T_2-weighted spin echo (SE) images as well as T_1-weighted axial, coronal, or sagittal plains with and without contrast agent. Histopathological examinations, were done on the tumor base adjacent to the dura mater. Results: 7 of 12 meningiomas showed a meningeal thickening on MRI with histopathologically proven tumor infiltration as did also 5 of 6 metastases. But 3 of 12 meningiomas and 15 of 19 metastases without ...

3

Regional Convection-Enhanced Delivery of Gadolinium-labeled Albumin in the Rat Hippocampus In Vivo  

UK PubMed Central (United Kingdom)

Convection-enhanced delivery (CED) has emerged as a promising method of targeted drug-delivery for treating central nervous system (CNS) disorders, but the influence of brain structure on infusate...Full Text Available

2010-03-15

4

Convection-enhanced Delivery of Free Gadolinium with the Recombinant Immunotoxin MR1-1  

UK PubMed Central (United Kingdom)

PurposeA major obstacle in glioblastoma (GBM) therapy is the restrictive nature of the blood-brain barrier (BBB). Convection-enhanced delivery (CED) is a novel method...Full Text Available

2010-05-01

5

Monte-Carlo-based simulation of LWR cores with innovative fuel concepts  

International Nuclear Information System (INIS)

High resolution Monte-Carlo simulations show that the neutron spectrum, fuel burnup and fuel temperature feedback effect of a PWR core loaded with Thoria-based fuel (Th/Pu-O_2) do not significantly differ from the MOX fuelled one due to the similar neutronic characteristics of both fertile materials (Th-232, U-238). The core physics of this fuel variant is characterized by an enhanced moderator/void temperature coefficient (by factor 2.4) and high incineration rate for Pu (approx. 60 %). A PWR core loaded with the Molybdenum-based inert matrix fuel (IMF) - in contrast to MOX-, shows a harder spectrum, resulting in small temperature coefficients of reactivity and particularly in a higher fuel depletion rate as well as an enhanced TRU reduction performance. The incineration of Pu amounts to 46 % resulting, in turn, in generation of minor actinides of about 10 % of the total Pu consumption. The higher excess reactivity ...

2009-05-03

6

Ganglioneuromas in childhood: MRI and CT characteristics  

International Nuclear Information System (INIS)

Purpose: The aim of this study was to demonstrate the typical appearance of ganglioneuromas in computer-assisted tomography (CT), and magnetic resonance imaging (MRI). Material and methods: Retrospective analysis of diagnostic imaging (9 CT, 6 MRI) in 9 children aged 3 to 15 years with the histological diagnosis of ganglioneuroma. Results: The tomographies showed large (max. 13.4 cm in diameter) round or oval tumors with sharp delineation. The sites of the tumors were the retroperitoneum (5), the mediastinum (3), and the adrenal gland (1). Intraspinal tumor involvement occurred in 4 cases. On comparing CT with MRI, MRI was more accurate in defining the intraspinal involvement. The ganglioneuromas were of hypodense appearance in the native CT scan and showed moderate enhancement upon administration of contrast media. In five patients tumor calcifications with a disseminated sprinkled pattern were seen in CT. In MRI T_1-weighted scans the tumors ...

2000-05-01

7

Assessment of PET and MRI Polar Map using Gaussian Mixture Model  

International Nuclear Information System (INIS)

Cardiac disease research relies increasingly on small animal models and non-invasive imaging methods such as positron emission tomography (PET) and magnetic resonance imaging (MRI). Delayed enhancement magnetic resonance imaging (DE-MRI) using gadolinium-based contrast agents appear to be a visualizing infracted myocardium with high spatial resolution. Polar map (or bull's-eye image) was used to determination of the myocardial infarction area. Polar map is a comprehensive interpretation of the left ventricle. The infarct size was computed as the fraction of the total polar map areas. The threshold was computed as the percentage of mean intensity of the normal region. In other study, 50% predefined threshold value in varying range (30?70%) was most commonly use. However, predefined threshold value isn't acceptance in all case. The purpose of this study was to investigate methodological approach for automatic measurement of ...

2010-10-01

8

Ultrasmall superparamagnetic iron oxides (USPIOs): a future alternative magnetic resonance (MR) contrast agent for patients at risk for nephrogenic systemic fibrosis (NSF)?  

UK PubMed Central (United Kingdom)

Gadolinium (Gd) based contrast agents (GBCAs) in magnetic resonance imaging (MRI) are used in daily clinical practice and appear safe in most patients; however, nephrogenic systemic fibrosis...Full Text Available

2009-03-01

9

First experiences with application of gadolinium-DTPA in infants and small children under two years of age  

International Nuclear Information System (INIS)

The use of Gadolinium-DTPA as a paramagnetic contrast agent in MRI with adults and juveniles concerning brain and spinal cord pathology is well proven since years. In the FRG it is only introduced for children over two years of age. Therefore this report deales with the experience in four infants and small children under the age of two. They all were suffering from neurological tumors and got additional diagnostic information in three cases. Clinical side-effects like urticaria, vomiting or convulsions had not been observed nor had pathologic changes of the biochemical parameters been noticed. (orig./GDG).

10

Neurosarcoidosis--demonstration of meningeal disease by gadolinium enhanced magnetic resonance imaging.  

UK PubMed Central (United Kingdom)

Arriving at a firm diagnosis of neurosarcoidosis continues to pose serious problems, particularly when evidence of granulomatous disease outside the nervous system is lacking. The commonest mode of...Full Text Available

1991-06-01

11

Nephrogenic systemic fibrosis after application of gadolinium-based contrast agents - a status paper; Nephrogene systemische Fibrose nach Anwendung gadoliniumhaltiger Kontrastmittel - ein Statuspapier zum aktuellen Stand des Wissens  

Energy Technology Data Exchange (ETDEWEB)

Recently the association of a rare disease named ''nephrogenic systemic fibrosis'' (NSF) with the administration of gadolinium-containing contrast media, especially gadodiamide (Omniscan, GE-Healthcare), was described. NSF is a scleroderma-like disease characterised by widespread tissue fibrosis. Until now, NSF cases were observed only in patients with kidney disease. Almost all patients were suffering from chronic renal insufficiency, 90 % of them required renal replacement therapy. The true incidence of the disease is unknown. First retrospective analyses of selected collectives of patients with end-stage renal disease showed 2 - 5 % cases of NSF after administration of Gadolinium-containing contrast agents with an odds ratio of 20 - 50 in comparison to non-exposed controls. NSF is a serious adverse reaction, which may result in severe disabilities and even death. ...

2007-06-15

12

3D time-of-flight MR angiography of the intracranial vessels: optimization of the technique with water excitation, parallel acquisition, eight-channel phased-array head coil and low-dose contrast administration  

Energy Technology Data Exchange (ETDEWEB)

The aim of this study is three folds: to compare the eight-channel phased-array and standard circularly polarized (CP) head coils in visualiazation of the intracranial vessels, to compare the three-dimentional (3D) time-of-flight (TOF) MR angiography (MRA) techniques, and to define the effects of parallel imaging in 3D TOF MRA. Fifteen healthy volunteers underwent 3D TOF MRA of the intracranial vessels using eight-channel phased-array and CP standard head coils. The following MRA techniques were obtained on each volunteer: (1) conventional 3D TOF MRA with magnetization transfer; (2) 3D TOF MRA with water excitation for background suppression; and (3) low-dose (0.5 ml) gadolinium-enhanced 3D TOF MRA with water excitation. Results are demonstrating that water excitation is a valuable background suppression technique, especially when applied with an eight-channel phased-array head coil. For central and proximal portions of the intracranial arteries, unenhanced TOF MRA ...

2004-11-01

13

Characteristic features of intracranial meningiomas on magnetic resonance tomography  

International Nuclear Information System (INIS)

Twenty-three patients with intracranial meningiomas were examined by means of magnetic resonance tomography (MRT). In 13 patients the paramagnetic contrast medium gadolinium DTPA was used. Meningiomas show only slight changes in signal intensity compared with brain in the spin-echo mode, the greatest contrast being found on photon density images (TR 1600 ms, TE 35 ms). In T1 images more than 50% of the patients showed a low signal margin between tumour and brain. Hyperostosis of the calvarium is easily recognised, but MRT is unreliable for showing tumour calcification. After intravenous injection of gadolinium DTPA, there was marked homogeneous uptake in the meningiomas. These signs are useful for the diagnosis of a meningioma by MRT. (orig.).

14

Dialysis and contrast media  

Energy Technology Data Exchange (ETDEWEB)

In a previous survey we revealed uncertainty among responders about (a) whether or not to perform hemodialysis in patients with severely reduced renal function who had received contrast medium; and (b) when to perform hemodialysis in patients on regular treatment with hemodialysis or continuous ambulatory dialysis who received contrast medium. Therefore, the Contrast Media Safety Committee of The European Society of Urogenital Radiology decided to review the literature and to issue guidelines. The committee performed a Medline search. Based on this, a report and guidelines were prepared. The report was discussed at the Ninth European Symposium on Urogenital Radiology in Genoa, Italy. Hemodialysis and peritoneal dialysis safely remove both iodinated and gadolinium-based contrast media. The effectiveness of hemodialysis depends on many factors including blood and dialysate flow rate, ...

2002-12-01

16

Dura thickening adjacent to intracranial tumors on MRI. Histologically correlation; Duraverdickung am Rand intrakranieller, duranaher Raumforderungen in der MRT. Histologische Korrelation  

Energy Technology Data Exchange (ETDEWEB)

Purpose: With intracranial tumors a flat, contrast-enhancing, probably dural structure adjacent to the tumor can occasionally be observed on gadolinium-DTPA enhanced MR images. Therefore we have attempted to evaluate a tumor infiltration of this enthancement on MRI. Material and Methods: This study included 50 patients. 19 patients had a dural thickening at the tumor base (13 meningiomas and 6 metastases), while 31 patients did not (12 meningiomas and 19 metastases). Studies included plane T{sub 2}-weighted spin echo (SE) images as well as T{sub 1}-weighted axial, coronal, or sagittal plains with and without contrast agent. Histopathological examinations, were done on the tumor base adjacent to the dura mater. Results: 7 of 12 meningiomas showed a meningeal thickening on MRI with histopathologically proven tumor infiltration as did also 5 of 6 metastases. But 3 of 12 meningiomas and 15 of 19 metastases ...

1997-11-01

17

Value of MRCP using oral Gd-DTPA as negative contrast materials in diagnosis of atypical juxtapapillary duodenal diverticulum  

British Library Electronic Table of Contents (United Kingdom)

Objective To investigate value of magnetic resonance cholangiopancreatography (MRCP) using oral diluted gadolinium (Gd)-diethylenetriamine penta-acetic acid (DTPA) as negative contrast materials in diagnosis of juxtapapillary duodenal diverticulum with atypical imaging features. Methods Nineteen patients with juxtapapillary duodenal diverticula of which imaging findings were atypical underwent MRCP using oral diluted Gd-DTPA as negative contrast materials after conventional MRCP without any oral contrast materials. Results Twenty diverticula were revealed in the 19 patients. At conventional MRCP, the diverticula appeared as rounded lesion with high signal intensity. After oral administration of diluted Gd-DTPA, they disappeared at MRCP. These entities were diagnosed as duodenal diverticula...

2009-01-01

18

The diagnostic value of MRI and gadolinium-DTPA compared with CT for the diagnosis of bladder tumours  

International Nuclear Information System (INIS)

In a prospective study, 58 patients with carcinomas of the bladder were examined by CT and MRI; in 48, gadolinium-DTPA was administered intravenously. MRI provided exact staging in 89%, compared with 80% with CT. There was 13% over-staging with CT and 11% with MRI. MRI, unlike CT did not result in any under-staging. In 36 patients a quotient could be calculated from the signal intensity of the tumour and surrounding soft tissues both before and after the intravenous contrast medium and the increased quotient after contrast administration could be estimated. There was a significant increase in the tumour/muscle quotient with a mean of 72#+-#22% (minimum 43%, maximum 153%), corresponding to a marked increase of the signal form the tumour when compared with the precontrast images. This had the following advantages compared with CT: Accurate differentiation between superficial and intramural spread. MRI was better than CT at ...

19

Differential diagnosis by CT units with contrast enhancement  

Energy Technology Data Exchange (ETDEWEB)

Variation of CT units, in organs, before and after using contrast enhancing medium was reviewed and personal experience was presented. In the normal brain CT units was little changed by contrast enhancement (CE), whereas remarkable change was observed at lesions. No difference of CT units was observed between the normal liver and hepatomas. The normal kidney had higher CE effect than hypernephromas suggesting an increase of the sensitivity. CE was not found in cysts or necrosis. The changes of CT units in the cases of cerebral diseases are tabled with various contrast medium and scanners.

1981-04-01

20

Dynamic NMR effects in breast cancer dynamic-contrast-enhanced MRI  

UK PubMed Central (United Kingdom)

The passage of a vascular-injected paramagnetic contrast reagent (CR) bolus through a region-of-interest affects tissue 1H2O relaxation and thus MR image intensity. For longitudinal...Full Text Available

2008-11-18

21

Contrast factors in nuclear magnetic resonance imaging  

International Nuclear Information System (INIS)

In Nuclear Magnetic Resonance (NMR) imaging, contrast is dependent on the emission of radiofrequency waves by atomic nuclei, balanced by several parameters. The high information content of NMR images is due to the multiplicity of its parameters. However, this advantage introduces a difficulty in the interpretation of the contrast. There are three contrast parameters for each tissue: hydrogen nuclei density; relaxation time T1; relaxation time T2. Contrast may be enhanced towards any of these parameters by increasing the emission of radiowaves by atomic nuclei using particular pulse sequences.

1985-01-01

22

RBS Characterization of Yttrium Iron Garnet Thin Films  

International Nuclear Information System (INIS)

Magnetic materials such as yttrium iron garnet (YIG) are of great importance for its magneto-optic properties and for their potential applications in the domain of optical telecommunications. The deposition of thin films of YIG, on quartz or GGG (gadolinium gallium garnet) substrate, was performed using radio frequency non reactive magnetron sputtering, followed by high temperature annealing which is needed to enhance the crystallinity of the layers. Rutherford backscattering spectrometry RBS was used to determine the thickness and stoichiometry of the performed layers in order to investigate correlations between growth conditions and the quality of the final material. RBS measurements showed the influence of the deposition time and the temperature substrate on the film growth and its stoichiometry. (author)

2008-12-13

23

CT diagnosis of intrahepatic cholangiocarcinoma  

International Nuclear Information System (INIS)

Purpose: To evaluate contrast-enhanced CT scan in the diagnosis of intrahepatic cholangiocarcinoma by correlating the CT appearance with pathologic specimens. Materials and methods: Twenty-eight patients with pathologically proven intrahepatic cholangiocarcinoma were examined. Unenhanced abdominal CT study were performed in 28 patients; conventional contrast-enhanced CT in 27 patients. Enhanced CT scan including fast injection, fast scan and delayed scan at the largest section of the lesion was done in 7 patients. Contiguous 10 mm CT scans of the surgical specimens were also obtained in 8 patients. The preoperative and specimen CT scans in these 8 patients were compared with the corresponding pathological sections. A total of 103 areas of the pathological sections was compared with the CT appearances. Results: All lesions contained areas of delayed contrast enhancement and/or no ...

25

Gd-25 DTPA-MAb, a potential NMR contrast agent for MRI in the xenografted nude mouse: preliminary studies  

Energy Technology Data Exchange (ETDEWEB)

Monoclonal antibodies (MAbs) 19-9 and 73-3 specific for human colon adenocarcinoma were labelled with a high number of gadolinium atoms. Twenty five DTPA were chelated per MAb, with only slight loss of immunoreactivity. The NMR contrast agent Gd-25 DTPA-MAb 19-9 or 73-3 ((Gd) 17 mumole/kg, (MAb) 60 microM) was injected into nude mice bearing human colon adenocarcinoma (SW948). Tumors were removed 24 hr after injection and T1 was measured in vitro. T1 relaxation time varied according to MAb specificity against tumour targets; T1 decreased 20% for MAb 19-9 and MAb 73-3 with SW948 tumor. Imaging was performed with this model. Very good contrast was obtained 24 hr after Gd-25 DTPA-MAb injection.

1988-01-01

26

Ganglioneuromas in childhood: MRI and CT characteristics; Ganglioneurome im Kindesalter: CT- und MRT-Charakteristika  

Energy Technology Data Exchange (ETDEWEB)

Purpose: The aim of this study was to demonstrate the typical appearance of ganglioneuromas in computer-assisted tomography (CT), and magnetic resonance imaging (MRI). Material and methods: Retrospective analysis of diagnostic imaging (9 CT, 6 MRI) in 9 children aged 3 to 15 years with the histological diagnosis of ganglioneuroma. Results: The tomographies showed large (max. 13.4 cm in diameter) round or oval tumors with sharp delineation. The sites of the tumors were the retroperitoneum (5), the mediastinum (3), and the adrenal gland (1). Intraspinal tumor involvement occurred in 4 cases. On comparing CT with MRI, MRI was more accurate in defining the intraspinal involvement. The ganglioneuromas were of hypodense appearance in the native CT scan and showed moderate enhancement upon administration of contrast media. In five patients tumor calcifications with a disseminated sprinkled pattern were seen in CT. In MRI T{sub 1}-weighted scans the ...

2000-05-01

27

Enhancing fraction measured using dynamic contrast-enhanced MRI predicts disease-free survival in patients with carcinoma of the cervix  

UK PubMed Central (United Kingdom)

Background:There is a need for simple imaging parameters capable of predicting therapeutic outcome.Methods:This retrospective study analysed 50 patients...Full Text Available

2010-01-05

28

Enhanced CT and CT virtual endoscopy in diagnosis of heterotopic pancreas  

UK PubMed Central (United Kingdom)

AIM: To improve the diagnosis of heterotopic pancreas by the use of contrast-enhanced computed tomography (CT) imaging and CT virtual endoscopy (CTVE).METHODS: A total of six patients with heterotopic...Full Text Available

2011-09-07

29

The use of magnetic resonance imaging for diagnosis and staging of renal cell carcinoma  

International Nuclear Information System (INIS)

The use of magnetic resonance imaging for diagnosis and the preoperative staging of renal cell carconoma was evaluated in 79 patients with 88 tumors. Gradient-echo and spin-echo images before and after intravenous administration of Gadolinium DTPA were compared with the results of computed tomography (CT) and histologic staging. The two imaging techniques had comparable results: T-stage was predicted correctly with CT in 78%.4% and with MRI in 84.0% of the cases, while the N-stage was accurately assessed in 81.8% and 79.5%, respectively. MRI had some advantages in diagnosing perirental tumor spread and in excluding an infiltration beyond Gerota's fascia. Therefore, MRI is a true alternative to CT for staging large renal cell carcinomas and especially for patients with contraindications for iodinated contrast agents. (orig.).

30

Real time neutron radiography using a Lixi neutron imaging device  

Energy Technology Data Exchange (ETDEWEB)

A real time neutron radiography system has been developed at the University of Michigan Phoenix Memorial Laboratory (PML) and has recently been used to test the imaging capabilities of a neutron imaging device developed by Lixi, Inc. of Downers Grove, Illinois. This device uses an input phosphor that is high in gadolinium to generate a light image which is then sent through an intensifier stage to provide images that can be viewed by eye, video camera, or standard 35 mm camera. It was determined that this device provides images of much higher resolution and sensitivity than those obtained with the imaging system currently being used at PML. Using computerized image enhancement techniques, the images obtained with the Lixi neutron imaging device can then be further enhanced or processed to obtain quantitative information on the object being imaged.

1986-01-15

31

Real time neutron radiography using a Lixi neutron imaging device  

International Nuclear Information System (INIS)

A real time neutron radiography system has been developed at the University of Michigan Phoenix Memorial Laboratory (PML) and has recently been used to test the imaging capabilities of a neutron imaging device developed by Lixi, Inc. of Downers Grove, Ill. This device uses an input phosphor that is high in gadolinium to generate a light image which is then sent through an intensifier stage to provide images that can be viewed by eye, video camera, or standard 35 mm camera. It was determined that this device provides images of much higher resolution and sensitivity than those obtained with the imaging system currently being used at PML. Using computerized image enhancement techniques, the images obtained with the Lixi neutron imaging device can then be further enhanced or processed to obtain quantitative information on the object being imaged. (orig.).

1986-01-01

32

Gadolinium electronic band structure: augmented plane wave calculation  

International Nuclear Information System (INIS)

Augmented plane wave calculation of gadolinium electronic structure crystallized in a hexagonal close-packed lattice is carried out.

33

Is hepatotropic contrast enhanced MR a more effective method in differential diagnosis of hemangioma than multi-phase CT and unenhanced MR?  

UK PubMed Central (United Kingdom)

BackgroundCavernous hemangiomas are the most frequent neoplasms of the liver and in routine clinical practice they often need to be differentiated from malignant tumors and other...Full Text Available

34

Magnetic resonance imaging in acute intractional tuberculosis  

International Nuclear Information System (INIS)

We reported three cases of acute intracranial tuberculosis including miliary tuberculosis, basal meningitis, tuberculomas and neuritis of cranial nerves. All patients had native and contrast enhanced CT and MRI scans. MRI revealed more granulomas and a better imaging contrast in the detection of basal meningitis. Neuritis was diagnosed only with the MRI. MRI scans should be prefered as the imaging procedure in clinically presumed intracranial tuberculosis. (orig.).

35

Hilar cholangiocarcinoma: MR correlation with surgical and histological findings  

International Nuclear Information System (INIS)

Aim: To evaluate magnetic resonance cholangiography (MRC) with high-resolution dynamic gadolinium-enhanced magnetic resonance imaging (MRI) in determining the imaging features of hilar cholangiocarcinoma that relate to tumour extent and influence resectability. Materials and methods: Twenty-six patients that underwent resection were reviewed. Tumour location and extent, lobar atrophy, the degree of portal vein and hepatic artery involvement were recorded. The findings were correlated with surgical and histopathological findings. Results: Biliary assessment was concordant in 14 and discordant in eight of 14 stented and four of 12 non-stented patients. In 63/82 veins and 43/74 arteries results were fully concordant. The mean sensitivity, specificity, positive and negative predictive values (PPV, NPV) in predicting involvement of the main portal vein (MPV) at surgery were 83.3, 100, 100, and 92.5%; of the left main branch of the portal vein (LPV) were 100, 91.6, 93.3, ...

2010-10-01

36

Precipitation, phase transformation, and enhanced diffusion in ion-implanted silicon  

International Nuclear Information System (INIS)

This paper describes Z-contrast scanning transmission electron microscopy used to study the connection between dopant precipitation and phase transformation in high dose In"+ and Sb"+ implanted Si. In the case of In, the observations confirm a heterogeneous nucleation model. Images of the precursor precipitates give the first measurement of the diffusion coefficient in amorphous Si, with an enhancement of 10"7 over tracer crystalline values. With Sb"+ implants enhanced homogeneous nucleation is observed. The connection between these results and the transient enhanced diffusion observed in crystallized Si is discussed.

37

Magnetic resonance imaging in multiple sclerosis. Imagerie nouvelle par resonance magnetique nucleaire au cours de la sclerose en plaques  

Energy Technology Data Exchange (ETDEWEB)

Magnetic resonance imaging (MRI) has rapidly attained a major position among the examinations used in the diagnostic approach of multiple sclerosis because it is highly sensitive in demonstrating lesions. However, these lesional images may have several meanings, and there is the problem of distinguishing between oedema, which is said to reflect recent lesions, and gliosis which is thought to betray old lesions. The intrinsic MRI parameters studied (i.e. relaxation times) are unable to make this distinction, whereas it is provided by paramagnetic contrast media such as gadolinium. There is no correlation between the changes observed at MRI and the severity of the disease. Another problem is the accuracy of lesion localization, since visualization is predominantly macroscopic. This raises several questions about the demonstration of correlations between clinical signs and site of the lesion(s). At the moment, several teams of neuroradiologists ...

1991-09-15

38

Ultrastructural Evidence of Dermal Gadolinium Deposits in a Patient with Nephrogenic Systemic Fibrosis and End-Stage Renal Disease  

UK PubMed Central (United Kingdom)

Background and objectives: The pathogenesis of acquired nephrogenic systemic fibrosis recently described for patients with renal insufficiency and a history of exposition to gadolinium-based magnetic...Full Text Available

2008-07-01

39

Moment of inertia calculations for some even-even rare earth nuclei  

International Nuclear Information System (INIS)

... angular momentum cranking model even-even nuclei gadolinium 156 governor

41

Electrical biasing and voltage contrast imaging in a focused ion beam system  

Energy Technology Data Exchange (ETDEWEB)

We present two new techniques that enhance conventional focused ion beam (FIB) system capabilities for integrated circuit (IC) analysis: in situ electrical biasing and voltage contrast imaging. We have used in situ electrical biasing to enable a number of advanced failure analysis applications including (1) real time evaluation of device electrical behavior during milling and deposition, (2) verification of IC functional modifications without removal from the FIB system, and (3) ultraprecision control for cross sectioning of deep submicron structures, such as programmed amorphous silicon antifuses. We have also developed FIB system voltage contrast imaging that can be used for a variety of failure analysis applications. The use of passive voltage contrast imaging for defect localization and for navigation on planarized devices will be illustrated. In addition, we describe new, biased voltage ...

1995-09-01

42

Enhancement pattern of hilar cholangiocarcinoma: Contrast-enhanced ultrasound versus contrast-enhanced computed tomography  

International Nuclear Information System (INIS)

Objective: To compare the enhancement pattern of hilar cholangiocarcinoma on contrast-enhanced ultrasound (CEUS) with that on contrast-enhanced computed tomography (CECT). Methods: Thirty-two consecutive patients with pathologically proven hilar cholangiocarcinomas were evaluated by both low mechanical index CEUS and CECT. The enhancement feature of the tumor, portal vein infiltration, and lesion conspicuity on them was investigated. Results: In the arterial phase, the numbers of the lesions showing hyperenhancement, isoenhancement, and hypoenhancement, were 14 (43.8%), 14 (43.8%), and 4 (12.6%), on CEUS, and 12 (37.5%), 9 (28.1%), and 11 (34.4%), on CECT (P = 0.162). In portal phase, the numbers of the lesions showing hypoenhancement, isoenhancement, and hyperenhancement were 30 (93.8%), 1 (3.1%), and 1 (3.1%), on CEUS, and 23 (71.9%), 8 (25.0%), and 1 (3.1%), on CECT (P = 0.046). The detection rates ...

2010-08-01

43

Pituitary disease in childhood: utility of magnetic resonance; Patologia hipofisaria en la edad pediatrica: unidad de la resonance magnetica  

Energy Technology Data Exchange (ETDEWEB)

To assess the utility of magnetic resonance (MR) imaging in the study of pediatric patients with clinical suspicion of pituitary disease. We studied 18 patients aged 7 to 18 years.Fifteen had hormonal disturbances, two presented amenorrhea and 1 complained of headache, fever and symptoms of polyuria and polydipsia. All the patients were examined using a Siemens SP 42 1-Tesla MRI scanner. Sagittal and coronal T1-weighted spin-echo images were obtained; in addition T2-weighted spin-echo or fast spin-echo imaging was performed in ten cases and intravenous gadolinium was administered in nine. We found 9 patients with hypothalamic-pituitary dysgenesis, 2 with germinoma, 2 cases of pituitary hemosiderosis in patients with thalassemia, 2 cases of microadenoma, one abscess, one case of idiopathic central diabetes insipidus and one of Langerhans cell histiocytosis. MR enabled us to assess pituitary structural alterations in children with hypothalamic-pituitary hormone ...

2000-07-01

44

Phase- and size-adjusted CT cut-off for differentiating neoplastic lesions from normal colon in contrast-enhanced CT colonography  

Energy Technology Data Exchange (ETDEWEB)

A computed tomography (CT) cut-off for differentiating neoplastic lesions (polyps/carcinoma) from normal colon in contrast-enhanced CT colonography (CTC) relating to the contrast phase and lesion size is determined. CT values of 64 colonic lesions (27 polyps <10 mm, 13 polyps {>=}10 mm, 24 carcinomas) were determined by region-of-interest (ROI) measurements in 38 patients who underwent contrast-enhanced CTC. In addition, the height (H) of the colonic lesions was measured in CT. CT values were also measured in the aorta (A), superior mesenteric vein (V) and colonic wall. The contrast phase was defined by xA + (1 - x)V using x as a weighting factor for describing the different contrast phases ranging from the pure arterial phase (x=1) over the intermediate phases (x=0.9-0.1) to the pure venous phase (x=0). The CT values of the lesions were correlated with their height ...

2004-12-01

45

Methodological study of hemodynamic analysis of lung mass by contrast enhanced dynamic CT  

Energy Technology Data Exchange (ETDEWEB)

We investigated a method of analyzing the hemodynamics of the lung mass by contrast enhanced dynamic computed tomography (dynamic CT) to determine the difference in vascular supply between the pulmonary artery and bronchial artery using an experimental model. Our experimental model consisted of two injectors connected to two tubes, representing the pulmonary artery and bronchial artery, which were further connected to a chamber representing the lung mass. Following infusion of contrast medium into each tube with some delay time, dynamic CT scans were performed to obtain time density curves of the two tubes and the chamber. Using the time-density curve of contrast passage, flow rates from the two tubes into the chamber were calculated by the curve fitting method. Calculated values correlated well with the adopted flow rates of fluid from the injectors (r=0.893) in the experiment. The results indicate our ...

1996-06-01

46

Methodological study of hemodynamic analysis of lung mass by contrast enhanced dynamic CT  

International Nuclear Information System (INIS)

We investigated a method of analyzing the hemodynamics of the lung mass by contrast enhanced dynamic computed tomography (dynamic CT) to determine the difference in vascular supply between the pulmonary artery and bronchial artery using an experimental model. Our experimental model consisted of two injectors connected to two tubes, representing the pulmonary artery and bronchial artery, which were further connected to a chamber representing the lung mass. Following infusion of contrast medium into each tube with some delay time, dynamic CT scans were performed to obtain time density curves of the two tubes and the chamber. Using the time-density curve of contrast passage, flow rates from the two tubes into the chamber were calculated by the curve fitting method. Calculated values correlated well with the adopted flow rates of fluid from the injectors (r=0.893) in the experiment. The results indicate our ...

47

3D MRI of the colon: methods and first results of 5 patients; 3D-MRT des Kolons: Methodik und erste Ergebnisse  

Energy Technology Data Exchange (ETDEWEB)

Purpose: `Exoscopic` and endoscopic identification of colorectal pathologies via MRI. Methods: 5 patients (36-88 years), two normal and three with different colorectal pathologies (diverticular disease, polyps and carcinoma of the colon), were examined by MRI after colonoscopy. Subsequent to filling of the colon with a gadolinium-water mixture under MRI-monitoring, 3D-data sets of the colon were acquired in prone and supine positions over a 28 sec breathold interval. Subsequently multiplanar T{sub 1}-weighted 2D-sequences were acquired before and following i.v. administration of Gd-DTPA (0.1 mmol/kg BW). All imaging was performed in the coronal orientation. The 3D-data were interactively analysed based on various displays: Maximum intensity projection (MIP), surface shadowed display (SSD), multiplanar reconstruction (MPR), virtual colonoscopy (VC). Results: All of the colorectal pathologies could be interactively diagnosed by MPR. On MIP images some pathologies ...

1997-09-01

48

Colour contrast in ballistic gelatine  

British Library Electronic Table of Contents (United Kingdom)

Gelatine is a reliable tissue simulant in wound ballistic experiments. The projectile penetrating the gelatine transfers energy and causes radial cracks according to the temporary cavity. Thus the crack length is a function of the energy spent in the medium. In practice the fissures are poorly contrasted for which reason an enhancement of contrast was searched. A series of six shoots with expanding bullets (9mmx19 Action-5, 9mmx19 Quick Defense 1, 5.56mmx45 Styx Action) was realized on 10% gelatine blocks at 4^oC temperature. Three blocks were marked with acryl paint on the front, three blocks were shot native. The blocks were cut in slices of 1cm thickness and optically scanned. The evaluation was performed according to Fackler's wound profile, the total crack length method and the polygo...

2010-01-01

49

Lacrimal gland masses on CT and MRI: a report of four cases  

International Nuclear Information System (INIS)

In an extended case report, we discuss four cases with masses in the lacrimal fossa representing the most important entities in this region (lymphoma, pleomorphadenoma, inflammatory pseudotumor, and malignant epithelial tumor). The different indications for CT and MRI are explained. For the differential diagnosis of lacrimal gland lesions, the following imaging parameters are important: The shape of the lacrimal gland, the inner structure, the degree of contrast enhancement, and the surrounding bony structures. In the evaluation of the expansion of lacrimal gland lesions, CT in thin slices with multiplanar reconstructions is equal to MRI. However, the contrast-enhancement of lacrimal glands is better evaluated with MRI than with CT. The bony structures are better visualized on CT than on MRI. (orig.).

50

Ewing's sarcoma recurrence vs radiation necrosis in dynamic contrast-enhanced MR imaging: a case report  

International Nuclear Information System (INIS)

Purpose. We report a case of Ewing's sarcoma in the right distal femur in a 6-year-old male to demonstrate how dynamic contrast-enhanced magnetic resonance imaging (DEMRI) findings predicted histopathology. Materials and methods. DEMRI was performed at presentation and during and after completion of chemotherapy and radiation therapy. Histopathologic studies were done at presentation, at 77 weeks (20 weeks after a pathological fracture), and from the en bloc resection at 104 weeks. Results. DEMRI predicted the early tumor response, absence of tumor recurrence, presence of necrosis and lack of fracture healing, confirmed by histopathology. Conclusion. DEMRI is a clinically useful tool in managing Ewing's sarcoma. (orig.)

1999-04-01

51

MR imaging in neuroborreliosis of the cervical spinal cord  

Energy Technology Data Exchange (ETDEWEB)

The central nervous system is involved in 10-20% of cases in Lyme disease. The neurological symptoms, time course of the disease and imaging findings are multifaceted. We report two patients with cervical radiculitis. Magnetic resonance imaging revealed strong enhancement of the cervical nerve roots on contrast-enhanced T1-weighted images. These imaging patterns of borrelia-associated radiculitis have not been reported before. Knowledge of these imaging features may help to diagnose neuroborreliosis, which presents with non-specific symptoms. (orig.)

2004-11-01

52

Coherent correlation enhancement of outer shell photoionization cross sections of alkali-like ions  

Energy Technology Data Exchange (ETDEWEB)

An alkali-like ion interaction with inner electrons of an alkali-like ion leads to a significant increase in the photoionization cross section of the outer s electron. This occurs not only for ground-state ions with one s electron in the outer shell, but also when the outer s electron is in an excited state. The reason for this amplification, in addition to coherent enhancement in summing of the correlation amplitudes, is that the zero in the direct amplitude occurs below threshold. This leads to a constructive interference with the correlation amplitude above the photoionization threshold, in contrast to a destructive interference in the case of a neutral atom with the same electronic configuration, for which the zero occurs above threshold. Results of this research were published.

1995-08-01

53

MR imaging of hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

Magnetic resonance (MR) images of 18 cases of hilar cholangiocarcinoma were evaluated to compare the effectiveness of Gd-DTPA with that of high dose contrast enhancement computed tomography (HCE-CT) in detecting the primary tumor. The primary tumor was demonstrated as having slightly low intensity compared with liver parenchyma and high intensity compared with the delated bile duct on T1-weighted images. In contrast, MRI using Gd-DTPA, which was carried out in five cases, revealed intense enhancement of the tumor. As the differentiation between cholangiocarcinoma and dilated bile duct was difficult, it was concluded that the use of Gd-DTPA improves the efficacy of MRI in diagnosing cholangiocarcinoma. Gd-DTPA was also effective in differentiating the growth pattern of the tumor: the infiltrating type was demonstrated as thickening of the wall of the bile duct, the polypoid type as a soft tissue mass in ...

54

An imaging. gamma. -ray detector with scatter rejection for beam position control in radiotherapy  

Energy Technology Data Exchange (ETDEWEB)

An imaging detector for {gamma}-rays ({approx equal}1 MeV) based on minicell MWPCs with converters and a position resolution of {Delta}x=0.5 mm has been developed and tested. Very high rate capability (>10{sup 8}/cm{sup 2} s) and a special readout for suppression of scattered radiation are implemented allowing to enhance the measured contrast. The relevant physical processes are discussed and first pictures are presented. (orig.).

1991-12-01

55

X-ray phase imaging using a X-ray tube with a small focal spot. Improvement of image quality in mammography  

International Nuclear Information System (INIS)

Phase contrast X-ray imaging has been studied intensively using X-rays from synchrotron radiation and micro-focus X-ray tubes. However, these studies have revealed the difficulty of this technique's application to practical medical imaging. We have created a phase contrast imaging technique using a molybdenum X-ray tube with a small focal spot size for mammography. We identified the radiographic conditions in phase contrast magnification mammography with a screen-film system, where edge effect due to phase contrast overcomes geometrical unsharpness caused by the 0.1 mm-focal spot of a molybdenum X-ray tube. The edge enhancement due to phase imaging was observed in an image of a plastic tube, and then geometrical configuration of the X-ray tube, the object and the screen-film system was determined for phase imaging of mammography. In order to investigate a potential for medical ...

2002-03-01

56

Iodixanol in cerebral computed tomography: a randomized, double-blind, phase-III, parallel study with iodixanol and iohexol  

International Nuclear Information System (INIS)

Iodixanol is a new nonionic dimer, isotonic with blood at all clinically relevant concentrations. Iodixanol (270 mg I/ml) was compared in a double-blind, randomized, parallel-group, phase-III study to the monomeric nonionic iohexol (300 mg I/ml) for evaluation of safety, tolerability and radiographic efficacy during cerebral CT. One hundred adult patients scheduled to undergo contrast-enhanced cerebral CT were randomly allocated to receive either iodixanol or iohexol. All completed the trial. Safety was evaluated by recording discomfort and other adverse events, tolerance by assessing intensity and incidence of discomfort. Radiographic efficacy was assessed from the diagnostic information and the radiographic density. No serious adverse events occurred. One patient (2 %) in the iodixanol group and one patient (2 %) in the iohexol group experienced a transient reddening at the neck and lower neck-line, respectively. Both contrast agents were ...

1999-09-01

57

Real-time neutron radiography for visualisation of interfacial geometry and phase distribution in two-phase flow  

International Nuclear Information System (INIS)

Results of ongoing research project at the McMaster Nuclear Reactor Facility on real-time neutron radiography for the visualization of interfacial geometry, movements and phase distributions in gas-liquid and gas-liquid-metal multi-phase flows are presented. Experiments were conducted with bubble column tubes with boiling liquid nitrogen, air-water and air-mercury mixtures. Discussions are also focused on air-water flowing within a tube containing a CANDU type 37 rod fuel bundle assembly positioned both horizontally and vertically. Computer processing using a digital image format to enhance the real-time images was used. Imaging techniques include frame averaging, background substraction, edge enhancement (spatial filtering), contrast enhancement and video densitometry. (orig.).

1989-10-01

58

Multislice helical CT in the diagnosis of hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

Objective: To investigate the value ofMSCT in observing the direct findings of hilar cholangiocarcinoma1Methods Multislice helical CT studies were performed on the upper abdomen in 19 consecutive patientswith painless jaundice1 Precontrast and dynamic contrast enhanced (25 s phase and 60 s phase) scanswere conducted, and 3D imageswere reconstructed using enhanced raw data in 15 cases1 The direct CT findings of hilar cholangiocarcinoma were studied by three radiologists respectively in a 32scale strategy1 The morphological features and extension of bile duct involvement by hilar cholangiocarcinoma were analyzed1 All the 19 caseswere pathologically p roved as hilar cholangiocarcinoma by surgery (15 cases) and ERCP ( 4 cases) 1 Results The direct findings and extension of hilar cholangiocarcinoma could be demonstrated in 14 out of 15 3D reconstruction images, 8 out of 19 in 25 s phase, and 7 out of 19 in 60 s phase of ...

2005-11-01

59

Enhancing nutrient management through use of isotope techniques  

International Nuclear Information System (INIS)

Enhanced nutrient cycling basically involves close interaction between inorganic and organic sources of nutrients. Contrasting scenarios of nutrient cycling are found under intensive cropping production systems in most industrialized countries and traditional production systems predominant in many developing countries, where there is a net mining of soil nutrients due to crop harvest removal and erosion. Therefore, to enhance nutrient management in marginal tropical soils it is necessary to maximize the efficiency of nutrient uptake from various inorganic and organic sources with minimal environmental impact. It is postulated that one of the main approaches will be the identification and/or selection of plant genotypes for enhanced nutrient acquisition, in particular at low levels of soil available nutrients. In this context, use of various isotope techniques in examining root activity/distribution ...

1994-10-17

60

Peripheral cholangiocarcinoma : three-phase helical CT appearance  

International Nuclear Information System (INIS)

To analyze the enhancement patterns and morphology of peripheral cholangiocar-cinomas (CCs), as seen on three-phase helical CT. Three-phase helical CT scans of 25 cases of 24 patients with pathologically-proven CCs were retrospectively reviewed. After intravenous administration of contrast media, scans of the hepatic arterial phase (HAP) were obtained at 30 seconds, of the portal venous phase (PVP) at 70 seconds, and of the delayed phase (DP) at 3 minutes. Linear, dense, marginal enhancement was seen in 17 CCs (68%), mainly on HAP images (64%) while thick, band-like, peripheral enhancement was seen in 18 (72%), on either PVP (52%) or DP (44%). Internal enhancement was observed in 23 CCs (92%) on PVP (68%) and/or DP (88%), and 19 CCs (76%) among them showed incomplete enhancement of stippled and/or septated patterns. Most (76%) were seen throughout all three ...

1997-08-01

61

Comparison of gadobenate dimeglumine (Gd-BOPTA) with gadopentetate dimeglumine (Gd-DTPA) for enhanced MR imaging of brain and spine tumours in children  

International Nuclear Information System (INIS)

Sixty-three subjects, aged 6 months to 16 years, who were enrolled in a prospective, fully blinded, randomized parallel-group phase III clinical trial, received 0.1 mmol/kg doses of either Gd-BOPTA (n=29) or Gd-DTPA (n=34). The MR images were acquired before and within 10 min of contrast agent injection. The primary objective was to compare the difference from pre-dose to post-dose lesion visualization between Gd-BOPTA and Gd-DTPA. Lesion visualization was determined as the sum of individual scores for three criteria of lesion morphological characteristics (lesion border delineation, internal morphology, and contrast enhancement), each assessed qualitatively using 4-point scales. Quantitative evaluation compared changes in lesion-to-background (LBR) and contrast-to-noise (CNR) ratios and per cent enhancement. Monitoring for adverse events and evaluation of vital signs and laboratory ...

2005-05-01

62

T{sub 1} and T{sub 2} relaxivities of succimer-coated MFe{sub 2}{sup 3+}O{sub 4} (M=Mn{sup 2+}, Fe{sup 2+} and Co{sup 2+}) inverse spinel ferrites for potential use as phase-contrast agents in medical MRI  

Energy Technology Data Exchange (ETDEWEB)

Superparamagnetic MFe{sub 2}{sup 3+}O{sub 4} (M=Mn{sup 2+}, Fe{sup 2+} and Co{sup 2+}) inverse spinel ferrite (ISF) nanoparticles with narrow size distribution having average diameters of 6-8 nm were synthesized by a diol reduction of organic metals and the surface was modified to be hydrophilic by coating with succimer. Magnetic resonance imaging (MRI) contrast enhancement by dipolar coupling defined interactions between the synthesized ISFs and protons in the bulk water was investigated with initial susceptibility, magnetization and anisotropy of the succimer-coated ISFs. The relaxivity ratios, r{sub 2}/r{sub 1}, for MnFe{sub 2}O{sub 4}, Fe{sub 3}O{sub 4} and CoFe{sub 2}O{sub 4} were measured to be 12.2, 23.1 and 62.3, respectively, which demonstrate the potential usefulness of these magnetic nanoparticles as T{sub 2} contrast agents for MRI.

2009-12-15

63

T1 and T2 relaxivities of succimer-coated MFe23+O4 (M=Mn2+, Fe2+ and Co2+) inverse spinel ferrites for potential use as phase-contrast agents in medical MRI  

International Nuclear Information System (INIS)

Superparamagnetic MFe23+O4 (M=Mn2+, Fe2+ and Co2+) inverse spinel ferrite (ISF) nanoparticles with narrow size distribution having average diameters of 6-8 nm were synthesized by a diol reduction of organic metals and the surface was modified to be hydrophilic by coating with succimer. Magnetic resonance imaging (MRI) contrast enhancement by dipolar coupling defined interactions between the synthesized ISFs and protons in the bulk water was investigated with initial susceptibility, magnetization and anisotropy of the succimer-coated ISFs. The relaxivity ratios, r2/r1, for MnFe2O4, Fe3O4 and CoFe2O4 were measured to be 12.2, 23.1 and 62.3, respectively, which demonstrate the potential usefulness of these magnetic nanoparticles as T2 contrast agents for MRI.

2009-12-01

64

Magnified x-ray phase imaging using asymmetric Bragg reflection: Experiment and theory  

International Nuclear Information System (INIS)

X-ray imaging using asymmetric Bragg reflection in the hard x-ray regime opens the way to improve the spatial resolution limit below 1 #mu#m by magnifying the image before detection, simultaneously providing a strong phase contrast. A theoretical formalism of the imaging process is established. Based on this algorithm, numerical simulations are performed and demonstrate that both Fresnel propagation and Bragg diffraction contribute to contrast formation. The achievable resolution of this technique is investigated theoretically; the results obtained can be used to improve future experimental setups. Furthermore, the minimum detectable phase gradient is estimated, for comparison with other phase sensitive imaging techniques. Results from biological objects demonstrate that the technique is viable for imaging both in two and three dimensions. Refraction contrast images are extracted from experimental projection images by an ...

2006-08-01

65

Fluorescence based molecular in vivo imaging; Fluoreszenzgestuetzte molekulare Bildgebung in vivo  

Energy Technology Data Exchange (ETDEWEB)

Molecular imaging represents a modern research area that allows the in vivo study of molecular biological process kinetics using appropriate probes and visualization methods. This methodology may be defined- apart from the contrast media injection - as non-abrasive. In order to reach an in vivo molecular process imaging as accurate as possible the effects of the used probes on the biological should not be too large. The contrast media as important part of the molecular imaging can significantly contribute to the understanding of molecular processes and to the development of tailored diagnostics and therapy. Since more than 15 years PTB is developing optic imaging systems that may be used for fluorescence based visualization of tissue phantoms, small animal models and the localization of tumors and their predecessors, and for the early recognition of inflammatory processes in clinical trials. Cellular changes occur during many diseases, thus the ...

2008-12-15

66

Computed tomography and magnetic resonance imaging of acquired abnormalities of the inner ear and cerebello-pontine angle  

International Nuclear Information System (INIS)

CT and MRI of acquired abnormalities of the inner ear and cerebello-pontine angle present themselves with very typical findings. The imaging should be adapted to the pathology looked for and either CT or MRI should be used alone or in combination.CT, especially high resolution CT (HRCT), provides an excellent bone contrast, while MRI has a much superior soft tissue contrast. Acute inflammatory changes of the inner ear are solely depicted by contrast-enhanced MRI. HRCT excellently depicts osseous changes of the inner ear and cerebellopontine angle such as chronic ossifying labyrinthitis occurring after acute labyrinthitis, otosclerotic or traumatic changes. Tumorous changes not yielding to bony changes are best delineated by MRI. Posttraumatic hemorrhage and chronic fibrotic changes within the labyrinth are depicted by MRI, only. In conclusion HRCT and MRI are excellent methods to delineate acquired abnormalities of the ...

2003-03-01

67

Use of gadolinium as neutron poison in 540 MWe PHWR  

International Nuclear Information System (INIS)

In Pressurised heavy water reactors (PHWRs), neutron poison in the moderator is used to compensate the excess reactivity present in the core on different occasions such as xenon decay during synchronization just after poison out period or start ups from xenon free conditions. It is also used in secondary shutdown system (SDS-2), where required amount of neutron poison is injected directly into the moderator within 2.5 seconds. Further, it is also used for over poisoning the moderator to achieve the guaranteed shutdown state when the regular shutdown systems are taken for maintenance. Generally, two types of moderator poisons are used in power reactors to balance the reactivity of the core and they are boron and gadolinium. Gadolinium is used in the form of gadolinium nitrate (Gd(NO3)3.6H2O). The paper gives the details of estimation of reactivity coefficients of gadolinium for 540 MWe PHWR for different ...

2006-11-13

68

Comparative evaluation of Computed Tomography and Magnetic Resonance Imaging (1.5 T) in the detection of brain metastases  

International Nuclear Information System (INIS)

Forty-four patients with small cell carcinoma of the bronchus underwent CT and MR studies of the brain to detect cerebral metastases. All patients were studied with contrast-enhanced CT scans, short (T1-weighted) and long (T2-weighted), spin-echo (SE) and FLASH 90 grades sequences were also obtained. A quantitative comparison of the results was carried out to assess the sensitivity of the different techniques in the detection of brain metastases according to lesion diameter. Metastases were identified in 19/44 patients (43%). All techniques detected the lesions >2 cm; of the metastases <2 cm, 63/124 (51%) were detected only by GdDTPA SE-T1 and FLASH sequences and 11 more (9%) only by Gd-DTPA SE-T1 scans. All the lesions identified oh enhanced CT scans or on T2-weighted images were easily detected by Gd-DTPA scans. CT sensitivity was higher than that of pre-contrast SE-T1 and FLASH studies and only slightly lower than ...

1991-01-01

69

The crescent and the periluminal halo: Two Computed Tomography signs of aortic aneurysm impending rupture?  

International Nuclear Information System (INIS)

Purpose: To assess the prevalence, significance and practical value of two recently described CT signs of instable aneurysm: the crescent sign and the periluminal halo (a low-attenuating internal layer of the thrombus around the patent lumen). Material and methods: Among the CT examination performed in the last 5 years, they retrospectively selected the nonruptured aneurysms with a diameter exceeding 4 cm (no. = 93 average diameter 5.1 cm, unenhanced images in 28 cases and enhanced in 84) and the ruptured aneurysms (no. = 16, average diameter 6.7 cm, unenhanced images in 9 cases and enhanced in 9). They studied the prevalence of the crescent and halo sing, their relationship with the aneurysm diameter, and the effect of contrast enhancement. Results: The crescent sign was identified with a statistically significant prevalence in ruptured ( 37.5 % or cases) over asymptomatic aneurysms (5.5 %); the halo ...

1997-01-01

70

Poncirin promotes osteoblast differentiation but inhibits adipocyte differentiation in mesenchymal stem cells.  

Science.gov (United States)

Poncirin, flavanone glycoside, isolated from the fruit of Poncirus trifoliata, has anti-bacterial and anti-inflammatory activities. In this study, the effects of poncirin on the differentiation of mesenchymal stem cells were investigated. The C3H10T1/2 mesenchymal stem cells and primary bone marrow mesenchymal stem cells were studied. In the C3H10T1/2 cells, poncirin prevented adipocyte differentiation, as demonstrated by inhibition of cytoplasm lipid droplet accumulation and peroxisome proliferator-activating receptor-? (PPAR-?) and CCAAT-enhancer-binding protein-? (C/EBP-?) mRNA expression. By contrast, poncirin enhanced the expression of the key osteogenic transcription factors, runt-related transcription factor 2 (Runx2) and transcriptional coactivator with PDZ-binding motif (TAZ). Poncirin also enhanced expression of the osteogenic marker genes including alkaline phosphatase (ALP) and osteocalcin ...

2011-05-01

71

MR imaging and MR cholangiopancreatography in the preoperative evaluation of hilar cholangiocarcinoma: correlation with surgical and pathologic findings  

International Nuclear Information System (INIS)

The primary aim was to evaluate delayed contrast-enhanced MRI in depicting perineural spread of hilar cholangiocarcinoma (CCC) and consequently to determine the capability of MRI/MRCP for staging CCC. Fifteen patients that underwent MRI/MRCP and surgical treatment were retrospectively included. Two radiologists evaluated MR images to assess delayed periductal enhancement, extent of bile duct stenosis, liver parenchymal and vascular involvement and presence of liver atrophy. An agreement between delayed enhancement of the bile duct walls and perineural neoplastic spread showed a very good correlation factor (0.93). The overall accuracy in detecting biliary neoplastic invasion was higher for delayed T1-weighted images (93.3%) than for the MRCP images (80%), and T1-delayed image increased the MR accuracy in assessing the neoplastic resectability (p < 0.05). MRI correctly predicted vascular involvement in 73% and liver ...

2008-10-01

72

Diagnostic value of MRI for hepatic hilar cholangiocarcinoma  

International Nuclear Information System (INIS)

Objective: To investigate the value of MRI in the diagnosis of hepatic hilar cholangiocarcinoma. Methods: Sixty-four patients with hepatic hilar cholangiocarcinomas confirmed by surgery or pathology underwent MRI using a 1.5-T superconductive MR system including conventional unenhanced MRI, MRCP and dynamic contrast-enhanced MRI with Gd-DTPA. Results: Dilatation of the intrahepatic biliary tree with narrowing, occlusion or filling defects in the hepatic hilar bile ducts was noted in all 64 cases. Unenhanced MR[ showed T_1- and T_2-hyperintense hilar masses in 42 patients and was normal in the remaining 22 patients. The hilar masses demonstrated slow, progressive and delayed enhancement patterns. There was enhancement of the thickened bile duct wall with luminal narrowing in the 22 patients without hilar masses. Conclusion: The characteristic MRI findings of enhancing hepatic hilar mass and bile duct ...

2010-02-01

73

Dependence of anomalous phosphorus diffusion in silicon on depth position of defects created by ion implantation  

Energy Technology Data Exchange (ETDEWEB)

Transient enhanced diffusion of phosphorus in silicon has been investigated for implants below and above the threshold for a complete amorphization. Rapid thermal processes (electron beam) and conventional furnaces have been used for the annealing. In the case of implants below amorphization, a strong enhanced diffusion, proportional to the amount of damage produced, has been observed. The extent of the phenomenon is practically independent of the damage depth position. In contrast to this, the formation of extended defects at the original amorphous-crystalline interface makes the diffusivity strongly dependent on depth in the case of post-amorphized samples. No enhanced diffusion effect is observed if the dopant is confined in the amorphous layer, while a remarkable increase in the diffusivity is detected for the dopant located in the crystalline region beyond the amorphous-crystalline interface. ...

1989-03-01

74

Imaging findings of abdominal peripheral primitive neuroectodermal tumor: report of four cases with pathological correlation  

British Library Electronic Table of Contents (United Kingdom)

Peripheral primitive neuroectodermal tumors (peripheral PNETs) are rare in the abdomen. We report the imaging findings of four peripheral PNETs arising in the abdomen. Three were ill-demarcated tumors and one was a well-demarcated tumor, with extensive local invasion and lymph node metastasis in two cases, respectively. The tumors are of inhomogeneous attenuation and heterogeneous enhancement after intravenous administration of contrast materials. Although their imaging manifestations cannot distinguish them from other sarcomas, recognition of these imaging features may be helpful in suggesting the possibility of peripheral PNETs in some cases.

2009-01-01

75

IMAGING DIAGNOSIS-SYNOVIAL MYXOMA OF LUMBAR VERTEBRAE ARTICULAR PROCESS JOINT  

British Library Electronic Table of Contents (United Kingdom)

Magnetic resonance (MR) imaging and histopathology were used to diagnose an articular process synovial myxoma in a dog. On MR images, the tumor was characterized by distortion of the left L1-L2 articular process, widening of the articular process joint, and the presence of a mass contiguous with the synovium of the articular process that displaced the spinal cord. The tumor was T2-hyperintense, T1-hypointense, relative to muscle, and had mild contrast enhancement. The MR features of articular process synovial myxoma may be distinct from other diseases of the articular process joint.

2011-01-01

76

Cerebral and meningeal manifestations of AIDS: Sensitivity of CT and T sub 2 -weighted MR (129 patients). Zerebrale und meningeale Manifestation des AIDS: Sensitivitaet von CT und T sub 2 -gewichteter MRT (129 Patienten)  

Energy Technology Data Exchange (ETDEWEB)

We studied 129 AIDS patients with suspected or proved intracranial manifestations of the disease. The purpose of this study was to compare the diagnostic sensitivity of unenhanced and contrast enhanced CT and unenhanced T{sub 2}-weighted MR. Thus, in 20% of our patients MR but not CT was diagnostic. In another 20% MR provided additional diagnostic information. In conclusion, MR is recommended as the imaging modality of choice in AIDS patients with non-conclusive cranial CT. (orig./GDG).

1990-09-01

77

Musicians demonstrate experience-dependent brainstem enhancement of musical scale features within continuously gliding pitch  

British Library Electronic Table of Contents (United Kingdom)

In contrast to language, where pitch patterns consist of continuous and curvilinear contours, musical pitch consists of relatively discrete, stair-stepped sequences of notes. Behavioral and neurophysiological studies suggest that both tone-language and music experience enhance the representation of pitch cues associated with a listener's domain of expertise, e.g., curvilinear pitch in language, discrete scale steps in music. We compared brainstem frequency-following responses (FFRs) of English-speaking musicians (musical pitch experience) and native speakers of Mandarin Chinese (linguistic pitch experience) elicited by rising and falling tonal sweeps that are exemplary of Mandarin tonal contours but uncharacteristic of the pitch patterns typically found in music. In spite of musicians' unf...

2011-01-01

78

MRI findings of the brain in high-voltage electrical burn patient: case report  

Energy Technology Data Exchange (ETDEWEB)

We report the delayed sequelae arising in a case of electrical injury, reviewing the literature on the subject and focusing on the MRI findings of the brain. A 23-year-old male suffered burns to the left parietal scalp, both feet, and the anterior chest wall. Neurological symptoms and MRI abnormalities appeared 14 days after the insult and continued for about three months. T1-weight MR images demonstrated homogeneous hypointensity, while T2-weighted images depicted hyperintense finger-like projections. Contrast-enhanced T1-weighted images demonstrated strong band-like enhancement, indicating meningeal hyperemia. Follow-up MR imaging showed that the lesion had disappeared, indicating that the cerebral edema and meaningeal hyperemia were reversible.

2003-05-01

79

Extraction methods of phase information for X-ray diffraction enhanced imaging  

Energy Technology Data Exchange (ETDEWEB)

X-ray diffraction enhanced imaging (DEI) is one of X-ray phase-contrast imaging methods, which is applied to inspect internal structures of weakly absorbing low-Z samples. The key problem of the DEI is how to extract phase information which is expressed by refraction-angle images from a series of DEI images measured in different positions of the rocking curve of the analyzer. Three effective extraction methods are presented in this paper: the statistical geometric-optics-approximation method, the maximum refraction-angle method and the Gaussian curve fitting method. They are compared with the existing methods, such as the D. Chapman's geometric optics approximation method and the multiple-images statistical method. A 2D computer simulation experiment is performed to draw comparisons of these methods. The experimental results prove that the above three methods have more precision of refraction-angle values than existing methods.

2007-08-21

80

Extraction methods of phase information for X-ray diffraction enhanced imaging  

International Nuclear Information System (INIS)

X-ray diffraction enhanced imaging (DEI) is one of X-ray phase-contrast imaging methods, which is applied to inspect internal structures of weakly absorbing low-Z samples. The key problem of the DEI is how to extract phase information which is expressed by refraction-angle images from a series of DEI images measured in different positions of the rocking curve of the analyzer. Three effective extraction methods are presented in this paper: the statistical geometric-optics-approximation method, the maximum refraction-angle method and the Gaussian curve fitting method. They are compared with the existing methods, such as the D. Chapman's geometric optics approximation method and the multiple-images statistical method. A 2D computer simulation experiment is performed to draw comparisons of these methods. The experimental results prove that the above three methods have more precision of refraction-angle values than existing methods.

2007-08-21

81

Benign lymphoepithelial lesion of the parotid gland in AIDS patients: CT characteristics  

International Nuclear Information System (INIS)

Contrast agent-enhanced CT scans in nine male patients with histologically proved benign lymphoepithelial lesions of the perotid gland were reviewed. All scans showed cystic-appearing masses with peripheral rim enhancement corresponding to the macroscopic appearance of the lesion. Five patients were seropositive for human immunodeficiency virus (HIV) infection or had infections seen in acquired immunodeficiency syndrome. Three patients were members of high-risk groups. Only one patient had symptoms of the SICCA syndrome. Once a rare cause of parotid gland enlargement, benign lymphoepithelial lesions have recently been seen with increasing frequency in patients with HIV infection. Although the CT appearance is not pathognomic, correlation results of aspiration cytology and with clinical history can lead to a preoperative diagnosis of a benign lymphoepithelial lesion.

82

Computerized Tomography versus unenhanced and enhanced fast MRI sequences in the study of liver metastases: Qualitative and quantitative analyses  

International Nuclear Information System (INIS)

The authors compared unenhanced and contrast-enhanced fast MRI and Computerized Tomography in the detection of liver metastases. Eleven patients with single or multiple hepatic lesions (42 in all) were submitted to V and magnetic resonance studies; T1- and T2- weighted TSE, T2-weighted TSE with fat suppression, unenhanced breath-hold TFE and early or delayed enhanced breath-hold TFE images were acquired with a 1.5 T superconductive magnet (Philips NT). The quantitative analysis of all magnetic resonance images was performed for contrast/noise ratio (CNR) and number of detected lesions; magnetic resonance and Computerized Tomography images were also compared qualitatively for lesion conspicuity, anatomical structure identification and artifacts. The results were compared with Student's test. Early enhanced breath-hold TFE was statistically superior to T1-weighted TSE (p = .0009), T2-weighted TSE (p = ...

1997-01-01

83

Visibility of tumor-like details in inline phase contrast mammography using quasimonochromatic X-ray sources  

Energy Technology Data Exchange (ETDEWEB)

A new generation of quasimonochromatic high-flux X-ray sources, based on the X-ray radiation produced through Compton scattering between an electron beam and a laser beam, is under development. One of the possible applications of this source is inline phase contrast mammography, based on the observation of the edge-enhancement effect that can be observed at the border of structures inside the breast in images produced using a partially or totally coherent X-ray beam. In this work we present the results of a set of simulations of inline phase contrast mammography using typical inverse Compton scattering sources parameters. The simulated sample was a tumour-like mass having spherical shape, diameter between 200 {mu}m and 5 mm, placed inside a breast-like matrix, 4 cm thick, and a standard composition of 50% glandular tissue and 50% adipose tissue. We discuss the minimum requirements for mammography using inverse Compton ...

2009-09-01

84

Contrast-enhanced helical CT in sigmoid diverticulitis. Findings and impact on diagnosis and treatment; Ruolo della tomografia computerizzata spirale nella diverticolite del sigma e implicazioni diagnostico-terapeutiche  

Energy Technology Data Exchange (ETDEWEB)

Aim of this retrospective study was to assess the capability of contrast-enhanced helical computerised tomography (CT) in sigmoid diverticulitis, especially relative to selection of the appropriate treatment. The findings of 41 patients were reviewed from 1998 to 1999 June. Contrast-enhanced helical CT is the imaging modality of choice in assessing mild or severe acute diverticulitis because it provides useful information for appropriate treatment planning in the emergency setting. This technique is most useful in questionable cases and in patients with suspected severe diverticulitis where a choice must be made between different treatment options. [Italian] Scopo di questo studio retrospettivo e' illustrare i molteplici aspetti radiologici della flogosi diverticolare sigmoidea con tomografia computerizzata (TC) spirale, con specifico riguardo alle implicazioni terapeutiche che scaturiscono dall'analisi e dal confronto dei ...

2000-03-01

85

Value of contrast-enhanced MRI of breast after silicone implant; Wertigkeit der Kontrastmittelmagnetresonanztomographie der Mamma bei Wiederaufbau mittels Implantat  

Energy Technology Data Exchange (ETDEWEB)

Early recognition of recurrence and work-up of clinically indeterminate lesions may be impaired after reconstruction with silicone implants due to superimposition of the implant or to scarring. This study was undertaken to evaluate the use of contrast-enhanced MRI in patients with silicone implant after breast cancer. Contrast-enhanded MRI was offered to 169 patients. Comparative two- to three-view mammography was also performed in 169 patients, as well as comparative sonography in 144 patients. Conventional imaging and clinical examination detected only 8/13 recurrences, whereas 12/13 were detected by MRI. One recurrence had been visible as a strongly enhancing 2-mm dot in a previous examination (2 years before), but was not called. It was therefore counted as false negative. In addition, multicentricity was detected by MRI alone in two of three cases. MRI correctly diagnosed scar tissue in all cases with indeterminate ...

1997-09-01

86

Study of the Photon Strength Functions for Gadolinium Isotopes with the DANCE Array  

Science.gov (United States)

The gadolinium isotopes are interesting for reactor applications as well as for medicine and astrophysics. The gadolinium isotopes have some of the largest neutron capture cross sections. As a consequence they are used in the control rod in reactor fuel assembly. From the basic science point of view, there are seven stable isotopes of gadolinium with varying degrees of deformation. Therefore they provide a good testing ground for the study of deformation dependent structure such as the scissors mode. Decay gamma rays following neutron capture on Gd isotopes are detected by the DANCE array, which is located at flight path 14 at the Lujan Neutron Scattering Center at Los Alamos National Laboratory. The high segmentation and close packing of the detector array enable gamma-ray multiplicity measurements. The calorimetric properties of the DANCE array coupled with the neutron time-of-flight technique enables one to gate on a ...

2009-03-10

87

Near Infrared-Fluorescent and Magnetic Resonance Imaging Molecular Probe with High T1 Relaxivity for In Vivo Multimodal Imaging  

UK PubMed Central (United Kingdom)

A new gadolinium chelating NIR fluorescent molecular probe increases T1 relaxivity of water protons, facilitating combined optical and magnetic resonance imaging.

2010-06-07

88

Gadolinium-containing phosphatidylserine liposomes for molecular imaging of atherosclerosis  

UK PubMed Central (United Kingdom)

Exteriorized phosphatidylserine (PS) residues in apoptotic cells trigger rapid phagocytosis by macrophage scavenger receptor pathways. Mimicking apoptosis with liposomes containing PS may represent...Full Text Available

2009-11-01

89

Dislocation-enhanced hydrogen solubilities in Pd-Ni, Pd-Ag and Pd-Ni-Ag alloys  

Science.gov (United States)

The purpose of this communication is to determine whether the solubility enhancements for cold-worked Pd-Ni alloys increase or decrease with atom fraction of Ni. Substitutional Ni atoms contract and Pd lattice, in contrast to the lattice expansion resulting from substitutional Ag in Pd. The Pd-Ni alloy system forms a continuous series of fcc solid solution alloys over the whole composition range. The solubility enhancements will also be determined for a series of homogeneous, ternary Pd[sub 1[minus]x]Ni[sub 1/2x]Ag[sub 1/2x] alloys for x in the range from 0 to 0.2. For this series of ternary alloys the fcc lattice parameters do not change significantly from that of pure Pd. The alloys used in this research were purchased from Tanaka Kikinzoku Kogyo K.K. The detailed experimental procedure has been described previously. The alloys were all deformed by cold-rolling ca 90%. Both the binary and ternary alloys showed only single ...

1994-03-01

90

Analysis and calibration of transient enhanced diffusion for an indium impurity in a nanoscale semiconductor device  

Energy Technology Data Exchange (ETDEWEB)

We developed a new systematic calibration procedure which was applied to the prediction of the diffusivity, the segregation, and transient enhanced diffusion (TED) of an indium impurity. The TED of the indium impurity was studied using four different experimental conditions. Although indium is susceptible to TED, rapid thermal annealing (RTA) is effective in suppressing the TED effect and maintaining a steep retrograde profile. Like boron impurities, the indium shows significant oxidation-enhanced diffusion in silicon and has segregation coefficients much less than 1 at the Si/SiO{sub 2} interface. In contrast to boron, the segregation coefficient of indium decreases as the temperature increases. The accuracy of the proposed procedure was validated by using secondary ion mass spectrometry (SIMS) data and by using the 0.13-{mu}m device characteristics, such as V{sub th} and I{sub dsat}, for which the differences between ...

2005-02-15

91

Analysis and calibration of transient enhanced diffusion for an indium impurity in a nanoscale semiconductor device  

International Nuclear Information System (INIS)

We developed a new systematic calibration procedure which was applied to the prediction of the diffusivity, the segregation, and transient enhanced diffusion (TED) of an indium impurity. The TED of the indium impurity was studied using four different experimental conditions. Although indium is susceptible to TED, rapid thermal annealing (RTA) is effective in suppressing the TED effect and maintaining a steep retrograde profile. Like boron impurities, the indium shows significant oxidation-enhanced diffusion in silicon and has segregation coefficients much less than 1 at the Si/SiO_2 interface. In contrast to boron, the segregation coefficient of indium decreases as the temperature increases. The accuracy of the proposed procedure was validated by using secondary ion mass spectrometry (SIMS) data and by using the 0.13-#mu#m device characteristics, such as V_t_h and I_d_s_a_t, for which the differences between simulation and ...

2005-02-01

92

Neutron-computer tomography using real-time neutron radiography  

Energy Technology Data Exchange (ETDEWEB)

A real-time neutron radiography facility was constructed including the capability of neutron tomography. The neutron beam was measured for total neutron flux ((1.0 +/- 0.2) x 10/sup 11/ m/(m/sup 2/-sec)), gold cadmium ratio (52 +/- 3) and effective neutron temperature (83/sup 0/C +/- 8/sup 0/C). The angular divergence or nonparallelism of the neutron beam was measured to be 2.3/sup 0/ +/- 0.1/sup 0/ thereby providing a means of quantifying the collimator effectiveness. The resolution capabilities of both static film and real-time neutron radiographs were quantified using a Fourier transform algorithm to calculate the modulation transfer function of both types of radiographs. The contrast sensitivity of both types of radiographs. The contrast sensitivity of both types of radiographs was measured as 3.1% for film and 4.0% for real-time radiographs. Two tomography algorithms, the simultaneous iterative reconstruction technique (SIRT) and the ...

1986-01-01

93

Neutron-computer tomography using real-time neutron radiography  

International Nuclear Information System (INIS)

A real-time neutron radiography facility was constructed including the capability of neutron tomography. The neutron beam was measured for total neutron flux ((1.0 +/- 0.2) x 10"1"1 m/(m"2-sec)), gold cadmium ratio (52 +/- 3) and effective neutron temperature (83"0C +/- 8"0C). The angular divergence or nonparallelism of the neutron beam was measured to be 2.3"0 +/- 0.1"0 thereby providing a means of quantifying the collimator effectiveness. The resolution capabilities of both static film and real-time neutron radiographs were quantified using a Fourier transform algorithm to calculate the modulation transfer function of both types of radiographs. The contrast sensitivity of both types of radiographs. The contrast sensitivity of both types of radiographs was measured as 3.1% for film and 4.0% for real-time radiographs. Two tomography algorithms, the simultaneous iterative reconstruction technique (SIRT) and the convolution method, were ...

1986-01-01

94

Iodixanol in cerebral computed tomography: a randomized, double-blind, phase-III, parallel study with iodixanol and iohexol  

Energy Technology Data Exchange (ETDEWEB)

Iodixanol is a new nonionic dimer, isotonic with blood at all clinically relevant concentrations. Iodixanol (270 mg I/ml) was compared in a double-blind, randomized, parallel-group, phase-III study to the monomeric nonionic iohexol (300 mg I/ml) for evaluation of safety, tolerability and radiographic efficacy during cerebral CT. One hundred adult patients scheduled to undergo contrast-enhanced cerebral CT were randomly allocated to receive either iodixanol or iohexol. All completed the trial. Safety was evaluated by recording discomfort and other adverse events, tolerance by assessing intensity and incidence of discomfort. Radiographic efficacy was assessed from the diagnostic information and the radiographic density. No serious adverse events occurred. One patient (2 %) in the iodixanol group and one patient (2 %) in the iohexol group experienced a transient reddening at the neck and lower neck-line, respectively. Both contrast agents were ...

1999-09-01

95

Modern imaging methods for diagnostic evaluation of tumors of the oropharynx and the oral cavity  

International Nuclear Information System (INIS)

Differentiating a benign from a malignant lesion by information such as density data, or signal intensities or echo gradients, is not possible with CT, nor MRI, nor ultrasonography. Only some lesions show characteristic signs. Inflammations cannot be difscriminated from malignant tumors. CTs of small tumors in particular are so poor in contrast that it is much more difficult to detect tumors or discriminate them from other lesions, as compared to MR images or ultrasonographs. CT does not detect surface tumors, but is more sensitive than MRI or US in detecting discrete cortical bone lesions. The same applies to small calcified tumors. MRI however is most sensitive in detecting tumor volumes in the yellow marrow, and is the best modality for evaluation of extraossal extension of tumors. CT yields better results than MRI if applied for simultaneous screening of lymph node metastases in the lower neck. MRI frequently is spoilt by movement artefacts. High-resolution, ...

96

Magnetic resonance imaging in acute intractional tuberculosis; Magnetresonanztomographie bei akuter intrakranieller Tuberkulose  

Energy Technology Data Exchange (ETDEWEB)

We reported three cases of acute intracranial tuberculosis including miliary tuberculosis, basal meningitis, tuberculomas and neuritis of cranial nerves. All patients had native and contrast enhanced CT and MRI scans. MRI revealed more granulomas and a better imaging contrast in the detection of basal meningitis. Neuritis was diagnosed only with the MRI. MRI scans should be prefered as the imaging procedure in clinically presumed intracranial tuberculosis. (orig.) [Deutsch] Die Befunde von drei Patienten mit intrakranieller Tuberkulose (intrakranielle Miliartuberkulose, Meningitis tuberculosa, Neuritis und Tuberkulome) in der Magnetresonanztomographie (MRT) wurden mit der Computertomographie (CT) verglichen. Sowohl die MRT als auch die CT wurden nativ und nach Kontrastmittelgabe durchgefuehrt. Die MRT zeigte sich im Nachweis von Granulomen insbesondere im Bereich des Hirnstamms ueberlegen. Ebenso wurde ein hoeherer ...

1994-12-31

97

MRI in pleural diseases  

International Nuclear Information System (INIS)

The MRI and CT appearances in 48 patients with histologically confirmed benign and malignant pleural abnormalities were compared retrospectively. Abnormal pleural changes were shown in 47 out of the 48 patients by high signal intensity of the pleura in T_2-weighted sequences and in contrast enhanced T_1-weighted sequences on MRI. CT showed abnormalities in 45 out of 48 patients. Delineation of pleural and pulmonary changes by CT was possible in 13 out of 23 cases, and pleural disease from effusions in 15 out of 28 cases. T_2-weighted MRI was successful in 14 out of 23 and 4 out of 28 cases, respectively. T_1-weighted images after contrast were successful in 20 out of 23 and 22 out of 28 cases, respectively. Indications of malignant pleural disease were the presence of mediastinal or circumferential involvement or involvement of the entire pleura, thickness of more than 10 mm and nodular changes. The most reliable sign of ...

98

Influence of contrast-enhanced CT and MRI with or without SPIO particles on therapy and therapy costs for patients with focal liver disease  

International Nuclear Information System (INIS)

Purpose: Evaluation of the diagnostic efficacy and cost-benefit of contrast enhanced CT (CT) and MRI pre- and post-SPIO-particles in focal hepatic disease with consideration of therapeutic outcome. Results: In 34/52 (65.4%) of the cases the correct diagnosis was primarily stated by CT (sensitivity [se.] 85.2%, specificity [sp.] 44.0%). In additional 10/52 of the cases unenhanced MRI (se. 91.4%, sp. 75.0%) enabled correct diagnoses, and in another 6 cases the diagnosis was established only by SPIO-MRI (se. 100%, sp. 86.7%). Considering the possible therapeutic recommendation arising from each modality, CT would have induced needless therapy costs of 191,042 DM, unenhanced MRI of 171,035 DM, and SPIO-MRI of 7,311 DM. In comparison to the real therapy costs of 221,873 DM, this would have corresponded to an unnecessary increase of therapy costs of 86.1%, 77.1%, and 3.3%, respectively. In two cases (91 hemangioma, 1 regenerative nodule) all ...

2000-03-01

99

Dual energy virtual CT colonoscopy with dual source computed tomography. Initial experience  

International Nuclear Information System (INIS)

Purpose: To describe the technique of DE MDCT colonoscopy and to assess its feasibility. Materials and Methods: 8 patients were scanned with DSCT with a DE scan protocol and dose modulation software. Analysis was performed using dedicated DE software. Prone non-contrast images and DE supine images after contrast injection were obtained. Results: DE colonoscopic images were successfully obtained in 7 patients, but the FOV did not cover all colonic segments in 1 patient, thus resulting in a technical success rate was 87.5%. Streak artifacts were present in the pelvic region in 2 patients. Virtual unenhanced images and iodine map images were obtained for all patients. In 1 patient a polypoid non-enhancing structure was noted on the iodine map, and conventional colonoscopy revealed impacted stool. Enhancing rectal cancer in 1 patient was correctly shown on the iodine map. Iodine maps helped to differentiate ...

2009-09-01

100

Multiphasic helical CT of hepatocellular carcinoma. Evaluation after chemo embolization  

International Nuclear Information System (INIS)

The main purpose of this work is to report the personal experience with addition of contrast-enhanced multiphase helical CT to unenhanced CT (Lipiodol CT) in the evaluation of patients with hepatocellular carcinoma treated with chemoembolization and to analyze the present role of oily agent CT. It has been retrospectively reviewed the examinations of 42 consecutive patients submitted to globla chemoembolization over a 2-year period. CT was performed 18-30 days after the treatment. The Lipiodol CT study was carried out with volume acquisitions. It has been considered as nodules all well-defined areas with dense oily agent uptake; uptake itself was classified as: 0=absent, I=lower tha 10% of the tumor volume; II=lower than 50%, III=50%, IV=homogeneous. Contrast-enhanced helical CT was performed with the 2-phase technique in 28 patients and with the 3-phase technique in 14; it has been considered as nodules all well-defined and relatively ...

2000-06-01

101

Tin doping in spray pyrolysed indium sulfide thin films for solar cell applications  

British Library Electronic Table of Contents (United Kingdom)

This paper presents studies carried out on tin-doped indium sulfide films prepared using Chemical Spray Pyrolysis (CSP) technique. Effect of both in-situ and ex-situ doping were analyzed. Ex-situ doping was done by thermal diffusion, which was realized by annealing Sn/In2S3 bilayer films. In-situ doping was accomplished by introducing Sn into the spray solution by using SnCl45H2O. Interestingly, it was noted that by ex-situ doping, conductivity of the sample enhanced considerably without affecting any of the physical properties such as crystallinity or band gap. Analysis also showed that higher percentage of doping resulted in samples with low crystallinity and negative photosensitivity. In-situ doping resulted in amorphous films. In contrast to ex-situ doping, `in- situ doping' resulted i...

2010-01-01

102

The effect of V and W addition on the high temperature strength properties of 12%Cr-15%Mn austenitic steels  

International Nuclear Information System (INIS)

The effect of W and V on the high temperature strength properties of 12%Cr-15%Mn austenitic steels was studied from the view point of precipitation hardening and internal stress. The contribution of W addition to the tensile and creep-rupture strength was not so large. By contrast the combined addition of W and V increased the strength considerably. These are resulted from the precipitation of fine vanadium nitride (VN) within grains and the enhancement of M_2_3C_6 type carbide precipitation at grain boundaries. The V added material had large internal stress value which is considered to be due to dislocation movement disturbed by fine vanadium nitrides. (author).

103

The comparative effects of oil dispersants and oil/dispersant conjugates on germination of the marine macroalga Phyllospora comosa (Fucales: Phaeophyta)  

Energy Technology Data Exchange (ETDEWEB)

Germination inhibition of the marine macrophyte Phyllospora comosa was utilized as a sub-lethal end-point to assess and compare the effects of four oil dispersants and dispersed diesel fuel and crude oil combinations. Inhibition of germination by the water-soluble fraction of diesel fuel increased following the addition of each of the dispersants; the nominal 48-h EC{sub 50} concentration of diesel fuel declined from 6800 to approximately 400 {mu}l 1{sup -1} nominal for each dispersed combination. This contrasted with crude oil, where the addition of two dispersants resulted in an enhanced germination rate and an increase in nominal EC{sub 50} concentrations from 130 {mu}l 1{sup -1} for the undispersed crude to 4000 and 2500 {mu}l 1{sup -1}. The results indicate that, while germination inhibition of P. comosa may be enhanced by the chemical dispersal of oil response varies with type of both oil and oil dispersant. (author)

1995-04-01

104

MR imaging of experimental intramuscular hemorrhage at 0. 02 T; Contrast enhancement with Gd-DOTA  

Energy Technology Data Exchange (ETDEWEB)

Intramuscular hermorrhage was induced by injecting autologous blood into the paraspinal muscle of 8 rabbits. In order to evaluate the time-dependent changes of hemorrhage observed on MRI, the animals were imaged at different stages of blood resolution at 0.02 tesla (T), and control examined with ultrasound using a 7.5 MHz linear transducer. Six inversion recovery sequences (TR=1 000 ms. TE=30 ms, and TI=18, 48, 148, 201, 302, and 398 ms) were used for the invivo calculation of T1 relaxation times. IR 1 000 (398)/30 imaging was performed before and after the Gd-DOTA administration. The hemorrhage was evident on MR images throughout the study, especially on the T2 weighted (SE 1 000/100) images. MRI showed the healing lesion longer than ultrasound. The T1 relaxation time increased during the time of resolution. Lesions on days 4 to 7 enhanced in intensity after the injection of Gd-DOTA. (orig.).

1990-09-01

105

Longitudinal impedance and wake from XFEL undulators. Impact on current-enhanced SASE schemes  

Energy Technology Data Exchange (ETDEWEB)

In this article we derive longitudinal impedance and wake function for an undulator setup with arbitrary undulator parameter, taking into account a finite transverse size of the electron bunch. Earlier studies considered a line density-distribution of electrons instead. We focus our attention on the long-wavelength asymptote (compared with resonance wavelength), at large distance of the electron bunch from the undulator entrance compared to the overtaking length, and for large vacuumchamber size compared to the typical transverse size of the field. These restrictions define a parameter region of interest for practical applications. We calculate a closed expression for impedance and wake function that may be evaluated numerically in the most general case. Such expression allows us to derive an analytical solution for a Gaussian transverse and longitudinal bunch shape. Finally, we study the feasibility of current-enhanced SASE schemes (ESASE) recently proposed for ...

2007-06-15

106

Efficacy of MR mammography (MRM) in providing preoperative locoregional information on breast cancer. Correlation between MRM and histological findings  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study was to assess the efficacy of MRM in providing preoperative locoregional information on patients with breast cancer. MRI was performed on 62 female breast cancer patients. A 1.5 T MR-system was used to acquire fat-suppressed T{sub 1}WI, T{sub 2}WI and dynamic-contrast-enhanced images with an SPGR pulse sequence. The extent of the cancer measured with MRM was confirmed histologically in all patients. The size obtained from MRM correlated well with the size obtained histologically, including intraductal spread of cancer (R: 0.853). As for shape, the round/oval type evident from MRM correlated more accurately (R: 0.934) than the ill-defined type associated with a linear and/or clumped enhanced area (R:0.744). The difference between the size obtained from MRM and the size obtained histologically, including IDS, was less than 15 mm in the majority of patients (93.5%). MRM accurately reveals the extent of cancer, including ...

2002-07-01

107

Cholangiocarcinoma associated with recurrent pyogenic cholangitis: sonographic and CT findings  

International Nuclear Information System (INIS)

Cholangiocarcinoma may be associated with recurrent pyogenic cholangitis as a complication of longstanding proliferative cholangitis in the presence of intrahepatic stones. Sonographic and CT findings of six patients with cholangiocarcinoma of the liver associated with recurrent pyogenic cholangitis are presented. The cases were among 128 patients who underwent partial resection of the liver because of recurrent pyogenic cholangitis and its complication. On sonogram the mass was depicted in four patients as an ill-defined heterogenously echogenic mass and in one patient as a bulging contour; in the remaining one case the mass was not detected. There were small or large, shadowing or non shadowing stones within the tumor in five cases. In one case, the stone was in the duct proximal to the tumor. On CT scans of four patients, the tumors were depicted as an ill-defined, irregular low attenuation masses with variable contrast enhancement, the ...

1992-01-01

108

Synthesis and photoluminescence properties of Sm3+-doped LaMgB5O10 and GdMgB5O10  

International Nuclear Information System (INIS)

Luminescence and reflection spectra as well as luminescence kinetics of the 1 mol% Sm3+-doped crystalline lanthanum magnesium meta borate (LaMgB5O10) and gadolinium magnesium meta borate (GdMgB5O10) were analyzed. Materials were synthesized by conventional solid state route and showed bright orange-red emission under UV excitation. Emission spectra contain sharp and well resolved Sm3+4G5/2#->#6HJ transitions indicating a strong crystal-field effect. In case of gadolinium compound energy transfer between Gd3+ and Sm3+ was detected. The luminescent kinetics of the Sm3+ in analyzed powders is characterized by single exponential decay and experimental values vary in the range 2.2-2.4 ms. - Research highlights: ? Phosphorescence of samarium-doped lanthanide magnesium meta borates. ? Bright and well resolved orange-red emission of Sm3+ under UV excitation. ? Energy transfer from Gd3+ to Sm3+ in gadolinium magnesium meta borate ...

2011-07-01

109

The new WHO classification of brain tumors. Radiological aspects of 4 new tumor entities; Die revidierte WHO-Klassifikation der Hirntumoren. Radiologische Aspekte unter besonderer Beruecksichtigung von vier neuen Tumorentitaeten  

Energy Technology Data Exchange (ETDEWEB)

Characterisation of the classification of brain tumours authorised by the WHO. Method of appraisal: This classification was revised and published in its second version. In the revision, some tumours were regrouped histogenetically and some tumour variants were added. Radiologically relevant changes of the classification include the differentiation of four new tumour entities that are easily distinguished by MR imaging. These four tumours belong to the group of childhood tumours or tumours occurring in early adulthood and are characterized by a good prognosis after extirpation. Results of appraisal: Central neurocytomas are small-cyst ventricular tumours associated with the foramen of Monroi and show moderate contrast enhancement. Infantile desmoplastic gangliogliomas/astrocytomas commonly consist of a solid tumour portion related to the leptomeninges with pronounced contrast enhancement and a typically ...

1997-06-01

110

Spectroscopy of gadolinium gallium garnet crystals doped with Y b3+ revisited  

International Nuclear Information System (INIS)

The optical spectroscopy measurements of gadolinium gallium garnet (GGG) crystals doped with Yb show evidence of the presence of non-equivalent optical centers with very similar radiative decay rates. The energy level schemes of those centers have been determined on the basis of optical absorption, luminescence and Raman experiments. Crystal field fitting resulted in two sets of slightly different crystal field parameters for two non-equivalent Yb centers. Both sets of parameters describe perfectly the experimentally detected Y b3+ energy levels. Correlation between systematic trends in the experimental energy level schemes and crystal field parameters is discussed.

2010-06-30

111

Gadolinium (III) chelates of O, N-donor Schiff bases derived from 2, 3-dimethyl-4-formyl-1-phenyl-3-pyrazoline-5-one and certain aromatic amines  

International Nuclear Information System (INIS)

New Schiff base chelating ligands were synthesized by reacting equimolar quantities of 2,3-dimethyl-4-formyl-1-phenyl-3-pyrazoline-5-one and o-anisidine, p-anisidine, m-anisidine, o-toluidine, p-toluidine, m-toluidine, 2,6-xylidine or 2,4-xylidine in ethanol medium. Their subsequent reaction with gadolinium (III) nitrate hexahydrate in 2:1 molar ratio gave complexes that were characterized by elemental analyses, molar conductances, magnetic measurements, electronic and I.R. spectral studies. All the chelates were found to be non-electrolytic in nature. (author). 15 refs., 1 fig., 1 tab.

1994-01-01

112

Thoracic aortic stent graft: comparison of contrast-enhanced MR angiography and CT angiography in the follow-up: initial results  

Energy Technology Data Exchange (ETDEWEB)

The objective of this study was to compare contrast-enhanced magnetic resonance angiography (CE MRA) and multislice computed tomographic angiography (MS CTA) in the follow-up of thoracic stent-graft placement. The CE MRA and MS CTA were performed following nitinol stent-graft treatment due to thoracic aneurysm (n=4), intramural bleeding (n=2) and type-B aortic dissection (n=5). Corresponding evaluation of arterial-phase imaging characteristics focused on the stent-graft morphology and leakage assessment. Stent-graft and aneurysm extensions were comparable between both techniques. Complete exclusion (aneurysm, n=4; dissection, n=2) was assessed with high confidence with CE MRA and MS CTA. Incomplete exclusion (intramural bleeding, n=2; dissection, n=3) was assigned to lower confidence scores on CE MRA compared with MS CTA. On CE MRA the stent-graft lumen demonstrated an inhomogeneous signal, the stent struts could not be assessed. The CE MRA can be used as ...

2003-07-01

113

Lacrimal gland masses on CT and MRI: a report of four cases; Raumforderungen der Traenendruese in CT und MRT am Beispiel von vier Faellen  

Energy Technology Data Exchange (ETDEWEB)

In an extended case report, we discuss four cases with masses in the lacrimal fossa representing the most important entities in this region (lymphoma, pleomorphadenoma, inflammatory pseudotumor, and malignant epithelial tumor). The different indications for CT and MRI are explained. For the differential diagnosis of lacrimal gland lesions, the following imaging parameters are important: The shape of the lacrimal gland, the inner structure, the degree of contrast enhancement, and the surrounding bony structures. In the evaluation of the expansion of lacrimal gland lesions, CT in thin slices with multiplanar reconstructions is equal to MRI. However, the contrast-enhancement of lacrimal glands is better evaluated with MRI than with CT. The bony structures are better visualized on CT than on MRI. (orig.) [Deutsch] In einem erweiterten Fallbericht wird ueber die vier grossen Entitaeten bei Traenendruesenraumforderungen berichtet ...

1995-11-01

114

Multi-modality imaging of uveal melanomas using combined PET/CT, high-resolution PET and MR imaging  

Energy Technology Data Exchange (ETDEWEB)

We investigated the efficacy of combined FDG-PET/CT imaging for the diagnosis of small-size uveal melanomas and the feasibility of combining separate, high-resolution (HR) FDG-PET with MRI for its improved localization and detection. Patients, methods: 3 patients with small-size uveal melanomas (0.2-1.5 ml) were imaged on a combined whole-body PET/CT, a HR brain-PET, and a 1.5 T MRI. Static, contrast-enhanced FDG-PET/CT imaging was performed of head and torso with CT contrast enhancement. HR PET imaging was performed in dynamic mode 0-180 min post-injection of FDG. MRI imaging was performed using a high-resolution small-loop-coil placed over the eye in question with T2-3D-TSE and T1-3D-SE with 18 ml Gd-contrast. Patients had their eyes shaded during the scans. Lesion visibility on high-resolution FDGPET images was graded for confidence: 1: none, 2: suggestive, 3: clear. Mean tumour activity was ...

2008-07-01

115

Aortic non communicating dissections. A study with helical CT  

International Nuclear Information System (INIS)

The evaluate the signs of aortic intramural hematoma with helical CT and the diagnostic role of this technique in patients with this condition. It was reviewed the CT findings of 396 patients submitted to emergency examinations for suspected aortic dissection from 1995 to 1999. Only 18 patients (6 women and 12 men) had CT signs of aortic intramural hematoma. Helical CT studies were carried out with the following parameters: slice thickness 10 mm, reconstruction index 10, feed 1.5 mm, conventional algorithm with minimum values of 130 kV and 125mA. All patients were examined with dynamic contrast-enhanced CT, before and after a power injection of 130 mL ionic contrast material. It was studied: hematoma localization and longitudinal extension; thickness and density of aortic wall; presence and location of intimal calcifications; integrity of intimal wall; hemo mediastinum and/or hemo thorax. Aortic wall thickening appeared as a high density ...

2000-09-01

116

The crescent and the periluminal halo: Two Computed Tomography signs of aortic aneurysm impending rupture?; La semiluna e l`alone periluminale: Due segni con Tomografia Computerizzata di aneurisma aortico a rischio di rottura?  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To assess the prevalence, significance and practical value of two recently described CT signs of instable aneurysm: the crescent sign and the periluminal halo (a low-attenuating internal layer of the thrombus around the patent lumen). Material and methods: Among the CT examination performed in the last 5 years, they retrospectively selected the nonruptured aneurysms with a diameter exceeding 4 cm (no. = 93 average diameter 5.1 cm, unenhanced images in 28 cases and enhanced in 84) and the ruptured aneurysms (no. = 16, average diameter 6.7 cm, unenhanced images in 9 cases and enhanced in 9). They studied the prevalence of the crescent and halo sing, their relationship with the aneurysm diameter, and the effect of contrast enhancement. Results: The crescent sign was identified with a statistically significant prevalence in ruptured ( 37.5 % or cases) over asymptomatic aneurysms (5.5 %); the halo ...

1997-04-01

117

Primary malignant lymphoma of the brain; Primaere maligne Lymphome des Gehirns  

Energy Technology Data Exchange (ETDEWEB)

Primary malignant lymphoma of the brain is a disease of unknown etiology, which is increasing in incidence and has an unfavorable prognosis. Despite the lack of specific changes on CT or MRI in most cases, these procedures may typically facilitate the diagnosis: A focal-enhancing mass with subependymal spread on CT or MRI and hyperattenuation on nonenhanced CT are the most reliable features in the diagnosis of primary malignant lymphoma of the brain. Peritumoral edema and mass effect are usually not prominent features. On unenhanced CT scans they usually appear homogeneously isodense to mildly hyperdense relative to the gray matter. On MRI these tumors are slightly hypointense on T1-weighted images and slightly hpyerintense on PD- and T2-weighted images relative to the gray matter. On CT and MRI enhancement is usually homogeneous. Contrast-enhanced MRI, with its multiplanar capability, lack of bone-induced artifacts, and ...

1997-01-01

118

Ion-exchange scheme for selective removal of gadolinium nitrate from the moderator system of 540 MWe Indian PHWRs using macroporous strong acid cation and macro porous weak base anion resins  

International Nuclear Information System (INIS)

Gadolinium nitrate has been employed in Indian nuclear reactors for the first time as soluble neutron poison in the heavy water moderators of the 540 MWe PHWRs TAPS 3 and 4, as a fast acting secondary shut down system (SDS-2); and also for reactivity shim. For this purpose, the moderator purification system is currently equipped with special ion-exchange columns/schemes, developed by present authors. However, for gadolinium removal from moderator in the post SDS-2 scenario, the two stage ion-exchange - cation bed operation followed by mixed bed operation - results in low pH conditions persisting in the moderator for a few hours, which gives rise to certain operational problems. The present paper describes a mixed bed ion-exchange scheme employing macro-porous strong acid cation and macro-porous weak base anion resins, which has been developed to eliminate acidic conditions and gives a better pH control. The cation to anion capacity ratio in the ...

2008-12-01

119

Current diagnosis of tumors developed in the internal auditory canal and cerebellopontine angle  

Energy Technology Data Exchange (ETDEWEB)

The introduction of CT scan and, more recently, magnetic resonance imaging, has radically changed the diagnostic approach to tumors developed in the internal auditory canal and cerebellopontine angle. CT scan with intravenous injection visualizes tumors lying in the cerebellopontine angle. Magnetic resonance imaging, especially using gadolinium, is a very accurate means for diagnosing tumors of both the auditory canal and cerebellopontine angle.

1988-10-13

120

Sodium bicarbonate-based hydration prevents contrast-induced nephropathy: a meta-analysis  

UK PubMed Central (United Kingdom)

BackgroundContrast-induced nephropathy is the leading cause of in-hospital acute renal failure. This side effect of contrast agents leads to increased morbidity, mortality, and health...Full Text Available

121

Role of early phase helical CT images in the evaluation of wall invasion of colorectal cancer. Pathological correlation  

Energy Technology Data Exchange (ETDEWEB)

The usefulness of helical CT early phase images optimized by the SmartPrep method for evaluation of wall invasion by colorectal cancer was investigated. Between August 1997 and September 1998, CT was performed to evaluate the primary tumor and local extension in 10 consecutive patients with colorectal cancer confirmed by barium enema- and/or colonoscopy. Early-phase images were acquired by using SmartPrep application software. This method allows the optimal scan delay time to be obtained by continuous monitoring of increases in CT values after injection of contrast medium. Sections of the surgical specimens, close to the same plane as the CT images, and of the same slice thickness, were analyzed histopathologically. All 10 cancers, regardless of size, showed strong enhancement on the early-phase images (81.4-112 HU, mean: 95.1 HU). The strongly enhanced image areas on CT corresponded to the primary cancer areas on ...

2000-02-01

122

Comparison of contrast-enhanced flash and turbo-flash with conventional spin-echo sequences as a basis for morphologocal MR imaging for planning high-precision radiotherapy of intracranial brain tumors. Comparison of FLASH-, turbo-FLASH and SE-sequences; Morphologische MR-Bildgebung mit T1-gewichteten Sequenzen zur radiotherapeutischen Zielvolumendefinition von intrakraniellen Tumoren. Vergleich von FLASH-, Turbo-FLASH- und SE-Sequenzen  

Energy Technology Data Exchange (ETDEWEB)

Introduction: The goal of this study was to compare contrast-enhanced T1-weighted Flash and Turbo-Flash sequences with conventional spin-echo sequences as a basis for planning high-precision radiotherapy. Methods: A total of 25 consecutive patients with different intracranial tumors and a disrupted blood-brain barrier were studied. T1-weighted Flash, Turbo-Flash and conventional spin-echo images were evaluated after controlled 30-s infusion of 0.1 mmol/kg body weight of Gd-DTPA. The evaluation of the three sequences included the measurement of the signal- and contrast-to-noise ratios, the visual inspection of the tumors and artifacts, and the measurement of tumor size. Results: The signal- and contrast-to-noise ratios were significantly (P<0.05-0.01) lower for Flash and Turbo-Flash than for conventional spin-echo sequences. However, visual inspection of the contrast-enhancing tumors revealed in 23 ...

1997-03-01

123

The reaction of hydroxylamine with bacteriorhodopsin studied with mutants that have altered photocycles: Selective reactivity of different photointermediates  

Energy Technology Data Exchange (ETDEWEB)

The reaction of the retinylidene Schiff base in bacteriorhodopsin (bR) to the water-soluble reagent hydroxylamine is enhanced by greater than 2 orders of magnitude under illumination. We have used this reaction as a probe for changes in Schiff base reactivity during the photocycle of wild-type bR and mutants defective in proton transport. We report here that under illumination at pH 6, the D85N mutant has a 20-fold lower rate and the D212N mutant has a greater than 4-fold higher rate for the light-dependent reaction with hydroxylamine compared with wild-type bR. In contrast, the reactivities of wild-type bR and the D96N and T46V mutants are similar. It has been previously shown that the D96N and T46V replacements have no significant effect on the kinetics of M formation but have dramatic effects on rate of the decay of M. We therefore conclude that the hydroxylamine reaction occurs before formation of the M intermediate. Most likely it occurs ...

1991-03-15

124

Strain dependence of Si-Ge interdiffusion in epitaxial Si/Si{sub 1-y}Ge{sub y}/Si heterostructures on relaxed Si{sub 1-x}Ge{sub x} substrates  

Science.gov (United States)

The strain dependence of Si-Ge interdiffusion in epitaxial Si/Si{sub 1-y}Ge{sub y}/Si heterostructures on relaxed Si{sub 1-x}Ge{sub x} substrates has been studied using secondary ion mass spectrometry, Raman spectroscopy, and simulations. At 800 and 880 deg. C, significantly enhanced Si-Ge interdiffusion is observed in Si/Si{sub 1-y}Ge{sub y}/Si heterostructures (y=0.56, 0.45, and 0.3) with Si{sub 1-y}Ge{sub y} layers under compressive strain of -1%, compared to those under no strain. In contrast, tensile strain of 1% in Si{sub 0.70}Ge{sub 0.30} layer has no observable effect on interdiffusion in Si/Si{sub 0.70}Ge{sub 0.30}/Si heterostructures. These results are relevant to the device and process design of high mobility dual channel and heterostructure-on-insulator metal oxide semiconductor field effect transistors.

2006-01-02

125

Production of bone cement composites: effect of fillers, co-monomer and particles properties  

International Nuclear Information System (INIS)

Artificial bone cements (BCs) based on poly(methyl methacrylate) (PMMA) powders and methyl methacrylate (MMA) liquid monomer also present in their formulation small amounts of other substances, including a chemical initiator compound and radiopaque agents. Because inadequate mixing of the recipe components during the manufacture of the bone cement may compromise the mechanical properties of the final pieces, new techniques to incorporate the fillers into the BC and their effect upon the mechanical properties of BC pieces were investigated in the present study. PMMA powder composites were produced in situ in the reaction vessel by addition of X-ray contrasts to the reacting MMA mixture. It is shown that this can lead to much better mechanical properties of test pieces, when compared to standard bone cement formulations, because enhanced dispersion of the radiopaque agents can be achieved. Moreover, it is shown that the addition of hydroxyapatite ...

126

MRT in differentiation between tumour and implant material in the postoperative sella. Differenzierung zwischen Tumor und Implantatmaterial in der postoperativen Sella mit der MRT  

Energy Technology Data Exchange (ETDEWEB)

MRT criteria have been developed to distinguish between tumour and implant material following examination of 50 patients who had transsphenoidal hypophysectomies for tumours. Judgements were based on the postoperative hormonal status and the operation notes. Following contrast injection of Gd-DTPA and using T[sub 1] weighted spin-echo sequences, implant material appeared as sandwich-like, linear or circular structures. Residual recurrent tumour produced homogenous or non-homogenous aspects without marginal enhancement in 84% of cases. Postoperative displacement of the infundibulum to the opposite side was observed in 73% of patients with tumour remnants. Sensitivity of MRT was 70%, specificity 95%. There was a positive predictive value of 94% and a negative predictive value of 72% with an accuracy of 81%. This provides assistance in differentiating between tumour remnants and implant material. MRT is recommended as a method of examination for ...

1993-06-01

127

MRT in differentiation between tumour and implant material in the postoperative sella  

International Nuclear Information System (INIS)

MRT criteria have been developed to distinguish between tumour and implant material following examination of 50 patients who had transsphenoidal hypophysectomies for tumours. Judgements were based on the postoperative hormonal status and the operation notes. Following contrast injection of Gd-DTPA and using T_1 weighted spin-echo sequences, implant material appeared as sandwich-like, linear or circular structures. Residual recurrent tumour produced homogenous or non-homogenous aspects without marginal enhancement in 84% of cases. Postoperative displacement of the infundibulum to the opposite side was observed in 73% of patients with tumour remnants. Sensitivity of MRT was 70%, specificity 95%. There was a positive predictive value of 94% and a negative predictive value of 72% with an accuracy of 81%. This provides assistance in differentiating between tumour remnants and implant material. MRT is recommended as a method of examination for ...

128

MRI in combined subacute degeneration of the spinal cord; MRT bei funikulaerer Myelose  

Energy Technology Data Exchange (ETDEWEB)

The MRI morphology in combined subacute degeneration has only rarely been reported. We describe two patients suffering from subacute combined degeneration of the spinal cord on the basis of a deficiency of vitamin B{sub 12}. In both patients characteristic hyperintense areas on T{sub 2}-weighted images in the posterior columns of the cervical and thoracic cord without contrast enhancement were demonstrated by MRI. (orig.) [Deutsch] Bisher liegen zur wenige Beschreibungen der MR-Morphologie bei funikulaerer Myelose vor. Wir beschreiben zwei Patienten mit den klinischen Zeichen einer funikulaeren Myelose auf der Basis eines Vitamin B{sub 12}-Mangels. Bei beiden konnten mit der MRT charakteristische Signalanhebungen im T{sub 2}-gewichteten Bild in den Hinterstraengen des zervikalen und thorakalen Rueckenmarks gezeigt werden. Eine Kontrastmittelaufnahme war nicht nachweisbar. (orig.)

1999-06-01

129

Intracranial tuberculoma: MR imaging  

International Nuclear Information System (INIS)

MR studies of 6 patients with intracranial tuberculoma are reviewed. All patients also underwent CT scans which showed hypo- or isodense lesions with abnormal enhancement following contrast administration. MR showed lesions with prolongation of the T1 relaxation time in every case. On the T2-weighted sequences, the signal properties of the tuberculoma varied according to the stage of evolution of the lesion. Incipient tuberculomas appeared as scattered areas of hypointensity surrounded by edema. Mature tuberculomas were composed of a dark necrotic center surrounded by an isointense capsule which was, in turn, surrounded by edema. In one patient, the center of the lesion was hyperintense probably because of liquefaction and pus formation (tuberculous abscess). While both, CT and MR, were equally sensitive in visualizing the intracranial tuberculoma in every patient, MR was slightly superior in demonstrating the extent of the lesion, especially ...

1988-11-01

130

Intestinal accumulation of lead salts and milk lead by suckling rats  

International Nuclear Information System (INIS)

Absorption of lead is known to be enhanced during infancy. In this study, the sites of intestinal accumulation of Pb by suckling rats have been determined under various conditions using "2"0"3Pb as a tracer. When "2"0"3Pb was administered intragastrically (IG) as a soluble salt, accumulation occurred primarily in the duodenum, regardless of dose and vehicle. In contrast, when rat pups suckled from a dam which had received "2"0"3Pb, the only region of the small intestine showing accumulation of radioactivity was the ileum. To confirm that these differences were not related to the route of administration, rat milk was labeled with "2"0"3Pb and was then used for IG administration. Once again, accumulation (4 hr post-administration) was confined to the ileum. When the dose was increased 10-fold, milk Pb displayed some accumulation in duodenal tissue, but very much less than that of soluble Pb at the same time and dosage. At 20 hr ...

131

Comparison of plasma chemistries for inductively coupled plasma etching of InGaAlP alloys  

International Nuclear Information System (INIS)

Two plasma chemistries, i.e., CH_4/H_2/Ar and Cl_2/Ar, were compared for the etching of InGaP, AlInP, and AlGaP under inductively coupled plasma (ICP) conditions. While the etching with CH_4/H_2/Ar discharges appears to be ion driven, Cl_2/Ar discharges showed an additional strong chemical enhancement. The highest etch rate (#approx#1 #mu#m/min) for InGaP was achieved at high ICP source power (#>=#750 W) with the Cl_2/Ar chemistry. Cl_2/Ar discharges provided very smooth surfaces in all three materials with root-mean-square roughness measured by atomic force microscopy around 2 nm. This result may be due to the efficient ion-assisted product desorption in this chemistry. The etched near-surface region of InGaP (#approx#100 Angstrom) with Cl_2/Ar maintained almost the same stoichiometry as that of the unetched control. By contrast, the CH_4/H_2/Ar plasma chemistry produced somewhat rougher surfaces and depletion of phosphorous (P) from the ...

1998-05-01

132

CR portal imaging; A linac graphy using storage phosphor imaging systems  

Energy Technology Data Exchange (ETDEWEB)

In portal images with high energy X-ray (10 MV), it is sometimes difficult to verify the irradiation field because of the low contrast. Especially, in the abdominal and pelvic region, the deterioration of portal image quality is remarkable. To solve this problem, we took portal images using computed radiography (FCR). Also, we develop a technique in which a copper plate (3 mm) and lead foil (0.3 mm) are closely set in the front and rear of the photostimulable phosphor plate (imaging plate), for increased energy absorption. As a result, image quality was very high and we confirmed image improvement using observer performance experiments. We made a special cassette which can closely set metallic plates to imaging plate and load FCR-7000 directly. Therefore, image process becomes simple, and suitable for routine work. In computed radiography, image processing (tone scale modification and edge enhancement) is possible, and is advantageous portal ...

1992-07-01

133

CR portal imaging  

International Nuclear Information System (INIS)

In portal images with high energy X-ray (10 MV), it is sometimes difficult to verify the irradiation field because of the low contrast. Especially, in the abdominal and pelvic region, the deterioration of portal image quality is remarkable. To solve this problem, we took portal images using computed radiography (FCR). Also, we develop a technique in which a copper plate (3 mm) and lead foil (0.3 mm) are closely set in the front and rear of the photostimulable phosphor plate (imaging plate), for increased energy absorption. As a result, image quality was very high and we confirmed image improvement using observer performance experiments. We made a special cassette which can closely set metallic plates to imaging plate and load FCR-7000 directly. Therefore, image process becomes simple, and suitable for routine work. In computed radiography, image processing (tone scale modification and edge enhancement) is possible, and is advantageous portal ...

1992-01-01

134

Anomalous phosphorus diffusion in Si during postimplantation annealing  

Energy Technology Data Exchange (ETDEWEB)

The transient behavior of P diffusion in Si implanted with As or Ge above the amorphizing threshold has been investigated. Annealing at 720{degree}C after Ge implantation induces extensive P segregation into the extended defect layer formed by implantation damage. This segregation is attributed to P trapping to end-of-range {l_brace}311{r_brace} defects and dislocation loops. For As implantation, P segregation was also observed only after 1 min annealing. However, in contrast to the Ge implantation, in the As-implanted samples, significant P depletion occurs in the As-tail region after further annealing. Nonequilibrium simulation that takes into account both Fermi-level and electric field effects shows the P depletion during transient enhanced diffusion. Furthermore, simulation results based on the coexistence of neutral and positively charged phosphorus-interstitial pairs agree well with the obtained experimental results. {copyright} 2001 ...

2001-06-11

135

A kinetic Monte Carlo annealing assessment of the dominant features from ion implant simulations  

International Nuclear Information System (INIS)

Ion implantation and subsequent annealing are essential stages in today's advanced CMOS processing. Although the dopant implanted profile can be accurately predicted by analytical fits calibrated with SIMS profiles, the damage has to be estimated with a binary collision approximation implant simulator. Some models have been proposed, like the '+n', in an attempt to simplify the anneal simulation. We have used the atomistic kinetic Monte Carlo dados to elucidate which are the implant modeling features most relevant in the simulation of transient enhanced diffusion (TED). For the experimental conditions studied we find that the spatial correlation of the I, V Frenkel pairs is not critical in order to yield the correct I supersaturation, that can be simulated just taking into account the net I-V excess distribution. In contrast to, simulate impurity clustering/deactivation when there is an impurity concentration comparable to the net I-V excess, ...

2004-12-15

136

Transarterial Chemoembolization (TACE) for Inoperable Intrahepatic Cholangiocarcinoma  

International Nuclear Information System (INIS)

The aim of this retrospective study was to determine the safety and efficacy of chemoembolization (TACE) as palliative treatment for patients with unresectable intrahepatic cholangiocarcinoma (CCA) and to compare the results with those in the literature. Fifteen patients with histology-proven CCA (5 men, 10 women) had received palliative treatment with TACE over a 6-year period. The treatment protocol comprised repeated TACE at a minimum of 8-week intervals. TACE was performed with a mixture of 10 ml Lipiodol and 10 mg mitomycin C injected into the tumor-supplying vessels. Follow-up investigations after 8-10 weeks comprised contrast-enhanced multislice spiral CT and laboratory control. Statistical evaluation included survival analysis using the Kaplan-Meier method. During the investigation period 58 TACEs (3.9 #+-# 3.8; 1-15) were performed in 15 patients. Mean tumor size was 10.8 #+-# 4.6 cm (range, 2.0-18.0 cm). Unifocal tumor disease was diagnosed in eight ...

2007-11-01

137

Presentation of Type B Peptide-MHC Complexes from Hen Egg White Lysozyme by TLR Ligands and Type I IFNs Independent of H2-DM Regulation.  

Science.gov (United States)

In APCs, presentation by MHC II molecules of the chemically dominant peptide from the protein hen egg white lysozyme (HEL) generates different conformational isomers of the peptide-MHC II complexes (pMHC). Type B pMHCs are formed in early endosomes from exogenous peptides in the absence of H2-DM, whereas in contrast, type A pMHC complexes are formed from HEL protein in late vesicles after editing by H2-DM. Thus, H2-DM edits off the more unstable pMHC complexes, which are not presented from HEL. In this study, we show that type B pMHC complexes were presented from HEL protein only after stimulation of dendritic cells (DC) with TLR ligands or type I IFN. Type I IFN contributed to most TLR ligand-induced type B pMHC generation, as presentation decreased in DC lacking the receptor for type I IFNs (IFNAR1(-/-)). In contrast, presentation of type A pMHC from HEL and from peptide was minimally affected by TLR ligands. The relative effectiveness of ...

2011-07-25

138

Diagnosis of plasmocytomas using magnetic resonance imaging  

International Nuclear Information System (INIS)

Background. In multiple myeloma 5 different infiltration patterns can be differentiated: 1. Normal appearance of bone marrow, 2. focal involvement, 3. homogeneous diffuse infiltration, 4. combined diffuse and focal infiltration, 5. 'salt-and pepper' pattern with inhomogeneous bone marrow with interposition of fat islands. Methods. For the fast and total acquisition of all patterns a combination of a T1-weighted spin echo sequence and a fat suppression technique is superior. The focal involvement is clearly demonstrated as areas of high signal intensity on e.g. STIR images. Diffuse involvement can be quantified objectively by calculation of the percentage of signal intensity increase after contrast material injection. MRI is superior to X-ray in focal and diffuse involvement. With ultrafast sequences a 'screening' of the whole red bone marrow as for myeloma infiltration is possible. Prognosis. In prognosis studies diffuse infiltration is inferior to focal ...

2000-08-01

139

Anatomical changes after radical surgery and reconstruction with pedunculated or revascularized flaps in advanced head and neck cancer: CT and MR features; Modificazioni anatomiche dopo chirurgia radicale e ricostruzione con lembi peduncolati o rivascolarizzati nei tumori cervico-facciali negli stadi avanzati: Aspetti con Tomografia Computerizzata e Risonanza Magnetica  

Energy Technology Data Exchange (ETDEWEB)

January, 1992, to October, 1995, sixty-four patients with advanced head and neck cancer underwent head and neck reconstructive surgery using myocutaneous or revascularized flaps; in the same period, all patients were consecutively examined with CT and MRI. Myocutaneous flaps were used in 26 patients: 12 flaps were tubular and 14 linear. Revascularized flaps were used in 38 patients: to repair a large defect in 26 patients (14 latissimus dorsi flaps and 12 temporal muscle flaps) and to repair an oral damage in 12 patients (5 revascularized radial and 7 jejunal flaps). CT and MR images of myocutaneous flaps showed the flaps as fatty areas, repairing large surgical defects, hypodense at CT and hyperintense at MRI, with no post-contrast enhancement. The appearance of revascularized flaps at CT and MRI depends on the characteristics of the structure used to repair the surgical defect: jejunal and radial flaps appeared as mostly fatty thickened ...

1997-04-01

140

Anatomical changes after radical surgery and reconstruction with pedunculated or revascularized flaps in advanced head and neck cancer: CT and MR features  

International Nuclear Information System (INIS)

January, 1992, to October, 1995, sixty-four patients with advanced head and neck cancer underwent head and neck reconstructive surgery using myocutaneous or revascularized flaps; in the same period, all patients were consecutively examined with CT and MRI. Myocutaneous flaps were used in 26 patients: 12 flaps were tubular and 14 linear. Revascularized flaps were used in 38 patients: to repair a large defect in 26 patients (14 latissimus dorsi flaps and 12 temporal muscle flaps) and to repair an oral damage in 12 patients (5 revascularized radial and 7 jejunal flaps). CT and MR images of myocutaneous flaps showed the flaps as fatty areas, repairing large surgical defects, hypodense at CT and hyperintense at MRI, with no post-contrast enhancement. The appearance of revascularized flaps at CT and MRI depends on the characteristics of the structure used to repair the surgical defect: jejunal and radial flaps appeared as mostly fatty thickened ...

1997-01-01

141

Vessel wall MRI of the thoracic aorta: correlation to histology and transesophageal ultrasound. Preliminary results  

Energy Technology Data Exchange (ETDEWEB)

Purpose: To visualise the vessel wall of the descending thoracic aorta using magnetic resonance imaging. To evaluate the diagnostic potential of tailored T{sub 1}-weighted sequences with contrast enhancement to assess systemic atherosclerotic disease. Methods: This study was performed on a clinical 1.5 Tesla scanner using a gradient strength of 30 mT/m and the phased array spine coil. A cadaver was examined to optimise a magnetic resonance imaging (MRI) protocol to evaluate atherosclerotic aortic wall disease. The acquired MR images were compared to gross specimens and histology. Subsequently seven patients who had undergone transesophageal ultrasound (TEU) with detailed assessment of the descending thoracic aorta were examined with MRI. The optimised protocol included untriggered and fat suppressed T{sub 2}-weighted turbo spin echo sequences and ECG-triggered and fat suppressed T{sub 1}-weighted spin echo sequences before and after iv ...

2002-05-01

144

Trace metal characterization of the U-Al matrix by atomic spectroscopy  

International Nuclear Information System (INIS)

Uranium-aluminum alloys with a significant enrichment of uranium with "2"3"3U or "2"3"5U serve as nuclear fuels in research reactors. The quality assurance of this fuel requires, among other things, precise knowledge that all trace metal constituents that affect neutron economy, fuel integrity, and fuel fabrication process parameters are well within the specification limits. Trace metal characterization of "2"3"5U-Al alloy has been carried out by atomic spectrometry. The trace metal constituents of interest are grouped into common metals (silver, boron, calcium, cadmium, cobalt, chromium, copper, iron, magnesium, manganese, molybdenum, sodium, nickel, lead, silicon, tin, titanium, vanadium, tungsten, and zinc) and lanthanides (cerium, dysprosium, europium, gadolinium, holminium, lutetium, samarium, and terbium). The elements yttrium and zirconium are grouped with the latter in view of the chemical separation procedure used. The alloy samples are dissolved in 6 M ...

145

Theoretical simulation of SDS - 2 actuation in 540 MWe PHWR  

International Nuclear Information System (INIS)

The 540 MWe PHWR has two fully independent shutdown systems. The first shutdown system (SDS-1) comprises of 28 spring assisted, vertical gravity drop shut-off rods, each consisting of a cadmium absorber sandwiched between stainless steel tubes. The second shutdown system (SDS-2) constitutes six poison tanks connected to respective zircaloy injection tubes. This system is capable of high speed injection of gadolinium nitrate solution (in D2O) into the moderator through these tubes. Theoretical estimation was carried out at different injection pressures and different concentration of gadolinium nitrate solution to arrive at the limiting value of these parameters from reactivity consideration point of view. The plant measurements of SDS-2 actuations at 60 and 80 Kg/cm2 pressure of helium was used to validate and upgrade the estimation model. The paper gives the details of the validation details of SDS-2 actuation. (author)

2006-11-13

146

Uranium isotopic assay instrument  

International Nuclear Information System (INIS)

Full text: The isotopic assay instrument under development at Pacific Northwest National Laboratory (PNNL) is capable of rapid prescreening to detect small and rare particles containing high concentrations of uranium in a heterogeneous sample. The isotopic measurement concept is based on laser vaporization of solid samples followed by sensitive isotope-specific detection using either uranium atomic fluorescence emission or uranium atomic absorbance. Both isotopes are measured concurrently, following a single ablation laser pulse using two external-cavity violet diode lasers. The simultaneous measurement of both isotopes enables the correlation of the fluorescence and absorbance signals on a shot-to-shot basis. This measurement approach demonstrated negligible channel crosstalk between isotopes. Scanning the heterogeneous samples provides high-resolution imagery of sample isotopic fluorescence and absorbance. Isotopically selective excitation of uranium vapor also was the basis of the ...

2006-10-16

147

Phase diagrams  

International Nuclear Information System (INIS)

The description is presented of binary phase diagrams of titanium alloyed with the following elements: silver, aluminium, arsenic, gold, boron, barium, beryllium, bismuth, carbon, calcium, cadmium, cobalt, chromium, copper, iron, gallium, germanium, hydrogen, hafnium, indium, iridium, potassium, lithium, magnesium, manganese, molybdenum, nitrogen, sodium, niobium, nickel, oxygen, osmium, phosphorus, lead, palladium, platinum, plutonium, rhenium, lanthanium, cerium, preseodymium, neodymium, gadolinium, erbium, terbium, thulium, lutetium, rhodium, ruthenium, scandium, silicon, tin, strontium, tantalum, technetium, thorium, uranium, vanadium, tungsten, yttrium, ytterbium, zinc and zirconium.

148

Effect of vitamin D on the intestinal absorption of 203Pb and 47Ca in chicks  

Energy Technology Data Exchange (ETDEWEB)

The transfer of 203Pb and/or 47Ca across the intestinal epithelium of the chick was investigated, with emphasis given to the functional role of cholecalciferol (vitamin D-3). 203Pb, after introduction in the intestinal lumen, is rapidly accumulated by the intestinal tissue, and only a fraction of 203Pb is translocated parenterally (absorbed). Cholecalciferol did not significantly affect the accumulation of 203Pb by intestinal tissue but did accelerate 203Pb movement across the basal-lateral membrane. In contrast, cholecalciferol both decreased 47Ca tissue levels and increased 47Ca absorption. In rachitic chicks, the rate of absorption of 203Pb was greater in the distal than in the proximal segments of the intestine; after cholecalciferol repletion, the degree of absorption in al segments was similar, indicting the order of cholecalciferol effectiveness as duodenum greater than or equal to jejunum greater than ileum. An acute dose of 1,25(OH)2D3 to rachitic chicks ...

1982-03-01

149

Effect of vitamin D on the intestinal absorption of /sup 203/Pb and /sup 47/Ca in chicks  

Energy Technology Data Exchange (ETDEWEB)

The transfer of /sup 203/Pb and/or /sup 47/Ca across the intestinal epithelium of the chick was investigated, with emphasis given to the functional role of cholecalciferol (vitamin D-3). /sup 203/Pb, after introduction in the intestinal lumen, is rapidly accumulated by the intestinal tissue, and only a fraction of /sup 203/ Pb is translocated parenterally (absorbed). Cholecalciferol did not significantly affect the accumulation of /sup 203/Pb by intestinal tissue but did accelerate /sup 203/Pb movement across the basal-lateral membrane. In contrast, cholecalciferol both decreased /sup 47/Ca tissue levels and increased /sup 47/Ca absorption. In rachitic chicks, the rate of absorption of /sup 203/Pb was greater in the distal than in the proximal segments of the intestine; after cholecalciferol repletion, the degree of absorption in all segments was similar, indicating the order of cholecalciferol effectiveness as duodenum greater than or equal to jejunum > ileum. ...

1982-03-01

150

Influence of contrast-enhanced CT and MRI with or without SPIO particles on therapy and therapy costs for patients with focal liver disease; Einfluss von biphasischer Spiral-CT, nativer und eisenoxidverstaerkter MRT auf Therapie und Therapiekosten bei Patienten mit fokalen Leberlaesionen  

Energy Technology Data Exchange (ETDEWEB)

Purpose: Evaluation of the diagnostic efficacy and cost-benefit of contrast enhanced CT (CT) and MRI pre- and post-SPIO-particles in focal hepatic disease with consideration of therapeutic outcome. Results: In 34/52 (65.4%) of the cases the correct diagnosis was primarily stated by CT (sensitivity [se.] 85.2%, specificity [sp.] 44.0%). In additional 10/52 of the cases unenhanced MRI (se. 91.4%, sp. 75.0%) enabled correct diagnoses, and in another 6 cases the diagnosis was established only by SPIO-MRI (se. 100%, sp. 86.7%). Considering the possible therapeutic recommendation arising from each modality, CT would have induced needless therapy costs of 191,042 DM, unenhanced MRI of 171,035 DM, and SPIO-MRI of 7,311 DM. In comparison to the real therapy costs of 221,873 DM, this would have corresponded to an unnecessary increase of therapy costs of 86.1%, 77.1%, and 3.3%, respectively. In two cases (91 hemangioma, 1 regenerative nodule) all ...

2000-03-01

151

Control of Phosphorus Transient Enhanced Diffusion using Co-implantation  

CERN Document Server

Control of Phosphorus Transient Enhanced Diffusion using Co-implantation

2006-01-01

152

Computed tomography whole body imaging in multi-trauma: 7 years experience  

International Nuclear Information System (INIS)

AIM: To assess the impact of the introduction of a computed tomography (CT) imaging protocol for multi-trauma patients on the workload, overall diagnostic yield, and effect on detection of cervical spine injury and pneumothorax. METHOD: Between February 1997 and April 2004, all patients presenting acutely to the Emergency Department (ED) with haemodynamically stable trauma (Abbreviated Injury Scale 3 or more) involving more than two body systems were imaged with a comprehensive pre-set helical CT protocol (including non-contrast head, cervical spine: cranio-cervical and cervico-thoracic junctions; and oral and intravenous contrast-enhanced thoracic, abdomen and pelvis) after initial triage and a standard trauma series of radiographs (chest, lateral C-spine and pelvis). Diagnosis of cervical spine fracture and pneumothorax was noted before and after the CT protocol was carried out and findings from all studies were recorded prospectively. ...

2006-04-01

153

Computed tomography and magnetic resonance imaging of acquired abnormalities of the inner ear and cerebello-pontine angle; CT und MRT erworbener Veraenderungen des Innenohrs und Kleinhirnbrueckenwinkels  

Energy Technology Data Exchange (ETDEWEB)

CT and MRI of acquired abnormalities of the inner ear and cerebello-pontine angle present themselves with very typical findings. The imaging should be adapted to the pathology looked for and either CT or MRI should be used alone or in combination.CT, especially high resolution CT (HRCT), provides an excellent bone contrast, while MRI has a much superior soft tissue contrast. Acute inflammatory changes of the inner ear are solely depicted by contrast-enhanced MRI. HRCT excellently depicts osseous changes of the inner ear and cerebellopontine angle such as chronic ossifying labyrinthitis occurring after acute labyrinthitis, otosclerotic or traumatic changes. Tumorous changes not yielding to bony changes are best delineated by MRI. Posttraumatic hemorrhage and chronic fibrotic changes within the labyrinth are depicted by MRI, only. In conclusion HRCT and MRI are excellent methods to delineate acquired abnormalities of the ...

2003-03-01

154

Selective imaging of adherent targeted ultrasound contrast agents  

UK PubMed Central (United Kingdom)

The goal of ultrasonic molecular imaging is the detection of targeted contrast agents bound to receptors on endothelial cells. We propose imaging methods that can distinguish adherent microbubbles...Full Text Available

2007-04-21

155

On the internal perceptual structure of distinctive features: The [voice] contrast  

UK PubMed Central (United Kingdom)

Several fixed classification experiments test the hypothesis that F1, f0, and closure voicing covary between intervocalic stops contrasting...Full Text Available

2008-01-01

156

High Contrast Near-infrared Polarized Reflectance Images of Demineralization on Tooth Buccal and Occlusal Surfaces at ?=1310-nm  

UK PubMed Central (United Kingdom)

Background and Objectives:Sound enamel manifests peak transparency in the near-IR (NIR) at 1310-nm, therefore the near-IR is ideally suited for high contrast imaging...Full Text Available

2009-03-01

157

Analysis of the Sulfate-Reducing Bacterial and Methanogenic Archaeal Populations in Contrasting Antarctic Sediments  

UK PubMed Central (United Kingdom)

The distribution and activity of communities of sulfate-reducing bacteria (SRB) and methanogenic archaea in two contrasting Antarctic sediments were investigated. Methanogenesis dominated in freshwater...Full Text Available

2003-06-01

158

Genetic Applications in Avian Conservation  

Science.gov (United States)

... structure along an elevational gradient in Hawaiian honeycreepers reveals contrasting evolutionary responses to avian malaria. BMC Evolutionary Biology 8: ... ...

160

Addition of methyl cellulose enema to double-contrast barium imaging of sigmoid diverticulosis  

Energy Technology Data Exchange (ETDEWEB)

Double-contrast barium enema has a reduced sensitivity in patients with severe sigmoid diverticulosis. Therefore a carboxy methyl cellulose enema was employed after the conventional double-contrast examination in 15 patients with sigmoid diverticulosis. A significant increase in lumen diameter and a superior removal of barium residue from the diverticulas facilitated the interpretation of the sigmoid loops. Conclusion: The addition of methyl cellulose enema to double-contrast barium imaging improves diagnostic imaging in diverticulosis by expanding the lumen and emptying the diverticulas. (orig.).

1997-01-01

161

AM: An Artificial Intelligence Approach to Discovery in ...  

Science.gov (United States)

... For example, contrast solving the Missionaries and Cannibals problem with the more ill-defined reasoning which led to inventing it. ...

1976-07-01

162

A bright field scanning transmission electron microscope (STEM ...  

Science.gov (United States)

A bright field scanning transmission electron microscope (STEM) micrograph showing a Wassonite grain in dark contrast. ...

163

Advantages of magnification in digital phase-contrast mammography using a practical X-ray tube  

Energy Technology Data Exchange (ETDEWEB)

Phase-contrast imaging with a practical cone-beam X-ray tube has been realized for clinical use in digital mammography using computed radiography (CR). To perform phase-contrast imaging, the X-ray detector must be distanced from an object so that the phase-contrast image achieves magnification; in a mammography unit dedicated to phase-contrast imaging, the magnification ratio is 1.75. When using an X-ray tube with a 0.1-mm focal spot, it appears that the penumbra in magnification blurs both projected images and the phase contrast, which generates an edge effect. However, where the sampling pitch of the CR plate is 43.75 {mu}m, the blur stretches the width of the phase contrast so that unit pixels in the detector can capture it. Note that the width of an ideal phase contrast using an X-ray point source results in a phase ...

2008-12-15

164

Clinically silent heterotaxy with polysplenia syndrome and IVC azygous continuation draining to SVC: CT findings. Case report  

International Nuclear Information System (INIS)

Patients with heterotaxy syndrome often have complex cardiac and extracardiac anomalies requiring further detailed diagnostic evaluation. They often present severe cardiac failure early in life. Newer radiological modalities in the form of spiral computed tomography (CT) and three-dimensional reconstruction of spiral CT allow clear definition of the anatomy of these anomalies. A 59-year-old woman was diagnosed with polysplenia and multiple anomalies in an abdominal ultrasonography (US) during a control medical examination due to a trivial dietary mistake. She was then referred to our institution for further examination of these anomalies and an additional thoraco-abdominal computed tomography (CT) examination. The patient was totally asymptomatic at the time of admission. There was no significant past history and no abnormal laboratory data. We performed abdominal, pelvic and thoracic CT examinations using Somatom Siemens Emotion scanner. Non-enhanced sections were ...

2007-01-01

165

Theoretical considerations for X-ray phase contrast mammography by Thomson source  

Energy Technology Data Exchange (ETDEWEB)

The advent, in the near future, of compact X-ray sources like Thomson Back-Scattering (TBS) will allow the clinical application of advanced X-ray imaging techniques, such as phase contrast, with higher sensitivity and lower impact in terms of dose delivery. In this work, we theoretically investigated the possibility of using such sources for phase contrast imaging of micro-calcifications included in a breast tissue. In our study we analyzed the phase and amplitude distribution of the TBS source and we showed that this source can be used for phase contrast imaging since the source coherence at the sample position is sufficiently high for achieving good contrast and micrometer spatial resolution. Indeed the spatial coherence of a TBS source is closer to that of a synchrotron radiation source, and much better than that of a laboratory source. Moreover, we showed the advantages of phase imaging with respect ...

2009-09-01

166

Relativistic distorted-wave results for nickel-like gadolinium  

Science.gov (United States)

Electron collisional data are required for population kinetics modeling and spectral predictions of highly ionized ions in high-temperature plasmas. Nickel-like ions are especially interesting for their potential use in soft X-ray laser schemes pumped by electron collisional excitation and recombination. For highly stripped ions of moderate to high Z, relativistic effects begin to play a role in the atomic-physics calculations. A relativistic multiconfigurational distored-wave model has been used for the calculation of electron excitation cross sections and rate coefficients between the 3s2 3p6 3d10 Ni-like Gd ground state and the singly excited states with an N-shell electron.

1986-08-01

167

Real time neutron radioscopy - trends and applications  

International Nuclear Information System (INIS)

Real Time Radiography (RTR) finds extensive applications for inspection of objects on assembly lines for rapid inspection. A typical RTR widely used includes a image intensifier, CCD camera, image processor and high resolution TV monitor in addition to radiographic source. Image intensifiers used in X-radiography employ CsI as the input detector. With the increased use of neutrons as radiation source, real time neutron radiography is also being practised widely. Image intensifiers used in neutron radiography employ gadolinium as the input screen. The neutron image intensifier system at the authors laboratory essentially consists of a 9 inch Trifield image intensifier tube, motorised zoom lens, CCD camera and a high resolution TV monitor

2003-11-12

168

Powder characteristics and microstructure of uranium dioxide and uranium dioxide-gadolinium oxide fuel  

Energy Technology Data Exchange (ETDEWEB)

Three different fuels UO{sub 2}-only, UO{sub 2}-Gd{sub 2}O{sub 3}(5%), and UO{sub 2}-Gd{sub 2}O{sub 3}(10%) were produced by sol-gel technique. Their powder characteristics such as flowability, BET surface area, average pore diameter, and cumulative pore volume were determined. The pore size distributions of powders, green pellets, and sintered fuels were determined by using a mercury porosimeter. The theoretical densities of sintered fuels were found to be 98.01, 95.3, and 95.9 %, respectively. Their ruggedness fractal dimensions were 1.111, 1.044, and 1.042, while the fractal dimensions associated with the size distribution of grains were 1.44, 1.58, and 1.60, respectively. (orig.).

1996-07-01

169

Electrochemical and gas phase parameters of cathodes for intermediate temperature solid oxide fuel cells  

International Nuclear Information System (INIS)

A series of cyclic voltammetry, chronoamperometry and electrochemical impedance experiments have been carried out in order to investigate the effect of cathode composition and porosity on the electrochemical characteristics of strontium-doped lanthanum, praseodymium and gadolinium cobaltite cathodes. The impedance responses at different electrode potentials of the half cell and symmetric single cell setups are compared and analyzed by the equivalent circuit modeling method. The deconvolution of impedance spectra for single cell cathode and anode reactions contributions based on the results of simultaneous analysis of half cells and symmetric single cells has been made by differential impedance real part vs. ac frequency plot analysis method. Noticeable influence of cathode chemical composition, meso-porosity and macro-porosity on the electrochemical activity of the oxygen electroreduction has been demonstrated. Seeming activation energy values have been calculated ...

2010-11-01

170

Design on SDS2 on-line poison concentration monitoring in CANDU  

Energy Technology Data Exchange (ETDEWEB)

At the reference plant (Wolsung unit No. 1) a manual poison sampling system is provided to periodically sample gadolinium from each tank and analyze it in the laboratory to provide assurance that adequate poison concentration in each tank is maintained. The AECB required a continuous, on-line monitoring system. On Wolsung unit No. 2, process piping adapter and new instrument loops added to the Liquid Injection Shutdown System(LISS) which is part of SDS2. The new instrument loops continuously monitor SDS2 poison conductivity and initiate an alarm when the poison concentration is too low. 8 refs., 1 fig. (author).

1996-10-01

174

Washboard modes as ELM-related events in JET  

Energy Technology Data Exchange (ETDEWEB)

Washboard (WB) modes (Smeulders P et al 1999 Plasma Phys. Control. Fusion 41 1303) are a very common edge instability regularly observed in the H-mode regime in JET. They are detected as (normally several) bands of continuously fluctuating magnetic activity rotating in the direction of the electron diamagnetic drift with typical frequencies in the range of 10-90 kHz. The time evolution of the WB mode frequency is found to follow qualitatively the evolution of the electron temperature measured near the pedestal top, probably due to the strong diamagnetic drift associated with the large pedestal gradients. Evidence for their involvement in the pedestal and ELM dynamics will be presented. Increasing WB mode amplitude is correlated with an increase in the time between consecutive type-I ELMs. In situations in which a sudden increase (decrease) of WB mode activity is observed, the build-up of the pedestal temperature (and, linked to this, also of the pedestal pressure) of the electrons is ...

2004-01-01

175

Sub-0.1 #mu#m line fabrication by Focused ion beam and columnar structural Se-Ge resist  

International Nuclear Information System (INIS)

As a method to enhance the sensitivity (S) of an inorganic resist for focused-ion-beam (FIB), lithography, sub-0.1 #mu#m patterning properties of a columnar structural #alpha#-Se_7_5Ge_2_5 resist have been investigated using 30 keV low-energy Ga"+-FIB exposure and CF_4 reactive-ion etching (RIE). development. The Se_7_5Ge_2_5 thin films were 60 .deg. and 80 .deg. -obliquely deposited on Si substrate and parts of the films were annealed for several minutes at the glass transition temperature (T_g=#approx#220 .deg. C). Columnar structures with the angles of approximately 40 .deg. and 65 .deg. are observed in 60 .deg. and 80 .deg. -obliquely deposited films, respectively, and they disappear after annealing. Despite the disappearance of the columnar structures, a critical decrease in thickness is not observed. For the FIB exposures with a beam diameter of #approx#0.1#mu#m and around the threshold dose, the negative-type fine patterns with linewidth of about ...

1998-11-01

176

Radiofrequency Ablation of Intrahepatic Cholangiocarcinoma: Preliminary Experience  

International Nuclear Information System (INIS)

The purpose of this study was to evaluate the safety and efficacy of percutaneous ultrasound (US)-guided radiofrequency ablation (RFA) in patients with intrahepatic cholangiocarcinoma (ICCA) in a small, nonrandomized series. From February 2004 to July 2008, six patients (four men and two women; mean age 69.8 years [range 48 to 83]) with ICCA underwent percutaneous US-guided RFA. Preintervetional transarterial embolization was performed in two cases to decrease heat dispersion during RFA in order to increase the area of ablation. The efficacy of RFA was evaluated using contrast-enhanced dynamic computed tomography (CT) 1 month after treatment and then every 3 months thereafter. Nine RFA sessions were performed for six solid hepatic tumors in six patients. The duration of follow-up ranged from 13 to 21 months (mean 17.5). Posttreatment CT showed total necrosis in four of six tumors after one or two RFA sessions. Residual tumor was observed in two patients with larger ...

2010-08-01

177

Prosocial effects of nicotine and ethanol in adolescent rats through partially dissociable neurobehavioral mechanisms  

Science.gov (United States)

The widespread use of tobacco and alcohol among adolescents might be related to the ability of nicotine and ethanol to facilitate social interactions. To investigate the neurobehavioral mechanisms underlying the prosocial effects of nicotine and ethanol, we focused on social play behavior, the most characteristic social activity in adolescent rats. Social play behavior is rewarding, and it is modulated through opioid, cannabinoid and dopaminergic neurotransmission, which are also involved in the reinforcing properties of nicotine and ethanol. We found that nicotine and ethanol increased social play, without affecting locomotion or social exploration. Their effects depended on the level of social activity of the partner, and were comparable in familiar and unfamiliar environments. At doses that increased social play, nicotine and ethanol had no anxiolytic effects in the elevated plus-maze. By contrast, the prototypical anxiolytic drug diazepam reduced social play at ...

2009-08-05

178

Preoperative assessment of hilar cholangiocarcinoma using multidetector-row CT. Correlation with histopathological findings  

International Nuclear Information System (INIS)

Our aim was to investigate the diagnostic reliability of multidetector-row computed tomography (MDCT) for preoperative assessment of local tumoral spread in hilar cholangiocarcinoma. Thirteen of 30 consecutive patients with hilar cholangiocarcinoma who underwent surgery, excluding 17 patients who underwent biliary drainage or preoperative portal embolization, were retrospectively evaluated. Using MDCT systems of 4 detector rows or 16 detector rows, plain and dynamic contrast-enhanced images of three phases were obtained. Extent of tumor spread and lymph node metastasis were assessed with MDCT and compared with histopathological findings. The Bismuth-Corlette classification of hilar cholangiocarcinoma with MDCT were type I, 1 patient; type IIIa, 3 patients; type IIIb, 4 patients; and type IV, 5 patients; those with histopathological findings were type I, 1 patient; type IIIa, 2 patients; type IIIb, 4 patients; and type IV, 6 patients. One patient diagnosed as type ...

2008-08-01

179

Optical image storage in ion implanted PLZT ceramics  

International Nuclear Information System (INIS)

We have demonstrated that optical images can be stored in transparent lead-lanthanum-zirconate-titanate (PLZT) ceramics by exposure to near-UV light with photon energies greater than the band gap energy of approx. equal to 3.35 eV. The image storage process relies on optically induced changes in the switching properties of ferroelectric domains (photoferroelectric effect). Stored images are nonvolatile but can be erased by uniform UV illumination and simultaneous application of an electric field. Although high quality images, with contrast variations of >= 100:1 and spatial resolution of approx. equal to 10 #mu#m, can be stored using the photoferroelectric effect, relatively high exposure energies (approx. equal to 100 mJ/cm"2) are required to store these images. This large exposure energy severely limits the range of possible applications of nonvolatile image storage in PLZT ceramics. We have recently found from studies of H, He and Ar implanted PLZT that the ...

180

Novel bifunctional natriuretic peptides as potential therapeutics.  

Science.gov (United States)

Synthetic atrial natriuretic peptide (carperitide) and B-type natriuretic peptide (BNP; nesiritide) are used to treat congestive heart failure. However, despite beneficial cardiac unloading properties, reductions in renal perfusion pressures limit their clinical effectiveness. Recently, CD-NP, a chimeric peptide composed of C-type natriuretic peptide (CNP) fused to the C-terminal tail of Dendroaspis natriuretic peptide (DNP), was shown to be more glomerular filtration rate-enhancing than BNP in dogs. However, the molecular basis for the increased responsiveness was not determined. Here, we show that the DNP tail has a striking effect on CNP, converting it from a non-agonist to a partial agonist of natriuretic peptide receptor (NPR)-A while maintaining the ability to activate NPR-B. This effect is specific for human receptors because CD-NP was only a slightly better activator of rat NPR-A due to the promiscuous nature of CNP in this species. Interesting, the DNP ...

2008-10-21

181

Multislice spiral CT (MSCT) in pediatric radiology: dose reduction for chest and abdomen examinations  

International Nuclear Information System (INIS)

The advent of multislice spiral CT (MSCT) technique has led to new aspects of dose reduction, especially for the dedicated use of MSCT in children. Optimizing pediatric MSCT protocols according to the clinical problem allows reduction of radiation exposure to a minimum without loss of diagnostic quality. The different parameters that influence the degree of dose reduction, like tube current-time product (mAs), tube voltage (kV), collimation and pitch, are discussed in context with previously published data and our own experience in nearly 200 pediatric CT examinations. In our department, the effective mAs is calculated for a pediatric chest MSCT by multiplication of the body weight in kilogram with a factor of 1 to 1.5 and for a pediatric abdominal MSCT by multiplication with a factor of 2 to 2.5. To calculate the equivalent effective dose for a contrast media-enhanced 80 kV protocol, the effective mAs of the 120 kV protocol can be multiplied ...

2004-07-01

182

Intrahepatic peripheral cholangiocarcinoma; dynamic features of CT scans  

International Nuclear Information System (INIS)

To elucidate the dynamic features of CT scans in peripheral cholangiocarcinoma for the differentiation of this tumor from various primary hepatic neoplasms. Materials were 24 cases of pathologically confirmed peripheral cholangiocarcinoma. Contrast enhancement patterns of central and peripheral portion of the masses were analyzed at three phases including arterial dominant(22), tissue equilibria(24), and postequilibria(9). Other associated CT findings and laboratory data were analyzed. Serum total bilirubin was mostly below 2 mg/dl(22/24), hepatitis B surface antigen was positive in only 9%, serum alphafetoprotein was elevated in 18%, carcinoembryonic antigen in 47%, cancer antigen 19-9 in 60%. In the arterial dominant image(22), 50% of the cases showed peripheral hyperdensity and 50% total hypodensity. In the tissue equilibrial images(24), 63% showed total hypodensity, 25% peripheral hyperdensity, and 13% total isodensity. In the ...

1995-05-01

183

Enhanced activity and interfacial durability study of ultra low Pt based electrocatalysts prepared by ion beam assisted deposition (IBAD) method  

International Nuclear Information System (INIS)

Ultra low loading noble metal (0.04-0.12 mg_P_t/cm"2) based electrodes were obtained by direct metallization of non-catalyzed gas diffusion layers via dual ion beam assisted deposition (IBAD) method. Fuel cell performance results reported earlier indicate significant improvements in terms of mass specific power density of 0.297 g_P_t/kW with 250 A thick IBAD deposit (0.04 mg_P_t/cm"2 for a total MEA loading of 0.08 mg_P_t/cm"2) at 0.65 V in contrast to the state of the art power density of 1.18 g_P_t/kW using 1 mg_P_t_(_M_E_A_)/cm"2 at 0.65 V. In this article we report the peroxide radical initiated attack of the membrane electrode assembly utilizing IBAD electrodes in comparison to commercially available E-TEK (now BASF Fuel Cell GmbH) electrodes and find the pathway of membrane degradation as well. A novel segmented fuel cell is used for this purpose to relate membrane degradation to peroxide generation at the electrode/electrolyte interface by means of ...

2009-11-01

184

Comparison of turbo inversion recovery magnitude (TIRM) with T2-weighted turbo spin-echo and T1-weighted spin-echo MR imaging in the early diagnosis of acute osteomyelitis in children  

Energy Technology Data Exchange (ETDEWEB)

Objective. To compare turbo inversion recovery magnitude (TIRM) with standard T1-weighted (T1-W) and T2-weighted (T2-W) MR sequences in the very early detection of acute osteomyelitis in children. Materials and methods. In 15 children with osteomyelitis, 15 sets of T1-W spin-echo (SE) (TR/TE, 400-640/12-17), T2-W turbo spin-echo (TSE) (TR/TE/ETL, 3290-4465/112-120/11), and TIRM (TR/TE/TI, 4000-6120/60/160) images were acquired with a 1.0-T magnet. Contrast-to-noise (C/N) ratios and percentage of signal between lesion and normal bone marrow were analysed with a computer-assisted image analysing system in a region of interest (ROI). Results. In 13 of 15 patients, the absolute signal enhancement in a ROI on the TIRM images was better than on the T1-W SE and T2-W TSE images and in 14 of 15 cases, C/N ratios were also better on the TIRM images than on the other sequences. In the other cases, the TIRM signal was diagnostically equivalent. On the TIRM ...

1998-11-01

185

Comparison of plasma chemistries for inductively coupled plasma etching of InGaAlP alloys  

Science.gov (United States)

Two plasma chemistries, i.e., CH{sub 4}/H{sub 2}/Ar and Cl{sub 2}/Ar, were compared for the etching of InGaP, AlInP, and AlGaP under inductively coupled plasma (ICP) conditions. While the etching with CH{sub 4}/H{sub 2}/Ar discharges appears to be ion driven, Cl{sub 2}/Ar discharges showed an additional strong chemical enhancement. The highest etch rate ({approximately}1 {mu}m/min) for InGaP was achieved at high ICP source power ({ge}750 W) with the Cl{sub 2}/Ar chemistry. Cl{sub 2}/Ar discharges provided very smooth surfaces in all three materials with root-mean-square roughness measured by atomic force microscopy around 2 nm. This result may be due to the efficient ion-assisted product desorption in this chemistry. The etched near-surface region of InGaP ({approximately}100 {Angstrom}) with Cl{sub 2}/Ar maintained almost the same stoichiometry as that of the unetched control. By contrast, the CH{sub 4}/H{sub 2}/Ar plasma chemistry produced ...

1998-05-01

186

Comparison of helmet-mounted display designs in support of infantry wayfinding  

Science.gov (United States)

The Canadian Soldier Information Requirements Technology Demonstration (SIREQ TD) soldier modernization research and development program has conducted experiments to help determine the types and amount of information needed to support wayfinding across a range of terrain environments, the most effective display modality for providing the information (visual, auditory or tactile) that will minimize conflict with other infantry tasks, and to optimize interface design. In this study, seven different visual helmet-mounted display (HMD) designs were developed based on soldier feedback from previous studies. The displays and an in-service compass condition were contrasted to investigate how the visual HMD interfaces influenced navigation performance. Displays varied with respect to their information content, frame of reference, point of view, and display features. Twelve male infantry soldiers used all eight experimental conditions to locate bearings to waypoints. From a ...

2003-09-01

187

Comparison of Stereotactic Radiosurgery and Whole Brain Radiotherapy in Patients with Four or More Brain Metastases  

International Nuclear Information System (INIS)

This study was a retrospective evaluation of the efficacy of stereotactic radiosurgery (SRS) in patients with >4 metastases to the brain. Materials and Methods: Between January 2004 and December 2006, 68 patients with ?4 multiple brain metastases were included and reviewed retrospectively. Twenty-nine patients received SRS and 39 patients received whole brain radiotherapy (WBRT). Patients with small cell lung cancers and melanomas were excluded. The primary lesions were non-small cell lung cancer (69.0%) and breast cancer (13.8%) in the SRS group and non-small cell lung cancer (64.1%), breast cancer (15.4%), colorectal cancer (12.8%), esophageal cancer (5.1%) in the WBRT group. SRS involved gamma-knife radiosurgery and delivered 10?20 Gy (median, 16 Gy) in a single fraction with a 50% marginal dose. WBRT was delivered daily in 3 Gy fractions, for a total of 30 Gy. After completion of treatment, a follow-up brain MRI or a contrast-enhanced brain CT was reviewed. ...

2009-09-01

188

Clinical use of lipiodol in hepatic arteriography  

Energy Technology Data Exchange (ETDEWEB)

Lipiodol, lipid soluble contrast media, was applied to 59 patients, who was clinically suspected to have hepatic tumor, in the Department of Diagnostic Radiology, Seoul National University Hospital. The results of the clinical use of Lipiodol were as follows: 1. The clinical diagnosis was hepatocellular carcinoma (HCC) in 50 cases, cavernous hemangioma in 4 cases, metastasis in one case and others in 4 cases. 2. After hepatic arteriography, Lipiodol only was injected in 28 cases, mixture of Lipiodol and Mitomycin was injected in 22 cases and transcatheter arterial embolization was performed additionally after injection of Lipiodol and Mitomycin in 9 cases. 3. Among the 50 cases of HCC, Lipiodol was accumulated in the lesion in 49 cases. However, similar accumulation of Lipiodol occured in a metastatic cancer and cavernous hemangiomas. 4. Plain radiographic patterns of Lipiodol accumulation could be divided into fine granular type, nodular type and linear or ...

1986-08-15

189

Alcoa titanium alloy Ti-10V-2Fe-3Al forgings -- Data sheets  

International Nuclear Information System (INIS)

Ti-10V-2Fe-3Al is high strength, metastable beta titanium alloy developed by the Timet Division, Titanium Metals Corporation of America for enhanced forgeability and excellent mechanical property combinations, including deep hardening characteristics. Ti-10-2-3 has been the subject of intense thermomechanical processing (TMP) development and reduction to commercial practice for the full range of open die, closed-die and precision forged products utilized in aerospace and other applications. With commercially proven TMP, Ti-10-2-3 forgings provide a range of strength-fracture toughness combinations from 180 Ksi (1,240 MPa) minimum U.T.S. to 140 Ksi (965 MPa) minimum U.T.S with commensurate fracture toughness. With optimal TMP and these strength-toughness combinations, Ti-10-2-3 forgings are found provide superior smooth and notched fatigue properties critical to aerospace applications over incumbent alpha-beta alloys. The alloy retains 80 percent of its room ...

1993-02-21

190

Aerodynamic effects of flexibility in flapping wings.  

Science.gov (United States)

Recent work on the aerodynamics of flapping flight reveals fundamental differences in the mechanisms of aerodynamic force generation between fixed and flapping wings. When fixed wings translate at high angles of attack, they periodically generate and shed leading and trailing edge vortices as reflected in their fluctuating aerodynamic force traces and associated flow visualization. In contrast, wings flapping at high angles of attack generate stable leading edge vorticity, which persists throughout the duration of the stroke and enhances mean aerodynamic forces. Here, we show that aerodynamic forces can be controlled by altering the trailing edge flexibility of a flapping wing. We used a dynamically scaled mechanical model of flapping flight (Re approximately 2000) to measure the aerodynamic forces on flapping wings of variable flexural stiffness (EI). For low to medium angles of attack, as flexibility of the wing increases, its ability to ...

2009-08-19

191

Multiple-Element Eddy Current Probes for Enhanced ...  

Science.gov (United States)

... Accession Number : ADD335251. Title : Multiple-Element Eddy Current Probes for Enhanced Inspection,. Corporate Author : ...

1993-07-01

192

Hydration of swelling clay and bacteria interaction. An experimental in situ reaction study; Hydratation des argiles gonflantes et influence des bacteries. Etude experimentale de reaction in situ  

Energy Technology Data Exchange (ETDEWEB)

This study reports on the physical-chemical behaviour of swelling di-octahedral clays (smectites) and their interaction with aqueous solutions and bacteria (Shewanella putrefaciens). Experimental results are presented for compacted clays, hydrated under confined volume conditions, using a new type of reaction-cell (the 'wet-cell' of Warr and Hoffman, 2004) that was designed for in situ X-ray diffraction (XRD) measurement. For comparison, dispersed clay systems were studied using standard batch solutions subjected to varying degrees of agitation. The combination of time-dependent in situ XRD measurements with gravimetric measurements and calculated diffraction patterns using the CALCMIX software (Plancon and Drits, 1999) allowed to successful quantification of the dynamics of water uptake and storage. This analytical procedure combined with published water vapour adsorption data enabled determination of the abundance of structured water layers, developed in the ...

2008-01-15

193

What is the best contrast injection protocol for 64-row multi-detector cardiac computed tomography?  

International Nuclear Information System (INIS)

Objective: To determine the optimal contrast injection protocol for 64-MDCT coronary angiography. Materials and methods: One hundred and fifty consecutive patients scheduled to undergo retrospectively electrocardiographically gated 64-MDCT. Each 30 patients were assigned to use a different contrast protocol: group 1: uniphasic protocol (contrast injection without saline flush); group 2: biphasic protocol (contrast injection with saline flush); group 3A, 3B and 3C: triphasic protocol (contrast media + different saline diluted contrast media + saline flush). Image quality scores and artifacts were compared and evaluated on both transaxial and three-dimensional coronary artery images among each contrast protocol. Results: Among the triphasic protocol groups, group 3A (30%:70% contrast media-saline mixture was used in second ...

2010-08-01

194

Observation and simulation of the energy levels of the trivalent thulium ion in gadolinium oxychloride  

International Nuclear Information System (INIS)

The optical absorption of the Tm"3"+ ion in the gadolinium oxychloride (GdOCl) matrix in the UV, visible, and NIR range was studied at temperatures between 9 and 300 K. The visible luminescence of GdOCl:Tm"3"+ under Ar"+ ion laser and mercury lamp excitation was recorded at 9, 77, and 300 K, too. The crystal field (CF) splitting of the "3H_4_-_6, "3F_2_-_4, "1G_4, "1D_2, and "1I_6 levels of the Tm"3"+ ion deduced from the spectra was analysed according to the C_4_v point symmetry of the RE"3"+ site. The resulting energy level scheme, consisting of 39 levels (i.e. 55 Stark components) out of the total of 70 (91) for the whole 4f"1"2 configuration, was simulated with the aid of a phenomenological theory taking simultaneously into account both the free-ion and CF effects. The model included 13 adjustable parameters describing the electrostatic (the Racah parameters E_0_-_3) and the configuration interaction (the Trees parameters #alpha#, #beta#, and #gamma#) as well ...

1995-06-26

195

Modification of ion-exchange resin composition for the removal of gadolinium from moderator system of 540 MWe PHWRs  

International Nuclear Information System (INIS)

Gadolinium removal during the first approach to criticality of TAPP-4 540 MWe reactor using mixed bed resin (strong acid cation resin and weak base anion resin) topped with strong acid cation exchange resin yielded IX column outlet pH of >6 during the first 6 h of run during which [Gd] decreased from 2.1 to 1 mg/kg. However, the main moderator system pH was between 5.0-5.5. Technical specification for pH of moderator is in the range 5.0-5.5 as long as Gd is present. This is to avoid any precipitation of Gd in the core and a pH of 5.8 or even a pH of 5.6 when carbonate is present is specified as the upper limit of the moderator system pH for this purpose. The situation of IX column outlet pH being #>=# 6 mixing with a system water having Gd results in local mixing zone pH in the range of 6- 5.4. In order to have an iso-pH regime (5-5.5) both with respect to the IX outlet as well as in the system, studies were conducted to modify IX resin composition. Use of ...

2005-11-01

196

Measurement of K x-ray intensity ratio of tin, gadolinium and dysprosium  

International Nuclear Information System (INIS)

Full text: Measurement of K_#beta# to K_#alpha# x-ray intensity ratios are important not only in the field of atomic physics, radiation physics and medical physics, but also to test the validity of assumptions made in the theoretical prediction. The intensity ratios can also give information on the effect of physical and chemical environment of the element in the compound. Many investigators have adopted a single and double reflection geometries to measure the K_#beta# to K_#alpha# x ray intensity ratios to understand the effect of physical and chemical environment on x-ray fluorescence. The targets are excited by a radioactive source of having activity of the order 100 MBq. in order to carry out accurate measurement K_#beta# to K_#alpha# x-ray intensity ratios, we have develop 2#pi# geometrical configuration method : placing a target right on the surface of the detector facing the target to measure the K shell fluorescence parameters such as fluorescence yield, fluorescence cross ...

2003-11-01

197

A large surface neutron and photon detector for civil security applications  

Energy Technology Data Exchange (ETDEWEB)

The security of ports and transportation is of utmost importance for the development of economy and the security of a nation. Among the necessary actions to ensure the security of ports and borders, the inspection of containers is one of the most time consuming and expensive procedures. Potential threats are the illegal traffic of radioactive materials that could be employed for the construction of weapons, as uranium and plutonium. New techniques for the inspections of containers should be fast, allow the detection and identification of dangerous materials, and be non-invasive, to reduce costs and delays. We propose to build a large surface photon and neutron detector based on plastic scintillator to identify the presence of fissile or fertile material inside a container. The detector consists of scintillator bars, wrapped in thin foils of reflecting material containing gadolinium for neutron capture and arranged in planes separated by few-millimeter-thick lead ...

2010-05-21

198

A large surface neutron and photon detector for civil security applications  

International Nuclear Information System (INIS)

The security of ports and transportation is of utmost importance for the development of economy and the security of a nation. Among the necessary actions to ensure the security of ports and borders, the inspection of containers is one of the most time consuming and expensive procedures. Potential threats are the illegal traffic of radioactive materials that could be employed for the construction of weapons, as uranium and plutonium. New techniques for the inspections of containers should be fast, allow the detection and identification of dangerous materials, and be non-invasive, to reduce costs and delays. We propose to build a large surface photon and neutron detector based on plastic scintillator to identify the presence of fissile or fertile material inside a container. The detector consists of scintillator bars, wrapped in thin foils of reflecting material containing gadolinium for neutron capture and arranged in planes separated by few-millimeter-thick lead ...

2010-05-11

199

Modern imaging methods for diagnostic evaluation of tumors of the oropharynx and the oral cavity; Moderne bildgebende Methoden bei der Diagnostik von Tumoren des Oropharynx und der Mundhoehle  

Energy Technology Data Exchange (ETDEWEB)

Differentiating a benign from a malignant lesion by information such as density data, or signal intensities or echo gradients, is not possible with CT, nor MRI, nor ultrasonography. Only some lesions show characteristic signs. Inflammations cannot be difscriminated from malignant tumors. CTs of small tumors in particular are so poor in contrast that it is much more difficult to detect tumors or discriminate them from other lesions, as compared to MR images or ultrasonographs. CT does not detect surface tumors, but is more sensitive than MRI or US in detecting discrete cortical bone lesions. The same applies to small calcified tumors. MRI however is most sensitive in detecting tumor volumes in the yellow marrow, and is the best modality for evaluation of extraossal extension of tumors. CT yields better results than MRI if applied for simultaneous screening of lymph node metastases in the lower neck. MRI frequently is spoilt by movement artefacts. High-resolution, ...

1996-11-01

200

Diagnosis of plasmocytomas using magnetic resonance imaging; Diagnostik des Plasmozytoms mit der MRT  

Energy Technology Data Exchange (ETDEWEB)

Background. In multiple myeloma 5 different infiltration patterns can be differentiated: 1. Normal appearance of bone marrow, 2. focal involvement, 3. homogeneous diffuse infiltration, 4. combined diffuse and focal infiltration, 5. 'salt-and pepper' pattern with inhomogeneous bone marrow with interposition of fat islands. Methods. For the fast and total acquisition of all patterns a combination of a T1-weighted spin echo sequence and a fat suppression technique is superior. The focal involvement is clearly demonstrated as areas of high signal intensity on e.g. STIR images. Diffuse involvement can be quantified objectively by calculation of the percentage of signal intensity increase after contrast material injection. MRI is superior to X-ray in focal and diffuse involvement. With ultrafast sequences a 'screening' of the whole red bone marrow as for myeloma infiltration is possible. Prognosis. In prognosis studies diffuse ...

2000-08-01

202

The Use of Medical Images in Planning and Delivery of Radiation Therapy  

UK PubMed Central (United Kingdom)

Abstract The authors provide a survey of how images are used in radiation therapy to improve the precision of radiation therapy plans, and delivery of radiation treatment. In contrast...Full Text Available

1997-09-01

203

Symbiotic regulation of plant growth, development and reproduction  

UK PubMed Central (United Kingdom)

The growth and development of rice (Oryzae sativa) seedlings was shown to be regulated epigenetically by a fungal endophyte. In contrast to un-inoculated (nonsymbiotic) plants, endophyte...Full Text Available

2009-03-01

204

Physiological and Biochemical Variations during the Molt Cycle in Juvenile Litopenaeus vannamei under Laboratory ...  

Science.gov (United States)

... 05). In contrast with the information available for Penaeus monodon Fabricius, 1798 (Ferraris et al., 1987) and L. vannamei ( ... ...

205

Interaction of legionella pneumophila and helicobacter pylori with bacterial species isolated from drinking water biofilms  

UK PubMed Central (United Kingdom)

BackgroundIt is well established that Legionella pneumophila is a waterborne pathogen; by contrast, the mode of Helicobacter pylori transmission...Full Text Available

206

Double plasma mirror for ultrahigh temporal contrast ultra-intense laser pulses  

International Nuclear Information System (INIS)

We present and characterize a very efficient optical device that employs the plasma mirror technique to increase the contrast of high-power laser systems. Contrast improvements higher than 104 with 50% transmission are shown to be routinely achieved on a typical 10 TW laser system when the pulse is reflected on two consecutive plasma mirrors. Used at the end of the laser system, this double plasma mirror preserves the spatial profile of the initial beam, is unaffected by shot-to-shot fluctuations, and is suitable for most high peak power laser systems. We use the generation of high-order harmonics as an effective test for the contrast improvement produced by the double plasma mirrors. (authors)

207

Digital subtraction angiography with scanning lazer stimulated luminescence  

International Nuclear Information System (INIS)

Fuji Computed Radiography (FCR) utilizes imaging plates of scanning lazer stimulated luminescence. FCR can be used for intravenous digital subtraction angiography (IVDSA) and for intraarterial studies because of tis high contrast and spatial resolution. Pixel size of the imaging plates for angiography is 0.2 mm. Experimentally, it could demonstrate a vessel 1 mm in diameter with a contrast of 0.1, when opacified with a contrast medium of 3 % iodine concentration, and could image a vessel 3 mm in diameter with contrast of 0.1, when opacified with 1 % contrast medium. A 20 % stenosed portion of a vessel 3 mm in diameter was identified when opacified with 3 % contrast medium, and a 20 % stenosed portion of a vessel 2 mm in diameter was identified when opacified with 10 % contrast medium. In 105 IVDSA examinations of 75 patients, FCR was ...

1985-01-01

208

Contrast Sensitivity and Optical Quality of the Eye after Instillation of Timolol Maleate Gel-Forming Solution and Brinzolamide Ophthalmic Suspension  

British Library Electronic Table of Contents (United Kingdom)

Purpose To investigate the influence of timolol maleate 0.5% gel-forming solution and brinzolamide 1% ophthalmic suspension on contrast sensitivity, ocular higher-order aberration (HOA), and corneal surface light scattering. Design Prospective, comparative study. Participants Forty normal volunteers were enrolled in this study. Methods We evaluated contrast sensitivity, ocular HOA, and corneal light scattering before and 2, 5, 10, and 15 minutes after instillation of antiglaucoma eyedrops. Contrast sensitivity function was assessed with the CSV-1000RN chart (Vector Vision Co., Greenville, OH). Higher-order aberration was measured for a 4-mm pupil using the Hartmann-Shack aberrometer (KR-9000PW; Topcon, Tokyo, Japan). Corneal surface light scattering was quantitatively evaluated by using th...

2010-01-01

209

Chronic kidney disease in children: the global perspective  

UK PubMed Central (United Kingdom)

In contrast to the increasing availability of information pertaining to the care of children with chronic kidney disease (CKD) from large-scale observational and interventional studies, epidemiological...Full Text Available

2007-12-01

210

Cancer as a metabolic disease  

UK PubMed Central (United Kingdom)

Emerging evidence indicates that impaired cellular energy metabolism is the defining characteristic of nearly all cancers regardless of cellular or tissue origin. In contrast to normal cells, which...Full Text Available

211

10% low density corn-oil emulsion oral contrast agent for abdominal computed tomography  

Energy Technology Data Exchange (ETDEWEB)

CT of the gastrointestinal tract is commonly performed after administration of a high-density diluted iodinated oral contrast material. However, because if inadequate mixing of the contrast material with the gastrointestinal contents, pseudotumor and poor mucosal visualization are frequently shown on abdominal CT. To overcome these problem, 10% corn oil emulsion (COE) is tested as an alternative oral contrast agent in 40 patients. We analyse patients tolerance, gastric mucosal visualization and discrimination of pancreas from the duodenal C-loop to 10% COE in 40 patients compared with those obtained from 35 patients, who was received high-density diluted iodinated oral contrast agent (gastrografin). The results are as follows : 1. Patients' tolerance to 10% COE is similar to that to conventional oral contrast agent. 2. Image of the gastric mucosa from patients receiving 10% ...

1990-10-15

212

10% low density corn-oil emulsion oral contrast agent for abdominal computed tomography  

International Nuclear Information System (INIS)

CT of the gastrointestinal tract is commonly performed after administration of a high-density diluted iodinated oral contrast material. However, because if inadequate mixing of the contrast material with the gastrointestinal contents, pseudotumor and poor mucosal visualization are frequently shown on abdominal CT. To overcome these problem, 10% corn oil emulsion (COE) is tested as an alternative oral contrast agent in 40 patients. We analyse patients tolerance, gastric mucosal visualization and discrimination of pancreas from the duodenal C-loop to 10% COE in 40 patients compared with those obtained from 35 patients, who was received high-density diluted iodinated oral contrast agent (gastrografin). The results are as follows : 1. Patients' tolerance to 10% COE is similar to that to conventional oral contrast agent. 2. Image of the gastric mucosa from patients receiving 10% COE is ...

1990-10-01

213

Study of silicon damage caused by ultra-low energy boron implantation  

International Nuclear Information System (INIS)

Ultra-shallow junction formation in deep submicron Si devices is limited by anomalous diffusion of the dopant, which is related to the release of interstitials from defect clusters formed during the implantation of energetic ions or the subsequent annealing. The work described in this dissertation is concerned with the effects of low energy B ion implantation, especially damage formation, clustering and its annealing. After a review of the stopping and ranges of energetic ions in Si, the formation of implant damage, in particular of point defects, their migration, agglomeration and annihilation, including the involvement of dopant ions, is considered. A description of the Salford ultra low energy implanter is given and the main analysis technique, medium ion energy scattering (MEIS) reviewed. Additional analytical techniques used, such as secondary ion mass spectrometry (SIMS), 4-point probe and cross section transmission microscopy (XTEM) as well as TRIM simulation are briefly ...

214

Percutaneous US-guided RF thermal ablation for malignant renal tumors: preliminary results in 13 patients  

Energy Technology Data Exchange (ETDEWEB)

Minimally invasive treatment for small renal cell carcinoma (RCC) can be necessary in selected patients and, anyway, is desirable. In situ ablation techniques, including RFA, have been developed. The aim of this study is to evaluate the feasibility, safety and short-term local effectiveness of percutaneous US-guided RFA in a small series, as well as mid-term patient outcome. Thirteen patients with a total of 18 tumors (17 small lesions, 35 mm in size or less, and a larger one, 75 mm in size) underwent 19 RFA sessions. Seven patients had a solitary kidney, and three suffered from VHL disease, too. We treated four lesions in a patient with a bilateral tumor. In another patient, three lesions were ablated. Seventeen tumors were RCC; one was a metastasis from lung cancer. Eight lesions were parenchymal, six exophytic, two parenchymal/exophytic, one parenchymal/central and one central. A monopolar RF system with multitined expandable electrode needles was used. The 35-mm lesion underwent ...

2004-12-01

215

Modern visualization of the liver with MRI - current trends and future perspectives; Moderne Leberbildgebung mit der MRT - aktuelle Trends und Zukunft  

Energy Technology Data Exchange (ETDEWEB)

This contribution provides an overview and imparts basic knowledge on pertinent technical developments in magnetic resonance imaging (MRI) of the liver: 3D sequences, respiratory triggering, parallel imaging, and 3 Tesla (3T). 3D sequences can be used as T1-weighted (T1w) sequences for analyzing dynamics of contrast enhancement or as T2w sequences for MR cholangiography. Consistent improvements in respiratory triggering make it possible to obtain good image quality on T2w scans even in patients unable to hold their breath. Parallel imaging as a universal technique to accelerate image acquisition is particularly appropriate for MRI of the liver, and it has been shown that the reduced acquisition time is not achieved at the expense of image quality. Further progress in MRI of the liver can be expected with use of the 3T systems, but hitherto irrelevant problems must still be solved. Overall the innovations presented here, applied alone or in ...

2004-12-01

216

Magnetic resonance imaging of the urogenital diaphragma in comparison with conventional histomorphological findings (the controversy about the deep transverse muscle of perineum); Kernspintomographische Untersuchungen des Diaphragma urogenitale im Vergleich mit korrespondierenden histomorphologischen Befunden (der Streit um den Misculus transversus perinei profundus)  

Energy Technology Data Exchange (ETDEWEB)

The transversus perinei profundus muscle is a well known structure in found anatomical textbook. Fibres of this muscle are believed to form the so-called external urethral sphincter (musculus sphincter urethrae). Recently histomorphologic investigations have shown that there is no muscular connection between the musculus sphincter urethrae (external sphincter) and the muscle system of the pelvic floor. Furthermore, the external sphincter was found to be divided into parts: The transversely striated part (musculus sphincter urethrae transversostriatus) and the smooth part (musculus sphincter urethrae glaber). Similar to histomorphologic investigations, contrast-enhanced MR imaging has shown the musculus sphincter urethrae to be surrounded by fatty and connective tissue only. Neither in MRI nor in anatomical slices can any connection between the urethral sphincter and the muscle system of the pelvic floor be found. Thus, on the basis of the results presented in this ...

1997-01-01

217

MR imaging guidance and monitoring of focal thermotherapies. A review; Steuerung und Monitoring von fokalen Thermotherapien mit der Magnetresonanztomographie. Ein Ueberblick  

Energy Technology Data Exchange (ETDEWEB)

Minimally invasive thermotherapies for focal tissue destruction on the basis of laser-, microwave-, focused ultrasound-, or cryogeninduced changes of tissue temperature represent an alternative to surgical tissue ablation, particularly in the treatment of tumors. The thermotherapy modalities listed necessitate indirect guidance and monitoring, since they often do not lend themselves to immediate visual control. In the brain, in head and neck tumors, in the liver, and in the prostate, MRI reliably and accurately delineates both the positions of interstitial thermotherapy applicators and - in contrast-enhanced, T1-weighted images - the perfusion defects in tissue necrosis induced by thermotherapy. The transfer of results of in-vitro and in-vivo model studies to assess interstitial temperature and lesion development during thermotherapy to the actual treatment of patients, however, is still in an initial phase. Further development of both rapid MRI sequences and MRI ...

1998-03-01

218

Follicle-stimulating hormone receptor-mediated uptake of "4"5Ca"2"+ by cultured rat Sertoli cells does not require activation of cholera toxin- or pertussis toxin-sensitive guanine nucleotide binding proteins or adenylate cyclase  

International Nuclear Information System (INIS)

We have previously reported that FSH stimulates flux of 45Ca2+ into cultured Sertoli cells from immature rats via voltage-sensitive and voltage-independent calcium channels. In the present study, we show that this effect of FSH does not require cholera toxin (CT)- or pertussis toxin (PT)-sensitive guanine nucleotide binding (G) protein or activation of adenylate cyclase (AC). Significant stimulation of 45Ca2+ influx was observed within 1 min, and maximal response (3.2-fold over basal levels) was achieved within 2 min after exposure to FSH. FSH-stimulated elevations in cellular cAMP paralleled increases in 45Ca2+ uptake, suggesting a possible coupling of AC activation to 45Ca2+ influx. (Bu)2cAMP, however, was not able to enhance 45Ca2+ uptake over basal levels at a final concentration of 1000 microM, although a concentration-related increase in androstenedione conversion to estradiol was evident. Exposure of Sertoli cells to CT (10 ng/ml) consistently stimulated ...

1990-01-01

219

Diagnostic value of apparent diffusion coefficient value in prediction of grade for neuroepithelial tumors  

International Nuclear Information System (INIS)

Objective: To investigate the predictive value of ADC value in grading of neuroepithelial tumors. Methods: The clinical data and images of 70 patients with neuroepithelial tumors pathologically proven were collected and analyzed retrospectively. All the patients were classified into low (WHO I or II) and high (WHO III or IV) grade groups which included 40 and 30 cases respectively according to the 2007 WHO classification of tumours of the central nervous system. All the patients underwent plain and contrast-enhanced MR scan and DWI before surgery. The minimum ADC (MinADC) value was measured postoperatively on ADC maps. The Ki-67 labeling index (Ki-67 LI) of tumor tissue was determined by immunohistochemistry. MinADC values for two groups were analyzed using student t test, while the age and Ki-67 LI for the two groups was analyzed using Mann-Whitney test (P<0.05 considered to be significant). Also the MinADC value and Ki-67 LI were analyzed with Pearson ...

2009-11-01

220

Comparison of high resolution whole-body MRI using parallel imaging and PET-CT. First experiences with a 32-channel MRI system  

International Nuclear Information System (INIS)

To compare the accuracy in the detection and staging of various malignant tumors with high resolution whole-body MRI using parallel imaging with whole-body dual-modality PET-CT. Preliminary results of an interim analysis from a prospective, blinded study are presented, in which 20 patients (mean age 59 years, range 27-77 years) with different oncological diseases underwent whole-body dual modality FDG-PET-CT screening for tumor search or staging in case of confirmed or suspected metastatic disease. All patients also underwent whole-body MRI imaging with the use of parallel imaging (iPAT). High-resolution coronal T1w- and STIR-sequences of 5 body levels with 512 x 512 matrix, axial fast T2w imaging of lung and abdomen (HASTE), contrast-enhanced dynamic and static T1w-sequences of liver, brain, abdomen, and pelvis were performed. Using a 32-channel whole-body MRI scanner (Magnetom Avanto, Siemens Medical Solutions) with a total field of view of 205 cm and free table ...

221

SPIO-enhanced MR angiography for the detection of venous thrombosis in an animal model; SPIO-unterstuetzte MR-Angiographie zur Detektion venoeser Thromben im Tiermodell  

Energy Technology Data Exchange (ETDEWEB)

Purpose: An animal model is used to investigate whether MR angiography combined with super-paramagnetic particles of iron oxide (SPIO) is suitable for detecting thromboses. Methods: 42 rats in groups of 7 each were examined on days 1, 3, 5, 7, 9 and 11, respectively, after mechanical/chemical thrombus induction in a 1.5 Tesla magnet with a FISP sequence (TR/TE/FA 50 ms/6 ms/40 ). Imaging was performed before and up to 90 minutes after intravenous injection of 30 {mu}mol FE/kg BW of the experimental SPIO (hydrodynamic diameter, 34{+-}17 nm LLS; R1 and R2 relaxivity at 0.47 T, 31 and 57 L/(mmol*s)). MIP reconstructions of MR angiographies were submitted to consensus assessment by two examiners using histology as the gold standard. Results: The image quality of MIP reconstructions was rated as good in 38 of 42 cases. With regard to thrombotic vessel occlusion, MR angiography coincided with histology in 17 of 42 cases and differed in 25, lumen narrowing being overestimated by MRI in 4 ...

1999-03-01

222

X-ray dose enhancement effects  

International Nuclear Information System (INIS)

A brief description of the physical process of dose enhancement effects produced by X-ray radiation on materials is given, with emphasis on the influence on electronic devices. The damages caused by X-ray radiation dose enhancement is more serious than that of #gamma#-ray with higher energy.

223

Diabetes Enhances Periodontal Bone Loss through Enhanced Resorption and Diminished Bone Formation  

UK PubMed Central (United Kingdom)

Using a ligature-induced model in type-2 Zucker diabetic fatty (ZDF) rat and normoglycemic littermates, we investigated whether diabetes primarily affects periodontitis by enhancing bone loss...Full Text Available

2006-06-01

224

Deficiency of Phosphoinositide 3-Kinase Enhancer Protects Mice From Diet-Induced Obesity and Insulin Resistance  

UK PubMed Central (United Kingdom)

OBJECTIVEPhosphoinositide 3-kinase enhancer A (PIKE-A) is a proto-oncogene that promotes tumor growth and transformation by enhancing Akt activity. However, the physiological functions...Full Text Available

2010-04-01

225

Multiphasic helical CT of hepatocellular carcinoma. Evaluation after chemoembolization; Tomografia Computerizzata spirale multifasica dell'epatocarcinoma. Valutazione dopo chemioembolizzazione  

Energy Technology Data Exchange (ETDEWEB)

The main purpose of this work is to report the personal experience with addition of contrast-enhanced multiphase helical CT to unenhanced CT (Lipiodol CT) in the evaluation of patients with hepatocellular carcinoma treated with chemoembolization and to analyze the present role of oily agent CT. It has been retrospectively reviewed the examinations of 42 consecutive patients submitted to global chemoembolization over a 2-year period. CT was performed 18-30 days after the treatment. The Lipiodol CT study was carried out with volume acquisitions. It has been considered as nodules all well-defined areas with dense oily agent uptake; uptake itself was classified as: 0=absent, I=lower than 10% of the tumor volume; II=lower than 50%, III=50%, IV=homogeneous. Contrast-enhanced helical CT was performed with the 2-phase technique in 28 patients and with the 3-phase technique in 14; it has been considered as nodules all well-defined and relatively ...

2000-06-01

226

Mathematical Analysis of Three Free-Electron-Laser Issues  

Science.gov (United States)

... iFfficiency-en- enhanced spontaneous radiation at the free-electron- ... as enhanced spontaneous radiation at the free-electron-laser wavelength. ...

1990-09-30

228

Multiple imaging radiography at LNLS  

Energy Technology Data Exchange (ETDEWEB)

An analyzer-based X-ray phase-contrast imaging (ABI) setup has been mounted at the Brazilian Synchrotron Light Laboratory (LNLS) for multiple imaging radiography (MIR) purposes. The algorithm employed for treating the MIR data collected at LNLS is described, and its reliability in extracting the distinct types of contrast that can be obtained with MIR is demonstrated by analyzing a test sample (thin polyamide wire). As a practical application, the possibility of studying ophthalmic tissues, corneal sequestra in this case, via MIR is investigated.

2008-01-11

229

Computer tomographic ventriculography  

Energy Technology Data Exchange (ETDEWEB)

A method for elucidating complex abnormalities of CSF circulation by using a positive contrast medium (metrizamide) and computer tomography is described. The technique for the method, the results and their clinical significance is demonstrated. The value of this method is compared with traditional ventriculography and with computer tomography without the use of contrast medium. It is shown that the technique represents an important extension of the scope of computer tomography.

1982-04-01

230

Wavelength-Dependent Differential Interference Contrast Microscopy: Selectively Imaging Nanoparticle Probes in Live Cells  

Energy Technology Data Exchange (ETDEWEB)

Gold and silver nanoparticles display extraordinarily large apparent refractive indices near their plasmon resonance (PR) wavelengths. These nanoparticles show good contrast in a narrow spectral band but are poorly resolved at other wavelengths in differential interference contrast (DIC) microscopy. The wavelength dependence of DIC contrast of gold/silver nanoparticles is interpreted in terms of Mie's theory and DIC working principles. We further exploit this wavelength dependence by modifying a DIC microscope to enable simultaneous imaging at two wavelengths. We demonstrate that gold/silver nanoparticles immobilized on the same glass slides through hybridization can be differentiated and imaged separately. High-contrast, video-rate images of living cells can be recorded both with and without illuminating the gold nanoparticle probes, providing definitive probe identification. Dual-wavelength ...

2009-11-15

231

Thermal-neutron capture cross section and resonance integral of americium-241  

International Nuclear Information System (INIS)

The thermal-neutron capture cross section (#sigma#_0_,_g) and the resonance integral (I_0_,_g) leading to the ground state of "2"4"2Am were measured by an activation method for neutron capture by "2"4"1Am. A method with gadolinium, which was similar to the cadmium difference method, was used to measure the cross section #sigma#_0_,_g with attention to resonances of "2"4"1Am. Americium chloride samples containing "2"4"1Am radioisotope were irradiated for 68 h in the long-irradiation plug of the Kyoto University Research Reactor, KUR. Wires of Co/Al and Au/Al alloys were used as monitors to determine thermal-neutron fluxes and epithermal Westcott's indexes at the irradiation positions. An #alpha#-ray spectrometer was used to measure the activity ratios of "2"4"2Cm to "2"4"1Am. On the basis of Westcott's convention, the #sigma#_0_,_g and I_0_,_g values were determined as 628#+-#22 b and 3.5#+-#0.3 kb, respectively. (author)

2007-12-01

232

Structural and magnetic properties of barium-gadolinium hexaferrites  

Energy Technology Data Exchange (ETDEWEB)

A series of Gd-substituted M-type barium hexaferrites has been prepared by the ceramic route, according to the formula (Ba{sub 1-x}Gd{sub x})O.5.25Fe{sub 2}O{sub 3} (x=0-0.30). XRD analysis revealed that all the samples present primarily an M-type structure. Samples x=0 and x=0.05 are single-phase. Hematite (Fe{sub 2}O{sub 3}) and GdFeO{sub 3} were detected in the remaining samples. Coercivity (H{sub c}) shows remarkably high values, {approx}293kA/m for x=0.20 and 0.30 with a maximum of 322kA/m for x=0.25. Specific saturation magnetization ({sigma}{sub sat}) of the samples presents a small increase up to x=0.10. The microstructure examination indicates that Gd may act as a grain growth inhibitor.

2007-03-15

233

Structural and magnetic properties of barium-gadolinium hexaferrites  

International Nuclear Information System (INIS)

A series of Gd-substituted M-type barium hexaferrites has been prepared by the ceramic route, according to the formula (Ba_1_-_xGd_x)O.5.25Fe_2O_3 (x=0-0.30). XRD analysis revealed that all the samples present primarily an M-type structure. Samples x=0 and x=0.05 are single-phase. Hematite (Fe_2O_3) and GdFeO_3 were detected in the remaining samples. Coercivity (H_c) shows remarkably high values, #approx#293kA/m for x=0.20 and 0.30 with a maximum of 322kA/m for x=0.25. Specific saturation magnetization (#sigma#_s_a_t) of the samples presents a small increase up to x=0.10. The microstructure examination indicates that Gd may act as a grain growth inhibitor.

2007-03-01

234

Regulatory review of reactor physics design aspects of TAPP-3 and 4  

International Nuclear Information System (INIS)

Atomic Energy Regulatory Board carries out the regulatory review of the reactor physics design, commissioning and operational aspects through Project Design Safety Committee and Specialist Group of reactor physicists with wide experience in the design, commissioning and operational safety review of NPPs. TAPP-3 and 4 PHWRs, being the first indigenous design of 540 MWe Units, are quite different than the standard 220 MWe PHWRs. The safety review of reactor physics design was quite complex, as majority of the systems were new. The Reactor Physics Specialist Group carried out extensive safety review of 540 MWe PHWR reactor physics design and made significant contributions of design modifications and improvements in the operational procedures. Some salient contributions include: Monitoring the core during bulk addition of moderator without the availability of shutdown systems. Logics for providing safety cover in case of malfunction of SDS-1, Use of Gadolinium, ...

2006-11-13

235

Magnetic moment measurements of gadolinium, holmium and ytterbium tartrate trihydrate crystals  

British Library Electronic Table of Contents (United Kingdom)

Magnetic moment and susceptibility of single crystals of rare earth tartrates of the type R(C4H4O6)(C4H5O6)3H2O (where R = Gd, Ho, and Yb), using a vibration sample magnetometer are reported. The experimental values of molar susceptibilities for Gd(C4H4O6)(C4H5O6)3H2O, Ho(C4H4O6)(C4H5O6)3H2O, and Yb(C4H4O6)(C4H5O6)3H2O are 2.58x10-2, 4.66x10-2, and 8.03x10-3 (in cgs em units), respectively. The calculated effective magnetic moments are in good agreement with the theoretical predictions on rare earth ions.

2008-01-01

236

Lifetimes of superdeformed nuclei in the mass region A {approx}150 with the Eurogam multidetector array; Durees de vie de noyaux superdeformes de la region de masse A {approx}150 mesurees avec le multicompteur Eurogam  

Energy Technology Data Exchange (ETDEWEB)

This work concerns the study of the nuclear superdeformation phenomenon in the rare earth region (A {approx} 150). The superdeformed (SD) states in Gadolinium and Dysprosium isotopes were produced via heavy-ion induced reactions and studied with the (EUROGAM EUROpean GAmma-ray Microscope) gamma multidetector array. Precise level attenuation method (DSAM). From the derived quadrupole moments, we find large differences in deformation between the yrast bands in neighbour nuclei explained in terms of the case of nuclei corresponding to an axis ratio of 2:1, the shell gaps are not fixed at a specific particle number and deformation. Furthermore the present results indicate that the deformations associated with identical bands are different supporting the picture that mass and deformation changes tend to compensate in SB bands with the same moments of inertia. (author). 114 refs.

1996-05-13

237

Influence of Ce0.9Gd0.1O2-d particles on microstructure and oxygen permeability of Ba0.5Sr0.5Co0.8Fe0.2O3-d composite membrane  

British Library Electronic Table of Contents (United Kingdom)

This study examined the oxygen permeation behavior of Ce0.9Gd0.1O2-d (Gadolinium-Doped Ceria, GDC)/Ba0.5Sr0.5Co0.8Fe0.2O3-d (BSCF) composite membranes fabricated using a conventional sintering technique. GDC/BSCF composite membranes with a relative density >95% could be obtained when a green compact of BSCF and GDC was sintered at 1150^oC for 5h. It appears that GDC serves as a grain growth inhibitor because the average grain size of the composite decreased with increasing GDC content. The oxygen permeability of the BSCF and GDC/BSCF composite membranes strongly depends on the grain size and membrane thickness. The addition of GDC to BSCF resulted in a small grain size, low thermal expansion coefficient and high hardness. However, it is believed that oxygen permeation was blocked by GDC, a...

2010-01-01

238

Observation and simulation of the energy levels of the trivalent thulium ion in gadolinium oxychloride  

Energy Technology Data Exchange (ETDEWEB)

The optical absorption of the Tm{sup 3+} ion in the gadolinium oxychloride (GdOCl) matrix in the UV, visible, and NIR range was studied at temperatures between 9 and 300 K. The visible luminescence of GdOCl:Tm{sup 3+} under Ar{sup +} ion laser and mercury lamp excitation was recorded at 9, 77, and 300 K, too. The crystal field (CF) splitting of the {sup 3}H{sub 4-6}, {sup 3}F{sub 2-4}, {sup 1}G{sub 4}, {sup 1}D{sub 2}, and {sup 1}I{sub 6} levels of the Tm{sup 3+} ion deduced from the spectra was analysed according to the C{sub 4v} point symmetry of the RE{sup 3+} site. The resulting energy level scheme, consisting of 39 levels (i.e. 55 Stark components) out of the total of 70 (91) for the whole 4f{sup 12} configuration, was simulated with the aid of a phenomenological theory taking simultaneously into account both the free-ion and CF effects. The model included 13 adjustable parameters describing the electrostatic (the Racah parameters E{sub 0-3}) and the ...

1995-06-26

243

Observations of photon echo enhancement in an ultraslow light regime  

CERN Document Server

Using spectral hole-burning-based ultraslow group velocity in a dilute solid medium, we report enhanced photon echo efficiency three orders of magnitude higher than that in a nonslow light regime. The enhancement is due to exponentially increased absorption of an optical data pulse owing to the enhanced photon-atom interaction in an ultraslow light regime, whereas echo reabsorption is negligibly small due to group-velocity dependent population depletion.

2011-01-01

252

Energy conservation via heat transfer enhancement. Quarterly progress report, October 1-December 31, 1979  

Science.gov (United States)

Contacts with researchers, manufacturers, and users of enhanced heat transfer equipment are summarized. The Technical Literature file and the Patent File continue to be updated; the Patent File is the source for a patent technology report now in draft form. Application studies on a rationally-based friction correlation for internally-finned tubes and on the evaluation of candidate tube-side enhancements for OTEC applications are reported. The technology study on enhancement of spray evaporation is also discussed.

1979-01-01

257

Optimum aspect ratio for heat transfer enhancement in curved rectangular channels  

Science.gov (United States)

Enhanced heat transfer in curved rectangular channels depends on at least two geometric factors, the radius of curvature of the duct and the aspect ratio, which is the width/depth ratio of the duct. In this work, an expression for optimum aspect ratio is derived mathematically from a correlation that includes both aspect ratio and bend curvature parameters. Enhancement factors are developed that show optimal, near-optimal, and nonoptimal aspect ratios for curved rectangular ducts. Predicted enhancements are within 25% of published literature results for individual designs, two of which show heat transfer enhancement of 200% over that of a straight duct with turbulent flow. The theoretical maximum enhancement is shown to be about 480% over a straight-duct, turbulent-flow situation. This is not achievable in practice, but near-optimal solutions are achievable, yielding ...

258

Reduction of fluoroscopic exposure for the air-contrast barium enema  

Energy Technology Data Exchange (ETDEWEB)

In a fluoroscopic imaging system, image quality and patient dose are both affected by the optical system linking the image intensifier with the video camera. The effect on patient exposure of increasing the optical iris aperture size over that required for other procedures performed on the same imaging system was investigated for the air-contrast barium enema examination. Using a large-area transmission ionisation chamber to monitor the Roentgen-area-product of entrance exposure, a decrease in fluoroscopic radiation of greater than 50% was clinically documented for a fluoroscopic system utilising kVp and mA variable automatic brightness control. For this iris change, the video image was of acceptable quality for positioning and monitoring the patient, and no deleterious effect was detected in the conduct of the air-contrast exam. The availability of a variable-sized operator-selectable iris diaphragm would permit this dose-reduction approach to ...

1983-11-01

259

Magnetization transfer contrast effect on multislice fast spin echo  

Energy Technology Data Exchange (ETDEWEB)

Magnetization transfer contrast (MTC) on fast spin echo (FSE) images was evaluated in normal brain tissue as well as in brain tumors to better understand contrast of FSE images. On multislice FSE images, attenuation of the signal intensity of brain tissue due to MTC is observed. The rate of MTC (MTR) is obtained by comparing with additional single slice images. The effect of signal attenuation is greater on images with smaller interslice gap, larger number of slices, and longer echo train length. MTR of brain tumors is less than that of normal brain tissue. Among them, meningiomas have relatively high MTR, and cavernous malformation has relatively low MTR. Determination of MTC can be easily specified by obtaining multislice and single slice FSE images, and it may help differentiate brain tumors. (author).

1994-03-01

260

Low-dose contrast protocol using the test bolus technique for 64-detector computed tomography coronary angiography  

British Library Electronic Table of Contents (United Kingdom)

Purpose We evaluated low-contrast injection protocols for coronary computed tomography angiography (CTA) using a 64-detector scanner and the test bolus technique. Materials and methods We randomly assigned 60 patients undergoing coronary CTA to one of two contrast material (CM) injection protocols. For the lowcontrast dose protocol (Plow), the patients received injections of iohexol-350 [0.7 ml/kg body weight (BW)] during 9 s, and the test-bolus technique was used. Under the conventional protocol (Pconv), they received iohexol-350 (1.0 ml/kg BW) during 15 s, and bolus tracking was used. We compared the protocols for attenuation values in the ascending aorta and coronary arteries and for the amount of CM required. Results There was no significant difference in the mean CT attenuation of the...

2011-01-01

261

Diagnostic quality in hysterosalpingography  

International Nuclear Information System (INIS)

Purpose: To compare the diagnostic quality and adverse events of the water-soluble, non-ionic, iso-osmolar, dimeric contrast media iodixanol and iotrolan in hysterosalpingography (HSG). Material and Methods: One hundred and twenty patients participated in a double-blind randomized parallel-group phase-III study. Questionnaires and patient interviews were used. Diagnostic quality was assessed using a visual analogue scale and the quality in specific regions was rated using a categorical scale. Results: Overall diagnostic quality was equal for the two groups. There was no statistically significant difference between the two groups in diagnostic quality in the specific regions of interest. No differences between the contrast media were found with regard to adverse events. Conclusion: Both contrast media provided images of high diagnostic quality in HSG. (orig.)

1998-11-01

262

Contrast material extravasation following upper abdominal trauma. Detection with helical Computerized Tomography  

International Nuclear Information System (INIS)

Active contrast material extravasation can be recognized with conventional CT scanners, though it has been considered a rare finding. Helical CT seems to increase the detection rate and especially to boost the radiologist's confidence in this diagnosis. Though active bleeding is defined in severely-injured subjects requiring urgent intervention and may be associated with findings of hypovolaemic shock, it should not be considered itself as a negative prognostic factor. Contrast extravasation is due to ongoing hemorrhage and its detection is critical for urged treatment. Accurate anatomical location permits to choose surgical management or transcatheter embolization and thus decreases time consumption for precis e bleeding site identification.

1999-03-01

263

Are the delay images necessary to evaIuate the liver metastatic lesions on mangafodipir trisodium enhanced liver MRI?: comparison with hepatocellular carcinomas  

Energy Technology Data Exchange (ETDEWEB)

To assess whether ring enhancements of liver metastases on Mn-DPDP enhanced, early MR images were well visualized on delayed images, as compared with those of hepatocellular carcinomas (HCC), and to investigate the detection accuracy and conspicuity of each tumor. Twenty patients with liver metastases and 15 with HCC were studied by Mn-DPDP enhanced, T1-weighted MR images. Peripheral ring enhancement and conspicuity were investigated. Differences in detection accuracy and frequency of ring enhancement in liver metastases and HCC were assessed. In liver metastases (n= 69), 44 cases (63.8%) without ring enhancement and 25 (36.2%) with were noted on early images. Sixteen cases (23.2%) without ring enhancement, 38 (55.1%) with ring enhancement similar to the early images, and 15 (21.7%) with prominent ring ...

2004-09-01

264

Correlation of Multislice CT and Histomorphology in HCC Following TACE: Predictors of Outcome  

Science.gov (United States)

The purpose of this study was to correlate histopathological with CT findings in patients suffering from hepatocellular carcinoma (HCC) eligible for orthotopic liver transplantation (OLT), with a special focus on the antitumoral effect of transarterial chemoembolization (TACE) therapy. A total of 42 consecutive patients suffering from HCC had been treated prior to OLT by means of TACE. TACE was carried out with a mixture of Lipiodol (10-20 ml) and mitomycin C (max. dosage, 10 mg). TACE was performed at 6- to 8-week intervals. Follow-up investigation included contrast-enhanced multislice CT controls and laboratory control. Liver explants were evaluated macroscopically and microscopically to determine the number and size of the tumor lesions as well as the degree of tumor necrosis. Necrosis was investigated in H and E-stained sections. The degree of necrosis was classified as follows: 0-25%, 26-50%, 51-75%, 75-99%, and complete necrosis. Two hundred thirty-one TACE ...

2008-07-15

265

The zebrafish heart regenerates after cryoinjury-induced myocardial infarction  

UK PubMed Central (United Kingdom)

BackgroundIn humans, myocardial infarction is characterized by irreversible loss of heart tissue, which becomes replaced with a fibrous scar. By contrast, teleost fish and urodele...Full Text Available

266

The Oxidation Behavior of CoCrAlY, CoCrAl and Yttrium ...  

Science.gov (United States)

... ADD137758. Title : The Oxidation Behavior of CoCrAlY, CoCrAl and Yttrium-Implanted CoCrAl Alloys Compared and Contrasted,. ...

1987-11-01

267

Synthesis and characterization of PVP-coated large core iron oxide nanoparticles as an MRI contrast agent  

UK PubMed Central (United Kingdom)

The purpose of this study was to synthesize biocompatible polyvinylpyrrolidone (PVP)-coated iron oxide (PVP-IO) nanoparticles and to evaluate their efficacy as a magnetic resonance imaging (MRI)...Full Text Available

2008-04-01

268

Squamous Cell Carcinoma in South-Eastern Equatorial Rain Forest in Calabar, Nigeria  

UK PubMed Central (United Kingdom)

Background: In North America and Europe, 80% of invasive skin cancers are basal cell carcinoma while 20% are squamous cell carcinoma (SCC). In contrast, African studies reveal a preponderance...Full Text Available

269

STRUCTURE OF THE MACULA UTRICULI WITH SPECIAL REFERENCE TO DIRECTIONAL INTERPLAY OF SENSORY RESPONSES AS REVEALED BY MORPHOLOGICAL POLARIZATION  

UK PubMed Central (United Kingdom)

The anatomy of the labyrinth and the structure of the macula utriculi of the teleost fish (burbot) Lota vulgaris was studied by dissection, phase contrast, and electron microscopy....Full Text Available

1964-08-01

270

Pulmonary toxicity and carcinogenicity of trichloroethylene: species differences and modes of action.  

UK PubMed Central (United Kingdom)

Trichloroethylene (TCE) is both acutely toxic and carcinogenic to the mouse lung following exposure by inhalation. In contrast, it is not carcinogenic in the rat lung and is markedly less toxic following...Full Text Available

2000-05-01

271

Of mice and rats: key species variations in the sexual differentiation of brain and behavior  

UK PubMed Central (United Kingdom)

Mice and rats are important mammalian models in biomedical research. In contrast to other biomedical fields, work on sexual differentiation of brain and behavior has traditionally utilized comparative...Full Text Available

2010-07-01

272

New strain of mouse hepatitis virus as the cause of lethal enteritis in infant mice.  

UK PubMed Central (United Kingdom)

A new strain of mouse hepatitis virus (MHV) was isolated from pooled gut suspensions from an epizootic of lethal enteritis in newborn mice. Negative-contrast electron microscopy showed an abundance...Full Text Available

1979-05-01

273

MR imaging of bone marrow with gradient echo sequences. Pt. 1. Contrast conditions of phase-identical and opposed-phase gradient echo sequences. Kernspintomographische Screeninguntersuchungen des Knochenmarkes mit Gradientenecho-Sequenzen. T. 1. Kontrastverhaeltnisse phasenidentischer und phasenverschobener Gradientenecho-Sequenzen. Untersuchungen von Probanden und pathologisch-anatomischen Praeparaten  

Energy Technology Data Exchange (ETDEWEB)

Anatomical specimens and normal persons were studied by gradient echo MR imaging to determine the influence of different echo times (TE) on bone marrow contrast. First of all, six normal persons were studied to determine specific echo times for in-phase and opposed-phase states. Using different sequences bone marrow contrast in isolated femoral bones was determined and compared to results of pathological exams. Red bone marrow had no signal on opposed-phase images; contrast between red and yellow marrow was higher on opposed-phase than on in-phase images. Bone marrow lesions can be expected to be visualised with high signal on opposed-phase images; this technique should be especially suited for MR imaging of bone marrow. (orig.).

1991-06-01

274

Longitudinally and circumferentially directed movements of the left ventricle studied by cardiovascular magnetic resonance phase contrast velocity mapping  

UK PubMed Central (United Kingdom)

ObjectiveUsing high resolution cardiovascular magnetic resonance (CMR), we aimed to detect new details of left ventricular (LV) systolic and diastolic function, to explain the twisting...Full Text Available

275

Kinetic Complexity of the Global Response to Glucocorticoid Receptor Action  

UK PubMed Central (United Kingdom)

We have characterized the kinetic response of gene targets throughout the murine genome to transcriptional modulation by the glucocorticoid receptor (GR). In contrast to a model in which multiple genes...Full Text Available

2009-04-01

276

Increased expression of cytosolic chaperonin CCT in human hepatocellular and colonic carcinoma  

Science.gov (United States)

... protein is abundant in cytosolic portions of malignant epithelial tissue (Fig. 3A). In contrast, the degree of CCTβ staining in normal epithelial tissue (Fig. 3B) or connective tissues was much weaker ......

277

Expansions, contractions, and fragility of the spinocerebellar ataxia type 10 pentanucleotide repeat in yeast  

UK PubMed Central (United Kingdom)

Spinocerebellar ataxia 10 (SCA10) is an autosomal dominant disease caused by large-scale expansions of the (ATTCT)n repeat within an intron of the human ATXN10 gene. In contrast...Full Text Available

2011-02-15

278

Evaluation of Tumor Micro-Environment in an Animal Model using a Nanoparticle Contrast Agent in Computed Tomography Imaging  

UK PubMed Central (United Kingdom)

RATIONALE AND OBJECTIVESNon-invasive longitudinal imaging of tumor vasculature could provide new insights into the development of solid tumors, facilitating efficient...Full Text Available

2011-01-01

279

Evaluation of Oral Administration of Adenine to Dogs and Primates.  

Science.gov (United States)

Little change was observed in primates fed 75 mg/kg adenine over the four-week period. Minimal tissue pathology was encountered upon completion of the study. In contrast to earlier studies in which oral feeding of adenine to dogs caused severe symptoms, a...

1974-01-01

280

Effect of Edge-Preserving Adaptive Image Filter on Low-Contrast Detectability in CT Systems: Application of ROC Analysis  

UK PubMed Central (United Kingdom)

Objective. For the multislice CT (MSCT) systems with a larger number of detector rows, it is essential to employ dose-reduction techniques. As...Full Text Available

2008-01-01

281

Dual Energy and Low kVp CT in the Abdomen  

UK PubMed Central (United Kingdom)

Low kVp settings provide high conspicuity of contrast materials at CT but may result in high image noise, particularly in larger patients. Material decomposition at dual energy CT can differentiate...Full Text Available

2009-07-01

282

Dimeric subunit stoichiometry of the human voltage-dependent proton channel Hv1  

UK PubMed Central (United Kingdom)

In voltage-gated Na+, K+, and Ca2+ channels, four voltage-sensor domains operate on a central pore domain in response to membrane voltage. In contrast, the voltage-gated...Full Text Available

2008-06-03

283

Differing in vitro Survival Dependency of Mouse and Rat NG2+ Oligodendroglial Progenitor Cells  

UK PubMed Central (United Kingdom)

NG2 chondroitin sulfate proteoglycan is a surface marker of oligodendroglial progenitor cells (OPCs) in various species. In contrast to well-studied rat OPCs, however, we found that purified...Full Text Available

2010-04-01

284

Development of melanopsin-based irradiance detecting circuitry  

UK PubMed Central (United Kingdom)

BackgroundMost retinal ganglion cells (RGCs) convey contrast and motion information to visual brain centers. Approximately 2% of RGCs are intrinsically photosensitive (ipRGCs), express...Full Text Available

285

Cross-sectional Specimen Preparation and Observation of a Plasma Sprayed Coating Using a Focused Ion Beam/Transmission Electron Microscopy System.  

Science.gov (United States)

A focused ion beam (FIB) technique was applied to cross-sectional specimen preparation to observe an interface between a plasma sprayed coating and an aluminum (Al) substrate by transmission electron microscopy (TEM). The surface of the sprayed coating film has a roughness of several tens of microns. Sputter rates for the coating film and the substrate are greatly different. The rough surface and the difference in sputter rate cause problems in making TEM specimens with smooth side walls. The top surface of the coating film was planerized by the FIB before fabricating the TEM specimen. The interfaces were investigated by TEM and energy-dispersive X-ray (EDX) analysis. The TEM observation revealed that there is a 10 nm thick amorphous layer at the interface between the coating film and substrate. The coating film consists of two kinds of sublayers with bright and dark contrast. The bright contrast sublayers were amorphous layers with thickness ...

2000-05-01

286

Contrasting Population Structures of the Genes Encoding Ten Leading Vaccine-Candidate Antigens of the Human Malaria Parasite, Plasmodium falciparum  

UK PubMed Central (United Kingdom)

The extensive diversity of Plasmodium falciparum antigens is a major obstacle to a broadly effective malaria vaccine but population genetics has rarely been used to guide vaccine design....Full Text Available

287

Comparing and Contrasting the Roles of AMPK and SIRT1 in Metabolic Tissues  

UK PubMed Central (United Kingdom)

The ability to adapt and respond to nutrients is an ancient cellular function, conserved from unicellular to the most complex multicellular organisms, including mammals. Mammals adapt to changes...Full Text Available

2008-12-01

288

Comparative aspects of cortical neurogenesis in vertebrates  

UK PubMed Central (United Kingdom)

The mammalian neocortex consists of six layers. By contrast, the reptilian and avian cortices have only three, which are believed to be equivalent to layers I, V and VI of mammals. In mammals, the majority...Full Text Available

2007-08-01

289

Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study  

UK PubMed Central (United Kingdom)

Partial epilepsies have a substantial heritability. However, the actual genetic causes are largely unknown. In contrast to many other common diseases for which genetic association-studies have successfully...Full Text Available

2010-07-01

290

Colour television, an imitation of the human visual system.  

UK PubMed Central (United Kingdom)

Colour television is examined as an attempt to imitate the human visual system in image formation, spectral sensitivities, adaptation, contrast effects, signal processing, signal modulation, signal...Full Text Available

1975-07-01

291

Bimodal MR-PET agent for quantitative pH imaging  

UK PubMed Central (United Kingdom)

Activatable or “smart” magnetic resonance contrast agents have relaxivities that depend on environmental factors such as pH or enzymatic activity, but the MR signal depends on...Full Text Available

2010-03-22

292

Alteration of the chemical environment disrupts communication in a freshwater fish  

UK PubMed Central (United Kingdom)

It is well established that changes to the chemical environment can impair development, physiology and reproductive biology; by contrast, impacts on communication have not been widely reported. This...Full Text Available

2006-05-22

293

Age-Related Deterioration of Rod Vision in Mice  

UK PubMed Central (United Kingdom)

Even in healthy individuals, aging leads to deterioration in visual acuity, contrast sensitivity, visual field, and dark adaptation. Little is known about the neural mechanisms that drive the...Full Text Available

2010-08-18

294

Cerebral angiography using Fuji computed radiography (FCR) system  

International Nuclear Information System (INIS)

Eighty-seven subtraction images of FCR were compared with subtraction images of conventional angiography. Although FCR images with reduced exposure dose (25 % of regular dose) and with diluted contrast material (150 mgI/ml, 50 % of usual concentration) were slightly inferior to the images of conventional angiography, most clinically important vessels were adequately visualized. As FCR has wider dynamic range and higher contrast resolution than conventional angiography, FCR may take over conventional angiography. (author).

1985-01-01

295

Diffusion modeling of ion implanted boron in Si during RTA: Correlation of extended defect formation and annealing with the enhanced diffusion of boron  

International Nuclear Information System (INIS)

Accurate modeling of the enhanced diffusion of boron during rapid thermal annealing has been accomplished by incorporating the effects of extended defect formation and annealing on enhanced diffusion into a multizone, semiempirical model. The multizone model divides the implant profile into three zones defining regions of different defects and diffusion enhancements. The model also contains the initial enhanced diffusion and the transient diffusion effects associated with the dissolution of defect clusters and the annealing of extended defects, respectively. The saturation time for transient-enhanced diffusion contains an exponential function of implant dose in order to model the increase in point defect generated with higher implant dose. As a result, the model accurately simulates the boron diffusion profile over a wide range of implant doses and also shows the immobile boron peak ...

296

When Top-Down Meets Bottom-Up: Auditory Training Enhances Verbal Memory in Schizophrenia  

UK PubMed Central (United Kingdom)

A critical research priority for our field is to develop treatments that enhance cognitive functioning in schizophrenia and thereby attenuate the functional losses associated with the illness. In this...Full Text Available

2009-11-01

297

Transposons as tools for enhancer trap screens in vertebrates  

UK PubMed Central (United Kingdom)

DNA transposons are efficient tools in transgenesis and have therefore become popular in the analysis of the regulatory genome in vertebrates via enhancer trap screens. Here, I discuss recent progress...Full Text Available

2007-01-01

298

The Differing Impact of Multisensory and Unisensory Integration on Behavior  

UK PubMed Central (United Kingdom)

Pooling and synthesizing signals across different senses often enhances responses to the event from which they are derived. Here we examine whether multisensory response enhancements are attributable...Full Text Available

2009-04-15

299

Resonance Raman enhancement of phenyl ring vibrational modes in phenyl iron complex of myoglobin.  

UK PubMed Central (United Kingdom)

Resonance Raman spectra are reported for the organometallic phenyl-FeIII complexes of horse heart myoglobin. We observed the resonance enhancement of the ring vibrational modes of the bound phenyl group....Full Text Available

1990-04-01

300

Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity  

UK PubMed Central (United Kingdom)

How transcription factors interpret the cis-regulatory logic encoded within enhancers to mediate quantitative changes in spatiotemporally restricted expression patterns during animal...Full Text Available

2010-05-15

301

Plasma Treatment of Surfaces and Plasma Enhanced Deposition.  

Science.gov (United States)

This report results from a contract tasking Eindhoven University of Technology as follows: The contractor will investigate the plasma treatment of surfaces and plasma enhanced deposition using EUT's cascade arc source as the basis for this effort.

1997-01-01

302

Molecular biological enhancement of coal biodesulfurization. Final report, October 1988--December 1991  

Energy Technology Data Exchange (ETDEWEB)

The overall objective of this project was to use molecular genetics to develop strains of bacteria with enhanced ability to remove sulfur from coal, and to obtain data that will allow the performance and economics of a coal biodesulfurization process to be predicted. (VC)

1991-12-01

303

K Kiosk - NIH Extramural Training: Information about NIH Career...  

Science.gov (United States)

Established Investigators (K18) (PAR-09-090) NIH: Career Enhancement Award for Stem Cell Research (K18) (PA-09-110) NIDCD: NIDCD Research Career Enhancement Award for Established...

2011-10-01

304

Image-Guided Convection-Enhanced Delivery Platform in the Treatment of Neurological Diseases  

UK PubMed Central (United Kingdom)

SummaryConvection-enhanced delivery (CED) of substances within the human brain is becoming a more frequent experimental treatment option in the management of brain tumors, and...Full Text Available

2008-01-01

305

Heat Stress Enhances the Accumulation of Polyadenylated Mitochondrial Transcripts in Arabidopsis thaliana  

UK PubMed Central (United Kingdom)

BackgroundPolyadenylation of RNA has a decisive influence on RNA stability. Depending on the organisms or subcellular compartment, it either enhances transcript stability or targets...Full Text Available

306

Convection-enhanced delivery of maghemite nanoparticles: Increased efficacy and MRI monitoring  

UK PubMed Central (United Kingdom)

Convection-enhanced drug delivery (CED) is a novel approach to delivering drugs into brain tissue. Drugs are delivered continuously via a catheter, enabling large volume distributions of high drug concentrations...Full Text Available

2008-04-01

307

Wideband Modulation and Tuning of Semiconductor Lasers ...  

Science.gov (United States)

... Tunable semiconductor lasers are essential components for links employing optical frequency modulation (OFM) for enhanced dynamic range or ...

1996-07-01

308

Tests of Turbulators for Fire-Tube Boilers.  

Science.gov (United States)

... Originator-supplied keywords include: Turbulators, Heat transfer augmentation, Enhancement, Fire tube boilers. (Author). ...

1982-10-01

309

Selective enhancement of barium in the atmospheres of red giants  

Energy Technology Data Exchange (ETDEWEB)

High-resolution spectroscopy of 13 bright red giants and Ba stars shows selective enhancement of Ba in three of them, HD 65699 (Ba 2), ..cap alpha..TrA (K4 III), and epsilonPeg (K2 Ib). Infrared spectra available for HD 65699 show that Sr is enhanced, too. This selective enhancement is discussed in terms of a modified s-process which converts some of the pre-existing r- and s-process matter into the magic nuclei /sup 88/Sr and /sup 138/Ba.

1984-03-01

310

Research workshop on energy conservation through enhanced heat transfer  

Science.gov (United States)

Seven papers were presented at the meeting. A separate abstract was prepared for each paper. (LCL)

1979-10-01

312

Package Enhancement Study for the 120-mm M831E2 ...  

Science.gov (United States)

... Descriptors : *AMMUNITION, *CONTAINERS, *CARTRIDGES, *COMBUSTIBLE CARTRIDGE CASES, *CARTRIDGE CASES, *ANTITANK ...

1992-07-01

313

Nuclear forensics. The science for enhancing nuclear security  

International Nuclear Information System (INIS)

Japanese ... Authors Kuno, Yusuke; Esaka, Konomi (Tokyo Univ., Graduate School of Engineering, Tokyo (Japan))

2011-01-01

315

Human Auditory Localization Performance in Azimuth  

Science.gov (United States)

... The realization of directional audio technology in the cockpit may reduce visual workload, enhance the presentation of flight and threat information ...

1991-01-01

319

Enhanced Core Noise Modeling for Turbofan Engines  

Science.gov (United States)

This report describes work performed by MTC Technologies (MTCT) for NASA Glenn Research Center (GRC)

2011-01-01

321

Combating Terrorism and Enhancing Regional Stability and ...  

Science.gov (United States)

... Uninterrupted access to and use of critical infrastructure in the Arabian Gulf region are key to the successful prosecution of the Global War on Terror ...

2004-11-01

323

Transient enhanced diffusion and deactivation of ion-implanted As in strained Si  

International Nuclear Information System (INIS)

First results on the effects of strain on transient enhanced diffusion and deactivation of As-implanted ultrashallow junctions are presented. A significant effect of strain on the magnitude and timescale of transient enhanced diffusion is observed, which is consistent with the stabilization of interstitial-type defects by tensile strain. Our results show no significant impact of strain on As electrical activity during the deactivation timescale accessed in this study.

2005-08-01

324

The enhancement of three-party simultaneous quantum secure direct communication scheme with EPR pairs  

Science.gov (United States)

Recently, Wang et al. proposed a three-party simultaneous quantum secure direct communication (3P-SQSDC) scheme with EPR pairs, which enables three involved parties to exchange their secret messages simultaneously by using an EPR pair. This work proposed an enhancement on Wang et al.'s scheme. With the enhancement, the communications in the improved 3P-SQSDC can be paralleled and thus improves the protocol efficiency.

2011-01-01

325

Study of transient enhanced dopant diffusion in silicon and proposed limiting methods  

International Nuclear Information System (INIS)

The transient enhanced diffusion in crystalline silicon implanted with dopants ad followed by high temperature annealing to activate the dopants is introduced. The physical mechanisms of transient enhanced dopant diffusion are then reviewed together with a short introduction to the proposed suppressing methods. Finally, the perspectives with using high energy heavy ions in this field are briefly discussed

2001-09-01

326

On the theory of transient enhanced diffusion in boron-implanted silicon  

Energy Technology Data Exchange (ETDEWEB)

Transient enhanced diffusion in boron-implanted silicon is interpreted as being due to the fact that during rapid thermal annealing a relaxation process takes place, associated with quasi-chemical reactions including defects. A simple analytical model makes it possible to describe the annealing mechanism on a microscopic scale in terms of reaction-diffusion processes. The measured dependences of the boron diffusion coefficient of the enhanced diffusion on time, temperature and implantation energy are satisfactorily explained. (author).

1991-01-01

327

On the theory of transient enhanced diffusion in boron-implanted silicon  

International Nuclear Information System (INIS)

Transient enhanced diffusion in boron-implanted silicon is interpreted as being due to the fact that during rapid thermal annealing a relaxation process takes place, associated with quasi-chemical reactions including defects. A simple analytical model makes it possible to describe the annealing mechanism on a microscopic scale in terms of reaction-diffusion processes. The measured dependences of the boron diffusion coefficient of the enhanced diffusion on time, temperature and implantation energy are satisfactorily explained. (author).

328

Heat exchange enhancement structure  

Energy Technology Data Exchange (ETDEWEB)

A passive heat exchange enhancement structure which operates by free convection includes a flat mounting portion having a plurality of integral fins bent outwardly from one side edge thereof. The mounting portion is securable around a stovepipe, to a flat surface or the like for transferring heat from the pipe through the fins to the surrounding air by rotation-enhanced free convection.

1980-12-02

329

Boron-enhanced-diffusion of boron: The limiting factor for ultra-shallow junctions  

Energy Technology Data Exchange (ETDEWEB)

Reducing implant energy is an effective way to eliminate transient enhanced diffusion (TED) due to excess interstitials from the implant. It is shown that TED from a fixed Si dose implanted at energies from 0.5 to 20 keV into boron doping-superlattices decreases linearly with decreasing Si ion range, virtually disappearing at sub-keV energies. However, for sub-keV B implants diffusion remains enhanced and x{sub j} is limited to {ge} 100 nm at 1,050 C. The authors term this enhancement, which arises in the presence of B atomic concentrations at the surface of {approx} 6%, Boron-Enhanced-Diffusion (BED).

1997-12-01

330

Experimental and clinical studies on the usefulness and assessment of the angiographic images processed by a digital radiography system (FCR: Fuji Computed Tomography)  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study was to assess experimentally and clinically the usefulness of Fuji Computed Radiography (FCR) in angiographic examinations. FCR had a spatial resolution with much lower X-ray exposure doses, although the resolution of FCR was generally inferior to conventional films. When a contrast medium of 1% iodine concentration was used, FCR pinpointed a mass 1.5 mm in diameter; and conventional film could detect a mass 2.2 mm in diameter. The contrast of iodine in FCR examinations was stable. A high sensitivity of imaging plate allowed a wide range of visualization. In 148 selective angiographic examinatinons for 138 patients, FCR-subtraction images were superior to conventional film angiography for contrast resolution; it had a high sensitivity in detecting areas, such as the mediastimun and left lobe of the liver, and tumor stains in capillary phase. The capability of FCR arteriogram was as good as film ...

1989-06-01

331

Experimental and clinical studies on the usefulness and assessment of the angiographic images processed by a digital radiography system (FCR: Fuji Computed Tomography)  

International Nuclear Information System (INIS)

The purpose of this study was to assess experimentally and clinically the usefulness of Fuji Computed Radiography (FCR) in angiographic examinations. FCR had a spatial resolution with much lower X-ray exposure doses, although the resolution of FCR was generally inferior to conventional films. When a contrast medium of 1% iodine concentration was used, FCR pinpointed a mass 1.5 mm in diameter; and conventional film could detect a mass 2.2 mm in diameter. The contrast of iodine in FCR examinations was stable. A high sensitivity of imaging plate allowed a wide range of visualization. In 148 selective angiographic examinatinons for 138 patients, FCR-subtraction images were superior to conventional film angiography for contrast resolution; it had a high sensitivity in detecting areas, such as the mediastimun and left lobe of the liver, and tumor stains in capillary phase. The capability of FCR arteriogram was as good as film ...

1989-01-01

332

A simplified method of opacifying and mixing acrylic cement for percutaneous vertebroplasty: a clinical and in vitro study.  

Science.gov (United States)

The objective of this study was to simplify the opacifying mixing process of the bone cement and contrast used for percutaneous vertebroplasty (PVP). We performed a biomechanical study of polymethyl methacrylate (PMMA) (Corinplast 3) using three different mixtures of PMMA, monomer, and contrast: group I, 2:1; group II, 3:2; group III, 3:2:1 ratio of powder/monomer/iodinated contrast (Omnipaque). In vitro biomechanical testing of ultimate compressive strength was carried out in all samples. Following the conclusion of a proper bone cement mixture regimen drawn from the in vitro study, PVP was performed in 125 patients: 58 with cancer, 12 with hemangioma, and 54 with osteoporotic fracture. The ultimate compressive strength in group III was decreased by 38% compared to groups II and I. Proper fluoroscopic visualization was achieved in all PVP procedures using this mixture. There were no major complications associated with ...

333

A Simplified Method of Opacifying and Mixing Acrylic Cement for Percutaneous Vertebroplasty: A Clinical and In Vitro Study  

Science.gov (United States)

The objective of this study was to simplify the opacifying mixing process of the bone cement and contrast used for percutaneous vertebroplasty (PVP). We performed a biomechanical study of polymethyl methacrylate (PMMA) (Corinplast{sup TM} 3) using three different mixtures of PMMA, monomer, and contrast: group I, 2:1; group II, 3:2; group III, 3:2:1 ratio of powder/monomer/iodinated contrast (Omnipaque). In vitro biomechanical testing of ultimate compressive strength was carried out in all samples. Following the conclusion of a proper bone cement mixture regimen drawn from the in vitro study, PVP was performed in 125 patients: 58 with cancer, 12 with hemangioma, and 54 with osteoporotic fracture. The ultimate compressive strength in group III was decreased by 38% compared to groups II and I. Proper fluoroscopic visualization was achieved in all PVP procedures using this mixture. There were no major complications associated ...

2005-06-15

334

Real-time neutron coded aperture imaging: A technique for nondestructive three-dimensional imaging  

Energy Technology Data Exchange (ETDEWEB)

Neutron Coded Aperture Imaging is a nondestructive imaging technique that utilizes neutrons scattered from an object through specially designed apertures. Coded Aperture Imaging is an alternative technique to Computed Tomography for three-dimensional imaging. Coded Aperture Imaging has the advantage that all of the three-dimensional information is contained in a single image, whereas Computed Tomography requires several images or projections. This technique has been implemented by other using photographic film as an image recording medium and optical reconstruction or decoding of the images. In this work, the possibility of using a real-time neutron video camera to record the images, followed by digital decoding methodology has been investigated. Because only a small fraction of the neutrons incident on the object are scattered to the neutron camera, a new neutron beamport facility, with a larger neutron flux (7.3 x 10[sup 7] n/cm[sup 2]/s) than the previous facility was constructed. A ...

1992-01-01

335

Modification of ion-exchange resin composition for the removal of Gd of higher (15 ppm) concentration from moderator system of 540 MWe PHWRs  

International Nuclear Information System (INIS)

Addition of Gadolinium Nitrate as chemical shim to moderator heavy water of 540 MWe PHWR, at 15 mg/kg level (at a pH of 5.0) is practiced for reactor shutdown purposes. Presently a strong acid cation exchanger column is used for this purpose. During this operation, the moderator pH of 3.8, with the IX column outlet pH of ?3.5-3.6 was observed against the technical specification demand that when Gd is present, the pH of moderator must be in the range of 5.0-5.5. In order to achieve an iso-pH regime during Gd removal, studies were conducted using a mixed bed of strong acid cation resin plus a weak base anion resin (loaded in the volume ratio of 1 : 6), backed up in the same column (bottom most layer) by a 5 % nitric acid loaded weak base resin and topped by a strong acid cation resin (uppermost layer) simulating system flow velocity and percentage loading of resin. Using such a column it is demonstrated that Gd removal could be achieved simultaneously maintaining the ...

2006-11-13

336

K/sub. beta. //K/sub. cap alpha. / transition probability ratios from the measurement of fluorescent X-ray intensities of some lanthanide compounds  

Energy Technology Data Exchange (ETDEWEB)

The effect that different chemical and physical atomic environments can have on the relative intensities of radiative electron transitions from the filling of K shell vacancies was investigated. The method used involved the detection of photoionization induced X-ray fluorescence. An experimental system based on a hyper pure germanium detector (HPGE) was used to measure the relative K-L and K-M X-ray yields from the photofluorescence of a series of lanthanide elements and compounds. A background subtraction and peak integration strategy was employed which accounted for scattering in the samples and scattering of the flux from the radioisotope photoionization sources. Analysis of the data resulted in a tabulation of relative K/sub ..beta..//K/sub ..cap alpha../ X-ray intensity ratios. The measured relative K/sub ..beta..//K/sub ..cap alpha../ X-ray intensity ratios were compared to the calculated values predicted by the theoretical development of Scofield and the average of previous ...

1987-01-01

337

K/sub #beta#//K/sub #alpha#/ transition probability ratios from the measurement of fluorescent X-ray intensities of some lanthanide compounds  

International Nuclear Information System (INIS)

The effect that different chemical and physical atomic environments can have on the relative intensities of radiative electron transitions from the filling of K shell vacancies was investigated. The method used involved the detection of photoionization induced X-ray fluorescence. An experimental system based on a hyper pure germanium detector (HPGE) was used to measure the relative K-L and K-M X-ray yields from the photofluorescence of a series of lanthanide elements and compounds. A background subtraction and peak integration strategy was employed which accounted for scattering in the samples and scattering of the flux from the radioisotope photoionization sources. Analysis of the data resulted in a tabulation of relative K/sub #beta#//K/sub #alpha#/ X-ray intensity ratios. The measured relative K/sub #beta#//K/sub #alpha#/ X-ray intensity ratios were compared to the calculated values predicted by the theoretical development of Scofield and the average of previous experimental values ...

1987-01-01

338

Gadolinium removal from the moderator system of TAPP - 3 using the three layer bed  

International Nuclear Information System (INIS)

Nitric acid leaching from the weak base anion (WBA) exchanger had been evaluated and based on this a 5% mixture of nitric acid loaded weak base anion exchanger with fresh weak base anion exchanger (NLWBA) at the bottom of the ion exchange column has been devised to maintain an outlet pH in the range of 5.0 to 5.5 during Gd removal from the moderator system of TAPP - 3 and 4. A three layered bed had been constituted wherein strong acid cation (SAC) exchanger is placed as the top layer while a mixed bed of SAC and WBA or pure WBA is used as the middle layer and the 5% NLWBA was used as the bottom most layer. This bed configuration would result in an iso-pH regime in the moderator system during the Gd removal along with quantitative removal of Gd. Two three-layer bed columns were prepared at TAPS - 3 and 4 in July 07. The resin was loaded in batches and after preparing the column, the column was deuterated with heavy water (> 99.75 % w/w) at a steady flow rate of 280 ml/min. After ...

2008-12-01

339

Emesis ED50 of neutron irradiation and prophylactic effectiveness. Final report, 1 January 1979-31 December 1984  

Energy Technology Data Exchange (ETDEWEB)

Two neutron emesis experiments were conducted at the Armed Forces Radiobiology Research Institute (AFRRI). In both experiments (described as Phase I and Phase II) the radiation dose required to cause emesis in 50% of subjects (ED50) was determined for both neutron reactor and gamma reactor source radiation. Emesis onset, offset and duration times post-exposure are reported. Neutrons were maximized from the reactor by passing the beam through a 15.25 cm (6 in.) thick lead wall to filter out gamma photons. Gamma rays were maximized by thermalizing neutrons in 30.5 cm (12 in.) of water, then absorbing the thermal neutrons in a gadolinium-cadmium shield. In Phase I, 28 dogs were exposed to radiation: 12 were exposed to gamma photons at the rate of 0.69 Gy/min and 16 were exposed to neutrons at 1.2 Gy/min. In Phase II, 58 dogs in 3 groups were exposed to radiation: 19 were exposed in the gamma group at 0.75 Gy/min, 20 were exposed in the undrugged neutron group at 1.62 ...

1985-08-01

340

Development of methodics for the characterization of the composition of the ion-collision-induced secondary-particle flux by comparison of the yield contributions of photoinduced ion formation processes; Entwicklung einer Methodik zur Charakterisierung der Zusammensetzung des ionenbeschussinduzierten Sekundaerteilchenflusses durch Vergleich der Ausbeuteanteile photoinduzierter Ionenbildungsprozesse  

Energy Technology Data Exchange (ETDEWEB)

The aim of this work was to develop a method to distinguish between different ion formation processes and to determine the influence of these processes on the total number of detected monatomic ions of a certain element. A vector/matrix-formalism was developed, which describes the physical processes of sputtering, ion formation, mass separation and detection in laser-SNMS. In the framework of the method developed, based on this theoretic formalism, changes in the secondary flux contribution of the respective element were observed by comparing the detected monatomic ion yield obtained in specifically aligned (SIMS and) laser-SNMS experiments. The yields resulting from these experiments were used to calculate characteristic numbers to compare the flux composition from different surfaces. The potential of the method was demonstrated for the elements boron, iron and gadolinium by investigating the changes in the flux composition of secondary particles sputtered from ...

2008-10-13

341

Comparative study of the crystal field effects in rare earth oxynitrates  

Energy Technology Data Exchange (ETDEWEB)

The photoluminescence spectra of the lanthanum and gadolinium oxynitrates doped with Eu[sup 3+], REONO[sub 3]:Eu[sup 3+] (RE=La and Gd) were measured at 77 and 300 K. The [sup 7]F[sub J] (J=0-5) energy level schemes for the 4f [sup 6] electron configuration were simulated by a C[sub 2v] phenomenological crystal field (CF). The nine non-zero CF parameters for the C[sub 2v] site symmetry reproduce the experimental energy level schemes with rms deviations of 7 and 5 cm[sup -1] for the LaONO[sub 3] and GdONO[sub 3] hosts, respectively. The CF effect is stronger in the lanthanum host although otherwise the CF parameters for the two oxynitrate hosts differ only slightly. The B[sup k][sub 2] (k=2, 4 and 6) values are low indicating only a slight deviation from a higher C[sub 4v] symmetry. The B[sup 2][sub 0], B[sup 4][sub 0] and B[sup 4][sub 4] parameters assume high values which are similar to those obtained previously for the other RE oxy compounds, i.e. oxyhalides, ...

1994-06-01

342

Commissioning and operation of new liquid poison injection based shut down system in TAPP-3 and 4  

International Nuclear Information System (INIS)

Shut Down System - 2 (SDS - 2) of TAPP-3 and 4 works on the principle of rapid injection of gadolinium nitrate poison solution into bulk moderator in calandria using high pressure helium to shut down the reactor. This is a new system, in the context of Indian PHWRs, designed, engineered, commissioned and being operated in TAPP-3 and 4. The system design incorporates passive features such as floating polyethylene ball with ball-ball seat arrangement and locked open isolation ball valves with key interlock arrangement. This arrangement eliminates active valves downstream of poison tanks during SDS - 2 actuation. A series parallel arrangement of fast acting pilot controlled air operated valves, which keep the high pressure helium isolated from poison tanks in poised state, are the only active components. During commissioning and initial period of operation of TAPP-4, problems were encountered and were resolved by suitable modifications and the same were incorporated ...

2006-11-13

343

A comparison of x-ray detectors for mouse CT imaging  

International Nuclear Information System (INIS)

There is significant interest in using computed tomography (CT) for in vivo imaging applications in mouse models of disease. Most commercially available mouse x-ray CT scanners utilize a charge-coupled device (CCD) detector coupled via fibre optic taper to a phosphor screen. However, there has been little research to determine if this is the optimum detector for the specific task of in vivo mouse imaging. To investigate this issue, we have evaluated four detectors, including an amorphous selenium (a-Se) detector, an amorphous silicon (a-Si) detector with a gadolinium oxysulphide (GOS) screen, a CCD with a 3:1 fibre taper and a GOS screen, and a CCD with a 2:1 fibre taper and both GOS and thallium-doped caesium iodide (CsI:Tl) screens. The detectors were evaluated by measuring the modulation transfer function (MTF), noise power spectrum (NPS), detective quantum efficiency (DQE), stability over multiple exposures, and noise in reconstructed CT images. The a-Se ...

2004-12-07

344

MRT of the abdomen in combination with enteroclysis in Crohn disease with oral and intravenous Gd-DTPA  

International Nuclear Information System (INIS)

60 patients between 17 and 72 years of age were investigated. First, an enteroclysis was performed in typical manner. The applicated methylcellulosis was blended with positive oral MR contrast media (Magnevist oral, Schering). After enteroclysis, MRI of the abdomen was performed using T1- and T2-weighted breathhold sequences (Flash 2D pre- and postcontrast and TSE) in axial and coronal planes. The length of the affected bowel and the stenosis seen with enteroclysis correlated well with the visible thickening of the small bowel wall and the stenosis seen in MRI. Using MRI, additional findings could be obtained in 28 patients, such as fistulas, abscesses or a hydronephrosis, or a better assessment of the stenosis was possible with MRI, because of the avoidance of overshadowing of the affected bowel loop with MRI. A brilliant MR-tomographic imaging of the small bowel is possible under the condition, that the small bowel contrast is optimal. The ...

345

Lasing efficiency and tuning range of a dynamic distributed-feedback laser  

Energy Technology Data Exchange (ETDEWEB)

The effects of the contrast of the pump field interference pattern, that is, the effectiveness of the dynamic amplitude-phase grid, and various optical arrangements on the lasing efficiency and tuning range of a dynamic distributed-feedback dye laser are investigated. It is shown that the proper choice of prism apex angle, prism material and dye solvent in a laser in the range 400-1000 microns pumped by two beams of different intensity directed through the congruent sides of an isosceles prism in contact with the active medium solution on its third side can lead to optical losses of less than 2% from the boundaries of the prism. Measurements of polymethine dye laser efficiency and tuning range as a function of the relative intensity of the two ruby-laser pump beams reveals that as the contrast of the pump beam interference pattern decreases, the tuning range remains practically constant and the efficiency increases in the nonlinear (saturation) ...

1980-08-01

346

Evaluation of selective alveolo-bronchography with Fuji computed radiography and x-ray CT  

International Nuclear Information System (INIS)

Selective alveolo-bronchography (SAB) has been routinely used to evaluate anatomical changes in the bronchiole and its distal air spaces. A narrowing of the bronchiole and abnormal pooling of contrast medium in the destroyed air space are the prime findings. Since the object of radiography is extremely thin, direct magnification radiography is mandatory to obtain radiologic details. However, the problem with this technique is that radiographic quality varies depending upon the size of the patient and the concentration of contrast medium to be introduced in the lung. This study had two goals. One was to improve the image quality of SAB by Fuji Computed Radiography (FCR). FCR provides radiographs with a good contrast and stable density throughout a wide range of exposure factors which occur in the use of SAB. The other goal was to separately evaluate morphological abnormalities in the outer and inner zones of the lung using ...

1986-01-01

347

Evaluation of computer-aided detection of lesions in mammograms obtained with a digital phase-contrast mammography system  

Energy Technology Data Exchange (ETDEWEB)

A computer-aided detection (CAD) system was evaluated for its ability to detect microcalcifications and masses on images obtained with a digital phase-contrast mammography (PCM) system, a system characterised by the sharp images provided by phase contrast and by the high resolution of 25-{mu}m-pixel mammograms. Fifty abnormal and 50 normal mammograms were collected from about 3,500 mammograms and printed on film for reading on a light box. Seven qualified radiologists participated in an observer study based on receiver operating characteristic (ROC) analysis. The average of the areas under ROC curve (AUC) values for the ROC analysis with and without CAD were 0.927 and 0.897 respectively (P = 0.015). The AUC values improved from 0.840 to 0.888 for microcalcifications (P = 0.034) and from 0.947 to 0.962 for masses (P = 0.025) respectively. The application of CAD to the PCM system is a promising approach for the detection of breast cancer in its ...

2009-12-15

348

A new application of MRT of the lung using ultra-shot turbo spin echo sequences (UTSE)  

International Nuclear Information System (INIS)

T_2 weighted ultra-short turbo spin echo sequences were used in five individuals with variations in echo times, delayed triggering and echo intervals. To reduce movement artifacts all examinations were carried out with ECG and respiratory triggering. The sequences giving optimal image quality were then employed in 19 patients having various pulmonary abnormalities. Image resolutions, artifacts, image contrasts and diagnostic value were then judged by two observers and compared with CT. In the first study, a diastole-triggered UTSE sequence with the shortest echo proved optimal (T_E=90 ms, T_R=2-4 s, echo=9 ms, turbo factor=19). In the patient series studied, MRT was inferior to CT with regard to resolution and number of artifacts, but better in respect of contrast and diagnostic value. Using UTSE of the lung, MRT can produce images of good quality. Compared with CT, contrast is better with MRT, offering diagnostic ...

349

StoRHm: a protocol adapter for mapping SOAP based Web Services to RESTful HTTP format  

British Library Electronic Table of Contents (United Kingdom)

A protocol adapter ideally suited to enable enterprises to gradually transition from SOAP Web Services to RESTful HTTP Web Services without impacting existing clients is presented in this paper. The inherent advantage of such a transition is the visibility of RESTful HTTP messages to Web intermediaries such as caches. In contrast, SOAP messages are opaque, which disables Web intermediaries. While both approaches can use HyperText Transfer Protocol (HTTP) for message transfer, the paradigms contrast sharply. SOAP uses an interface specific approach whereas RESTful HTTP uses a Uniform Interface approach. SOAP marks up its payload with eXtensible Markup Language (XML) whereas in certain situations RESTful HTTP requires no XML. We present the disadvantages of the SOAP approach and outline how ...

2011-01-01

350

Role of MRI in the diagnostic evaluation of parotid diseases  

International Nuclear Information System (INIS)

MRI findings in 13 patients with monolateral parotid tumor were compared with US, sialographic and CT findings. MRI did not allow an accurate diagnosis in 2 patients with diffuse chronic parotitis. MRI was superior to CT in 1 case in defining the intraglandular site of the lesion, and in 2 patients in showing the extraglandular involvement. MRI proved to be superior to CT thanks to its contrast resolution and to multiplanar imaging. MRI high contrast resolution made it possible to demonstrate neoplastic lesions of 4 mm in diameter. The lesion has low signal intensity on T1-weighted images and high signal intensity on T2-weighted. Parotid tumors cannot be characterized by signal intensity alone: only morphology allows to discriminate between benign and malignant lesions. To conclude, US is a screening method, while MRI is helpful in detecting multifocal lesions and in evaluating the tumor extent.

1988-01-01

351

Response of ecosystem carbon exchange to warming and nitrogen addition during two hydrologically contrasting growing seasons in a temperate steppe  

British Library Electronic Table of Contents (United Kingdom)

Abstract A large remaining source of uncertainty in global model predictions of future climate is how ecosystem carbon (C) cycle feedbacks to climate change. We conducted a field manipulative experiment of warming and nitrogen (N) addition in a temperate steppe in northern China during two contrasting hydrological growing seasons in 2006 [wet with total precipitation 11.2% above the long-term mean (348 mm)] and 2007 (dry with total precipitation 46.7% below the long-term mean). Irrespective of strong intra- and interannual variations in ecosystem C fluxes, responses of ecosystem C fluxes to warming and N addition did not change between the two growing seasons, suggesting independence of warming and N responses of net ecosystem C exchange (NEE) upon hydrological variations in the temperate ...

2009-01-01

352

Raney-platinum film electrodes for potentially implantable glucose fuel cells. Part 1: Nickel-free glucose oxidation anodes  

British Library Electronic Table of Contents (United Kingdom)

We present a novel fabrication route yielding Raney-platinum film electrodes intended as glucose oxidation anodes for potentially implantable fuel cells. Fabrication roots on thermal alloying of an extractable metal with bulk platinum at 200^oC for 48h. In contrast to earlier works using carcinogenic nickel, we employ zinc as potentially biocompatible alloying partner. Microstructure analysis indicates that after removal of extractable zinc the porous Raney-platinum film (roughness factor ~2700) consists predominantly of the Pt3Zn phase. Release of zinc during electrode operation can be expected to have no significant effect on physiological normal levels in blood and serum, which promises good biocompatibility. In contrast to previous anodes based on hydrogel-bound catalyst particles the ...

2010-01-01

353

PET/MRI hybrid imaging: devices and initial results  

British Library Electronic Table of Contents (United Kingdom)

The combination of functional and morphological imaging technologies such as positron emission tomography (PET) and X-ray computed tomography (CT) has shown its value in the clinical and preclinical field. However, CT provides only very limited soft-tissue contrast and exposes the examined patient or laboratory animal to a high X-ray radiation dose. In comparison to CT, magnetic resonance tomography (MRI) provides excellent soft-tissue contrast and allows for nuclear magnetic resonance spectroscopy (NMRS) or functional MRI (fMRI). Thus, the combination of PET and MRI has been pursued for several years. First approaches have succeeded using conventional photo multiplier tube (PMT) technology together with light fibers to transfer scintillation light away from the high magnetic field. Latest...

2008-01-01

354

Opportunistic esophagitis in AIDS: Radiographic diagnosis  

International Nuclear Information System (INIS)

Between 1983 and 1986, 35 of 90 patients with acquired immunodeficiency syndrome (AIDS) had double-contrast esophagograms to rule out opportunistic esophagitis. The radiographs were reviewed without knowledge of the clinical or endoscopic findings. Candida esophagitis was diagnosed radiographically in 17 patients who had varying degrees of plaque formation and viral esophagitis in three who had discrete ulcers without plaques. All three patients with viral esophagitis (herpes in 2 and cytomegalo virus in one) and 15 of 17 with Candida esophagitis had endoscopic and/or clinical corroboration of the radiographic diagnosis. Thus, the authors' experience suggests that fungal and viral esophagitis can often be differentiated on double-contrast esophagography, so that appropriate antifungal or antiviral therapy can be instituted without need for endoscopic intervention.

355

Fetal magnetic resonance imaging of the brain: technical considerations and normal brain development  

International Nuclear Information System (INIS)

Fetal MRI examines non-invasively the unborn fetus. Ultrafast MRI sequences effectively suppress fetal motion. Multiple case reports and studies have shown that fetal MRI is particularly helpful in the evaluation of the central nervous system. The high contrast-to-noise ratio, the high spatial resolution, the multiplanar capabilities, the large field of view and the simultaneous visualisation of fetal and maternal structures have proven to be advantageous. Fetal MRI is particularly helpful in the evaluation of the normal and pathological development of the brain. Despite the fact that no side effects have been reported or are to be expected, the use of MRI during pregnancy is still limited to the second and third trimester of pregnancy. Magnetic resonance imaging contrast media are not to be used as it passes the placenta. Ultrasound remains the primary screening modality for fetal pathology; fetal MRI can serve as an adjunct or second-line ...

2002-08-01

356

Feasibility study of the iterative x-ray phase retrieval algorithm  

International Nuclear Information System (INIS)

An iterative phase retrieval algorithm was previously investigated for in-line x-ray phase imaging. Through detailed theoretical analysis and computer simulations, we now discuss the limitations, robustness, and efficiency of the algorithm. The iterative algorithm was proved robust against imaging noise but sensitive to the variations of several system parameters. It is also efficient in terms of calculation time. It was shown that the algorithm can be applied to phase retrieval based on one phase-contrast image and one attenuation image, or two phase-contrast images; in both cases, the two images can be obtained either by one detector in two exposures, or by two detectors in only one exposure as in the dual-detector scheme.

2009-01-01

357

Digital processing to improve image quality in real-time neutron radiography  

Energy Technology Data Exchange (ETDEWEB)

Real-time neutron radiography (NTV) has been used for practical applications at the Kyoto University Reactor (KUR). At present, however, the direct image from the TV system is still poor in resolution and low in contrast. In this paper several image improvements are demonstrated, such as a frame summing technique, which are effective in increasing image quality in neutron radiography. Image integration before the A/D converter has a beneficial effect on image quality and the high quality image reveals details invisible in direct images, such as: small holes by a reversed image, defects in a neutron converter screen through a high quality image, a moving object in a contoured image, a slight difference between two low-contrast images by a subtraction technique, and so on. For the real-time application a contouring operation and an averaging approach can also be utilized effectively.

1985-01-01

358

Digital processing to improve image quality in real-time neutron radiography  

International Nuclear Information System (INIS)

Real-time neutron radiography (NTV) has been used for practical applications at the Kyoto University Reactor (KUR). At present, however, the direct image from the TV system is still poor in resolution and low in contrast. In this paper several image improvements are demonstrated, such as a frame summing technique, which are effective in increasing image quality in neutron radiography. Image integration before the A/D converter has a beneficial effect on image quality and the high quality image reveals details invisible in direct images, such as: small holes by a reversed image, defects in a neutron converter screen through a high quality image, a moving object in a contoured image, a slight difference between two low-contrast images by a subtraction technique, and so on. For the real-time application a contouring operation and an averaging approach can also be utilized effectively. (orig.).

1985-01-01

359

Angiography of the head using Fuji computed radiography (FCR) system  

International Nuclear Information System (INIS)

Forty-seven subtraction images of FCR were compared with subtraction images of conventional angiography of the head. Quality of the FCR images were equal or superior to that of conventional angiography. Antero-posterior projection of external carotid arteriography by FCR was most useful because of its wide dynamic range. As contrast resolution of FCR is superior to that of conventional angiography, only half diluted contrast media was needed. As for spacial resolution, FCR is slightly inferior to conventional angiography. However, most vessels which are clinically important were adequately demonstrated. A weak point of FCR which should be improved is relatively long time to process the images after radiation exposure. (author).

1985-01-01

360

The angiogram sign in pulmonary atelectasis studied with helical Computed Tomography. Incidence and value; Il segno dell'angiogramma nelle atelettasie polmonari studiate con Tomografia Computerizzata spirale. Incidenza e validita' semeiologica  

Energy Technology Data Exchange (ETDEWEB)

In this issue it has been investigated the yield of Helical CT in the study of lung vessels, the incidence of the angiogram sign and its actual value. July 1997 to December 1998, were studied 30 cases of pulmonary collapse of different origin. It was found 15 cases of passive collapse (10 from pleural effusion, 2 from diaphragmatic compression, 2 from traumatic pneumothorax, and 1 from isthmic aortic aneurysm), 12 cases of obstructive collapse (9 from bronchogenic carcinoma, 1 from mucoid obstruction, 1 from ilar lymphadenopathy, and 1 from mediastinal cancer), 2 cases of adhesive collapse and 1 case of round atelectasis. All the examinations were performed with the Helical technique during nonionic iodinated contrast agent injection (bolus, 300-350 mg/mL); it was used an automatic injector set at 2-3 mL/s. It was studied the images for the angiogram sign, that is hyperdense bands, usually longer than 2 cm, through the collapsed lung, which correspond to normal ...

1999-12-01

361

Gastric stromal tumors. CT findings; Tumori stromali gastrici. Aspetti con Tomografia Computerizzata  

Energy Technology Data Exchange (ETDEWEB)

Gastric stromal tumors are an ill-defined group of lesions arising from muscle wall cells and characterized by extremely variable biological patterns. Thanks to modern immunohistochemical and ultrastructural techniques, four main classes of these lesions have been identified, namely: (1) tumors with differentiation toward smooth muscle cells; (2) tumors with differentiation toward neural elements; (3) tumors with differentiation toward neural elements; (3) tumors with dual differentiation toward either cell type. It was investigated the yield of CT in diagnosing and characterizing gastric stromal tumors. It was retrospectively reviewed the CT findings of 38 patients (15 men and 23 women; mean age 51 years) with pathologically proven gastric stromal tumors, namely 31 of myoid origin, 4 of neural origin, 2 with both muscle and neural differentiation, 1 lacking differentiation with either cell type. The myoid tumors involved gastric fundus in 9/13 and 5/7 benign lesions and lesions with ...

2000-02-01

362

Helical CT of traumatic injuries of the thoracic aorta; Applicazioni della Tomografia Computerizzata spirale nello studio delle lesioni traumatiche dell'aorta toracica  

Energy Technology Data Exchange (ETDEWEB)

Acute thoracic aortic injuries account for up to 10-20% of fatalities in high-speed deceleration road accidents and have an estimated immediate fatality rate of 80-90%. Untreated survivors to acute trauma (10-20%) have a dismal prognosis: 30% of them die within 6 hours, 40-50% die within 24 hours, and 90% within 4 months. It was investigated the diagnostic accuracy of Helical Computed Tomography (Helical CT) in acute traumatic injuries of the thoracic aorta, and the role of this technique in the diagnostic management of trauma patients with a strong suspicion of aortic rupture. It was compared retrospectively the chest Helical CT findings of 256 trauma patients examined June 1995 through August 1999. Chest Helical CT examinations were performed according to trauma score, to associated traumatic lesions and to plain chest radiographic findings. All the examinations were performed with no intravenous contrast agent administration and the pitch 2 technique. After a ...

2000-09-01

363

Ultraviolet upconversion luminescence enhancement in Yb3+/Er3+-codoped Y2O3 nanocrystals induced by tridoping with Li+ ions  

International Nuclear Information System (INIS)

Ultraviolet (UV) upconversion (UC) luminescence in Yb3+/Er3+-codoped yttrium oxide (Y2O3) nanocrystals can be enhanced by orders of magnitude via tridoping further with Li+ ions under diode laser excitation of 970 nm. Sensitized three-photon UC radiations at 390 and 409 nm, corresponding to the 4G11/2?4I15/2 and 4H9/2?4I15/2 of Er3+ ions, respectively, present an enhancement time of about 33 times, which is larger than the 24 times enhancement for the UC green radiation. The UV UC radiation at 320 nm that corresponds to the 2P3/2?4I15/2 of Er3+ ions has also been greatly enhanced. Theoretical calculations interpret that all the observed enhancement times of UV UC radiations arise from the prolonged lifetimes of their intermediate states.

2009-03-01

364

Heat transfer augmentation in a heat exchanger tube using a baffle  

International Nuclear Information System (INIS)

Heat transfer enhancement in a heat exchanger tube by installing a baffle is reported. The effect of baffle size and orientation on the heat transfer enhancement was studied in detail. Three different baffle arrangements were considered. The results show that for the vertical baffle, an increase in the baffle height causes a substantial increase in the Nusselt number but the pressure loss is also very significant. For the inclined baffles, the results show that the Nusselt number enhancement is almost independent of the baffle inclination angle, with the maximum and average Nusselt number 120% and 70% higher than that for the case of no baffle, respectively. For a given baffle geometry, the Nusselt number enhancement is increased by more than a factor of two as the Reynolds number decreased from 20,000 to 5000. Simulations were conducted by introducing another baffle to enhance heat ...

2007-04-01

365

Experimental study of the characteristics of solidification of stearic acid in an annulus and its thermal conductivity enhancement  

Energy Technology Data Exchange (ETDEWEB)

The thermal and heat transfer characteristics of stearic acid during the solidification processes were investigated experimentally in a vertical annulus energy storage system. The temperature distribution and temperature variations with time at different radial positions during the freezing processes were obtained. The thermal characteristics of the stearic acid, including movement of the solid-liquid interface in the radial direction, and the effects of Reynolds number on the heat transfer parameters were studied. The heat flux was estimated by using a simple approximate model. A new copper fin was designed and fixed to the electrical heating rod to enhance the thermal conductivity of the stearic acid. The results show that the new fin can enhance both the conduction and the natural convection heat transfer of the PCM, and the enhancement factor during solidification is estimated to be as high as 250%. The effect of the ...

2005-04-01

366

Experimental study of the characteristics of solidification of stearic acid in an annulus and its thermal conductivity enhancement  

Energy Technology Data Exchange (ETDEWEB)

The thermal and heat transfer characteristics of stearic acid during the solidification processes were investigated experimentally in a vertical annulus energy storage system. The temperature distribution and temperature variations with time at different radial positions during the freezing processes were obtained. The thermal characteristics of the stearic acid, including movement of the solid-liquid interface in the radial direction, and the effects of Reynolds number on the heat transfer parameters were studied. The heat flux was estimated by using a simple approximate model. A new copper fin was designed and fixed to the electrical heating rod to enhance the thermal conductivity of the stearic acid. The results show that the new fin can enhance both the conduction and the natural convection heat transfer of the PCM, and the enhancement factor during solidification is estimated to be as high as 250%. The effect of the ...

2005-04-01

367

Enhanced sludge washing evaluation plan  

Energy Technology Data Exchange (ETDEWEB)

The Tank Waste Remediation System (TWRS) Program mission is to store, treat, and immobilize highly radioactive Hanford Site waste (current and future tank waste and the strontium/cesium capsules) in an environmentally sound, safe, and cost-effective manner. The scope of the TWRS Waste Pretreatment Program is to treat tank waste and separate that waste into HLW and LLW fractions and provide additional treatment as required to feed LLW and HLW immobilization facilities. Enhanced sludge washing was chosen as the baseline process for separating Hanford tank waste sludge. Section 1.0 briefly discusses the purpose of the evaluation plan and provides the background that led to the choice of enhanced sludge washing as the baseline process. Section 2.0 provides a brief summary of the evaluation plan details. Section 3.0 discusses, in some detail, the technical work planned to support the evaluation of enhanced sludge washing. ...

1994-09-01

368

Diffusion modeling of ion implanted boron in Si during RTA: Correlation of extended defect formation and annealing with the enhanced diffusion of boron. [Rapid Thermal Annealing  

Energy Technology Data Exchange (ETDEWEB)

Accurate modeling of the enhanced diffusion of boron during rapid thermal annealing has been accomplished by incorporating the effects of extended defect formation and annealing on enhanced diffusion into a multizone, semiempirical model. The multizone model divides the implant profile into three zones defining regions of different defects and diffusion enhancements. The model also contains the initial enhanced diffusion and the transient diffusion effects associated with the dissolution of defect clusters and the annealing of extended defects, respectively. The saturation time for transient-enhanced diffusion contains an exponential function of implant dose in order to model the increase in point defect generated with higher implant dose. As a result, the model accurately simulates the boron diffusion profile over a wide range of implant doses and also shows the immobile boron peak ...

1993-01-01

369

Annealing and diffusion characteristics of boron-through-oxide implanted silicon  

Energy Technology Data Exchange (ETDEWEB)

The author investigates the diffusion and damage-annealing characteristics as a result of boron implantation through a surface oxide into the silicon, a process that is commonly realized in the fabrication of p-n junctions. Defect structures were examined using plan-view and cross-section transmission-electron microscopies. It is shown that recoil-implanted oxygen plays a critical role in determining the above annealing characteristics. For instance, transient-enhanced diffusion of boron, as is widely observed for boron-implanted silicon, does not occur in the case of through-oxide implantation. The initial suppression of the defect-enhanced diffusion lasts for a limited period of time after which enhanced diffusion occurs again. The so-called incubated enhanced diffusion' is characterized as due to recoiled-oxygen precipitation-emitting point defect that enhances boron ...

1991-01-01

370

Annealing and diffusion characteristics of boron-through-oxide implanted silicon  

International Nuclear Information System (INIS)

The author investigates the diffusion and damage-annealing characteristics as a result of boron implantation through a surface oxide into the silicon, a process that is commonly realized in the fabrication of p-n junctions. Defect structures were examined using plan-view and cross-section transmission-electron microscopies. It is shown that recoil-implanted oxygen plays a critical role in determining the above annealing characteristics. For instance, transient-enhanced diffusion of boron, as is widely observed for boron-implanted silicon, does not occur in the case of through-oxide implantation. The initial suppression of the defect-enhanced diffusion lasts for a limited period of time after which enhanced diffusion occurs again. The so-called incubated enhanced diffusion' is characterized as due to recoiled-oxygen precipitation-emitting point defect that enhances boron motion. The ...

371

Ultrasonic enhancement of heat transfer on narrow surface  

Energy Technology Data Exchange (ETDEWEB)

Ultrasonic enhancement of heat transfer on a narrow surface was measured by changing the width of the surface from 8 to 0.1 mm. Ultrasonic power of 600 W with a frequency of 40 kHz was used. Heat transfer on the narrow surface without ultrasonic vibration was correlated by the experimental equation for a thin wire. The cavitation intensity was measured by the cavitation erosion loss of an aluminum foil of 15 [mu]m thickness. The effects of acoustic streaming and cavitation were separated by this measurement. Heat transfer by acoustic streaming was predicted through forced convection. Enhancement by cavitation was explained by the turbulence thermal conductivity of the microjets.

1994-06-01

372

Point defect supersaturation and enhanced diffusion in SPE regrown silicon  

Energy Technology Data Exchange (ETDEWEB)

Transient, greatly enhanced diffusion has been observed on annealing solid-phase-epitaxial (SPE) grown Si-Sb alloys. This is shown to be due to a high concentration of interstitials being trapped during SPE regrowth. The migration enthalpy, for diffusion of Sb by an interstitialcy mechanism was measured as 1.8 +/- 0.2 eV. The interstitials eventually condensed into loops, marking the end of the transient. In a SPE grown Si-Bi alloy a similar transient enhanced diffusion was observed, with an activation energy of 2.0 +/- 0.2 eV, but no loops formed. 8 figures, 7 references.

1984-01-01

373

Point defect supersaturation and enhanced diffusion in SPE regrown silicon  

International Nuclear Information System (INIS)

Transient, greatly enhanced diffusion has been observed on annealing solid-phase-epitaxial (SPE) grown Si-Sb alloys. This is shown to be due to a high concentration of interstitials being trapped during SPE regrowth. The migration enthalpy, for diffusion of Sb by an interstitialcy mechanism was measured as 1.8 +/- 0.2 eV. The interstitials eventually condensed into loops, marking the end of the transient. In a SPE grown Si-Bi alloy a similar transient enhanced diffusion was observed, with an activation energy of 2.0 +/- 0.2 eV, but no loops formed. 8 figures, 7 references.

374

Investigations for obtaining enhanced SHG element of KH_2PO_4 crystal  

International Nuclear Information System (INIS)

We report investigations of enhancement in material conversion efficiency of KDP for SHG applications. The limitation of conventional technique of growing KDP crystal was overcome in the present work by adopting a growth method to grow KDP directly in type-II phase matching direction. The conventional technique results in #approx#30% of the crystal volume usable for SHG applications whereas the present method has resulted in enhancing it to #approx#90%. The orientation of the element was confirmed by frequency conversion experiment using Nd:YAG laser. The UV-vis transmittance obtained was 92%. The interferometric results show that the crystals have excellent optical homogeneity.

2010-04-01

375

Film condensation of HCFC-22 on horizontal enhanced tubes  

Science.gov (United States)

Experiments were conducted to study the condensation heat transfer characteristics of horizontal enhanced tubes. In the current experiment, six different enhanced tubes, including 26, 40 fpi low fin tubes and four three-dimensional-fin tubes, were tested. The working fluid used in the experiment was HCFC-22. Data were presented in the form of overall heat transfer coefficient at three working pressures, namely 1.32, 1.47 and 1.62 Mpa. In addition, the condensing heat transfer coefficients for the test tubes were obtained from the Wilson plot technique.

1996-01-01

376

Enhancement of the absorption of CO{sub 2} in alkaline buffer solutions: Joint action of two enhancers  

Energy Technology Data Exchange (ETDEWEB)

The authors measured the absorption of CO{sub 2} in alkaline 0.5 M/0.5 M sodium carbonate/bicarbonate buffers containing either saccharose and sodium arsenite or saccharose and formaldehyde. Absorption enhancement increased upon increasing the concentration of either of the catalysts, but the joint action of the two was always less than the sum of their individual effects, the difference being a function of the acidities and concentrations of the catalysts and the pH of the carbonate/bicarbonate buffer solution

1999-05-01

377

Enhanced LMR core cooling utilizing passive vortex devices  

International Nuclear Information System (INIS)

This paper reports several design options for improved passive circulation flow investigated for use in small, modular liquid metal cooled reactors (LMRs). The purpose is to enhance the transition to natural convection cooling following loss of forced circulation flow, reducing thermal transients experienced by the fuel and possibly eliminating the need for emergency pony-motor flow. Design details to minimize pressure drops may also enhance maximum equilibrium power levels possible under natural circulation only.

1988-05-01

378

Enhanced LMR [liquid metal reactors] core cooling utilizing passive vortex devices  

International Nuclear Information System (INIS)

Several design options for improved passive circulation flow have been investigated for use in small, modular liquid metal cooled reactors (LMRs). The purpose is to enhance the transition to natural convection cooling following loss of forced circulation flow, reducing thermal transients experienced by the fuel and possibly eliminating the need for emergency pony-motor flow. Design details to minimize pressure drops may also enhance maximum equilibrium power levels possible under natural circulation only.

1988-05-01

379

US Army Self-Development: Enhancer or Barrier to Leader ...  

Science.gov (United States)

... This must be taken a step further in counseling and other feedback and ... Record System Power Point Presentation ,www.armyppt.com/ncoer/6.htm ...

2003-05-01

380

Transport energy efficiency  

International Nuclear Information System (INIS)

Enhancing transport sustainability is the password of national, European, and international policies. The development of innovative solutions is ranging from bio fuels to transport analysis models, materials, traction technologies, mobility management, freight villages.

381

Transhumanism, medical technology and slippery slopes  

UK PubMed Central (United Kingdom)

In this article, transhumanism is considered to be a quasi‐medical ideology that seeks to promote a variety of therapeutic and human‐enhancing aims. Moderate conceptions are distinguished...Full Text Available

2006-09-01

382

Thermodynamics of Multivalent Interactions: Influence of the Linker  

UK PubMed Central (United Kingdom)

This paper describes a thermodynamic analysis of multivalent interactions, with the goal of clarifying the influence of the linker on the enhancement in avidity due to multivalency. The use...Full Text Available

2010-06-01

383

The Development of Enhanced Heat Transfer Condenser ...  

Science.gov (United States)

Page 1. - AERE-' R-7310 THIS DOCUMENT 15 INTENDED FOR PUBLICATION IN THE OPEN LITERATURE. ... Y Page 3. AERE R I 7318 ...

1973-07-01

384

The Changing Face of Urology in 2005  

UK PubMed Central (United Kingdom)

The practice of urology is changing, not only from a medical and technological standpoint, but also from a business standpoint. New and improved computer technology and enhanced databases have allowed...Full Text Available

2004-01-01

386

Summer Opportunities-Teacher Enhancement (NSF 96-89)  

Science.gov (United States)

... exercises and biotechnology labs and didactic material. It includes sessions on computer and media ... computers, and learn how IPT activities and materials can help meet their curriculum objects ...

388

Reducing the Cancer Burden of Lifestyle Factors: Opportunities and Challenges of the Internet  

UK PubMed Central (United Kingdom)

This paper focuses on the Internet as a tool for enhancing behavior and lifestyle changes to reduce the burden of cancer at a population level. The premise of this paper is that the Internet...Full Text Available

389

Prediction of transient-enhanced diffusion during rapid thermal annealing of ion-implanted silicon  

International Nuclear Information System (INIS)

There have been several reports of transient-enhanced diffusion during furnace or rapid thermal annealing of ion-implanted silicon and some reports of no enhancement. In this contribution, the authors show that many of the observed effects can be accounted for by an interstitial trapping mechanism, in which large numbers of Si atoms are trapped by group V dopant atoms in the amorphous material during implantation. These trapped atoms are retained during solid-phase-epitaxial (SPE) growth, but can be released later during thermal processing to give the transient-enhanced diffusion. The authors present a model which can predict the transient effects (or lack of them) for any concentration of Sb, Bi, or As dopants sufficient to amorphize the silicon and any thermal processing technology which relies on SPE growth (furnace, cw laser, or rapid thermal annealing).

1985-03-01

390

Partnerships for Research and Education in Materials (PREM  

Science.gov (United States)

... Materials (PREM) Synopsis of Program: The objective of PREM is to enhance diversity in materials ... careers in materials research. The Partnerships for Research and Education in Materials (PREM ...

391

Partnerships for Research and Education in Materials  

Science.gov (United States)

... Materials (PREM) Synopsis of Program: The objective of PREM is to enhance diversity in materials ... careers in materials research.The Partnerships for Research and Education in Materials (PREM ...

392

PET imaging of tumour hypoxia  

UK PubMed Central (United Kingdom)

Tumour hypoxia represents a significant challenge to the curability of human tumours leading to treatment resistance and enhanced tumour progression. Tumour hypoxia can be detected by non-invasive and...Full Text Available

393

Neurocysticercosis  

UK PubMed Central (United Kingdom)

A single enhancing lesion in the brain parenchyma, also called an inflammatory granuloma, is a frequent neurologic diagnosis. One of the commonest causes of this lesion is human neurocysticercosis,...Full Text Available

2010-08-17

394

Microbial enhanced oil recovery: Entering the log phase  

Energy Technology Data Exchange (ETDEWEB)

Microbial enhanced oil recovery (MEOR) technology has advanced internationally since 1980 from a laboratory-based evaluation of microbial processes to field applications. In order to adequately support the decline in oil production in certain areas, research on cost-effective technologies such as microbial enhanced oil recovery processes must focus on both near-term and long-term applications. Many marginal wells are desperately in need of an inexpensive improved oil recovery technology today that can assist producers in order to prevent their abandonment. Microbial enhanced waterflooding technology has also been shown to be an economically feasible technology in the United States. Complementary environmental research and development will also be required to address any potential environmental impacts of microbial processes. In 1995 at this conference, the goal is to further document and promote microbial processes for ...

1995-12-31

395

Methylisothiazolinone contact allergy and dose-response relationships  

DEFF Research Database (Denmark)

Methylisothiazolinone (MI) used alone is a new preservative causing a high prevalence of contact allergy. The eliciting threshold of MI is unknown. The combination of MI and phenoxyethanol enhances the antimicrobial efficacy of MI.

2011-01-01

396

Magic-angle-spinning NMR studies of acid sites in zeolite H-ZSM-5  

Science.gov (United States)

{sup 1}H, {sup 13}C, {sup 27}Al, and {sup 29}Si magic-angle-spinning (MAS) NMR was used to elucidate the nature of the catalytic activity of zeolite H-ZSM-5. {sup 1}H MAS NMR of sealed samples after mild hydrothermal dealumination shows that the enhanced activity for n-hexane cracking is not due to an enhanced Bronstead acidity. The concentrations of the various OH groups and aluminous species suggest that the reason for the enhanced catalytic activity is the interaction of the n-hexane molecule with a bridging hydroxyl group and with extra-framework aluminium species, which give rise to the enhanced activity, cannot be easily removed from their positions, and are therefore immobilized by the zeolitic framework.

1991-01-01

397

Lipid Peroxidation and Antioxidant Defense ... - LSDA - Experiment  

Science.gov (United States)

Apr 21, 2011 ... The system of lipid peroxidation reacts regularly to adverse effects and results in enhancement of lipid peroxidation and build-up of LPO ...

398

LiF enhanced nucleation of the low temperature microcrystalline silicon prepared by plasma enhanced chemical vapour deposition  

Energy Technology Data Exchange (ETDEWEB)

A 15-nm lithium fluoride (LiF) thin film evaporated on glass substrate is shown to enhance the nucleation of microcrystalline Si grown by plasma enhanced chemical vapour deposition at the amorphous/microcrystalline boundary conditions. The effect is more pronounced at low substrate temperatures, nucleation density being 10 times higher at {approx} 80 {sup o}C. The effect is ascribed to the ionic chemical nature of LiF, the low work function material used in organic electronic devices, and we propose its use for micro patterning crystalline Si regions in otherwise amorphous Si film.

2009-10-30

399

Imaging oxygenation of human tumours  

UK PubMed Central (United Kingdom)

Tumour hypoxia represents a significant challenge to the curability of human tumours leading to treatment resistance and enhanced tumour progression. Tumour hypoxia can be detected by non-invasive and...Full Text Available

2007-04-01

400

Hypoxia and Magnetic Therapy for Personnel Radiation Protection  

International Science & Technology Center (ISTC)

Development of Portable Normobaric Hypoxia and Pulsed Magnetic Field Firmware System for Enhancement of Radio- and Non-specific Resistance in Workers of Environmentally Hazardous Industries

401

Hypothyroidism Enhances Tumor Invasiveness and Metastasis Development  

UK PubMed Central (United Kingdom)

BackgroundWhereas there is increasing evidence that loss of expression and/or function of the thyroid hormone receptors (TRs) could result in a selective advantage for tumor development,...Full Text Available

402

Examination of Iotophoretic Transport of Ionic Drugs across ...  

Science.gov (United States)

... derived and which describes fundamentally flux enhancement across an artificial membrane or skin: Keywords: Transdermal drug delivery system. ...

1986-07-30

403

Enzymatic engineering of the porcine genome with transposons and recombinases  

UK PubMed Central (United Kingdom)

BackgroundSwine is an important agricultural commodity and biomedical model. Manipulation of the pig genome provides opportunity to improve production efficiency, enhance disease...Full Text Available

404

Enhancing AIS to Improve Whale-Ship Collision Avoidance ...  

Science.gov (United States)

... 2008. Characterizing the relative contributions of large vessels to total ocean noise fields: a case study using the Gerry E. Studds Stellwagen Bank ...

2010-06-01

405

Enhancement of Keratinocyte Differentiation by Rose Absolute Oil  

UK PubMed Central (United Kingdom)

BackgroundThrough differentiation processes, keratinocytes provide a physical barrier to our bodies and control skin features such as moisturization, wrinkles and pigmentation. Keratinocyte...Full Text Available

2010-08-01

406

Enhanced diffusion from interstitial trapping during solid-phase-epitaxial growth of silicon alloys. Draft  

Energy Technology Data Exchange (ETDEWEB)

During the recrystallization by solid-phase-epitaxial (SPE) growth of supersaturated silicon alloys, a high concentration of interstitials is trapped. These are released by subsequent heating causing a transient (greatly enhanced) diffusion of the substitutional dopant by an interstitialcy mechanism. The enhancement may be as much as five orders of magnitude over tracer values, and shows an activation energy of only 1.8 +- 0.2 eV. Following the transient, the interstitials condense into loops, allowing an independent estimate to be made of their concentration. From these observations, we propose that during ion implantation, a fraction of the implanted dopants can acquire their natural valency, and retain it as the crystallization interface passes. For group V dopants this creates the trapped interstitials, giving transient enhanced diffusion when they are released by subsequent annealing.

1984-08-01

407

Enhanced diffusion from interstitial trapping during solid-phase-epitaxial growth of silicon alloys  

Energy Technology Data Exchange (ETDEWEB)

During the recrystallization by solid-phase-expitaxial (SPE) growth of supersaturated silicon alloys, a high concentration of interstitials is trapped. These are released by subsequent heating causing a transient (greatly enhanced) diffusion of the substitutional dopant by an interstitialcy mechanism. The enhancement may be as much as five orders of magnitude over tracer values, and shows an activation energy of only 1.8 +/- 0.2 eV. Following the transient, the interstitials condense into loops, allowing an independent estimate to be made of their concentration. From these observations, it is proposed that during ion implantation, a fraction of the implanted dopants can acquire their natural valency, and retain it as the crystallization interface passes. For group V dopants this creates the trapped interstitials, giving transient enhanced diffusion when they are released by subsequent annealing. 12 references, 6 figures.

1984-01-01

408

Enhanced Reliability MEMS Deformable Mirrors for Space Imaging ...  

Science.gov (United States)

Sep 3, 2010 ... These higher-quality deformable mirrors will enable diffraction-limited performance for many space-based optical systems such as space-based ...

409

Enhanced Algorithms for EO/IR Electronic Stabilization, Clutter ...  

Science.gov (United States)

... coordinates to allow for multisensor fusion, trajectory ... of an image processing toolkit (iPTK ... effectiveness of data-driven registration processing, spatial ...

2009-09-01

410

Enhanced Aircraft Design Capability for the Automated ...  

Science.gov (United States)

... The third series used a correlated parameter covariance matrix derived from a generic database of modeling uncertainty for space structures [5-1 ...

1996-01-31

411

Effect of recoil implantation of oxygen on boron enhanced diffusion in silicon  

International Nuclear Information System (INIS)

In device fabrication, dopants are frequently implanted into silicon through silicon dioxide masks. A consequence of this technique is the co-implantation of recoiled oxygen into the substrate. This study investigates the effect of recoiled oxygen on the widely observed transient enhanced boron diffusion. Comparison of the spreading resistance profiles of annealed through-oxide and directly implanted samples reveals that transient enhanced diffusion of boron can be suppressed by the former process. Continued annealing of the through-oxide implanted silicon recovers the enhanced diffusion of boron. This behavior is believed to be due to precipitation of recoiled oxygen. The mechanisms leading to the above observations are discussed and transmission electron microscopy support presented. 11 refs., 5 figs.

1989-04-25

412

Development Of Very-High-Strength and High-Performance ...  

Science.gov (United States)

... High performance concrete doesn't always refer to enhanced strength, as in the case of VHSC. ... Composite Materials VHSC Concrete ...

2004-12-01

413

Dense and diffuse gas in dynamically active clouds  

CERN Document Server

We investigate the chemical and observational implications of repetitive transient dense core formation in molecular clouds. We allow a transient density fluctuation to form and disperse over a period of 1 Myr, tracing its chemical evolution. We then allow the same gas immediately to undergo further such formation and dispersion cycles. The chemistry of the dense gas in subsequent cycles is similar to that of the first, and a limit cycle is reached quickly (2 - 3 cycles). Enhancement of hydrocarbon abundances during a specific period of evolution is the strongest indicator of previous dynamical history. The molecular content of the diffuse background gas in the molecular cloud is expected to be strongly enhanced by the core formation and dispersion process. Such enhancement may remain for as long as 0.5 Myr. The frequency of repetitive core formation should strongly determine the level of background molecular ...

2006-01-01

414

Cryogenic trick for enhanced cooling using liquid nitrogen  

International Nuclear Information System (INIS)

The thermal transpiration method has been employed to replace the temperature of liquid nitrogen by #approx#12 K. This is done by bubbling He (g) through the liquid nitrogen.

1993-01-01

415

Boron enhanced diffusion due to high energy ion-implantation and its suppression by using RTA process  

Energy Technology Data Exchange (ETDEWEB)

SIMS measurements revealed that high energy boron-implantation causes transient enhanced diffusion (TED) of a shallow dopant profile due to Si interstitials even for a relatively low dose of {approximately}2E13cm{sup {minus}2}. By systematic analysis, it is found that this anomalous diffusion is most significant in 700--800 C annealing, and it takes place in the initial stage (less than 30 sec for 800 C) of annealing. Moreover, this anomalous diffusion is more considerable than the enhanced diffusion during oxidation (OED) in practical device fabrication processes. It is found that rapid thermal annealing (RTA) at 1,000--1,100 C is effective for suppressing the transient enhanced diffusion and realizing a shallow channel profile for deep sub-micron devices.

1995-12-31

416

Boron enhanced diffusion due to high energy ion-implantation and its suppression by using RTA process  

International Nuclear Information System (INIS)

SIMS measurements revealed that high energy boron-implantation causes transient enhanced diffusion (TED) of a shallow dopant profile due to Si interstitials even for a relatively low dose of #approx#2E13cm"-"2. By systematic analysis, it is found that this anomalous diffusion is most significant in 700--800 C annealing, and it takes place in the initial stage (less than 30 sec for 800 C) of annealing. Moreover, this anomalous diffusion is more considerable than the enhanced diffusion during oxidation (OED) in practical device fabrication processes. It is found that rapid thermal annealing (RTA) at 1,000--1,100 C is effective for suppressing the transient enhanced diffusion and realizing a shallow channel profile for deep sub-micron devices.

417

Assessment, development and coordination of technology base studies in enhanced heat transfer. Quarterly progress report No. 7, March 1, 1983-May 31, 1983  

Energy Technology Data Exchange (ETDEWEB)

The major goal of this continuation project is to advance the utilization of heat transfer enhancement techniques in commercial heat exchange equipment. Thirteen heat transfer enhancement techniques have been identified as having potential for improving heat transfer coefficients in full-scale industrial equipment. The following tasks are part of this project, which was originally planned for three years: (1) expansion of technology information base; (2) evaluation of performance of enhanced surfaces and inserts; (3) correlation of data for spirally fluted surfaces; (4) study of structured surfaces in pool boiling; and (5) study of structured surface in spray film evaporation.

1983-08-01

418

Antimicrobial activity and mechanism of action of Nu-3, a protonated modified nucleotide  

UK PubMed Central (United Kingdom)

Background"Nubiotics" are synthetic oligonucleotides and nucleotides with nuclease-resistant backbones, and are fully protonated for enhanced ability to be taken up by bacterial...Full Text Available

419

Absorption of plutonium in the iron-deficient rat  

International Nuclear Information System (INIS)

Iron deficiency did not enhance absorption of plutonium following intragastric gavage of rats. Absorption of plutonium citrate in both control and iron-deficient rats was about 0.03% of the administered dose.

1977-05-01

420

A note on the flow and heat transfer enhancement in a channel with built-in winglet pair  

International Nuclear Information System (INIS)

Counter rotating longitudinal vortices produced by winglet in a channel are known to enhance heat transfer. In the present investigation the flow structure and heat-transfer enhancement by a winglet pair of non-zero thickness has been studied. A delta winglet pair type vortex generator is placed in a hydrodynamically developed and thermally developing laminar channel flow. Computations are done by solving the unsteady, three-dimensional, incompressible Navier-Strokes equations and energy equation using a modified Marker-and-Cell (MAC) method. The flow structure is complex and consists of main, corner and induced vortices. It is observed that as compared to a channel without winglets, the heat transfer is enhanced by 33% when single winglet is used and by 67% when a winglet pair is employed. Effects of thickness of the winglets and Reynolds number on the heat transfer augmentation are presented.

2007-04-01

421

A Cyanobacterial Circadian Clockwork  

UK PubMed Central (United Kingdom)

Cyanobacteria have become a major model system for analyzing clock phenomena. The temporal program in this organism enhances fitness in rhythmic environments and is truly global—essentially...Full Text Available

2008-09-09

422

Wind instability of a foam layer sandwiched between the atmosphere and the ocean  

CERN Document Server

Kelvin-Helmholtz instability of short gravity waves is examined in order to explain the recent findings of the decrease in momentum transfer from hurricane winds to sea waves. A three-fluid configuration of a foam layer between the atmosphere and the ocean is suggested to provide signifficant stabilization of the system and shifting the marginal critical wavelength to the shortwave part of the spectrum. It is conjectured that such stabilization leads to the observed drag reduction. The high contrasts in three fluid densities provide a universal mechanism for stabilizing surface perturbations.

2007-01-01

423

Variosorb - advanced gas sorption with powder sorbent technology  

Energy Technology Data Exchange (ETDEWEB)

In contrast to plants based on formed coal where, for the purposes of calculating sorbent volume, only one activated charcoal design can be used in a filter layer, powder sorbent technology enables two variations to be used. This can be either a mixture of a number of different activated charcoal forms in one and the same filter layer, or the combination of a number of filter layers on top of each other, each containing a different activated charcoal form, in one and the same construction unit.

1983-01-01

424

The different structural scales of the breast and their impact on time-of-flight and diffraction tomography  

Energy Technology Data Exchange (ETDEWEB)

Ultrasound tomography is an attractive imaging method for the detection of breast cancer. The complex anatomy of the breast with its different spatial scales and material property contrasts make accurate reconstructions very challenging. This paper proposes a hybrid approach whereby Travel-of-Flight and Diffraction Tomography are combined together to achieve high-resolution and high-accuracy sound-speed reconstructions. The method is validated with several numerical phantoms.

2010-01-01

425

The Percus-Yevick theory is alive and well  

Science.gov (United States)

The pressure of a 6:12 fluid is obtained from the Percus-Yevick theory at the temperature kT/? = 1.35. The energy equation results are in excellent agreement with machine calculation results in contrast to the pressure and compressibility equation results. Present address: Diffusion Research Unit, The Australian National University, Canberra, ACT, Australia.

1970-01-01

426

Simulations of dual morphology in spiral galaxies  

CERN Document Server

Gas and stars in spiral galaxies are modelled with the DUAL code, using hydrodynamic and N-body techniques. The simulations reveal morphological differences mirroring the dual morphologies seen in B and K' band observations of many spiral galaxies. In particular, the gaseous images are more flocculent with lower pitch angles than the stellar images, and the stellar arm-interarm contrast correlates with the degree of morphological decoupling.

2003-01-01

427

Quantum tachyons in Schwarzschild space-time  

Energy Technology Data Exchange (ETDEWEB)

The wave equation of a spinless tachyon is studied in Schwarzschild space-time. In contrast to earlier approaches to the problem, it is shown that tachyonic static solutions satisfy a simple second-order linear differential equation regardless of the mass of the black hole and the mass parameter of the tachyon. Physical implication of the present approach is discussed. Using Langer modification of the WKB (Wentzel-Kramers-Brillouin) boundary condition an expression similar to the Bohr-Sommerfeld quantization condition is derived.

1981-02-01

428

Prolactin and Its Receptor Are Expressed in Murine Hair Follicle Epithelium, Show Hair Cycle-Dependent Expression, and Induce Catagen  

UK PubMed Central (United Kingdom)

Here, we provide the first study of prolactin (PRL) and prolactin receptor (PRLR) expression during the nonseasonal murine hair cycle, which is, in contrast to sheep, comparable with the human scalp...Full Text Available

2003-05-01

429

Phase-plate electron microscopy: a novel imaging tool to reveal close-to-life nano-structures  

UK PubMed Central (United Kingdom)

After slow progress in the efforts to develop phase plates for electron microscopes, functional phase plate using thin carbon film has been reported recently. It permits collecting high-contrast images...Full Text Available

2009-03-01

430

Non-selective cervical and cerebral three-dimensional rotational angiography  

International Nuclear Information System (INIS)

To evaluate the usefulness of three-dimensional (3D) rotational angiography, cervical carotid or cerebral angiography was done without catheterizing the branches of the thoracic aorta. A 5-Fr pig-tail type catheter was passed into the ascending aorta via the radial artery or the femoral artery. Optimal carotid angiogram views were obtained using approximately 45 ml of contrast medium at a flow rate of 15 ml/sec. Optimal cerebral angiogram views were obtained using approximately 70 ml of contrast medium at a flow rate of 20 ml/sec. The contrast medium concentration was 300 to 350 mgI/ml. A satisfactory view could be obtained in 5 of 8 (63%) cases on cervical carotid 3D angiography and in 8 of 14 (57%) cases on cerebral 3D angiography. In all cases, no complications were noted. This method offers the advantages of requiring a relatively short procedure time and a decrease in radiation exposure. Further studies are needed to ...

2007-09-01

431

Neutron radiography with the cyclotron, 6  

International Nuclear Information System (INIS)

The image processing system for the dynamic neutron radiography has been developed. It is based on the hardware subset, composed by the method of the pipe-line and use of algorithm of local statistics. The processing speed per one pixel is shorter than 100 n sec and video-rate processing can be executed on it. Some image processes for improving the quality of the real-time neutron image, noise reduction and contrast stretching would be attempted by the use of this system. (author).

1988-01-01

432

Modeling Transient Discharge into a Tunnel Drilled in a Heterogeneous Formation  

British Library Electronic Table of Contents (United Kingdom)

Abstract An analytical model is developed to predict transient discharge flow into a tunnel drilled at various speeds through a heterogeneous formation. This model relies on simplifying assumptions commonly enforced in hydrogeologic engineering, and combines the convolution and superposition principles to account for composite sections with arbitrary parametric contrasts. An application to the data monitored during the exploratory drilling of an Alpine tunnel confirms the validity of the approach.

2007-01-01

433

Measurement of the Self-Diffusion Coefficient of Water as a Function of Position in Wheat Grain Using Nuclear Magnetic Resonance Imaging  

UK PubMed Central (United Kingdom)

A pulsed field gradient spin echo sequence has been incorporated in a nuclear magnetic resonance (NMR) imaging experiment to provide an image contrast dependent on local molecular self-diffusion. The...Full Text Available

1988-01-01

434

Maximum imaging depth of two-photon autofluorescence microscopy in epithelial tissues  

Science.gov (United States)

Endogenous fluorescence provides morphological, spectral, and lifetime contrast that can indicate disease states in tissues. Previous studies have demonstrated that two-photon autofluorescence microscopy (2PAM) can be used for noninvasive, three-dimensional imaging of epithelial tissues down to approximately 150 ?m beneath the skin surface. We report ex-vivo 2PAM images of epithelial tissue from a human tongue biopsy down to 370 ?m below the surface. At greater than 320 ?m deep, the fluorescence generated outside the focal volume degrades the image contrast to below one. We demonstrate that these imaging depths can be reached with 160 mW of laser power (2-nJ per pulse) from a conventional 80-MHz repetition rate ultrafast laser oscillator. To better understand the maximum imaging depths that we can achieve in epithelial tissues, we studied image contrast as a function of depth in tissue phantoms with a range of relevant ...

2011-02-01

435

MAGNETIC ELECTRON MICROSCOPE UEMB-100  

Science.gov (United States)

A new magnetic electron microscope, UEMB-100, was designed with an increased electron-optical parameter. The electron-optical system consists of an electron canon (the high voltage is supplied by armored lead) and condensed, objective, intermediate, and projection lenses. In contrast to other native apparatuses, the microscope has a high resolving property (up to 20A) snnd great universality. (tr-auth)

1958-07-01

436

Lung studies with spiral CT. pitch 1 versus pitch 2  

International Nuclear Information System (INIS)

In Spiral CT, the pitch is the ratio of the distance to tabletop travels per 360 degrees rotation to nominal slice width, expressed in mm. Performing Spiral CT examination with pitch 2 allows to reduce examination time, exposure and contrast dose, and X-ray tube overload. The authors investigated the yield of pitch 2 in lung parenchyma studies, particular relative to diagnostic image quality.

1999-03-01

437

Laser weapons. II - Strategic laser weapons  

Science.gov (United States)

Potential strategic missions for laser weapons, particularly those involving space-based lasers, are discussed. The functions of space-based lasers and the history of their conceptual development are summarized, and the problems of implementing such systems, including the building of a suitable laser and power source, and resolving the problem of optics, are discussed. Ongoing development programs are described, and the contrasting views of the necessity and usefulness of strategic laser systems are set forth.

1982-07-01

438

Kinetic estimation of infused Lipiodol within hepatoma using CT dynamic study  

Energy Technology Data Exchange (ETDEWEB)

Distribution of Lipiodol within hepatic tumor was evaluated using serial computed tomography. Imagistic Lipiodol transition into the tumor via hepatic artery was slower than that of water soluble contrast medium, spreading to central part first and turn to peripheral part of the tumor. This method was thought to be useful to clarify Lipiodol distribution in hepatic tumor and to decide the method or necessity of additional trans-arterial therapy. (author).

1991-02-01

439

Instantaneous energy density as a feature for gear fault detection  

Science.gov (United States)

In this work, energy-based features for gear fault diagnosis and prediction are proposed. The instantaneous energy density is shown to obtain high values when defected teeth are engaged. Three methods are compared in terms of sensitivity, reliability and computation effectiveness. The Wigner Ville distribution is contrasted to the wavelet transform and the newly proposed empirical mode decomposition scheme. It is shown that all three methods are capable of a reliable prediction. An empirical law, which relates the energy content to the crack magnitude is established.

2006-07-01

440

Implications of biodiversity of short rotation coppice  

Environmental Research Database

DescriptionFossil fuels have a detrimental effect on the environment. They lead to the increase in atmospheric carbon dioxide which has been documented over the last 150 years. In contrast, some sources of renewable energy are near carbon neutral. Renewable energy produced from biomass constitutes such a type of energy and so has many potential advantages. The Energy White Paper (DTI et al., 2003) identifies bioenergy as an important means of meeting the Government's energy and environment objectives, in [continued...

2009-01-31

441

IDEAS: Journal of International Trade & Economic Development, Taylor and Francis Journals  

Wastenet

... (restricted)] 101-127 On the transmission of exchange rate fluctuations to the macroeconomy: Contrasting evidence for developing and developed countries by Magda Kandil [Downloadable! (restricted)] 2005, Volume 14, Issue 4 377-405 Predicting the poverty impacts of trade reform by Thomas Hertel & Jeffrey Reimer [Downloadable! (restricted)] 407-435 Sustaining imperfectly credible trade liberalization: Do the rate of tariff reduction ...

442

How to decorate FIB cross sections using plasma etch for SEM observation  

Energy Technology Data Exchange (ETDEWEB)

The Focused-Ion-Beam (FIB) is a powerful tool for fast, precision cross-sectioning and inspection of submicron defects in multilayered integrated circuit devices. However, the low contrast between the layers in FIB cross-sections can make the feature of interest difficult to observe, which has become a limitation for FIB cross-sectioning. A technique using plasma etch to decorate the FIB cross-sections has proven to be a simple solution to overcome this limitation.

1995-12-31

443

Geosynchronous orbit magnetopause crossings  

Energy Technology Data Exchange (ETDEWEB)

In this study we extend the analysis of magnetopause crossings observed with Magnetospheric Plasma Analyzer measurements to examine a much larger statistical data set. This study examines 39 maiznetosheath/LLBL intervals from 79 spacecraft-months of observations: these observations were taken from a survey of data from the start of each spacecraft mission and extending through March 1993. In contrast to the previous findings, we find no evidence for a significant dawn/dusk asymmetry in geosynchronous magnetopause crossings.

1994-07-01

444

Features of laser damage to elastic polymers  

Energy Technology Data Exchange (ETDEWEB)

Threshold pump intensity values leading to irreversible damage to colored laser elements based on elastic polymers were measured. The damage to colored elastomers is connected with absorbing microinclusions but is independent of molecular absorption. It is shown that damage to the elastomers has a pronounced threshold character in contrast to the microdamage accumulation effect in glassy polymers. The damage threshold for elastomers is 1.5 times higher, which is connected with the absence of microstresses (characteristics for organic glasses) in the specimens. 13 references.

1988-03-01

445

Extended superconformal algebra from super Toda field theory  

International Nuclear Information System (INIS)

We propose and construct a new type of extended superconformal algebra (ESA) based on the super Toda field theory. Both in the N = 1 ESA and in the N = 2 ESA, an arbitrary value of the central charge is allowed in contrast with the previously known super W-algebra. The generators of ESA are interpreted as the constants of motion in the super Toda field theory. (orig.).

1991-01-01

446

Evaluation of peripheral vascular disease by intravenous digital subtraction angiography with the Fuji computed radiography (FCR) system  

Energy Technology Data Exchange (ETDEWEB)

Intravenous digital subtraction angiography using Fuji computed radiography system (FCR-DSA) was used to evaluate 57 preoperative patients with clinical manifestations of peripheral vascular disease of lower extremity. With its high contrast resolution and good special resolution, image of FCR-DSA could offer optimal information of vascular abnormality in lower extremity distal to midfoot for the diagnosis and the choice of management.

1987-03-01

447

Evaluation of peripheral vascular disease by intravenous digital subtraction angiography with the Fuji computed radiography (FCR) system  

International Nuclear Information System (INIS)

Intravenous digital subtraction angiography using Fuji computed radiography system (FCR-DSA) was used to evaluate 57 preoperative patients with clinical manifestations of peripheral vascular disease of lower extremity. With its high contrast resolution and good special resolution, image of FCR-DSA could offer optimal information of vascular abnormality in lower extremity distal to midfoot for the diagnosis and the choice of management. (orig.).

1987-01-01

448

Equine infectious anemia virus and human immunodeficiency virus DNA synthesis in vitro: characterization of the endogenous reverse transcriptase reaction.  

UK PubMed Central (United Kingdom)

The endogenous reverse transcriptase reaction of equine infectious anemia virus (EIAV) has been studied, and conditions allowing synthesis of full-length minus-strand DNA have been determined. In contrast...Full Text Available

1991-04-01

449

Elucidating novel pathways and regulation of nitrogen assimilation in alpha proteobacteria exemplified by the soil organism Paracoccus denitrificans  

Environmental Research Database

DescriptionThe importance of inorganic nitrate for the nutrition and growth of marine and freshwater autotrophic phytoplankton has long been recognised, in particularly because of the 'blooms' formed in nitrate and phosphate polluted water and their possible roles as carbon dioxide sinks. By contrast, the utilisation of nitrate by heterotrophic bacteria has historically received less attention. Up until now, the primary role of heterotrophic bacteria has classically been considered to be the decomposition [continued...

2010-01-31

450

Controllable Subspaces of Open Quantum Dynamical Systems  

International Nuclear Information System (INIS)

This paper discusses the concept of controllable subspace for open quantum dynamical systems. It is constructively demonstrated that combining structural features of decoherence-free subspaces with the ability to perform open-loop coherent control on open quantum systems will allow decoherence-free subspaces to be controllable. This is in contrast to the observation that open quantum dynamical systems are not open-loop controllable. To a certain extent, this paper gives an alternative control theoretical interpretation on why decoherence-free subspaces can be useful for quantum computation.

2008-01-15

451

Computing Networks: A General Framework to Contrast Neural and Swarm Architectures  

CERN Document Server

Computing Networks (CNs) are defined. These are used to generalize neural and swarm architectures, namely artificial neural networks, ant colony optimization, and particle swarm optimization. The description of these architectures as CNs allows their comparison, distinguishing which properties enable them to perform complex computations and exhibit complex cognitive abilities. In this context, the most relevant characteristics of CNs are the existence multiple dynamical and functional scales.

2010-01-01

452

Collaborations in Mind, Brain, and Education: An Analysis of Researcher-Practitioner Partnerships in Three Elementary School Intervention Studies  

British Library Electronic Table of Contents (United Kingdom)

A reciprocal relationship informing both research and practice is one of the primary goals in the emerging field of Mind, Brain, and Education (MBE), yet the field has little documentation and analysis of such collaborations. In this article, we present case studies of three research-practice partnerships taking place between scientists and educators. By comparing and contrasting these three partnerships we expect to illuminate common characteristics, challenges, and benefits that come with doing MBE work.

2011-01-01

453

Campylobacter jejuni Fatty Acid Synthase II: Structural and functional analysis of ?-hydroxyacyl-ACP dehydratase (FabZ)  

UK PubMed Central (United Kingdom)

Fatty acid biosynthesis is crucial for all living cells. In contrast to higher organisms, bacteria use a type II fatty acid synthase (FAS II) composed of a series of individual proteins, making...Full Text Available

2009-03-06

454

Big is beautiful in biotechnology  

Energy Technology Data Exchange (ETDEWEB)

Venture capital has guaranteed the successful launch of biotechnology in the US since 1977. Established companies are then licensed to produce and distribute the latest inventions. By contrast in Japan established industrial companies are the leaders in biotechnology research, development and commercialization, building on existing technology and past experience and retraining staff. In the US electronics industry the acute shortage of electronic engineers combined with the high cost of capital and instability within venture capital companies to restrict the high level of innovation required looks likely to happen again in biotechnology.

1984-01-01

455

Adiabatic theory of Wannier threshold laws and ionization cross sections  

Energy Technology Data Exchange (ETDEWEB)

The Wannier threshold law for three-particle fragmentation is reviewed. By integrating the Schroedinger equation along a path where the reaction coordinate R is complex, anharmonic corrections to the simple power law are obtained. These corrections are found to be non-analytic in the energy E, in contrast to the expected analytic dependence upon E.

1994-12-31

456

A predictive integrated voltage regulator and power system stabilizer  

Energy Technology Data Exchange (ETDEWEB)

An integrated voltage regulator and power system stabilizer based on one step ahead prediction is presented. The fixed parameter predictive control scheme is shown capable of providing consistently good voltage response and contribution to system damping over a wide range of operating conditions and system configuration. This is in contrast to the case with conventional automatic voltage regulator and power system stabilizer where performance varies widely with the operating situation and can even cause system instability. (author)

1995-04-01

457

A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice  

UK PubMed Central (United Kingdom)

Amyloid plaques are a characteristic feature in Alzheimer’s disease (AD). A novel non-toxic contrast agent is presented, Gd-DTPA-K6Aβ1–30, which is homologous to Aβ,...Full Text Available

2008-06-01

458

#sigma#_e_e_#gamma#_#gamma#"t"o"t at e"+e"- colliders  

International Nuclear Information System (INIS)

In this talk I briefly summarize different models for #sigma#_2_#gamma#"t"o"t (e"+e"-#->##gamma##gamma##->#hadrons) and contrast model predictions with the data. I will then discuss the capability of the future e"+e"- and #gamma##gamma# colliders to distinguish between various models and end with an outlook for future work.

2001-07-09

459

A search for. nu. sub e appearance from stopped. pi. sup + and. mu. sup + decay at LAMPF (Los Alamos Meson Physics Facility)  

Energy Technology Data Exchange (ETDEWEB)

We report on a recent search for {bar {nu}}{sub e} appearance from stopped {pi}{sup +} {yields} {mu}{sup +}{nu}{sub {mu}} and {mu}{sup +} {yields} e{sup +}{nu}{sub e}{bar {nu}}{sub {mu}} decay made by the LAMPF experiment E645. The appearance of {bar {nu}}{sub e} may occur from {bar {nu}}{sub {mu}} {yields} {bar {nu}}{sub e}, {nu}{sub e} {yields} {bar {nu}}{sub eL}, or {nu}{sub {mu}} {yields} {bar {nu}}{sub eL} oscillations. Appearance may also occur from rare {mu}{sup +} {yields} e{sup +}{bar {nu}}{sub e}{nu}{sub {mu}} decay, which is allowed by a multiplicative lepton charge conservation law. The neutrino energies range from E{sub {nu}} = 0 to 52.8MeV. The neutrino detector, which is located 26.1 meters from the neutrino source, consists of a segmented liquid scintillator and proportional drift tube central detector surrounded by both active and passive shielding. The central detector detects {bar {nu}}{sub e} through the {bar {nu}}{sub e}p {yields} ne{sup +} Charge Current (CC) ...

1990-01-01

460

miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NF?B1  

UK PubMed Central (United Kingdom)

The activation of nuclear factor-kappa B1 (NFκB1) in cancer cells may confer resistance to ionizing radiation (IR). To enhance the therapeutic efficiency of IR in lung cancer, we screened for...Full Text Available

2011-05-31

461

The development and testing of emissivity enhancement coatings for thermophotovoltaic (TPV) radiator applications  

Energy Technology Data Exchange (ETDEWEB)

One requirement of a thermophotovoltaic (TPV) radiator is to efficiently emit photons at high temperatures to TPV cells for conversion to electric power. Because many candidate radiator materials with adequate structural properties display low emissivity, coatings or other surface modifications are required for enhancement of emissivity. Six plasma sprayed coatings and one textured surface demonstrated adequate thermal stability and emittance values of 0.8 or greater. Promising attributes of modified surfaces are identified.

1999-03-01

462

Some problems to enhance reliability and safety of foreign NPP  

International Nuclear Information System (INIS)

Statistical data on individual types of foreign NPPs including reliability and safety indices are given. It is noted that capacity factors (CF) in 1985 were higher for PWRs. Japan has the highest CF-98.5% in the world. One of main causes of NPP shutdown remains the primary circuit equipment failure in connection with different corrosion types (intercrystalline, pitting, denting-corrosion etc.). Effect of all volatile treatment on enhancement of NPP reliabiity is shown. Technical BWR characteristics are presented.

463

Radiochemical and Raman spectroscopy study of the nature of adsorbed layers on a silver electrode  

International Nuclear Information System (INIS)

The structure of the layers formed on a silver electrode by the adsorption of pyridine, Cl"-, CN"- and SO_4"2"- is discussed. A comparison of the amount of the species adsorbed with their Raman spectra shows that there is no simple relation between the species concentration and the enhancement of the Raman intensity. Furthermore, the inhomogeneity of the layers is shown by Raman microscopy observations. These results lead the authors to propose the formation of a new species stabilized in the colloidal silver layer. The Raman enhancement could be explained by the existence of a resonance effect. (Auth.).

464

New physics effects on Higgs production at #gamma##gamma# colliders  

International Nuclear Information System (INIS)

We study heavy physics effects on the Higgs production in #gamma##gamma# fusion using the effective Lagrangian approach. We find that the effects coming from new physics may enhance the standard model predictions for the number of events expected in the final states b-barb, WW, and ZZ up to one order of magnitude, whereas the corresponding number of events for the final state t-bart may be enhanced up to two orders of magnitude.

1996-02-20

465

Monocyte responses to sulfatide from Mycobacterium tuberculosis: inhibition of priming for enhanced release of superoxide, associated with increased secretion of interleukin-1 and tumor necrosis factor alpha, and altered protein phosphorylation.  

UK PubMed Central (United Kingdom)

In monocytes, sulfatide, a lipid from Mycobacterium tuberculosis, blocked priming for enhanced release of superoxide (O2-) by the macrophage activating factors lipopolysaccharide, gamma interferon,...Full Text Available

1991-08-01

466

Mice With a Deletion in the Gene for CCAAT/Enhancer-Binding Protein ? are Protected Against Diet-Induced Obesity  

UK PubMed Central (United Kingdom)

The CCAAT/enhancer-binding protein β (C/EBPβ) is required for adipocyte differentiation and maturation. We have studied the role of the transcription factor, C/EBPβ,...Full Text Available

2007-01-01

467

Image-enhancement applications at the Lawrence Livermore National Laboratory  

Energy Technology Data Exchange (ETDEWEB)

A diverse set of digital image-processing applications exists at the Lawrence Livermore National Laboratory. While many of these include some sort of image analysis or restoration, virtually all of them require image-enhancement procedures. In this paper we describe the principal image-processing facility at the Laboratory, followed by a discussion of several of the major image-processing application areas.

1982-06-01

468

Full potential all electron positron lifetime calculations: assessment of local enhancement factors  

International Nuclear Information System (INIS)

We report the implementation of positron wave function and lifetime calculations in the all-electron full-potential linearized augmented plane wave method. Calculations of lifetimes for more than 30 materials with two different forms of the enhancement factor were done and compared to prior calculations and experiment. We find that reasonable agreement with experiment can be obtained within the local density approximation when all-electron full-potential calculations are done.

2008-04-01

469

Enhanced heat transfer through oscillatory flow  

Energy Technology Data Exchange (ETDEWEB)

The enhancement of longitudinal heat transfer by means of fluid pulsation in a pipe has been investigated analytically and numerically, including the transient state. The effects of pulsation amplitude, frequency, and pipe length on thermal properties such as effective thermal diffusivity and delay time are clarified. Their effects on numerical calculations are also presented and suggestions for efficient numerical calculations of this problem are made concerning the combination of parameters.

1994-03-01

470

Enhanced glycemic responsiveness to epinephrine in insulin-dependent diabetes mellitus is the result of the inability to secrete insulin. Augmented insulin secretion normally limits the glycemic, but not the lipolytic or ketogenic, response to epinephrine in humans.  

UK PubMed Central (United Kingdom)

To determine if the enhanced glycemic response to epinephrine in patients with insulin-dependent diabetes mellitus (IDDM) is the result of increased adrenergic sensitivity per se, increased glucagon...Full Text Available

1985-06-01

471

ECONOMICS OF RETROFITTING BIG RIVERS ELECTRIC CORPORATION'S LIME-BASED FGD (FLUE GAS DESULFURIZATION) SYSTEM TO ORGANIC-ACID-ENHANCED LIMESTONE OPERATIONS  

Science.gov (United States)

The report describes the site specific changes required to convert an existing lime FGD system to a limestone system enhanced by dibasic acid (DBA) or adipic acid, and the costs of making such a change. In 1982-83, pilot plant tests were conducted at the R. D. Green Station of Bi...

472

DEVELOPMENT AND PILOT PLANT EVALUATION OF SILICA-ENHANCED LIME SORBENTS FOR DRY FLUE GAS DESULFURIZATION (JOURNAL VERSION)  

Science.gov (United States)

The paper discusses recent work on lime enhancement and testing at the bench-scale, followed by evaluation of the more promising sorbents in a pilot plant to develop low cost, retrofittable flue gas cleaning technology specifically the development of highly reactive sorbents. Con...

473

Boron uphill diffusion during ultrashallow junction formation  

International Nuclear Information System (INIS)

The recently observed phenomenon of boron uphill diffusion during low-temperature annealing of ultrashallow ion-implanted junctions in silicon has been investigated. It is shown that the effect is enhanced by preamorphization, and that an increase in the depth of the preamorphized layer reduces uphill diffusion in the high-concentration portion of boron profile, while increasing transient enhanced diffusion in the tail. The data demonstrate that the magnitude of the uphill diffusion effect is determined by the proximity of boron and implant damage to the silicon surface.

2003-05-26

474

Annual Report on Wildlife Activities, 1985 Fiscal Year, Action Item 40.1, Columbia River Basin Fish and Wildlife Program.  

Energy Technology Data Exchange (ETDEWEB)

The report presents a brief synopsis and discussion of wildlife activities undertaken by Bonneville Power Administration. The objectives of the program were wildlife protection, mitigation, and enhancement planning; and implementation of actions to protect, mitigate, and enhance wildlife affected by development and operation of hydroelectric facilities in the Columbia River Basin. (ACR)

1985-09-01

475

Anisotropic many-body effects in the quasiparticle velocity of Nb  

International Nuclear Information System (INIS)

Fermi radii and velocities are determined by deconvoluting de Haas-van Alphen data. Comparison of these data with accurate augmented-plane-wave band-structure results establishes the reliability of the augmented-plane-wave calculations and allows a determination of the anisotropic many-body enhancement factor lambda(k). The Fermi-surface average of 1.33 suggests a large electron-electron contribution. Our anisotropic lambda(k) porvides a detailed test and guide for model calculations of many-body enhancement.

476

Air-side flow and heat transfer in compact heat exchangers: A discussion of enhancement mechanisms  

Energy Technology Data Exchange (ETDEWEB)

The behavior of air flows in complex heat exchanger passages is reviewed with a focus on the heat transfer effects of boundary-layer development, turbulence, spanwise and streamwise vortices, and wake management. Each of these flow features is discussed for the plain, wavy, and interrupted passages found in contemporary compact heat exchanger designs. Results from the literature are used to help explain the role of these mechanisms in heat transfer enhancement strategies.

1998-10-01

477

Advances in enhanced heat transfer: 1987  

Energy Technology Data Exchange (ETDEWEB)

This book contains nine selections. Some of the titles are: High Heat-Flux, Forced-Convection Heat Transfer for Tubes with Twisted-Tape Inserts; Heat Transfer Augmentation by Interrupted Surfaces - Experimental Consideration; Turbulent Flow Heat Transfer from Externally Roughened Tubes in Axial Flow in Concentric Pipe Heat Exchangers; and Heat Transfer Enhancement of Turbulent Flow in Pipes with an Internal Circular Rib.

1987-01-01

478

Advances in enhanced heat transfer: 1987  

International Nuclear Information System (INIS)

This book contains nine selections. Some of the titles are: High Heat-Flux, Forced-Convection Heat Transfer for Tubes with Twisted-Tape Inserts; Heat Transfer Augmentation by Interrupted Surfaces - Experimental Consideration; Turbulent Flow Heat Transfer from Externally Roughened Tubes in Axial Flow in Concentric Pipe Heat Exchangers; and Heat Transfer Enhancement of Turbulent Flow in Pipes with an Internal Circular Rib.

1987-08-09

479

Transient enhanced diffusion of Sb and B due to MeV silicon implants  

Energy Technology Data Exchange (ETDEWEB)

We measure the transient enhanced diffusion of shallow molecular-beam-epitaxy grown marker layers of Sb and B due to deep MeV Si{sup +} ion implants at very high doses ({approx}10{sup 16}cm{sup {minus}2}). We expect the near-surface region of these implants to be vacancy rich, and we observe transient enhanced diffusion of Sb (the classic vacancy diffuser). The large enhancements imply a significant vacancy supersaturation ({approx}700 at 740{degree}C). Double implantation of the high-dose MeV Si followed by a shallow (40 keV) Si implant and annealing produces a greatly reduced number of {l_brace}311{r_brace} defects compared to a 40 keV implant into virgin Si, again consistent with a vacancy-rich region in the near-surface region of an MeV implant. However, the shallow B marker layers also show transient enhanced diffusion for the same MeV implant under similar annealing conditions, implying that an ...

1997-06-01

480

Transient enhanced diffusion of Sb and B due to MeV silicon implants  

International Nuclear Information System (INIS)

We measure the transient enhanced diffusion of shallow molecular-beam-epitaxy grown marker layers of Sb and B due to deep MeV Si"+ ion implants at very high doses (#approx#10"1"6cm"-"2). We expect the near-surface region of these implants to be vacancy rich, and we observe transient enhanced diffusion of Sb (the classic vacancy diffuser). The large enhancements imply a significant vacancy supersaturation (#approx#700 at 740 degree C). Double implantation of the high-dose MeV Si followed by a shallow (40 keV) Si implant and annealing produces a greatly reduced number of #left brace#311#right brace# defects compared to a 40 keV implant into virgin Si, again consistent with a vacancy-rich region in the near-surface region of an MeV implant. However, the shallow B marker layers also show transient enhanced diffusion for the same MeV implant under similar annealing conditions, implying that an interstitial ...

481

Transient enhanced diffusion in ion-implanted silicon  

Energy Technology Data Exchange (ETDEWEB)

We discuss the transient-enhanced diffusion of Sb, As, P, In, Ga, and B in ion-implanted Si, where the near-surface region has been amorphized by the dopant or by a self-implantation process. With Sb, a large transient diffusion enhancement is observed proportional to dopant concentration. For Sb, As, P, and In, the enhancement follows the relative interstitialcy diffusion coefficient. We believe this behavior is caused by stable implantation-induced point defects present in the amorphous surface layer, which decay during thermal processing to release high concentrations of self-interstitials. This process occurs in competition with the solid phase epitaxial (SPE) growth process, and for high dopant concentrations can occur in the amorphous phase ahead of the crystallization front. We believe this may be the origin of the dopant redistribution which can occur during SPE growth, which sets the upper limit to the dopant ...

1987-03-01

482

Intensification of harmonic spontaneous radiation with a novel undulator  

International Nuclear Information System (INIS)

We have calculated the on-axis spectrum of spontaneous radiation emitted by an electron moving along a planar undulator that has a magnetic profile along the axis that approximates a square wave. (This could be obtained in practice by driving a ferromagnetic undulator into saturation by excessivecurrent in the windings.) We find considerable enhancement of the harmonic radiation spectrum. We compare the harmonic power emitted by an electron moving through an undulator having a sine-wave field profile with the radiation emitted from an undulator having a square-wave profile; the latter is approximated by the first three Fourier components of the undulator magnetic field profile along the axial direction. Examples are computed for 40MeV electrons taking K1 is greatly enhanced for the approximate square-wave magnetic profile: the ratio of the power emitted at f=5 by the square-wave undulator to that of the sine-wave undulator is about 15 (whereas ...

1999-07-01

483

Intensification of Harmonic Spontaneous Radiation with a Novel Undulator  

Science.gov (United States)

We have calculated the on-axis spectrum of spontaneous radiation emitted by an electron moving along a planar undulator that has a magnetic profile along the axis that approximates a square wave. (This could be obtained in practice by driving a ferromagnetic undulator into saturation by excessive current in the windings.) We find considerable enhancement of the harmonic radiation spectrum. We compare the harmonic power emitted by an electron moving through an undulator having a sine-wave field profile with the radiation emitted from an undulator having a square-wave profile; the latter is approximated by the first three Fourier components of the undulator magnetic field profile along the axial direction. Examples are computed for 40MeV electrons taking K < 1, for spontaneous radiation emitted along the axis of the system. The emission at harmonics f > 1 is greatly enhanced for the approximate square-wave magnetic profile: the ratio of the ...

1998-11-01

484

Influence of hormones and medium components on expression of dipyranocoumarins in cell suspension cultures of Calophyllum inophyllum L.  

British Library Electronic Table of Contents (United Kingdom)

Cell suspension cultures were initiated separately from leaf and nodal/internodal calluses for the study of influence of hormones and medium components on biomass growth and expression of dipyranocoumarins. Highest 6.2 times biomass was enhanced in suspension cultures of nodal/internodal callus supplemented with threefold total sulphate. Picloram 8.28mM along with BAP 8.88mM enhanced 295.05 times inophyllum A in suspension cultures of leaf callus whereas IBA 14.70mM along with BAP 4.44mM in suspension cultures of leaf callus enhanced 1065 times inophyllum B. IBA 4.90mM alone in suspension cultures of nodal/internodal callus enhanced maximum 616 times inophyllum C. Only IBA 9.80mM in suspension cultures of leaf callus enhanced 23.22 times inophyllum P. Variation in nitrate and sulphate had ...

2009-01-01

485

Experimental investigations on the characteristics of melting processes of stearic acid in an annulus and its thermal conductivity enhancement by fins  

Energy Technology Data Exchange (ETDEWEB)

An experimental rig was set up to study the performance of a thermal storage unit using stearic acid as the heat storage medium. The unit mainly consists of an electrical heating rod and an outer tube, and the space between is an annulus that is filled with stearic acid. The thermal performance of the unit is measured, and the heat transfer characteristics of the melting processes of stearic acid are studied under different heat flux conditions to determine the influence of heat flux on the melting processes. A new type of fin is designed and fixed to the electrical heating rod to enhance the thermal response of the stearic acid. The experimental results show that the fin can improve the heat transfer of the melting process of the thermal storage unit greatly. The equivalent thermal conductivity of the PCM can be augmented by a factor up to 3. The analysis of the experimental results shows that the enhancement mechanism of the fin is attributed ...

2005-04-01

486

Experimental investigations on the characteristics of melting processes of stearic acid in an annulus and its thermal conductivity enhancement by fins  

Energy Technology Data Exchange (ETDEWEB)

An experimental rig was set up to study the performance of a thermal storage unit using stearic acid as the heat storage medium. The unit mainly consists of an electrical heating rod and an outer tube, and the space between is an annulus that is filled with stearic acid. The thermal performance of the unit is measured, and the heat transfer characteristics of the melting processes of stearic acid are studied under different heat flux conditions to determine the influence of heat flux on the melting processes. A new type of fin is designed and fixed to the electrical heating rod to enhance the thermal response of the stearic acid. The experimental results show that the fin can improve the heat transfer of the melting process of the thermal storage unit greatly. The equivalent thermal conductivity of the PCM can be augmented by a factor up to 3. The analysis of the experimental results shows that the enhancement mechanism of the fin is attributed ...

2005-04-01

487

Enhanced cadmium cytotoxicity in A549 cells with reduced glutathione levels is due to neither enhanced cadmium accumulation nor reduced metallothionein synthesis  

International Nuclear Information System (INIS)

Glutathione (GSH) depletion sensitizes human lung carcinoma (A549-T27) cells to the cytotoxic effects of Cd++. The effects of GSH depletion on Cd++ accumulation and Cd++-induced metallothionein (MT) content were investigated to determine the possible role of these Cd++ responses in the sensitization process. Cellular GSH was depleted to 20% to 25% of control levels with buthionine sulfoximine (BSO), or diethyl maleate (DEM), respectively. Neither treatment significantly affected Cd++-induced accumulation of exogenous 35s-cysteine into intracellular MT in a dose-dependent fashion. The results indicate that neither enhanced Cd++ accumulation nor reduced MT synthesis plays a primary role in affecting enhanced Cd++ cytotoxicity in A549 cells with reduced GSH levels. Although BSO inhibition of GSH synthesis enhanced MT synthesis, it sensitized the cells to Cd++, which suggests an additive effect of GSH and MT in cadmium ...

488

Enhanced CT in the diagnosis of acute appendicitis to evaluate the severity of disease. Comparison of CT findings and histological diagnosis  

Energy Technology Data Exchange (ETDEWEB)

To assess the potential of CT in evaluating the histological severity of acute appendicitis in comparison with surgical and pathological findings. The CT images of 75 patients with surgically proven appendicitis, including 10 cases of catarrhal, 34 of phlegmonous, and 31 of gangrenous appendicitis, were retrospectively analyzed for the following five CT findings: hazy periappendiceal densities, enlarged appendix, increased enhancement of the appendiceal wall, increased enhancement of the periappendiceal intestinal wall, and deficiency of the appendiceal wall. By comparing all the CT findings and the pathological severity of appendicitis (catarrhal, phlegmonous, and gangrenous), the prevalence of the five CT findings was calculated for each pathological category. Abnormal CT findings were noted in only one case of catarrhal appendicitis. Increased enhancement of the appendiceal wall was observed in all 29 cases of ...

2001-08-01

489

Design considerations for simple gas dosers in surface science applications  

International Nuclear Information System (INIS)

The flux distributions and enhancement factors for various gas doser designs typically used in surface science applications and chemisorption studies have been calculated and compared. The following conclusions, which will aid the experimentalist in the choice of doser design, can be made. (1) The enhancement factor expected for a given doser can easily be derived from Fig. 2. (2) The optimum doser design is a multichannel array with a radius slightly larger than that of the sample, and a distance from the sample < 10% of the sample diameter. (Complications of this design are discussed.) (3) Because of space requirements, the sample--doser distance must sometime be > or =40% of the sample diameter, in which cases it is better to use a cosine emitter. A good, very simple doser design is described that consists of a small cosine emitter with a sample--doser distance of 1/2 the sample diameter. This provides an ...

490

Boron-enhanced diffusion of boron from ultralow-energy ion implantation  

Energy Technology Data Exchange (ETDEWEB)

We have investigated the diffusion enhancement mechanism of boron-enhanced diffusion (BED), wherein boron diffusivity is enhanced four to five times over the equilibrium diffusivity at 1050&hthinsp;{degree}C in the proximity of a silicon layer containing a high boron concentration. It is demonstrated that BED is driven by excess interstitials injected from the high boron concentration layer during annealing. For evaporated layers, BED is observed above a threshold boron concentration between 1{percent} and 10{percent}, though it appears to be closer to 1{percent} for B-implanted layers. For sub-keV B implants above the threshold, BED dominates over the contribution from transient-enhanced diffusion to junction depth. For 0.5 keV B, this threshold implantation dose lies between 3{times}10{sup 14} and 1{times}10{sup 15} cm{sup {minus}2}. It is proposed that the excess interstitials responsible for BED ...

1999-04-01

491

Boron-enhanced diffusion of boron from ultralow-energy ion implantation  

International Nuclear Information System (INIS)

We have investigated the diffusion enhancement mechanism of boron-enhanced diffusion (BED), wherein boron diffusivity is enhanced four to five times over the equilibrium diffusivity at 1050 ampersand hthinsp;degree C in the proximity of a silicon layer containing a high boron concentration. It is demonstrated that BED is driven by excess interstitials injected from the high boron concentration layer during annealing. For evaporated layers, BED is observed above a threshold boron concentration between 1% and 10%, though it appears to be closer to 1% for B-implanted layers. For sub-keV B implants above the threshold, BED dominates over the contribution from transient-enhanced diffusion to junction depth. For 0.5 keV B, this threshold implantation dose lies between 3x10"1"4 and 1x10"1"5 cm"-"2. It is proposed that the excess interstitials responsible for BED are produced during the formation of a silicon ...

1999-04-01

492

Atomic force microscopy and surface-enhanced Raman scattering detection of DNA based on DNA-nanoparticle complexes  

Energy Technology Data Exchange (ETDEWEB)

We report a simple method for the label-free detection of double-stranded DNA using surface-enhanced Raman scattering (SERS). We prepared cetyltrimethylammonium bromide (CTAB)-capped silver nanoparticles and a DNA-nanoparticle complex by adding silver nanoparticles to {lambda}-DNA solutions. In the present study, the utilization of CTAB-capped silver nanoparticles facilitates the electrostatic interaction between DNA molecules and silver nanoparticles; at the same time, the introduction of DNA avoids adding aggregating agent for the formation of nanoparticle aggregates to obtain large enhancement of DNA, because the DNA acts as both the probe molecules and aggregating agent of Ag nanoparticles. Atomic force microscopy (AFM) studies show that the morphology of DNA-Ag nanoparticle complexes seems to be determined by the concentrations of the DNA and the nanoparticles. Surface-enhanced Raman scattering (SERS) studies show that ...

2009-03-25

493

A transient enhanced diffusion model of lattice restoration during rapid thermal annealing (RTA)  

International Nuclear Information System (INIS)

A transient-enhanced diffusion has been observed during the furnace or rapid thermal annealing of As-implanted Si. The relations of the enhanced diffusion to residual defects and lattice restoration have been studied in detail. The As concentration profiles and residual defects are measured. It is found from the data that the lattice has been restored when the implanted sample is annealed at 1150 deg C (or 1050 deg C) for 1s. The defect density decreases rapidly with increase of annealing time (from 1 to 12s). The enhanced diffusion coefficient maximum appears in the annealing time ranging from 1 to 5s. Allmost a 'complete' annealing of displacemet damage is obtained and the diffusion coefficient is less than that in above-mentioned conditions when the implanted samples are annealed at 1150 deg C in the time ranging from 12 to 20s. the mechanism of lattice restoration and enhanced diffusion in annealing ...

494

Transforming growth factor-b induces nerve growth factor expression in pancreatic stellate cells by activation of the ALK-5 pathway  

British Library Electronic Table of Contents (United Kingdom)

Nerve growth factor (NGF), a survival factor for neurons enforces pain by sensitizing nociceptors. Also in the pancreas, NGF was associated with pain and it can stimulate the proliferation of pancreatic cancer cells. Hepatic stellate cells (HSC) respond to NGF with apoptosis. Transforming growth factor (TGF)-b, one of the strongest pro-fibrogenic activators of pancreatic stellate cells (PSC) induced NGF and its two receptors in an immortalized human cell line (ihPSC) and primary rat PSC (prPSC) as determined by RT-PCR, western blot, and immunofluorescence. In contrast to HSC, PSC expressed both NGF receptors, although p75NTR expression was weak in prPSC. In contrast to ihPSC TGF-b activated both Smad signaling cascades in prPSC. NGF secretion was diminished by the activin-like kinase (ALK)...

2009-01-01

495

Tissue perfusion measurements: multiple-exposure laser speckle analysis generates laser Doppler-like spectra  

Science.gov (United States)

Variations in skin perfusion are easily detected by laser speckle contrast maps, but a robust interpretation of the information has been lacking. We show that multiple-exposure laser speckle methods produce the same spectral information as laser Doppler methods when applied to targets with embedded moving scatterers. This enables laser speckle measurements to be interpreted more quantitatively. We do this by using computer simulation of speckle data, and by experimental measurements on Brownian motion and skin perfusion using a laser Doppler system and a multiple-exposure laser speckle system. The power spectral density measurements of the light fluctuations derived using both techniques are exactly equivalent. Dermal perfusion can therefore be measured by laser Doppler or laser speckle contrast methods. In particular, multiexposure laser speckle can be rapidly processed to generate a full-field map of the perfusion index proportional to the ...

2010-03-01

496

PET/MRI hybrid imaging: devices and initial results  

International Nuclear Information System (INIS)

The combination of functional and morphological imaging technologies such as positron emission tomography (PET) and X-ray computed tomography (CT) has shown its value in the clinical and preclinical field. However, CT provides only very limited soft-tissue contrast and exposes the examined patient or laboratory animal to a high X-ray radiation dose. In comparison to CT, magnetic resonance tomography (MRI) provides excellent soft-tissue contrast and allows for nuclear magnetic resonance spectroscopy (NMRS) or functional MRI (fMRI). Thus, the combination of PET and MRI has been pursued for several years. First approaches have succeeded using conventional photo multiplier tube (PMT) technology together with light fibers to transfer scintillation light away from the high magnetic field. Latest PET/MRI developments use solid-state light detectors that can be operated even at high magnetic fields. Initial pilot studies with prototype animal PET/MRI ...

2008-06-01

497

Grating-based X-ray phase imaging using multiline X-ray source  

International Nuclear Information System (INIS)

Differential phase-contrast X-ray imaging has been performed in a Talbot-Lau configuration, where a multiline X-ray source was used instead of a combination of a hard-X-ray multiple slit and a normal focus X-ray generator. When the multiple slit is used, a high aspect ratio structure is needed and slit width should be below 10 ?m for its function. The fabrication and use of such a multislit can be omitted using the presented configuration. The multiline X-ray source was developed by making grooves on a tungsten rotating anode, which was irradiated by an electron beam to generate X-rays. An array of 10?m line sources with a pitch of 30?m was formed and combined with a 4.5 ?m pitch phase grating and a 5.3 ?m pitch amplitude grating to generate differential phase contrast. With a total exposure time of 40 s, a differential phase image depicting cartilages was obtained. (author)

2009-07-01

498

Functional MRI of the visual cortex and visual testing in patients with previous optic neuritis.  

DEFF Research Database (Denmark)

The volume of cortical activation as detected by functional magnetic resonance imaging (fMRI) in the visual cortex has previously been shown to be reduced following optic neuritis (ON). In order to understand the cause of this change, we studied the cortical activation, both the size of the activated area and the signal change following ON, and compared the results with results of neuroophthalmological testing. We studied nine patients with previous acute ON and 10 healthy persons served as controls using fMRI with visual stimulation. In addition to a reduced activated volume, patients showed a reduced blood oxygenation level dependent (BOLD) signal increase and a greater asymmetry in the visual cortex, compared with controls. The volume of visual cortical activation was significantly correlated to the result of the contrast sensitivity test. The BOLD signal increase correlated significantly to both the results of the contrast sensitivity test ...

2002-01-01

499

Assessment of the effects of pixel loss on image quality in direct digital radiography  

Energy Technology Data Exchange (ETDEWEB)

Modern digital radiographic 'flat panel' detectors can exhibit a progressive form of image degradation arising from non-functioning pixels. The effect of these 'dead pixels' on the quantitative image quality measures of modulation transfer function (MTF), noise power spectrum (NPS) and detective quantum efficiency (DQE) is investigated by a simulated degradation of images obtained from an Hologic EPEX system. The effects on the semi-quantitive measures obtained from contrast threshold test objects and resolution gratings are also investigated. Results suggest that the contrast-detail tests often employed in quality assurance measures are not sufficient to reveal the presence of dead pixels until well beyond the recommended replacement point for the flat panel detector. However, measurements of spatial resolution using a line pairs phantom were found to be more sensitive to pixel loss. Measurement of the MTF, ...

2004-03-21

500

Assessment of the effects of pixel loss on image quality in direct digital radiography  

International Nuclear Information System (INIS)

Modern digital radiographic 'flat panel' detectors can exhibit a progressive form of image degradation arising from non-functioning pixels. The effect of these 'dead pixels' on the quantitative image quality measures of modulation transfer function (MTF), noise power spectrum (NPS) and detective quantum efficiency (DQE) is investigated by a simulated degradation of images obtained from an Hologic EPEX system. The effects on the semi-quantitive measures obtained from contrast threshold test objects and resolution gratings are also investigated. Results suggest that the contrast-detail tests often employed in quality assurance measures are not sufficient to reveal the presence of dead pixels until well beyond the recommended replacement point for the flat panel detector. However, measurements of spatial resolution using a line pairs phantom were found to be more sensitive to pixel loss. Measurement of the MTF, NPS and DQE can reveal small changes ...

2004-03-21