familial evans syndrome: Topics by WorldWideScience.org

Congenital anal anomalies in two families with the Opitz G syndrome.

... elevated blood sugar levels, but not full-blown diabetes. What are the keys to preventing the disease? ... been well studied, in a study called The Diabetes Prevention Program, in several thousand people with this ...

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Crassulacean Acid Metabolism and Epiphytism Linked to Adaptive Radiations in the Orchidaceae1[OA

Five children from two families presented to a regional neonatal surgical unit between 1959 and 1984 with congenital anal anomalies and other malformations resulting from an autosomal dominant inherited...Full Text Available

1987-11-01

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A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells

Species of the large family Orchidaceae display a spectacular array of adaptations and rapid speciations that are linked to several innovative features, including specialized pollination syndromes,...Full Text Available

2009-04-01

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Detection of the first gross CDC73 germline deletion in an HPT-JT syndrome family

Frontotemporal lobar degeneration is a progressive neurodegenerative syndrome that is the second most common cause of early-onset dementia. Mutations in the progranulin gene are a major cause of familial...Full Text Available

2011-03-15

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British Library Electronic Table of Contents (United Kingdom)

Abstract Hereditary primary hyperparathyroidism (HPT) may develop as a solitary endocrinopathy (FIHP) or as part of multiple endocrine neoplasia Type 1, multiple endocrine neoplasia Type 2A, or hereditary HPT-jaw tumor syndrome. Inactivating germline mutations of the tumor suppressor gene CDC73 account for 14 and 50% of all FIHP and HPT-JT patients, respectively, and have also been found in almost 20% of apparently sporadic parathyroid carcinoma patients. Although more than 60 independent germline mutations have been described, to date no rearrangement affecting the CDC73 locus has been identified. By means of multiplex-PCR we found a large germline deletion affecting the whole gene in a two-generation HPT-JT family. Subsequently array-CGH and specific PCR analysis determined that the muta...

2011-01-01

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Familial unilateral deafness and delayed endolymphatic hydrops

British Library Electronic Table of Contents (United Kingdom)

Delayed endolymphatic hydrops (DEH) is a unique disorder characterized by fluctuating otologic symptoms in the setting of preexisting unilateral deafness. The symptoms include aural fullness, fluctuating hearing, and/or episodes of vertigo similar to those observed in Meniere disease and may occur ipsilateral or contralateral to the previously deafened ear. In most reported cases, the unilateral deafness has been a profound sensorineural hearing loss with a sudden onset that has been variously attributed to bacterial or viral labyrinthitis, acoustic or cranial trauma, otosclerosis, and congenital CMV infection. Familial occurrence of the syndrome has not previously been reported in the literature. In this report, we describe two possible familial instances of delayed DEH. These patients ra...

2007-01-01

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Traumatic and Non-traumatic Fibromyalgia Syndrome: Impact Assessment on the Life Quality of Women

British Library Electronic Table of Contents (United Kingdom)

Objective To investigate the impact on life quality of women with traumatic and non-traumatic origin fibromyalgia syndrome [FMS]. Method Women affected with FMS were selected and divided into two groups: those with traumatic origin FMS [Group 1] and those with non-traumatic origin FMS [Group 2]. A standard question form was used for the research, as well as the fibromyalgia impact questionnaire [FIQ] for evaluation of life quality. Results Seventy-two patients, 34 for Group 1 and 38 for Group 2 were analyzed. The main triggering symptoms were divorce [23.5 percent of cases] and death in the family [23.5 percent of cases]. In addition to diffuse pain, the main symptoms presented were poor sleep quality, weariness, and paresthesia, with no difference between the groups; migraine had a greate...

2011-01-01

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Identification of mutations leading to the Lesch-Nyhan syndrome by automated direct DNA sequencing of in vitro amplified cDNA

Clinical and metabolic characteristics of polycystic ovary syndrome without polycystic ovary: a pilot study on Chinese women

The Lesch-Nyhan (LN) syndrome is a severe X chromosome-linked disease that results from a deficiency of the purine salvage enzyme hypoxanthine phosphoribosyltransferase (HPRT). The mutations leading to the disease are heterogeneous and frequently arise as de novo events. The authors have identified nucleotide alterations in 15 independently arising HPRT-deficiency cases by direct DNA sequencing of in vitro amplified HPRT cDNA. They also demonstrate that the direct DNA sequence analysis can be automated, further simplifying the detection of new mutations at this locus. The mutations include DNA base substitutions, small DNA deletions, a single DNA base insertion, and errors in RNA splicing. The application of these procedures allows DNA diagnosis and carrier identification by the direct detection of the mutant alleles within individual families affected by LN.

1989-03-01

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British Library Electronic Table of Contents (United Kingdom)

Objective To demonstrate clinical features of a patient subgroup presenting with polycystic ovary syndrome (PCOS) without polycystic ovary morphology. Design Retrospective study. Setting Hospital-based IVF center. Patient(s) In the present study, 876 PCOS patients were selected from women who visited the Reproductive Medicine Center at Shandong Provincial Hospital, Shandong University, between September 2004 and October 2006. Women with PCOS were divided into two groups based on ultrasound image: group A, PCOS patients with classic polycystic ovary (n = 800); group B, PCOS patients without polycystic ovary morphology (n = 76). The following available data were analyzed in the large cohort of women: body height, weight, waistline, hip circumference, hirsutism scores, family history, serum s...

2008-01-01

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Linkage analysis in familial Angelman syndrome

Child labour: ground realities of Indian labour laws

Familial Angelman syndrome (AS) can result from mutations in chromosome 15q11q13 that, when transmitted from father to child, result in no phenotypic abnormality but, when transmitted from mother to child, cause AS. These mutations therefore behave neither as dominant nor as recessive mutations but, rather, show an imprinted mode of inheritance. The authors have analyzed two sibling pairs with AS and a larger family with four AS offspring of three sisters with several recently described microsatellite polymorphisms in the AS region. AS siblings inherited the same maternal alleles at the GABRB3 and GABRA5 loci, and the unaffected siblings of AS individuals inherited the other maternal alleles at these loci. In one of the AS sibling pairs, analysis of a recombination event indicates that the mutation responsible for AS is distal to locus D15S63. This result is consistent with a previously described imprinted submicroscopic ...

1993-07-01

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British Library Electronic Table of Contents (United Kingdom)

There has been growing international consensus on issues related to child labour - evident in various declarations, platforms, conventions, programmes of action etc. Child labour is the economic exploitation of children, or performance of any work that is likely to be hazardous or to interfere with the child's health or physical, mental, spiritual, moral or social development. Poverty is the principal cause of child labour. Mostly the children work to support their families and also for their own survival. Paradoxically, however, child labour further aggravates the poverty syndrome as it usually deprives the children of education and opportunity to acquire skills for developing earning potentials. Other causes of child labour include family indebtedness, the lack or poor quality of schooli...

2011-01-01

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IDEAS: Working Papers, Georgetown University, Department of Economics

Second primary cancers of the breast: incidence and risk factors.

...] gueconwpa~05-05-05 How is Macro News Transmitted to Exchange Rates? (December 2003) by Martin D. D. Evans(Georgetown University and NBER) and Richard K. Lyons(U.C. Berkeley and NBER, Haas School of Business) [Downloadable!] gueconwpa~05-05-04 A New Micro Model of Exchange Rate Dynamics (March 2004) by Martin D. D. Evans(Georgetown University and ...

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Role of vasopressin in regulation of renal kinin excretion in Long-Evans and diabetes insipidus rats.

Between 1946 and 1976 over 9,000 women with breast cancer were seen within one year of diagnosis at the A. Maxwell Evans Clinic (AMEC) in Vancouver, British Columbia. By 1978, 275 had a subsequent diagnosis...Full Text Available

1984-01-01

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Variation in response to dexamethasone of a patient with Cushing's syndrome.

To study the relationship between vasopressin and the renal kallikrein-kinin system we measured the rate of excretion of kinins into the urine of anesthetized rats during conditions of increased and...Full Text Available

1984-03-01

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Neuroleptic malignant syndrome.

A patient with Cushing's syndrome due to a nonresectable chromophobe adenoma underwent external irradiation of the hypothalamic-pituitary area. The signs of Cushing's syndrome ameliorated subsequently...Full Text Available

1976-11-06

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AEC syndrome - Genetics Home Reference

Neuroleptic malignant syndrome is a life-threatening reaction of neuroleptic medication. The estimated incidence rate of neuroleptic malignant syndrome is between 1% and 1.5% of patients treated with...Full Text Available

1992-11-01

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Scientist who linked chronic fatigue syndrome to XMRV is sacked.

What genes are related to AEC syndrome? AEC syndrome is caused by mutations in the TP63 gene. This gene provides instructions for making a protein known as p63, which plays an...

2011-10-15

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Prenatal Diagnosis of Recurrent Trisomy 18 Syndrome

PMID:21990156

2011-10-11

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Hypothesis for induction and propagation of chemical sensitivity based on biopsy studies.

Full Text Available

2003-02-01

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An encounter with the syndrome of multiple chemical sensitivities: Reflections of a pharmacologist

The reactive airways dysfunction syndrome (RADS), the reactive upper airways dysfunction syndrome (RUDS), the sick building syndrome (SBS), and the multiple chemical sensitivity syndrome (MCS) are overlapping...Full Text Available

1997-03-01

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Asperger Syndrome - What it Feels Like (3)

No abstract available.

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Syzygy Theorems via comparison of order ideals on a hypersurface

Jake, who has been diagnosed with Asperger syndrome, explains that he has developed a number of ritualistic habits.

2009-04-14

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British Library Electronic Table of Contents (United Kingdom)

We introduce a weak order ideal property that suffices for establishing the Evans-Griffith Syzygy Theorem. We study this weak order ideal property in settings that allow for comparison between homological algebra over a local ring R versus a hypersurface ring R =R/(x^n). Consequently we solve some relevant cases of the Evans-Griffith syzygy conjecture over local rings of unramified mixed characteristic p, with the case of syzygies of prime ideals of Cohen-Macaulay local rings of unramified mixed characteristic being noted. We reduce the remaining considerations to modules annihilated by p^s, s>0, that have finite projective dimension over a hypersurface ring.

2012-01-01

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Work and family--allies or enemies? what happens when business professionals confront life choices

Genetic and physical mapping of the Chediak-Higashi syndrome on chromosome 1q42-43

Work and family--allies or enemies?

2000-01-01

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Aarskog-Scott syndrome: Clinical update and report of nine novel mutations of the FGD1 gene

The Chediak-Higashi syndrome (CHS) is a severe autosomal recessive condition, features of which are partial oculocutaneous albinism, increased susceptibility to infections, deficient natural killer cell activity, and the presence of large intracytoplasmic granulations in various cell types. Similar genetic disorders have been described in other species, including the beige mouse. On the basis of the hypothesis that the murine chromosome 13 region containing the beige locus was homologous to human chromosome 1, we have mapped the CHS locus to a 5-cM interval in chromosome segment 1q42.1-q42.2. The highest LOD score was obtained with the marker D1S235 (Z{sub max} = 5.38; {theta} = 0). Haplotype analysis enabled us to establish D1S2680 and D1S163, respectively, as the telomeric and the centromeric flanking markers. Multipoint linkage analysis confirms the localization of the CHS locus in this interval. Three YAC clones were found to cover the entire region in a contig ...

1996-09-01

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DEFF Research Database (Denmark)

Mutations in the FGD1 gene have been shown to cause Aarskog-Scott syndrome (AAS), or facio-digito-genital dysplasia (OMIM#305400), an X-linked disorder characterized by distinctive genital and skeletal developmental abnormalities with a broad spectrum of clinical phenotypes. To date, 20 distinct mutations have been reported, but little phenotypic data are available on patients with molecularly confirmed AAS. In the present study, we report on our experience of screening for mutations in the FGD1 gene in a cohort of 60 European patients with a clinically suspected diagnosis of AAS. We identified nine novel mutations in 11 patients (detection rate of 18.33%), including three missense mutations (p.R402Q; p.S558W; p.K748E), four truncating mutations (p.Y530X; p.R656X; c.806delC; c.1620delC), one in-frame deletion (c.2020_2022delGAG) and the first reported splice site mutation (c.1935+3A>C). A recurrent mutation (p.R656X) was detected in three independent ...

2010-01-01

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Religious groups have too much freedom to discriminate | Evan Harris | Comment is free | guardian.co.uk

Role of ocular involvement in the prediction of visual development and clinical prognosis in Aicardi syndrome.

... Wanting to help a charity is commendable but the main focus of generosity should be the people in front of you, not your choice of spiritual overlord - especially so if the group is being funded with money from taxpayers. Recommend? (44) Report abuse | Link ...

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Metabolic syndrome in subjects with type-2 diabetes mellitus.

AIMS/BACKGROUND: This study was undertaken to document visual function and acuity in patients with Aicardi syndrome, and to determine whether there is any relation between ocular features of the syndrome...Full Text Available

1996-09-01

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The nystagmus blockage syndrome.

BACKGROUND: Each component of metabolic syndrome (MS) conveys increased cardiovascular disease risk, but as a combination they become much more powerful. Vigorous early management of the syndrome may...Full Text Available

2004-06-01

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Syndromic management of urethral discharge in Ghanaian pharmacies

A previously unrecognized form of nystagmus associated with esotropia was described in the German literature by Adelstein and Cüppers in 1966 as the nystagmus blockage syndrome. Even though...Full Text Available

1976-01-01

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Prospective Study of Motor, Sensory, Psychological and Autonomic Functions in Patients with Irritable Bowel Syndrome

Objectives: To evaluate the training of pharmacists in Accra, Ghana, in the syndromic management of STIs. Methods: We randomly selected 50 pharmacy outlets that had...Full Text Available

2000-12-01

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Postpartum spontaneous colonic perforation due to antiphospholipid syndrome

Background/AimTo assess pathophysiology in irritable bowel syndrome (IBS).Methods122 IBS patients...Full Text Available

2008-07-01

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Female urethral syndrome. A female prostatitis?

The antiphospholipid syndrome (APS) is a multi-systemic disease being characterized by the presence of antiphospholipid antibodies that involves both arterial and venous systems resulting in arterial...Full Text Available

2009-01-28

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Executive dysfunction in frontotemporal dementia and corticobasal syndrome

The cause of the female urethral syndrome has previously been obscure, as it has been associated by definition with a lack of objective findings but a plethora of subjective complaints of retropubic...Full Text Available

1996-05-01

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Medical Student Outcomes after Family-Centered Bedside Rounds

Objective:To determine the pattern of executive dysfunction in frontotemporal dementia (FTD) and corticobasal syndrome (CBS) and to determine the brain areas associated with executive...Full Text Available

2009-02-03

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Survey of Families with Children

ObjectiveFamily-centered bedside rounds (FCBR) are recommended to improve trainee education, patient outcomes, and family satisfaction. However, bedside teaching...Full Text Available

2011-09-01

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The Clinical Efficacy of GOCA Scoring System in Patients with Acute Respiratory Distress Syndrome

heterogeneity bias Static models: Other models:

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Partial retraction. Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome.

Full Text Available

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Jarcho-Levin syndrome--a report of an autopsy case with cytogenetic analysis.

PMID:21998366

2011-10-14

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Delineation of the ADULT syndrome phenotype due to arginine 298 mutations of the p63 gene

Full Text Available

1993-12-01

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DEFF Research Database (Denmark)

Udgivelsesdato: 2006/8

2006-01-01

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Disorders of brain development and phakomatosis

Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis

Full text: Disorders of brain development and phakomatosis are resulting from disturbed embryonic-foetal development One third of all major embryological anomalies involve CNS, and over 2000 different anomalies have been described. Anomalies of the brain often cause foetal and neonatal death, and mental and physical retardation in pediatric group. The majority of disorders of brain development and phakomatosis are idiopathic, and most of them are not hereditary or familial. Ultrasonography plays the important role in screening foetal and neonatal brain, but after closure of fontanels it is difficult to find the acoustic window. CT has limited contrast resolution, and disadvantage exposing infant to ionizing radiation. It is helpful to demonstrate the presence of calcifications. MR imaging has proved to be a diagnostic tool of major importance in children with disorders of brain development and phakomatosis. The excellent grey/white matter differentiation and ...

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Werner syndrome protein interacts functionally with translesion DNA polymerases

Wiskott-Aldrich syndrome protein (WASp) is essential for optimal T cell activation. Patients with WAS exhibit both immunodeficiency and a marked susceptibility to systemic autoimmunity. We investigated...Full Text Available

2007-02-01

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The management of children with chronic fatigue syndrome-like illness in primary care: a cross-sectional study

Werner syndrome (WS) is characterized by premature onset of age-associated disorders and predisposition to cancer. The WS protein, WRN, encodes 3′ → 5′ DNA helicase and 3′...Full Text Available

2007-06-19

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The endogenous hydrogen sulfide producing enzyme cystathionine-? synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome

BackgroundMost studies on children with chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) have been undertaken in tertiary care and little is known about their management...Full Text Available

2006-01-01

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The Serotonin Transporter Polymorphism rs25531 Is Associated with Irritable Bowel Syndrome

BackgroundThe pathogenesis of visceral hypersensitivity, a characteristic pathophysiological feature of irritable bowel syndrome (IBS), remains elusive. Recent studies suggest a...Full Text Available

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Targeting the Pentose Phosphate Pathway in Syndrome X-related Cardiovascular Complications

Irritable bowel syndrome is a frequent gastrointestinal disorder of unknown etiology. The serotonin transporter regulates the intensity and duration of serotonin signaling in the gut and is,...Full Text Available

2009-12-01

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TSH Isoforms: About a Case of Hypothyroidism in a Down's Syndrome Young Adult

Syndrome X is a combination or co-occurrence of several known cardiovascular risk factors (including central obesity, dyslipidemias, fatty liver disease, hyperinsulinemia, insulin resistance,...Full Text Available

2010-05-01

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Stem Cell Therapies Benefit Alport Syndrome

Background. For unknown reasons, the prevalence of thyroid autoimmune disorders is higher in patients with Down's syndrome than in the general population. The present case strongly...Full Text Available

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Socioeconomic Status and Depressive Syndrome: The Role of Inter- and Intra-generational Mobility, Government Assistance, and Work Environment*

Patients with Alport syndrome progressively lose renal function as a result of defective type IV collagen in their glomerular basement membrane. In mice lacking the α3 chain of type IV collagen...Full Text Available

2009-11-01

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Psychopathological features of irritable bowel syndrome patients with and without functional dyspepsia: a cross sectional study

This paper assesses the hypothesis that depressive syndrome is associated with socioeconomic status, using longitudinal data from the Baltimore Epidemiologic Catchment Area Followup. Socioeconomic...Full Text Available

2001-09-01

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Peptide Nanoparticles as Novel Immunogens: Design and Analysis of a Prototypic Severe Acute Respiratory Syndrome Vaccine

BackgroundIrritable bowel syndrome (IBS) and functional dyspepsia (FD) show considerable overlap and are both associated with psychiatric comorbidity. The present study aimed to...Full Text Available

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Pelvic floor disorders and quality of life in women with self-reported irritable bowel syndrome

Severe acute respiratory syndrome (SARS) is an infectious disease caused by a novel coronavirus that cost nearly 800 lives. While there have been no recent outbreaks of the disease, the threat...Full Text Available

2009-01-01

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Pathophysiological, Genetic and Gene Expression Features of a Novel Rodent Model of the Cardio-Metabolic Syndrome

SummaryBackgroundQuality of life among women with irritable bowel syndrome may be affected by pelvic floor disorders.AimFull Text Available

2010-02-01

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Ocular manifestations of branchio-oculo-facial syndrome: Report of a novel mutation and review of the literature

BackgroundComplex etiology and pathogenesis of pathophysiological components of the cardio-metabolic syndrome have been demonstrated in humans and animal models.Methodology/Principal...Full Text Available

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Multicenter Case-Control Study on Restless Legs Syndrome in Multiple Sclerosis: the REMS Study

PurposeTo report unusual ocular manifestations of branchio-oculo-facial syndrome (BOFS) caused by a novel mutation in activating enhancer binding protein 2 alpha (TFAP2A).MethodsFull...Full Text Available

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Investigation of a syndrome of sudden death, splenomegaly, and small intestinal hemorrhage in farmed deer

Study objectives:To verify the existence of a symptomatic form of restless legs syndrome (RLS) secondary to multiple sclerosis (MS) and to identify possible associated risk factors.Design:Prospective,...Full Text Available

2008-07-01

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Infection dynamics and clinical manifestations following experimental inoculation of gilts at 90 days of gestation with a low dose of porcine reproductive and respiratory syndrome virus

AbstractA newly recognized syndrome, characterized by sudden death of farmed deer that are in good to excellent nutritional condition, with lesions of small intestinal mucosal hemorrhage...Full Text Available

2005-08-01

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Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction

Understanding the dynamics of porcine reproductive and respiratory syndrome virus (PRRSV) vertical transmission is important to enhance the accuracy of monitoring protocols for endemically infected...Full Text Available

2009-10-01

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Ichthyosis follicularis, alopecia, and photophobia (IFAP) syndrome

We sought to determine the prevalence of metabolic syndrome (MS) in patients with acute myocardial infarction and its effect on clinical outcomes. Employing data from the Korea Acute Myocardial Infarction...Full Text Available

2010-10-01

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Functional interaction between the Werner Syndrome protein and DNA polymerase ?

The IFAP syndrome is a rare X-linked genetic disorder reported in nearly 40 patients. It is characterized by the triad of Ichthyosis Follicularis, Alopecia, and Photophobia from birth. Other features...Full Text Available

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Foraminal stenosis complicating retained broken epidural needle tip -A case report-

Werner Syndrome (WS) is an inherited disease characterized by premature onset of aging, increased cancer incidence, and genomic instability. The WS gene encodes a 1,432-amino acid polypeptide (WRN)...Full Text Available

2000-04-25

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Fetofetal transfusion syndrome: do the neonatal criteria apply in utero?

Lumbar epidural anesthesia is useful in a variety of chronic benign pain syndromes, including lumbar radiculopathy, low back pain syndrome, spinal stenosis, and vertebral compression fractures. Given...Full Text Available

2010-12-01

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Factors associated with irritable bowel syndrome symptoms in hemodialysis patients

Thirteen fetuses (five twin, one triplet) were compromised by fetofetal transfusion syndrome in six pregnancies, five in the mid trimester, and one in the third trimester. This diagnosis, which was...Full Text Available

1990-07-01

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Explicit risk in acute coronary syndrome management

AIM: To investigate clinical characteristics associated with the presence of irritable bowel syndrome (IBS) symptoms in hemodialysis (HD) patients.METHODS: This was a cross-sectional study. A...Full Text Available

2011-04-21

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Endoscopic Discectomy for the Cauda Equina Syndrome During Third Trimester of Pregnancy

At least implicitly, most clinical decisions represent an integration of disease and treatment-based risk assessments. Often, as is the case with acute coronary syndrome (ACS), these decisions need...Full Text Available

2009-06-01

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Effect of widespread restrictions on the use of hospital services during an outbreak of severe acute respiratory syndrome

Low back pain is common during pregnancy. However, the prevalence of symtomatic lumbar disc herniation is rare, and cauda equina syndrome due to disc herniation during pregnancy is even rarer. We report...Full Text Available

2007-11-01

69

Diarrheal Illness Detected Through Syndromic Surveillance After a Massive Power Outage: New York City, August 2003

BackgroundRestrictions on the nonurgent use of hospital services were imposed in March 2003 to control an outbreak of severe acute respiratory syndrome (SARS) in Toronto, Ont. We...Full Text Available

2007-06-19

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Detecting Retroviral Sequences in Chronic Fatigue Syndrome

Objectives. We investigated increases in diarrheal illness detected through syndromic surveillance after a power outage in New York City on August 14, 2003.Methods....Full Text Available

2006-03-01

71

Comparison of prasugrel and clopidogrel in patients with acute coronary syndrome undergoing percutaneous coronary intervention

XMRV or xenotropic murine leukemia virus-related retrovirus, a recently discovered retrovirus, has been linked to both prostate cancer and chronic fatigue syndrome (CFS). Recently, the teams of Drs....Full Text Available

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Comparative analysis of differentially expressed genes in normal and white spot syndrome virus infected Penaeus monodon

Antiplatelet agents are the cornerstone of treatment for patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). Clopidogrel, when added to aspirin, has demonstrated...Full Text Available

2009-01-01

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Citalopram is not Effective Therapy for Non-Depressed Patients with Irritable Bowel Syndrome

BackgroundWhite spot syndrome (WSS) is a viral disease that affects most of the commercially important shrimps and causes serious economic losses to the shrimp farming industry worldwide....Full Text Available

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Catecholamine and Cortisol Levels during Sleep in Women with Irritable Bowel Syndrome

Background & AimsData are conflicting on the benefit of selective serotonin reuptake inhibitors (SSRIs) for patients with irritable bowel syndrome (IBS);...Full Text Available

2010-01-01

75

Carpal Tunnel Syndrome and Peripheral Polyneuropathy in Patients with End Stage Kidney Disease

Evidence suggests that patients with irritable bowel syndrome (IBS) are hyper-responsive to environmental, physical, and visceral stimuli. IBS patients also frequently report poor sleep quality....Full Text Available

2009-11-01

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A rare case of neuroleptic malignant syndrome presenting with serious hyperthermia treated with a non-invasive cooling device: a case report

This study was designed to identify the causes of the development of carpal tunnel syndrome (CTS) associated with end stage kidney disease (ESKD). A total of 112 patients with ESKD, 64 on hemodialysis...Full Text Available

2011-09-01

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Use of information sources by family physicians: a literature survey.

IntroductionA rare side effect of antipsychotic medication is neuroleptic malignant syndrome, mainly characterized by hyperthermia, altered mental state, haemodynamic dysregulation,...Full Text Available

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Life Stress, Maternal Optimism, and Adolescent Competence in Single Mother, African American Families

Analysis of the use of information sources by family physicians is important for both practical and theoretical reasons. First, analysis of the ways in which family physicians handle information may...Full Text Available

1995-01-01

79

Health and function of participants in the Long Life Family Study: A comparison with other cohorts

Although research demonstrates many negative family outcomes associated with single-parent households, little is known about processes that lead to positive outcomes for these families. Using...Full Text Available

2010-08-01

80

Genome-Wide Identification and Evolutionary Analysis of the Animal Specific ETS Transcription Factor Family

Individuals from families recruited for the Long Life Family Study (LLFS) (n= 4559) were examined and compared to individuals from other cohorts to determine whether the recruitment targeting longevity...Full Text Available

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Evaluating Patients with Chronic Pain and their Families

The ETS proteins are a family of transcription factors (TFs) that regulate a variety of biological processes. We made genome-wide analyses to explore the classification of the ETS gene family. We identified...Full Text Available

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After-Hours Information Given by Telephone by Family Physicians in Ontario

Inclusion of family members in the assessment of patients with chronic pain can improve outcomes. Family functioning can be assessed in four basic areas: boundaries, power, communication, and intimacy....Full Text Available

1991-02-01

83

A study on multi-cultural family wives adapting to Korean cuisine and dietary patterns

This study describes instructions for after-hours care offered by family physicians' offices when patients telephone the practice. Randomly selected (n=1,680) Ontario family physicians and general practitioners...Full Text Available

2009-11-01

84

Towbin, Kenneth E. Curriculum Vitae

With the increase in multi-cultural families, Korea is seeing a rapid increase in immigrated housewives, who are closely related to food culture. However, studies for the diet of multi-cultural families,...Full Text Available

2010-10-01

85

On Syndrome Decoding for Source Coding Based on Convolutional and Turbo Codes

... Attention Deficit Hyperactivity Disorder. In: Kurlan, R. (ed.) The Handbook of Tourette's Syndrome and Related Tic and Behavioral Disorders. ...

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Computerized tomography of the adrenal glands in the Cushing Syndrome propaedeutic

In source coding, either with or without side information at the decoder, the ultimate performance can be achieved by means of random binning. Structured binning into cosets of performing channel codes has been successfully employed in practical applications. In this letter it is formally shown that various convolutional- and turbo-syndrome decoding algorithms proposed in literature lead in fact to the same estimate. An equivalent implementation is also delineated by directly tackling syndrome decoding as a maximum a posteriori probability problem and solving it by means of iterative message-passing. This solution takes advantage of the exact same structures and algorithms used by the conventional channel decoder for the code according to which the syndrome is formed.

2009-01-01

87

Blood plasma concentration of somatomedin-C in patients with Cushing Syndrome

Portuguese (Mar 1983). Brazil Furlanetto, RP Abucham Filho, J. Albertotti,

1982-10-24

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"Hang Up Your Pocketbook" -- an easy intervention for the granny syndrome: grandparents as a risk factor in unintentional pediatric exposures to pharmaceuticals.

Portuguese 1984. p. 127. Brazil Giannella Neto, D. Santomauro, ATMG

1984-10-27

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Stability and Change in Family Structure and Maternal Health Trajectories

PMID:16912339

2006-07-01

90

Coping Strategies of Family Members of Hospitalized Psychiatric Patients

Recent increases in births to unmarried parents, and the instability surrounding these relationships, have raised concerns about the possible health effects associated with changes in family...Full Text Available

2008-04-01

91

Automated radon radiometers of RRA family

This exploratory research paper investigated the coping strategies of families of hospitalized psychiatric patients and identified their positive and negative coping strategies. In this paper, the coping...Full Text Available

2011-01-01

92

Zollinger-Ellison syndrome: Presentation, response to therapy, and outcome

Two automated radiometers of RRA family designed for radon concentration measurements are presented. Principal performance specifications and promising applications of the radiometers are presented.

1999-08-01

93

British Library Electronic Table of Contents (United Kingdom)

Background: Recent series describing the clinical presentation, response to therapy, and long-term outcome of Zollinger-Ellison syndrome are limited. Aims: To assess the clinical characteristics and long-term outcome of patients with Zollinger-Ellison syndrome. Methods: Over a 20-year period, patients with Zollinger-Ellison syndrome were enrolled in a prospective trial evaluating the efficacy of lansoprazole. Following dose stabilization, patients were followed on a 6-monthly basis with interval history, physical examination, endoscopy with gastric biopsies, gastric acid analysis and laboratory studies. Results: 72 patients (mean age 54+/-12 years, % male 58%, % Caucasian 69%) were prospectively enrolled. The clinical presentation was stereotypical for Zollinger-Ellison syndrome. Symptoms ...

2011-01-01

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Formation of blisters in tantalum by 30 MeV alpha particle bombardment

Formation of blisters in tantalum by 30 MeV alpha particle bombardment

The phenomenon of radiation blistering by helium ion bombardment has been the subject of extensive studies in recent years because of its technological importance in thermonuclear fusion devices and reactors. However, the mechanism of radiation blistering is still not well understood. There are two different models of blister formation: the gas-pressure model and the lateral stress model. The former model is, however, supported by many experimental observations, the prominent one is that of Evans and Eyre who observed blisters appearing on the front and rear surfaces of a thin wedge-shaped molybdenum foil irradiated by helium ions. Their experiment also indicates that the thickness of the irradiated specimen could be important in affecting the characteristics of blisters. With this in view, we have studied the development of blisters in thin foils of tantalum by 30 MeV ..cap alpha..-particle bombardment.

1984-08-01

95

A calf for all seasons? The potential of stable isotope analysis to investigate prehistoric husbandry practices

The phenomenon of radiation blistering by helium ion bombardment has been the subject of extensive studies in recent years because of its technological importance in thermonuclear fusion devices and reactors. However, the mechanism of radiation blistering is still not well understood. There are two different models of blister formation: the gas-pressure model and the lateral stress model. The former model is, however, supported by many experimental observations, the prominent one is that of Evans and Eyre who observed blisters appearing on the front and rear surfaces of a thin wedge-shaped molybdenum foil irradiated by helium ions. Their experiment also indicates that the thickness of the irradiated specimen could be important in affecting the characteristics of blisters. With this in view, we have studied the development of blisters in thin foils of tantalum by 30 MeV #alpha#-particle bombardment. (orig.).

96

British Library Electronic Table of Contents (United Kingdom)

The Early Bronze Age barrows at Irthlingborough and Gayhurst in central England are notable for the large number of cattle (Bos taurus) remains associated with their human Beaker burials. Previous work using strontium isotope analysis has indicated that most of the cattle analysed, and one aurochs (Bos primigenius), were of local origin [Towers, J., Montgomery, J., Evans, J., Jay, M., Parker Pearson, M., 2010. An investigation of the origins of cattle and aurochs deposited in the Early Bronze Age barrows at Gayhurst and Irthlingborough. Journal of Archaeological Science 37, 508-515.]. In this study, stable isotope analysis of enamel and bone was carried out to investigate whether the mature cattle had experienced similar husbandry practices, climate and environment. Bulk carbon, nitrogen a...

2011-01-01

97

The Effect of Self-esteem, Academic Achievement and Family Functioning of Adolescents on Hope

September 2000 Number 146

Full Text Available

2001-01-01

98

Police Family Life Education Project (FLEP) Implementations, September 11, 1999, October 2, 1999, April 29, 2000 and June 24, 2000. Follow-Up Surveys of Families Who Attended Each of the Classes-Final Report.

Improved Education Some suggest that the full range of groups that deal with families and pets could benefit

99

If I Had - A Family History of Muscular Dystrophy

The major purpose of the Police Family Life Education Project (FLEP) is 'to develop and deliver a program that will provide police recruits and their immediate family members with stress management education that focuses on the role and responsibilities o...

2001-01-01

100

Diabetic Vitrectomy Surgery

... parent groups that are wonderful and lots of networking and a lot of interactions between the foundations, ...

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101

An In-Hospital Family Member Cardiopulmonary Resuscitation (CPR) Education Program

... anything wrong; it could be summertime. So just vigilance with yearly exams. If you have a family ...

102

A new family of Hydroidea, together with a description of the structure of a new species of Plumularia, by W. Baldwin ...

Cardiac Arrest; Coronary Disease; Cardiovascular Risk Factors

2010-12-13

103

An efficient higher order family of root finders

Language: English ...

104

British Library Electronic Table of Contents (United Kingdom)

A one parameter family of iterative methods for the simultaneous approximation of simple complex zeros of a polynomial, based on a cubically convergent Hansen-Patricks family, is studied. We show that the convergence of the basic family of the fourth order can be increased to five and six using Newtons and Halleys corrections, respectively. Since these corrections use the already calculated values, the computational efficiency of the accelerated methods is significantly increased. Further acceleration is achieved by applying the Gauss-Seidel approach (single-step mode). One of the most important problems in solving nonlinear equations, the construction of initial conditions which provide both the guaranteed and fast convergence, is considered for the proposed accelerated family. These cond...

2008-01-01

105

Thai Family Health Routines: scale development and psychometric testing.

Incidental discovery of asplenia syndrome, with situs inversus and a normal heart by radionuclide biliary imaging. A case report

The aims of the study were to develop and test the psychometric properties of the Thai Family Health Routines (TFHR) scale, a 70-item self-report questionnaire used to measure the health of Thai families through their routine behaviors in daily life. Development of the TFHR was based on the structural domains of Denham's Family Health Model. The TFHR scale was initially composed of 85 items and tested on 1,040 families living in the central region of Thailand. The confirmatory factor analysis, with an acceptable factor structure model, yielded 70 items aligned with six factors: self-care, safety and prevention, mental health behavior, family care, family caregiving, and illness care routines. The preliminary psychometric properties demonstrated that the TFHR scale had satisfactory internal consistency, criterion validity, and construct validity. The test results ...

2009-05-01

106

Hypersersensitivity and Kounis syndrome due to a viper bite

/sup 99m/Tc biliary imaging was performed on a 34-year-old woman who was being investigated for suspected cholelithiasis. A left-sided liver was detected. On subsequent radionuclide imaging, partial visceral situs inversus and asplenia were demonstrated. Extensive roentgenographic investigation, ECG, echocardiogram, and laparotomy confirmed the radionuclide findings. Asplenia syndrome may exist without cardiovascular abnormalities and thus be undiscovered. Radionuclide imaging is important in the diagnosis of this syndrome.

107

British Library Electronic Table of Contents (United Kingdom)

A 60-year-old male was bitten by a venomous snake (Vipera ammodytes) and gradually developed signs of an allergic reaction including generalized itching, generalized rash, and chest discomfort. This was followed by severe retrosternal pain with electrocardiographic evidence of an inferior myocardial ischemia progressing to acute myocardial infarction. Cardiac enzymes and troponin, serum tryptase, and histamine were elevated. Coronary arteriography showed normal coronary arteries. This is a characteristic type I variant of Kounis syndrome, which is the concurrence of acute coronary syndromes with conditions associated with mast cell activation including allergic or hypersensitivity reactions as well as anaphylactic or anaphylactoid reactions. This is the first report to show that viper bite...

2006-01-01

108

Aicardi syndrome: a case report and radiologic findings; Sindrome de Aicardi: relato de caso e achados radiologicos

Terminal phalangeal accessory ossification center of the thumb: an additional radiographic finding in Larsen syndrome

The authors report the findings of Aicardi syndrome, a disease of unknown etiology composed of multiple spasms, chorioretinal lacunae and agenesis of the corpus callosum. They present a case of Aicardi syndrome with characteristic clinical presentation and magnetic resonance imaging findings. The disease, despite being considered rare, has characteristic imaging findings. Over the past years magnetic resonance imaging has improved its ability in demonstrating other findings besides agenesis of the corpus callosum, making the radiologist's role very important in the diagnostic suspicion of this disease. (author)

2008-07-01

109

Standard of mineralocorticoid secretion in the Cushing Syndrome: evidences of inhibition of the aldosterone path synthesis in the glomerulus zone

Larsen syndrome is an autosomal-dominant disorder characterized by multiple joint dislocations, vertebral anomalies and dysmorphic facies. Both autosomal-dominant and autosomal-recessive forms of the disorder have been proposed. Individuals with autosomal-dominant Larsen syndrome have characteristic ''cylindrical-shape'' thumbs caused by broad, shortened phalanges. Autosomal-dominant Larsen syndrome results from heterozygosity for mutations in filamin B, a cytoskeletal protein involved in multicellular processes. We report here a patient with a duplicated or accessory distal thumb phalanx and multiple large joint dislocations who was shown to be heterozygous for a filamin B mutation predicting the amino acid substitution G1691S. This adds a new radiographic finding, duplicated or accessory distal phalanx, to the radiographic abnormalities seen in this rare dominant disorder. (orig.)

2006-09-01

110

Sensibility and specification of the rapid test of depression with dexamethasone (1 mg,oral) in Cushing Syndrome diagnosis

Portuguese 1984. p. 146. Brazil Czepielewski, MA Kater, CE Biglieri, EG Escola

1984-10-27

111

Nutcracker Phenomenon and Nutcracker Syndrome

Portuguese 1984. p. 147. Brazil Accursio, WJ Vieira, JGH Kater, CE Chacra,

1984-10-27

112

Neuroradiologic and Neurophysiologic Findings of Neuralgic Amyotrophy

Nutcracker phenomenon refers to compression of the left renal vein, most commonly between the aorta and the superior mesenteric artery, with impaired blood outflow often accompanied by distention...Full Text Available

2010-06-01

113

Hypersensitivity pneumonitis.

ObjectiveNeuralgic amyotrophy (NA) is a distinct clinical syndrome that is characterized by the acute onset of shoulder and arm pain, weakness, and sensory loss. The purpose of this...Full Text Available

2010-11-01

114

Functional and Oncologic Outcomes of Partial Adrenalectomy for Pheochromocytoma in Patients With von Hippel-Lindau Syndrome After at Least 5 Years of Followup

Although the cause and development of most inflammatory and fibrotic interstitial lung diseases are unknown, both the antigenic stimuli and the immunopathogenic mechanisms that produce the syndrome...Full Text Available

1993-11-01

115

British Library Electronic Table of Contents (United Kingdom)

PurposeAlthough the safety and feasibility of partial adrenalectomy in patients with von Hippel-Lindau syndrome have been established, long-term outcomes have not been examined. In this study we evaluate the recurrence and functional outcomes in a von Hippel-Lindau syndrome cohort treated for pheochromocytoma with partial adrenalectomy with a followup of at least 5 years. Materials and MethodsWe reviewed the records of patients with von Hippel-Lindau syndrome treated with partial adrenalectomy for pheochromocytoma at the National Cancer Institute. Demographic, germline mutation status, surgical indication, oncologic and functional outcome data were collected. Local recurrence was defined as radiographic evidence of recurrent tumor on the ipsilateral side of partial adrenalectomy. Patients ...

2010-01-01

116

Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model

Efficacy and adverse effects of intravenous lignocaine therapy in fibromyalgia syndrome

BackgroundMutations that disrupt the conversion of prelamin A to mature lamin A cause the rare genetic disorder Hutchinson-Gilford progeria syndrome and a group of laminopathies....Full Text Available

117

Depression, coronary artery disease, type 2 diabetes, metabolic syndrome and quality of life in Taiwanese adults from a cardiovascular department of a major hospital in Southern Taiwan

BackgroundTo investigate the effects of intravenous lignocaine infusions (IV lignocaine) in fibromyalgia.MethodsProspective study...Full Text Available

118

British Library Electronic Table of Contents (United Kingdom)

Aims.- To examine the relationships between depression, coronary artery disease, type 2 diabetes, metabolic syndrome and quality of life in Taiwanese adults from a cardiovascular department of a major hospital in Taiwan. Background.- Research suggests associations between depression, metabolic syndrome and quality of life. Despite this fact, few studies have investigated these relationships among Taiwanese. Design.- A cross-sectional descriptive correlational design was used to conduct this study. Methods.- A convenience sample of 140 adults participated in the study. Data were analysed with descriptive statistics, Pearson-s correlations, hierarchical regression and t-tests. Results.- Almost a half of the subjects (465%) had metabolic syndrome. The most common combination of metabolic synd...

2011-01-01

119

Computational mouse atlases and their application to automatic assessment of craniofacial dysmorphology caused by the Crouzon mutation Fgfr2C342Y

British Library Electronic Table of Contents (United Kingdom)

Abstract Crouzon syndrome is characterized by premature fusion of sutures and synchondroses. Recently, the first mouse model of the syndrome was generated, having the mutation Cys342Tyr in Fgfr2c, equivalent to the most common human Crouzon/Pfeiffer syndrome mutation. In this study, a set of micro-computed tomography (CT) scannings of the skulls of wild-type mice and Crouzon mice were analysed with respect to the dysmorphology caused by Crouzon syndrome. A computational craniofacial atlas was built automatically from the set of wild-type mouse micro-CT volumes using (1) affine and (2) non-rigid image registration. Subsequently, the atlas was deformed to match each subject from the two groups of mice. The accuracy of these registrations was measured by a comparison of manually placed landma...

2007-01-01

120

Chronic Disability Syndrome

Bone scintiscanning with [Tc-99m] MDP in patients with McCune-Albright syndrome; Cintilografia ossea com MDP [Tc-99m] em pacientes com sindrome de McCune-Albright

Prolonged disability is best understood as an illness that exists independently of the initiating disease. The disabled individual goes through predictable stages of disability before resolution occurs....Full Text Available

1991-09-01

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121

Adder bite: an uncommon cause of compartment syndrome in northern hemisphere

No abstract prepared.

2000-07-01

122

A cost-utility analysis of open and endoscopic carpal tunnel release

Snakebite envenomation is an uncommon condition in the northern hemisphere, but requires high vigilance with regard to both the systemic effects of the venom and the locoregional impact on the soft...Full Text Available

123

A child with hyperferritinemia: Case report

BACKGROUNDOpen carpal tunnel release (OCTR) is the standard procedure for the surgical treatment of carpal tunnel syndrome. With the advent of minimally invasive surgery, endoscopic...Full Text Available

2006-01-01

124

A case of Meigs syndrome mimicking metastatic breast carcinoma

Hereditary hyperferritinemia cataract syndrome (HHCS) is a rare condition caused by mutations in the gene coding for the light chain of ferritin; it does not lead to iron overload, but it is associated...Full Text Available

125

The epidemiology of Graves' disease: Evidence of a genetic and an environmental contribution

BackgroundAdnexal masses are not uncommon in patients with breast cancer. Breast cancer and ovarian malignancies are known to be associated. In patients with breast cancer and co-existing...Full Text Available

126

British Library Electronic Table of Contents (United Kingdom)

Previous family and twin studies have indicated that Graves' disease has a heritable component. Family studies have also shown that some autoimmune disease cluster in families and genetic studies have been able to show shared susceptibility genes. In the present nation-wide study we describe familial risk for Graves' disease among parents and offspring, singleton siblings, twins and spouses with regard to age of onset, gender and number and type of affected family members. Additionally familial association of Graves' disease with any of 33 other autoimmune and related conditions was analyzed. The Swedish Multigeneration Register on 0-75-year-old subjects was linked to the Hospital Discharge Register from years 1987-2007. Standardized incidence ratios (SIRs) were calculated for individuals ...

2010-01-01

127

Youth-Family, Youth-School Relationship, and Depression

Variants within the yeast Ty sequence family encode a class of structurally conserved proteins.

This study sought to examine the association between adolescents’ relationship with family and school and depressive symptoms across ethnic/racial groups (White, Black, Hispanic, and...Full Text Available

2010-04-01

128

Treatment planning for children with attention-deficit/hyperactivity disorder: treatment utilization and family preferences

The Ty transposable elements of Saccharomyces cerevisiae form a heterogeneous family within which two broad structural classes (I and II) exist. The two classes differ by two large substitutions and...Full Text Available

1985-06-11

129

The ovalbumin gene family: complete sequence and structure of the Y gene.

BackgroundAttention-deficit/hyperactivity disorder (ADHD) is a common condition that often results in child and family functional impairments. Although there are evidence-based treatment...Full Text Available

130

The Friedreich Ataxia Critical Region Spans A 150-kb Interval on Chromosome 9q13

The "ovalbumin Y" gene, one of three which constitute the ovalbumin gene family in chicken has been completely sequenced. The exact location of exons can be derived from the comparison with the ovalbumin...Full Text Available

1982-07-24

131

Support groups for dementia caregivers - Predictors for utilisation and expected quality from a family caregiver's point of view: A questionnaire survey PART I*

By analysis of crossovers in key recombinant families and by homozygosity analysis of inbred families, the Friedreich ataxia (FRDA) locus was localized in a 300-kb interval between the X104 gene and...Full Text Available

1995-11-01

132

SLC25A4 - solute carrier family 25 (mitochondrial carrier; adenine...

BackgroundSupport groups have proved to be effective in reducing the burden on family caregivers of dementia patients. Nevertheless, little is known about the factors that influence...Full Text Available

133

Rare mutations predisposing to familial adenomatous polyposis in Greek FAP patients

The official name of this gene is "solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4." SLC25A4 is the gene's official symbol. The...

2011-08-13

134

Mutations in TPRN Cause a Progressive Form of Autosomal-Recessive Nonsyndromic Hearing Loss

BackgroundFamilial Adenomatous Polyposis (FAP) is caused by germline mutations in the APC (Adenomatous Polyposis Coli) gene. The vast majority of APC mutations...Full Text Available

135

Molecular Identification and Expression Analysis of Filaggrin-2, a Member of the S100 Fused-Type Protein Family

We performed genome-wide homozygosity mapping in a large consanguineous family from Morocco and mapped the autosomal-recessive nonsyndromic hearing loss (ARNSHL) in this family to the DFNB79...Full Text Available

2010-03-12

136

INFLUENCE OF PERCEIVED SECONDARY STIGMA AND FAMILY ON THE RESPONSE TO HIV INFECTION AMONG INJECTION DRUG USERS IN VIETNAM

Genes of the S100 fused-type protein (SFTP) family are clustered within the epidermal differentiation complex and encode essential components that maintain epithelial homeostasis and barrier functions....Full Text Available

137

Heterogeneous mutations in the human lipoprotein lipase gene in patients with familial lipoprotein lipase deficiency.

The full impact of secondary stigma (stigma directed at family) on an HIV-positive individual is unknown. This qualitative research explores perceptions of secondary stigma in the Vietnamese...Full Text Available

2010-12-01

138

Food meanings in HIV and AIDS caregiving trajectories: Ritual, optimism and anguish among caregivers in Lesotho

The DNA sequences were determined for the lipoprotein lipase (LPL) gene from five unrelated Japanese patients with familial LPL deficiency. The results demonstrated that all five patients are homozygotes...Full Text Available

1991-12-01

139

Familial occurrence of unilateral giant breasts in Nigeria: a possible new genetic entity.

The article describes the caregiving responsibility to provide food for chronically ill family members and the meanings attached to food and eating when ill created stress for family caregivers. The...Full Text Available

2011-02-05

140

Diabetes mellitus patients' family caregivers' subjective quality of life.

Four cases of unilateral giant breasts from two unrelated families are described. Three of the patients were managed surgically. It is speculated from a review of available published reports that this...Full Text Available

1984-04-01

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141

Cytogenetic analysis of three sea catfish species (Teleostei, Siluriformes, Ariidae) with the first report of Ag-NOR in this fish family

OBJECTIVES: To assess the subjective quality of life (QOL) of family caregivers of Sudanese type-1 and type-2 diabetic outpatients, using the WHO 26-item QOL instrument, compared with a general population...Full Text Available

2006-05-01

142

Cultural and Contextual Influences on Parenting in Mexican American Families

Despite their ecological and economical importance, fishes of the family Ariidae are still genetically and cytogenetically poorly studied. Among the 133 known species of ariids, only eight have been...Full Text Available

2010-04-01

143

Coevolution of activating and inhibitory receptors within mammalian carcinoembryonic antigen families

Family stress theory can explain associations between contextual stressors and parenting. However, the theory has not been tested among Mexican Americans or expanded to include cultural-contextual...Full Text Available

2009-02-01

144

Breaking the 1000-gene barrier for Mimivirus using ultra-deep genome and transcriptome sequencing

BackgroundMost rapidly evolving gene families are involved in immune responses and reproduction, two biological functions which have been assigned to the carcinoembryonic antigen...Full Text Available

145

Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100.

BackgroundMimivirus, a giant dsDNA virus infecting Acanthamoeba, is the prototype of the mimiviridae family, the latest addition to the family of the nucleocytoplasmic...Full Text Available

146

Anticipation in familial lattice corneal dystrophy type I with R124C mutation in the TGFBI (BIGH3) gene

Familial defective apolipoprotein (apo) B-100 is a genetic disease that leads to hypercholesterolemia and to an increased serum concentration of low density lipoproteins that bind defectively to the...Full Text Available

1989-01-01

147

Analysis of the bmp Gene Family in Borrelia burgdorferi Sensu Lato

PurposeTo report the clinical, ophthalmic, and genetic characteristics for lattice corneal dystrophy type I (LCDI) in a Chilean family.MethodsSix...Full Text Available

148

An Arabidopsis thaliana methyltransferase capable of methylating farnesoic acid?

BmpA, BmpB, BmpC, and BmpD are homologous Borrelia burgdorferi lipoproteins of unknown functions, encoded by the bmp genes of paralogous chromosomal gene family 36....Full Text Available

2000-04-01

149

A new VCAN/versican splice acceptor site mutation in a French Wagner family associated with vascular and inflammatory ocular features

We previously reported the identification of a new family of plant methyltransferases (MTs), named the SABATH family, that use S-adenosyl-l-methionine (SAM) to methylate...Full Text Available

2006-04-15

150

The Seosan County Family Planning/Maternal & Child Health Service Research Project, Korea -Project Design and Findings of the Baseline Survey-

PurposeTo detail the highly variable ocular phenotypes of a French family affected with an autosomal dominantly inherited vitreoretinopathy and to identify the disease gene.MethodsSixteen...Full Text Available

151

Family Life Cycle and Deforestation in Amazonia: Combining Remotely Sensed Information with Primary Data

Full Text Available

1983-10-01

152

Association between HLA-G genotype and risk of pre-eclampsia: a case-control study using family triads

This paper examines the relationships between the socio-demographic characteristics of small

2003-01-01

153

DEFF Research Database (Denmark)

Udgivelsesdato: 2004-Apr

2004-01-01

154

The Werner syndrome helicase protein is required for cell proliferation, immortalization, and tumorigenesis in Scaffold Attachment Factor B1 deficient mice

PET and MR imaging in a neuro-Behcet syndrome

Werner syndrome (WS) is a rare disorder characterized by the premature onset of several pathologies associated with aging. The gene responsible for WS codes for a RecQ-type DNA helicase and is believed...Full Text Available

155

Klippel-feil syndrome with situs inversus. A rare association

Positron emission tomography (PET) and magnetic resonance imaging (MRI) studies were performed on a case of neuro-Behcet's syndrome. In accordance with the clinical signs, FDG PET (using /sup 18/F-labeled 2-F-2'-desoxyglucose) revealed disseminated storage defects in the cerebrum and cerebellum. Focal regions of enhanced signal intensity were demonstrated in the parietal white matter of the cerebrum in T2-weighted images and in the brain stem by MRI. (orig.).

1989-11-01

156

IL-6 promotes nonthyroidal illness syndrome by blocking thyroxine activation while promoting thyroid hormone inactivation in human cells

Klippel-Feil Syndrome (KFS) is a congenital anomaly characterized by a defect in the formation or segmentation of the cervical vertebrae. The clinical triad consists of short neck, low posterior hairline and limited neck movement. Multiple congenital anomalies have been associated with this disease. This is a case of KFS in a young girl along with situs inversus, which is an extremely rare association. Various systemic associations occurring in this multi-system disorder are also discussed. (author)

2008-04-01

157

Clinical Characteristics and Outcomes of Patients with Acute Coronary Syndrome and Prior Coronary Artery Bypass Grafting in a Large Middle Eastern Cohort

Nonthyroidal illness syndrome (NTIS) is a state of low serum 3,5,3′ triiodothyronine (T₃) that occurs in chronically ill patients; the degree of reduction in T₃ is associated...Full Text Available

2011-05-02

158

Chronic fatigue syndrome, XMRV and blood safety

Background:Acute Coronary Syndrome (ACS) can occur in patients with prior coronary artery bypass grafting (CABG). In the Gulf Registry of acute coronary events (Gulf RACE), we identified...Full Text Available

159

British Library Electronic Table of Contents (United Kingdom)

In the past few months, there has been public discussion relating to a new perspective on blood safety and specifically upon measures to prevent or discourage donation by individuals with a diagnosis of myalgic encephalopathy-chronic fatigue syndrome. This reflects an intriguing interplay between science, public health and public concern and illustrates some of the difficulties of making decisions in the face of uncertainty and inadequate information.

2011-01-01

160

Category III Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Insights from The National Institutes of Health Chronic Prostatitis Collaborative Research Network Studies

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) remains an enigmatic medical condition. Creation of the (NIH) Chronic Prostatitis Collaborative Research Network (CPCRN) funded by...Full Text Available

2008-07-01

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161

Universal Similarity

Cummins Turbo Technologies launches new family of turbochargers for smaller diesel engines at IAA Hannover - Public Service

We survey a new area of parameter-free similarity distance measures useful in data-mining, pattern recognition, learning and automatic semantics extraction. Given a family of distances on a set of objects, a distance is universal up to a certain precision for that family if it minorizes every distance in the family between every two objects in the set, up to the stated precision (we do not require the universal distance to be an element of the family). We consider similarity distances for two types of objects: literal objects that as such contain all of their meaning, like genomes or books, and names for objects. meaning, like genomes or books, and names for objects. The latter may have literal embodyments like the first type, but may also be abstract like ``red'' or ``christianity.'' For the first type we consider a family of computable distance measures corresponding to parameters ...

2005-01-01

162

Hood River Fish Habitat Project; Confederated Tribes of the Warm Springs Reservation of Oregon, Annual Report 2001-2002.

...Cummins Turbo Technologies launches new family of turbochargers for smaller diesel engines at IAA Hannover, public service, publicservice.co.uk Cummins Turbo Technologies ...launches new family of turbochargers for smaller diesel engines at IAA Hannover Cummins Turbo Technologies launches new family of turbochargers for smaller diesel engines at IAA ...Facebook Delicious Cummins Turbo Technologies launches new family of turbochargers for smaller diesel engines at IAA Hannover Cummins Turbo Technologies, a global engineering leader ...turbocharger technology, launched a new range of diesel turbochargers specifically designed for diesel engines from 2 -5 litre capacity today at IAA Hannover. Cummins ...

163

Experimental studies on reconstruction of peripheral arteries by high voltage cathode ray irradiated allografts

This report summarizes the project implementation and monitoring of all habitat activities that occurred over Fiscal Year 2002 (FY 02). Some of the objectives in the corresponding statement of work for this contract were not completed within FY 02. A description of the progress during FY 02 and reasoning for deviation from the original tasks and timeline are given. OBJECTIVE 1--Provide coordination of all activities, administrative oversight and assist in project implementation and monitoring activities. Administration oversight and coordination of the habitat statement of work, budget, subcontracts and personnel was provided. OBJECTIVE 2--Develop, coordinate, and implement the Hood River Fish Habitat Protection, Restoration, and Monitoring Plan. The Hood River Fish Habitat Protection, Restoration, and Monitoring Plan was completed in 2000 (Coccoli et al., 2000). This document is utilized for many purposes including: drafting the Watershed Action Plan, ranking projects for funding, and ...

2003-11-01

164

Evaluation of a convenient method of assessing rodent visual function in safety pharmacology studies: Effects of sodium iodate on visual acuity and retinal morphology in albino and pigmented rats and mice

The use of cathode ray irradiated arterial allografts on the reconstruction of small peripheral arteries is described. The fate of irradiated arterial allografts implanted subcutaneously in rats was compared histologically with that of allografts which were fresh, frozen or stored in 70% alcohol. Follow-up studies were made of 10 dogs in which irradiated arterial allografts had been implanted in the femoral artery to be evaluated; long term patency by arteriography, gross and histologic changes of the implanted allografts, and the luminal surface of the implanted allografts by scanning electron microscopic studies. For the purpose of antigenic studies, extracts of canine arteries which had been irradiated, frozen or stored in 70% alcohol, were prepared and tested by the following immunological methods: precipitation, Ouchterlony gel diffusion, and passive cutaneous anaphylaxis. From the results obtained in these experiments, it was concluded that, compared with fresh or frozen grafts ...

1976-01-01

165

British Library Electronic Table of Contents (United Kingdom)

Introduction: We have evaluated the ability of a semi-automated, optomotor reflex method to assess drug-induced visual dysfunction, in albino and pigmented rats and mice. Methods: Male Han Wistar (HW) and Long Evans (LE) rats and mice (CD-1 and C57BL/6) were tested in a chamber formed by 4 computer monitors displaying a rotating vertical grating, to elicit head-tracking movements. The highest visible grating frequency was taken as the threshold of visual acuity, in cycles per degree (c/d). Animals received an intravenous infusion of either sodium iodate (50mg/kg) or 0.9% w/v NaCl (aq). They were tested 2h later, then re-tested daily for a further 3days. The time course of the effect was assessed in HW rats over a 6-week period, including electron microscopy, and immunohistochemical analysi...

2011-01-01

166

CERN Academic Training Programme 2008/2009

CERN Multimedia

LECTURE SERIES 8, 9, 10 11 & 12 June 2009 11:00-12:00 - Main Auditorium, Bldg. 500 Scenarios and Technological Challenges for a LHC Luminosity Upgrade: Introduction to the LHC Upgrade Program and Summary of Physics Motivations After a general introduction to the motivations for a LHC upgrade, the lectures will discuss the beam dynamics and technological challenges of the increase of the LHC luminosity, and the possible scenarios. Items such as a stronger final focus with larger aperture magnets, crab cavities, electron cloud issues, beam-beam interaction, machine protection and collimation will be discussed.Monday 8 June 2009 Introduction to the LHC upgrade program - L. Evans Summary of Physics Motivations - M. Mangano Tuesday 9 June 2009 The Dectector Upgrade and the Requirements on the Upgrade Scenarios - M. Nessi Wednesday 10 June 2009 Scenarios for the LHC Luminosity Upgrade - F. Zimmermann Thursday 11 June 2009 Main Accelerator Science Challenges: Magnet ...

2009-01-01

167

Reversal of Premature Ovarian Failure in a Patient with Sj?gren Syndrome Using an Elimination Diet Protocol

British Library Electronic Table of Contents (United Kingdom)

Abstract Background: Premature ovarian failure is diagnosed with a picture of amenorrhea, elevated follicle-stimulating hormone (FSH), and age under 40 years. Twenty percent (20%) of patients with premature ovarian failure have a concomitant autoimmune disease. Cases of premature ovarian failure associated with Sj?gren syndrome have been reported in the literature. Patient and method: We report a case of a 42-year-old white woman with Sj?gren syndrome and premature ovarian failure who underwent a reversal of her premature ovarian failure and restoration of normal menses using an elimination diet protocol. The patient was diagnosed with her rheumatological condition in 2005 and started on disease-modifying antirheumatoid drugs, which were taken intermittently due to a concern over medicatio...

2010-01-01

168

Cardiac Channelopathies and Sudden Infant Death Syndrome

British Library Electronic Table of Contents (United Kingdom)

Abstract Sudden infant death syndrome (SIDS) is always a devastating and unexpected occurrence. SIDS is the leading cause of death in the first 6 months after birth in the industrialized world. Since the discovery in 1998 of long QT syndrome as an underlying substrate for SIDS, around 10-20% of SIDS cases have been proposed as being caused by genetic variants in either ion channel or ion channel-associated proteins. Until now, 10 cardiac channelopathy susceptibility genes have been found to be implicated in the pathogenesis of SIDS. Four of the genes encode cardiac ion channel a-subunits, 3 genes encode ion channel b-subunits, and 3 genes encode other channel-interacting proteins. All 10 genes have been associated with primary electrical heart diseases. SIDS may hereby be the initial sympt...

2011-01-01

169

aHUS caused by complement dysregulation: new therapies on the horizon

Use of a Cybex NORM dynamometer to assess muscle function in patients with thoracic cancer

Atypical hemolytic uremic syndrome (aHUS) is a heterogeneous disease that is caused by defective complement regulation in over 50% of cases. Mutations have been identified in genes encoding both complement...Full Text Available

2011-01-01

170

Urethral syndrome in women attending a clinic for sexually transmitted diseases.

BackgroundThe cachexia-anorexia syndrome impacts on patients' physical independence and quality of life. New treatments are required and need to be evaluated using acceptable and...Full Text Available

171

Type I Collagen Is a Genetic Modifier of Matrix Metalloproteinase 2 in Murine Skeletal Development

Of 107 women investigated for frequency of micturition and dysuria, 21 had gonorrhoea, 14 chlamydial urethritis, eight an Escherichia coli urinary tract infection, 18 candidosis, 12 trichomoniasis,...Full Text Available

1983-06-01

172

Transcatheter stent implantation to treat aortic coarctation in infancy.

Recessive inactivating mutations in human matrix metalloproteinase 2 (MMP2, gelatinase A) are associated with syndromes that include abnormal facial appearance, short stature, and severe bone...Full Text Available

2007-06-01

173

The use of etoricoxib to treat an idiopathic stabbing headache: a case report

A ten week old girl who had previously undergone a palliative procedure for the hypoplastic left heart syndrome had unrelieved aortic coarctation that did not respond to standard balloon dilatation....Full Text Available

1993-01-01

174

The role of DNA damage response pathways in chromosome fragility in Fragile X syndrome

According to the International Headache Society, idiopathic stabbing headache (ISH), an indomethacin-responsive headache syndrome, is a paroxysmal disorder of short duration manifested as head pain...Full Text Available

175

The Spectrum of Monogenic Autoinflammatory Syndromes: Understanding Disease Mechanisms and Use of Targeted Therapies

FRAXA is one of a number of fragile sites in human chromosomes that are induced by agents like fluorodeoxyuridine (FdU) that affect intracellular thymidylate levels. FRAXA coincides with a >200...Full Text Available

2009-07-01

176

The Burden of Common Infectious Disease Syndromes at the Clinic and Household Level from Population-Based Surveillance in Rural and Urban Kenya

Monogenic autoinflammatory diseases encompass a distinct and growing clinical entity of multisystem inflammatory diseases with known genetic defects in the innate immune system. The diseases...Full Text Available

2008-07-01

177

The Absence of the Verumontanum at Voiding Cystourethrography as a Sign of Prostate Maldevelopment

BackgroundCharacterizing infectious disease burden in Africa is important for prioritizing and targeting limited resources for curative and preventive services and monitoring the...Full Text Available

178

Successful establishment of primary small airway cell cultures in human lung transplantation

Prostate maldevelopment in prune-belly syndrome has only been described at necropsy. No reports are available in the “in vivo” studies. The absence of the verumontanum at voiding cystourethrography...Full Text Available

2011-01-01

179

Shiga Toxin Subtypes Display Dramatic Differences in Potency ?

BackgroundThe study of small airway diseases such as post-transplant bronchiolitis obliterans syndrome (BOS) is hampered by the difficulty in assessing peripheral airway function...Full Text Available

2009-01-01

180

Seroprevalence of HIV-1 and HIV-2 infection among children diagnosed with protein-calorie malnutrition in Nigeria.

Purified Shiga toxin (Stx) alone is capable of producing systemic complications, including hemolytic-uremic syndrome (HUS), in animal models of disease. Stx includes two major antigenic forms (Stx1...Full Text Available

2011-03-01

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181

Sequence variants of the DFNB31 gene among Usher syndrome patients of diverse origin

Excessive weight loss due to protein calorie malnutrition (PCM) is a significant problem in Nigerian children. This syndrome may be difficult to differentiate from the wasting disease caused by human...Full Text Available

1993-04-01

182

Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging?

PurposeIt has been demonstrated that mutations in deafness, autosomal recessive 31 (DFNB31), the gene encoding whirlin, is responsible for nonsyndromic hearing loss...Full Text Available

183

Rapidly Progressive Toxic Leukoencephalomyelopathy with Myelodysplastic Syndrome: a Clinicopathological Correlation

We have recently reported that progeroid Zmpste24^−/− mice, which exhibit multiple defects that phenocopy Hutchinson-Gilford progeria syndrome, show a profound dysregulation...Full Text Available

184

Probiotic treatment of irritable bowel syndrome in children

Neurological disorders induced by long-term exposure to organic solvents typically have a slowly progressive clinical course, which may be arrested or even reversed following discontinuation of exposure....Full Text Available

2007-03-01

185

Prevention of cardiovascular disease: Obesity, diabetes and the metabolic syndrome

Treatment of functional bowel disorders of irritable bowel-type (IBS) in children remains a difficult task because of a lack of drugs with low adverse event profile. We here report the results of a...Full Text Available

186

Pericardiectomy for Pleuropericardial Effusion Complicating Bacterial Pneumonia

The current obesity pandemic is expected to result in considerable downstream morbidity, mortality and incremental costs to health care systems around the world. The major metabolic complications of...Full Text Available

2010-08-01

187

Origin of XMRV and its Demise as a Human Pathogen Associated with Chronic Fatigue Syndrome

Severe pericardial effusion is a rare complication of bacterial pneumonia and it usually disappears under medical treatment. Herein we report a case of a girl with a congenital immunodeficient syndrome...Full Text Available

2010-01-01

188

Ophthalmic abnormalities in patients with cutaneous T-cell lymphoma.

Retroviruses are well known pathogens of mammals, birds and fish. Their potential to induce cancer in chickens was already described almost 100 years ago and murine retroviruses have been a subject...Full Text Available

189

Novel Pathologic Findings Associated with Urinary Retention in a Mouse Model of Mucopolysaccharidosis Type IIIB

PURPOSE: To determine the frequency of ophthalmic abnormalities in patients with cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome) and T-cell lymphoma involving the skin and...Full Text Available

1998-01-01

190

Misreporting of myocardial infarction end points: results of adjudication by a central clinical events committee in the PARAGON-B trial. Second Platelet IIb/IIIa Antagonist for the Reduction of Acute Coronary Syndrome Events in a Global Organization Network Trial.

Mucopolysaccharidosis type IIIB (MPS IIIB; Sanfilippo syndrome type B) is a metabolic disorder with devastating clinical characteristics starting in early childhood and leading to premature death. A...Full Text Available

2009-04-01

191

Mammalian life-span determinant p66^shcA mediates obesity-induced insulin resistance

PMID:11835026

2002-02-01

192

Lack of association between polymorphisms in C4b-binding protein and atypical haemolytic uraemic syndrome in the Spanish population

Obesity and metabolic syndrome result from excess calorie intake and genetic predisposition and are mechanistically linked to type II diabetes and accelerated body aging; abnormal nutrient and insulin...Full Text Available

2010-07-27

193

Lack of association between dietary fructose and hyperuricemia risk in adults

Dysregulation of the alternative pathway of complement activation, caused by mutations or polymorphisms in the genes encoding factor H, membrane co-factor protein, factor I or factor B, is associated...Full Text Available

2009-01-01

194

Kaposi's sarcoma involving the thyroid in a patient with AIDS

BackgroundHigh serum uric acid concentration (hyperuricemia) has been studied for its relationship with multiple adverse health outcomes, such as metabolic syndrome. Intervention...Full Text Available

195

Investigation and management of adrenal disease

A 30-year-old man with acquired immune deficiency syndrome (AIDS) and Kaposi's sarcoma had a palpable thyroid mass and cervical lymphadenopathy. Nuclear medicine and ultrasound scans revealed multiple thyroid nodules. Results of biopsy showed Kaposi's sarcoma metastatic to the thyroid.

196

British Library Electronic Table of Contents (United Kingdom)

Disorders of the adrenal gland are rare and complex, with many potential pitfalls in their management. An understanding of embryology, anatomy, physiology and biochemistry is crucial. Surgical treatment may be required for syndromes of hormonal excess and/or suspicion of neoplasia.

2011-01-01

197

Intravenous immunoglobulin in the treatment of primary trigeminal neuralgia refractory to carbamazepine: a study protocol[ISRCTN33042138

Hirschsprung disease associated with polydactyly, unilateral renal agenesis, hypertelorism, and congenital deafness: a new autosomal recessive syndrome.

BackgroundWe have recently reported successful treatment of patients with chronic pain syndromes using human pooled intravenous immunoglobulin (IVIG) in a prospective, open-label...Full Text Available

198

Herlyn-Werner-Wunderlich syndrome: uterus didelphys, blind hemivagina and ipsilateral renal agenesis. Sonographic and MR findings in 11 cases

An association of Hirschsprung disease with polydactyly, unilateral renal agenesis, hypertelorism, and congenital deafness is described in sibs (brother and sister) of consanguineous parents. It is...Full Text Available

1988-03-01

199

HIV/AIDS Counseling Skills and Strategies: Can Testing and Counseling Curb the Epidemic?

Uterus didelphys with obstructed hemivagina and ipsilateral renal agenesis is a rare entity, sometimes referred to as Herlyn-Werner-Wunderlich syndrome (HWW). It usually presents after menarche with progressive pelvic pain, sometimes with regular menses, and a palpable mass due to hemihaematocolpos. The diagnosis is generally made only if the suspicion of this genitourinary syndrome is raised. To highlight the imaging diagnostic clues in this rare condition. We report on 11 adolescents with this condition. Sonography mostly allowed the correct diagnosis by showing uterovaginal duplication, haematocolpos or haematometrocolpos, and the absence of the ipsilateral kidney. MRI provided more detailed information regarding uterine morphology, the continuity with each vaginal channel (obstructed and nonobstructed), and the bloody nature of the contents. Early and accurate diagnosis of this syndrome is important so that adequate and ...

2007-07-15

200

Factors influencing postoperative morbidity and mortality in patients treated with bleomycin.

Objectives:The human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) epidemic is in its third decade and has reached to alarming proportions worldwide....Full Text Available

2011-01-01

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201

Endovascular treatment of a Superior Mesenteric Artery Syndrome variant secondary to traumatic pseudoaneurysm

Patients treated with bleomycin are at risk of developing the acute adult respiratory distress syndrome post-operatively. In a prospective study of 12 patients who had received bleomycin preoperatively...Full Text Available

1978-06-24

202

Effect of Leucovorin (Folinic Acid) on the Developmental Quotient of Children with Down's Syndrome (Trisomy 21) and Influence of Thyroid Status

Pseudoaneurysms related to the superior mesenteric artery (SMA) are a recognised complication of trauma to the vessel, and successful treatment with stenting has been previously described. We report...Full Text Available

203

Defining and measuring the costs of the HIV epidemic to business firms.

BackgroundSeven genes involved in folate metabolism are located on chromosome 21. Previous studies have shown that folate deficiency may contribute to mental retardation in Down's...Full Text Available

204

Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations

Most published estimates of the costs of the epidemic of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) have been developed from the societal perspective,...Full Text Available

1994-05-01

205

Cortical auditory disorders: clinical and psychoacoustic features.

Carney-Stratakis syndrome, an inherited condition predisposing affected individuals to gastrointestinal stromal tumor (GIST) and paraganglioma, is caused by germline mutations in succinate dehydrogenase...Full Text Available

2011-01-04

206

Complement-fixing Activity of Fulvic Acid from Shilajit and Other Natural Sources

The symptoms of two patients with bilateral cortical auditory lesions evolved from cortical deafness to other auditory syndromes: generalised auditory agnosia, amusia and/or pure word deafness, and...Full Text Available

1988-01-01

207

Comparison of McAuley/fasting insulin indices with ATP III clinical criteria for the diagnosis of insulin resistance in type 2 diabetes mellitus

Shilajit has been used traditionally in folk medicine for treatment of a variety of disorders, including syndromes involving excessive complement activation. Extracts of Shilajit contain significant...Full Text Available

2009-03-01

208

Colonoscopic perforation leading to a diagnosis of Ehlers Danlos syndrome type IV: a case report and review of the literature

Objective:To estimate the prevalence of insulin resistant syndrome (IRS) among newly diagnosed patients with type 2 diabetes and to test their validity against two indices...Full Text Available

2011-07-01

209

Clinical effects of laparotomy with perioperative continuous peritoneal lavage and postoperative hemofiltration in patients with severe acute pancreatitis

IntroductionColonoscopic perforation is a rare but serious complication of colonoscopy. Factors known to increase the risk of perforation include colonic strictures, extensive diverticulosis,...Full Text Available

210

Chromosome X modulates incidence of testicular germ cell tumors in Ter mice

BackgroundThe elevated serum and peritoneal cytokine concentrations responsible for the systemic response syndrome (SIRS) and multiorgan failure in patients with severe acute pancreatitis...Full Text Available

211

Characterization of the binding sites for dicarboxylic acids on bovine serum albumin.

Germ cell tumor development in humans has been proposed to be part of testicular dysgenesis syndrome (TDS), which manifests as undescended testes, sterility, hypospadias, and, in extreme cases,...Full Text Available

2007-12-01

212

CDC - Seasonal Influenza (Flu) - Questions and Answers - Guillain...

Dicarboxylic acids are prominent features of several diseases, including Reye's syndrome and inborn errors of mitochondrial and peroxisomal fatty acid oxidation. Moreover, dicarboxylic acids are potentially...Full Text Available

1991-06-15

213

Association between a functional polymorphism in the serotonin transporter gene and diarrhoea predominant irritable bowel syndrome in women

Effectiveness Flu Shot Nasal Spray Vaccine (LAIV) Thimerosal Guillain-Barré Syndrome (GBS) Antiviral Drugs: Key Facts Antiviral Drugs: Q&A Antiviral Drug Resistance Links,...

2011-09-24

214

Alcohol and the fetus in the west of Scotland.

Background and aims: Serotonin (5-hydroxtryptamine, 5-HT) is an important factor in gut function, playing key roles in intestinal peristalsis and secretion, and in sensory...Full Text Available

2004-10-01

215

Abciximab: a reappraisal of its use in coronary care

Forty children with the fetal alcohol syndrome were identified in the west of Scotland. All were growth retarded and had abnormal facial features, and all those who were tested were found to have neurological...Full Text Available

1983-07-02

216

AICAR inhibits adipocyte differentiation in 3T3L1 and restores metabolic alterations in diet-induced obesity mice model

Platelet reactivity plays a pivotal role in the pathogenesis of ischemic adverse events during and after acute coronary syndromes (ACS), and percutaneous coronary intervention (PCI). Glycoprotein (GP)...Full Text Available

2008-03-01

217

A homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, ? cell hyperplasia, and islet cell tumor

BackgroundObesity is one of the principal causative factors involved in the development of metabolic syndrome. AMP-activated protein kinase (AMPK) is an energy sensor that regulates...Full Text Available

218

A diagnostic survey of infants referred for chromosome analysis in the neonatal period.

ObjectiveThe goal of the study was to investigate the genetic and molecular basis of a novel syndrome of marked hyperglucagonemia and pancreatic α cell hyperplasia...Full Text Available

2009-11-01

219

A Rare Null Allele Potentially Encoding a Dominant-Negative TRIM5? Protein in Baka Pygmies

Examination and assessment of 140 liveborn and stillborn infants referred within two weeks of birth for chromosome analysis showed that 48 had Down's syndrome, 12 other chromosome abnormalities, 17...Full Text Available

1980-10-18

220

A Rapid Murine Coma and Behavior Scale for Quantitative Assessment of Murine Cerebral Malaria

The global acquired immunodeficiency syndrome (AIDS) pandemic is thought to have arisen by the transmission of human immunodeficiency virus (HIV-1)-like viruses from chimpanzees in southeastern...Full Text Available

2009-08-15

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221

Various clinical situations and their influence on linear occlusion in treating combination syndrome: a discussion of treatment options.

BackgroundCerebral malaria (CM) is a neurological syndrome that includes coma and seizures following malaria parasite infection. The pathophysiology is not fully understood and cannot...Full Text Available

222

The advancement of stem cells in radiation medicine

Eliminating anterior tooth contact is paramount when treating combination syndrome. It is possible to do so through the use of linear occlusion with a non-interceptive arrangement and the bilateral fulcrum of protrusive stability. The presence of mandibular anterior teeth often complicates this procedure. When establishing the horizontal plane of occlusion, clinical circumstances often necessitate modifications; nevertheless, certain principles must be incorporated into the design of the prostheses. Clinical circumstances may dictate altering the approach but these principles must be maintained to eliminate anterior hyperfunction. PMID:15055634

223

Patterns of gallium-67 scintigraphy in patients with acquired immunodeficiency syndrome and the AIDS related complex

It may result in acute radiation syndrome after body is exposed to ionizing radiation. The one of long-term effects of irradiation injury is leukemia. The bone marrow cells (BMC) transplantation including stem cells is the only effective therapy for acute radiation syndrome patients. Recently, with the advancement of stem cell research that the stem cells have multipotential and can convert each other, it may supply the new stem source for the irradiation injury patients. At the same time with the further research of radioprotective reagents, the hematopoietic stem cells proliferation after irradiation injury is promoted

2003-02-01

224

Method for syndrome coding and its application to fast hardware data selection based on the processors operating in the GF(2sup(m)) Galois field

Thirty-two patients with AIDS related complex (ARC) or acquired immunodeficiency syndrome (AIDS) underwent /sup 67/Ga scans as part of their evaluation. Three patterns of /sup 67/Ga biodistribution were found: lymph node uptake alone; diffuse pulmonary uptake; normal scan. Gallium-67 scans were useful in identifying clinically occult Pneumocystis carinii pneumonia in seven of 15 patients with ARC who were asymptomatic and had normal chest radiographs. Gallium scans are a useful ancillary procedure in the evaluation of patients with ARC or AIDS.

1987-07-01

225

Mechanisms Underlying Visceral Hypersensitivity in Irritable Bowel Syndrome

The method of syndrome coding for data compression read out from multiwire proportional chambers that has been previously proposed is generalized in case of its application to registration of the coordinates of events detected. The questions of execution of arithmetic and algebraic operations on the Galois field elements and their hardware implementation are considered. The method of computation is presented of a specialized processor for parallel computing the coordinates of three sparks. The estimate of its speed is equal to 185 ns. Data compression, data selection and coordinate calculations are performed without use of memory elements and timing pulses.

226

British Library Electronic Table of Contents (United Kingdom)

Visceral hypersensitivity is currently considered a key pathophysiological mechanism involved in pain perception in large subgroups of patients with functional gastrointestinal disorders, including irritable bowel syndrome (IBS). In IBS, visceral hypersensitivity has been described in 20%?90% of patients. The contribution of the central nervous system and psychological factors to visceral hypersensitivity in patients with IBS may be significant, although still debated. Peripheral factors have gained increasing attention following the recognition that infectious enteritis may trigger the development of persistent IBS symptoms, and the identification of mucosal immune, neural, endocrine, microbiological, and intestinal permeability abnormalities. Growing evidence suggests that these factors ...

2011-01-01

227

Foraminal stenosis complicating retained broken epidural needle tip -A case report-.

Environmental tobacco smoke and sudden infant death syndrome: a review

Lumbar epidural anesthesia is useful in a variety of chronic benign pain syndromes, including lumbar radiculopathy, low back pain syndrome, spinal stenosis, and vertebral compression fractures. Given the increased number of epidural nerve blocks being performed, some have reported unexplained complications of a transient or permanent nature and with varying degrees of severity. However, no case has been reported of a broken epidural needle tip retained in the lumbar facet joint area. This represents the first reported case presentation of foraminal stenosis developing in a patient after a retained epidural needle tip. PMID:21286465

2010-12-31

228

British Library Electronic Table of Contents (United Kingdom)

Environmental tobacco smoke (ETS), containing the developmental neurotoxicant, nicotine, is a prevalent component of indoor air pollution. Despite a strong association with active maternal smoking and sudden infant death syndrome (SIDS), information on the risk of SIDS due to prenatal and postnatal ETS exposure is relatively inconsistent. This literature review begins with a discussion and critique of existing epidemiologic data pertaining to ETS and SIDS. It then explores the biologic plausibility of this association, with comparison of the known association between active maternal smoking and SIDS, by examining metabolic and placental transfer issues associated with nicotine, and the biologic responses and mechanisms that may follow exposure to nicotine. Evidence indicates that prenatal ...

2006-01-01

229

Diagnosis and therapy of Budd-Chiari syndrome; Diagnostik und Therapie des Budd-Chiari-Syndroms

Purpose: Budd-Chiari syndrome is a fairly uncommon disease in Europe. This often leads to its late diagnosis. The syndrome is characterised by portal hypertension and splanchnic congestion due to obstruction of hepatic venous outflow. This paper describes the treatment of three patients with Budd-Chiari syndrome by interventional therapeutic techniques and discusses alternative treatment modalities. Patients and Methods: The first patient presented with veno-occlusive disease and was treated by the placement of a transjugular intrahepatic portosystemic stentshunt. The second patient showed an occlusion of the major hepatic veins. After percutaneous recanalisation, a stent was placed in the right hepatic vein which remained patent. The third patient had a membranous obstruction of the right hepatic vein which was treated by percutaneous balloon dilatation. Results: In all patients the clinical symptoms resolved completely ...

1998-09-01

230

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Gender gap in maths test scores in South Korea and Hong Kong: Role of family background and single-sex schooling

...The RSPB: Birds by family: Owls E-mail to a friendE-newsletterContact us Home England Northern Ireland Scotland Wales About Overview Awards & recognition Contact ...Birds by family PrintHome Birds and wildlife Bird guide Birds by family Owls Owls Owls are specialised birds with round heads and rather flat ...or dished faces, with forward-facing eyes and a short, hooked bill. Most are nocturnal or crepuscular (active at dawn and dusk)... Owls are found all over the temperate and tropical parts of the world. Barn owl With heart shaped face, buff back ...

231

British Library Electronic Table of Contents (United Kingdom)

In many industrialised societies, women remain underrepresented in the sciences, which can be predicted by the gender gap in math achievement at school. Using PISA 2006 data, we explore the role of family background and single-sex schooling in girls' disadvantage in maths in South Korea and Hong Kong. This disadvantage is found to be associated with single-sex schooling, but not with family background. Attending a girls' school confers a benefit only in South Korea, whereas the gendered curriculum counteracts the selectivity advantage of girls' schools in Hong Kong. We find that a gendered social structure prevalent in both societies.

2012-01-01

232

Diquarks from a fourth family

What Would Major General John A. Lejeune Think?

If fourth family condensates are responsible for electroweak symmetry breaking then they may also break approximate global symmetries. Among the resulting pseudo-Goldstone bosons are those that can have diquark quantum numbers. We describe the variety of diquarks and their decay modes, and we find aspects that are particular to the fourth family framework. Spectacular signatures at the LHC appear and are explored for color sextet diquarks with 600 GeV mass. We consider a simple search strategy which avoids diquark reconstruction. We also consider 350 GeV mass diquarks that are accessible at the Tevatron.

2011-01-01

233

Vehicle-Dependent Disposition Kinetics of Fluoranthene in Fisher-344 Rats

... In the general portion of the article it states, that no more than three family members are authorized a one time travel and per diem for ...

2005-02-08

234

Variability in Melanoma Metalloproteinase Expression Profiling

The objective of this study was to evaluate how the vehicles of choice affect the pharmacokinetics of orally administered Fluoranthene [FLA] in rats. Fluoranthene is a member of the family of...Full Text Available

2008-03-01

235

The structure of receptor-associated protein (RAP)

The proteolytic activities of a disintegrin and metalloproteinase (ADAM); a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS), and matrix metalloproteinase (MMP) families play important...Full Text Available

2010-12-01

236

The effect of family processes on school achievement as moderated by socioeconomic context

The receptor-associated protein (RAP) is a molecular chaperone that binds tightly to certain newly synthesized LDL receptor family members in the endoplasmic reticulum (ER) and facilitates their delivery...Full Text Available

2007-08-01

237

British Library Electronic Table of Contents (United Kingdom)

This longitudinal study examined a model of early school achievement in reading and math, as it varies by socioeconomic context, using data from the NICHD Study of Early Child Care and Youth Development. A conceptual model was tested that included features of family stress, early parenting, and school readiness, through both a single-group analysis and also a multiple-group analysis. Latent profile analysis was used to identify subgroups of more advantaged and less advantaged families. Family stress and parenting were shown to operate differently depending on the socioeconomic context, whereas child-based school readiness characteristics were shown to operate similarly across socieodemographic contexts. Implications for intervention are discussed.

2011-01-01

238

Studies for the Synthesis of Xenicane Diterpenes. A Stereocontrolled Total Synthesis of 4-Hydroxydictyolactone

Strikingly different penetrance of LHON in two Chinese families with primary mutation G11778A is independent of mtDNA haplogroup background and secondary mutation G13708A

The stereocontrolled total synthesis of 4-hydroxydictyolactone (4), a member of the xenicane diterpene family of natural products, is described. These studies feature the development...Full Text Available

2009-07-01

239

British Library Electronic Table of Contents (United Kingdom)

The penetrance of Lebers hereditary optic neuropathy (LHON) in families with primary mitochondrial DNA (mtDNA) mutations is very complex. Matrilineal and nuclear genetic background, as well as environmental factors, have been reported to be involved in different affected pedigrees. Here we describe two large Chinese families that show a striking difference in the penetrance of LHON, in which 53.3% and 15.0% of members were affected (Pin vivo mitochondrial oxidative metabolism as described in a previous study. Evolutionary analysis failed to indicate any putatively pathogenic mutation that cosegregated with G11778A in these two pedigrees. Our results suggest that the variable penetrance of LHON in the two Chinese families is independent of both their mtDNA haplotype background and a seconda...

2008-01-01

240

Sirtuins, Bioageing, and Cancer

Predictors of Fat Stereotypes among 9-Year-Old Girls and Their Parents

The Sirtuins are a family of orthologues of yeast Sir2 found in a wide range of organisms from bacteria to man. They display a high degree of conservation between species, in both sequence and function,...Full Text Available

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241

Phospholemman: A Novel Cardiac Stress Protein

ObjectiveTo assess familial links in fat stereotypes and predictors of stereotypes among girls and their parents.Research Methods and...Full Text Available

2004-01-01

242

Mutations in RNA Binding Protein Gene Cause Familial Dilated Cardiomyopathy

Phospholemman (PLM), a member of the FXYD family of regulators of ion transport, is a major sarcolemmal substrate for protein kinases A and C in cardiac and skeletal muscle. In the heart, PLM...Full Text Available

2010-08-01

243

Model for assessing psychosocial problems.

ObjectivesWe sought to identify a novel gene for dilated cardiomyopathy (DCM).BackgroundDCM is a heritable, genetically...Full Text Available

2009-09-01

244

Mental Health and Traumatic Events

The Model for the Assessment of Psychosocial Problems (MAPP) can help family medicine residents effectively assess patients with psychosocial problems. Following a patient-centred clinical method, MAPP...Full Text Available

1996-02-01

245

Is Maternal Marriage Beneficial for Low-Income Adolescents?

News Jobs Grants/Funding Families Prevention Diseases Regulations Preparedness Mental Health and Traumatic Events Find Local Mental Health Services Information for: Parents and...

2011-08-27

246

Human endogenous retroviruses: transposable elements with potential ?

The present study investigated the association of mothers’ marriage and changes in young adolescents’ cognitive and socioemotional development and changes in family processes....Full Text Available

2009-01-01

247

Homocysteine and Familial Longevity: The Leiden Longevity Study

Human endogenous retroviruses (HERVs) are a significant component of a wider family of retroelements that constitute part of the human genome. These viruses, perhaps representative of previous exogenous...Full Text Available

2004-10-01

248

Homocysteine concentrations are a read-out of methionine metabolism and have been related to changes in lifespan in animal models. In humans, high homocysteine concentrations are an important predictor...Full Text Available

249

Gynecologic Pelvic Pain

Floral ontogeny of Annonaceae: evidence for high variability in floral form

The family physician dealing with gynecologic pelvic pain (acute or chronic) enters at the beginning of the problem as diagnostician, refers the patient to a specialist in the interim, and resumes...Full Text Available

1989-06-01

250

Evolution of fruit and seed characters in the Diervilla and Lonicera clades (Caprifoliaceae, Dipsacales)

Background and AimsAnnonaceae are one of the largest families of Magnoliales. This study investigates the comparative floral development of 15 species to understand the basis for...Full Text Available

2010-10-01

251

Congenital nephrogenic diabetes insipidus in a baby girl.

Background and AimsThe Diervilla and Lonicera clades are members of the family Caprifoliaceae (Dipsacales sensu Full Text Available

2009-08-01

252

Choosing a Microcomputer: What to Look For and What to Avoid

A 6-week-old girl with fever, hypernatraemia, dehydration, and polyuria failed to concentrate urine in response to exogenous vasopressin administration. There was no family history of nephrogenic diabetes...Full Text Available

1978-11-01

253

Children of men with alcohol dependence: Psychopathology, neurodevelopment and family environment

Many family physicians are considering purchasing a computer in the near future. This article explains some of the jargon of the computer industry and describes the various specifications that will...Full Text Available

1984-04-01

254

Caenorhabditis elegans Pheromones Regulate Multiple Complex Behaviors

Background:Children of people with alcohol dependence (COAs) are at high risk for behavioral and cognitive problems.Aim:Aim of...Full Text Available

2010-10-01

255

Association and expression study of synapsin III and schizophrenia

Summary of recent advancesA family of small molecules called ascarosides act as pheromones to control multiple behaviors in the nematode Caenorhabditis elegans....Full Text Available

2009-08-01

256

Analysis of codon usage and nucleotide composition bias in polioviruses

The synapsin III gene, SYN3, which belongs to the family of synaptic vesicle-associated proteins, has been implicated in the modulation of neurotransmitter...Full Text Available

2009-11-20

257

A PRELIMINARY PHYLOGENETIC ANALYSIS OF METAPENAEOPSIS (DECAPODA: PENAEIDAE) BASED ON MITOCHONDRIAL DNA SEQUENCES OF ...

BackgroundPoliovirus, the causative agent of poliomyelitis, is a human enterovirus and a member of the family of Picornaviridae and among the most rapidly evolving viruses known....Full Text Available

258

... each species studied are listed in Table 1. Penaeus monodon Fabricius, 1798 (family Penaeidae) and Solenocera koelbeli De Man, ... ...

259

The Sorcerer II Global Ocean Sampling Expedition: Expanding theUniverse of Protein Families

OBJECTIVE: To evaluate the effectiveness of a program to improve hypertension control practices in primary care. DESIGN: Retrospective quasi-experimental study. SETTING: Three hospital-based family...Full Text Available

1994-10-01

260

Relationships Between Level and Change in Family, School, and Peer Factors During Two Periods of Adolescence and Problem Behavior at Age 19

Metagenomics projects based on shotgun sequencing of populations of micro-organisms yield insight into protein families. We used sequence similarity clustering to explore proteins with a comprehensive dataset consisting of sequences from available databases together with 6.12 million proteins predicted from an assembly of 7.7 million Global Ocean Sampling (GOS) sequences. The GOS dataset covers nearly all known prokaryotic protein families. A total of 3,995 medium- and large-sized clusters consisting of only GOS sequences are identified, out of which 1,700 have no detectable homology to known families. The GOS-only clusters contain a higher than expected proportion of sequences of viral origin, thus reflecting a poor sampling of viral diversity until now. Protein domain distributions in the GOS dataset and current protein databases show distinct biases. Several protein domains that were previously categorized as kingdom ...

2006-03-23

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261

Conformational Changes in BAK, a Pore-forming Proapoptotic Bcl-2 Family Member, upon Membrane Insertion and Direct Evidence for the Existence of BH3-BH3 Contact Interface in BAK Homo-oligomers*

While prior research has examined family, school, and peer factors as potential predictors of problem behavior, less attention has been given to studying when these factors are most predictive...Full Text Available

2010-06-01

262

A new sixth-order scheme for nonlinear equations

During apoptosis, the pro-apoptotic Bcl-2 family proteins BAK and BAX form large oligomeric pores in the mitochondrial outer membrane. Apoptotic factors, including cytochrome c, are...Full Text Available

2010-09-10

263

British Library Electronic Table of Contents (United Kingdom)

In this paper we present a new efficient sixth-order scheme for nonlinear equations. The method is compared to several members of the family of methods developed by Neta (1979) [B. Neta, A sixth-order family of methods for nonlinear equations, Int. J. Comput. Math. 7 (1979) 157-161]. It is shown that the new method is an improvement over this well known scheme.

2012-01-01

264

A Systematic Framework for the Construction of Optimal Complete Complementary Codes

Defecographic diagnosis of the puborectalis syndrome; Diagnosi mediante defecografia della sindrome del muscolo puborettale

The complete complementary code (CCC) is a sequence family with ideal correlation sums which was proposed by Suehiro and Hatori. Numerous literatures show its applications to direct-spread code-division multiple access (DS-CDMA) systems for inter-channel interference (ICI)-free communication with improved spectral efficiency. In this paper, we propose a systematic framework for the construction of CCCs based on $N$-shift cross-orthogonal sequence families ($N$-CO-SFs). We show theoretical bounds on the size of $N$-CO-SFs and CCCs, and give a set of four algorithms for their generation and extension. The algorithms are optimal in the sense that the size of resulted sequence families achieves theoretical bounds and, with the algorithms, we can construct an optimal CCC consisting of sequences whose lengths are not only almost arbitrary but even variable between sequence families. We also discuss the ...

2010-01-01

265

Defecographic diagnosis of the puborectalis syndrome

The puborectalis syndrome is a defecation disorder supported by the nonrelaxation of puborectalis sling with consequent dyschezia. They report on a series of 98 patients submitted to clinical examination, defecography, anorectal manometry, electromyography and intestinal transit time studies. The main symptoms of puborectalis syndrome in their patients were incomplete defecation (89 %) and intermittent evacuation (63 %); 28 % of patients turned to finger defecation. In all patients, defecography showed an abnormal increase in puborectalis impression on the posterior anorectal wall, reduced anorectal angle opening under straining (mean value: 113 deg) and prolonged expulsion time with barium pooling in the ampulla (mean evacuation time: 38 seconds). Such anorectal abnormalities as rectal mucosal prolapse (47 cases) and anterior rectocele (36 cases) were also associated. In 33 of 98 patients (34 % of cases), sling assessment by bidigital ...

1997-04-01

266

Organ culture of mammalian skin and the effects of ultraviolet light and testosterone on melanocyte morphology and function

The puborectalis syndrome is a defecation disorder supported by the nonrelaxation of puborectalis sling with consequent dyschezia. They report on a series of 98 patients submitted to clinical examination, defecography, anorectal manometry, electromyography and intestinal transit time studies. The main symptoms of puborectalis syndrome in their patients were incomplete defecation (89 %) and intermittent evacuation (63 %); 28 % of patients turned to finger defecation. In all patients, defecography showed an abnormal increase in puborectalis impression on the posterior anorectal wall, reduced anorectal angle opening under straining (mean value: 113 deg) and prolonged expulsion time with barium pooling in the ampulla (mean evacuation time: 38 seconds). Such anorectal abnormalities as rectal mucosal prolapse (47 cases) and anterior rectocele (36 cases) were also associated. In 33 of 98 patients (34 % of cases), sling assessment by bidigital ...

267

Complications of gallstone disease: Mirizzi syndrome, cholecystocholedochal fistula, and gallstone ileus.

Scrotal skin of black Long-Evans rats and human thigh skin were maintained in vitro as organ cultures for as long as 14 days, and examined histologically using the combined skin splitting and Dopa techniques. Selected rat skin cultures received testosterone in the culture medium and/or were irradiated with ultraviolet light (290 to 320 nm uvl). With increased time in culture, scrotal melanocytes round up and there is an increase in epidermal pigmentation. Human skin behaves similarly; after eight days in vitro human melanocytes also become rounded, but remain strongly Dopa-positive. Addition of exogenous testosterone to cultured rat skin maintains dendritic morphology of melanocytes, but cell body size is still reduced. uvl irradiation stimulates melanocytes in rat skin cultures, maintaining their dendritic morphology and increasing epidermal and dermal pigmentation. Cultured skin receiving both uvl and testosterone illustrates a synergistic effect. Electron ...

1978-05-01

268

A new plateau in the dose-survival-time response of the golden hamster (Mesocricetus auratus) from whole body irradiation

Gallstone is a common disease with a 10% prevalence in the United States and Western Europe. However, it is only symptomatic in 20-30% of patients, with biliary pain "colic" being the most common symptom. Complications of asymptomatic gallstone disease are generally rare, with an incidence of <1 %/yr. The most common complications of gallstone disease are acute cholecystitis, acute pancreatitis, ascending cholangitis, and gangrenous gallbladder. Less frequent complications include Mirizzi syndrome, cholecystocholedochal fistula, and gallstone ileus. Mirizzi syndrome and cholecystocholedochal fistula are two manifestations of the same process that starts with impaction of a gallstone in the gallbladder neck that results in obstruction of the bile duct, causing jaundice. The gallstone may erode into the bile duct, causing cholecystocholedochal fistula. Gallstone ileus refers to small bowel obstruction resulting from the impaction of one or ...

2002-02-01

269

Venous Thoracic Outlet Compression and the Paget-Schroetter Syndrome: A Review and Recommendations for Management

The survival time of golden hamsters (Mesocricetus auratus) after whole-body "6"0Co-#gamma#-irradiation in the range of 600 to 200 000 rad was investigated. The two plateaus of the dose-survival curve which correspond to bone marrow and gastrointestinal death are similar to those of other species such as mice, rats and mongolian gerbils. A new plateau occurring 40-57 hours after doses of 30 000-60 000 rad, where there is a little reduction in survival time, has been found. It is in addition to the well recognized central nervous system (CNS) syndrome. This plateau is observed only in golden hamsters, presumably because of their relatively high resistance to CNS syndrome. Experiments involving partial body irradiation of the animals indicate that the target is in the cephalic one-third of abdomen. The new segment may well indicate a new type of acute somatic radiation injury different from the well known bone marrow, gastrointestinal and CNS ...

1981-01-01

270

British Library Electronic Table of Contents (United Kingdom)

Paget Schroetter syndrome, or effort thrombosis of the axillosubclavian venous system, is distinct from other forms of upper limb deep vein thrombosis. It occurs in younger patients and often is secondary to competitive sport, music, or strenuous occupation. If untreated, there is a higher incidence of disabling venous hypertension than was previously appreciated. Anticoagulation alone or in combination with thrombolysis leads to a high rate of rethrombosis. We have established a multidisciplinary protocol over 15?years, based on careful patient selection and a combination of lysis, decompressive surgery, and postoperative percutaneous venoplasty. During the past 10?years, a total of 232 decompression procedures have been performed. This article reviews the literature and presents the Exet...

2011-01-01

271

The role of MRI in the diagnosis of recurrent/persistent carpal tunnel syndrome: A radiological and intra-operative correlation

British Library Electronic Table of Contents (United Kingdom)

MRI (Magnetic resonance imaging) has been widely used in the diagnosis of primary carpal tunnel syndrome (CTS). However, it has had limited clinical application in diagnosing persistent or recurrent CTS. We aimed to investigate the efficacy of this imaging modality in patients who had previously undergone open carpal tunnel release without relief of symptoms, and assess the correlation of MRI with intra-operative findings upon re-exploration. MRI studies were performed on 17 wrists (16 patients) presenting with recurrent/persistent symptoms and signs of CTS in whom repeat nerve conduction studies were also performed. Surgical re-exploration was undertaken on 16 wrists in which a 100% correlation was noted between MRI and intra-operative findings of an incompletely released or re-grown tran...

2011-01-01

272

The relationship between periodontitis and metabolic syndrome among a Korean nationally representative sample of adults

British Library Electronic Table of Contents (United Kingdom)

Abstract Aims: The aim of this study was to examine whether metabolic syndrome (MS) is associated with periodontitis in a representative sample of Korean adults, who were involved in the Fourth Korea National Health and Nutrition Examination Survey (KNHANES). Materials and Methods: A total of 7178 subjects over the age of 19 years who participated in KNHANES were examined. MS was defined as the definition proposed by the National Cholesterol Education Program Adult Treatment Panel III and the abdominal obesity cut-off line based on Korean Society for the Study of Obesity. The periodontal status was assessed by the Community Periodontal Index. Multivariate logistic regression analysis was carried out adjusting for the sociodemographics, oral health behaviours and status, and health behaviou...

2011-01-01

273

The effect of visual spatial attention on audiovisual speech perception in adults with Asperger syndrome

British Library Electronic Table of Contents (United Kingdom)

Individuals with Asperger syndrome (AS) have problems in following conversation, especially in the situations where several people are talking. This might result from impairments in audiovisual speech perception, especially from difficulties in focusing attention to speech-relevant visual information and ignoring distracting information. We studied the effect of visual spatial attention on the audiovisual speech perception of adult individuals with AS and matched control participants. Two faces were presented side by side, one uttering /aka/ and the other /ata/, while an auditory stimulus of /apa/ was played. The participants fixated on a central cross and directed their attention to the face that an arrow pointed to, reporting which consonant they heard. We hypothesized that the adults wi...

2011-01-01

274

Structured exercise training programme versus hypocaloric hyperproteic diet in obese polycystic ovary syndrome patients with anovulatory infertility: a 24-week pilot study

British Library Electronic Table of Contents (United Kingdom)

BACKGROUNDLifestyle modifications are successfully employed to treat obese and overweight women with polycystic ovary syndrome (PCOS). The aims of the current pilot study were (i) to compare the efficacy on reproductive functions of a structured exercise training (SET) programme with a diet programme in obese PCOS patients and (ii) to study their clinical, hormonal and metabolic effects to elucidate potentially different mechanisms of action.METHODSForty obese PCOS patients with anovulatory infertility underwent a SET programme (SET group, n = 20) and a hypocaloric hyperproteic diet (diet group, n = 20). Clinical, hormonal and metabolic data were assessed at baseline, and at 12- and 24-week follow-ups. Primary endpoint was cumulative pregnancy rate.RESULTSThe two groups had similar demogra...

2008-01-01

275

Severe immune haemolytic anaemia due to ceftriaxone in a patient with congenital nephrotic syndrome

British Library Electronic Table of Contents (United Kingdom)

Abstract Aim:- To describe the first case of ceftriaxone-related haemolysis in a patient with congenital nephrotic syndrome (CNS). Background:- Severe haemolysis caused by an immune reaction to ceftriaxone has mostly been described in patients with underlying haematological or immune dysfunction. Case report:- The authors present a 20-month-old boy with CNS of the Finnish type with several previous severe infections treated with ceftriaxone, admitted for suspected sepsis. Following ceftriaxone administration he developed shock secondary to an acute haemolytic reaction, with severe anaemia. Hypersensitivity to ceftriaxone was documented through positive agglutination tests. Conclusion:- Onset of haemolysis following ceftriaxone administration, particularly in a patient previously exposed to...

2011-01-01

276

No detectable XMRV in subjects with chronic fatigue syndrome from Quebec

British Library Electronic Table of Contents (United Kingdom)

We investigated the presence of XMRV in a cohort of Quebec patients with chronic fatigue syndrome (CFS). DNA was purified from activated peripheral blood mononuclear cells (PBMCs) and PCR was used to detect XMRV gag and env in 72 patients. Anti-XMRV antibodies were searched in sera of 62 patients by Western blot analysis. Attempts to detect XMRV antigens was made, using immunofluorescence with Gag anti-p30 antiserum on activated PBMC from 50 patients. Plasma viremia was measured by RT-PCR on 9 subjects. Finally, detection of infectious virus in 113 CFS subjects was made by co-culture of PHA+IL-2 activated PBMC with human LNCaP carcinoma cells, and by infecting the same susceptible cells with plasma, using a reverse transcriptase (RT) assay as a readout in both experiments. No detection of ...

2011-01-01

277

Metabolic and molecular stress responses of gilthead seam bream Sparus aurata during exposure to low ambient temperature: an analysis of mechanisms underlying the winter syndrome

British Library Electronic Table of Contents (United Kingdom)

The winter syndrome in the gilthead sea bream Sparus aurata indicates that the species is exposed to critically low temperatures in Mediterranean aquaculture in winter. The present study of metabolic patterns and molecular stress responses during cold exposure was carried out to investigate this ?disease?, in light of the recent concept of oxygen and capacity limited thermal tolerance. The metabolic profile of fuel oxidation was examined by determining the activities of the enzymes hexokinase (HK), aldolase (Ald), pyruvate kinase (PK), l-lactate dehydrogenase (l-LDH), citrate synthase (CS), malate dehydrogenase (MDH) and 3-hydroxyacyl CoA dehydrogenase (HOAD) in heart, red and white muscle after exposure to temperatures of 10, 14 and 18?C. Especially, the increase in LDH activity combined ...

2010-01-01

278

Laparoscopy and intersex: report of 5 cases of male pseudohermaphroditism.

KMeyeDB: a graphical database of mutations in genes that cause eye diseases

From May, 1999 to August, 2006, we performed laparoscopic diagnosis and treatment for 103 cases of impalpable testes. Among those we found 5 cases of male pseudohermaphroditism of different etiologies. Three males presented by impalpable testes with ambiguous genitalia and 2 females presented by primary amenorrhea. All of them have 46-XY normal male chromosomal pattern. In the first 3 cases, the etiology was complete gonadal dysgenesis, and 2 cases with persistent Mullerian syndrome. Timed gonadectomy for the first case and laparoscopic orchiopexy for the other 2 cases were performed. For the other 2 female cases, the etiology was complete androgen insensitivity syndrome and laparoscopic bilateral orchiectomy was performed for both of them. All the procedures were done without complications with satisfactory results. PMID:18319558

2008-02-01

279

British Library Electronic Table of Contents (United Kingdom)

KMeyeDB () is a database of human gene mutations that cause eye diseases. We have substantially enriched the amount of data in the database, which now contains information about the mutations of 167 human genes causing eye-related diseases including retinitis pigmentosa, cone-rod dystrophy, night blindness, Oguchi disease, Stargardt disease, macular degeneration, Leber congenital amaurosis, corneal dystrophy, cataract, glaucoma, retinoblastoma, Bardet-Biedl syndrome, and Usher syndrome. KMeyeDB is operated using the database software MutationView, which deals with various characters of mutations, gene structure, protein functional domains, and polymerase chain reaction (PCR) primers, as well as clinical data for each case. Users can access the database using an ordinary Internet browser wi...

2010-01-01

280

Honokiol enhances adipocyte differentiation by potentiating insulin signaling in 3T3-L1 preadipocytes

British Library Electronic Table of Contents (United Kingdom)

Adipose tissue plays an essential role in energy homeostasis as a metabolic and endocrine organ. Accordingly, adipocytes are emerging as a major drug target for obesity and obesity-mediated metabolic syndrome. Dysfunction of enlarged adipocytes in obesity is involved in obesity-mediated metabolic syndrome. Adipocytokines, such as adiponectin released from small adipocytes, are able to prevent these disorders. In this study, we found that honokiol, an ingredient of Magnolia officinalis used in traditional Chinese and Japanese medicines, enhanced adipocyte differentiation in 3T3-L1 preadipocytes. Oil Red O staining showed that treatment with honokiol in the presence of insulin dose-dependently increased lipid accumulation in 3T3-L1 preadipoyctes although its activity was weak compared with r...

2011-01-01

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281

Hearing loss in Turner syndrome

British Library Electronic Table of Contents (United Kingdom)

ObjectiveTo address the characteristics of hearing loss in patients with Turner syndrome (TS), we evaluated hearing levels of patients with TS and analyzed causative factors.Study designThirty-three patients with TS (8 to 40 years of age) were studied through the use of audiological measurements, and causative factors were explored.ResultsTwenty cases (35 of 66 ears tested) showed high-frequency (8 kHz) sensory neural hearing loss (HFQ-SNHL). Fifteen cases (26 ears) and 15 cases (24 ears) of the impaired 20 cases were unresponsive to distortion-product otoacoustic emissions and transient-evoked otoacoustic emissions, respectively. HFQ-SNHL showed little relation to the history of middle ear infection and puberty, although middle ear infections were seen in 11 of the 20 cases. The hearing t...

2006-01-01

282

Fish intake and acute coronary syndrome

British Library Electronic Table of Contents (United Kingdom)

Aims To study the effect of fish consumption on the risk of acute coronary syndrome (ACS) in healthy subjects. Methods and results This Danish follow-up study included 57 053 men and women between 50 and 64 years. Intake of lean and fatty fish was estimated from a detailed and validated food frequency questionnaire. Potential cases of ACS were identified through nationwide medical databases. A total of 1122 cases of ACS were verified during a mean follow-up period of 7.6 years. Among men, intake of fatty fish was associated with a lower risk of ACS. For men in the highest quintile of fish intake compared with the lowest quintile, the hazard ratio was 0.67 (95% confidence interval: 0.53-0.85). The inverse association was observed for intakes >6 g of fatty fish per day with no obvious additi...

2010-01-01

283

Detecting retroviral sequences in chronic fatigue syndrome.

Concurrent immune thrombocytopenic purpura and Guillain-Barre syndrome in a patient with Hashimotos thyroiditis

XMRV or xenotropic murine leukemia virus-related retrovirus, a recently discovered retrovirus, has been linked to both prostate cancer and chronic fatigue syndrome (CFS). Recently, the teams of Drs. Shyh-Ching Lo and Harvey Alter discovered the presence of sequences closely related to XMRV in the blood of 86.5% of patients with CFS [1]. These findings are important because since the initial discovery of XMRV in CFS, several studies have failed to find XMRV in specimens collected from CFS patients. While the current study also did not find XMRV in CFS, Lo et al. did detect sequences that belong to polytropic mouse endogenous retroviruses (PMV), which share considerable similarity with XMRV. Criteria for future studies that will help bring greater clarity to the issue of retroviral sequences in CFS are proposed below. PMID:21994623

2010-11-03

284

British Library Electronic Table of Contents (United Kingdom)

Immune thrombocytopenic purpura (ITP), Guillain-Barre syndrome (GBS), and Hashimotos thyroiditis (HT) are autoimmune disorders caused by impaired self-tolerance mechanisms triggered by interaction between genetic and environmental factors. ITP is an immune-mediated destruction of platelets resulting in mucocutaneous bleeding, GBS is an ascending motor paralysis caused by an inflammatory demyelination of peripheral nerves, and HT is characterized by autoimmune-mediated destruction of the thyroid gland. The concurrent development of ITP and GBS has only rarely been reported in the literature, and GBS itself rarely occurs with other autoimmune disorders. We present a 21 year-old patient with known Hashimotos hypothyroidism that simultaneously developed GBS and ITP after an upper respiratory t...

2007-01-01

285

Benign lymphoepithelial lesion of the parotid gland in AIDS patients: CT characteristics

Analysis of cerebrospinal fluid from chronic fatigue syndrome patients for multiple human ubiquitous viruses and xenotropic murine leukemia-related virus

Contrast agent-enhanced CT scans in nine male patients with histologically proved benign lymphoepithelial lesions of the perotid gland were reviewed. All scans showed cystic-appearing masses with peripheral rim enhancement corresponding to the macroscopic appearance of the lesion. Five patients were seropositive for human immunodeficiency virus (HIV) infection or had infections seen in acquired immunodeficiency syndrome. Three patients were members of high-risk groups. Only one patient had symptoms of the SICCA syndrome. Once a rare cause of parotid gland enlargement, benign lymphoepithelial lesions have recently been seen with increasing frequency in patients with HIV infection. Although the CT appearance is not pathognomic, correlation results of aspiration cytology and with clinical history can lead to a preoperative diagnosis of a benign lymphoepithelial lesion.

286

British Library Electronic Table of Contents (United Kingdom)

Abstract Recent reports showed many patients with chronic fatigue syndrome (CFS) harbor a retrovirus, xenotropic murine leukemia-related virus (XMRV), in blood; other studies could not replicate this finding. A useful next step would be to examine cerebrospinal fluid, because in some patients CFS is thought to be a brain disorder. Finding a microbe in the central nervous system would have greater significance than in blood because of the integrity of the blood-brain barrier. We examined cerebrospinal fluid from 43 CFS patients using polymerase chain reaction techniques, but did not find XMRV or multiple other common viruses, suggesting that exploration of other causes or pathogenetic mechanisms is warranted. Ann Neurol 2011;

2011-01-01

287

A PAC containing the human mitochondrial DNA polymerase gamma gene (POLG) maps to chromosome 15q25

The impact of stellar model spectra in disc detection

The human mitochondrial DNA (mtDNA) is a closed circular, 16,569-bp double-stranded DNA, encoding 13 genes whose protein products are subunits of the oxidative phosphorylation system required for synthesis of most of the ATP consumed by eukaryotic cells. Point mutations of the mtDNA that cause multi-tissue, loss-of-energy syndromes, called mitochondrial encephalomyopathies (e.g., MERRF and MELAS), have been identified. In addition, large-scale deletions of the human mtDNA have been identified and are the molecular bases for the neonatal and adolescent onset loss-of-energy syndromes Pearson and Kearns-Sayer, respectively. 5 refs., 1 fig.

1997-03-01

288

British Library Electronic Table of Contents (United Kingdom)

Abstract We present a study of the impact of different model groups in the detection of circumstellar debris discs. Almost all previous studies in this field have used kurucz (atlas9) model spectra to predict the stellar contribution to the flux at the wavelength of observation, thus determining the existence of a disc excess. Only recently have other model groups or families like marcs and nextgen (phoenix) become available to the same extent as atlas9. This study aims to determine whether the predicted stellar flux of a disc target can change with the choice of model family can a disc excess be present in the use of one model family whilst being absent from another. A simple comparison of kurucz model spectra with marcs and nextgen model spectra of identical stellar parameters was conduc...

2010-01-01

289

The Role of Home Economics: Population and Family Life Education in Nigeria

Teaching and Learning Guide for: Fairness and Power in Family Organization

Home economics is a dynamic field that imparts knowledge intended to help people adapt to their environment by making effective use of human and material resources. Hence, the profession values global concerns for the environment, human rights, health, and well-being. In Nigeria, home economics teachers must also consider the role they play in programs such as family life education, poverty alleviation, and universal basic education. In particular, home economics is one of the subjects through which core messages of the country's Population and Family Life Education program are to be integrated at the secondary school level. In this article, the author discusses the outcomes of this program and provides recommendations for teachers teaching this subject. (Contains 1 table and 1 resource.)

2004-12-01

290

British Library Electronic Table of Contents (United Kingdom)

This guide accompanies the following article: Gabrielle Poeschl, `What Family Organization Tells Us about Fairness and Power in Marital Relationships', Social and Personality Compass 1/1 (2007): 557-571, 10.1111/j.1751-9004.2007.00026.x Author's Introduction One thing that often strikes me, when I talk with people, is the human capacity to accept and defend surprising aspects of the social life. Thus, we have some feeling that the separation between the domestic and the public spheres has not always existed, but we are ready to assume that in the first human groups, men went out hunting to feed their family, while women stayed in the camp to take care of the children. Even in the face of evidence to the contrary, we are reluctant to question the opinion that men and women differ in persona...

2009-01-01

291

String Universality in Six Dimensions

Generalized Linear Models in Family Studies

In six dimensions, cancellation of gauge, gravitational, and mixed anomalies strongly constrains the set of quantum field theories which can be coupled consistently to gravity. We show that for some classes of six-dimensional supersymmetric gauge theories coupled to gravity, the anomaly cancellation conditions are equivalent to tadpole cancellation and other constraints on the matter content of heterotic/type I compactifications on K3. In these cases, all consistent 6D supergravity theories have a realization in string theory. We find one example which may arise from a novel string compactification, and we identify a new infinite family of models satisfying anomaly factorization. We find, however, that this infinite family of models, as well as other infinite families of models previously identified by Schwarz are pathological. We suggest that it may be feasible to demonstrate that there is a string theoretic realization of ...

2009-01-01

292

Distinguishing two groups of flavin reductases by analyzing the protonation state of an active site carboxylic acid

Generalized linear models (GLMs), as defined by J. A. Nelder and R. W. M. Wedderburn (1972), unify a class of regression models for categorical, discrete, and continuous response variables. As an extension of classical linear models, GLMs provide a common body of theory and methodology for some seemingly unrelated models and procedures, such as the logistic, Poisson, and probit models, that are increasingly used in family studies. This article provides an overview of the principle and the key components of GLMs, such as the exponential family of distributions, the linear predictor, and the link function. To illustrate the application of GLMs, this article uses Canadian national survey data to build an example focusing on the number of close friends among older adults. The article concludes with a discussion of the strengths and weaknesses of GLMs.

2005-11-01

293

British Library Electronic Table of Contents (United Kingdom)

Abstract Flavin-containing reductases are involved in a wide variety of physiological reactions such as photosynthesis, nitric oxide synthesis, and detoxification of foreign compounds, including therapeutic drugs. Ferredoxin-NADP(H)-reductase (FNR) is the prototypical enzyme of this family. The fold of this protein is highly conserved and occurs as one domain of several multidomain enzymes such as the members of the diflavin reductase family. The enzymes of this family have emerged as fusion of a FNR and a flavodoxin. Although the active sites of these enzymes are very similar, different enzymes function in opposite directions, that is, some reduce oxidized nicotinamide adenine dinucleotide phosphate (NADP+) and some oxidize reduced nicotinamide adenine dinucleotide phosphate (NADPH). In t...

2011-01-01

294

Cytoplasmic p63 immunohistochemistry is a useful marker for muscle differentiation: an immunohistochemical and immunoelectron microscopic study

British Library Electronic Table of Contents (United Kingdom)

TP63, a member of the TP53 gene family, is a nuclear marker of myoepithelial cells. Antibody against p63 is frequently used to aid in the diagnosis of prostate carcinoma, as well as in the identification of myoepithelial cells in other tissues including the breast. p63 is also a marker for squamous cell carcinoma. Recently, it was found that all p53 family members are involved in regulating the process of muscle differentiation through the retinoblastoma (RB) protein. Ablation of these p53 family functions blocks the differentiation program and promotes malignant transformation by enabling cooperating oncogenes to transform myoblasts. We therefore studied p63 expression in a number of neoplasms with myogenic differentiation. Immunohistochemical staining for p63 was performed on paraffin se...

2011-01-01

295

Construction cost impact analysis of the U.S. Department of Energy mandatory performance standards for new federal commercial and multi-family, high-rise residential buildings

Comparative biochemistry of betaine biosynthesis and accumulation in diverse dicot families

In accordance with federal legislation, the U.S. Department of Energy (DOE) has conducted a project to demonstrate use of its Energy Conservation Voluntary Performance Standards for Commercial and Multi-Family High-Rise Residential Buildings; Mandatory for New Federal Buildings; Interim Rule (referred to in this report as DOE-1993). A key requisite of the legislation requires DOE to develop commercial building energy standards that are cost effective. During the demonstration project, DOE specifically addressed this issue by assessing the impacts of the standards on (1) construction costs, (2) builders (and especially small builders) of multi-family, high-rise buildings, and (3) the ability of low-to moderate-income persons to purchase or rent units in such buildings. This document reports on this project.

1993-12-01

296

A partnership approach to service needs assessment with family caregivers of an aging relative living at home: A qualitative analysis of the experiences of caregivers and practitioners

Salt stress elicits betaine accumulation to high levels in species from several diverse dicot families (Chenopodiaceae, Amaranthaceae, Convolvulaceae, Solanaceae, and Asteraceae). FAM-MS studies with deuterated precursors showed that species from all these families synthesize betaine from choline. Enzyme assays and immunotitration data showed that all accumulating species contained betaine aldehyde dehydrogenase (BADH) enzyme activity recognized by antibodies raised against purified BADH isolated from Spinacia oleracea. Immunoblotting indicated that the BADH monomer was in all cases of Mr {approx} 63,000. The similarity of BADH in the different species is consistent with a single evolutionary origin for the betaine pathway. This was supported by the presence in immunoblots of a cross-reacting band at Mr {approx} 63,000 in Magnolia x Soulangiana, a primitive angiosperm.

1989-04-01

297

British Library Electronic Table of Contents (United Kingdom)

Background: As the global population ages, support for family caregivers who provide the bulk of care to community-dwelling older people is becoming ever more important. However, in many countries, homecare-service practitioners currently do not follow a systematic approach to assessing and responding to caregiver needs. Objectives: The aim of this study was to explore the experiences of caregivers and practitioners who took part in a field test of the Family Caregivers Support Agreement (FCSA) tool, a modified version of the Carers Outcome Agreement Tool (COAT) initially developed as the result of an Anglo-Swedish study. Both the COAT and the FCSA are designed to facilitate partnerships between caregivers and practitioners so that needs assessment and subsequent support services are negot...

2010-01-01

298

flhDC, the Flagellar Master Operon of Xenorhabdus nematophilus: Requirement for Motility, Lipolysis, Extracellular Hemolysis, and Full Virulence in Insects

Women's autonomy in household decision-making: a demographic study in Nepal

Xenorhabdus is a major insect pathogen symbiotically associated with nematodes of the family Steinernematidae. This motile bacterium displays swarming behavior on suitable media, but...Full Text Available

2000-01-01

299

Wnt3a Induces Myofibroblast Differentiation by Upregulating TGF-? Signaling Through SMAD2 in a ?-Catenin-Dependent Manner

BackgroundHow socio-demographic factors influence women's autonomy in decision making on health care including purchasing goods and visiting family and relatives are very poorly...Full Text Available

300

Which Circulating Antioxidant Vitamins Are Confounded by Socioeconomic Deprivation? The MIDSPAN Family Study

Growing evidence suggests the Wnt family of secreted glycoproteins and their associated signaling pathways, linked to development, are recapitulated during wound repair and regeneration events. However,...Full Text Available

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301

Urinary tract infection in children.

BackgroundAntioxidant vitamins are often described as having “independent” associations with risk of cancer, cardiovascular disease (CVD) and mortality. We aimed...Full Text Available

302

Ultrabiomicroscopic-Histopathologic Correlations in Individuals with Autosomal Dominant Congenital Microcoria: Three-Generation Family Report

During 1968-77, 572 consecutive children with one or more positive urine cultures who were referred by their family doctors to one paediatric surgical outpatient clinic were investigated and prospectively...Full Text Available

1984-08-04

303

The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation

BackgroundCongenital microcoria (CMC) is due to a maldevelopment of the dilator pupillae muscle of the iris, with a pupil diameter of less than 2 mm. It is associated with juvenile...Full Text Available

304

The opiorphin gene (ProL1) and its homologues function in erectile physiology

Purpose of ReviewThe vertebrate cap’n’collar family transcription factor Nrf2 and its invertebrate homologs SKN-1 (in worms) and CncC (in flies) function...Full Text Available

2011-01-01

305

The Potential for pathogenicity was present in the ancestor of the Ascomycete subphylum Pezizomycotina

OBJECTIVETo determine if ProL1, a member of the opiorphin family of genes, can modulate erectile physiology, as it encodes a peptide which acts as...Full Text Available

2008-09-01

306

The Exceptionally Large Genome of Hendra Virus: Support for Creation of a New Genus within the Family Paramyxoviridae

BackgroundPrevious studies in Ascomycetes have shown that the function of gene families of which the size is considerably larger in extant pathogens than in non-pathogens could be...Full Text Available

307

The Anopheles gambiae glutathione transferase supergene family: annotation, phylogeny and expression profiles

An outbreak of acute respiratory disease in Hendra, a suburb of Brisbane, Australia, in September 1994 resulted in the deaths of 14 racing horses and a horse trainer. The causative agent was a new member...Full Text Available

2000-11-01

308

Temporal trends in hepatitis B and C infection in family blood donors from interior Sindh, Pakistan

BackgroundTwenty-eight genes putatively encoding cytosolic glutathione transferases have been identified in the Anopheles gambiae genome. We manually annotated these...Full Text Available

309

Temporal and Tissue-Specific Patterns of Pon3 Expression in Mouse: In situ Hybridization Analysis

BackgroundHepatitis B (HBV) and C (HCV) infections are a serious global and national public health problem. Earlier studies have reported increasing rates of hepatitis infection...Full Text Available

310

Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain

PON3 is a member of the paraoxonase gene family that includes PON1 and PON2. For example, PON3 and PON1 share...Full Text Available

2010-01-01

311

Synergistic Operation of the CAR2 (Ornithine Transaminase) Promoter Elements in Saccharomyces cerevisiae

SummaryTRPV1 is the founding and best-studied member of the family of temperature-activated transient receptor potential ion channels (thermoTRPs). Voltage, chemicals, and heat...Full Text Available

2010-06-01

312

Sugarcane pests and their management

Dal82p binds to the UIS_ALL sites of allophanate-induced genes of the allantoin-degradative pathway and functions synergistically with the GATA family Gln3p and Gat1p transcriptional...Full Text Available

1999-11-01

313

Structural Characterization and Expression Analysis of the SERK/SERL Gene Family in Rice (Oryza sativa)

This book chapter discusses sugarcane culture and history, describes arthropod biologies and injury, and identifies sugarcane pest management factors to consider for people interested in commercial sugarcane production. Arthropod groups include 10 orders and 40 families. Sugarcane pest management ...

314

Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain*

Somatic embryogenesis (SE) is the developmental restructuring of somatic cells towards the embryogenic pathway and forms the basis of cellular totipotency in angiosperms. With the availability of full-length...Full Text Available

2009-01-01

315

Sequence and expression of the zebrafish alpha-actinin gene family reveals conservation and diversification among vertebrates

Recognition of acetylated chromatin by the bromodomains and extra-terminal domain (BET) family proteins is a hallmark for transcriptional activation and anchoring viral genomes to mitotic chromosomes...Full Text Available

2010-03-05

316

Safety Nets and Scaffolds: Parental Support in the Transition to Adulthood

alpha-actinins are actin microfilament crosslinking proteins. Vertebrate actinins fall into two classes: the broadly-expressed actinins 1 and 4 (actn1 and actn4)...Full Text Available

2009-11-01

317

Role of serum carrier proteins in the peripheral metabolism and tissue distribution of thyroid hormones in familial dysalbuminemic hyperthyroxinemia and congenital elevation of thyroxine-binding globulin.

Using longitudinal data from the Youth Development Study (analytic sample N = 712), we investigate how age, adult role acquisition and attainments, family resources, parent-child relationship...Full Text Available

2011-04-01

318

Reversal of Depressed Behaviors by p11 Gene Therapy in the Nucleus Accumbens

To investigate the role of thyroxine-binding globulin (TBG) and albumin in the availability of thyroid hormones to peripheral tissues, comprehensive kinetic studies of thyroxine (T4) and triiodothyronine...Full Text Available

1987-08-01

319

Retinoic acid X receptor in the diploblast, Tripedalia cystophora

The etiology of major depression remains unknown, but dysfunction of serotonergic signaling has long been implicated in the pathophysiology of this disorder. p11 is an S100 family member recently...Full Text Available

2010-10-20

320

Psychosocial Characteristics of Optimum Performance in Isolated ...

Nuclear hormone receptors comprise a characteristic family of transcription factors found in vertebrates, insects and nematodes. Here we show by cDNA and gene cloning that a Cnidarian, Tripedalia...Full Text Available

1998-11-10

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

321

Prenatal diagnosis for recessive dystrophic epidermolysis bullosa in 10 families by mutation and haplotype analysis in the type VII collagen gene (COL7A1).

Studies were assigned values based on whether they were anecdotal or ... or family income), work experience, birth order, military or civilian ...... observed with submarine personnel and polar expeditioners (Sandal et al., 1996). ...

322

Polymorphisms associated with type 2 diabetes in familial longevity: The Leiden Longevity Study

BACKGROUND: Epidermolysis bullosa (EB) is a group of heritable diseases that manifest as blistering and erosions of the skin and mucous membranes. In the dystrophic forms of EB (DEB), the diagnostic...Full Text Available

1996-01-01

323

Physiologic aspects of continence after colectomy, mucosal proctectomy, and endorectal ileo-anal anastomosis.

Human longevity is in part genetically determined, and the insulin/IGF-1 signal transduction (IIS) pathway has consistently been implicated. In humans, type 2 diabetes is a frequent disease that results...Full Text Available

324

Persistent Staphylococcus aureus Colonization Is Not a Strongly Heritable Trait in Amish Families

We examined the physiology of continence in 12 patients at least four months after colectomy, mucosal proctectomy, and endorectal ileo-anal anastomosis for ulcerative colitis and familial polyposis....Full Text Available

1982-04-01

325

Paediatric Palliative Care: Theory to Practice

About 20% of adults are persistently colonized with S. aureus in the anterior nares. Host genetic factors could contribute susceptibility to this phenotype. The objective of...Full Text Available

326

Overweight and obesity among school-going children of Lucknow city

Paediatric palliative care is a holistic approach aimed at addressing the complex issues related to the care of children and families facing chronic life limiting illnesses. The needs of children are...Full Text Available

2011-01-01

327

Orp1, a member of the Cdc18/Cdc6 family of S-phase regulators, is homologous to a component of the origin recognition complex.

Background:Childhood obesity is increasingly being observed with changing lifestyles of families. The magnitude of overweight ranges from 9% to 27.5% and obesity ranges...Full Text Available

2011-05-01

328

On the Austral-Antarctic stenothoids Proboloides, Metopoides, Torometopa and Scaphodactylus (Crustacea Amphipoda) Part 2: the genus Proboloides, with description of two new genera and the transfer of two nominal species to Metopoides

cdc18+ of Schizosaccharomyces pombe is a periodically expressed gene that is required for entry into S phase and for the coordination of S phase with mitosis. cdc18+ is related to the Saccharomyces...Full Text Available

1995-12-19

329

Novel Analogs and Stereoisomers of the Marine Toxin Neodysiherbaine with Specificity for Kainate Receptors

AbstractThis is the second part of a revision of the most plesiomorphic genera in the amphipod family Stenothoidae sensu lato...Full Text Available

330

Mutation analysis of 272 Spanish families affected by autosomal recessive retinitis pigmentosa using a genotyping microarray

Antagonists for kainate receptors (KARs), a family of glutamate-gated ion channels, are efficacious in a number of animal models of neuropathologies, including epilepsy, migraine pain, and anxiety....Full Text Available

2008-02-01

331

Modulation of Expression of the ToxR Regulon in Vibrio cholerae by a Member of the Two-Component Family of Response Regulators

PurposeRetinitis pigmentosa (RP) is a genetically heterogeneous disorder characterized by progressive loss of vision. The aim of this study was to identify the causative mutations...Full Text Available

332

The ToxRS system in Vibrio cholerae plays a central role in the modulation of virulence gene expression in response to environmental stimuli. An integration of multiple signalling inputs...Full Text Available

1998-12-01

333

Meson spectrum

Mammalian Sirt1: insights on its biological functions

Using the Klein-Gordon equation with a box potential, a mass formula describing the family of nonflavored meson states with I = 1 is derived. The energy levels calculated agree with those observed within an accuracy of approx. 5%. In the model discussed quarks behave like tachyons.

1987-12-01

334

Low level of polymorphism in two putative NPR1 homologs in the Vitaceae family

Sirt1 (member of the sirtuin family) is a nicotinamide adenosine dinucleotide (NAD)-dependent deacetylase that removes acetyl groups from various proteins. Sirt1 performs a wide variety of functions...Full Text Available

335

Localization of Reversion-Induced LIM Protein (RIL) in the Rat Central Nervous System

BackgroundGrapevine is subjected to numerous pests and diseases resulting in the use of phytochemicals in large quantities. The will to decrease the use of phytochemicals leads to...Full Text Available

336

Lizards in the ecology of salmonellosis in Panama.

Reversion-induced LIM protein (RIL) is a member of the ALP (actinin-associated LIM protein) subfamily of the PDZ/LIM protein family. RIL serves as an adaptor protein and seems to regulate cytoskeletons....Full Text Available

2009-02-28

337

Ixodes scapularis tick serine proteinase inhibitor (serpin) gene family; annotation and transcriptional analysis

Enteropathogenic bacteria was isolated from 131 of 447 (29.4%) neotropical Panamanian lizards belonging to 34 species of seven families. Overall, 147 strains of bacteria were isolated comprising 26...Full Text Available

1981-05-01

338

Involvement of the chemokine-like receptor GPR33 in innate immunity?

BackgroundSerine proteinase inhibitors (Serpins) are a large superfamily of structurally related, but functionally diverse proteins that control essential proteolytic pathways in...Full Text Available

339

Insect juvenile hormone resistance gene homology with the bHLH-PAS family of transcriptional regulators

Chemokine receptors control leukocyte chemotaxis and cell-cell communication but have also been associated with pathogen entry. GPR33, an orphan member of the chemokine-like receptor family,...Full Text Available

2010-05-28

340

Infinite bubbling in non-K\\"ahlerian geometry

Juvenile hormone analog (JHA) insecticides are relatively nontoxic to vertebrates and offer effective control of certain insect pests. Recent reports of resistance in whiteflies and mosquitoes demonstrate...Full Text Available

1998-03-17

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

341

If I Had - A Family History of Heart Disease

In a holomorphic family $(X_b)_{b\\in B}$ of non-K\\"ahlerian compact manifolds, the holomorphic curves representing a fixed 2-homology class do not form a proper family in general. The deep source of this fundamental difficulty in non-K\\"ahler geometry is the {\\it explosion of the area} phenomenon: the area of a curve $C_b\\subset X_b$ in a fixed 2-homology class can diverge as $b\\to b_0$. This phenomenon occurs frequently in the deformation theory of class VII surfaces. For instance it is well known that any minimal GSS surface $X_0$ is a degeneration of a 1-parameter family of simply blown up primary Hopf surfaces $(X_z)_{z\\in D\\setminus\\{0\\}}$, so one obtains non-proper families of exceptional divisors $E_z\\subset X_z$ whose area diverge as $z\\to 0$. Our main goal is to study in detail this non-properness phenomenon in the case of class VII surfaces. We will prove that, under certain ...

2010-01-01

342

Identification of genetic variation and haplotype structure of the canine ABCA4 gene for retinal disease association studies

... Hospital & University Hospital Basel) If I Had - Pre-diabetes - Dr. Venkat Narayan, MD, MSc, MBA, Rollins School ... School, Massachusetts General Hospital, Discusses the Treatment of Diabetes Back to Home Page If I Had - A ...

343

Identification of Host Proteins Associated with Retroviral Vector Particles by Proteomic Analysis of Highly Purified Vector Preparations?

Over 200 mutations in the retina specific member of the ATP-binding cassette transporter super-family (ABCA4) have been associated with a diverse group of human retinal diseases....Full Text Available

2010-10-01

344

Hysteretic Behavior of Proprotein Convertase 1/3 (PC1/3)

The Moloney murine leukemia virus (MMLV) belongs to the Retroviridae family of enveloped viruses, which is known to acquire minute amounts of host cellular proteins both on the surface...Full Text Available

2008-02-01

345

Hsp12.6 Expression Is Inducible by Host Immunity in Adult Worms of the Parasitic Nematode Nippostrongylus brasiliensis

The proprotein convertases (PCs) are calcium-dependent proteases responsible for processing precursor proteins into their active forms in eukariotes. The PC1/3 is a pivotal enzyme of this family that...Full Text Available

346

Generation of microsatellite repeat families by RTE retrotransposons in lepidopteran genomes

Heat shock proteins (Hsp) are a family of stress-inducible molecular chaperones that play multiple roles in a wide variety of animals. However, the roles of Hsps in parasitic nematodes remain largely...Full Text Available

347

Generation of a BAC-based physical map of the melon genome

BackgroundDeveloping lepidopteran microsatellite DNA markers can be problematical, as markers often exhibit multiple banding patterns and high frequencies of non-amplifying "null"...Full Text Available

348

Functional and Structural Analysis of a Key Region of the Cell Wall Inhibitor Moenomycin

BackgroundCucumis melo (melon) belongs to the Cucurbitaceae family, whose economic importance among horticulture crops is second only to Solanaceae. Melon has high...Full Text Available

349

Functional Interactions between Retinoblastoma and c-MYC in a Mouse Model of Hepatocellular Carcinoma

Moenomycin A (MmA) belongs to a family of natural products that inhibit peptidoglycan biosynthesis by binding to the peptidoglycan glycosyltransferases (PGTs), the enzymes that make the glycan...Full Text Available

2010-07-16

350

Family Gauge Symmetry as an Origin of Koide's Mass Formula and Charged Lepton Spectrum

Inactivation of the RB tumor suppressor and activation of the MYC family of oncogenes are frequent events in a large spectrum of human cancers. Loss of RB function and MYC activation are thought to...Full Text Available

351

Familial premature ovarian failure.

Koide's mass formula is an empirical relation among the charged lepton masses which holds with a striking precision. We present a model of charged lepton sector based on U(3)\\times SU(2) family gauge symmetry, which predicts Koide's formula within the present experimental accuracy. Radiative corrections as well as other corrections to Koide's mass formula are kept under control. We adopt a known mechanism, through which the charged lepton spectrum is determined by the vacuum expectation value of a 9-component scalar field \\Phi. On the basis of this mechanism, we implement the following mechanisms into our model: (1) The radiative correction induced by family gauge interaction cancels the QED radiative correction to Koide's mass formula, assuming a scenario in which the U(3) family gauge symmetry and SU(2)_L weak gauge symmetry are unified at 10^2-10^3 TeV scale; (2) A simple potential of \\Phi invariant under U(3)\\times ...

2009-01-01

352

Expression profiles of precursor and mature microRNAs under dehydration and high salinity shock in Populus euphratica

Premature menopause, ovarian failure younger than 40 years of age, is relatively rare but may preclude childbearing for some women who delay attempts at fertility. We present five kindreds in which...Full Text Available

1984-11-01

353

British Library Electronic Table of Contents (United Kingdom)

MicroRNAs (miRNAs) are small non-coding RNAs that play vital roles in plant abiotic stress responses via cleavage or translational inhibition of their target mRNAs. Populus euphratica is a typical stress-resistant sessile organism that grows in desert areas. Here, we identified sequences of 12 miRNA precursors from 11 families and 13 mature miRNAs from 12 families by PCR amplification in P. euphratica. To detect expression differences in mature miRNAs and their precursors under dehydration and high salinity shock in P. euphratica, we examined 14 miRNA precursors from 13 miRNA families and 17 mature miRNAs from 17 miRNA families using the SYBR Green RT?PCR assay. This is the first report of expression profiles for both precursor and mature miRNAs in P. euphratica. By profiling both the matu...

2011-01-01

354

Expression of leukotriene receptors in the rat dorsal root ganglion and the effects on pain behaviors

Expression of CD1d in human scalp skin and hair follicles: hair cycle related alterations

BackgroundLeukotrienes (LTs) belong to the large family of lipid mediators implicated in various inflammatory conditions such as asthma and rheumatoid arthritis. Four distinct types...Full Text Available

355

Expression and Characterization of the Mycobacterium tuberculosis Serine/Threonine Protein Kinase PknB

Background: CD1d belongs to a family of antigen presenting molecules that are structurally and distantly related to the classic major histocompatibility complex class I (MHC I)...Full Text Available

2005-12-01

356

Evolution of the nuclear ribosomal DNA intergenic spacer in four species of the Daphnia pulex complex

PknB is a member of the newly discovered eukaryotic-like protein serine/threonine kinase (PSTK) family of proteins. The pknB gene was cloned and expressed in Escherichia coli....Full Text Available

1999-11-01

357

Evidence of linkage disequilibrium in the Spanish polycystic kidney disease I population.

BackgroundConcerted evolution refers to the pattern in which copies of multigene families show high intraspecific sequence homogeneity but high interspecific sequence diversity....Full Text Available

358

Evidence for proteolytic cleavage of brevican by the ADAMTSs in the dentate gyrus after excitotoxic lesion of the mouse entorhinal cortex

Forty-one Spanish families with polycystic kidney disease 1 (PKD1) were studied for evidence of linkage disequilibrium between the disease locus and six closely linked markers. Four of these loci--three...Full Text Available

1994-05-01

359

Empirically Defined Subtypes of Alcohol Dependence in an Irish Family Sample

BackgroundBrevican is a member of the lectican family of aggregating extracellular matrix (ECM) proteoglycans that bear chondroitin sulfate (CS) chains. It is highly expressed in...Full Text Available

360

Emergence of Switch-Like Behavior in a Large Family of Simple Biochemical Networks

Alcohol dependence (AD) is clinically and etiologically heterogeneous. The goal of this study was to explore AD subtypes among a sample of 1, 221 participants in the Irish Affected Sib Pair...Full Text Available

2010-03-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

361

Effects of hyperbilirubinaemia on glutathione S-transferase isoenzymes in cerebellar cortex of the Gunn rat.

Bistability plays a central role in the gene regulatory networks (GRNs) controlling many essential biological functions, including cellular differentiation and cell cycle control. However, establishing...Full Text Available

2011-05-01

362

Effects of PKA phosphorylation on the conformation of the Na,K-ATPase regulatory protein FXYD1

The glutathione S-transferases (GSTs) are a family of isoenzymes involved in the detoxication of a variety of electrophilic xenobiotics. The present investigation demonstrates that GST activity and...Full Text Available

1993-04-15

363

Effects of Cynodon dactylon on Stress-Induced Infertility in Male Rats

FXYD1 (phospholemman) is a member of an evolutionarily conserved family of membrane proteins that regulate the function of the Na,K-ATPase enzyme complex in specific tissues and specific physiological...Full Text Available

2009-11-01

364

Ectopic Expression of Constitutively Activated RACB in Barley Enhances Susceptibility to Powdery Mildew and Abiotic Stress1

Cynodon dactylon (Family: Poaceae) is known to be a tackler in Indian mythology and is offered to Lord Ganesha. It is found everywhere, even on waste land, road side, dry places, and...Full Text Available

2011-01-01

365

Drosophila melanogaster Methoprene-tolerant (Met) gene homologs from three mosquito species: members of PAS transcriptional factor family

Small RAC/ROP-family G proteins regulate development and stress responses in plants. Transient overexpression and RNA interference experiments suggested that the barley (Hordeum vulgare)...Full Text Available

2005-09-01

366

Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer

The Methoprene-tolerant (Met) gene in Drosophila melanogaster has been shown to function in juvenile hormone (JH) action. Met...Full Text Available

2007-03-01

367

Correlation of Pain Scores, Analgesic Use, and Beck Anxiety Inventory Scores During Hospitalization in Lower Extremity Amputees

The p21-activated kinases (PAKs), immediate downstream effectors of the small G-proteins of the Rac/cdc42 family, are critical mediators of signaling pathways regulating cellular behaviors and...Full Text Available

2010-09-01

368

Common Familial Colorectal Cancer Linked to Chromosome 7q31: a genome-wide analysis

Post amputation pain can be debilitating for patients and families. Chronic pain is a common phenomenon after lower extremity amputation, occurring in up to 80% of this population. The purpose of this...Full Text Available

369

Collective trauma in northern Sri Lanka: a qualitative psychosocial-ecological study

Present investigations suggest that approximately 30% of colorectal cancer (CRC) cases arise on the basis of inherited factors. We hypothesize that the majority of inherited factors are moderately...Full Text Available

2008-11-01

370

Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV.

BackgroundComplex situations that follow war and natural disasters have a psychosocial impact on not only the individual but also on the family, community and society. Just as the...Full Text Available

371

Chiropteran types I and II interferon genes inferred from genome sequencing traces by a statistical gene-family assembler

The cellular receptor for murine coronavirus mouse hepatitis virus (MHV)-A59 is a member of the carcinoembryonic antigen (CEA) family of glycoproteins in the immunoglobulin superfamily. We isolated...Full Text Available

1991-12-01

372

Characterization, phylogeny, alternative splicing and expression of Sox30 gene

BackgroundThe rate of emergence of human pathogens is steadily increasing; most of these novel agents originate in wildlife. Bats, remarkably, are the natural reservoirs of many...Full Text Available

373

Characterization of the functional gene and several processed pseudogenes in the human triosephosphate isomerase gene family.

BackgroundMembers of the Sox gene family isolated from both vertebrates and invertebrates have been proved to participate in a wide variety of developmental processes, including...Full Text Available

374

Chapter 2, A Quick-look at your Pay - NASAPeople

The functional gene and three intronless pseudogenes for human triosephosphate isomerase were isolated from a recombinant DNA library and characterized in detail. The functional gene spans 3.5 kilobase...Full Text Available

1985-07-01

375

Cardiac Myosin Is a Substrate for Zipper-interacting Protein Kinase (ZIPK)*

You receive an annuity if eligible -- requires 18 months service for FERS; and 60 ... You may use up to 104 hours of your accrued sick leave to care for sick family ...

376

Cadherin Mechanics and Complexation: The Importance of Calcium Binding

Zipper-interacting protein kinase (ZIPK) is a member of the death-associated protein kinase family associated with apoptosis in nonmuscle cells where it phosphorylates myosin regulatory light chain...Full Text Available

2010-02-19

377

Biotransformation of Explosives by the Old Yellow Enzyme Family of Flavoproteins

E-cadherins belong to a family of membrane-bound, cellular adhesion proteins. Their adhesive properties mainly involve the two N-terminal extracellular domains (EC1 and EC2). The junctions between these...Full Text Available

2005-12-01

378

Biogeography of Tick-Borne Bhanja Virus (Bunyaviridae) in Europe

Several independent studies of bacterial degradation of nitrate ester explosives have demonstrated the involvement of flavin-dependent oxidoreductases related to the old yellow enzyme (OYE) of yeast....Full Text Available

2004-06-01

379

Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells

Bhanja virus (BHAV) is pathogenic for young domestic ruminants and also for humans, causing fever and affections of the central nervous system. This generally neglected arbovirus of the family Bunyaviridae...Full Text Available

2009-01-01

380

Avian Nephritis Virus (ANV) as a New Member of the Family Astroviridae and Construction of Infectious ANV cDNA

The CD1 family of proteins binds self and foreign glycolipids for presentation to CD1-restricted T cells. To identify previously uncharacterized active CD1 ligands, especially those of microbial origin,...Full Text Available

2005-02-01

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381

Autoantibodies to BRAF, a new family of autoantibodies associated with rheumatoid arthritis

The complete RNA genome of the avian nephritis virus (ANV) associated with acute nephritis in chickens has been molecularly cloned and sequenced. Excluding the poly(A) tail, the genome comprises 6,927...Full Text Available

2000-09-01

382

Assessing the Significance of Above- and Belowground Carbon Allocation of Fast- and Slow-Growing Families of Loblolly Pine - Final Report

IntroductionBRAF (v raf murine sarcoma viral oncogene homologue B1) is a serine-threonine kinase involved in the mitogen-activated protein kinase (MAPK) signalling pathway, known...Full Text Available

2010-01-01

383

Apolipoprotein E-Mimetics Inhibit Neurodegeneration and Restore Cognitive Functions in a Transgenic Drosophila Model of Alzheimer's Disease

During this project we experimentally evaluated the below-ground biomass and carbon allocation and partitioning of four different fast- and slow-growing families of loblolly pine located in Scotland County, NC, in an effort to increase the long-term performance of the crop. The trees were subjected to optimal nutrition and control since planting in 1993. Destructive harvests in 1998 and 2000 were used for whole?plant biomass estimates and to identify possible family differences in carbon acquisition (photosynthesis) and water use efficiency. At regular intervals throughout each year we sampled tissues for carbohydrate analyses to assess differences in whole-tree carbon storage. Mini rhizotron observation tubes were installed to monitor root system production and turnover. Stable isotope analysis was used to examine possible functional differences in water and nutrient acquisition of root systems between the various ...

2001-03-01

384

Ammonium and Nitrate Uptake by the Floating Plant Landoltia punctata

BackgroundMutations of the amyloid precursor protein gene (APP) are found in familial forms of Alzheimer's disease (AD) and some lead to the elevated production...Full Text Available

385

A wide spectrum of clinical and brain MRI findings in patients with SLC19A3 mutations

Background and AimsPlants from the family Lemnaceae are widely used in ecological engineering projects to purify wastewater and eutrophic water bodies. However, the biology of nutrient...Full Text Available

2007-02-01

386

A new perspective on phylogeny and evolution of tetraodontiform fishes (Pisces: Acanthopterygii) based on whole mitochondrial genome sequences: Basal ecological diversification?

BackgroundSLC19A3 (solute carrier family 19, member 3) is a thiamin transporter with 12 transmembrane domains. Homozygous or compound heterozygous mutations in SLC19A3 cause...Full Text Available

387

A modular approach to DC to DC power converters

BackgroundThe order Tetraodontiformes consists of approximately 429 species of fishes in nine families. Members of the order exhibit striking morphological diversity and radiated...Full Text Available

388

A Patient Survey Assessing the Awareness and Acceptability of the Emergency Care Summary and Its Consent Model in Scotland

A familiar power inverter circuit, combined with a ferroresonant transformer and a simple control circuit, provides the basis for an economically attractive modular family of DC to DC converters. The circuit is readily adaptable to a wide range of input voltages and single or multiple output voltages.

1974-01-01

389

Tests of New Family Gauge Symmetry

BackgroundThe Emergency Care Summary (ECS) was introduced in 2006 to allow aspects of the general practitioner (GP; family doctor, equivalent to primary care physician) medical record...Full Text Available

390

Modular symmetry in parametrically excited quantum oscillators

We explore the structure of a new family gauge symmetry U(3) and show its experimental signatures to search for. U(3) gauge bosons obviate an unwelcome deviation of the charged lepton mass formula with the running masses from that with the pole masses. The current structure of this model leads to flavor number violations via exchange of extra gauge bosons. We obtain bounds on the masses of the gauge bosons from rare kaon decay searches and muonium-antimuonium oscillation searches. We propose attractive signatures at LHC and lepton colliders and discuss feasibility of their discovery.

2010-01-01

391

Glocalisation or globalisation? Travelling discourses of child poverty policy in South Korea

It is shown that when a quantum mechanical oscillator is parametrically excited there are special values of the parameters for which the system will pass periodically through a lattice of coherent states associated with the modular group [Gamma]. It is shown that these [Gamma] transits can be used to determine unknown parameters. A method is given for detecting the transits experimentally and is made possible by the existence of three families of states associated with modular forms that are orthogonal to the lattice. For isotropic states the three families occur in [ital D]-mode systems with [ital D][gt]10, 14, and 26.

1993-11-29

392

British Library Electronic Table of Contents (United Kingdom)

This article examines the interplay between globalising and localising forces occurring in a child welfare reform project in South Korea. Focusing especially on care and education services for children and families provided by the Korean 'Dream Start' programme, which provides comprehensive health, parental involvement and welfare services to low-income children and their families, I discuss its involvement in the process of 'glocalisation'. Drawing on Foucaultian ideas, I conducted a critical discourse analysis of the policy documents of Dream Start. The article concludes by discussing local resistance to the creation of a cosmopolitan child and the dual qualities of inclusion/exclusion inscribed in the Dream Start project.

2011-01-01

393

Asset Prices, Liquidity, and Monetary Policy in an Exchange Economy

British Library Electronic Table of Contents (United Kingdom)

I formulate a model in which money coexists with equity shares on a risky aggregate endowment. Agents can use equity as a means of payment, so shocks to equity prices translate into aggregate liquidity shocks that disrupt the mechanism of exchange. I characterize a family of optimal monetary policies and find that the resulting equity prices are independent of monetary considerations. I also study a perturbation of the family of optimal policies that targets a positive constant nominal interest rate and find that in this case the real equity return includes a liquidity return that depends on monetary considerations.

2011-01-01

394

Use of platelet glycoprotein IIb/IIIa inhibitors in diabetics undergoing PCI for non-ST-segment elevation acute coronary syndromes: impact of clinical status and procedural characteristics

The Significance of Clopidogrel Low-Responsiveness on Stent Thrombosis and Cardiac Death Assessed by the Verifynow P₂Y₁₂ Assay in Patients With Acute Coronary Syndrome Within 6 Months After Drug-Eluting Stent Implantation

BackgroundThe most recent ESC guidelines for percutaneous coronary intervention (PCI) recommend the use of glycoprotein IIb/IIIa inhibitors (GPI) in high risk patients with non-ST-segment...Full Text Available

2010-06-01

395

Quick Discrimination of A_delta and C Fiber Mediated Pain Based on Three Verbal Descriptors

Background and ObjectivesClopidogrel resistance or low-responsiveness may be associated with recurrent atherothrombotic events after drug-eluting stent (DES) implantation. We prospectively...Full Text Available

2009-12-01

396

BackgroundA_δ and C fibers are the major pain-conducting nerve fibers, activate only partly the same brain areas, and are differently involved in pain syndromes....Full Text Available

397

Modalidade de morte em mamiferos expostos a irradiacao de corpo inteiro (sindrome aguda da radiacao). (Modes of death in mammals exposed to whole body radiation (acute radiation syndromes)).

BackgroundUsing a transcriptional profiling approach, we recently identified myeloid-related protein-8/14 (MRP-8/14) to be expressed by platelets during acute MI....Full Text Available

2008-01-01

398

False-Positive Results in a Recombinant Severe Acute Respiratory Syndrome-Associated Coronavirus (SARS-CoV) Nucleocapsid-Based Western Blot Assay Were Rectified by the Use of Two Subunits (S1 and S2) of Spike for Detection of Antibody to SARS-CoV

When an animal is exposed to a sufficient amount of radiation, there will be changes in many organs of the body, and as a result of either the effects in one particular organ or the interaction of effects in several organs, the animal as a whole will show...

1990-01-01

399

Ephrin B1 Regulates Bone Marrow Stromal Cell Differentiation and Bone Formation by Influencing TAZ Transactivation via Complex Formation with NHERF1?

To evaluate the reactivity of the recombinant proteins expressed in Escherichia coli strain BL21(DE3), a Western blot assay was performed by using a panel of 78 serum samples obtained,...Full Text Available

2006-03-01

400

Endovascular treatment of intrahepatic inferior vena cava obstruction from malignant hepatocellular tumor thrombus utilizing Luminexx self-expanding nitinol stents

Mutations of ephrin B1 in humans result in craniofrontonasal syndrome. Because little is known of the role and mechanism of action of ephrin B1 in bone, we examined the function of osteoblast-produced...Full Text Available

2010-02-01

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401

Duck Egg-Drop Syndrome Caused by BYD Virus, a New Tembusu-Related Flavivirus

Inferior vena cava (IVC) obstruction is a well-described clinical entity. Most IVC obstructions from malignant neoplasms are a direct result of tumor compression [Oviedo J, Cerda S. Vascular invasion by hepatocellular carcinoma. Arch Pathol Lab Med 2001;125: 454-5; Furui S, Sawada S, et al. Gianturco stent placement in malignant caval obstruction: analysis of factors for predicting the outcome. Radiology 1995;195:147-52; Fletcher WS, Lakin PC, et al. Results of treatment of inferior vena cava syndrome with expandable metallic stents. Arch Surg 1998;133:935-8]. The symptoms of IVC obstruction include progressive ascites, scrotal edema and lower body edema. These constellations of symptoms are described as IVC syndrome and are devastating to a patient with end-stage cancer. We describe a palliative therapy utilizing Luminexx nitinol self-expanding stents to treat intracaval hepatoma thrombus obstructing the IVC. The procedure is rapidly ...

2008-05-15

402

Comparative analysis of the ATRX promoter and 5' regulatory region reveals conserved regulatory elements which are linked to roles in neurodevelopment, alpha-globin regulation and testicular function

Since April 2010, a severe outbreak of duck viral infection, with egg drop, feed uptake decline and ovary-oviduct disease, has spread around the major duck-producing regions in China. A new virus, named...Full Text Available

403

Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias

BackgroundATRX is a tightly-regulated multifunctional protein with crucial roles in mammalian development. Mutations in the ATRX gene cause ATR-X syndrome, an X-linked...Full Text Available

404

Clinical and laboratory experience of vorinostat (suberoylanilide hydroxamic acid) in the treatment of cutaneous T-cell lymphoma

BackgroundGene mutation is an important mechanism of myeloid leukemogenesis. However, the number and combination of gene mutated in myeloid malignancies is still a matter of investigation.MethodsWe...Full Text Available

405

Bilateral adrenocortical carcinoma in a patient with multiple endocrine neoplasia type 1 (MEN1) and a novel mutation in the MEN1 gene

The most common cutaneous T-cell lymphomas (CTCLs) – mycosis fungoides (MF) and Sézary Syndrome – are characterised by the presence of clonally expanded, skin-homing helper-memory...Full Text Available

2006-12-01

406

Associations of major bleeding and myocardial infarction with the incidence and timing of mortality in patients presenting with non-ST-elevation acute coronary syndromes: a risk model from the ACUITY trial

The incidence of adrenal involvement in MEN1 syndrome has been reported between 9 and 45%, while the incidence of adrenocortical carcinoma (ACC) in MEN1 patients has been reported between 2.6 and 6%....Full Text Available

407

ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome

AimsTo evaluate the associations of myocardial infarction (MI) and major bleeding with 1-year mortality. Both MI and major bleeding predict 1-year mortality in patients presenting...Full Text Available

2009-06-01

408

Strikingly different penetrance of LHON in two Chinese families with primary mutation G11778A is independent of mtDNA haplogroup background and secondary mutation G13708A

ATR-X (alpha-thalassemia/mental retardation, X-linked) syndrome is a human congenital disorder that causes severe intellectual disabilities. Mutations in the ATRX gene, which encodes an ATP-dependent chromatin-remodeler, are responsible for the syndrome. Approximately 50% of the missense mutations in affected persons are clustered in a cysteine-rich domain termed ADD (ATRX-DNMT3-DNMT3L, ADD{sub ATRX}), whose function has remained elusive. Here we identify ADD{sub ATRX} as a previously unknown histone H3-binding module, whose binding is promoted by lysine 9 trimethylation (H3K9me3) but inhibited by lysine 4 trimethylation (H3K4me3). The cocrystal structure of ADD{sub ATRX} bound to H3{sub 1-15}K9me3 peptide reveals an atypical composite H3K9me3-binding pocket, which is distinct from the conventional trimethyllysine-binding aromatic cage. Notably, H3K9me3-pocket mutants and ATR-X syndrome mutants are defective in both H3K9me3 ...

2011-07-19

409

Strikingly different penetrance of LHON in two Chinese families with primary mutation G11778A is independent of mtDNA haplogroup background and secondary mutation G13708A

The penetrance of Leber's hereditary optic neuropathy (LHON) in families with primary mitochondrial DNA (mtDNA) mutations is very complex. Matrilineal and nuclear genetic background, as well as environmental factors, have been reported to be involved in different affected pedigrees. Here we describe two large Chinese families that show a striking difference in the penetrance of LHON, in which 53.3% and 15.0% of members were affected (P < 0.02), respectively. Analysis of the complete mtDNA genome of the two families revealed the presence of the primary mutation G11778A and several other variants suggesting the same haplogroup status G2a. The family with higher penetrance contained a previously described secondary mutation G13708A, which presents a polymorphism in normal Chinese samples and does not affect in vivo mitochondrial oxidative metabolism as described in a previous study. ...

2008-08-25

410

Social modeling in the transmission of suicidality.

The penetrance of Leber's hereditary optic neuropathy (LHON) in families with primary mitochondrial DNA (mtDNA) mutations is very complex. Matrilineal and nuclear genetic background, as well as environmental factors, have been reported to be involved in different affected pedigrees. Here we describe two large Chinese families that show a striking difference in the penetrance of LHON, in which 53.3% and 15.0% of members were affected (P < 0.02), respectively. Analysis of the complete mtDNA genome of the two families revealed the presence of the primary mutation G11778A and several other variants suggesting the same haplogroup status G2a. The family with higher penetrance contained a previously described secondary mutation G13708A, which presents a polymorphism in normal Chinese samples and does not affect in vivo mitochondrial oxidative metabolism as described in a previous study. Evolutionary ...

2008-08-25

411

Clinically silent heterotaxy with polysplenia syndrome and IVC azygous continuation draining to SVC: CT findings. Case report

Evidence from twin, adoption, and family studies suggests that there is strong aggregation of suicidal behaviors in some families. By comparison, the role of social modeling through peers has yet to be convincingly established. This paper uses data from four large studies (the WHO/EURO Multicentre Study on Suicidal Behaviour, the WHO/SUPRE-MISS, the CASE study, and the Queensland Suicide Register) to compare the effects of exposure to fatal and nonfatal suicidal behavior in family members and nonfamilial associates on the subsequent suicidal behavior of male and female respondents of different ages. Across all studies, we found that prior suicidal behaviors among respondents' social groups were more important predictors of suicidal behavior in the respondents themselves than previous research had indicated. Community-based suicide attempters in the WHO SUPRE-MISS had higher rates of exposure to prior suicide in nonfamilial ...

2008-01-01

412

Losing weight to save lives: A review of the role of automobile weight and size in traffic fatalities

Patients with heterotaxy syndrome often have complex cardiac and extracardiac anomalies requiring further detailed diagnostic evaluation. They often present severe cardiac failure early in life. Newer radiological modalities in the form of spiral computed tomography (CT) and three-dimensional reconstruction of spiral CT allow clear definition of the anatomy of these anomalies. A 59-year-old woman was diagnosed with polysplenia and multiple anomalies in an abdominal ultrasonography (US) during a control medical examination due to a trivial dietary mistake. She was then referred to our institution for further examination of these anomalies and an additional thoraco-abdominal computed tomography (CT) examination. The patient was totally asymptomatic at the time of admission. There was no significant past history and no abnormal laboratory data. We performed abdominal, pelvic and thoracic CT examinations using Somatom Siemens Emotion scanner. Non-enhanced sections were ...

2007-01-01

413

Innovative Structural and Joining Concepts for Lightweight Design of Heavy Vehicle Systems

Critics of higher fuel economy standards for vehicles have long argued that improving vehicle fuel economy will require reducing vehicle weight, and that would result in an increase in the number of fatalities from vehicle crashes. Several researchers have estimated that an across-the-board reduction of vehicle weight would reduce passenger safety (Evans 1991; Kahane 1997; U.S. GAO 1994). However, little research has been done on the relationship of vehicle size and fatality rates, independent of weight (see, however, Joksch, Massie, and Pichler 1998). In this report we review previous analyses of the relationship of vehicle weight and safety. We do this to study the opportunities to improve fuel economy in a more sophisticated way than across-the-board mass reduction. The aim is to explore improvements in traffic safety by making selected vehicle groups lighter, and retaining or enlarging selected vehicle dimensions. Unfortunately, the effects of size and mass ...

2001-07-01

414

The treatment of chronic pain by epidural spinal cord stimulation--a 15 year follow up; present status.

The extensive research and development effort was initiated by the U.S. Department of Energy (DOE) in 2002 at West Virginia University (WVU) in order to investigate practical ways of reducing the structural weight and increasing the durability of heavy vehicles through the judicious use of lightweight composite materials. While this project was initially focused on specific Metal Matrix Composite (MMC) material, namely Aluminum/Silicon Carbide (Al/SiC) commercially referenced as ''LANXIDE'', the current research effort was expanded from the component level to the system level and from MMC to other composite material systems. Broadening the scope of this research is warranted not only by the structural and economical deficiencies of the ''LANXIDE'' MMC material, but also by the strong coupling that exists between the material and the geometric characteristics of the structure. Such coupling requires a truly ...

2006-09-30

415

Space HVAC engineering 2003. Part 1. An overview; Die Luft- und Klimatechnik 2003. Teil 1. Eine Bestandsaufnahme

Pain is necessary for survival but chronic pain is disabling and causes significant health and economic problems. This study provides an understanding of the future for spinal cord stimulation. Stimulation by means of chronically implanted electrodes, was carried out in 200 patients with pain of varied benign organic etiology. In 177 of them, pain was confined to the failed back syndrome. Most patients were referred by a Pain Management Service. 226 epidural implants were used: 80 unipolar, 59 Resume, 12 bipolar, and 75 quadripolar. Patients were followed for periods of 6 months to 12 years, with a mean follow-up of 44 months. 84 patients (42%) were able to control their pain by stimulation alone, 22 patients (11%) needed occasional analgesic supplements along with their stimulation program. Pain secondary to failed back syndrome, multiple sclerosis, peripheral vascular disease, sympathetic dystrophy and diabetic neuropathy responded favorably. ...

1997-06-01

416

Pathology of tissue loss (white syndrome) in Acropora sp. corals from the Central Pacific.

The development of the space HVAC sector during the past 25 years is reviewed. It is shown how the importance of room climate has increased, as illustrated, e.g., by the concepts of 'thermal comfort', 'comfort', and 'sick building syndrome'. A sequel will be published in the next issue of KK. (orig.) [German] Der folgende Beitrag ist eine Bestandsaufnahme im Hinblick auf technologische Entwicklungen in der Klima- und Lueftungstechnik der letzten 25 Jahre, ein Zeitraum in dem sich einiges veraendert hat. Gleichzeitig wird deutlich, welcher Wandel sich bei der Bedeutung des Raumklimas in Gebaeuden vollzogen hat, indem beispielsweise Begriffe wie ''Behaglichkeit'', ''Komfort'' aber auch ''Sick Building Syndrom'' eine immer groessere Rolle spiel(t)en. Die Fortsetzung in der naechsten ...

2003-03-01

417

Message concerning Severe Acute Respiratory Syndrome ("SARS")

We performed histological examination of 69 samples of Acropora sp. manifesting different types of tissue loss (Acropora White Syndrome-AWS) from Hawaii, Johnston Atoll and American Samoa between 2002 and 2006. Gross lesions of tissue loss were observed and classified as diffuse acute, diffuse subacute, and focal to multifocal acute to subacute. Corals with acute tissue loss manifested microscopic evidence of necrosis sometimes associated with ciliates, helminths, fungi, algae, sponges, or cyanobacteria whereas those with subacute tissue loss manifested mainly wound repair. Gross lesions of AWS have multiple different changes at the microscopic level some of which involve various microorganisms and metazoa. Elucidating this disease will require, among other things, monitoring lesions over time to determine the pathogenesis of AWS and the potential role of tissue-associated microorganisms in the genesis of tissue loss. Attempts to experimentally induce AWS should ...

2011-03-30

418

CERN Multimedia

IMPORTANT REMINDER If you have just come back from one of the regions identified by the WHO as being infected with SARS, it is essential to monitor your state of health for ten days after your return. The syndrome manifests itself in the rapid onset of a high fever combined with respiratory problems (coughing, breathlessness, breathing difficulty). Should these signs appear, you must contact the CERN Medical Service as quickly as possible on number 73802 or 73186 during normal working hours, and the fire brigade at all other times on number 74444, indicating that you have just returned from one of the WHO-identified areas with recent local transmission.China: Beijing, Hong Kong (Special Administrative Region), Guangdong Province, Inner Mongolia, Shanxi Province, Tianjin ProvinceTaiwan:TaipeiMoreover, until further notice the CERN Management requests that all trips to these various regions of the world be reduced to a strict minimum and then only with the consent ...

2003-01-01

419

MR findings of central nervous system involvement in acquired immunodeficiency syndrome patient : a report of two cases

Gender differences in the incidence and prevalence of patellofemoral pain syndrome.

Central nervous system (CNS) manifestations in acquired immunodeficiency syndrome (AIDS) patients are an early and common feature. The spectrum of AIDS-related CNS diseases are encephalitis caused by the human immunodeficiency virus(HIV) itself, opportunistic infection, infarct and malignancy. We experienced two cases of CNS involvement in AIDS and they were serologically diagnosed as HIV encephalitis and CNS toxoplasmosis, respectively. In the case of the HIV encephalitis patient, brain MRI showed a non-enhancing lesion with high signal intensity on T2WI and low signal on T1WI and there was no mass effect on the right frontal lobe, periventricular white matter, splenium of the corpus callosum or bilateral basal ganglia. In the other case of CNS toxoplasmosis, MR showed multiple nodular and rim enhanced mass lesions in the right basal ganglia, thalamus and periventricular white matter, which were of low signal intensity on T1WI and of high intensity on T2WI. We ...

1996-10-01

420

Evaluation of the effectiveness of an antimicrobial air filter to avoid porcine reproductive and respiratory syndrome virus (PRRSV) aerosol transmission, after 16 months of exposure to a commercial swine environmental conditions

The purpose of this investigation was to determine the association between gender and the prevalence and incidence of patellofemoral pain syndrome (PFPS). One thousand five hundred and twenty-five participants from the United States Naval Academy (USNA) were followed for up to 2.5 years for the development of PFPS. Physicians and certified athletic trainers documented the cases of PFPS. PFPS was defined as retropatellar pain during at least two of the following activities: ascending/descending stairs, hopping/jogging, prolonged sitting, kneeling, and squatting, negative findings on examination of knee ligament, menisci, bursa, and synovial plica, and pain on palpation of either the patellar facets or femoral condyles. Poisson and logistic regressions were performed to determine the association between gender and the incidence and prevalence of PFPS, respectively. The incidence rate for PFPS was 22/1000 person-years. Females were 2.23 times (95% CI: 1.19, 4.20) more ...

2010-10-01

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421

Clinical biochemistry of aluminum

The effectiveness of Noveko's antimicrobial filter was evaluated after 16 months of exposure to commercial swine production. The experiment involved the use of a scaled model of a commercial swine facility consisting of 2 small chambers connected by a duct containing the filters. A 5 kg naive pig was placed in the reception chamber for a period of 6 hours after aerosolization with porcine reproductive and respiratory syndrome virus (PRRSV). Blood samples from pigs were collected before and after aerosolization to test for the presence of PRRSV RNA. Only blood samples were tested for PRRSV antibodies by IDEXX 2XR ELISA. None of the 9 pigs tested were found to be infected. The study showed that the technology used to integrate the antimicrobial agent into the filter fibers allows the filter combination to withstand extreme weather and endure commercial swine production for at least 16 months, and can maintain its effectiveness to avoid airborne transmission ...

2010-07-01

422

Assessing the risk of ovarian hyperstimulation syndrome in egg donation: implications for human embryonic stem cell research.

Aluminum toxicity has been implicated in the pathogenesis of a number of clinical disorders in patients with chronic renal failure on long-term intermittent hemodialysis treatment. The predominant disorders have been those involving either bone (osteomalacic dialysis osteodystrophy) or brain (dialysis encephalopathy). In nonuremic patients, an increased brain aluminum concentration has been implicated as a neurotoxic agent in the pathogenesis of Alzheimer's disease and was associated with experimental neurofibrillary degeneration in animals. The brain aluminum concentrations of patients dying with the syndrome of dialysis encephalopathy (dialysis dementia) are significantly higher than in dialyzed patients without the syndrome and in nondialyzed patients. Two potential sources for the increased tissue content of aluminum in patients on hemodialysis have been proposed: (1) intestinal absorption from aluminum containing phosphate-binding ...

1981-05-01

423

A prospective study of 100 roboticallyassisted laparoscopic adrenalectomies

Stem cell research has important implications for medicine. The source of stem cells influences their therapeutic potential, with stem cells derived from early-stage embryos remaining the most versatile. Somatic cell nuclear transfer (SCNT), a source of embryonic stem cells, allows for understandings about disease development and, more importantly, the ability to yield embryonic stem cell lines that are genetically matched to the somatic cell donor. However, SCNT requires women to donate eggs, which involves injection of ovulation-inducing hormones and egg retrieval through laparoscopy or transvaginal needle aspiration. Risks from this procedure are fiercely debated, most notably risk of ovarian hyperstimulation syndrome (OHSS). This review examines risk of OHSS resulting from oocyte donation. We conclude that risk posed by OHSS in egg donation is not significant enough to warrant undue concern, and much of this can be eliminated when proper precautions are taken. ...

2011-09-01

424

British Library Electronic Table of Contents (United Kingdom)

We evaluated robotically assisted laparoscopic adrenalectomy (RLA) in a prospective study of 100 consecutive patients (60 women and 40 men) undergoing unilateral adrenalectomy at the University Hospital. The median age was 59 (24?82) years and BMI 27.6 (17.1?40.9) kg/m2. Preoperative diagnoses were Conn?s syndrome 30%, pheochromocytoma 23%, Cushing syndrome 27% and non-functional tumor 20%. The median tumor size was 53 (10?106) mm. The majority of the 7% of the patients who were converted to open surgery were in the early phase after the introduction of the technique. The BMI of the patients who were converted to open surgery was significantly higher, 31.5 (range 25.3?37.8) compared to, 27.5 (range 17.1?40.9) in patients without conversion (P?=?0.047). The median weight of the tumor was 51...

2011-01-01

425

Structure and magnetic properties of the Al1-xGaxFeO3 family of oxides: A combined experimental and theoretical study

Pollen flora of Pakistan--LXVII: acanthaceae

Magnetic properties of the Al1-xGaxFeO3 family of oxides crystallizing in a non-centrosymmetric space group have been investigated in detail along with structural aspects by employing X-ray and neutron diffraction, Moessbauer spectroscopy and other techniques. The study has revealed the occurrence of several interesting features related to unit cell parameters, site disorder and ionic size. Using first-principles density functional theory based calculations, we have attempted to understand how magnetic ordering and related properties in these oxides depend sensitively on disorder at the cation site. The origin and tendency of cations to disorder and the associated properties are traced to the local structure and ionic sizes. -- Graphical abstract: We have studied both experimentally and theoretically the important role of disorder at the cation site on magnetic and related properties of the Al1-xGaxFeO3 family of oxides crystallizing in a ...

2011-03-01

426

Generalized support varieties for finite group schemes

Pollen morphology of 30 species of the family Acanthaceae belonging to 11 genera has been investigated using light and scanning electron microscope. Acanthaceae is a eurypalynous family. Pollen are usually radially symmetrical, isopolar, sub-prolate to prolate rarely prolate-spheroidal or sub-oblate to oblate-spheroidal, generally tricolporate or heterocolporate rarely colpate or porate. Exine ornamentation varies from medium to coarse reticulate, or often lopho-reticulate with luminae perforated to baculate or scabrate. On the basis of apertural type, exine ornamentation and colpal membrane eight distinct pollen types have been recognized viz., Pollen type-I: Barleria cristata-type, Pollen type-II: Blepharis ciliaris-type, Pollen type-III: Hygrophila polysperma - type, Pollen type-IV: Justicia adhatoda-type, Pollen type-V:Lepidagathis incurva-type, Pollen type- VI: Peristrophe paniculata-type, Pollen type-VII: Ruellia patula-type and Pollen ...

2010-12-01

427

Association tests in nuclear families.

We construct two families of refinements of the (projectivized) support variety of a finite dimensional module $M$ for a finite group scheme $G$. For an arbitrary finite group scheme, we associate a family of {\\it non maximal rank varieties} $\\Gamma^j(G)_M$, $1\\leq j \\leq p-1$, to a $kG$-module $M$. For $G$ infinitesimal, we construct a finer family of locally closed subvarieties $V^{\\ul a}(G)_M$ of the variety of one parameter subgroups of $G$ for any partition $\\ul a$ of $\\dim M$. For an arbitrary finite group scheme $G$, a $kG$-module $M$ of constant rank, and a cohomology class $\\zeta$ in $\\HHH^1(G,M)$ we introduce the {\\it zero locus} $Z(\\zeta) \\subset \\Pi(G)$. We show that $Z(\\zeta)$ is a closed subvariety, and relate it to the non-maximal rank varieties. We also extend the construction of $Z(\\zeta)$ to an arbitrary extension class $\\zeta \\in \\Ext^n_G(M,N)$ whenever $M$ and $N$ are $kG$-modules of ...

2011-01-01

428

Association study of SNAP25 and schizophrenia in Irish family and case-control samples.

We present a conditional likelihood approach for testing linkage disequilibrium in nuclear families having multiple affected offspring. The likelihood, conditioned on the identity-by-descent (IBD) structure of the sibling genotypes, is unaffected by familial correlation in disease status that arises from linkage between a marker locus and the unobserved trait locus. Two such conditional likelihoods are compared: one that conditions on IBD and phase of the transmitted alleles and a second which conditions only on IBD of the transmitted alleles. Under the log-additive model, the first likelihood is equivalent to the allele-counting methods proposed in the literature. The second likelihood is valid under the added assumption of equal male and female recombination fractions. In a simulation study, we demonstrated that in sibships having two or three affected siblings the score test from each likelihood had the correct test size for testing ...

2001-01-01

429

SNAP25 occurs on chromosome 20p12.2, which has been linked to schizophrenia in some samples, and recently linked to latent classes of psychotic illness in our sample. SNAP25 is crucial to synaptic functioning, may be involved in axonal growth and dendritic sprouting, and its expression may be decreased in schizophrenia. We genotyped 18 haplotype-tagging SNPs in SNAP25 in a sample of 270 Irish high-density families. Single marker and haplotype analyses were performed in FBAT and PDT. We adjusted for multiple testing by computing q values. Association was followed up in an independent sample of 657 cases and 411 controls. We tested for allelic effects on the clinical phenotype by using the method of sequential addition and 5 factor-derived scores of the OPCRIT. Nine of 18 SNPs had P values Irish family sample. Although we failed to replicate this in an independent sample, this gene should be further tested in other samples. PMID:19806613

2010-03-01

430

Amyloidosis

Reticulate eruptions. Part 1: Vascular networks and physiology

The subjects covered in this Symposium range through almost every clinical medical specialty. From an average of one paper in each of the past three Symposiums, the explosive interest in cerebral amyloidosis has led to the presentation of 12 papers on this subject in the present volume. The genetically predisposed familial amyloidotic processes, such as the polyneuropathies and familial Mediterranean fever have also stimulated extensive and intriguing investigations which have revealed the striking effect of a single amino acid substitution in transforming a normal protein into a lethal ''amyloidogenic'' one. This Symposium clearly depicts the advances since the first amyloid fibril protein was definitively identified and defined 14 years ago. Since all amyloid fibril proteins so far described are variants of normal proteins, attention to gene abnormalities now becomes a significant focus as well as the pathogenic sequences which lead in these ...

1984-11-09

431

British Library Electronic Table of Contents (United Kingdom)

Abstract Reticulate pattern is one of the most important dermatological signs of a pathological process involving the superficial vascular networks. Vascular malformations, such as cutis marmorata congenita telangiectasia and benign forms of livedo reticularis, and sinister conditions, such as meningococcal meningitis or Sneddon's syndrome, can all present with a reticulate pattern. The clinical presentation and morphology is determined by the nature and extent of the underlying pathology and the involvement of a particular vascular network. This review has been divided into four instalments. In the present paper, we discuss the anatomy and physiology of the complex network of vascular structures that support the function of the skin and subcutis.

2011-01-01

432

Radioimmunoassay of serum myoglobin in polymyositis and other conditions

Radioimmunoassay of serum myoglobin was done in 53 patients with polymyositis syndromes and other conditions. Serum myoglobin values in 33 healthy subjects ranged from 4 to 77 [mean 33.3 +/- 19.8 (SD)] ng/ml. Fifty percent of polymyositis patients had elevated serum myoglobin levels (greater than 80 ng/ml). Serum myoglobin values in polymyositis patients fluctuated more sensitively than CPK and GOT. Combined estimation of myoglobin and CPK offers advantages for the detection of muscle injury and the prediction of disease exacerbation.

433

Radiobiology

Improvement of muscle strenght independently of analgesic effect following spinal cord stimulation. A case report.

This text-book (electronic book - multi-media CD-ROM) constitutes a course-book - author's collection of lectures. It consists of 13 lectures in which the reader acquaints with the basis of radiobiology: Introduction to radiobiology; Physical fundamentals of radiobiology; Radiation of cells; Modification of radiation damage of cells; Reparation of radiation damage of cells; Radiation syndromes and their modification; Radiation injury; Radiation damage of tissues; Effect of radiation on embryo and fetus; Biological effects of incorporated radionuclides; Therapy of acute irradiation sickness; Delayed consequences of irradiation; Radiation oncology and radiotherapy. This course-book may be interesting for students, post-graduate students of chemistry, biology, physics, medicine as well as for teachers, scientific workers and physicians. (author)

434

Depression and chronic fatigue in the patient with chronic pain.

Spinal cord stimulation (SCS) is frequently used for relief of chronic benign pain resistant to conservative therapies. Clinical practice suggests, at least in patients with failed back surgery syndrome (FBSS), the possibility that SCS significantly improves motor performances. We present here the case of a 41-years-old female patient with FBSS, who showed a clear improvement in muscle strength after SCS, persisting at 6-months follow-up. We speculate that the electrical stimulation of posterior columns could potentiate the caudal, segmental spinal reflexes resulting in a facilitation of motoneurons activation. PMID:16175150

2004-12-01

435

Computerized tomography of adrenal glands in the investigation of Cushing's syn

Chronic benign pain is commonly associated with chronic fatigue and depression. Depression and chronic fatigue syndrome are also associated with each other and often include pain. Psychologic factors are prominent in these conditions, and they may share neurobiologic factors as well. Management requires separately addressing each component of patients' distress and usually includes physical rehabilitation, education, administration of nonhabituating medications and often counseling. Depression may be a favorable prognostic sign, as it suggests a treatable condition and provides incentive for recovery. PMID:1876618

1991-06-01

436

Azidothymidine: crystal structure and possible functional role of the azido group

Computerized tomography of the adrenal glands was performed in 10 patients with Cushing's syndrome using a G.E. 8800 CT/T Body Scanner. The tomographic findings of unilateral adrenal masses in 4 patients were confirmed by surgery. In the remaining 6 patients, computerized tomography did not identify any masses, and both glands were well visualized and showed normal shape. In these patients, measurement of the adrenal glands revealed both normal (n=1) and enlarged glands (n=5). The findings of adrenalectomy (n=4) or transphenoidal surgery and follow-up (n=2) established the diagnosis of adrenal phyperplasia in all patients. (Author).

437

Radiation therapy for Kasabach-Merritt syndrome. Analysis of unfavorable factors in 5 children

The crystal and molecular structures of the anti-acquired immunodeficiency syndrome agent 3'-azido-3'-deoxythymidine (AZT) have been determined by x-ray diffraction. There are two crystallographically independent AZT molecules in the crystal asymmetric unit; they have similar conformation and differ primarily in the glycosyl torsion angle. Comparisons with a hydrated thymidylate structure indicate that the azido group does not significantly affect the gross conformational preference of the molecule. The comparisons also suggest possible functional roles for the azido group in enzyme binding.

1987-12-01

438

Computer vision syndrome: a review of ocular causes and potential treatments.

During the past 10 years, five infants with Kasabach-Merritt syndrome (K-M) receiving radiation therapy were reported. We investigated whether radiation therapy for K-M was useful and what the unfavorable factors of K-M were. During the past 10 years, we have treated five infants with K-M. The syndrome occurred at ages ranging from birth to 4 months. The incidence of female to male ratio was 3:2. Among 5 cases, the site of hemangioma was as follows; shoulder, anterior chest wall, lower abdominal wall, face and neck and inguinal site. All 5 cases received medication to control the coagulopathy including prednisone and blood transfusion at first. Because the platelet count and the bleeding tendency did not improve in any case, these cases received radiation therapy. Total dose ranged from 5 to 10 Gy and fraction-size ranged from 0.5 to 1.75 Gy. Irradiation session was 2 or 3 times per week. In 5 cases, 4 cases showed cure of bleeding tendency and ...

1996-03-01

439

Tight contact structures and genus one fibered knots

Citation information: Rosenfield M. Computer vision syndrome: a review of ocular causes and potential treatments. Ophthalmic Physiol Opt 2011, 31, 502-515. doi: 10.1111/j.1475-1313.2011.00834.x ABSTRACT: Computer vision syndrome (CVS) is the combination of eye and vision problems associated with the use of computers. In modern western society the use of computers for both vocational and avocational activities is almost universal. However, CVS may have a significant impact not only on visual comfort but also occupational productivity since between 64% and 90% of computer users experience visual symptoms which may include eyestrain, headaches, ocular discomfort, dry eye, diplopia and blurred vision either at near or when looking into the distance after prolonged computer use. This paper reviews the principal ocular causes for this condition, namely oculomotor anomalies and dry eye. Accommodation and vergence responses to electronic screens appear ...

2011-04-12

440

The Allocation of Treatment Responsibility scale: A novel tool for assessing patient and caregiver management of pediatric medical treatment regimens

We study contact structures compatible with genus one open book decompositions with one boundary component. Any monodromy for such an open book can be written as a product of Dehn twists around dual non-separating curves in the once-punctured torus. Given such a product, we supply an algorithm to determine whether the corresponding contact structure is tight or overtwisted when the monodromy is pseudo-Anosov. We rely on Ozsv{\\'a}th-Szab{\\'o} Heegaard Floer homology in our construction and, in particular, we completely identify the $L$-spaces with genus one, one boundary component, pseudo-Anosov open book decompositions. Lastly, we reveal a new infinite family of hyperbolic three-manifolds with no co-orientable taut foliations, extending the family discovered in \\cite{RSS}.

2006-01-01

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441

British Library Electronic Table of Contents (United Kingdom)

Pai ALH, Gray E, Kurivial K, Ross J, Schoborg D, Goebel J. The Allocation of Treatment Responsibility scale: A novel tool for assessing patient and caregiver management of pediatric medical treatment regimens. Pediatr Transplantation 2010: 14:993 999. 2010 John Wiley & Sons A/S. Abstract: The purpose of the current study is to report preliminary psychometric properties of the ATR scale, a brief measure of the distribution of treatment tasks across the family members of children with a kidney transplant. Pediatric patients with renal transplants (ages 7 18 yr) and their caregivers completed the ATR and measures of adherence and family functioning. Internal consistency for the ATR (total score and subscales) was strong (range = 0.75 0.93). Validity for the ATR was supported by significant co...

2010-01-01

442

Local Perception of Environmental Change in a Semi-Arid Area of Northeast Brazil: A New Approach for the Use of Participatory Methods at the Level of Family Units

British Library Electronic Table of Contents (United Kingdom)

The diversity of plant resources in the Brazilian semi-arid region is being compromised by practices related to agriculture, pastures, and forest harvesting, especially in areas containing Caatinga vegetation (xeric shrublands and thorn forests). The impact of these practices constitutes a series of complex factors involving local issues, creating a need for further scientific studies on the social-environmental dynamics of natural resource use. Through participatory methods, the present study analyzed people?s representations about local environmental change processes in the Brazilian semi-arid region, taking into consideration local production systems, natural resources, and their importance. Environmental historical graphs were developed with nine local families to analyze landscape cha...

2011-01-01

443

Linear family of Lie brackets on the space of matrices $Mat(n\\times m,\\K)$ and Ado's Theorem

Help-Seeking for Children with Mental Health Problems: Parents? Efforts and Experiences

In this paper we classify a linear family of Lie brackets on the space of rectangular matrices $Mat(n\\times m,\\K)$ and we give an analogue of the Ado's Theorem. We give also a similar classification on the algebra of the square matrices $Mat(n, \\K)$ and as a consequence, we prove that we can't built a faithful representation of the $(2n+1)$-dimensional Heisenberg Lie algebra $\\mathfrak{H}_n$ in a vector space $V$ with $\\dim V\\leq n+1$. Finally, we prove that in the case of the algebra of square matrices $Mat(n,\\K)$, the corresponding Lie algebras structures are a contraction of the canonical Lie algebra $\\mathfrak{gl}(n,\\K)$.

2008-01-01

444

British Library Electronic Table of Contents (United Kingdom)

Parents who contacted 1 of 15 children?s mental health agencies in Ontario, Canada reported on where and why they were seeking mental health services for their 4- to 17-year-old children. Parents contacted?an average of four agencies (?1.7; range?=?1?14) in the previous year. Approximately one-half of parents were looking for either multiple types of treatment, or help for different problems, across agencies. The complex pattern of help-seeking evidenced in our study likely increases the burden on the mental health care system and on families, and may reduce the likelihood that families will connect with the most appropriate treatment.

2011-01-01

445

Hardware standardization for embedded systems

Customized airfoils and their impact on VAWT (Vertical-Axis Wind Turbine) cost of energy

Reactor Control Division (RCnD) has been one of the main designers of safety and safety related systems for power reactors. These systems have been built using in-house developed hardware. Since the present set of hardware was designed long ago, a need was felt to design a new family of hardware boards. A Working Group on Electronics Hardware Standardization (WG-EHS) was formed with an objective to develop a family of boards, which is general purpose enough to meet the requirements of the system designers/end users. RCnD undertook the responsibility of design, fabrication and testing of boards for embedded systems. VME and a proprietary I/O bus were selected as the two system buses. The boards have been designed based on present day technology and components. The intelligence of these boards has been implemented on FPGA/CPLD using VHDL. This paper outlines the various boards that have been developed with a brief description. (author)

2010-02-01

446

Associations between a highly invasive species and native macrophytes differ across spatial scales

Sandia National Laboratories has developed a family of airfoils specifically designed for use in the equatorial portion of a Vertical-Axis Wind Turbine (VAWT) blade. An airfoil of that family has been incorporated into the rotor blades of the DOE/Sandia 34-m diameter VAWT Test Bed. The airfoil and rotor design process is reviewed. Comparisons with data recently acquired from flow visualization tests and from the DOE/Sandia 34-m diameter VAWT Test Bed illustrate the success that was achieved in the design. The economic optimization model used in the design is described and used to evaluate the effect of modifications to the current Test Bed blade. 1 tab., 11 figs., 13 refs.

1990-01-01

447

British Library Electronic Table of Contents (United Kingdom)

The association between invasive and native species varies across spatial scales and is affected by phylogenetic relatedness, but these issues have rarely been addressed in aquatic ecosystems. In this study, we used a non-native, highly invasive species of Poaceae (tropical signalgrass) to test the hypotheses that (i) tropical signalgrass success correlates negatively with success of most native species of macrophytes at fine spatial scales, but its success correlates positively or at random with natives at coarse spatial scales, and that (ii) tropical signalgrass is less associated with native species belonging to the family Poaceae than with species belonging to other families (Darwin?s naturalization hypothesis). We used a dataset obtained at fine (0.25?m2) and coarse (ca. 1,000?m2) sca...

2011-01-01

448

Association study of SNAP25 and schizophrenia in Irish family and case-control samples

British Library Electronic Table of Contents (United Kingdom)

SNAP25 occurs on chromosome 20p12.2, which has been linked to schizophrenia in some samples, and recently linked to latent classes of psychotic illness in our sample. SNAP25 is crucial to synaptic functioning, may be involved in axonal growth and dendritic sprouting, and its expression may be decreased in schizophrenia. We genotyped 18 haplotype-tagging SNPs in SNAP25 in a sample of 270 Irish high-density families. Single marker and haplotype analyses were performed in FBAT and PDT. We adjusted for multiple testing by computing q values. Association was followed up in an independent sample of 657 cases and 411 controls. We tested for allelic effects on the clinical phenotype by using the method of sequential addition and 5 factor-derived scores of the OPCRIT. Nine of 18 SNPs had P values <...

2010-01-01

449

Approaching the ?Resistant:? Exploring East Asian International Students? Perceptions of Therapy and Help-Seeking Behavior Before and After They Arrived in the United States

British Library Electronic Table of Contents (United Kingdom)

In this study we investigated cultural, familial, and individual beliefs that influenced international students? perceptions of therapy and help-seeking behaviors. Included were changes in perception or behavior before and after the students came to the US, and factors that influenced help-seeking behaviors. Six international students from East Asian countries where English is a foreign language, including Taiwan, Mainland China, Japan, and South Korea, were interviewed. We used semi-structured interviews and participant observations for collecting data. The findings indicated changes after students came to the US. Further discussions focus on encouraging and discouraging factors relative to seeing therapists, and culturally sensitive interventions for family therapy clinicians.

2011-01-01

450

An empirical analysis of factors affecting adolescent attachment in adoptive families with homosexual and straight parents

British Library Electronic Table of Contents (United Kingdom)

Data were collected on 154 adoptive families with gay/lesbian and straight adoptive parents (154 parent respondents and 210 adolescent respondents). This study was principally interested in factors affecting adolescent attachment including parent sexual orientation, adolescent and parent life satisfaction, and parent level of relationship satisfaction with their adopted child as well as other key parent, child and adoption characteristics. The results suggest that higher level of adopted adolescent attachment to parents is not related to adoptive parent sexual orientation. Adolescent attachment to parents is related to adolescent life satisfaction; parent level of relationship satisfaction with their adopted child, number of placements prior to adoption, and adolescent's current age. Adole...

2009-01-01

451

A multifactorial strategy of pain management is associated with less pain in scheduled vaccination of children. A study realized by family practitioners in 239 children aged 4-12 years old

British Library Electronic Table of Contents (United Kingdom)

Background and aims. The multiplicity of vaccine injections during childhood leads to iterative painful and stressful experiences which may lead in turn to anticipated pain and then possibly to a true needle phobia. We aimed at evaluating a multifactorial strategy of pain management combining pharmacological and non-pharmacological approaches during vaccination, as compared to usual care, in 4- to 12-year-old children. Methods. In all, 239 children were enroled by 25 family practitioners in an open-label study. After a pseudo-randomization, usual pain management (n = 132) was compared to a multifactorial strategy (n = 107) associating preliminary application of an anesthesic patch, preferential use of specified vaccines, child education by the parents and the doctor, parental accompaniment...

2008-01-01

452

bHLH-PAS family transcription factor methoprene-tolerant plays a key role in JH action in preventing the premature development of adult structures during larval-pupal metamorphosis

Visualization of inositol 1,4,5-trisphosphate receptors on the nuclear envelope outer membrane by deep etching electron microscopy

The biological actions of juvenile hormones are well studied; they regulate almost all aspects of an insect’s life. However, the molecular actions of these hormones are not well understood....Full Text Available

2008-07-01

453

Transitional nuclei and triaxial shapes

SummaryThe receptors for the second messenger InsP₃ comprise a family of closely related ion channels that release Ca²⁺ from intracellular stores, most prominently...Full Text Available

2010-09-01

454

The rare earth antimonates: spectroscopic properties, crystal field and paramagnetic susceptibility simulations

Evidence for triaxial nuclear shapes from families of unique-parity states in transitional odd-A nuclei around mass A=190 and A=130 is reviewed. The experimental data are analysed within the odd-A triaxial core model. Regular two-dimensional band patterns are found in experiment and are shown to be a consequence of broken axial symmetry. Recent theoretical developments are discussed including the question of how stable the triaxial shapes are.

455

The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia?coli

The rare earth antimonates RE_3Sb_5O_1_2 constitute an isostructural series, where the rare earth site symmetry is S_4. The spectroscopic properties of pure or doped compounds of this family are studied in order to derive their energy level schemes and to simulate them through the crystal field theory, by using the approximated D_2_d potential. The paramagnetic susceptibilities are calculated with the derived wavefunctions and compared to experiment.

1990-09-01

456

The Phenomics and Expression Quantitative Trait Locus Mapping of Brain Transcriptomes Regulating Adaptive Divergence in Lake Whitefish Species Pairs (Coregonus sp.)

Thioredoxin reductase, lipoamide dehydrogenase, and glutathione reductase are members of the pyridine nucleotide–disulfide oxidoreductase family of dimeric flavoenzymes. The mechanisms and structures...Full Text Available

1997-04-15

457

The Limits and Possibilities of Tracking: Some Evidence from Taiwan.

We used microarrays and a previously established linkage map to localize the genetic determinants of brain gene expression for a backcross family of lake whitefish species pairs (Coregonus sp.). Our...Full Text Available

2008-09-01

458

Tailored airfoils for vertical axis wind turbines

Uses a survey of educational attainment in urban Taiwan to explore the effects of ability grouping. Argues that because of the nature of educational institutionalization in Taiwan (universal basic education, a national curriculum, entrance examinations governing access to postcompulsory schooling) tracking reduces rather than accentuates the influence of family background. (MJP)

1996-12-01

459

Shear-free rotating inflation

The evolution of a family of airfoil sections designed to be used as blade elements of a vertical axis wind turbine (VAWT) is described. This evolution consists of extensive computer simulation, wind tunnel testing and field testing. The process reveals that significant reductions in system costs-of-energy and increases in fatigue lifetime may be expected for VAWT systems using these blade elements.

1984-11-01

460

Sequence analysis of two alleles reveals that intra-and intergenic recombination played a role in the evolution of the radish fertility restorer (Rfo)

We demonstrate the existence of shear-free cosmological models with rotation and expansion which support inflationary scenarios. The corresponding metrics belong to the family of spatially homogeneous models with the geometry of the closed universe (Bianchi type IX). We show that the global vorticity does not prevent inflation and can even accelerate it.

2002-08-15

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461

Rotation in string cosmology

BackgroundLand plant genomes contain multiple members of a eukaryote-specific gene family encoding proteins with pentatricopeptide repeat (PPR) motifs. Some PPR proteins were shown...Full Text Available

462

Rotation in string cosmology

We describe exact cosmological solutions with rotation and expansion in the low-energy effective string theory. These models are spatially homogeneous (closed Bianchi type IX) and they belong to the family of shear-free metrics which are causal (no closed timelike curves are allowed), admit no parallax effects and do not disturb the isotropy of the background radiation. The dilaton and the axion fields are nontrivial, in general, and we consider both cases with and without the central charge (effective cosmological constant)

2003-03-21

463

Rin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22

We describe exact cosmological solutions with rotation and expansion in the low-energy effective string theory. These models are spatially homogeneous (closed Bianchi type IX) and they belong to the family of shear-free metrics which are causal (no closed timelike curves are allowed), admit no parallax effects and do not disturb the isotropy of the background radiation. The dilaton and the axion fields are nontrivial, in general, and we consider both cases with and without the central charge (effective cosmological constant).

2003-03-21

464

Recovering quantum graphs from their Bloch spectrum

RIN proteins serve as guanine nucleotide exchange factors for Rab5a. They are characterized by the presence of a RIN homology domain and a C-terminal Vps9 domain. Currently three family members have...Full Text Available

2011-06-01

465

Practical approach to the loss of smell

We define the Bloch spectrum of a quantum graph to be the collection of the spectra of a family of Schr\\"odinger operators parametrized by the cohomology of the quantum graph. We show that the Bloch spectrum determines the Albanese torus, the block structure and the planarity of the graph. It determines a geometric dual of a planar graph. This enables us to show that the Bloch spectrum completely determines planar 3-connected quantum graphs.

2011-01-01

466

On the triaxial deformation in transitional odd-A nuclei

Loss of the sense of smell can be easily confirmed in any physician's office by having the patient try to identify various odors. The etiology of anosmia can be extremely varied, including nasopharyngeal disorders such as rhinitis and tumors; neurologic conditions such as head trauma, neoplasms, vascular lesions and infections of the central nervous system; viral infections; familial and congenital disorders; drugs; industrial exposure; endocrine diseases, and several other disorders. The prognosis of anosmia is guarded, and its treatment depends on the etiology.

1982-09-01

467

Nonsyndromic bilateral and unilateral optic nerve aplasia: first familial occurrence and potential implication of CYP26A1 and CYP26C1 genes

The essential difference as well as the apparent identity between the triaxial-rotor model and the gamma-vibrational model have been discussed. From the gamma decay mode, the [19/2"-]_1 states of the j = 11/2"- family in "1"8"7Ir and "1"8"9Ir have been identified as the K = j + 4 states, the presence of which contradicts the particle plus triaxial-rotor model. (author).

468

Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C

PurposeOptic nerve aplasia (ONA, OMIM 165550) is a very rare unilateral or bilateral condition that leads to blindness in the affected eye, and is usually associated with other ocular...Full Text Available

469

Molecular cloning of the N-terminus of GTBP

Charcot-Marie-Tooth disease type 2C (CMT2C) is an autosomal dominant neuropathy characterized by limb, diaphragm, and laryngeal muscle weakness. Two unrelated families with CMT2C showed significant...Full Text Available

2010-02-01

470

Modularity for bio business growth

Defects in mismatch repair genes cause the genetic instability characteristic of hereditary nonpolyposis colorectal cancer and a subset of sporadic colon tumors. The newest member of the mismatch repair gene family, GTBP, has recently been identified as a partial cDNA. Here, we describe the isolation of its 5{prime} terminus, allowing definition of the entire coding region. Several polymorphisms within the 5{prime} end were identified and are presented. 13 refs., 1 fig.

1996-02-01

471

British Library Electronic Table of Contents (United Kingdom)

Interchangeable technology from Flexicon Liquid Filling, a business division of Watson-Marlow Pumps Group, has helped family-run diagnostic reagent manufacturer, Hart Biologicals Ltd, to accommodate business growth with the recent upgrade to a tabletop bottle filling and capping machine. A peristaltic dispensing pump is crucial for succes

2011-01-01

472

MicroRNA Let-7f Inhibits Tumor Invasion and Metastasis by Targeting MYH9 in Human Gastric Cancer

British Library Electronic Table of Contents (United Kingdom)

BackgroundMicroRNAs (miRNAs) are important regulators that play key roles in tumorigenesis and tumor progression. A previous report has shown that let-7 family members can act as...Full Text Available

473

Messbare IT-Sicherheit

Zusammenfassung Der vom Bundesamt f?r Sicherheit in der Informationstechnik (BSI) entwickelte Ansatz des IT-Grundschutzes war bereits Gegenstand von Beitr?gen in der DuD. Inzwischen hat das ?Grundschutzhandbuch? Eingang in die internationale Standard-Familie ISO 2700x gefunden. Der Autor berichtet ?ber die Erfahrungen mit den ersten durchgef?hrten Zertifizierungen nach dem neuen ISO-Standard auf der Basis von IT-Grundschutz.

2007-01-01

474

Mapping quantitative trait loci (QTL) in sheep. II. Meta-assembly and identification of novel QTL for milk production traits in sheep

Lagrange-Function Approach to Real-Space Order-N Electronic-Structure Calculations

An (Awassi × Merino) × Merino backcross family of 172 ewes was used to map quantitative trait loci (QTL) for different milk production traits on a framework map of 200 loci across all...Full Text Available

475

Klebsiella pneumoniae Strains Producing Extended-Spectrum ?-Lactamases in Spain: Microbiological and Clinical Features^?

The Lagrange functions are a family of analytical, complete, and orthonormal basis sets that are suitable for efficient, accurate, real-space, order-N electronic-structure calculations. Convergence is controlled by a single monotonic parameter, the dimension of the basis set, and computational complexity is lower than that of conventional approaches. In this paper we review their construction and applications in linearscaling electronic-structure calculations.

2006-04-01

476

Japan Groundwork Association to aid disaster support effort

Extended-spectrum β-lactamases (ESBL) of the CTX-M, SHV, and TEM families were recognized in 76 (67%), 31 (27%), and 6 (5%) isolates, respectively, among 162 ESBL-producing Klebsiella...Full Text Available

2011-03-01

477

Isomeric prostaglandin F2 compounds arising from prostaglandin D2: a family of icosanoids produced in vivo in humans.

...six months Organising local tours of the area for up to 1000 affected families in the Izu Penninsula area around Mount Fuji Mobile food stalls that wlll serve up to 10,000 bottles of water and 10,000 servings of food Mobile human waste disposal units Building northern Japan support committees Browser does not support script. Browser does not support script. For further information, please contact: Garry Campbell, PR & ...

478

Intragenic rearrangements of a mycoreovirus induced by the multifunctional protein p29 encoded by the prototypic hypovirus CHV1-EP713

Prostaglandin (PG) D2 has been shown to be transformed by human 11-ketoreductase to 9 alpha,11 beta-PGF2, a biologically active metabolite that is produced in vivo. During the course of developing a...Full Text Available

1988-01-01

479

Installation of heat pumps

Mycoreovirus 1 (MyRV1), a member of the Reoviridae family possessing a genome consisting of 11 dsRNA segments (S1–S11), and the prototype hypovirus (CHV1-EP713)...Full Text Available

2008-12-01

480

Human endogenous retrovirus HERV-K(HML-2) encodes a stable signal peptide with biological properties distinct from Rec

Heat pumps can be installed indoors or outdoors. H. Klein investigates which site would be preferable for a one-family house. Advantages and disadvantages with regard to necessary space, noise, maintenance and repair are discussed; heat losses in both cases of installations are dealt with. Mathematic calculation shows that indoor installation is safer and more adequate in terms of energy savings.

1982-06-01

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481

Homotopy type and A?-group structure

BackgroundThe human endogenous retrovirus HERV-K(HML-2) family is associated with testicular germ cell tumors (GCT). Various HML-2 proviruses encode viral proteins such as Env and...Full Text Available

482

Helper T-Cell Epitopes Encoded by the Babesia bigemina rap-1 Gene Family in the Constant and Variant Domains Are Conserved among Parasite Strains

The aim of the paper is to define and study algebraic operations closely related to the group structure on the homotopy groups of topological spaces. These are certain many-place operations on the homotopy groups. The family of these operations induces an algebraic structure on the homotopy groups, which is called an A?-group structure by analogy with the A?-structures introduced by Stasheff.

1998-10-31

483

Green tea increases anti-inflammatory tristetraprolin and decreases pro-inflammatory tumor necrosis factor mRNA levels in rats

Among important candidates for babesial vaccines are apical complex proteins, including rhoptry-associated protein 1 (RAP-1) from Babesia bovis and B. bigemina, which...Full Text Available

1998-04-01

484

Expression of V642 APP mutant causes cellular apoptosis as Alzheimer trait-linked phenotype.

BackgroundTristetraprolin (TTP/ZFP36) family proteins have anti-inflammatory activity by binding to and destabilizing pro-inflammatory mRNAs such as Tnf mRNA, and represent a potential...Full Text Available

485

Estimates of Amplitudes of Transient Regimes in Quasi-Controllable Discrete Systems

APP is a transmembrane precursor of beta-amyloid. In dominantly inherited familial Alzheimer's disease (FAD), point mutations V6421, V642F and V642G have been discovered in APP695. Here we show that...Full Text Available

1996-02-01

486

Deep-sea mystery solved: astonishing larval transformations and extreme sexual dimorphism unite three fish families

Families of regimes for discrete control systems are studied possessing a special quasi-controllability property that is similar to the Kalman controllability property. A new approach is proposed to estimate the amplitudes of transient regimes in quasi-controllable systems. Its essence is in obtaining of constructive a priori bounds for degree of overshooting in terms of the quasi-controllability measure. The results are applicable for analysis of transients, classical absolute stability problem and, especially, for stability problem for desynchronized (asynchronous, switching) systems.

2009-01-01

487

Crystallization and preliminary X-ray diffraction studies of two thermostable ?-galactosidases from glycoside hydrolase family 36

The oceanic bathypelagic realm (1000–4000 m) is a nutrient-poor habitat. Most fishes living there have pelagic larvae using the rich waters of the upper 200 m. Morphological...Full Text Available

2009-04-23

488

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

α-Galactosidases from thermophilic organisms have gained interest owing to their applications in the sugar industry. The α-galactosidases AgaA, AgaB and AgaA A355E mutant from Geobacillus...Full Text Available

489

Australia 2020 Summit - Government Response - Strengthening communities, supporting families and social inclusion

Metastatic disease is a primary cause of cancer-related death, and factors governing tumor cell metastasis have not been fully elucidated. Here, we address this question by using tumor cell lines derived...Full Text Available

2009-09-15

490

Apoptotic pathways as regulators of recombination

Government should model good practice in social inclusion and diversity.Apply a social inclusion test ...Government should model good practice in social inclusion and diversity.Apply a social inclusion test ...Government should model good practice in social inclusion and diversity.Apply a social inclusion test

491

An online monitoring system for nuclear waste storage

Apoptosis, or programmed cell death (PCD), is a fundamental process that protects organismal integrity. In earlier work, we demonstrated that over-expression of either of two anti-apoptotic members of the BCL-2 family (BCL-2 or BCL-X L could elevate the frequency of radiation-induced mutations at the autosomal TK1 locus in human TK6 lymphoblasts that express wild-type TP53. Ectopic expression of BCL-X L also elevated the frequencies of double-strand break-induced gene conversion. The purpose of this study is to determine if BCL-2 family proteins promote radiation mutagenesis indirectly through their suppression of PCD, or whether the 'pro-mutagenic' function of these proteins can be separated from their anti-apoptotic function. We developed stable transfectants of TK6 cells that express a mutated form of BCL-X L with a single amino acid substitution in the BH1 domain that is known to interfere with the ability to suppress PCD (BCL-X L ...

2003-08-17

492

Adiabatic flame temperature estimates of lean fuel/air mixtures

We propose a system for the on-line monitoring of short and medium term radioactive waste repositories. Such a system is distributed, fine-grained, robust, reliable, and must be based on low-cost components. It could, in principle, open new perspectives on the modality of waste packaging and storage. In particular we propose to employ a new family of cheap and powerful micro sensors to be placed in shape of a fine grid around each single drum. (authors)

2009-06-07

493

AECL IMPELA electron beam industrial irradiators

This paper reports new formulas of adiabatic flame temperature. They are functionally expressed in terms of fuel/air ratio, reaction pressure, and the number of carbon atoms in the individual fuel. Among the fuels presently considered for the formulas are members of paraffin, aromatic and olefin families, acetylene, alcohols, and hydrogen.

1983-01-01

494

A simple model of dimensional collapse

A family of industrial irradiators is being developed by AECL to cover an electron-beam energy range from 5 to 18 MeV at beam powers between 20 and 250 kW. The IMPELA family of irradiators is designed for push button, reliable operation. The major irradiator components are modular, allowing for later upgrades to meet increased demands in either electron or X-ray mode. Interface between the control system, irradiator availability and dose quality assurance is in conformance with the most demanding specifications. The IMPELA irradiators use a klystron-driven, standing-wave, L-band accelerator structure with direct injection from a rugged, triode electron gun. Direct control of the accelerating field during the beam pulse ensures constant output beam energy, independent of beam power. The first member of the family, the IMPELA 10/50 (10 MeV, 50 kW), is in the final stages of assembly at Chalk River Nuclear Laboratories. The ...

495

A divergent Tbx6-related gene and Tbx6 are both required for neural crest and intermediate mesoderm development in Xenopus

We consider a simple model of d families of scalar field interacting with geometry in two dimensions. The geometry is locally flat and has only global degrees of freedom. When d0 it collapses to a one dimensional manifold. The model has some, but not all, of the characteristics believed to be features of the full theory of conformal matter interacting with quantum gravity which has local geometric degrees of freedom.

1996-01-01

496

"9"9"mTc-tetrofosmin uptake by peripheral neuroectodermal tumor (PNET) and Ewing's sarcoma: a possible technique to differentiate one from other

AbstractT-box family transcription factors play many roles in Metazoan development. Here we characterise Tbx6r, a unique Tbx6 paralogue isolated from the amphibian Xenopus....Full Text Available

2010-04-01

497

Quantitative 1-123 IMP SPECT, MR imaging, and neuropsychologic testing in AIDS dementia

"9"9"mTc-tetrofosmin has been used in the imaging of cancers of diverse origin. In this report the use of it in the family of round cell tumors, mainly Ewing's sarcoma and peripheral neuroectodermal tumor (PNET), where differentiation between the two is not always simple on the basis of histopathological features alone is discussed

1998-09-01

498

Opportunistic esophagitis in AIDS: Radiographic diagnosis

The authors have performed I-123 IMP single- photon emission CT (SPECT) brain imaging on seven mildly demented patients with acquired immunodeficiency syndrome (AIDS) and on seven normal subjects. Pixel-intensity histograms have been analyzed for the fraction of pixels in the lowest quartile of the intensity range. This fraction (F) averaged 17.7% (standard deviation [SD] = 4.3) in the AIDS group and 12.6 (SD = 4.7) in the normal group (P <.05). Regression analysis of neuropsychological testing (NPT) scores vs F yielded a correlation coefficient of.71. The presence or degree of atrophy did not correlate with F or NPT scores.

499

Correlation of MRI and histomorphological findings in bone marrow oedema syndrome of the hip

Between 1983 and 1986, 35 of 90 patients with acquired immunodeficiency syndrome (AIDS) had double-contrast esophagograms to rule out opportunistic esophagitis. The radiographs were reviewed without knowledge of the clinical or endoscopic findings. Candida esophagitis was diagnosed radiographically in 17 patients who had varying degrees of plaque formation and viral esophagitis in three who had discrete ulcers without plaques. All three patients with viral esophagitis (herpes in 2 and cytomegalo virus in one) and 15 of 17 with Candida esophagitis had endoscopic and/or clinical corroboration of the radiographic diagnosis. Thus, the authors' experience suggests that fungal and viral esophagitis can often be differentiated on double-contrast esophagography, so that appropriate antifungal or antiviral therapy can be instituted without need for endoscopic intervention.

500