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Russian (1972). USSR Bagaev, VB Abueva, AA (no.188) p. 137-143.

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PMID:10585377

CERN Document Server

When testing multiple hypothesis in a survey --e.g. many different source locations, template waveforms, and so on-- the final result consists in a set of confidence intervals, each one at a desired confidence level. But the probability that at least one of these intervals does not cover the true value increases with the number of trials. With a sufficiently large array of confidence intervals, one can be sure that at least one is missing the true value. In particular, the probability of false claim of detection becomes not negligible. In order to compensate for this, one should increase the confidence level, at the price of a reduced detection power. False discovery rate control is a relatively new statistical procedure that bounds the number of mistakes made when performing multiple hypothesis tests. We shall review this method, discussing exercise applications to the field of gravitational wave surveys.

International Nuclear Information System (INIS)

For many centuries paper was the main material for recording cultural achievements all over the world. Paper is mostly made from cellulose with small amounts of organic and inorganic additives, which allow its identification and characterization and may also contribute to its degradation. Prior to 1850, paper was made entirely from rags, using hemp, flax and cotton fibres. After this period, due to the enormous increase in demand, wood pulp began to be commonly used as raw material, resulting in rapid degradation of paper. Spectroscopic techniques represent one of the most powerful tools to investigate the constituents of paper documents in order to establish its identification and its state of degradation. This review describes the application of selected spectroscopic techniques used for paper characterization and conservation. The spectroscopic techniques that have been used and will be reviewed include: Fourier-Transform Infrared spectroscopy, Raman ...

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This paper examines the utility of restriction fragment length polymorphisms (RFLPs) for paternity analysis. While, on the average, 99% of falsely accused males can be excluded with the standard battery...Full Text Available

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Genome-wide association studies are designed to discover SNPs that are associated with a complex trait. Employing strict significance thresholds when testing individual SNPs avoids false positives at...Full Text Available

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...2010-10-01 2010-10-01 false Battery or power supply with respect to relay...Signal Systems Standards § 236.206 Battery or power supply with respect to relay; location. The battery or power supply for each signal...

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... 2010-10-01 false Exhaust and battery gases. 229.43 Section 229.43...Requirements § 229.43 Exhaust and battery gases. (a) Products of combustion...under usual operating conditions. (b) Battery containers shall be vented and...

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...2010-10-01 false Department of Energy Directives. 970.0470 Section...Acquisition Regulations System DEPARTMENT OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS ...Matters 970.0470 Department of Energy...

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...2010-10-01 2010-10-01 false Use of Federal Supply Schedules. 8.404 Section 8.404 Federal...REGULATION ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Federal Supply Schedules 8.404 Use of Federal Supply...

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...false Manufacturing and production engineering costs. 31.205-25 Section...205-25 Manufacturing and production engineering costs. (a) The costs of manufacturing and production engineering effort as described in (1)...

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...false Priorities for use of Government supply sources. 208.002 Section 208...ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES 208.002 Priorities for use of Government supply sources. (a)(1)(v)...

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...2010-10-01 2010-10-01 false Battery categories. 183.352 Section 183...and Distribution Systems § 183.352 Battery categories. This section applies to batteries installed to meet the requirements...

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...Shipping 4 2010-10-01 2010-10-01 false Battery installation. 111.15-5 Section 111.15-5... ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Storage Batteries and Battery Chargers: Construction and Installation §...

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...Shipping 4 2010-10-01 2010-10-01 false Battery construction. 111.15-2 Section 111.15-2... ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Storage Batteries and Battery Chargers: Construction and Installation §...

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...2010-10-01 false Standards for health information technology to protect electronic health information...DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION...

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...2010-10-01 false Special rules relating to group health plans. 146.145 Section 146.145 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS FOR THE GROUP HEALTH...

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...2010-10-01 false Who must post a geothermal bond? 3214.10 Section 3214...MINERALS MANAGEMENT (3000) GEOTHERMAL RESOURCE LEASING Personal and... § 3214.10 Who must post a geothermal bond? (a) The lessee...

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...false Payment required for O. and C. timber. 2812.5-1 Section 2812.5-1...5-1 Payment required for O. and C. timber. An applicant will be required...officer of the estimated volume of all timber to be cut, removed, or destroyed,...

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42 Public Health 1 2010-10-01 2010-10-01 false 8-Health Professions Pregraduate Scholarship Program for Indians J Subdivision J Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF...

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42 Public Health 1 2010-10-01 2010-10-01 false 2-Health Professions Recruitment Program for Indians J Subdivision J Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

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...Health 2 2010-10-01 2010-10-01 false Creation of records. 401.120 Section 401.120 Public Health...REQUIREMENTS Confidentiality and Disclosure § 401.120 Creation of records. Records will not be created by compiling...

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...2009-07-01 2009-07-01 false Loading and haulage equipment; operation. 77.1607 Section 77.1607...Loading and Haulage § 77.1607 Loading and haulage equipment; operation. (a) Vehicles shall follow...

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...2010-07-01 2010-07-01 false Loading and haulage equipment; installations. 77.1605 Section 77.1605...Loading and Haulage § 77.1605 Loading and haulage equipment; installations. (a) Cab windows shall...

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...false Guidelines for Human Stem Cell Research Presidential Documents ...2009 Guidelines for Human Stem Cell Research Memorandum for the Heads...scientifically worthy human stem cell research, including human...

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The aim of this study was to evaluate the automated urine test strip analyzer Aution Max AX 4280 which uses strips able to measure 12 urinary parameters. For precision study, we considered glucose, protein, blood, leukocytes, nitrite, and pH and the four first were compared with usual methods: chemical measurement or microscopic examination. Reproducibility of the semi quantitative results was determined as the proportion of results falling into the same concentration range. Within-run reproducibility assessed using urine specimens were between 83% and 96%. Between day on quality controlled materials, it was higher (96%), and leukocytes were shared between two classes 250 and 500 cells/microL. For glucose and proteins, linearity was good and comparison with quantitative methods yielded high correlation. The false negative fraction was low and there was no false positive results. For blood, fraction of false positive was ...

CERN Document Server

We describe a large-scale application of methods for finding plagiarism in research document collections. The methods are applied to a collection of 284,834 documents collected by arXiv.org over a 14 year period, covering a few different research disciplines. The methodology efficiently detects a variety of problematic author behaviors, and heuristics are developed to reduce the number of false positives. The methods are also efficient enough to implement as a real-time submission screen for a collection many times larger.

International Nuclear Information System (INIS)

It was shown that the incorporation of "1"4C-linoleic acid in cerebrosides of normal and psoriatic human skin is different. In psoriatic epidermis and corium the turnover of this fatty acid is significantly elevated. It is suggested that in psoriasis the epidermal cell is not able to build up a regular carbohydrate sequences of lipids because the false carbohydrate chain activates the degradation of glycolipids and in compensating for the increased degradation raises the synthesis rate of glycolipids. (orig./MG).

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In clinical situations where a diagnostic real-time PCR assay is not sensitive enough, leading to low or falsely negative results, or where detection earlier in a disease progression would benefit the...Full Text Available

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...2010-10-01 2010-10-01 false Energy Policy Act target group certification...Acquisition Regulations System DEPARTMENT OF ENERGY CLAUSES AND FORMS SOLICITATION...Provisions and Clauses 952.226-73 Energy Policy Act target group...

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...2010-10-01 false Reserve power supply. 80.917 Section 80.917 Telecommunication...Passenger Boats § 80.917 Reserve power supply. (a) The requirements of this section...March 1, 1957, must have a reserve power supply located on the same deck as the...

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...2010-10-01 false Low-income home energy assistance. 96.48 Section 96...Organizations § 96.48 Low-income home energy assistance. (a) This section applies...Indian tribes under the low-income home energy assistance program. (b) The...

International Nuclear Information System (INIS)

Aim of this study was to evaluate the sensitivity of virtual colonoscopy (CT colonography) in the identification of colorectal cancer and to define the limitations and the advantages of this imaging modality, as well as indications to the examination. It was examined prospectively 62 symptomatic patients aged 36 to 82 years (28 women and 34 men). All patients underwent both conventional and virtual colonoscopy on the same day; the conventional examination allowed exploration of the entire colon. Conventional colonoscopy identified 89 lesions 3-50 mm in diameter, namely 84 benign and 5 malignant lesions. No lesions were identified in 12 patients. CT colonography identified 52 of the 89 lesions, with 57.1% diagnostic accuracy. They were 11 false positives (82.5% positive predictive value and 52.2% specificity) and 37 false negatives (24.5% negative predictive value and 58.4% sensitivity). Sensitivity was significantly higher (85.7%) for polyps ...

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Our purpose was to investigate the usefulness of Lipiodol-CT for detection of residual viable neoplastic tissue in hepatocellular carcinoma (HCC) lesions treated by means of percutaneous ethanol injection (PEI). An emulsion of 5 to 20 ml iodized oil and 50 to 70 mg doxorubicin hydrochloride was intraarterially injected in 18 patients with 25 HCC lesions treated by means of PEI one to 24 months before. At CT performed 3 to 5 weeks after injection, retention of Lipiodol was observed in 9 of 13 tumors that still contained viable neoplastic tissue and in 2 of 12 tumors proven to have undergone complete necrosis after PEI. The sensitivity and specificity of Lipiodol-CT were 69.2% and 83.3%, respectively. Thus, Lipiodol-CT seems to have limited diagnostic value after PEI, probably as a consequence of the alcohol-induced vascular damage, accounting for both false-negative and false-positive results. (orig.).

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Biomonitoring of human populations for exposure to genotoxic/clastogenic agents in the environment or the workplace must depend upon statistical tests for elevations in the frequencies of the biological endpoints being monitored, usually chromosomal aberrations (CA), micronuclei (MN), or sister chromatid exchanges (SCE) in peripheral blood lymphocytes. Statistical tests are based, in turn, upon certain assumptions regarding the distribution of the test statistic. When they are often not recognized as such, tests of significance can be in error, and any conclusion drawn that there is or is not a statistically significant difference between one population sample and another maybe erroneous. In population monitoring this means either false negatives or false positives can result and it is hard to know which is worse. Furthermore, even the intelligent design of studies whose object is to test for an elevated level in an exposed population must ...

CERN Document Server

A method is presented for estimating the background at a given location on a sky map by interpolating the estimated background from a set of concentric annuli which surround this location. If the background is nonuniform but smoothly varying, this method provides a more accurate (though less precise) estimate than can be obtained with a single annulus. Several applications of multi-annulus background estimation are discussed, including direct testing for point sources in the presence of a nonuniform background, the generation of "surrogate maps" for characterizing false alarm rates, and precise testing of the null hypothesis that the background is uniform.

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In this article, self-organizing-map-based video object segmentation is proposed, assuming that either Y-quantification or HSV-quantification can be systematically selected. Given a video sequence, the value of the probability density function for each component value is calculated according to a kernel estimation at the first frame. Some areas randomly chosen from the background are then examined, using each component value, to judge whether or not they include the target object. The quantification is determined so that the frequency of occurrence of false extractions can be reduced. The data presented to the maps are generated based on the selected quantification. Experimental results show that the proposed method recognizes the target object well.

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In 1977 and 1978, Sandia National Laboratories, located in Albuquerque, New Mexico, and operated for the US Department of Energy (DOE), filmed a series of crash and fire tests performed on three casks designed to transport irradiated nuclear fuel assemblies. While the tests were performed to assess the applicability of scale and computer modeling techniques to actual accidents, films of them were quickly pressed into service by the DOE and nuclear utilities as ``proof`` to the public of the safety of the casks. In the public debate over the safety of irradiated nuclear fuel transportation, the films have served as the mainstay for the nuclear industry. Although the scripts of all the films were reviewed by USDOE officials before production, they contain numerous misleading concepts and images, and omit significant facts. The shorter versions eliminated qualifying statements contained in the longer version, and created false impressions. This paper discusses factors ...

British Library Electronic Table of Contents (United Kingdom)

In order to analyze changes in human settlement in Xuzhou city during the past 20 years, changes in land cover and vegetation were investigated based on multi-temporal remote sensing Landsat TM images. We developed a hierarchical classifier system that uses different feature inputs for specific classes and conducted a classification post-processing approach to improve its accuracy. From our statistical analysis of changes in urban land cover from 1987 to 2007, we conclude that built-up land areas have obviously increased, while farmland has seen in a continuous loss due to urban growth and human activities. A NDVI difference approach was used to extract information on changes in vegetation. A false change information elimination approach was developed based on prior knowledge and statistic...

British Library Electronic Table of Contents (United Kingdom)

Abstract Green tea extract showed false-negative results in the determination of glucose via glucose oxidase (GOD) test. This investigation was undertaken to verify and find out the precise mechanism underlying this interference by determining the reaction kinetics of production and reduction of end-point chromophore. The peroxidase step of the GOD test was found to be interfered and phenols of the green tea were the interfering compounds. Green tea interfered and exerted its influence in a dual fashion. A part of the interference was observed as a result of the reduction of the finally formed chromophore, whereas the other form of interference was due to its hydrogen peroxide/free radical-scavenging activity. Reducing potential and the free radical-scavenging activity of the phenols in th...

International Nuclear Information System (INIS)

When energetic bunches of electrons traverse an undulator field, they can spontaneously emit radiation both coherently and incoherently. Although it has generally been assumed that undulator radiation is incoherent at wavelengths short compared to the longitudinal size of the electron bunch, several recent observations have proved this assumption false. Furthermore, the appearance of coherent radiation is often accompanied by a significant increase in radiated power. Here we report observations of strongly enhanced coherent spontaneous radiation together with direct measurements, using transition radiation techniques, of the electron distributions responsible for the coherent emission. We also report demonstrated enhancements in the predicted spontaneous radiated power by as much as 6x10"4 using electron bunch compression. copyright 1996 American Institute of Physics.

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This paper discusses how specialized techniques for machine condition monitoring can help to eliminate false alarms and undetected faults, leading to a truly cost effective predictive maintenance program. It is vital to base the monitoring system on the parameter which will give the most useful information about potential faults and breakdowns. This parameter is generally agreed to be vibration. While oil debris analysis and variations in temperature, geometry and machine speed can all give advance warning of faults, no other parameter can reveal as wide a range of fault types as vibration. The vibration transducers job is to accurately and faithfully convert the vibration into an electric signal for assessment. If this part of the system is weak, reliability will be badly affected. Data integrity is crucial.

CERN Document Server

If two loops are isomorphic, then it is shown that their holomorphs are also isomorphic. Conversely, it is shown that if their holomorphs are isomorphic, then the loops are isotopic. It is shown that a loop is a Smarandache loop if and only if its holomorph is a Smarandache loop. This statement is also shown to be true for some weak Smarandache loops(inverse property, weak inverse property) but false for others(conjugacy closed, Bol, central, extra, Burn, A-, homogeneous) except if their holomorphs are nuclear or central. A necessary and sufficient condition for the Nuclear-holomorph of a Smarandache Bol loop to be a Smarandache Bruck loop is shown. Whence, it is found also to be a Smarandache Kikkawa loop if in addition the loop is a Smarandache A-loop with a centrum holomorph. Under this same necessary and sufficient condition, the Central-holomorph of a Smarandache A-loop is shown to be a Smarandache K-loop.

International Nuclear Information System (INIS)

Surgical resection is the only curative treatment strategy for intrahepatic cholangiocarcinoma (CC). Therefore, accurate staging is essential for appropriate management of patients with CC. We assessed the usefulness of 2-["1"8F]fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) in the staging of CC. We undertook a retrospective review of FDG PET images in 21 patients (10 female, 11 male; mean age 57 years) diagnosed with CC. Ten patients had hilar CC and 11, peripheral CC. Patients underwent abdominal magnetic resonance imaging (MRI) (n=20) and computed tomography (CT) (n=12) for the evaluation of primary tumours, and chest radiography and whole-body bone scintigraphy for work-up of distant metastases. For semi-quantitative analysis, the maximum voxel standardised uptake value (SUV_m_a_x) was obtained from the primary tumour. All peripheral CCs showed intensely increased FDG uptake, and some demonstrated ring-shaped uptake corresponding to peripheral rim enhancement on ...

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Signal-to-noise-ratio (SNR) thresholds for microarray data analysis were experimentally determined with an oligonucleotide array that contained perfect match (PM) and mismatch (MM) probes based upon four genes from Shewanella oneidensis MR-1. A new SNR calculation, called signal to both standard deviations ratio (SSDR) was developed, and evaluated along with other two methods, signal to standard deviation ratio (SSR), and signal to background ratio (SBR). At a low stringency, the thresholds of SSR, SBR, and SSDR were 2.5, 1.60 and 0.80 with oligonucleotide and PCR amplicon as target templates, and 2.0, 1.60 and 0.70 with genomic DNA as target templates. Slightly higher thresholds were obtained at the high stringency condition. The thresholds of SSR and SSDR decreased with an increase in the complexity of targets (e.g., target types), and the presence of background DNA, and a decrease in the composition of targets, while SBR remained unchanged under all situations. The lowest percentage ...

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Background The identification of sequences that control transcription in metazoans is a major goal of genome analysis. In a previous study, we demonstrated that searching for clusters of predicted transcription factor binding sites could discover active regulatory sequences, and identified 37 regions of the Drosophila melanogaster genome with high densities of predicted binding sites for five transcription factors involved in anterior-posterior embryonic patterning. Nine of these clusters overlapped known enhancers. Here, we report the results of in vivo functional analysis of 27 remaining clusters. Results We generated transgenic flies carrying each cluster attached to a basal promoter and reporter gene, and assayed embryos for reporter gene expression. Six clusters are enhancers of adjacent genes: giant, fushi tarazu, odd-skipped, nubbin, squeeze and pdm2; three drive expression in patterns unrelated to those of neighboring genes; the remaining 18 do not appear to have enhancer ...

International Nuclear Information System (INIS)

The role of MRT in the prebiopsy diagnosis of muscular and vascular inflammatory conditions was evaluated prospectively and an optimal method of examination was investigated. 92 patients with a suspected diagnosis of myositis (60 cases) or vasculitis (32 cases) were examined, in each case two extremities were studied using transverse T_1 and T_2 weighted SE sequences and double echo STIR sequences on a 0.5 Tesla (56 patients) or 1.5 Tesla magnet (36 patients; T5/S15 Gyroscan, Philips). The site of the biopsy depended on the MRT findings. In 41 patients the suspected diagnosis was confirmed histologically, in two patients an infective myositis was diagnosed on clinical grounds despite negative histology. MRT demonstrated muscle oedema in 86% of patients. There were negative findings after immuno-suppressive therapy (two patients), in focal myositis (3 out of 4 patients) and in one of 7 patients with untreated vasculitis. Amongst 49 patients in whom the suspected diagnosis could not be ...

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For diagnosis of loosening or infection after implantation of a single-side or double-side total hip endoprosthesis 59 patients being in pain were investigated by a combination of bone scan (Technetium-99m DPD) and leucocyte scan (Indium-111 labelled leucocytes). The correlation between clinical results and scintigraphic findings revealed: bone scintigraphy detects loosening of prostheses with 95% sensitivity (45/47); bone scintigraphy excludes an instable prosthesis with 89% specificity (3/27). 45% of the loosened prostheses revealed an infection (21/47): leucocyte scintigraphy could detect 17 correct positive. Three leucocyte scans of 53 prostheses without clinical signs of infection were false positive. Therefore, leucocyte scintigraphy had a sensitivity of 91% and a specificity of 94% for detecting infection. Bone scintigraphy can detect loosening of prostheses with 93% accuracy, Indium-111 labelled leucocyte scintigraphy can detect infection of the prosthesis ...

International Nuclear Information System (INIS)

The primary aim was to evaluate delayed contrast-enhanced MRI in depicting perineural spread of hilar cholangiocarcinoma (CCC) and consequently to determine the capability of MRI/MRCP for staging CCC. Fifteen patients that underwent MRI/MRCP and surgical treatment were retrospectively included. Two radiologists evaluated MR images to assess delayed periductal enhancement, extent of bile duct stenosis, liver parenchymal and vascular involvement and presence of liver atrophy. An agreement between delayed enhancement of the bile duct walls and perineural neoplastic spread showed a very good correlation factor (0.93). The overall accuracy in detecting biliary neoplastic invasion was higher for delayed T1-weighted images (93.3%) than for the MRCP images (80%), and T1-delayed image increased the MR accuracy in assessing the neoplastic resectability (p < 0.05). MRI correctly predicted vascular involvement in 73% and liver involvement in 80% of the cases. The number of overall correctly ...

CERN Document Server

PAMELA is a satellite borne experiment designed to study with great accuracy cosmic rays of galactic, solar, and trapped nature in a wide energy range protons: 80 MeV-700 GeV, electrons 50 MeV-400 GeV). Main objective is the study of the antimatter component: antiprotons (80 MeV-190 GeV), positrons (50 MeV-270 GeV) and search for antimatter with a precision of the order of 10^-8). The experiment, housed on board the Russian Resurs-DK1 satellite, was launched on June, 15, 2006 in a 350*600 km orbit with an inclination of 70 degrees. The detector is composed of a series of scintillator counters arranged at the extremities of a permanent magnet spectrometer to provide charge, Time-of-Flight and rigidity information. Lepton/hadron identification is performed by a Silicon-Tungsten calorimeter and a Neutron detector placed at the bottom of the device. An Anticounter system is used offline to reject false triggers coming from the satellite. In self-trigger mode the ...

Science.gov (United States)

A novel multilevel hierarchical Kohonen Net (K-Map) for an intrusion detection system is presented. Each level of the hierarchical map is modeled as a simple winner-take-all K-Map. One significant advantage of this multilevel hierarchical K-Map is its computational efficiency. Unlike other statistical anomaly detection methods such as nearest neighbor approach, K-means clustering or probabilistic analysis that employ distance computation in the feature space to identify the outliers, our approach does not involve costly point-to-point computation in organizing the data into clusters. Another advantage is the reduced network size. We use the classification capability of the K-Map on selected dimensions of data set in detecting anomalies. Randomly selected subsets that contain both attacks and normal records from the KDD Cup 1999 benchmark data are used to train the hierarchical net. We use a confidence measure to label the clusters. Then we use the test set from the same KDD Cup 1999 ...

International Nuclear Information System (INIS)

CT scans were performed on 25 patients suspected of sustaining ranal trauma. The utility of CT in both detecting renal damage and appraising the gravity of injuries was assessed. Nowadays, in fact, nephrectomy or reserved for lesions devastanting the kidney parenchyma or rupturing the renal pedicle; so it is very important to identyfy both the purposes of a better planned therapeutic approach. CT does both, being more accurate than urography in the detection of renal fractures, intra or extraparenchymal hematomas and contrast media extravasation. Urography very often shows aspecific lesion patterns and sometimes it is also falsely negative. In the present series CT was more reliable than angiography itself, particulary in the diagnosis of extra-renal hematic collections, contrast media extravasation and injuries to the other abdominal organs. Although CT may arouse the suspicion of and sometimes correctly diagnose vascular lesions, such as renal infarction, ...

International Nuclear Information System (INIS)

To evaluate the diagnostic accuracy, complications, and therapeutic impact of CT-guided percutaneous core biopsies of pulmonary lesions. Material and methods: Seventy-nine patients underwent diagnostic CT-guided percutaneous core biopsies of pulmonary lesions between July 1995 and March 1999. Evaluation included corresponding clinical data, pathologic results, and therapeutic consequences. Results: There were 29 benign and 50 malignant lesions. Percutaneous core biopsy had an overall diagnostic accuracy of 95%. For malignant lesions, core biopsy was positive in 48 patients (sensitivity 96%), and for benign lesions, in 27 (sensitivity 93%). There were no false-positive findings. Pneumothoraces were observed in 19 patients (24%) and 4 of them required a chest drain (5%). There were no hematothoraces or major bleeding complications; however, postinterventional local hemorrhages were observed in 23 patients (29%). No hemoptysis was noted. Conclusion: Percutaneous core ...

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Early recognition of recurrence and work-up of clinically indeterminate lesions may be impaired after reconstruction with silicone implants due to superimposition of the implant or to scarring. This study was undertaken to evaluate the use of contrast-enhanced MRI in patients with silicone implant after breast cancer. Contrast-enhanded MRI was offered to 169 patients. Comparative two- to three-view mammography was also performed in 169 patients, as well as comparative sonography in 144 patients. Conventional imaging and clinical examination detected only 8/13 recurrences, whereas 12/13 were detected by MRI. One recurrence had been visible as a strongly enhancing 2-mm dot in a previous examination (2 years before), but was not called. It was therefore counted as false negative. In addition, multicentricity was detected by MRI alone in two of three cases. MRI correctly diagnosed scar tissue in all cases with indeterminate findings. However, due to ...

Science.gov (United States)

PCR detection of genetic material of the parasites present in faeces may be an alternative for microscopic and serological tests routinely used for diagnosing parasitic enteral infections. However, small amount of target DNA combined with low efficiency of total DNA extraction, and presence of PCR inhibitors in the samples to be amplified, may cause false negative detection results. The aim of this work was to evaluate the impact of DNA isolation procedure used on the amplification of DNA fragments from the genomes of protozoan Cryptosporidium parvum and the nematode Trichinella spiralis. Two methods based on different principles of biological material lysis were evaluated; NucliSENS miniMAG employing simultaneously applied chemical lysis and mechanical disruption or mechanical disruption followed by enzymatic lysis in case of QIAamp DNA Stool Mini Kit. Both of the analyzed systems for nucleic acids purification allowed isolation of DNA from purified ...

International Nuclear Information System (INIS)

Parathyroid imaging based on the principle of differential uptakes of Tc-99m and T1-201 in the anterior neck to localize parathyroid (PT) disease has been reported with widely varying results. To evaluate the usefulness of this method, we have performed PT imaging on 47 patients prior to exploratory surgery for PT disease. Using pinhole collimation and digital acquisition, a 50k count image of the thyroid was obtained 20 minutes after injection of 1mCi99m Tc-pertechnetate. Then a lmCi dose of Tl-201 chloride was injected and a series of images acquired for 30 minutes at 30 sec/image. Raw data was spatially filtered and normalized by summing sufficient T1-201 images to equal the Tc-99m image scale of maximum cts/pixel. Image subtraction (Tl-Tc) gave the final PT image. Of 10 pts who had previous neck exploration, all had PT pathology accurately localized by preoperative scanning (7=single adenoma, 2=single hyperplastic gland, 1=two hyperplastic glands). In two causes distant ectopic ...

International Nuclear Information System (INIS)

Coronary angiography provides anatomical information whereas thellium myocardial scintigraphy measures resistive tissue perfusion. Because of this fundamental difference. The authors question the validity of using coronary angiography as the gold standard to judge thellium myocardial scintigraphy. The authors studied 20 patients undergoing elective percutaneous coronary angioplasty who fulfilled the following criteria: (1) history of chest pain; (2) angiographically significant single vessel disease (>50% stenosis); (3) no prior myocardial infarction. All patients underwent maximal exercise thallium single photon emission computed tomography (T1-SPECT). Tl-SPECT was scored visually according to a 0 to 3 scale (0=absent uptake; 1=markedly decreased uptake; 2=minimally decreased uptake; 3=normal uptake). Translesional gradient and percent stenosis were measured before and after angioplasty. The authors found that significant linear relationship exists between percent stenosis and ...

International Nuclear Information System (INIS)

Purpose: To assess long-term outcomes following percutaneous transluminal angioplasty (PTA) of congenital aortic coarctation in adults.Methods: Seventeen patients underwent PTA for symptomatic adult coarctation of the aorta. Sixteen patients, with a mean age of 28 years (range 15-60 years), were reviewed at a mean interval after angioplasty of 7.3 years (range 1.5-11 years). Assessment included magnetic resonance imaging (MRI), Doppler echocardiography, and clinical examination. Current clinical measurements were compared with pre- and immediate post-angioplasty measurements.Results: At follow-up 16 patients were alive and well. The patient not included in follow-up had undergone surgical repair and excision of the coarctation segment following PTA. Mean brachial systolic blood pressure for the group decreased from 174 mmHg before angioplasty to 130 mmHg at follow-up (p 0.0001). The mean gradient had fallen significantly from 50.9 to 17.8 at follow-up (p = 0.001). The average number of ...

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The purpose was to evaluate low-dose CT colonography without cathartic cleansing in terms of image quality, polyp visualization and patient acceptance. Sixty-one patients scheduled for colonoscopy started a low-fiber diet, lactulose and amidotrizoic-acid for fecal tagging 2 days prior to the CT scan (standard dose, 5.8-8.2 mSv). The original raw data of 51 patients were modified and reconstructed at simulated 2.3 and 0.7 mSv levels. Two observers evaluated the standard dose scan regarding image quality and polyps. A third evaluated the presence of polyps at all three mSv levels in a blinded prospective way. All observers were blinded to the reference standard: colonoscopy. At three times patients were given questionnaires relating to their experiences and preference. Image quality was sufficient in all patients, but significantly lower in the cecum, sigmoid and rectum. The two observers correctly identified respectively 10/15 (67%) and 9/15 (60%) polyps {>=}10 mm, with 5 and 8 ...

International Nuclear Information System (INIS)

In 65 adult rabbits of both sexes (2.5 to 6 kg) the following salvaging procedures were performed after simulated trauma: (1) Continuous suture line; (2) closure with fibrin sealant after temporary clamping; (3) hemisplenectomy with omental wrap; (4) suture fixation of fragments and slices of spleen tissue to the peritoneum; (5) suture fixation of spleen fragments to the omentum; (6) extraperitoneal subcutaneous transposition of spleen cubes. In addition, the likelihood of spontaneous splenosis was examined in a preliminary study involving 5 animals by introducing unattached spleen meal and fragments. Scanning was repeated 4 to 12 weeks postoperatively. The functional competence of minor parenchymal islands was also investigated with well counter measurements of organ and muscle tissue homogenates. Spontaneous splenosis after abdominal injuries was not found to be the rule. Salvaging procedures at the natural vascular hilus by sutures, fibrin sealant and hemisplenectomy produced ...

Energy Technology Data Exchange (ETDEWEB)

In recent years the 'Nowcasting Wake Vortex Impact Variables' model NOWVIV has been developed at the Deutsches Zentrum fuer Luft- und Raumfahrt, DLR, to forecast weather parameters in airport environments. The German Meteorological Service, DWD, employs his COSMO-DE model (COnsortium for Small scale Modelling-DEutschland) for operational forecasts in Germany. A systematic comparison of model output from NOWVIV and a derivate of COSMO-DE, named COSMO-FRA, is presented. Both models are centred at Frankfurt Airport with horizontal resolutions of 2.1 km and 2.8 km, respectively. In the DLR Project Wetter and Fliegen the COSMO-FRA model will replace the NOWVIV model and become a key component in the future rapid update cycle for adverse weather predictions at the airports of Frankfurt and Munich. The forecast vertical profiles of runway crosswind, head/tail wind, temperature, and turbulent kinetic energy (TKE) are validated against Wind and Temperature Radar (WTR/RASS) ...

Energy Technology Data Exchange (ETDEWEB)

To establish the optimum barium-based reduced-laxative tagging regimen prior to CT colonography (CTC). Ninety-five subjects underwent reduced-laxative (13 g senna/18 g magnesium citrate) CTC prior to same-day colonoscopy and were randomised to one of four tagging regimens using 20 ml 40%w/v barium sulphate: regimen A: four doses, B: three doses, C: three doses plus 220 ml 2.1% barium sulphate, or D: three doses plus 15 ml diatriazoate megluamine. Patient experience was assessed immediately after CTC and 1 week later. Two radiologists graded residual stool (1: none/scattered to 4: >50% circumference) and tagging efficacy for stool (1: untagged to 5: 100% tagged) and fluid (1: untagged, 2: layered, 3: tagged), noting the HU of tagged fluid. Preparation was good (76-94% segments graded 1), although best for regimen D (P = 0.02). Across all regimens, stool tagging quality was high (mean 3.7-4.5) and not significantly different among regimens. The HU of layered tagged fluid was ...

Energy Technology Data Exchange (ETDEWEB)

The high spatial resolution of state-of-the-art commercial satellite imagery provides a good basis for recognising and monitoring even small-scale structural changes within nuclear facilities and for planning of routine and/or challenge inspections of nuclear sites. Despite the advantages of the improved spatial resolution some problems exist that may make the interpretation of the changes more difficult: Firstly, the results of the change analysis can be very complex and unclear at a glance. Secondly, shadow formation and off-nadir images due to different sensor and solar conditions at the acquisition times can cause false signals or overlap real changes. In view to the fast-growing amount of data from different sensor types there are then some requirements of an effective change detection procedure for safeguards purposes: i. The techniques involved should possess a certain amount of robustness in terms of small misregistration errors, different atmospheric ...

Energy Technology Data Exchange (ETDEWEB)

Acute thoracic aortic injuries account for up to 10-20% of fatalities in high-speed deceleration road accidents and have an estimated immediate fatality rate of 80-90%. Untreated survivors to acute trauma (10-20%) have a dismal prognosis: 30% of them die within 6 hours, 40-50% die within 24 hours, and 90% within 4 months. It was investigated the diagnostic accuracy of Helical Computed Tomography (Helical CT) in acute traumatic injuries of the thoracic aorta, and the role of this technique in the diagnostic management of trauma patients with a strong suspicion of aortic rupture. It was compared retrospectively the chest Helical CT findings of 256 trauma patients examined June 1995 through August 1999. Chest Helical CT examinations were performed according to trauma score, to associated traumatic lesions and to plain chest radiographic findings. All the examinations were performed with no intravenous contrast agent administration and the pitch 2 technique. After a previous baseline ...

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