Energy Technology Data Exchange (ETDEWEB)

The covariant quark model is shown to allow a phenomenological description of the neutron electric form factor, G{sub E}{sup n}(Q{sup 2}), in the impulse approximation, provided that the wave function contains minor ({approx}3%) admixtures of the lowest energy sea-quark configurations. While that form factor is not very sensitive to whether the q{sup -} in the qqqqq{sup -} component is in the P-state or in the S-state, the calculated nucleon magnetic form factors are much closer to the empirical values in the case of the former configuration. In the case of the electric form factor of the proton, G{sub E}{sup p}(Q{sup 2}) a zero appears in the impulse approximation close to 10 GeV{sup 2}, when the q{sup -} is in the P-state. That configuration, which may be interpreted as a pion loop ('cloud') fluctuation, also leads to a clearly better ...

Science.gov (United States)

This article reviews antisocial personality disorder, psychopathy, and violence and develops a three factor model of personality traits. Then a discussion of related personality disorders precedes the development of a categorical two factor model of impulsive versus remorseless violence. A paradigm of proactive, medical, and school based early intervention and prevention is advocated as a useful addition to the reactive detention of criminal justice. Integration of psychological tests, neuroimaging, and genomic data in early childhood and school based intervention strategies to prevent the development of conduct disorder and attenuate criminal propensity inform this approach. PMID:20422651

International Nuclear Information System (INIS)

The wide-angle spectra of the 134-MeV (p,n) reaction on "4"8Ca, "5"4Fe, "8"8Sr, and "2"0"8Pb are each dominated by the excitation of a single state at low excitation energy. These excitations correspond to the ''0h#omega#'' stretched states and are seen to be fragmented much less than ''1h#omega#'' stretched states in medium- and heavy-mass nuclei. The normalization factors required for comparison with distorted-wave impulse-approximation calculations are >0.50 and indicate that these are the purest particle-hole states known in these nuclei.

KoreaScience (Korea)

Full Text Available

UK PubMed Central (United Kingdom)

AbstractThe tick-borne protozoan parasite Theileria annulata causes a debilitating disease of cattle called Tropical Theileriosis. The parasite predominantly invades...Full Text Available

UK PubMed Central (United Kingdom)

It has become increasing clear that alterations in cellular metabolism have a key role in the generation and maintenance of cancer. Some of the metabolic changes can be attributed to the activation...Full Text Available

UK PubMed Central (United Kingdom)

Exposure of Mycobacterium tuberculosis to hypoxia is known to alter the expression of many genes, including ones thought to be involved in latency, via the transcription factor DevR...Full Text Available

UK PubMed Central (United Kingdom)

The state of chromatin (the packaging of DNA in eukaryotes) has long been recognized to have major effects on levels of gene expression, and numerous chromatin-altering strategies—including...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The Integrated Solar Upper Stage (ISUS) Program at the USAF Phillips Laboratory is directed at demonstrating a solar bimodal power and propulsion system for military applications. Trades were performed to examine the potential performance of the ISUS stage combined with the proposed LLV-3 launch vehicle. Variation in ISUS thermal power directly affects the trip time from LEO to GEO. These variations can be altered by changing average propellant temperature raising or lowering the average specific impulse. If the ISUS system is sized for the spacecraft`s electrical power requirements, this can result in long trip times for high mass satellites with low electrical power requirements. The ISUS can be sized, however, for a suitable thermal power to allow more rapid trip times with minimum impact on delivered mass. Such a system can place significantly more payload in GEO than a solid chemical stage. The mass advantages of the ISUS increase as ...

International Nuclear Information System (INIS)

We have measured the transverse asymmetry A_T_"' in the quasielastic "3He-vector(e-vector,e"') process with high precision at Q"2 values from 0.1 to 0.6 (GeV/c)"2. The neutron magnetic form factor G_M"n was extracted at Q"2 values of 0.1 and 0.2 (GeV/c)"2 using a nonrelativistic Faddeev calculation which includes both final-state interactions (FSI) and meson-exchange currents (MEC). Theoretical uncertainties due to the FSI and MEC effects were constrained with a precision measurement of the spin-dependent asymmetry in the threshold region of "3He-vector(e-vector,e"'). We also extracted the neutron magnetic form factor G_M"n at Q"2 values of 0.3 to 0.6 (GeV/c)"2 based on plane wave impulse approximation calculations.

UK PubMed Central (United Kingdom)

In monocytes, sulfatide, a lipid from Mycobacterium tuberculosis, blocked priming for enhanced release of superoxide (O2-) by the macrophage activating factors lipopolysaccharide, gamma interferon,...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Anxiety disorders are a highly prevalent and disabling class of psychiatric disorders. This review focuses on new directions in neurobiological research and implications for the development of novel psychopharmacological treatments. Neuroanatomical and neuroimaging research in anxiety disorders has centered on the role of the amygdala, reciprocal connections between the amygdala and the prefrontal cortex, and, most recently, alterations in interoceptive processing by the anterior insula. Anxiety disorders are characterized by alterations in a diverse range of neurochemical systems, suggesting ample novel targets for drug therapies. Corticotropin-releasing factor (CRF) concentrations are elevated in a subset of anxiety disorders, which suggests the potential utility of CRF receptor antagoni...

International Nuclear Information System (INIS)

The stages of processes leading to radiation damage are studied, as well as, the direct and indirect mechanics of its production. The radiation effects on nucleic acid and protein macro moleculas are treated. The physical and chemical factors that modify radiosensibility are analysed, in particular the oxygen effects, the sensibilization by analogues of nitrogen bases, post-effects, chemical protection and inherent cell factors. Consideration is given to restoration processes by excision of injured fragments, the bloching of the excision restoration processes, the restoration of lesions caused by ionizing radiations and to the restoration by genetic recombination. Referring to somatic effects of radiation, the early ones and the acute syndrome of radiation are discussed. The difference of radiosensibility observed in mammalian cells and main observable alterations in tissues and organs are commented. Referring to delayed ...

Science.gov (United States)

Attention deficit hyperactivity disorder (ADHD) is one of the most common behavioral disorders in children. Symptoms of ADHD include hyperactivity, low frustration tolerance, impulsivity, and inattention. While the biological pathways leading to ADHD are not clearly delineated, a number of genetic and environmental risk factors for the disorder are recognized. In the early 1970s, research conducted by Dr. Benjamin Feingold found that when hyperactive children were given a diet free of artificial food additives and dyes, symptoms of hyperactivity were reduced. While some clinical studies supported these findings, more rigorous empirical studies conducted over the next 20 years were less positive. As a result, research on the role of food additives in contributing to ADHD waned. In recent years, however, interest in this area has revived. In response to more recent research and public petitions, in December 2009 the British government requested ...

UK PubMed Central (United Kingdom)

Whether the lusitropic potential of short-term exercise in aged rats is linked to an augmentation in the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and an alteration in the...Full Text Available

International Nuclear Information System (INIS)

Scattered radiation generated in patient and imaging system has to be considered when quality-assurance tests involve dose detection or image-quality estimations. Measurement of automatic-exposure control dose can be altered by backscattering from intensifying screens of more than 10% and the equipment transmission factor can be overestimated up to a factor of 10 when only primary radiation is used. The sensitivity of intensifying screens depends on the angle of incidence of the radiation and so primary and scattered radiation are detected differently. The quality-control aspects of anti-scatter grids are discussed. (author).

Energy Technology Data Exchange (ETDEWEB)

In this paper, we consider the prey-dependent consumption predator-prey (natural enemy-pest) models with age structure for the predator, immature and mature natural enemies are released and pesticide is applied impulsively. We prove that, when the impulsive period is no longer than some threshold, the pest-eradication solution is globally asymptotically stable, or say, the pest population can be eradicated totally. But from the point of ecological balance and saving resources, we only need to control the pest population under the economic threshold level instead of eradicating it totally, so we further prove that, when the impulsive period is longer than the threshold, pest population and natural enemy population can coexist, i.e., the system is uniformly permanent. Considering population communities always are imbedded in periodically varying environments, and the parameters in ecosystem models may oscillate simultaneously ...

British Library Electronic Table of Contents (United Kingdom)

Objectives: Intra-operative cisplatin-based intra-peritoneal chemotherapy (IPC) may alter renal function in patients with advanced ovarian cancer. The aim of this study was to describe postoperative alteration of renal function after cisplatin-based IPC and to identify risk factors for moderate to severe acute renal failure. Study design: This prospective observational study was carried out on 77 consecutive patients who underwent cisplatin-based IPC procedures, with (n=23) or without (n=54) intra-peritoneal epinephrine, for advanced ovarian cancer. Postoperative renal function was assessed using serial serum creatinine measurements and was based on serum creatinine changes from pre-operative values, according to the risk, injury, failure, loss, end-stage kidney disease (RIFLE) classificat...

Energy Technology Data Exchange (ETDEWEB)

In this paper, we investigate the dynamic behaviors of a Holling II two-prey one-predator system with impulsive effect concerning biological control and chemical control strategies-periodic releasing natural enemies and spraying pesticide (or harvesting pests) at fixed time. By using the Floquet theory of linear periodic impulsive equation and small-amplitude perturbation we show that there exists a globally asymptotically stable two-prey eradication periodic solution when the impulsive period is less than some critical value. Further, we prove that the system is permanent if the impulsive period is larger than some critical value, and meanwhile the conditions for the extinction of one of the two prey and permanence of the remaining two species are given. Finally, numerical simulation shows that there exists a stable positive periodic solution with a maximum value no larger than a given level. Thus, we ...

Energy Technology Data Exchange (ETDEWEB)

16 papers are presented covering: remote sensing - an aid to environment management; remote sensing application; monitoring environmental changes over iron ore mining areas; monitoring and management of environmental degradation due to geological factors; use of Landsat multispectral scanner data in environmental monitoring; geotechnical engineering problems with abandoned limestone mines; photogrammetric monitoring of mining environment; slope monitoring in open cast mines using close range remote sensing method; geobotanical remote sensing and mineral prospecting; geographical information in study of geo-environment through remote sensing; and alteration mapping in cuprite mining district.

British Library Electronic Table of Contents (United Kingdom)

Recent studies have shown Y chromosome microdeletions associated with male infertility. The factors responsible for Y chromosome microdeletions in spermatozoa remain unresolved. However, the environmental pollutants are known to damage DNA in differentiating and maturing germ cells in the male reproductive tract. Therefore, the aim of this study was to investigate the effects of seminal hexachlorocyclohexane (HCH) and its isomers, an environmental pollutant, in 50 fertile and 50 infertile males in relation to semen quality and the incidence of Y chromosome microdeletion in azoospermic factor (AZF) region. As compared to control, an increased HCH level and significantly decreased semen quality were observed in the infertile males. A positive significant association was found between sperm c...

CERN Document Server

Change management

Energy Technology Data Exchange (ETDEWEB)

According to biological and chemical control strategy for pest control, we investigate the dynamics of a predator-prey food chain with impulsive effect, periodic releasing natural enemies and spraying pesticide at different fixed times, by using impulsive differential equation. Choose pest birth rate r{sub 2} as control parameter, we show that there exists a stable pest-eradication periodic solution when r{sub 2} is less than some critical value r{sub 2}* and the system is permanence when r{sub 2} is larger than the critical value r{sub 2}*. By use of standard techniques of bifurcation theory, we prove that above this threshold there are periodic oscillations in prey, middle-predator and top predator. Furthermore, bifurcation diagrams have shown that there exists complexity for the pulsed system including periodic doubling cascade.

Energy Technology Data Exchange (ETDEWEB)

The distribution of i.v. administered lead (/sup 203/Pb-acetate; 50 nmol/kg b.w.) was studied by means of autoradiography and impulse counting in pregnant C57BL mice (day 18) treated orally with dithiocarbamates. Diethyldithiocarbamate (DEDTC), disulfuram or thiram (2 X 1) mmol/kg b.w.) or vehicle (gelatine) alone, was given by gavage 2 h before and immediately after the injection of lead. All three dithiocarbamates, especially thiram, changed the distribution pattern of lead. Thiram and DEDTC had the greatest effect at 4 h after lead administration, disulfiram at 24 h. In the mother, most notably the brain concentration increased (70-fold for thiram at 4 h) while that of erythrocytes and skeleton decreased (50- and 4-fold, respectively). The total fetal concentration unexpectedly showed only a moderate increase (proportional 2-fold for thiram), which may be due partly to the low maternal plasma lead concentration. The partition within the fetal tissues was, ...

Energy Technology Data Exchange (ETDEWEB)

Papers are presented in the areas of: Medical Technologies; Non-Destructive Evaluation; Applications of Signal/Image Processing; Laser Guide Star and Adaptive Optics; Computational Electromagnetic, Acoustics and Optics; Micro-Impulse Radar Processing; Optical Applications; TANGO Space Shuttle.

UK PubMed Central (United Kingdom)

PURPOSE:Two different regimens of SWL delivery for treating urinary stones were compared.METHODS:Patients with urinary stones were randomly divided...Full Text Available

International Nuclear Information System (INIS)

In the present paper we propose a model of physical phenomena behind the front face of the electrodes in an impulse plasma accelerator. The model is based on the results of recent experimental observations and measurements. It correlates plasma dynamics with mechanism of phenomena in a column of pinching plasma. On the contrary to the previous model the current one suggests the series of relatively short pulses of metallic ions from the erosion of electrode material. Till now the pinch was treated rather as a nearly continuous source of metallic plasma, feeding the process with ions from the erosion of electrode material. (author)

International Nuclear Information System (INIS)

Many assays for oncogenic transformation have been developed ranging from those in established rodent cell lines where morphological alteration is scored, to those in human cells growing in nude mice where tumor invasiveness is scored. In general, systems that are most quantitaive are also the least relevant in terms of human carcinogenesis and human risk estimation. The development of cell culture systems has made it possible to assess at the cellular level the oncogenic potential of a variety of chemical, physical and viral agents. Cell culture systems afford the opportunity to identify factors and conditions that may prevent or enhance cellular transformation by radiation and chemicals. Permissive and protective factors in radiation-induced transformation include thyroid hormone and the tumor promoter TPA that increase the transformation incidence for a given dose of radiation, and retinoids, selenium, vitamin E, and ...

British Library Electronic Table of Contents (United Kingdom)

Abstract Capillary permeability is a tightly regulated feature of microcirculation in all organ beds. In sepsis, this feature is fundamentally altered. We have previously reported elevated levels of angiopoietin-2 in patients with septic shock, and have investigated tumor necrosis factor (TNF)-related and weak inducer of apoptosis (TWEAK), which mediates both angiogenesis and inflammation, in those patients. Enzyme-linked immunoassay was used to measure serum TWEAK levels in 20 patients with septic shock, all of whom were treated by direct hemoperfusion with a polymyxin B-immobilized fiber column (DHP-PMX), and in 20 non-septic controls. The TWEAK levels were higher in patients with septic shock (192.8--230.5-pg/mL) than in controls (84.1--28.7-pg/mL, P-=-0.043). Between 11 survivors and 1...

British Library Electronic Table of Contents (United Kingdom)

Detailed geothermal studies of deep drill holes provide insights to heat transfer processes in the crust, and allow separation of different factors involved, such as palaeoclimatic and structural conductive effects as well as advective fluid flow effects. We present high resolution geothermal results of the 2516m deep Outokumpu Deep Drill Hole in eastern Finland drilled in 2004-2005 into a Palaeoproterozoic formation with metasedimentary rocks, ophiolite-derived altered ultramafic rocks and pegmatitic granite. The down-hole temperatures have been logged five times after end of drilling and extend to day 948 after drilling. The hole is completely cored (79% core coverage) and thermal conductivity measurements were done at 1m intervals. The geothermal results on temperature gradient, thermal...

British Library Electronic Table of Contents (United Kingdom)

Background The purpose of this study was (a) to evaluate the association between cigarette smoking and the prevalence of distal colorectal polyps and adenocarcinoma and (b) to analyse genetic alterations representing different molecular pathways of the colorectal carcinogenesis. Methods A total of 623 asymptomatic male (mean age: 53 years; 50?65) car factory workers were included. Information on smoking habits and other lifestyle factors were collected followed by a 60 cm colonoscopy. APC and KRAS mutations and microsatellite status were determined in colorectal lesions (colorectal carcinoma (CRC), hyperplastic (HP) and adenomatous polyps (AP)). Data were analysed using unconditional multiple logistic regression models. Results Smokers had a higher prevalence of AP (OR 2.1; 95% CI 1.2?3.6;...

Energy Technology Data Exchange (ETDEWEB)

The leached glass is subject to leachant attack and results in surface layer alteration which greatly affects the corrosion progress of glass forms. This work studied the composition change, precipitation, pitting corrosion as well as surface layer break and spallation of the leached glass forms. 6 conclusions can be made: 1. The extent of surface layer alteration is related to many factors such as temperature, pH, leachant chemistry, flow rate and leach duration, etc. 2. The alkali element Na is seriously depleted and the elements like U.Ti,Fe, Ca and Mg are enriched in the surface layer. The influence of media has such order: Fe{sub 2}O{sub 3} > Na-bentonite > Zeolite. 3. The precipitate formed in leach test for 56 days at 90 {infinity}C is mostly amorphous, but after 91 days has crystallized. There is K - Ca - Al - Si crystal,the amount of Al, K and Si is increasing, but the amount of Ca is decreasing along ...

International Nuclear Information System (INIS)

Published in summary form only.

British Library Electronic Table of Contents (United Kingdom)

Cholestatic liver injury induced by alpha-naphthylisothiocyanate (ANIT) is provoked by injury to intrahepatic bile ducts and the progression of hepatic necrosis requires the procoagulant protein tissue factor (TF) and extrahepatic cells including neutrophils. Recent studies have shown that myeloid cell TF contributes to neutrophil activation. We tested the hypothesis that myeloid cell TF contributes to neutrophil activation in ANIT-treated mice. TF activity in liver homogenates increased significantly in TF^f^l^o^x^/^f^l^o^x mice treated with ANIT, but not in TF^f^l^o^x^/^f^l^o^x/LysMCre mice (TFD^M^y^e^l^o^i^d mice), which have reduced TF expression in monocytes/macrophages and neutrophils. Myeloid cell-specific TF deficiency did not alter expression of the chemokines KC or MIP-2 but redu...

Science.gov (United States)

Endoreduplication represents a cell cycle variant during which multiple rounds of DNA replication occur without subsequent chromosome separation and cytokinesis, resulting into a cellular increase of the DNA content. Although the DNA ploidy level of cells is controlled by external stimuli such as light, currently limited knowledge is available on how environmental signals regulate the endoreduplication cycle at the molecular level. Previously, we have demonstrated that the conversion from the mitotic cell cycle into an endoreduplication cycle is mediated by the atypical E2F transcription factor DEL1 that operates as a repressor of endocycle onset. Here, we identified DEL1 as a transcriptional target of the classical E2Fb and E2Fc transcription factors that antagonistically control DEL1 transcript levels through competition for a single E2F cis-acting binding site. Correspondingly with the reported opposite effect of light on the E2Fb and E2Fc ...

Energy Technology Data Exchange (ETDEWEB)

The peak flux relationship between hard X-rays and microwaves from solar flares is studied using about 400 events simultaneously recorded with the hard X-ray burst spectrometer on the SMM satellite and the Nobeyama 17 GHz radiometer. The data indicate that the hard X-ray and microwave peak fluxes correlate best for X-ray energies of less than about 80 keV for impulsive flares and greater than about 360 keV for extended flares. By postulating that electrons responsible for microwave emission at 17 GHz are those emitting hard X-rays at these photon energies, it is concluded that: (1) in impulsive flares, microwaves at about 20 GHz are emitted mainly by electrons of less than about 200 keV from a layer through which the electrons stream down into the thick-target hard X-ray source; and (2) in extended flares, microwaves are emitted mainly by MeV electrons trapped in a coronal loop or loops. 59 references.

Energy Technology Data Exchange (ETDEWEB)

Large-scale three dimensional molecular dynamics simulations of hopper flow are presented. The flow rate of the system is controlled by the width of the aperture at the bottom. As the steady-state flow rate is reduced, the force distribution P(f) changes only slightly, while there is a large change in the impulse distribution P(i). In both cases, the distributions show an increase in small forces or impulses as the systems approach jamming, the opposite of that seen in previous Lennard-Jones simulations. This occurs dynamically as well for a hopper that transitions from a flowing to a jammed state over time. The final jammed P(f) is quite distinct from a poured packing P(f) in the same geometry. The change in P(i) is a much stronger indicator of the approach to jamming. The formation of a peak or plateau in P(f) at the average force is not a general feature of the approach to jamming.

International Nuclear Information System (INIS)

Soya- and oats-lipoxygenase (E.C. 1.13.1.13) are incubated by "1"4C-marked linoleic acid. The volatile aldehydes arising thereby are isolated. The activity of the components separated by gaschromatography is written down by a printing indicator and the impulses/min are registered and printed out by a ratemeter. Thus the aldehydes which are produced by the enzymatic oxydation with lipoxygenase from the molecule of the linoleic acid can be determined. The composition of the mixture of aldehydes is calculated in mol-% from the measured impulses for peak. A possible origin of pathway is indicated for the main reaction products hexanal (soyalipoxygenase) and non-trans-2-enal (oats-lipoxygenase). (orig.).

KoreaScience (Korea)

Full Text Available

KoreaScience (Korea)

Full Text Available

Energy Technology Data Exchange (ETDEWEB)

In spite of the fact that market requirements for new plants continue to be restricted, steam turbine technology and operation engineers have left nothing undone to improve products and operating characteristics. They are generally guided by the principle of optimum economic power supplies but lowest pollution. The new eastern markets are expected to give new impulses to steam turbine design. Cogeneration is of special future importance. (orig.).

Energy Technology Data Exchange (ETDEWEB)

The transfer function concept is well known as an additional method to evaluate the impulse test of power transformers in the test laboratory. Another application for the transfer function method is monitoring of transformers in service. Thereby, Off-line and On-line monitoring can be realized. Both kinds of monitoring are demonstrated with on-site measurements on a power transformer in service.

Energy Technology Data Exchange (ETDEWEB)

Proton induced X-ray and {gamma}-ray emission (PIXE/PIGE) have been used to analyze major and trace elements in a suite of 140 core samples from around of the Jim`s Find South gold anomaly in the Tanami desert, located in heavily weathered terrain. Simultaneous analyses were obtained for 30 elements, ranging in atomic number from {sup 3}Li to {sup 90}Th. The method was chosen because of its speed and the wide range of determination, its flexibility, precision and low detection limits. The regolith powder samples were treated by hot aqua regia before making them into pills. The PIXE/PIGE data of the acid insoluble residue give three factor analysis clusters. The first cluster comprises the elements F, Al, K, V, Mn, Fe, Ga, Rb, W and Au and is essentially related to sericitic wallrock alteration. The second cluster consists of Ti, As, Y, Zr, and Nb and is largely related to resistant minerals. The third cluster consists of Na, Ca and Sr and is ...

International Nuclear Information System (INIS)

Central Nervous System (CNS) involvement, whether primary by the Human Immunodeficiency Virus - HIV - itself, or secondary (toxoplasmosis or lymphoma) is remarkably frequent in AIDS, in 40 to 70% of cases, depending upon the author. In order to study the natural history of this illness, a cohort of 25 asymptomatic seropositive patients have been established. Every 6 months these patients undergo biological and clinical examinations, as well as Magnetic Resonance brain scans. After two examinations at a 6 month's interval, the first results are reported. Out of these 25 cases, 9 present anomalies: One patient with diffuse cerebral atrophy and 8 others with high signal intensity areas on T2 weighted sequences, like those of the Multiple Sclerosis. No relationship could be demonstrated between the existence of these lesions and various criteria such as age, sex, risk factors and T4 cells count. The nature of these lesions is not lear. They certainly indicate early ...

International Nuclear Information System (INIS)

Diagnostic capability of Fuji Computed Radiography (FCR) of the chest was compared to the conventional radiography (CoR) using regular film-screen system. FCR utilizers imaging plates of scanning laser stimulated luminescence. Visibility of 14 structures of the chest radiography was evaluated by 3 radiologists in 100 pairs of FCR and CoR which were taken at the same time with the same exposure factors. FCR was superior to CoR especially in observation of the mediastinum and areas behind the heart and diaphragm. The minor fissure was better seen on CoR. Superiority of FCR to CoR was thought to be mainly due to the processed image of FCR, and the so-called normal image of FCR had little diagnostic advantage. Simulated abnormal densities: nodular, alveolar, and interstitial densities with a chest phantom, were made, and detectability of alteration of these densities on FCR and CoR was evaluated by 19 radiologists, using ROC curve analysis. FCR and ...

Energy Technology Data Exchange (ETDEWEB)

The interpretation of soil amelioration experiments with peanuts is made difficult by the unpredictibility of the crop and by the many factors altered when ameliorating acid soils. The present study was conducted to investigate the effects of lime and gypsum applications on peanut kernel yield via the three first order yield components, pods per ha, kernels per pod, and kernel mass. On an acid medium sandy loam soil (typic Plinthustult), liming resulted in a highly significant kernel yield increase of 117% whereas gypsum applications were of no significant benefit. As indicated by path coefficient analysis, an increase in the number of pods per ha was markedly more important in increasing yield than an increase in either the number of kernels per pod or kernel mass. Furthermore, exch. Al was found to be particularly detrimental to pod number. It was postulated that poor peanut yields resulting from acid soil infertility were mainly due to the ...

Science.gov (United States)

Recent studies have shown Y chromosome microdeletions associated with male infertility. The factors responsible for Y chromosome microdeletions in spermatozoa remain unresolved. However, the environmental pollutants are known to damage DNA in differentiating and maturing germ cells in the male reproductive tract. Therefore, the aim of this study was to investigate the effects of seminal hexachlorocyclohexane (HCH) and its isomers, an environmental pollutant, in 50 fertile and 50 infertile males in relation to semen quality and the incidence of Y chromosome microdeletion in azoospermic factor (AZF) region. As compared to control, an increased HCH level and significantly decreased semen quality were observed in the infertile males. A positive significant association was found between sperm count with alpha-HCH and beta-HCH in the infertile males. A negative significant association was observed between sperm counts with gamma-HCH in asthenospermia ...

Energy Technology Data Exchange (ETDEWEB)

The most important kaolin deposits from Campo Alegre region (S C) were formed by the conjunction of at least one hydrothermal phase followed by many others weathering, supergenic, phases. Possibly deposits formed by only one of these processes exist, but these deposits shall be small and smaller than those mined today. Besides kaolinization, illitization/muscovitization and silicification, hydrothermalism also generated pyritized and propilitized zones, with quartz + chlorite. Together, hipogenic alterations related to kaolin deposits are very similar to alterations of high sulfidation epigenetic volcanogenic gold deposits. Most part of the biggest kaolin mines from the southern part of Campo Alegre Basin are distributed along a 13 Km long and 0,5 Km width bent zone that is parallel to structural alignments that point out the eastern Basin border. This zone was originated by deformation that has inclined and broken rocks, generating a fault ...

UK PubMed Central (United Kingdom)

Neonatal bacterial infection in rats alters the responses to a variety of subsequent challenges later in life. Here we explored the effects of neonatal bacterial infection on a subsequent drug...Full Text Available

UK PubMed Central (United Kingdom)

The incidence of melanoma is increasing more than any other cancer, and knowledge of its genetic alterations is limited. To systematically analyze such alterations, we performed whole-exome...Full Text Available

UK PubMed Central (United Kingdom)

Alterations in basement membrane components, notably proteoglycans, in a rat model of polycystic kidney disease have been investigated. Rats were fed phenol II (2-amino-4-hydroxyphenyl-5-phenyl thiazole)...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Step-scan Fourier transform infrared spectroscopy in conjunction with impulse stress on polymer films has been used to monitor dynamic rheological responses in real time. A novel piezo-electrically-driven polymer microrheometer was employed to apply repetitive impulses to the polymer sample while time-domain spectra were recorded. Recent results include the study of both semi-crystalline polymers such as isotactic polypropylene (iPP) and elastomers such as Estane polyester/polyurethane copolymer and Kraton tri-block copolymer. The spectral changes of iPP are consistent with frequency-domain results. For iPP at room temperature, large differences in the response times of different absorption bands are not seen. However, the orientation response of the CH{sub 3} rocking mode is slightly slower than the responses of the backbone modes. To the authors` knowledge, this is the first reported successful step-scan FTIR time-domain dynamic polymer ...

Energy Technology Data Exchange (ETDEWEB)

Pollution abatement measures against impulsive low frequency noises including mine blasting noise require precise measurement of sound waveforms, but no instruments have been designed for that purpose, nor commercially available. This paper describes investigations on such instruments as noise level meters currently available commercially on their instrumental characteristics using indoor experiments and field measurements. The following matters were clarified: An instrument combining a microphone with an amplifier can not determine the response from the measuring system from the respective frequency characteristics alone, and requires a discussion on the overall response from the measuring system. A preferred noise level meter would be an instrument that has the lower limit for the frequency characteristics of the microphone extended to several hertz, and measures noises without passing through a filter to interrupt frequencies lower than 20 Hz. A mine blasting ...

CERN Document Server

Motivated by the numerical investigations of Laval, Dubrulle & Nazarenko (1999), we develop a quasilinear theory of the 2D Euler equation and derive an integro-differential equation for the evolution of the coarse-grained vorticity. This equation respects all the invariance properties of the Euler equation and conserves angular momentum in a circular domain and linear impulse in a channel (as well as in an infinite domain). The explicit energy is not rigorously conserved as it is partly transfered into fine-grained fluctuations but the total energy is conserved. We prove a H-theorem for the Fermi-Dirac entropy and make the connection with statistical theories of 2D turbulence.

Energy Technology Data Exchange (ETDEWEB)

Because every cell within the body has the same genetic information, a significant problem in biology is to understand how cells within a tissue express genes selectively. A sophisticated network of physical and biochemical signals converge in a highly orchestrated manner to bring about the exquisite regulation that governs gene expression in diverse tissues. Thus, the ultimate decision of a cell to proliferate, express tissue-specific genes, or apoptose must be a coordinated response to its adhesive, growth factor, and hormonal milieu. The unifying hypothesis examined in this overview is that the unit of function in higher organisms is neither the genome nor the cell alone but the complex, three-dimensional tissue. This is because there are bidirectional connections between the components of the cellular microenvironment (growth factors, hormones, and extracellular matrix) and the nucl2048 These connections are made via membrane-bound ...

International Nuclear Information System (INIS)

The diffusion coefficients (De) in bentonite were measured to understand and quantify the influence of groundwater chemistry such as ionic strength and to quantify the alteration of smectite mineralogical transformations. (author)

UK PubMed Central (United Kingdom)

Myriad genetic and epigenetic alterations are required to drive normal cells toward malignant transformation. These somatic events commandeer many signaling pathways that cooperate to endow aspiring...Full Text Available

UK PubMed Central (United Kingdom)

Conditions were found in which Chlamydomonas reinhardi exhibits a circadian alteration of its cell surface, measured as ability to stick to glass. Under these same conditions the cells...Full Text Available

UK PubMed Central (United Kingdom)

Age-related alterations in the cellular composition of the B lineage are a major cause of the poor antibody response to vaccination and to infectious agents among the elderly population. The mechanisms...Full Text Available

UK PubMed Central (United Kingdom)

The success of monoclonal antibodies in clinical practice is dependent on good design. Finding a suitable target is the most important part as other properties of the antibody can be altered by genetic...Full Text Available

Science.gov (United States)

... objective of this research work were to 1 ... function of experimentally manipulated dogs to define ... Escherichia coli; Sepsis; Military medicine; Medical ...

UK PubMed Central (United Kingdom)

According to classical concepts of physiologic control, healthy systems are self-regulated to reduce variability and maintain physiologic constancy. Contrary to the predictions of homeostasis, however,...Full Text Available

UK PubMed Central (United Kingdom)

Copper deficiency is associated with impaired brain development and mitochondrial dysfunction. Perinatal copper deficiency was produced in Holtzman rats. In vivo proton NMR...Full Text Available

UK PubMed Central (United Kingdom)

Context: Some studies suggest altered pituitary functioning and TSH production with aging.Objective: Our objective was to test the hypothesis that less TSH production...Full Text Available

UK PubMed Central (United Kingdom)

AMPA receptors (AMPARs) are critical for synaptic plasticity, and are subject to alterations based on subunit composition and receptor trafficking to and from the plasma membrane. One of the...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Reactor pressure vessel (RPV) steels are subjected to neutron irradiation at a temperature of about 290 deg C. This radiation exposure alters the mechanical properties, leading to a shift of the brittle-to-ductile transition temperature toward higher temperatures and to a diminution of the rupture energy as determined by Charpy V-notch tests. This radiation embrittlement is one of the important aging factors of nuclear power plants. U.S. NRC recommended the basic requirements for the determination of the pressure vessel fluence by regulatory guide DG-1025 in order to reduce the uncertainty in the determination of neutron fluence calculation and measurements. The determination of the pressure vessel fluence is based on both calculations and measurements. The fluence prediction is made with a calculation and the measurements are used to qualify the calculational methodology. Because of the importance and the difficulty of these calculations, the ...

Energy Technology Data Exchange (ETDEWEB)

Expression of IGF-2 and changes in its expression in response to systemic endocrine alterations have not been demonstrated for adipocytes. Adipocytes were induced to develop within cultures of 3T3-L1 cells using a medium containing 0.5mM isobutylmethylxanthine, 1uM insulin and 100ng hydrocortisone/ml for 48 hours of exposure. Cultures containing developing adipocytes were incubated with 10% pig serum and 1 uM insulin for several days. The resultant adipocyte cultures were then treated with either 10% pig serum, diabetic pig serum or hypophysectomized pig serum in DMEM for 48 hours. Adipocytes within the cultures were separated from undifferentiated cells using percoll density gradient centrifugation. Total RNA was isolated from adipocytes and dot blotted. Blots were probed with a {sup 32}P-cDNA probe for rat IGF-2. IGF-2 was expressed by the adipocytes and the pattern of expression showed specific differences between serum treatments; IGF-2 expression was highest ...

Science.gov (United States)

The insulin signaling pathway, involving protein kinase B (PKB) and mitogen-activated protein kinase (MAPK), mediates the biological response to insulin and several growth factors and cytokines. To investigate the correlation between glucose transporter (Glut) biosynthesis and the insulin signaling pathway activated by novel compounds of Liriope platyphylla (LP9M80-H), alterations in Glut and key protein expression in the insulin signaling pathway were analyzed in the liver and brain of ICR mice treated with LP9M80-H. An in vitro assay showed that the highest level of insulin concentration was observed in the LP9M80-H-treated group, followed by the LP-H, LP-M, LP-E, and LP9M80-C-treated groups. Therefore, LP9M80-H was selected for use in studying the detailed mechanism of the insulin signaling pathway in animal systems. In an in vivo experiment, LP9M80-H induced a significant increase in glucose levels and a decrease of insulin concentration in ...

International Nuclear Information System (INIS)

A single amino acid substitution (Asp #-># Asn) at position 138 of E. coli EF-Tu was induced in the tufA gene by an M13 phage oligonucleotide site-directed mutagenesis protocol. The mutated tufA gene was then subcloned in a plasmid vector and expressed in maxicells. The properties of ["3"5S]methionine labelled mutant and wild type EF-Tu's were compared by in vitro assays. Mutant and wild-type EF-Tu's bound EF-Ts with approximately equal affinities. The 138-Asn mutation greatly reduced the protein's affinity for GDP; however, this mutation dramatically increased the proteins affinity for XDP. The mutant protein forms a stable complex with phe-tRNA and XTP, which binds to ribosomes; whereas, it does not form a complex with phe-tRNA and GTP. These results suggest that in EF-Tu x NDP complexes amino acid residue 138 must interact with the substituent on C-2 of the purine ring. Thus in wild-type EF-Tu Asp-138 would H-bond to 2-NH_2 of GDP, and in the mutant EF-Tu ASN-138 would form an ...

Science.gov (United States)

The C isotopic composition of CH4 emissions are strongly influenced by the pathway of CH4 formation. Contrary to data from other freshwater systems, soil gas and surface flux measurements made in the tropical rain forests of Puerto Rico strongly suggest that CH4 produced in these environments was derived from CO2 reduction, rather than from acetate consumption. This study explored the effects of bacterial competition for acetate, pH, and soil structure on the pathways of CH4 formation in tropical rain forest soils. Our goal was to test two principal hypotheses: (1) ferric iron-reducing bacteria out-competed methanogens for acetate, resulting in greater CO2 reduction rather than aceticlastic methanogenesis, and (2) the low pH of tropical rain forest soils favors CO2 reduction rather than aceticlastic methanogenesis. In addition, this study also investigated the effect of destroying soil aggregate structure on the pathways and rates of CH4 production. Ferric iron-reducing bacteria ...

CERN Document Server

We study the temporal evolution of coronal loops using data from the Solar X-ray Imager (SXI) on board of GOES-12. This instrument allows us to follow in detail the full lifetime of coronal loops. The observed light curves suggest three somewhat distinct evolutionary phases: rise, main, and decay. The durations and characteristic timescales of these phases are much longer than a cooling time and indicate that the loop-averaged heating rate increases slowly, reaches a maintenance level, and then decreases slowly. This suggests that a single heating mechanism operates for the entire lifetime of the loop. For monolithic loops, the loop-averaged heating rate is the intrinsic energy release rate of the heating mechanism. For loops that are bundles of impulsively heated strands, it is an indication of the frequency of occurrence of individual heating events, or nanoflares. We show that the timescale of the loop-averaged heating rate is proportional to the timescale of ...

British Library Electronic Table of Contents (United Kingdom)

Phenomenological sociology was founded at the beginning of 1930s by Alfred Schutz. His mundane phenomenology sought to combine impulses drawn from Husserl's transcendental phenomenology and Weber's action theory. It was made famous at the turn of 1960s and 1970s by Garfinkel's ethnomethodology and Berger & Luckmann's social constructionism. This paper deals with the notable accomplishments of Schutz and his followers and then proceeds to a shared shortcoming, which is that the phenomenological approach is unable to understand meaning in any other way but as actors's knowledge. Therefore, phenomenological sociologists are forced to describe the actor's interpretations of meaning as transparent to the actor him/herself, even if they sometimes make heroic attempts to escape the limitations of...

Energy Technology Data Exchange (ETDEWEB)

The authors present the results of their investigation of the effect of phosphorus compounds on the activity of tungsten-containing catalysts in the oxidation of ethane. They investigated tungsten-phosphorus catalysts with different phosphorus concentrations (calculated on the basis of P/sub 2/O/sub 5/). The catalysts were prepared by heat decomposition of the starting compounds at 750/sup 0/C for 4 h. As their starting compounds, they used two types of materials: heteropoly acids mixtures of monosubstituted ammonium phosphoric and tungstic acids. The specific surface area of the catalysts was determined using the nitrogen desorption method. The x-ray phase analysis was carried out using a DRON-1.5 diffractometer. The catalytic activity was determined using the impulse method in a reactor with a vibrofluidized catalyst layer.

CERN Document Server

Two relativistic approaches are considered to evaluate the quasielastic double-differential and integrated neutrino-nucleus cross sections. One, based on the relativistic impulse approximation, relies on the microscopic description of nuclear dynamics using relativistic mean field theory, and incorporates a description of the final-state interactions. The second is based on the superscaling behavior exhibited by electron scattering data and its applicability, due to the universal character of the scaling function, to the analysis of neutrino scattering reactions. The role played by the vector meson-exchange currents in the two-particle two-hole sector is also incorporated and the results obtained are compared with the recent data for neutrinos measured by the MiniBooNE Collaboration.

Science.gov (United States)

The transport of magnetospheric particles in the outer cusp region is examined by means of three-dimensional single particle codes. It is shown that, at high altitudes, particles can experience nonadiabatic motions leading to significant magnetic moment changes. It is demonstrated that this nonadiabatic behavior can be interpreted, at least partly, by the action of an impulsive centrifugal force perturbing the particle gyromotion. Systematic trajectory calculations reveal that plasma sheet ions which ExB convert toward the magnetopause from low L-shells in the dayside sector are subjected to such nonadiabatic motions. As a result of magnetic moment damping, a number of them are injected into the loss cone and subsequently precipitate near the cusp equatorward edge.

British Library Electronic Table of Contents (United Kingdom)

Based on the quarterly data from four open economies (the US, the UK, Canada, and Italy) and estimated correlations and impulse responses within the traditional vector autoregressive (VAR) analysis, we find that inflation, both in the short and long term, negatively affects consumption and investment, and has a positive influence on the current account. We propose an infinite-horizon optimizing model of an open economy with a fixed rate of time preference that explains these empirics. In this type of economy, households consume both durable and non-durable goods, firms operate under costly investment, and all the transactions involving consumption and investment are subject to cash-in-advance (CIA) constraints. Employing the new ?sign restriction? identification procedure due to Uhlig (J M...

Energy Technology Data Exchange (ETDEWEB)

Mechanical ventilation in private homes was for many years a stepchild of air conditioning engineers. A decisive impulse for change came in January 1995 with the enactment of the new Thermal Insulation Ordinance which for the first time allows house owners to exceed the usual admissible annual heating requirement by a certain amount on the condition that they equip the house with mechanical ventilation systems. (orig.) [Deutsch] Ueber lange Jahre war die mechanische Wohnungslueftung ein Stiefkind der Raumlufttechnik. Einen entscheidenden Impuls gab erst die seit Januar 1995 gueltige Waermeschutzverordnung, die erstmals zulaesst, dass ein gewisses Quantum des Jahres-Heizwaermebedarfs durch den Einbau mechanischer Wohnungslueftungen kompensiert werden kann. (orig.)

International Nuclear Information System (INIS)

In this paper experimental observations and a theoretical analysis of periodic radiation bursts and macropulse formation in the start-up phase of a free-electron laser (FEL) oscillator are presented. This microwave FEL uses a long pulse electron beam with a slowly decaying voltage. The output radiation consists of a superposition of bell-shaped macropulses, each of which is composed of a periodic sequence of short micropulses. The micropulses are separated by a cavity round-trip time. Each bell-shaped macropulse has a random start-up time and amplitude. The startup of the radiation macropulses is correlated with random current spikes on the continuous electron beam. The observed macropulse signal agrees with a theoretical calculation of the impulse response of the FEL oscillator when the shift in the FEL resonance frequency arising from the slow voltage drop of the electron beam is included in the analysis. Possible applications of the macropulse formation ...

Science.gov (United States)

A six-axis active vibration isolation system (AVIS) is designed by using the direct driven guide and ball contact mechanisms in order to have no cross-coupling between actuators. The point contact configuration gives an advantage of having an easy assembly of eight voice coil actuators to an upper and a base plate. A voice coil actuator is used since it can provide a large displacement and sufficient bandwidth required for vibration control. The AVIS is controlled considering the effect of flexible vibration mode in the upper plate and velocity sensor dynamics. A loop shaping technique and phase margin condition are applied to design a vibration controller. The performances of the AVIS are investigated in the frequency domain and finally validated by comparing with the passive isolation system. The scanning profiles of the specimen are compared together by using the atomic force microscope. The robustness of the AVIS is verified by showing the impulse response. ...

British Library Electronic Table of Contents (United Kingdom)

Experimental results of quasi-static and dynamic fracture of particle-filled polymer composite (PFPCM) "ALTUGLAS EI CH25" with a matrix of polymethylmethacrylate (PMMA) are reported in this paper. PMMA matrix is filled with rubber particles, as result a shock-resistant transparent composite is produced. The main task was to investigate experimentally and theoretically the fracture toughness of this composite under static and dynamic loading. A high-rate loading has been created by impulse magnetic field. Analysis of fracture process and its relation with the load parameters and material microstructure have been established. Application of the original testing method enabled determination of fracture toughness at very short loading times and comparison of the results with material dynamic p...

UK PubMed Central (United Kingdom)

The impact of a single seizure on cognition remains controversial. We hypothesized that a single early life seizure (sELS) on rat post-natal day (P) 7 would alter only hippocampal-dependent...Full Text Available

Science.gov (United States)

Pentaerythritol tetranitrate (PETN) is a relatively sensitive explosive used in many electroexplosive devices as well as in medicine. Of primary interest to LLNL is its use in items such as exploding bridgewire (EBW) detonators and exploding bridge foil initiators (EFI). In these devices the crystalline powder is pressed into a granular, low-density compact that can be initiated by an exploding wire or foil. The long-term stability of this pressed compact is of interest to weapon stockpile lifetime prediction studies. Key points about potential aging mechanisms can be summarized as follows: (1) There are a number of factors that can contribute to PETN instability. These include particle size, polymorphic phase transitions, crystal structure, impurities, moisture, occlusions, chemical incompatibility and biological (microorganism) action. of these factors the most important for long-term aging of high surface area powders used in detonators ...

International Nuclear Information System (INIS)

... dose rates inhalation iodine 134 krypton 88 nuclear decay quality factor

Energy Technology Data Exchange (ETDEWEB)

This paper describes the calculation method of 3-D underground structures in TDME method which measures only field components. Recently, FDTD method was developed as calculation method in time domain difference calculus, and the forward analysis accuracy of 3-D fields was rapidly improved. The survey results using a large-scale loop (600m{times}360m) were numerically analyzed by FDTD method. 16 measuring lines were prepared in both X and Y directions, and measuring points were prepared on intersection points of the measuring lines. Since signal current is staircase one, step and impulse responses of the ground were determined by calculating magnetic field and its time differentiation. The rectangular body (120m{times}120m{times}100m) of 0.2S/m in conductivity (5 ohm m in resistivity) was installed 160m under the ground as 3-D resistivity anomaly. The ground of 0.01S/m (100 ohm m) was assumed. Time variation in horizontal magnetic field vector plot of ...

Energy Technology Data Exchange (ETDEWEB)

The deliberation by the Nuclear Safety Commission was initiated on the alteration in reactor installation, as was required by the Ministry of International Trade and Industry. The alteration is the additional installation of the reactor No. 2 in the Sendai Nuclear Power Station, Kyushu Electric Power Co., Inc. It is a PWR power plant with thermal output of about 2,660 MW (electric output of 890 MW), to be installed, adjoining to the reactor No. 1 of the same type and capacity under construction. In the examination by MITI, it was confirmed that the technological capabilities for its construction and operation and the radiation protection measures in power generation are both sufficient. The contents of the examination include the siting conditions, the location and construction of reactor facilities, etc.

Energy Technology Data Exchange (ETDEWEB)

The objective of this project is to increase oil recovery from fractured reservoirs through improved fundamental understanding of the process of spontaneous imbibition by which oil is displaced from the rock matrix into the fractures. Spontaneous imbibition is fundamentally dependent on the reservoir surface free energy but this has never been investigated for rocks. In this project, the surface free energy of rocks will be determined by using liquids that can be solidified within the rock pore space at selected saturations. Thin sections of the rock then provide a two-dimensional view of the rock minerals and the occupant phases. Saturations and oil/rock, water/rock, and oil/water surface areas will be determined by advanced petrographic analysis and the surface free energy which drives spontaneous imbibition will be determined as a function of increase in wetting phase saturation. The inherent loss in surface free energy resulting from capillary instabilities at the microscopic (pore ...

UK PubMed Central (United Kingdom)

A summary of the effects presented here is given in the table. The designation "factor present" implies that there is knowledge (from human or animal studies, or both) of a specific factor(s) present...Full Text Available

UK PubMed Central (United Kingdom)

We have established a reliable method to induce invasive and non-invasive carcinomas in the heterotopically transplanted urinary bladder of rats by repeated injection of N-methyl-N-nitrosourea (MNU),...Full Text Available

UK PubMed Central (United Kingdom)

In addition to the well documented role of cytokines in mediating tissue-level interactions, it is now clear that matrix macromolecules fulfil a complementary regulatory function. Data highlighted in...Full Text Available

UK PubMed Central (United Kingdom)

The rolB gene of Agrobacterium rhizogenes, whose expression stimulates the formation of roots by transformed plant tissues and other growth alterations in transgenic plants, codes for a beta-glucosidase...Full Text Available

UK PubMed Central (United Kingdom)

Altered structure, and hence function, of cellular macromolecules caused by oxidation can contribute to loss of physiological function with age. Here, we tested whether the lifespan of bats, which generally...Full Text Available

UK PubMed Central (United Kingdom)

Alterations in mass transport patterns of low-density lipoproteins (LDL) and oxygen are known to cause atherosclerosis in larger arteries. We hypothesise that the species transport processes in coronary...Full Text Available

UK PubMed Central (United Kingdom)

SummaryThe life span of C. elegans can be increased via reduced function of the mitochondria; however, the extent to which mitochondrial alteration in a single,...Full Text Available

UK PubMed Central (United Kingdom)

A facile synthetic protocol for the production of neomycin B derivatives with various modifications at the 5″ position has been developed. Structural activity relationship (SAR) against...Full Text Available

UK PubMed Central (United Kingdom)

Interleukin 12 (IL-12) activates natural killer (NK) and T cells with the secondary synthesis and release of interferon-gamma (IFN-gamma) and other cytokines. IL-12-induced organ alterations are reported...Full Text Available

UK PubMed Central (United Kingdom)

Some pathological conditions with feeding pattern alterations, including obesity and Huntington disease (HD) are associated with hypothalamic dysfunction and neuronal cell death. Additionally, the hypothalamus...Full Text Available

UK PubMed Central (United Kingdom)

Because many diseases of the Western Hemisphere are hormone-dependent cancers, we have postulated that the Western diet, compared to a vegetarian or semivegetarian diet, may alter hormone production,...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundRetinitis pigmentosa (RP) is characterized by progressive night blindness, visual field loss, altered vascular permeability and loss of central vision. Currently there...Full Text Available

UK PubMed Central (United Kingdom)

OBJECTIVE—Identification of arterial genes and pathways altered in obesity and diabetes.RESEARCH DESIGN AND METHODS—Aortic gene expression profiles of...Full Text Available

UK PubMed Central (United Kingdom)

The HTLV-1 Tax protein both activates viral replication and is involved in HTLV-1-mediated transformation of T lymphocytes. The transforming properties of Tax include altering the expression of select...Full Text Available

UK PubMed Central (United Kingdom)

A number of studies have examined the functional roles of individual muscles during normal walking, but few studies have examined which are the primary muscles that respond to changes in external...Full Text Available

UK PubMed Central (United Kingdom)

Maternal prenatal undernutrition predisposes offspring to higher adiposity in adulthood. Mechanisms involved in these programming effects, apart from those described in central nervous system development,...Full Text Available

UK PubMed Central (United Kingdom)

We showed recently that secretion of glutamate in biotin-limited cells of Corynebacterium glutamicum is mediated by carrier systems in the plasma membrane (C. Hoischen and R. Krämer, Arch. Microbiol....Full Text Available

UK PubMed Central (United Kingdom)

While genomic alterations identified in human tumors using techniques such as comparative genomic hybridisation (CGH) may be recurrent, they frequently encompass large regions, in some cases...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundRecent data show aberrant and altered expression of regulatory noncoding micro (mi) RNAs in prostate cancer (PCa). A large number of miRNAs are encoded in organized intronic...Full Text Available

UK PubMed Central (United Kingdom)

Insect growth regulators (IGRs) of the juvenile hormone type alter physiological processes essential to insect development and appear to act specifically on insects. Three natural juvenile hormones...Full Text Available

UK PubMed Central (United Kingdom)

Damage to the anterior talofibular ligament (ATFL) and cacaneofibular ligament (CFL) during ankle sprain may be linked to the development of osteoarthritis. Altered tibiotalar kinematics have...Full Text Available

UK PubMed Central (United Kingdom)

PurposePrevious studies suggest that some common medications alter prostate-specific antigen (PSA) levels. It remains unclear whether these reported medication effects are due to...Full Text Available

UK PubMed Central (United Kingdom)

Neonatal administration of the synthetic glucocorticoid, dexamethasone (DEX) retards brain growth, alters adult behaviors and induces cell death in the rat brain, thereby implicating glucocorticoids...Full Text Available

UK PubMed Central (United Kingdom)

Aims: To ascertain why 19.6% of pregnancies in which a fetal renal anomaly has been detected fail to produce a surviving child, and whether antenatal diagnostic accuracy has altered since...Full Text Available

UK PubMed Central (United Kingdom)

Silent information regulators are potent NAD⁺-dependent protein deacetylases, which have been shown to regulate gene silencing, muscle differentiation and DNA damage repair. Here,...Full Text Available

UK PubMed Central (United Kingdom)

An assessment has been made of biochemical alterations in renal and hepatic functions of 73 male operators employed for an average of 8.2 years (range 0.5-23 years) in a chemical plant producing chlorinated...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundTrichloroethylene (TCE) may induce oxidative stress which generates free radicals and alters antioxidants or oxygen-free radical scavenging enzymes.MethodsTwenty...Full Text Available

Science.gov (United States)

... Gastrointestinal Tract On the Growth and Development of Hymenolepis DiminutaKerry L. Dwinell, Paul Bass, Gordon L. Telford, ... central (CNS) nervous systems in the development of Hymenolepis diminuta usi...

UK PubMed Central (United Kingdom)

ObjectiveThe present study was undertaken to analyze the impact of epigenetic alterations with a main focus on nuclear area, aneuploidy, hyperploidy, and proliferation...Full Text Available

UK PubMed Central (United Kingdom)

Normal healthy volunteers underwent broncho-alveolar lavage and the cells obtained were cultured for 24 h and 48 h, either alone or in the presence of the corticosteroid, Budesonide. Cell differentials...Full Text Available

UK PubMed Central (United Kingdom)

The zebrafish is emerging as a prominent model system for studying the genetics of human development and disease. Genetic alterations that underlie each mutant model can exist in the form of...Full Text Available

UK PubMed Central (United Kingdom)

MicroRNAs (miRNAs) have been implicated to play key roles in normal physiological functions, and altered expression of specific miRNAs has been associated with a number of diseases. It is of great interest...Full Text Available

Science.gov (United States)

Nov 18, 2010 ... Roughly speaking, the fidelity interval we quote is a "3 sigma" value. ... surface of the foremost quartz filter which is then chemically altered by ... ( CERES) scanner point accuracy using a coastline detection system", ...

UK PubMed Central (United Kingdom)

BackgroundPostnatal glucocorticoid therapy in premature infants diminishes chronic lung disease, but it also increases the risk of hypertension in adulthood. Since glucocorticoid...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundCystic ovarian disease is an important cause of infertility that affects bovine, ovine, caprine and porcine species and even human beings. Alterations in the ovarian micro-environment...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe production of high yields of recombinant proteins is an enduring bottleneck in the post-genomic sciences that has yet to be addressed in a truly rational manner. Typically...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundIn vitro data suggest that changes in myocardial substrate metabolism may contribute to impaired myocardial function in diabetic cardiomyopathy (DCM)....Full Text Available

UK PubMed Central (United Kingdom)

BackgroundMale infertility is a common cause of reproductive failure in humans. In mice, targeted deletions of the genes coding for FKBP6 or FKBP52, members of the FK506 binding...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The Nuclear Safety Commission presented the report to the Minister of International Trade and Industry on April 5, 1984, after the careful investigation and deliberation on the alteration of installation of No.1 and No.2 reactor facilities in the Sendai Nuclear Power Station. The technical capability of Kyushu Electric Power Co., Inc., was recognized to be adequate. It was judged that the safety after this alteration of installation of the reactor facilities can be ensured. The main items of examination were as follows. The mechanical, nuclear and thermo-hydraulic designs of 17 x 17 B-type fuel assemblies were regarded as adequate. The coexistence of A-type and B-type fuel assemblies does not cause any problem about the safety. The safety at the time of abnormal transient change and accident in the mixed fuel assembly core was confirmed. In No.2 reactor, the degree of enrichment of the fuel for replacement and the number of fuel assemblies to ...

UK PubMed Central (United Kingdom)

The question of whether storage of red blood cells (RBCs) alters their capacity to deliver oxygen and affects patient outcomes remains in a state of clinical equipoise. Studies of the changes...Full Text Available

UK PubMed Central (United Kingdom)

Mechanical forces can regulate various functions in living cells. The cytoskeleton is a crucial element for the transduction of forces in cell-internal signals and subsequent biological responses. Accordingly,...Full Text Available

UK PubMed Central (United Kingdom)

Experiments were conducted to investigate indole-3-acetic acid (IAA) and abscisic acid (ABA) metabolism associated with postanthesis senescence of ovaries from nonpollinated muskmelon (Cucumis...Full Text Available

UK PubMed Central (United Kingdom)

Normal urinary bladder function requires contraction and relaxation of the detrusor smooth muscle (DSM). The DSM undergoes compensatory hypertrophy in response to partial bladder outlet obstruction...Full Text Available

UK PubMed Central (United Kingdom)

PurposeHyperglycemia and hypertension contribute to the development of diabetic retinopathy, and this may involve alterations in the normal retinal cell cycle. In this work, we examined...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Accelerated aging tests have been conducted to evaluate the long-term durability of cementitious material against aggressive ions. In tests, cementitious specimens were immersed in the solutions containing concentrated aggressive ions at high temperature and it promoted diffusion of the ions in the specimen. This method would be suitable for the evaluation on the aging as the alteration of the specimen would be expected to resemble the natural behavior. This paper presents a classification of alteration mechanism in the immersion tests using MgCl{sub 2} and Na{sub 2}SO{sub 4} solution. This classification was done by relating the changes of compressive strength to microscopic and mineralogical changes.

UK PubMed Central (United Kingdom)

Dysregulation of the alternative pathway of complement activation, caused by mutations or polymorphisms in the genes encoding factor H, membrane co-factor protein, factor I or factor B, is associated...Full Text Available

UK PubMed Central (United Kingdom)

Human Factor VIII/von Willebrand factor, purified by calcium citrate-cellulose chromatography and 4% agarose gel filtration was subjected to sodium dodecyl sulfate gel electrophoresis on gels containing...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Visual excitation is initiated by the absorption of a photon by the 11-cis retinal chromophore bound within the pigment called rhodopsin. We have used a variety of vibrational spectroscopies to obtain information about the vibrational nuclear dynamics that lead to this efficient photochemical isomerization. The cis-trans isomerization in rhodopsin is complete in only 200 fs. The extreme speed of this process, which is consistent with the {approximately}50 fs lifetime indicated by the spontaneous emission yield, suggests that the photochemistry involves non-stationary states or vibrational coherence. Recent studies have in fact observed vibrationally coherent oscillations of the ground state photoproduct called bathorhodopsin following impulsive excitation of the rhodopsin reactant. This conclusively demonstrates that the isomerization process in rhodopsin is vibrationally coherent. These observations further suggest that the isomerization quantum yield is directly ...

International Nuclear Information System (INIS)

The /sup 40/Ca(p,n)/sup 40/Sc reaction was studied at 134 MeV. Neutron energy spectra were measured by the time-of-flight technique with resolutions of 220 keV at angles from 0"0 to 41"0 and 415 keV out to 62"0. The 2"-,3"-,4"-,5"- band of states based on the (f/sub 7/2/,d/sub 3/2//sup -1/) 1p1h structure was observed at low excitation energies, in good agreement with known analog states in /sup 40/Ca and /sup 40/K. The shapes of the cross-section and analyzing-power angular distributions are in good agreement with distorted-wave impulse-approximation calculations using simple 1p1h (Tamm-Dancoff approximation) shell-model wave functions. A relatively strong transition to a state at E/sub x/ = 2.3 MeV with L = 3 is identified tentatively as a 4"- state with the predominant 1p1h structure (1f/sub 7/2/,2s/sub 1/2//sup -1/).

Energy Technology Data Exchange (ETDEWEB)

An IEC-TDG waveform analysis program that can accurately calculate the waveform parameters in waveforms containing much noise as well as waveforms based on the IEC 1083-2 standard was developed in the impulse voltage and current test field. In the conventional curve fitting method, it is difficult to solve the non-linear equation directly when obtaining waveform parameters from the assigned discrete data. An approximate solution method is low in precision. Therefore, the residual between the standardized data and approximate function was calculated for high-speed Fourier transformation. Unrelated components were eliminated from the calculated frequency spectrum to synthesize waveforms. An L-M method is used for analysis. The solution is first tracked by a maximum diving method. If the convergence is judged to have been largely promoted, the method is switched into a Newton method to continue the calculation. The non-linear equation in a curve fitting part can be ...

Energy Technology Data Exchange (ETDEWEB)

Finite-difference acoustic-wave modeling and reverse-time depth migration based on the full wave equation are general approaches that can take into account arbitrary variations in velocity and density and can handle turning waves as well. However, conventional finite-difference methods for solving the acoustic- or elastic-wave equation suffer from numerical dispersion when too few samples per wavelength are used. The flux-corrected transport (FCT) algorithm, adapted from hydrodynamics, reduces the numerical dispersion in finite-difference wavefield continuation. The flux-correction procedure endeavors to incorporate diffusion into the wavefield continuation process only where needed to suppress the numerical dispersion. Incorporating the flux-correction procedure in conventional finite-difference modeling or reverse-time migration can provide finite-difference solutions with no numerical dispersion even for impulsive sources. The FCT correction, which can be ...

Energy Technology Data Exchange (ETDEWEB)

Inelastic scattering of 180 MeV {pi}{sup +} and {pi}{sup {minus}} from {sup 52}Cr shows an angular distribution for the 2{sub 2}{sup +} state at 2.96 MeV that differs greatly from the usual {ital L} = 2 shapes for 2{sup +} states. This state is perhaps the only case from pion-inelastic scattering in which standard distorted-wave impulse approximation models (including multistep and single-step responses) fail to reproduce the measured angular distribution. Furthermore, this unique excitation has been shown to have the features expected of a seniority-four proton excitation yet the pion data show charge symmetry. While coupled-channel calculations are not able to reproduce the pion data, they do agree with the shape observed for 42 MeV {alpha} particle scattering to this state, but the magnitude of the {alpha} scattering data is not consistent with a collective model and known {gamma} ray deexcitations. Scattering to the first and third 2{sup +} states of {sup 52}Cr ...

Science.gov (United States)

A first-principles task-based approach to the design of medical ultrasonic imaging systems for breast lesion discrimination is described. This study explores a new approximation to the ideal Bayesian observer strategy that allows for object heterogeneity. The new method, called iterative Wiener filtering, is implemented using echo data simulations and a phantom study. We studied five lesion features closely associated with visual discrimination for clinical diagnosis. A series of human observer measurements for the same image data allowed us to quantitatively compare alternative beamforming strategies through measurements of visual discrimination efficiency. Employing the Smith-Wagner model observer, we were able to breakdown efficiency estimates and identify the processing stage at which performance losses occur. The methods were implemented using a commercial scanner and a cyst phantom to explore development of spatial filters for systems with shift-variant ...

Energy Technology Data Exchange (ETDEWEB)

A system for real-time neutron radiography of moving objects is described. It comprise a source adapted to generate a continuous uninterrupted series of neutron pulses. Each pulse has a predetermined peak power and duration compatible with the framing times of a real-time video imaging system. A transporter moves an object to be examined to bring sequentially position selected portions of the object in the path of the pulses. Where the object itself has moving components, pulses are sequentially incident on the object. According to any dissimilarities, the object will alter the intensity of the neutrons passing therethrough. In order to record separately the changes in the neutron intensity, for each pulse, an imager is positioned to receive the neutron beam pulses which have been altered by their passage through the object and produce images indicating intensity alterations. A refrigerated beryllium filter can be used to ...

Science.gov (United States)

Anxiety is a common symptom during ethanol withdrawal contributing to its continuous abuse and alcoholism. Ethanol withdrawal in rats produces an interoceptive discriminative stimulus (IDS) similar to that produced by the anxiogenic drug pentylenetetrazol (PTZ). This stimulus peaks at 12 hours after last dose of ethanol and thereafter the IDS is detected for several days (protracted withdrawal) by sensitization to a probe drug. previously, the authors have shown that during the protracted withdrawal, the IDS is enhanced by GABA receptor antagonists suggesting alteration of brain GABA systems. This report provides further evidence that chronic ethanol alters GABAergic systems. Rats were trained to discriminate PTZ (20 mg/kg, ip) from saline. Diazepam, pentobarbital and phenobarbital blocked the PTZ-IDS dose dependently. Ethanol, 4.5% w/v, was then given in a nutritionally complete diet for a week. On termination of the ethanol diet, rats ...

International Nuclear Information System (INIS)

We discuss the consequence of local duality for elastic scattering, and derive a model-independent equation between structure functions at x ? 1 and elastic electromagnetic form factors. Then the electromagnetic form factors of proton are discussed using the quark-hadron duality theory. We also debate the form factor of proton in a bound state. It may be an effective approach to study the form factor of proton in media.

International Nuclear Information System (INIS)

It is a useful hypothesis to thing of the reaction to protein deprivation as made up of two parts. First there is an initial adaptation involving rapid losses of protein. This is followed by slow continuing depletion. When considering two organ groups, such as the liver and muscle, it appears that the curve of urinary nitrogen excretion reflects the different parts they play in these two phases. The changes in the relative amounts of protein in different organs results in an alteration in the pattern of body protein at the level of the organ, the tissue and the cell. These changes are themselves the result of altered rates of synthesis and breakdown. The questions that must be asked and hopefully will be answered with the help of isotopes, are how these changes are brought about, how they are inter-related and controlled, and what is their significance? This paper contains a discussion of the few results that have been obtained so far. 1 fig.

British Library Electronic Table of Contents (United Kingdom)

The present study was designed with an aim to analyze the effect of acute aluminium phosphide (ALP) exposure (10mg/kg b.wt, intragastrically) on the kinetic characteristics of cytochrome oxidase and energy metabolism in male Wistar rat liver mitochondria. Liver mitochondrial preparations from ALP-treated rats exhibited significant decrease (66%) in the activity of cytochrome oxidase suggesting that there was a decrease in the catalytic efficiency of the active oxidase molecules on ALP treatment. The decreased activity of cytochrome oxidase with altered NADH and succinic dehydrogenase activities might have contributed towards a significant decline in state 3 and state 4 respiration as observed. These alterations in the electron transport chain complexes in turn adversely affected the ATP sy...

British Library Electronic Table of Contents (United Kingdom)

BACKGROUND Hypermethylation of CpG islands is a common epigenetic alteration associated with cancer. Tumor suppressor genes retinoic acid receptor beta (RARb) and PDLIM4 are hypermethylated and silenced in prostate cancer (PCa) tissues and PCa cell lines compared to normal prostate cells. METHODS In this study, a benign prostate epithelial cell line RWPE1 was used as a model to study the epigenetic regulation of Myc on the RARb and PDLIM4 promoters. Forced Myc overexpression inhibited the RARb and PDLIM4 expression. RESULTS Pyrosequencing study showed that Myc overexpression increased methylation in several CpG sites of both promoters. A DNA methylation inhibitor 5-aza-2prime-deoxycytidine reversed the epigenetic alteration effect of Myc on both RARb and PDLIM4. CONCLUSION The epigenetic r...

British Library Electronic Table of Contents (United Kingdom)

Measurement of serum biochemical parameters in response to metal exposures can be especially useful to help identify target organs of toxicity as well as the general health status of animals. Oreochromis niloticus were exposed to 5.0?mg/L?Zn, 1.0?mg/L?Cd, and 5.0?mg/L?Zn?+?1.0?mg/L?Cd mixture for 7 and 28?days, and alterations in serum enzyme activities and ion levels were measured. Significant changes in all the biochemical parameters were found to be time dependent. Following metal exposure, alkaline phosphatase activity was elevated at both exposure periods. No changes in activities of lactate dehydrogenase and lipase were observed in response to single or combined Zn and Cd exposure at 7?days while they increased at 28?days. Fish exposed to metals showed a decrease in cholinesterase ac...

UK PubMed Central (United Kingdom)

Background:Tobacco smoking is the most important risk factor for chronic obstructive pulmonary disease (COPD) development. Inhaled cigarette smoke can induce tumor necrosis factor-α...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The experiments at the incinerator for low-level wastes processing, (containing transuranium radionuclides) are described. Air decontamination factors and detector readings correction factors for efficiency and absorption are indicated.

UK PubMed Central (United Kingdom)

A fluid-phase immunoradiometric assay has been developed which identifies an antigen on the Factor VIII (antihemophilic factor) procoagulant protein. This sensitive and quantitative assay is not influenced...Full Text Available

UK PubMed Central (United Kingdom)

Caries is a multifactorial disease, and studies aiming to unravel the factors modulating its etiology must consider all known predisposing factors. One major factor is bacterial colonization,...Full Text Available

UK PubMed Central (United Kingdom)

The extracellular domain of human fibroblast growth factor receptor (XC-FGF-R) was expressed in Escherichia coli. The protein was purified to homogeneity and the interaction with basic fibroblast growth...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Radium is known to be taken up by aquatic animals, and tends to accumulate in bone, shell and exoskeleton. The most common approach to estimating the uptake of a radionuclide by aquatic animals for use in health and environmental risk assessments is the concentration factor method. The concentration factor method relates the concentration of a contaminant in an organism to the concentration in the surrounding water. Site specific data are not usually available, and generic, default values are often used in risk assessment studies. This paper describes the concentration factor method, summarizes some of the variables which may influence the concentration factor for radium, reviews reported concentration factors measured in marine environments and presents concentration factors derived from data collected in a study in coastal Louisiana. The use of generic default ...

Science.gov (United States)

... implementation." 4 1 Factors Affecting Rural Construction. Two new factors profoundly modify today's pacification equa- tion. ...

Energy Technology Data Exchange (ETDEWEB)

The data base for the form factors of the nucleon obtained from elastic ep scattering is discussed, as well as some recent developments in their calculation.

Energy Technology Data Exchange (ETDEWEB)

This is a presentation on Human Factors in reactor operations. It discusses issues that deal with power plant operations, training and design, operational effectiveness and safety, supporting people to achieve effective and error free performance.

CERN Document Server

The stock market has been known to form homogeneous stock groups with a higher correlation among different stocks according to common economic factors that influence individual stocks. We investigate the role of common economic factors in the market in the formation of stock networks, using the arbitrage pricing model reflecting essential properties of common economic factors. We find that the degree of consistency between real and model stock networks increases as additional common economic factors are incorporated into our model. Furthermore, we find that individual stocks with a large number of links to other stocks in a network are more highly correlated with common economic factors than those with a small number of links. This suggests that common economic factors in the stock market can be understood in terms of deterministic factors.

Wastenet

... By applying non-market valuation methods, we focus on analysing individual preferences in respect of (environmental) non-market goods. The principal object of research interest is the valuation of pollution impacts and effects of working processes on human health resulting in premature deaths, risk alterations, and various disease symptoms. We also deal with valuation of non-production ecosystem (forest) functions and benefits, inter alia ...

International Nuclear Information System (INIS)

This work presents the spectroscopic results of the investigations of ancient pottery remains excavated in ancient Kremna (BURDUR-TURKEY). The micro-Raman and FT-IR spectroscopic studies of the pottery remains belonging to sixth century allowed us to identify the mineral composition. Some examples are described of the use of this technique in the field of art conservation and diagnostics, with regard to pigments, and some products of metal alteration.

DEFF Research Database (Denmark)

In male rodents, anogenital distance (AGD) provides a sensitive and continuous correlate of androgen exposure in the intrauterine environment and predicts later reproductive success. Some endocrine-disrupting chemicals can alter male reproductive tract development, including shortening AGD, in both rodents and humans. Whether AGD is related to semen quality in human is unknown.

Science.gov (United States)

Only a small number of radiation accidents in the United States have been severe enough to result in multi-organ failure (MOF). Medical details of selected medical misadministration and criticality cases are reviewed, with an emphasis on pathophysiology. The four criticality cases are particularly relevant for analysis of MOF, since medical treatment was supportive and did not appreciably alter the clinical evolution of radiation injury. PMID:15975871

UK PubMed Central (United Kingdom)

Low-level lead exposure during early childhood has long been associated with altered neurocognitive development and diminished cognitive functions. Over nine thousand U.S. industrial facilities...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

We study by means of Quantum Monte Carlo simulations based on the Worm Algorithm the low temperature (down to T = 0.05 K) properties of parahydrogen clusters comprising up to 40 molecules. Three different intermolecular interactions are employed: the Silvera-Goldman, the Buck and the Lennard-Jones potential. Despite important discrepancies observed in the numerical estimates of energy and superfluid fraction, the mechanism by which clusters melt at low T is independent of the particular choice of the potential, whose only effect is to alter the temperature scale.

UK PubMed Central (United Kingdom)

BackgroundThe large sensitivity, high reproducibility and essentially unlimited dynamic range of real-time PCR to measure gene expression in complex samples provides the opportunity...Full Text Available

UK PubMed Central (United Kingdom)

One of the drawbacks in improving the aroma properties of tomato (Solanum lycopersicum) fruit is the complexity of this organoleptic trait, with a great variety of volatiles contributing...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

An improved hydrocarbon fuel is described selected from the group consisting of gasoline, diesel fuel, kerosene, jet fuel, No. 1 heating oil, and No. 2 heating oil containing a detectable amount of one or more fullerene additives therein serving as identification means for said fuel wherein said fullerenes are present in an amount insufficient to alter any of the combustion properties of the fuel.

Energy Technology Data Exchange (ETDEWEB)

Within the Westeuropean network of the electric current supply a continuing compensation is necessary with respect to the permanent alterations of capacity and frequency. Pumped-storage plants are of considerable significance to meet these requests. The Schluchseewerk AG, Freiburg/Breisgau, has among others five pumped-storage plants in the southern part of the Black Forest. The conception and the operation of them are described. (orig.).

Energy Technology Data Exchange (ETDEWEB)

The radiologic appearance of inflammatory and tumorous lesions in the iliac bone is characterized by destructive alterations and consolidations simultaneously. This pattern is nonspecific. The value of plain films of this area is compromised by the anatomy of the iliac bone and by overlying structures. Therefore tomography, computer tomography and bone scans are necessary. Difficulties in differentiation between benign and malignant lesions are discussed and case reports are given. The importance of histologic examination is stressed.

UK PubMed Central (United Kingdom)

Dengue virus (DENV) infection is a worsening global health problem. The plaque reduction neutralization test (PRNT) is currently considered to be the “gold standard” to characterize...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Electron beam therapy applied to a lymph node metastasis from a squamous cell carcinoma was followed by the development of histologically and immunologically typical bullous pemphigoid, the lesions being initially strictly confined to the irradiation area. This observation suggests that the bullous pemphigoid antigen may be altered or unmasked by electron beam radiotherapy, leading subsequently to the production of autoantibodies. The disease in this case effectively responded to the administration of tetracycline and niacinamide, a therapeutic regimen described recently.

Science.gov (United States)

Scanning electron microscopy and an electron-microprobe analysis of a sample of blast furnace (BF) coke have revealed alkalization (5.64 wt % Na{sub 2}O + K{sub 2}O) and Al saturation (17.28 wt % Al{sub 2}O{sub 3}) of SiO{sub 2} by BF gases. The K/Na{sub at} value of 1.15 in the new phase (alteration zone) reflects close atomic proportions of the elements and suggests that the abilities to incorporate K and Na during the process are almost equal. This Al saturation and alkalization of SiO{sub 2} indicates an active role for Al along with alkali metals in BF gases. The average width of the altered area in the SiO{sub 2} grain is about 10 m, which suggests that SiO{sub 2} particles of that size can be transformed fully to the new phase, provided that at least one of their faces is open to an external pore (surface of the coke) or internal pore with circulating BF gases. The grains that exceed 10 {mu}m can only be partly ...

UK PubMed Central (United Kingdom)

Gonadotropin–releasing hormone (GnRH) neurons are the central regulators of reproduction. GABAergic transmission plays a critical role in pubertal activation of pulsatile GnRH secretion....Full Text Available

UK PubMed Central (United Kingdom)

In superior cervical ganglion (SCG) neurons calcium-induced calcium release (CICR), mediated by ryanodine receptors (RyRs), contributes to stimulation-evoked intracellular calcium ([Ca²⁺]_i)...Full Text Available

International Nuclear Information System (INIS)

The U.S. Department of Energy's (DOE) Savannah River Site (SRS) is decommissioning many of its excess facilities through removal of the facility structures leaving only the concrete-slab foundations in place. Site-specific, risk-based derived concentration guideline levels (DCGLs) for radionuclides have been determined for a future industrial worker potentially exposed to residual contamination on these concrete slabs as described in Jannik. These risk-based DCGLs were estimated for an exposure area of 100 m2. During deactivation and decommissioning (D and D) operations at SRS, the need for area factors for larger and smaller contaminated areas arose. This paper compares the area factors determined for an industrial worker exposed to a concrete slab end-state for several radionuclides of concern at SRS with 1) the illustrative area factors provided in MARSSIM, 2) the area correction factors provided in ...

KoreaScience (Korea)

Full Text Available

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

KoreaScience (Korea)

Full Text Available

KoreaScience (Korea)

Full Text Available

KoreaScience (Korea)

Full Text Available

KoreaScience (Korea)

Full Text Available

KoreaScience (Korea)

Full Text Available

International Science & Technology Center (ISTC)

Determination of the Ecology Factor for the Magistral Oil Pipelines, Working in Difficult Hilly and Geology Conditions

International Nuclear Information System (INIS)

Short communication.

KoreaScience (Korea)

Full Text Available

KoreaScience (Korea)

Full Text Available

International Nuclear Information System (INIS)

Collection, analysis and quantification of human factor data are important compositions of human reliability analysis (HRA) and probabilistic risk assessment (PRA). Various human factor databases have been set up, but there are comparatively little human factor data management systems which can be uses for collection, classification, analysis, calculation and predication of the human factor data. Therefore, the human factor data management system for Daya Bay NPP is developed, with the following three modules and four databases: original data module, computing module, introduced data module, and basic database, other data source of the plant, external database and introduced database. The foundational problems about human factor data and the systemic structure and function are described. The data structure in the database is also discussed, because it is of the ...

International Nuclear Information System (INIS)

Transients induced in nuclear power plants from many sources result in one or more fluid conditions changing with time. Fluid conditions of pressure, inlet temperature, inlet flow, or even system power many change separately or in conjunction with each other. The result of the condition change may be one which induces departure from nucleate boiling. An experimental investigation of transient which were intended to achieve Critical Heat Flux was performed at the Heat Transfer Research Facility of Columbia University for Siemens Nuclear Power Corporation. The transients were set up to include broad ranges of flow and pressure conditions near the operating range of pressurized water reactors. Transient events were dominated by varying single conditions and measuring the response of the system and of the rod thermocouples. Because of coupling effects within the test loop, secondary conditions would also vary. In order to perform controlled tests which achieved the desired result, CHF ...

Energy Technology Data Exchange (ETDEWEB)

Cross sections for some electro- and photoinduced spallation reactions on {sup 27}Al and {sup 51}V are measured in the energy region 130 MeV to 580 MeV with the activation method. Comparisons are made with calculations based on the Dalitz formalism for virtual photon spectra, and Monte Carlo calculations based on a cascade evaporation model, respectively. By use of Bremsstrahlung with end-point energies from threshold to 750 MeV, the yields for photo- production of{pi}{sup -}leading to ground and isomeric states in {sup 197}Hg are measured with the activation method. The activity from the Hg-isotopes were measured after a chemical separation of Hg from the target material. The yields and isomeric ratios are compared with impulse approximation calculations. For the photoproduction of {sup 195m}Hg and {sup 192}Hg from {sup 197}Au, the yields were measured. The experimental mean cross sections are compared with data from other experiments and with cascade evaporation ...

Science.gov (United States)

Elastic electromagnetic form factors of nucleons are investigated for both the time-like and the space-like momenta by using the unsubtracted dispersion relation with QCD constraints. It is shown that the calculated form factors reproduce the experimental data reasonably well; they agree with recent experimental data for the neutron magnetic form factors for the space-like data obtained by the CLAS Collaboration and are compatible with the ratio of the electric and magnetic form factors for the time-like momentum obtained by the BABAR Collaboration.

Science.gov (United States)

Systemic sclerosis is an autoimmune connective tissue disorder characterized by a widespread microangiopathy, autoimmunity and fibrosis of the skin and of various internal organs. Microangiopathy is characterized by a reduced capillary density and an irregular chaotic architecture that lead to chronic tissue hypoxia. Despite the hypoxic conditions, there is no evidence for a sufficient compensative angiogenesis in SSc. Furthermore, vasculogenesis is also impaired. An imbalance between angiogenic and angiostatic factors might explain the pathogenetic mechanisms of SSc vasculopathy. As far as angiogenic factors are concerned, within the most important are vascular endothelial growth factor (VEGF) and its receptors, platelet derived growth factor (PDGF), transforming growth factor beta (TGF-?), fibroblast growth factor -2 (FGF-2), angiopoietin 1 (Ang-1), stromal ...

CERN Document Server

The activity assay of a radiopharmaceutical administration to a patient is normally achieved via the use of a radionuclide calibrator. Because of the different geometries and elemental compositions between plastic syringes and glass vials, the calibration factors for syringes may well be significantly different from those for the glass containers. The magnitude of these differences depends on the energies of the emitted photons. For some radionuclides variations have been observed of 70 %, it is therefore important to recalibrate for syringes or use syringe calibration factors. Calibration factors and volume correction factors have been derived for the NPL secondary standard radionuclide calibrator, for a variety of commonly used syringes and needles, for the most commonly used medical radionuclide.

Science.gov (United States)

The complete world set of parity-violating electron scattering data up to Q{sup 2}{approx}0.3 GeV{sup 2} is analyzed. We extract the current experimental determination of the strange electric and magnetic form factors of the proton, as well as the weak axial form factors of the proton and neutron, at Q{sup 2}=0.1 GeV{sup 2}. Within experimental uncertainties, we find that the strange form factors are consistent with zero, as are the anapole contributions to the axial form factors. Nevertheless, the correlation between the strange and anapole contributions suggest that there is only a small probability that these form factors all vanish simultaneously.

Energy Technology Data Exchange (ETDEWEB)

Six illitized samples from drillhole OL-KR12 in Olkiluoto were analyzed by helium gas methods for their diffusion coefficient, permeability and porosity. The diffusion coefficients measured varied in the range 2.1 x 10-10 - 3.5 x 10-8 m2/s, permeabilities in the range 6 x 10-21 - 5.8 x 10-16 m2, and porosities in the range 0.2 6.2%. Variations observed in these quantities were concluded to arise from the heterogeneous structure of the sample rock. A 4 mm x 4 mm x 4 mm subsample was sawed from each of the six samples for structural analysis by x-ray microtomography. The three-dimensional structure of tomographic reconstructions, and thereby that of the samples themselves, was analyzed visually, which confirmed their heterogeneity. Samples represent altered rock whose structure and thereby transport properties vary significantly depending on the local alteration history of the rock. (orig.)

Energy Technology Data Exchange (ETDEWEB)

Sodium-dependent high-affinity choline uptake was measured in various regions of the brains of rats irradiated for 45 min with either pulsed or continuous-wave low-level microwaves (2,450 MHz; power density, 1 mW/cm2; average whole-body specific absorption rate, 0.6 W/kg). Pulsed microwave irradiation (2-microseconds pulses, 500 pulses/s) decreased choline uptake in the hippocampus and frontal cortex but had no significant effect on the hypothalamus, striatum, and inferior colliculus. Pretreatment with a narcotic antagonist (naloxone or naltrexone; 1 mg/kg i.p.) blocked the effect of pulsed microwaves on hippocampal choline uptake but did not significantly alter the effect on the frontal cortex. Irradiation with continuous-wave microwaves did not significantly affect choline uptake in the hippocampus, striatum, and hypothalamus but decreased the uptake in the frontal cortex. The effect on the frontal cortex was not altered by pretreatment with ...

Energy Technology Data Exchange (ETDEWEB)

Previous behavioral and pharmacological studies have implicated endorphins in radiation-induced locomotor hyperactivity of the C57BL/6J mouse. However, the endogenous opiate(s) responsible for this behavioral change have not been identified. The present study measured beta-endorphin-like immunoreactivity (beta-END-LI) in brain, blood, and combined brain and pituitary samples from irradiated and sham-irradiated C57BL/6J mice. After radiation exposure, levels of beta-END-LI decreased significantly in the brain. A similar, but not statistically significant, decline was measured in combined brain and pituitary samples. Concentrations of blood beta-END-LI were not changed by irradiation. These radiogenic changes in beta-END-LI are in some ways similar to those observed after other stresses. However, radiation-induced locomotor hyperactivity may be mediated more by alterations of beta-END-LI in the brain than in the periphery. Other endogenous opiate systems may also ...

Energy Technology Data Exchange (ETDEWEB)

Purpose: {sup 31}P-MRS is used to assess the influence of sex and age on quadriceps muscle metabolism before and after exercise. Materials and Methods: 32 healthy volunteers (15 women, 17 men; mean age: 38{+-}17 yrs.) were examined by dynamic phosphorus-31 ({sup 31}P) magnetic resonance spectroscopy (MRS). In the magnet, the quadriceps muscle was stressed by an isometric and an isotonic form of exercise until exhaustion, respectively. Results: Resting conditions: With increasing subjects` age, the ratio {beta}-adenosine triphosphate/total phosphate decreased (r=-0.37; p=0.02). With increasing subjects` age, the ratios inorganic phosphate/phosphocreatine (r=0.79; p=5x10{sup -8}), phosphomonoester/{beta}-adenosine triphosphate (r=0.74; p=10{sup -6}) and phosphodiester/{beta}-adenosine triphosphate (r=0.62; p=10{sup -4}) increased. The pH was the only one of the evaluated spectroscopic parameters which showed a sex-dependence: Female subjects had a significantly lower pH (7.03{+-}0.02) ...