UK PubMed Central (United Kingdom)

Several studies of facilitated communication have demonstrated that the facilitators were controlling and directing the typing, although they appeared to be unaware of doing so. Such results shift...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Our studies have shown that endotoxin intratracheally instilled into the rat lung induces proliferation of alveolar type II cells. In that study, the alveolar type II cells. In that study, the alveolar type II cell hyperplasia occurred 2 d after instillation of endotoxin and persisted for a further 2 d. After hyperplasia, the lung remodeled and returned to a normal state within 24-48 h. Understanding the mechanisms involved in the remodeling process of this transient hyperplasia may be useful to identify molecular changes that are altered in neoplasia. The purpose of the present study was to corroborate induction of epithelial cell hyperplasia by endotoxin and to delineate mechanisms involved in tissue remodeling after endotoxin-induced alveolar type II cell hyperplasia. In conclusion, immonostaining with cyclin D1 and ...

Energy Technology Data Exchange (ETDEWEB)

Irradiation with a single dose of 30 Grey on the basal regions of the lungs of Sprague-Dawley rats induced a peribronchial and alveolar inflammation. Infiltration of mast cells in the edematous alveolar interstitial tissue and also in the peribronchial tissue were characteristic features of the lesion. The appearance of mast cells was already seen 4 wk after irradiation and by weeks 6 to 8 there was a heavy infiltration. The staining properties suggested that they were connective tissue-type mast cells. The infiltration of mast cells was paralleled by an accumulation of hyaluronan (hyaluronic acid) in the alveolar interstitial tissue 6 and 8 wk after irradiation. The recovery of hyaluronan (HA) during bronchoalveolar lavage (BAL) of the lungs also increased at this time. Treatment with a mast cell secretagogue, compound 48/80, induced a distinct reduction of granulated mast cells in the ...

International Nuclear Information System (INIS)

''Paraquat lung'' which is complicated with paraquat poisoning has been a lethal pulmonary pathology presenting intra-alveolar fibrosis, but an effective therapy has not been developed so far. We hypothesized that the type II alveolar cells producing surfactant were damaged by paraquat which was actively accumulated through out the blood by alveolar epithelial cells. To prove this hypothesis, we examined the effect of an intratracheal administration of an artificial lung surfactant (surfacten, Mitsubishi Tanabe Pharma Corporation, Osaka) on mortality in a model of murine paraquat poisoning. Paraquat was given intramuscularly 3 days after the intratracheal surfactant administration. The mice used were C57BL/6J strain and Balb/C strain. The lethal dose, 50% (LD50), of paraquat was about 28 mg/kg in the C57BL/6J strain and about 9 mg/kg in the Balb/C strain, respectively. Mortalities of paraquat poisoning ...

UK PubMed Central (United Kingdom)

T-type calcium channels are responsible for generating low-threshold spikes that facilitate burst firing and neurotransmitter release in neurons. GnRH neurons exhibit burst firing, but the underlying...Full Text Available

UK PubMed Central (United Kingdom)

Two cases of pulmonary alveolar proteinosis, including one death, occurred in workers at a facility producing indium-tin oxide (ITO), a compound used in recent years to make flat panel displays. Both...Full Text Available

UK PubMed Central (United Kingdom)

Normal healthy volunteers underwent broncho-alveolar lavage and the cells obtained were cultured for 24 h and 48 h, either alone or in the presence of the corticosteroid, Budesonide. Cell differentials...Full Text Available

Wastenet

...6 Resource type: documents MmIT: Multimedia Information and Technology Group Group aiming to facilitate communication between CILIP members interested in multimedia developments in the library and information science field. Visits to places of interest like museums and archives are frequently organised, and an email discussion list ...

Energy Technology Data Exchange (ETDEWEB)

The invention deals with a pumping plant for oil filled power cables. An air driven piston type pump is used as primary pump. A PLS (Programmable Logic control System) is used to control the oil flow to the cable(s). Improvements of the pump includes means for ensuring that the pump piston is operated also at low pressure and flow, and means for sealing off the piston rod to ensure maximum life of seals, to facilitate detection of possible leakages and to avoid contamination of the cable oil. 3 figs.

British Library Electronic Table of Contents (United Kingdom)

Sinus lifting and reconstruction of localized alveolar defects are often required after closure of a large oroantral fistula (OAF) to allow for subsequent implant installation. This study describes a combined surgical technique that involves sinus lifting, bony closure, and reconstruction of the alveolar defect at the site of an OAF. The sinus membrane was reconstructed as a continuous layer by combining the residual sinus membrane with a rotated part of oral mucosa around the OAF. Autogenous bone from the chin and/or ramus was grafted into the prepared sinus space and alveolar defect, and the graft was covered by a buccal advancement flap. This technique was used to treat 8 patients who had large OAFs in the posterior maxillary region. The treatment was successful in all cases, and the te...

UK PubMed Central (United Kingdom)

Single nerve fibres innervating tooth pulp were isolated from filaments dissected from the inferior alveolar nerve in 17 anaesthetized cats. The fibres were studied to determine whether electrical stimulation...Full Text Available

UK PubMed Central (United Kingdom)

Previous experimental data from various laboratories indicate that endotoxin of gram-negative oral microorganisms might be one of the most important bacterial products involved in bone resorption during...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Regular physical activity (PA) decreases the risk of several chronic diseases including some cancers, type II diabetes, obesity, and cardiovascular disease; however, the majority of US adults are not meeting the recommended levels to experience these benefits. To address this public health concern, the underlying mechanisms for behavior change need to be understood, translated and disseminated into appropriately tailored interventions. The Transtheoretical Model (TTM) provides a framework for both the conceptualization and the measurement of behavior change, as well as facilitating promotion strategies that are individualized and easily adapted. The purpose of this manuscript is to present the constructs of the TTM as they relate to PA behavior change. We begin with a brief synopsis of rec...

Energy Technology Data Exchange (ETDEWEB)

The gene encoding the human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R1) was mapped to chromosome 7 by PCR analysis of genomic DNA from a human/rodent somatic cell hybrid mapping panel. This assignment was confirmed and the gene localized to chromosome band 7p14 by fluorescence in situ hybridization. A yeast artificial chromosome containing ADCYAP1R1 was identified in the CEPH {open_quotes}B{close_quotes} Mega-YAC library. This YAC includes two highly polymorphic dinucleotide repeat sequences that will facilitate genetic studies of the contribution of ADCYAP1R1 in disease states of the central nervous and neuroendocrine systems. 13 refs., 1 fig.

CERN Document Server

The term ``dynamo'' means different things to the laboratory fusion plasma and astrophysical plasma communities. To alleviate the resulting confusion and to facilitate interdisciplinary progress, we pinpoint conceptual differences and similarities between laboratory plasma dynamos and astrophysical dynamos. We can divide dynamos into three types: 1. magnetically dominated helical dynamos which sustain a large scale magnetic field against resistive decay and drive the magnetic geometry toward the lowest energy state, 2. flow-driven helical dynamos which amplify or sustain large scale magnetic fields in an otherwise turbulent flow, and 3. flow-driven nonhelical dynamos which amplify fields on scales at or below the driving turbulence. We discuss how all three types occur in astrophysics whereas plasma confinement device dynamos are of the first type. Type 3 dynamos requires no ...

International Nuclear Information System (INIS)

In this study, we measured the effects of different concentrations of paraquat (0,01 mM and 1,0 mM) on the 1-"1"4CO_2 and 6-"1"4CO_2 production of rabbit lung slices and isolated alveolar macrophages, in 20% and 95% oxygen phases respectively. A 95% oxygen phase induced an increase in the 6-"1"4C-glucose oxidation of control lung slices over a 3-hour period, while the increased activity of the pentose pathway over the first 2 hours started to decline during the third hour of incubation. Paraquat (1,0mM) in 20% oxygen caused a consistent increase in the 6-"1"4CO_2 production by lung slices, but in a 95% oxygen phase gradually inhibited the 6-"1"4C-glucose oxidation over a period of 3 hours. The pentose phosphate pathway was highly significantly stimulated by 1,0 mM paraquat in 20% and 95% oxygen over 3 hours. When isolated alveolar macrophages (viability 95%) were incubated in a 20% and 95% oxygen phase respectively, both the 6-"1"4C-glucose and ...

British Library Electronic Table of Contents (United Kingdom)

Background. A 19-year-old girl was diagnosed with systemic lupus erythematosus, based on findings of arthritis, malar rash, positive antinuclear antibody test and high levels of antibodies to double-stranded DNA. Two months after diagnosis, the patient presented with a sudden drop in blood hemoglobin level. Several days later, she developed bloody sputum, rapidly progressive dyspnea and hypoxemia. High-resolution CT showed diffuse alveolar infiltrates in both lung fields.Investigations. Physical examination, complete blood count, erythrocyte sedimentation rate, urinalysis, 24-h urine protein excretion, fecal occult blood test, d-dimer test, acid hemolysis test, activated partial thromboplastin time and prothrombin time, direct and indirect Coombs tests, bone marrow smear, arterial blood ga...

CERN Document Server

Two-dimensional simulations of the coarsening process of the isotropic/smectic-A phase transition are presented using a high-order Landau-de Gennes type free energy model. Defect annihilation laws for smectic disclinations, elementary dislocations, and total dislocation content are determined. The computed evolution of the orientational correlation length and disclination density is found to be in agreement with previous experimental observations showing that disclination interactions dominate the coarsening process. The mechanism of smectic disclination movement, limited by the absorption and emission of elementary dislocations, is found to be facilitated by curvature walls connecting interacting disclinations. At intermediate times in the coarsening process, split-core dislocation formation and interactions displaying an effective disclination quadrupole configuration are observed. This work provides the framework for further understanding of ...

DEFF Research Database (Denmark)

Udgivelsesdato: October 2004

Energy Technology Data Exchange (ETDEWEB)

Logistics modeling is a powerful analytical technique for effective planning of waste storage, treatment, and disposal activities. Logistics modeling facilitates analyses of alternate scenarios for future waste flows, facility schedules, and processing or handling capacities. These analyses provide an increased understanding of the specific needs for waste storage, treatment, and disposal while adequate time remains to plan accordingly. They also help to determine the sensitivity of these needs to various system parameters. This paper discusses a logistics modeling system developed by the Pacific Northwest Laboratory (PNL) to aid in solid waste planning for a large industrial complex managing many different types and classifications of waste. The basic needs for such a system are outlined, and the approach adopted in developing the system is described. A key component of this approach is the development of a conceptual model that provides a ...

Energy Technology Data Exchange (ETDEWEB)

In response to US Department of Energy directives, Argonne National Laboratory (ANL) has developed a waste minimization plan aimed at reducing the amount of wastes at this national research and development laboratory. Activities at ANL are primarily research- oriented and as such affect the amount and type of source reduction that can be achieved at this facility. The objective of ANL's waste minimization program is to cost-effectively reduce all types of wastes, including hazardous, mixed, radioactive, and nonhazardous wastes. The ANL Waste Minimization Plan uses a waste minimization audit as a systematic procedure to determine opportunities to reduce or eliminate waste. To facilitate these audits, a computerized bar-coding procedure is being implemented at ANL to track hazardous wastes from where they are generated to their ultimate disposal. This paper describes the development of the ANL Waste Minimization Plan ...

Energy Technology Data Exchange (ETDEWEB)

Diagnostic capability of Fuji Computed Radiography (FCR) of the chest was compared to the conventional radiography (CoR) using regular film-screen system. FCR utilizers imaging plates of scanning laser stimulated luminescence. Visibility of 14 structures of the chest radiography was evaluated by 3 radiologists in 100 pairs of FCR and CoR which were taken at the same time with the same exposure factors. FCR was superior to CoR especially in observation of the mediastinum and areas behind the heart and diaphragm. The minor fissure was better seen on CoR. Superiority of FCR to CoR was thought to be mainly due to the processed image of FCR, and the so-called normal image of FCR had little diagnostic advantage. Simulated abnormal densities: nodular, alveolar, and interstitial densities with a chest phantom, were made, and detectability of alteration of these densities on FCR and CoR was evaluated by 19 radiologists, using ROC curve analysis. FCR and CoR revealed the ...

Wastenet

governance through land use planning and mechanisms to deal with informal urban settlements in a manner that will facilitate improvements in

Energy Technology Data Exchange (ETDEWEB)

The production of oil by retorting shale and other hydrocarbonaceous and lignocellulosic solid materials is facilitated by retorting in the presence of steam and acetic acid.

International Nuclear Information System (INIS)

Inhaled beryllium oxide results in impaired alveolar clearance of inhaled "2"3"9PuO_2 and induces an inflammatory reaction in the lung. However, only one of 184 rats exposed to beryllium developed a lung tumor; none of 128 unexposed rats developed a lung tumor. Fifty-six lung tumors were induced in 181 rats exposed to plutonium. A total of 37 lung tumors were found in 119 rats given combined exposures to beryllium and plutonium. Only in rats given the highest levels of both beryllium and plutonium was there an incidence of lung tumors greater than that seen with exposure to plutonium only.

Energy Technology Data Exchange (ETDEWEB)

Research commenced in FY 97 to determine the suitability of superplasticized cement-sand grouts for backfilling vertical boreholes used with geothermal heat pump (GHP) systems. The overall objectives were to develop, evaluate and demonstrate cementitious grouts that could reduce the required bore length and improve the performance of GHPs. This report summarizes the accomplishments in FY 98. The developed thermally conductive grout consists of cement, water, a particular grade of silica sand, superplasticizer and a small amount of bentonite. While the primary function of the grout is to facilitate heat transfer between the U-loop and surrounding formation, it is also essential that the grout act as an effective borehole sealant. Two types of permeability (hydraulic conductivity) tests was conducted to evaluate the sealing performance of the cement-sand grout. Additional properties of the proposed grout that were investigated include bleeding, ...

Energy Technology Data Exchange (ETDEWEB)

The automotive paints could be generally differentiated by color, layer sequence and chemistry of the paint layers comprising each of the topcoat and the primer system. The successful identification of hit-and-run a and traffic accidental vehicles from evidential paint fragments is greatly facilitated with a comprehensive laboratory collection of reference paint samples and the technique for direct analysis without sample preparation. The Pyrolysis-Gas Chromatography(PGC) is a precise and reliable method for performing both quantitative and qualitative analysis of polymeric materials and forensic samples. Our Forensic Laboratory is conducting the examination and identification of 73 reference paint samples; 4 colors of each domestic automotive make that is poplar in Korea, by Curie Point Pyrolyzer(JHP-3) and GC with capillary column(ultra alloy-5). This method can be used not only to compare paint traces with their suspected sources, but also to identify the ...

Energy Technology Data Exchange (ETDEWEB)

Investigations of alternative renewable energy resources continue, with many studies concentrating on hydrogen storage. However, there are a few problems such as storage, transportation, delivery to the user and usage safely, to be addressed to facilitate commercialization and wide usage of the hydrogen. The absorbed form within the metal hydrides seems to be the best solution of this problem. Since Li is the lightest metal, it has the advantage as the stored amount of hydrogen mass ratio. LiBH{sub 4} production process was investigated using elemental Li, B and H{sub 2}. Spex type ball milling with tungsten carbide, stainless steel and zirconia type vessels, was used to mix the different amount of Li and B under argon atmosphere. X-ray diffraction pattern demonstrated that the LiB was obtained. A system was designed to provide a hydrogen atmosphere of 60 bars to force hydrogen into the LiB structure. FTIR analysis strongly ...

UK PubMed Central (United Kingdom)

BackgroundIncrease in the incidence of hyperuricemia associated with gout as well as hypertension, renal diseases and cardiovascular diseases has been a public health concern. We...Full Text Available

UK PubMed Central (United Kingdom)

The receptor-associated protein (RAP) is a molecular chaperone that binds tightly to certain newly synthesized LDL receptor family members in the endoplasmic reticulum (ER) and facilitates their delivery...Full Text Available

Science.gov (United States)

Recent Reviews in Carcinogenesis is a service of the International Cancer Research Data Bank (ICRDB) Program of the National Cancer Institute, intended to facilitate and promote the exchange of information between cancer scientists. It contains abstracts ...

Science.gov (United States)

... Society Physics Press Release 05-175Korea Joins International Computing Infrastructure ... connectivity with Korea in a ceremony last month. Facilitated by the Korea Institute for Science and ...

Energy Technology Data Exchange (ETDEWEB)

Previous studies suggest that the radiosensitivity and origin of tissue macrophage precursors differ from those of hemopoietic macrophage colony-forming units (CFU-Ms) committed to macrophage-lineage cells. We assessed the origins of tissue macrophage colony-forming cells (M-CFCs) in mice by comparing their kinetics and radiosensitivities in the normal steady state and under the conditions of bone marrow depletion by [sup 89]Sr-administration and/or splenectomy. The results indicate that the radiosensitive peritoneal M-CFCs elicited by thioglycollate are derived from bone marrow macrophage precursors; where as alveolar M-CFCs, which are radioresistant, are self-sustained locally and independent of hemopoietic macrophage precursors. In contrast, highly radiosensitive liver M-CFCs are probably derived from CFU-Ms that appear to be propagated in the spleen in association with hemopoietic responses. (author).

Energy Technology Data Exchange (ETDEWEB)

The translocation of particles from the alveolar compartment to the pleural space and tracheobronchial lymph nodes was investigated in rats over a 30 day period following the intrapulmonary instillation of 4 x 10/sup 8/ polystyrene microspheres (1.9 ..mu..m dia.). In initial studies, approx. =10/sup 4/ particles were found in the pleural space compartment on Days 1, 14 and 30 after particle deposition, and most of these were cell-associated. Subsequent pleural space studies indicated, however, that the particles found in this compartment were, at least in part, due to the pleural lavage technique, and, unlike observations reported for some fibers, the translocation of the particles used in our study to the pleural space does not represent an important lung clearance pathway. In regard to particle clearance to the tracheobronchial lymph nodes, the accumulation of particles, most of which were extracellular, kinetically was biphasic with the most rapid phase ...

Energy Technology Data Exchange (ETDEWEB)

Satellite imagery is a cost-effective tool for creating and updating basemaps of coastal zones, especially where existing maps and aerial photographs are unavailable, are out-of-date, or provide limited information. Reliable maps of coastal zones are particularly important for oil spill modelling programs. Color IR (multispectral) images with 20m x 20m ground resolution and black & white (panchromatic) images with 10m x 10m ground resolution of many coastlines around the globe have been acquired from 1986 to present by SPOT Image Corporation. We have digitally merged same-day SPOT panchromatic and multispectral imagery to provide maximum spatial resolution and permit excellent color differentiation of coastal zone features. This combination adequately discriminates individual features, including pipelines, offshore platforms, storage tanks, jetties, and shoreline type. The SPOT images were interpreted within a workstation environment and the coastline ...

Energy Technology Data Exchange (ETDEWEB)

This bibliography contains abstracts relating to various aspects of ALARA program implementation and dose reduction activities, with a focus on DOE facilities. Abstracts included in this bibliography were selected from proceedings of technical meetings, journals, research reports, searches of the DOE Energy, Science and Technology Database (in general, the citation and abstract information is presented as obtained from this database), and reprints of published articles provided by the authors. Facility types and activities covered in the scope of this report include: radioactive waste, uranium enrichment, fuel fabrication, spent fuel storage and reprocessing, facility decommissioning, hot laboratories, tritium production, research, test and production reactors, weapons fabrication and testing, fusion, uranium and plutonium processing, radiography, and aocelerators. Information on improved shielding design, decontamination, containments, robotics, source prevention ...

Energy Technology Data Exchange (ETDEWEB)

Improving software for the analysis of fenestration product energy efficiency and developing related information technology products that aid in optimizing the use of fenestration products for energy efficiency are essential steps toward ensuring that more efficient products are developed and that existing and emerging products are utilized in the applications where they will produce the greatest energy savings. Given the diversity of building types and designs and the climates in the U.S., no one fenestration product or set of properties is optimal for all applications. Future tools and procedures to analyze fenestration product energy efficiency will need to both accurately analyze fenestration product performance under a specific set of conditions and to look at whole fenestration product energy performance over the course of a yearly cycle and in the context of whole buildings. Several steps have already been taken toward creating fenestration product software ...

Energy Technology Data Exchange (ETDEWEB)

Untreated landfill leachates and wastes from metal plating and mining operations are sources of environmental contamination by heavy metals. Because of their toxicity and potential for accumulation, the discharge of heavy metals must be controlled. Standard physical and chemical treatments used to remove metals from wastes such as concentration by electro-precipitation, ion exchange, solvent extraction, evaporative recovery, and conventional precipitation, are usually expensive and produce high quantities of sludge. Biosorption is the removal of metals from aqueous solutions by microorganisms. It is called biosorption rather than bioadsorption or bioaccumulation because the mechanisms of removal are not restricted to adsorption or metabolic uptake and so the more general term is preferable and has come to be accepted. In this thesis the focus is one two microorganisms and two metals. However, the possible combinations of conditions such as pH, relative metal molarities, time of ...

International Nuclear Information System (INIS)

Throughout the last decades, plasma technology has been established in a series of surface treatment applications, e.g. for semiconductor processing or optical coatings. The majority of plasma assisted technologies is based on low pressure processes. In recent years, however, non-thermal atmospheric pressure discharges have attracted considerable interest because of their simplified technical devices for industrial applications as compared to low pressure processes which require vacuum equipment. Hence, batch processing can be avoided, thus facilitating the implementation of plasma process steps into production lines. Investment costs are cut down significantly. The use of atmospheric pressure plasmas for technical applications dates back to the ozone production with dielectric barrier discharges (DBD) by Siemens in 1857. Lately, the application of atmospheric pressure plasmas for surface treatment has been reported, e.g. for the treatment of foils to improve ...

UK PubMed Central (United Kingdom)

chipD is a web server that facilitates design of DNA oligonucleotide probes for high-density tiling arrays, which can be used in a number of genomic applications such as ChIP-chip or gene-expression...Full Text Available

UK PubMed Central (United Kingdom)

Replication of plus-strand RNA viruses depends on host factors that are recruited into viral replicase complexes. Previous studies showed that eukaryotic translation elongation factor (eEF1A) is one...Full Text Available

UK PubMed Central (United Kingdom)

Peripheral subunit binding domains (PSBDs) are integral parts of large multienzyme complexes involved in carbohydrate metabolism. PSBDs facilitate shuttling of prosthetic groups between different catalytic...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The demand for cogeneration plants is growing worldwide. For the combination of electricity generation and heat extraction in power stations facilitates an excellent fuel exploitation and makes the operator of the plant independent from external energy suppliers. (orig.)

UK PubMed Central (United Kingdom)

A general method is described to sequester peptides containing azides from complex peptide mixtures, aimed at facilitating mass spectrometric analysis to study different aspects of proteome...Full Text Available

UK PubMed Central (United Kingdom)

The widespread use of tobacco and alcohol among adolescents might be related to the ability of nicotine and ethanol to facilitate social interactions. To investigate the neurobehavioral mechanisms...Full Text Available

UK PubMed Central (United Kingdom)

The exposure of cells to several metal ions stabilizes HIF-1α protein. However, the molecular mechanisms are not completely understood. They may involve inhibition of hydroxylation by either...Full Text Available

UK PubMed Central (United Kingdom)

Lepidoptera, butterflies and moths, is the second largest animal order and includes numerous agricultural pests. To facilitate comparative genomics in Lepidoptera, we isolated BAC clones containing...Full Text Available

UK PubMed Central (United Kingdom)

This paper describes Image Engine, an object-oriented, microcomputer-based, multimedia database designed to facilitate the storage and retrieval of digitized biomedical still images, video, and text...Full Text Available

UK PubMed Central (United Kingdom)

RATIONALE AND OBJECTIVESNon-invasive longitudinal imaging of tumor vasculature could provide new insights into the development of solid tumors, facilitating efficient...Full Text Available

UK PubMed Central (United Kingdom)

The continuous addition of toluene as a solute of treated ballast water from oil tankers into a well-defined estuary facilitated the study of the dynamics of dissolved hydrocarbon metabolism in seawater....Full Text Available

UK PubMed Central (United Kingdom)

Polypeptides exiting the ribosome must fold and assemble in the crowded environment of the cell. Chaperones and other protein homeostasis factors interact with newly translated polypeptides to facilitate...Full Text Available

UK PubMed Central (United Kingdom)

Psychopathic individuals are generally unresponsive to motivational and emotional cues that facilitate behavioral regulation. A putative mechanism for this deficiency is Gray’s (1971)...Full Text Available

UK PubMed Central (United Kingdom)

Gene expression from bacterial artificial chromosome (BAC) clones has been demonstrated to facilitate physiologically relevant levels compared to viral and nonviral cDNA vectors. BACs are large enough...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundGenomics has substantially changed our approach to cancer research. Gene expression profiling, for example, has been utilized to delineate subtypes of cancer, and facilitated...Full Text Available

UK PubMed Central (United Kingdom)

Abs facilitate humoral immunity via the classical mechanisms of opsonization, complement activation, Ab-dependent cellular cytotoxicity, and toxin/viral neutralization. There is also evidence that some...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The distribution of lead in lactating mice and suckling offspring was studied with whole body autoradiography at 4 and 24 h after a single intravenous injection of {sup 203}Pb (50 mmol Pb/kg) to the dams. In the lactating mice on day 14 of lactation, the highest uptake of radioactivity at 4 h after administration was recorded in renal cortex, skeleton and liver. A high uptake was also evident in the mannary gland. At 24 h after administration, the radioactivity had decreased in most organs except in the skeleton. In the suckling pups, exposed to lead only via dams` milk for 24 h, the highest level of radioactivity was present in the intestinal mucosa and a much lower level of radioactivity was present in the skeleton. The mammary glands from mice given three daily intravenous injections of 240 {mu}mol Pb/kg were examined with X-ray microanalysis. At 4 h after the last injection, lead was found associated with casein micelles both inside the alveolar cell and in the ...

Science.gov (United States)

The influence of material configuration and impact parameters on the damage tolerance characteristics of sandwich composites comprised of carbon-epoxy woven fabric facesheets and Nomex honeycomb cores was investigated using empirically based response surfaces. A series of carefully selected tests were used to isolate the coupled influence of various combinations of the number of facesheet plies, core density, core thickness, impact energy, impactor diameter, and impact velocity on the damage formation and residual strength degradation due to normal impact. The ranges of selected material parameters were typical of those found in common aircraft applications. The diameter of the planar damage area associated with Through Transmission Ultrasonic C-scan measurements and the peak residual facesheet indentation depth were used to describe the extent of internal and detectable surface damage, respectively. Standard analysis of variance techniques were used to assess the significance of the ...

British Library Electronic Table of Contents (United Kingdom)

With the advent of computer technology, researchers and instructors are attempting to devise computer support for effective collaborative technical writing. In this study, a computer-supported environment for collaborative technical writing was developed. This system (Process-Writing Wizard) provides process-oriented scaffolds and a synchronous online chat room to facilitate real-time collaborative writing practice. It allows multiple students to work synchronously on collaborative writing tasks via the Internet. It also helps develop collaborative writing strategies, such as creating team agendas, brainstorming, creating team outlines, and generating team articles. An experiment was conducted to examine the effect of the system on EFL (English as a Foreign Language) students? collaborativ...

British Library Electronic Table of Contents (United Kingdom)

In many species social behaviors are dependent on integration of chemosensory and hormonal cues. Many chemosensory stimuli are detected by the vomeronasal organ, which projects to many regions that contain steroid receptors, including the medial amygdala. In male hamsters, testosterone is known to acutely increase in response to chemosensory stimulation, and can facilitate sexual behavior by direct action within the medial amygdala. Conspecific stimuli activate the anterior (MeA) and posterior (MeP) medial amygdala, while heterospecific stimuli activate only MeA. Chemosensory stimuli with different social significance differentially activate the dorsal and ventral subdivisions of MeA and MeP. Therefore, it is likely that steroids differentially facilitate stimulation of the medial amygdala...

Energy Technology Data Exchange (ETDEWEB)

The R and D activities of the institute focused on two major projects, ``Molecular and cellular environmental toxicology``, and ``Biophysics of multi-cellular systems``. For assessment of health risks emanating from the uptake of heavy metal compounds, work performed under the first mentioned project studies the formation of allergy-inducing metabolic products from membrane lipids, and the effects of related cellular signaling processes. These studies are accompanied by an approach to quantify and classify the toxicity of environmental organometallic compounds. Another major task is research into the pathogenesis of lung disease induced by dusts, gases, and gas-dust mixtures and the liberation of inflammatory agents by immunological cell reactions (alveolar macrophages). Atomic force microscopy is the tool used to visualize the related dynamic changes in bronchial cells. Studies for detection of the localisation and structure of the Fe-Mo co-factor in nitrogenase ...

Science.gov (United States)

A preliminary database has been developed that will allow mineralogy and bulk-rock geochemical information to be managed under configuration control and facilitate electronic querying. The database is currently developed in Microsoft Access as a collection of tables, views, and entry forms. Each field and table has been described in a data dictionary.

UK PubMed Central (United Kingdom)

Intimin facilitates intestinal colonization by enterohemorrhagic Escherichia coli O157:H7; however, the importance of intimin binding to its translocated receptor (Tir) as opposed to...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

A tiered communications architecture for managing network traffic in a distributed system. Communication between client or control computers and a plurality of hardware devices is administered by agent and monitor devices whose activities are coordinated to reduce the number of open channels or sockets. The communications architecture also improves the transparency and scalability of the distributed system by reducing network mapping dependence. The architecture is desirably implemented in a proton beam therapy system to provide flexible security policies which improve patent safety and facilitate system maintenance and development.

Energy Technology Data Exchange (ETDEWEB)

Norad commissioned Econ Poeyry to map teaching and research activities and capacity related to clean energy in selected Ethiopian universities. The mapping identified challenges and opportunities with the aim of facilitating future intervention by the Ethiopian Government and donors to help improve the energy sector development of the country. The report covered the government-owned universities of Bahir Dar, Mekelle, Jimma, Arba Minch and Addis Ababa. The mapping was based on a questionnaire and on interviews at each university. (Author)

Science.gov (United States)

A cryostat is described that was developed for irradiating a number of small metal specimens with a high beamcurrent of heavy particles at liquid nitrogen temperature. The specimens, which are mounted on a block, are taken out of the cryostat after irradiation and subsequently annealed in a temperature bath. The progress of annealing is followed by measuring the change in electrical resistivity of the specimens in liquid helium. (auth)

Energy Technology Data Exchange (ETDEWEB)

Revisions at steam turbines should present a problem-free procedure due to the long use of these machines. Changes in the market result in difficulties during the inspection work. The shortage of qualified personnel and manufacturing capacities are the cause for these difficulties. Important procedures of revisions are described in detail in the VGB regulations. Direct contacts between the customers and the suppliers facilitate the expirations substantially. In the case of good planning and under consideration of the well-known regulations, a revision can be accomplished to the satisfaction of customers and suppliers.

Science.gov (United States)

Describes the Indonesian system of education of Islamic schooling, secular education, and out-of-school education. The provision of 9-year universal basic education is planned by 2004. The national plan challenges the education system to facilitate the change in Indonesia's economic structure from an agriculturally based system to one more dependent on manufacturing and service industries. (SLD)

International Nuclear Information System (INIS)

Response of control valves plays an important role in the dynamics of the flow system as a whole. Knowledge of its transfer function would facilitate analysis of the behaviour of the system. This paper presents the application of Levy's complex curve fitting method for determination of the transfer function of control valves used in Liquid Zone Control System of 540 MWe PHWR. (author)

Energy Technology Data Exchange (ETDEWEB)

Computer tomography used in the diagnosis of tumours is described in the light of particularly great diagnostic difficulties in children. Computer tomography was applied in 12 cases. A high diagnostic value of this method was demonstrated, which makes possible a more accurate diagnosis of the position of the tumour, its size, and expanding tendency. The possibility of estimating healthy tissues and organs, and those with pathological changes on the basis of differences in their density with a detection threshold at 0.5% density difference facilitates not infrequently preoperative diagnosis raising the value of the method.

Energy Technology Data Exchange (ETDEWEB)

The Atlantic Wind Test Site was established in 1980 as a laboratory to facilitate the evaluation and demonstration of wind energy systems and equipment. This annual report describes its organization and management, facilities, major projects, and the outlook for the future. Major projects include wind diesel; AWTS-IREQ collaboration; remote community data acquisition; lagerwey test program; Alaska Energy Authority Project; public education; Atlantic Orient Corporation 15/50 Project; and the soft VAWT project.

Energy Technology Data Exchange (ETDEWEB)

The feasibility of using desferrioxamine (DF), an iron chelator, as a therapeutic agent against paraquat (PQ/sup + +/) toxicity in male Sprague-Dawley rats was explored, based on the rationale of limiting toxic hydroxyl radical production from hydrogen peroxide by removing redox-active iron. Body weights, mortality, and lung histopathology were followed for periods up to 14 days after intraperitoneal injection of PQ/sup + +/ (20 or 25 mg/kg body weight) with or without concurrent daily subcutaneous injections of DF (300 mg/day). Animals receiving PQ/sup + +/ showed the expected typical patterns of mortality and of lung histopathology, namely: marked edema, subpleural hemorrhage, acute inflammation, perivascular mononuclear cell infiltrates, sloughing of alveolar and bronchiolar lining cells, and diffuse interstitial fibrosis. Desferrioxamine alone was non-toxic. Surprisingly, results when both PQ/sup + +/ and DF were administered indicated a failure of DF to ...

International Nuclear Information System (INIS)

Pollen morphology of 30 species of the family Acanthaceae belonging to 11 genera has been investigated using light and scanning electron microscope. Acanthaceae is a eurypalynous family. Pollen are usually radially symmetrical, isopolar, sub-prolate to prolate rarely prolate-spheroidal or sub-oblate to oblate-spheroidal, generally tricolporate or heterocolporate rarely colpate or porate. Exine ornamentation varies from medium to coarse reticulate, or often lopho-reticulate with luminae perforated to baculate or scabrate. On the basis of apertural type, exine ornamentation and colpal membrane eight distinct pollen types have been recognized viz., Pollen type-I: Barleria cristata-type, Pollen type-II: Blepharis ciliaris-type, Pollen type-III: Hygrophila polysperma - type, Pollen type-IV: Justicia ...

International Nuclear Information System (INIS)

In the early sixties it was decided to investigate salt formations on its suitability to host heat generating radioactive waste in Germany. In the reference repository concept consequently the emplacement of vitrified waste canisters in deep vertical boreholes inside a salt mine was considered whereas spent fuel should be disposed of in self shielding casks (type POLLUX) in horizontal drifts. The POLLUX casks, 65 t heavy carbon steel casks, will be laid down on the floor of a horizontal drift in one of the disposal zones to be constructed in the salt dome at the 870 m level. The space between casks and drift walls will be backfilled with crushed salt. The transport, the handling und the emplacement of POLLUX casks were subject of successfully performed demonstration and in situ tests in the nineties and resulted in an adjustment of the atomic law. The borehole disposal concept comprises the emplacement of unshielded canisters with vitrified HLW in boreholes with a ...

KoreaScience (Korea)

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KoreaScience (Korea)

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International Nuclear Information System (INIS)

... Natural convection cooling of the channel type reactor performed with the fuel

CERN Document Server

We study a model for a protein searching for a target, using facilitated diffusion, on a DNA molecule confined in a finite volume. The model includes three distinct pathways for facilitated diffusion: (a) sliding - in which the protein diffuses along the contour of the DNA (b) jumping - where the protein travels between two sites along the DNA by three-dimensional diffusion, and finally (c) intersegmental transfer - which allows the protein to move from one site to another by transiently binding both at the same time. The typical search time is calculated using scaling arguments which are verified numerically. Our results suggest that the inclusion of intersegmental transfer (i) decreases the search time considerably (ii) makes the search time much more robust to variations in the parameters of the model and (iii) that the optimal search time occurs in a regime very different than that found for models which ignore intersegmental transfers. The ...

Energy Technology Data Exchange (ETDEWEB)

We propose triplet superconductors, such as ruthenates, as prospective materials for qubit construction. The vectorial nature of the order parameter in triplet superconductors makes it conceptually easy to estimate the performance of the qubits. The Cooper condensate of pairs in triplet superconductors has all the attributes of Bose-Einstein condensates and should facilitate long decoherence times for these qubits, relative to other vectorial schemes for qubits, such as small ferromagnets. There are other benefits, which the superconducting state provides for requirements such as entanglement between qubits via the proximity effect, etc. We consider these benefits in detail, although our consideration is only preliminary and further experimental and theoretical research will undoubtedly introduce correctives.

British Library Electronic Table of Contents (United Kingdom)

According to Schumpeter, the creative process of economic development can be divided into the stages of invention, innovation (commercialization) and imitation. Each stage is associated with specific skills. This paper examines whether Schumpeter?s assertion was correct, i.e. whether the invention and innovation stages should be undertaken by different agents. In addition, we examine whether there is a rationale for the Schumpeterian entrepreneur to include the inventor in the commercialization process. Combining the abilities of the entrepreneur and the inventor may serve to facilitate customer adaptation, strengthen knowledge transfers and reduce uncertainty, thereby expanding market opportunities. Based on a unique database covering Swedish patents granted to individuals and small firms...

Energy Technology Data Exchange (ETDEWEB)

Surface doping of conjugated polymers is realized by depositing a thin layer of graphene oxide (GO) on top of the polymers. The high proton density and the unique 2D structure of GO facilitate the protonic surface doping of conjugated polymers to achieve high conductivities. This finding represents a new strategy for improving charge transport across the metal/conjugated polymer interface to achieve much improved performance in organic solar cells. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

International Nuclear Information System (INIS)

By treatment with beta or gamma rays, PTFE waste is converted to high-grade PTFE fine powder. High-molecular weight PTFE is degraded to low-molecular weight PTFE. Due to this the density, the degree of crystallinity, and the melt flow index are increased, which enhances the brittleness of the material. Irradiation of PTFE thus facilitates milling and makes the material pourable and free-flowing. Milled PTFE fine powder, lie PTFE plastic, combines temperature resistance, weather fastness, and chemical stability with good slip behaviour and antiadhesive properties. Areas of application for fine powder include additives for plastics, printing inks, nonstick coatings, and antifriction lacquers. (orig.).

Energy Technology Data Exchange (ETDEWEB)

Hydrogen piston engines can be simultaneously optimized for improved thermal efficiency and for extremely low emissions. Using these engines in constant-speed, constant-load systems such as series hybrid-electric automobiles or home cogeneration systems can result in significantly improved energy efficiency. For the same electrical energy produced, the emissions from such engines can be comparable to those from natural gas-fired steam power plants. These hydrogen-fueled high-efficiency, low-emission (HELE) engines are a mechanical equivalent of hydrogen fuel cells. HELE engines could facilitate the transition to a hydrogen fuel cell economy using near-term technology.

Energy Technology Data Exchange (ETDEWEB)

Microorganisms are ubiquitous in subsurface environments although their populations sizes and metabolic activities can vary considerably depending on energy and nutrient inputs. As a result of their metabolic activities and the chemical properties of their cell surfaces and the exopolymers they produce, microorganisms can directly or indirectly facilitate the biotransformation of radionuclides, thus altering their solubility and overall fate and transport in the environment. Although biosorption to cell surfaces and exopolymers can be an important factor modifying the solubility of some radionuclides under specific conditions, oxidation state is often considered the single most important factor controlling their speciation and, therefore, environmental behavior.

International Nuclear Information System (INIS)

The atlas presents sequences of MRI sections parallel to the orbito-meatal plane in children from birth through the age of sixteen years. Each child was studied horizontally and sagitally and three-dimensional brain images were reconstructed to facilitate accurate identification of sulci and gyri. The images show crucial aspects of brain development such as the constancy of the brain stem and primitive brain from birth onward; the development of the telencephalon, characterized by deepening of sulci and growth of the cerebral cortex surface; and the different stages of white matter myelinization.

British Library Electronic Table of Contents (United Kingdom)

Resonant scattering of atoms with formation of the Feshbach resonance in the presence of a laser radiation coupling the levels of two bound atoms (a molecule) is considered. The laser field leads to a second resonance in scattering and broadening of resonances, which facilitates the possibility of experimental observation of asymmetry of the total scattering cross-section arising because of interference between resonant and potential scatterings. The effects associated with interference of the two channels of decay of a bound system of two atoms (a molecule) in the laser field are studied. An expression is obtained for the scattering length in collision of two cold atoms in the field of laser radiation.

International Nuclear Information System (INIS)

This is the first report about a relevant and compiled information on the Mexican Energy Sector. It was realized in one volume by the University Energy Program of the National Autonomous University of Mexico and it comprises information for the period 1996-1997. In the chapter 1 there are presented the numbers of hydrocarbon reserves. Chapter 2 treats about production, events and its results. Likewise chapter 3 shows information about the typical Installations for petroleum, gas and electricity including through of the nuclear energy. In the chapter 4, named Energy Consumption, is presented a National energy balance for 1996 and, finally there are a sections about the prices, the rates and a glossary to facilitate its understanding. (Author)

Science.gov (United States)

Spinal cord stimulation (SCS) is frequently used for relief of chronic benign pain resistant to conservative therapies. Clinical practice suggests, at least in patients with failed back surgery syndrome (FBSS), the possibility that SCS significantly improves motor performances. We present here the case of a 41-years-old female patient with FBSS, who showed a clear improvement in muscle strength after SCS, persisting at 6-months follow-up. We speculate that the electrical stimulation of posterior columns could potentiate the caudal, segmental spinal reflexes resulting in a facilitation of motoneurons activation. PMID:16175150

Science.gov (United States)

Lanthanide-ion doped oxide nanoparticles were functionalized for use as fluorescent biological labels. These nanoparticles are synthesized directly in water which facilitates their functionalization, and are very photostable without emission intermittency. Nanoparticles functionalized with guanidinium groups act as artificial toxins and specifically target sodium channels. They are individually detectable in cardiac myocytes, revealing a heterogeneous distribution of sodium channels. Functionalized oxide nanoparticles appear as a novel tool particularly well adapted to long-term single-molecule tracking.

British Library Electronic Table of Contents (United Kingdom)

Purpose - The purpose of this paper is to place all of the contributions to this special issue into a theoretical framework and to highlight the role that the so-called "information age mindset" has in the facilitation of employability skills. Design/methodology/approach - The paper discusses the major themes of this special issue. Findings - Undergraduate students do see the importance of technological innovation in the classroom but they see the development of experiential or work-based skills to be more important. Practical implications - Future curriculum design should consider the expectations and attitudes of the modern day undergraduate student to ensure that potential employability is maximised. Originality/value - The findings are placed into the wider context of the emerging fiel...

British Library Electronic Table of Contents (United Kingdom)

The purpose of this study is to clarify the confusing nomenclature and pathogenesis of Developmental Facial Paralysis, and how it can be differentiated from other causes of facial paralysis present at birth. Differentiating developmental from traumatic facial paralysis noted at birth is important for determining prognosis, but also for medicolegal reasons. Given the dramatic presentation of this condition, accurate and reliable guidelines are necessary in order to facilitate early diagnosis and initiate appropriate therapy, while providing support and counselling to the family. The 30 years experience of our center in the management of developmental facial paralysis is dependent upon a thorough understanding of facial nerve embryology, anatomy, nerve physiology, and an appreciation of well...

Energy Technology Data Exchange (ETDEWEB)

Absorption with aqueous amine solvents is at present the most viable technology for CO{sub 2} capture. While this is a proven technology, efforts are ongoing to improve it in order to make it a more attractive technology for large scale use to reduce CO{sub 2} emissions. Finding solvents with better properties is one approach to improving the technology. In this thesis methods in computational chemistry are used to improve the understanding of the chemistry of CO{sub 2} absorption in amine-water systems. The work is also intended to provide models that can be used to predict the performance of new solvents. Such predictive models are intended to facilitate the screening for new solvents

Energy Technology Data Exchange (ETDEWEB)

The Coal Corporation of Victoria's mission is to initiate, facilitate and co-ordinate brown coal-based developments, other than for electricity generation, to provide maximum long-term benefits to Victoria including new jobs, new technology, new investment and new products, within sound environmental parameters. The marketing of brown coal products is vigorously undertaken to provide the financial and business base for the Corporation. This report contains a review of the Corporation's activities and achievements during 1989/90.

Science.gov (United States)

The first candidate rotavirus vaccine was a live attenuated oral vaccine made by the classical empirical method of serial passage of virus in tissue culture cells. Current tetravalent vaccine candidates that are in the final stages of efficacy testing in the United States were made by genetic reassortment. This article briefly highlights how advances in the basic understanding of the molecular biology of rotaviruses have facilitated vaccine development. New approaches for second-generation vaccines and improvements in vaccine efficacy based on further exploitation of the tools and knowledge of rotavirus molecular biology and pathogenesis are discussed. PMID:8752289

International Nuclear Information System (INIS)

Radiology departments often underestimate the importance of protecting medical data during transmission, including the precautions taken to ensure data protection. In teleradiology, transmitted as well as stored patient data have to be signed digitally according to the currently valid regulation (Roentgenverordnung, RoeV). The DICOM standard facilitates a digital signature. So far, medical image manufacturers only announced to support this security feature. We introduce a solution that extends the feature of digital signing to older modalities. (orig.)

International Nuclear Information System (INIS)

In this article is reviewed the role of Computed Tomography (CT) in thoracic complications following ortho topic liver transplantation (OLT). In a post-OLT population of 567 patients transplanted in the Italian institutions, 100 patients (17.6%) were examined with chest CT. It was reviewed data relative to the total number of examinations, clinical and/or radiographic indications, the CT technique-i.e., conventional (with (out) intravenous, i.v., contrast material) or high-resolution (HRCT). It also reviewed the radiologic patterns and their correlation with the other clinical, bronchoscopic and/or laboratory results. Of 152 chest CT examinations, 45 (29.6%) were performed because of clinical indications, 31 (20.4%) because of a radiographic abnormality, 64 (42.1%) because of clinical and radiographic abnormality, 64 (42.1%) because of clinical and radiographic indications, while in 12 cases (7.9%) the reasons were unknown; 133/152 (87.5%) examinations had been performed with ...

Energy Technology Data Exchange (ETDEWEB)

Red mud is generated as a by-product in the production of Al(OH){sub 3}/Al{sub 2}O{sub 3} from bauxite ore. In this study the pellet-type adsorbents have been made from the red mud, and their adsorption capacities of heavy metal ions have been tested. The pellet-type adsorbents were synthesized to utilize the excellent adsorption capacity of the powder-type adsorbent for industrial application. The pellet-type adsorbents were prepared by mixing several kinds of additives with the red mud. It is found that the pellet-type adsorbent, made by sintering a mixture of red mud (96.0 wt%), polypropylene (2.5 wt%), fly ash (0.5 wt%), and sodium meta-silicate (1.0 wt%) at 1200 deg.C for 30 minutes, has the highest adsorption capacity. In this work, the two kinds of pellet-type adsorbents (bead-type, crushed-type) were prepared. ...

UK PubMed Central (United Kingdom)

This study determined the phylogenetic groups and virulence factors of 37 Escherichia coli isolates producing types of CTX-M compared with those of 19 isolates producing different types...Full Text Available

UK PubMed Central (United Kingdom)

Wild-type viruses from the ViroLogic phenotype-genotype database were evaluated to determine the upper confidence limit of the drug susceptibility distributions, or “biological cutoffs,”...Full Text Available

UK PubMed Central (United Kingdom)

Clostridium perfringens type C isolates cause enteritis necroticans in humans or necrotizing enteritis and enterotoxemia in domestic animals. Type C isolates always produce alpha toxin...Full Text Available

International Nuclear Information System (INIS)

In general there are actually two different types of A-15 compounds (A_3B) whose superconducting properties depend on whether the B atoms are transition elements (s-d type) or nontransition elements (s-p type). The properties in which the s-d type superconductors show marked differences in behavior from the s-p type include: (1) stoichiometry and range of composition, (2) the strong influence of N(O) on the stability and T/sub c/ of the phase, and (3), the effect of composition and atomic ordering on the T/sub c/ of the phase. These differences are discussed and a conclusion presented.

International Nuclear Information System (INIS)

We consider the dynamics toward the initial singularity of Bianchi type IX vacuum and orthogonal perfect fluid models with a linear equation of state. The 'Bianchi type IX attractor theorem' states that the past asymptotic behavior of generic type IX solutions is governed by Bianchi type I and II vacuum states (Mixmaster attractor). We give a comparatively short and self-contained new proof of this theorem. The proof we give is interesting in itself, but more importantly it illustrates and emphasizes that type IX is special, and to some extent misleading when one considers the broader context of generic models without symmetries.

Medline Plus

... United States, there are 14 million people with diabetes and while most will not lose their vision ... good deal higher among people with Type I diabetes -- the type that usually begins in childhood and ...

International Nuclear Information System (INIS)

... excursions fftf reactor fuel elements lmfbr type reactors reactivity insertions

Science.gov (United States)

We report a unique type of ULF waves observed by low-altitude Space Technology 5 (ST-5)

International Nuclear Information System (INIS)

The objective of this study was to determine the usefulness of parathyroid scintigraphy in histological estimation for secondary hyperparathyroidism (2HPT) using Tc-99m sestamibi or Tc-99m tetrofosmin. Tc-99m sestamibi (MIBI) and Tc-99m tetrofosmin (Tetro) parathyroid imaging following double-phase study, magnetic resonance imaging (MRI), and ultrasound were performed on 14 patients with 2HPT. All patients underwent parathyroidectomy. The uptake of two tracers in parathyroid areas was compared with the histopathologic findings. Forty-nine parathyroid glands were surgically explored and histologically proven to be hyperplastic. Of these, 42 were diagnosed with nodular type (N-type) hyperplasia, and 7 with diffuse type (D-type) hyperplasia. MIBI and Tetro parathyroid imagings detected 34 and 35 parathyroid glands, respectively. The sensitivity of MIBI was determined to be 76.2% (32/42) for ...

Energy Technology Data Exchange (ETDEWEB)

Value Engineering (VE) is a problem solving methodology that has been used in manufacturing and construction industries for fifty years to improve products, systems and projects while reducing unnecessary cost. A Process Waste Assessment (PWA) is a newly developed methodology designed to characterize waste streams and identify opportunities to reduce or eliminate waste generation. The VE and PWA methodologies are compared to show their general similarities and specific differences, and to suggest how VE can be woven into the PWA methodology. Further, the roles of the VE and PWA team leaders and their training are compared; suggestions are made to help enable the PWA team leader to more effectively lead a group-centered creative process. Examples of how VE has been used in hazardous and radioactive waste minimization and pollution prevention projects are presented, also.

British Library Electronic Table of Contents (United Kingdom)

Summary We describe the initiation and establishment of The University of Zambia - University College London Medical School (UNZA-UCLMS) Research and Training Project, an entirely African scientist-led, south-north partnership. In its 16 year existence, the project, by successfully obtaining competitive grant funding, has transformed itself into one of Africa's most productive African-led R&D programmes with training and visible research outputs. The project serves as a role model and now networks R&D and training activities with six southern African (10 institutions) and six European countries. This project case study illustrates that deep commitment is essential for success and that the factors which facilitate success in R&D in Africa need to be evaluated. The long-term prospects for su...

CERN Document Server

Non-linear realisations of the groups SU(2), SO(1,4) and SO(2,4) are analysed, described by the coset spaces SU(2)/U(1), SO(1,4)/SO(1,3) and SO(2,4)/SO(1,3) x SO(1,1). The Lie algebras of certain special unitary and special orthogonal groups are studied and their projection operators are determined in order to facilitate the above analyses, in particular that of SO(2,4)/SO(l,3) x SO(1,1). The analysis consists of determining the transformation properties of the Goldstone bosons, constructing the most general possible Lagrangian for the realisations and finding the metric of the coset space.

British Library Electronic Table of Contents (United Kingdom)

l-Carnitine is a critical metabolite indispensable for the metabolism of lipids as it facilitates fatty acid transport into the mitochondrion where b-oxidation occurs. Human astrocytes (CCF-STTG1 cells) and hepatocytes (HepG2 cells) exposed to aluminum (Al) and hydrogen peroxide (H2O2), were characterized with lower levels of l-carnitine, diminished b-oxidation, and increased lipid accumulation compared to the controls. g-Butyrobetainealdehyde dehydrogenase (BADH) and butyrobetaine dioxygenase (BBDOX), two key enzymes mediating the biogenesis of l-carnitine, were sharply reduced during Al and H2O2 challenge. Exposure of the Al and H2O2-treated cells to a-ketoglutarate (KG), led to the recovery of l-carnitine production with the concomitant reduction in ROS levels. It appears that the chann...

British Library Electronic Table of Contents (United Kingdom)

Abstract:- The demand for Lithium-ion batteries as a major power source in portable electronic devices and vehicles is rapidly increasing. I use cumulative data of vehicle, mobile phone, laptop, and digital camera production to show that demand will overshoot the available global Lithium resources before 2025. Even if 100% of all Lithium-ion batteries were recycled today, recycling could not prevent this resource depletion in time. As the increasing Lithium scarcity will increase the price, it will be feasible to mine diluted resources with a strong environmental impact. I highlight these impacts in Lithium-rich Bolivia, the potential new -Saudi Arabia of Lithium.- Lithium extraction is likely to cause substantial water pollution, and-through impacts on native diversity-facilitate human he...

British Library Electronic Table of Contents (United Kingdom)

Mono- and disubstituted novel derivatives of the heptaene nystatin analog 28,29-didehydronystatin A1 (S44HP, 1) were obtained by chemical modification of the exocyclic C-16 carboxyl and/or an amino group of mycosamine moiety. The strategy of preparation of mono- and double-modified polyene macrolides was based on the use of intermediate hydrophobic N-Fmoc (9-fluorenylmethoxycarbonyl) derivatives that facilitated the procedures of isolation and purification of new compounds. The antifungal activity of the new derivatives was first tested in vitro against yeasts and filamentous fungi, allowing the selection of the most active compounds that were subsequently tested for acute toxicity in mice. 2-(N,N-dimethylamino)ethylamide of 1 (2) and 2-(N,N-dimethylamino)ethylamide of N-fructopyranosyl-28...

British Library Electronic Table of Contents (United Kingdom)

The influence of selenium dioxide (SeO2) on the microstructure and electrodeposition of manganese coatings obtained from a sulfate based neutral solution was investigated by material characterization methods and electrochemical techniques. The crystal structure and surface morphology of these coatings were studied by scanning electron microscopy (SEM) and powder X-ray diffraction spectroscopy (XRD), respectively. The SEM and XRD data showed that SeO2 could effectively accelerate phase transformation, and facilitate leveled and fine grain growth. The electrochemical results indicated that SeO2 could inhibit hydrogen evolution reaction and promote manganese deposition. The action of selenium dioxide in manganese deposition was found to be a reduction and adsorption mechanism. The process cou...

British Library Electronic Table of Contents (United Kingdom)

Summary 1. In the Greater Yellowstone Ecosystem, bison Bison bison and elk Cervus canadensis nelsoni act as hosts for Brucella abortus. The presence of B. abortus within wildlife populations is an important conservation issue because of the risk of brucellosis transmission from wildlife to cattle. 2. We investigated conditions facilitating contact between bison (40-60% seroprevalence) and elk on a shared winter range in the Madison headwaters area of Yellowstone National Park. We evaluated the effects of snow pack, season, elk and bison population sizes, and wolf Canis lupus predation risk on the degree of spatial overlap between bison and elk from 1991 to 2006. 3. Sixty-eight per cent of 10 093 independent elk observations occurred within the known bison wintering range, 29% occurred with...

Energy Technology Data Exchange (ETDEWEB)

A geological and geotechnical framework was provided in order to facilitate understanding of the damage to structures resulting from soil conditions during the earthquake of January 17, 1995 at Hyogo-ken Nanbu (Kobe), Japan. Special attention was paid to the large scale failures of the quay walls in the port of Kobe, resulting from liquefaction. The performance of structures in improved and unimproved ground were compared. It was observed that locations with some previous site improvements through densification behaved satisfactorily, despite unanticipated high levels of ground motion. Soil-structure interaction problems, such as pile foundations, bridge piers, lifelines, and an underground subway station were also described. Reference was made to the significance of these failures for the seismic design in the Fraser Delta in British Columbia in view of the area`s proneness to liquefaction during a major earthquake. 31 refs., 5 tabs., 45 figs.

Energy Technology Data Exchange (ETDEWEB)

We report on the software aspects of the development of a switch-based data acquisition system at Fermilab. This paper describes how, with the goal of providing an integrated systems engineering'' environment, several powerful software tools were put in place to facilitate extensive exploration of all aspects of the design. These tools include a simulation package, graphics package and an Expert System shell which have been integrated to provide an environment which encourages the close interaction of hardware and software engineers. This paper includes a description of the simulation, user interface, embedded software, remote procedure calls, and diagnostic software which together have enabled us to provide real-time control and monitoring of a working prototype switch-based data acquisition (DAQ) system.

British Library Electronic Table of Contents (United Kingdom)

The paper seeks to illuminate everyday work practices in the economic spaces of Malaysia's business process outsourcing (BPO) industry. It draws upon empirical evidence from call centre staff and promotes analytical sensitivity to the experience of labour and spatiotemporal relations within the offshore back offices of multinational corporations located in Cyberjaya, Malaysia. The analysis provides an empirical snapshot of how IT-facilitated work practices in the global information economy are embedded and socially reproduced in everyday settings. To this end, the paper engages anthropologically with BPO labour, and critiques -globalist- representations of economic and social transformation frequently articulated through an abstract, dehumanized space of networks and flows often seen to wa...

Energy Technology Data Exchange (ETDEWEB)

Greenhouse-effect induced climate change repercussions will, via the catchment areas of big rivers, eventually arrive in amplified form at the far downstream coastal zones of the world. In the coastal zone these imported problems will add to the locally exerted climate change effects, while the climate change induced sea-level rise will attack the coastal zone from the other side, both by flooding and by saline groundwater intrusion. These multiple problems will hit the coastal zone, which is already under increasing stress. The combined threats require fast and massive support for national Coastal Zone Management capabilities, which could help to limit the damage and to support planning for sustainable development. Recommendations are presented to facilitate implementation of Coastal Zone Management units in all coastal countries by the year 2000.

Energy Technology Data Exchange (ETDEWEB)

The Pinellas Plant has been part of the Department of Energy`s (DOE) nuclear weapons complex since the plant opened in 1957. In March 1995, the DOE sold the Pinellas Plant to the Pinellas County Industry Council (PCIC). DOE has leased back a large portion of the plant site to facilitate transition to alternate use and safe shutdown. The current mission is to achieve a safe transition of the facility from defense production and prepare the site for alternative uses as a community resource for economic development. Toward that effort, the Pinellas Plant Environmental Baseline Report (EBR) discusses the current and past environmental conditions of the plant site. Information for the EBR is obtained from plant records. Historical process and chemical usage information for each area is reviewed during area characterizations.

CERN Document Server

The goal of this work is to minimize the energy dissipation of embedded controllers without jeopardizing the quality of control (QoC). Taking advantage of the dynamic voltage scaling (DVS) technology, this paper develops a performance-aware power management scheme for embedded controllers with processors that allow multiple voltage levels. The periods of control tasks are adapted online with respect to the current QoC, thus facilitating additional energy reduction over standard DVS. To avoid the waste of CPU resources as a result of the discrete voltage levels, a resource reclaiming mechanism is employed to maximize the CPU utilization and also to improve the QoC. Simulations are conducted to evaluate the performance of the proposed scheme. Compared with the optimal standard DVS scheme, the proposed scheme is shown to be able to save remarkably more energy while maintaining comparable QoC.

International Nuclear Information System (INIS)

Positron emission tomography (PET) is the gold standard for non-invasive assessment of myocardial viability and allows accurate detection of coronary artery disease by assessment of myocardial perfusion. Magnetic resonance imaging (MRI) provides high resolution anatomical images that allow accurate evaluation of ventricular structure and function together with detection of myocardial infarction. Potential hybrid PET/MR tomography may potentially facilitate the combination of information from these imaging modalities in cardiology. Furthermore, the combination of anatomical MRI images with the high sensitivity of PET for detecting molecular targets may extent the application of these modalities to the characterization of atherosclerotic plaques and to the evaluation of angiogenetic or stem cell therapies, for example. This article reviews studies using MRI and PET in parallel to compare their performance in cardiac applications together with the potential benefits ...

British Library Electronic Table of Contents (United Kingdom)

Background Trauma centers are designated to provide systematized multidisciplinary care to injured patients. Effective trauma systems reduce patient mortality by facilitating the treatment of injured patients at appropriately resourced hospitals. Several U.S. studies report reduced mortality among patients admitted directly to a level I trauma center compared with those admitted to hospitals with less resources. It has yet to be shown whether there is an outcome benefit associated with the ?level of hospital? initially treating severely injured trauma patients in Australia. This study was designed to determine whether the level of trauma center providing treatment impacts mortality and/or hospital length of stay. Methods Outcomes were evaluated for severely injured trauma patients with an ...

Energy Technology Data Exchange (ETDEWEB)

One important factor frustrating optimal management of Department of Energy (DOE)-complex wastes is the inability to use licensed and permitted facilities systematically. Achieving the goal of optimal use of DOE`s waste management facilities is politically problematic for two reasons. First, no locale wants to bear a disproportionate burden from DOE wastes. Second, the burden imposed by additional wastes transported from one site to another is difficult to characterize. To develop a viable framework for equitably distributing these burdens while achieving efficient use of all DOE waste management facilities, several implementation and equity issues must be addressed and resolved. This paper discusses stakeholder and equity issues and proposes a framework for joint research and action that could facilitate equity negotiations among stakeholder and move toward a more optimal use of DOE`s waste management capabilities.

British Library Electronic Table of Contents (United Kingdom)

Summary Status epilepticus or other brain-damaging insults launch a cascade of events that may lead to the development of epilepsy. MRI techniques available today, including T2- and T1-weighted imaging, functional MRI, manganese enhanced MRI (MEMRI), arterial spin labeling (ASL), diffusion tensor imaging (DTI), and phase imaging, can detect not only damage caused by status epilepticus but also plastic changes in the brain that occur in response to damage. Optimal balance between damage and recovery processes is a key for planning possible treatments, and noninvasive imaging has the potential to greatly facilitate this process and to make personalized treatment plans possible.

Energy Technology Data Exchange (ETDEWEB)

The Low-Level Radioactive Waste Forum is an association of representatives of states and compacts established to facilitate state and compact commission implementation of the Low-Level Radioactive Waste Policy Act of 1980 and the Low-Level Radioactive Waste Policy Amendments Act of 1985 and to promote the objectives of low-level radioactive waste regional compacts. The Forum provides an opportunity for states and compacts to share information with one another and to exchange views with officials of federal agencies. The Forum participants include representatives from regional compacts, designated host states, unaffiliated states, and states with currently-operating low-level radioactive waste facilities. This report contains information synthesizing the accomplishments of the Forum, as well as any new advances that have been made in the management of low-level radioactive wastes.

British Library Electronic Table of Contents (United Kingdom)

Summary: Analysis of biological networks requires assessing the statistical significance of network-based predictions by using a realistic null model. However, the existing network null model, switch randomization, is unsuitable for metabolic networks, as it does not include physical constraints and generates unrealistic reactions. We present JMassBalance, a tool for mass-balanced randomization and analysis of metabolic networks. The tool allows efficient generation of large sets of randomized networks under the physical constraint of mass balance. In addition, various structural properties of the original and randomized networks can be calculated, facilitating the identification of the salient properties of metabolic networks with a biologically meaningful null model. Availability and Imp...

British Library Electronic Table of Contents (United Kingdom)

Recent supply chain reengineering efforts have focused on integrating firms? production, inventory and replenishment activities with the help of communication networks. While communication networks and supply chain integration facilitate optimization of traditional supply chain functions, they also exacerbate the information security risk: communication networks propagate security breaches from one firm to another, and supply chain integration causes breach on one firm to affect other firms in the supply chain. We study the impact of network security vulnerability and supply chain integration on firms? incentives to invest in information security. We find that even though an increase in either the degree of network vulnerability or the degree of supply chain integration increases the secur...

International Nuclear Information System (INIS)

A large portion of the work performed at nuclear power plants follows standardized flow paths. For example, although components on which the maintenance crew works differ from one assignment to the next, all assignments basically follow the same process: requesting, reviewing, planning, scheduling, executing, testing, and documenting the work. In general, the term open-quotes work processclose quotes is used to refer to a standardized sequence of tasks designed within the operational environment of an organization to achieve a specific goal. The predictable nature of work processes suggests that a systematic analysis can be conducted to identify the desirable design of the process and to develop performance measures with respect to the strengths and weaknesses in the process. Furthermore, because of the close relationship of the work process to plant performance and plant safety, it is believed that such an analysis will facilitate the inclusion of organizational ...

Energy Technology Data Exchange (ETDEWEB)

Consultant and advanced practice are relatively new concepts in radiography. There is evidence to show that as the career progression framework is being adopted the numbers of consultant and advanced practitioners in radiography are growing with the latter growing at a faster rate. The article considers the concept of advanced and consultant practice and the education requirements to support development. Preparation for an advanced practice role begins at the practitioner stage. Masters' level programmes are available to support the development of advanced practice. Education needs to be flexible as new advanced practice roles emerge. It is necessary to take practitioners beyond a defined modality to include leadership and people skills. These are essential for those aspiring to become consultants. Consultants require a high level of clinical knowledge for expert practice but also strategic vision and interpersonal intelligence to facilitate leadership and ...

British Library Electronic Table of Contents (United Kingdom)

Porous SnO2 nanotubes were prepared via electrospinning followed by calcination in air. As anode materials for lithium ion batteries, the porous nanotubes delivered a high discharge capacity of 807mAhg^-^1 after 50cycles. Even after cycled at high rates, the electrode still retained a high fraction of its theoretical capacity. Such excellent performances of porous SnO2 nanotubes could be attributed to the porous and hollow structure which facilitated liquid electrolyte diffusion into the bulk materials and buffered large volume changes during lithium ions insertion/extraction. Furthermore, the nanoparticles of nanotubes provided the shorter diffusion length for lithium ions insertion which benefited in retaining the structural stability and good rate performance. Our results demonstrated t...

British Library Electronic Table of Contents (United Kingdom)

High molecular weight products of the ozonolysis reaction of particle-phase 9-octadecenoic acid (oleic acid) have been studied by photoelectron resonance capture ionization (PERCI) mass spectrometry (MS). Oleic acid particles ( Formula Not Shown , Formula Not Shown ) were reacted with ozone (1.8x10-4atm) in a flow reactor at reaction times of 8 and 23s. Particles were sampled on-line with a differentially pumped particle inlet and chemically analyzed by PERCI-MS. PERCI is a soft ionization method that permits the direct measurement of relatively high molecular weight compounds, facilitating molecular identification. In addition to cyclic oxygenates, such as secondary ozonides and geminal diperoxides that were reported previously, we demonstrate the formation of polymers at the particle sur...

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The evolution of these new ion-exchange resins hinges upon an understanding of the chemistry of actinide metal complexes as they exist in solution and when interacting with the cationic sites. Molecular modeling of electrostatic interactions between the metal complex and the cationic substrate is used to help visualize uptake mechanisms and, eventually, to predict optimized coordination sites. Thus, these new materials integrate the fields of ion-specific chelation and ion-exchange technology. Synthesized resins contain cationic sites designed to facilitate the uptake of plutonium nitrato complexes from high-nitrate solutions, and they exhibit distribution coefficients that are up to 10 times higher than those observed for commercial resins. Additionally, some new resins show surprisingly large Kd`s for anionic complexes of Am(III) and U(VI).

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The manual provides design information for four groups of sediment control structures and treatments which are suitable for use on small areas in surface coal mining. A detailed design procedure is given for each group which will estimate the total amount of settleable solids from a small area with a sediment control structure or treatment for a specific design storm. A procedure is also given for estimating the mean annual sediment yield from a small area. Information on design, installation, maintenance and cost is given for each sediment control measure. Methods for determining the maximum allowable area for each sediment control measure and for design of combined sediment control systems are presented. The design procedures contain numerous nomographs, graphs, and worksheets to facilitate the use of the design procedure. The sediment control measures, design procedures, and materials in the manual are applicable to coal-bearing regions of the continental United ...

International Nuclear Information System (INIS)

A non-contact method, using magnetic drag force principle, was proposed to design the braking systems to improve the shortcomings of the conventional braking systems. The extensive literature detailing all aspects of the magnetic braking is briefly reviewed, however little of this refers specifically to upright magnetic braking system, which is useful for industries. One of the major issues to design upright magnetic system is to find out the magnetic flux. The changing magnetic flux induces eddy currents in the conductor. These currents dissipate energy in the conductor and generate drag force to slow down the motion. Therefore, a finite element model is developed to analyze the phenomena of magnetic flux density when air gap and materials of track are varied. The verification shows the predicted magnetic flux is within acceptable range with the measured value. The results will facilitate the design of magnetic braking systems.

British Library Electronic Table of Contents (United Kingdom)

Background Photopolymerizable poly(ethylene glycol) (PEG) hydrogels offer a platform to deliver cells in vivo and support three-dimensional cell culture but should be designed to degrade in sync with neotissue development and endure the physiologic environment. Questions/purposes We asked whether (1) incorporation of degradation into PEG hydrogels facilitates tissue development comprised of essential cartilage macromolecules; (2) with early loading before pericellular matrix formation, the duration of load affects matrix production; and (3) dynamic loading in general influences macroscopic tissue development. Methods Primary bovine chondrocytes were encapsulated in hydrogels (n?=?3 for each condition). The independent variables were hydrogel degradation (nondegrading PEG and degrading olig...

International Nuclear Information System (INIS)

This report is based on a study carried out by the NEA Decommissioning Cost Estimation Group (DCEG) on decommissioning cost elements, estimation practices and reporting requirements. Its findings indicate that cost methodologies need to be updated continuously using cost data from actual decommissioning projects and hence, systematic approaches need to be implemented to collect these data. The study also concludes that changes in project scope may have the greatest impact on project costs. Such changes must therefore be identified immediately and incorporated into the estimate. Finally, the report notes that more needs to be done to facilitate the comparison of estimates, for example by providing a reporting template for national estimates. (authors)

International Nuclear Information System (INIS)

A conformational analysis of ethyl azidoformate (EAF) has been carried out by the MINDO/3 quantum-chemical method. It has been shown that EAF exists in the form of two conformers differing with respect to rotation around the C-N bond. Complete optimization of the geometry has been carried out for both conformers. It has been found that the transoid conformation is planar and that the cisoid conformation is nonplanar. The height of the rotation barrier is 15.4 kcal/mole. The optimal geometry of the transition state has been calculated. It has been noted that a significant role in the mechanism of the conformational transition is played by the inversion of a nitrogen, which facilitates the transition. The results of the calculation have been confirmed by IR-spectroscopic data.

International Nuclear Information System (INIS)

The plastic deformation behavior of formed CICC for the superconducting Tokamac fusion device was examined and appropriate manufacturing information was provided. A relation between travel of the bending roller and spring back displacement was obtained via virtual manufacturing. The radius of CICC after forming was expressed as a function of the bend-roll travel. The maximum von Mises stress after spring back was also monitored for the SAGBO prediction. Next, the variation of the CICC cross-sectional area was examined during the first turn and during conduit bending with the largest curvature. Finally, the coil radius was measured and compared with the data generated from the virtual manufacturing. The measured data showed similar pattern as predicted one. Using the mapping function found to match with the real data, the data from the virtual manufacturing may facilitate accurate manufacturing.

British Library Electronic Table of Contents (United Kingdom)

SummaryProcesses of upgrading and the promotion of industrial "clusters," which encompass multiple policies, institutions, and actors, necessarily vary from place to place. Based on the evidence from Morocco and Tunisia, this article contends that different patterns of business-government relations facilitate different elements of industrial upgrading and cluster promotion. State-dominated political economies may be more amenable to implementing macroeconomic and infrastructure-related measures, which are critical in the initial stages of upgrading. Political economies with more organized business communities may be better equipped to pursue the kinds of inter-firm linkages traditionally associated with later phases of upgrading, when the focus is on boosting innovation.

British Library Electronic Table of Contents (United Kingdom)

Research and bioethical policies are increasingly seen to facilitate, rather than to impede, scientific progress. Bioethical structures, nonetheless, often fail to account for or to shape the specific social surrounds in which scientific research is conducted. In Taiwan, a perceived shortage in human biological donations threatens to hamper stem cell research progress. This paper considers the stalled national biobank project and the lack of a reliable embryo supply for stem cell research, and suggests that one must look beyond regulatory structures in seeking explanations for such shortages. Specific aspects of Taiwan's democratization and social changes combine with problematic relations between patients and physicians to shape the terrain upon which human biologicals are given or withhe...

Energy Technology Data Exchange (ETDEWEB)

Fifty-nine patients underwent free flap osteocutaneous reconstruction that consisted of flaps of the dorsum of the foot in 26 patients and iliac crest flaps in 33 with a success rate of 92 percent and a mortality rate of 1.6 percent. These flaps, which require the expertise of microvascular surgeons, are time-consuming and complicate operating room and time management, but they represent a remarkable advance in reconstruction that can facilitate cosmetic and functional recovery of the patient. In particular, they promote healing in radiation-recurrent oral cancer and represent a definitive form of management for established radionecrosis of the mandible. The large volume of tissue available with iliac crest osteocutaneous grafts permits the management of patients with extensive cancer involving the skin, mucosa, and bone, but cancer control may still be disappointing and there is a need for improved adjuvant chemotherapy protocols. This technique appears to be a ...

Energy Technology Data Exchange (ETDEWEB)

A novel adaptive stabilizer, called an Adaptive Governor Power System Stabilizer (AGPSS), which operated on the governor turbine system, was described. There has been extensive research on adaptive excitation control of generators in power systems with the goal of achieving better dynamic performance. AGPSS tracks the frequency and damping of oscillations in a power system, and adjusts to ensure that there is always sufficient damping in the system. There is no interaction between stabilizers on different generating units, and each one acts independently, consuming oscillation energy locally. These stabilizers are easy to design and this facilitates their use in multimachine systems. Results obtained by nonlinear simulation of a single-machine and a three-machine power system were discussed, illustrating the effectiveness of the stabilizers in supplying damping and improving stability. It was pointed out that the operation of AGPSS does not conflict with that of ...

British Library Electronic Table of Contents (United Kingdom)

Hepatocellular carcinoma (HCC) represents a major health problem as it afflicts an increasing number of patients worldwide. Albeit most of the risk factors for HCC are known, this is a deadly syndrome with a life expectancy at the time of diagnosis of less than 1?year. Definition of the molecular principles governing the neoplastic transformation of the liver is an urgent need to facilitate the clinical management of patients, based on innovative methods to detect the disease in its early stages and on more efficient therapies. In the present study, we have combined the analysis of a murine model and human samples of HCC to identify genes differentially expressed early in the process of hepatocarcinogenesis, using a microarray-based approach. Expression of 190 genes was impaired in murine ...

Science.gov (United States)

One of the stiffest challenges in structural studies of proteins using NMR is the assignment of sidechain resonances. Typically, a panel of lengthy 3D experiments are acquired in order to establish connectivities and resolve ambiguities due to overlap. We demonstrate that these experiments can be replaced by a single 4D experiment that is time-efficient, yields excellent resolution, and captures unique carbon-proton connectivity information. The approach is made practical by the use of non-uniform sampling in the three indirect time dimensions and maximum entropy reconstruction of the corresponding 3D frequency spectrum. This 4D method will facilitate automated resonance assignment procedures and it should be particularly beneficial for increasing throughput in NMR-based structural genomics initiatives.

Medline Plus

... they're not from other things such as endometriosis and other types of polyps and tumors that ...

International Nuclear Information System (INIS)

Short communication.

KoreaScience (Korea)

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... the type locality on the Zaire River at Matadi, where it was first recorded in the 1940s ... ...

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... Congo, Guinea Equatorial, and Angola. The record from Matadi from the Lower Congo and the type locality ... ...

International Nuclear Information System (INIS)

... bwr type reactors closures fluidic control devices operation performance pwr

International Nuclear Information System (INIS)

... Abstract only 1063-7869 v. 44(10) CLASSICAL AND QUANTUM MECHANICS,

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Energy Technology Data Exchange (ETDEWEB)

Hybrid models for solving unit commitment problem have been proposed in this paper. To incorporate the changes due to the addition of new constraints automatically, an expert system (ES) has been proposed. The ES combines both schedules of units to be committed based on any classical or traditional algorithms and the knowledge of experienced power system operators. A solution database, i.e. information contained in the previous schedule is used to facilitate the current solution process. The proposed ES receives the input, i.e. the unit commitment solutions from a fuzzy-neural network. The unit commitment solutions from the artificial neural network cannot offer good performance if the load patterns are dissimilar to those of the trained data. Hence, the load demands, i.e. the input to the fuzzy-neural network is considered as fuzzy variables. To take into account the uncertainty in load demands, a fuzzy decision making approach has also been developed to solve the ...

International Nuclear Information System (INIS)

The p75 neurotrophin receptor (p75"N"T"R) is a death receptor which belongs to the tumor necrosis factor receptor super-family of membrane proteins. This study shows that p75"N"T"R retarded cell cycle progression by induced accumulation of cells in G0/G1 and a reduction in the S phase of the cell cycle. The rescue of tumor cells from cell cycle progression by a death domain deleted (#DELTA#DD) dominant-negative antagonist of p75"N"T"R showed that the death domain transduced anti-proliferative activity in a ligand-independent manner. Conversely, addition of NGF ligand rescued retardation of cell cycle progression with commensurate changes in components of the cyclin/cdk holoenzyme complex. In the absence of ligand, p75"N"T"R-dependent cell cycle arrest facilitated an increase in apoptotic nuclear fragmentation of the prostate cancer cells. Apoptosis of p75"N"T"R expressing cells occurred via the intrinsic mitochondrial pathway leading to a sequential caspase-9 and ...

International Nuclear Information System (INIS)

Fetal MRI can be performed in the second and third trimesters. During this time, the fetal brain undergoes profound structural changes. Interpretation of appropriate development might require comparison with normal age-based models. Consultation of a hard-copy atlas is limited by the inability to compare multiple ages simultaneously. To provide images of normal fetal brains from weeks 18 through 37 in a digital format that can be reviewed interactively. This will facilitate recognition of abnormal brain development. T2-W images for the atlas were obtained from fetal MR studies of normal brains scanned for other indications from 2005 to 2007. Images were oriented in standard axial, coronal and sagittal projections, with laterality established by situs. Gestational age was determined by last menstrual period, earliest US measurements and sonogram performed on the same day as the MR. The software program used for viewing the atlas, written in C, permits linked ...

Science.gov (United States)

PURPOSE We wanted to examine how coordinated care is implemented in primary care practices to address patients' health behavior change needs. METHODS Site visit notes, documents, interviews, and online implementation diaries were collected from July 2005 to September 2007 from practice-based research networks (PBRNs) participating in Prescription for Health: Promoting Healthy Behaviors in Primary Care Research Networks (P4H). An iterative group process was used to conduct a cross-case comparative analysis of 9 interventions. Published patient outcomes reports from P4H interventions were referenced to provide information on intervention effectiveness. RESULTS In-practice health risk assessment (HRA) and brief counseling, coupled with referral and outreach to a valued and known counseling resource, emerged as the best way to consistently coordinate and encourage follow-through for health behavior counseling. Findings from published P4H outcomes suggest that this approach led to ...

British Library Electronic Table of Contents (United Kingdom)

The type III secretion system among Gram-negative bacteria is known to deliver effectors into host cell to interfere with host cellular processes. The type III secretion system in Yersina, Pseudomonas and Enterohemorrhagic Escherichia coli have been well documented to be involved in the bacterial pathogenicity. The existence of type III secretion system has been demonstrated in neuropathogenic E. coli K1 strains. Here, it is observed that the deletion mutant of type III secretion system in E. coli strain EC10 exhibited defects in the invasion and intracellular survival in Acanthamoeba castellanii (a keratitis isolate) compared to its parent strain. Next, it was determined whether type III secretion system plays a role in E. coli K1 survival inside Acanthamoeba during the encystment process...

International Nuclear Information System (INIS)

The neutron transmutation doping (NTD) method was applied to the initially p-type silicon in order to extend the NTD applications at HANARO. The relationship between the irradiation neutron fluence and the final resistivity of the initially p-type silicon material was investigated. The proportional constant between the neutron fluence and the resistivity was determined to be 2.3473x1019 n ? cm-1. The deviation of the final resistivity from the target for almost all the irradiation results of the initially p-type silicon ingots was at a range from -5% to 2%. In addition, the burn-up effect of the boron impurities, the residual 32P activity and the effect of the compensation characteristics for the initially p-type silicon were studied. Conclusively, the practical methodology to perform the neutron transmutation doping of the initially p-type silicon ingot was established.

UK PubMed Central (United Kingdom)

Urethral duplication is a rare congenital anomaly of the lower urinary system and has varied presentation. According to the Effmann classification, type IIA2-Y urethral duplication is charcterized by...Full Text Available

UK PubMed Central (United Kingdom)

This study was undertaken to determine which rodent species serve as primary reservoirs for the Lyme disease spirochete Borrelia burgdorferi in commonly occurring woodland types...Full Text Available

UK PubMed Central (United Kingdom)

Recent reports confirm that, due to the presence of long-lived, latently infected cell populations, eradication of human immunodeficiency virus type 1 (HIV-1) from infected patients by using antiretroviral...Full Text Available

UK PubMed Central (United Kingdom)

Patients with Alport syndrome progressively lose renal function as a result of defective type IV collagen in their glomerular basement membrane. In mice lacking the α3 chain of type IV collagen...Full Text Available

UK PubMed Central (United Kingdom)

Bacteria expressing type III secretion systems (T3SS) have been responsible for the deaths of millions worldwide, acting as key virulence elements in diseases ranging from plague to typhoid...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

It is shown that within the framework of the Kershaw stochastic model generalized by the author to the relativistic case a Feynman-type process may be constructed which can formally be understood as a diffusion phenomenon in Euclidean space. This makes it possible to introduce a real probability measure in the scheme of quantum mechanics proposed by Feynman.

Energy Technology Data Exchange (ETDEWEB)

It is proven that there do not exist any diagonal Bianchi type-IX universes which expand for an infinite time, provided only that the matter satisfies the dominant energy condition and has non-negative average principal pressures.

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A composite is any combination of two or more resources held together by some type of mastic or matrix. This report will describe several different types of composites with regard to thermoplasticization, improved mechanical properties, and stiffness.

UK PubMed Central (United Kingdom)

OBJECTIVETo determine the association between 25-hydroxyvitamin D (25-OHD) concentration and risk of incident type 2 diabetes.RESEARCH DESIGN AND METHODSIn...Full Text Available

International Nuclear Information System (INIS)

In this paper, results on ozone production by atmospheric pulsed discharge, are reported. In the research, two types of ozonizer (Type I and Type II) have been used to investigate improvements of ozone concentration and production efficiency. The ozonizer has plane-to-plane metal electrodes structure, and pre-ionization electrodes are placed on the high voltage electrodes (Type I). In Type II, the surface of grounded electrode with 20 mm of width is covered partly by dielectric (thin rubber) with 11 mm of width, while the geometry of both metal electrodes is same to Type I. In the case of Type I, maximum concentration of about 100 ppm and maximum yield of 70 g/kWh were obtained at input power of 0.3 W. On the other hands, in the case of Type II, 800 ppm and 100 g/kWh were obtained at input power of 1.5 W. It was found ...

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It is shown that calculation of the anomalous expectation values for the massless Gross-Neveu model in the Hartree-Fock approximation indicates the presence of an ordinary chiral phase transition if the coupling constant has the normal sign (g > 0) and of a different transition of the superconductivity type if g < 0.

Energy Technology Data Exchange (ETDEWEB)

Neutron transmutation doping(NTD) for producing ntype silicon semiconductor is based on the conversion of the Si-30 isotope into phosphorus atom by neutron absorption reaction. By using this method, silicon semiconductors with extremely uniform n-type dopant distributions can be produced, and this is the dominant advantage of NTD compared with the conventional chemical doping. HANARO has two vertical holes for NTD, and the commercial NTD service for 5 and 6 inch silicon ingots has been going on at the NTD2 hole. Generally, NTD method is applied to the initially n-type silicon material. But, an initially p-type silicon material can also be used for the production of uniformly doped n-type silicon by using NTD method. Therefore, in this work, we investigated the relationship between the irradiation neutron fluence and the final resistivity of the initially p-type silicon material. ...

UK PubMed Central (United Kingdom)

Genes of the S100 fused-type protein (SFTP) family are clustered within the epidermal differentiation complex and encode essential components that maintain epithelial homeostasis and barrier functions....Full Text Available

CERN Document Server

We show how one can associate to a given class of finite type G-structures a classifying Lie algebroid. The corresponding Lie groupoid gives models for the different geometries that one can find in the class, and encodes also the different types of symmetry groups.

UK PubMed Central (United Kingdom)

DNA from the peripheral blood mononuclear cells of 17 different individuals infected with human T-cell lymphoma/leukemia virus type II (HTLV-II) was successfully amplified by the polymerase chain reaction...Full Text Available

UK PubMed Central (United Kingdom)

Two infants were seen with severe ascites detected before birth, a previously unreported presentation of Niemann-Pick disease type C. In the second infant no diagnostic storage cells were present in...Full Text Available

UK PubMed Central (United Kingdom)

Neurofibromatosis type 1 (NF-1) and tuberous sclerosis complex (TSC) are two familial syndromes known as phakomatoses that may be associated with endocrine tumors. These hereditary cutaneous...Full Text Available

UK PubMed Central (United Kingdom)

The mechanical properties of laminated window profiles manufactured using two types of adhesives were determined. The objective of this study is to evaluate the effects of heat treatment on some mechanical...Full Text Available

UK PubMed Central (United Kingdom)

Objective:To estimate the prevalence of insulin resistant syndrome (IRS) among newly diagnosed patients with type 2 diabetes and to test their validity against two indices...Full Text Available

UK PubMed Central (United Kingdom)

Although collagen-containing implants are widely used in various surgical applications, there has been relatively little attention paid to the possibility that this type of biomaterial may undergo pathologic...Full Text Available

UK PubMed Central (United Kingdom)

ObjectiveTo address mechanisms that control the activity of human peptidyl arginine deiminase type 4 (PAD-4).MethodsFull Text Available

UK PubMed Central (United Kingdom)

Chronic arsenic exposure has been suggested to contribute to diabetes development. We performed a systematic review of the experimental and epidemiologic evidence on the association of arsenic and type...Full Text Available

UK PubMed Central (United Kingdom)

A sensitive and specific detection method was developed for Xanthomonas hyacinthi; this method was based on amplification of a subsequence of the type IV fimbrial-subunit gene fimA...Full Text Available

UK PubMed Central (United Kingdom)

Anaerobic reactions of Rhus vernicifera laccase and its type-2 copper-depleted derivatives with hexacyanoferrate(II) were investigated by absorption and e.s.r. spectroscopy. When native laccase was...Full Text Available

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A method is presented to derive the absolute dimensions of early-type detached binaries by combining the observed parameters with results of evolutionary computations. The method is used to obtain the absolute dimensions of nine close binaries. We find that most systems have an initial masss ratio near 1.

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This report covers the test methods and equipment for testing aircraft armor both hard and soft. The hard armor are the typical ceramic type while the soft armor are various types of layered composite materials. 10 figs. (JEF)

UK PubMed Central (United Kingdom)

Recent studies have indicated that the DNA replication machinery is coupled to silencing of mating-type loci in the budding yeast Saccharomyces cerevisiae, and a similar silencing mechanism...Full Text Available

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The wave function of the Bianchi type-IX universe with small anisotropy is calculated using the Hartle-Hawking prescription.

Science.gov (United States)

is 10 seconds for P-type silicon material,. TO ,. In ordkr to determine the effects of unbalanced ionization between the two ...

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No abstract prepared.

Science.gov (United States)

... they assisted in the 2000 attack on the USS Cole? ... List the types of targets that ETA has attacked. ... was at least partially responsible for the attack. ...

International Nuclear Information System (INIS)

Recent work on N=2 supersymmetric Bianchi type IX cosmologies coupled to a scalar field is extended to a general treatment of homogeneous quantum cosmologies with explicitly solvable momentum constraints, i.e., Bianchi types I, II, VII, VIII in addition to the Bianchi type IX, and special cases, namely, the Freidmann universes, the Kantowski-Sachs space, and Taub-NUT space. In addition to the earlier explicit solution of the Wheeler-DeWitt equation for Bianchi type IX, describing a virtual wormhole fluctuation, an additional explicit solution is given and identified with the ''no-boundary state.''.

International Science & Technology Center (ISTC)

Safe Transference of Spent Fuel Assemblies from Near-Reactor Storage Pools to Long-term "Dry" Storage

Science.gov (United States)

PMID:21343599

International Nuclear Information System (INIS)

... brakes lmfbr type reactors breeder reactors epithermal reactors fast reactors