UK PubMed Central (United Kingdom)

Replication of plus-strand RNA viruses depends on host factors that are recruited into viral replicase complexes. Previous studies showed that eukaryotic translation elongation factor (eEF1A) is one...Full Text Available

UK PubMed Central (United Kingdom)

Polypeptides exiting the ribosome must fold and assemble in the crowded environment of the cell. Chaperones and other protein homeostasis factors interact with newly translated polypeptides to facilitate...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

The objectives of this paper are to: quickly outline the extent of the care gap in osteoporosis; define T-2 (knowledge) translation and its relationship to quality improvement; discuss the barriers to best practice in osteoporosis care after a fracture; convey the importance of rigor in design and evaluation of translational interventions by drawing upon examples from the broader literature; describe in some detail a series of post-fracture intervention trials conducted in Alberta, Canada; and make some conclusions specifically about osteoporosis interventions and more generally about T-2 translational research.

UK PubMed Central (United Kingdom)

BackgroundUnderstanding the mechanisms that control rates of disease progression in humans and other species is an important area of research relevant to epidemiology and to translating...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundMany interventions found to be effective in health services research studies fail to translate into meaningful patient care outcomes across multiple contexts. Health services...Full Text Available

UK PubMed Central (United Kingdom)

The objective of this research was to determine the role of acidic ribosomal protein (ARP) phosphorylation in translation. Ribosomes (Rbs) from germinated maize (Zea mays L.) axes had...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Despite the many advances in scientific research over the last several decades, cutting edge technologies and therapeutics often take many years to find their way into widespread use. The dissemination and uptake of best practices into clinical care is sometimes a neglected component of research that is essential to improve the population?s health. Type 2 translational research, sometimes called ?Proof in Practice Research,? seeks to maximize the yield of what has been learned from the bench and from carefully controlled clinical trials and to extend those benefits to a larger population. One aspect of type 2 translational research, sometimes called evidence implementation or implementation science, applies what has been learned about clinical medicine to achieve best practices across prov...

UK PubMed Central (United Kingdom)

BackgroundGenomics has substantially changed our approach to cancer research. Gene expression profiling, for example, has been utilized to delineate subtypes of cancer, and facilitated...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Delivering the promise of personalised medicine is the challenge that the current generation of scientists face. The variations in human physiology and disease are considerable, and designing appropriate strategies to deliver what has been promised will require access to tissue from a large number of volunteers. The NHS provides an ideal infrastructure for sample acquisition, but requires two things to make this available?public consent and support for extra manpower and administration. There is a disconnection between the NHS and tissue based research that needs to be addressed on a number of levels to provide a translational platform. This should enable the path to be beaten to provide the ideal tailored treatment for future patients; one that preserves quality of life by curing the dise...

Wastenet

... Removal of this layer facilitates the unreeling of cocoons into long strands of silk comparable to those derived from the domesticated mulberry silkworm (Bombyx mori, B. mori). The research was funded in part by the SABIP ('Silks as biomimetic ideals for polymers) project, which has clinched a European Research Council (ERC) grant worth almost EUR 2.3 million under the EU's Seventh Framework Programme (FP7). Presented in the journal Biomacromolecules, the findings could lead to the development of new silk industries in ...

British Library Electronic Table of Contents (United Kingdom)

Translating experimental findings into clinically effective therapies is one of the major bottlenecks of modern medicine. As this has been particularly true for cerebrovascular research, attention has turned to the quality and validity of experimental cerebrovascular studies. We set out to assess the study design, statistical analyses, and reporting of cerebrovascular research. We assessed all original articles published in the Journal of Cerebral Blood Flow and Metabolism during the year 2008 against a checklist designed to capture the key attributes relating to study design, statistical analyses, and reporting. A total of 156 original publications were included (animal, in vitro, human). Few studies reported a primary research hypothesis, statement of purpose, or measures to safeguard in...

Energy Technology Data Exchange (ETDEWEB)

Norad commissioned Econ Poeyry to map teaching and research activities and capacity related to clean energy in selected Ethiopian universities. The mapping identified challenges and opportunities with the aim of facilitating future intervention by the Ethiopian Government and donors to help improve the energy sector development of the country. The report covered the government-owned universities of Bahir Dar, Mekelle, Jimma, Arba Minch and Addis Ababa. The mapping was based on a questionnaire and on interviews at each university. (Author)

British Library Electronic Table of Contents (United Kingdom)

ABSTRACT Introduction. Significant progress has been made in the understanding of physiological and pharmacological mechanisms of human sexual functioning through preclinical research in animal models. Aim. To provide an evidence-based documentation of the experimental models evaluating male and female sexual function for useful clinical translation. Methods. Consensus discussion over the past 18 months leading to summarized views of seven experts from six countries. Main Outcome Measure. Report was based on the critical analysis of scientific information available in literature and subcommittee presentations, discussions, and exchanges of ideas and feedback. Results. Fundamental research in animal models has led to considerable understanding of the physiological mechanisms underlying desi...

British Library Electronic Table of Contents (United Kingdom)

Research and bioethical policies are increasingly seen to facilitate, rather than to impede, scientific progress. Bioethical structures, nonetheless, often fail to account for or to shape the specific social surrounds in which scientific research is conducted. In Taiwan, a perceived shortage in human biological donations threatens to hamper stem cell research progress. This paper considers the stalled national biobank project and the lack of a reliable embryo supply for stem cell research, and suggests that one must look beyond regulatory structures in seeking explanations for such shortages. Specific aspects of Taiwan's democratization and social changes combine with problematic relations between patients and physicians to shape the terrain upon which human biologicals are given or withhe...

KoreaScience (Korea)

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British Library Electronic Table of Contents (United Kingdom)

Over the decades, basic research in life sciences has profited greatly from the study of the small unicellular fungal species Saccharomyces cerevisiae. This yeast turned out to be key for the identification and understanding of molecular mechanisms that underlay the basic functions of all eukaryotic cells. These include, but are not limited to, the regulatory mechanisms behind cellular reproduction (cell cycle control), cellular morphogenesis (cell polarity, cytoskeleton and membrane trafficking) and the management of cellular information (chromosome biology, transcription and translation). Rapid access to genomic information of many yeast species, combined with bioinformatics analyses, provide information on the evolutionary history of yeasts and the molecular ancestry of their constituen...

Energy Technology Data Exchange (ETDEWEB)

The Ohio State University Research Reactor (OSURR) is licensed to operate at a maximum power level of 500 kW. A pool-type reactor using flat-plate, low enriched fuel elements, the OSURR provides several experimental facilities including two 6-inch i.d. beam ports, a graphite thermal column, several graphite-isotope-irradiation elements, a pneumatic transfer system (Rabbit), various dry tubes, and a Central Irradiation Facility (CIF). The core arrangement and accessibility facilitates research programs involving material activation or core parameter studies. The OSURR control room is large enough to accommodate laboratory groups which can use control instrumentation for monitoring of experiments. The control instrumentation is relatively simple, without a large amount of duplication. This facilitates opportunities for hands-on experience in reactor operation by nuclear engineering students making reactor ...

Energy Technology Data Exchange (ETDEWEB)

Guidelines and ground rules followed in the development of requirements for the SPS are presented. Development planning objectives are specified in each of these areas, and evolutionary SPS program scenarios are described for the various concepts studied during the past one year contract. Program descriptions are presented as planning packages of technical tasks, and schedule phasing. Each package identifies the ground based technology effort that will facilitate SPS definitions, designs, development, and operations.

Energy Technology Data Exchange (ETDEWEB)

Financing space solar power generation programmes has several inherent difficulties. Such large-scale projects are usually easily defined with an expected economic return, construction time, useful service life and defined management structure. As yet, solar power satellites for power generation possess none of these as the idea exists conceptually and the technology still needs to be developed. Methods for overcoming these uncertainties and securing financial backing are described. Venture capital could finance a research/marketing firm. US Government support through a cost plus short-term monopoly to facilitate private debt financing could provide an answer. (UK)

Energy Technology Data Exchange (ETDEWEB)

Integration of positron emission tomography (PET) and magnetic resonance (MR) has become a topic of increasing interest to the imaging community over the past two years. In this text, the authors attempt to distinguish facts from fiction concerning such integrated systems. Analysis of existing information of combined imaging on existing brain PET/MR systems and imaging experience with PET-computed tomography (CT) is reviewed. Various types of system integration of PET and MR are discussed with completely independent systems on one hand and completely integrated systems with the possibility of simultaneous data acquisition on the other hand. Furthermore, it is discussed, what simultaneous data acquisition with nuclear imaging systems combined with MR or CT really means, as technical simultaneity may not be relevant in light of the pharmacokinetics of the nuclear tracers used. The authors conclude that combining PET/MR is an interesting research endeavor with ...

UK PubMed Central (United Kingdom)

We have studied the functions of the intracellular RNAs of mouse mammary tumor virus (MMTV) by purification and translation in vitro. Two major size classes of MMTV RNA, 35S and 24S RNA, were isolated...Full Text Available

UK PubMed Central (United Kingdom)

SummarySpatial control of gene expression, at the level of both transcription and translation, is critical for cellular differentiation [1-Full Text Available

Science.gov (United States)

... unlimited. It may be released to the Clearinghouse. DePartment of Comereforsae o te enga Page 2. EDITED TRANSLATION A ...

Science.gov (United States)

ICU telemedicine uses audiovisual conferencing technology to provide critical care from a remote location. Research is needed to best define the optimal use of ICU telemedicine, but efforts are hindered by methodological challenges and the lack of an organized delivery approach. We convened an interdisciplinary working group to develop a research agenda in ICU telemedicine, addressing both methodological and knowledge gaps in the field. To best inform clinical decision-making and health policy, future research should be organized around a conceptual framework that enables consistent descriptions of both the study setting and the telemedicine intervention. The framework should include standardized methods for assessing the preimplementation ICU environment and describing the telemedicine program. This framework will facilitate comparisons across studies and improve generalizability by permitting ...

Energy Technology Data Exchange (ETDEWEB)

One important factor frustrating optimal management of Department of Energy (DOE)-complex wastes is the inability to use licensed and permitted facilities systematically. Achieving the goal of optimal use of DOE`s waste management facilities is politically problematic for two reasons. First, no locale wants to bear a disproportionate burden from DOE wastes. Second, the burden imposed by additional wastes transported from one site to another is difficult to characterize. To develop a viable framework for equitably distributing these burdens while achieving efficient use of all DOE waste management facilities, several implementation and equity issues must be addressed and resolved. This paper discusses stakeholder and equity issues and proposes a framework for joint research and action that could facilitate equity negotiations among stakeholder and move toward a more optimal use of DOE`s waste management capabilities.

Energy Technology Data Exchange (ETDEWEB)

A novel adaptive stabilizer, called an Adaptive Governor Power System Stabilizer (AGPSS), which operated on the governor turbine system, was described. There has been extensive research on adaptive excitation control of generators in power systems with the goal of achieving better dynamic performance. AGPSS tracks the frequency and damping of oscillations in a power system, and adjusts to ensure that there is always sufficient damping in the system. There is no interaction between stabilizers on different generating units, and each one acts independently, consuming oscillation energy locally. These stabilizers are easy to design and this facilitates their use in multimachine systems. Results obtained by nonlinear simulation of a single-machine and a three-machine power system were discussed, illustrating the effectiveness of the stabilizers in supplying damping and improving stability. It was pointed out that the operation of AGPSS does not ...

Environmental Research Database

Objectives1. The study of the automatic alignment of electrically charged optical fibres.~%~~%~2. The design and construction of a prototype system for assembly of the fibres.~%~~%~3. The fabrication of a proof-of-principle 4-by-4 fibre array.~%~~%~4. The test and characterisation of the prototype fibre bundle in terms of translational and angular positioning accuracy.~%~~%~5. A paper design of a full-scale automated system.~%~~%~6. Enable commercial exploitation.~%~DescriptionThis multidisciplinary programme aims to investigate and develop an 'adventurous' process for manufacturing 2-D optical fibre arrays, with at least an order of magnitude improvement in the positional and angular tolerances of the mono-mode fibres compared to conventional techniques. Manufacturable, dense 2-D optical fibre arrays are essential for a wide variety of telecoms, computing and instrumentation ...

Energy Technology Data Exchange (ETDEWEB)

The goal of assembly sequencing is to plan a feasible series of operations to construct a product from its individual parts. Previous research has thoroughly investigated assembly sequencing under the assumption that parts have nominal geometry. This paper considers the case where parts have toleranced geometry. Its main contribution is an efficient procedure that decides if a product admits an assembly sequence with infinite translations that is feasible for all possible instances of the components within the specified tolerances. If the product admits one such sequence, the procedure can also generate it. For the cases where there exists no such assembly sequence, another procedure is proposed which generates assembly sequences that are feasible only for some values of the toleranced dimensions. If this procedure produces no such sequence, then no instance of the product is assemblable. Finally, this paper analyzes the relation between ...

DEFF Research Database (Denmark)

Udgivelsesdato: October 2004

Energy Technology Data Exchange (ETDEWEB)

A model for the structural relaxation of grain boundaries (GBs) in nanostructured materials (NSMs) by diffusion-accommodated rigid body translations along GBs is proposed. The model is based on the results of recent computer simulations that have demonstrated that the GBs in NSMs retain a high-energy structure with random translational states due to severe geometrical constraints applied from neighboring grains (J. Appl. Phys. 78 (1995) 847; Scripta Metall. Mater. 33 (1995) 1245). The shear stresses within a GB caused by non-optimized rigid-body translations (RBTs) can be accommodated by diffusive flow of atoms along a GB. This mechanism is particularly important for low-angle and vicinal GBs, the energy of which noticeably depends on the rigid body translations. At moderate and high temperatures the model yields relaxation times that are very short and therefore GBs in NSMs can attain an equilibrium ...

Energy Technology Data Exchange (ETDEWEB)

In 1986, the National Research Council, through its Energy Engineering Board, formed the Committee on Geothermal Energy Technology. The committee's study addressed major issues in geothermal energy technology, made recommendations for research and development, and considered cooperative arrangements among government, industry, and universities to facilitate RandD under current severe budget constraints. The report addresses four types of geothermal energy: hydrothermal, geopressured, hot dry rock, and magma systems. Hydrothermal systems are the only type that are now economically competitive commercially. Further technology development by the Department of Energy could make the uneconomical hydrothermal resources commercially attractive to the industry. The economics are more uncertain for the longer-term technologies for extracting energy from geopressured, hot dry rock, and magma systems. For some sites, the cost ...

Environmental Research Database

Objectives1. To identify with older people the problems which they encounter in finding their way about public building/spaces.~%~2. To produce ideas, in consultation with older people, for an information/navigation aid that might facilitate their use and enjoyment of public buildings/spaces, notably hospitals, large shops, railway stations, airports.~%~3. To develop an emulation model of the information/navigation aid~%~4. To monitor use of the model by older people~%~5. To identify further research~%~6. [continued...]DescriptionThe growth in the number of older people offers scope for the development of customised information/navigation aids to help them to find their way around complex public spaces. New technology however is unlikely to be taken up by older people unless it is acceptable to them. The research will involve engineers in designing, testing and modifying a model of such an aid in conjunction with a sample ...

Science.gov (United States)

curves are also directly translatable to metal-matrix composites. ..... 4~f4'4 ..... result of learning curve. The most important reduction in cost as a ...

UK PubMed Central (United Kingdom)

The central features of the mechanical cycle that drives the contraction of muscle are two translational steps: the working stroke, whereby an attached myosin crossbridge moves relative to the actin...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

This paper analyses the role of the translator in the representation of alterity and the construction of national identity, with reference to the work of a nineteenth-century Egyptian translator, essayist and educationalist, Rif?'a R?fi' al-TahT?wi (1801-1874). The essay takhliS al-ibriz fi talkhiS b?ris ("The Extraction of Gold in the Summarizing of Paris") includes numerous examples of constructive translation and representation, which familiarised and legitimised the "other" through the identification of parallels, common values and experience. Al-TahT?wi negotiated between conflicting discourses of modernism and traditionalism, and it is argued that the issues of representation raised in his work are of particular relevance to contemporary concerns in the ...

Science.gov (United States)

... AEC - Atomic Energy Commission (see CFSTI) AERE Harwell Lib The Librarian AERE, Ministry of Supply Harwell, Didcot, Birks England AF ...

Science.gov (United States)

A significant challenge in proteomics biomarker research is to identify the changes that are of highest diagnostic interest, among the many unspecific aberrations associated with disease burden and inflammation. In the present study liver tissue specimens (n=18) from six experimental stages were collected from the resistant hepatocyte (RH) rat model of liver cancer and analyzed by 2D DIGE. The study included triplicates of regenerating liver, control "sham-operated" liver, three distinct premalignant stages and hepatomas. Out of 81 identified proteins two-thirds were differentially abundant in rat hepatomas compared to control rat liver and, secondly, the majority of proteins were also changed in precursor stages. This underscores the importance of adequate control samples in explorative cancer biomarker research. We confirm several proteomic changes previously identified in human hepatocellular carcinoma (HCC) and we identify novel candidate ...

Science.gov (United States)

The non-invasiveness of autofluorescence technology may reduce sampling error and time delay for histopathology diagnosis. We establish biophotonic methods and guidelines to visualize and interpret early epithelial tissue changes that signify disease. Flexible and rigid fiber endomicroscopy instrumentation design parameters feasible for translation towards clinical use are in development.

International Nuclear Information System (INIS)

Full text: Founded in 1964, Ankara Nuclear Research and Training Center (ANRTC) conducts and facilitates the scientific activities including training (summer practice, MSc and Ph D studies in physics and chemistry, IAEA fellowship programs etc.), research and other studies in nuclear and related fields. As it's a part of main duties, ANRTC has analysis on the variety of samples, and radiation protection services commercially, for radiation workers in state, public and private sectors. Research, development and application projects implemented in this Center have mostly been supported by State Planning Organization (SPO) and Turkish Atomic Energy Authority (TAEA). In addition to the projects there are on going collaborative studies with some national Universities and International Atomic Energy Agency. The main activities carried out in ANRTC can be summarized as: studies on experimental nuclear physics, ...

Wastenet

governance through land use planning and mechanisms to deal with informal urban settlements in a manner that will facilitate improvements in

Energy Technology Data Exchange (ETDEWEB)

The production of oil by retorting shale and other hydrocarbonaceous and lignocellulosic solid materials is facilitated by retorting in the presence of steam and acetic acid.

Science.gov (United States)

The thermal dissolver, the main reactor of the SRC unit, has suffered a recurring problem. Specifically, it has been observed that whenever the reactor vessel is cooled to below 400/sup 0/F, its bottom head gasket leaks. An analysis of the thermal stress induced in the gasket, owing to transients across the bottom head flange, was sought. The analysis was facilitated by judiciously dividing a symmetric section of the reactor into 79 differential elements. Heat balances have been developed around each element. A numerical technique, the backward finite-difference approach, was employed to obtain the thermal behavior across the bottom head flange as a function of reactor heat-up time. The analysis performed affords an explanation for the failure of the gasket. Based on results of this work, recommendations have been suggested to provide the gasket and bolt stress requirements that are necessary to avoid leaks due to temperature changes.

Energy Technology Data Exchange (ETDEWEB)

Research commenced in FY 97 to determine the suitability of superplasticized cement-sand grouts for backfilling vertical boreholes used with geothermal heat pump (GHP) systems. The overall objectives were to develop, evaluate and demonstrate cementitious grouts that could reduce the required bore length and improve the performance of GHPs. This report summarizes the accomplishments in FY 98. The developed thermally conductive grout consists of cement, water, a particular grade of silica sand, superplasticizer and a small amount of bentonite. While the primary function of the grout is to facilitate heat transfer between the U-loop and surrounding formation, it is also essential that the grout act as an effective borehole sealant. Two types of permeability (hydraulic conductivity) tests was conducted to evaluate the sealing performance of the cement-sand grout. Additional properties of the proposed grout that were investigated include bleeding, ...

International Nuclear Information System (INIS)

Security is an essential element of information technology (IT) infrastructure and applications. Concerns about security of networks and information systems have been growing along with the rapid increase in the number of network users and the value of their transactions. The hasty security threats have driven the development of security products known as Intrusion Detection Systems (IDS) and Intrusion Prevention Systems (IPS) to detect and protect the network, server and desktop infrastructure ahead of the threat. Authentication and signing techniques are used to prevent integrity threats. Users, devices, and applications should always be authenticated and authorized before they are allowed to access networking resources. Though a lot of information is available on the internet about IDS and IPS but it all is spread on so many sites and one has to spend a considerable part of his precious time to search it. In this regard a thorough survey has been conducted to ...

Energy Technology Data Exchange (ETDEWEB)

Nuclear physics accelerators are powered by microwaves which must travel in waveguides between room-temperature sources and the cryogenic accelerator structures. The ohmic heat load from the microwaves is affected by the temperature-dependent surface resistance and in turn affects the cryogenic thermal conduction problem. Integrated EM & thermal analysis of this difficult non-linear problem is now possible with the VORPAL finite-difference time-domain simulation tool. We highlight thermal benchmarking work with a complex HOM feed-through geometry, done in collaboration with researchers at the Thomas Jefferson National Accelerator Laboratory, and discuss upcoming design studies with this emerging tool. This work is part of an effort to generalize the VORPAL framework to include generalized PDE capabilities, for wider multi-physics capabilities in the accelerator, vacuum electronics, plasma processing and fusion R&D fields, and we will also discuss user ...

International Nuclear Information System (INIS)

Until recent years, those involved in the design, operation and regulation of nuclear power systems devoted more resources to forward movement than to the back end of the fuel cycle. Now, though, concerted thought and international cooperation have been devoted to the question of nuclear waste management. The expert consensus is that sufficient knowledge exists to make e.g. disposal decisions with an acceptable level of confidence. In the first phases of research, decision processes were adapted to the tasks at hand. However, at some point in each nuclearized country, there came a time when waste management implied finding repository sites. At that time management abruptly entered the social sphere - where unfortunate experience has shown time and time again that classical decision processes are not adapted to facilitating societal acceptance of management solutions. This paper recounts the various management frameworks that have been tested in ...

Energy Technology Data Exchange (ETDEWEB)

Oxide catalysis plays a central role in hydrocarbon processing and improvements in catalytic activity or selectivity are of great technological importance because these improvements will translate directly into more efficient utilization of hydrocarbon supplies and lower energy consumption in separation processes. An understanding of the relationships between surface structure and catalytic properties is needed to describe and improve oxide catalysts. Our approach has been to prepare supported oxides that have a specific structure and oxidation state and then employ these structures in reaction studies. Our current research program is focused on studying the fundamental relationships between structure and reactivity for two important reactions that are present in many oxide-catalyzed processes, partial oxidation and carbon-carbon bond formation. Oxide catalysis can be a complex process with both metal cation and oxygen anions participating in ...

Energy Technology Data Exchange (ETDEWEB)

Fine ceramics center (JFCC) succeeded in the higher precision of thermal diffusivity measurement by the laser flash. This results are part of 'the research on thermophysical property measurement technique and standard substance of the functional material' by the intelligent establishing of a base promotion system of Science and Technology Agency. Cooperative research. thermal diffusivity with Natl. Res. Lab. of Metrology is one of the representative thermophysical property. The speed in which a heat transmits of the material is shown, and it is indispensable to the design of the high-temperature member subject. JFCC heralds the world as a standard substance for the thermal diffusivity measurement; 'TD-AL' using the alumina material is developed and is supplied in the spring in last year. Laser flash which uses laser beam for the heat source is general for the measurement. However, there was grinding undercut ...

UK PubMed Central (United Kingdom)

Memory consolidation requires transcription and translation of new protein. Arc, an effector immediate early gene, and zif268, a regulatory transcription factor, have been implicated in synaptic plasticity...Full Text Available

UK PubMed Central (United Kingdom)

Robert van Gulik was a respected Dutch sinologist and author who first translated a collection of traditional Chinese detective stories into English and then created additional fictional stories based...Full Text Available

UK PubMed Central (United Kingdom)

Fresh blood has many potential advantages over older blood, but there is no evidence that these properties translate into clinical benefit for intensive care patients. The observational multicenter...Full Text Available

UK PubMed Central (United Kingdom)

In vitro translation systems were prepared with supernatant factors from wheat germ and 80S ribosomes from wheat germ, barley embryos, watermelon cotyledons, pea cotyledons, and castor...Full Text Available

UK PubMed Central (United Kingdom)

MicroRNAs (miRNAs) are endogenously encoded small noncoding RNAs, derived by processing of short RNA hairpins, that can inhibit the translation of mRNAs bearing partially complementary target sequences....Full Text Available

UK PubMed Central (United Kingdom)

BackgroundHIV-1 reverse transcriptase (RT) is a heterodimer composed of p66 and p51 subunits and is responsible for reverse transcription of the viral RNA genome into DNA. RT can...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Experience has shown that a list of tips provides designers and engineers with an effective guide in their areas of duties and concern. This list contains new and rare information on heat exchangers and heat recovery systems. The information presented can be used effectively with personal computers and pocket calculators and also conveniently translated into computer programs and nomographs.

UK PubMed Central (United Kingdom)

Rapid place encoding by hippocampal neurons, as reflected by place-related firing, has been intensely studied, whereas the substrates that translate hippocampal place codes into behavior have received...Full Text Available

UK PubMed Central (United Kingdom)

We cloned and sequenced structural gene choM, which encodes an insecticidally active cholesterol oxidase in Streptomyces sp. strain A19249. The primary translation product was predicted to be a 547-amino-acid...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundHistone post-translational modifications are critical for gene expression and cell viability. A broad spectrum of histone lysine residues have been identified in yeast...Full Text Available

UK PubMed Central (United Kingdom)

In many eukaryotic mRNAs one or more short ‘upstream’ open reading frames, uORFs, precede the initiator of the main coding sequence. Upstream ORFs are functionally diverse as illustrated...Full Text Available

Science.gov (United States)

isotherme, dans un courant d'azote ou sous vide entretenu. I t. Comptes Rendus Scientific Academy, Paris, Vol. 265 pyrolyse du carbonate de calcium, ...

Energy Technology Data Exchange (ETDEWEB)

This patent describes an automatic loading roller for transmitting torque in traction drive devices in manipulator arm joints includes a two-part camming device having a first cam portion rotatable in place on a shaft by an input torque and a second cam portion coaxially rotatable and translatable having a rotating drive surface thereon for engaging the driven surface of an output roller with a resultant force proportional to the torque transmitted. Complementary helical grooves on the respective cam portions interconnected through ball bearings interacting with those grooves effect the rotation and translation of the second cam portion in response to rotation of the first.

International Nuclear Information System (INIS)

The French radioactive waste management act of December 30, 1991, included two key provisions. It initiated a major research program with three areas of investigation concerning high-level long-lived radioactive waste management routes, and called for the Government to submit a legislative proposal to Parliament within 15 years (by 2006) specifying the policy guidelines adopted. Considering the sensitive nature of the subject, the questions surrounding the issue of radioactive waste, and the social, economic and environmental concerns for present and future generations, the Government has inaugurated, in 2005, a nationwide public debate on these issues between the submittal of the research reports and the parliamentary discussion of the proposed law. In this context, the CEA has decided to concentrate at Marcoule the expertise and experience acquired in the area of radioactive waste management and to make it available to stakeholders and to the ...

Energy Technology Data Exchange (ETDEWEB)

This bibliography contains abstracts relating to various aspects of ALARA program implementation and dose reduction activities, with a focus on DOE facilities. Abstracts included in this bibliography were selected from proceedings of technical meetings, journals, research reports, searches of the DOE Energy, Science and Technology Database (in general, the citation and abstract information is presented as obtained from this database), and reprints of published articles provided by the authors. Facility types and activities covered in the scope of this report include: radioactive waste, uranium enrichment, fuel fabrication, spent fuel storage and reprocessing, facility decommissioning, hot laboratories, tritium production, research, test and production reactors, weapons fabrication and testing, fusion, uranium and plutonium processing, radiography, and aocelerators. Information on improved shielding design, decontamination, containments, ...

UK PubMed Central (United Kingdom)

BackgroundIncrease in the incidence of hyperuricemia associated with gout as well as hypertension, renal diseases and cardiovascular diseases has been a public health concern. We...Full Text Available

UK PubMed Central (United Kingdom)

The receptor-associated protein (RAP) is a molecular chaperone that binds tightly to certain newly synthesized LDL receptor family members in the endoplasmic reticulum (ER) and facilitates their delivery...Full Text Available

UK PubMed Central (United Kingdom)

Background: The nail gun is a commonly utilized tool in carpentry and construction. When used properly with appropriate safety precautions, it can facilitate production and boost efficiency;...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Summary 1.-Plant-plant interactions fluctuate between competition and facilitation depending upon ecological conditions and species traits. Facilitative interactions are expected to increase in frequency via associational defences with increasing consumer pressure. The ability of species to cope with competition and/or ecological stressors may alter the outcome of plant-plant interactions. 2.-We conducted a transplant experiment to determine if native and non-native grasses and forbs respond similarly to interactions with Juncus effusus L., an unpalatable benefactor species, along a grazing intensity gradient in two contrasting pasture types: intensively managed and semi-natural. We expected competitive taller, erect species (grasses) and non-natives to obtain stronger facilitative effects...

Science.gov (United States)

This paper makes a case for "good politics for good education", with special reference to Nigeria. It surveys the impact of good and bad politics on the attainment of Meaningful Access to education with special focus on Nigeria's Universal Basic Education (UBE) programme. Good politics is to be likened to what the French call "la politique au sense noble du terme" (politics in the noble sense of the term--or statesmanship) while bad politics is to be likened to a "politique politicienne" (mere divisive politicking, or politics in its raw form). Politics in its raw form is concerned with seeking power for self-aggrandisement while politics in its noble form is concerned with seeking power for public good. In situations where good politics prevails, educational policies, programmes and delivery processes tend to produce the desirable outcome of "children passing through school and the school also passing through them". By combining the seven exclusion zones used in the work of CREATE ...

Energy Technology Data Exchange (ETDEWEB)

The Plant Life Assessment Network (PLAN) is a Brite Euram Type II Thematic Network, initiated by the European Commission to facilitate structured co-operation between all cost shared action projects already funded by the Commission which fall under this common technical theme. The projects involved address a multiplicity of problems associated with plant life assessment and are drawn from Brite-Euram, Standards, Measurement and Testing, Nuclear Fission Safety and Esprit EC programmes. The main aim of the Network is to initiate, maintain and monitor a fruitful co-operation process between completed, ongoing and future EC R and D projects, thereby promoting improved cross fertilization and enhanced industrial exploitation of R and D results. As the project is in its infancy, this presentation covers the background to the initiative in some detail. In particular two key aspects are highlighted, namely, the requirement of the EC to launch such a network in the area of ...

Energy Technology Data Exchange (ETDEWEB)

The minimization of the environmental footprint is the underlying principle of companies involved in sustainable development. At the same time, those companies seek to contribute to the economic and social development of the communities in which they have a presence. The evidence linking sustainable development and value creation are examined in this report targeted to the investment community, which is part of an overall leadership initiative undertaken by the Conference Board of Canada. The benchmarks of companies committed to sustainable development have, on the whole, been matched or exceeded, as shown by recent evidence based on the performance of seven prominent funds and indices managed in Canada, the United States, and western Europe. They are: the Domini Social Equity Fund (American focus), the EcoValue 21{sup TM} (American focus), the Dow Jones Sustainability Group Index (international focus), Storebrand Scudder Environmental Value Fund (European focus), the Jantzi Social ...

International Nuclear Information System (INIS)

Exploratory experiments of laser welding cast Ni-based superalloy K418 turbo disk and alloy steel 42CrMo shaft were conducted. Microstructure of the welded seam was characterized by optical microscopy (OM), scanning electron microscopy (SEM), X-ray diffraction (XRD), energy-dispersive spectrometer (EDS). Mechanical properties of the welded seam were evaluated by microhardness and tensile strength testing. The corresponding mechanisms were discussed in detail. Results showed that the laser-welded seam had non-equilibrium solidified microstructures consisting of FeCr_0_._2_9Ni_0_._1_6C_0_._0_6 austenite solid solution dendrites as the dominant and some fine and dispersed Ni_3Al #gamma#' phase and Laves particles as well as little amount of MC short stick or particle-like carbides distributed in the interdendritic regions. The average microhardness of the welded seam was relatively uniform and lower than that of the base metal due to partial dissolution and suppression of the ...

Energy Technology Data Exchange (ETDEWEB)

The NGDRS has facilitated 85% of cores, cuttings, and other data identified available for transfer to the public sector. Over 12 million linear feet of cores and cuttings, in addition to large numbers of paleontological samples and are now available for public use. To date, with industry contributions for program operations and data transfers, the NGDRS project has realized a 6.5 to 1 return on investment to Department of Energy funds. Large-scale transfers of seismic data have been evaluated, but based on the recommendation of the NGDRS steering committee, cores have been given priority because of the vast scale of the seismic data problem relative to the available funding. The rapidly changing industry conditions have required that the primary core and cuttings preservation strategy evolve as well. Additionally, the NGDRS clearinghouse is evaluating the viability of transferring seismic data covering the western shelf of the Florida Gulf Coast. AGI remains ...

Energy Technology Data Exchange (ETDEWEB)

Currently, over 30,000 mapped STSs and 27,000 mapped Unigenes (non-redundant, unigene sets of cDNA representing EST clusters) are available for human alone. A total of 44,000 Unigene cDNA clones have been supplied by Research Genetics. Unigenes, or cDNAs are excellent resource for map building for two reasons. Firstly, they exist in two alternative forms -- as both sequence information for PCR primer pairs, and cDNA clones -- thus making library screening by colony hybridization as well as pooled library PCR possible. The authors have developed an efficient and robust procedure to screen genomic libraries with large number of DNA probes. Secondly, the linkage and order of expressed sequences, or genes are highly conserved among human, mouse and other mammalian species. Therefore, mapping with cDNA markers rather than random anonymous STSs will greatly facilitate comparative, evolutionary studies as well as physical map building. They have ...

Energy Technology Data Exchange (ETDEWEB)

In this report is described the work effort performed to provide NETL with VE-Suite based Virtual Engineering software and enhanced equipment models to support NETL's Advanced Process Engineering Co-simulation (APECS) framework for advanced power generation systems. Enhancements to the software framework facilitated an important link between APECS and the virtual engineering capabilities provided by VE-Suite (e.g., equipment and process visualization, information assimilation). Model enhancements focused on improving predictions for the performance of entrained flow coal gasifiers and important auxiliary equipment (e.g., Air Separation Units) used in coal gasification systems. In addition, a Reduced Order Model generation tool and software to provide a coupling between APECS/AspenPlus and the GE GateCycle simulation system were developed. CAPE-Open model interfaces were employed where needed. The improved simulation capability is demonstrated on selected ...

CERN Document Server

SC Research Programme and Activities

Science.gov (United States)

A new protocol technology is just starting to emerge from the laboratory environment. Its stated purpose is to provide an additional means in which networks, and the services that reside on them, can be protected from adversarial compromise. This report has a two-fold objective. First is to provide the reader with an overview of this emerging Dynamic Defenses technology using Dynamic Network Address Translation (Dynat). This ''structure overview'' is concentrated in the body of the report, and describes the important attributes of the technology. The second objective is to provide a framework that can be used to help in the classification and assessment of the different types of dynamic defense technologies along with some related capabilities and limitations. This information is primarily contained in the appendices.

British Library Electronic Table of Contents (United Kingdom)

The behavior of proton transfer facilitated by a novel thiazole derivative, N-methyl-4-(4-phenoxyphenyl)thiazol-2-amine (MPPT), across the water/1,2-dichloroethane (1,2-DCE) interface was investigated electrochemically. The ionic partition diagram for MPPT was obtained from interpretation of the cyclic voltammograms. The apparent partition coefficient of MPPT was evaluated by the shaking-flask method under experimental conditions, while that for the protonated form of MPPT was calculated from its transfer potential obtained from the ionic partition diagram. It was suggested that the mechanism for transfer of MPPT across the water/1,2-DCE) interface depends on the pH of the aqueous phase. The parameters of the facilitated proton transfer across the water/1,2-DCE interface were evaluated as ...

International Nuclear Information System (INIS)

A possibility is considered or reducing the surface heterogeneity effect of an item being tested on the result of radiation flaw detection by means of signal delay of one of detectors in a two-channel radiometric flaw detector. The exposure of a translationally moving item has been studied as well as an external exposure of a rotating hollow item.

UK PubMed Central (United Kingdom)

In both type 1 and type 2 diabetes, pancreatic islet dysfunction results in part from cytokine-mediated inflammation. The ubiquitous eukaryotic translation initiation factor 5A (eIF5A), which is the...Full Text Available

UK PubMed Central (United Kingdom)

During protein synthesis, aminoacyl-tRNA (aa-tRNA) and release factors 1 and 2 (RF1 and RF2) have to bind at the catalytic center of the ribosome on the 50S subunit where they take part in peptide bond...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Achieving device independence for software applications is required for all but a small number of critical real time applications. Device independence is achieved by establishing protocols and building protocol interpreters for the specific devices. Data structures containing pointers to functions provide a flexible architecture for implementing protocol translation. 3 refs., 5 figs.

UK PubMed Central (United Kingdom)

MicroRNAs are short (∼22 nucleotides) noncoding RNAs that regulate the stability and translation of mRNA targets. A number of computational algorithms have been developed to help predict which...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe use of measurement tools is an essential part of good evidence-based practice; however, physiotherapists (PTs) are not always confident when selecting, administering,...Full Text Available

UK PubMed Central (United Kingdom)

Peripheral subunit binding domains (PSBDs) are integral parts of large multienzyme complexes involved in carbohydrate metabolism. PSBDs facilitate shuttling of prosthetic groups between different catalytic...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The demand for cogeneration plants is growing worldwide. For the combination of electricity generation and heat extraction in power stations facilitates an excellent fuel exploitation and makes the operator of the plant independent from external energy suppliers. (orig.)

UK PubMed Central (United Kingdom)

A general method is described to sequester peptides containing azides from complex peptide mixtures, aimed at facilitating mass spectrometric analysis to study different aspects of proteome...Full Text Available

UK PubMed Central (United Kingdom)

The widespread use of tobacco and alcohol among adolescents might be related to the ability of nicotine and ethanol to facilitate social interactions. To investigate the neurobehavioral mechanisms...Full Text Available

UK PubMed Central (United Kingdom)

The exposure of cells to several metal ions stabilizes HIF-1α protein. However, the molecular mechanisms are not completely understood. They may involve inhibition of hydroxylation by either...Full Text Available

UK PubMed Central (United Kingdom)

Lepidoptera, butterflies and moths, is the second largest animal order and includes numerous agricultural pests. To facilitate comparative genomics in Lepidoptera, we isolated BAC clones containing...Full Text Available

UK PubMed Central (United Kingdom)

This paper describes Image Engine, an object-oriented, microcomputer-based, multimedia database designed to facilitate the storage and retrieval of digitized biomedical still images, video, and text...Full Text Available

UK PubMed Central (United Kingdom)

RATIONALE AND OBJECTIVESNon-invasive longitudinal imaging of tumor vasculature could provide new insights into the development of solid tumors, facilitating efficient...Full Text Available

UK PubMed Central (United Kingdom)

The continuous addition of toluene as a solute of treated ballast water from oil tankers into a well-defined estuary facilitated the study of the dynamics of dissolved hydrocarbon metabolism in seawater....Full Text Available

UK PubMed Central (United Kingdom)

Objective: The paper describes and evaluates the use of Clinical Digital Libraries Project (CDLP) digital library collections in terms of their facilitation of timely clinical information...Full Text Available

UK PubMed Central (United Kingdom)

Medulloblastoma and neuroblastoma belong to a group of neoplasms designated as primitive neuroectodermal tumors (PNETs). Secreted Protein, Acidic and Rich in Cysteine (SPARC) is a matrix-associated...Full Text Available

Wastenet

...6 Resource type: documents MmIT: Multimedia Information and Technology Group Group aiming to facilitate communication between CILIP members interested in multimedia developments in the library and information science field. Visits to places of interest like museums and archives are frequently organised, and an email discussion list ...

UK PubMed Central (United Kingdom)

The aggregation substance (AS) of Enterococcus faecalis, encoded on sex pheromone plasmids, is a surface-bound glycoprotein that mediates aggregation between bacteria thereby facilitating...Full Text Available

UK PubMed Central (United Kingdom)

T-type calcium channels are responsible for generating low-threshold spikes that facilitate burst firing and neurotransmitter release in neurons. GnRH neurons exhibit burst firing, but the underlying...Full Text Available

Science.gov (United States)

... Exposure Treatment Research Program (NETRP); and a panel of doctors and researchers who will discuss Embryonic Stem Cell Research. ...

Science.gov (United States)

... centers in materials research. MRSECs address fundamental materials research topics of intellectual ... in materials research. II. PROGRAM DESCRIPTION MRSECs are supported by NSF to undertake materials ...

International Nuclear Information System (INIS)

Full text: Pink bollworm (PBW), Pectinophora gossypiella (Saunders), an introduced pest from Mexico, first occurred in United States cotton production in Texas in 1917. Unacceptable economic losses have occurred. The development of PBW sterile moth release technology, gossyplure sex pheromone behavioral control, cotton plant cultural control to reduce overwintered PBW populations, and the transfer of the insect toxin protein gene into cotton from Bacillus thuringiensis kurstaki (Berliner) have provided an effective integrated pest management (IPM) system with PBW eradication potential. Sterile insect release was considered a potential option for PBW population suppression in the early 1960s. Research on the isolated island of St. Croix, (US Virgin Islands) demonstrated its validity. Reductions of larval infestations in bolls following sterile moth releases began when ratios of released PBW sterile male to native male moths averaged 70:1 in gossyplurebaited traps. ...

CERN Document Server

n an early approach, we proposed a kinetic model with multiple translational temperature [K. Xu, H. Liu and J. Jiang, Phys. Fluids {\\bf 19}, 016101 (2007)], to simulate non-equilibrium flows. In this paper, instead of using three temperatures in $x-$, $y-$, and $z$-directions, we are going to further define the translational temperature as a second-order symmetric tensor. Based on a multiple stage BGK-type collision model and the Chapman-Enskog expansion, the corresponding macroscopic gas dynamics equations in three-dimensional space will be derived. The zeroth-order expansion gives the 10 moment closure equations of Levermore [C.D. Levermore, J. Stat. Phys {\\bf 83}, pp.1021 (1996)]. To the 1st-order expansion, the derived gas dynamic equations can be considered as a regularization of Levermore's 10 moments equations. The new gas dynamic equations have the same structure as the Navier-Stokes equations, but the stress strain relationship in ...

International Nuclear Information System (INIS)

The objective of this study was to develop a method for 3D subtraction CT angiography and to optimize the visualization after semiautomatic segmentation. Ten patients with aneurysms of the abdominal aorta were examined using spiral CT. To reconstruct the vessels, as well as adjacent organs such as the liver and kidneys, one image data volume was acquired before and after injection of the contrast agent. The CT scans were obtained with a Siemens Somatom Plus 4. To improve the results of automatic segmentation, as well as visualization by maximum intensity projection (i.e. removal of bony structures), subtraction of both image volumes is necessary. However, small translation shifts disturb the subtraction process and produce artificial contours. To calculate the disparities along the three coordinate axes of two corresponding image volumes, a cepstrum filter is applied to a pair of image volumes. After detection of the disparities, which manifest as bright spots, the ...

Energy Technology Data Exchange (ETDEWEB)

We demonstrate the rapid optical characterization of large numbers of individual metal nanoparticles freely diffusing in colloidal solution by confocal laser spectroscopy. We find that hollow gold nanospheres and solid silver nanoparticles linked with a bifunctional ligand, both designed nanostructures, exhibit significantly higher monodispersity in their Rayleigh and Raman scattering response than randomly aggregated gold and silver nanoparticles. We show that measurements of rotational diffusion timescales allow sizing of particles significantly more reliably than can be obtained using translational diffusion timescales.

Energy Technology Data Exchange (ETDEWEB)

A database has been developed to contain the disposal limits for the E-Area Low Level Waste Facility (ELLWF). This database originates in the form of an EXCEL{copyright} workbook. The pertinent sheets are translated to PDF format using Adobe ACROBAT{copyright}. The PDF version of the database is accessible from the Solid Waste Division web page on SHRINE. In addition to containing the various disposal unit limits, the database also contains hyperlinks to the original references for all limits. It is anticipated that database will be revised each time there is an addition, deletion or revision of any of the ELLWF radionuclide disposal limits.

International Nuclear Information System (INIS)

The book is a German translation of an American textbook with the original title ''MRI Survival Guide'' and is intended to serve as an introductory guide for beginners or a reference book for quick information. Readers will find information on the fundamentals of the technology and methodology of MRI as well as all details of relevance to practice in a precise and easy-to-grasp arrangement, covering all anatomic areas of interest, illustrations and descriptions of characteristic signs of pathologic processes, high-quality and unusually large-sized diagnostic pictures, a modern didactic concept for quick orientation, including surveys, tables, and reproductions for visualisation of contents. (orig./CB)

Science.gov (United States)

We explore autofluorescence endomicroscopy as a potential tool for real-time visualization of epithelial tissue microstructure and organization in a clinical setting. The design parameters are explored using two experimental systems--an Olympus Medical Systems Corp. stand-alone clinical prototype probe, and a custom built bench-top rigid fiber conduit prototype. Both systems entail ultraviolet excitation at 266 nm and/or 325 nm using compact laser sources. Preliminary results using ex vivo animal and human tissue specimens suggest that this technology can be translated toward in vivo application to address the need for real-time histology.

CERN Document Server

Safe operation of research reactors and critical assemblies

Science.gov (United States)

NASA's Ames Research Center awarded Ciencia, Inc., a Small Business Innovation Research contract to

Energy Technology Data Exchange (ETDEWEB)

EPRI research related to coal liquefaction has concentrated on the chemistry of the processes. Recent work is reviewed.

Wastenet

...PROJECTS We are funded by industry, public bodies, charities and research councils and we are proud of the research projects undertaken by our world-class research groups . Research News To read more about our latest research to hit the media go to our News & Events page ...

British Library Electronic Table of Contents (United Kingdom)

In many species social behaviors are dependent on integration of chemosensory and hormonal cues. Many chemosensory stimuli are detected by the vomeronasal organ, which projects to many regions that contain steroid receptors, including the medial amygdala. In male hamsters, testosterone is known to acutely increase in response to chemosensory stimulation, and can facilitate sexual behavior by direct action within the medial amygdala. Conspecific stimuli activate the anterior (MeA) and posterior (MeP) medial amygdala, while heterospecific stimuli activate only MeA. Chemosensory stimuli with different social significance differentially activate the dorsal and ventral subdivisions of MeA and MeP. Therefore, it is likely that steroids differentially facilitate stimulation of the medial amygdala...

International Nuclear Information System (INIS)

The world's fleet of nuclear power plants is, on average, more than 20 years old. Even though the design life of a nuclear power plant is typically 30-40 years, it is quite feasible that many plants will be able to operate in excess of their design lives, provided that nuclear power plant engineers demonstrate by analysis, trending, equipment and system upgrades, increased vigilance, testing and ageing management that the plant will operate safely. In the operation of nuclear power plants, safety should be always the prime consideration. Plant operators and regulators must always ensure that plant safety is maintained, and where possible enhanced, during a plant's operating lifetime. Nuclear power plant life management (PLiM) has gained increased attention over the past decade, and effective ageing management of systems, structures and components (SSCs) is a key element in PLiM for the safe and reliable long term operation of nuclear power plants. A PLiM programme is an effective tool ...

Energy Technology Data Exchange (ETDEWEB)

With the aid of a DOE grant (No. DE-FC26-01NT41050), Stolar Research Corporation (Stolar) developed the Horizon Sensor (HS) to distinguish between the different layers of a coal seam. Mounted on mining machine cutter drums, HS units can detect or sense the horizon between the coal seam and the roof and floor rock, providing the opportunity to accurately mine the section of the seam most desired. HS also enables accurate cutting of minimum height if that is the operator's objective. Often when cutting is done out-of-seam, the head-positioning function facilitates a fixed mining height to minimize dilution. With this technology, miners can still be at a remote location, yet cut only the clean coal, resulting in a much more efficient overall process. The objectives of this project were to demonstrate the feasibility of horizon sensing on mining machines and demonstrate that Horizon Sensing can allow coal to be cut cleaner and more ...

Science.gov (United States)

... Materials (PREM) Synopsis of Program: The objective of PREM is to enhance diversity in materials ... careers in materials research. The Partnerships for Research and Education in Materials (PREM ...

Science.gov (United States)

NSF-NIST Interaction in Chemistry, Materials Research, Molecular Biosciences, Bioengineering, and ... Laboratory (CSTL). Materials research is centralized in the Materials Science and Engineering ...

Science.gov (United States)

Jeffrey W. McCandless is a post-doctoral researcher at NASA Ames Research Center in the Human Factors Research and Technology Division.

UK PubMed Central (United Kingdom)

The paper describes advances in statistical methods for prevention research with a particular focus on substance abuse prevention. Standard analysis methods are extended to the typical research...Full Text Available

UK PubMed Central (United Kingdom)

Scyl1 is an evolutionarily conserved N-terminal protein kinase-like domain protein that plays a role in COP1-mediated retrograde protein trafficking in mammalian cells. Furthermore, loss of Scyl1 function...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Pumping is one of the means for storing vast quantities of energy. This article analyses its principles and ways of implementation with emphasis on its double aspect, e.g., on the one hand, off-peak power is transferred to the periods of heaviest load and is thus valorized, even when taking into account losses due to poor efficiency of operations in the pumping and turbine modes, and on the other hand, plants have great flexibility in operation, faciliting the permanent fitting of generation to demand.

Energy Technology Data Exchange (ETDEWEB)

This device has and head-race pipe with an external part and a coaxial inner part. A measuring head is mounted movable between these 2 parts and has at least a thermocouple and a mobile grid for varying the section and the sodium flow to facilitate the impurities dissolution. This ensemble is completed by a longitudinal body containing the main parts of the indicator and surrounded by a thermal exchanger to cool the sodium.

British Library Electronic Table of Contents (United Kingdom)

ABSTRACT Extending the unified theory of acceptance and use of technology (UTAUT) model, this study postulates a model of online social support. The model is empirically tested using data from undergraduates in Taiwan regarding their usage of instant messaging (IM). The test results indicate that all model paths are significant, except that the path between online social support and facilitating conditions is insignificant. This study offers limitations and implications.

DEFF Research Database (Denmark)

This article investigates the societal conditions that might help the establishment of peer-to-peer modes of production. First, the context within which such a new model is emerging - the neoliberal knowledge-based-societies - is described, and its shortcomings unveiled; and second, a robust argument is provided for the moral legitimation of an alternative societal vision, including two structural policies that are likely to facilitate the establishment and further development of peer-to-peer practices.

Environmental Research Database

DescriptionEnzymes are natural catalysts that are used increasingly to replace environmentally harmful chemicals and to achieve better catalytic selectivity during pulp and paper processing. The main objective of this project is to identify novel plant enzymes for deeper understanding of the process of fibre formation and for future improvement of the quality parameters of wood fibres. Specific modification of the fibre characteristics will facilitate their use as raw materials for the current pulp and pap [continued...

Wastenet

... 01, 2009 | Rate It Marine Technology Society https://www.mtsociety.org/home.aspx emphasizes the importance of marine technology as it applies to global issues, encourages marine technology education and facilitates the use of marine technology in managing marine resources Added: Mar. 11, 2010 |...

International Nuclear Information System (INIS)

In order to facilitate observations of low energy nuclear reactions, a new type recoil mass-separator together with a new gas-jet target system is being developed at the tandem accelerator facility in Kyushu University. The expected mass-resolving power of the separator is 220 for a solid angle of 10 msr and the practical thickness of the gas-jet target will exceed 0.1 atm#centre dot#cm for the light elements of H and He. (author).

Energy Technology Data Exchange (ETDEWEB)

Computer tomography used in the diagnosis of tumours is described in the light of particularly great diagnostic difficulties in children. Computer tomography was applied in 12 cases. A high diagnostic value of this method was demonstrated, which makes possible a more accurate diagnosis of the position of the tumour, its size, and expanding tendency. The possibility of estimating healthy tissues and organs, and those with pathological changes on the basis of differences in their density with a detection threshold at 0.5% density difference facilitates not infrequently preoperative diagnosis raising the value of the method.

Energy Technology Data Exchange (ETDEWEB)

The Atlantic Wind Test Site was established in 1980 as a laboratory to facilitate the evaluation and demonstration of wind energy systems and equipment. This annual report describes its organization and management, facilities, major projects, and the outlook for the future. Major projects include wind diesel; AWTS-IREQ collaboration; remote community data acquisition; lagerwey test program; Alaska Energy Authority Project; public education; Atlantic Orient Corporation 15/50 Project; and the soft VAWT project.

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

ScienceCinema

...different sparking language english ? ...

Environmental Research Database

No further description is available

Science.gov (United States)

...false Guidelines for Human Stem Cell Research Presidential Documents ...2009 Guidelines for Human Stem Cell Research Memorandum for the Heads...scientifically worthy human stem cell research, including human...

International Nuclear Information System (INIS)

The main trends of research carried out in remote handling systems in the fields of ergonomy, robotics and reliability are presented.

British Library Electronic Table of Contents (United Kingdom)

The influence of Confucian culture in Chinese Mainland China is reflected in the current situation and contextual trends of educational research content of educational thought of Confucianism, educational issues grounded on theoretical views of Confucianism, and the influence of the inclusiveness of Confucianism. In terms of research method, the current situation of educational research is reflected in empirical research whose methods value the construction of the metaphysical theoretical system, the guiding role of educational theories for educational reform practice, and research that enriches the literature. In terms of research value, the current situation of educational research is reflected in studies that focus on human nature, human relations, thoughts, willpower, emotion, human ri...

British Library Electronic Table of Contents (United Kingdom)

Abstract Toll-like receptor 2 (TLR2) is an immune sensor for gram-positive bacterial cell wall components. Single-nucleotide polymorphisms (SNPs) in the TLR2 gene that impair its function may, therefore, influence the risk and outcomes of gram-positive bacterial infections. In a cohort of 694 liver transplant recipients, we assessed the TLR2 SNP that is translated into an amino acid substitution of arginine for glutamine at position 753 (R753Q), and we found that its presence was associated with the clinical characteristics and outcomes of gram-positive bacterial infections. The proportions of patients with the TLR2 R753Q SNP did not significantly differ between those with gram-positive bacterial infections and those without gram-positive bacterial infections (9.6% versus 9.6%, P = 0.999)....

Energy Technology Data Exchange (ETDEWEB)

We have measured the almost-pure incoherent scattering function of liquid and solid parahydrogen, using inelastic neutron scattering. The experiments were carried out on TOSCA, a time-of-flight, inverse-geometry, crystal-analyzer spectrometer, operating on the pulsed neutron source at ISIS (UK). The experiments have been planned taking advantage of the intrinsic incoherence introduced in the scattering process by the rotational transitions. The measured double-differential cross section gives a direct experimental access to the microscopic dynamics of condensed hydrogen. From the high-energy region of the spectrum, where the impulse approximation for the center of mass motion applies, we have been able to extract the translational mean kinetic energy. In the low-energy region, using the Gaussian approximation, we compare the experimental data in the liquid phase with the results of a model for the velocity autocorrelation function. The results are encouraging, but ...

British Library Electronic Table of Contents (United Kingdom)

PurposeThe purpose of the present study was to compare the effect of submucosal versus intramuscular administration of dexamethasone sodium phosphate on patients' quality of life after surgical removal of impacted lower third molars. Patients and MethodsA randomized, non-blind, clinical trial was planned. The sample was composed of patients requiring extraction under local anesthesia of a single partial bony impacted mandibular third molar with Class II or III and position B or C, according to the Pell and Gregory classification. The patients were randomly distributed into 1 of 3 groups: submucosal dexamethasone, intramuscular dexamethasone, and a control group that received no steroid. A modified translated questionnaire was used to assess the patients' perception regarding different qual...

CERN Document Server

We present a simple discrete model for the non-linear spatial interaction ofdifferent kinds of ``subpopulations'' composed of identical moving entitieslike particles, bacteria, individuals, etc. The model allows to mimic a varietyof self-organized agglomeration and segregation phenomena. By relating it togame-theoretical ideas, it can be applied not only to attractive and repulsiveinteractions in physical and chemical systems, but also to the much richercombinations of positive and negative interactions found in biological andsocio-economic systems. Apart from investigating symmetric interactions relatedto a continuous increase of the ``overall success'' within the system(``self-optimization''), we will focus on cases, where fluctuations further orinduce self-organization, even though the initial conditions and theinteractions are assumed homogeneous in space (translation invariant).

British Library Electronic Table of Contents (United Kingdom)

Recently, we cloned purpurin cDNA as an upregulated gene in the axotomized fish retina. The retina-specific protein was secreted from photoreceptors to ganglion cell layer during an early stage of optic nerve regeneration in zebrafish retina. The purpurin worked as a trigger molecule for axonal regrowth in adult injured fish retina. During zebrafish development, purpurin mRNA first appeared in ventral retina at 2 days post-fertilization (dpf) and spread out to the outer nuclear layer at 3 dpf. Here, we investigated the role of purpurin for zebrafish retinal development using morpholino gene knockdown technique. Injection of purpurin morpholino into the 1-2 cell stage of embryos significantly inhibited the transcriptional and translational expression of purpurin at 3 dpf. In the purpurin mo...

Energy Technology Data Exchange (ETDEWEB)

With steam generator check testing, the numerous types of defect not only have to be detected reliably but also to be identified correctly and classified according to depth. A priori, no signals are provided by the physical eddy-current mechanism, i.e. the disturbance of an excited eddy-current field by a defect, which will allow unambiguous identification and classification of the defects. The task, therefore, consists in designing the eddy-current method in terms of measurement technology in such a way as to obtain useful detection, identification and classification by a translation of the signals as simple and as save as possible. Internal through-flow wils and internal rotating probes were examined for their suitability to fulfill this three-pronged task with steam generator inspection.

Energy Technology Data Exchange (ETDEWEB)

A new power system stabilizer (PSS) design method for single-machine infinite-bus systems is developed. This design method not only assigns the poles corresponding to the electro-mechanical oscillation modes in the system, but also located other system poles in suitable places in the s-plane. The design procedure is used first to translate a PSS design problem to an equivalent constant output feedback controller design problem for a single-input multi-output (SIMO) system. Then, a new algorithm developed in this paper is applied to design a constant output feedback controller to achieve the desired closed-loop system pole locations. Finally, the controller gains are transferred back to the parameters in the PSS. The extension of the method to multi-machine power systems is also illustrated. (Author).

Energy Technology Data Exchange (ETDEWEB)

Over 170 participants from 60 countries met for three days in Copenhagen from 7 to 9 June 1994 to discuss howe the aims of the United Nations Framework convention on Climate Change can be translated into practical action. The Conference was organised by the UNEP collaborating Centre on Energy and Environment (UCCEE), with financial support from the Danish International Development Agency (Danida), the Global Environment Facility (GEF), the United Nations Environment Programme (UNEP) and Risoe National Laboratory, Denmark. The main objective of the conference was to identify common approaches to national mitigation analysis for countries to use in meeting their commitments under the FCCC, and in setting priorities for national actions. Although addressing a broader theme, the conference marked the completion and publication of the second phase on UNEP Greenhouse Gas Abatement Costing Study. (au)

Energy Technology Data Exchange (ETDEWEB)

The advent of carbon nanotubes, which are graphite layers convoluted in cylinders several nanometers in diameter and several micrometers in length, as well as the experiments on implanting metal atoms in such tubes open the way to producing nanoconductors and other materials with unique properties. For theorists, the basic challenge is interpreting and predicting the structure and properties of these systems. The linearized augmented-plane-wave method (LAPW) is one of the most accurate methods in the theory of the electronic structure of solids. A generalization of this method for quasi-two-dimensional systems, surface electronic states, and layered crystals is known. The LAPW theory for quasi-unidimensional systems, which exhibit translational symmetry in one direction, has been absent thus far. In this paper, the authors suggest a version of such a theory and use this method to calculate the electronic structure of carbyne (a linear chain of carbon atoms) and ...

CERN Document Server

We study dipolar bosons in a 1D optical lattice and identify a region in parameter space---strong coupling but relatively weak on-site repulsion---hosting a series of stable CDW states whose low-energy excitations, built from "fractional domain walls", are remarkably similar to those of non-abelian fractional quantum Hall states. Here, a conventional domain wall between translated CDW's may split by inserting strings of degenerate, but inequivalent, CDW states. Outside these insulating regions, we find numerous supersolids as well as a superfluid regime. The mentioned phases should be accessible experimentally, and in particular, the fractional domain walls can be created in the ground state using single-site addressing, i.e. by locally changing the chemical potential.

CERN Document Server

Although good encryption functions are probabilistic, most symbolic models do not capture this aspect explicitly. A typical solution, recently used to prove the soundness of such models with respect to computational ones, is to explicitly represent the dependency of ciphertexts on random coins as labels. In order to make these label-based models useful, it seems natural to try to extend the underlying decision procedures and the implementation of existing tools. In this paper we put forth a more practical alternative based on the following soundness theorem. We prove that for a large class of security properties (that includes rather standard formulations for secrecy and authenticity properties), security of protocols in the simpler model implies security in the label-based model. Combined with the soundness result of (\\textbf{?}) our theorem enables the translation of security results in unlabeled symbolic models to computational security.

British Library Electronic Table of Contents (United Kingdom)

Summary A prospective and randomized trial design is of utmost interest when it comes to evaluating new developments in the management of cardiovascular medicine. By defining the primary end point and a profound related statistic new therapeutic options can be tested with an adequate number of patients. The course of the trial is supervised by a Clinical Events Committee and a Data and Safety Monitoring Board. Registries are promising tools for describing how the results of clinical trials are translated into daily practice. Their drawbacks include lack of control of the clinical endpoints and their uniform definition and lack of a control group. There are numerous examples from cardiology of the limited usefulness of data obtained from registry studies with their often unexpected results ...

British Library Electronic Table of Contents (United Kingdom)

A mechanism is proposed for the previously observed [1] jump in erythrocyte fluidity through a microcapillary 1.3 ?m in diameter at a temperature of 36.6?0.3?C. Our interpretation is based on the experimental evidence both for existence of ortho and para H2O isomers in water and on spin-selective interaction of proteins with para H2O isomers as hydration shells of biomolecules are being formed [2]. It is important that the formation of hydration shells of proteins and DNA in aqueous solutions is accompanied by an increase in the Brillouin shift to 0.4 cm?1 (?0.25 cm?1 in water), which points to the formation of icelike structures. We believe that the coincidence of the translational energy kT of the Brownian motion and the energy of the rotational quanta for the 313?202 transition of para ...

Energy Technology Data Exchange (ETDEWEB)

Several proposals have been made on the method of calculating generation of formaldehyde released from plywood. In calculating generation per hour of a volatile organic compound of adhesives or coatings using a chamber method, such models are frequently used that the generation is largest when the specimen is exposed in the chamber and that the generation attenuates with lapse of time. In the meantime, a number of studies for calculating formaldehyde generation from construction materials are often those determining a specific quantity of generation in a stationary state, while few studies are the observation of time series variation from immediately after the exposure into the chamber. Accordingly, the subject studies used lauan plywood as the samples and examined the method of calculating the change with lapse of time of the formaldehyde generation. (translated by NEDO)

International Nuclear Information System (INIS)

Techniques of chemical analysis, amino acid sequencing and autoradiography are being used to study the frequency of incorporation of normally noncoded amino acids into hemoglobins and seminal fluid proteins. We are studying, by the sequencing of radiolabeled proteins followed by the recovery of ["3H] isoleucine phenylthiohydantoin by high-performance liquid chromatography, the frequency at which normally noncoded isoleucine is incorporated into hemoglobin because of base-substitution mutations versus translational errors. Irradiation increases the isoleucine content of human hemoglobin and the frequency of substitution of isoleucine for specific amino acids in rabbit hemoglobin. Studies to date indicate that these techniques have been developed sufficiently for initial analysis of the potential of drugs and environmental pollutants to induce base-substitution mutations in mammalian somatic cells.

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The developed system is intended for use at a collimated thermal neutron beam with a flux of about 10{sup 6} n/cm{sup 2} s. The system works with a cooled CCD array (192 x 165 pixels) and an intensifier for light from a NE426 scintillator with traditional optical coupling. A fine mechanical regulation system allows an accurate positioning of the tomographer, also ensuring the alignment of the CCD array with the rotation and translation axes. The acquisition of 200 projections is carried out in about 30 min with a reconstruction time (40 min max) depending on the reconstruction-matrix order. Radiography and tomography of significant objects are illustrated. The reconstruction algorithm, including spatial and temporal inhomogeneity corrections and filters, was tested with good results for projections up to 512 x 512 pixels. (orig.)

Energy Technology Data Exchange (ETDEWEB)

This is the final report of the Finnish Research Programme on Climate Change (SILMU). This report includes the final results and conclusions made by the individual research groups. The aim of this report is to lay out the research work, and to present the main results and conclusions obtained during the six-year work. The Finnish Research Programme on Climate Change (SILMU) was a multidisciplinary national research programme on climate and global change. The principal goals of SILMU were: (1) to increase our knowledge on climate change, its causes, mechanisms and consequences, (2) to strengthen the research on climate change in Finland, (3) to increase the participation of Finnish researchers in international research programmes, and (4) to prepare and disseminate information for policy makers on adaptation and ...

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Large rigid-body domain movements are critical to GroEL-mediated protein folding, especially apical domain elevation and twist associated with the formation of a folding chamber upon binding ATP and co-chaperonin GroES. Here, we have modeled the anisotropic displacements of GroEL domains from various crystallized states, unliganded GroEL, ATP?S-bound, ADP-AlFx/GroES-bound, and ADP/GroES bound, using translation-libration-screw (TLS) analysis. Remarkably, the TLS results show that the inherent motions of unliganded GroEL, a polypeptide-accepting state, are biased along the transition pathway that leads to the folding-active state. In the ADP-AlFx/GroES-bound folding-active state the dynamic modes of the apical domains become reoriented and coupled to the motions of bound GroES. The ADP/GroES complex exhibits these same motions, but they are increased in magnitude, potentially reflecting the decreased stability of the complex after nucleotide hydrolysis. Our results ...

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Commercially-available nuclear fixturing systems typically include a square lattice of tapped and bushed holes with precision locating and clamping elements that can be rigidly attached to the lattice using dowel pins or expanding mandrels. Currently, human expertise is required to synthesize a suitable arrangements of these elements to hold a given part. Besides being time consuming, if the set of alternatives is not systematically explored, the designer may fail to find an acceptable fixture or may settle upon a suboptimal fixture. We consider a class of modular fixtures that prevent a part from translating or rotting in the plane using four point contacts on the part`s boundary. These fixtures are based on three round locators, each centered on a lattice point, and one translating clamp. We present an algorithm that accepts a polygonal part shape as input and synthesizes the set of all fixture designs that achieve form closure for the given ...

Energy Technology Data Exchange (ETDEWEB)

This paper was presented at the opening plenary session. As the end of the century approaches, environmental protection is one of the most significant global issues which will shape our energy path and economic development pattern. In face of environmental challenges, we will have to take into account environmental factors in the economic development process itself. This requires the pursuit of sustainable economic development, a process which may involve strengthened energy conservation, improved efficiency and switching to less carbon intensive energy sources. Energy inefficiency, technological scarcity and financial vulnerability in developing countries may best be resolved by changing their economic and market structures to facilitate relevant investments. However, effective reform of the energy industry in developing economies and economies in transition will also require international cooperation in terms of transfer of technology, capital, know-how and ...

Energy Technology Data Exchange (ETDEWEB)

Lawrence Livermore National Laboratory (LLNL) is implementing an Internet-based process pilot called `Zephyr` to streamline engineering and commerce using the Internet. Major benefits have accrued by using Zephyr in facilitating industrial collaboration, speeding the engineering development cycle, reducing procurement time, and lowering overall costs. Programs at LLNL are potentializing the efficiencies introduced since implementing Zephyr. Zephyr`s pilot functionality is undergoing full integration with Business Systems, Finance, and Vendors to support major programs at the Laboratory.

British Library Electronic Table of Contents (United Kingdom)

According to Schumpeter, the creative process of economic development can be divided into the stages of invention, innovation (commercialization) and imitation. Each stage is associated with specific skills. This paper examines whether Schumpeter?s assertion was correct, i.e. whether the invention and innovation stages should be undertaken by different agents. In addition, we examine whether there is a rationale for the Schumpeterian entrepreneur to include the inventor in the commercialization process. Combining the abilities of the entrepreneur and the inventor may serve to facilitate customer adaptation, strengthen knowledge transfers and reduce uncertainty, thereby expanding market opportunities. Based on a unique database covering Swedish patents granted to individuals and small firms...

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Surface doping of conjugated polymers is realized by depositing a thin layer of graphene oxide (GO) on top of the polymers. The high proton density and the unique 2D structure of GO facilitate the protonic surface doping of conjugated polymers to achieve high conductivities. This finding represents a new strategy for improving charge transport across the metal/conjugated polymer interface to achieve much improved performance in organic solar cells. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

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Oral mucositis associated with head and neck radiotherapy can substantially hinder completion of cancer therapy. Alleviation of this often severe stomatitis can provide enhanced patient comfort and facilitate appropriate care. A double-blind format was used in a pilot project to measure, against a control rinse, the effectiveness of an oral rinse consisting of hydrocortisone, nystatin, tetracycline, and diphenhydramine in controlling radiation-related mucositis. A combination of clinical evaluation and patient responses to a questionnaire was used to judge the results of the topical medications. Patients using the experimental medication developed less mucositis than did patients in the control group.

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Microorganisms are ubiquitous in subsurface environments although their populations sizes and metabolic activities can vary considerably depending on energy and nutrient inputs. As a result of their metabolic activities and the chemical properties of their cell surfaces and the exopolymers they produce, microorganisms can directly or indirectly facilitate the biotransformation of radionuclides, thus altering their solubility and overall fate and transport in the environment. Although biosorption to cell surfaces and exopolymers can be an important factor modifying the solubility of some radionuclides under specific conditions, oxidation state is often considered the single most important factor controlling their speciation and, therefore, environmental behavior.

International Nuclear Information System (INIS)

The atlas presents sequences of MRI sections parallel to the orbito-meatal plane in children from birth through the age of sixteen years. Each child was studied horizontally and sagitally and three-dimensional brain images were reconstructed to facilitate accurate identification of sulci and gyri. The images show crucial aspects of brain development such as the constancy of the brain stem and primitive brain from birth onward; the development of the telencephalon, characterized by deepening of sulci and growth of the cerebral cortex surface; and the different stages of white matter myelinization.

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The Knowledge Associates for Novel Intelligence (KANI) system provides a collection of automated 'associates' to actively support and participate in the information analysis task. In this paper, we describe the Information Integration Associate (IIA), which facilitates analyst interaction with underlying KANI reasoning and extraction associates and provides an interactive representation of the analytic process. We focus on features of the IIA that guide communication between the user and the KANI system in a way that ensures mutual understanding of the analytic task being performed, the capabilities of the system to assist the user, and the status of any reasoning and extraction conducted on behalf of the user by the KANI system.

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The polymerization of vinyl pyrrolidinone on nylon 66, with the assistance of aqueous phenol and formic acid, was investigated by mutual and post irradiation procedures. Both solvents were found to greatly facilitate the polymerization with the post irradiation procedure, whereas neither presented any advantage with the mutual irradiation procedure. Tensile properties of the modified fibers were affected in similar ways by both the irradiation procedures and solvents in that the only notable changes were the somewhat higher extensions at yield and at break. The moisture regain values of the treated yarns and fabrics were increased up to three-fold. Surface morphology of the modified fibers was revealed by SEM.

International Nuclear Information System (INIS)

A database has been compiled on human dietary intakes of trace elements by populations groups living in various countries. The main sources of information used were (1) publications in the open scientific literature, and (2) data submitted to the IAEA in response to a questionnaire. The database contains 1,758 intake values covering 35 elements and 47 countries. In this report the data are listed in various ways to facilitate identification of intake values for any specified country, element and population group. 4 refs, 5 tabs.

British Library Electronic Table of Contents (United Kingdom)

Purpose - The purpose of this paper is to place all of the contributions to this special issue into a theoretical framework and to highlight the role that the so-called "information age mindset" has in the facilitation of employability skills. Design/methodology/approach - The paper discusses the major themes of this special issue. Findings - Undergraduate students do see the importance of technological innovation in the classroom but they see the development of experiential or work-based skills to be more important. Practical implications - Future curriculum design should consider the expectations and attitudes of the modern day undergraduate student to ensure that potential employability is maximised. Originality/value - The findings are placed into the wider context of the emerging fiel...

British Library Electronic Table of Contents (United Kingdom)

The purpose of this study is to clarify the confusing nomenclature and pathogenesis of Developmental Facial Paralysis, and how it can be differentiated from other causes of facial paralysis present at birth. Differentiating developmental from traumatic facial paralysis noted at birth is important for determining prognosis, but also for medicolegal reasons. Given the dramatic presentation of this condition, accurate and reliable guidelines are necessary in order to facilitate early diagnosis and initiate appropriate therapy, while providing support and counselling to the family. The 30 years experience of our center in the management of developmental facial paralysis is dependent upon a thorough understanding of facial nerve embryology, anatomy, nerve physiology, and an appreciation of well...

Energy Technology Data Exchange (ETDEWEB)

Absorption with aqueous amine solvents is at present the most viable technology for CO{sub 2} capture. While this is a proven technology, efforts are ongoing to improve it in order to make it a more attractive technology for large scale use to reduce CO{sub 2} emissions. Finding solvents with better properties is one approach to improving the technology. In this thesis methods in computational chemistry are used to improve the understanding of the chemistry of CO{sub 2} absorption in amine-water systems. The work is also intended to provide models that can be used to predict the performance of new solvents. Such predictive models are intended to facilitate the screening for new solvents

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The Coal Corporation of Victoria's mission is to initiate, facilitate and co-ordinate brown coal-based developments, other than for electricity generation, to provide maximum long-term benefits to Victoria including new jobs, new technology, new investment and new products, within sound environmental parameters. The marketing of brown coal products is vigorously undertaken to provide the financial and business base for the Corporation. This report contains a review of the Corporation's activities and achievements during 1989/90.

Science.gov (United States)

The first candidate rotavirus vaccine was a live attenuated oral vaccine made by the classical empirical method of serial passage of virus in tissue culture cells. Current tetravalent vaccine candidates that are in the final stages of efficacy testing in the United States were made by genetic reassortment. This article briefly highlights how advances in the basic understanding of the molecular biology of rotaviruses have facilitated vaccine development. New approaches for second-generation vaccines and improvements in vaccine efficacy based on further exploitation of the tools and knowledge of rotavirus molecular biology and pathogenesis are discussed. PMID:8752289

International Nuclear Information System (INIS)

Radiology departments often underestimate the importance of protecting medical data during transmission, including the precautions taken to ensure data protection. In teleradiology, transmitted as well as stored patient data have to be signed digitally according to the currently valid regulation (Roentgenverordnung, RoeV). The DICOM standard facilitates a digital signature. So far, medical image manufacturers only announced to support this security feature. We introduce a solution that extends the feature of digital signing to older modalities. (orig.)

Science.gov (United States)

Special education researchers have made noteworthy progress toward conceptualizing literacy research questions, designing quality studies, and disseminating the results of their research. These advancements have been made through the establishment and refinement of quality research indicators. Unfortunately, this progress has mostly eluded the arena of juvenile justice special education research. The purpose of this article is to review juvenile justice literacy studies and provide juvenile justice personnel and researchers with methodological and practical considerations for improving the quality of juvenile justice literacy research. The focus is on advancing group designs. Practical concerns are based on the first-year experiences of researchers who implemented an Institute of Education Sciences Goal 3 study with the ...

International Nuclear Information System (INIS)

In the early sixties it was decided to investigate salt formations on its suitability to host heat generating radioactive waste in Germany. In the reference repository concept consequently the emplacement of vitrified waste canisters in deep vertical boreholes inside a salt mine was considered whereas spent fuel should be disposed of in self shielding casks (type POLLUX) in horizontal drifts. The POLLUX casks, 65 t heavy carbon steel casks, will be laid down on the floor of a horizontal drift in one of the disposal zones to be constructed in the salt dome at the 870 m level. The space between casks and drift walls will be backfilled with crushed salt. The transport, the handling und the emplacement of POLLUX casks were subject of successfully performed demonstration and in situ tests in the nineties and resulted in an adjustment of the atomic law. The borehole disposal concept comprises the emplacement of unshielded canisters with vitrified HLW in boreholes with a diameter of 60 cm and ...

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The report presents selected highlights of how research has contributed to the regulatory effort. It explains the research role of the NRC and nuclear safety research contributions in the areas of: pressure vessel integrity, piping, small- and large-break loss-of-coolant accidents, hydrogen and containment, source term analysis, seismic hazards and high-level waste management. The report also provides a summary of current and future research directions in support of regulation.

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Topics Research Results Research Results by Date Study Shows Chamomile Capsules Ease Anxiety Symptoms Chamomile © Karen Bergeron Generalized anxiety disorder (GAD) has a wide...

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... based, disease treatment remains promising, the emphasis for stem cell research from the biomedical research community is clear, and ... diagnosis as a novel source of embryos for stem cell research. Repr...

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Materials World Network: Cooperative Activity in Materials Research between US Investigators and ... Program Title: Materials World Network: Cooperative Activity in Materials Research between US ...

Medline Plus

September 14, 2010 ADHD: Signs, Symptoms, Research NIMH researchers talk about the symptoms of ADHD as well as the latest research. Download this video. Watch on YouTube. Transcript Announcer: ADHD- Attention Deficit Hyperactivity Disorder- is one of the ...

Wastenet

... After completing a review into direct coal liquefaction research carried out in Australia and internationally, CSIRO has identified potential new science and technology developments that may improve the cost and viability of CTL in a greenhouse gas-constrained environment. We are conducting research to: determine the optimum ...

Science.gov (United States)

... 1995 Trilateral Materials Workshop PDF (202K) Report of the Workshop on Materials for Future ... in Materials Research Technology and Education PDF (163K) US-Asian Pacific Materials Research ...

Science.gov (United States)

The unsteady aerodynamic forces of a model fruit fly wing in flapping motion were investigated by numerically solving the Navier-Stokes equations. The flapping motion consisted of translation and rotation [the translation velocity (u(t)) varied according to the simple harmonic function (SHF), and the rotation was confined to a short period around stroke reversal]. First, it was shown that for a wing of given geometry with u(t) varying as the SHF, the aerodynamic force coefficients depended only on five non-dimensional parameters, i.e. Reynolds number (Re), stroke amplitude (Phi), mid-stroke angle of attack (alpha(m)), non-dimensional duration of wing rotation (Delta tau(r)) and rotation timing [the mean translation velocity at radius of the second moment of wing area (U), the mean chord length (c) and c/U were used as reference velocity, length and time, respectively]. Next, the force coefficients were investigated for a ...

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... The revised work plan emphasized the research priorities of preharvest rodent damage to rice, the importance of postharvest food losses to rodents ...

Science.gov (United States)

as one of the first Materials Research Laboratories to be funded by the forerunner of DARPA. In 1972 funding was taken over by the National Science Foundation's Division of...

International Nuclear Information System (INIS)

In this paper, an attempt is made to outline the priority areas for research in human nutrition in India that could be tackled by appropriate application of stable isotope technology. 10 refs.

Science.gov (United States)

The general goals of this research effort is to explore the potential applications and performance of fine grained computer architectures for vision. The body of this report gives a brief overview of the results of the research during the first twelve mon...

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health research agency, NIMH is dedicated to reducing the burden of mental and behavioral disorders through research on mind, brain, and behavior. As part of that mission, NIMH...

British Library Electronic Table of Contents (United Kingdom)

In this paper I argue that when a researcher is a research instrument, it is likely that the researcher would develop a heightened awareness of his/her own cultural conditioning, especially in the case of cross-cultural studies. And that such awareness would make him/her realise that one's own cultural background may indeed have an influence on formulating his/her research methodology. The paper is based on my own research project on development cooperation between Japan and Cambodia, whereby I examined the perceptions of Cambodians and Japanese on what an appropriate power relationship between donors and recipients should be. At the outset of my research project, I paid little attention to my own cultural condition and the role it might play in my study, though I was aware that being Japa...

UK PubMed Central (United Kingdom)

A review of the literature is provided for the topic of health-related research and power frequency electromagnetic fields. Minimal evidence for concern is present on the basis of animal and plant research....Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Recommendations of the Advisory Committee on Reactor Safeguards are presented to the Commissioners for their consideration for FY 82 budget for the NRC safety research program.

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... 4? Program History 5? Center for Advanced Materials and Smart Structures 6? Center for Systems ... Systems 14? Center for Photonic Materials Research 15? Synthesis, Manufacturing and Characterization ...

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For the purpose of digging up themes of the joint research which develop the R and D in the industrial technology field in Japan to a new stage, researchers were sent to the world representing research institutes to conduct the research survey of 'Nano-structured carbon and hydrogen absorption' and 'Development of the creation technology of nano-porous materials.' As to the former, an experiment on electrochemical hydrogen absorption of carbon materials including nanotubes was conducted by researchers dispatched, but the large absorption amount was not observed. As to the latter, visits were paid to Fraunhofer Institute and the related facilities in Germany, Princeton University, MIT, GIT and Naval Research Laboratories in the U.S., Orleans University in France, AO Research Institute (bone repair study) in ...

Science.gov (United States)

Myostatin is a member of the transforming growth factor-{beta} (TGF-{beta}) family and a strong negative regulator of muscle growth. Here, we present the crystal structure of myostatin in complex with the antagonist follistatin 288 (Fst288). We find that the prehelix region of myostatin very closely resembles that of TGF-{beta} class members and that this region alone can be swapped into activin A to confer signalling through the non-canonical type I receptor Alk5. Furthermore, the N-terminal domain of Fst288 undergoes conformational rearrangements to bind myostatin and likely acts as a site of specificity for the antagonist. In addition, a unique continuous electropositive surface is created when myostatin binds Fst288, which significantly increases the affinity for heparin. This translates into stronger interactions with the cell surface and enhanced myostatin degradation in the presence of either Fst288 or Fst315. Overall, we have identified several ...

CERN Document Server

In order to perform a detailed study of the stellar kinematics in the vertical axis of bars, we obtained high signal-to-noise spectra along the major and minor axes of the bars in a sample of 14 face-on galaxies, and used them to determine the line of sight stellar velocity distribution, parameterized as Gauss-Hermite series. With these data, we developed a diagnostic tool that allows one to distinguish between recently formed and evolved bars, as well as estimate their ages, assuming that bars form in vertically thin disks, recognizable by low values for the vertical velocity dispersion sigma_z. Through N-body realizations of bar unstable disk galaxies we could also check the time scales involved in the processes which give bars an important vertical structure. We show that sigma_z in evolved bars is roughly around 100 Km/s, which translates to a height scale of about 1.4 Kpc, giving support to scenarios in which bulges form through disk material. Furthermore, the ...

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The reversion time migration, as one of reflection seismic prospecting migration, reverse propagates a wave equation by reverse promoting the differential time, and conducts the migration. The method has such merits as no limit to the inclined angle of a reflection, correspondence to a complex topography etc. And, there is a finite difference time domain (FDTD) that uses the Maxwell equation as it is and makes a difference approximation in the methods differentiating and resolving electro-magnetic fields. It is also possible to apply the reverse time migration onto it. In this speech, using an explosive reflection face, a slope 2 layer structure and models of its reflection points are synthesized by a ground penetrating radar using the FDTD, and reverse time migration is conducted. As a result, it is clarified that the reverse time migration is valid for the ground penetrating radar recording. And, the cases including a diffusion item in the equation are also studied. ...

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In this experiment, a beam incident from an oblique direction is reflected by a spherical lens toward the direction of incidence. When the surface of a matter is vibrated by elastic waves, the spherical lens comes into a translation motion that accompanies the vibration. It follows accordingly that the vibration on the surface of the matter may be detected by sensing the spherical lens travelling speed. Three components of the vibration may be determined if beams are focused at one spot from three directions. Detection of the S-wave component by LDV (laser Doppler vibrometer) discloses the complicated wave field in a heterogeneous material, and this physical model experiment may be utilized in various fields of study. For instance, information about problems that may surface in the field work may be collected beforehand in a physical model experiment for developing an S-wave-aided probing method. For the study of seismic wave propagation in a complicated ...

Energy Technology Data Exchange (ETDEWEB)

The electricity industry in the US today is at a crossroads. The restructuring debate going on in most regions has made it clear that the traditional model of vertically integrated firms serving defined franchise areas and regulated by state commissions may not be the pattern for the future. The demands of large customers seeking direct access to power markets, the entry of new participants, and proposed reforms of the regulatory process all signify a momentum for fundamental change in the organization of the industry. This paper addresses electricity restructuring from the perspective of bulk power markets. The authors focus attention on the organization of electricity trade and the various ways it has been and might be conducted. Their approach concentrates on conceptual models and empirical case studies, not on specific proposals made by particular utilities or commissions. They review literature in economics and power system engineering that is relevant to the major questions. The ...

Science.gov (United States)

We analyze cross sections for quasielastic inclusive scattering of electrons on nuclei and show that the observed isolated peaks for relatively low Q{sup 2} are unique for the lightest targets. Focusing, in particular, on D and {sup 4}He, we investigate in two ways to what measure the above peaks can be allocated to nucleon-elastic processes. We first compute approximate upper limits for the nucleon-inelastic background in the quasielastic region due to inclusive {delta} excitation, and find those to be small. Far more precise is a semiphenomenological approach, where the dominance of nucleon-elastic processes is translated into a set of stringent requirements. We show that those are very well fulfilled for recent D data, and to a somewhat lesser extent for older D and {sup 4}He data. With knowledge of G{sub E,M}{sup p} and information on G{sub E}{sup n}, we then extract G{sub M}{sup n} and find agreement with values obtained by alternative methods. We discuss the ...

Science.gov (United States)

The Energy crisis happens to be one of the greatest challenges we are facing today. In this view, much effort has been made in developing new, cost effective, environmentally friendly energy conversion and storage devices. The performance of such devices is fundamentally related to material properties. Hence, innovative materials engineering is important in solving the energy crisis problem. One such innovation in materials engineering is porous materials for energy storage. Porous electrode materials for lithium-ion batteries (LIBs) offer a high degree of electrolyte-electrode wettability, thus enhancing the electrochemical activity within the material. Among the porous materials, mesoporous materials draw special attention, owing to shorter diffusion lengths for Li+ and electronic movement. Nanostructured mesoporous materials also offer better packing density compared to their nanostructured counterparts such as nanopowders, nanowires, nanotubes etc., thus opening a window for ...