eccentric muscle contractions: Topics by WorldWideScience.org

The impact of a repeated bout of eccentric exercise on muscular strength, muscle soreness and creatine kinase.

Objective: Hamstring injuries can be quite debilitating and often result in chronic problems. Eccentric muscle actions are often the last line of defense against muscle injury...Full Text Available

1998-07-01

3

Regulation of Na(+)-K+ pump activity in contracting rat muscle.

The purpose of this study was to determine if there were any beneficial or detrimental effects regarding delayed onset muscle soreness (DOMS), serum creatine kinase (CK), and maximum concentric strength...Full Text Available

1994-12-01

4

ALTERATION OF THE PKC-MEDIATED SIGNALING PATHWAY FOR SMOOTH MUSCLE CONTRACTION IN OBSTRUCTION-INDUCED HYPERTROPHY OF THE URINARY BLADDER

1. In rat soleus muscle, high frequency electrical stimulation produced a rapid increase in intracellular Na+ (Na+i) content. This was considerably larger in muscles contracting without developing tension...Full Text Available

1997-09-15

5

Muscle Forces or Gravity: What Predominates Mechanical Loading on Bone?

Normal urinary bladder function requires contraction and relaxation of the detrusor smooth muscle (DSM). The DSM undergoes compensatory hypertrophy in response to partial bladder outlet obstruction...Full Text Available

2009-07-01

6

Redox state changes in human skeletal muscle after isometric contraction.

Most mechanical forces acting on the skeleton are generated either through impact with the ground (i.e., gravitational loading) or through muscle contractions (i.e., muscle loading). If one...Full Text Available

2009-11-01

7

Role of adenosine in regulating glucose uptake during contractions and hypoxia in rat skeletal muscle

Subjects maintained an isometric contraction of the quadriceps femoris muscle at two-thirds maximal voluntary contraction (m.v.c.) force for 5 s (5.0 +/- 0.3 s; mean +/- S.E. of mean; n = 6) or until...Full Text Available

1986-11-01

8

Muscle glycogen content and glucose uptake during exercise in humans: influence of prior exercise and dietary manipulation

The effect of A₁-adenosine receptor antagonism via 8-cyclopentyl-1,3-dipropyl-xanthine (CPDPX) on the stimulation of skeletal muscle glucose uptake by...Full Text Available

1999-02-15

9

Repriming the actomyosin crossbridge cycle

There are many factors that can influence glucose uptake by contracting skeletal muscle during exercise and although one may be intramuscular glycogen content, this relationship is at present not fully...Full Text Available

2002-05-15

10

Estimation of elbow flexion force during isometric muscle contraction from mechanomyography and electromyography

The central features of the mechanical cycle that drives the contraction of muscle are two translational steps: the working stroke, whereby an attached myosin crossbridge moves relative to the actin...Full Text Available

2004-08-31

11

British Library Electronic Table of Contents (United Kingdom)

Mechanomyography (MMG) is the muscle surface oscillations that are generated by the dimensional change of the contracting muscle fibers. Because MMG reflects the number of recruited motor units and their firing rates, just as electromyography (EMG) is influenced by these two factors, it can be used to estimate the force exerted by skeletal muscles. The aim of this study was to demonstrate the feasibility of MMG for estimating the elbow flexion force at the wrist under an isometric contraction by using an artificial neural network in comparison with EMG. We performed experiments with five subjects, and the force at the wrist and the MMG from the contributing muscles were recorded. It was found that MMG could be utilized to accurately estimate the isometric elbow flexion force based on the v...

2010-01-01

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Transient increase in glucose 1,6-bisphosphate in human skeletal muscle during isometric contraction.

Contraction-mediated inactivation of glycogen synthase is accompanied by inactivation of glycogen synthase phosphatase in human skeletal muscle.

Changes in glucose 1,6-bisphosphate and regulators of glucose-1,6-bisphosphate synthase and phosphatase during isometric contraction have been determined. Biopsies were obtained from the quadriceps...Full Text Available

1989-03-15

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Effect of endurance training on glucose transport capacity and glucose transporter expression in rat skeletal muscle

Activities of glycogen synthase (GS) and GS phosphatase were determined on human muscle biopsies before and after isometric contraction at 2/3 maximal voluntary force. Total GS activity did not change...Full Text Available

1989-05-01

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Relationships between contraction properties of knee extensor muscles and fasting IGF-1 and adipocytokines in physically active postmenopausal women

The effect of 10 wk endurance swim training on 3-O-methylglucose (3-MG) uptake (at 40 mM 3-MG) in skeletal muscle was studied in the perfused rat hindquarter. Training resulted in an increase of approximately 33% for maximum insulin-stimulated 3-MG transport in fast-twitch red fibers and an increase of approximately 33% for contraction-stimulated transport in slow-twitch red fibers compared with nonexercised sedentary muscle. A fully additive effect of insulin and contractions was observed both in trained and untrained muscle. Compared with transport in control rats subjected to an almost exhaustive single exercise session the day before experiment both maximum insulin- and contraction-stimulated transport rates were increased in all muscle types in trained rats. Accordingly, the increased glucose transport capacity in trained ...

1990-12-01

15

British Library Electronic Table of Contents (United Kingdom)

Summary The aim of this cross-sectional study was to find possible relationships between insulin-like growth factor-1 (IGF-1), adipocytokines (leptin and adiponectin) and twitch contraction (TC) characteristics of the knee extensor (KE) muscles in healthy physically active postmenopausal women (n = 28, 64-78 years old). We hypothesized that IGF-1 is related at least to isometric TC peak torque (Pt) as the highest value of isometric torque production and maximal voluntary contraction (MVC) torque, and there will not be any relationships between TC characteristics and leptin and adiponectin. During the measurement of MVC torque and twitch contractile properties of KE muscles, the subjects sat in a custom-made dynamometric chair with the knee and hip angles equal to 90degree and 100degree, re...

2010-01-01

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Signal transduction underlying the control of urinary bladder smooth muscle tone by muscarinic receptors and ?-adrenoceptors

["3H]QNB binding and contraction of rabbit colonic smooth muscle cells

The normal physiological contraction of the urinary bladder, which is required for voiding, is predominantly mediated by muscarinic receptors, primarily the M₃ subtype, with the M₂...Full Text Available

2008-06-01

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A Study on the Relationship between the Eccentricity and the Level of Damage in the Seismic Response of Buildings with Plan Irregularities

The authors used radioligand binding and studies of cell contraction to characterize muscarinic receptors on dispersed smooth muscle cells from rabbit proximal and distal colon. Cells obtained after serial incubations in collagenase were used to measure binding of tritiated quinuclidinyl benzilate (["3H]QNB). At 37 degree C, specific ["3H]QNB binding was saturable and linearly related to cell number. Nonlinear regression analysis was used to determine the affinity of ["3H]QNB for its receptor. The IC_5_0 for the muscarinic agonists bethanechol and oxotremorine were 80 and 0.57 #mu#M, respectively. Hill coefficients were 0.67 for both, suggesting more complex interaction involving receptors of different affinities. In studies of cell contraction, bethanechol stimulated a dose-dependent decrease in cell length with half the maximal contraction occurring at 100 pM. These results suggest that (1) ...

1987-01-01

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Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle.

Full Text Available

2010-06-01

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Effect of fatiguing exercise on longitudinal bone strain as related to stress fracture in humans.

We previously reported that the peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) mRNA in rat epitrochlearis muscle was increased after swimming exercise training. In the present study, we demonstrated further that PGC-1 mRNA expression in the epitrochlearis muscle of 4-5-week-old male Sprague-Dawley rats was increased after a 6-h acute bout of low-intensity swimming exercise. With this increase, the expression level was approximately 8-fold of control and immersion group rats that stayed for 6-h in warm water, maintained at the identical temperature of the swimming barrel (35 degrees C) (p<0.01). Second, PGC-1 mRNA expression in the muscle was found to have increased 6-h after 30 10-s tetani contractions were induced by in vitro electrical stimulation. Finally, PGC-1 mRNA expression in the muscle incubated for 18-h with 0.5mM 5-aminoimidazole-4-carboxamide ...

2002-08-16

20

On the orbital evolution and growth of protoplanets embedded in a gaseous disc

Muscular fatigue in the training athlete or military recruit has been hypothesized to cause increased bone strain that may contribute to the development of a stress fracture. Under normal circumstances, muscles exert a protective effect by contracting to reduce bending strains on cortical bone surfaces. In vivo strain studies in dogs show that muscle fatigue following strenuous exercise elevates bone strain and changes strain distribution. However, a similar experiment has yet to be performed in humans. The purpose of this work was to test the hypothesis in humans that strenuous fatiguing exercise causes an elevation in bone strain. It was also hypothesized that this elevation is greater in younger people than in older people due to the decline in muscle strength and endurance that normally occurs with age. To test these hypotheses, strain in the tibiae of seven human volunteers was measured during ...

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Eccentric conical fastening system

We present a new computation of the linear tidal interaction of a protoplanetary core with a thin gaseous disc in which it is fully embedded. For the first time a discussion of the orbital evolution of cores with eccentricity (e) significantly larger than the gas-disc scale height to radius ratio (H/r) is given. We find that the direction of orbital migration reverses for e>1.1H/r. This occurs as a result of the orbital crossing of resonances in the disc that do not overlap the orbit when the eccentricity is very small. Simple expressions giving approximate fits to the eccentricity damping rate and the orbital migration rate are presented. We go on to calculate the rate of increase of the mean eccentricity for a system of protoplanetary cores due to dynamical relaxation. By equating the eccentricity damping time-scale with the dynamical relaxation time-scale we deduce that an ...

1999-01-01

22

[Thoracic muscle activity during cooling].

Fastening systems for parts that endure high vibration shear loads have traditionally been difficult or expensive to produce. This application describes a fastening system with multiple conical surfaces and eccentric offsets. The novel conical fastener system allows parts to be assembled with reduced tolerance controls at interface features while improving alignment precision. The eccentric conical fastening system is particularly well suited for assemblies with high shear loads in high vibration/shock environments, and/or for systems that have extremely precise pointing requirements.

2008-11-25

23

Benzyl carbamyl analogue of lignocaine: vasodepressor mechanism of action.

PMID:4423540

1974-05-01

24

Interactions of -lactoglobulin with serotonin and arachidonyl serotonin

1. The benzyl carbamyl analogue of lignocaine [2-(diethylaminoacetamido)-3-carbamyl-4-methyl-5-benzylpyrrole] at an intravenous dose of 4 mg/kg caused a blood pressure decrease of 54 mmHg. 2. A greater hypotensive effect was observed in hypertensive compared to normotensive animals. Anaesthesia magnified the vasodepressor effect in both groups. 3. The analogue did not possess centrally-mediated effects on blood pressure but exerted its hypotensive effect via a peripheral mechanism. 4. The analogue produced a relaxant effect on intestinal and vascular smooth muscle while exerting minimal effects on muscarinic, sympathetic, or ganglionic nicotinic receptors. 5. The analogue exhibited less cardiac depressant action on left ventricular rate (dp/dt) and force of contraction than lignocaine. 6. Lethal effects for the analogue were first observed at 16 mg/kg following intravenous administration and at 500 mg/kg following intraperitoneal ...

25

British Library Electronic Table of Contents (United Kingdom)

Abstract -Lactoglobulin (-LG) is a lipocalin, which is the major whey protein of cow's milk and the milk of other mammals. However, it is absent from human milk. The biological function of -LG is not clear, but its potential role in carrying fatty acids through the digestive tract has been suggested. -LG has been found in complexes with lipids such as butyric and oleic acids and has a high affinity for a wide variety of compounds. Serotonin (5-hydroxytryptamine, 5-HT), an important compound found in animals and plants, has various functions, including the regulation of mood, appetite, sleep, muscle contraction, and some cognitive functions such as memory and learning. In this study, the interaction of serotonin and one of its derivatives, arachidonyl serotonin (AA-5HT), with -LG was invest...

2011-01-01

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INTERACTING BINARIES WITH ECCENTRIC ORBITS. III. ORBITAL EVOLUTION DUE TO DIRECT IMPACT AND SELF-ACCRETION

[Morpho-functional features of the innervation of intracartilaginous muscles in cats].

The rapid circularization and synchronization of the stellar components in an eccentric binary system at the onset of Roche lobe overflow is a fundamental assumption common to all binary stellar evolution and population synthesis codes, even though the validity of this assumption is questionable both theoretically and observationally. Here we calculate the evolution of the orbital elements of an eccentric binary through the direct three-body integration of a massive particle ejected through the inner Lagrangian point of the donor star at periastron. The trajectory of this particle leads to three possible outcomes: direct accretion onto the companion star within a single orbit, self-accretion back onto the donor star within a single orbit, or a quasi-periodic orbit around the companion star, possibly leading to the formation of a disk. We calculate the secular evolution of the binary orbit in the first two cases and conclude that direct impact ...

2010-11-20

27

[Chest muscle activity during thermal dyspnea].

PMID:123866

1975-03-01

28

Smooth Muscle Hypertrophy Following Partial Bladder Outlet Obstruction Is Associated with Overexpression of Non-Muscle Caldesmon

PMID:4462663

1974-09-01

29

Muscle-Specific Calpain is Localized in Regions Near Motor Endplates in Differentiating Lobster Claw Muscles

Partial bladder outlet obstruction (PBOO) induces remodeling of urinary bladder smooth muscle (detrusor). We demonstrate an increase in bladder wall mass, muscle bundle size, and a threefold increase...Full Text Available

2004-02-01

30

Relaxant effects of hexosamines on isolated small human placental arteries

Calpains are Ca²⁺-dependent proteinases that mediate protein turnover in crustacean skeletal muscles. We used an antibody directed against lobster muscle-specific calpain (Ha-CalpM)...Full Text Available

2007-11-01

31

Effect of propylbenzilylcholine mustard on contraction and radioligand binding parameters of muscarinic receptors in guinea pig ileum

Wharton's jelly contains large amounts of hyaluronic acid, and glucosamine is an important constituent of this macromolecule. In order to evaluate the placental vascular effects of this aminosugar, small chorionic and stem villous arteries were dissected from placental specimens obtained at normal term vaginal deliveries (n = 15). Ring preparations were mounted in organ baths, and isometric wall tensions were measured. Glucosamine and its epimer galactosamine (5 X 10(-4) to 10(-2) M) produced marked relaxation of contractions induced by PGF2 alpha (10(-5) M) in both chorionic and stem villous arteries. The effect was unchanged after pretreatment with atropin, propranolol and indomethacin. The relaxant effect of the neutral sugar mannose was less pronounced compared with that of the hexosamines. Total tissue concentrations of placental hexosamines have been reported within the range needed to produce placental vascular relaxation in the present study. However, the ...

1987-01-01

32

Expansionary fiscal contractions : Re-evaluating the Danish case

The receptor occupancy-biological effect relationship for muscarinic receptors in guinea pig ileal smooth muscle has been studied by comparison of radioligand binding and contractile response. Muscarinic receptors in homogenates of ileal smooth muscle were labeled with (/sub 3/H)-1-Quinuclidinyl benzilate. Treatment with propylbenzilylcholine mustard (PrBCM), to inactivate irreversibly muscarinic receptors, caused a large dose dependent rightward shift of the dose-response curve to three agonistic furtrethonium derivatives with a concomitant decrease in maximal response. Using those data, the fraction of receptors remaining unoccupied (q-values) and true affinity constants (-log K/sub A/-values) were calculated. Exposure to 20 or 60 nM PrBCM for 15 minutes resulted in a 39% and a 61% reduction in specific (/sup 3/H)-1-Quinuclidinyl benzilate binding sites respectively to be compared with a 62% and a 85% decrease expected from calculated ...

1987-10-26

33

Development of linear flow rate control system for eccentric butter-fly valve

Udgivelsesdato: March

2010-01-01

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Modulation of leg muscle function in response to altered demand for body support and forward propulsion during walking

Butter-fly valves are advantageous over gate, globe, plug, and ball valves in a variety of installations, particularly in the large sizes. The purpose of this project development of linear flow rate control system for eccentric butter-fly valve (intelligent butter-fly valve system). The intelligent butter-fly valve system consist of a valve body, micro controller. The micro controller consist of torque control system, pressure censor, worm and worm gear and communication line etc. The characteristics of intelligent butter-fly valve system as follows: Linear flow rate control function. Digital remote control function. guard function. Self-checking function. (author)

1999-12-01

35

Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle

A number of studies have examined the functional roles of individual muscles during normal walking, but few studies have examined which are the primary muscles that respond to changes in external...Full Text Available

2009-05-11

36

Tea catechins prevent contractile dysfunction in unloaded murine soleus muscle: A pilot study

Muscular dystrophies (MDs) comprise a group of degenerative muscle disorders characterized by progressive muscle wasting and often premature death. The primary defect common to most MDs involves disruption...Full Text Available

2011-03-01

37

British Library Electronic Table of Contents (United Kingdom)

ObjectiveExtended periods of muscle disuse, physical inactivity, immobilization, and bedrest result in a loss of muscle mass and a decrease in muscle force, which are accompanied by an increase in oxidative stress. We investigated the effects of the intake of green tea catechins on unloading-induced muscle dysfunction in tail-suspended mice. MethodsTen-week-old male BALB/c mice were fed a purified control diet or a diet containing 0.5% tea catechins for 14 d. Thereafter, the mice were subjected to continuous tail suspension for 10 d. On the final day, muscle mass, contractile force production, antioxidant potential, and carbonylated protein levels were evaluated. ResultsHind limb unloading caused a loss of soleus muscle weight and muscle force. Intake of tea catechins significantly inhibit...

2011-01-01

38

Optical Diffraction Studies of Muscle Fibers

OBSERVATIONS ON THE VARIATIONS IN SIZE OF THE A REGION OF ARTHROPOD MUSCLE

A new technique to monitor light diffraction patterns electrically is applied to frog semitendinosus muscle fibers at various levels of stretch. The intensity of the diffraction lines, sarcomere length...Full Text Available

1973-09-01

39

Gracilis Muscle Transposition for Iatrogenic Rectourethral Fistula

The muscles of three different arthropods, a mite, a fly, and an ostracod, show variations in the length of the A region within a given individual. There is no indication that the observed differences...Full Text Available

1963-11-01

40

The Acute Effect of Trimetazidine on the High Frequency Fatigue in the Isolated Rat Diaphragm Muscle

ObjectiveTo assess the utility of gracilis muscle transposition in the treatment of iatrogenic rectourethral fistula.Summary Background DataIatrogenic...Full Text Available

2003-04-01

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The prevalence of absence of the palmaris longus muscle in the Bahraini population

Full Text Available

2004-06-01

42

Ganglion Cysts

Medline Plus

... many bones. The bones are separated by special hinges called joints. Muscles make the bones move on ...

43

British Library Electronic Table of Contents (United Kingdom)

Abstract Absence of the palmaris longus muscle has been well documented in several populations at a prevalence rate ranging between 2.2 and 63.9% which varies according to race, sex, and side of the body. There is little documentation of the prevalence of absence of this muscle from populations in the Arabian Gulf region. We examined 1,043 subjects, 3 85 years old, from the Kingdom of Bahrain for the presence or absence of the palmaris longus muscle using the conventional test for the presence of this muscle. Statistical analyses investigated the association of muscle absence with sex, hand dominance, and laterality. The palmaris longus muscle was absent in 36.8% of subjects. Bilateral absence (19%) was more common than unilateral absence (17.9%) with preponderance in female subjects. The ...

2010-01-01

44

Forward contracts in electricity markets: The Australian experience

Proposal for the award of a blanket purchase contract for the supply of electronics subracks for the CERN accelerator control system

Forward contracts play a vital role in all electricity markets, and yet the details of the market for forward contracts are often opaque. In this paper we review the existing literature on forward contracts and explore the contracting process as it operates in Australia. The paper is based on interviews with participants in Australia's National Electricity Market (NEM). The interviews were designed to understand the contracting process and the practice of risk management in the Australian energy-only pool market. This survey reveals some significant gaps between the assumptions made in the academic literature and actual practice in the Australian market place. (author)

2007-05-01

45

NSSC Transition Schedule By Service - NASA

Proposal for the award of a blanket purchase contract for the supply of electronics subracks for the CERN accelerator control system

2010-01-01

46

Opto-acoustic recanilization delivery system

MSC PATRAN & NASTRAN Licenses Contract (Transitioned Jun 2006). COTR Training Recompetition (Awarded Jan 2007). Closeout Services Contract ...

47

Comprehensive simulations of superhumps

Fiber delivered laser pulses emulsify thrombus by mechanical stresses that include a combination of pressure, tension and shear stress. Laser radiation is delivered to the locality of a thrombus and the radiation is absorbed by blood, blood dot, or other present materials. The combination of a leading pressure wave and subsequent vapor bubble cause efficient, emulsification of thrombus. Operating the laser in a low average power mode alleviates potential thermal complications. The laser is operated in a high repetition rate mode to take advantage of ultrasound frequency effects of thrombus dissolution as well as to decrease the total procedure time. Specific parameter ranges for operation are described. The device includes optical fibers surrounding a lumen intended for flow of a cooling agent. The fibers may be arranged concentrically around the lumen to deliver radiation and heat over as large an area as possible. An alternative design approach incorporates the optical fibers into ...

2002-01-01

48

Loss of contraction force in dermal fibroblasts with aging due to decreases in myosin light chain phosphorylation enzymes

(Abridged) We use 3D SPH calculations with higher resolution, as well as with more realistic viscosity and sound-speed prescriptions than previous work to examine the eccentric instability which underlies the superhump phenomenon in semi-detached binaries. We illustrate the importance of the two-armed spiral mode in the generation of superhumps. Differential motions in the fluid disc cause converging flows which lead to strong spiral shocks once each superhump cycle. The dissipation associated with these shocks powers the superhump. We compare 2D and 3D results, and conclude that 3D simulations are necessary to faithfully simulate the disc dynamics. We ran our simulations for unprecedented durations, so that an eccentric equilibrium is established except at high mass ratios where the growth rate of the instability is very low. Our improved simulations give a closer match to the observed relationship between superhump period excess and binary ...

2007-01-01

49

Illuminating Cell Biology

Full Text Available

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Vitamin C and E Supplementation Effects in Professional Soccer Players Under Regular Training

NASA's Ames Research Center awarded Ciencia, Inc., a Small Business Innovation Research contract to

2002-01-01

51

Utility of CT in the diagnosis of psoitis

Exercise training is known to induce an increase in free radical production potentially leading to enhanced muscle injury. Vitamins C and E are well known antioxidants that may prevent muscle cell damage....Full Text Available

52

Transversal Stiffness and Young's Modulus of Single Fibers from Rat Soleus Muscle Probed by Atomic Force Microscopy

A 65-year-old woman who was diagnosed as having psoitis by CT findings, which disclosed non-symmetrical dilation of the psoas muscle and gaseous image. Pus from the psoas muscle seen at surgery corresponded to CT findings. Preoperative CT examination was useful in the establishment of diagnosis. (Namekawa, K.).

1984-01-01

53

The fibre type composition of thoracic and lumbar paravertebral muscles in man.

AbstractThe structural integrity of striated muscle is determined by extra-sarcomere cytoskeleton that includes structures that connect the Z-disks and M-bands of a sarcomere to sarcomeres...Full Text Available

2010-02-03

54

The Functional Role of Calcineurin in Hypertrophy, Regeneration, and Disorders of Skeletal Muscle

Samples of longissimus and multifidi muscles at the thoracic and lumbar levels of the spine were examined histochemically on autopsy specimens from 21 adult male subjects (aged 22 to 46 years) and on...Full Text Available

1985-08-01

55

Targeted gene transfection from microbubbles into vascular smooth muscle cells using focused, ultrasound-mediated delivery

Skeletal muscle uses calcium as a second messenger to respond and adapt to environmental stimuli. Elevations in intracellular calcium levels activate calcineurin, a serine/threonine phosphatase, resulting...Full Text Available

2010-01-01

56

Stimulation of albumin endocytosis by cationized ferritin in cultured aortic smooth muscle cells.

We investigate a method for gene delivery to vascular smooth muscle cells using ultrasound triggered delivery of plasmid DNA from electrostatically coupled cationic microbubbles. Microbubbles...Full Text Available

2010-09-01

57

Anionic microdomains within the aortic smooth muscle cell (SMC) surface glycocalyx represent a potential barrier to the endocytosis of anionic plasma proteins. Cultured SMCs exposed briefly to cationized...Full Text Available

1985-12-01

58

SARCOLEMMAL INVAGINATIONS CONSTITUTING THE T SYSTEM IN FISH MUSCLE FIBERS

SummaryThe structure and function of myosin crossbridges in asynchronous insect flight muscle (IFM) have been elucidated in situ using multiple approaches. These...Full Text Available

2008-09-05

59

Regional Muscle and Whole-Body Composition Factors Related to Mobility in Older Individuals: A Review

Striated muscle fibers from the body and tail myotomes of a fish, the black Mollie, have been examined with particular attention to the sarcoplasmic reticulum (SR) and transverse tubular (or T) system....Full Text Available

1964-09-01

60

Pretreatment with a soluble activin type IIB receptor/Fc fusion protein improves hypoxia-induced muscle dysfunction

ABSTRACTPurpose: To describe previously reported locomotor muscle and whole-body composition factors related to mobility in older individuals.Methods:...Full Text Available

2009-01-01

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P2X purinoceptors mediate an endothelium-dependent hyperpolarization in longitudinal smooth muscle of anterior mesenteric artery in young chickens

Hypoxia, or reduced oxygen, occurs in a variety of clinical and environmental situations. Hypoxic exposure is associated with decreased muscle mass and a concomitant reduction in exercise capacity,...Full Text Available

2010-01-01

62

Muscle strength, endurance, and aerobic capacity in rheumatoid arthritis: a comparative study with healthy subjects.

Background and purpose:The chicken anterior mesenteric artery contains an outer longitudinal smooth muscle layer, whose neural regulation remains to be elucidated. ATP evokes a depolarization...Full Text Available

2009-10-01

63

Muscle satellite cell proliferation and association: new insights from myofiber time-lapse imaging

Isometric/isokinetic muscle strength and isokinetic endurance of the lower extremities as well as aerobic capacity were evaluated in 67 patients (43 female, 24 male; mean age 53 years, range 23-65)...Full Text Available

1992-01-01

64

Measurement of the quadriceps femoris muscle using magnetic resonance and ultrasound imaging.

BackgroundAs the resident stem cells of skeletal muscle, satellite cells are activated by extracellular cues associated with local damage. Once activated, satellite cells will re-enter...Full Text Available

65

Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration

OBJECTIVES: To define a method for measurement of the cross sectional area and volume of the quadriceps femoris muscle using magnetic resonance imaging (MRI) in conjunction with stereology, and to compare...Full Text Available

1997-03-01

66

Increased SRF transcriptional activity in human and mouse skeletal muscle is a signature of insulin resistance

Oxidative stress has been implicated in the etiology of age-related muscle loss (sarcopenia). However, the underlying mechanisms by which oxidative stress contributes to sarcopenia have not been thoroughly...Full Text Available

2010-05-01

67

Impact of physical training on the ultrastructure of midthigh muscle in normal subjects and in patients treated with glucocorticoids.

Insulin resistance in skeletal muscle is a key phenotype associated with type 2 diabetes (T2D) for which the molecular mediators remain unclear. We therefore conducted an expression analysis of human...Full Text Available

2011-03-01

68

Impact of Lifelong Sedentary Behavior on Mitochondrial Function of Mice Skeletal Muscle

Exercise-training might be a logical method to reverse muscle atrophy and weakness in patients treated with glucocorticoids. The purpose of the present investigation was to establish whether a treatment...Full Text Available

1987-04-01

69

Imaging of calcium transients in skeletal muscle fibers.

This study investigated the impact of lifelong sedentariness on skeletal muscle mass and mitochondrial function. Thirty C57BL/6 strain mice (2 months) were randomly divided into three groups (young-Y;...Full Text Available

2009-09-01

70

Functional pools of oxidative and glycolytic fibers in human muscle observed by 31P magnetic resonance spectroscopy during exercise.

Epifluorescence images of Ca2+ transients elicited by electrical stimulation of single skeletal muscle fibers were studied with fast imaging techniques that take advantage of the large fluorescence...Full Text Available

1991-01-01

71

Flexible Muscle Modes and Synergies in Challenging Whole-Body Tasks

Quantitative probing of heterogeneous regions in muscle is feasible with phosphorus-31 magnetic resonance spectroscopy because of the differentiation of metabolic patterns of glycolytic and oxidative...Full Text Available

1987-12-01

72

Fetal tissue sampling--indications, techniques, complications, and experience with sampling of fetal skin, liver, and muscle.

We used the idea of hierarchical control to study multi-muscle synergies during a whole-body sway task performed by a standing person. Within this view, at the lower level of the hierarchy,...Full Text Available

2008-08-01

73

Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats

Invasive prenatal testing has become an important way to evaluate fetuses at increased risk for hereditary disorders. In utero sampling of fetal skin, liver, and muscle may be required to diagnose before-birth...Full Text Available

1993-09-01

74

Exact moment of tendon of pectoralis major muscle rupture captured on video

Silent information regulators are potent NAD⁺-dependent protein deacetylases, which have been shown to regulate gene silencing, muscle differentiation and DNA damage repair. Here,...Full Text Available

2010-01-01

75

Energy metabolism of the untrained muscle of elite runners as observed by 31P magnetic resonance spectroscopy: evidence suggesting a genetic endowment for endurance exercise.

A powerlifting athlete ruptured his left tendon of the pectoralis major muscle while attempting to lift 160 kg in a Brazilian bench press championship. The injury seemed to occur in the concentric...Full Text Available

2007-09-01

76

Effects of Naja nivea venom on nerve, cardiac and skeletal muscle activity of the frog

The purpose of this study was to investigate whether genetically determined properties of muscle metabolism contribute to the exceptional physical endurance of world-class distance runners. ATP, phosphocreatine,...Full Text Available

1988-12-01

77

Decelerating burst and complex repetitive discharges in the striated muscle of the urethral sphincter, associated with urinary retention in women.

1. The effects of 1 mg/ml whole Naja nivea (Cape cobra) venom, and of three different toxins isolated from it, on spinal reflex excitability and cardiac and skeletal muscle activity...Full Text Available

1973-03-01

78

Control of wrist position and muscle relaxation by shifting spatial frames of reference for motoneuronal recruitment: possible involvement of corticospinal pathways

A type of electromyographic activity, formerly referred to as "pseudomyotonia", can be recorded from the striated muscle of the urethral sphincter using a concentric needle electrode. There are two...Full Text Available

1985-10-01

79

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

It has previously been established that muscles become active in response to deviations from a threshold (referent) position of the body or its segments, and that intentional motor actions result from...Full Text Available

2010-05-01

80

Kenneth M. Baldwin - Astrobiology - NASA

Acquired resistance to the action of insulin to stimulate glucose transport in skeletal muscle is associated with obesity and promotes the development of type 2 diabetes. In skeletal muscle,...Full Text Available

2008-05-01

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Functional strategies of the hindlimb muscles in the mouse deer

Feb 11, 1997 ... Dr. Baldwin's research focuses on understanding the mechanisms of skeletal and cardiac muscle adaptations to hormonal and activity ...

82

Changes in muscular lipids in unilateral isolated hypertrophy of gastrocnemius muscle can be revealed by 1H MR spectroscopy.

... were larger in TFLM, BFM, QFM, PM and TSM in the mouse deer than in the two ... ...

83

Acute interleukin-6 administration does not impair muscle glucose uptake or whole-body glucose disposal in healthy humans.

Full Text Available

2009-12-01

84

Extended amino acid sequences around the active-site lysine residue of class-I fructose 1,6-bisphosphate aldolases from rabbit muscle, sturgeon muscle, trout muscle and ox liver.

Udgivelsesdato: 2003-Apr-15

2003-01-01

85

Small heat shock protein 20 (HspB6) in cardiac hypertrophy and failure

1. Amino acid sequences covering the region between residues 173 and 248 [adopting the numbering system proposed by Lai, Nakai & Chang (1974) Science 183, 1204-1206] were derived for trout (Salmo...Full Text Available

1979-11-01

86

British Library Electronic Table of Contents (United Kingdom)

Hsp20, referred to as HspB6, is constitutively expressed in various tissues. Specifically, HspB6 is most highly expressed in different types of muscle including vascular, airway, colonic, bladder, and uterine smooth muscle; cardiac muscle; and skeletal muscle. It can be phosphorylated at Ser-16 by both cAMP- and cGMP-dependent protein kinases (PKA/PKG). Recently, Hsp20 and its phosphorylation have been implicated in multiple physiological and pathophysiological processes including smooth muscle relaxation, platelet aggregation, exercise training, myocardial infarction, atherosclerosis, insulin resistance and Alzheimer's disease. In the heart, key advances have been made in elucidating the significance of Hsp20 in contractile function and cardioprotection over the last decade. This mini-rev...

2011-01-01

87

Effect of season on contractile and metabolic properties of desert camel muscle (Camelus dromedarius)

British Library Electronic Table of Contents (United Kingdom)

Thirty fattened one humped desert camels were used to examine the effect of season on contractile and metabolic properties of Longissimus thoracis (LT) muscle. Ten camels were slaughtered according to seasons of the year (winter, summer and autumn). Season significantly influenced muscle chemical composition, ultimate pH (pHu) and color. Activities of metabolic enzymes were higher during autumn season compared to summer and winter for phosphofructokinase (+64% compared to both seasons) and for isocitrate dehydrogenase (+35% and +145% in autumn vs. summer and winter, respectively). Quantification of muscle myosin heavy chain isoforms by SDS-PAGE electrophoresis showed only presence of type I and type IIa MyHC in camel muscle and indicated high proportion in winter for type I and in autumn f...

2012-01-01

88

Spitting versus Biting: Differential Venom Gland Contraction Regulates Venom Expenditure in the Black-Necked Spitting ...

Proposal for the award of a contract, without competitive tendering, for the replacement of lift machine room equipment and the installation of remote monitoring systems

... 1670/07-076.1 Spitting versus Biting: Differential Venom Gland Contraction Regulates Venom Expenditure in the Black-Necked Spitt...

89

IAEA RESEARCH CONTRACTS. THIRD ANNUAL REPORT. Technical Reports Series No. 16

Proposal for the award of a contract, without competitive tendering, for the replacement of lift machine room equipment and the installation of remote monitoring systems

2011-01-01

90

Academic Health Systems Management: The Rationale Behind Capitated Contracts

Brief summaries of all final reports relating to contracts that were completed during 1962 are presented. 20 summaries are included. (P.C.H.)

1963-01-01

91

Update of the Navy Contract Writing Guide

ObjectiveTo determine why hospitals enter into “capitated” contracts, which often generate accounting losses. The authors’ hypothesis is that hospitals coordinate...Full Text Available

2000-06-01

92

Models of cardiac electromechanics based on individual hearts imaging data

... These requirements may be expressed in terms of MIL-STD-2073-1, DoD Material Procedures for Development and Application of Packaging ...

2004-06-01

93

British Library Electronic Table of Contents (United Kingdom)

Current multi-scale computational models of ventricular electromechanics describe the full process of cardiac contraction on both the micro- and macro- scales including: the depolarization of cardiac cells, the release of calcium from intracellular stores, tension generation by cardiac myofilaments, and mechanical contraction of the whole heart. Such models are used to reveal basic mechanisms of cardiac contraction as well as the mechanisms of cardiac dysfunction in disease conditions. In this paper, we present a methodology to construct finite element electromechanical models of ventricular contraction with anatomically accurate ventricular geometry based on magnetic resonance and diffusion tensor magnetic resonance imaging of the heart. The electromechanical model couples detailed repres...

2011-01-01

94

IAEA Co-ordinated Research Program (CRP)

Small hemielliptic dielectric lens antenna analysis in 2-D: boundary integral equations versus geometrical and physical optics

The Coordinated Research Project is a topical collection of research agreements and contracts. The research contracts are awarded with financial support of about 10-20% of the total contract cost. Among the activities of the project is the organization of consultant group meetings and workshops involving several international experts and representatives of users and developers of border radiation monitoring equipment. The project also supports in coordinating the development of equipment and techniques for up-to-date border monitoring and in establishing of a process for providing nuclear forensics support to member states

2010-05-19

95

SPH simulations of accretion flow via Roche lobe overflow and via mass transfer from Be disk

We assess the accuracy and relevance of the numerical algorithms based on the principles of Geometrical Optics (GO) and Physical Optics (PO) in the analysis of reduced-size homogeneous dielectric lenses prone to behave as open resonators. As a benchmark solution, we use the Muller boundary integral equations discretized with trigonometric Galerkin scheme that has guaranteed and fast convergence as well as controllable accuracy. The lens cross-section is chosen typical for practical applications, namely an extended hemiellipse whose eccentricity satisfies the GO focusing condition. The analysis concerns homogeneous lenses made of rexolite, fused quartz, and silicon with the size varying between 3 and 20 wavelengths in free space. We consider the 2-D case with both E- and H-polarized plane waves under normal and oblique incidence, and compare characteristics of the near fields.

2010-01-01

96

Discovery of a Red Giant with Solar-like Oscillations in an Eclipsing Binary System from Kepler Space-based Photometry

We compare the accretion flow onto the neutron star induced by Roche lobe overflow with that by the overflow from the Be disk, in a zero eccentricity, short period binary with the same mass transfer rate, performing three-dimensional Smoothed Particle Hydrodynamics simulations. We find that a persistent accretion disk is formed around the neutron star in both cases. The circularization radius of the material transferred via Roche lobe overflow is larger than that of the material transfered from the Be disk. Thus, the growth of the accretion disk in the former case becomes significantly slower than in the latter case. In both cases, the mass accretion rate is very small and varies little with orbital phase, which is consistent with the observed X-ray behaviour of Be/X-ray binaries with circular orbits (e.g. XTE J1543-568).

2005-01-01

97

Bone scanning after muscle-pedicle bone graft for femoral neck fracture, (1). Preliminary report

Oscillating stars in binary systems are among the most interesting stellar laboratories, as these can provide information on the stellar parameters and stellar internal structures. Here we present a red giant with solar-like oscillations in an eclipsing binary observed with the NASA Kepler satellite. We compute stellar parameters of the red giant from spectra and the asteroseismic mass and radius from the oscillations. Although only one eclipse has been observed so far, we can already determine that the secondary is a main-sequence F star in an eccentric orbit with a semi-major axis larger than 0.5 AU and orbital period longer than 75 days.

2010-01-01

98

The skeletal muscle ryanodine receptor identified as a molecular target of[3H] azidodantrolene by photoaffinity labeling

sup(99m)Tc-MDP bone scintigraphy was performed on patients who received muscle-pedicle bone graft. In each of the bone head and the bone graft, a time-activity curve was obtained. In this muscle-pedicle bone graft, active revascularization and marked osteogenesis, which suggested rapid bone repairing, were observed. The bone scintigraphy was considered to be useful in observing the result of bone grafts, blood circulation, and time of bone fusion, and of value for early detection of secondary changes.

1982-04-01

99

The segmental gastrocnemius muscles' flap: A cadaveric study

... 16, 2001 0006-2979 BIORAK v. 40(2) APPLIED LIFE SCIENCES azido

2001-04-01

100

British Library Electronic Table of Contents (United Kingdom)

The aim of this study was to evaluate the feasibility of splitting each head of the gastrocnemius muscle into two segments. This prospective study was conducted on 35 fresh cadavers with injection of radio-opaque contrast material in the popliteal artery. Seventy medial gastrocnemius and 70 lateral gastrocnemius muscle specimens were obtained. Gastrocnemius intramuscular arterial anatomy was analysed by using the digital X-ray technique. The most common vascular pattern found in this study was both bellies supplied by individual sural arteries, which shows distal bifurcation. The medial sural artery always showed bifurcation in the medial gastrocnemius muscle in both lower limbs, whereas this bifurcation of the lateral sural artery was present in only 87% cases and 13% of cases showed a si...

2011-01-01

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101

The effect of the venom of the yellow Iranian scorpion Odontobuthus doriae on skeletal muscle preparations in vitro

British Library Electronic Table of Contents (United Kingdom)

The yellow Iranian scorpion Odontobuthus doriae can cause fatal envenoming, but its mechanism of action is unclear. One of the reported manifestations of envenoming is moderate to severe involuntary tremor of skeletal muscle. In order to understand better the mechanism of action of this venom on skeletal muscle function, we examined the effects of the venom in vitro on chick biventer cervicis (CBC) and mouse hemidiaphragm (MHD) nerve muscle preparations. O. doriae venom (0.3-10mg/ml) initially increased and then decreased twitch height. The venom also caused contracture in both preparations. In mouse triangularis sterni preparations, used for all intracellular recording techniques, the venom enhanced the release of acetylcholine and induced repetitive firing of nerve action potentials and ...

2007-01-01

102

Phospholemman: A Novel Cardiac Stress Protein

Patients receiving maintenance dialysis have more severe functionally significant skeletal muscle wasting than patients with dialysis-independent chronic kidney disease.

Phospholemman (PLM), a member of the FXYD family of regulators of ion transport, is a major sarcolemmal substrate for protein kinases A and C in cardiac and skeletal muscle. In the heart, PLM...Full Text Available

2010-08-01

103

Iodination of glyceraldehyde 3-phosphate dehydrogenase

PMID:16504974

2006-02-27

104

Functional Consequences of Sarcopenia and Dynapenia in the Elderly

1. A high degree of homology in the positions of tyrosine residues in glyceraldehyde 3-phosphate dehydrogenase from lobster and pig muscle, and from yeast, prompted an examination of the reactivity...Full Text Available

1970-09-01

105

Locked nucleic acid modified DNA enzymes targeting early growth response-1 inhibit human vascular smooth muscle cell growth

Purpose of reviewThe economic burden due to the sequela of sarcopenia (muscle wasting in the elderly) are staggering and rank similarly to the costs...Full Text Available

2010-05-01

106

Isolation and characterization of cDNA clones for human skeletal muscle alpha actin.

Smooth muscle cell (SMC) proliferation and migration are key processes that occur in the pathogenesis of atherosclerosis and post-angioplasty restenosis. In the present study, we designed locked nucleic...Full Text Available

2004-01-01

107

Huge Psoas Muscle Hematoma due to Lumbar Segmental Vessel Injury Following Percutaneous Endoscopic Lumbar Discectomy

Two cDNA libraries corresponding to polyA+ RNA from human adult skeletal muscle have been constructed by cloning in the PstI site of pBR322. Skeletal alpha actin cDNA clones have been isolated and characterized....Full Text Available

1983-06-11

108

Distribution and threshold expression of the tRNA(Lys) mutation in skeletal muscle of patients with myoclonic epilepsy and ragged-red fibers (MERRF).

We present a case of an acute psoas muscle hematoma following percutaneous endoscopic lumbar discectomy. A 60-year-old female who presented with far lateral lumbar disc herniation underwent endoscopic...Full Text Available

2009-03-01

109

Bilateral enlargement of the orbital muscles: first manifestation of renal adenocarcinoma; Espessamento da musculatura extrinseca orbitaria bilateralmente: manifestacao primaria de adenocarcinoma renal

We investigated the distribution and expression of mutant mtDNAs carrying the A-to-G mutation at position 8344 in the tRNA(Lys) gene in the skeletal muscle of four patients with myoclonus epilepsy and...Full Text Available

1992-12-01

110

31P NMR study of improvement in oxidative phosphorylation by vitamins K3 and C in a patient with a defect in electron transport at complex III in skeletal muscle.

The authors present an unusual case of a patient with orbital metastases from renal carcinoma involving the extra ocular muscles bilaterally. The importance of computed tomography for the differential diagnosis with other orbital lesions is emphasized. (author)

2000-06-01

111

cDNA Cloning and mRNA analysis of PGC-1 in epitrochlearis muscle in swimming-exercised rats.

The bioenergetic capacity of skeletal muscle in a 17-year-old patient with a severe defect in complex III of the electron transport chain has been examined by 31P NMR measurements of the molar ratio...Full Text Available

1984-06-01

112

Prediction of the intramuscular fat content in loin muscle of pig carcasses by quantitative time-resolved ultrasound

Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1), a cold-inducible coactivator of nuclear receptors, stimulates mitochondrial biogenesis and respiration in muscle cells. In the present study, we first cloned a rat PGC-1 gene from a brown adipose tissue cDNA library which encodes a predicted 796-amino-acid protein and exhibits respectively 98% and 95% identity with the mouse and human homologues. Next, we examined the effect of swimming exercise training on the level of expression of the PGC-1 gene in rat epitrochlearis (Epi) muscle. PGC-1 mRNA level in Epi muscle in rats that swam 2 h a day for 3 and 7 days increased dramatically by 154% and 163%, respectively, compared to the non-exercised control group. PGC-1 mRNA up-regulation was not observed in an immersion group treated at 35 degrees C during the training program but without swimming exercise. These results demonstrate that expression of the ...

2000-08-01

113

British Library Electronic Table of Contents (United Kingdom)

A novel method for non-destructive intramuscular fat (IMF) estimation via spectral ultrasound backscatter analysis of signals obtained from pig carcasses early post mortem is described. A commercial hand-held ultrasound device (center frequency: 2.7MHz) was modified to focus the sound beam to the longissimus muscle at the 2nd/3rd last rib. Time-resolved ultrasound backscatter signals of loin muscle were recorded 45minp.m. on 82 pig carcass sides. Backfat width (d"B"F=18.9+/-3.8mm) and muscle attenuation (@a"m"u"s"c"l"e=.77+/-.15dBMHz^-^1cm^-^1) were assessed from the measured pulse echo data. Other propagation properties of skin, backfat and muscle tissue obtained in a previous investigation were incorporated into the signal pre-processing to minimize parameter estimation artifacts. Spectr...

2012-01-01

114

The effect of flow-hole structure and water chemistry on scale adhesion at the leading edge of a flow hole in a heat exchanger

The influence of psychological contracts on the adjustment and organisational commitment among expatriates: An empirical study in Taiwan

In the heat exchangers of power plants, scale deposition may occur, especially at the leading edge of contraction. The growth of scale can lead to an increase in pressure and cause oscillation of the water level. In our previous study, the dependence of flow on contraction geometry was analyzed numerically and empirically. It was shown that the contraction ratio of hydraulic diameter of the flow path contributed greatly to the difference in pressure drop and turbulent kinetic energy at the leading edge of the flow path. In this study, the effect of contraction geometry and flow rate on scale adhesion was studied in AVT chemistry at 270degC using a high-velocity scale-adhesion test loop. The differential pressure and the amount of scale deposited due to scale adhesion at the leading edge of the flow path increased more in a quatrefoil-type flow path than in drill-type flow path. The differential pressure ...

1999-05-01

115

British Library Electronic Table of Contents (United Kingdom)

Purpose - The purpose of this research is to investigate the influence of psychological contracts on the adjustment and organisational commitment of expatriates during international business assignments. The study also aims to investigate the influence of psychological barriers to expatriate adjustment. Design/methodology/approach - A unique survey questionnaire was developed to collect data from 219 Taiwanese business expatriates during the first quarter of 2007. A LISREL analysis is used to test the hypotheses of the research framework. Findings - The study finds that: perceived fulfilment of the psychological contracts of expatriates significantly influences both their adjustment to foreign situations and their organisational commitment; psychological barriers to adjustment have a negat...

2009-01-01

116

Update of the Navy Contract Writing Guide Phase III

Unclas - NASA Technical Report Server (NTRS)

... Defense Finance and Accounting Service DID Data Item Descriptions DLA Defense Logistics Agency DLAM Defense Logistics Agency Manual ...

2005-06-01

117

Technical report templates

COMPUTER PROGRAM GRADE. FOR DESIGN AND ANALYSIS. OF GRADED-POROSITY HEAT-PIPE. WICKS. Contract No. NAS 2-8310. August 1974. Prepared by. J. E. Eninger ...

118

Tear Strength of Elastomers under Threshold Conditions

Performance testing and ...Performance testing and commissioning In either an Authority-owned or a dedicated MRF, the Contracting Authority should ...Performance testing is done to demonstrate that the contractor is able to meet the guarantees given

119

Production engineering measure for capacitors, electrolytic aluminum high reliability, high voltage

... the Naval Research Laboratory (Contract NOOO14-82-K-2015), Cabot Corporation, and Lord Kinematics Division of Lord Corporation. The authors ...

1983-04-01

120

Nerve-Evoked Constriction of Rat Tail Veins Is Potentiated and Venous Diameter Is Reduced after Chronic Spinal Cord Transection

Production engineering measures for improving production techniques to increase the reliability of high voltage, high temperature aluminum electrolytic capacitors have been completed. The required number of capacitors for each contract item were life tested at 85C for 10,000 hours. There were 9,400 capacitors on the extended life test. Reliability for CU13 and CU17 capacitors and contract item 2AG rated 1.5 mfd - 400 V are shown. The verification testing, which was performed at 125 C on 40 capacitors for each contract item, met the requirements of MIL-C-39018A. It further demonstrated that in addition to CU13 styles which are designed to operate at 125 C, the CU17 manufactured for this contract are capable of operating at 125C with derated voltage. Process specifications and Quality Control Manual are included.

1975-07-01

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121

British Library Electronic Table of Contents (United Kingdom)

Abstract Despite reduced sympathetic activity below the level of a spinal cord injury (SCI), venoconstriction during autonomic dysreflexia increases venous return to the heart. Here, contractions of isometrically mounted tail veins from rats with spinal transection at T4 performed 8???10 weeks earlier are compared with those from sham-operated rats. After SCI, lumen diameter was reduced by ?30% and the contractions evoked by electrical stimulation of the perivascular axons were larger than control. This augmentation of neurovascular transmission was not associated with enhanced sensitivity to ?-adrenoceptor agonists or to adenosine-5?-triphosphate (ATP) although contractions to depolarization with K+ were larger after SCI. The percentage reduction in nerve-evoked contraction after SCI prod...

2011-01-01

122

NYA CR-54408 CONTRACT NAS 3-6264 - NASA Technical Reports Server

Incorporation of hyaluronic acid into collagen scaffolds for the control of chondrocyte-mediated contraction and chondrogenesis

It should be noted that computer -grade aluminum electrolytic capacitors. In order to limit the ripple in the source current to 270 (RMS) when the ...

123

DCAA Contract Audit Manual. Volume 2, Chapters 12 - 15 ...

Hyaluronic acid (HA), a principal matrix molecule in many tissues, is present in high amounts in articular cartilage. HA contributes in unique ways to the physical behavior of the tissue, and has been shown to have beneficial effects on chondrocyte activity. The goal of this study was to incorporate graduated amounts of HA into type I collagen scaffolds for the control of chondrocyte-mediated contraction and chondrogenesis in vitro. The results demonstrated that the amount of contraction of HA/collagen scaffolds by adult canine articular chondrocytes increased with the HA content of the scaffolds. The greatest amount of chondrogenesis after two weeks was found in the scaffolds which had undergone the most contraction. HA can play a useful role in adjusting the mechanical behavior of tissue engineering scaffolds and chondrogenesis in chondrocyte-seeded scaffolds.

2007-09-15

124

Container System Hardware Status Report 1990

... Final accounting for extended to include ?mounts applicable ... is verified by the finance or disbursing ... the contractor must claim DLA, contractors must ...

1995-01-01

125

Competition and Innovation in the US Fixed-Wing Military ...

... was released and three prototype contracts were awarded by TACOM on 18 January 1989, to General Motors Corporation, PACCAR, and Osh Kosh ...

2011-05-14

126

Compaction of dust clumps in a protostellar cloud

... Competition ... 4. TITLE AND SUBTITLE Competition and Innovation in the US Fixed-Wing Military Aircraft Industry 5a. CONTRACT NUMBER 5b. ...

2011-05-13

127

Commercial Contract Training, Marine Corps Area VOTEC ...

Necessary conditions are derived for compact aggregates of solid matter to develop from loose local clumps of dust grains in a contracting protostellar cloud.

1984-01-01

128

Center for Innovative Minimally Invasive Therapy (CIMIT)

... Plaster Foundry facings_ Casting: (Non-ferrous Ferrous Alloy .___) Cupola furnace Core baking oven_ _ Metallurgy__ Thermite casting__ ...

1975-06-01

129

CONTRACT: NAS 8-11811 DESIGN, DEVELOPMENT, MANUFACTURE, AND ...

... have been awarded a contract from the Combating Terrorism Technology Support Office Technology Support Working Group (TSWG) of the ...

2004-10-01

130

CONTRACT NASI-20100 - NASA LaRC

has been generally related to magnetic forming. One of the methods suggested was the following: A "pancake" magnetic coil is placed over a thin aluminum ...

131

Atmospheric Scintillation Effects on Electromagnetic Weapons

nclude sick leave, vacation, holiday leave, military leave, or any type. NAS1- 201OO ..... Employees Retirement System (FERS , and the CSRS Offset. Under the ...

132

Protein expression in white spot syndrome virus infected Penaeus monodon fabricius.

... 4. TITLE AND SUBTITLE Atmospheric Scintillation Effects on Electromagnetic Weapons 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. ...

2008-12-01

133

High-mobility group box 1 release and redox regulation accompany regeneration and remodeling of skeletal muscle.

White spot syndrome virus (WSSV) is the causative agent of the white spot disease of shrimp. Penaeus monodon were captured from Muttukadu Estuary in Chennai, India, transported to the laboratory and maintained in an aerated system with continuous water circulation-biofiltration. WSSV-free P. monodon were challenged by feeding them only once with WSSV-infected tissues of P. monodon. Cumulative mortality (100%) of the infected individuals was determined. Tissues from infected and uninfected shrimp such as muscles, hepatopancreas, heart, gills and eye tissues (100mg of each) and haemolymph (50 microl) were subjected to SDS-PAGE. In infected muscle tissue, six newly expressed proteins were detected. In infected haemolymph, four new proteins and three intensely expressed high molecular weight proteins were observed. Three intensely expressed high molecular weight proteins were detected in infected heart tissue and two new proteins in infected ...

2005-06-01

134

Near infrared spectroscopy-derived interstitial hydrogen ion concentration and tissue oxygen saturation during ambulation

Abstract High-mobility group box 1 (HMGB1), a damage-associated molecular pattern (DAMP) molecules, favors tissue regeneration via recruitment and activation of leukocytes and stem cells. Here we demonstrate, in a model of acute sterile muscle injury, that regeneration is accompanied by active reactive oxygen species (ROS) production counterbalanced and overcome by the generation of antioxidant moieties. Mitochondria are initially responsible for ROS formation. However, they undergo rapid disruption with almost complete disappearance. Twenty-four hours after injury, we observed a strong induction of MURF1 and atrogin-1 ubiquitin ligases, key signals in activation of the proteasome system and induction of muscle atrophy. At later time points, ROS generation is maintained by nonmitochondrial sources. The antioxidant response occurs in both regenerating fibers and leukocytes that express high levels of free thiols and antioxidant enzymes, such as ...

2011-05-09

135

British Library Electronic Table of Contents (United Kingdom)

The objective of this study was to determine whether walking and running at different treadmill speeds resulted in different metabolic and cardiovascular responses in the vastus lateralis (VL) and lateral gastrocnemius (LG) by examining metabolite accumulation and tissue oxygen saturation. Ten healthy subjects (6 males, 4 females) completed a submaximal treadmill exercise test, beginning at 3.2?km?h?1 and increasing by 1.6?km?h?1 increments every 3?min until reaching 85% of age-predicted maximal heart rate. Muscle tissue oxygenation (SO2), total hemoglobin (HbT) and interstitial hydrogen ion concentration ([H+]) were calculated from near infrared spectra collected from VL and LG. The [H+] threshold for each muscle was determined using a simultaneous bilinear regression. Muscle and treadmil...

2011-01-01

136

Measurement of attenuation coefficients for bone, muscle, fat and water at 140, 364 and 662keV ?-ray energies

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

The half-value thicknesses, linear and mass attenuation coefficients of biological samples such as bone, muscle, fat and water have been measured at 140, 364 and 662keV ?-ray energies by using the ATOMLABTM-930 medical spectrometer. The ?-rays were obtained from 99mTc, 131I and 137Cs ?-ray point sources. Also theoretical calculations have been performed in order to obtain the half-value thicknesses and, mass and linear attenuation coefficients at photon energies 0.001keV-20MeV for bone, muscle and water samples. The calculated value and the experimental results of this work and the other results in literature are found to be in good agreement.

2006-11-01

137

British Library Electronic Table of Contents (United Kingdom)

Fibroblast growth factor (FGF) signaling has been shown to regulate lung epithelial development but its influence on mesenchymal differentiation has been poorly investigated. To study the role of mesenchymal FGF signaling in the differentiation of the mesenchyme and its impact on epithelial morphogenesis, we took advantage of Fgfr2c+/? mice, which due to a splicing switch express Fgfr2b in mesenchymal tissues and manifest Apert syndrome-like phenotypes. Using a set of in vivo and in vitro studies, we show that an autocrine FGF10?FGFR2b signaling loop is established in the mutant lung mesenchyme, which has several consequences. It prevents the entry of the smooth muscle progenitors into the smooth muscle cell (SMC) lineage and results in reduced fibronectin and elastin deposition. Levels of...

2006-01-01

138

Effect of knee joint cooling on the electromyographic activity of lower extremity muscles during a plyometric exercise

British Library Electronic Table of Contents (United Kingdom)

During sporting events, injured athletes often return to competition after icing because of the reduction in pain. Although some controversy exists, several studies suggest that cryotherapy causes a decrease in muscle activity, which may lead to a higher risk of injury upon return to play. The purpose of this study was to investigate the effect of a 20-min knee joint cryotherapy application on the electromyographic activity of leg muscles during a single-leg drop jump in twenty healthy subjects, randomly assigned to an experimental and a control group. After the pre-tests, a crushed-ice bag was applied to the knee joint of the experimental group subjects for 20min, while the control group subjects rested for 20min. All subjects were retested immediately after this period and retested again...

2010-01-01

139

Comparing the Safety and Efficiency of Conventional Monopolar, Plasmakinetic, and Holmium Laser Transurethral Resection of Primary Non-muscle Invasive Bladder Cancer

British Library Electronic Table of Contents (United Kingdom)

Abstract Purpose: To compare the safety and efficiency of conventional monopolar, plasmakinetic and holmium laser transurethral resection of bladder tumor (CM-TURBT, PK-TURBT and HoL-TURBT) while managing primary non-muscle invasive bladder cancer. Patients and Methods: From 2005 to 2009, 173 patients with primary non-muscle invasive bladder cancer underwent endoscopic surgery. Among them, 51 patients underwent CM-TURBT, 58 patients underwent PK-TURBT, and 64 patients underwent HoL-TURBT. All patients were divided into three risk groups (low, intermediate, and high) based on the European Association of Urology guidelines and prognostic factors of recurrence. Clinical data, included preoperative, operative, and postoperative management and follow-up, were recorded. Results: Patient demograp...

2010-01-01

140

The effect of type I migration on the formation of terrestrial planets in hot-Jupiter systems

On the origin of the Trojan asteroids Effects of Jupiter's mass accretion and radial migration

Context: Our previous models of a giant planet migrating through an inner protoplanet/planetesimal disk find that the giant shepherds a portion of the material it encounters into interior orbits, whilst scattering the rest into external orbits. Scattering tends to dominate, leaving behind abundant material that can accrete into terrestrial planets. Aims: We add to the possible realism of our model by simulating type I migration forces which cause an inward drift, and strong eccentricity and inclination damping of protoplanetary bodies. This extra dissipation might be expected to enhance shepherding at the expense of scattering, possibly modifying our previous conclusions. Methods: We employ an N-body code that is linked to a viscous gas disk algorithm capable of simulating: gas accretion onto the central star; gap formation in the vicinity of the giant planet; type II migration of the giant planet; type I migration of protoplanets; and the effect of gas drag on ...

2007-01-01

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141

Investigation of Heat Transfer in Supercritical Fluids for Application to the Generation IV

We present analytic and numerical results which illustrate the effects of Jupiter's accretion of nebular gas and the planet's radial migration on its Trojan companions. Initially, we approximate the system by the planar circular restricted three-body problem and assume small Trojan libration amplitudes. Employing an adiabatic invariant calculation, we show that Jupiter's thirty-fold growth from a $10 M_\\oplus$ core to its present mass causes the libration amplitudes of Trojan asteroids to shrink by a factor of about 2.5 to $\\sim 40%$ of their original size. The calculation also shows that Jupiter's radial migration has comparatively little effect on the Trojans; inward migration from 6.2 to 5.2 AU causes an increase in Trojan libration amplitudes of $\\sim4%$. In each case, the area enclosed by small tadpole orbits, if made dimensionless by using Jupiter's semimajor axis, is approximately conserved. Similar adiabatic invariant calculations for inclined and ...

2000-01-01

142

Binaries migrating in a gaseous disk: Where are the Galactic center binaries?

Using a facility named SPHINX, which can accommodate a heat transfer test with CO{sub 2} at supercritical pressure, a series of tests was performed. The test geometries include tubes with the inner diameter of 4.4, 6.32 and 9 mm. a concentric annular passages with 8 x 10 mm, and an eccentric annular passages with 9.5 x 12.5 mm. Based on the test results, heat transfer correlations were developed and compared with the existing correlations. The heat transfer deterioration which may occur at certain conditions of heat and mass flux, were carefully studied and the published criteria were reviewed against our test results. Numerical calculation by using commercial CFD code, Fluent, were performed in order to provide the pre-test information for the heat transfer tests. Various turbulence models were evaluated and reliable models were suggested for each case

2007-08-15

143

A ~5 M_earth Super-Earth Orbiting GJ 436?: The Power of Near-Grazing Transits

The massive stars in the Galactic center inner arcsecond share analogous properties with the so-called Hot Jupiters. Most of these young stars have highly eccentric orbits, and were probably not formed in-situ. It has been proposed that these stars acquired their current orbits from the tidal disruption of compact massive binaries scattered toward the proximity of the central supermassive black hole. Assuming a binary star formed in a thin gaseous disk beyond 0.1 pc from the central object, we investigate the relevance of disk-satellite interactions to harden the binding energy of the binary, and to drive its inward migration. A massive, equal-mass binary star is found to become more tightly wound as it migrates inwards toward the central black hole. The migration timescale is very similar to that of a single-star satellite of the same mass. The binary's hardening is caused by the formation of spiral tails lagging the stars inside the binary's Hill radius. We show ...

2010-01-01

144

Implementation guide for Hanford Tanks Initiative C-106 heel retrieval contract management HNF-2511

Most of the presently identified exoplanets have masses similar to that of Jupiter and therefore are assumed to be gaseous objects. With the ever-increasing interest in discovering lower-mass planets, several of the so-called super-Earths (i.e., with masses in the interval 1 M_earth < M < 10 M_earth), which are predicted to be rocky, have already been found. Here we report the possible discovery of a planet around the M-type star GJ 436 with a minimum mass of 4.8+/-0.6 M_earth and a true mass of ~5 M_earth, which makes it the least massive planet around a main-sequence star found to date. In contrast with other discoveries, the planet is identified from its perturbations on an inner Neptune-mass transiting planet (GJ 436b), by pumping eccentricity and producing secular variations in the orbital inclination. Analysis of published radial velocity measurements indeed reveals a significant signal corresponding to an orbital period that is very close to the 2:1 ...

2008-01-01

145

Far East combined-cycle update

This report is an Implementation Guide for Hanford Tanks Initiative C-106 heel retrieval contract management HNF-2511 to provide a set of uniform instructions for managing the two contractors selected. The primary objective is to produce the necessary deliverables and services for the HTI project within schedule and budget.

1998-04-17

146

Exploration and practice on contract management of Daya Bay Nuclear Power Station

Korea Electric Power Corporation (Kepco) of South Korea has awarded Asea Brown Boveri Switzerland, a member of the ABB Group, a contract to supply the main equipment for two gas-fired combined-cycle power stations. News of the contract followed an announcement last year that Kepco will build a series of gas-fired power stations in the early 1990s to supply electricity to new housing and commercial areas being built in the Seoul-Incheon connurbation. (author).

1991-03-01

147

Application of remote sensing for coal waste embankment monitoring

In the market economy, Daya Bay Nuclear Power Station needs to out source or allow to suppliers among industries, while concentrating its core competitive capability, for safely and stable operation. By evaluating the features of contract management in Daya Bay Nuclear Power Station, set up the organization and process of the supply management

2002-02-01

148

misty somites, a maternal effect gene identified by transposon-mediated insertional mutagenesis in zebrafish that is essential for the somite boundary maintenance

The Bureau of Mines has two projects in the remote sensing field as it pertains to mining. One of these is a completed contract that studied the use of aircraft mounted cameras and the results of photogrammetry. The second project is an ongoing contract to study the effectiveness of using an instrumentation system wired to remote data collection station to record embankment data. 6 refs.

1981-01-01

149

[Legionella pneumonia caused by aspiration of hot spring water after sarin exposure].

Somite boundary formation is crucial for segmentation of vertebrate somites and vertebrae and skeletal muscle morphogenesis. Previously, we developed a Tol2 transposon-mediated...Full Text Available

2008-04-15

150

Use of a Cybex NORM dynamometer to assess muscle function in patients with thoracic cancer

A 72-year-old man was exposed to the sarin gas attack in a Tokyo subway on March 20 th, 1995. After exposure, he noticed eye discomfort, chest tightness, headache and weakness of the lower limbs and oropharyngeal muscles. Despite these symptoms, he visited a hot spring on the same day with his family. On March 25 th, his muscle weakness progressed, and a low grade fever appeared. His muscle weakness disappeared 8 days after exposure to sarin, but respiratory failure rapidly developed, necessitating artificial ventilation within four day after hospitalization on March 28th. Chemotherapy with erythromycin, imipenem/cilastatin, and steroid pulse therapy was begu. PCR and culture of sputum collected by bronchofiberscopy were positive for Legionella pneumophila, serogroup I. His respiratory state improved, but subsequent infection with Pseudomonous aeruginosa. Enterobacter cloacae, and Candida tropicalis/glabrata caused his ...

1998-03-01

151

Unloaded Shortening Velocity of Voluntarily and Electrically Activated Human Dorsiflexor Muscles In Vivo

BackgroundThe cachexia-anorexia syndrome impacts on patients' physical independence and quality of life. New treatments are required and need to be evaluated using acceptable and...Full Text Available

152

Ultrabiomicroscopic-Histopathologic Correlations in Individuals with Autosomal Dominant Congenital Microcoria: Three-Generation Family Report

We have previously shown that unloaded shortening velocity (V₀) of human plantar flexors can be determined in vivo, by applying the “slack test”...Full Text Available

153

Transdifferentiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha.

BackgroundCongenital microcoria (CMC) is due to a maldevelopment of the dilator pupillae muscle of the iris, with a pupil diameter of less than 2 mm. It is associated with juvenile...Full Text Available

154

Toxic Myopathy in a Dog Associated with the Presence of Monensin in Dry Food

Skeletal muscle and adipose tissue development often has a reciprocal relationship in vivo, particularly in myodystrophic states. We have investigated whether determined myoblasts with no inherent adipogenic...Full Text Available

1995-10-10

155

The reactivity of thiol groups and the subunit structure of aldolase

This report describes a case of toxic myopathy in a two year old sheltie dog with clinical signs of profound weakness, myoglobinuria, and muscle enzyme elevations. The clinical signs were likely related...Full Text Available

1980-01-01

156

The comparative structure of mammalian glyceraldehyde 3-phosphate dehydrogenase

1. Seven unique carboxymethylcysteine-containing peptides have been isolated from tryptic digests of rabbit muscle aldolase carboxymethylated with iodo[2-¹⁴C]acetic acid in 8m-urea....Full Text Available

1970-04-01

157

The Gross Morphology and Histochemistry of Respiratory Muscles in Bottlenose Dolphins, Tursiops truncatus

1. The amino acid sequences around the thiol groups of glyceraldehyde 3-phosphate dehydrogenase from badger and monkey skeletal muscle were compared with the sequences around the thiol groups in the...Full Text Available

1969-01-01

158

The Effect of Graded Recession and Anteriorization on Unilateral Superior Oblique Palsy

Most mammals possess stamina because their locomotor and respiratory (i.e., ventilatory) systems are mechanically coupled. These systems are decoupled, however, in bottlenose dolphins (Tursiops...Full Text Available

2008-12-01

159

The Dystrophin Complex Controls BK Channel Localization and Muscle Activity in Caenorhabditis elegans

PurposeWe wanted to examine the effect of graded recession and anteriorization of the inferior oblique muscle on patients suffering from unilateral superior oblique palsy.MethodsInferior...Full Text Available

2006-09-01

160

Test-retest reliability of knee kinesthesia in healthy adults

Genetic defects in the dystrophin-associated protein complex (DAPC) are responsible for a variety of pathological conditions including muscular dystrophy, cardiomyopathy, and vasospasm. Conserved DAPC...Full Text Available

2009-12-01

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161

Soluble Epoxide Hydrolase as a Therapeutic Target for Cardiovascular Diseases

BackgroundSensory information from mechanoreceptors in the skin, muscles, tendons, and joint structures plays an important role in joint stability. A joint injury can lead to disruption...Full Text Available

162

Progressive Management of Open Surgical Repair of Achilles Tendon Rupture

PrefaceCardiovascular effects of epoxyeicosatrienoic acids (EETs) include vasodilation, vascular smooth muscle cell anti-migratory actions, and anti-inflammatory actions. These...Full Text Available

2009-10-01

163

Poland's anomaly. Natural history and long-term results of chest wall reconstruction in 33 patients.

A 33-year-old man sustained an acute Achilles tendon rupture which was surgically repaired. Early nonweight-bearing range of motion and strengthening of the ankle and the repaired muscle unit was allowed...Full Text Available

1994-12-01

164

Phosphorylation-dependent power output of transgenic flies: an integrated study.

Poland's anomaly is an uncommon congenital aberration of the chest wall characterized by absence of the pectoralis major muscle and other nearby musculoskeletal components. In this series, a wide spectrum...Full Text Available

1988-12-01

165

Osteoid osteoma near the intervertebral foramen may induce radiculopathy through tumorous inflammation

We examine how the structure and function of indirect flight muscle (IFM) and the entire flight system of Drosophila melanogaster are affected by phosphorylation of the myosin regulatory light chain...Full Text Available

1997-12-01

166

Near-infrared spectroscopy technique to evaluate the effects of red blood cell transfusion on tissue oxygenation

Osteoid osteoma of the spine is a relatively rare bone-forming tumor. Pain that is worse at night and relieved by aspirin and muscle contracture are the most characteristic symptoms of spinal osteoid...Full Text Available

167

NOTCH3 expression is induced in mural cells through an autoregulatory loop that requires endothelial-expressed JAGGED1

IntroductionThe aim of this study was to evaluate the effects of red blood cell (RBC) transfusions on muscle tissue oxygenation, oxygen metabolism and microvascular reactivity in...Full Text Available

2009-01-01

168

Modular control of human walking: Adaptations to altered mechanical demands

Endothelial cells and mural cells (smooth muscle cells, pericytes, or fibroblasts) are known to communicate with one another. Their interactions not only serve to support fully functional blood...Full Text Available

2009-02-27

169

Modelling the masticatory biomechanics of a pig

Studies have shown that the nervous system may adopt a control scheme in which synergistic muscle groups are controlled by common excitation patters, or modules, to simplify the coordination...Full Text Available

2010-02-10

170

Mechanism of Catch Force: Tethering of Thick and Thin Filaments by Twitchin

The relationships between muscle tensions, jaw motions, bite and joint forces, and craniofacial morphology are not fully understood. Three-dimensional (3-D) computer models are able to combine anatomical...Full Text Available

2002-11-01

171

Lower trunk kinematics and muscle activity during different types of tennis serves

Catch is a mechanical state occurring in some invertebrate smooth muscles characterized by high force maintenance and resistance to stretch during extremely slow relaxation. During catch, intracellular...Full Text Available

2010-01-01

172

Late onset muscle plasticity in the whisker pad of enucleated rats

BackgroundTo better understand the underlying mechanisms involved in trunk motion during a tennis serve, this study aimed to examine the (1) relative motion of the middle and lower...Full Text Available

173

Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na⁺ channels enhancing the antimyotonic activity in vivo

Blindness leads to a major reorganization of neural pathways associated with touch. Because incoming somatosensory information influences motor output, it is plausible that motor plasticity occurs in...Full Text Available

2008-10-14

174

Increased endothelial and vascular smooth muscle cell adhesion on nanostructured titanium and CoCrMo

Searching for the structural requirements improving the potency and the stereoselectivity of Na⁺ channel blockers as antimyotonic agents, new...Full Text Available

2001-12-01

175

ICC-MY coordinate smooth muscle electrical and mechanical activity in the murine small intestine

In the body, vascular cells continuously interact with tissues that possess nanostructured surface features due to the presence of proteins (such as collagen and elastin) embedded in the vascular wall....Full Text Available

2006-03-01

176

Human mitochondrial transcription factor A reduction and mitochondrial dysfunction in Hashimoto's hypothyroid myopathy.

BackgroundAnimals carrying genetic mutations have provided powerful insights into the role of interstitial cells of Cajal (ICC) in motility. One classic model is...Full Text Available

2010-05-01

177

Handgrip dynamometry, Cybex measurements and lean mass as markers of the ageing of muscle function.

BACKGROUND: Mitochondrial changes have been described in muscle tissue in acquired hypothyroidism. Among the molecular mechanisms by which thyroid hormones regulate expression of nuclear genes encoding...Full Text Available

2002-06-01

178

Force enhancement without changes in cross-bridge turnover kinetics: the effect of EMD 57033.

Isometric handgrip force, isokinetic knee flexion and extension torque, and anthropometric data were obtained on 67 older men and women (ranging in age from 45 to 75 years, mean 59.7 years). Hydrostatic...Full Text Available

1991-12-01

179

Effects of rest interval on isokinetic strength and functional performance after short-term high intensity training.

The thiadiazinon derivative EMD 57033 has been found previously in cardiac muscle to increase isometric force generation without a proportional increase in fiber ATPase, thus causing a reduction in...Full Text Available

1997-01-01

180

EFFECT OF AGE ON THE ROLE OF RHO-KINASE IN SHORT TERM PARTIAL BLADDER OUTLET OBSTRUCTION

OBJECTIVES: The ability to maximally generate active muscle tension during resistance training has been established to be a primary determinant for strength development. The influence of intrasession...Full Text Available

1997-09-01

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181

Differential Regulation of PDE5 Expression in Left and Right Ventricles of Feline Hypertrophy Models

ObjectivesWe examined the expression of Rho Kinase (ROK) isoforms in young and old rabbit’s detrusor smooth muscles (SM) during the progression of short term...Full Text Available

2008-03-01

182

Creatine and Phosphocreatine: A Review of Their Use in Exercise and Sport

BackgroundThough long known to affect smooth muscle biology, recent studies indicate that phosphodiesterase 5 (PDE5) is also expressed in myocardium. Recognizing that the regulation...Full Text Available

183

Canine Malignant Hyperthermia: Diagnosis of Susceptibility in a Breeding Colony

Objective: Creatine and phosphocreatine (PCr) are important compounds in the normal energy metabolism of muscle. Recently, it has been shown that dietary creatine (5 to 20 g/day)...Full Text Available

1997-01-01

184

Aberrant repair and fibrosis development in skeletal muscle

Fifteen related dogs were studied for susceptibility to malignant hyperthermia using halothane challenge and caffeine contracture tests. These dogs had hypertrophied muscles, were of a nervous temperament...Full Text Available

1983-06-01

185

ATP overflow in skeletal muscle 1A arterioles

The repair process of damaged tissue involves the coordinated activities of several cell types in response to local and systemic signals. Following acute tissue injury, infiltrating inflammatory cells...Full Text Available

186

A School-Based Exercise Intervention Program Increases Muscle Strength in Prepubertal Boys

The purpose of this study was to investigate the sources of ATP in the 1A arteriole, and to investigate age-related changes in ATP overflow. Arterioles (1A) from the red portion of the gastrocnemius...Full Text Available

2010-08-15

187

Total mercury and its distribution in blue crab and deep water pink shrimp from Alexandria coast.

This prospective controlled intervention study over 12 months evaluated the effect of exercise on muscular function, physical ability, and body composition in pre-pubertal boys. Sixty-eight boys aged...Full Text Available

2010-01-01

188

Influence of UMTS mobile phone microwave fields on the muscular system; Einfluss von Mikrowellenfeldern des UMTS Mobilfunks auf das muskulaere System

Total mercury content and its distribution in muscles and viscera of male and female blue crab (Callinectes sapidus Rothbum) and deep water pink shrimp (Parapenacus longirostris) collected from the 3 main fishing grounds near the Alexandria coast in the Mediterranean sea was estimated. The results indicate that the mercury content in the muscles of both species differ according to fishing areas, size, sex, and species. More than 75% of total mercury were accumulated in the viscera of both species which indicates that the mercury entered in these organisms via the feed chain. PMID:3696196

1987-01-01

189

Improvement of muscle strenght independently of analgesic effect following spinal cord stimulation. A case report.

Two hypotheses are in the centre of this investigation, on the one hand the question, whether microwaves as exogenous fields alone are able to stimulate human muscle cells above-threshold, and on the other hand, whether microwaves as conditioning to cathodical electrical pulses can modify the excitation threshold and form. No excitation through the application of microwaves alone can be introduced at any subject. The conditioning of above-threshold cathodical electrical pulses with UMTS-microwaves leads not to a transgression of the threshold or the electrical muscle response (EMG) depending on the amplitude, the duration or the dose rate. (orig.)

2004-07-01

190

Mercury and other trace elements in a pelagic Arctic marine food web (Northwater Polynya, Baffin Bay)

Spinal cord stimulation (SCS) is frequently used for relief of chronic benign pain resistant to conservative therapies. Clinical practice suggests, at least in patients with failed back surgery syndrome (FBSS), the possibility that SCS significantly improves motor performances. We present here the case of a 41-years-old female patient with FBSS, who showed a clear improvement in muscle strength after SCS, persisting at 6-months follow-up. We speculate that the electrical stimulation of posterior columns could potentiate the caudal, segmental spinal reflexes resulting in a facilitation of motoneurons activation. PMID:16175150

2004-12-01

191

Mercury and other trace elements in a pelagic Arctic marine food web (Northwater Polynya, Baffin Bay)

Total mercury (THg), methylmercury (MeHg) and 22 other trace elements were measured in ice algae, three species of zooplankton, mixed zooplankton samples, Arctic cod (Boreogadus saida), ringed seals (Phoca hispida) and eight species of seabirds to examine the trophodynamics of these metals in an Arctic marine food web. All samples were collected in 1998 in the Northwater Polynya (NOW) located between Ellesmere Island and Greenland in Baffin Bay. THg and MeHg were found to biomagnify through the NOW food web, based on significant positive relationships between log THg and log MeHg concentrations vs. {delta} {sup 15}N muscle and liver . The slope of these relationships for muscle THg and MeHg concentrations (slope = 0.197 and 0.223, respectively) were similar to those reported for other aquatic food webs. The food web behavior of THg and {delta} {sup 15}N appears constant, regardless of trophic state (eutrophic vs. oligotrophic), latitude (Arctic ...

2005-12-01

192

The relationships of organizational justice, social exchange, psychological contract, and expatriate adjustment: an example of Taiwanese business expatriates

Total mercury (THg), methylmercury (MeHg) and 22 other trace elements were measured in ice algae, three species of zooplankton, mixed zooplankton samples, Arctic cod (Boreogadus saida), ringed seals (Phoca hispida) and eight species of seabirds to examine the trophodynamics of these metals in an Arctic marine food web. All samples were collected in 1998 in the Northwater Polynya (NOW) located between Ellesmere Island and Greenland in Baffin Bay. THg and MeHg were found to biomagnify through the NOW food web, based on significant positive relationships between log THg and log MeHg concentrations vs. #delta# "1"5N muscle and liver . The slope of these relationships for muscle THg and MeHg concentrations (slope = 0.197 and 0.223, respectively) were similar to those reported for other aquatic food webs. The food web behavior of THg and #delta# "1"5N appears constant, regardless of trophic state (eutrophic vs. oligotrophic), latitude (Arctic vs. ...

2005-12-01

193

British Library Electronic Table of Contents (United Kingdom)

In the field of international human resource management, studies have seldom examined organizational justice, social exchange, and psychological contract together as important factors in influencing the expatriate adjustment process. The purpose of this research is to fill the research gap by examining these factors and their relationships with expatriate adjustment. The researcher conducted a survey of Taiwanese business expatriates during the first quarter of 2007, collecting 219 valid samples for analysis. A hierarchical regression model was used to test the research framework hypotheses, which showed that expatriates' perception of organizational justice has a positive influence both on their perceptions of social exchange and on their psychological contract fulfillment. Expatriates' p...

2010-01-01

194

IAEA RESEARCH CONTRACTS FIRST ANNUAL REPORT. Technical reports Series No. 4

Summaries are included of research contracts which expired prior to Dec. 31, 1960. The contracts were concerned with investigations of: electrophysiological responses of biological systems in nerve cells to irradiation with small doses of ionizing radiations; the mode of the protective action of certain sulfhydryl compounds against radiation effects on the synthesis of deoxyribonucleic acid, using tritium-labeled thymidine; development of a bubble chamber method of monitoring and dosimetry for Low fast neutron fluxes; effects of incorporated radioisotopes on the stability of genetic materials; interrelation of root and leaf absorption of radioisotopes in herbaceous plants; uptake of radioactive wastes by lowland rice from soils contaminated by irrigation water, and decontamination of the rice; and comparison between mutation rates induced by acute and chronic gamma irradiations. (B.O.G.)

1961-01-01

195

Z-Plasty Made Simple

W sub infinity gravity and super- W sub infinity gravity

A Z-plasty is a critical and reliable technique that is useful for scar revisions and correction of free margin distortion. A Z-plasty can help lengthen a contracted scar, change the direction of a...Full Text Available

2010-01-01

196

Uridine adenosine tetraphosphate induces contraction and relaxation in rat aorta

In this paper, the authors construct gauge theories of the W {sub {infinity}} algebra and its super-extension, and discuss their relation to earlier results for the gauging of the classical contraction to the w {sub {infinity}} algebra.

1991-09-30

197

Study on effectiveness of transfusion program in thalassemia major patients receiving multiple blood transfusions at a transfusion centre in Western India

Uridine adenosine tetraphosphate (Up₄A) has been recently reported as an endothelium-derived vasoconstrictor and plasma levels of this dinucleotide are increased in juvenile hypertensive...Full Text Available

2008-01-01

198

Roller Bearing Hot Box Sensor.

Background:Children suffering from beta-thalassemia major require repeated blood transfusions which may be associated with dangers like iron overload and contraction of...Full Text Available

2010-07-01

199

Proposal to negotiate an amendment to an existing contract for the supply of thick 6 inch silicon micro-strip sensors for the CMS tracker

A roller bearing hot box sensor utilizing a metallic temperature sensitive elongated wire element. The wire element contacts at temperatures in the range of about 125 F to about 225 F so that when the contraction movement of the wire is attached to a conn...

1982-01-01

200

Plasma Treatment of Surfaces and Plasma Enhanced Deposition.

This document concerns the proposal to negotiate an amendment to an existing contract for the supply of thick 6 inch silicon micro-strip sensors for the CMS tracker. For the reasons explained in this document, the Finance Committee is invited to approve an amendment to an existing contract with HAMAMATSU PHOTONICS (CH) for the supply of 7 000 thick 6 inch silicon micro-strip sensors for the CMS tracker, for an amount of 3 248 000 euros (5 131 840 Swiss francs), not subject to revision, with an option for up to 11 000 additional sensors, for a maximum amount of 4 708 000 euros (7 438 640 Swiss francs), not subject to revision, bringing the total maximum amount of the amendment to 7 956 000 euros (12 570 480 Swiss francs) not subject to revision. This total maximum amount will be added to the initial contract amount of 415 835 000 Japanese yen (4 879 824 Swiss francs), not subject to revision. The amounts in Swiss francs have ...

2004-01-01

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201

Performance Evaluation of the ONR Axial Waterjet 2 (AxWJ-2)

This report results from a contract tasking Eindhoven University of Technology as follows: The contractor will investigate the plasma treatment of surfaces and plasma enhanced deposition using EUT's cascade arc source as the basis for this effort.

1997-01-01

202

... Waterjet 2 (AxWJ-2) by ... 4. TITLE AND SUBTITLE Performance Evaluation of the ONR Axial Waterjet 2 (AxWJ-2) 5a. CONTRACT NUMBER 5b. ...

2009-12-01

203

Observatory reports

Myosin II transport, organization, and phosphorylation: evidence for cortical flow/solation-contraction coupling during cytokinesis and cell locomotion.

This review covers research done at Lawrence Livermore National Laboratory under DOE contract. Areas of research are as follows: star evolution supernovae, and nucleosynthesis; stellar atmospheres and winds; galaxies and interstellar space; and high-energy astrophysics.

1983-01-01

204

The mechanism of cytokinesis has been difficult to define because of the short duration and the temporal-spatial dynamics involved in the formation, activation, force production, and disappearance of...Full Text Available

1996-08-01

205

LAW ON WASTE MANAGEMENT

1 to the operator of a waste collective system by an agreement or contract. The conditions for the ...Fees of the waste collective system are subject to the supervision of the authority responsible for market surveillance. ...The operator of waste collection system collects wastes from producers and holder and transports these to a collection

206

I I I I I I I I I

High Speed Cylindrical Roller Bearing Development.

"MAGNETIC FORMING COIL. DESIGN AND DEVELOPMENT". Contract NAS 8 -5434. SUA4MARY R E PORT. Prepared for. GEORGE C. MARSHALL SPACE FLIGHT CENTER ...

207

Glossary of Commercial and Trade Law Terms (Komerclikumu Un Tirdzniecibas Terminu Vardnica) English/Latvian - Latvian/English.

High speed experimental tests provided data on six parametric cylindrical roller bearings. Four bearing variables were evaluated and the results were correlated with the analytical model developed under Naval Air Propulsion Center Contract N00140-76-C-038...

1980-01-01

208

Glossary of Commercial and Trade Law Terms (Kaubandus-ja Ariseaduse Oskussonastik). English/Estonian - Estonian/English.

The definitions provided in this bilingual glossary are intended to serve as indicative explanations of the defined words and phrases, and not for purposes of interpreting any particular contract or international agreement. Approximately 100 terms appear ...

1995-01-01

209

Glossary of Commercial and Trade Law Terms (Glosar de Termeni de Drept Comercial). English/Romanian - Romanian/English.

The definitions provided in this bilingual glossary are intended to serve as indicative explanations of the defined words and phrases and not for purposes of interpreting any particular contract or international agreement. Approximately 100 terms appear w...

1995-01-01

210

Genome-wide linkage scan for contraction velocity characteristics of knee musculature in the Leuven Genes for Muscular Strength Study

The definitions provided in this bilingual glossary are intended to serve as indicative explanations of the defined words and phrases, and not for purposes of interpreting any particular contract or international agreement. Approximately 100 terms appear ...

1995-01-01

211

Expansions, contractions, and fragility of the spinocerebellar ataxia type 10 pentanucleotide repeat in yeast

The torque-velocity relationship is known to be affected by ageing, decreasing its protective role in the prevention of falls. Interindividual variability in this torque-velocity relationship is partly...Full Text Available

2008-09-01

212

Energy Performance Contracting for New Buildings

Spinocerebellar ataxia 10 (SCA10) is an autosomal dominant disease caused by large-scale expansions of the (ATTCT)_n repeat within an intron of the human ATXN10 gene. In contrast...Full Text Available

2011-02-15

213

Efficacy of ultrasound-guided obturator nerve block in transurethral surgery

situ by isolating portions of the building envelope and performing tests .MAXIMUM ALLOWED LOAD ...and shall identify commissioning team members who will perform testing and prepare documentation.The commissioning agent may be

214

DOD (Department of Defense) Acquisition: Case Study of the MILSTAR (Military Strategic and Tactical Relay) Satellite Communications System.

Background:During transurethral resection surgery (TUR), accidental stimulation of the obturator nerve can cause violent adductor contraction, leading to serious intraoperative...Full Text Available

2011-01-01

215

Cupola Furnace: Machine-Readable Bibliographic Data Base.

The study of the Military Strategic and Tactical Relay (MILSTAR) program focuses on the role of the program manager and contracting officer in developing the acquisition strategy.

1986-01-01

216

Cooperative research in coal liquefaction

One of the tasks comprising ERDA Contract EY-76-S-02-2840, ''Minimization of Cupola Energy and Air Pollution,'' has been the carrying out of a comprehensive survey of world literature relating to the cupola furnace for melting of cast iron. It was decided...

1978-01-01

217

Contraction of the deuteron cluster in /sup 6/Li

Significant progress was made in the May 1990--May 1991 contract period in three primary coal liquefaction research areas: catalysis, structure-reactivity studies, and novel liquefaction processes. A brief summary of the accomplishments in the past year in each of these areas is given.

1991-05-28

218

Coal liquefaction. Quarterly report, July-September 1978

The dependence of the rms radius of the deuteron cluster in /sup 6/Li on the relative d-..cap alpha.. momentum was investigated on the basis of the three-body wave function given by Rai, Lehman, and Ghovanlou.

1981-05-01

219

Chemical refining of coal (Report on ECSC contract 7220-EC/816)

DOE is supporting the development of several conversion processes that are currently in the pilot plant stage. Each of these processes is described briefly and information given as to contractor, contract, funding, site and current progress. Several support projects are treated similarly. (LTN)

1979-05-01

220

Chaperonin Containing T-Complex Polypeptide Subunit Eta (CCT-eta) Is a Specific Regulator of Fibroblast Motility and Contractility

Three areas have been investigated: coal liquefaction with supercritical fluids, liquefaction by extraction with high boiling liquid solvents, and the production of resins from coal-derived hydrocarbons. The processes are described.

1983-01-01

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221

A possible role of decreased relaxation mediated by beta-adrenoceptors in bladder outlet obstruction by benign prostatic hyperplasia.

Integumentary wounds in mammalian fetuses heal without scar; this scarless wound healing is intrinsic to fetal tissues and is notable for absence of the contraction seen in postnatal (adult) wounds....Full Text Available

222

Neuromuscular effects of candoxin, a novel toxin from the venom of the Malayan krait (Bungarus candidus).

1. To explore mechanisms of urinary obstruction in benign prostatic hyperplasia (BPH), the features of contraction and relaxation in human hyperplastic and non-hyperplastic (control) prostatic tissues...Full Text Available

1992-11-01

223

1 Candoxin (MW 7334.6), a novel toxin isolated from the venom of the Malayan krait Bungarus candidus, belongs to the poorly characterized subfamily of nonconventional three-finger toxins present in Elapid venoms. The current study details the pharmacological effects of candoxin at the neuromuscular junction. 2 Candoxin produces a novel pattern of neuromuscular blockade in isolated nerve-muscle preparations and the tibialis anterior muscle of anaesthetized rats. In contrast to the virtually irreversible postsynaptic neuromuscular blockade produced by curaremimetic alpha-neurotoxins, the neuromuscular blockade produced by candoxin was rapidly and completely reversed by washing or by the addition of the anticholinesterase neostigmine. 3 Candoxin also produced significant train-of-four fade during the onset of and recovery from neuromuscular blockade, both, in vitro and in vivo. The fade phenomenon has been attributed to a blockade of putative ...

2003-06-01

224

HEALTH INFO SANTE

Contract pricing of electric and telephone service: Current practice and policy

Information from the CHIS Board and Personnel Division:A new contract to manage our health insurance has been signed with AUSTRIA and it will come into force on 1 January 2000.The changeover to the new contract will not affect those covered by thescheme since there will be no change in the list of services reimbursed or in the reimbursement procedure.However, you are requested (as far as possible) to submit separate claims fortreatment (not bills) received before 1 January 2000 as opposed to treatment received after 1 January 2000. This will help AUSTRIA with its accounting.

1999-01-01

225

Bechtel Hanford Inc. Network Security Plan for the EnvironmentalRestoration Contract

Due mainly to competitive pressures, the practice of offering electric and telephone service under contracts or special tariffs negotiated individually between a utility and its customers has increased in importance in recent years. Moreover, the practice is likely to become still more widespread in the future. This creates questions of public policy that are of interest to regulators and ratepayers alike such as how to supervise the practice, how to encourage utilities to compete while preventing cross-subsidization and anticompetitive behavior, and how the practice will ultimately affect utilities and ratepayers. This report sheds light on the topic by describing approaches that have been taken by the various regulatory commissions and by providing a framework for analyzing such contractors.

1992-04-01

226

X-radiation effects on muscle cell membrane electrical parameters

'As part of the Computer Protection Plan, this Network Security Plan identifies the specific security measures used to protect Bechtel Hanford, Inc.'s (BHI's) enterprise network. The network consists of the communication infrastructure and information systems used by BHI to perform work related to the Environmental Restoration Contract (ERC) at the Hanford Site. It provides electronic communication between the ERC-leased facilities in Richland, Washington, and facilities located on the Hanford Site. Network gateways to other site and offsite networks provide electronic communication with the remainder of the Hanford community.'

1999-06-30

227

Use of Hanford waste water ponds by waterfowl

Early effects of 100 Kilorads of X-rays on muscle cell membrane properties have been measured in sartorius muscles from Leptodactylus ocellatus. Threshold strength for rectangular current pulses increased 10% after irradiation, and action potential propagation velocity decreased 10%. Passive membrane parameters were calculated from potential responses to sub-threshold current pulses, assuming conventional cable theory. Specific membrane conductance increased to 18% after irradiation, membrane capacitance increased 14%, and length constant decreased 10% but membrane time constant was unchanged. Cell diameter decreased 5%, and resting membrane potential decreased 8%. Membrane parameters during an action potential were also evaluated by the phase-plane and current-voltage plot techniques. Irradiation significantly decreased the action potential amplitude, the excitation potential, and the maximum rates of rise and fall of membrane potential. ...

228

Subcellular distribution of ryanodine receptors in the cardiac muscle of carp (Cyprinus carpio).

Census and environmental surveillance information on waterfowl that use the Hanford Site 200 Area waste water ponds are described and evaluated. Physical features of the ponds are discussed in relation to their use and suitability for waterfowl. Seasonal distributions observed for the years 1971 through 1974 indicate that the highest use by waterfowl occurs during the spring and fall migratory periods. Base population estimates are 300 to 400 resident waterfowl with a few tens of pairs nesting during the summer. Environmental surveillance data on "1"3"7Cs in muscle tissue are presented for the years 1971 through 1977. Comparisons are made between Columbia River and waste water pond waterfowl, between waterfowl groups, and among ponds. Waterfowl collected from ponds frequently have easily detected levels of "1"3"7Cs in muscle tissue. However, those waterfowl collected from the Columbia River seldom show a "1"3"7Cs level above that expected from ...

1979-05-01

229

Purification and partial characterization of glycosaminoglycans and proteoglycans from cultured rabbit smooth muscle cells

We examined the subcellular localization of ryanodine receptors (RyR) in the cardiac muscle of carp using biochemical, immunohistochemical, and electron microscopic methods and compared it with those of rats and guinea pigs. To achieve this goal, an anti-RyR antibody was newly raised against a synthetic peptide corresponding to an amino acid sequence that was conserved among all sequenced RyRs. Western blot analysis using this antibody detected a single RyR band following the SDS-PAGE of sarcoplasmic reticulum (SR) membranes from carp atrium and ventricle as well as from mammalian hearts and skeletal muscles. The carp heart band had slightly greater mobility than those of mammalian hearts. Although immunohistochemical staining showed evident striations corresponding to the Z lines in longitudinal sections of mammalian hearts, clusters of punctate staining, in contrast, were distributed ubiquitously throughout carp atrium and ventricle. Electron ...

2003-06-12

230

Multiscale modeling of skeletal muscle properties and experimental validations in isometric conditions.

Glycosaminoglycans synthesized by cultured rabbit smooth muscle cells were isolated after incorporation of (/sup 3/H)-glucosamine into glycosaminoglycans in the presence or absence of 10% fetal bovine serum. Glycosaminoglycans were quantitated by two-dimensional electrophoresis after proteolytic digestion of the cell layers and media. The results show that the presence of serum has no effect on the chondroitin sulfate, heparan sulfate and dermatan sulfate content of the cell layers. The incorporation of (/sup 3/H)-glucosamine into hyaluronic acid of the cell layers was three times higher in the presence of serum. In the medium , the quantity of hyaluronic was two times higher in the presence of serum while the other glycosaminoglycans remained unchanged. The incorporation of (/sup 3/H)-glucosamine into hyaluronic acid was unaffected by the presence of serum. Specific proteoglycans were isolated from medium after with (/sup 35/S)-sulfate and (/sup 3/H)-serine by ...

1985-01-01

231

Anti-muscarinic actions of mitoxantrone in isolated heart muscles of guinea pigs.

In this article, we describe an approach to model the electromechanical behavior of the skeletal muscle based on the Huxley formulation. We propose a model that complies with a well established macroscopic behavior of striated muscles where force-length, force-velocity, and Mirsky-Parmley properties are taken into account. These properties are introduced at the microscopic scale and related to a tentative explanation of the phenomena. The method used integrates behavior ranging from the microscopic to the macroscopic scale, and allows the computation of the dynamics of the output force and stiffness controlled by EMG or stimulation parameters. The model can thus be used to simulate and carry out research to develop control strategies using electrical stimulation in the context of rehabilitation. Finally, through animal experiments, we estimated model parameters using a Sigma Point Kalman Filtering technique and dedicated experimental protocols ...

2011-07-15

232

Thulium laser resection via a flexible cystoscope for recurrent non-muscle-invasive bladder cancer: initial clinical experience

A hypotheses that mitoxantrone is a competitive antagonist at muscarinic cholinergic receptors was examined in guinea-pig hearts. In isolated left atrial muscle preparations, electrically paced at 2 Hz, the muscarinic agonist, carbachol, caused a concentration-dependent decrease in developed tension. Mitoxantrone caused a parallel right-ward shift of the concentration-response curve for carbachol. Schild plots for the effect of mitoxantrone on the carbachol concentration-response relationship were linear with a slope of 0.88 which was not significantly different from the unity. The right-ward shift of the carbachol concentration-response relationship by mitoxantrone significantly reversed after an additional incubation with a mitoxantrone-free solution, although the reversal was incomplete after a 2-h incubation in the mitoxantrone-free solution. Mitoxantrone caused a concentration-dependent displacement of specific [3H]quinuclidinyl benzilate binding to membrane ...

2000-10-27

233

British Library Electronic Table of Contents (United Kingdom)

OBJECTIVE To present our initial experience of thulium laser resection via a flexible cystoscope for recurrent non-muscle-invasive bladder cancer (ThuRBT), as transurethral resection for bladder tumour (TURBT) is regarded as the reference standard for treating this disease, but alternative laser resection or ablation is suitable especially for recurrent tumours. PATIENTS AND METHODS From January 2005 to October 2005, 32 patients with early recurrent bladder tumour (recurrent within a year after TURBT) were treated with ThuRBT via a flexible cystoscope. The follow-up included urine analysis, ultrasonography and cystoscopy every 3 months. RESULTS All patients were treated successfully with ThuRBT in one session, with no bladder haemorrhage, obturator nerve reflex or vesicle perforation. Rand...

2008-01-01

234

Measurement properties of the pressure biofeedback unit in the evaluation of transversus abdominis muscle activity: a systematic review

British Library Electronic Table of Contents (United Kingdom)

Background: Measurements from pressure biofeedback units (PBUs) can be used to evaluate the activity of the transversus abdominis (TrA) muscle indirectly. These measurements can classify patients or monitor the progress of treatment programmes for people with low back pain. Objective: To systematically review studies on the measurement properties of PBUs for the assessment of TrA activity. Data sources: Eligible studies were identified through searches of PUBMED, CINAHL and BIREME (1990 to 2009). In addition, hand searches of journals and citation tracking were performed. Study selection: Full-text studies involving any type of clinimetric tests of PBU measurement for the assessment of TrA activity were selected. Data extraction: Two independent reviewers selected the studies, extracted th...

2011-01-01

235

Kinesiological surface electromyography in normal children: Range of normal activity and pattern analysis

British Library Electronic Table of Contents (United Kingdom)

To document the range of activity and patterns of normal surface kinesiological electromyography in normal children, 87 children ranging from age 3 to 18 years who were developing normally were evaluated at free walking speed. Analysis was performed on 6307 gait cycles from 11 different muscles with custom software. We devised an algorithm to do a computer-based KEMG curve pattern analysis to sort out curves that did not match the physiologic muscle activity pattern, We also devised a combined preset amplitude and statistics-based criteria to satisfactorily determine the onset/cessation of KEMG activity. The measurements of timing and duration of activity, body height and weight, body mass index, cadence, stride length, and age were obtained for statistical analysis. From the pattern recog...

2007-01-01

236

Intravascular pressure augments cerebral arterial constriction by inducing voltage insensitive Ca2+ waves

British Library Electronic Table of Contents (United Kingdom)

This study examined whether elevated intravascular pressure stimulates asynchronous Ca2+ waves in cerebral arterial smooth muscle cells and if their generation contributes to myogenic tone development. The endothelium was removed from rat cerebral arteries, which were then mounted in an arteriograph, pressurized (20 100 mmHg) and examined under a variety of experimental conditions. Diameter and membrane potential (VM) were monitored using conventional techniques; Ca2+ wave generation and myosin light chain (MLC20)/MYPT1 (myosin phosphatase targeting subunit) phosphorylation were assessed by confocal microscopy and Western blot analysis, respectively. Elevating intravascular pressure increased the proportion of smooth muscle cells firing asynchronous Ca2+ waves as well as event frequency. C...

2010-01-01

237

Cytoplasmic p63 immunohistochemistry is a useful marker for muscle differentiation: an immunohistochemical and immunoelectron microscopic study

British Library Electronic Table of Contents (United Kingdom)

TP63, a member of the TP53 gene family, is a nuclear marker of myoepithelial cells. Antibody against p63 is frequently used to aid in the diagnosis of prostate carcinoma, as well as in the identification of myoepithelial cells in other tissues including the breast. p63 is also a marker for squamous cell carcinoma. Recently, it was found that all p53 family members are involved in regulating the process of muscle differentiation through the retinoblastoma (RB) protein. Ablation of these p53 family functions blocks the differentiation program and promotes malignant transformation by enabling cooperating oncogenes to transform myoblasts. We therefore studied p63 expression in a number of neoplasms with myogenic differentiation. Immunohistochemical staining for p63 was performed on paraffin se...

2011-01-01

238

Brain glucose sensing and neural regulation of insulin and glucagon secretion

British Library Electronic Table of Contents (United Kingdom)

Glucose homeostasis requires the tight regulation of glucose utilization by liver, muscle and white or brown fat, and glucose production and release in the blood by liver. The major goal of maintaining glycemia at -5 mM is to ensure a sufficient flux of glucose to the brain, which depends mostly on this nutrient as a source of metabolic energy. This homeostatic process is controlled by hormones, mainly glucagon and insulin, and by autonomic nervous activities that control the metabolic state of liver, muscle and fat tissue but also the secretory activity of the endocrine pancreas. Activation or inhibition of the sympathetic or parasympathetic branches of the autonomic nervous systems are controlled by glucose-excited or glucose-inhibited neurons located at different anatomical sites, mainl...

2011-01-01

239

Automatic sample preparation of sulfonamide antibiotic residues in chicken breast muscle by using dynamic microwave-assisted extraction coupled with solid-phase extraction

British Library Electronic Table of Contents (United Kingdom)

Abstract In the work, a rapid, simple and high-throughput sample preparation method was developed for the determination of sulfonamide (SA) antibiotic residues in chicken breast muscle. The extraction and clean-up were online combined and up to 20 samples can be treated simultaneously in 6-min. The SAs were first extracted with acetonitrile under the action of microwave energy, and then the extract was directly introduced into the SPE column for on-line clean-up and concentration. Subsequently, the SAs eluted from the SPE column were determined by liquid chromatography-tandem mass spectrometry. The precisions of extraction results of 20 samples were in the range of 4.9-7.4%. The limits of detection and quantification obtained were in the range of 2.4-3.6-ng/g and 8.6-11.3-ng/g for SAs, res...

2011-01-01

240

Arterial stiffness is associated with low thigh muscle mass in middle-aged to elderly men

British Library Electronic Table of Contents (United Kingdom)

Objective: Sarcopenia of legs is an important cause of physical dysfunctions, frailty and dependence. Many predisposing and underlying mechanisms of sarcopenia, including age, sedentary life style, oxidative stress, insulin resistance, and low testosterone levels, are also known to be related to atherosclerosis, which is another leading cause of morbidity and mortality in elderly subjects. In this study, we investigated our hypothesis that sarcopenia and atherosclerosis are associated with each other to facilitate mutual abnormalities. Methods: Study was performed in apparently healthy 496 middle-aged to elderly persons recruited consecutively among the visitors to the medical check-up program, Anti-Aging Doc, in a University hospital, from March 2006 to December 2007. Mid-thigh muscle cro...

2010-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

241

Accumulation of glycosaminoglycans in radiation-induced muscular fibrosis

Turnover of whole body proteins and myofibrillar proteins in middle-aged active men

The content and biosynthesis of glycosaminoglycans (GAGs) were studied in pig thigh muscle after acute local {gamma}-irradiation. Seven months following irradiation, the muscular tissue next to the irradiation cone was replaced by severe mutilating fibrosis delimited by an intermediary perifibrotic zone. Results showed a parallel increase of collagen and GAG content in perifibrotic and fibrotic tissues. Sulphated GAGs, heparan sulphate and dermatan sulphate were preferentially accumulated in fibrotic tissue, while the hyaluronic acid content increased only slightly. Synthesis of sulphated GAGs was more elevated in fibrotic tissue than in perifibrotic zone as compared with normal muscle. Seven months after irradiation well-developed fibrotic tissue continued to synthesize and to accumulate extracellular matrix macromolecules. (Author).

1992-05-01

242

The Reliability Of Three Isokinetic Knee-extension Angle-specific Torques

Endurance-trained older men have a higher proportion of lean tissue and greater muscle cell oxidative capacity, reversing age-related trends and suggesting major changes in protein metabolism. In this study, protein turnover was determined in 6 middle-aged (52+/-1 yr) men who were well trained (VO_2 max 55.2+/-5.0 ml O_2/kg.min) and lean (body fat 18.9+/-2.8%, muscle mass 36.6+/-0.6%). The maintained habitual exercise while consuming 0.6, 0.9 or 1.2 g protein/kg.day for 10-day periods. N flux was measured from "1"5N in urea after oral "1"5N-glycine administration. Myofibrillar protein breakdown was estimated from urinary 3-methyl-histidine. Dietary protein had no effect on turnover rates, even when N balance was negative. Whole body protein synthesis was 3.60+/-0.12 g/kg.day and breakdown was 3.40+/-0.14 g/kg.day for all N intakes. Whole body protein flux, synthesis and breakdown were similar to values reported for sedentary young (SY) or ...

1986-04-13

243

Rosiglitazone and fenofibrate improve insulin sensitivity of pre-diabetic OLETF rats by reducing malonyl-CoA levels in the liver and skeletal muscle

To determine the reliability of concentric quadriceps muscle torque at 30°, 60°, and 75° of knee extension, 25 female university students were studied. Each subject was tested...Full Text Available

1993-01-01

244

Phospholamban and its Phosphorylated Form Interact Differently with Lipid Bilayers: A ³¹P, ²H and ¹³C Solid-State NMR Spectroscopic Study

AimsRosiglitazone and fenofibrate, specific agonists of the peroxisome proliferator activated receptors-γ (PPARγ) and -α (PPARα),...Full Text Available

2009-05-08

245

Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C

Phospholamban (PLB) is a 52-amino acid integral membrane protein that helps to regulate the flow of Ca²⁺ ions in cardiac muscle cells. Recent structural studies on the PLB pentamer...Full Text Available

2006-11-07

246

Measurements of prostaglandin biosynthesis in the gastrointestinal tract: biochemical and technical problems

Charcot-Marie-Tooth disease type 2C (CMT2C) is an autosomal dominant neuropathy characterized by limb, diaphragm, and laryngeal muscle weakness. Two unrelated families with CMT2C showed significant...Full Text Available

2010-02-01

247

Loughborough muscle men set for heavy duty for charity

The special features of prostaglandin biochemistry, of importance for investigation of the possible physiological roles of prostaglandins, are briefly reviewed. The formation of prostaglandins and related compounds from endogenous and exogenous arachidonic acid in homogenates of human gastric mucosal and muscle-serosal layers is described. These preliminary data seem to indicate that a low conversion of exogenous precursor does not necessarily mean that the capacity of the tissue to synthesize prostaglandins from endogenous precursor is low.

1981-01-01

248

Independent effects of weight and mass on plantar flexor activity during walking: implications for their contributions to body support and forward propulsion

... Jared Deacon, former Olympian and Commonwealth Gold Medallist, who coaches out of PowerBase and Loughborough's High Performance Athletics Centre, and Pete McKnight of Leicestershire County Cricket Club who formerly worked out of PowerBase with EIS and continues to work for UKA at the University, will also take ...

249

Dietary effects on body composition, glucose metabolism, and longevity are modulated by skeletal muscle mitochondrial uncoupling in mice

The ankle plantar flexor muscles, gastrocnemius (Gas) and soleus (Sol), have been shown to play important roles in providing body support and forward propulsion during human walking. However, there...Full Text Available

2008-08-01

250

Cytology of a giant adult-type rhabdomyoma of the tongue

Little is known about how diet and energy metabolism interact in determination of lifespan under ad libitum feeding. From 12 weeks of age until death, male and female wild-type (WT) and transgenic (TG)...Full Text Available

2011-02-01

251

British Library Electronic Table of Contents (United Kingdom)

Abstract Adult rhabdomyoma is a rare primary benign tumour of striated muscle origin that almost exclusively presents in the head and neck region with predilection for male. We herein report a case of an adult rhabdomyoma in a 67-year-old male with cytologic features. The lesions was located in the tongue extended to the left parapharyngeal region. We discuss the cytological findings with a brief review of the literature on this entity. Diagn. Cytopathol. 2010. 2010 Wiley-Liss, Inc.

2011-01-01

252

Calculated fluence spectra at neutron therapy facilities

Magnetic resonance imaging of the urogenital diaphragma in comparison with conventional histomorphological findings (the controversy about the deep transverse muscle of perineum); Kernspintomographische Untersuchungen des Diaphragma urogenitale im Vergleich mit korrespondierenden histomorphologischen Befunden (der Streit um den Misculus transversus perinei profundus)

The Monte Carlo transport codes LAHET and MCNP were used to calculate energy fluence spectra at three neutron therapy facilities. The results compare very favourably with measured data. Kerma spectra and the ratio of ICRU muscle tissue kerma to A-150 kerma, along the carbon to oxygen kerma ratio, were determined. Absorbed dose rate calculations are in reasonable agreement with measured values. Use of these codes to study modifications to existing therapy beams is briefly discussed. (author).

1995-11-13

253

Natural gas implementation in Turkey. Part 1: Turkey's natural gas demand and supplies

The transversus perinei profundus muscle is a well known structure in found anatomical textbook. Fibres of this muscle are believed to form the so-called external urethral sphincter (musculus sphincter urethrae). Recently histomorphologic investigations have shown that there is no muscular connection between the musculus sphincter urethrae (external sphincter) and the muscle system of the pelvic floor. Furthermore, the external sphincter was found to be divided into parts: The transversely striated part (musculus sphincter urethrae transversostriatus) and the smooth part (musculus sphincter urethrae glaber). Similar to histomorphologic investigations, contrast-enhanced MR imaging has shown the musculus sphincter urethrae to be surrounded by fatty and connective tissue only. Neither in MRI nor in anatomical slices can any connection between the urethral sphincter and the muscle system of the pelvic floor ...

1997-01-01

254

Controlling federal costs for coal liquefaction program hinges on management and contracting improvements

The main objective of the present study is to investigate Turkey's natural gas (NG) demand and supplies by giving the structure of the Turkish gas industry, NG pricing policy, and NG agreements. Turkey began to import NG from Russia in 1987 under a contract that provided for the delivery of 6 billion cubic meters annually (Bcma) for 25 years. The first contract, signed in 1988, stipulates delivery of 2 Bcma over a 20-yr period. The build-up of the Turkish gas market started by introducing gas in power generation in 1987 and in fertilizer production in 1988. Later contracts provide for total imports of 4 Bcma from the late 1990s. NG sales started at 0.5 Bcm in 1987 and reached to around 16 Bcm in 2001. Turkish NG demand is projected to increase extremely rapidly in coming years, with the prime consumers expected to be NG-fired electric power plants and industrial users. (author)

2004-02-01

255

Comparison of newer synthetic and biological wound dressings.

GAO's review of the H-Coal and Exxon projects showed inadequacies in DOE's contracting practices and a failure by DOE to properly plan, manage, and monitor, especially the H-Coal project. The initial Government-industry H-Coal agreements regarding the level of investment by private sponsors and the ceilings imposed on sharing in cost growth were imbalanced. Larger investments by private sponsors and sharing of cost growth provides an incentive to private sponsors to control costs and helps to assure that each party is fully committed to the success of the project. DOE started the H-Coal project prematurely before sufficiently detailed designs were available and without adequate project planning for functions such as construction scheduling, materials handling, inventory systems, and quality control. DOE staffing was inadequate at both projects to effectively monitor progress and contribute to timely decisions. Its contracts ...

1981-02-04

256

CHANGE@CERN:Changes in Industrial Services

In 18 piglets, weighing 10-15 kg, third-degree burns or full-thickness skin excisions of 4 X 4 cm were inflicted. The effect of five dressing materials on adhesiveness to the wounds, appearance, conformability, wound contraction, bacterial count, and morphology of the wound was studied at the end of the seventh and fourteenth days without dressing changes. In 11 piglets with a burn wound, the most adherent dressing was collagen sponge(CS), followed by polyurethane sponge (PU), pigskin xenograph (PS), and xeroform. CS more effectively debrided the wound from coagulated necrotic tissue than the other dressings. Wound contraction was maximal with CS dressing (52%), followed by PU (44%), xeroform (32%), and PS (27%). In another seven piglets with full-thickness excised wounds, a velour dressing made of polytetrafluoroethylene (PTFE) or PU adhered significantly more than CS or PS. Wound contraction was greater with CS (37%) or ...

1981-06-01

257

Annual progress report on the development of a 2 MW/10 second battery energy storage system for power disturbance protection

The changes envisaged in the Management's draft plan will focus the resources of the Laboratory on the LHC project and its completion. One of CERN's largest areas of spending is in Industrial Service Contracts, which currently amount to nearly 15% of the CERN budget. At present more than 2000 people have access to CERN through such contracts, although the nature of the contracts means that expenditure is not only on labour but also on materials. The revised cost to completion of the LHC has caused understandable concern that savings in Industrial Services will give rise to job losses at CERN, and rumours of '500 lay-offs' appeared in some newspaper reports. These reports were based on misunderstanding and speculation rather than the actual plan being prepared at CERN. The current proposal regarding expenditure on Industrial Services - which is supported by the findings of Task Force 3 - is to redirect about CHF170 M to the ...

2002-01-01

258

AP1000 plant construction in China: Ansaldo Nucleare contribution

Sandia National Laboratories (SNL), acting for the US Department of Energy (DOE), contracts for and administers programs for the purpose of promoting the development and commercialization of large scale, transportable battery energy storage systems. Under DOE Co-Op Agreement No. DE-FC04-94AL99852, SNL has contracted for the development and delivery of an initial prototype 250 kW bridge that becomes an integral subsystem of a 2 MW/10 Second System that can be used by utility customers to protect power sensitive equipment from power disturbances. Development work includes field installation and testing of the prototype unit at a participating utility site for extended product testing with subsequent relocation to an industrial or commercial participating utility customer site for additional evaluation. The program described by the referenced document calls for cost sharing with the successful bidder and eventual title transfer to the ...

1996-01-29

259

Reference materials to evaluate measurement systems for the nutrient composition of foods: results from USDA?s National Food and Nutrient Analysis Program (NFNAP)

On 24th of July 2007 Westinghouse Electric Co. signed landmark contracts with China's State Nuclear Power Technology Corporation (SNPTC), to provide four AP1000 nuclear power plants in China. The AP1000 is a two-loop 1117 MWe Pressurized Water Reactor (PWR). It is based on proven technology, but with an emphasis on safety features that rely on natural driving forces, such as pressurized gas, gravity flow, natural circulation flow and convection. Ansaldo Nucleare has provided a significant support to the passive plant technology development and, starting from 2000, is cooperating with Westinghouse to development of the AP1000 Plant. In the frame of the AP1000 Chinese agreement, Ansaldo Nucleare, in Joint Venture with Mangiarotti Nuclear, has signed a contract with Westinghouse for the design and the supply of innovative components to be installed in the first AP1000 unit to be constructed at the Sanmen site. The contract ...

2009-10-12

260

British Library Electronic Table of Contents (United Kingdom)

Over a 6.5-year period a total of 2554 values were reported by nine laboratories for 259 certified or reference nutrient concentrations in 26 certified reference materials (CRM) submitted to contract laboratories, blinded, as part of the qualifying process for analytical contracts and in the routine sample stream as part of the National Food and Nutrient Analysis Program. Each value was converted to a Z?-score, reflecting the difference from the assigned value related to the combined expected analytical uncertainty plus the uncertainty in the CRM value. Z?-scores >|3.0| were considered unacceptable. For some nutrients (Na, folate, dietary fiber, pantothenic acid, thiamin, tocopherols, carotenoids, monounsaturated, and polyunsaturated fatty acids), >20% of Z?-scores were >|3.0|. For total f...

2007-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

261

Developments in indirect coal liquefaction in slurry-phase and other reaction systems

Chern classes of graph hypersurfaces and deletion-contraction

This report accounts for Task 3 of DOE Contract No. AC01-81FE-05077. It reviews the developments in indirect coal liquefaction with emphasis on slurry-phase reactors and catalysis. This report also discusses topics related to indirect coal liquefaction research, such as analytical techniques in catalysis. The subjects covered in this report were selected by DOE. This report is the third and final task report of the three major tasks in this contract. The first task, ''Direct Coal Liquefaction Catalyst Development - Program Review and Research Perspectives'', was completed in November 1982. The second task, ''Review of Direct Coal Liquefaction by Slurry-Phase Catalysis'', was completed in September 1983. 47 refs., 66 figs., 50 tabs.

1984-02-01

262

Cell fate regulation by coupling mechanical cycles to biochemical signaling pathways

We study the behavior of the Chern classes of graph hypersurfaces under the operation of deletion-contraction of an edge of the corresponding graph. We obtain an explicit formula when the edge satisfies two technical conditions, and prove that both these conditions hold when the edge is multiple in the graph. This leads to recursions for the Chern classes of graph hypersurfaces for graphs obtained by adding parallel edges to a given (regular) edge. Analogous results for the case of Grothendieck classes of graph hypersurfaces were obtained in previous work. Both Grothendieck classes and Chern classes were used to define `algebro-geometric' Feynman rules. The results in this paper provide further evidence that the polynomial Feynman rule defined in terms of the Chern-Schwartz-MacPherson class of a graph hypersurface reflects closely the combinatorics of the corresponding graph. The key to the proof of the main result is a more general formula for the ...

2011-01-01

263

British Library Electronic Table of Contents (United Kingdom)

Many aspects of cellular motility and mechanics are cyclic in nature such as the extension and retraction of lamellipodia or filopodia. Inherent to the cycles of extension and retraction that test the environment is the production of mechano-chemical signals that can alter long-term cell behavior, transcription patterns, and cell fate. We are just starting to define such cycles in several aspects of cell motility, including periodic contractions, integrin cycles of binding and release as well as the normal oscillations in motile activity. Cycles of local cell contraction and release are directly coupled to cycles of stressing and releasing extracellular contacts (matrix or cells) as well as cytoplasmic mechanotransducers. Stretching can alter external physical properties or sites exposed b...

2009-01-01

264

VWS Westgarth supplies treatment systems for Daewoo FPSO vessel

British Library Electronic Table of Contents (United Kingdom)

VWS Westgarth, a subsidiary of Veolia Water Solutions & Technologies (VWS), has been awarded a multi-million dollar contract by Daewoo Shipbuilding & Marine Engineering Co (DSME), under which it will design, supply and deliver two treatment units for use on a floating production storage and offloading (FPSO) vessel.

2011-01-01

265

Utility battery storage systems program report for FY 94

Utility Battery Storage Systems Program report for FY93

Sandia National Laboratories, New Mexico, conducts the Utility Battery Storage Systems Program, which is sponsored by the US Department of Energy`s Office of Energy Management. The goal of this program is to assist industry in developing cost-effective battery systems as a utility resource option by 2000. Sandia is responsible for the engineering analyses, contracted development, and testing of rechargeable batteries and systems for utility energy storage applications. This report details the technical achievements realized during fiscal year 1994.

1995-03-01

266

Thermally actuated wedge block

Sandia National Laboratories, New Mexico, conducts the Utility Battery Storage Systems Program, which is sponsored by the US Department of Energy`s Office of Energy Management. In this capacity, Sandia is responsible for the engineering analyses, contract development, and testing of rechargeable batteries and systems for utility-energy-storage applications. This report details the technical achievements realized during fiscal year 1993.

1994-02-01

267

Theoretical Physics Divison progress report

This invention relates to an automatically-operating wedge block for maintaining intimate structural contact over wide temperature ranges, including cryogenic use. The wedging action depends on the relative thermal expansion of two materials having very different coefficients of thermal expansion. The wedge block expands in thickness when cooled to cryogenic temperatures and contracts in thickness when returned to room temperature.

1980-01-01

268

Satellite power systems (sps) concept definition study (Exhibit d). Volume 6, Part 1: cost and programmatics. Final report

The progress report for the Theoretical Physics Division of the United Kingdom Atomic Energy Authority, Harwell, 1985/6 is presented. The Division's research programme is divided into four sections - i) nuclear power (fuels, inspection and safety aspects), ii) radioactive waste management, iii) underlying research, and iv) non-nuclear contract research. The report contains a description of the research work carried out on these four topics in the above period. (U.K.).

269

Report of the Committee on Electric Utility Regulation

A summary of the cost data reviewed as well as conclusions and recommendations are presented. Cost and programmatic aspects of Rockwell's SPS CR-2 reference configuration were based on the results of several contracts with NASA and independent company-sponsored activities by the Space Operations and Satellite Systems Division of Rockwell International.

1981-01-01

270

Remote sensing of mine waste. Information Circular/1987

In 1991 the Federal Energy Regulatory Commission (FERC) continued it efforts to restructure the electric utility industry, emphasizing market-based pricing of wholesale power transactions and transmission access and pricing. Other issues covered in this report include pricing and policy initiatives, filing procedures, the generic rate of return on common equity, the price squeeze, contract interpretation, and legislative developments.

1992-01-01

271

Proof-of-concept testing of fluidized-bed copper oxide process. Phase 4, conceptual design and economic evaluation: Technical progress report No. 4-4, October 1992--March 1993

The report summarizes five separate Bureau of Mines contract studies on the use of aerial photogrammetry, satellite transmission of in situ instrumentation information, and satellite imagery to monitor and update mine waste embankment data. The equipment used, methods applied, results, recommendations, and cost analyses are presented along with a bibliography of related investigations.

1987-01-01

272

Progress report, December 1, 1979-November 30, 1980. [Chemical poisoning of heterogeneously catalyzed reactions on transition metal surfaces

The objective of Phase IV of the contract is to design a conceptual flue gas treating unit based on the fluidized-bed Copper Oxide (FBCO) process for a new coal-fired 500 MW(e) power plant. A technical and economic evaluation of the FBCO process, based on the conceptual design, will also be completed. Progress is described.

1993-09-01

273

Prime Contract Awards Alphabetically by Contractor, State or ...

The mechanism of chemical poisoning of model heterogeneously catalyzed reactions on transition metal surfaces is studied. Clean Mo(001) surfaces were characterized; results suggest a first-layer contraction of 10% of the bulk interlayer spacing. Characterization of clean Co(0001) surfaces is underway. Decomposition of formic acid on Mo(001) surfaces is being studied. (DLC)

1980-01-01

274

Non-aqueous electrode research. Interim technical report, 1 October 1978-25 October 1979

... Iv mc.4N0 Kt afl qtl- 04n4 ( (Y 4 3.4 0.NO K0 00 0. 04 N oC 0 000 000 04 K1 0 a -# 0.N K) 0 0 0 00 00 a 0 0 0 00 0 C0 K ...

2011-05-14

275

Molecular model for de Vries type smectic A - smectic C phase transition in liquid crystals

This report describes work carried out in the second 13 months of a 33 month contract to characterize the passive films formed on anodes commonly used in non-aqueous battery cells, and to identify cell reaction products formed at the carbon cathode commonly used in these cells.

1980-03-01

276

Kaluza-Klein mixmaster universes

We develop a theory of Smectic A - Smectic C phase transition with anomalously weak smectic layer contraction. We construct a phenomenological description of this transition by generalizing the Chen-Lubensky model. Using a mean-field molecular model, we demonstrate that a relatively simple interaction potential suffices to describe the transition. The theoretical results are in excellent agreement with experimental data.

2007-01-01

277

Kaluza-Klein mixmaster universes

We analyze the behavior of some Bianchi type-IX, mixmaster cosmological models possessing extra dimensions. We find that, unlike the three-dimensional case, they do not exhibit chaotic behavior on approach to their initial singularity. A finite sequence of stochastic mixmaster oscillations is, in general, replaced by monotonic contraction of the three-space scale factors on approach to a singularity whenever additional spatial dimensions exist with the metric form we consider.

1985-09-15

278

Interconnection France-England; Interconnexion France-Angleterre

We analyze the behavior of some Bianchi type-IX, mixmaster cosmological models possessing extra dimensions. We find that, unlike the three-dimensional case, they do not exhibit chaotic behavior on approach to their initial singularity. A finite sequence of stochastic mixmaster oscillations is, in general, replaced by monotonic contraction of the three-space scale factors on approach to a singularity whenever additional spatial dimensions exist with the metric form we consider.

279

Government to buy low-cost energy from non-utility sources

These documents defines the interconnection France-England rules for the 2000 MW DC submarine cable directly linking the transmission networks of England and Wales and France. Rights to use Interconnector capacity from 1 April 2001 are to be offered through competitive tenders and auctions, full details of which are set out in the Rules. The contract and a guide to the application form are provided. (A.L.B.)

2001-07-01

280

Formula Not Shown surface diffeomorphisms have symbolic extensions

Power generated by manufacturers and third-party suppliers in venture capital projects is available to military and other government users at a cost 10 to 20% lower. Tax benefits and other financial incentives keep suppliers' costs low. Users are required to contract for a minimum amount of energy over a 20- to 30-year period. Military use of these energy projects includes sources based on solar energy, cogeneration, geothermal heat, and refuse-derived fuel. (DCK)

1983-04-04

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

281

British Library Electronic Table of Contents (United Kingdom)

We prove that Formula Not Shown surface diffeomorphisms have symbolic extensions, i.e. topological extensions which are subshifts over a finite alphabet. Following the strategy of Downarowicz and Maass (Invent. Math. 176:617?636, 2009) we bound the local entropy of ergodic measures in terms of Lyapunov exponents. This is done by reparametrizing Bowen balls by contracting maps in a approach combining hyperbolic theory and Yomdin?s theory.

2011-01-01

282

Energy storage systems program report for FY1996

Dynamical evolution and molecular abundances of interstellar clouds

Sandia National Laboratories, New Mexico, conducts the Energy Storage Systems Program, which is sponsored by the US Department of Energy`s Office of Utility Technologies. The goal of this program is to assist industry in developing cost-effective energy storage systems as a resource option by 2000. Sandia is responsible for the engineering analyses, contracted development, and testing of energy storage systems for stationary applications. This report details the technical achievements realized during fiscal year 1996.

1997-05-01

283

Development of a retrofit coal combustor for industrial applications

Dynamical models are presented that start with interstellar gas in an initial diffuse state and consider their gravitational collapse and the formation of dense cores. Frozen-in tangled magnetic fields are included to mimic forces that might oppose gravitational contraction and whose effectiveness may increase with increasing core densities. Results suggest the possibility that dense cloud cores may be dynamically evolving ephemeral objects, such that their lifespan at a given core density decreases as that density increases. 66 refs.

284

Detection of TNT and Picric Acid on Surfaces and in Seawater by Using Photoluminescent Polysiloles This work was supported through DARPA's Tactical Sensors Program through a Space and Naval Warfare Systems Center Contract (N66001-98-C-8514) and the National Science Foundation, Division of Material Research (Grant No. DMR 9900034). The technical point of contact for this DARPA program is Dr. Edward Carapezza.

In this first quarterly technical report for DOE Contract No. DE-AC22-87PC79654, a description of the background, technology, and application is provided. The design and fabrication of advanced combustion chambers were completed during this period. Initial testing on both the bare metal and refractory lined advanced chambers were initiated. The units were tested initially with gas but primarily with coal. A Pittsburgh No. 8 pulverized coal was used for these test activities. Both advanced chambers pulsed well.

1987-01-01

285

Environmental Research Database

PMID:11433457

2001-06-01

286

CCMAP Contract

DescriptionCEH - Quest CCMAP see http://quest.bris.ac.uk/research/themes/CCMAP.html CCMAP (Climate-carbon modelling, assimilation and prediction) Leader: Dr. Eleanor Blyth (CEH, Wallingford) Overview and Goals CCMAP is one of QUEST's Theme 1 projects and is about to be commissioned to the Centre for Ecology and Hydrology at Wallingford. The Principal Investigator will be Dr. Eleanor Blyth, with subcontracts to the Universities of Bristol (Dr. Wolfgang Knorr, Earth Sciences and QUEST; Andy Ridgw [continued...

287

?_1A/B-Knockout mice explain the native ?_1D-adrenoceptor's role in vasoconstriction and show that its location is independent of the other ?₁-subtypes

48 CFR 35.017-7 - Limitation on the creation of new FFRDC's.

Background and purpose:Theoretically, three α₁-adrenoceptor subtypes can interact at the signalling level to alter vascular contraction or at the molecular level...Full Text Available

2009-12-01

288

(Feasibility study of the San Lorenzo River hydroelectric project)

...2010-10-01 2010-10-01 false Limitation on the creation of new FFRDC's. 35.017-7 Section 35.017-7 ...DEVELOPMENT CONTRACTING 35.017-7 Limitation on the creation of new FFRDC's. Pursuant to 10 U.S.C....

2010-10-01

289

Aortic non communicating dissections. A study with helical CT

I travelled to San Jose, Costa Rica on July 8, 1990 to evaluate all of the completed elements of the ongoing feasibility study for the San Lorenzo River hydroelectric project. The feasibility study is being supported by ORNL under the Renewable Energy Applications and Training Project. The project is being studied for implementation by CONELECTRICAS, a consortium of rural electric cooperatives and the study itself is being conducted by BEL Engineering, a Costa Rican consulting firm under contract to CONELECTRICAS, USAID/PIC and NRECA.

1990-07-19

290

Ultrastructural effect of gamma radiation on grass shrimps (Penaeus monodon Fabricius)

The evaluate the signs of aortic intramural hematoma with helical CT and the diagnostic role of this technique in patients with this condition. It was reviewed the CT findings of 396 patients submitted to emergency examinations for suspected aortic dissection from 1995 to 1999. Only 18 patients (6 women and 12 men) had CT signs of aortic intramural hematoma. Helical CT studies were carried out with the following parameters: slice thickness 10 mm, reconstruction index 10, feed 1.5 mm, conventional algorithm with minimum values of 130 kV and 125mA. All patients were examined with dynamic contrast-enhanced CT, before and after a power injection of 130 mL ionic contrast material. It was studied: hematoma localization and longitudinal extension; thickness and density of aortic wall; presence and location of intimal calcifications; integrity of intimal wall; hemo mediastinum and/or hemo thorax. Aortic wall thickening appeared as a high density crescent-shaped area at baseline CT and had low ...

2000-09-01

291

Ultrastructural effect of gamma radiation on grass shrimps (Penaeus monodon Fabricius)

The effect of ionizing radiation (2, 5, and 10 KGy of gamma rays) on muscle ultrastructure of grass shrimps (Penaeus monodon Fabricius) tails at ambient or frozen (-18{sup 0}C) temperature was investigated by transmission electron microscopy (TEM). No significant change was found in muscle ultrastructure of shrimp meat irradiated at doses of 2 or 5 KGy and then stored at 4{sup 0}C for 0 and 8 days. However, in shrimps which were irradiated at ambient temperature at a dose of 10 KGy, the margin of A-band of the myofibrils in longitudinal sections exhibited an irregular zig-zag pattern. In cross section some myosin filaments in the A-band regions were missing. A possible interpretation of these results would be that 10 KGy gamma irradiation dose at ambient temperature depolymerized myosin in the A-band from the tail of thick filament. Actin damage was also observed in some cross sections. Irradiation damage of sarcoplasmic membranes appeared in ...

1990-01-01

292

The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding

The effect of ionizing radiation (2, 5, and 10 KGy of gamma rays) on muscle ultrastructure of grass shrimps (Penaeus monodon Fabricius) tails at ambient or frozen (-18"0C) temperature was investigated by transmission electron microscopy (TEM). No significant change was found in muscle ultrastructure of shrimp meat irradiated at doses of 2 or 5 KGy and then stored at 4"0C for 0 and 8 days. However, in shrimps which were irradiated at ambient temperature at a dose of 10 KGy, the margin of A-band of the myofibrils in longitudinal sections exhibited an irregular zig-zag pattern. In cross section some myosin filaments in the A-band regions were missing. A possible interpretation of these results would be that 10 KGy gamma irradiation dose at ambient temperature depolymerized myosin in the A-band from the tail of thick filament. Actin damage was also observed in some cross sections. Irradiation damage of sarcoplasmic membranes appeared in the ...

293

The diagnosis of inflammatory muscular and vascular conditions using MRT with STIR sequences

Myostatin is a member of the transforming growth factor-{beta} (TGF-{beta}) family and a strong negative regulator of muscle growth. Here, we present the crystal structure of myostatin in complex with the antagonist follistatin 288 (Fst288). We find that the prehelix region of myostatin very closely resembles that of TGF-{beta} class members and that this region alone can be swapped into activin A to confer signalling through the non-canonical type I receptor Alk5. Furthermore, the N-terminal domain of Fst288 undergoes conformational rearrangements to bind myostatin and likely acts as a site of specificity for the antagonist. In addition, a unique continuous electropositive surface is created when myostatin binds Fst288, which significantly increases the affinity for heparin. This translates into stronger interactions with the cell surface and enhanced myostatin degradation in the presence of either Fst288 or Fst315. Overall, we have identified several ...

2009-09-29

294

Smooth muscle myosin heavy chain locus (MYH11) maps to 16p13. 13-p13. 12 and establishes a new region of conserved synteny between human 16p and mouse 16

The role of MRT in the prebiopsy diagnosis of muscular and vascular inflammatory conditions was evaluated prospectively and an optimal method of examination was investigated. 92 patients with a suspected diagnosis of myositis (60 cases) or vasculitis (32 cases) were examined, in each case two extremities were studied using transverse T_1 and T_2 weighted SE sequences and double echo STIR sequences on a 0.5 Tesla (56 patients) or 1.5 Tesla magnet (36 patients; T5/S15 Gyroscan, Philips). The site of the biopsy depended on the MRT findings. In 41 patients the suspected diagnosis was confirmed histologically, in two patients an infective myositis was diagnosed on clinical grounds despite negative histology. MRT demonstrated muscle oedema in 86% of patients. There were negative findings after immuno-suppressive therapy (two patients), in focal myositis (3 out of 4 patients) and in one of 7 patients with untreated vasculitis. Amongst 49 patients in whom the suspected ...

295

Repair of the radiation induced rectovaginal fistulas without or with interposition of the bulbocavernosus muscle (Martius procedure)

The human smooth muscle myosin heavy chain locus (MYH11) was mapped by fluorescence in situ hybridization to the middle of the p arm of chromosome 16 using a genomic cosmid clone containing coding sequences of the gene as probe. Probe from coding sequence, when applied to Southern blots of a panel of hybrids containing different portions of human chromosome 16, localized the gene to 16p13.13-13.12. Coding sequence PCR primers, when used on the DNA from a CHO-mouse hybrid clone mapping panel informative for mouse chromosomes, showed that the gene was located on mouse chromosome 16. These results correct a recent assignment of MYH11 from 16q12.2 to the region of the 16p-arm inversion breakpoint seen in acute myelomonocytic leukemia (AMML) M4Eo and demonstrate that the conflicting data do not result from the presence of additional MYH genes on the q arm of the chromosome. Also, a new region of conserved synteny between human 16p and mouse 16 is established. 10 refs., ...

1993-10-01

296

Preparation and biodistribution of technetium-99m-labeled 1-(2-nitroimidazole-1-yl)-propanhydroxyiminoamide (N2IPA) as a tumor hypoxia marker

Two local repair procedures, one without (9) and the other with (14) a bulbocavernosus muscle graft were performed on 20 patients with a radiation induced rectovaginal fistula. Four patients had two procedures successively. The initial success rate of both procedures was 7/9 and 14/14 respectively. Though the initial result of the bulbocavernosus graft was obviously better, in many of the local repair procedures, subclinical radiation damage progressed, resulting in recurrence of rectovaginal fistula (5), rectovesical fistula (4), pararectal abscess (2) etc. After a mean follow up of around 10 years, the success rate of fistula repair decreased to 5/9 and 13/14 and only 2/9 and 6/14 finally remained without a colostomy. A local repair operation should be restricted to carefully selected cases. The musculus gracilis is proposed as a better vascular graft. If the general condition of the patient does not allow more aggressive reconstructive procedures, fistula repair ...

1988-04-01

297

Magnetic resonance appearance of peripheral nerve sheath tumors

A new hydroxyiminoamide ligand, 1-(2-nitroimidazole-1-yl)-propanhydroxyiminoamide (N2IPA) was synthesized. The biodistribution of {sup 99m}Tc-N2IPA in mice bearing S180 tumor demonstrated that the complex showed a selective accumulation in tumor and slow clearance from it. The tumor-to-tissue uptake ratios increased with time. At 4 hours after injection, the uptake ratios of tumor to muscle, blood, liver, heart, and lung reached 8.4, 1.5, 0.6, 2.9, and 2.3, respectively. Moreover, the tumor-to-liver uptake ratio steadily increased to 0.9 at 8 hours and 2.3 at 24 hours. The complex showed little uptake and quick clearance in blood, lung and other organs. Compared with other proposed hypoxia-imaging agents, this novel agent has advantages of higher tumor-to-muscle and tumor-to-blood uptake ratios and easier synthesis.

2004-02-01

298

Insulin-like effects in the rat of the purified growth factor from Spirometra mansonoides plerocercoids.

Magnetic resonance imaging (MRI) was used to evaluate 22 histological proven peripheral nerve sheath tumors, approximately two-thirds of which arose in the lower extremity. The histologic distribution was as follows: 12 schwannomas, 7 neurofibromas, and 3 malignant peripheral nerve sheath tumors (2 of which occurred in patients with neurofibromatosis). Most lesions demonstrated an intermediate to moderately bright signal on T_1-weighted images and were minimally inhomogeneous. All lesions were moderately bright on T_2-weighted images, again with variable inhomogeneity. The extent of the tumor was best assessed on proton-density- and T_2-weighted images. Smooth margins were noted in 19 lesions. Of the 3 remaining lesions, 2 were malignant (but had been subjected to biopsy prior to MRI), and the other lesion was a plexiform neurofibroma. MRI accurately determined the relationship between the lesions and the adjacent neurovascular structures and muscles, thereby ...

299

Immunolocalization of endothelin-B receptor in mouse intestinal tract.

The acute effects of injections of the human growth hormone-like factor purified from plerocercoids of the tapeworm Spirometra mansonoides on carbohydrate, lipid, and protein metabolisms were determined in intact rats. Male rats were injected ip with saline, insulin, or various doses of partially purified PGF. The rats injected with insulin had significantly reduced serum glucose concentrations but no dose of PGF caused a change in serum glucose levels. Insulin and PGF stimulated [14C]glucose and [14C]leucine oxidation to 14CO2 in adipose tissue and muscle and increased incorporation of both [14C]glucose carbons into lipids and [14C]leucine into protein in fat and muscle. The responses to PGF were dose-dependent and persisted after 3 hr of incubation in vitro. Injections of naloxone prior to injecting PGF to block the stress response did not prevent the stimulation of insulin-like responses by PGF. Therefore, PGF has intrinsic insulin-like ...

1987-05-01

300

Evaluation of magnetization transfer ratios for breast tissues and breast diseases

The endothelin-B (ETB) receptor is a G-protein-coupled receptor that binds endothelin ligands and is essential for the development of epidermal melanocytes and enteric neurons. Recent reports indicate that ETB is localized to nuclei in cardiac ventricular myocytes, although it has been thought that ETB is localized mainly on the plasma membrane. It remains unknown, however, whether this unique distribution of ETB occurs in other tissues. To elucidate the subcellular distribution of ETB in the intestine, we performed immunofluorescence of ETB in mouse intestine using a specific antibody. ETB-like immunoreactivity was detected in both the mucosal and muscle layers. In the mucosal layer, villous epithelial cells, stromal cells of the lamina propria, and cryptic cells were immunostained. Subcellularly, ETB is localized mainly to the nuclei of villous epithelial cells. In the muscle layer, immunoreactivity of ETB was localized to the myenteric ...

2004-11-01

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301

Distribution of /sup 14/C after oral administration of (1-/sup 14/C)linoleic acid in rats fed different levels of essential fatty acids

To determine MTRs for normal structures and benign diseases in the breast two-dimensional magnetization transfer imaging was performed in 62 patients and in 3 young female volunteers. With regard to the MTRs of measurements in the normal breast tissues, fat tissues which is close to simple cysts in MTRs show little transfer of longitudinal magnetization. MTRs of the muscles was 15.15{+-}6.22%, which exceeded those of breast parenchyma. The breast parenchyma didn`t show the change of MTR value due to the difference of patient age and due to variable amount of fat and fibrous tissues. Breast parenchyma in the two young volunteers clearly showed biphasic change of MTR values in accordance with the menstrual cycle; little transfer value was due to hydration in the postovulatory period and high transfer value was due to dehydration in the preovulatory period. In the remaining one volunteer during lactation period, mammary parenchyma shows sever decrease in MTR, because ...

1997-03-01

302

Direct photoaffinity labeling by nucleotides of the apparent catalytic site on the heavy chains of smooth muscle and Acanthamoeba myosins

Rats from an inbred Sprague-Dawley strain were fed semisynthetic diets with a low (0.3 energy percent (en %)), normal (3 en %) or high (10 en %) content of essential fatty acids (EFA) for at least three generations. Twenty-nine- to 33-day-old male rats were given a single intragastric dose of (1-14C)linoleic acid in olive oil, and the respiratory CO2, urine and feces were collected for 46 hours (expt 1) or 20 hours (expt 2). The 14C activity in respiratory CO2, feces, urine and the carcass was determined in both experiments. In experiment 2 it was also measured in samples of the brown fat, liver, adrenals, white fat, skeletal muscles and brain. In both experiments the rats fed the low EFA diet retained significantly more 14C activity than the rats fed the normal or high EFA diets. In all groups the concentration of label was highest in the brown fat and the adrenals, but the above differences among the groups with respect to 14C retention were mainly observed in ...

1984-09-01

303

Development of a methodology to assess organometallic effects on bioenergetic systems

The heavy chains of Acanthamoeba myosins, IA, IB and II, turkey gizzard myosin, and rabbit skeletal muscle myosin subfragment-1 were specifically labeled by radioactive ATP, ADP, and UTP, each of which is a substrate or product of myosin ATPase activity, when irradiated with uv light at 0"0C. With UTP, as much as 0.45 mol/mol of Acanthamoeba myosin IA heavy chain and 1 mol/mol of turkey gizzard myosin heavy chain was incorporated. Evidence that the ligands were associated with the catalytic site included the observations that reaction occurred only with nucleotides that are substrates or products of the ATPase activity; that the reaction was blocked by pyrophosphate which is an inhibitor of the ATPase activity; that ATP was bound as ADP; and that label was probably restricted to a single peptide following limited subtilisin proteolysis of labeled Acanthamoeba myosin IA heavy chain and extensive cleavage with CNBr and trypsin of labeled turkey gizzard myosin heavy ...

304

Anatomic and radiologic correlations in spontaneous hematomas of the rectus abdomninis muscles; Correlazioni anatomo-radiologiche negli ematomi spontanei dei muscoli retti dell'addome

A methodology for assessing the impact of subacute concentrations of organometallic agents on bioenergetic and oxidative damage processes in animals, cells and energy transducing subcellular organelles is being developed. Several of the assays are noninvasive and thus lend themselves to human tests. At the whole-animal level we utilize a treadmill chamber where physiological parameters of exercising animals are monitored. These include parameters of whole animals' work performance such as oxygen consumption, carbon dioxide evolution and endurance. Oxidative damage can be monitored in experiments by analyzing expired air of the animals for ethane and n-pentane. These alkanes correlate with lipid peroxidation in vivo. At the cellular and subcellular levels, respiratory activity, lipid peroxidation and free radical species are assayed. Respiratory activity is measured in muscle homogenates and isolated mitochondria using substrates which feed into different ...

1981-06-01

305

[The simulation of 137Cs distribution in forest ecosystems and prediction of its accumulation by forest products].

Rectus sheath hematomas are a frequent but sometimes misdiagnosed disease in patients under anticoagulative drugs, hemodialysis, or simply in the elderly. The most frequent localization is in the lower part of the abdomen: the explanation lies in the anatomy of the abdominal wall, especially in the arcuate line of the rectus sheath. Aim of this work is to explain the reason of the almost constant location correlating the anatomy with the CT features. The rectus abdominis muscle lies between the aponeuroses of the transverse and oblique muscles which form the so called rectus sheath. This arrangement is found from the costal arch to a level approximately between the umbilicus and the pubic symphisis, where the rear layer of the rectus sheath ends with a curved edge, called the arcuate or semicircular line of Douglas. Beneath this line the aponeuroses of the three muscles pass in front of the rectus which is separated from ...

2000-06-01

306

The early days of parathyroid surgery.

A mathematical model of 137Cs migration in forest ecosystem is presented, which describes the behaviour of this radionuclide in the forest litter-soil system, trees, understory and forest animals. The model's parameters for different types of forest ecosystems are estimated and model's adequacy is tested through the use of independent experimental data. The sensitivity of the model's output variables is analyzed to variations in the most significant parameters. The differences in the seasonal and mean annual dynamics of 137Cs concentration in muscles of roe deers and mooses are shown to be defined by specific features of the diets of these animals and variations in 137Cs content in the main diet components. PMID:11402557

307

Recent advances in pharmacotherapy for dyspnea in COPD

The parathyroid endocrine glands, usually four in number and about the size of a split pea, lie on either side of the posterior aspect of the thyroid gland. Occasionally one or more of these structures are found in an aberrant position in the neck or even in the superior mediastinum. The parathyroid secretion, parathormone, regulates the level of serum calcium within sharply defined limits. Lack of parathormone, with lowering of the serum calcium, results in hyper-irritability of skeletal muscle, the clinical condition known as tetany. This is encountered following inadvertent removal or bruising of the parathyroid glands at thyroidectomy. PMID:21488463

2011-03-01

308

British Library Electronic Table of Contents (United Kingdom)

Dyspnea is the most distressing symptom experienced by those suffering from advanced stages of chronic obstructive pulmonary disease (COPD). Activity-related dyspnea in COPD is multifactorial but is associated with increased central neural drive, impaired dynamic respiratory mechanics and abnormal respiratory muscle function. Each of these components can potentially be targeted for pharmacotherapy. Recent advances in the pharmacotherapy of COPD include the development of new long-acting bronchodilators which, when combined, provide sustained improvements in dyspnea. Additionally, novel applications of older therapies such as opiates, furosemide, helium-oxygen, and statins show early promise as dyspnea-relieving interventions in COPD. Effective pharmacological manipulation of the affective ...

2011-01-01

309

Radiolabelling of. cap alpha. -bungarotoxin to high specific radioactivity with complete retention of biological activity

Radioimmunoassay of serum myoglobin in polymyositis and other conditions

Radioiodinated ..cap alpha..-bungarotoxin, the venom of Bungarus multicinctus, is commonly used for the detection and quantification of nicotinic acetylcholine receptors (nAChR) and anti-nAChR antibodies. A radioiodination method is described which is simple and yields a fully active product which, after fractionation, has a specific activity tenfold higher (900 Ci/mmol) than those routinely used, resulting in enhanced sensitivity of assays and conservation of material, especially muscle extracts.

1984-10-01

310

Primary leiomyosarcoma of the prostate with lung metastasis: Report of a case diagnosed by fine-needle aspiration cytology

Radioimmunoassay of serum myoglobin was done in 53 patients with polymyositis syndromes and other conditions. Serum myoglobin values in 33 healthy subjects ranged from 4 to 77 [mean 33.3 +/- 19.8 (SD)] ng/ml. Fifty percent of polymyositis patients had elevated serum myoglobin levels (greater than 80 ng/ml). Serum myoglobin values in polymyositis patients fluctuated more sensitively than CPK and GOT. Combined estimation of myoglobin and CPK offers advantages for the detection of muscle injury and the prediction of disease exacerbation.

311

British Library Electronic Table of Contents (United Kingdom)

Abstract Prostate leiomyosarcoma is an extremely rare and highly aggressive neoplasm that accounts for less than 0.1% of primary prostate malignancies. Herein, we present a patient with primary leiomyosarcoma of the prostate with lung metastasis diagnosed primarily on fine-needle aspiration cytology. Characteristic cytological features such as small fascicles of spindle cells with blunt-ended nuclei, positivity for desmin and smooth muscle actin along with the radiological features are helpful in the correct diagnosis. Diagn. Cytopathol. 2010. 2010 Wiley-Liss, Inc.

2011-01-01

312

Muscarinic and nicotinic activities of the novel acetylcholine analog acetylselenonium choline.

IMAGING DIAGNOSIS-SYNOVIAL MYXOMA OF LUMBAR VERTEBRAE ARTICULAR PROCESS JOINT

The present paper further characterizes the cholinergic properties of acetylselenonium choline (ASeCh, (CH3)2Se+CH2CH2OCOCH3). The data demonstrate that ASeCh possesses muscarinic receptor agonist properties as evidenced by vasodepressor and smooth muscle contractile activities which are enhanced by physostigmine and antagonized by atropine. ASeCh also possessed nicotinic agonist activity on frog rectus abdominis tissue which was potentiated by physostigmine, and blocked by d-tubocurarine. The relative potencies of ASeCh ranged from approximately 1% to approximately 6% of the potency of acetylcholine in the three types of preparations examined. PMID:1435078

1992-01-01

313

British Library Electronic Table of Contents (United Kingdom)

Magnetic resonance (MR) imaging and histopathology were used to diagnose an articular process synovial myxoma in a dog. On MR images, the tumor was characterized by distortion of the left L1-L2 articular process, widening of the articular process joint, and the presence of a mass contiguous with the synovium of the articular process that displaced the spinal cord. The tumor was T2-hyperintense, T1-hypointense, relative to muscle, and had mild contrast enhancement. The MR features of articular process synovial myxoma may be distinct from other diseases of the articular process joint.

2011-01-01

314

Back pain in the osteoporotic individual: A physiatric approach

British Library Electronic Table of Contents (United Kingdom)

Back pain from osteoporosis is commonly related to compression fractures. The patient with vertebral compression fractures additionally suffers from an ongoing risk of recurrent fractures and postural abnormalities that can result in impaired respiratory function, leading to increased risk of morbidity. Weakened back muscles, especially the back extensor group, are felt to contribute significantly to this risk. The combination of pharmacologic and nonpharmacologic interventions, through physical activity, exercise, and modalities, are potential interventions that could be used to help reduce the pain of osteoporotic compression fractures as well as potentially reducing recurrent fracture rates.

2011-01-01

315

Radiologic findings of extraosseous Ewing's sarcoma

Distributions of "1"3"7Cs, "2"0"1T1, "2"0"3Hg, "2"0"3Pb and "5"7Co in a rat hepatoma model. Comparison with "6"7Ga

The purpose of this study is to evaluate the radiologic findings of the extraosseous Ewing's sarcoma. Six patients with pathologically confirmed extraosseous Ewing's sarcoma were retrospectively reviewed. Patients included two men and four women with an average age of 21.5 years (age range 9-48 years). Plain radiographs (six patients), magnetic resonance (MR) images (five patients), computed tomographic (CT) scans (three patients) and whole body scintigraphy (two patients) were reviewed and analyzed. Images were evaluated with regard to lesion location, size, margin, muscle or bone involvement and intrinsic imaging characteristics on CT and MRI. The tumors were located in the thigh (three patients), back (two patients) and upper arm (one patient). The tumors ranged in size from 2.3 cm to 7.5 cm (mean, 5.2 cm), were mainly well circumscribed and showed no evidence of calcification prior to treatment. Margins were well defined in four out of the six patients. Four ...

2005-09-01

316

Cs-137 concentrations in the muscles of Walleye Pollack

The distribution of carrier-free "2"0"3Pb-acetate, "2"0"3HgCl_2, "5"7Cocl_2, "1"3"7CsCl and "2"0"1TlCl was investigated in rats bearing thigh-implanted Morris 7777 hepatomas. Viable and nonviable tumor tissue was collected in order to determine the relative affinities of the radiopharmaceutical for these tissues. The animals were sacrificed at 4, 24, 48, 72 and 96 hrs following intravenous injection. Washout of the radioisotope from the viable tumor tissue was rapid, the maximum concentration being reached on or before 4 hrs following injection. In contrast, residual activity within the nonviable tumor tissue decreased much more slowly and in some cases even increased with time. Viable tumor-to-muscle and nonvialbe tumor-to-muscle ratios for "2"0"3Pb, "2"0"3Hg and "5"7Co were comparable to the analogous ratios reported for "6"7Ga. However, none of these isotopes approached "6"7Ga as a potential tumor imaging agent because the large ratios were ...

317

Cloning of human basic A1, a distinct 59-kDa dystrophin-associated protein encoded on chromosome 8q23-24

High concentrations of Cs-137 were detected in the muscles of Walleye Pollack (Theragra chalcogramm) collected from Kitamiyamato banks (sampling on 25 Jul. 2000), Kamui area (16 Oct. 2000) and Niigata coasts (31 Jan. 2001). The concentrations were 0.35 #+-# 0.01, 0.41 #+-# 0.01, and 0.63 #+-# 0.02 Bq/kg-wet, respectively. The average concentration in our past investigations was about 0.25 #+-# 0.01 Bq/kg-wet. Samples from other areas, the coat of Kushiro (8 May 2001), North Tishima (13 Nov. 2000) and the Sea of Okhotsk (6 May 2001), had the average concentrations. There were no such high concentrations of Cs-137 in other fish species collected from Kitamiyamato banks, Kamui area, and Niigata coasts. Fish samples with high concentrations all make the migration in the north of Japan sea. These results would indicated that samples took in Cs-137 elements from sea-water or foods on the migration route. Cs-137 concentrations in muscles of walleye ...

2003-08-17

318

Bioconcentration of "1"4 C-Carbofuran and "1"4 C- Lindane in fresh water Tilapia Nilitica and the bioavailability of their residues to rats

Duchenne and Becker muscular dystrophies are caused by defects of dystrophin, which forms a part of the membrane cytoskeleton of specialized cells such as muscle. It has been previously shown that the dystrophin-associated protein A1 (59-kDa DAP) is actually a heterogeneous group of phosphorylated proteins consisting of an acidic ({alpha}-A1) and a distinct basic ({beta}-A1) component. Partial peptide sequence of the A1 complex purified from rabbit muscle permitted the design of oligonucleotide probes that were used to isolate a cDNA for one human isoform of A1. This cDNA encodes a basic A1 isoform that is distinct from the recently described syntrophins in Torpedo and mouse and is expressed in many tissues with at least five distinct mRNA species of 5.9, 4.8, 4.3, 3.1, and 1.5 kb. A comparison of the human cDNA sequence with the GenBank expressed sequence tag (EST) data base has identified a relative from human skeletal ...

1994-05-10

319

Using calibrated engineering models to predict energy savings in large-scale geothermal heat pump projects

Tilapia Nilotica were exposed to "1"4 C- carbofuran (125 MUg/1) and "1"4 C - lindane (80 MUg/1) for 96 h. Uptake period followed by 8 days depuration period. The bioconcentration factor (BCF) for carbofuran reached 32.4 at 12 h and 82 for lindane at 48 h. The amount of "1"4 C-activity found in fish treated with "1"4 C - carbofuran after the uptake period showed the following descending order: viscera > remaining parts > gills > muscles. In case of "1"4 C - lindane treated fish the recovered amount followed the order; remaining parts> viscera > gills muscles. During the depuration period, carbofuran residues taken up by fish were eliminated in 2 phases, an initial rapid phase followed by a slower gradual one. However, the rate of elimination in case of lindane was much slower especially during the first 2 days. At the end of the depuration period (8 days), the muscles (edible portion) contained 10% and 58% of ...

1997-07-01

320

Using Calibrated Engineering Models To Predict Energy Savings In Large-Scale Geothermal Heat Pump Projects

Energy savings performance contracting (ESPC) is now receiving greater attention as a means of implementing large-scale energy conservation projects in housing. Opportunities for such projects exist for military housing, federally subsidized low-income housing, and planned communities (condominiums, townhomes, senior centers), to name a few. Accurate prior (to construction) estimates of the energy savings in these projects reduce risk, decrease financing costs, and help avoid post-construction disputes over performance contract baseline adjustments. This paper demonstrates an improved method of estimating energy savings before construction takes place. Using an engineering model calibrated to pre-construction energy-use data collected in the field, this method is able to predict actual energy savings to a high degree of accuracy. This is verified with post-construction energy-use data from a geothermal heat pump ESPC at Fort Polk, Louisiana. ...

1998-10-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

321

The Power Industry Reform and the lesson from California Situation

Energy savings performance contracting (ESPC) is now receiving greater attention as a means of implementing large-scale energy conservation projects in housing. Opportunities for such projects exist for military housing, federally subsidized low-income housing, and planned communities (condominiums, townhomes, senior centers), to name a few. Accurate prior (to construction) estimates of the energy savings in these projects reduce risk, decrease financing costs, and help avoid post-construction disputes over performance contract baseline adjustments. This paper demonstrates an improved method of estimating energy savings before construction takes place. Using an engineering model calibrated to pre-construction energy-use data collected in the field, this method is able to predict actual energy savings to a high degree of accuracy. This is verified with post-construction energy-use data from a geothermal heat pump ESPC at Fort Polk, Louisiana. ...

1998-01-01

322

Technical data analysis program. Final report. [Fort Lewis and P-99; data consolidation

What kind of lesson do we get from California situation? The first is that the sufficient investment to the operational regulation should be prepared as a system. It is necessary to introduce the systems related to capacity, such as the capacity market system that makes retail suppliers secure the fixed rate of their running peak-load as reserve capacity and other system that secure the 5-year supply capacity by a contract, in which suppliers can pay the penalty if they purchase more capacity than in the contract. The second is that the supplementary measures should be systematized for the supply system not to be in a panic in a case of the shortage situation of equipment. The exchange authority should control the regular inspection program on generators to reduce the market control of the supply companies. Through the supplementary system, the increase of electricity price must make the demand decrease. According to the current plan, it will ...

2001-03-01

323

On the change of pore distribution in the course of coking and its effect on the gap tensile strength and the modulus of elasticity of coke. Zur Veraenderung der Porenverteilung im Verlauf der Verkokung und deren Auswirkung auf die Spaltzugfestigkeit und den Elastizitaetsmodul von Koksen

Separate comprehensive final reports on the status of the SRC-II Demonstration Plant Design and on operating experiences at the Ft. Lewis and P-99 SRC pilot plants were prepared after the termination of those projects. However, time constraints made it impossible to consolidate all of the pilot plant data and operating experiences and relate these to the Demonstration Plant or future plant design. Most of the experimental programs during the later stages of pilot plant operation were in direct support of specific technical uncertainties identified in design work. The results of these programs would have been of substantial use in verifying or modifying design philosophy had the project proceeded. This technical data analysis project was undertaken to consolidate the pilot plant results presented in numerous reports under DOE Contract DE-AC01-79ET10104 for operation of the pilot plants, and to relate these results to specific Demonstration Plant uncertainties. The ...

1984-11-01

324

Laser-assisted solar cell metallization processing. Quarterly report, March 13-June 12, 1984

A model describes the effect of changes to the pore structure on the mechanical properties of semi-coke during coking. The gap tensile experiment makes it possible to determine the mechanical properties of the coke and semi-coke; a theoretical analysis is valid for the deformation of samples in the gap tensile test, by which the gap tensile strength of the coke can be determined, and by which a method for the simultaneous determination of the effective modulus of elasticity was developed. The effect of the pore structure on the mechanical properties is given in semi-empirical equations. The main point here is to check whether a pore in the coke can be regarded as a Griffith crack, and whether the interaction of pores can be neglected. A model which takes the pore distribution into account was also developed and tested. A model for the change of pore structure during coking, which includes the contraction of the semi-coke, and which presupposes a difference in ...

1984-01-01

325

Laser-assisted solar cell metallization processing. Quarterly report, December 13, 1983-March 12, 1984

Laser-assisted processing techniques, utilized to produce fine, metal grid patterns for high-efficiency solar cells, are being investigated, developed, and characterized. The work performed in the third quarter of this contract is detailed here. A preliminary economic evaluation has yielded the conclusion that laser-assisted pyrolysis of spun-on silver neodecanoate is the most promising of all the metallization techniques being investigated in this contract. Early adhesion problems have been solved by optimizing deposition parameters. Linewidth studies have been carried out as a function of laser power, scan speed, and film thickness. Preliminary solar cells have been fabricated and characterized using this metallization scheme. Silver neodecanoate films have also been decomposed using a pulsed uv laser and metal mask. A detailed study of the various models of localized surface temperature rise in silicon due to laser heating has been carried ...

1984-08-20

326

Kinetic aspects of the photolysis of in-station airborne methyl iodide

The aim of this contract is to investigate, develop, and characterize laser-assisted processing techniques utilized to produce the fine-line, thin-metal grid structures that are required to fabricate high-efficiency solar cells. During the first quarter of this contract, a comprehensive literature search was carried out in the various state-of-the-art laser-assisted techniques for metal deposition, including laser chemical vapor deposition and laser photolysis of organometallics, as well as laser-enhanced electroplating. A compact system for the experiments involving laser-assisted photolysis of gas-phase compounds was designed and constructed. The work performed in the second quarter is detailed in this report. Metal deposition experiments have been carried out utilizing laser-assisted pyrolysis of a variety of metal-bearing polymer films and metallo-organic inks spun onto silicon substrates. Laser decomposition of spun-on silver neodecanoate ...

1984-04-03

327

IAEA RESEARCH CONTRACTS SECOND ANNUAL REPORT. Technical Reports Series No. 9

A method for converting organic iodides to elemental iodine would be advantageous in improving the performance of charcoal filters for the removal of radio iodines from reactor off gases. A photochemical method has been developed. The HAVCHM code was used to establish the relevant process time scales on a complete set of rate equations describing the primary and secondary reactions occurring in a plug-flow reactor containing low levels of elemental iodine and methyl iodide in air, which is irradiated by intense u.v. light. These simulations were used to justify the contraction of the complete set of reactions to the most significant elementary processes. The contracted set of rate equations are then solved analytically to render the concentration-time profiles of methyl iodide, total inorganic iodine and total oxidized organics, consistent with the achievement of a desirable radioiodine decontamination factor. For the short contact times ...

328

Development and testing of commercial-scale, coal-fired combustion systems, Phase 3. Technical progress report, October 1990--December 1990

Summaries are presented for those research contracts which expired between December 31, 1960 and December 31, 1981. Topics covered include: factors controlling distribution of fission products in biosphere, non-destructive methods of evaluating the U/sup 235/ and Pu content of irradiated fuel elements, studies of contamination in local marine resources, tracer studies of anemia, non-destructive analysis of irradiated fuel elements using a flux integrating monitor, mechanism of proteolysis of I/sup 131/-labeled fibrinogen, radiosensitivity of spermatogonia of Drosophila melel elements by gamma scanning, uptake and loss of radioactive material by marine bacteria, factors which influence the movement of radioactive strontium from soils to plants, biological concentration of fission products in mollusks from water, decay scheme of Tl/sup 210/, calcium balance in metabolic bone disease, development of radioactive drugs with special reference ...

1962-01-01

329

Development and testing of commercial-scale, coal-fired combustion systems, Phase 3

The US Department of Energy`s Pittsburgh Energy Technology Center (PETC) is actively pursuing the development and testing of coal-fired combustion systems for residential, commercial, and industrial market sectors. In response, MTCI initiated the development of a new combustor technology based on the principle of pulse combustion under the sponsorship of PETC (Contract No. AC22-83PC60419). The initial pulse combustor development program was conducted in three phases (MTCI, Development of a Pulsed Coal Combustor Fired with CWM, Phase III Final Report, DOE Contract No. AC22-83PC60419, November 1986). Phase I included a review of the prior art in the area of pulse combustion and the development of pulse combustor design concepts. It led to the conclusion that pulse combustors offer technical and base-of-operation advantages over conventional burners and also indicated favorable economics for replacement of oil- and gas-fired equipment.

1990-12-31

330

Catalyst and reactor development for a liquid-phase Fischer-Tropsch process. Quarterly technical progress report, 1 April 1981-30 June 1981

The US Department of Energy's Pittsburgh Energy Technology Center (PETC) is actively pursuing the development and testing of coal-fired combustion systems for residential, commercial, and industrial market sectors. In response, MTCI initiated the development of a new combustor technology based on the principle of pulse combustion under the sponsorship of PETC (Contract No. AC22-83PC60419). The initial pulse combustor development program was conducted in three phases (MTCI, Development of a Pulsed Coal Combustor Fired with CWM, Phase III Final Report, DOE Contract No. AC22-83PC60419, November 1986). Phase I included a review of the prior art in the area of pulse combustion and the development of pulse combustor design concepts. It led to the conclusion that pulse combustors offer technical and base-of-operation advantages over conventional burners and also indicated favorable economics for replacement of oil- and gas-fired equipment.

1990-01-01

331

Braking system for use with an arbor of a microscope

In October 1980, Air Products and Chemicals, Inc. began a three year contract with the DOE: Catalyst and Reactor Development for a Liquid Phase Fischer-Tropsch Process. The program contains four major tasks: (1) Project Work Plan, (2) Slurry Catalyst Development, (3) Slurry Reactor Design Studies, and (4) Pilot Facility Design. This report describes work on Tasks 2 and 3 carried out in the third quarter of the contract. In Task 2, the computerized search of the Fischer-Tropsch literature was continued, and improvements were made in data processing programs. Shakedown tests were completed on the first 300 ml slurry reactor, and construction of the second and third reactors began. Five modified conventional slurry catalysts were prepared, and two batches were tested in the gas phase giving information on selectivity as a function of composition and activation. Four supported cluster catalyst were synthesized, and seven were tested in the gas ...

1981-07-01

332

Status and Challenges of the LHC Construction

A balanced braking system comprising a plurality of braking assemblies located about a member to be braked. Each of the braking assemblies consists of a spring biased piston of a first material fitted into a body of a different material which has a greater contraction upon cooling than the piston material. The piston is provided with a recessed head portion over which is positioned a diaphragm and forming a space therebetween to which is connected a pressurized fluid supply. The diaphragm is controlled by the fluid in the space to contact or withdraw from the member to be braked. A cooling device causes the body within which the piston is fitted to contract more than the piston, producing a tight shrink fit therebetween. The braking system is particularly applicable for selectively braking an arbor of an electron microscope which immobilizes, for example, a vertically adjustable low temperature specimen holder during observation. The system ...

333

Sod peat harvesters - results of time and yield research in summer 1986

The LHC is designed to provide proton beams of 7 TeV and nominal luminosity of 10**34 cm**-2s**-1. This objective is achieved at an affordable cost by pushing all major collider components to the limits of technology, by upgrading the existing CERN accelerators and infrastructure, and by involving the technical expertise, resources and dedication of accelerator laboratories world-wide. Following a decade of intensive R&D and technical validation of major collider systems, the LHC construction is now fully underway. Major industrial contracts have been awarded and are in execution for the procurement of the magnet, cryogenics and other systems. In this report, the status of the design and construction of the major LHC systems is presented.

2001-01-01

334

Satellite power systems (SPS) concept definition study (exhibit D). Volume 5: systems engineering/integration research and technology. Final report

More efficient and safe production machines are required for sod peat production. The efficiency and durability of machines is especially important in contract work. Two sod peat harvester types, Pala-14 and Turve-Unsa, were tested by the forest department of the Work Efficiency Associationin summer 1986. Sod peat was collected with these machines at three sod peat production sites. The yield of the Pala-14 harvester was 121 m/sup 3//h for harvesting time, and 56 m/sup 3//h for worksite time, and that of Turve-Unsa was 108 m/sup 3//h and 55 m/sup 3//h, respectively.

1986-01-01

335

Radiological assessment of past, present and potential sources to environmental contamination in the Southern Urals and strategies for remedial measures (SUCON)

Guidelines and ground rules followed in the development of requirements for the SPS are presented. Development planning objectives are specified in each of these areas, and evolutionary SPS program scenarios are described for the various concepts studied during the past one year contract. Program descriptions are presented as planning packages of technical tasks, and schedule phasing. Each package identifies the ground based technology effort that will facilitate SPS definitions, designs, development, and operations.

1981-03-01

336

Quenched large deviations for random walk in a random environment

This report summarises work done on the SUCON Project during 1996-1999 (European Commission Contract No. FI4C-CT95-0001). The project has focused on three major objectives: 1) An assessment of the radiological consequences of the contamination of the South Urals and the Ob river system from the production of plutonium at 'Mayak', 2) The development of models to calculate doses to individuals and populations in the South Urals using environmental data, and 3) The intercomparison, harmonisation and standardisation of techniques used in dose reconstruction and specification of good practice in particular with regard to remedial measures. (au)

2000-12-01

337

Progress in construction of the LHC

We take the point of view of a particle performing random walk with bounded jumps on Z^d in a stationary and ergodic random environment. We prove the quenched large deviation principle (LDP) for the pair empirical measure of the environment Markov chain. By the contraction principle, we deduce the quenched LDP for the mean velocity of the particle and obtain a variational formula for the corresponding rate function. We propose an Ansatz for the minimizer of this formula. We verify this Ansatz for nearest-neighbor walks on Z. As a separate result, we give a probabilistic formula for the ergodic invariant density of the environment Markov chain in the case of ballistic random walk with bounded jumps on Z.

2008-01-01

338

Performance expectation plan

The Large Hadron Collider (LHC) project, approved by the CERN Council in December 1994, has now fully entered its construction phase, with the detailed technical definition of the major systems, and the adjudication of a number of large procurement contracts. We first recall the main features and characteristics of the LHC, report on the advances in definition of the layout and optics as well as on preparation of the injector complex, and review recent progress in the key technical systems of the main ring: magnets, cryogenics and vacuum, as well as civil construction, which has started following acceptance by authorities in the Host States.

1998-01-01

339

Laser-assisted solar cell metallization processing

This document outlines the significant accomplishments of fiscal year 1998 for the Tank Waste Remediation System (TWRS) Project Hanford Management Contract (PHMC) team. Opportunities for improvement to better meet some performance expectations have been identified. The PHMC has performed at an excellent level in administration of leadership, planning, and technical direction. The contractor has met and made notable improvement of attaining customer satisfaction in mission execution. This document includes the team`s recommendation that the PHMC TWRS Performance Expectation Plan evaluation rating for fiscal year 1998 be an Excellent.

1998-09-04

340

International Water Power and Dam Construction Handbook 1993

In this contract, Laser-assisted processing techniques for producing high-quality solar cell metallization patterns are being investigated, developed, and characterized. The tasks comprising these investigations are outlined. Four new batches of solar cells were processed, in addition to several test runs on wafers, using the laser decomposition of spun-on silver neodecanoate to metallize cells. Decomposition of silver neodecanoate was carried out at different laser powers on different cells on a given wafer to determine whether this would have any effect on cell performance. A one watt laser power gave an electroplated linewidth of 50 microns , while at 8 watts the line width was 90 microns.

1986-01-01

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341

Interim report for the Energy Engineering Analysis Program (EEAP), Europe at the Mannheim Military Community, volume 1: Executive summary. Interim report

In this handbook, technical reports on a number of hydro plants under construction are provided. In addition tables of compiled data are presented on a world-wide basis for the following: turbine and hydro generator contracts; hydropower resource potential and development; pumped storage plants; the major dams and hydro plants; roller compacted concrete dams and concrete faced rockfill dams; small hydropower. An address database of international organizations of relevance to hydropower development, national power authorities and nation committees of the International Commission an Large Dams is included. A final and major section of the handbook is a buyer's guide providing extensive company data and information on products and services. (UK)

1993-01-01

342

Hermetically sealed aluminum electrolytic capacitor

Contract No. DACA 90-8l-C-oo72 directs that a basewide energy study be accomplished for the Mannheim and Pirmasens Military Communities, Federal Republic of Germany. The project is identified as Energy Engineering Analysis Program (EEAP) Package No. 5. The overall objective of the study is to produce a systematic plan of improvement projects that will reduce by 1985 the energy consumption in compliance with the Army Facilities Energy Plan without decreasing the readiness posture of the Army.

1984-05-01

343

GT13E gas turbines to power Killingholme A GTCC [gas turbine combined-cycle] plant

Aluminum electrolytic capacitors are presently not allowed on NASA missions because they outgas water and organic vapors, as well as H2. As a consequence, much larger and heavier packages of tantalum capacitors are used. A hermetically sealed aluminum capacitor has been developed under NASA-MSFC SBIR contracts. This capacitor contains a nongassing electrolyte that was developed for this application so internal pressure would remain low. Capacitors rated at 250 to 540 V have been operated under full load for thousands of hours at 85 and 105 C with good electrical performance and low internal pressure. Electrolyte chemistry and seal engineering concepts will be discussed.

1995-04-01

344

Fundamental investigation of duct/ESP phenomena. Final report

National Power is building its first gas turbine combined cycle power station at Killingholme, situated to the south of the River Humber in the East of England. NEI ABB Gas Turbines Limited was awarded the turnkey contract in July 1990 to build a nominal 650 MW combined cycle power station based around three Asea Brown Boveri GT13E gas turbines. The project is outlined in this article. The plant is due for completion in July 1993. (author)

1993-01-01

345

Fundamental investigation of duct/ESP phenomena

Radian Corporation was contracted to investigate duct injection and ESP phenomena in a 1.7 MW pilot plant constructed for this test program. This study was an attempt to resolve problems found in previous studies and answer remaining questions for the technology using an approach which concentrates on the fundamental mechanisms of the process. The goal of the study was to obtain a better understanding of the basic physical and chemical phenomena that control: (1) the desulfurization of flue gas by calcium-based reagent, and (2) the coupling of an existing ESP particulate collection device to the duct injection process. Process economics are being studied by others. (VC)

1991-10-21

346

Fluidic controls for the NERVA engine. Fourth semiannual progress report, November 1969--April 1970

Radian Corporation was contracted to investigate duct injection and ESP phenomena in a 1.7 MW pilot plant constructed for this test program. This study was an attempt to resolve problems found in previous studies and answer remaining questions for the technology using an approach which concentrates on the fundamental mechanisms of the process. The goal of the study was to obtain a better understanding of the basic physical and chemical phenomena that control: (1) the desulfurization of flue gas by calcium-based reagent, and (2) the coupling of an existing ESP particulate collection device to the duct injection process. Process economics are being studied by others. (VC)

1991-10-21

347

Fission-track study of the uranium bio-geochemistry in carbonates of Bikini and Enewetak Atolls. Progress report, July 1, 1974--December 31, 1975

Development progress of the full-flow engine fluidic control system is reported. The fluidic temperature control subsystem was transferred from IR and D status to the SNP-1 program contract 1 December 1969. Several new fluidic control concepts were explored either experimentally or analytically. Basic component and subsystem design data at simulated engine state-point conditions were secured. Component design effort during the next six months will include fabrication and simulated tests of selected ''breadboard'' configurations. (auth).

348

Fission-track study of the uranium bio-geochemistry in carbonates of Bikini and Enewetak Atolls. Progress report, July 1, 1974--December 31, 1975

Major contributions during this contract period have been in developing an analytical procedure for Pu measurement, and in applying the developed procedures to determining the plutonium concentration and distribution in coral from the Bikini Atoll. In conjunction with these contributions, measurements using the fission-track method have been made of the uranium distribution and concentrations in several carbonate samples from drill cores obtained from the Runit Island Enewetak Atoll. Petrographic studies on these drill core samples have been made to correlate the uranium data with the mineralogical data.

349

Estimating deficit probabilities with price-responsive demand in contract-based electricity markets

Major contributions during this contract period have been in developing an analytical procedure for Pu measurement, and in applying the developed procedures to determining the plutonium concentration and distribution in coral from the Bikini Atoll. In conjunction with these contributions, measurements using the fission-track method have been made of the uranium distribution and concentrations in several carbonate samples from drill cores obtained from the Runit Island Enewetak Atoll. Petrographic studies on these drill core samples have been made to correlate the uranium data with the mineralogical data. (auth)

1975-09-01

350

Energy policy: security of supply, sustainability and competition

Studies that estimate deficit probabilities in hydrothermal systems have generally ignored the response of demand to changing prices, in the belief that such response is largely irrelevant. We show that ignoring the response of demand to prices can lead to substantial over or under estimation of the probability of an energy deficit. To make our point we present an estimation of deficit probabilities in Chile's Central Interconnected System between 2006 and 2010. This period is characterized by tight supply, fast consumption growth and rising electricity prices. When the response of demand to rising prices is acknowledged, forecasted deficit probabilities and marginal costs are shown to be substantially lower. (author)

2009-02-01

351

ENGINEERING DEVELOPMENT OF CERAMIC MEMBRANE REACTOR SYSTEM FOR CONVERTING NATURAL GAS TO HYDROGEN AND SYNTHESIS GAS FOR LIQUID TRANSPORTATION FUELS

The paper considers the main components of energy policy, in particular the challenges of network security of supply, long-term contracts and the environmental constraints. It is argued that the United Kingdom's energy policy should take account of multiple market failures and context dependent. Given energy liberalisation in the 1980s and 1990s, it is argued that interventions based upon market-based instruments should be given greater importance. Institutional reform to reflect the shift in focus towards investment in non-carbon technologies and the security issues associated with networks is proposed, notably the creation of an energy agency. 15 refs., 2 figs.

2002-02-01

352

ENGINEERING DEVELOPMENT OF CERAMIC MEMBRANE REACTOR SYSTEM FOR CONVERTING NATURAL GAS TO HYDROGEN AND SYNTHESIS GAS FOR LIQUID TRANSPORTATION FUELS

The objective of this contract is to research, develop and demonstrate a novel ceramic membrane reactor system for the low-cost conversion of natural gas to synthesis gas and hydrogen for liquid transportation fuels: the ITM Syngas process. Through an eight-year, three-phase program, the technology will be developed and scaled up to obtain the technical, engineering, operating and economic data necessary for the final step to full commercialization of the Gas-to-Liquids (GTL) conversion technology. This report is a summary of activities through February 1999.

1999-03-01

353

Development of a retrofit coal combustor for industrial applications. Technical progress report, January--March 1987

The objective of this contract is to research, develop and demonstrate a novel ceramic membrane reactor system for the low-cost conversion of natural gas to synthesis gas and hydrogen for liquid transportation fuels: the ITM Syngas process. Through an eight-year, three-phase program, the technology will be developed and scaled up to obtain the technical, engineering, operating and economic data necessary for the final step to full commercialization of the Gas-to-Liquids (GTL) conversion technology. This report is a summary of activities through September 1999.

1999-10-01

354

Cosmic no hair for collapsing universes

In this first quarterly technical report for DOE Contract No. DE-AC22-87PC79654, a description of the background, technology, and application is provided. The design and fabrication of advanced combustion chambers were completed during this period. Initial testing on both the bare metal and refractory lined advanced chambers were initiated. The units were tested initially with gas but primarily with coal. A Pittsburgh No. 8 pulverized coal was used for these test activities. Both advanced chambers pulsed well.

1987-12-31

355

Controlling transit-bus emissions and improving management

It is shown that all contracting, spatially homogeneous, orthogonal Bianchi cosmologies that are sourced by an ultra-stiff fluid with an arbitrary and, in general, varying equation of state asymptote to the spatially flat and isotropic universe in the neighbourhood of the big crunch singularity. This result is employed to investigate the asymptotic dynamics of a collapsing Bianchi type IX universe sourced by a scalar field rolling down a steep, negative exponential potential. A toroidally compactified version of M*-theory that leads to such a potential is discussed and it is shown that the isotropic attractor solution for a collapsing Bianchi type IX universe is supersymmetric when interpreted in an 11-dimensional context.

2006-05-21

356

Coal export financing: how it is done and who does it. (From the series, Market Guide for Steam Coal Exports from Appalachia)

The 8 papers in the report deal with the following areas: Introduction to diesel particulate emissions, alternative fuels, and the transit industry; Technical problems and policy issues associated with the 1991 bus emissions standards; Reducing transit bus emissions: comparative costs and benefits of methanol, particulate traps, and fuel modification; Effects of applying emissions averaging, trading, and banking to transit buses; Strategic review of heavy-duty engine emission regulations and alternate fuels; Meeting bus emissions standards--a perspective; Economic evaluation of bus maintenance contracting; Objectives for a transit-bus-fleet management data, information, and knowledge exchange.

1988-01-01

357

Chemiluminescence of polymers: applications to weapons materials

This publication, part of the series titled Market Guide for Steam Coal Exports from Appalachia provides information on export markets, contracts, and related matters for producers and others involved in mining, selling, and shipping Appalachian coal to foreign buyers. It also includes information on the financial institutions that provide export finance and how they are used. Senior officers of more than 40 banks ranged from the largest money center bank and a major foreign bank in New York City to small banks in Appalachia.

1982-11-01

358

CLIMATE CHANGE FUEL CELL PROGRAM UNITED STATES COAST GUARD AIR STATION CAPE COD BOURNE, MASSACHUSETTS

An apparatus was designed and built for the purpose of exposing samples of solid polymers to varying temperatures, atmospheres and stress levels while quantitatively recording the resulting chemiluminescence. Preliminary data were acquired with this apparatus that show a correlation between an enhanced chemiluminescence signal at a low level of applied stress and a decrease in tensile strength for the most commonly used epoxy resin in high performance fiber composites, TGMDA DDS. The studies with cellular silicone cushions (which are used to accommodate thermal expansion and contraction) have defined the temperature regimes in which accelerated aging tests are valid for extrapolation to ambient temperature. Preliminary data on Kevlar fibers is also discussed.

1984-06-01

359

Botulinum toxin—Beyond wrinkles

This report covers the first year of operation of a fuel cell power plant, installed by PPL Spectrum, Inc. (PPL) under contract with the United States Coast Guard (USCG), Research and Development Center (RDC). The fuel cell was installed at Air Station Cape Cod in Bourne, MA. The project had the support of the Massachusetts Technology Collaborative (MTC), the Department of Energy (DOE), and Keyspan Energy. PPL selected FuelCell Energy, Inc. (FCE) and its fuel cell model DFC{reg_sign}300 for the contract. Grant contributions were finalized and a contract between PPL and the USCG for the manufacture, installation, and first year's maintenance of the fuel cell was executed on September 24, 2001. As the prime contractor, PPL was responsible for all facets of the project. All the work was completed by PPL through various subcontracts, including the primary subcontract with FCE for the manufacture, delivery, and ...

2004-06-30

360

British Library Electronic Table of Contents (United Kingdom)

Botulinum neurotoxin is produced by the bacterium, Clostridium botulinum. The neurotoxin inhibits acetylcholine at the neuromuscular junction, thus interfering with overall muscular contraction. Botulinum neurotoxin is commonly used for the following medical conditions: cervical dystonia, upper limb spasticity, blepharospasm, strabismus, and hyperhydrosis. However, the use of botulinum neurotoxin was recently approved for the prophylaxis of headaches in adults with chronic migraines. The proposed mechanism of botulinum neurotoxin is no longer solely limited to the inhibition of acetylcholine. There are new mechanisms emerging that involve inhibition of proinflammatory agents and neuropeptides involved in chronic pain. Consequently, there is a disruption of the overall sensory feedback loop...

2011-01-01

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361

Acceptance test of full scope simulator of Daya Bay NPP

AAR in concrete of Asejire spillway (OYO state - Nigeria)

The author describes the purpose, classification and main process of acceptance test of full scope simulator of Daya Bay Nuclear Power Plant, including the correction of non-conformance items which are discovered during the performance of acceptance tests. The results of the acceptance tests show that the model accepted by the full scope simulator of Daya Bay Nuclear Power Plant is fully able to cope with the simulation of normal transients and incidental transients and the performance of the simulator indeed compiled with the technical specifications which are defined n the relevant contracts.

362

2001 evaluation of juvenile fall chinook stranding on the Hanford Reach of the Columbia River.; TOPICAL

The Asejire dam at Ibadan, Nigeria was constructed in the late sixties for the purpose of providing water for the city of Ibadan (presently about 4,5 million inhabitants). It is located on the Oshun river approximately fifteen miles from the city. In 1982 cracks were observed on the wing walls and although these continued to develop, no attempt was made at that time to investigate their causes and no repair was carried out. In 1989 the SGI ENGINEERING Group of Geneva, Switzerland was appointed as the consultant for the complete refurbishment of the Asejire water scheme. The consortium Degremont-Poat-Clemessy was awarded the contract for the project. The African Development Bank and the Nigerian Government have provided the loan to finance the project.

1995-12-31

363

2000 evaluation of juvenile fall chinook stranding on the Hanford Reach of the Columbia River.; TOPICAL

The Washington Department of Fish and Wildlife (WDFW) has been contracted through the Bonneville Power Administration (BPA) and the Grant County Public Utility District (GCPUD) to perform an evaluation of juvenile fall chinook salmon (Oncorhynchus tshawytscha) stranding on the Hanford Reach of the Columbia River. The evaluation, in the fifth year of a multi-year study, has been developed to assess the impacts of water fluctuations from Priest Rapids Dam on rearing juvenile fall chinook salmon, other fishes, and benthic macroinvertebrates of the Hanford Reach. This document provides the results of the 2001 field season.

364

1999 evaluation of juvenile fall chinook stranding on the Hanford Reach of the Columbia River, annual report 1999.; ANNUAL

The Washington Department of Fish and Wildlife (WDFW) has been contracted through the Bonneville Power Administration (BPA) and the Grant County Public Utility District (GCPUD) to perform an evaluation of juvenile fall chinook salmon (Oncorhynchus tshawytscha) stranding on the Hanford Reach. The evaluation, in the fourth year of a multi-year study, has been developed to assess the impacts of water fluctuations from Priest Rapids Dam on rearing juvenile fall chinook salmon, other fishes, and benthic macroinvertebrates of the Hanford Reach. This document provides the results of the 2000 field season.

365

1998 evaluation of juvenile fall chinook salmon stranding on the Hanford Reach of the Columbia River.; TOPICAL

The Washington Department of Fish and Wildlife (WDFW) has been contracted through the Bonneville Power Administration (BPA) and the Grant County Public Utility District (GCPUD) to perform an evaluation of juvenile fall chinook salmon (Oncorhynchus tshawytscha) stranding on the Hanford Reach. The evaluation, in the third year of a multi-year study, has been developed to assess the impacts of water fluctuations from Priest Rapids Dam on rearing juvenile fall chinook salmon, other fishes, and benthic macroinvertebrates of the Hanford Reach. This document provides the results of the 1999 field season.

366

Rapid inhibition of vasoconstriction in renal afferent arterioles by aldosterone

The Washington Department of Fish and Wildlife (WDFW) has been contracted through the Bonneville Power Administration (BPA) and the Grant County Public Utility District (GCPUD) to perform an evaluation of juvenile fall chinook salmon (Oncorhynchus tshawytscha) stranding on the Hanford Reach. The evaluation, in the second year of a multi-year study, has been developed to assess the impacts of water fluctuations from Priest Rapids Dam on rearing juvenile fall chinook salmon, other fish species, and benthic macroinvertebrates of the Hanford Reach. This document provides the results of the 1998 field season.

367

Aldosterone has been suggested to elicit vessel contraction via a nongenomic mechanism. We tested this proposal in microdissected, perfused rabbit renal afferent arterioles. Aldosterone had no effect on internal diameter in concentrations from 10(-10) to 10(-5) mol/L, but aldosterone abolished the ability of 100 mmol/L KCl to induce vascular contraction. The inhibitory effect of aldosterone was observed from 1 pmol/L. The inhibitory effect was significant after 5 minutes and maximal after 20 minutes and was fully reversible. Actinomycin D (10(-6) mol/L) prolonged the effect of aldosterone. The effect was abolished by the mineralocorticoid receptor antagonist spironolactone (10(-7) mol/L) but not by the glucocorticoid receptor antagonist mifepristone (10(-6) mol/L). The K+-mediated increase of intracellular calcium concentration in afferent arterioles was not affected by aldosterone. Mineralocorticoid receptor was detected by reverse ...

2003-01-01

368

New drilling rigs

Geothermal Heat Pump Profitability in Energy Services

Friede and Goldman Ltd. of New Orleans, Louisiana has a successful drilling rig, the L-780 jack-up series. The triangular-shaped drilling vessel measures 180 x 176 ft. and is equipped with three 352 ft legs including spud cans. It is designed to work in up to 250 ft waters and drill to 20,000 ft depths. The unit is scheduled to begin initial drilling operations in the Gulf of Mexico for Arco. Design features are included for the unit. Davie Shipbuilding Ltd. has entered the Mexican offshore market with the signing of a $40,000,000 Canadian contract for a jack-up to work in 300 ft water depths. Baker Marine Corporation has contracted with the People's Republic of China for construction of two self-elevating jack-ups. The units will be built for Magnum Marine, headquartered in Houston. Details for the two rigs are given. Santa Fe International Corporation has ordered a new jack-up rig to work initially in the Gulf of Suez. The newly ...

1981-02-01

369

Development of the integrated environmental control model. Technical progress report, [October 1--December 31, 1992

If geothermal heat pumps (GHPs) are to make a significant mark in the market, we believe that it will be through energy service pricing contracts offered by retailcos. The benefits of GHPs are ideally suited to energy service pricing (ESP) contractual arrangements; however, few retailcos are thoroughly familiar with the benefits of GHPs. Many of the same barriers that have prevented GHPs from reaching their full potential in the current market environment remain in place for retailcos. A lack of awareness, concerns over the actual efficiencies of GHPs, perceptions of extremely high first costs, unknown records for maintenance costs, etc. have all contributed to limited adoption of GHP technology. These same factors are of concern to retailcos as they contemplate long term customer contracts. The central focus of this project was the creation of models, using actual GHP operating data and the experience of seasoned professionals, to simulate the ...

1997-11-01

370

Development of the integrated environmental control model

In its current configuration, the IECM provides a capability to model various conventional and advanced processes for controlling air pollutant emissions from coalfired power plants before, during, or after combustion. The principal purpose of the model is to calculate the performance, emissions, and cost of power Plant configurations employing alternative environmental control methods. The model consists of various control technology modules, which may be integrated into a complete utility plant in any desired combination. in conuwt to conventional deterministic models, the IECM offers the unique capability to assign probabilistic values to all model input parameters, and to obtain probabilistic outputs in the form of cumulative distribution functions indicating the likelihood of different costs and performance results. The most recent version of the IECM, implemented on a Macintosh II computer and containing a number of software and model enhancements, was delivered to DOE/PETC at ...

1993-01-01

371

Nodular fasciitis: correlation of MRI findings and histopathology

In its current configuration, the IECM provides a capability to model various conventional and advanced processes for controlling air pollutant emissions from coalfired power plants before, during, or after combustion. The principal purpose of the model is to calculate the performance, emissions, and cost of power Plant configurations employing alternative environmental control methods. The model consists of various control technology modules, which may be integrated into a complete utility plant in any desired combination. in conuwt to conventional deterministic models, the IECM offers the unique capability to assign probabilistic values to all model input parameters, and to obtain probabilistic outputs in the form of cumulative distribution functions indicating the likelihood of different costs and performance results. The most recent version of the IECM, implemented on a Macintosh II computer and containing a number of software and model enhancements, was delivered to DOE/PETC at ...

1993-01-01

372

Synthesis and biodistribution of a novel 99mTc-DMSA-metronidazole ester as a potential tumor hypoxia imaging agent

Objective: To compare the histopathology of nodular fasciitis (NF) with the magnetic resonance imaging (MRI) findings in order to evaluate the basis of the MR signal characteristics. Design and patients: Ten patients with NF, nine females and 1 male, with an age ranging from 13 to 58 years (mean 26.8 years) were studied. MRI findings, available in all 10 patients, were compared with the histopathology in nine patients, and an area-to-area comparative study of the whole specimen section histopathology and MRI was performed in two patients. Results: On the basis of an excisional biopsy or resection specimen, the nine lesions were classified into myxoid (n=4), cellular (n=3) and fibrous (n=2) subtypes. Four myxoid lesions with a subcutaneous location showed a homogeneous SI comparable with muscle on T1-weighted images, high SI on T2-weighted images, and had homogeneous enhancement. One cellular lesion presented with homogeneous, slightly higher SI than ...

2002-03-01

373

British Library Electronic Table of Contents (United Kingdom)

The dimercaptosuccinic acid metronidazole ester (DMSAMe) was synthesized and radiolabeled with 99mTc to form the 99mTc-DMSAMe complex in high yield. The radiochemical purity of the 99mTc-DMSAMe complex was over 90%, as measured by TLC and by HPLC, without any notable decomposition at room temperature over a period of 6?h. Its partition coefficient indicated that it was a lipophilic complex. The tumor cell experiment and the biodistribution in mice bearing S 180 tumor showed that the 99mTc-DMSAMe complex had a certain hypoxic selectivity and accumulated in the tumor with high uptake and good retention. The tumor/blood and tumor/muscle ratios increased with time, suggesting it would be a possible tumor hypoxia imaging agent.

2010-01-01

374

Synthesis and biodistribution of "9"9"mTc-peptides conjugated adenine as tumor imaging agents

British Library Electronic Table of Contents (United Kingdom)

Two peptide ligands conjugated adenine, [9-N-(tritylmercapto acetyl diglycyl aminoethyl) adenine, Tr-MAG_2-Ade] and [9-N-(tritylmercapto acetyl triglycyl aminoethyl) adenine, Tr-MAG3-Ade], are synthesized and labeled with "9"9"mTc by directly labeling method. The stability of "9"9"mTc-MAG_2- adenine and "9"9"mTc-MAG_3-adenine in vitro is measured. The uptake radios of tumor to muscle at 3h post-injection are 5.70 and 4.92, respectively. The biodistribution and scintigraphic imaging studies show that the two complexes have high localization in tumor and high contrasted tumor images can be obtained, which suggest their potential utility as tumor imaging agents. But the high radioactivity of abdomen could prevent the tumor imaging in this area. (author)

2007-07-01

375

PurposeTo conduct a retrospective analysis within a large university teaching hospital, comparing outcomes between patients receiving either radical surgery or radiotherapy as curative treatment for bladder cancer.Patients and MethodsBetween March 1996 and December 2000, 169 patients were treated radically for muscle-invasive bladder cancer. Data were collected from patient notes. Statistical analyses were performed using Kaplan-Meier methods and Cox proportional hazards regression analysis to compare radiotherapy and surgical outcome data.ResultsThere was no difference in overall, cause-specific, and distant recurrence-free survival at 5 years between the two groups, despite the radiotherapy group being older (median age, 75.3 years vs. 68.2 years). There were 31 local bladder recurrences...

2008-01-01

376

Selective Tibial Neurotomy in the Treatment of Spastic Equinovarus Foot in Hemiplegic Patients: A 2-Year Longitudinal Follow-Up of 30 Cases

British Library Electronic Table of Contents (United Kingdom)

Deltombe T, Gustin T. Selective tibial neurotomy in the treatment of spastic equinovarus foot in hemiplegic patients: a 2-year longitudinal follow-up of 30 cases. Objective To assess the long-term efficacy of selective tibial neurotomy in the treatment of spastic equinovarus foot in hemiplegic patients. Design Intervention study (before-after trial) with an observational design and 2-year follow-up. Setting Spasticity group in a university hospital. Participants Hemiplegic patients (N=30) with spastic equinovarus foot. Intervention A selective neurotomy was performed at the level of the motor nerve branches of the tibial nerve. Main Outcome Measures Spasticity (Ashworth scale), muscle strength (Medical Research Council scale), passive ankle dorsiflexion, gait parameters (6 min walking test...

2010-01-01

377

Penile rehabilitation therapy with PDE-V inhibitors following radical prostatectomy: proceed with caution.

Observation of the study of protein metabolism in relation to nutrition

Penile rehabilitation therapy following radical prostatectomy is a much debated topic. Erectile dysfunction is still a significant contributor to postoperative morbidity following radical prostatectomy, despite meticulous nerve-sparing technique. Secondary smooth muscle changes in the penis have been identified as the underlying causes of penile atrophy, veno-occlusive dysfunction, and fibrosis. Initial observations that intracavernous injection therapies used on a regular basis postoperatively resulted in improvements in the return of spontaneous erectile function led to the development of penile rehabilitation protocols. Chronic dosing of PDE-V inhibitors is now commonly used by urologists after radical prostatectomy. Despite the current enthusiasm of penile rehabilitation therapy, current scientific evidence with clinical trials is still limited. PMID:19255627

2009-01-25

378

Metabolic and molecular stress responses of gilthead seam bream Sparus aurata during exposure to low ambient temperature: an analysis of mechanisms underlying the winter syndrome

It is a useful hypothesis to thing of the reaction to protein deprivation as made up of two parts. First there is an initial adaptation involving rapid losses of protein. This is followed by slow continuing depletion. When considering two organ groups, such as the liver and muscle, it appears that the curve of urinary nitrogen excretion reflects the different parts they play in these two phases. The changes in the relative amounts of protein in different organs results in an alteration in the pattern of body protein at the level of the organ, the tissue and the cell. These changes are themselves the result of altered rates of synthesis and breakdown. The questions that must be asked and hopefully will be answered with the help of isotopes, are how these changes are brought about, how they are inter-related and controlled, and what is their significance? This paper contains a discussion of the few results that have been obtained so far. 1 fig.

1965-06-01

379

British Library Electronic Table of Contents (United Kingdom)

The winter syndrome in the gilthead sea bream Sparus aurata indicates that the species is exposed to critically low temperatures in Mediterranean aquaculture in winter. The present study of metabolic patterns and molecular stress responses during cold exposure was carried out to investigate this ?disease?, in light of the recent concept of oxygen and capacity limited thermal tolerance. The metabolic profile of fuel oxidation was examined by determining the activities of the enzymes hexokinase (HK), aldolase (Ald), pyruvate kinase (PK), l-lactate dehydrogenase (l-LDH), citrate synthase (CS), malate dehydrogenase (MDH) and 3-hydroxyacyl CoA dehydrogenase (HOAD) in heart, red and white muscle after exposure to temperatures of 10, 14 and 18?C. Especially, the increase in LDH activity combined ...

2010-01-01

380

MRT for operation planning in anal atresias

Isolation of functional mitochondria from rat kidney and skeletal muscle without manual homogenization

We evaluated in this study the value of preoperative examinations of anal atresia with an optimised MRI strategie. 13 patients with anorectal anomalies, most of them younger than one year, underwent an MRI examination of the pelvis. 10 of these patients were operated afterwards. Compared with the situs shown by the operation the results of the MRI examination were very exact in all cases in respect of the level of atresia and the development of the striateed muscle complex. Fistulas could be completely described in most cases. MRI demonstrated additional lesions in some patients which were of great importance for planning the further treatment of the patients. As a consequence MRI can give valid information on anal atresia for planning the operative treatment. (orig.).

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381

British Library Electronic Table of Contents (United Kingdom)

Isolation of functional and intact mitochondria from solid tissue is crucial for studies that focus on the elucidation of normal mitochondrial physiology and/or mitochondrial dysfunction in conditions such as aging, diabetes, and cancer. There is growing recognition of the importance of mitochondria both as targets for drug development and as off-target mediators of drug side effects. Unfortunately, mitochondrial isolation from tissue is generally carried out using homogenizer-based methods that require extensive operator experience to obtain reproducible high-quality preparations. These methods limit dissemination, impede scale-up, and contribute to difficulties in reproducing experimental results over time and across laboratories. Here we describe semiautomated methods to disrupt tissue ...

2011-01-01

382

Inhibition of the heterotetrameric K++ channel KCNQ1/KCNE1 by the AMP-activated protein kinase

British Library Electronic Table of Contents (United Kingdom)

Abstract The heterotetrameric K++-channel KCNQ1/KCNE1 is expressed in heart, skeletal muscle, liver and several epithelia including the renal proximal tubule. In the heart, it contributes to the repolarization of cardiomyocytes. The repolarization is impaired in ischemia. Ischemia stimulates the AMP-activated protein kinase (AMPK), a serine/threonine kinase, sensing energy depletion and stimulating several cellular mechanisms to enhance energy production and to limit energy utilization. AMPK has previously been shown to downregulate the epithelial Na++ channel ENaC, an effect mediated by the ubiquitin ligase Nedd4-2. The present study explored whether AMPK regulates KCNQ1/KCNE1. To this end, cRNA encoding KCNQ1/KCNE1 was injected into Xenopus oocytes with and without additional injection o...

2011-01-01

383

Hypogonadism in DM1 and its relationship to erectile dysfunction

British Library Electronic Table of Contents (United Kingdom)

Myotonic dystrophy type 1 (DM1) is characterized by both a premature appearance of age-related phenotypes and multiple organ involvement, which affects skeletal and smooth muscle as well as the eye, heart, central nervous system, and endocrine system. Although erectile dysfunction (ED) is a frequent complaint in patients with DM1, it has not been investigated in great depth. Hypogonadism, which is reported to be one of the physical causes of ED in the general population, frequently occurs in DM1. We planned this case?control study to evaluate the relationship between hypogonadism, as defined by the sexual hormone profile (FSH, LH, testosterone (T) and prolactin) and ED, as assessed by means of an internationally validated self-administered questionnaire (IIEF). DM1 patients had significant...

2011-01-01

384

Forkhead box protein P1 as a downstream target of transforming growth factor-b induces collagen synthesis and correlates with a more stable plaque phenotype

British Library Electronic Table of Contents (United Kingdom)

Objective: Atherosclerosis is an inflammatory disease, modulated by plaque stabilizing and de-stabilizing cell populations such as infiltrating monocytes and vascular smooth muscle cells (vSMCs). Transcription factors regulating proliferation and differentiation of atherosclerosis relevant cell types are of interest in this context. The forkhead box transcription factor FoxP1 modulates monocyte differentiation. We studied FoxP1 expression in atherosclerotic tissue, correlated FoxP1 expression with plaque characteristics and identified associations between FoxP1 and plaque proteins. Methods: 116 Atherosclerotic plaques from carotid endarterectomy samples were histologically classified (fibrous, fibroatheromatous, atheromatous) and subjected to semi-quantitative protein analysis. Macrophage,...

2011-01-01

385

Extremum-Preserving Limiters for MUSCL and PPM

Electrophysiological mechanisms of sophocarpine as a potential antiarrhythmic agent

Limiters are nonlinear hybridization techniques that are used to preserve positivity and monotonicity when numerically solving hyperbolic conservation laws. Unfortunately, the original methods suffer from the truncation-error being first-order accurate at all extrema despite the accuracy of the higher-order method. To remedy this problem, higher-order extensions were proposed that relied on elaborate analytic and geometric constructions. Since extremum-preserving limiters are applied only at extrema, additional computational cost is negligible. Therefore, extremum-preserving limiters ensure higher-order spatial accuracy while maintaining simplicity. This report presents higher-order limiting for (i) computing van Leer slopes and (ii) adjusting parabolic profiles. This limiting preserves monotonicity and accuracy at smooth extrema, maintains stability in the presence of discontinuities and under-resolved gradients, and is based on constraining the interpolated values at extrema (and ...

2009-01-01

386

British Library Electronic Table of Contents (United Kingdom)

Aim:To examine the electrophysiological effects of sophocarpine on action potentials (AP) and ionic currents of cardiac myocytes and to compare some of these effects with those of amiodarone.Methods:Langendorff perfusion set-up was used in isolated guinea pig heart, and responses to sophocarpine were monitored using electrocardiograph. Conventional microelectrode, voltage clamp technique and perforated patch were employed to record fast response AP (fAP), slow response AP (sAP) and ionic currents in guinea pig papillary muscle or rabbit sinus node cells.Results:Tachyarrhythmia produced by isoprenaline (15 ?mol/L) could be reversed by sophocarpine (300 ?mol/L). Sophocarpine (10 ?mol/L) decreased the amplitude by 4.0%, maximal depolarization velocity (Vmax) of the fAP by 24.4%...

2011-01-01

387

Development of a pulse control-type MEMS microrobot with a hardware neural network

British Library Electronic Table of Contents (United Kingdom)

This article presents the micro-electro-mechanical systems (MEMS) microrobot which demonstrates locomotion controlled by hardware neural networks (HNN). The size of the microrobot fabricated by the MEMS technology is 4 ? 4 ? 3.5 mm. The frame of the robot is made of silicon wafer, and it is equipped with a rotary-type actuator, a link mechanism, and six legs. The rotary-type actuator generates rotational movement by applying an electrical current to artificial muscle wires. The locomotion of the microrobot is obtained by the rotation of the rotary-type actuator. As in a living organism, the HNN realized robot control without using any software programs, A/D converters, or additional driving circuits. A central pattern generator (CPG) model was implemented as an HNN system to emulate the lo...

2011-01-01

388

Abces du muscle iliopsoas : complication rare de la sacro-iliite a pyogene chez lenfant

British Library Electronic Table of Contents (United Kingdom)

Pyogenic sacroiliitis is a rare entity in children. Diagnosis is often delayed because of its variable clinical presentation, low suspicion by the examining physician, and rare findings on radiographs. Delayed diagnosis, however, results in complications such as iliopsoas abscess. We report the case of a 12-year-old girl hospitalized with a 21-day history of fever, pain in the left iliac fossa, and flexion contracture of the hip. On examination, she had fever (38.9 ^oC), psoitis, localized tenderness at the left sacroiliac joint, and pain elicited by lateral compression of the pelvis. The abdominal examination was normal. The erythrocyte sedimentation rate was 130mm in the first hour, C-reactive protein was 186mg/l, and the white blood cell count was 18,400/mm^3, with 79% neutrophils. Urin...

2010-01-01

389

A simplified method for cholesterol determination in meat and meat products

British Library Electronic Table of Contents (United Kingdom)

The objectives of this study were to develop an accurate and precise method for cholesterol quantification in meat samples based on modifications made to an existing procedure (AOAC Official Method 994.10), and to apply this modified method to evaluate cholesterol levels in longissimus muscles (LM) from Angus (AN, n=5), Brahman (BR, n=4), and Romosinuano (RM, n=9) breeds. Validation of this method was performed using a meat homogenate (Standard Reference Material 1546) from National Institute of Standards and Technology (NIST), and LM samples from the three breeds with fat contents ranging from 2.4% to 9.3%. The results indicated that the modified method was accurate with cholesterol recovery exceeding 95%. The method was also found to be precise with an average coefficient of variation of...

2008-01-01

390

A model of a self-oscillatory process involving elements discretely distributed in space

[Development of efficient DNA isolation procedures for Cryptosporidium and Trichinella PCR detection in fecal samples].

Self-excited oscillations of a distributed medium can be investigated in terms of discrete physical models described by multidimensional systems of nonlinear equations which transform into equations of self-oscillating distributed media as the number of dimensions goes to infinity. Differential equations of such a self-oscillating system are set up and investigated. Coupling between elements of the medium, conditions under which the system constitutes an open system, internal impedance between the energy source and the system elements, and boundary conditions defining open and closed systems are discussed. The Gunn effect, eolian noise, self-oscillations of DNA molecules and of cardiac muscle, and wave processes in the cerebral cortex are mentioned as examples of self-oscillatory processes in question.

1975-01-01

391

Structural determinants of alpha-bungarotoxin binding to the sequence segment 181-200 of the muscle nicotinic acetylcholine receptor #alpha# subunit: Effects of cysteine/cystine modification and species-specific amino acid substitution

PCR detection of genetic material of the parasites present in faeces may be an alternative for microscopic and serological tests routinely used for diagnosing parasitic enteral infections. However, small amount of target DNA combined with low efficiency of total DNA extraction, and presence of PCR inhibitors in the samples to be amplified, may cause false negative detection results. The aim of this work was to evaluate the impact of DNA isolation procedure used on the amplification of DNA fragments from the genomes of protozoan Cryptosporidium parvum and the nematode Trichinella spiralis. Two methods based on different principles of biological material lysis were evaluated; NucliSENS miniMAG employing simultaneously applied chemical lysis and mechanical disruption or mechanical disruption followed by enzymatic lysis in case of QIAamp DNA Stool Mini Kit. Both of the analyzed systems for nucleic acids purification allowed isolation of DNA from purified Cryptosporidium parvum oocysts and ...

2009-01-01

392

Semi-automated segmentation of the sigmoid and descending colon for radiotherapy planning using the fast marching method

The sequence segment 181-200 of the Torpedo nicotinic acetylcholine receptor (nAChR) #alpha#subunit forms a binding site for #alpha#-bungarotoxin (#alpha#-BTX). Synthetic peptides corresponding to the homologous sequences of human, calf, mouse, chicken, frog, and cobra muscle nAChR #alpha#1 subunits were tested for their ability to bind "1"2"5I-#alpha#-BTX, and differences in #alpha#-BTX affinity were determined by using solution (IC_5_0s) and solid-phase (K_ds) assays. Panels of overlapping peptides corresponding to the complete #alpha#1 subunit of mouse and human were also tested for #alpha#-BTX binding, but other sequence segments forming the #alpha#-BTX site were not consistently detectable. The role of a putative vicinal disulfide bound between Cys-192 and -193, relative to the Torpedo sequence, was determined by modifying the peptides with sulfhydryl reagents. Reduction and alkylation of the peptides decreased #alpha#-BTX binding, whereas oxidation of the ...

393

Proteomic Profiling of Mesenchymal Stem Cell Responses to Mechanical Strain and TGF-B1

A fast and accurate segmentation of organs at risk, such as the healthy colon, would be of benefit for planning of radiotherapy, in particular in an adaptive scenario. For the treatment of pelvic tumours, a great challenge is the segmentation of the most adjacent and sensitive parts of the gastrointestinal tract, the sigmoid and descending colon. We propose a semi-automated method to segment these bowel parts using the fast marching (FM) method. Standard 3D computed tomography (CT) image data obtained from routine radiotherapy planning were used. Our pre-processing steps distinguish the intestine, muscles and air from connective tissue. The core part of our method separates the sigmoid and descending colon from the muscles and other segments of the intestine. This is done by utilizing the ability of the FM method to compute a specified minimal energy functional integrated along a path, and thereby extracting the colon centre line between ...

2010-09-21

394

Preparation and biodistribution of yttrium-90 lipiodol in rats following hepatic arterial injection

Mesenchymal stem cells (MSCs) are a potential source of smooth muscle cells (SMCs) for constructing tissue-engineered vascular grafts. However, the details of how specific combinations of vascular microenvironmental factors regulate MSCs are not well understood. Previous studies have suggested that both mechanical stimulation with uniaxial cyclic strain and chemical stimulation with transforming growth factor {beta}1 (TGF-{beta}1) can induce smooth muscle markers in MSCs. In this study, we investigated the combined effects of uniaxial cyclic strain and TGF-{beta}1 stimulation on MSCs. By using a proteomic analysis, we found differential regulation of several proteins and genes, such as the up-regulation of TGF-{beta}1-induced protein ig-h3 (BGH3) protein levels by TGF-{beta}1 and up-regulation of calponin 3 protein level by cyclic strain. At the gene expression level, BGH3 was induced by TGF-{beta}1, but calponin 3 was not significantly ...

2009-10-12

395

Novel snake venom ligand dendroaspis natriuretic peptide is selective for natriuretic peptide receptor-A in human heart: downregulation of natriuretic peptide receptor-A in heart failure.

We labelled Lipiodol with yttrium-90 and analysed the biodistribution in rats after intrahepatic arterial injection. An RP-18 column was used to separate {sup 90}Y from strontium-90. {sup 90}Y was retained on the column, which had been pretreated with yttrium-selective extraction reagent, di(2-ethylhexyl) phosphate, while {sup 90}Sr was washed out. A hexadentate nitrogen-donor chelating ligand N,N,N`,N`-tetrakis(2-benzymidazolylmethyl)-1,2-ethanediamine (EDTB) was synthesized by condensation of 1,2-benzenediamine and ethylene diamine tetra-acetic acid (EDTA). Lipiodol was covalently conjugated with EDTB. The final product was obtained by eluting the retained {sup 90}Y from the RP-18 column with EDTB-Lipiodol. Sixteen male rats (Sprague-Dawley) were sacrificed at 1 h, 24 h, 48 h and 72 h (four rats at each time) after injection of approximately 0.1 mCi {sup 90}Y-Lipiodol via the hepatic artery. Samples of liver, spleen, muscle, lung, kidney, bone, whole blood and ...

1995-03-01

396

MR findings in cases of suspected impacted fracture of the femoral neck

The natriuretic peptides are considered to be cardioprotective; however, their receptors have not been identified in human myocardium using radiolabeled analogs. Dendroaspis natriuretic peptide (DNP) has been recently identified as a new member of this peptide family and is thought to be less susceptible to enzymatic degradation. Therefore, we have developed the novel radiolabeled analog [125I]-DNP and used this to localize high-affinity (K(D)=0.2 nmol/L), saturable, specific binding sites in adult human heart (n=6) and coronary artery (n=8). In competition binding experiments, atrial natriuretic peptide and brain type natriuretic peptide had greater affinity for [125I]-DNP binding sites than C-type natriuretic peptide and the natriuretic peptide receptor (NPR)-C ligand, cANF. This rank order of potency suggested binding of [125I]-DNP was specific to NPR-A. Messenger RNA encoding NPR-A was identified in left ventricle and coronary artery smooth muscle, and ...

2006-06-15

397

Effects of chronic swimming training on cardiac sarcolemmal function and composition.

Purpose: To evaluate MR imaging of the hip in patients with a clinically suspected impacted fracture of the femoral neck in cases where conventional plain films show negative or equivocal findings. Material and Methods: Twenty-seven such patients were prospectively examined by MR imaging with a 1.0 T unit, within 24 hours of admittance to hospital. A coronal T1-weighted turbo spin-echo sequence (n=27), and a coronal STIR sequence (n=25) or a coronal T2-weighted turbo spin-echo fast saturation sequence (n=2) were used. The evaluations were made by 2 radiologists with experience in musculoskeletal radiology. Results: There were 6 patients with a petrochanteric fracture, 2 without and 4 with slight displacement. Five patients had an impacted fracture of the femoral neck, and 3 had a fracture of the superior pubic bone. Of 2 patients with advanced arthrosis, i had an impacted femoral neck fracture and the other a nondisplaced intertrochanteric fracture. There was 1 patient who had ...

1997-09-01

398

Cytotoxic evaluation of N-isopropylacrylamide monomers and temperature-sensitive poly(N-isopropylacrylamide) nanoparticles

Cardiac contractile function is dependent on the integrity and function of the sarcolemmal membrane. Swimming exercise training is known to increase cardiac contractile performance. The purpose of the present study was to examine whether a swimming exercise program would alter sarcolemmal enzyme activity, ion flux, and composition in rat hearts. After approximately 11 wk of exercise training, cardiac myosin and actomyosin Ca2+-adenosinetriphosphatase (ATPase) activity was significantly higher in exercised rat hearts than in sedentary control rat hearts. Glycogen content was increased in plantaris and gastrocnemius muscles from exercised animals as was succinic dehydrogenase activity in gastrocnemius muscle of exercised rats in comparison to sedentary rat preparations. Sarcolemmal vesicles were isolated from hearts of exercise-trained and control rats. Sarcolemmal Na+-K+-ATPase and K+-p-nitrophenylphosphatase activities, Na+-Ca2+ exchange, and ...

1989-04-01

399

Cysteinyl peptides of rabbit muscle pyruvate kinase labeled by the affinity label 8-((4-bromo-2,3-dioxobutyl)thio)adenosine 5 prime -triphosphate

The objective of this research project is to investigate the biocompatibility of N-isopropylacrylamide (NIPAAm) monomers and poly(N-isopropylacrylamide) (PNIPAAm) nanoparticles in vitro. PNIPAAm nanoparticles of different sizes were synthesized and characterized by transmission electron microscopy and dynamic light scattering. Cytotoxicity studies using MTS assays were conducted on fibroblasts, smooth muscle cells, and endothelial cells. In addition, the concentration of NIPAAm monomers remaining on PNIPAAm nanoparticles was determined using bromination and spectrophotometry. The cytotoxicity results did not show a significant difference in cell survival when cells were exposed to different particle sizes (100, 300, and 500 nm). Dose studies showed that all three cell types exposed to 100 nm PNIPAAm nanoparticles at concentrations less than or equal to 5 mg/mL were compatible, while cells exposed to NIPAAm monomers exhibited toxicity even at very low ...

2009-08-15

400

Abdominal adipose tissue distribution in obese children. US versus CT measurements; Valutazione della distribuzione del tessuto adiposo addominale nei bambini obesi. Confronto tra ecografia e Tomografia Computerizzata

The affinity label 8-((4-bromo-2,3-dioxobutyl)thio)adenosine 5{prime}-triphosphate (8-BDB-TA-5{prime}-TP) reacts covalently with rabbit muscle pyruvate kinase, incorporating 2 mol of reagent/mol of enzyme subunit upon complete inactivation. Protection against inactivation is provided by phosphoenolpyruvate, K{sup +}, and Mn{sup 2+} and only 1 mol of reagent/mol of subunit is incorporated. The authors have now identified the resultant modified residues. After reaction with 8-BDB-TA-5{prime}-TP at pH 7.0, modified enzyme was incubated with ({sup 3}H)NaBH{sub 4} to reduce the carbonyl groups of enzyme-bound 8-BDB-TA-5{prime}-TP and to introduce a radioactive tracer into the modified residues. Following carboxymethylation and digestion with trypsin, the radioactive peptides were separated on a phenylboronate agarose column followed by reverse-phase high-performance liquid chromatography in 0.1% trifluoroacetic acid with an acetonitrile gradient. Gas-phase sequencing ...

1990-03-13

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

401

Two-stage, close coupled catalytic liquefaction of coal. Fourteenth quarterly report, 1 January 1992--31 March 1992

Computed Tomography (CT) and, more recently, ultrasound (US), have proved excellent tools for quantifying adipose tissue distribution. Body fat distribution is an important factor in the treatment of obesity and its complications. In this work it is investigated the correlation between CT and US measurements in pediatric obesity. Forty obese children and adolescents aged 4.1-14.8 years were submitted to CT and US. Intra-abdominal, subcutaneous and total body fat were calculated (in cm{sup 2}), with the CT image analysis software. The rectus muscle-spine and rectus muscle-aorta distances, as indicative of visceral fat thickness, were measured on US images with(out) compression. The distance between skin fat and fat-rectus muscle interfaces was measured as subcutaneous fat thickness. US-CT findings have been compared with other morphometric variables-i.e., patient's (ideal) body weight and skin fold measures. A ...

1999-12-01

402

Transvesical Blockade of the Obturator Nerve to Prevent Adductor Contraction in Transurethral Bladder Surgery

This quarterly report covers activities of the Two-Stage, Close- Coupled Catalytic Liquefaction of Coal program during the period January 1,--March 31,1992, at Hydrocarbon Research, Inc. in Lawrenceville and Princeton, New Jersey. This DOE contract period is from October 1, 1988 to September 30, 1992. The overall purpose of the program is to achieve higher yields of better quality transportation and turbine fuels and to lower the capital and production costs in order to make the products from direct coal liquefaction competitive with other fossil fuel products. The quarterly report covers work on Laboratory Testing, PDU Activities and Administration.

1992-04-01

403

British Library Electronic Table of Contents (United Kingdom)

Abstract Purpose: To evaluate the efficacy of transvesical obturator nerve block (ONB) in the prevention of obturator nerve reflex and leg jerking during transurethral resection of bladder tumors (TURBT). Patients and Methods: A total of 60 patients were studied, in whom the transurethral resection of tumors on the posterolateral bladder wall were performed under spinal anesthesia (SA). The patients were randomly divided into two groups. In the first group, we performed transvesical ONB and SA together, while the second group received only SA. The patients underwent TURBT using monopolar cautery. Incidence of leg jerking was registered and compared in these two groups. We used a nerve stimulator to detect the obturator nerve next to the lateral bladder wall. The obturator nerve was identif...

2010-01-01

404

The effects of chemicals in the presence of cellophane on X-ray-induced point mutation and gene conversion in Aspergillus midulans

The Computation Directorate at Lawrence Livermore National Laboratory

The presence of washed or unwashed cellophane alone or together with a bleomycin, mitomycin C or hydrochlorothiazide, ('Esidrex') showed no appreciable effect on survival of either unirradiated or irradiated conidia. Irradiation for a period of 20min reduced the survival of conidia to 20%. The growth of irradiated conidia in the presence of bleomycin, mitomycin C or Esidrex is associated with a 2- to 3-fold increase in the frequency of gene convertants, but was not accompanied by an increase in point mutants. When conidia were grown on cellophane but otherwise treated as before the frequency of gene convertants was increased 8-fold, but induction of point mutants was negligible. This effect was the same for irradiated and unirradiated conidia. The environment created by the cellophane in contract with the medium appears to affect the action of each of the three compounds synergistically. (author).

405

Targeting mid-size customers through innovative pricing strategies: An approach to assessing customer contestability

The Computation Directorate at Lawrence Livermore National Laboratory has four major areas of work: (1) Programmatic Support -- Programs are areas which receive funding to develop solutions to problems or advance basic science in their areas (Stockpile Stewardship, Homeland Security, the Human Genome project). Computer scientists are 'matrixed' to these programs to provide computer science support. (2) Livermore Computer Center (LCC) -- Development, support and advanced planning for the large, massively parallel computers, networks and storage facilities used throughout the laboratory. (3) Research -- Computer scientists research advanced solutions for programmatic work and for external contracts and research new HPC hardware solutions. (4) Infrastructure -- Support for thousands of desktop computers and numerous LANs, labwide unclassified networks, computer security, computer-use policy.

2006-09-07

406

Substitution of neodymium in the Formula Not Shown superconductor

This paper outlines an approach to develop estimates of individual customer contestability using a combined statistical and engineering analysis. The approach is targeted for use for mid-size commercial and industrial customers who are not being considered for individual flexible pricing contracts. Contestability is defined as the potential lost revenue associated with customers leaving the utility or significantly reducing electricity purchases. Contestability is modeled from the customer`s perspective using a two-stage decision process. In the first stage, the customer decides if he will continue to purchase electricity from the utility (referred to as customer retention), and in the second stage, the customer determines the amount of electricity purchased (referred to as load retention). Measures of individual customer contestability will be key factors in developing market segments and new rate offerings in future energy markets.

1996-03-01

407

British Library Electronic Table of Contents (United Kingdom)

The Fe-based copper oxide Formula Not Shown exhibits superconductivity around 50K only when it is properly annealed in Formula Not Shown atmosphere and subsequently in Formula Not Shown atmosphere. In contract Formula Not Shown does not exhibit superconductivity even if it is annealed along the same process as Formula Not Shown . We have synthesized the polycrystalline samples of Formula Not Shown solid solution system Formula Not Shown to investigate the Nd substitution effects. DC magnetization measurements have shown that, the samples in a range of Formula Not Shown exhibit superconductivity and Formula Not Shown was reduced with increasing the Nd content. However, we could not observe the superconductivity for Formula Not Shown and 1. Rietveld refinement results revealed that due to th...

2008-01-01

408

Study on probability of failure for RPV nozzle region under severe accident conditions

Studies on the chemical composition and possible mechanisms underlying the antispasmodic and bronchodilatory activities of the essential oil of Artemisia maritima L.

Most of previous study for creep rupture of RPV lower head under severe accident condition, have been focused on global failure of RPV lower head. In contract, the local failure of the RPV nozzle region has not been studied in detail. The existence and features of nozzle failure in LAVA-ICI specimen of KAERI and LHF-4 specimen of Sandia National Lab., are observed. It is confirmed that the nozzle failure of LHF-4 specimen is due to the hoop stress in the RPV. The tensile tests in various temperatures and the creep rupture tests in various temperatures and stresses, are accomplished. The finite element analysis for LAVA-ICI experiment was confirmed, and the stress and deformation analysis results are used in LAVA-ICI experiment. 17 refs., 34 figs., 3 tabs. (Author)

2001-04-01

409

British Library Electronic Table of Contents (United Kingdom)

This study describes the chemical composition of the essential oil of Artemisia maritima (Am.Oil) and the pharmacological basis for its medicinal use in gut and airways disorders. Twenty five compounds, composing 93.7% of the oil, were identified; among these, chrysanthenyl propionate and elixene were identified for the first time from any Artemisia species. The Am.Oil (0.3?1.0 mg/mL) suppressed spontaneous and high K+ (80 mM)-induced contractions in isolated rabbit jejunum, suggestive of an antispasmodic effect mediated possibly through calcium channel blockade. The calcium channel blockade activity was confirmed when pre-treatment of the tissue with Am.Oil (0.01?0.03 mg/mL) shifted the Ca++ concentration-response curves to the right, similar to verapamil and papaverine. In isolated trach...

2011-01-01

410

Report on {open_quotes}inspection of human subject research in intelligence and intelligence-related projects{close_quotes}

Radiation: how safe is safe?

Executive Order 12333, {open_quotes}United States Intelligence Activities,{close_quotes} (1) designates the Department`s intelligence element as a member of the Intelligence Community, and (2) states that no agency within the Intelligence community shall sponsor, contract for or conduct research on human subjects except in accordance with guidelines issued by the Department of Health and Human Services. The Federal policy for the Protection of Human Subjects, which was based on Department of Health and Human Services regulations, was promulgated in Title 10 Code of Federal Regulations Part 745 by the Department of Energy. The purpose of this inspection was to review the internal control procedures used by the Office of Nonproliferation and National Security to manage selected intelligence and intelligence-related projects that involve human subject research.

1996-01-16

411

Radiation: how safe is safe

Recent research findings of epidemiologist Alice Stewart suggest that nuclear workers may be at risk of contracting cancer even though their measured occupational doses fall within current safety standards. It is argued that these standards are inappropriate as they are based on extrapolations of studies on survivors of the Hiroshima and Nagasaki explosions. These individuals received single doses of radiation, whereas today's nuclear industry personnel are exposed to low-level ionizing radiation over the length of their working lives. Stewart's team linked low dose occupational exposure to ionizing radiation with an increased risk of cancer in respiratory, digestive and blood-forming tissues. The nuclear industry and United States government agencies hotly contest these assertion with their potentially damaging political and economic consequences. (UK).

1993-05-01

412

Plane-wave-basis pseudopotential calculations of the surface relaxations of Ti(0001) and Zr(0001)

Recent research findings of epidemiologist Alice Stewart suggest that nuclear workers may be at risk of contracting cancer even though their measured occupational doses fall within current safety standards. It is argued that these standards are inappropriate as they are based on extrapolations of studies on survivors of the Hiroshima and Nagasaki explosions. These individuals received single doses of radiation, whereas today's nuclear industry personnel are exposed to low-level ionizing radiation over the length of their working lives. Stewart's team linked low dose occupational exposure to ionizing radiation with an increased risk of cancer in respiratory, digestive and blood-forming tissues. The nuclear industry and United States government agencies hotly contest these assertion with their potentially damaging political and economic consequences. (UK).

1993-05-15

413

Photovoltaics: Contract lists, fiscal year 1992

The relaxations of the Ti(0001) and Zr(0001) surfaces are studied using the plane-wave-basis pseudopotential method within the local-density approximation. We find that the first interlayer spacings of Ti(0001) and Zr(0001) are contracted with respect to the bulk spacings by 6.8% and 6.1%, respectively. Such large relaxations for the close-packed surfaces of Ti and Zr are in good agreement with recent linear-augmented-plane-wave calculations. In addition, we predict a weak vibrational effect on the surface relaxation of Zr(0001) by considering the free energy in the quasiharmonic approximation. This result can be attributed to a very strong bonding between the first- and second-layer Zr atoms as a consequence of the bond-order endash bond-length correlation. copyright 1997 The American Physical Society.

414

PHOTON-HADRON INTERACTIONS AT RHIC AND LHC ENERGIES.

US DOE`s Photovoltaics Program has helped photovoltaic technologies evolve from materials and concepts in laboratories to competitive products rolling off automated assembly lines. The program is working to expand industrial capacity while continuing basic and applied technology R and D. This document is a tabulation of photovoltaics R and D that were begun, continued, or completed during this period. National laboratories or industrial, academic, and nonprofit research institutions perform the RR and D activities. The document is organized first by directing organization, then by project title and individual task. Each listing provides the name of contractor, period of performance, funding, objectives, accoplishments, and FY 1993 milestones. An index of contractors is included. (DLC)

1993-03-01

415

Nuclear thermal-hydraulics education: the Yankee Atomic/University of Lowell experience

Heavy Ion Collisions at RHIC and LHC energies are potentially an interesting laboratory for the study of QED. In these collisions, a Heavy Ion in one beam sees a highly Lorentz contracted electric field due to an oncoming beam particle. The Electric field reaches a maximum value of E {approx_equal} {gamma}{sub eff} {center_dot} Z {center_dot} e/b{sup 2}, where the apparent Lorentz factor, {gamma}{sub eff} = 2 {center_dot} {gamma}{sub beam}{sup 2} - 1. The collision may be viewed in terms of a flux of photons colliding with a stationary ion target using the equivalent photon approximation, originally introduced by Fermi in 1924. We show that the cross section for Inelastic Electromagnetic Interactions of Heavy Ions are both calculable and have been measured in the first RHIC running period.

2002-03-01

416

Mechanical stability of the diamond-like carbon film on nitinol vascular stents under cyclic loading

This paper summarizes the long and meaningful relationship between the University of Lowell (UL) and Yankee Atomic Electric Company (YAEC) in the area of nuclear thermal hydraulics. The UL has actively interacted with YAEC for many years. Many UL graduates from the nuclear program as well as health physics and other disciplines are employed by YAEC. Furthermore, many students have worked for YAEC on a part-time basis through summer employment or the coop program. Several graduate students have completed their thesis work under the joint direction of UL and YAEC personnel, and some faculty members have had consulting and research contracts with the company. At the same time, YAEC employees have taken advantage of the graduate program offered by UL and have earned advanced degrees. Some YAEC personnel have taught courses at UL and have served on the industrial advisory committees.

1986-11-16

417

Managing design and construction of the Central North Sea FPSO

The mechanical stability of diamond-like carbon (DLC) films coated on nitinol vascular stents was investigated under cyclic loading condition by employing a stent crimping system. DLC films were coated on the vascular stent of a three dimensional structure by using a hybrid ion beam system with rotating jig. The cracking or delamination of the DLC coating occurred dominantly near the hinge connecting the V-shaped segments of the stent where the maximum strain was induced by a cyclic loading of contraction and extension. However the failures were significantly suppressed as the amorphous Si (a-Si) buffer layer thickness increased. Interfacial adhesion strength was estimated from the spalled crack size in the DLC coating for various values of the a-Si buffer layer thickness.

2008-12-01

418

MPS [More Power Submarine] cables could be MIND [Mass Impregnated Non-Draining Cable] blowing for 1200 MW links

Shell UK Exploration and Production, operating in the North Sea on behalf of Shell UK and Esso UK is presented developing the Teal and Guillemot fields in the Central North Sea (CNS). As part of this development it contracted with Single Buoy Moorings Inc., (SBM) for the design, supply and installation of a newbuilt floating Production Storage and Offloading (FPSO) vessel. The work is executed in close cooperation between Shell Expro (Client) and SBM (Contractor) and its main sub contractors. The system is due to be installed during the third quarter of 1996. After a short description of the field development and the FPSO vessel this paper outlines the contractual arrangements and the organization set-up to perform the work. A summary of the lessons learned (by SBM) is given. The opinions expressed in this paper are entirely that of the author and may not necessarily reflect the opinion of other parties involved in the CNS FPU project.

1996-12-31

419

Logistics management of Paraho residual shale oil. Final report

ABB High Voltage Cables AB started the MPS (More Power Submarine cables) project in 1993 with a view to exploring new technology opportunities. The goal is to design and type test a submarine HVDC cable for a capacity of 1200 MW at 600 kV. On the day before ABB announced its success in winning the contract for the world`s largest ever submarine HVDC link project for the gigantic Bakun project in Malaysia, ABB Power Systems described progress to date at a symposium in Karlskrona. The proceedings included a test demonstration on an extruded cable which eventually broke down at a stress of over 935 kV -not in the insulation itself but in the end terminations. The electric field was in excess of 200 kV/mm which is higher than ever before reported. (UK)

1996-07-01

420

Local heat transfer augmentation in channels with two opposite ribbed surfaces

In January of 1977 the Paraho Development Company under contract with the United States Navy began a semi-works project to produce and refine up to 100,000 barrels of crude shale oil. Although the primary objective of the project was to produce specification turbine and diesel transportation fuels for field testing by the military field testing, the full-scale refinery run also produced a substantial quantity of hydrotreated shale oil residue. In 1978 the Electric Power Research Institute, recognizing the utilization potential of this material as a fuel for utility combustion turbines, obtained 4300 barrels of the residual shale oil product for future field testing. This report describes the processes involved in producing, handling, and storing the residual shale oil test material. The report also includes detailed chemical and physical analyses of the test material. In addition, guidelines which can be applied to future work with this type of synthetic fuel are ...

1980-03-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

421

Linear family of Lie brackets on the space of matrices $Mat(n\\times m,\\K)$ and Ado's Theorem

The local heat transfer coefficient distribution of a square channel with two opposite ribbed walls was determined. The square channel was connected to a sudden contraction entrance in order to simulate the inlet condition of the turbine blade cooling passages. The test channel was heated by thin stainless steel foils with a thickness of 0.000025 m, and instrumented with 180 thermocouples. The brass ribs of a square cross-section were glued periodically, in line, onto the top and bottom walls of the foil-heated channel in patterns to achieve the desired spacing and angle-of-attack. The local heat transfer coefficients on the smooth side and the ribbed side walls, at the channel entrance and the downstream regions, were measured for eight rib configurations and three Reynolds numbers (Re = 10,000, 30,000, and 60,000).

1986-01-01

422

Laser-assisted solar cell metallization processing. Quarterly report No. 7, July 1-September 30, 1985

In this paper we classify a linear family of Lie brackets on the space of rectangular matrices $Mat(n\\times m,\\K)$ and we give an analogue of the Ado's Theorem. We give also a similar classification on the algebra of the square matrices $Mat(n, \\K)$ and as a consequence, we prove that we can't built a faithful representation of the $(2n+1)$-dimensional Heisenberg Lie algebra $\\mathfrak{H}_n$ in a vector space $V$ with $\\dim V\\leq n+1$. Finally, we prove that in the case of the algebra of square matrices $Mat(n,\\K)$, the corresponding Lie algebras structures are a contraction of the canonical Lie algebra $\\mathfrak{gl}(n,\\K)$.

2008-01-01

423

Laser-assisted solar cell metallization processing. Annual report, December 13, 1984-September 30, 1985

The major goal of this contract is to define fine grid lines using laser-assisted metallization and to demonstrate the fabrication of high-efficiency cells using this process. During this period a solar cell run was completed using low-resistivity float-zone silicon. Grid lines were written by spinning silver neodecanoate solution after the Ti-Pd evaporation. This run produced cell efficiencies as high as 11.2% prior to antireflection coating and 16.6% after the AR coating. Open-circuit voltage was approx.604 mV and short-circuit current density was approx.35 mA/cmS.

1985-10-15

424

Laser Photobiomodulation of Wound Healing in Diabetic and Non-Diabetic Mice: Effects in Splinted and Unsplinted Wounds

In this contract, Laser-assisted processing techniques for producing high-quality solar cell metallization patterns are being investigated, developed, and characterized. The tasks comprising these investigations are outlined. Four new batches of solar cells were processed, in addition to several test runs on wafers, using the laser decomposition of spun-on silver neodecanoate to metallize cells. Decomposition of silver neodecanoate was carried out at different laser powers on different cells on a given wafer to determine whether this would have any effect on cell performance. A one watt laser power gave an electroplated linewidth of 50 ..mu..m, while at 8 watts the line width was 90 ..mu..m.

1986-01-06

425

British Library Electronic Table of Contents (United Kingdom)

Abstract Objective: The aim of this investigation was to compare the healing of laser-irradiated and non-irradiated wounds covered by an occlusive dressing in mice. Background data: Many previous studies of the effects of laser irradiation of experimental wounds in mice and rats did not cover the wounds so that healing occurred mainly by contraction. Healing of covered wounds is slower and mimics more closely wound healing in humans. Materials and Methods: Forty-seven diabetic and twenty non-diabetic mice were used. A single wound (5?mm diameter) was created on the left flank of each animal and covered by Tegaderm HP dressing (Day 1). Wounds were irradiated (660?nm) for 20?s using a lower power (18?mW) or higher power (80?mW) laser starting immediately post-wounding for seven consecutive d...

2010-01-01

426

Japanese will join West Germany in funding coal-liquefaction project

International heliophysical year and basic space science in West Asia

The funding for a coal-liquefaction demonstration plant near Morgantown, W.Va., appears more certain since Japan has committed $175 million toward the project. West Germany has already signed a memorandum of understanding to contribute 25% of the expected $700 million cost. West Virginia Governor J. Rockefeller has said that he feels sure the Carter Administration will approve the project since half the money is assured. The solvent-refined-coal (SRC) demonstration program began in July 1978 with the award of two separate multiphased contracts for development of a solid process, SRC-I, and a liquid process, SRC-II. The US Department of Energy is expected to choose one of the projects for detailed design and construction by the end of fiscal 1979.

1979-05-16

427

Grain size effects on the tensile properties and deformation mechanisms of a magnesium alloy, AZ31B, sheet

This paper summarizes the IHY and BSS activities in West Asia and their importance in many Arab countries, such as Algeria, Egypt, Iraq, Jordan, Kuwait, Qatar, Saudi Arabia, UAE, etc. BSS future plans for some of these countries are as follows: It is proposed by the astronomers from the Arabian Gulf Region to build the Gulf Observatory on top of Jabal Shams (2980 msl) which will have a 2-3 m optical telescope. Libya signed a contract with a French company for building an observatory which will have a 2-m optical robotic telescope. It is also proposed to rebuild the Iraqi National Astronomical Observatory (INAO) which was destroyed during the two wars. It is planned to build a 5-6 m optical telescope and a small solar telescope on the top of Korek mountain, which has excellent observing conditions.

2007-12-01

428

From Bargmann's superselection rule to quantum Newtonian spacetime

The grain size dependence of the tensile properties and the deformation mechanisms responsible for those properties are examined for Mg alloy, AZ31B, sheet. Specifically, the Hall-Petch effect and strain anisotropy (r-value) are characterized experimentally, and interpreted using polycrystal plasticity modeling. {1 0 . 2} extension twins, {1 0 . 1} contraction twins, and so-called 'double-twins' are observed via microscopy and diffraction-based techniques, and the amount of twinning is found to increase with increasing grain size. For the sheet texture and tensile loading condition examined, {1 0 . 2} extension twinning is not expected, yet the polycrystal plasticity model predicts the observed behavior, including this 'anomalous' tensile twinning. The analysis shows that the Hall-Petch strength dependence, of the polycrystal as a whole, is primarily determined by the grain size dependence of the strength of the prismatic slip systems.

2008-07-15

429

Fatigue and creep-fatigue testing of steam filled tubular Alloy 800 specimens

Bargmann's superselection rule, which forbids the existence of superpositions of states with different mass and, therefore, implies the impossibility of describing unstable particles in non-relativistic quantum mechanics, arises as a consequence of demanding Galilean covariance of Schr\\"odinger's equation. However, the usual Galilean transformations inadequately describe the symmetries of non-relativistic quantum mechanics since they fail to take into account relativistic time contraction effects which can produce non-relativistic phases in the wavefunction. In this paper we describe the incompatibility between Bargmann's rule and Lorentz transformations in the low-velocities limit, we analyze its classical origin and we show that the Extended Galilei group characterizes better the symmetries of the theory. Furthermore, we claim that a proper description of non-relativistic quantum mechanics requires a modification of the notion of spacetime in the corresponding ...

2011-01-01

430

Evaluation of pressor and visceromotor reflex responses to bladder distension in urethane anesthetized rats

A test program was conducted under contract to Sandia National Laboratories to investigate water/steam effects on elevated temperature low cycle fatigue and creep-fatigue of Alloy 800. This report presents interpretation and analysis of the test results. Tubular specimens with water sealed inside were cycled to failure under strain control. Tests were conducted to 616K (650/sup 0/F) and 922K (1200/sup 0/F); some at 922K included tensile or compressive hold periods to simulate creep-fatigue conditions. The tubular specimens showed significantly lower lives than solid bar specimens cycled at equivalent strain ranges. Rough internal surfaces contributed to early crack initiation with these specimens. Inclusion of hold periods caused further large reductions in cycles to failure.

1982-05-01

431

British Library Electronic Table of Contents (United Kingdom)

Aims We tested cardiovascular and visceromotor reflex (VMR) responses to urinary bladder distension (UBD) in urethane anesthetized rats to see if it can replicate the response pattern and the inhibition of bladder nociceptive transmission by analgesics seen in isoflurane anesthetized animals. Methods Female Sprague-Dawley rats under 3% isoflurane anesthesia were acutely instrumented with jugular venous, carotid arterial, and bladder cannulas for drug administration, blood pressure (BP) measurement, and bladder distension, respectively. Needle electrodes were placed directly into the abdominal musculature to measure myoelectrical activity subsequent to phasic UBD (30 sec in 3 min intervals). A cardiovascular response (pressor) and a VMR response (a contraction of abdominal and hind limb mus...

2009-01-01

432

Erosive radially-slotted discharge in sheet current mode

Energy Engineering Analysis Program, Limited Energy Study, Fort Hunter-Liggett, California. Volume I

New non-stationary non-contracted form of the erosive radially-slotted discharge as a thin round sheet with the current of the azimuth direction have been discovered, its existence beings stipulated by a radial transport-wave fluxes. Characteristic features of this discharge is self-confinement of the discharge current magnitude, corresponding decrease of the current pulse duration and occurrence of an energy and substance ejection with rather unusual properties. Measurements of kinetics of the discharge current, the plasma radiation intensity and an electrical probe signal, as well as the transmission electron microscope investigations of characteristic aerodisperse aggregates arising the erosive phase, have been carried out. The probe signal duration was about 10 times greater than that of the current; its kinetics was complicated suggesting existence in the slot of two components with fundamentally different properties and states of the substance.

2001-01-01

433

Effects of chemicals in the presence of cellophane on X-ray-induced point mutation and gene conversion in Aspergillus midulans

This report summarizes all work of the Limited Energy Study, Energy Engineering Analysis Program (EEAP), Fort Hunter Liggett, California, authorized under Contract Number DACA05-92-C-0155 with the U.S. Army Corps of Engineers, Sacramento District, California. The purpose of this study is to develop projects and actions that will reduce facilities energy consumption and operating costs at Fort Hunter Liggett. Implementation of these projects will contribute to achieving the goal of the Army Facilities Energy Plan of a reduction in energy consumption per square foot of building floor area of 20 percent by FY2000 from FY1985 baseline levels.

1993-07-01

434

Effect of the induced magnetic field on peristaltic flow of a couple stress fluid

The presence of washed or unwashed cellophane alone or together with a bleomycin, mitomycin C or hydrochlorothiazide, ('Esidrex') showed no appreciable effect on survival of either unirradiated or irradiated conidia. Irradiation for a period of 20min reduced the survival of conidia to 20%. The growth of irradiated conidia in the presence of bleomycin, mitomycin C or Esidrex is associated with a 2- to 3-fold increase in the frequency of gene convertants, but was not accompanied by an increase in point mutants. When conidia were grown on cellophane but otherwise treated as before the frequency of gene convertants was increased 8-fold, but induction of point mutants was negligible. This effect was the same for irradiated and unirradiated conidia. The environment created by the cellophane in contract with the medium appears to affect the action of each of the three compounds synergistically.

1984-08-01

435

DOE steps up research on synthetic fuels

We have analyzed the MHD flow of a conducting couple stress fluid in a slit channel with rhythmically contracting walls. In this analysis we are taking into account the induced magnetic field. Analytical expressions for the stream function, the magnetic force function, the axial pressure gradient, the axial induced magnetic field and the distribution of the current density across the channel are obtained using long wavelength approximation. The results for the pressure rise, the frictional force per wave length, the axial induced magnetic field and distribution of the current density across the channel have been computed numerically and the results were studied for various values of the physical parameters of interest, such as the couple stress parameter ?, the Hartmann number M, the magnetic Reynolds number R and the time averaged mean flow rate ?. Contour plots for the stream and magnetic force functions are obtained and the trapping phenomena for the flow field ...

2008-06-01

436

DOE Plutonium Disposition Study: Pu consumption in ALWRs. Volume 1, Final report

The U.S. Department of Energy has awarded contracts to Pittsburg and Midway Coal Mining Co. and to Southern Company to design plants for the conversion of 6000 tons/day of coal by two variations of the Solvent Refined Coal (SRC) process The Federal research effort is focused on direct liquefaction by hydrogen addition, including the SRC process; the Exxon Donor Solvent (EDS) process, for which Exxon Corp. plans to scale up technology to a 250 ton/day pilot plant; and Hydrocarbon Research Inc.'s H-Coal process, for which a 2000 bbl/day pilot plant is under construction. The roles of other companies in the coal liquefaction research are also discussed.

1978-09-01

437

Creating reliable pharmaceutical distribution networks and supply chains in African countries: Implications for access to medicines

The Department of Energy (DOE) has contracted with Asea Brown Boveri-Combustion Engineering (ABB-CE) to provide information on the capability of ABB-CE`s System 80 + Advanced Light Water Reactor (ALWR) to transform, through reactor burnup, 100 metric tonnes (MT) of weapons grade plutonium (Pu) into a form which is not readily useable in weapons. This information is being developed as part of DOE`s Plutonium Disposition Study, initiated by DOE in response to Congressional action. This document, Volume 1, presents a technical description of the various elements of the System 80 + Standard Plant Design upon which the Plutonium Disposition Study was based. The System 80 + Standard Design is fully developed and directly suited to meeting the mission objectives for plutonium disposal. The bass U0{sub 2} plant design is discussed here.

1993-05-15

438

British Library Electronic Table of Contents (United Kingdom)

The presence of inefficient distribution networks and supply chains of medicines creates problems in that even if African countries can secure steep, sustainable cost-containing procurements, access to needed medicines may still be impaired. The expected health benefits from affordable pricing or subsidies on prices of medicines may not be realized. This article evaluates drug supply chains in African countries and advocates for consolidated private wholesale markets and multiplicity of retail pharmacies. Public supply chains should be shortened and supported by contracting out with private distributors, including wholesalers and retail pharmacies. Additionally, drug regulatory authorities should be allowed to charge registration fees that are proportionate to the costs of technical regula...

2009-01-01

439

Crawling beneath the free surface: Water snail locomotion

Cosmic time dilation: The clock paradox revisited

Land snails move via adhesive locomotion. Through muscular contraction and expansion of their foot, they transmit waves of shear stress through a thin layer of mucus onto a solid substrate. Since a free surface cannot support shear stress, adhesive locomotion is not a viable propulsion mechanism for water snails that travel inverted beneath the free surface. Nevertheless, the motion of the freshwater snail, Sorbeoconcha physidae, is reminiscent of that of its terrestrial counterparts, being generated by the undulation of the snail foot that is separated from the free surface by a thin layer of mucus. Here, a lubrication model is used to describe the mucus flow in the limit of small amplitude interfacial deformations. By assuming the shape of the snail foot to be a traveling sine wave and the mucus to be Newtonian, an evolution equation for the interface shape is obtained and the resulting propulsive force on the snail is calculated. This propulsive force is found ...

2008-01-01

440

Cooperative research in coal liquefaction infratechnology and generic technology development: Final report, January 1, 1987 to April 30, 1988

The relativistic time dilation is reviewed in a cosmological context. We show that a clock or twin paradox does not arise if cosmic time is properly taken into account. The receding galaxy background provides a unique frame of reference, and the proper times of geodesic as well as accelerated observers can be linked to the universal cosmic time parameter. This suggests to compare the proper time differentials of the respective observers by determining their state of motion in the galaxy grid. In this way, each observer can figure out whether his proper time is dilated or contracted relative to any other. In particular one can come to unambiguous conclusions on the aging of uniformly moving observers, without reference to asymmetries in measurement procedures or accelerations they may have undergone.

2004-05-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

441

Construction Progress of the Cooling and Ventilation in the LHC Project

The Consortium for Fossil Fuel Liquefaction Science (CFFLS) is a research consortium that includes five universities and a state energy laboratory. The membership is comprised of Auburn University, the University of Kentucky, the University of Pittsburgh, the University of Utah, West Virginia University, and the Kentucky Energy Cabinet Laboratory. The Consortium was formed in 1984 in response to the concern of the faculty and scientists at these institutions over the decline of coal liquefaction research in the United States, particularly long-range, basic research. Significant progress towards these goals was made in the current contract period. Major research accomplishments are presented on coal desulfurization, coprocessing, pyrolysis, enhanced reactivity, characterization, resource evaluation and database development. 108 refs., 90 figs., 38 tabs.

1988-05-10

442

Computational modeling of dynamic-failure mechanisms in armor/anti-armor materials. Final report, 1 Oct 88-30 Sep 91

The Cooling and Ventilation Group has started the LHC construction work in September 1999 and will get into full activity when LEP will be stopped and dismantled: in total 12 major contracts for an amount of about 120 MCHF will be established to build the needed installations for the LHC. The author will report on the current works that are in progress on the different LEP Points distinguishing between the Ventilation and the Water Cooling installations. The Ventilation work, completed in the new surface buildings in Points 18, is currently held in Points 4 and 5. Point 1 will follow in the near future. The work for the Cooling plants comprehend the pumping stations, the cooling towers and the chilled water production stations in Points 1 and 5, the buried pipes in Points 1 and 4. For all of these activities, an updated report of the progress of the work, of the planning and of the expenses is given. Finally, a short overview of the future activities is presented.

2001-01-01

443

Class 1E digital systems studies

The purpose of this project was to develop improved dynamic failure models for brittle materials (primarily ceramics). The approach to developing these failure models was to establish a database (ACERAM) in which fundamental material properties and processing information could be directly correlated with ballistic performance data. Under this contract, a comprehensive literature search was conducted, many contacts were established in the armor/anti-armor research and development community, and database development was undertaken. A more limited project was also undertaken to assess and compare the effects of material properties and penetration mechanisms on the ballistic performance of depleted uranium and tungsten alloy penetrators.

1991-02-01

444

Bianchi type IX brane-world cosmologies

This document is furnished as part of the effort to develop NRC Class 1E Digital Computer Systems Guidelines which is Task 8 of USAF Rome Laboratories Contract F30602-89-D-0100. The report addresses four major topics, namely, computer programming languages, software design and development, software testing and fault tolerance and fault avoidance. The topics are intended as stepping stones leading to a Draft Regulatory Guide document. As part of this task a small scale survey of software fault avoidance and fault tolerance practices was conducted among vendors of nuclear safety related systems and among agencies that develop software for other applications demanding very high reliability. The findings of the present report are in part based on the survey and in part on review of software literature relating to nuclear and other critical installations, as well as on the authors' experience in these areas.

445

BR-100 spent fuel shipping cask development

We investigate the asymptotic properties of the Bianchi type IX cosmological model in the brane-world scenario. The matter content is assumed to be a combination of a perfect fluid and a minimimally coupled scalar field that is restricted to the brane. A detailed qualitative analysis of the Bianchi type IX brane-world containing a scalar field having an exponential potential is undertaken. It is found that the brane-Robertson-Walker solution is a local source for the expanding Bianchi type IX models, and if k"2<2 the ever-expanding Bianchi IX models asymptote to the power-law inflationary solution. The only other local sink is the contracting brane-Robertson Walker solution. An analysis of the Bianchi type IX models with a scalar field with a general potential is discussed, and it is shown that in the case of expanding models, for physical scalar field potentials close to the initial singularity, the scalar field is effectively massless, and the solution is ...

2003-07-15

446

Asymmetric Totally-corrective Boosting for Real-time Object Detection

Continued public acceptance of commercial nuclear power is contingent to a large degree on the US Department of Energy (DOE) establishing an integrated waste management system for spent nuclear fuel. As part of the from-reactor transportation segment of this system, the B W Fuel Company (BWFC) is under contract to the DOE to develop a spent-fuel cask that is compatible with both rail and barge modes of transportation. Innovative design approaches were the keys to achieving a cask design that maximizes payload capacity and cask performance. The result is the BR-100, a 100-ton rail/barge cask with a capacity of 21 PWR or 52 BWR ten-year cooled, intact fuel assemblies. 3 figs.

1990-01-01

447

Assess Current and Potential Salmonid Production in Rattlesnake Creek Associated with Restoration Efforts; Yakama Indian Nation, Annual Report 2002-2003.

Real-time object detection is one of the core problems in computer vision. The cascade boosting framework proposed by Viola and Jones has become the standard for this problem. In this framework, the learning goal for each node is asymmetric, which is required to achieve a high detection rate and a moderate false positive rate. We develop new boosting algorithms to address this asymmetric learning problem. We show that our methods explicitly optimize asymmetric loss objectives in a totally corrective fashion. The methods are totally corrective in the sense that the coefficients of all selected weak classifiers are updated at each iteration. In contract, conventional boosting like AdaBoost is stage-wise in that only the current weak classifier's coefficient is updated. At the heart of the totally corrective boosting is the column generation technique. Experiments on face detection show that our methods outperform the state-of-the-art asymmetric boosting methods.

2010-01-01

448

Advances in operations research in the oil and gas industry

This document represents the FY2002 BPA contract Statement of Work for the Yakama Nation (YN) portion of the project entitled 'Assessment of current and potential salmonid production in Rattlesnake Creek associated with restoration efforts'. The purpose of the project is to complete detailed surveys of water quality, fish populations, habitat conditions and riparian health in the Rattlesnake Creek sub-basin of the White Salmon River in south central Washington. Results of the surveys will be used to establish Rattlesnake Creek sub-basin baseline environmental factors prior to anticipated removal of Condit Dam in 2006 and enable cost-effective formulation of future watershed restoration strategies.

2003-05-01

449

ASPEN simulation of environmental control processes: Final report

Various theories and examples of modelling, forecasting and optimization designing in the different parts of the petroleum and gas industries are presented, stochastic programming for long term planning in the refining industry, stochastic model for gasoline blending, feedstock optimization, location and sizing for offshore platforms, hydrocarbon exploration simulation rapid method, valuation of oil field development leases, economic models for petroleum allocation, models for oil supply market, trade embargo game theory, stochastic programming of gas contract portfolio management, scheduling transportation of oil and gas, strategic planning in an oil pipeline company, simulation of offshore oil terminal systems, hierarchical selection of oil and gas distribution systems.

1991-06-13

450

A patient specific electro-mechanical model of the heart

The United States Department of Energy (DOE) at the Morgantown Energy Technology Center (METC) contracted with P.S. Lowell and Co. Inc. (Lowell and Co.) and Jay S. Dweck, Consultant, Inc., (JSD) to enhance the capability of ASPEN in simulating coal gasification and oil shale processing plants. Of particular concern was the capability to predict the distribution of environmentally significant components among the various aqueous and organic liquids and gas streams within or leaving the process. The project was divided into major task areas. The first was to develop and implement the calculational routines necessary for predicting aqueous electrolyte chemical reactions. Part of this effort also was to select a species list and collect and/or regress data for the necessary parameters. The second task was to develop and implement a multi-phase flash capability (including precipitated solids) and unit operations models for a venturi and a solid/liquid separator. 19 ...

1988-04-01

451

British Library Electronic Table of Contents (United Kingdom)

This paper presents a patient specific deformable heart model that involves the known electrical and mechanical properties of the cardiac cells and tissue. The whole heart model comprises ten Tusscher's ventricular and Nygren's atrial cell models, the anatomical and electrophysiological model descriptions of the atria (introduced by Harrild et al.) and ventricle (given by Winslow et al.), and the mechanical model of the periodical cardiac contraction and resting phenomena proposed by Moireau et al. During the propagation of the depolarization wave, the kinetic, compositional and rotational anisotropy is handled by the tissue, organ and torso model. The applied patient specific parameters were determined by an evolutionary computation method. An intensive parameter reduction was performed u...

2011-01-01

452

2D Thermal Hydraulic Analysis and Benchmark in Support of HFIR LEU Conversion using COMSOL

Transmutations of nuclear waste. Progress report RAS programme 1995: Recycling and transmutation of actinides and fission products

The research documented herein was funded by a research contract between the Research Reactors Division (RRD) of Oak Ridge National Laboratory (ORNL) and the University of Tennessee, Knoxville (UTK) Mechanical, Aerospace and Biomedical Engineering Department (MABE). The research was governed by a statement of work (SOW) which clearly defines nine specific tasks. This report is outlined to follow and document the results of each of these nine specific tasks. The primary goal of this phase of the research is to demonstrate, through verification and validation methods, that COMSOL is a viable simulation tool for thermal-hydraulic modeling of the High Flux Isotope Reactor (HFIR) core. A secondary goal of this two-dimensional phase of the research is to establish methodology and data base libraries that are also needed in the full three-dimensional COMSOL simulation to follow. COMSOL version 3.5a was used for all of the models presented throughout this report.

2010-09-01

453

Review of the WIPP draft application to show compliance with EPA transuranic waste disposal standards

This report describes the progress of the Dutch RAS programme on `Recycling and Transmutation of Actinides and Fission Products` over the year 1995, which is the second year of the 4-year programme 1994-1997. An extensive listing of reports and publications from 1991 to 1995 is given. Highlights in 1995 were: -The completion of the European Strategy Study on Nuclear Waste Transmutation as a result of which the understanding of transmutation of plutonium, minor actinides and long-lived fission products in thermal and fast reactors has been increased significantly. Important ECN contributions were given on Am, {sup 99}Tc and {sup 129}I transmutation options. Follow-up contracts have been obtained for the study of 100% MOX cores and accelerator-based transmutation. - Important progress in the evaluation of CANDU reactors for burning very large amounts of transuranium mixtures in inert matrices. - The first RAS irradiation experiment in the HFR, in which the ...

1996-04-01

454

Research document no. 24. The integration of european electric markets: from the national markets juxtaposition to the establishment of a regional market; Cahier de recherche no. 24. L'integration des marches electriques europeens: de la juxtaposition de marches nationaux a l'etablissement d'un marche regional

The purpose of the New Mexico Environmental Evaluation Group (EEG) is to conduct an independent technical evaluation of the Waste Isolation Pilot Plant (WIPP) Project to ensure the protection of the public health and safety and the environment. The WIPP Project, located in southeastern New Mexico, is being constructed as a repository for the disposal of transuranic (TRU) radioactive wastes generated by the national defense programs. The EEG was established in 1978 with funds provided by the U.S. Department of Energy (DOE) to the State of New Mexico. Public Law 100-456, the National Defense Authorization Act, Fiscal Year 1989, Section 1433, assigned EEG to the New Mexico Institute of Mining and Technology and continued the original contract DE-AC04-79AL10752 through DOE contract DE-AC04-89AL58309. The National Defense Authorization Act for Fiscal Year 1994, Public Law 103-160, continues the authorization. EEG performs independent technical ...

1996-03-01

455

Probabilistic endowment appraisal system based upon the formalization of geologic decisions. National Uranium Resource Evaluation. Final report: demonstration and comparative analysis of estimates and methods

After the transcription of the electricity directive in national legislations, the European electricity market appears to be a vast set of juxtaposed markets which are weakly connected at the level of their wholesale contracts compartment. Referring to the technological peculiarities of electricity as a commodity, the paper identifies the direct conditions of regional integration of the electricity markets, those which would favour cross-border trade and allow to be near the normal functioning of a regional commodity market. The infrastructure network dependence and the need of a stringent technical coordination necessitate to unify the operation of the different systems and the rules of access, or at the least to come near this unification by strong coordination. A second major condition, which is not fully debated, is the increasing connexion of short-term markets, via daily physical trade and emergence of a European financial market, which could trade various ...

2000-11-01

456

Occupational exposure to benzene: a prevention program for employees and contractors; PPEOB - Programa de Prevencao a Exposicao Ocupacional ao Benzeno para Empregados Proprios e Contratados

This report is the culmination of approximately three and one-half years of research on the design and demonstration of a mineral endowment appraisal system which has as its foundation a formalization of geological decisions within a probabilistic framework. Basically, the probabilistic decision structure of a geologist or team of geologists is captured in a system of computer programs which can be used by a geologist for the estimation of the magnitude of uranium endowment by providing information to this system about the states of earth processes and geologic conditions that pertain to that region being evaluated. Research performed under this contract had two main objectives: demonstration of the endowment appraisal system on the San Juan Basin of New Mexico; a comparison of estimates by the appraisal system with estimates made using other methodologies. The scope of this report is restricted to a demonstration of the appraisal system and the comparison of ...

1980-12-01

457

Occupational exposure prevention program to oil and gas industry; Antecipacao, reconhecimento, avaliacao e controle dos riscos ambientais em uma planta de petroleo e gas

PETROBRAS/TRANSPETRO Pipelines and Terminals has 500 regular employees and 5.064 out sourced workers in its Southeast Division. The out sourced employees work through 125 contracts involving a wide range of activities such as maintenance, operational, pipeline launching , engineering, administrative and auxiliary services. Among these workers, 200 people are subjected to benzene occupational exposure, which might be present in the products we transport in our pipelines. Benzene is recognized as a carcinogen according to ACGIH and Brazilian Ministry of Labour regulation NR- 15. Exposure to benzene in an uncontrolled way, be it chronic or sharp, may affect the worker's health such as: hematological alterations, neoplasys, neurobehavior alterations. Our program PPEOB (acronym in Portuguese for benzene occupational exposure prevention program) involved the work force and fosters health by anticipation, recognition, evaluation and control of the situations that ...

2004-07-01

458

Magnetic braking of collapsing interstellar clouds

PETROBRAS/TRANSPETRO Pipelines and Terminals have 500 regular employees and 5.064 out sourced workers in its Southeast Division. The out sourced employees work under 125 contracts involving a wide range of activities such as maintenance, pipeline operation, pipeline launching, engineering, administrative and auxiliary services. Among these workers, 1.200 peoples are subjected to occupational exposure, which may be present in the industrial process or in the products transported in our pipelines, e.g. industrial noise, sulfidric gas, toluene, xylene and benzene (recognized as a carcinogen according to ACGIH and Brazilian Ministry of Labour). Our PPRA (acronym in Portuguese for Occupational Exposure Prevention Program) involves the workforce and fosters health by anticipation, recognition, evaluation and control of the situations that may result in injuries. Further actions include the procurement of equipment for detection of these agents not only in the air but ...

2005-07-01

459

Low-activity waste envelope definitions for the TWRS Privatization Phase I Request For Proposal

The purpose of this investigation is to show that resource to anisotropic compression along a magnetic field is not a necessary condition for star formation within large collapsing interstellar gas clouds. Although such a scenario would certainly eliminate the magnetic field and angular momentum problems associated with isotropically collapsing clouds, it is believed there is sufficient observational theoretical evidence to warrant the present study of magnetically braked, isotropically collapsing gas clouds. It is not attempted to disprove the hypothesis of anisotropic compression, but to offer instead, a reasonable alternative. Angular momentum transfer from magnetically braked, cool interstellar gas clouds of 10"2, 10"3 and 10"4 times the mass of the sun is examined. Magnetic torques acting on a contracting, rotating cloud, permeated by a frozen-in magnetic field coupling the cloud to the galactic field of the surrounding interstellar medium, produce kinks in ...

460

Laser-assisted solar cell metallization processing. Quarterly report, September 13-December 12, 1983

Radioactive waste has been stored in large underground storage tanks at the Hanford Site since 1944. Approximately 212 million liters of waste containing approximately 240,000 metric tons of processed chemicals and 177 mega-curies of radionuclides are now stored in 177 tanks. These caustic wastes are in the form of liquids, slurries, saltcakes, and sludge. In 1991, the Tank Waste Remediation System (TWRS) Program was established to manage, retrieve, treat, immobilize, and dispose of these wastes in a safe, environmentally sound, and cost-effective manner. The Department of Energy (DOE) has believes that it is feasible to privatize portions of the TWRS Program. Under the privatization strategy embodied in the Request for Proposal (RFP), DOE will purchase services from a contractor-owned, contractor-operated facility under a fixed-price contract. Phase I of the TWRS privatization strategy is a proof-of-concept/commercial demonstration-scale effort. The objectives of ...

1996-11-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

461

First oil expected at White Rose in 2005

The Westinghouse Electric Corporation has undertaken to investigate, develop, and characterize laser-assisted processing techniques utilized to produce the fine line, thin metal grid structures that are required to fabricate high-efficiency solar cells. Two basic techniques for metal deposition will be investigated, as follows: (1) photochemical decomposition of liquid or gas phase organometallic compounds utilizing either a focused, CW ultraviolet laser (System 1) or a mask and ultraviolet flood illumination, such as that provided by a repetitively pulsed, defocused excimer laser (System 2), for pattern definition, and (2) thermal deposition of metals from organometallic solutions or vapors utilizing a focused, CW laser beam as a local heat source to draw the metallization pattern. The purpose of this contract is to investigate the various existing laser-assisted film deposition techniques in order to develop a new, cost-effective technology for solar cell ...

1984-01-16

462

Characterization of carbon-based electrochemical capacitor technology from Maxwell Energy Products, Inc.

Husky Oil received approval from the government to begin development of its White Rose properties located in the Jean d'Arc Basin, 350 km east of St. John's, offshore Newfoundland and Labrador. First oil is expected by the end of 2005. The South Avalon Pool was discovered in 1988 and is estimated to contain approximately 200-250 million barrels of oil. Husky Oil and Petro-Canada filed a development application with the Canada-Newfoundland Offshore Petroleum Board in January 2001. Approval of the $2.35 billion project was received in December 2001. The development plan is based on a newly-built floating production, storage and offloading (FPSO) vessel. Initial development will focus on the South Avalon Pool that has been tested in excess of 5,000 barrels per day. The pool will be developed using eight production wells, 11 water injection wells and two gas injection wells. An estimated 150 million cubic feet per day of gas will also be produced from the field. It will ...

2002-04-01

463

Annual report on heavy water reactor fuel fabrication

The electrochemical capacitor devices described in this report were deliverables from the US Department of Energy--Idaho Operations Office (DOE-ID) Contract No. DE-AC07-92ID13404 as part of the US Department of Energy`s (DOE) High Power Energy Storage Program. The Idaho national Engineering and Environmental Laboratory (INEEL) has responsibility for technical management, testing, and evaluation of high-power batteries and electrochemical capacitors under this Program. The DOE has developed various electrochemical capacitors as candidate power assist devices for the Partnership for a New Generation of Vehicles (PNGV) fast response engine requirement. This contract with Maxwell Energy Products, Inc. (Maxwell) was intended to develop a high-energy-density, high-power-density ultracapacitor that is capable of load leveling batteries in electric vehicles. The performance criteria for this device are delivery of 5 W {center_dot} h/kg of useful energy ...

1998-04-01

464

An investigation into the profitability of energy management in office buildings

The CANDU-type nuclear fuel localization project started in 1981, and mass-production system completed in 1987 through the pilot scale demonstration of fuel manufacturing. Since the completion of the mass-production system, about 24,000 fuel bundles (450 ton-U) had been delivered to Wolsung Nuclear Power Plant by the end of 1992, according to the fuel supply contracts with KEPCO. The superiority of KAERI-made nuclear fuel has been demonstrated by having achieved the highest utilization factor in the world in 1992. In 1993, as contracted, 4,824 fuel bundles well fabricated and delivered to Wolsung Nuclear Power Plant. The process improvement, quality control, safety management, safeguards of nuclear materials and various kinds of audits have also been performed in the course for fuel manufacturing. Especially in 1993, the difficulties of the reduction of participating work-force were overcome by improving the manufacturing techniques, and ...

1994-03-01

465

A summary of the California Public Utilities Commission`s two competing electric utility restructuring proposals

This thesis examines the costs and benefits of energy management in office buildings and investigates the relationships between operating costs, space lease contracts, and building value. Energy management be building owners and managers begins with monitoring and analysing building energy, use and continues by reducing energy consumption through operating procedure changes, equipment replacement and control personnel training and continued monitoring. The cost to complete energy management projects in 12 British Columbia office buildings is analyzed. The average before-tax internal rate of return for the 12 energy management programs was 22.1% on total expenditures of Canadian $1.2 million. Nine of the buildings are owned and occupied by the provincial government, and the return on investment directly benefits the public. However, in the three prvately owned and tenant-occupied buildings, the owners have a less direct method of receiving the benefits due to net ...

1988-01-01

466

The diagnostic value of MRI and gadolinium-DTPA compared with CT for the diagnosis of bladder tumours

In May 1995, the California Public Utilities Commission (CPUC) released two proposals for restructuring the state`s electric power industry. The two proposals follow more than a year of testimony and public comment after the CPUC issued the ``Blue Book`` (CPUC 1994a) on April 20, 1994, which called for retail wheeling to be phased in to all customers over 5 years. The majority proposal, supported by three of the four CPUC commissioners (one seat was vacant when the proposals were released), calls for creating a central pool, or ``poolco``; setting electric prices to reflect true costs of service, or ``real-time pricing``; and allowing parties to negotiate ``contracts for differences`` between the pool price and the contract price. The minority proposal, sponsored by Commissioner Jesse Knight, calls for retail wheeling, or ``direct access,`` and for utilities to divest or spin off their generating assets. This paper presents a summary of the ...

1995-11-01

467

Supplementation of pyruvate prevents palmitate-induced impairment of glucose uptake in C2 myotubes.

In a prospective study, 58 patients with carcinomas of the bladder were examined by CT and MRI; in 48, gadolinium-DTPA was administered intravenously. MRI provided exact staging in 89%, compared with 80% with CT. There was 13% over-staging with CT and 11% with MRI. MRI, unlike CT did not result in any under-staging. In 36 patients a quotient could be calculated from the signal intensity of the tumour and surrounding soft tissues both before and after the intravenous contrast medium and the increased quotient after contrast administration could be estimated. There was a significant increase in the tumour/muscle quotient with a mean of 72#+-#22% (minimum 43%, maximum 153%), corresponding to a marked increase of the signal form the tumour when compared with the precontrast images. This had the following advantages compared with CT: Accurate differentiation between superficial and intramural spread. MRI was better than CT at demonstrating tumours in the roof of the ...

468

Stable isotope studies on iron bio-availability in young Indian women: Effects of nutritional status, interactions and ethnicity

Elevated fatty acid levels have been thought to contribute to insulin resistance. Repression of the glucose transporter 4 (GLUT4) gene as well as impaired GLUT4 translocation may be a mediator for fatty acid-induced insulin resistance. This study was initiated to determine whether palmitate treatment repressed GLUT4 expression, whether glucose/fatty acid metabolism influenced palmitate-induced GLUT4 gene repression (PIGR), and whether attempts to prevent PIGR restored palmitate-induced impairment of glucose uptake (PIIGU) in C2 myotubes. Not only stimulators of fatty acid oxidation, such as bezafibrate, AICAR, and TOFA, but also TCA cycle substrates, such as pyruvate, leucine/glutamine, and ?-ketoisocaproate/monomethyl succinate, significantly prevented PIGR. In particular, supplementing with pyruvate through methyl pyruvate resulted in nearly complete prevention of PIIGU, whereas palmitate treatment reduced the intracellular pyruvate level. These results suggest that pyruvate ...

2011-07-23

469

Specific accumulation of arsenic compounds in green turtles (Chelonia mydas) and hawksbill turtles (Eretmochelys imbricata) from Ishigaki Island, Japan

Iron is an essential micronutrient. As an integral part of hemoglobin, it is essential for the transport of oxygen in blood to the tissues. It is an important component of cytochromes and other tissue enzymes that are critical for cellular respiration and of myoglobin that helps maintain oxygen reserve in the muscle. It is also involved in the normal functioning of the immune function, and in the synthesis of steroid hormones and bile acids. There are serious functional consequences to iron deficiency and iron deficiency anemia (IDA) in the human body. The deleterious effects include increased morbidity, preterm delivery, low birth weight, delayed cognitive development, lowered cellular immunity and reduced physical work capacity. However, iron deficiency and IDA remain the world's most common deficiency disease in the 21st century. Recent estimates of people affected with iron deficiency and IDA are 3.5 billion. Iron deficiency anemia is most prevalent and severe ...

2002-06-24

470

Soil Redox Chemistry Limitation of Selenium Concentration in Carex Species Sedges

Concentrations of total arsenic (As) and individual compounds were determined in green and hawksbill turtles from Ishigaki Island, Japan. In both species, total As concentrations were highest in muscle among the tissues. Arsenobetaine was a major compound in most tissues of both turtles. High concentrations of trimethylarsine oxide were detected in hawksbill turtles. A significant negative correlation between standard carapace length (SCL), an indicator of age, and total As levels in green turtles was found. In contrast, the levels increased with SCL of hawksbill turtles. Shifts in feeding habitats with growth may account for such a growth-dependent accumulation of As. Although concentrations of As in marine sponges, the major food of hawksbill turtles are not high compared to those in algae eaten by green turtles, As concentrations in hawksbill turtles were higher than those in green turtles, indicating that hawksbill turtles may have a specific accumulation ...

2008-05-15

471

Single-molecular analysis of the binding state of myosin V and actin

The trace element selenium (Se) is required in the production of enzymes that protect mammalian cells from oxidative damage due to the byproducts of aerobic respiration. Its deficiency in livestock results in the nutritional muscular dystrophy called white muscle disease. This especially affects juveniles in the preweaning period. Symptoms have also been reported in wild herbivores on low-Se forage, and their appearance may be episodic, suggesting temporal variations in Se uptake by plants. Here, we report variations in selenium concentrations in Carex spp. sedges used as forage by bighorn sheep (Ovis canadensis) on summer range in the Wyoming, Wind River Mountains, and correlate those variations with soil conditions that affect the bioavailability of selenium. Variations in available Se are explained based upon the known oxidation/reduction chemistry of the element. It is concluded that water-saturated, alpine soils provide conditions suitable for the reduction of ...

2007-09-01

472

SE and I content in military total diet

A class-V myosin, myosin V, one of 18 known classes of actin-based motor proteins, plays a role in transporting organelles within a cell. Unlike myosin-II, which functions as an assembly in the thick filaments of muscle, myosin V is a two-headed processive motor protein, which functions as a single molecule: myosin V performs many consecutive steps before it detaches from an actin filament accompanied by catalytic cycles of ATP (adenosine 5'-triphosphate) ase. The mechanism of such chemomechanical steps is explained by a 'Hand-over-hand model' in which two heads of myosin V alternately repeat single-headed and double-headed bindings with an actin filament. To investigate the binding state of myosin V at several key nucleotide states during ATP hydrolysis, we measured the mechanical properties of a single myosin V - actin complex by applying an external load with optical trap.

2006-03-21

473

Replication-defective vectors of reticuloendotheliosis virus transduce exogenous genes into somatic stem cells of the unincubated chicken embryo

Selenium and iodine are trace elements that play an important role in health of man and animals. Concerning supply of both elements it is important to meet nutritional needs. According to discoveries selenium is a part of an active group of glutathione peroxidase enzyme. It prevents necrotic changes in liver, muscle dystrophy and has impact on growth. Extensive studies on content of selenium in plant and animal origin products were started in the beginning of the seventies in Western Europe (Frankenberger, et al., 1998). The aim of our work was to determine selenium and iodine content in total diets of Slovene military. Slovene military nutrition is based on its own nutritional standards, which determine 200 #mu#g of iodine and 50 #mu#g of selenium in daily diet (Rep. Slovenija Ministrstvo za Obrambo, 1994). To determine if the amounts of both elements meet the standards we have analysed 20 total daily diets from four different barracks within a two month period. ...

2003-06-10

474

Radioiodinated peanut lecitin: A potential radiopharmaceutical for immunodetection of carcinoma expressing the T antigen

Replication-defective vectors derived from reticuloendotheliosis virus were used to transduce exogenous genes into early somatic stem cells of the chicken embryo. One of these vectors transduced and expressed the chicken growth hormone coding sequence. The helper cell line, C3, was used to generate stocks of vector containing about 10/sup 4/ transducing units per ml. Injection of 5- to 20-..mu..l volumes of vector directly beneath the blastoderm of unincubated chicken embryos led to infection of somatic stem cells. Infected embryos and adults contained unrearranged integrated proviral DNAs. Embryos expressed the transduced chicken growth hormone gene and contained high levels of serum growth hormone. Blood, brain, muscle, testis, and semen contained from individuals injected as embryos contained vector DNA. Replication-defective vectors of the reticuloendotheliosis virus transduced exogenous genes into chicken embryonic stem cells in vivo.

1989-06-01

475

Preclinical evidence for the benefits of penile rehabilitation therapy following nerve-sparing radical prostatectomy.

The Thomsen-Friedenreich (T) antigen, #betta#-D-Gal-(1->3)-#alpha#-D-GalNAc, is exposed in reactive form on many human adenocarcinomata, but not on corresponding benign tissues. Peanut lectin (PNA) has a strong binding affinity for the T antigen and reportedly binds preferentially to certain malignant tissues. We investigated the potential of radio-labelled PNA as a tumour localising agent in an animal model system using a mouse lymphoma (RI) shown to bind fluorescein-labelled PNA in vitro. The radio-iodinated lectin showed good tumour localisation and rapid blood clearance. Clear images of tumours were obtained, in serial scintigraphic imaging, by 24 and 48 h. No blood background subtraction was necessary. Biodistribution studies revealed tumour to blood ratios in mice were 6:1 (at 24 h) and 17:1 (at 48 h), and tumour to muscle ratios were 34:1 (at 24 h) and 40:1 (at 48 h). Rapid in vivo breakdown of _1_2_5I-PNA led to some localisation of free iodide in the ...

1983-01-01

476

Pre-operative MRI of anorectal anomalies in the newborn period

Erectile dysfunction following radical prostatectomy remains a frequent problem despite the development of nerve-sparing techniques. This erectile dysfunction is believed to be neurogenic, enhanced by hypoxia-induced structural changes which result in additional veno-occlusive dysfunction. Recently, daily use of intracavernous vasoactive substances and oral use of PDE5-inhibitors have been clinically studied for treatment of postprostatectomy erectile dysfunction. Since these studies showed benefits of "penile rehabilitation therapy," these effects have been studied in a preclinical setting. We reviewed experimental literature on erectile tissue preserving and neuroregenerative treatment strategies, and found that preservation of the erectile tissue by the use of intracavernous nitric oxide donors or vasoactive substances, oral PDE5-inhibitors, and hyperbaric oxygen therapy improved erectile function by antifibrotic effects and preservation of smooth muscle. ...

2008-01-01

477

Phosphorylation of sites 3 and 2 in rabbit skeletal muscle glycogen synthase by a multifunctional protein kinase (ATP-citrate lyase kinase)

Nine infants (six boys, three girls) with anorectal anomalies were examined in the immediate newborn period, prior to corrective surgery, with MRI. Three high, one intermediate and five low anomalies were found at MRI - one patient with a `low` lesion was subsequently found at surgery 2 months later to have a high anorectal anomaly. This infant had passed meconium per urethram soon after the MRI study, prompting the need for a protective colostomy and stressing the importance of a thorough clinical examination of babies with anorectal malformations. The MRI results and findings at surgery were in agreement in all other patients (n=8). Hydronephrosis was evident in two and renal agenesis in one patient. Sacrococcygeal hypoplasia was found in two and two hemivertebrae in one infant. No spinal cord lesion was identified. One fistula was evident on MRI but four were later found at surgery. Uniformly hyperintense T1 signal meconium was seen in all nine newborns, allowing for easy ...

1995-11-01

478

Pelvic CT for the prognostic evaluation of anorectal malformation

A multifunctional protein kinase, purified from rat liver as ATP-citrate lyase kinase, has been identified as a glycogen synthase kinase. This kinase catalyzed incorporation of up to 1.5 mol of and)2numberSPO4/mol of synthase subunit associated with a decrease in the glycogen synthase activity ratio from 0.85 to a value of 0.15. Approximately 65-70% of the TUPO4 was incorporated into site 3 and 30-35% into site 2 as determined by reverse phase high performance liquid chromatography. This multifunctional kinase was distinguished from glycogen synthase kinase-3 on the basis of nucleotide and protein substrate specificities. Since the phosphate contents in glycogen synthase of sites 3 and 2 are altered in diabetes and by insulin administration, the possible involvement of the multifunctional kinase was explored. Glycogen synthase purified from diabetic rabbits was phosphorylated in vitro by this multifunctional kinase at only 10% of the rate compared to synthase purified from control ...

1985-10-05

479

Morphological and molecular redescription of the myxozoan Unicapsula pflugfelderi from two teleost hosts in the Mediterranean. A review of the genus Unicapsula Davis 1924

The anatomical patterns of anorectal malformations have so far been studied according to the principles which inspire Pena's technique for the surgical treatment of anorectal anomalies. Thus, the diagnostic study of anorectal malformation has by the authors been considered a work of classification, but of identification. Among the diagnostic procedures in use in author's Institute, preoperative CT of pelvis is performed to assess the presence and to define the development of muscular sphincteric structure towards prognostic evaluation of continence, the major long-term goal. Seven patients, aged 1-30 months, with anorectal anomalies were studied with preoperative CT of the pelvis. CT scans showed well-developed sphinteric muscles in 3 patients (2 with recto-ureteral and 1 with recto-vestibular fistulas), poorly-developed muscular structure in 3 patients (with recto-vaginal, cloacal and prostatic fistulas), absence of muscular structure in 1 case (with recto-vesical ...

1989-01-01

480

British Library Electronic Table of Contents (United Kingdom)

Abstract Elongate plasmodia with myxosporean spores belonging to the genus Unicapsula, Davis, 1924 were found in the skeletal muscle of the striped seabream, Lithognathus mormyrus (L.), a candidate for the mediterranean aquaculture. The only species of Unicapsula described from the Mediterranean is Unicapsula pflugfelderi Schubert et al. 1975, which occurs in the picarel, Spicara smaris (L.). For morphological and molecular comparison of U. pflugfelderi from S. smaris with Unicapsula sp. from L. mormyrus measurements of plasmodia and spores, ultrastructural details and 18S and 28S rDNA sequences were analysed. Whereas plasmodia were 2-3 times larger in S. smaris than in L. mormyrus (length 2.47-0.81 mm; width 0.22-0.09 mm; P = 0.000), spore morphology showed minor differences and both 18S ...

2009-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

481

Magnetic resonance imaging of the hip with a pelvic phased-array surface coil: a technical note

MR imaging of experimental intramuscular hemorrhage at 0. 02 T; Contrast enhancement with Gd-DOTA

Objective. The aim of this study was to assess the capability of high-resolution images obtained with a commercially available pelvic phased-array surface coil to demonstrate normal hip anatomy. Design. We retrospectively analyzed the oblique coronal magnetic resonance (MR) images of hips of 36 consecutive patients acquired on a 1.5-T clinical imager using a pelvic phased-array coil as a receiver, a 16-20 cm field of view, and 5 mm slice thickness. Patients. Thirty-six patients were studied, age 15-81 years. There were 20 males and 16 females. Results and conclusions. The articular cartilage, cortex, superior labrum, and iliofemoral ligament were well visualized on proton density weighted fat saturation (PDF) images. The femoral and obturator vessels, obturator nerve, and various muscles were easily seen on T1-weighted images. High-resolution imaging of the hip is achievable in a reasonable amount of time using newer phased-array surface coils and may play an ...

1998-02-01

482

Local therapies to heal the penis: fact or fiction?

Intramuscular hermorrhage was induced by injecting autologous blood into the paraspinal muscle of 8 rabbits. In order to evaluate the time-dependent changes of hemorrhage observed on MRI, the animals were imaged at different stages of blood resolution at 0.02 tesla (T), and control examined with ultrasound using a 7.5 MHz linear transducer. Six inversion recovery sequences (TR=1 000 ms. TE=30 ms, and TI=18, 48, 148, 201, 302, and 398 ms) were used for the invivo calculation of T1 relaxation times. IR 1 000 (398)/30 imaging was performed before and after the Gd-DOTA administration. The hemorrhage was evident on MR images throughout the study, especially on the T2 weighted (SE 1 000/100) images. MRI showed the healing lesion longer than ultrasound. The T1 relaxation time increased during the time of resolution. Lesions on days 4 to 7 enhanced in intensity after the injection of Gd-DOTA. (orig.).

1990-09-01

483

In vitro corrosion, cytotoxicity and hemocompatibility of bulk nanocrystalline pure iron

Penile rehabilitation has been an area of intense study and debate over the last decade. Interest in this topic was stimulated by the observation that erectile dysfunction remained a significant problem after radical prostatectomy despite meticulous nerve-sparing technique. Smooth muscle alterations and fibrotic changes in the penis were identified as the underlying causes of penile atrophy, veno-occlusive dysfunction, and Peyronie's-like changes that were observed after surgery. Initial observations that intracavernous injection therapies used on a regular basis postoperatively resulted in improvements in the return of spontaneous erectile function led to the development of penile rehabilitation protocols. Chronic dosing of oral type V phosphodiesterase inhibitors is now commonly used by urologists after radical prostatectomy despite a lack of convincing evidence from randomized, placebo-controlled clinical trials. Use of local therapies to heal the penis may have ...

2008-11-20

484

Fiscal 1998 industrial science and technology R and D project. Research report on R and D of genome informatics technology (Development of stable oil supply measures using complex biosystem); 1998 nendo genome informatics gijutsu kenkyu kaihtsu seika hokokusho. Fukugo seibutsukei riyo sekiyu antei kyokyu taisaku kaihatsu

Bulk nanocrystalline pure iron rods were fabricated by the equal channel angular pressure (ECAP) technique up to eight passes. The microstructure and grain size distribution, natural immersion and electrochemical corrosion in simulated body fluid, cellular responses and hemocompatibility were investigated in this study. The results indicate that nanocrystalline pure iron after severe plastic deformation (SPD) would sustain durable span duration and exhibit much stronger corrosion resistance than that of the microcrystalline pure iron. The interaction of different cell lines reveals that the nanocrystalline pure iron stimulates better proliferation of fibroblast cells and preferable promotion of endothelialization, while inhibits effectively the viability of vascular smooth muscle cells (VSMCs). The burst of red cells and adhesion of the platelets were also substantially suppressed on contact with the nanocrystalline pure iron in blood circulation. A clear ...

2010-12-01

485

Evaluation of left ventricular volumes in patients with congenital heart disease and abnormal left ventricular geometry. Comparison of MRI and transthoraic 3-dimensional echocardiography; Vergleich der transthorakalen 3D-Echokardiographie mit der MRT zur Bestimmung linksventrikulaerer Volumina bei Patienten mit pathologischer Ventrikelgeometrie aufgrund angeborener Herzfehler

This report describes the fiscal 1998 result on development of genome informatics technology. As comparative analysis technique of genes, the combination of electrophoresis and PCR was used. For improvement of the throughput and reproducibility of the technique, module- shuffling primers were used, and the multi(96)-arrayed capillary fragment analyzer was devised. The system detecting SNPs rapidly was also developed successfully. As analysis technology of DNA sequence by use of triple- stranded DNA formation, study was made on construction of long cDNA libraries, selective subtraction of specific sequences from libraries, and the basic technology of homologous cloning. Study was also made on each reaction step of IGCR technique for fast analysis, and specifications of a fluorescence transfer monitor. As modeling technique of genetic sequence information, the simulation model was developed for gene expression regulatory networks during muscle differentiation, and ...

1999-03-01

486

Dynamic {sup 31}P-MR-spectroscopy of the quadriceps muscle. Influence of sex and age on spectroscopic results; Die dynamische 31-Phosphor-Magnetresonanz-Spektroskopie des M. quadriceps. Einfluss von Geschlecht und Alter auf spektroskopische Parameter

Purpose: To assess the new method of 3-dimensional echocardiography in comparison to the 'gold standard' MRI as to its ability to calculate left ventricular volumes in patients with congenital heart disease. Materials and methods: Eighteen patients between the ages of 3.9 to 37.3 years (mean: 12.8{+-}9.7) with a geometrically abnormal left ventricle were examined using a 1.5 T scanner with a fast gradient-echo sequence (TR=14 ms, TE=2.6-2.9 ms, FOV=300-400 mm, flip angle=20 , matrix=128:256, slice thickness=5 mm, retrospective gating) in multislice-multiphase technique. Transthoracic 3D-echocardiography was performed with a 3.5 MHz transducer and a Tomtec {sup trademark} (Munich, Germany) system for 3D reconstruction. Results: Volume calculation was possible in all patients with 3D-echocardiography, but the muscle mass calculation only succeeded in 11 to 18 patients (61%) due to inadequate visualization of the entire myocardium. Comparing MRI and ...

2003-07-01

487

Duration-controlled swimming exercise training induces cardiac hypertrophy in mice.

Purpose: {sup 31}P-MRS is used to assess the influence of sex and age on quadriceps muscle metabolism before and after exercise. Materials and Methods: 32 healthy volunteers (15 women, 17 men; mean age: 38{+-}17 yrs.) were examined by dynamic phosphorus-31 ({sup 31}P) magnetic resonance spectroscopy (MRS). In the magnet, the quadriceps muscle was stressed by an isometric and an isotonic form of exercise until exhaustion, respectively. Results: Resting conditions: With increasing subjects` age, the ratio {beta}-adenosine triphosphate/total phosphate decreased (r=-0.37; p=0.02). With increasing subjects` age, the ratios inorganic phosphate/phosphocreatine (r=0.79; p=5x10{sup -8}), phosphomonoester/{beta}-adenosine triphosphate (r=0.74; p=10{sup -6}) and phosphodiester/{beta}-adenosine triphosphate (r=0.62; p=10{sup -4}) increased. The pH was the only one of the evaluated spectroscopic parameters which showed a sex-dependence: Female subjects had ...

1999-05-01

488

Changes in myocardial beta1-adrenergic receptor and stimulatory G-protein gene expression after chronic treatment with doxorubicin in rat.

Exercise training associated with robust conditioning can be useful for the study of molecular mechanisms underlying exercise-induced cardiac hypertrophy. A swimming apparatus is described to control training regimens in terms of duration, load, and frequency of exercise. Mice were submitted to 60- vs 90-min session/day, once vs twice a day, with 2 or 4% of the weight of the mouse or no workload attached to the tail, for 4 vs 6 weeks of exercise training. Blood pressure was unchanged in all groups while resting heart rate decreased in the trained groups (8-18%). Skeletal muscle citrate synthase activity, measured spectrophotometrically, increased (45-58%) only as a result of duration and frequency-controlled exercise training, indicating that endurance conditioning was obtained. In groups which received duration and endurance conditioning, cardiac weight (14-25%) and myocyte dimension (13-20%) increased. The best conditioning protocol to promote physiological ...

2003-11-17

489

Action Potentials in a Giant Algal Cell: A Comparative Approach to Mechanisms and Evolution of Excitability

The gene expression of beta(1)-adrenergic receptor (beta(1)AR) and stimulatory G-protein Gsalpha in ventricle after chronic treatment with doxorubicin (DOX) in rat was investigated. The rats were treated with DOX in a dose of 2.5 mg/kg once a week for 5 weeks, the cumulative dose being 12.5 mg/kg. Two weeks after the last injection, the positive inotropic effect of isoproterenol was noticeably decreased in left atrial muscle preparations isolated from DOX-treated rats. Northern blot hybridization showed that the mRNA transcripts of beta(1)AR and Gsalpha, important signal transduction elements for regulating heart rate and contractility, were significantly decreased in the ventricle of DOX-treated rats. Thus, chronic treatment with DOX decreases the gene expression levels of myocardial beta(1)AR and Gsalpha. PMID:15353854

2004-08-01

490

Cellular Sources of Transforming Growth Factor-? Isoforms in Early and Chronic Radiation Enteropathy

The giant alga Chara corallina generates action potentials (APs) in response to mechanical stimulation, injury, or direct electrical stimulation. Students examine the waveform characteristics of these APs using standard intracellular recording techniques. Intracellular recording is easier than with neurons because of the large size of the Chara cell. Students observe very negative resting potentials (up to -250 mV), large AP amplitudes with depolarizing peaks approaching 0 mV, AP durations of seconds, and refractory periods up to several minutes. Students calculate Nernst potentials for the ions distributed across the Chara cell membrane to hypothesize the ions responsible for the resting potential and for the depolarizing phase of the AP. These calculations suggest that K+ is responsible for the resting potential and that Ca2+ influx and Ca2+-activated Cl- efflux are responsible for depolarizing phases of the AP, which they are. Comparison of the Chara AP characteristics with animal ...

2008-06-11

491

The Effect of Applied Pressure During Feeding of Critical Cast Aluminum Alloy Components With Particular Reference to Fatigue Resistance

The three mammalian transforming growth factor (TGF)-? isoforms (TGF-?1, TGF-?2, and TGF-?3) differ in their putative roles in radiation-induced fibrosis in intestine and other organs. Furthermore, tissue specificity of TGF-? action may result from temporal or spatial changes in production and/or activation. The present study examined shifts in the cell types expressing TGF-? mRNA relative to TGF-? immunoreactivity and histopathological injury during radiation enteropathy development. A 4-cm loop of rat small intestine was locally exposed to 0, 12, or 21-Gy single doses of x-irradiation. Sham-irradiated and irradiated intestine were procured 2 and 26 weeks after irradiation. Cells expressing the TGF-?1, TGF-?2, or TGF-?3 transcripts were identified by in situ hybridization with digoxigenin-labeled riboprobes. Intestinal wall TGF-? immunoreactivity was measured using computerized image analysis, and structural radiation injury was assessed by quantitative histopathology. Normal ...

1998-11-01

492

Radiation hardening of CMOS-based circuitry in SMART transmitters

the medium to long freezing range alloys of aluminum such as A356, A357, A206, 319 for example are known to exhibit dispersed porosity, which is recognized as a factor affecting ductility, fracture toughness, and fatigue resistance of light alloy castings. The local thermal environment, for example, temperature gradient and freezing from velocity, affect the mode of solidification which, along with alloy composition, heat treatment, oxide film occlusion, hydrogen content, and the extent to which the alloy contracts on solidification, combine to exert strong effects on the porosity formation in such alloys. In addition to such factors, the availability of liquid metal and its ability to flow through the partially solidified casting, which will be affect by the pressure in the liquid metal, must also be considered. The supply of molten metal will thus be controlled by the volume of the riser available for feeding the particular casting location, its solidification ...

2003-06-30

493

Potential for hot-dry-rock geothermal resources: experimental results

Process control transmitters that incorporate digital signal processing could be used advantageously in nuclear power plants; however, because such transmitters are too sensitive to radiation, they are not used. The Electric Power Research Institute sponsored work at Sandia National Laboratories under EPRI contract RP2614-58 to determine why SMART transmitters fail when exposed to radiation and to design and demonstrate SMART transmitter circuits that could tolerate radiation. The term ''SMART'' denotes transmitters that contain digital logic. Tests showed that transmitter failure was caused by failure of the complementary metal oxide semiconductors (CMOS)-integrated circuits which are used extensively in commercial transmitters. Radiation-hardened replacements were not available for the radiation-sensitive CMOS circuits. A conceptual design showed that a radiation-tolerant transmitter could be constructed. A prototype for an analog-to-digital converter subsection ...

494

Novel catalysts for methane activation. Final progress report, September 30, 1992--April 30, 1996

Hot dry rock (HDR) contains insufficient permeability and fluid for natural hydrothermal development, but water pumped in a circulation loop through a HDR reservoir (hydraulically fractured between two drill holes) is being tested and evaluated. The formation of such in situ heat transfer systems, and subsequent testing of the man-made geothermal reservoirs in the Jemez volcanic field, New Mexico have already indicated the technical feasibility of the hot dry rock (HDR) geothermal concept. Documented production history and heat-extraction data obtained during the period from 1978 to 1980 have confirmed heat transfer, low water loss, and predictable thermal drawdown models for the HDR systems. During a nine month test of closed-loop heat extraction operations, 15 x 10/sup 6/ kWh of thermal energy were produced. The effective heat-transfer area and volume of the reservoir increased due to secondary fracturing caused by thermal contraction of the reservoir rock, and ...

1982-01-01

495

Minimal Curvature Trajectories: Riemannian Geometry Concepts for Model Reduction in Chemical Kinetics

This final report summarizes the results of our research under Contract No. DE-AC22-92PC92112, Novel Catalysts for Methane Activation. In this research we prepared and tested fullerene soots for converting methane into higher hydrocarbons. We conducted the methane conversions using dehydrocoupling conditions, primarily in the temperature regimes of 600{degrees}-1000{degrees}C and atmospheric pressures. The research was divided into three sections. The first section focused on comparing fullerene soots with other forms of carbon such as acetylene black and Norit-A. We found that the fullerene soot was indeed more reactive than the other forms of carbon. However, due to its high reactivity, it was not selective. The second section focused on the effect of metals on the reactivity of the soots, including both transition metals and alkali metals. We found that potassium could enhance the selectivities of fullerene soot to higher hydrocarbons, but the effect was unique ...

1996-06-11

496

International water power and dam construction handbook

In dissipative ordinary differential equation systems different time scales cause anisotropic phase volume contraction along solution trajectories. Model reduction methods exploit this for simplifying chemical kinetics via a time scale separation into fast and slow modes. The aim is to approximate the system dynamics with a dimension-reduced model after eliminating the fast modes by enslaving them to the slow ones via computation of a slow attracting manifold. We present a novel method for computing approximations of such manifolds using trajectory-based optimization. We discuss Riemannian geometry concepts as a basis for suitable optimization criteria characterizing trajectories near slow attracting manifolds and thus provide insight into fundamental geometric properties of multiple time scale chemical kinetics. The optimization criteria correspond to a suitable mathematical formulation of "minimal relaxation" of chemical forces along reaction trajectories under ...

2009-01-01

497

Heat pump modeling in TRNSYS

The first section of this Handbook describes hydro-electric projects currently under construction or recently commissioned in a number of countries. The major part of the Handbook is devoted to lists of data relating to hydro-electric plants and hydromachinery. These include: data for 1990 submitted by national power authorities on hydro-electric and pumped-storage plants in operation, under construction or planned; more detailed data for pumped-storage plants; country by country data on the dimensions, and reservoir and electrical capacity of major dams and hydro plant; a listing of roller compacted concrete dams; a listing of the world's largest turbines giving data on the largest unit at each scheme in rank order ranging from a unit capacity of 838 MV down to 147 MV; a similar list of the largest hydrogenerators ranging from a unit capacity of 825 MVA down to 150 MVA; details of turbine and generator contracts. The handbook concludes with an address ...

1992-01-01

498

Extracting energy from hydraulically-fractured geothermal reservoirs

Versatility of the TRNSYS software program, the ease with which new components can be incorporated into the software, and its application to simulate heat pump systems was discussed. A case history was described in which the package, augmented by the addition of several recent large-scale heat pump projects, was used in calibrating a residential geothermal heat pump system at a military housing project in Fort Polk, LA. The project involved retrofitting over 4000 air source heat pumps with geothermal heat pumps in an energy savings performance contract. The calibration of the component models led to a system model which accurately predicts the performance of the geothermal heat pump. The lessons learned from the calibration exercise were used to help to predict the energy savings from one of the electric feeders at the base which serves some 200 of the 4000+ apartments. Energy savings estimates within one per cent of the actual measured post-retrofit energy ...

1997-11-01

499

Environmental hardening of a mobile-manipulator system for nuclear environments

The governing equations for heat and mass transfer were derived for hydraulically fractured geothermal reservoirs. When converted to nondimensional form it was shown that the equations can be considerably simplified. The resulting equations can be strongly influenced by the effects of buoyancy; the magnitude of the effect is measured by the ratio of the Grashof and Reynolds numbers, and the ratio of the actual permeability of the fracture and the square of the fracture gap width. Significant quantities of energy can be extracted from hydraulic fractures--even without thermal stress fracturing. The amount is limited by the size of the fracture and the low thermal conductivity of rock. The viscous pressure drop in open fractures is insignificant, and depending upon losses in piping and surface equipment, the entire system could be ''self-pumped'' due to buoyancy. Thermal contraction of the rock tends to increase the fracture gap ...

1976-01-01

500