Science.gov (United States)

Endothelial dysfunction and increased platelet aggregation may be involved in the pathogenesis of normal tissue radiation toxicity. This study assessed clopidogrel, an inhibitor of ADP-induced platelet aggregation, as a modulator of intestinal radiation injury (radiation enteropathy). Rat small intestine was exposed to 21 Gy X-radiation. Clopidogrel (20 mg/kg/day) or vehicle was administered from 2 days before to 10 days after irradiation. Structural radiation injury, neutrophil infiltration, smooth muscle cell proliferation, collagen content, and TGF-beta1 expression were assessed 2 weeks (early phase) and 26 weeks (delayed phase) after irradiation, using quantitative histology and immunohistochemistry, morphometry, and real-time fluorogenic probe RT-PCR. Irradiated intestine exhibited significant histopathologic injury, reduced mucosal surface area, vascular sclerosis, intestinal wall fibrosis, increased collagen content, and increased ...

International Nuclear Information System (INIS)

The radiographic appearance of Ewing's sarcoma was studied retrospectively in 22 patients who survived 5 years or longer after diagnosis and treatment. Expected changes from treatment, including regression of the extraosseous soft tissue mass, periostitis, and reconstitution of the cortex, occurred in all patients. Local recurrence occurred in one patient 10 years after complete remission whereas secondary osteosarcoma occurred more than 5 years after complete remission in two other cases. Both recurrent and secondary tumors presented as new lytic foci at the site of the original primary lesion. Lytic changes from radiation (radiation osteitis) may develop more than 2 years after treatment and in this sample; such findings were widely distributed in the radiation port. The authors conclude that bone remodeling and postradiation changes occur slowly over 2 years after treatment, and that any localized lysis at the primary site is suspicious for recurrence or ...

Science.gov (United States)

... mast cell staining; ref. 16). The severity of structural radiation injury was assessed using a histopathological radiation injury score ... ...

UK PubMed Central (United Kingdom)

The 5'-terminal structures of human adenovirus type 2 (Ad2) early region 2 (E2) mRNA were investigated. The E2 transcription unit has several interesting properties, including the presence of a TATA-like...Full Text Available

UK PubMed Central (United Kingdom)

Assessment of subtle changes in the primary macromolecular components of cartilage, proteoglycan (PG) and collagen, is critical for the diagnosis of early stages of osteoarthritis (OA), but...Full Text Available

UK PubMed Central (United Kingdom)

OBJECTIVEPrevious studies showed that genetic deletion or pharmacological blockade of the receptor for advanced glycation end products (RAGE) prevents the early structural changes...Full Text Available

Science.gov (United States)

Childhood anxiety is impairing and associated with later emotional disorders. Studying risk factors for child anxiety may allow earlier identification of at-risk children for prevention efforts. This study applied an ecological risk model to address how early childhood anxiety symptoms, child temperament, maternal anxiety and depression symptoms, violence exposure, and sociodemographic risk factors predict school-aged anxiety symptoms. This longitudinal, prospective study was conducted in a representative birth cohort (n = 1109). Structural equation modeling was used to examine hypothesized associations between risk factors measured in toddlerhood/preschool (age = 3.0 years) and anxiety symptoms measured in kindergarten (age = 6.0 years) and second grade (age = 8.0 years). Early child risk factors (anxiety symptoms and temperament) emerged as the most robust predictor for both parent-and child-reported anxiety outcomes and ...

DEFF Research Database (Denmark)

In this work, we address the problem of road interpretation for driver assistance based on an early cognitive vision system. The structure of a road and the relevant traf?c are interpreted in terms of ego-motion estimation of the car, independently moving objects on the road, lane markers and large scale maps of the road. We make use of temporal and spatial disambiguation mechanisms to increase the reliability of visually extracted 2D and 3D information. This information is then used to interpret the layout of the road by using lane markers that are detected via Bayesian reasoning. We also estimate the ego-motion of the car which is used to create large scale maps of the road and also to detect independently moving objects. Sample results for the presented algorithms are shown on a stereo image sequence, that has been collected from a structured road.

International Nuclear Information System (INIS)

The results of an investigation into tailed nuclei (TN) and features of dose dependence on frequency of the binuclear cells with TN in human lymphocyte cultures by cytogenetic block method upon X-ray radiation dose are presented. The frequencies of metaphases with dicentric and ring chromosomes are investigated concurrent with TN formed upon completion of first postradiation mitosis. Frequency of the appearance of binuclear cells with nuclei having outgrowth into the cytoplasmic space and arises after first mitosis in human lymphocyte culture is linear-square dependent on the X-irradiation at doses from 0.0 to 4.0 Gy. Positive correlation between frequency of cells with tailed nuclei and frequency of metaphases of first mitosis having dicentric and rings was established. Apparently, formation such TN is connected with dicentric and rings

Energy Technology Data Exchange (ETDEWEB)

Fifty-nine patients underwent free flap osteocutaneous reconstruction that consisted of flaps of the dorsum of the foot in 26 patients and iliac crest flaps in 33 with a success rate of 92 percent and a mortality rate of 1.6 percent. These flaps, which require the expertise of microvascular surgeons, are time-consuming and complicate operating room and time management, but they represent a remarkable advance in reconstruction that can facilitate cosmetic and functional recovery of the patient. In particular, they promote healing in radiation-recurrent oral cancer and represent a definitive form of management for established radionecrosis of the mandible. The large volume of tissue available with iliac crest osteocutaneous grafts permits the management of patients with extensive cancer involving the skin, mucosa, and bone, but cancer control may still be disappointing and there is a need for improved adjuvant chemotherapy protocols. This technique appears to be a dependable, repeatable, ...

Energy Technology Data Exchange (ETDEWEB)

Based on the activation theory of alkali and sulfate, the influence of compound admixtures on the properties of high-content slag cement was studied by testing the strength, pore structure, hydrates, and microstructure, Test results show that compound admixtures can obviously improve the properties of high-content slag cement. The emphasis of the present research is two-fold: substituting gypsum with anhydrite and calcining gypsum. These both can improve early and later performance.

British Library Electronic Table of Contents (United Kingdom)

This paper considers location?allocation problem in the real uncertain world and develops a possibilistic non-linear programming model to deal with this problem. Fuzzy decision making in fuzzy environment concept is used to determine possibility distribution of location and allocation variables. To solve this model, a novel approach based on genetic algorithm structure is developed. As the proposed model includes both deterministic (location) and uncertain (allocation) parameters, the developed solution algorithm uses a hybrid chromosome structure. Also, to cover continuous nature of the problem and prevent GA from early convergence, a new crossover operator is introduced. Finally, performance of the developed algorithm is evaluated by an example.

British Library Electronic Table of Contents (United Kingdom)

This paper addresses the unique structural requirements for successful conversion of tankers for floating production storage and offloading (FPSO) or floating storage and offloading (FSO) service. A description is given of the steps undertaken during two recent and very different conversions of a highly optimized 1980s VLCC to FPSO service, and a typical robust 1970s ULCC to FSO service. The paper describes the steps needed for ensuring the FPSO or FSO requirements are successfully met during conversion of the two tankers - each having its own history, e.g. date of build, original design, material choices, class society, voyage history and repairs. Firstly, the paper describes the procedure and results of an early initial structural assessment procedure on the basis of an American Bureau o...

International Nuclear Information System (INIS)

White dwarf evolution, particularly in the early phases, is not very strongly constrained by observation. Fortunately, white dwarfs undergo nonradial pulsation in three distinct regions of the H-R diagram. These pulsations provide accurate masses, surface compositional structure and rotation velocities, and help constrain other important physical properties. We demonstrate the application of the tools of stellar seismology to white dwarf evolution using the hot white dwarf star PG 1159-035 and the cool DAV (or ZZ Ceti) stars as examples. From pulsation studies, significant challenges to the theory of white dwarf evolution emerge. 44 refs.

International Nuclear Information System (INIS)

Initial design parameters and early operational results of a 50 MeV high brightness electron linear accelerator are described. The system utilizes a radio frequency electron gun operating at a frequency of 2.856 GHz and a nominal output energy of 4.5 MeV followed by two, 2#pi#/3 mode, disc loaded, traveling wave accelerating sections. The gun cathode is photo excited with short (6 psec) laser pulses giving design peak currents of a few hundred amperes. The system will be utilized to carry out infra-red FEL studies and investigation of new high gradient accelerating structures.

Energy Technology Data Exchange (ETDEWEB)

We compared the characteristics on thin-section CT images with the histological structure of thirty-four surgically resected peripheral lung lesions 30 mm or less in diameter with a greater than 50% area of GGA on thin-section CT. Pathologically, focal area of GGA corresponded to alveolar replacement growth of tumor or interstitial fibrotic thickening of inflammation. It is considered that determination of the GGA in small peripheral lung lesions on thin-section CT is useful for the diagnosis of early adenocarcinomas. (author)

British Library Electronic Table of Contents (United Kingdom)

According to the environmental Kuznets curve hypothesis, environmental degradation increases in the early stages of growth, but it eventually decreases as income exceeds a threshold level. It is thus often argued that if international trade increases incomes then it can also have a positive impact on environmental quality. So far, these hypotheses have been widely empirically tested for the developed countries. However, it is still uncertain whether positive effects of international trade on growth and on the environment may also hold in developing countries. One of the major difficulties in testing these relations in developing countries is the poor quality of environment related data. In this analysis this problem is reduced by constructing a structural equation model (SEM) with three la...

British Library Electronic Table of Contents (United Kingdom)

It is uncertain if downregulation of ?-adrenoceptor signaling pathway is promoted by an enhanced adrenergic tone at an early stage of cardiac disease, or it develops secondary to detrimental local myocardial changes in advanced heart failure. We examined the integrity of ?-adrenoceptor signaling pathway upon chronic infusion of isoproterenol, a ?-adrenoceptor agonist, at a dose producing no structural left ventricular (LV) remodeling and systolic dysfunction. Subcutaneous isoproterenol infusion (400??g?kg?1?h?1 over 16?days) to guinea pigs using osmotic minipumps produced no change in cardiac weights, LV internal dimensions, myocyte cross-sectional area, extent of interstitial fibrosis, and basal contractile function. Isolated, perfused heart preparations from isoproterenol-treated guinea ...

Energy Technology Data Exchange (ETDEWEB)

The topics of these short lectures on the subject of cyclic stress were: Microstructural mechanisms of damage accumulation under a multistage cyclic stress until incipient cracking; influence of surface decarbonizing phenomena on the failure behaviour of steel construction parts subjected to cyclic stress; thermocyclic fatigue of pipe samples of austenitic steel 1.4436; studies on surface structuring, microstructure and fatigue in LCF area. The short lectures on effects of quasi-static and creep stress were: Shear fracture in AlMg alloys as a result of local plastic instability; study of formation and growth of pores for an early recognition of damage and the course of damage in heat-resistant steels under creep test; experimental and numeric studies of the infuence of the microstructure on the course of damage during shear fractures of steel; numerical modelling of ductile fractures on the basis of micromechanical models. Under the topic of ...

CERN Document Server

We outline to the community the value of a Magellanic Clouds Survey that consists of three components: I) a complete-area, high resolution, multi-band UV-near-IR broadband survey; II) a narrowband survey in 7 key nebular filters to cover a statistically significant sample of representative HII regions and a large-area, contiguous survey of the diffuse, warm ISM; and III) a comprehensive FUV spectroscopic survey of 1300 early-type stars. The science areas enabled by such a dataset are as follows: A) assessment of massive star feedback in both HII regions and the diffuse, warm ISM; B) completion of a comprehensive study of the 30 Doradus giant extragalactic HII region (GEHR); C) development and quantitative parameterization of stellar clustering properties; D) extensive FUV studies of early-type stellar atmospheres and their energy distributions; and E) similarly extensive FUV absorption-line studies of molecular cloud ...

International Nuclear Information System (INIS)

Structural and functional responses of a benthic macroinvertebrate assemblage to pulses of the insecticide imidacloprid were assessed in outdoor stream mesocosms. Imidacloprid pulses reduced invertebrate abundance and community diversity in imidacloprid-dosed streams compared to control streams. These results correlated well with effects of imidacloprid on leaf litter decomposition and feeding rates of Pteronarcys comstocki, a stonefly, in artificial streams. Reductions in oxygen consumption of stoneflies exposed to imidacloprid were also observed in laboratory experiments. Our findings suggest that leaf litter degradation and single species responses can be sensitive ecotoxicological endpoints that can be used as early warning indicators and biomonitoring tools for pesticide contamination. The data generated illustrates the value of mesocosm experiments in environmental assessment and how the consideration of functional and ...

British Library Electronic Table of Contents (United Kingdom)

Based on the Morlet wavelet transformation and Wigner-Ville distribution (WVD), we present a wind turbine fault diagnosis method in this paper. Wind turbine can be damaged by moisture absorption, fatigue, wind gusts or lightening strikes. Due to this reason, there is an increasing need to monitor the health of these structures. Vibration analysis is the best-known technology applied in wind turbine condition monitoring, in which the time-frequency analysis techniques such as Wigner-Ville distribution (WVD) are widely used. Theoretically WVD has an infinite resolution in time-frequency domain. For early wind turbine fault signals, however, there are two main difficulties in WVD analysis. One is strong noise signals in the background and the other is cross terms in WVD itself. In this paper,...

British Library Electronic Table of Contents (United Kingdom)

The southern Alaska convergent margin contains several small belts of sedimentary and volcanic rocks metamorphosed to blueschist facies, located along the Border Ranges fault on the contact between the Wrangellia and Chugach terranes. These belts are significant in that they are the most inboard, and thus probably contain the oldest record of Triassic-Jurassic northward-directed subduction beneath Wrangellia. The Liberty Creek HP-LT schist belt is the oldest and the innermost section of the Chugach terrane. Within this belt lawsonite blueschists contains an initial high-pressure assemblage formed by lawsonite+phengite+chlorite+sphene+albite+/-apatite+/-carbonates and quartz. Epidote blueschists are composed of sodic, sodic-calcic and calcic amphiboles+epidote+phengite+chlorite+albite+sphen...

Energy Technology Data Exchange (ETDEWEB)

A variety of observations suggest that the Universe had a hot dense origin and that the pregalactic composition of the Universe was determined by nuclear reactions that occurred in the first few minutes. There is no unique hot Big Bang theory, but the simplest version produces a primeval chemical composition that is in good qualitative agreement with the abundances deduced from observation. Whether or not any Big Bang theory will provide quantitative agreement with observations depends on a variety of factors in elementary particle physics (number and masses of stable or long-lived particles, half-life of neutron, structure of grand unified theories) and from observational astronomy (present mean baryon density of the Universe, the Hubble constant and deceleration parameter). The influence of these factors on the abundances is discussed, as is the effect of departures from homogeneity and isotropy in the early Universe.

British Library Electronic Table of Contents (United Kingdom)

Tissue-engineered heart valves are prone to early structural deterioration. We hypothesize that cell?scaffold interaction and mechanical deformation results in upregulation of genes related to osteogenic/chondrogenic differentiation and thus changes extracellular matrix (ECM) composition in human bone marrow mesenchymal stem cell (hBMSC)-derived tissue-engineered grafts. hBMSC were expanded and seeded onto poly-glycolic acid/poly-lactic acid scaffold for 14 days. Seeded tissue-engineered constructs (TEC) were subjected to cyclic flexure for 24?h, whereas control TEC was maintained in roller bottles for the same duration. hBMSC, TEC, and mechanically deformed TEC were subjected to gene-array and histological analysis. Expression levels of RNA and/or protein markers related to chondrogenesis...

Energy Technology Data Exchange (ETDEWEB)

Possible accident scenarios for a fusion reactor include breaches in the vacuum or cooling system. Intruding air or steam could react with structural or plasma facing materials, possibly mobilizing radioactive isotopes. Safety assessments must consider the early dose at the site boundary from the release of these activated materials. Previous calculations have indicated that cobalt isotopes dominate dose calculations for designs using stainless steel. Values used in these calculations, however, had been largely determined by the measurement limits of the chemical analysis methodology instead of measured releases. The purpose of the current study was to refine the analytical method to reduce the limit for detecting cobalt, and then test PCA steel in air and steam between 973 and 1473 K. Goals were to obtain more accurate measurements of cobalt mobilization in terms of g/m{sup 2}{center_dot}h and insight into the mobilization mechanisms.

International Nuclear Information System (INIS)

We revisit our original papers on the burst mode of accretion by incorporating a detailed energy balance equation into a thin-disk model for the formation and evolution of circumstellar disks around low-mass protostars. Our model includes the effect of radiative cooling, viscous and shock heating, and heating due to stellar and background irradiation. Following the collapse from the prestellar phase allows us to model the early embedded phase of disk formation and evolution. During this time, the disk is susceptible to fragmentation, depending upon the properties of the initial prestellar core. Globally, we find that higher initial core angular momentum and mass content favors more fragmentation, but higher levels of background radiation can moderate the tendency to fragment. A higher rate of mass infall onto the disk than that onto the star is a necessary but not a sufficient condition for disk fragmentation. More locally, both the Toomre Q-parameter needs to be ...

UK PubMed Central (United Kingdom)

Recessive mutations of the early phase change (epc) gene in maize affect several aspects of plant development. These mutations were identified initially because of...Full Text Available

Science.gov (United States)

The progress made during the first two years of a program to study the migration of grain boundaries in ceramic oxides is reported. The principal results of the program are concerned with the structure of grain boundaries in ..cap alpha..-Al/sub 2/O/sub 3/, although important new information has also been obtained on grain boundaries in spinels and both germanlum and silicon. Attention is focused on the basal twin boundary in ..cap alpha..-Al/sub 2/O/sub 3/ which had been identified as a model interface in early work. A series of new grain boundaries exemplified by the (11anti23) twin are also discussed briefly as is the rhombohedral twin interface. Earlier results on the first-order (..sigma..=3) twin in spinel have been extended with the development of models for the computer-simulation of high-resolution TEM images of these interfaces. A study of low-angle grain boundaries in spinel is giving new insight into the effect which the large size ...

CERN Document Server

All gauge theories need ``something fixed'' even as ``something changes.'' Underlying the implementation of these ideas all major physical theories make indispensable use of an elaborately designed spacetime model as the ``something fixed,'' i.e., absolute. This model must provide at least the following sequence of structures: point set, topological space, smooth manifold, geometric manifold, base for various bundles. The ``fine structure'' of spacetime inherent in this sequence is of course empirically unobservable directly, certainly when quantum mechanics is taken into account. This issue is at the basis of the difficulties in quantizing general relativity and has been approached in many different ways. Here we review an approach taking into account the non-Boolean properties of quantum logic when forming a spacetime model. Finally, we recall how the fundamental gauge of diffeomorphisms (the issue of general covariance vs coordinate ...

Energy Technology Data Exchange (ETDEWEB)

Over one-third of Canada's coal resources occurs in the southern Canadian Rocky Mountains, with major deposits in the Front Ranges, Inner Foothills and Outer Foothills. In the Front Ranges, deposits of metallurgical and thermal, high-volatile bituminous to semi-anthracite coal occur in the Late Jurassic-Early Cretaceous Mist Mountain Formation. In the Inner Foothills of northeastern British Columbia and west-central Alberta, resources of metallurgical and thermal medium- and low-volatile bituminous coal occur in Early Cretaceous strata of the Gething and Gates Formations. In the Outer Foothills resources of thermal, high-volatile bituminous coal occur in Late Cretaceous and Paleocene strata of the Belly River Coalspur and Paskapoo Formations. The major deposits of the Front Ranges and Inner Foothills accumulated within the coastal plains of the Fernie and Moosebar-Clearwater seas. Shorelines prograded to the north and northeast into a ...

International Nuclear Information System (INIS)

A morphological survey of barred galaxies is made to investigate the frequency of occurrence, nature, and size distributions of bars, lenses, inner and outer rings, and global spiral structure. The 121 brightest available barred galaxies are examined on Sky Survey copy plates, and on deeper and larger-scale plates, with the following main results.1. Lenses and inner rings are components of major importance in barred galaxies, occurring, respectively, in 54% of SBO--SBa, and 76% of SBab--SBc galaxies. Few early-type galaxies have rings; almost no late-type ones have lenses.2. There is an intimate connection between bars and lenses: in 17 of 20 galaxies with both components, the bar exactly fills the lens in one dimension.3. We suggest that lenses originate as bars, through an unknown process which makes some bars evolve away to a nearly axisymmetric state. Several properties of the proposed process are deduced. We emphasize the possible ...

KoreaScience (Korea)

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KoreaScience (Korea)

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Science.gov (United States)

Pancreatic Cancer; Head and Neck Cancer; Breast Cancer

Energy Technology Data Exchange (ETDEWEB)

The authors have interpreted 1,400 km of industry and government multichannel seismic reflection data from eastern Lake Superior. Seismic sequences have been identified by using reflection character and reflector terminations and truncations. This framework, coupled with outcrop information, has allowed them to assign lithologic units to some of these reflectors and reconstruct the timing and geometry of structures within the basin. The authors have mapped the Base Jacobsville-Bayfield Group/Top oronto Group, Base oronto Group/Top Keweenawan volcanics, and Basement as well as several reflectors internal to these groups. Integration of gravity and magnetic data with the seismic grid permits regional mapping of faults and folds between seismic lines. In the eastern part of the basin, high-angle basement-involved reverse faults, such as the southeastern combination of the Keweenaw fault, trend NNW-SSE, while broad folds trend E-W. The Keweenaw fault is a complex ...

Energy Technology Data Exchange (ETDEWEB)

In the past, Condition Monitoring Systems (CMS) still showed weaknesses during the employment in the damage diagnosis and/or early failure detection of damages of roller bearings in transmissions of wind power plants. This is not only due to the insufficient consideration of the variable frequency of the wind power plants during the internal processing. The presently used methods of analysis result from the communication technology and are used successfully for years at frequency solid systems. Usually, only too few information are at the disposal to the supplier of CMS in order to parametrize their systems on the respective application particularly. An exact knowledge of the internal structure of the object to be diagnosed is compellingly necessary for a successful diagnosis so that a loadable statement based on the acquired measuring data base becomes possible. Furthermore, one must clarify the borders of the presently used systems. The ...

CERN Document Server

We present a large set of merger simulations of early-type disc galaxies with mass ratios of 1:1 and 3:1 and 10% of the total disc mass in gas. In contrast to the collisionless case equal-mass mergers with gas do not result in very boxy remnants which is caused by the suppression of box orbits and the change of the projected shape of minor-axis tube orbits in the more axisymmetric remnants. The isophotal shape of 3:1 remnants and the global kinematic properties of 1:1 and 3:1 remnants are only weakly affected by the presence of gas. 1:1 remnants are slowly rotating whereas 3:1 remnants are fast rotating and discy. The shape of the stellar LOSVD is strongly influenced by gas. The LOSVDs of collisionless remnants have broad leading wings while their gaseous counterparts show steep leading wings, more consistent with observations of elliptical galaxies. We show that this change is also caused by the suppressed populating of box orbits and it is amplified by the ...

CERN Document Server

Zinc-fingers, which widely exist in eukaryotic cell and play crucial roles in life processes, depend on the binding of zinc ion for their proper folding. To computationally study the zinc coupled folding of the zinc-fingers, charge transfer and metal induced protonation/deprotonation effects have to be considered. Here, by attempting to implicitly account for such effects in classical molecular dynamics and performing intensive simulations with explicit solvent for the peptides with and without zinc binding, we investigate the folding of the Cys2His2 type zinc-finger motif and the coupling between the peptide folding and zinc binding. We find that zinc ion not only stabilizes the native structure, but also participates in the whole folding process. It binds to the peptide at early stage of folding, and directs or modulates the folding and stabilizations of the component beta-hairpin and alpha-helix. Such a crucial role of zinc binding is ...

Energy Technology Data Exchange (ETDEWEB)

The Drosophila hairy gene encodes a basic helix- loop-helix protein that functions in at least two steps during Drosophila development: (1) during embryogenesis, when it partakes in the establishment of segments, and (2) during the larval stage, when it functions negatively in determining the pattern of sensory bristles on the adult fly. In the rat, a structurally homologous gene (RHL) behaves as an immediate-early gene in its response to growth factors and can, like that in Drosophila, suppress neuronal differentiation events. Here, the authors report the genomic cloning of the human hairy gene homolog (HRY). The coding region of the gene is contained within four exons. The predicted amino acid sequence reveals only four amino acid differences between the human and rat genes. Analysis of the DNA sequence 5[prime] to the coding region reveals a putatitve untranslated exon. To increase the value of the HRY gene as a genetic marker and to assess ...

Energy Technology Data Exchange (ETDEWEB)

LiFePO{sub 4} cathode materials with distinct particle sizes were prepared by a planetary ball-milling method. The effects of particle size on the morphology, thermal stability and electrochemical performance of LiFePO{sub 4} cathode materials were investigated. The ball-milling method decreased particle size, thereby reducing the length of diffusion and improving the reversibility of the lithium ion intercalation/deintercalation. It is worth noting that the small particle sample prepared using malonic acid as a carbon source achieved a high capacity of 161 mAh g{sup -1} at a 0.1 C rate and had a very flat capacity curve during the early 50 cycles. However, the big particle samples ({proportional_to}400 nm) decayed more dramatically in capacity than the small particle size samples ({proportional_to}200 nm) at high current densities. The improvement in electrode performance was mainly due to the fine particles, the small size distribution, and the increase in ...

Energy Technology Data Exchange (ETDEWEB)

Onshore and marine seismic-reflection data obtained near the Trans-Alaskan Crustal Transect (TACT), in the region of the eastern Aleutian trench and lower Cook Inlet, reveal highly reflective midcrustal layering that begins at a depth of 10-15 km within the upper plate of the Aleutian subduction zone. Beneath the continental shelf, midcrustal reflections were recorded over broad areas and occur in subhorizontal bands that are 1 to 3 s thick. The reflections extend beneath complexly deformed late Mesozoic and early Cenozoic accreted rocks that are exposed at the surface. Preliminary interpretation of seismic refraction data indicates that under the shelf the top of the reflections corresponds in depth with a sharp increase in rock velocity, from 5.9 km/s to 6.6 km/s. North and northwest of the shelf, beneath the Chugach and Kenai mountains, midcrustal features dip 20{degree}-30{degree} north or northwest, and below the Chugach Mountains, the top of the reflections ...

Energy Technology Data Exchange (ETDEWEB)

Computed tomography (CT) of the thorax shows early promise of important diagnostic advances. We believe that CT often provides information superior to that provided by standard roentgenographic techniques, is capable of significantly influencing patient management, and in selected instances, offers unique information not available by other methods. Computed tomography permits the imaging of mediastinal structures not possible with conventional roentgenographic methods and can diagnose with certainty benign mediastinal conditions such as pericardial cysts and focal or diffuse accumulations of fat. It is ideal for detecting pleural abnormalities and for displaying underlying parenchymal disease in patients with complex pleuroparenchymal shadows on conventional films. Pulmonary metastases unseen on the plain chest film can be detected with greater sensitivity than by any other method. Future applications of CT include the staging of mediastinal ...

CERN Document Server

We present results of a study of large-scale neutral hydrogen (HI) gas in nearby radio galaxies. We find that the early-type host galaxies of different types of radio sources (compact, FR-I and FR-II) appear to contain fundamentally different large-scale HI properties: enormous regular rotating disks and rings are present around the host galaxies of a significant fraction of low power compact radio sources, while no large-scale HI is detected in low power, edge-darkened FR-I radio galaxies. Preliminary results of a study of nearby powerful, edge-brightened FR-II radio galaxies show that these systems generally contain significant amounts of large-scale HI, often distributed in tail- or bridge-like structures, indicative of a recent galaxy merger or collision. Our results suggest that different types of radio galaxies may have a different formation history, which could be related to a difference in the triggering mechanism of the radio source. ...

Science.gov (United States)

We describe the Hubble Space Telescope (HST) Wide Field Camera 3 (WFC3) Early Release Science (ERS) observations in the GOODS-South field. The new WFC3 ERS data provide calibrated, drizzled mosaics with FHWM=0.07--0.15" in the near-UV (filters F225W, F275W, and F336W) and near-IR (F098W, F125W, and F160W) in typically 2 orbits per filter. Together with the existing HST/ACS GOODS-S mosaics in the BVi'z' filters, the 10-band ERS data cover 40-50 sq. arcmin to AB=26-27.0 mag (10-sigma for point sources). In this poster, we describe the: (1) scientific rationale, data taking and reduction procedures of the WFC3 ERS mosaics; (2) object cataloging and star-galaxy separation techniques used in these 10 different filters; (3) reliability and completeness of the 10-band object catalogs from the ERS mosaics; (4) object counts in 10 different filters from 0.2-1.7 microns to AB=26.0-27.0 mag; and (5) the full-color 10-band ERS images. We discuss the panchromatic ...

Science.gov (United States)

Previous investigations have shown that both the early biological response and the mechanical properties of a porous hydroxyapatite bone graft substitute are highly sensitive to its pore structure. The objective of this study was to evaluate whether the pore structure continued to influence bone integration in the medium to long term. Two screened batches of porous hydroxyapatite (PHA) designated as batch A and batch B, with porosities of approximately 60 and 80%, respectively, were selected for this study and implanted for periods of 5, 13, and 26 weeks into the lower femur of New Zealand White rabbits. Histomorphometric analysis of the absolute volume of bone ingrowth within batch A and B implants from 5 to 26 weeks showed that the absolute volume of bone ingrowth was consistently lower in batch A (10-21%), compared to batch B implants (24-31%). However, when the volume of bone ingrowth was normalised for the available ...

International Nuclear Information System (INIS)

In this review, we demonstrate the developmental appearance, structural features, and reorganization of transient cerebral zones and structures in the human fetal brain using a correlative histological and MRI analysis. The analysis of postmortem aldehyde-fixed specimens (age range: 10 postovulatory weeks to term) revealed that, at 10 postovulatory weeks, the cerebral wall already has a trilaminar appearance and consists of: (1) a ventricular zone of high cell-packing density; (2) an intermediate zone; (3) the cortical plate (in a stage of primary consolidation) with high MRI signal intensity. The anlage of the hippocampus is present as a prominent bulging in the thin limbic telencephalon. The early fetal telencephalon impar also contains the first commissural fibers and fornix bundles in the septal area. The ganglionic eminence is clearly visible as an expanded continuation of the proliferative ventricular zone. The basal ...

UK PubMed Central (United Kingdom)

Sunbed use is associated with increased risk of melanoma. Younger people might be more susceptible to the carcinogenic effects of ultraviolet radiation. We investigated the association between...Full Text Available

UK PubMed Central (United Kingdom)

AbstractStudies performed to identify early events of ovarian cancer and to establish molecular markers to support early detection and development of chemopreventive regimens have been...Full Text Available

UK PubMed Central (United Kingdom)

Cognitive rehabilitation is an effective intervention for addressing cognitive impairments in patients with schizophrenia. Previous research has shown that the early application of Cognitive...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe precise mechanisms involved in the initiation and progression of rheumatoid arthritis (RA) are not known. Early stages of RA often have non-specific symptoms, delaying...Full Text Available

UK PubMed Central (United Kingdom)

Photodynamic therapy (PDT) is an established endoscopic technique for ablating Barrett’s esophagus with high-grade dysplasia or early-stage intraepithelial neoplasia. The most common clinically...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundPeak bone mass, attained by early adulthood, is influenced by genetic and life-style factors. Early infant feeding and duration of breastfeeding in particular, associate...Full Text Available

UK PubMed Central (United Kingdom)

In both humans and songbirds, infants learn vocalizations by imitating the sounds of adult tutors with whom they interact during an early sensitive period. Vocal learning occurs in few animal taxa;...Full Text Available

UK PubMed Central (United Kingdom)

Higher plants use photoperiodic cues to regulate many aspects of development, including the transition from vegetative to floral development. The EARLY FLOWERING3 (ELF3)...Full Text Available

Science.gov (United States)

Mission losses were incurred by an early warning satellite and a Milstar-2 communications satellite when their launch vehicles malfunctioned, the first, ...

KoreaScience (Korea)

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... While the large tanks served to regulate the water temper- ature, the polypropylene aquaria served as independent experimental units. ...

Science.gov (United States)

... Abstract in early 1996 Milstar became the first geosynchronous satellife system to employ crosslinks for synchronization and syntoniulfion. ...

Science.gov (United States)

... by starting and remaining in that size hotel. Another early study, conducted by Nailon (1968) sampled three general managers ...

Energy Technology Data Exchange (ETDEWEB)

The murine 3T3-L1 fibroblast under appropriate incubation conditions differentiates into an adipocyte phenotype. This 3T3-L1 adipocyte exhibits many of the morphologic, biochemical, and insulin-responsive features of the normal rodent adipocyte. Using quantitative electron microscopic (EM) autoradiography we find that, when /sup 125/I-insulin is incubated with 3T3-L1 adipocytes, the ligand at early times of incubation localizes to the plasma membrane of the cell preferentially to microvilli and coated pits. When the incubation is continued at 37 degrees C, /sup 125/I-insulin is internalized by the cells and preferential binding to the villous surface is lost. With the internalization of the ligand, two intracellular structures become labeled, as determined by the method of hypothetical grain analysis. These include large clear, presumably endocytotic, vesicles and multivesicular bodies. Over the first hour of incubation the labeling of these ...

International Nuclear Information System (INIS)

Monitoring nuclear plants components enable to save on operation and maintenance costs by reducing incidents gravity and casual plant stoppages thank to early detection and fast diagnosis. Improving the knowledge of the behaviour of the plant will also allow to optimize maintenance and to increase plant life. In order to improve monitoring and diagnosis capabilities in nuclear power plants. Electricite de France (EDF) is extending the existing data processing chains towards automatic aided interpretation and diagnosis. Therefore, EDF has designed an integrated monitoring and diagnosis assistance system: PSAD-Poste de Surveillance et d'Aide au Diagnostic, including several monitoring functions of the main components. It integrates on-line monitoring, off-line diagnosis and knowledge based systems. PSAD stations provide homogeneous aids to diagnosis which enable plant personnel to pinpoint the mechanical behaviour of plant equipment. The objective of PSAD is to ...

Energy Technology Data Exchange (ETDEWEB)

Tectonically active basins may host a spectrum of sequence stratigraphic expressions previously considered to be spatially mutually exclusive. In low accommodation areas with high sediment supply, fourth order eustatic cyclicity results in high frequency sequence sets while within rapidly subsiding areas, time-equivalent Type-2 sequences are expressed by highly asymmetrical coarsening upward successions, resembling large parasequences. In the shallow marine Fulmar Formation, of the U.K. North Sea Central Graben a sequence boundary and overlying lowstand deposits, which illustrate the effects of laterally variable subsidence rate and intrabasinal topography on the expression of a eustatic sea-level fall, lie between the Glosense and Serratum (J54a and J54b) maximum flooding surfaces. The syn-rift physiography comprises major tilted fault blocks, with the Central Graben dipping parallel to the major faults, simulating a ramp setting. Where the throw of the faults were greatest (SE), the ...

Science.gov (United States)

Under support from the French Space Agency (CNES), a 3D+t dusty-gas model of Comet 67P/Churyumov-Gerasimenko is being developed, to compute, from the first 2014 Rosetta orbital data, the aerodynamic forces exerted on the Rosetta orbiter and on the descent lander. We report the recently developed dust dynamics part of the code. The multi-species (presently H2O and CO) gas code is optimized in terms of computational speed owing to the use of two complementary methods: (a) 3D+t Direct Simulation Monte Carlo (DSMC) runs in the non-equilibrium regions adjacent to the surface and very distant from it, and (b) solutions of the Navier-Stokes equations in-between. The model is used presently using Lamy et al. (Space Sci. Rev., 2007, 128, 23) coarse information on 67P nucleus shape and rotation, and a range of possible gas production rates Q for the early Rosetta observations at rh 3 AU (Q 1026 - 1027 s-1). In the interim version, simplifying assumptions are made with ...

Science.gov (United States)

Mission losses were incurred by an early warning satellite and a Milstar-2 communications satellite when their launch vehicles malfunctioned, the first, ...

DEFF Research Database (Denmark)

Udgivelsesdato: 2008-null

Science.gov (United States)

4) Expand to include client-server interaction (small-scale archive interactions with the goal of evaluating information management capabilities) -- Early ...

Energy Technology Data Exchange (ETDEWEB)

Four low activation alloy classes, two austenitic and two ferritic, have been incorporated into the MOTA-1B experiment in the FFTF reactor to provide an early assessment of the suitability of such alloys for reactor service.

Energy Technology Data Exchange (ETDEWEB)

This paper reviews the historical aspects of nuclear physics. The scientific aspects of the early transuranium elements are discussed and arms control measures are reviewed. 11 refs., 14 figs. (LSP)

UK PubMed Central (United Kingdom)

Weaning of beef calves is usually done abruptly and early compared to the natural weaning of the species, and is associated with simultaneous exposure of calves to a range of social and environmental...Full Text Available

UK PubMed Central (United Kingdom)

Models can be useful at many different levels when considering complex issues such as biological control of mosquitoes. At an early stage, exploratory models are valuable in exploring the characteristics...Full Text Available

UK PubMed Central (United Kingdom)

Two-way communication between the conceptus and the mother during early pregnancy is essential if the pregnancy is to survive. In this review, our primary focus is on biochemical communication...Full Text Available

Science.gov (United States)

goals for multisensor co-registration and fusion. 6 - 12.5 Km ..... Beta-Test toolkit for cyclogenesis and early evolution of cyclones ...

Science.gov (United States)

rotor flow field in which the main rotor operates. The majority of ..... early separation predicted by their CFD code was ...... Airfoil, AGARD Fluid Dynamics Panel ...

International Nuclear Information System (INIS)

... brain take place. This highly plastic period offers the possibility for

UK PubMed Central (United Kingdom)

Specialized olfactory lobe glomeruli relating to sexual or caste differences have been observed in at least five orders of insects, suggesting an early appearance of this trait in insect evolution....Full Text Available

UK PubMed Central (United Kingdom)

BackgroundAutofluorescence bronchoscopy is more sensitive than conventional bronchoscopy for detecting early airway mucosal lesions. Decreased specificity can lead...Full Text Available

UK PubMed Central (United Kingdom)

Mutations in the Drosophila gene drop-dead (drd) result in early adult lethality and neurodegeneration, but the molecular identity of the drd...Full Text Available

UK PubMed Central (United Kingdom)

Following a brief overview of the terrestrial distribution of boron in rocks, soil, and water, the history of the discovery, early utilization, and geologic origin of borate minerals is summarized....Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Apatite fission track analysis, vitrinite reflectance data, and K-Ar dating of Permian-Carboniferous and Mesozoic core samples have been successfully integrated to reconstruct the thermal and tectonic history of the Ordos basin, China. Apatite fission track ages of Carboniferous-Jurassic sedimentary rocks range between 3 and 137 Ma, and are significantly younger than the stratigraphic ages. Confined fission track lengths demonstrate exclusively mixed length distribution, indicating complex thermal history. The data suggest that the samples must have all experienced higher paleotemperatures in the past. Mean virtinite reflectance values (R{sub o}) of the Triassic rocks range from 0.61 to 1.06%, giving a high coalification gradient of 0.36%/km and suggesting a high paleothermal gradient of 57{degrees}C/km. Permian-Carboniferous rocks have R{sub o} values on the order of 1.0-3.0%, and locally up to 4.0-6.0%. Some high R{sub o} values coincide with positive gravity and magnetic anomalies. ...

Scientific Electronic Library Online (English)

Abstract in english BACKGROUND: Severe pathogenic infection triggers excessive release of cytokines as part of the massive inflammatory response associated with septic shock. OBJECTIVES: To investigate the protective effect of caffeic acid phenethye ester (CAPE) against lipopolysaccharide (LPS) induced endotoxemia, hepatic and neuronal damage and the associated systemic inflammatory response (SIR). METHODS: Fifty male Wister rats were divided into: control, LPS, and CAPE+LPS groups. Plasma c (more) oncentrations of various cytokines, including TNF-?, IL-1?, IL-1?, IL-6, IL-4, IL-10, and sICAM-1 were evaluated. In addition, the histopathological changes in the hepatic and neural cells were assessed. RESULTS: The LPS group showed high inflammatory cytokines and sICAM-1 levels reflecting the presence of SIR. Hepatocyte necrosis, apoptosis, extensive hemorrhage and inflammatory cellular infiltration together with brain astrocytes swelling, early neuron injury and ...

Energy Technology Data Exchange (ETDEWEB)

In world crude oil markets, 1987 was a year of limited recovery and relative stability after the dramatic price slide of early 1986. Both foreign and domestic crude thereafter, ending the year somewhat higher than a year ago. In contrast, product wholesale markets remained relatively stable throughout the year, while retail prices sustained a fairly steady increase. As has been the case for over a decade, major price movements in international oil markets generally reflected responses to actual or perceived changes in the policies of the Organization of Petroleum Exporting Countries (OPEC) and/or its members. The year began with prices on an upward trend, in reaction to the December 1986 OPEC meeting in which the members resolved to return to an official pricing structure (a departure from the market-based pricing of 1986), and to reduce output quotas. Prices continued to rise until August, when evidence of continued OPEC overproduction ...

Energy Technology Data Exchange (ETDEWEB)

The paper is based on a NEA study entitled `Past Trends and Current State of Nuclear Research Institutes`, which has been published in 1996. The evolution of nuclear research institutes (NRIs) in NEA countries is described from their establishment in the early fifties to present. The objectives, missions, purposes, and competences of NRIs are highlighted. Further, the resources (budget, qualified manpower, equipment such as research reactors and laboratories) are analysed, emphasising the role of the government. Country specific examples are given to illustrate different aspects of the historic evolution, present status and trends of NRIs. It is expected that the future role of NRIs will reflect the progress in nuclear science and technology and the evolving requirements of the nuclear industry with regard to safety enhancement, fuel cycle optimisation, plant life time management and extension, decommissioning of nuclear facilities and radioactive waste disposal. ...

Energy Technology Data Exchange (ETDEWEB)

In November 1995, the Australian and New Zealand Environment and Conservation Council (ANZECC, the Council of State and National Environment Ministers) adopted a National Management Plan for PCBs. This was a significant milestone in the very long saga of Australian efforts to develop public policy and management structures for dealing with persistent organochlorine wastes. The author was part of a four-person consultation panel that carried out a public involvement program to assist and inform the process of developing the National Management Plan. The program involved, among other things, visiting every state and territory of Australia at least twice. This paper describes the development and delivery of the public involvement program, including ongoing interactions with Governments. The latter is often a complex (and many would say an unduly complex) matter in the federal system, where primary responsibility for waste management resides in the individual ...

Energy Technology Data Exchange (ETDEWEB)

Provenance and paleocurrent data from synorogenic fluvial sandstones can be used to constrain theories about the timing and structural style of Laramide foreland uplifts and associated basins. The Green River basin of southwestern Wyoming is a large ellipsoidal basin bounded by uplifts with diverse orientations and basement rock compositions. Sandstone from the main body of the Eocene Wasatch Formation in the Green River basin was sampled along the south and west flanks of the Rock Springs uplift. Petrographic examination and paleocurrent measurements reveal two main facies. The first facies is rich in feldspar and metamorphic rock fragments derived from the Wind River Mountains to the north. The second facies is dominated by quartz and sedimentary rock fragments, reflecting a source in the Uinta Mountains to the south. Distribution of these facies indicates that a sediment lobe extends 15 km into the basin from the Uinta Mountains. Another sediment lobe originates ...

Energy Technology Data Exchange (ETDEWEB)

For several decades most of the efforts to develop new scintillator materials have concentrated on high-light-yield inorganic single-crystals while polycrystalline ceramic scintillators, since their inception in the early 1980 s, have received relatively little attention. Nevertheless, transparent ceramics offer a promising approach to the fabrication of relatively inexpensive scintillators via a simple mechanical compaction and annealing process that eliminates single-crystal growth. Until recently, commonly accepted concepts restricted the polycrystalline ceramic approach to materials exhibiting a cubic crystal structure. Here, we report our results on the development of two novel ceramic scintillators based on the non-cubic crystalline materials: Lu SiO:Ce (LSO:Ce) and LaBr:Ce. While no evidence for texturing has been found in their ceramic microstructures, our LSO:Ce ceramics exhibit a surprisingly high level of transparency/ translucency ...

Science.gov (United States)

The Drosophila sequence-specific DNA binding protein, Adf-1, is capable of activating transcription of the alcohol dehydrogenase gene, Adh, and is implicated in the transcriptional control of other developmentally regulated genes. We have cloned the cDNA encoding Adf-1 by generating specific DNA probes deduced from partial amino acid sequence of the protein. Several cDNA clones encoding an extended open reading frame were isolated from a phage lambda library. The complete amino acid sequence of Adf-1 deduced from the longest cDNA reveals structural similarities to the putative helix-turn-helix DNA binding motif of Myb and Myb-related proteins. DNA sequence analysis of genomic clones and Northern blot analysis of mRNA suggest that Adf-1 is a single-copy gene encoding a 1.9-kb transcript. Purified recombinant Adf-1 expressed in Escherichia coli binds specifically to Adf-1 recognition sites and activates transcription of a synthetic Adh promoter in vitro in a manner ...

Science.gov (United States)

Epulopiscium sp. type B is an enormous intestinal symbiont of the surgeonfish Naso tonganus. Intracellular offspring production in Epulopiscium shares features with endospore formation. Here, we characterize the spoIIE homolog in Epulopiscium. The timing of spoIIE gene expression and presence of interacting partners suggest that the activation of ?(F) occurs early in Epulopiscium offspring development. PMID:21398534

UK PubMed Central (United Kingdom)

Three transcription units are present in the adenovirus type 2 region EII. Transcription units EIIaE and EIIaL encode the mRNA for the 72,000-dalton DNA binding protein, early and late in the lytic...Full Text Available

CERN Document Server

Recent nucleosynthesis calculations of Type II supernovae using advanced neutrino transport determine that the early neutrino winds are proton-rich. However, a fraction of the ejecta emitted at the same time is composed of neutron-rich pockets. In this paper we calculate the nucleosynthesis contribution from the neutron-rich pockets in the hot convective bubbles of a core-collapse supernova and show that they do not contribute significantly to the total nucleosynthesis.

UK PubMed Central (United Kingdom)

BackgroundApoptosis is a major mode of hematological tumor death after radiation. Early detection of apoptosis may be beneficial for cancer adaptive treatment. ^99mTc-HYNIC-annexinV...Full Text Available

Environmental Research Database

DescriptionThe overall aim of this application is to examine experimentally environmental influences on the pattern of senescence in birds. We plan to experimentally uncouple chronological age and reproductive effort and examine their effects on reproductive performance and lifespan. We also plan to examine experimentally how these relationships are influenced by nutritional conditions during early development. We will combine the organismal fitness measures of lifespan and reproductive performance with me [continued...

Science.gov (United States)

A post-accident-heat-removal structural effects analysis for the steel liner in the FFTF concrete containment structure is presented. (JWR)

Science.gov (United States)

Elution profiles of total lipoproteins, apolipoprotein B (apoB) concentrations in lipoproteins, and plasma triglyceride (TG) levels were examined in early-, late-, and non-lactating cows. Additionally, arteriovenous (A-V) differences were also measured to elucidate the uptake of TG and apoB-containing lipoproteins in mammary gland. Non-lactating cows showed three major peaks corresponding to triglyceride-rich lipoprotein (TRL), low density lipoprotein (LDL), and high density lipoprotein (HDL) fraction, whereas both early- and late-lactating cows revealed two peaks corresponding to TRL and HDL. The peak area of TRL in early- and late-lactating cows were significantly (p < 0.05) smaller than that in non-lactating cows. The plasma TG levels and apoB-48 concentrations of TRL in early- and late-lactating cows were also significantly (p < 0.01) lower. Furthermore, early lactating ...

CERN Document Server

Structural steels with improved atmospheric corrosion resistance

International Science & Technology Center (ISTC)

Determination of Special Molybdenum Alloys Optimal Structure Using the Cybernetic Method

Energy Technology Data Exchange (ETDEWEB)

The 52 papers discuss the following subjects: 1. Preparation and structural development; 2. Structural constitution; 3. Structural formation and phase transition; 4. Structure and mechanical properties; 5. Structural formation of metallic and nonmetallic materials; 6. Quantitative metallography, and 7. Quality assurance.

British Library Electronic Table of Contents (United Kingdom)

This longitudinal study examined a model of early school achievement in reading and math, as it varies by socioeconomic context, using data from the NICHD Study of Early Child Care and Youth Development. A conceptual model was tested that included features of family stress, early parenting, and school readiness, through both a single-group analysis and also a multiple-group analysis. Latent profile analysis was used to identify subgroups of more advantaged and less advantaged families. Family stress and parenting were shown to operate differently depending on the socioeconomic context, whereas child-based school readiness characteristics were shown to operate similarly across socieodemographic contexts. Implications for intervention are discussed.

British Library Electronic Table of Contents (United Kingdom)

There are no specific diagnostic tests or a gold standard method for measuring disease activity and outcome in spondyloarthropathies (SpA). Many different methods have been developed to assess the signs and symptoms in SpA. The aim of this study was to evaluate the value of scintigraphy, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and Bath Ankilosing Spondylitis Disease Activity Index (BASDAI) in the evaluation of disease activity in early axial SpA diagnosed with magnetic resonance imaging (MRI). Thirty early MRI-positive axial SpA patients (23 males, 7 females) with a median age of 35 (18?55) years and a median duration of inflammatory low back pain of 24 (8?60) months were included in the study. In the patients with sacroiliitis, the sensitivity, specificity, and pos...

British Library Electronic Table of Contents (United Kingdom)

Climate variability greatly affects animals through direct and indirect effects. Animals with slow reproductive adaptation to ecological changes such as large mammals are likely to have evolved mechanisms to anticipate early such impacts of climate variability on the environment. One of the adaptive mechanisms between reproductive costs and benefits in mammals affects parental investment through biases in sex ratio. Deer might be likely to show an early detection of climate variability because conception takes place in early autumn, but the main raising cost in deer concerns lactation, which takes place at the end of the following spring. The aim of this paper is to assess whether there is a relationship between global indices of climate variability such as El Ni?o-Southern Oscillation (EN...

UK PubMed Central (United Kingdom)

Materials and MethodsThe genomic effects of tumor-endothelial interactions in cancer are not yet well characterized. To study this interaction in breast...Full Text Available

UK PubMed Central (United Kingdom)

Over 30 months 9292 consecutive patients admitted to nine coronary care units with suspected myocardial infarction were considered for admission to a randomised double blind study comparing the effect...Full Text Available

UK PubMed Central (United Kingdom)

During germination and early growth of castor bean (Ricinus communis), all cellular constituents of the endosperm are eventually transferred to the growing embryo. The present results...Full Text Available

UK PubMed Central (United Kingdom)

Memory consolidation requires transcription and translation of new protein. Arc, an effector immediate early gene, and zif268, a regulatory transcription factor, have been implicated in synaptic plasticity...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundIn France, it is estimated that 24% of HIV-infected patients are also infected with HCV. Longitudinal studies addressing clinical and public health questions related to...Full Text Available

International Nuclear Information System (INIS)

A review is presented of the quest for superheavy elements under the following headings - early history; physical and nuclear properties unique to superheavy elements; searches in nature; terrestrial samples; extra-terrestrial samples; and searches at accelerators. 72 references. (U.K.).

UK PubMed Central (United Kingdom)

Randomized clinical trials are designed with stopping boundaries to guide data monitoring committees with their decision making concerning ongoing trials. In particular, when extremely positive results...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThere is a lack of studies considering social disparity in oral health emanating from adolescents in low-income countries. This study aimed to assess socio-demographic...Full Text Available

UK PubMed Central (United Kingdom)

Objective:This article examines relationships between reproductive onset and lifetime history of smoking, regular smoking, and nicotine dependence, and cannabis and other illicit...Full Text Available

UK PubMed Central (United Kingdom)

The Sleeping Beauty (SB) transposon system represents an important alternative to viral integrating vector systems but may, as its viral counterparts, be subject to transcriptional silencing. To investigate...Full Text Available

Wastenet

of early humanitarians, and the vivisectors turned to Rene Descartes (1596 1650 ) to justify ...A celebrated mathematician, physiologist, and psychologist, Descartes provided a general philosophy of the irrelevance of ethics to the ...Animals, according to Descartes, were insensible and irrational machines; moved, like clocks, but

UK PubMed Central (United Kingdom)

BackgroundTransarterial chemoembolization (TACE) therapy is an effective locoregional treatment in hepatocellular cancer (HCC) patients. For early modification of therapy, markers...Full Text Available

UK PubMed Central (United Kingdom)

Direct identification of group B streptococci from a selective broth medium was performed with the Phadebact streptococcus test to determine the feasibility of this technique for early detection of...Full Text Available

UK PubMed Central (United Kingdom)

Breast cancer is a progressive and potentially fatal disease that affects women of all ages. Like all progressive diseases, early and reliable diagnosis is the key for successful treatment and annihilation....Full Text Available

UK PubMed Central (United Kingdom)

A total of 626 patients undergoing a prostaglandin-induced abortion, the majority in the second trimester, have been analysed for complications occurring during inpatient treatment. Of the last 155...Full Text Available

UK PubMed Central (United Kingdom)

A 33-year-old man sustained an acute Achilles tendon rupture which was surgically repaired. Early nonweight-bearing range of motion and strengthening of the ankle and the repaired muscle unit was allowed...Full Text Available

UK PubMed Central (United Kingdom)

Cervical cancer is known to metastasize primarily by the lymphatic system. Dissemination through lymphatic vessels represents an early step in regional tumor progression, and the presence of lymphatic...Full Text Available

UK PubMed Central (United Kingdom)

Background. Detection of subjects with early chronic kidney disease (CKD) is important because some will progress up to stage 5 CKD, and most are at high risk of cardiovascular morbidity...Full Text Available

UK PubMed Central (United Kingdom)

In terms of managing thrombotic disorders, genotype-based individualized patient care emerged as early as 1994 when the association of factor V Leiden (G1691A), and later, prothrombin (G20210A),...Full Text Available

UK PubMed Central (United Kingdom)

Phenylketonuria (PKU) is a common genetic disorder in humans that arises from deficient activity of phenylalanine hydroxylase (PAH), which catalyzes the conversion of phenylalanine to tyrosine....Full Text Available

UK PubMed Central (United Kingdom)

Mucopolysaccharidosis type IIIB (MPS IIIB; Sanfilippo syndrome type B) is a metabolic disorder with devastating clinical characteristics starting in early childhood and leading to premature death. A...Full Text Available

Science.gov (United States)

The U.S. government technical report is a primary means by which the results of federally funded

UK PubMed Central (United Kingdom)

BackgroundMitochondrial dysfunction, oxidative damage and the accumulation of somatic mutations in mitochondrial DNA (mtDNA) have been associated with certain neurodegenerative disorders....Full Text Available

UK PubMed Central (United Kingdom)

BACKGROUND: Each component of metabolic syndrome (MS) conveys increased cardiovascular disease risk, but as a combination they become much more powerful. Vigorous early management of the syndrome may...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe proteomics approach termed proteome pattern analysis has been shown previously to have potential in the detection and classification of breast cancer. Here we aimed...Full Text Available

Science.gov (United States)

and antibody responses of rhesus macaques exposed to the human gammaretrovirus XMRV. J Virol. 2011 May ;85(9):4547-57. Epub 2011 Feb 16 . PubMed Surgical staging of early...

UK PubMed Central (United Kingdom)

Background:In recent years, breast cancer (BC) mortality rates have declined, reflecting advances in early detection. Prevention and management of treatment sequelae that could impair...Full Text Available

UK PubMed Central (United Kingdom)

Pancreatic islet transplantation into the liver provides a possibility to treat selected patients with brittle type 1 diabetes mellitus. However, massive early β-cell death increases the number...Full Text Available

Science.gov (United States)

Aquaculture is increasing worldwide, however we have little understanding of its impacts on marine communities. A critical element of many marine communities are seagrasses, a group of globally distributed marine angiosperms that are drivers of many abiotic and biotic processes in estuarine and mari...

UK PubMed Central (United Kingdom)

Suppressed IL-12 production and maladaptive immune activation, both of which are ameliorated by successful highly active antiretroviral therapy (HAART), are thought to play important roles in the immunopathogenesis...Full Text Available

UK PubMed Central (United Kingdom)

SynopsisEarly detection of late onset neonatal sepsis, prior to obvious and potentially catastrophic clinical signs, is an important goal in neonatal medicine. Sepsis causes a...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundRecessive mutations in guanylate cyclase-1 (Gucy2d) are associated with severe, early onset Leber congenital amaurosis-1(LCA1). Gucy2d...Full Text Available

UK PubMed Central (United Kingdom)

ContextFatigue is the most common sequela among non-small cell lung cancer (NSCLC) survivors 1–6 years post-treatment and is associated with functional limitations.Full Text Available

UK PubMed Central (United Kingdom)

BackgroundEarly exposure to ovarian hormones is considered to increase breast cancer incidence. The age at which the ovaries become functional is thus important.Full Text Available

UK PubMed Central (United Kingdom)

Zygotes of fucoid algae have long been studied as a paradigm for cell polarity. Polarity is established early in the first cell cycle and is then expressed as localized growth and invariant cell division....Full Text Available

UK PubMed Central (United Kingdom)

A clinical trial was conducted to determine whether prepartum intramammary pirlimycin reduces the proportion of nulliparous heifers with intramammary infection (IMI) during early lactation and improves...Full Text Available

UK PubMed Central (United Kingdom)

Chickens were bursectomized in ovo on days 18, 19 or 20 of incubation or within 6 h of hatch and immunized at day 28 after hatch by an intravenous injection of sheep red blood cells (SRBC). The immune...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundAllergic Contact Dermatitis (ACD) is regarded as a T-cell-mediated delayed-type hypersensitivity reaction. We studied the kinetics of the expression of CS-1 fibronectin,...Full Text Available

International Nuclear Information System (INIS)

Bone metastases of an Ewing's sarcoma were detected by magnetic resonance imaging (MRI), when bone scan, CT and plain films were still normal. This is due to the ability of MRI to detect intramedullary metastases before involvement of the cortex. (Auth.).

UK PubMed Central (United Kingdom)

Non-cemented femoral fixation in hip arthroplasty has become the standard of practice in the USA. However, recent literature has brought attention to an increasing incidence of periprosthetic femur...Full Text Available

UK PubMed Central (United Kingdom)

IntroductionFlow diversion is a new approach to the endovascular treatment of intracranial aneurysms which uses a high density mesh stent to induce sac thrombosis. These devices...Full Text Available

UK PubMed Central (United Kingdom)

Background:The present study measured longitudinal changes in bone turnover markers in elderly patients with vertebral fracture and investigated the relationship among bone turnover...Full Text Available

UK PubMed Central (United Kingdom)

A paradoxical metabolic imbalance in inorganic phosphate occurs from the early onset of diabetes and may lead to a reduction of high energy phosphates and tissue hypoxia. These changes take place in...Full Text Available

Science.gov (United States)

Contact scanner system in Wolsung NPP(model ESE-1565) is an early '70 equipment, so most of components are obsolete. To make it 100% compatible, PCBs for this system is the main object of the study. Most of components used in the system are not available ...

UK PubMed Central (United Kingdom)

In summer 2000, the Cushing/Whitney Medical Library at Yale University began a demonstration project to digitize classic articles in neurosurgery from the late 1800s and early 1900s. The objective of...Full Text Available

UK PubMed Central (United Kingdom)

Ripening of `Tydeman's Early' apples (Malus sylvestris L.) assessed by the occurrence of the respiratory climacteric was delayed by succinic acid 2,2-dimethyl hydrazide (B-9) but not...Full Text Available

UK PubMed Central (United Kingdom)

Premature circuit clotting is a major problem in daily practice of continuous renal replacement therapy (CRRT), increasing blood loss, workload, and costs. Early clotting is related to bioincompatibility,...Full Text Available

UK PubMed Central (United Kingdom)

This paper reviews the development of cerebral scintigraphy from its early days of planar imaging with simple technetium-99m labelled compounds to the recent revival of the technique in the form of...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Research on Be stars from the early work of Merrill and Struve to the present is reviewed, including recent observations from space. A number of models which have been proposed to explain the Be phenomenon are discussed, and the evolutionary status of Be stars is considered. 126 references.

UK PubMed Central (United Kingdom)

BackgroundIn vitro data suggest that changes in myocardial substrate metabolism may contribute to impaired myocardial function in diabetic cardiomyopathy (DCM)....Full Text Available

UK PubMed Central (United Kingdom)

We report an unusual case of strangulated diaphragmatic (Morgagni) hernia resulting in ischaemia of the small and large bowel, which was initially diagnosed as a pneumonia. This case highlights the...Full Text Available

UK PubMed Central (United Kingdom)

In multiple sclerosis (MS), oligodendrocyte and myelin destruction lead to demyelination with subsequent axonal loss. Experimental demyelination in rodents has highlighted the activation of the subventricular...Full Text Available

UK PubMed Central (United Kingdom)

The single-stranded viral DNA of an M13 phage recombinant containing the early promoter region of SV40 was hybridized with linear, double-stranded replicative form DNA of a related M13 phage containing...Full Text Available

UK PubMed Central (United Kingdom)

IntroductionVarious multigene predictors of breast cancer clinical outcome have been commercialized, but proved to be prognostic only for hormone receptor (HR) subsets overexpressing...Full Text Available

UK PubMed Central (United Kingdom)

Thiamin(e), also known as vitamin B1, is now known to play a fundamental role in energy metabolism. Its discovery followed from the original early research on the ‘anti-beriberi factor’...Full Text Available

UK PubMed Central (United Kingdom)

Methylphenidate (MPH) is commonly prescribed in childhood and adolescence for the treatment of attention–deficit/hyperactivity disorders. In rodents, MPH exposure during preadolescence...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundPathophysiological mechanisms involved in amyotrophic lateral sclerosis (ALS) are complex and none has identified reliable markers useful in routine patient evaluation....Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Transplantation has emerged as the therapy of choice for many patients with end organ failure. One of the major goals is to tailor immunosuppressive therapy to the individual needs of every patient to balance the risk for rejection and over-immunosuppression. This will require diagnostic tools that can detect harmful processes in the allograft early, and that can be measured repeatedly. This review will consider recent advances in our understanding of the molecular nature of these processes and how this information is being utilized to design novel diagnostic assays to non-invasively monitor allografts. Highlighted is the need for large-scale prospective multi-centre studies to validate assays that show early promise in single centre studies.

Energy Technology Data Exchange (ETDEWEB)

The fact that South Africa had no commercially significant deposits of crude oil necessitated the early development of production of gasoline from coal which was present in abundance in low to medium grade in thick seams, the development of the process since the early 1950s is discussed. Both the Fischer Tropsch and Lurgi processes are used, and three large plants named Sasol One, Two, and Three have been completed. A flow diagram for the Lurgi process as used in these plants is included. Typical products and their properties resulting from the Sasol-type Synthol operation are presented in tabular form. Marketing considerations and economics of production of the Sasol products are discussed briefly. (BLM)

International Nuclear Information System (INIS)

Gallium imaging is increasingly being used for the early detection of complications in patients with AIDS. A 26-year-old homosexual man who was HIV antibody positive underwent gallium imaging for investigation of possible Pneumocystis carinii pneumonia. Widespread cutaneous focal uptake was seen, which was subsequently shown to be due to mycobacterium avium-intracellulare (MAI) septicemia. This case demonstrates the importance of whole body imaging rather than imaging target areas only, the utility of gallium imaging in aiding the early detection of clinically unsuspected disease, and shows a new pattern of gallium uptake in disseminated MAI infection.

UK PubMed Central (United Kingdom)

Approximately 65% of PSI structures report some type of ligand(s) that is bound in the crystal structure. Here, a description is given of how such ligands are handled and analyzed at the JCSG and a...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

KoreaScience (Korea)

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Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

International Nuclear Information System (INIS)

The Median Tectonic Zone (MTZ) of New Zealand is a generally north trending belt of Mesozoic subduction related I-type plutonic, volcanic, and sedimentary rocks in South Island and Stewart Island that separates Permian strata of the Eastern Province Brook Street Terrane from lower to mid Gondwana margin assemblages of the Western Province. High precision isotope dilution U/Pb ages of zircons from 30 rocks are reported. Pre-digestion leaching of zircon in hydrofluoric acid yielded significantly more concordant residues by removing common Pb and dissolving more soluble high-U domains that have been more affected by relatively recent Pb loss. The results show that MTZ magmatism ranges in age from at least Early Triassic to Early Cretaceous (247-131 Ma), with a pronounced gap in the Middle Jurassic. Triassic plutons tend to occur on the eastern side of the MTZ, and they intrude volcanic/sedimentary sequences of the MTZ in Nelson and eastern ...

Science.gov (United States)

... Accession Number : AD0618975. Title : STRUCTURE OF LIQUID NITROGEN,. Corporate Author : CALIFORNIA INST OF TECH PASADENA. ...

International Nuclear Information System (INIS)

English 2006 [1 p.] Germany Lenk, Andreas Institute of Structure Physics,

Energy Technology Data Exchange (ETDEWEB)

We summarize the Hopf algebra structure on Feynman diagrams and emphasize the interest in further algebraic structures hidden in Feynman graphs.

Energy Technology Data Exchange (ETDEWEB)

The usefulness of helical CT early phase images optimized by the SmartPrep method for evaluation of wall invasion by colorectal cancer was investigated. Between August 1997 and September 1998, CT was performed to evaluate the primary tumor and local extension in 10 consecutive patients with colorectal cancer confirmed by barium enema- and/or colonoscopy. Early-phase images were acquired by using SmartPrep application software. This method allows the optimal scan delay time to be obtained by continuous monitoring of increases in CT values after injection of contrast medium. Sections of the surgical specimens, close to the same plane as the CT images, and of the same slice thickness, were analyzed histopathologically. All 10 cancers, regardless of size, showed strong enhancement on the early-phase images (81.4-112 HU, mean: 95.1 HU). The strongly enhanced image areas on CT corresponded to the primary cancer areas on ...

International Nuclear Information System (INIS)

We derive stellar masses, ages, and star formation histories (SFHs) of massive early-type galaxies in the z = 1.237 RDCS1252.9-2927 cluster and compare them with those measured in a similarly mass-selected sample of field contemporaries drawn from the Great Observatories Origin Deep Survey South Field. Robust estimates of these parameters are obtained by comparing a large grid of composite stellar population models with 8-9 band photometry in the rest-frame near-ultraviolet, optical, and IR, thus sampling the entire relevant domain of emission of the different stellar populations. Additionally, we present new, deep U-band photometry of both fields, giving access to the critical far-ultraviolet rest frame, in order to empirically constrain the dependence of the most recent star formation processes on the environment. We also analyze the morphological properties of both samples to examine the dependence of their scaling relations on their mass and environment. We ...

Science.gov (United States)

Based on the view that major changes in the social and economic context in the United States require major policy changes related to early childhood education, this paper examines the factors supporting public policy changes and how advocates for change in early childhood education might incorporate effective strategies. The paper is presented in two parts. Part 1 reviews the research on state policy settings and the factors that tend to support policy change. This part focuses attention on the ways that state policymakers appear to learn from what is going on elsewhere and incorporate new ideas into their policy agendas. Several strategic implications for advocates of policy change are presented, such as brainstorming a list of potential obstacles to the introduction of a policy innovation or shaping the debate so the public will support change. Part 2 of the paper takes these general strategic implications and considers their relevance to ...

International Nuclear Information System (INIS)

In the beginning of 2005 several changes in the electricity and natural gas market law came into effect. This report examines the influence and impact of these changes on the behaviour and development of these markets, looking at the role and position of both the energy industry and customers. The report combines existing data with new research data collected during spring and summer 2006. Whilst the recency of the law changes, along with the simultaneous impact of other market variables limits the salience of any impact, the report nevertheless provides clear and interesting conclusions. In the electricity market, one major legislative change that came into force in the beginning of 2005 concerned the supervision of the reasonableness of electricity distribution pricing. According to the newly adopted ex ante regulation principles, the regulatory authority now determines the guidelines for reasonable pricing prior the start of a predefined regulatory period. So far, the price ...

Energy Technology Data Exchange (ETDEWEB)

The increase in world oil prices since 2003 has prompted renewed interest in producing and using liquid fuels from unconventional resources, such as biomass, oil shale, and coal. This book focuses on issues and options associated with establishing a commercial coal-to-liquids (CTL) industry within the United States. It describes the technical status, costs, and performance of methods that are available for producing liquids from coal; the key energy and environmental policy issues associated with CTL development; the impediments to early commercial experience; and the efficacy of alternative federal incentives in promoting early commercial experience. Because coal is not the only near-term option for meeting liquid-fuel needs, this book also briefly reviews the benefits and limitations of other approaches, including the development of oil shale resources, the further development of biomass resources, and increasing dependence on imported ...

Environmental Research Database

ObjectivesThe main objective of this study is to address the following specific questions: 1. Are the delayed effects of poor early diet on whole organism performance and senescence contingent on, or exacerbated by, the subsequent occurrence of compensatory growth? 2. Does the rate of growth influence levels of resting metabolism and/or oxidative stress, and if so, for how long does this persist? 3. How are the levels of early nutrition, growth, resting metabolism and oxidative stress linked to the lev [continued...]DescriptionIt is now widely appreciated that, while animals may appear to recover from periods of poor food quality or quantity experienced in early development, adverse effects may occur later in adult life. Such effects can influence the performance of complete cohorts of animals, and have important consequences for population dynamics. The reasons why such delayed effects occur across the animals' lifetimes ...

Science.gov (United States)

In the present political climate, politicians are singling out children's programs and services for budget cuts. The need for teacher education programs to prepare early childhood teachers as children's advocates is becoming ever more evident. For years, the National Association for the Education of Young Children has called for greater involvement of early childhood educators as advocates for programs and services that promote children's health and education. In teacher education programs, however, this call has largely gone unheeded. The purpose of this article is to discuss the importance of involving teacher candidates in advocacy activities and policy research, the obstacles that teacher educators can face when incorporating advocacy components into their teacher education courses and programs, and resources and strategies they can use. This discussion builds upon a motivation-obstacles-resources framework developed for adoption of ...

International Nuclear Information System (INIS)

The objective of this study is to comprehend the basic structural characteristics of box shaped mixed structures proposed for a future nuclear reactor building structure. Specimens of reinforced concrete precast panel walls of the mixed structures were prepared using ultrahigh strength materials. Two bending shear tests were conducted with a parameter of the quantity of reinforcement bars. The results include: (1) Relationship of shear stress and the angle of the structure, and (2) Failure mode. (author)

CERN Document Server

We report Sr, Pd and Ag abundances for a sample of metal-poor field giants and analyze a larger sample of Y, Zr, and Ba abundances. The [Y/Zr] and [Pd/Ag] abundance ratios are similar to those measured for the r-process-rich stars CS 22892-052 and CS 31082-001. The [Pd/Ag] ratio is larger than predicted from the solar-system r-process abundances. The constant[Y/Zr] and [Sr/Y] values in the field stars places strong limits on the contributions of the weak s-process and the main s-process to the light neutron-capture elements. Stars in the globular cluster M 15 possess lower [Y/Zr] values than the field stars. There is a large dispersion in [Y/Ba]. Because the r-process is responsible for the production of the heavy elements in the early Galaxy, these dispersions require varying light-to-heavy ratios in r-process yields.

International Nuclear Information System (INIS)

In spite of the improved imaging techniques currently available, mortality for pancreatic cancer is still high, and pancreatics is often diagnosed only in its advanced stages. The authors investigated the value of different imaging techniques - i.e., US, CT, and ERCP - for an early diagnosis, when a more effective (curative?) treatment can be suggested. Fifty-six cases of pancreatic cancer and 36 cases of chronic pancreatitis were evaluated. The results indicate that ERCP, with the help of statistical methods, is superior to US and CT not only in evaluating early neoplastic or inflammatory lesions, but also for their differential diagnosis. In the letter case, ERCP can sometimes be used as a valid alternative to fine-needle aspiration biopsy.

British Library Electronic Table of Contents (United Kingdom)

Background/Aims Serum free fatty acid (FFA) composition and abnormal fatty acid metabolism have been implicated in the pathogenesis of nonalcoholic steatohepatitis (NASH). Therefore, we determined if the serum FFA composition can provide accurate diagnosis of NASH. Methods We compared fasting serum FFA compositions in 20 patients with simple steatosis to those in 77 patients with NASH, including 65 patients with early-stage NASH. Results By univariate analysis, the proportions of serum free myristic acid (P?=?0.002) and palmitoleic acid (P?=?0.033) and the stearoyl CoA desaturase (SCD)-1 index (P?=?0.047) were significantly elevated in NASH patients in comparison to patients with simple steatosis. Only the serum free myristic acid proportion was significantly elevated in the early-stage NA...

British Library Electronic Table of Contents (United Kingdom)

This article reviews the little examined early work of the Greek Marxist and state theorist, Nicos Poulantzas (1936-1979). In his first book, Nature du choses et droit of 1965, the young scholar developed a sociology of law culled from the insights of philosophical ontology. The article sets out the central claims of that book and reflects on its place in Poulantzass intellectual development. Drawing on Heidegger, Sartre and Marx, Poulantzas proposed a species of Natural Law theory that unified `facts' and `values' by grounding legal concepts in a theory of social praxis centred on material labour. Legal categories were thus irreducible to ahistorical essences but were, rather, expressions of mankinds struggle to realize its intrinsic freedom. As we shall see, although flawed and in key re...

Energy Technology Data Exchange (ETDEWEB)

The paper-insulated low-pressure oil-filled cable invented in 1917 has been used throughout the world as the major cable system for voltages from 33kV to 525kV and experimentally to 1100kV. The proven reliability of the design is amply demonstrated by the cables installed in the early 1930s still currently in service. The inherent design of an oil-filled cable requires that the low viscosity oil is retained within a lead or aluminium sheath. Changes in oil volume due to changes in ambient temperature and load are accommodated by oil reservoirs which maintain the cable oil pressure within design limits. A microprocessor monitoring system that allows early detection and quick location of oil leaks from high voltage oil-filled cables is described.

Energy Technology Data Exchange (ETDEWEB)

The phased field development of the Lion and Panthere fields, offshore the Ivory Coast, includes a small floating production, storage, and offloading (FPSO) tanker with minimal processing capability as an early oil production system (EPS). For the long-term production scheme, the FPSO will be replaced by a converted jack up mobile offshore production system (MOPS) with full process equipment. The development also includes guyed-caisson well platforms, pipeline export for natural gas to fuel an onshore power plant, and a floating storage and offloading (FSO) tanker for oil export. Pipeline export for oil is a future possibility. This array of innovative strategies and techniques seldom has been brought together in a single project. The paper describes the development plan, early oil, jack up MOPS, and transport and installation.

Energy Technology Data Exchange (ETDEWEB)

Sheltering, evacuation and distribution of stable iodine tablets are considered to be major early emergency actions aiming at diminishing the consequences after a release of radioactive materials from nuclear power plants into the air. Whether in real situations emergency managers will act accordingly is hard to predict. Uncertainties associated with these decisions are termed 'volitional' uncertainties. These uncertainties, however, cannot be assessed by expert judgements as they express the decision at stake in an emergency situation. Uncertainties on the times to implement countermeasures and on the times for the general population to respond to these measures can be assessed by experts, as they represent 'lack-of-knowledge' uncertainties. This paper describes the difference in approach of both types of uncertainties and shows the results of expert judgements on the latter type of uncertainties in early ...

Energy Technology Data Exchange (ETDEWEB)

Two cases of focal nodular hyperplasia (FNH), in which ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MR) studies detected an atypical hemorrhagic pattern associated with an intrahepatic arterio venous malformation (AVM) around the growths, are presented. In both cases, histology demonstrated a very early regenerative stage and necrotic-hemorrhagic areas within the lesions. In these cases, the analysis of radiological findings, surgical specimens and histology seemed to confirm the pathogenetic hypothesis suggested by Wanless: in normal liver parenchyma, a ``blood steal`` phenomenon due to congenital or acquired intrahepatic AVM could cause ischemic damage, appearing as a hemorrhagic necrotic area, the extent of which depends on the degree of residual portal supply. (orig.)

British Library Electronic Table of Contents (United Kingdom)

The European sea bass Dicentrarchus labrax is a marine teleost important in Mediterranean aquaculture. The development of the entire digestive tract of D. labrax, including the pharynx, was investigated from early embryonic development to day 5 post hatching (dph), when the mouth opens. The digestive tract is initialized at stage 12 somites independently from two distinct infoldings of the endodermal sheet. In the pharyngeal region, the anterior infolding forms the pharynx and the first gill slits at stage 25 somites. The other three gill arches and slits are formed between 1 and 5 dph. Posteriorly, in the gut tube region, a posterior infolding forms the foregut, midgut and hindgut. The anus opens before hatching, at stage 28 somites. Associated organs (liver, pancreas and gall bladder) ar...

Energy Technology Data Exchange (ETDEWEB)

It was recognized from the early days of commissioning of Bruce B that Control Maintenance staff would require a level of expertise to be able to maintain Special Safety Systems in proper running order. In the early 80's this was achieved through hands on experience during the original commissioning, troubleshooting and placing of the various systems in service. Control maintenance procedures were developed and implemented as the new systems came available for commissioning, as were operating manuals,training manuals etc. Under the development of the Maintenance Manager, a Conduct of Maintenance section was organized. One of the responsibilities of this section was to develop a series of Maintenance Administrative Procedures (MAPs) that set the standards for maintenance activities including training.

British Library Electronic Table of Contents (United Kingdom)

The early Miocene Pedregoso Formation is one of the numerous formations rich in organic matter within the stratigraphic record of the Urumaco Trough, in the central area of the Falcon Basin. Due to its lithological characteristics and stratigraphic position, this formation is of great interest regarding the basin's petroliferous systems. The evaluation of various inorganic and organic geochemical parameters indicates that the organic matter is primarily of marine origin, deposited in a marine carbonate environment typical of reefal systems, under oxic-to-dysoxic conditions. The low variability in the TOC concentrations and in the distributions of the biomarkers extracted from the samples suggests that the paleoenvironmental conditions and the organic-matter supply remained approximately co...

British Library Electronic Table of Contents (United Kingdom)

For early-stage firms, successful commercialization of each new product is critically important, given the shortage of financial resources, the limited product portfolio, and small staffs typical of such firms. This paper investigates two key contributing factors for new product success in entrepreneurial firms: designing products that are appealing to target users in both form and function and designing products that can be manufactured at an attractive margin so that the new enterprise can generate much needed positive cash flow. These two practices-industrial design and cost engineering-are well studied in the context of larger, established corporations but have not been explored in the context of new ventures. This study focuses on the intensity of individual and combined adoption of d...

International Nuclear Information System (INIS)

On March 31, 1995, the US Department of Energy filed a draft application for certification of compliance with the US Environmental Protection Agency (USEPA) to show the Waste Isolation Pilot Plant's compliance with the USEPA's environmental standards, making the application the first of its kind. Demonstration of compliance is by performance assessment. This paper is an early review of the performance assessment in the draft application, by the Environmental Evaluation Group, an oversight group. The performance assessment in the draft application is incomplete. Not all relevant scenarios have been analyzed. The calculation of potential consequences often does not use experimental data but rather estimates by workers developing additional data. The final compliance application, scheduled for October 1996 needs to consider additional scenarios, and be fully based on experimental data.

British Library Electronic Table of Contents (United Kingdom)

Plants release secondary metabolites into the soil that change the chemical environment around them. Exogenous abscisic acid (ABA) is an important allelochemical whose role in successional trajectories has not been examined. We hypothesized that ABA can accumulate in the soil through successional processes and have an influence on forest dynamics. To this end, we investigated the distribution of ABA in forest communities from early to late successional stages and the response of dominant species to the gradient of ABA concentrations in three types of forests from northern to southern China. Concentrations of ABA in the soils of three forest types increased from early to late successional stages. Pioneer species? litters had the lowest ABA content, and their seed germination and seedling ea...

British Library Electronic Table of Contents (United Kingdom)

Hepatocellular carcinoma (HCC) represents a major health problem as it afflicts an increasing number of patients worldwide. Albeit most of the risk factors for HCC are known, this is a deadly syndrome with a life expectancy at the time of diagnosis of less than 1?year. Definition of the molecular principles governing the neoplastic transformation of the liver is an urgent need to facilitate the clinical management of patients, based on innovative methods to detect the disease in its early stages and on more efficient therapies. In the present study, we have combined the analysis of a murine model and human samples of HCC to identify genes differentially expressed early in the process of hepatocarcinogenesis, using a microarray-based approach. Expression of 190 genes was impaired in murine ...

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In order to perform the structural analysis and stress evaluation for frame structures in the nuclear power plants, ADAMS (AIJ Design Analysis and Modules System) has been developed by the addition of the following functions to the ICES-STRUDL system. 1. Load combination and stress evaluation on the basis of specifications for designing steel structure (issued by the Architecture Institute of Japan). 2. Combination of load and stress evaluation of piping support on the basis of the regulations of Ministry of International Trade and Industry. 3. Addition of other functions than that described above. ADAMS enables structural analysis and stress evaluation exactly and efficiently not only for a large scale structure such as the pipe whip protection structure installed inside of the primary containment vessel for many loading cases but also for a large number of ...

International Nuclear Information System (INIS)

The aim of the paper is to define and study algebraic operations closely related to the group structure on the homotopy groups of topological spaces. These are certain many-place operations on the homotopy groups. The family of these operations induces an algebraic structure on the homotopy groups, which is called an A?-group structure by analogy with the A?-structures introduced by Stasheff.

International Nuclear Information System (INIS)

It is shown that the available data on x, Q"2, and A dependence of nuclear structure functions and for their ratios (EMS effect) can be described in terms of the flucton model with rescaling of parton distributions in nuclei. The x, Q"2 and A dependence of nuclear structure functions in the cumulative range (x >1) is predicted.

UK PubMed Central (United Kingdom)

Emphasis was put on the comparative quantitative structure-activity approaches to the exploration of action mechanisms of structurally different classes of compounds showing the same type of activity...Full Text Available