UK PubMed Central (United Kingdom)

Individuals from families recruited for the Long Life Family Study (LLFS) (n= 4559) were examined and compared to individuals from other cohorts to determine whether the recruitment targeting longevity...Full Text Available

UK PubMed Central (United Kingdom)

OBJECTIVES: To assess the subjective quality of life (QOL) of family caregivers of Sudanese type-1 and type-2 diabetic outpatients, using the WHO 26-item QOL instrument, compared with a general population...Full Text Available

Science.gov (United States)

The major purpose of the Police Family Life Education Project (FLEP) is 'to develop and deliver a program that will provide police recruits and their immediate family members with stress management education that focuses on the role and responsibilities o...

UK PubMed Central (United Kingdom)

Life history theory proposes that early-life cues induce highly integrated responses in traits associated with energy partitioning, maturation, reproduction, and aging such that the individual phenotype...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

This longitudinal study examined a model of early school achievement in reading and math, as it varies by socioeconomic context, using data from the NICHD Study of Early Child Care and Youth Development. A conceptual model was tested that included features of family stress, early parenting, and school readiness, through both a single-group analysis and also a multiple-group analysis. Latent profile analysis was used to identify subgroups of more advantaged and less advantaged families. Family stress and parenting were shown to operate differently depending on the socioeconomic context, whereas child-based school readiness characteristics were shown to operate similarly across socieodemographic contexts. Implications for intervention are discussed.

UK PubMed Central (United Kingdom)

BackgroundPeak bone mass, attained by early adulthood, is influenced by genetic and life-style factors. Early infant feeding and duration of breastfeeding in particular, associate...Full Text Available

Science.gov (United States)

Home economics is a dynamic field that imparts knowledge intended to help people adapt to their environment by making effective use of human and material resources. Hence, the profession values global concerns for the environment, human rights, health, and well-being. In Nigeria, home economics teachers must also consider the role they play in programs such as family life education, poverty alleviation, and universal basic education. In particular, home economics is one of the subjects through which core messages of the country's Population and Family Life Education program are to be integrated at the secondary school level. In this article, the author discusses the outcomes of this program and provides recommendations for teachers teaching this subject. (Contains 1 table and 1 resource.)

UK PubMed Central (United Kingdom)

Paediatric palliative care is a holistic approach aimed at addressing the complex issues related to the care of children and families facing chronic life limiting illnesses. The needs of children are...Full Text Available

UK PubMed Central (United Kingdom)

Background:In recent years, breast cancer (BC) mortality rates have declined, reflecting advances in early detection. Prevention and management of treatment sequelae that could impair...Full Text Available

Science.gov (United States)

... Brill, Leiden, The Netherlands. Berra, T. M. 2001. Freshwater fish distribution. Academic Press: San Diego, CA. Berra, T. M. ... ...

UK PubMed Central (United Kingdom)

Methylphenidate (MPH) is commonly prescribed in childhood and adolescence for the treatment of attention–deficit/hyperactivity disorders. In rodents, MPH exposure during preadolescence...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

This guide accompanies the following article: Gabrielle Poeschl, `What Family Organization Tells Us about Fairness and Power in Marital Relationships', Social and Personality Compass 1/1 (2007): 557-571, 10.1111/j.1751-9004.2007.00026.x Author's Introduction One thing that often strikes me, when I talk with people, is the human capacity to accept and defend surprising aspects of the social life. Thus, we have some feeling that the separation between the domestic and the public spheres has not always existed, but we are ready to assume that in the first human groups, men went out hunting to feed their family, while women stayed in the camp to take care of the children. Even in the face of evidence to the contrary, we are reluctant to question the opinion that men and women differ in persona...

British Library Electronic Table of Contents (United Kingdom)

The last decade has produced an explosion in neuroscience research examining young children's early processing of language that has implications for education. Noninvasive, safe functional brain measurements have now been proven feasible for use with children starting at birth. In the arena of language, the neural signatures of learning can be documented at a remarkably early point in development, and these early measures predict performance in children's language and pre-reading abilities in the second, third, and fifth year of life, a finding with theoretical and educational import. There is evidence that children's early mastery of language requires learning in a social context, and this finding also has important implications for education. Evidence relating socioeconomic status (SES) ...

UK PubMed Central (United Kingdom)

The biological actions of juvenile hormones are well studied; they regulate almost all aspects of an insect’s life. However, the molecular actions of these hormones are not well understood....Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Abstract Objective:- This study explored 12-month outcome and its associations to social adjustment-related variables in patients with first-episode non-affective psychosis in Finland and Spain. Methods:- Forty-nine Finnish and 37 Spanish patients were evaluated at admission on various characteristics of social adjustment. Outcome was measured for 68 (79%) patients by the Brief Psychiatric Rating Scale, Global Assessment Scale, and Grip on Life. Results:- One-fourth of the patients experienced psychotic symptoms at follow-up. Sixty per-cent of the patients showed good global functioning and Grip on Life. In both patient groups, poor earlier global functioning, weak social network, poor Grip on Life, and psychological dependence on family of origin were associated with poor outcome. In the ...

International Nuclear Information System (INIS)

The authors determined migration timing and abundance of juvenile spring chinook salmon Oncorhynchus tshawytscha and juvenile steelhead/rainbow trout O. mykiss from three populations in the Grande Ronde River basin. Based on migration timing and abundance, two distinct life-history strategies of juvenile spring chinook and O.mykiss could be distinguished. An early migrant group left upper rearing areas from July through January with a peak in the fall. A late migrant group descended from upper rearing areas from February through June with a peak in the spring.

Energy Technology Data Exchange (ETDEWEB)

Estimation of mixed Weibull distribution by maximum likelihood estimation and other methods is frequently difficult due to unstable estimates arising from limited data. Bayesian techniques can stabilize these estimates through the priors, but there is no closed-form conjugate family for the Weibull distribution. This paper reduces the number of numeric integrations required for using Bayesian estimation on mixed Weibull situations from five to two, thus making it a more feasible approach to the typical user. It also examines the robustness of the Bayesian estimates under a variety of different prior distributions. It is found that Bayesian estimation can improve accuracy over the MLE for situations with low mixture ratios so long as the prior on the weak subpopulation's characteristic life has an expected value less than or equal to the true characteristic life.

Energy Technology Data Exchange (ETDEWEB)

ABB has developed an electric drive system featuring a high-energy, sodium-sulphur battery. The energy-to-weight ratio of this battery is four times that achieved with conventional lead-acid batteries. To recharge the battery, a charger mounted next to the motor has only to be connected to a household power socket. Road testing of electric cars is already under way, with production of commercially significant series planned for the early 1990s. The drive system will enable a typical family saloon to be driven at 120 km/h and allow a range of action of 200 km in urban traffic. (authors).

International Nuclear Information System (INIS)

During their life, intervertebral discs undergo degenerative changes which need not necessarily become lesions. Conventional X-rays do not provide information on the condition of the intervertebral discs, so MRT or CT are recommended as primary techniques as they are non-invasive. Invasive methods like myelography and especially discography should not be used unless a case is highly problematic. In infants with pains in the back, MRT should be carried out as early as possible as there is nearly always an organic cause. (orig.)

Environmental Research Database

ObjectivesThe main objective of this study is to address the following specific questions: 1. Are the delayed effects of poor early diet on whole organism performance and senescence contingent on, or exacerbated by, the subsequent occurrence of compensatory growth? 2. Does the rate of growth influence levels of resting metabolism and/or oxidative stress, and if so, for how long does this persist? 3. How are the levels of early nutrition, growth, resting metabolism and oxidative stress linked to the lev [continued...]DescriptionIt is now widely appreciated that, while animals may appear to recover from periods of poor food quality or quantity experienced in early development, adverse effects may occur later in adult life. Such effects can influence the performance of complete cohorts of animals, and have important consequences for population dynamics. The reasons why such delayed effects occur across the ...

British Library Electronic Table of Contents (United Kingdom)

Hepatocellular carcinoma (HCC) represents a major health problem as it afflicts an increasing number of patients worldwide. Albeit most of the risk factors for HCC are known, this is a deadly syndrome with a life expectancy at the time of diagnosis of less than 1?year. Definition of the molecular principles governing the neoplastic transformation of the liver is an urgent need to facilitate the clinical management of patients, based on innovative methods to detect the disease in its early stages and on more efficient therapies. In the present study, we have combined the analysis of a murine model and human samples of HCC to identify genes differentially expressed early in the process of hepatocarcinogenesis, using a microarray-based approach. Expression of 190 genes was impaired in murine ...

British Library Electronic Table of Contents (United Kingdom)

Abstract Although neonatology, the study of the newborn, is well established in medical science, psychological research on the newborn is relatively scarce. Can we justify this period as a distinct stage of human development in Psychology? This introductory article considers the unique characteristics of the neonatal period, the impact of the transition to extrauterine life, including the impact of birth itself, and the stages of brain development that characterize this period. It presents evidence of an intentional, intersubjective neonate, and uses behavioural and neuroscientific evidence to argue that the neonate's early social preferences and responses indicate a unique, sensitive, experience-expectant stage of development. The authors of this issue agree in proposing that the newborn ...

British Library Electronic Table of Contents (United Kingdom)

Alcohol dependence (AD) is clinically and etiologically heterogeneous. The goal of this study was to explore AD subtypes among a sample of 1221 participants in the Irish Affected Sib Pair Study of Alcohol Dependence, all of whom met DSM-IV criteria for AD. Variables used to identify the subtypes included major depressive disorder, antisocial personality disorder, illicit drug dependence (cannabis, sedatives, stimulants, cocaine, opioids, and hallucinogens), nicotine dependence, the personality traits of neuroticism and novelty seeking, and early alcohol use. Using latent class analysis, a 3-class solution was identified as the most parsimonious description of the data. Individuals in a Mild class were least likely to have comorbid psychopathology, whereas a severe class had highest probabi...

British Library Electronic Table of Contents (United Kingdom)

Individuals who use augmentative and alternative communication (AAC) depend on technology to meet their daily needs and form relationships. Speech generating devices (SGDs) are integral components of communication systems. Reliability of SGDs is critical for effective use in everyday life. This study examined the reliability of new SGDs and found that mean time to first failure was 42.7 (SD = 41.2) weeks and at least 40% required repairs within the first year of use. The components that most frequently broke down were touch screens, wiring, main boards, batteries, memory cards, and AC adaptors. The costs of repairing SGDs were analyzed. The clinical implications of device breakdown are identified for key stakeholders, including clients, families, service providers, funding agencies, and ma...

Science.gov (United States)

Objective: To reduce mental health symptoms and high-risk behaviors and increase social support and service utilization among street-living youth, the authors conducted a pilot study to assess the feasibility of the social enterprise intervention (SEI) at a homeless youth agency. Method: Convenience sampling was used to recruit 16 street-living youth from the agency. SEI participants received 7 months of vocational and small business training and service referrals. A comparison sample of 12 agency youth was used. Results: Findings from independent sample t tests demonstrate that SEI participants displayed significant improvements at 9 months in life satisfaction, family contact, peer support, and depressive symptoms. Conclusions: Preliminary findings suggest that the SEI was feasible within the agency setting and associated with higher mental health and social outcomes. (Contains 3 figures and 3 tables.)

Wastenet

heterogeneity bias Static models: Other models:

Science.gov (United States)

Through DNA methylation, histone modifications, and small regulatory RNAs the epigenome systematically controls gene expression during development, both in utero and throughout life. The epigenome is also a very reactive system; its labile nature allows it to sense and respond to environmental perturbations to ensure survival during fetal growth. This pliability can lead to aberrant epigenetic modifications that persist into later life and induce numerous disease states. Endocrine-disrupting compounds (EDCs) are ubiquitous chemicals that interfere with growth and development. Several EDCs also interfere with epigenetic programming. The investigation of the epigenotoxic effects of bisphenol A (BPA), an EDC used in the production of plastics and resins, has further raised concern over the impact of EDCs on the epigenome. Using the Agouti viable yellow (A(vy)) mouse model, dietary BPA exposure was shown to hypomethylate both the A(vy) and the ...

British Library Electronic Table of Contents (United Kingdom)

The period from the early eighteenth century up to 1820 witnesses a fundamental shift in the conception of the human. This shift is most clearly reflected in the soul's decline from being the essence of human life to a metaphor for the mind. At the same time, the status of the body rises from a machine to a whole organism that cannot only react but also act and think. This essay follows the discourse history of the soul from John Locke to Percy Bysshe Shelley, reflecting on the fact that the emergence of the modern scientific system at the end of the Romantic period and with it a biological conception of the human does not eventually lead to the end of the concept of soul. Rather, the soul becomes an important aesthetic concept in Romantic poetry. The analysis of the poem Epipsychidion sho...

Energy Technology Data Exchange (ETDEWEB)

A variety of observations suggest that the Universe had a hot dense origin and that the pregalactic composition of the Universe was determined by nuclear reactions that occurred in the first few minutes. There is no unique hot Big Bang theory, but the simplest version produces a primeval chemical composition that is in good qualitative agreement with the abundances deduced from observation. Whether or not any Big Bang theory will provide quantitative agreement with observations depends on a variety of factors in elementary particle physics (number and masses of stable or long-lived particles, half-life of neutron, structure of grand unified theories) and from observational astronomy (present mean baryon density of the Universe, the Hubble constant and deceleration parameter). The influence of these factors on the abundances is discussed, as is the effect of departures from homogeneity and isotropy in the early Universe.

British Library Electronic Table of Contents (United Kingdom)

Spacecraft studies of the three terrestrial planets with atmospheres have made it possible to make meaningful comparisons that shed light on their common origin and divergent evolutionary paths. Early in their histories, all three apparently had oceans and extensive volcanism; Mars and Earth, at least, had magnetic fields, and Earth, at least, had life. All three currently have climates determined by energy balance relationships involving carbon dioxide, water and aerosols, regulated by solar energy deposition, atmospheric and ocean circulation, composition, and cloud physics and chemistry. This paper addresses the extent to which current knowledge allows us to explain the observed state of each planet, its planetology, climatology and biology, within a common framework. Areas of ignorance...

International Nuclear Information System (INIS)

In recent years, Obesity (defined as Body Mass Index > 30 kg/m2) has increased its prevalence reaching epidemic levels in countries such as The United States where it has became a national health issue. In Colombia the Obesity prevalence is figured around 14%. Treatment options for Obesity include life style modifications, pharmacologist management and surgical approach (Bariatric Surgery). This article describes a patient with previous bariatric surgery, who presents abdominal pain and melena owed to isquemic process of the alimentary limb caused by an internal hernia which is a potentially lethal condition if it is not highly suspected allowing its early diagnosis and treatment

British Library Electronic Table of Contents (United Kingdom)

The paper describes, for the Hausa farmers of Gidan Jatau in northern Nigeria, the distinct ways in which they see and understand (a) their close and distant environment and (b) their bodies' anatomy and physiology. These ways result in 'another geography' - of both space and being - which, however, may no longer now have the resonance it had in the early 1970s when the author lived in Gidan Jatau for two years as a guest. At that time, the spiritual dimensions of daily life were deemed important to the health and prosperity of each person and to the farmstead as a whole. The argument is made that the urban-centred literature on the bori possession-cult neglects the ordinary, anonymous spirits of house and field. Any serious archaeology of the landscape will need insights into this 'altern...

International Nuclear Information System (INIS)

Inner ring structures are observed in about one quarter of all lenticular or spiral galaxies. Statistics of the relative frequencies of the pure ring (r) and broken ring (rs) varieties in the Second Reference Catalogue (RC2) among the different families (A, AB, B) of lenticular (L) and spiral (S) galaxies at different stages (T) along the revised Hubble sequence are presented; selection effects dependent on classification weight, apparent diameter and axis ratio are discussed. Comparisons of ring diameters D/sub r/ listed in the (First) Reference Catalogue (RC1) with independent measurements of 43 barred systems by Kormendy show good systematic agreement with a standard deviation sigma_1_2(D/sub r/) = 0'.10 and individual relative mean errors sigma(D/sub r/)/ < D/sub r/ > approx. = 5%. Axis ratios are also in good agreement with sigma_1_2(b/a) = 0.06. Comparisons of axis ratios of rings and parent galaxies show systematic trends dependent on stage T; in ...

International Nuclear Information System (INIS)

Societatea Nationala Nuclearelectrica SA is the operator of the Cernavoda nuclear power plant and the second largest energy producer in Romania, after Hidroelectrica, ensuring 18% of the internal energy demand. The production of nuclear power differs from other industrial activities through the risks it involves and through the legacy it leaves to the future generations, i.e. the nuclear waste. Taking into account these considerations, public acceptance represents a constant preoccupation for nuclear companies around the world. Corporate Social Responsibility (CSR) is a new practice in the nuclear industry. After a long tradition of involvement in the life of the local community through the Social Program for Cernavoda, Nuclearelectrica has initiated a CSR campaign with the theme 'Welcome a tree in your family', addressed to pupils and high school students from Cernavoda. By this campaign, we aimed at creating relevance, not just green lots and ...

British Library Electronic Table of Contents (United Kingdom)

As the HIV/AIDS epidemic and the spread of sexually transmitted infections (STIs) in China has come to the forefront of public health attention, female sex workers (FSWs) and their clients (CFSWs) are becoming increasingly important to HIV/STI prevention efforts. This secondary analysis uses data abstracted from the Chinese Health and Family Life Survey 1999-2000 to report prevalence rates of two STIs as well as sexual risk behaviors for CFSWs - men who paid for sex with FSWs in the past 12 months - in comparison with men who had not patronized FSWs. Among 1879 Chinese CFSWs who completed anonymous interviews and urine testing, 152 (6.3%, weighted) said they had paid for sex in the past 12 months and 18.8% of CFSWs (weighted) tested positive for gonorrhea. CFSWs were 10 times more likely t...

International Nuclear Information System (INIS)

Background and purpose: Local treatment for non-metastatic Ewing's sarcoma family tumors (ESFTs) is controversial. Results achieved in a single institution in patients with ESFT of the humerus are presented. Materials and methods: Patients treated between 1983 and 2000 for ESFT of the humerus were included. The impact of local treatment (surgery, radiotherapy or both) on outcome was assessed. Results: 55 patients: 34 males (62%); 21 females (38%); mean age: 17.9 (range: 3-40). Local treatment: surgery in 27 patients (49%), radiotherapy in 17 (31%) and surgery followed by radiotherapy in 11 (20%). After a mean follow-up of 15 years (range: 7-25 years), 27 patients (49%) remained continuously disease free, 27 (49%) relapsed and one died of chemotherapy toxicity. The local recurrence rate was 13% overall: 18% (3/17) after radiotherapy, 7% (2/27) after surgery and 19% (2/11) after surgery followed by adjuvant radiotherapy (p = ns). On the contrary, the 10-year EFS ...

UK PubMed Central (United Kingdom)

The ETS proteins are a family of transcription factors (TFs) that regulate a variety of biological processes. We made genome-wide analyses to explore the classification of the ETS gene family. We identified...Full Text Available

UK PubMed Central (United Kingdom)

This study describes instructions for after-hours care offered by family physicians' offices when patients telephone the practice. Randomly selected (n=1,680) Ontario family physicians and general practitioners...Full Text Available

DEFF Research Database (Denmark)

Retention or dispersion of larvae from the spawning grounds has been identified as one of the key processes influencing recruitment success in fish stocks. To examine the potential effects of transport on recruitment. numerical simulations were performed utilizing a three-dimensional physical oceanographic model of the Baltic Sea. Cod larvae were represented as Lagrangian drifters released in the deepwater region of the Bornholm Basin, the main spawning ground for Baltic cod. Simulations were performed for the major spawning seasons of 1993 and 1994. when annual and interannual variability of meteorological forcing was large. The principal goals of the modelling exercise were first to identify the physical processes influencing the demersal distribution of the early life stages and second to describe the transport of the pelagic stages in response to variations in windstress, thereby identifying the meteorological and hydrodynamic mechanisms ...

UK PubMed Central (United Kingdom)

Recent increases in births to unmarried parents, and the instability surrounding these relationships, have raised concerns about the possible health effects associated with changes in family...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Two automated radiometers of RRA family designed for radon concentration measurements are presented. Principal performance specifications and promising applications of the radiometers are presented.

Science.gov (United States)

One of the biggest fears and challenges a parent of a child with special needs faces is navigating the post-22 landscape. When a child hits the age of 22, the Department of Elementary and Secondary Education (DESE) is no longer required to provide daily services and support. Whatever the abilities, or disabilities, of a child, every parent has the same concerns about how their child will productively fill their days and live as independently as possible without the safety net of the DESE. One of the transition paths most frequented is entering the workforce. Public and private schools alike work to teach their students the basic skills they need to work. In fact, the national Individuals with Disabilities Education Act (IDEA) states that students must have a transition plan in formulation by the age of 16. This article describes the vocational program developed by the League School of Greater Boston which specifically addresses the challenges students, their parents, and their ...

Wastenet

Improved Education Some suggest that the full range of groups that deal with families and pets could benefit

Medline Plus

... anything wrong; it could be summertime. So just vigilance with yearly exams. If you have a family ...

Science.gov (United States)

Language: English ...

Science.gov (United States)

PMID:1799068

International Nuclear Information System (INIS)

Nuclear energy provides a third of Europe's electricity with nearly no greenhouse-gas emissions. Sustained efforts are now being conducted to harmonize regulations all over Europe through WENRA and to converge on technical nuclear safety practices within the TSO network ETSON (European Technical Safety Organizations Network). In CANDU type NPP the tritiated water occurs by the neutron bombardment of deuterium. The tritiated water vapors imply health hazard (in the critical organs of the body the water presents a 10 day average biological half-life) and the early detection in nuclear plants of tritium emissions is important because the tritiated water vapors have the same characteristics as of atmospheric water vapors. By detecting tritiated vapors, the monitoring system ensures the following objectives: (a) indicates levels of tritium generally due to heavy water leakage, (b) reduces the possibility of health hazard. In order to attain this ...

Science.gov (United States)

The GTPases comprise a protein superfamily of highly conserved molecular switches adapted to many diverse functions. These proteins are found in all domains of life and often perform essential roles in fundamental cellular processes. Analysis of data from genome sequencing projects demonstrates that bacteria possess a core of 11 universally conserved GTPases (elongation factor G and Tu, initiation factor 2, LepA, Era, Obg, ThdF/TrmE, Ffh, FtsY, EngA and YchF). Investigations aimed at understanding the function of GTPases indicate that a second conserved feature of these proteins is that they elicit their function through interaction with RNA and/or ribosomes. An emerging concept suggests that the 11 universal GTPases are either necessary for ribosome function or transmitting information from the ribosome to downstream targets for the purpose of generating specific cellular responses. Furthermore, it is suggested that progenitor GTPases were ...

Energy Technology Data Exchange (ETDEWEB)

Beginning in the 1940's and continuing through the 50's and early 60's, nuclear devices were tested by aerial detonation in the United States and other countries around the world. Cesium-137 (/sup 137/Cs) is one of the most important radionuclide by-products due to its abundance and slow decay (30-year half-life). The uptake of /sup 137/Cs in animal tissue is the result of its similarity to potassium. The somatic and genetic effects of /sup 137/Cs, along with its effect on reproductive cells, can pose great hazards to wildlife species. A reported buildup of /sup 137/Cs in white-tailed deer in the lower coastal plain of Georgia during the 1960's was followed by a gradual decline during the 1970's. Although numerous studies have involved terrestrial mammals of Georgia, few have involved aquatic mammals such as the river otter. With continued atmospheric testing by some foreign countries and the ...

Energy Technology Data Exchange (ETDEWEB)

The Girassol field is located in Angolan deep water of Block 17 and consists of large vertically stacked turbidities complexes. The reservoir extends over approximately 200 km{sup 2} and water depth ranges between 1300 and 1400 meters. In that context High Resolution 3D seismic became the most valuable tool to describe and monitor the reservoir. The field development plan took into account, through re-injection of the gas into the reservoir, Total environmental policy imposing the recycling of production gas. Monitoring of this injection was the main reason to shoot the first High Resolution 4D extremely early in the life of field. Despite the complexity of interpretation due to complex fluid situation and pressure effect, the results went way beyond expectations as the 4D images are of very high quality. Data has also been used to update and refine the reservoir flow model as well as to help deciding on the location of latest development ...

KoreaScience (Korea)

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KoreaScience (Korea)

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UK PubMed Central (United Kingdom)

In this review we attempt to reconstruct the evolutionary history of hominin life history from extant and fossil evidence. We utilize demographic life history theory and distinguish life history variables,...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Maintenance of power stations so far operated on the concept of using or extending the expected service life of a machine or plant as far as possible in order to avoid early and costly replacement. This was done by means of time-oriented maintenance, inspection and repair, otherwise called preventive maintenance. A European study on maintenance methods totals the cost of these measures at between 140 to 200 billion DM. One way of reducing these costs is 'predictive maintenance'. Estimated savings are about 8 percent or between 12 and 16 billion DM per year. Predictive maintenance identifies irregulaties of machine parts at an early point in time by means of condition monitoring and can help to cut costs: unplanned repairs can be avoided; repairs can be fitted into production schedules; production will not be disturbed to to unforeseen repairs, optimised spare part warehousing helps to cut costs. Predictive ...

British Library Electronic Table of Contents (United Kingdom)

Previous family and twin studies have indicated that Graves' disease has a heritable component. Family studies have also shown that some autoimmune disease cluster in families and genetic studies have been able to show shared susceptibility genes. In the present nation-wide study we describe familial risk for Graves' disease among parents and offspring, singleton siblings, twins and spouses with regard to age of onset, gender and number and type of affected family members. Additionally familial association of Graves' disease with any of 33 other autoimmune and related conditions was analyzed. The Swedish Multigeneration Register on 0-75-year-old subjects was linked to the Hospital Discharge Register from years 1987-2007. Standardized incidence ratios (SIRs) were calculated for individuals ...

International Nuclear Information System (INIS)

Cadmium is a non-essential heavy metal found abundantly in the environment. Children of women exposed to cadmium during pregnancy display lower motor and perceptual abilities. High cadmium body burden in children is also related to impaired intelligence and lowered school achievement. However, little is known about the molecular and cellular basis of developmental neurotoxicity in the sensitive early life stages of animals. In this study, we explore neurological deficits caused by cadmium during early embryonic stages in zebrafish by examining regionalization of the neural tube, pattern formation and cell fate determination, commitment of proneural genes and induction of neurogenesis. We show that cadmium-treated embryos developed a smaller head with unclear boundaries between the brain subdivisions, particularly in the mid-hindbrain region. Embryos display normal anterior to posterior regionalization; however, the ...

International Nuclear Information System (INIS)

Monitoring nuclear plants components enable to save on operation and maintenance costs by reducing incidents gravity and casual plant stoppages thank to early detection and fast diagnosis. Improving the knowledge of the behaviour of the plant will also allow to optimize maintenance and to increase plant life. In order to improve monitoring and diagnosis capabilities in nuclear power plants. Electricite de France (EDF) is extending the existing data processing chains towards automatic aided interpretation and diagnosis. Therefore, EDF has designed an integrated monitoring and diagnosis assistance system: PSAD-Poste de Surveillance et d'Aide au Diagnostic, including several monitoring functions of the main components. It integrates on-line monitoring, off-line diagnosis and knowledge based systems. PSAD stations provide homogeneous aids to diagnosis which enable plant personnel to pinpoint the mechanical behaviour of plant equipment. The ...

Energy Technology Data Exchange (ETDEWEB)

The US Department of Energy (DOE) is now evaluating its facility requirements in support of its cleanup mission at Hanford. One of the early findings is that the 200-Area steam plants, constructed in 1943, will not meet future space heating and process needs. Because the 200 Area will serve as the primary area for waste treatment and long-term storage, a reliable steam supply is a critical element of Hanford operations. This Analysis and Decision Document (ADD) is a preliminary review of the steam supply options available to the DOE. The ADD contains a comprehensive evaluation of the two major acquisition options: line-term versus privatization. It addresses the life-cycle costs associated with each alternative, as well as factors such as contracting requirements and the impact of market, safety, security, and regulatory issues. Specifically, this ADD documents current and future steam requirements for the 200 Area, describes alternatives ...

UK PubMed Central (United Kingdom)

The Ty transposable elements of Saccharomyces cerevisiae form a heterogeneous family within which two broad structural classes (I and II) exist. The two classes differ by two large substitutions and...Full Text Available

UK PubMed Central (United Kingdom)

The "ovalbumin Y" gene, one of three which constitute the ovalbumin gene family in chicken has been completely sequenced. The exact location of exons can be derived from the comparison with the ovalbumin...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundSupport groups have proved to be effective in reducing the burden on family caregivers of dementia patients. Nevertheless, little is known about the factors that influence...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundFamilial Adenomatous Polyposis (FAP) is caused by germline mutations in the APC (Adenomatous Polyposis Coli) gene. The vast majority of APC mutations...Full Text Available

UK PubMed Central (United Kingdom)

Genes of the S100 fused-type protein (SFTP) family are clustered within the epidermal differentiation complex and encode essential components that maintain epithelial homeostasis and barrier functions....Full Text Available

UK PubMed Central (United Kingdom)

The DNA sequences were determined for the lipoprotein lipase (LPL) gene from five unrelated Japanese patients with familial LPL deficiency. The results demonstrated that all five patients are homozygotes...Full Text Available

UK PubMed Central (United Kingdom)

Four cases of unilateral giant breasts from two unrelated families are described. Three of the patients were managed surgically. It is speculated from a review of available published reports that this...Full Text Available

UK PubMed Central (United Kingdom)

Family stress theory can explain associations between contextual stressors and parenting. However, the theory has not been tested among Mexican Americans or expanded to include cultural-contextual...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundMost rapidly evolving gene families are involved in immune responses and reproduction, two biological functions which have been assigned to the carcinoembryonic antigen...Full Text Available

UK PubMed Central (United Kingdom)

Familial defective apolipoprotein (apo) B-100 is a genetic disease that leads to hypercholesterolemia and to an increased serum concentration of low density lipoproteins that bind defectively to the...Full Text Available

UK PubMed Central (United Kingdom)

BmpA, BmpB, BmpC, and BmpD are homologous Borrelia burgdorferi lipoproteins of unknown functions, encoded by the bmp genes of paralogous chromosomal gene family 36....Full Text Available

UK PubMed Central (United Kingdom)

PurposeTo detail the highly variable ocular phenotypes of a French family affected with an autosomal dominantly inherited vitreoretinopathy and to identify the disease gene.MethodsSixteen...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

A gene designated BRCA1, implicated in the susceptibility to early-onset familial breast cancer, has recently been localized to chromosome 17q12-q21. To date, the order of DNA markers mapped within this region has been based on genetic linkage analysis. The authors report the use of multicolor fluorescence in situ hybridization to establish a physically based map of five polymorphic DNA markers and 10 cloned genes spanning this region. Three cosmid clones and Alu-PCR-Generated products derived from 12 yeast artificial chromosome clones representing each of these markers were used in two-color mapping experiments to determine an initial proximity of markers relative to each other on metaphase chromosomes. Interphase mapping was then employed to determine the order and orientation of closely spaced loci by direct visualization of fluorescent signals following hybridization of three probes, each detected in a different color. Statistical analysis ...

Energy Technology Data Exchange (ETDEWEB)

Stargardt`s disease (MIM 248200), originally described in 1909, is an autosomal recessive condition of childhood, characterized by a sudden and bilateral loss of central vision. Typically, it has an early onset (7 to 12 years), a rapidly progressive course and a poor final outcome. The central area of the retina (macula) displays pigmentary changes in a ring form with depigmentation and atrophy of the retinal pigmentary epithelium (RPE). Perimacular yellowish spots, termed fundus flavimaculatus, are observed in a high percentage of patients. We have recently reported the genetic mapping of Stargardt`s disease to chromosome 1p13. On the other hand, considering that fundus flavimaculatus (MIM 230100) is another form of fleck fundus disease, with a Stargardt-like retinal aspect but with a late-onset and a more progressive course, we decided to test the hypothesis of allelism between typical Stargardt`s disease and late-onset autosomal recessive fundus flavimaculatus. ...

Energy Technology Data Exchange (ETDEWEB)

This paper discusses the evolution of the horizontal subsea tree and its utilization in increasingly demanding applications. Initially, the Horizontal Tree was seen as a solution for wells requiring high well maintenance, such as those using electrical downhole pumps. Today, the horizontal tree is being applied to natural drive wells because of attractive whole life economics. This raises concern in a number of areas. Tubing hanger seals are permanently exposed to well fluids, and must provide high integrity sealing. This required the development of a new type of radially energized, all metal sealing system, specifically for horizontal tree applications, suitable for oil or gas service at working pressures to 15,000 psi. In addition, horizontal tree pressure integrity depends on the master valve stem, gate and bonnet seals. The need for high seal integrity also dictates that the first master valves should be integral to the main body of the tree, to maximize ...

DEFF Research Database (Denmark)

Udgivelsesdato: 2004-Apr

Wastenet

...Cummins Turbo Technologies launches new family of turbochargers for smaller diesel engines at IAA Hannover, public service, publicservice.co.uk Cummins Turbo Technologies ...launches new family of turbochargers for smaller diesel engines at IAA Hannover Cummins Turbo Technologies launches new family of turbochargers for smaller diesel engines at IAA ...Facebook Delicious Cummins Turbo Technologies launches new family of turbochargers for smaller diesel engines at IAA Hannover Cummins Turbo Technologies, a global engineering leader ...turbocharger technology, launched a new range of diesel turbochargers specifically designed for diesel engines from 2 -5 litre capacity today at IAA Hannover. Cummins ...

UK PubMed Central (United Kingdom)

Objective:To evaluate the impact of avoidable mortality on the changes in life expectancy at birth in Spain.Methods:Standard life table techniques...Full Text Available

UK PubMed Central (United Kingdom)

Recessive mutations of the early phase change (epc) gene in maize affect several aspects of plant development. These mutations were identified initially because of...Full Text Available

Science.gov (United States)

... Service life limits are established by NAVAIRINST 13130.1a. The TH-57C is nearing its service life limit and without it, the ...

Wastenet

...The RSPB: Birds by family: Owls E-mail to a friendE-newsletterContact us Home England Northern Ireland Scotland Wales About Overview Awards & recognition Contact ...Birds by family PrintHome Birds and wildlife Bird guide Birds by family Owls Owls Owls are specialised birds with round heads and rather flat ...or dished faces, with forward-facing eyes and a short, hooked bill. Most are nocturnal or crepuscular (active at dawn and dusk)... Owls are found all over the temperate and tropical parts of the world. Barn owl With heart shaped face, buff back ...

CERN Document Server

If fourth family condensates are responsible for electroweak symmetry breaking then they may also break approximate global symmetries. Among the resulting pseudo-Goldstone bosons are those that can have diquark quantum numbers. We describe the variety of diquarks and their decay modes, and we find aspects that are particular to the fourth family framework. Spectacular signatures at the LHC appear and are explored for color sextet diquarks with 600 GeV mass. We consider a simple search strategy which avoids diquark reconstruction. We also consider 350 GeV mass diquarks that are accessible at the Tevatron.

KoreaScience (Korea)

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KoreaScience (Korea)

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Science.gov (United States)

Pancreatic Cancer; Head and Neck Cancer; Breast Cancer

Energy Technology Data Exchange (ETDEWEB)

Purpose: Reconstruction of radiation doses for the thoracoabdominal babygram and the abdomen X-ray from radiographic settings and exposure data acquired at Dr. von Hauner's Kinderspital (children's hospital of the University of Munich, DvHK) between 1976 and 2007; comparison of these dose values with values reported in the literature; recommendation of a reference dose value for the thoracoabdominal babygram. Materials and Methods: The data from all X-ray examinations performed since 1976 at DvHK were stored electronically in a database. After 30 years of data collection, the database now includes 305 107 radiological examinations (radiographs and fluoroscopies), especially 1493 thoracoabdominal babygrams and 3632 abdomen X-rays of newborns and young infants. With the computer program PAeDOS, a specific dose reconstruction algorithm was developed. Results: the entrance dose values of thoracoabdominal babygrams and abdomen X-rays in DvHK could be reduced in the last 30 ...

Energy Technology Data Exchange (ETDEWEB)

The paper is based on a NEA study entitled `Past Trends and Current State of Nuclear Research Institutes`, which has been published in 1996. The evolution of nuclear research institutes (NRIs) in NEA countries is described from their establishment in the early fifties to present. The objectives, missions, purposes, and competences of NRIs are highlighted. Further, the resources (budget, qualified manpower, equipment such as research reactors and laboratories) are analysed, emphasising the role of the government. Country specific examples are given to illustrate different aspects of the historic evolution, present status and trends of NRIs. It is expected that the future role of NRIs will reflect the progress in nuclear science and technology and the evolving requirements of the nuclear industry with regard to safety enhancement, fuel cycle optimisation, plant life time management and extension, decommissioning of nuclear facilities and ...

Energy Technology Data Exchange (ETDEWEB)

Electric vehicles that can`t reach trolley wires need batteries. In the early 1900`s electric cars disappeared when owners found that replacing the car`s worn-out lead-acid battery costs more than a new gasoline-powered car. Most of today`s electric cars are still propelled by lead-acid batteries. General Motors` Impact, for example, uses starting-lighting-ignition batteries, which deliver lots of power for demonstrations, but have a life of less than 100 deep discharges. Now promising alternative technology has challenged the world-wide lead miners, refiners, and battery makers into forming a consortium that sponsors research into making better lead-acid batteries. Horizon`s new bipolar battery delivered 50 watt-hours per kg (Wh/kg), compared with 20 for ordinary transport-vehicle batteries. The alternatives are delivering from 80 Wh/kg (nickel-metal hydride) up to 200 Wh/kg (zinc-bromine). A Fiat Panda travelled 260 km on a single charge of ...

Energy Technology Data Exchange (ETDEWEB)

The primary objective of this project is to investigate the effects of global change on the biodiversity of aphid communities in Western Europe. Biodiversity has been examined at 3 levels: total number of species, phenology and reproductive strategy. Data were provided by EXAMINE, the European suction traps network which has been now operating for 35 years. 392 different species have been identified. At each location, total number of species has been regularly increasing, one additional species being caught every 1 or 2 years depending on location. This is due to introduced species but also to warming which favours rare species. No general trend of increasing density has been detected, but phenological earliness of almost all species (annual date of first appearance in suction traps) is strongly correlated with temperature and especially with mean daily temperature (during more or less long periods of time lying principally in February and March) or number of days ...

DEFF Research Database (Denmark)

Functional magnetic resonance imaging (fMRI) in young children may provide information about the development of the visual cortex, and may have predictive value for later visual performance. The purpose of this study was to evaluate the usefulness of fMRI for examining cerebral processing of vision in very young infants and in infants with brain damage. We examined 15 preterm infants, 12 children suspected of having a cerebral visual impairment and 10 children with a normal visual system, all of whom were either spontaneously asleep or sedated with chloral hydrate. Cortical response to stroboscopic light stimulation could be demonstrated in all technically acceptable data sets from children with a post-menstrual age (PMA) of > 41 weeks, but not in younger infants. Children < 60 weeks PMA showed either a blood oxygenation level-dependent (BOLD) signal increase or decrease, while all older children showed a signal decrease. The activated cortical volumes showed a linear relation to ...

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Energy Technology Data Exchange (ETDEWEB)

The effective half-life based on urine bioassay results of Wolsung NPP's worker was calculated. The effective half-life for tritiated water vapour obtained was 5 {approx} 9 days. In comparison to 10 days reported for ICRP-30, it is lower than the corresponding half-life for Reference Man. Also, the half-life was calculated based on intake amount of daily water. According to this result, the metabolism was reviewed.

Energy Technology Data Exchange (ETDEWEB)

Stars and star evolution are discussed, including supernovae, nucleosynthesis, and mass-luminosity and Hertzsprung--Russell diagrams./aip/.

KoreaScience (Korea)

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Energy Technology Data Exchange (ETDEWEB)

The Battery Life Estimator (BLE) Manual has been prepared to assist developers in their efforts to estimate the calendar life of advanced batteries for automotive applications. Testing requirements and procedures are defined by the various manuals previously published under the United States Advanced Battery Consortium (USABC). The purpose of this manual is to describe and standardize a method for estimating calendar life based on statistical models and degradation data acquired from typical USABC battery testing.

ScienceCinema

...carbon dioxide in the atmosphere contributes to global warming anything that could ...

UK PubMed Central (United Kingdom)

The objective of this study was to evaluate how the vehicles of choice affect the pharmacokinetics of orally administered Fluoranthene [FLA] in rats. Fluoranthene is a member of the family of...Full Text Available

UK PubMed Central (United Kingdom)

The receptor-associated protein (RAP) is a molecular chaperone that binds tightly to certain newly synthesized LDL receptor family members in the endoplasmic reticulum (ER) and facilitates their delivery...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

The penetrance of Lebers hereditary optic neuropathy (LHON) in families with primary mitochondrial DNA (mtDNA) mutations is very complex. Matrilineal and nuclear genetic background, as well as environmental factors, have been reported to be involved in different affected pedigrees. Here we describe two large Chinese families that show a striking difference in the penetrance of LHON, in which 53.3% and 15.0% of members were affected (Pin vivo mitochondrial oxidative metabolism as described in a previous study. Evolutionary analysis failed to indicate any putatively pathogenic mutation that cosegregated with G11778A in these two pedigrees. Our results suggest that the variable penetrance of LHON in the two Chinese families is independent of both their mtDNA haplotype background and a seconda...

UK PubMed Central (United Kingdom)

ObjectiveTo assess familial links in fat stereotypes and predictors of stereotypes among girls and their parents.Research Methods and...Full Text Available

UK PubMed Central (United Kingdom)

ObjectivesWe sought to identify a novel gene for dilated cardiomyopathy (DCM).BackgroundDCM is a heritable, genetically...Full Text Available

Science.gov (United States)

News Jobs Grants/Funding Families Prevention Diseases Regulations Preparedness Mental Health and Traumatic Events Find Local Mental Health Services Information for: Parents and...

Medline Plus

... elevated blood sugar levels, but not full-blown diabetes. What are the keys to preventing the disease? ... been well studied, in a study called The Diabetes Prevention Program, in several thousand people with this ...

UK PubMed Central (United Kingdom)

Homocysteine concentrations are a read-out of methionine metabolism and have been related to changes in lifespan in animal models. In humans, high homocysteine concentrations are an important predictor...Full Text Available

UK PubMed Central (United Kingdom)

Background and AimsAnnonaceae are one of the largest families of Magnoliales. This study investigates the comparative floral development of 15 species to understand the basis for...Full Text Available

UK PubMed Central (United Kingdom)

A 6-week-old girl with fever, hypernatraemia, dehydration, and polyuria failed to concentrate urine in response to exogenous vasopressin administration. There was no family history of nephrogenic diabetes...Full Text Available

UK PubMed Central (United Kingdom)

Background:Children of people with alcohol dependence (COAs) are at high risk for behavioral and cognitive problems.Aim:Aim of...Full Text Available

UK PubMed Central (United Kingdom)

The synapsin III gene, SYN3, which belongs to the family of synaptic vesicle-associated proteins, has been implicated in the modulation of neurotransmitter...Full Text Available

Science.gov (United States)

... each species studied are listed in Table 1. Penaeus monodon Fabricius, 1798 (family Penaeidae) and Solenocera koelbeli De Man, ... ...

Energy Technology Data Exchange (ETDEWEB)

Metagenomics projects based on shotgun sequencing of populations of micro-organisms yield insight into protein families. We used sequence similarity clustering to explore proteins with a comprehensive dataset consisting of sequences from available databases together with 6.12 million proteins predicted from an assembly of 7.7 million Global Ocean Sampling (GOS) sequences. The GOS dataset covers nearly all known prokaryotic protein families. A total of 3,995 medium- and large-sized clusters consisting of only GOS sequences are identified, out of which 1,700 have no detectable homology to known families. The GOS-only clusters contain a higher than expected proportion of sequences of viral origin, thus reflecting a poor sampling of viral diversity until now. Protein domain distributions in the GOS dataset and current protein databases show distinct biases. Several protein domains that were previously categorized as kingdom ...

UK PubMed Central (United Kingdom)

During apoptosis, the pro-apoptotic Bcl-2 family proteins BAK and BAX form large oligomeric pores in the mitochondrial outer membrane. Apoptotic factors, including cytochrome c, are...Full Text Available

CERN Document Server

The complete complementary code (CCC) is a sequence family with ideal correlation sums which was proposed by Suehiro and Hatori. Numerous literatures show its applications to direct-spread code-division multiple access (DS-CDMA) systems for inter-channel interference (ICI)-free communication with improved spectral efficiency. In this paper, we propose a systematic framework for the construction of CCCs based on $N$-shift cross-orthogonal sequence families ($N$-CO-SFs). We show theoretical bounds on the size of $N$-CO-SFs and CCCs, and give a set of four algorithms for their generation and extension. The algorithms are optimal in the sense that the size of resulted sequence families achieves theoretical bounds and, with the algorithms, we can construct an optimal CCC consisting of sequences whose lengths are not only almost arbitrary but even variable between sequence families. We also discuss the ...

British Library Electronic Table of Contents (United Kingdom)

This study was designed to identify the relationship between free time management and quality of life, exploring whether the amount of free time or the way people using their free time relates to their quality of life. Data were collected from National Pingtung University of Science and Technology in Taiwan. Of the 500 questionnaires distribute, 403 usable questionnaires were received with an 81% response rate. The result has found a positive relationship between free time management and quality of life. Contrary to this, there was no significant relationship between time allocation and quality of life. Results might indicate that people who manage their free time well lead to better quality of life. Suggestions based on the observed relationship and directions for future researches were d...

UK PubMed Central (United Kingdom)

Sunbed use is associated with increased risk of melanoma. Younger people might be more susceptible to the carcinogenic effects of ultraviolet radiation. We investigated the association between...Full Text Available

UK PubMed Central (United Kingdom)

AbstractStudies performed to identify early events of ovarian cancer and to establish molecular markers to support early detection and development of chemopreventive regimens have been...Full Text Available

UK PubMed Central (United Kingdom)

Cognitive rehabilitation is an effective intervention for addressing cognitive impairments in patients with schizophrenia. Previous research has shown that the early application of Cognitive...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe precise mechanisms involved in the initiation and progression of rheumatoid arthritis (RA) are not known. Early stages of RA often have non-specific symptoms, delaying...Full Text Available

UK PubMed Central (United Kingdom)

Photodynamic therapy (PDT) is an established endoscopic technique for ablating Barrett’s esophagus with high-grade dysplasia or early-stage intraepithelial neoplasia. The most common clinically...Full Text Available

UK PubMed Central (United Kingdom)

SUMMARYDendritic cells (DCs) in mucosal surfaces are early targets for human immunodeficiency virus-1 (HIV-1). DCs mount rapid and robust immune responses upon pathogen encounter....Full Text Available

UK PubMed Central (United Kingdom)

BackgroundOne-stage implant placement has clinically acceptable treatment outcomes. Among other advantages, it may allow investigation of early wound healing. The...Full Text Available

UK PubMed Central (United Kingdom)

Instantaneous cross sectional flow velocity profiles from early mitral flow in 10 healthy men were constructed by time interpolation of the velocity data from each point in sequentially delayed two...Full Text Available

UK PubMed Central (United Kingdom)

A public health emergency such as an influenza pandemic will lead to shortages of mechanical ventilators, critical care beds, and other potentially life saving treatments. This will raise difficult...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThere has been substantial research on psychosocial and health care determinants of health disparities in the United States (US) but less on the role of modifiable risk...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe aim of this study is to validate the questionnaire ECOS-16 (Assessment of health related quality of life in osteoporosis) for the evaluation of health related quality...Full Text Available

UK PubMed Central (United Kingdom)

A mild reduction in mitochondrial respiration extends the life span of many species, including C. elegans. We recently showed that hypoxia-inducible factor 1 (HIF-1) is required for...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundQuality of Life measurements are necessary tools for effectively evaluating health services. In the population of patients afflicted with war-related blindness in Iran,...Full Text Available

Science.gov (United States)

Probabilistic sensitivities using the score function method are developed for a lifing analysis of an alpha + beta titanium alloy in a round bar under axial fatigue load. Sensitivities with respect to the statistical inputs of the crack initiation size (a...

UK PubMed Central (United Kingdom)

ObjectiveTo report the outcome of children with life-threatening asthma (LTA) admitted to a university Pediatric Intensive Care Unit (PICU).MethodsRetrospective...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundIn a previous study conducted at the Cesare Maltoni Cancer Research Center of the European Ramazzini Foundation (CMCRC/ERF), we demonstrated for the first time that aspartame...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundHealth related quality of life (HRQoL) is one of the most important outcomes to measure effectiveness of an intervention, especially for islet transplantation...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundMigrants everywhere face several demands for health and maintaining good health and quality of life could be challenging. Iraqis are the second largest refugee group that...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe aim of the study was to develop a menopause-specific, preference-based health-related quality-of-life (HRQoL) index reflecting both menopausal symptoms and potential...Full Text Available

UK PubMed Central (United Kingdom)

The ethical dimension of treating the elderly, including risk–benefit analysis, focuses mainly on quality of life and end-of-life issues. These include arguments on advance directives and the...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe effects of intervention programs on health-related quality of life (HRQOL) of patients with hip fracture have not been well studied. We hypothesized that older patients...Full Text Available

Science.gov (United States)

Mission losses were incurred by an early warning satellite and a Milstar-2 communications satellite when their launch vehicles malfunctioned, the first, ...

KoreaScience (Korea)

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Science.gov (United States)

... While the large tanks served to regulate the water temper- ature, the polypropylene aquaria served as independent experimental units. ...

KoreaScience (Korea)

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Energy Technology Data Exchange (ETDEWEB)

The White Rose Oil Project, located in the Jeanne d'Arc Basin 350 km east of St. John's, is reported to continue paying benefits for the oil and gas industry in eastern Canada. The operator, Husky Energy, is said to be on target and expects first oil from the project in late 2005 or early 2006. Peak production for the White Rose Field is projected at 100,000 bbl/d. The project has a total capital cost of $2.35 billion. The first phase of the project, comprised of four wells, including an oil producer, was completed in July. The estimated productive capacity of this well is between 25,000 and 35,000 bbl/d. Other major milestones achieved at the White Rose project include movement of the topside modules onto the Sea Rose floating production, storage and offloading (FPSO) vessel, consisting of 17 lifts during the seven-week program. Individual lifts up to 1,250 tons were carried by the Lampson 2600 Trans-lift crane at the Cow Head Fabrication ...

International Nuclear Information System (INIS)

Sesame varieties/genotypes showed a good response to radiation with gamma rays and treatments with EMS. In M_1 both gamma rays and EMS influenced germination, seedling height, survival of plants and pollen fertility/sterility, producing deleterious effects on these characters. Compared to black seeded genotypes, white seeded ones are more susceptible to radiation. Both gamma rays and EMS produced various types of morphological variations in M_2 generation. These were dwarf plant mutants, mottled and fleshy leaved mutants (sterile), fasciated stem, flower colour, altered phyllotaxy, early, uniculm, capsule size variations, multiple capsule/leaf axil, seed coat colour variations, indehiscent and semi-indehiscent type mutants. Moreover, studies on quantitative characters including seed yield revealed the induction of mutants in both positive and negative directions for such traits which made a good scope of selection of desirable mutants in M_2 generation. Mutants ...

International Nuclear Information System (INIS)

... comparative evaluations energy-level transitions half-life internal conversion

International Nuclear Information System (INIS)

... coincidence spectrometry decay excited states gamma spectra half-life

KoreaScience (Korea)

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International Nuclear Information System (INIS)

... Safety Institute, GRS, Cologne (Germany) INIS-UA--089 456 p. APPLIED LIFE

KoreaScience (Korea)

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Energy Technology Data Exchange (ETDEWEB)

Power system components, especially components failure, can significantly affect the reliability of a power system. Data about failure rate in electrical products were obtained from products life testing and analyzed in order to predict reliability. The distribution curve fitting method was used to estimate failure probability. Ten relays of different life times have been used to illustrate the validity of this analytical technique. 3 refs., 3 tabs.

British Library Electronic Table of Contents (United Kingdom)

This study examined the life histories of a group of emerging scholars in the field of mathematics education who identify themselves as having a particular interest in and concern for issues of equity and diversity. Experiences of being the "other," "bearing witness" to "othering experiences," and "orienting experiences" in relation to issues of equity proved to be prominent themes in participants' life histories. These experiences were then linked to the positionality that these scholars now have in relation to their research in mathematics education.

International Nuclear Information System (INIS)

"1"0"1Mo is an important radionuclide to determine the burn-up of nuclear fuels, but its half-life reference values had marked differences. It is described in detail the principles and processes of the position normalization method by two high purity germanium detectors to determinate the half-life of "1"0"1Mo. (authors)

Science.gov (United States)

The need for cost effective, high performance, long life capacitors with improved reliability is discussed. It is shown that a low cost, miniature aluminum capacitor, with improved reliability and proven life, can be produced with existing technology. It is further shown that the capacitor can be specified for 125 C life and shelf test requirements, and meet established standards for their parametric performance.

Energy Technology Data Exchange (ETDEWEB)

A work on the world of astrophysics primarily for lay readers. The author writes only about the discoveries he ''experienced'' during the past 25 years (before 1979). Illustrated somewhat in color plus a set of superb colar plates. Contents, abridged: The long life of stars. The life story of the sun. The life story of massive stars. The end of stars. How stars are born. Planets and their inhabitants.

CERN Document Server

In six dimensions, cancellation of gauge, gravitational, and mixed anomalies strongly constrains the set of quantum field theories which can be coupled consistently to gravity. We show that for some classes of six-dimensional supersymmetric gauge theories coupled to gravity, the anomaly cancellation conditions are equivalent to tadpole cancellation and other constraints on the matter content of heterotic/type I compactifications on K3. In these cases, all consistent 6D supergravity theories have a realization in string theory. We find one example which may arise from a novel string compactification, and we identify a new infinite family of models satisfying anomaly factorization. We find, however, that this infinite family of models, as well as other infinite families of models previously identified by Schwarz are pathological. We suggest that it may be feasible to demonstrate that there is a string theoretic realization of ...

British Library Electronic Table of Contents (United Kingdom)

Delayed endolymphatic hydrops (DEH) is a unique disorder characterized by fluctuating otologic symptoms in the setting of preexisting unilateral deafness. The symptoms include aural fullness, fluctuating hearing, and/or episodes of vertigo similar to those observed in Meniere disease and may occur ipsilateral or contralateral to the previously deafened ear. In most reported cases, the unilateral deafness has been a profound sensorineural hearing loss with a sudden onset that has been variously attributed to bacterial or viral labyrinthitis, acoustic or cranial trauma, otosclerosis, and congenital CMV infection. Familial occurrence of the syndrome has not previously been reported in the literature. In this report, we describe two possible familial instances of delayed DEH. These patients ra...

British Library Electronic Table of Contents (United Kingdom)

TP63, a member of the TP53 gene family, is a nuclear marker of myoepithelial cells. Antibody against p63 is frequently used to aid in the diagnosis of prostate carcinoma, as well as in the identification of myoepithelial cells in other tissues including the breast. p63 is also a marker for squamous cell carcinoma. Recently, it was found that all p53 family members are involved in regulating the process of muscle differentiation through the retinoblastoma (RB) protein. Ablation of these p53 family functions blocks the differentiation program and promotes malignant transformation by enabling cooperating oncogenes to transform myoblasts. We therefore studied p63 expression in a number of neoplasms with myogenic differentiation. Immunohistochemical staining for p63 was performed on paraffin se...

Energy Technology Data Exchange (ETDEWEB)

Salt stress elicits betaine accumulation to high levels in species from several diverse dicot families (Chenopodiaceae, Amaranthaceae, Convolvulaceae, Solanaceae, and Asteraceae). FAM-MS studies with deuterated precursors showed that species from all these families synthesize betaine from choline. Enzyme assays and immunotitration data showed that all accumulating species contained betaine aldehyde dehydrogenase (BADH) enzyme activity recognized by antibodies raised against purified BADH isolated from Spinacia oleracea. Immunoblotting indicated that the BADH monomer was in all cases of Mr {approx} 63,000. The similarity of BADH in the different species is consistent with a single evolutionary origin for the betaine pathway. This was supported by the presence in immunoblots of a cross-reacting band at Mr {approx} 63,000 in Magnolia x Soulangiana, a primitive angiosperm.

British Library Electronic Table of Contents (United Kingdom)

Given the important role of parent-youth communication in adolescent well-being and quality of life, we sought to examine the relationship between specific communication variables and youth perceived quality of life in general and as a deaf or hard-of-hearing (DHH) individual. A convenience sample of 230 youth (mean age = 14.1, standard deviation = 2.2; 24% used sign only, 40% speech only, and 36% sign + speech) was surveyed on communication-related issues, generic and DHH-specific quality of life, and depression symptoms. Higher youth perception of their ability to understand parents' communication was significantly correlated with perceived quality of life as well as lower reported depressive symptoms and lower perceived stigma. Youth who use speech as their single mode of communication ...

British Library Electronic Table of Contents (United Kingdom)

Summary 1. A primary goal of evolutionary ecology is to understand factors selecting for the diversity of life histories. Life-history components, such as time-to-reproduction, adult survivorship and fecundity, might differ among species because of variation in direct and indirect benefits of these life histories in different environments or might have lower-than-expected variability because of phylogenetic constraints. Here, we present a phylogenetic examination of demography and life histories using a data base of 204 terrestrial plant species. 2. Overall, statistical models without phylogeny were preferred to models with phylogeny for vital rates and elasticities, suggesting that they lacked phylogenetic signal and are evolutionarily labile. However, the effect of phylogeny was signific...

Energy Technology Data Exchange (ETDEWEB)

In order to improve the well-known short operational life time of BF3 counters, three potential adsorbents for impurity gases (graphite, activated charcoal and a zirconium-aluminum mixture) were introduced into BF3 counters in the form of coating on the aluminum cathode surface. Tests in el fields revealed that a partial coating of activated charcoal provides the best result. The improvement of their operational life in el fields was about three orders of magnitude in terms of tolerable exposure. Many counters with a partial coating of activated charcoal were further tested from the following viewpoints: background noise, vibration and shock, el pulse discrimination, operational life in a neutron field and non-operational in-reactor exposure life. The results were satisfactory for reactor control and protection usage. (author).

UK PubMed Central (United Kingdom)

BackgroundHow socio-demographic factors influence women's autonomy in decision making on health care including purchasing goods and visiting family and relatives are very poorly...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundAntioxidant vitamins are often described as having “independent” associations with risk of cancer, cardiovascular disease (CVD) and mortality. We aimed...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundCongenital microcoria (CMC) is due to a maldevelopment of the dilator pupillae muscle of the iris, with a pupil diameter of less than 2 mm. It is associated with juvenile...Full Text Available

UK PubMed Central (United Kingdom)

OBJECTIVETo determine if ProL1, a member of the opiorphin family of genes, can modulate erectile physiology, as it encodes a peptide which acts as...Full Text Available

UK PubMed Central (United Kingdom)

An outbreak of acute respiratory disease in Hendra, a suburb of Brisbane, Australia, in September 1994 resulted in the deaths of 14 racing horses and a horse trainer. The causative agent was a new member...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundHepatitis B (HBV) and C (HCV) infections are a serious global and national public health problem. Earlier studies have reported increasing rates of hepatitis infection...Full Text Available

UK PubMed Central (United Kingdom)

SummaryTRPV1 is the founding and best-studied member of the family of temperature-activated transient receptor potential ion channels (thermoTRPs). Voltage, chemicals, and heat...Full Text Available

Science.gov (United States)

This book chapter discusses sugarcane culture and history, describes arthropod biologies and injury, and identifies sugarcane pest management factors to consider for people interested in commercial sugarcane production. Arthropod groups include 10 orders and 40 families. Sugarcane pest management ...

UK PubMed Central (United Kingdom)

Recognition of acetylated chromatin by the bromodomains and extra-terminal domain (BET) family proteins is a hallmark for transcriptional activation and anchoring viral genomes to mitotic chromosomes...Full Text Available

UK PubMed Central (United Kingdom)

Using longitudinal data from the Youth Development Study (analytic sample N = 712), we investigate how age, adult role acquisition and attainments, family resources, parent-child relationship...Full Text Available

UK PubMed Central (United Kingdom)

The etiology of major depression remains unknown, but dysfunction of serotonergic signaling has long been implicated in the pathophysiology of this disorder. p11 is an S100 family member recently...Full Text Available

Science.gov (United States)

Studies were assigned values based on whether they were anecdotal or ... or family income), work experience, birth order, military or civilian ...... observed with submarine personnel and polar expeditioners (Sandal et al., 1996). ...

UK PubMed Central (United Kingdom)

Human longevity is in part genetically determined, and the insulin/IGF-1 signal transduction (IIS) pathway has consistently been implicated. In humans, type 2 diabetes is a frequent disease that results...Full Text Available

UK PubMed Central (United Kingdom)

About 20% of adults are persistently colonized with S. aureus in the anterior nares. Host genetic factors could contribute susceptibility to this phenotype. The objective of...Full Text Available

UK PubMed Central (United Kingdom)

cdc18+ of Schizosaccharomyces pombe is a periodically expressed gene that is required for entry into S phase and for the coordination of S phase with mitosis. cdc18+ is related to the Saccharomyces...Full Text Available

UK PubMed Central (United Kingdom)

Antagonists for kainate receptors (KARs), a family of glutamate-gated ion channels, are efficacious in a number of animal models of neuropathologies, including epilepsy, migraine pain, and anxiety....Full Text Available

UK PubMed Central (United Kingdom)

The ToxRS system in Vibrio cholerae plays a central role in the modulation of virulence gene expression in response to environmental stimuli. An integration of multiple signalling inputs...Full Text Available

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Sirt1 (member of the sirtuin family) is a nicotinamide adenosine dinucleotide (NAD)-dependent deacetylase that removes acetyl groups from various proteins. Sirt1 performs a wide variety of functions...Full Text Available

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Reversion-induced LIM protein (RIL) is a member of the ALP (actinin-associated LIM protein) subfamily of the PDZ/LIM protein family. RIL serves as an adaptor protein and seems to regulate cytoskeletons....Full Text Available

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BackgroundSerine proteinase inhibitors (Serpins) are a large superfamily of structurally related, but functionally diverse proteins that control essential proteolytic pathways in...Full Text Available

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Juvenile hormone analog (JHA) insecticides are relatively nontoxic to vertebrates and offer effective control of certain insect pests. Recent reports of resistance in whiteflies and mosquitoes demonstrate...Full Text Available

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... Hospital & University Hospital Basel) If I Had - Pre-diabetes - Dr. Venkat Narayan, MD, MSc, MBA, Rollins School ... School, Massachusetts General Hospital, Discusses the Treatment of Diabetes Back to Home Page If I Had - A ...

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The Moloney murine leukemia virus (MMLV) belongs to the Retroviridae family of enveloped viruses, which is known to acquire minute amounts of host cellular proteins both on the surface...Full Text Available

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Heat shock proteins (Hsp) are a family of stress-inducible molecular chaperones that play multiple roles in a wide variety of animals. However, the roles of Hsps in parasitic nematodes remain largely...Full Text Available

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BackgroundCucumis melo (melon) belongs to the Cucurbitaceae family, whose economic importance among horticulture crops is second only to Solanaceae. Melon has high...Full Text Available

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Inactivation of the RB tumor suppressor and activation of the MYC family of oncogenes are frequent events in a large spectrum of human cancers. Loss of RB function and MYC activation are thought to...Full Text Available

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Premature menopause, ovarian failure younger than 40 years of age, is relatively rare but may preclude childbearing for some women who delay attempts at fertility. We present five kindreds in which...Full Text Available

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BackgroundLeukotrienes (LTs) belong to the large family of lipid mediators implicated in various inflammatory conditions such as asthma and rheumatoid arthritis. Four distinct types...Full Text Available

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PknB is a member of the newly discovered eukaryotic-like protein serine/threonine kinase (PSTK) family of proteins. The pknB gene was cloned and expressed in Escherichia coli....Full Text Available

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Forty-one Spanish families with polycystic kidney disease 1 (PKD1) were studied for evidence of linkage disequilibrium between the disease locus and six closely linked markers. Four of these loci--three...Full Text Available

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Neurofibromatosis type 1 (NF-1) and tuberous sclerosis complex (TSC) are two familial syndromes known as phakomatoses that may be associated with endocrine tumors. These hereditary cutaneous...Full Text Available

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Bistability plays a central role in the gene regulatory networks (GRNs) controlling many essential biological functions, including cellular differentiation and cell cycle control. However, establishing...Full Text Available

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FXYD1 (phospholemman) is a member of an evolutionarily conserved family of membrane proteins that regulate the function of the Na,K-ATPase enzyme complex in specific tissues and specific physiological...Full Text Available

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Small RAC/ROP-family G proteins regulate development and stress responses in plants. Transient overexpression and RNA interference experiments suggested that the barley (Hordeum vulgare)...Full Text Available

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The p21-activated kinases (PAKs), immediate downstream effectors of the small G-proteins of the Rac/cdc42 family, are critical mediators of signaling pathways regulating cellular behaviors and...Full Text Available

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Post amputation pain can be debilitating for patients and families. Chronic pain is a common phenomenon after lower extremity amputation, occurring in up to 80% of this population. The purpose of this...Full Text Available

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BackgroundComplex situations that follow war and natural disasters have a psychosocial impact on not only the individual but also on the family, community and society. Just as the...Full Text Available

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BackgroundThe rate of emergence of human pathogens is steadily increasing; most of these novel agents originate in wildlife. Bats, remarkably, are the natural reservoirs of many...Full Text Available