Energy Technology Data Exchange (ETDEWEB)

Pregraduate medical curricula are currently undergoing a reform process that is moving away from a traditional discipline-related structure and towards problem-based integrated forms of teaching. Imaging sciences, with their inherently technical advances, are specifically influenced by the effects of paradigm shifts in medical education. The teaching of diagnostic radiology should be based on the definition of three core competencies: in vivo visualization of normal and abnormal morphology and function, diagnostic reasoning, and interventional treatment. On the basis of these goals, adequate teaching methods and e-learning tools should be implemented by focusing on case-based teaching. Teaching materials used in the fields of normal anatomy, pathology, and clinical diagnosis may help diagnostic radiology to play a central role in modern pregraduate curricula. (orig.)

UK PubMed Central (United Kingdom)

Objective To determine whether a centralised telephone intervention reduces the incidence of death or admission for worsening heart failure in outpatients with chronic heart failure.Design...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

The objectives of this paper are to: quickly outline the extent of the care gap in osteoporosis; define T-2 (knowledge) translation and its relationship to quality improvement; discuss the barriers to best practice in osteoporosis care after a fracture; convey the importance of rigor in design and evaluation of translational interventions by drawing upon examples from the broader literature; describe in some detail a series of post-fracture intervention trials conducted in Alberta, Canada; and make some conclusions specifically about osteoporosis interventions and more generally about T-2 translational research.

UK PubMed Central (United Kingdom)

BackgroundThe evaluation of interventions and policies designed to promote resilience, and research to understand the determinants and associations, require reliable and valid measures...Full Text Available

UK PubMed Central (United Kingdom)

ObjectiveTo test whether a disclosure intervention improves subjective health and reduces medical consumption and sick leave in somatising patients in general practice.DesignNon-blind...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundHip fracture patients often have an impaired nutritional status at the time of fracture, which can result in a higher complication rate, prolonged rehabilitation time and...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundWith rates of childhood obesity increasing, physical activity (PA) promotion especially in young children has assumed greater importance. Given the limited effectiveness...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Aim: To systematically review the currently available high quality evidence evaluating treatments for moist desquamation in radiotherapy patients. Design: Systematic literature review. Methods: Electronic databases, websites, reference lists, key journals and conference proceedings were searched. Attempts were also made to uncover unpublished material. Relevant studies proceeded to data extraction and quality assessment. Results: Twenty studies were found; 10 were eligible for inclusion. Although many studies were small, none had unacceptably poor quality. No meta-analysis was undertaken as the studies were not homogenous in their interventions or methods. No convincing evidence for any intervention was found. Conclusion: Despite being recommended by many guidelines (College of Radiographers Summary of Intervention for Acute Radiotherapy Induced Skin Reactions in Cancer Patients (London, 2001); NHS ...

British Library Electronic Table of Contents (United Kingdom)

Deltombe T, Gustin T. Selective tibial neurotomy in the treatment of spastic equinovarus foot in hemiplegic patients: a 2-year longitudinal follow-up of 30 cases. Objective To assess the long-term efficacy of selective tibial neurotomy in the treatment of spastic equinovarus foot in hemiplegic patients. Design Intervention study (before-after trial) with an observational design and 2-year follow-up. Setting Spasticity group in a university hospital. Participants Hemiplegic patients (N=30) with spastic equinovarus foot. Intervention A selective neurotomy was performed at the level of the motor nerve branches of the tibial nerve. Main Outcome Measures Spasticity (Ashworth scale), muscle strength (Medical Research Council scale), passive ankle dorsiflexion, gait parameters (6 min walking test...

DEFF Research Database (Denmark)

Epidemiological studies of psychopathology in the first years of life are few, and the association between mental health problems in infancy and psychiatric disturbances later in life has not been systematically investigated. The aim of the present project was to study mental health problems and possibilities of intervention from infancy and onward.

British Library Electronic Table of Contents (United Kingdom)

ABSTRACT Aim The study aimed to test simultaneously our understanding of the effects of bupropion sustained-release (SR) treatment on putative mediators and our understanding of determinants of post-quit abstinence, including withdrawal distress, cigarette craving, positive affect and subjective reactions to cigarettes smoked during a lapse. The specificity of bupropion SR effects was also tested in exploratory analyses. Design Data from a randomized, placebo-controlled clinical trial of bupropion SR were submitted to mediation analyses. Setting Center for Tobacco Research and Intervention, Madison, WI, USA. Participants A total of 403 adult, daily smokers without contraindications to bupropion SR use. Intervention Participants were assigned randomly to receive a 9-week course of bupropion...

British Library Electronic Table of Contents (United Kingdom)

Despite advances in polymer and drug technology, the underlying stent platform remains a key determinant of clinical outcome. A clear understanding of stent design and the differences between various stent platforms are of increasing importance for the interventional cardiologist. Reduction in stent strut thickness has been associated with improved stent deliverability, improved procedural outcome, and lower rates of subsequent restenosis. Newer-generation 316L-SS stent designs have enabled reduced strut thickness while retaining radial strength and minimizing recoil, but with significant loss of radiopacity, leading to reduced visibility. Cobalt chromium alloys have enabled a reduction in stent strut thickness to around 80?90 mm while retaining modest radiopacity, but due to higher elasti...

UK PubMed Central (United Kingdom)

Conducting rigorous psychosocial intervention research with cancer patients has many challenges including encouraging them to join studies, asking them to engage in interventions or be part...Full Text Available

UK PubMed Central (United Kingdom)

AbstractObjective: This study examined the effectiveness of a telephone-based referral-care management (TBR-CM) intervention on psychiatric health...Full Text Available

Science.gov (United States)

BackgroundNatural disasters result in significant numbers of disabling impairments. Paradoxically, however, the traditional health system response to natural disasters largely neglects health-related rehabilitation as a strategic intervention.ObjectivesTo examine the role of health-related rehabilitation in natural disaster relief along three lines of inquiry: (1) epidemiology of injury and disability, (2) impact on health and rehabilitation systems, and (3) the assessment and measurement of disability.DesignQualitative literature review and secondary data analysis.ResultsAbsolute numbers of injuries as well as injury to death ratios in natural disasters have increased significantly over the last 40 years. Major impairments requiring health-related rehabilitation include amputations, traumatic brain injuries, spinal cord injuries (SCI), and long bone fractures. Studies show that persons with pre-existing disabilities are more likely to die in a ...

International Nuclear Information System (INIS)

There are two major distinct activities involved with reprocessing of nuclear fuel. They are: a) Mechanical handling of the fuel in the head end plants; and b) chemical dissolution and separation of unused fuel, useful by-products and waste products. Plants and facilities associated with the former include significant remote handling equipment that is designed for handling of fuel for normal production processes. These equipment are selected and designed to meet the design throughput of the plant taking into consideration ease of their operation and maintenance in conjunction with statutory regulations on safety and operator dose uptake. Nevertheless, during the life of the plant, there are instances when special equipment is called for to access part of the plant and undertake tasks such as inspection, maintenance and modification to improve the existing process. BNFL has much experience in the design ...

Science.gov (United States)

PMID:19208697

British Library Electronic Table of Contents (United Kingdom)

Aim.- To identify what determinants influence the prevalence and accuracy of nursing diagnosis documentation in clinical practice. Background.- Nursing diagnoses guide and direct nursing care. They are the foundation for goal setting and provide the basis for interventions. The literature mentions several factors that influences nurses- documentation of diagnoses, such as a nurse-s level of education, patient-s condition and the ward environment. Design.- Systematic review. Method.- MEDLINE and CINAHL databases were searched using the following headings and keywords: nursing diagnosis, nursing documentation, hospitals, influence, utilisation, quality, implementation and accuracy. The search was limited to articles published between 1995-October 2009. Studies were only selected if they were...

Science.gov (United States)

Two third-grade Taiwanese students at risk for emotional and behavioral disorders participated in a pull-out, small-group social skills training program developed to promote their skill acquisition and maintenance. Using a multiple baseline across skills design, the authors demonstrated that both participants made marked performance improvement in all three targeted social skills of on-task, appropriate conflict resolution, and cooperation during the intervention condition. Maintenance and follow-up data showed that both participants sustained their use of taught social skills in the training setting and their third-grade classroom, respectively. Social validity measures, including peer sociometric ratings and consumer satisfaction questionnaires and interviews, supported the positive effects of the social skills training program for both participants. Implications for research and practice are discussed. (Contains 2 tables and 2 figures.)

British Library Electronic Table of Contents (United Kingdom)

Background: Quantifying HIV levels in mucosal secretions is essential to study compartmentalized expression of HIV and facilitate development of intervention strategies to prevent disease progression and transmission. Objectives: To develop a sensitive, reliable, and cost-effective technique to quantify HIV from blood and vaginal secretions that is compatible with efficient implementation in clinical research environments. Study design: A sensitive, reliable, internally-controlled real-time reverse transcriptase (RT) PCR assay, which uses the HIV-1 pol gene as a target (Hpol assay) was developed to quantify HIV levels in plasma and genital secretions, and compared to the widely used Roche Amplicor(TM) HIV-1 Monitor assay. In addition, a simplified method of sample collection and processing...

Energy Technology Data Exchange (ETDEWEB)

An adaptive power system stabilizer (APSS) employing a new self-optimizing pole shifting control strategy and its application to a power system are described in this paper. Based on an identified model of the system, the control is computed by an algorithm which shifts the closed-loop poles of the system to some optimal locations inside the unit circle in the z-domain to minimize a given performance criterion. With the self-optimization property, outside intervention in the controller design procedure is minimized, thus simplifying the tuning procedure during commissioning. Also, a new method of calculating the variable forgetting factor in real-time parameter identification is discussed. Studies show that the proposed APSS can provide good damping of the power system over a wide operating range and significantly improve the dynamic performance of the system.

Energy Technology Data Exchange (ETDEWEB)

Analyses have been performed of the potential consequences to the public of hypothetical loss-of-coolant accidents in conceptual fusion power plant designs. In order to establish upper bounds to the consequences of such events, a case has been studied in which total loss of all active cooling has been assumed, with no remedial intervention for the duration of the accident sequence. The analyses are based on three conceptual power plant designs, two of them similar to those assumed in the earlier safety and environmental assessment of fusion power (SEAFP) study (Raeder et al., 1995), with updating of assumed structural materials. The three models studied provide a broad range of design options. In all cases the decay-heat driven temperature transients are well below the level at which structural melting would begin. Based on conservative assumptions, mobilisation, release and dose calculations show that ...

CERN Document Server

IP Multicast is one of the most absolute method for large bandwidth Internet applications such as video conference, IPTV, E-Learning and Telemedicine etc., But due to security and management reason IP Multicast is not enabled in Internet backbone routers. To achieve these challenges, lot of Application Layer Multicast (ALM) has been proposed. All the existing protocols such as NICE, ZIGZAG and OMNI are trying to reduce average delay by forming a Multicast tree. But still that problem has not been addressed fully. We are proposing a new protocol called NetRawALM, which will address the average delay, Reliability between nodes, Scalability of conference, Heterogeneity and resilient data distribution for real time multimedia applications by constructing the Network based Resource aware Multicast tree algorithm. This is very dynamic and decentralised. The proposed architecture is a LAN aware; it is used to reduce Internet Traffic.

UK PubMed Central (United Kingdom)

ObjectivesThe aim of this study was to assess the diagnostic and prognostic value of heart-type fatty acid-binding protein (H-FABP) in elective percutaneous coronary intervention...Full Text Available

UK PubMed Central (United Kingdom)

ObjectiveTo evaluate a faith-based intervention (“Sisters in Motion”) intended to increase walking among older, sedentary African American women.Full Text Available

UK PubMed Central (United Kingdom)

Peripheral vascular diseases (PVD) are referred to as diseases affecting the blood vessels other than the heart and the brain. Interventional endovascular treatment whenever feasible has become the...Full Text Available

UK PubMed Central (United Kingdom)

Outpatient practice after percutaneous coronary intervention (PCI) is gaining momentum due to constantly optimizing results. Furthermore, the availability of limited beds to handle the large volume...Full Text Available

UK PubMed Central (United Kingdom)

Given the high prevalence of overweight and low levels of physical activity among children, a better understanding of physical activity behaviour is an important step in intervention planning. This...Full Text Available

UK PubMed Central (United Kingdom)

Despite an accumulating body of literature addressing racial/ethnic disparities in children’s health and health care, there have been few published studies of interventions that have...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe effects of intervention programs on health-related quality of life (HRQOL) of patients with hip fracture have not been well studied. We hypothesized that older patients...Full Text Available

UK PubMed Central (United Kingdom)

ObjectiveThe objective of this study was to determine the contribution of distance to hospitals with cardiac interventional services (CIS) to county age-adjusted myocardial infarction...Full Text Available

UK PubMed Central (United Kingdom)

ObjectiveThere has been much debate about the value of condoms in HIV/STI programming. This should be informed by evidence about intervention impact on condom use, but there is limited...Full Text Available

UK PubMed Central (United Kingdom)

This prospective controlled intervention study over 12 months evaluated the effect of exercise on muscular function, physical ability, and body composition in pre-pubertal boys. Sixty-eight boys aged...Full Text Available

Science.gov (United States)

... in the processes of production and, partic- ularly, product distribution and also by the increase in directive and disciplinary methods of intervention ...

International Nuclear Information System (INIS)

The clinical feasibility of using interventional examination techniques was tested with an equipment combining fluoroscopy and MR imaging. This hybrid system showed to be of advantage in a great number of interventional examinations. The 1.5 Tesla magnet proved to be superior to open MR scanning systems in terms of image quality and scanning times. (orig.).

International Nuclear Information System (INIS)

Since the publication by the International Commission on Radiological Protection of revised recommendations which set out some general principles for intervention, some ideas have emerged which address interventions in the case of chronic exposure from contaminated lands. In the past there have been interventions proposed or carried out to rehabilitate land contaminated during the era of atmospheric nuclear weapon testing. Some of these interventions are reviewed in the context of these ideas and it is concluded that, by and large, reasonable outcomes have been achieved. The concept of a 'generic action level' (an effective dose of the order of 10 mSv#centre dot#a"-"1 to representative individuals in the critical group) may be useful in future to aid decision makers in determining whether intervention is appropriate. (author)

Energy Technology Data Exchange (ETDEWEB)

In the discussion of environmental architecture, we are conjoining two disciplines, the subject of architecture and that of ecology. At their best, green buildings are examples of applied ecology, where designers understand the constitution, organization, and structure of ecosystems, and the impacts of architecture are considered from an environmental perspective. By utilizing the concepts, methods, and language of ecology, designers can create architecture that intentionally engages the natural systems of a site. The establishment of assessment criteria implies the definition of building design criteria. If we establish criteria that are based on our best scientific understanding of environmental capacity, we will begin to develop a building stock that is sustainable. To do this we must quantify the link between the resulting environmental impacts and their cause in building production and use. This is not done in ...

UK PubMed Central (United Kingdom)

BackgroundElementary schools represent both a source of childhood sun exposure and a setting for educational interventions.MethodsSun Protection...Full Text Available

UK PubMed Central (United Kingdom)

ObjectiveAngiography remains a critical component for diagnostic imaging and therapeutic intervention in peripheral arterial disease (PAD). The goal of this study...Full Text Available

UK PubMed Central (United Kingdom)

Governments are increasingly concerned to compare the quality and effectiveness of healthcare interventions but find this a complex matter. Crude hospital statistics can be dangerously misleading and...Full Text Available

Science.gov (United States)

Finite element methods have been applied extensively and with much success in the analysis of orthopaedic implants. Recently a growing interest has developed, in the orthopaedic biomechanics community, in how numerical models can be constructed for the optimal solution of problems in contact mechanics. New developments in this area are of paramount importance in the design of improved implants for orthopaedic surgery. Finite element and other computational techniques are widely applied in the analysis and design of hip and knee implants, with additional joints (ankle, shoulder, wrist) attracting increased attention. The objective of this investigation was to develop a simplified adaptive meshing scheme to facilitate the finite element analysis of a dual-curvature total wrist implant. Using currently available software, the analyst has great flexibility in mesh generation, but must prescribe element sizes and refinement schemes throughout the ...

UK PubMed Central (United Kingdom)

ObjectiveWe wanted to assess the usefulness of four-dimensional (4D) ultrasonography (US), i.e., real-time three-dimensional US, as an adjunct for performing various US-guided interventional...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

This paper assesses the effects of including carbon dioxide capture and storage (CCS) damage costs in a long-term energy scenario analysis for Europe. An external cost sensitivity analysis is performed with a bottom-up energy technology model that accounts not only for CCS technologies but also for their external costs. Our main conclusion is that in a business-as-usual scenario (i.e. without climate change intervention or externality internalisation), CCS technologies are likely to be deployed at least to some extent, mainly in the power generation sector, given the economic benefits of opportunities such as enhanced coal bed methane, oil and gas recovery. Under a strict climate (CO{sub 2} emissions) constraint, CCS technologies are deployed massively. With the simultaneous introduction of both CO{sub 2} and CCS taxation in the power sector, designed to internalise the external atmospheric and geological effects of CO{sub 2} emissions and ...

Energy Technology Data Exchange (ETDEWEB)

The clinical feasibility of using interventional examination techniques was tested with an equipment combining fluoroscopy and MR imaging. This hybrid system showed to be of advantage in a great number of interventional examinations. The 1.5 Tesla magnet proved to be superior to open MR scanning systems in terms of image quality and scanning times. (orig.) [Deutsch] Es wurde die klinische Durchfuehrbarkeit interventioneller Techniken an einem kombinierten Durchleuchtungs- und MR-Arbeitsplatz untersucht. Dieses Hybridsystem erwies sich bei einer Vielzahl interventioneller Eingriffe als vorteilhaft. Der 1,5 Tesla-Magnet ist offenen MR-Systemen hinsichtlich Bildqualitaet und Messzeit ueberlegen. (orig.)

Science.gov (United States)

... Amount Background Radiation Blood vessel central line, PICC (peripherally inserted central catheter) or port placement, simple 0.4 mSv ...

UK PubMed Central (United Kingdom)

BackgroundThe use of measurement tools is an essential part of good evidence-based practice; however, physiotherapists (PTs) are not always confident when selecting, administering,...Full Text Available

UK PubMed Central (United Kingdom)

Shoulder pain is a common orthopedic condition seen by physical therapists, with many potential contributing factors and proposed treatments. Although manual physical therapy interventions for the cervicothoracic...Full Text Available

UK PubMed Central (United Kingdom)

Malaria parasites must undergo a round of sexual reproduction in the blood meal of a mosquito vector to be transmitted between hosts. Developing a transmission-blocking intervention to prevent parasites...Full Text Available

UK PubMed Central (United Kingdom)

Globally, sexually transmitted infections (STIs) represent a significant source of morbidity and disproportionately impact the health of women and children. The number of randomized controlled trials...Full Text Available

UK PubMed Central (United Kingdom)

While most cancer survivors are at risk for being lost in the transition from treatment to survivorship, rural breast cancer survivors face special challenges that might place them at particular...Full Text Available

UK PubMed Central (United Kingdom)

Cognitive rehabilitation is an effective intervention for addressing cognitive impairments in patients with schizophrenia. Previous research has shown that the early application of Cognitive...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundPhysicians have difficulty keeping up with new evidence from medical research.MethodsWe developed the McMaster Premium...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundHigh serum uric acid concentration (hyperuricemia) has been studied for its relationship with multiple adverse health outcomes, such as metabolic syndrome. Intervention...Full Text Available

UK PubMed Central (United Kingdom)

Tracheobronchial balloon dilation and stent placement have been well used in the treatment of patients with benign and/or malignant diseases. Balloon dilation is the first option in the treatment of...Full Text Available

UK PubMed Central (United Kingdom)

IntroductionIn lung cancer surgery, large tidal volume and elevated inspiratory pressure are known risk factors of acute lung (ALI). Mechanical ventilation with low tidal volume...Full Text Available

Science.gov (United States)

This study was performed to assess the possibility that patient age may independently affect improvements in health-related quality of life following percutaneous coronary intervention. One hundred five patients undergoing elective percutaneous coronary intervention at a single tertiary referral center between January 10, 2001 and January 6, 2002 were enrolled and prospectively evaluated. Health-related quality of life was assessed before and 1 year following percutaneous coronary intervention using Short Form-12 and the Seattle Angina Questionnaire. For the purpose of analysis, patients were divided according to age (younger than 60, 60-70, and older than 70 years). One hundred patients (95%) completed both questionnaires. Baseline characteristics among the age groups were similar in terms of gender, cardiac risk factors, and procedural details. All health-related quality-of-life indices demonstrated improvements with at ...

UK PubMed Central (United Kingdom)

Giant lipomas are benign soft tissue tumours. They are found relatively rarely on the posterior part of the neck. Bleeding pressure ulcer in this giant tumour is a rare presentation. Surgical interventions...Full Text Available

UK PubMed Central (United Kingdom)

The effects of 2 forms of response interruption and redirection (RIRD)—motor RIRD and vocal RIRD—were examined with 4 boys with autism to evaluate further the effects of this intervention...Full Text Available

UK PubMed Central (United Kingdom)

Background:This study evaluated the outcomes of patients with complex or persistent thoracobiliary fistulae following penetrating liver trauma, who underwent endoscopic biliary intervention...Full Text Available

UK PubMed Central (United Kingdom)

In response to reports that the contamination of food can occur during the on-farm primary phase of food production, we report data that describes a possible cost-effective intervention measure. The...Full Text Available

UK PubMed Central (United Kingdom)

A paradoxical metabolic imbalance in inorganic phosphate occurs from the early onset of diabetes and may lead to a reduction of high energy phosphates and tissue hypoxia. These changes take place in...Full Text Available

UK PubMed Central (United Kingdom)

The ethical dimension of treating the elderly, including risk–benefit analysis, focuses mainly on quality of life and end-of-life issues. These include arguments on advance directives and the...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundInadequate platelet inhibition despite aspirin and clopidogrel therapy during and after a percutaneous coronary intervention is associated with an impaired clinical outcome....Full Text Available

UK PubMed Central (United Kingdom)

Most physicians dealing with Jehovah's Witnesses (JWs) who refuse blood-based treatment are uncertain as to any obligation to educate patients where it concerns the JW blood doctrine itself. They often...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundQuantitative sensory testing (QST) is applied to evaluate somatosensory nerve fiber function in the spinal system. This study uses QST in patients with sensory dysfunctions...Full Text Available

UK PubMed Central (United Kingdom)

We report an unusual case of strangulated diaphragmatic (Morgagni) hernia resulting in ischaemia of the small and large bowel, which was initially diagnosed as a pneumonia. This case highlights the...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundImproving nutrition knowledge among children may help them to make healthier food choices. The aim of this study was to assess the effectiveness and acceptability of a...Full Text Available

UK PubMed Central (United Kingdom)

There are a range of barriers precluding patients from fully engaging in and benefiting from the spectrum of eHealth interventions developed to support patient access to health information, disease...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Background The American Association for the Study of Liver Diseases (AASLD) guidelines recommend that antibiotic prophylaxis should be instituted in any patient with cirrhosis and gastrointestinal hemorrhage, and that oral norfloxacin, intravenous ciprofloxacin, and ceftriaxone are preferable. However, the antimicrobial spectrum of the first generation of cephalosporins (cefazolin) covers a wide range of bacteria species, including community-acquired strains of Escherichia coli and Klebsiella pneumoniae, but their efficacy as prophylactic antibiotics in cirrhotic patients with acute hemorrhage was seldom warranted in the literature. This study aimed to explore the effects of cefazolin on the outcome of cirrhotic patients with acute variceal hemorrhage after endoscopic interventions. Method...

Science.gov (United States)

This article reviews antisocial personality disorder, psychopathy, and violence and develops a three factor model of personality traits. Then a discussion of related personality disorders precedes the development of a categorical two factor model of impulsive versus remorseless violence. A paradigm of proactive, medical, and school based early intervention and prevention is advocated as a useful addition to the reactive detention of criminal justice. Integration of psychological tests, neuroimaging, and genomic data in early childhood and school based intervention strategies to prevent the development of conduct disorder and attenuate criminal propensity inform this approach. PMID:20422651

British Library Electronic Table of Contents (United Kingdom)

Phelps N. A. Cluster or capture? Manufacturing foreign direct investment, external economies and agglomeration, Regional Studies.?This paper reviews the nature and significance of external economies associated with multinational enterprise (MNE) participation in the manufacturing industries of host economies. It argues that the balance of forces of internalization and externalization is currently skewed towards the former and the interests of MNEs rather than the latter and the interests of local and national communities and governments. A stylized comparison of developmental and competition state interventions in relation to MNEs and their foreign direct investment (FDI) suggests that in the absence of co-ordinated interventions by governments, there will commonly be a failure of t...

CERN Document Server

The subject of the 5th challenge proposed by the French Society of Operations Research and Decision Analysis (ROADEF) consists in scheduling technicians and interventions for telecommunications (http://www.g-scop.inpg.fr/ChallengeROADEF2007/ or http://www.roadef.org/). We detail the algorithm we proposed for this challenge which is a Greedy Randomized Adaptative Search Procedure (GRASP). Computational results led us to the 1st position in the Junior category and to the 4th position in All category of the Challenge ROADEF 2007.

DEFF Research Database (Denmark)

The background for this paper is a growing interest during the past decade in Denmark in the concepts of ?situated learning?, ?social theory of learning? and ?learning in communities of practice? developed by the American social anthropologist Jean Lave and the Californian Research Scientist Etienne Wenger. The work by Jean Lave from 1988 (Lave, 1988) based on anthropological field studies in Brazil and Liberia as well as later works by Lave & Wenger (Lave and Wenger, 1991; Chaiklin and Lave, 1993; Wenger, 1998; Wenger, McDermott, R. and W. Snyder, 2002) on situated learning and social learning theory have provoked considerable response in anthropological studies, in learning theories as well asin considerations about practical implementation of concepts like ?lifelong learning? in Denmark in recent decades. The European concept of ?lifelong learning? has had a big impact on educational thinking, including teacher education. In addition to this, IT has been playing a continuously ...

CERN Document Server

Statistical Analysis of Designed Experiments

Indian Academy of Sciences (India)

designed to work with companion standards ...

British Library Electronic Table of Contents (United Kingdom)

Abstract An increase in chronic disease prevalence is contributing to health care cost growth and decreased quality of life in industrialized nations worldwide. Inadequate management of chronic diseases is a leading cause of hospitalizations and, thus, avoidable expenditures. In this study, we evaluated the impact of nurse-delivered care calls, the primary intervention of a proactive chronic care management (CCM) program, in a population aged 65 and older in Germany. In this analysis, hospital admission rates were evaluated among program enrollees who were diagnosed with diabetes, heart failure, coronary heart disease, or chronic obstructive pulmonary disease. The Intervention group comprised those members who participated in care calls (n?=?13,486), whereas the Comparison group included e...

British Library Electronic Table of Contents (United Kingdom)

Researchers have identified as effective and worthy of broader dissemination a variety of intervention strategies to promote physical activity among older adults. This paper reports results of a community-organizing approach to disseminating evidence-based interventions in a sustainable way: The Southeast Seattle Senior Physical Activity Network (SESPAN). SESPAN was implemented in Southeast Seattle, a group of multicultural neighborhoods extending 8?miles southeast of downtown Seattle, with a population of 56,469 in 2000, with 12% (7,041) aged 65 and older. The SESPAN organizing strategy involved networking to: (1) make connections between two or more community organizations to create new senior physical activity programs; and (2) build coalitions of community groups and organizations to a...

British Library Electronic Table of Contents (United Kingdom)

Long-term fishery datasets can provide valuable insights into fishing histories, and represent a baseline against which to examine current status and plan for future management. For coral reef-associated fisheries, however, such datasets are extremely rare. We analyse a unique 45-year set of landings data on six reef fishes of commercial importance in Cubas coastal fisheries, together with information on management interventions, and examine the likely implications of over-fishing and management on the long-term condition of one grouper (Serranidae) and five snapper (Lutjanidae) species. The data clearly demonstrate differential responses to fishing and management according to the biology of the different species examined. In particular, those species that aggregate most predictably, and a...

British Library Electronic Table of Contents (United Kingdom)

Evidence for dietary/nutritional treatments of attention-deficit/hyperactivity disorder (ADHD) varies widely, from double-blind, placebo-controlled trials to anecdotal. In guiding patients, clinicians can apply the SECS versus RUDE rule: treatments that are Safe, Easy, Cheap, and Sensible (SECS) require less evidence than those that are Risky, Unrealistic, Difficult, or Expensive (RUDE). Two nutritional treatments appear worth general consideration: Recommended Daily Allowance/Reference Daily Intake multivitamin/mineral supplements as a pediatric health intervention not specific to ADHD and essential fatty acids, especially a mix of eicosapentaenoic acid, docosahexaenoic acid, and ?-linolenic acid as an ADHD-specific intervention. Controlled studies support the elimination of artificial fo...

UK PubMed Central (United Kingdom)

ObjectivesA national survey in 1997 demonstrated that trachoma was endemic in Mali. Interventions to control trachoma including mass drug administration (MDA) with azithromycin were...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Ventricular septal defect after acute myocardial infarction (AMI) is a complication associated with poor outcome in the absence of intervention. We report a case of successful TEE guided transcatheter closure of a post myocardial infarction (MI) ventricular septal defect (VSD) with an Amplatzer occluder in a 79 years old male with cardiogenic shock.

International Nuclear Information System (INIS)

An Ottawa-based company, ECS-Power Systems Inc., has successfully completed a series of tests on an innovative device called a hydrodynamic port (HDP), which makes it possible to automatically initiate and maintain emergency cooling of a nuclear reactor core by natural processes, without relying in any way on human intervention, instrumentation, electric power, valves or moving parts of any kind.

Energy Technology Data Exchange (ETDEWEB)

Norad commissioned Econ Poeyry to map teaching and research activities and capacity related to clean energy in selected Ethiopian universities. The mapping identified challenges and opportunities with the aim of facilitating future intervention by the Ethiopian Government and donors to help improve the energy sector development of the country. The report covered the government-owned universities of Bahir Dar, Mekelle, Jimma, Arba Minch and Addis Ababa. The mapping was based on a questionnaire and on interviews at each university. (Author)

UK PubMed Central (United Kingdom)

BackgroundIntermittent preventive treatment of malaria during pregnancy (IPTp) is a key intervention in the national strategy for malaria control in Tanzania. SP, the current drug...Full Text Available

UK PubMed Central (United Kingdom)

Background:Methamphetamine is a major contributor to HIV transmission among men who have sex with men (MSM). Recent studies show that up to one-third of methamphetamine-using MSM...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

A reciprocal relationship informing both research and practice is one of the primary goals in the emerging field of Mind, Brain, and Education (MBE), yet the field has little documentation and analysis of such collaborations. In this article, we present case studies of three research-practice partnerships taking place between scientists and educators. By comparing and contrasting these three partnerships we expect to illuminate common characteristics, challenges, and benefits that come with doing MBE work.

International Nuclear Information System (INIS)

Full text: During JET operations, tritium contaminated waste is generated principally but not exclusively from 'intervention' work and from removing or replacing redundant items. It is essential for JET and for any future fusion plant to have available a route for managing each waste stream however large or small, both during operation and decommissioning of the plant. The long term outcome is to have for each tritiated waste stream from JET a route for its management leading to its eventual disposal or recycling (and thus to be available for similar waste streams which will be produced by ITER operations). Since several years SCK#centre dot#CEN has been developing techniques for the treatment of tritiated waste. Amongst them, technologies for water detritiation, for the treatment of tritiated organic liquids and for the decontamination of several types of solid tritiated waste. Our R and D focuses on the development of a system to decontaminate surface ...

CERN Document Server

A conceptual design for the module design and disc support structure for the ATLAS forward SCT tracker

International Nuclear Information System (INIS)

Objective: To explore the interventional treatment for biliary re-stenosis after metallic stents placement in patients due to cholangiocarcinoma and evaluate its therapeutic effect. Methods: Percutaneous metallic stents placement or combined with continuously infusion arterial chemotherapeutic and chemotherapeutic embolization were performed in 12 patients with biliary re-stenosis using 12 metallic stents. Results: Once stent placement was 100% successful in all 12 cases, TBIL, ALT, GTP and AKP values 7 days postoperatively were significantly lower than that in preoperation. Jaundice was reduced satisfactorily in 12 patients. 3 patients were undergone continuously arterial chemotherapeutics infusion and chemotherapeutic embolization 4 weeks after stents placement. Conclusions: Percutaneous replacement of biliary metallic stents was effective and safe for palliation of malignant biliary re-stenosis and would be much better when combined with continuously arterial ...

International Nuclear Information System (INIS)

Acute pneumothorax is a frequent complication after percutaneous pulmonary radiofrequency (RF) ablation. In this study we present three cases showing delayed development of pneumothorax after pulmonary RF ablation in 34 patients. Our purpose is to draw attention to this delayed complication and to propose a possible approach to avoid this major complication. These three cases occurred subsequent to 44 CT-guided pulmonary RF ablation procedures (6.8%) using either internally cooled or multitined expandable RF electrodes. In two patients, the pneumothorax, being initially absent at the end of the intervention, developed without symptoms. One of these patients required chest drain placement 32 h after RF ablation, and in the second patient therapy remained conservative. In the third patient, a slight pneumothorax at the end of the intervention gradually increased and led into tension pneumothorax 5 days after ablation procedure. Underlying ...

Energy Technology Data Exchange (ETDEWEB)

The onshore Potiguar basin has nowadays around 5.000 artificial lifting petroleum wells, distributed into 80 fields located on the states of Rio Grande do Norte and Ceara, representing approximately 8% of the national oil production. For that, well maintenance service, realized by Workover Rigs, is essential to preserve the oil productivity of the reservoirs on these fields. However, as the number of rigs is lower than to the number of wells needing maintenance, the task of administrating the management of such equipment according to the demand created by the wells, generates an optimization problem. The decision for a rig intervention on a well depends on parameters such as flow rate, depth, wasted time on intervention, distance from the rig to the next well, type of operation, rig capacity, environmental risks, etc. The objective of this paper is to present an interactive Computational System for Support Decision to the optimized management ...

British Library Electronic Table of Contents (United Kingdom)

Background Atrial fibrillation (AF) is the most common sustained atrial arrhythmia and it is independently associated with an increased morbidity and mortality. As a result of the high prevalence of AF, the economic and clinical impact of the disease is substantial. This study describes the economic and clinical impact of AF in the Netherlands. Methods Epidemiological data on AF in the Netherlands were projected on population estimates of the Netherlands in 2009 and combined with data on the cost of AF and its interventions. Results Overall prevalence of AF in the Netherlands is 5.5% in the population over 55?years, corresponding to about 250,000 AF patients. The prevalence increases with age, and the mean age of AF patients is 69.3?years. Incidence of AF in the Netherlands varies with age...

Energy Technology Data Exchange (ETDEWEB)

A method for cleaning timing optimization in a parallel steam generator system is described. The method is based on the minimization of a suitable objective function, and takes into account the load allocation on steam generators. In order to establish appropriate fouling growth models the mechanism of the particle deposition and removal on heat transfer surfaces is analyzed. The objective function is related to the short time management costs which are based on depreciation of steam generators, fuel costs and the costs of cleaning interventions. The optimization problem is described; a direct one level method is compared with a two level method. Some applications and their results are reported and discussed. (author)

British Library Electronic Table of Contents (United Kingdom)

Transdifferentiation of an individual's own cells into functional differentiated cells to replace an organ's lost function would be a personalized approach to therapeutics. In this two part series, we will describe the progress toward establishing functional transdifferentiated adrenal cortical cells. In this article (Part 2), we describe the disorders of the adrenal cortex, therefore establishing why there is the need for personalized cell-based therapy for individuals with these disorders. We then present our pilot studies of cell transdifferentiation toward an adrenal cortical fate using genes described in the first article of this pair (Part 1).

Wastenet

... A better understanding of the links between nutrients, the gut microbiome and the intestinal immune system is likely to pave the way to the development of innovative approaches that target activation of specific immunological pathways for promoting the hostrsquo;s gut defense. Such knowledge should positively impact on the development of vaccine formulations and intervention strategies for improved control of enteric infections in developing countries. Registration fees # The Registration Fee is $715.00 on and before September 7, 2011. # After September 7, 2011, the ...

Energy Technology Data Exchange (ETDEWEB)

The paper considers the main components of energy policy, in particular the challenges of network security of supply, long-term contracts and the environmental constraints. It is argued that the United Kingdom's energy policy should take account of multiple market failures and context dependent. Given energy liberalisation in the 1980s and 1990s, it is argued that interventions based upon market-based instruments should be given greater importance. Institutional reform to reflect the shift in focus towards investment in non-carbon technologies and the security issues associated with networks is proposed, notably the creation of an energy agency. 15 refs., 2 figs.

Energy Technology Data Exchange (ETDEWEB)

CT colonography (CTC) is increasingly advocated as an effective initial screening tool for colorectal cancer. Nowadays, policy-makers are increasingly interested in cost-effectiveness issues. A number of studies assessing the cost-effectiveness of CTC have been published to date. The majority of findings indicate that CTC is probably not cost-effective when colonoscopy is available, but this conclusion is sensitive to a number of key parameters. This review discusses the findings of these studies, and considers those factors which most influence final conclusions, notably intervention costs, compliance rates, effectiveness of colonoscopy, and the assumed prevalence and natural history of diminutive advanced polyps. (orig.)

British Library Electronic Table of Contents (United Kingdom)

Regular physical activity (PA) decreases the risk of several chronic diseases including some cancers, type II diabetes, obesity, and cardiovascular disease; however, the majority of US adults are not meeting the recommended levels to experience these benefits. To address this public health concern, the underlying mechanisms for behavior change need to be understood, translated and disseminated into appropriately tailored interventions. The Transtheoretical Model (TTM) provides a framework for both the conceptualization and the measurement of behavior change, as well as facilitating promotion strategies that are individualized and easily adapted. The purpose of this manuscript is to present the constructs of the TTM as they relate to PA behavior change. We begin with a brief synopsis of rec...

Science.gov (United States)

This study examined whether cognitive behavioural therapy (CBT) could prevent the development or worsening of panic-spectrum psychopathology and anxiety symptoms in chronic obstructive pulmonary disease (COPD). 41 patients with COPD, who had undergone pulmonary rehabilitation, were randomised to either a four-session CBT intervention condition (n = 21) or a routine care condition (n = 20). Assessments were at baseline, post-intervention, and at 6-, 12- and 18-month follow-ups. Primary outcomes were the rates of panic attacks, panic disorder and anxiety symptoms. Secondary outcomes were depressive symptoms, catastrophic cognitions about breathing difficulties, disease-specific quality of life and hospital admission rates. There were no significant differences between the groups on outcome measures at baseline. By the 18-month follow-up assessment, 12 (60%) routine care group participants had experienced at least one panic attack in the previous ...

CERN Document Server

Single-case and Small-n Experimental Designs

Science.gov (United States)

Magnetic forming coil design and development

CERN Document Server

Design and Analysis of Vaccine Studies

British Library Electronic Table of Contents (United Kingdom)

During the design process, designers have to define the structure of their product while considering its functional definition. This design phase remains little assisted for designers. In addition, as numerous options can be considered for the end of life of a product (reuse, remanufacturing, recycling,) it becomes more difficult to obtain a compromise concerning the final structure of the product. In this paper, we will show how the use of virtual reality helps designers to transform the functional definition of the product into the design of its structure, during the conceptual design phase. The developed example will concern the design of a bathroom scale.

Science.gov (United States)

the shear-beam design and the larger scale component test specimen. The subcompo - nents designed were: a. Web splice specimen. ...

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No abstract prepared.

CERN Document Server

The Delft Systems Approach

International Nuclear Information System (INIS)

This report has been prepared in support of the industry effort to standardize nuclear plant designs. These documents describe the Combustion Engineering, Inc. System 80+trademark Standard Design.

CERN Document Server

Professional CSS

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

KoreaScience (Korea)

Full Text Available

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Digital libraries

KoreaScience (Korea)

Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The aim of the paper is to review the role of interventional radiology in the management of hemodialysis vascular access and complications in renal transplantation. The evaluation of patients with hemodialysis vascular access is complex. It includes the radiology/ultrasound (US) evaluation of the peripheral veins of the upper extremities with venous mapping and the evaluation of the central vein prior to the access placement and radiological detection and treatment of the stenosis and thrombosis in misfunctional dialysis fistulas. Preoperative screening enables the identification of a suitable vessel to create a hemodynamically-sound dialysis fistula. Clinical and radiological detection of the hemodynamically significant stenosis or occlusion demands fistulography and endovascular treatment. Endovascular prophylactic dilatation of stenosis greater than 50% with associated clinical abnormalities such as flow-rate reduction is warranted to prolong access patency. The ...

Energy Technology Data Exchange (ETDEWEB)

The objective of the Korean Next Generation Reactor(KNGR) seismic design is to develop a standard design that can cover most of site characteristics in the world with the possible exception of areas of high seismicity. This seismic design was based on the current state-of-the-art as well as the current Nuclear Regulatory guidance. This paper provides a summary on the design parameters used in the KNGR seismic design. In addition, this paper discusses seismic design requirements, selection of generic soil sites, selection of design control motions, and soil-structure interaction(SSI) analyses for the KNGR Nuclear Island(NI) structures. (author). 16 refs., 8 figs.

Science.gov (United States)

... 31 5.4 FACTORIAL DESIGN STATISTICAL ANALYSIS..... ... resistance. o Factorial design statistical analysis gave the ...

British Library Electronic Table of Contents (United Kingdom)

A method for automatic optimal feeder design in steel casting processes is presented. The initial design is the casting part (without feeders) which is placed in a suitable mold box. Design of each feeder contains the following steps: determination of the feeder-neck connection point on the casting surface, initial feeder design, feeder shape optimization and feeder topology optimization. Completing designing the first feeder, the method attends to designing the next one, if it is required, and the same procedure will be repeated. In the presented method, feeders are designed in a descending order of their sizes. The feasibility of the presented method is supported with an illustrative example.

International Nuclear Information System (INIS)

A report is given of a meeting of the Netherlands Association for Energy Legislation (NEVER), which was held in Amsterdam, Netherlands, April 2006. After the meeting a presentation was made about the report 'Government involvement in liberalised gas markets. A welfare-economic analysis of the Dutch gas-depletion policy' of the Netherlands Bureau for Economic Policy Analysis (CPB). This report analyses the welfare effects of two major components of the Dutch gas-depletion policy: the offtake guarantee for small-fields gas and the cap on production from the Groningen field. After the presentation a reaction was given to the report. Both presentations give an overview of the governmental policy and insight in the effects.

International Nuclear Information System (INIS)

Objective: To evaluate the feasibility and clinical application of two stents insertion via single tract for treatment of hepatic hilar cholangiocarcinoma. Methods: Eighteen patients with hepatic hilar cholangiocarcinoma who had left and right bile duct obstruction were treated with stents insertion via right bile duct puncturing routeway. These two stents were implanted between right and left bile duct, and between right bile duct and common bile duct. Results: Eighteen patients obtained successful two stents placement by right bile duct puncturing tract and succeeded with internal drainage for all biliary tree jaundice subsided distinctly. Conclusions: The technique of two stents insertion via single tract could predigest interventional drainage procedure of high bile duct obstruction, reduce operation trauma, shorten handling time and possess promising application value

British Library Electronic Table of Contents (United Kingdom)

Objective: Given the increasing popularity of motorcycle riding and heightened risk of injury or death associated with being a rider, this study explored rider behavior as a determinant of rider safety and, in particular, key beliefs and motivations that influence such behavior. To enhance the effectiveness of future education and training interventions, it is important to understand riders' own views about what influences how they ride. Specifically, this study sought to identify key determinants of riders' behaviors in relation to the social context of riding, including social and identity-related influences relating to the group (group norms and group identity) as well as the self (moral/personal norm and self-identity). Method: Qualitative research was undertaken via group discussions ...

British Library Electronic Table of Contents (United Kingdom)

Abstract Many solute carrier transporters that interact with anticancer agents and contribute to their pharmacokinetics have been shown to be differentially upregulated in cancer cells as a result of adaptive response to altered nutritional requirements. This review focuses on pathophysiological function of membrane transporters responsible for the influx of physiological substances including oligopeptides, amino acids, and organic cations and anions, and summarizes the recent knowledge regarding mechanisms in their gene expressions. Broad substrate specificity of enhanced oligopeptide H+/peptide cotransporter 1 activity in cancer cells is useful for tumor tissue-specific delivery of chemotherapeutic agents and positron emission tomography diagnostic probes. Amino acid transporters such as...

British Library Electronic Table of Contents (United Kingdom)

Abstract Iodine concentrates in gastric tissue and may act as an antioxidant for the stomach. We previously showed that self-reported goiter was associated with significantly increased risk of gastric noncardia adenocarcinoma (GNCA) and nonsignificantly increased risks of gastric cardia adenocarcinoma (GCA) and esophageal squamous cell carcinoma (ESCC) in a prospective case-cohort study in a high-risk population in China. Negatively correlated with iodine levels, serum thyroglobulin (Tg) is a more sensitive biomarker of iodine deficiency than goiter. Our study aimed to determine whether baseline serum Tg was also associated with development of GNCA, GCA and ESCC in the same cohort, the Linxian General Population Nutrition Intervention Trial. Sera from -200 subjects of each case type and 40...

Science.gov (United States)

Serious complications due to coronary artery fistulae have been described. Most authors recommend early intervention at the time of diagnosis. We present a case of a fistula originating from a dilated left coronary artery and draining into the right atrium, which was diagnosed prenatally by color Doppler echocardiography. During pregnancy, the echocardiographic findings remained unchanged, and there were no signs of heart failure. After birth, the fistula was confirmed by angiography. Additionally, a persistent left superior vena cava draining into the coronary sinus and a very small ventricular septal defect were detected. The fistula was closed successfully by transcatheter coil embolization. At 17 months old the child was in good clinical condition. Prenatal diagnosis of coronary artery fistulae may be possible and may improve perinatal management and outcome. PMID:12047543

Energy Technology Data Exchange (ETDEWEB)

Objective: To evaluate the treatment of malignant biliary stenoses and occlusions using a new stent. Methods: In a prospective study, 25 patients with malignant obstructive jaundice were treated with SMART stents. The handling and the quality of stent expansion were documented. Stent function was assessed 2-4 days after intervention by cholangiography and laboratory tests. A follow-up was performed three months, after stent placement. Results: All lesions were treated successfully, with a total of 35 stents implanted. In 14 patients a further balloon dilatation was performed after stent placement (8-10 mm diameter/40-80 mm length). The mean serum bilirubin level decreased significantly from 11.6 mg/dl to 4.6 mg/dl after intervention (p<0.05). The follow-up showed a mean serum bilirubin level at 4.0 mg/dl. In 4 cases (16%) a further intervention (PTCD or stent) was performed. Six patients died due to tumor ...

British Library Electronic Table of Contents (United Kingdom)

Objectives: Many youth with tics experience distress about having tics and how others may perceive them. Such symptoms are often more impairing and distressing than are the tics and negatively impact self-concept, functioning, and quality of life. Although treatments exist that target the frequency and severity of tics, no intervention has been developed that helps youth with tics cope with their condition and limit associated functional impairment and distress. Given this, we developed a cognitive-behaviorally oriented psychotherapy protocol that promotes adaptive coping and resiliency among youth with tics in addressing varied issues commonly experienced by this population. This poster reports data from the Phase I component of this study. Method: Phase I concentrated on developing the t...

Science.gov (United States)

The use of meta-analysis has become increasingly useful for clinical and policy decision making. A recent development in meta-analysis, multiple treatment comparison (MTC) meta-analysis, provides inferences on the comparative effectiveness of interventions that may have never been directly evaluated in clinical trials. This new approach may be confusing for clinicians and methodologists and raises specific challenges relevant to certain areas of medicine. This article addresses the methodological concepts of MTC meta-analysis, including issues of heterogeneity, choice of model, and adequacy of sample sizes. We address domain-specific challenges relevant to disciplines of medicine, including baseline risks of patient populations. We conclude that MTC meta-analysis is a useful tool in the context of comparative effectiveness and requires further study, as its utility and transparency will likely predict its uptake by the research and clinical community.

British Library Electronic Table of Contents (United Kingdom)

ObjectivesTo assess the influence of epigallocatechin-3-gallate (EGCG) on the efficacy of ionizing radiation on prostate cancer cells because of the increased use of dietary interventions, especially by patients with prostate cancer. Radiotherapy is used to treat localized prostate cancer. Some people consume green tea (EGCG) as a chemopreventive agent against prostate cancer. Green tea can act as an antioxidant and induce superoxide dismutase enzymes, which could scavenge the free oxygen radicals generated by radiotherapy. MethodsProstate cancer cell line DU145 cells were treated with EGCG or radiotherapy, or both. Cell death was assessed using trypan blue cell counting, and apoptosis was confirmed by assessing poly (adenosine phosphate ribose) polymerase cleavage. The antioxidant potenti...

British Library Electronic Table of Contents (United Kingdom)

Objective Multiple sclerosis (MS) and its animal counterpart experimental autoimmune encephalomyelitis (EAE) have a major inflammatory component that drives and orchestrates both diseases. One particular group of mediators are the prostaglandins (PGs), which we have previously shown, through quantitation and pharmacological intervention, to be closely involved in the pathology of MS and EAE. The aim of the current study was to determine the expression of the PG-generating cyclooxygenase (COX) enzymes and the profile of PGE2 and PGD2, in selected central nervous system (CNS) tissues, with the development of the chronic relapsing (CR) form of EAE. In particular, the work investigates the possible relationship between the expression of COX isoenzymes and PG levels during the neurological phas...

British Library Electronic Table of Contents (United Kingdom)

Background Despite potentially relevant chemical differences between filtered and boiled coffee, this study is the first to investigate consumption in relation to the risk of incident cancer. Methods Subjects were from the V?sterbotten Intervention Project (64,603 participants, including 3,034 cases), with up to 15?years of follow-up. Hazard ratios (HR) were calculated by multivariate Cox regression. Results No associations were found for all cancer sites combined, or for prostate or colorectal cancer. For breast cancer, boiled coffee ?4 versus <1 occasions/day was associated with a reduced risk (HR?=?0.52, CI?=?0.30?0.88, p trend?=?0.247). An increased risk of premenopausal and a reduced risk of postmenopausal breast cancer were found for both total (HRpremenopausal?=?1.69, CI?=?0.96?2.98...

British Library Electronic Table of Contents (United Kingdom)

Background: Chloroquine has in-vitro activity against influenza and could be an ideal candidate for worldwide prevention of influenza in the period between onset of a pandemic with a virulent influenza strain and the development and widespread dissemination of an effective vaccine. We aimed to assess the efficacy of such an intervention. Methods: In this randomised, double-blind, placebo-controlled trial done at a single centre in Singapore, we randomly assigned (1:1) healthy adults to receive chloroquine phosphate (500 mg/day for 1 week, then once a week to complete 12 weeks) or matching placebo by use of a computer-generated randomisation list. Participants filled an online symptom diary every week, supplemented by daily diaries and self-administered nasal swabs when unwell. Haemagglutin...

Energy Technology Data Exchange (ETDEWEB)

On 10 dialysis patients we performed 12 balloon dilatations, 2 catheter lyses, 6 stent implants (Palmaz stent) and one atherectomy of central venous stenoses or occlusions (v. subclavia, v. brachiocephalica) at the shunt arm of the patient. The primary success rate was, in balloon PTA and lysis, 12/14 interventions, and in stent placement and atherectomy 7/7. The angiographical and clinical primary result after stent implantation was significantly better than after conventional dilatation. After 66% of the balloon dilatations recidivation occurred within the first year; this can be treated by means of repeated PTA. Whether long-term exclusion of recurrence can be achieved by stent implantation, must be established by means of follow-up studies that are at present in progress. (orig.).

British Library Electronic Table of Contents (United Kingdom)

Primary percutaneous coronary intervention (PPCI) is superior to thrombolysis (TL) as reperfusion therapy in ST-elevation myocardial infarction (STEMI). TL is a rapidly available, but semi-effective therapy (effective reperfusion in 50% of patients only), whereas PPCI is a potentially delayed, but highly effective therapy (effective reperfusion in >90%). Since TL loses its efficacy beyond 2?3?h after symptom onset, it is a significant reperfusion alternative to PPCI in early presenters only. The individual decision to treat an early presenter with PPCI or TL requires the evaluation of the time delay between potential start of TL or PPCI, the PCI-related delay (PRD). PRD is greatest, if TL is given in the prehospital setting. Until now, prehospital TL as the most rapidly available reperfusi...

British Library Electronic Table of Contents (United Kingdom)

Background/Purpose Early detection and intervention of psychosis is clinically important. This study aimed to test the applicability of the Chinese version of the Prodromal Questionnaire (CPQ) for identifying prodromal states of psychosis. Methods This is a two-group cross-sectional comparative study. The Prodromal Questionnaire (PQ) was translated into traditional Chinese based on Brislins Revised Model. Like the PQ, the CPQ provides results on four subscales: (1) positive symptoms, (2) negative symptoms, (3) disorganized symptoms, and (4) general symptoms. An expert panel of five senior psychiatrists established the content validity of the CPQ. The experimental group was a sample of 100 first-visit patients to a psychiatric outpatient department (FVPOD). The comparison group comprised 98...

International Nuclear Information System (INIS)

The in-core reload design procedure, computer codes, design contents and comparison between expected design values and measured values for Daya Bay Nuclear Power Station are presented. The in-core reload design for Daya Bay Nuclear Power Station performed by Nuclear Power Institute of China satisfies the requirements of safety and economy. The expected design values are fit well with measured values

CERN Document Server

A class of nonlinear models combining a pharmacokinetic compartmental model and a pharmacodynamic Emax model is introduced. The locally D-optimal (LD) design for a four-parameter composed model is found to be a saturated four-point uniform LD design with the two boundary points of the design space in the LD design support. For a five-parameter composed model, a sufficient condition for the LD design to require the minimum number of sampling time points is derived. Robust LD designs are also investigated for both models. It is found that an LD design with $k$ parameters is equivalent to an LD design with $k-1$ parameters if the linear parameter in the two composed models is a nuisance parameter. Assorted examples of LD designs are presented.

Science.gov (United States)

Background: Anxiety disorders are known to be common in the general population. Previous studies with adults with intellectual disabilities (IDs) report a prevalence of general anxiety disorder ranging from less than 2% to 17.4%. Little is known about associated factors in this population. This study investigates point prevalence of anxiety disorders and determines the factors independently associated with them. Methods: Information was collected with 1023 adults with IDs who participated in a large-scale, population-based study. All had a comprehensive physical and mental health assessment. The point prevalence of anxiety disorders according to different diagnostic criteria was determined, as were independently associated factors by using logistic regression analysis. Results: Three point eight per cent (95% CI = 2.7-5.2%) of the cohort had an anxiety disorder at the time of assessment. Generalised anxiety disorder was the most common (1.7%), then agoraphobia (0.7%). Factors ...

International Nuclear Information System (INIS)

The frequency of peripheral pulmonary artery stenosis in patients after surgical repair of tetralogy of Fallot (TOF) ranges from 20 to 40%. This can be either primary or secondary to the surgical intervention. The influence of resulting lung perfusion alterations on the life quality of patients is difficult to predict. The aim of this study was to compare the utility of the diagnostic procedures in this group of patients, with particular focus on lung perfusion scintigraphy. This study comprised 104 patients who underwent repair of TOF at ages from 5 months to 25 years. The patients have been followed up for from 4.2 to 25 years. On the basis of chest X-ray peripheral pulmonary artery stenosis was suspected in 11 patients, in 12 on the basis of echocardiography examination. Lung perfusion scintigraphy has been performed on 87 patients. The disturbances in lung perfusion (mostly in the left lung) were show by means of lung perfusion scintigraphy in 43 (49%) of ...

DEFF Research Database (Denmark)

Now, more than ever, there are serious health concerns for obese and overweight children. Schools are the perfect setting for children to learn, and this influence can play an important role in preventing children from becoming obese and overweight. The study concerns the behaviors of Health Promoting School (HPS) according to a broad definition of HPS in World Health Organization (WHO), or dependent on schools own health promoting policies. The purpose of study research is to examine whether promoting physical activity among the children at schools in relation to a school health policy such as Food and Nutrition Policy (FNP). This was determined through the comparisons between the FNP based schools and non policy based schools. The study undertook surveys among school food coordinators in the selected Danish primary schools through a web-based questionnaire. The questions in the survey were more focused on physical activity in internal and external school environment. Schools provide ...

Energy Technology Data Exchange (ETDEWEB)

In this paper, power system stabilizer design for multi-machine power systems is translated into an equivalent problem of decentralized controller design for Multi-Output Multi-Input (MIMO) control systems. Subject to a condition based on the structured singular values, each stabilizer can be designed independently. Within this general framework, the conventional stabilizer design methodology based on the concept of synchronous and damping torques is used to decide the design details of each stabilizer. The suggested design method is applied to a model of a practical 10 machine power system. (author)

Energy Technology Data Exchange (ETDEWEB)

Substation machinery foundation works have some features such as a number of work cases second look cases in design, and so forth. The Tohoku Electric Power Co., Inc. started the development of a system generally supporting the substation machinery foundation design to practical use the Engineering Work Station (EWS) introduced to the civil engineering department as a part of improvement of management efficiency. At first, rigid foundation design support system (TRAD) and slab foundation design support system (KANSAS-IN) automatically conductible with from preparation of design and amount calculation sheet to preparation of design drawing was developed, which was began to operate since March of 1996. As a result, the rigid foundation design became able to execute fully automatic works from preparation of design and its ...

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The manual provides design information for four groups of sediment control structures and treatments which are suitable for use on small areas in surface coal mining. A detailed design procedure is given for each group which will estimate the total amount of settleable solids from a small area with a sediment control structure or treatment for a specific design storm. A procedure is also given for estimating the mean annual sediment yield from a small area. Information on design, installation, maintenance and cost is given for each sediment control measure. Methods for determining the maximum allowable area for each sediment control measure and for design of combined sediment control systems are presented. The design procedures contain numerous nomographs, graphs, and worksheets to facilitate the use of the design procedure. The sediment ...

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The conceptual design for MCP to be installed in the integral reactor SMART was carried out. Canned motor pump was adopted in the conceptual design of MCP. Three-dimensional modeling was performed to visualize the conceptual design of the MCP and to check interferences between the parts. The theoretical design procedure for the impeller was developed. The procedures for the flow field and structural analysis of impeller was also developed to assess the design validity and to verify its structural integrity. A computer program to analyze the dynamic characteristics of the rotor shaft of MCP was developed. The rotational speed sensor was designed and its performance test was conducted to verify the possibility of operation. A prototypes of the canned motor was manufactured and tested to confirm the validity of the design concept. The MCP ...

Energy Technology Data Exchange (ETDEWEB)

This report, entitled Combustion Engineering Standard Safety Analysis Report -- Design Certification (CESSAR-DC), has been prepared in support of the industry effort to standardize nuclear plant designs. These volumes describe the Combustion Engineering, Inc. System 80{sup +}{trademark} Standard Design. This volume 8 provides a description of instrumentation and controls.

International Nuclear Information System (INIS)

The Guarantee Outline presents the technical demands of design and contents of assessment for radiation hardening in satellite engineering in China. It includes the basis of design in space environment of polar orbit, the contents of design for general radiation hardening, the requirements and assessments of the single-board computer, the requirements of design for circuits (including hardware and software), the choices and assessments for devices, and the primary stipulations for the requirements of design and assessments against the phenomenon of charge and discharge.

Science.gov (United States)

This is the quarterly progress review report for Wolsung NPP 2, 3, 4 NSSS design and engineering which evaluates the performance of project and describes the project highlight, manpower loading status, design and engineering and project related meeting by...

Science.gov (United States)

The continuing rapid increase in available computing power has not reduced the importance of efficient methods of optical system assessment for automatic lens design. On the contrary, the new capabilities simply show that truly automatic optical design wi...

International Nuclear Information System (INIS)

This talk sketches out the main parameters (technology, circuit design) that have an influence on the hardening of digital CMOS integrated circuits. For each technology the more common defects are mentioned. General design rules are proposed to prevent or limit those defects. (D.L.). 2 refs., 2 figs.

Science.gov (United States)

Contents: Introduction; Design Criteria for a Green Building; Comparison of Energy Efficiency Measures; Whole House Energy Efficiency; Built Examples of Energy Efficient Houses; and Product Energy of Building Elements.

Science.gov (United States)

A substantial design and development program has been underway in the United States of America on the Darrieus vertical axis wind turbine (VAWT). The purpose of this report is to present currently available information on: design, construction, and testin...

Science.gov (United States)

This design manual contains descriptions of design procedures and operating experience to date, including results obtained, for secondary flow pollution control devices. Two types of combined sewer overflow regulators are described: the swirl and the helical bend regulator/separa...

International Nuclear Information System (INIS)

The CANFLEX-NU Fuel Design Report (FDR) for Wolsung 1,2,3,4 was submitted for licensing review in July 1996. The FDR contains sections of fuel rod design, fuel bundle design, nuclear design and thermal-hydraulic design. Each section describes the design bases, design methodology and design evaluation results showing that the design bases are met. The CANFLEX-NU fuel design is not finalized yet in Korean licensing point of view. For example, among others, new Xc-BL correlation is needed to be developed, fuel rod gap reduction effect is to be considered in the Critical Heat Flux, more information for power ramp defect of fuel rod especially in the end-cap weld region is needed in the fuel rod design, and enough data are not available in irradiated conditions in ...

Energy Technology Data Exchange (ETDEWEB)

A comprehensive presentation is made of state-of-the-art configurations and design methodologies for heat transfer devices applicable to industrial processes, automotive systems, air conditioning/refrigeration, cryogenics, and petrochemicals refining. Attention is given to topics in heat exchanger mechanical design, single-phase convection processes, thermal design, two-phase exchanger thermal design, heat-transfer augmentation, and rheological effects. Computerized analysis and design methodologies are presented for the range of heat transfer systems, as well as advanced methods for optimization and performance projection.

Science.gov (United States)

developing a consensus PRA standard for non- associated guidance light water reactor applications that will address some aspects of PRA in design. ...

UK PubMed Central (United Kingdom)

In order to clarify the taxonomic status and to preserve the stability of the species, a neotype is designated for the tuliptree scale: Coccus liriodendri Gmelin (now Toumeyella...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

A pipeless batch plant is a batch processing production system using mobile vessels. The plant performances depend on both hardware of equipment and software of operation. So the plant includes many design factors such as number of vessels, stations and AGVS, layout of stations, vessel moving rules, job scheduling and so on. In this paper, the characteristics of pipeless batch plant design are considered to handle the problem by the systems engineering approach. Then, a practical design method known as design-by-analysis is applied to solve such a complex design problem. Based on this concept, a design support system composed of modeling, simulation and evaluation subsystems is developed. This system enables rational decision making through performance evaluation for proposed design of a pipeless batch plant. The usefulness of the system is ...

International Nuclear Information System (INIS)

This paper presents the development of technical requirements for the design of aircraft-mounted sampling equipment for the airborne radioactivity monitoring. A design concept and internal equipments required for the sampling system will be described in detail to provide information for the development of technical requirements for aircraft-mounted sampling equipment. This will be followed by description of the exterior designing process. Difficulties of designing exterior of the sampling system lie in the fluid dynamics performance of the system. The objective of the design is to maximize the suction flow necessary for achieving high efficiency of radionuclide sampling, while minimizing disturbance to the aircraft which carries the system. The design optimization was performed with the computational fluid dynamics (CFD) code FLUENT. The ...

Science.gov (United States)

2 illustrates the design of the launch tube, the gun barrel design of the multi-tube dispenser and integrated hardware pressure cannister. ...

CERN Document Server

Constraints on target chamber first wall and target designs that will enable NIF debris shields to survive

Science.gov (United States)

consider applying the requirements of MIL-STD-2073-1. 5.2.5. Sustainability. Because of the design control the. Government has had over. XIL-SPEC designs, ...

Energy Technology Data Exchange (ETDEWEB)

A design is proposed for forming the rear screen of a chamber firebox at the point of aerodynamic projection and a design for attaching the pipes of the aerodynamic projection using girders linked with the screen by hinges and movable connections.

Energy Technology Data Exchange (ETDEWEB)

Our group is interested in evaluating early effects of dietary interventions on bone loss. Postmenopausal women lose bone following reduction in estrogen which leads to increased risk of fracture. Traditional means of monitoring bone loss and effectiveness of treatments include changes in bone density, which takes 6 months to years to observe effects, and changes in biochemical markers of bone turnover, which are highly variable and lack specificity. Prelabeling bone with {sup 41}Ca and measuring urinary {sup 41}Ca excretion with accelerator mass spectrometry provides a sensitive, specific, and rapid approach to evaluating effectiveness of treatment. To better understand {sup 41}Ca technology as a tool for measuring effective treatments on reducing bone resorption, we perturbed bone resorption by manipulating dietary calcium in rats. We used {sup 3}H-tetracycline ({sup 3}H-TC) as a proxy for {sup 41}Ca and found that a single dose is feasible to study bone ...

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The purpose of this study was to evaluate the feasibility, efficacy and safety of percutaneous thromboaspiration with a Desilets-Hoffman Sheath compared with the previously established percutaneous mechanical thrombectomy technique in cases of occluded dialysis graft. One hundred and sixty eight patients (103 women, 65 men; mean age, 54.7 years; mean graft age, 20.9 months) with 225 episodes of dialysis graft thrombosis underwent percutaneous thromboaspiration with a 7F Desilets-Hoffman sheath using the crossing catheter or single puncture technique. The technical success rate, procedure time, and complication and patency rates were analyzed. Technical success was achieved in 200 of the 225 procedures (88.9%). The average duration of the intervention was 74.3 {+-} 35 minutes. The primary patency rate was 63.1% at 3 months, 44.2% at 6 months and 26.3% at 1 year. Major complications occurred in 4% of the cases (4 venous ruptures; 4 arterial embolisms; 1 arterial ...

Energy Technology Data Exchange (ETDEWEB)

The synovial and bone uptake of tracer in the knees of patients with rheumatoid arthritis (RA) was quantified using {sup 99}Tc{sup m}-hexamethyl propylene amine oxime-labelled leucocytes and {sup 99}Tc{sup m}-methylene diphosphonate (MDP), respectively. Significant neutrophil migration and MDP uptake occurred in the knees of patients with RA irrespective of the disease duration. In all but one patient neutrophil migration was reduced after intra-articular steroid injection. The change in MDP uptake after steroid injection was variable. There was a significant correlation between the percentage reduction in neutrophil migration and pain score, while the latter correlated poorly with the change in MDP uptake. The quantification of the neutrophil component of the inflammatory process is a sensitive index for monitoring RA activity and response to pharmacological interventions, while quantitative bone scintigraphy should not be employed to monitor changes in joint ...

Energy Technology Data Exchange (ETDEWEB)

The Thai natural rubber economy is described in the context of the world rubber market. An econometric model is estimated for 15 structural equations; it includes the Thai, US, and rest-of-the-world rubber economies. Several simulation experiments are analyzed for the period from 1984 to 1995. Impact and dynamic multipliers are reported for major endogenous variables in response to changes in US GDP, world crude oil price, Thai replanting cess tax and Thai natural rubber production. A 1%, one-time increase in the US GDP has a positive effect on the Singapore natural rubber price. A world crude oil price decline shock has a negative effect in both the short-run and the long-run. The INRO buffer stock stabilization policy as well as alternative domestic Thai policies of market intervention are analyzed. The simulation results show that buffer stock management which allows a price band of +/-20% around the price target has the most stabilized price, compared to other ...

International Nuclear Information System (INIS)

Intracranial atherosclerosis is a major cause of ischemic stroke, and depending on the studied population, it accounts for 8%-15% of all strokes that are due to cerebral atherosclerosis. The prognosis of patients with symptomatic intracranial stenoses seems to depend on the location and extent of intracranial atherosclerosis. Currently, the primary treatment in intracranial atherosclerosis is the control of vascular risk factors such as hypertension, diabetes, hypercholesterolemia, and smoking. Secondary prevention with antiplatelet therapy has been shown to reduce the risk of subsequent vascular events in patients who have suffered a recent ischemic stroke or transient ischemic attack (TIA). Unfortunately, a significant number of patients with intracranial atherosclerosis continue to suffer from repeated strokes or TIA despite maximal medical treatment. Although endovascular revascularization for symptomatic intracranial stenoses remains at the investigational stage and much of the ...

Environmental Research Database

ObjectivesThe overall objective is to establish rigorous and verified means of deploying FACTS devices as damping controllers so that stability limits of a congested grid can be expanded, with confidence, toward to the thermal limits. A key to this is to ensure that damping of oscillatory modes of the system are robust to the acknowledged variations of the system.~%~~%~The goals are:~%~~%~a) to apply model order reduction techniques to realistic grid systems and verify modes are adequately expressed,~%~~% [continued...]DescriptionTraditionally, the phenomena of inter-area oscillation between generation groups, e.g. England and Scotland, has been avoided through operating point constraints on tie-lines and acceptance of operation at less than thermal capacity. The need to support long distance trading makes such constraints unacceptable. Stability problems can be solved dynamically, rather than avoided through planning, by real power ...

Science.gov (United States)

This article provides an historical look at how programs and practices for students with emotional or behavior disorders (E/BD) have been evaluated since 1964, leading to a codified, although not universally recognized, set of recommendations for evaluating best practices for students with E/BD set out by The Peacock Hill Working Group (1991). The authors contend that, in addition to the programmatic features of best practice, the addition of the quality indicators and standards for research in special education add a critical dimension for examining the quality of the scientific research of identified best practices. Taken together, these set of recommendations and quality indicators represent the state of the art in program evaluation for best practice and programs for students with E/BD. The goal of this article is to outline the current recommendations and apply them to current behavior intervention practices to identify how well the field is meeting the ...

Energy Technology Data Exchange (ETDEWEB)

The mortality in undrained abdominal abscesses is high with a mortality rate ranging between 45 and 100%. The outcome in abdominal abscesses, however, has improved due to advances in image guided percutaneous interventional techniques. The main indications for the catheter drainage include treatment or palliation of sepsis associated with an infected fluid collection, and alleviation of the symptoms that may be caused by fluid collections by virtue of their size, like pancreatic pseudocele or lymphocele. The single liver abscesses may be drained with ultrasound guidance only, whereas the multiple abscesses usually require computed tomography (CT) guidance and placement of multiple catheters. The pancreatic abscesses are generally drained routinely and urgently. Non-infected pancreatic pseudocysts may be simply observed unless they are symptomatic or cause problems such as pain or obstruction of the biliary or the gastrointestinal tract. Percutaneous routes that ...

Energy Technology Data Exchange (ETDEWEB)

Digital imaging techniques such as Digital Image Intensifier Radiography and Digital Storage Phosphor (Selenium) Radiography are replacing conventional film-screen radiography more and more. The aim of this development is the extension of diagnostic capabilities and the reduction of side effects such as radiation dose. Conventional film-screen radiography and digital radiography are very different ways of imaging. For digital radiography specific post-processing is the link between imaging conditions and film documentation. Optimisation of the images includes new possibilities of post-processing and a broad range for variation of the dose. Especially in fluoroscopy, dose can be reduced significantly by new technical features like pulsed fluoroscopy. For digital radiography the European guidelines on quality criteria have to be applied to projection radiography, digital subtraction radiography and to fluoroscopy. Further work should lead to a definition of reference values for the dose ...

Energy Technology Data Exchange (ETDEWEB)

Various pollution abatement measures available to combat oil spills were reviewed with emphasis on biodegradation. Microorganisms naturally found in soils and groundwater can efficiently degrade a variety of organic contaminants. For certain sites, local temperature allows the microorganisms to reduce the contaminant concentrations without human intervention. In April 1994, a diesel fuel leak was found at a telecommunication station located in a park. The leak had already contaminated the surrounding soil. The first step of the clean-up procedure was to excavate the contaminated soil, followed by an evaluation to determine the extent of the remaining contamination. It was concluded that by using natural attenuation the deforestation of the remaining affected area could be prevented. In this instance, the natural attenuation process is expected to take five years for completion. 4 refs., 1 tab., 1 fig.

Energy Technology Data Exchange (ETDEWEB)

Children are at higher risk from lead exposure because their developing neural system is susceptible to its neurotoxic effects. We studied lead levels of paints manufactured in Nigeria in 2006. Lead levels in 5 colors of paints, each from different manufacturers were measured using flame-atomic absorption spectroscopy. We found that 96% of the paints had higher than recommended levels of lead. The mean lead level of paints ranged from 84.8 to 50,000 ppm, with mean of 14,500 ppm and median of 15,800 ppm. The main determinant of lead levels was color of the paint. As lead levels in paint sold in the past years in Nigeria are likely to be at least as high as that currently sold, it is likely that many existing houses contain dangerously high levels of lead. Efforts need to be undertaken to assess the presence of high lead levels in existing housing and if detected, intervention programs for eliminating risk of exposure should be developed in addition to measures to ...

Science.gov (United States)

OBJECTIVEThis study describes the development and preliminary psychometric properties of an assessment to quantify the magnitude of an environmental barrier's influence on occupational performance.METHODThe assessment was developed then piloted on a group of 77 older adults before and after an occupational therapy intervention focused on environmental barrier removal. Refinements were made to the assessment before it was evaluated for interrater reliability in a sample of 10 older adults using two raters.RESULTSThe In-Home Occupational Performance Evaluation (I-HOPE) is a performance based measure that evaluates 44 activities in the home. The four subscales of activity participation, client's rating of performance, client's satisfaction with performance, and severity of environmental barriers are sensitive to change in the environment. The internal consistency of the subscales ranged from .77-.85 and ICCs ranged from .99 to 1.0.CONCLUSIONThis preliminary study ...

Energy Technology Data Exchange (ETDEWEB)

An unmanned aerial vehicle called RAVEN, said to be capable of remote tracking of onshore and offshore oil and gas facilities, has been developed by a group of graduate students from Memorial University of Newfoundland. RAVEN is claimed to be capable of performing a number of tasks under its own control without the need for human intervention, including checking onshore pipelines for damage, or scouting the path of hazardous icebergs offshore. The RAVEN was created to meet the need for real time iceberg tracking and early hazard detection, supplementing or replacing the present method of RADARSAT images and tracking by manned aircraft. The RAVEN can be launched from any platform; it can fly under conditions that would be too dangerous for a manned aircraft. Currently in the prototype stage, the first trial flight for the RAVEN is expected to take place in September 2002. The first flight will consist of five GPS waypoints set relatively close together in a pattern ...

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The diagnostic imaging findings in hepatic amoebiasis and the capabilities of percutaneous drainage have already been described but some debate is open on both diagnosis and treatment. It is reported the experience with the ultrasound (US) and Computed Tomography (CT) studies of the hepatic amoebic abscess and its management. [Italian] I reperti con diagnostica per immagini nell'amebiasi epatica e le possibilita' del drenaggio percutaneo sono stati gia' illustrati; esistono tuttavia controversie sul piano sia diagnostico che terapeutico. Obiettivo di questo lavoro e' quello di riportare l'esperienza personale nella diagnostica con ecografia e tomografia computerizzata (TC) e nel trattamento degli ascessi amebici del fegato.

Energy Technology Data Exchange (ETDEWEB)

This report describes the 5 tasks to be covered under this project and compiles budget information. Task 1 is to establish a Plutonium Information Resource, which has been established in Amarillo, Texas. Task 2, Advisory Functions, coordinates studies and activities relating to the disposition of excess weapons-grade plutonium. Task 3, Environmental, Public Health, and Safety, supports soil remediation activities. Task 4, Education and Outreach, is supporting four programs: K--12 education improvement in science and math courses; Academic intervention to identify and encourage high ability high school and middle school students with potential to become scientists and engineers; Graduate education evaluation; and Public outreach programs. Task 5, Plutonium and other Materials Studies, is currently funding two projects for the disposition of high explosives: a feasibility study of burning a mixture of high explosives and other materials in a commercial coal-fired ...

British Library Electronic Table of Contents (United Kingdom)

Genome-wide association studies have linked lung cancer risk with a region of chromosome 15q25.1 containing CHRNA3, CHRNA5 and CHRNB4 encoding a3, a5 and b4 subunits of nicotinic acetylcholine receptors (nAChR), respectively. One of the strongest associations was observed for a non-silent single-nucleotide polymorphism at codon 398 in CHRNA5. Here, we have used pharmacological (antagonists) or genetic (RNA interference) interventions to modulate the activity of CHRNA5 in non-transformed bronchial cells and in lung cancer cell lines. In both cell types, silencing CHRNA5 or inhibiting receptors containing nAChR a5 with a-conotoxin MII exerted a nicotine-like effect, with increased motility and invasiveness in vitro and increasing calcium influx. The effects on motility were enhanced by addit...

Science.gov (United States)

To illustrate the implementation of a bottom-up approach to the study of culture in health disparities, this article describes the development of a cultural cancer screening scale (CCSS) using mixed methodologies. The aim was to identify cultural factors relevant to breast and cervical cancer screening, develop an instrument to assess them and examine its preliminary psychometric properties among Latin American (Latino) and non-Latino White (Anglo) women in Southern California. Seventy-eight Latino and Anglo women participated in semi-structured interviews, which were content coded based on Triandis' methods for the analysis of subjective culture. Based on the emerging cultural elements, items relevant to cancer screening were developed and pilot tested with 161 participants. After the instrument was refined, 314 Latino and Anglo women from various socioeconomic backgrounds completed the CCSS and data were factor analyzed resulting in five cultural factors: cancer screening fatalism, ...

International Nuclear Information System (INIS)

Naturally occurring radionuclides are present in most material. The most common naturally occurring radionuclides in material are those of the uranium and thorium series and potassium-40. This material is commonly referred to as Naturally Occurring Radioactive Material (NORM). In some material the levels of naturally occurring radionuclides are significantly higher, to the extent that regulatory control may be required for radiation protection purposes. Regulation of NORM presents a range of new challenges for both regulators and operators. Unlike more traditional industries dealing with radionuclides, NORM industries have generally not had any radiological oversight and, for example, are not equipped for radiological monitoring. Some consumer goods containing NORM, which have not traditionally been considered as a radiological problem (such as some fertilizers), may require regulation and this may have social and economic consequences. The transport and disposal of NORM are also a ...

Energy Technology Data Exchange (ETDEWEB)

Purpose: Budd-Chiari syndrome is a fairly uncommon disease in Europe. This often leads to its late diagnosis. The syndrome is characterised by portal hypertension and splanchnic congestion due to obstruction of hepatic venous outflow. This paper describes the treatment of three patients with Budd-Chiari syndrome by interventional therapeutic techniques and discusses alternative treatment modalities. Patients and Methods: The first patient presented with veno-occlusive disease and was treated by the placement of a transjugular intrahepatic portosystemic stentshunt. The second patient showed an occlusion of the major hepatic veins. After percutaneous recanalisation, a stent was placed in the right hepatic vein which remained patent. The third patient had a membranous obstruction of the right hepatic vein which was treated by percutaneous balloon dilatation. Results: In all patients the clinical symptoms resolved completely after treatment and no complications were ...

Energy Technology Data Exchange (ETDEWEB)

This paper describes a dissipativity-based framework for the study of low-frequency oscillations in power systems and for power system stabilizer design. This framework leads to a robust controller design formulation, amenable to both H{sub {infinity}} and QFT tools. An illustrating numerical example presents QFT based design for a widely used benchmark two area, four machine power system.

International Nuclear Information System (INIS)

Design considerations are given for the secondary side region of a vertical U-tube nuclear stream generator with an integral preheater. The thermal shield design, the novel recirculating water flow distribution scheme, the high porosity tube supports used in the parallel flow regions, and the U-bend supports are discussed for the Wolsung Plant steam generators. Experimental and analytical development programs undertaken to verify the design features are outlined.

CERN Document Server

Solid-state communications

KoreaScience (Korea)

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Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

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KoreaScience (Korea)

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Science.gov (United States)

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Science.gov (United States)

The Java Mission Evaluation Workstation System (JMEWS) is a collection of applications designed to

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Energy Technology Data Exchange (ETDEWEB)

Abstract Not Provided

British Library Electronic Table of Contents (United Kingdom)

We have designed a local trigger board for the Daya Bay reactor neutrino experiment, which is aimed to measure the neutrino mixing angle sin22?13 with a precision down to 1% level. The local trigger board processes both the total number of coincident photomultiplier tube (PMT) hits and the PMT energy sum to make trigger decisions. With this design, a high trigger probability is achieved to meet the system requirement. The design of the local trigger board is presented.

KoreaScience (Korea)

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KoreaScience (Korea)

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