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1

Benefits of voluntary industry standards: The triumph of experience over regulation  

Voluntary international standards for mining machinery may gradually replace many national regulations. The days of establishing voluntary standards nation by nation, inhibiting the important flow of international trade, could be numbered. This does not mean that nations will cease domestic regulatory activities within their boundaries, but rulemaking will pay considerable attention to voluntary international standards and will likely strive for compatibility with voluntary international standards. International standards setting bodies are developing standards for machine safety. When these standards are complete and adopted, some nations will require machinery to comport with them. International commerce in products that do not conform to these voluntary international standards may be discouraged.

2

Strategic Standardization  

International standardization has become a strategic tool for global firms since new industrial policies emerged in developed countries in the 1980s, which allow firms to easily form a consortium to set industry-wide standards. This standardization has created many consensus standards that change the distribution of added value internationally, and has induced transformation in the international division of labor among the developed and developing countries. Platform business is most eminent in the resulting business ecosystem. It harnesses consensus standards to earn global competitive advantages, based on two practices: adjusting the scope of their knowledge and selecting new business partners who adopt the standards.   

3

Role of international standardization for the safe practice of hydrogen  

The question of standards in general and of international standards in particular, was discussed. Standards were considered useful instruments in promoting interchangeability, compatibility and interoperability of interfaces in today`s global market. International standards were favoured because free trade is a key issue in the widespread dissemination of hydrogen technologies, because international standards make trade between countries easier and fairer, and because the harmonization of standards helps to curb accidents. Various relevant ISO standards (ISO/CD 13984 for liquid hydrogen-land vehicle fuelling system interfaces, ISO/WD 13985 for liquid hydrogen-land vehicle fuel tanks, and ISO/WD 13986 for tank containers for multi-modal transportation of liquid hydrogen) were described. Procedures for proposing new standards and the ISO process for developing a standard were described. On the average, the process from proposal to final publication of an international standard takes about 40 months.

4

Lexicon management and standard formats  

International standards for lexicon formats are in preparation. To a certain extent, the proposed formats converge with prior results of standardization projects. However, their adequacy for (i) lexicon management and (ii) lexicon-driven applications have been little debated in the past, nor are they as a part of the present standardization effort. We examine these issues. IGM has developed XML formats compatible with the emerging international standards, and we report experimental results on large-coverage lexica.

5

Review of the ANSI metafile and virtual device interface standardization activities  

The American National Standards Institute (ANSI) is developing several graphics standards. Two of these standards, the Virtual Device Metafile and the Virtual Device Interface, are reviewed. The purpose, basic concepts, and philosophy of these standards are discussed and contrasted with current practice and the proposed Graphical Kernel System Standard. The proposed Virtual Device Metafile has been accepted by the International Standards Organization as a new WG2 work item.

6

Evaluation of the feasibility of international growth standards for school-aged children and adolescents  

The development of an international growth standard for the screening, surveillance, and monitoring of school-aged children and adolescents has been motivated by 2 contemporaneous events, the global surge in childhood obesity, and the release of a new international growth standard for infants and pr...

7

Biological bases of the maximum permissible exposure levels of the UK laser standard BS 4803 1983  

The use of lasers has increased greatly over the past 15 years or so, to the extent that they are now used routinely in many occupational and public situations. There has been an increasing awareness of the potential hazards presented by lasers and substantial efforts have been made to formulate safety standards. In the UK the relevant Safety Standard is the British Standards Institution Standard BS 4803. This Standard was originally published in 1972 and a revision has recently been published (BS 4803: 1983). The revised standard has been developed using the American National Standards Institute Standard, ANSI Z136.1 (1973 onwards), as a model. In other countries, national standards have been similarly formulated, resulting in a large measure of international agreement through participation in the work of the International Electrotechnical Commission (IEC). The bases of laser safety standards are biophysical data on threshold injury effects, particularly on the retina, and the development of theoretical mode...

8

The adoption of the Eurepgap standard by mango exporters in Piura, Peru  

The significance of standards in international agricultural trade is continuously rising. Due to their complexity, especially private industry standards are often expected to have a negative impact on agricultural export sectors in developing countries. The successful adoption of standards by a broa...

9

An iterative process of global quality improvement: the International Standards for a Safe Practice of Anesthesia 2010  

Purpose To enhance patient safety through contemporaneous and comprehensive standards for a safe practice of anesthesia that augment, enhance, and support similar standards already published by various countries and that provide a resource for countries that have yet to formulate such standards. Standards development The Safe Anesthesia Working Group of the World Health Organization?s ?Safe Surgery Saves Lives? global initiative updated the 1992 International Standards for the Safe Practice of Anaesthesia (Standards) through an iterative process of literature review, consultation, debate, drafting, and refinement. These Standards address, in detail, the organization, support, practices, and infrastructure for anesthesia care. The Standards are grounded in the fundamental principle of safet...

10

Standards meetings calendar-national.  

American National Standards (ANSI Standards) developed by Accredited Standards Committees S1, S2, S3, and S12 in the areas of acoustics, mechanical vibration and shock, bioacoustics, and noise, respectively, are published by the Acoustical Society of America (ASA). In addition to these standards, ASA publishes catalogs of Acoustical Standards, both National and International. To receive copies of the latest Standards catalogs, please contact Susan B. Blaeser.Comments are welcomed on all material in Acoustical Standards News.This Acoustical Standards News section in JASA, as well as the National and International Catalogs of Acoustical Standards, and other information on the Standards Program of the Acoustical Society of America, are available via the ASA home page: http://acousticalsociety.org. PMID:23145639

11

Trends and Development Status of IEC Global Electric Vehicle Standards  

International standardization is an essential issue in allowing the development and deployment of new technologies such as electrically propelled vehicles (battery-electrics, hybrids and fuel cell vehicles). Ongoing work in the field by the International Electrotechnical Commission focuses both on energy storage and charging infrastructure. This paper presents current developments in the field.   

12

Analysis of the Volume of Red Blood Cells: Application of the Expectation-Maximization Algorithm to Grouped Data from the Doubly-Truncated Lognormal Distribution.  

In accordance with general principles recommended by the International Committee for Standardization in Haematology (1982, Journal of Clinical Pathology 35, 1320-1322), the authors have developed statistical methods for the analysis of red cell volume dis...

13

Flanged automatic steam traps. Face to face dimensions  

This paper presents the ISO (International Standard Organization) Norm no. 6554, developed by the CTI (Italian Thermotechnical Committee), to define the face to face dimensions of a range of flanged automatic steam traps.

14

SIMPLE METHOD FOR ESTIMATING POLYCHLORINATED BIPHENYL CONCENTRATIONS ON SOILS AND SEDIMENTS USING SUBCRITICAL WATER EXTRACTION COUPLED WITH SOLID-PHASE MICROEXTRACTION. (R825368)  

A rapid method for estimating polychlorinated biphenyl (PCB) concentrations in contaminated soils and sediments has been developed by coupling static subcritical water extraction with solid-phase microextraction (SPME). Soil, water, and internal standards are placed in a seale...

15

International Standards to Develop and Promote Energy Efficiency and Renewable Energy Sources  

International Standards are a powerful tool for disseminating new technologies and good practices, developing global markets and supporting the harmonization of government policies on energy efficiency and renewable sources on a global scale.

16

EVALUATION OF CRITICAL POINTS IN TECHNOLOGY TRANSFER OF CRYOPRESERVATION PROTOCOLS TO INTERNATIONAL PLANT CONSERVATION LABORATORIES  

Cryopreservation of plant tissues in liquid nitrogen is now used for long-term conservation of vegetatively-propagated crops. Development of standard techniques for cryopreservation is important to the international plant-conservation community for successful implementation of storage protocols in ...

17

OSI Applied to Aeronautical Satellite Mobile Communications in EURATN.  

The future Aeronautical Telecommunication Network ATN being standardized by ICAO (International Civil Aviation Organization) and application of OSI (Open Systems Interconnection) are described. The concepts developed by paper work have reached such a matu...

18

77 FR 24251 - Consensus Standards, Light-Sport Aircraft  

...Administration Consensus Standards, Light-Sport Aircraft AGENCY: Federal Aviation Administration...of the Sport Pilot and Light-Sport Aircraft rule issued July 16, 2004, and effective...International Committee F37 on Light Sport Aircraft developed the new and revised...

19

Simulation and Evaluation of NATO Standardization Agreement (STANAG) 4214.  

An object-oriented simulation model is developed to evaluate the effectiveness of NATO Standardization Agreement (STANAG) 4214, which promulgates the protocol for international telephone call routing and directories for tactical communications. The model ...

20

SAE ARP 866A vs. ISO 9613-1/ANSI S1.26-1995: A Sensitivity Analysis Comparing Two Procedures for Adjusting As-Measured Spectra to Reference Conditions.  

The Society of Automotive Engineers' (SAE) Aerospace Recommended Practice (ARP) No. 866A (866A), and a procedure utilizing pure-tone absorption equations developed in support of the International Organization for Standardization's (ISO) 9613-1 and the Ame...

 
 
 
 
21

An International Urogynecological Association (IUGA) / International Continence Society (ICS) joint terminology and classification of the complications related directly to the insertion of prostheses (meshes, implants, tapes) & grafts in female pelvic floor surgery  

Introduction and hypothesis A terminology and standardized classification has yet to be developed for those complications arising directly from the insertion of synthetic (prostheses) and biological (grafts) materials in female pelvic floor surgery. Methods This report on the above terminology and classification combines the input of members of the Standardization and Terminology Committees of two International Organizations, the International Urogynecological Association (IUGA) and the International Continence Society (ICS) and a Joint IUGA/ICS Working Group on Complications Terminology, assisted at intervals by many expert external referees. An extensive process of 11 rounds of internal and external review took place with exhaustive examination of each aspect of the terminology and class...

22

International Urogynecological Association (IUGA)/International Continence Society (ICS) joint terminology and classification of the complications related to native tissue female pelvic floor surgery  

AbstractIntroduction and Hypothesis A terminology and standardized classification has yet to be developed for those complications related to native tissue female pelvic floor surgery. Methods This report on the terminology and classification combines the input of members of the Standardization and Terminology Committees of two International Organizations, the International Urogynecological Association (IUGA) and the International Continence Society (ICS) and a Joint IUGA/ICS Working Group on Complications Terminology, assisted at intervals by many external referees. A process of rounds of internal and external review took place with decision-making by collective opinion (consensus). Results A terminology and classification of complications related to native tissue female pelvic floor surge...

23

An international urogynecological association (IUGA)/international continence society (ICS) joint terminology and classification of the complications related directly to the insertion of prostheses (meshes, implants, tapes) and grafts in female pelvic floor surgery  

AbstractIntroduction and hypothesis A terminology and standardized classification has yet to be developed for those complications arising directly from the insertion of synthetic (prostheses) and biological (grafts) materials in female pelvic floor surgery. Methods This report on the above terminology and classification combines the input of members of the Standardization and Terminology Committees of two International Organizations, the International Urogynecological Association (IUGA) and the International Continence Society (ICS) and a Joint IUGA/ICS Working Group on Complications Terminology, assisted at intervals by many expert external referees. An extensive process of 11 rounds of internal and external review took place with exhaustive examination of each aspect of the terminology a...

24

An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint terminology and classification of the complications related to native tissue female pelvic floor surgery  

Introduction and hypothesis A terminology and standardized classification has yet to be developed for those complications related to native tissue female pelvic floor surgery. Methods This report on the terminology and classification combines the input of members of the Standardization and Terminology Committees of two International Organizations, the International Urogynecological Association (IUGA) and the International Continence Society (ICS) and a Joint IUGA/ICS Working Group on Complications Terminology, assisted at intervals by many external referees. A process of rounds of internal and external review took place with decision making by collective opinion (consensus). Results A terminology and classification of complications related to native tissue female pelvic floor surgery has b...

25

1997 DOE technical standards program workshop: Proceedings  

The Department of Energy held its annual Technical Standards Program Workshop on July 8--10, 1997, at the Loews L`Enfant Plaza Hotel in Washington, DC. The workshop focused on aspects of implementation of the National Technology Transfer and Advancement Act of 1995 [Public Law (PL) 104-113] and the related revision (still pending) to OMB Circular A119 (OMB A119), Federal Participation in the Development and Use of Voluntary Standards. It also addressed DOE`s efforts in transitioning to a standards-based operating culture, and, through this transition, to change from a developer of internal technical standards to a customer of external technical standards. The workshop was designed to provide a forum to better understand how the new law is affecting Department activities. Panel topics such as ``Public Law 104-113 and Its Influence on Federal Agency Standards Activities`` and ``Update on Global Standards Issues`` provided insight on both the internal and external effects of the new law. Keynote speaker Richard Meier of Meadowbrook International (and formerly the Deputy Assistant US Trade Representative) addressed the subject of international trade balance statistics. He pointed out that increases in US export figures do not necessarily indicate increases in employment. Rather, increased employment results from product growth. Mr Meier also discussed issues such as the US migration to the sue of the metric system, the impact of budget limitations on Government participation in voluntary standards organizations, international standards ISO 9000 and ISO 14000, and DOE`s role in the worldwide transition from weapons production to cleanup.

26

The Process of Developing National Standards That Meet ANSI Guidelines.  

American national standards for the evaluation of educational programs were developed by the Joint Committee on Standards for Educational Evaluation in 1994. This paper describes the Joint Committee's standard setting process. The Joint Committee is a coalition of professional organizations concerned with the quality of evaluations in education. The operating procedures of the Joint Committee have been accredited by the American National Standards Institute (ANSI). The following standard setting procedures of the Joint Committee have been accepted by the ANSI: (1) initiation of projects by Committee approval; (2) development of a first draft through a national panel; (3) the formation of national and international review panels; (4) field test of the standards; (5) national public hearings; (6) finalization of the standards developed; and (7) consideration of views and opinions. The Joint Committee's standard setting process provides an open consensus process for professionals to use in setting and maintaining evaluation standards. A list of sponsoring organizations is attached. (SLD)

27

Semi-quantitative estimation of the walnut content in fillings of bakery products using real-time polymerase chain reaction with internal standard material  

A method for absolute quantification of walnuts in fillings of bakery products was developed. Macadamia nuts were used as an internal standard material. A duplex real-time polymerase chain reaction (PCR) with 5â?²-nuclease (TaqMan) probes labelled with FAM and JOE for walnuts and the internal standard, respectively, was used. Difference between threshold cycle values (Î?c T) for the analyte and the internal standard, plotted against logarithm of contents, was used to construct the calibration line. A level of 5 % (w/w) of the internal standard material was found to be suitable for quantification of walnuts in nut fillings, the calibration line being linear. The developed method was applied to bakery products from the market, and crucial factors for its routine applicability have been iden...

28

The acid rain sourcebook  

A reference collection of specialized information discussions on areas critical to the acid rain issue: problem definition, impact of legislation, emissions standards, international perspective, cost scenarios, and engineering solutions. The text is reinforced with 130 illustrations and about 50 tables. Contents: International mitigation programs. Emissions reduction: before combustion; during combustion; after combustion. Engineering solutions under development.

29

Enrichment Followed by Quantitative PCR both for Rapid Detection and as a Tool for Quantitative Risk Assessment of Food-Borne Thermotolerant Campylobacters  

As part of a large international project for standardization of PCR (Food-PCR; www.pcr.dk), a multiplex, multiplatform, ready-to-go enrichment followed by a real-time PCR method, including an internal amplification control, was developed for detection of food-borne thermotolerant campylobacters in c...

30

Experts mull over radioactive waste disposal. [International symposium on management of wastes from LWR fuel cycle  

The experts met last month in Denver at an International Symposium on the Management of Wastes from the LWR fuel cycle. Development of nuclear power and reprocessing of the resulting waste in the European countries and the U.S. are discussed. The need for international cooperation and standards is pointed out. Decommissioning of old reactors and facilities is also considered. (DLC)

31

International Standards Development for Marine and Hydrokinetic Renewable Energy - Final Report on Technical Status  

This report summarizes the progress toward development of International Standards for Marine and Hydrokinetic Renewable Energy, as funded by the U.S. Department of Energy (DOE) under the International Electrotechnical Commission (IEC) Technical Committee 114. The project has three main objectives: 1. Provide funding to support participation of key U.S. industry technical experts in 6 (originally 4) international working groups and/or project teams (the primary standards-making committees) and to attend technical meetings to ensure greater U.S. involvement in the development of these standards. 2. Provide a report to DOE and industry stakeholders summarizing the IEC standards development process for marine and hydrokinetic renewable energy, new international standards and their justifications, and provide standards guidance to industry members. 3. Provide a semi-annual (web-based) newsletter to the marine renewable energy community. The newsletter will educate industry members and stakeholders about the processes, progress, and needs of the US efforts to support the international standards development effort. The newsletter is available at www.TC114.us

32

National Agenda for Hydrogen Codes and Standards  

This paper provides an overview of hydrogen codes and standards with an emphasis on the national effort supported and managed by the U.S. Department of Energy (DOE). With the help and cooperation of standards and model code development organizations, industry, and other interested parties, DOE has established a coordinated national agenda for hydrogen and fuel cell codes and standards. With the adoption of the Research, Development, and Demonstration Roadmap and with its implementation through the Codes and Standards Technical Team, DOE helps strengthen the scientific basis for requirements incorporated in codes and standards that, in turn, will facilitate international market receptivity for hydrogen and fuel cell technologies.

33

OSI Network Management.  

Management of heterogeneous networks is complicated by the persistence of proprietary management schemes. The need for integration of network management capabilities is pressing. The International Organization for Standardization is developing standards for managing networks as part of the Open Systems Interconnection (OSI) effort. OSI management functionality includes configuration, fault, performance, accounting, and security. (SD)

34

Emerging standards with application to accelerator safety systems  

This paper addresses international standards which can be applied to the requirements for accelerator personnel safety systems. Particular emphasis is given to standards which specify requirements for safety interlock systems which employ programmable electronic subsystems. The work draws on methodologies currently under development for the medical, process control, and nuclear industries.

35

Ceramic characterization  

Objective of this task is to measure and characterize the ceramic properties (crystalline phase composition, grain boundaries, residual stresses) of a series of standard ceramic specimens to assist in developing international standards for ceramic characterization. This report describes electron microscopy of the microstructure and grain boundaries of ESK silicon carbide; supporting x-ray diffraction data for the bulk phase composition is included.

36

International Standardization of Encryption Algorithms: Cryptographic Standards and Politics of Information Security  

Cryptographic techniques are an important means by which security of information and info-communication networks is ensured. Yet it was not until the mid-2000s that the world's largest developer of standards, the International Organization for Standardization (ISO), issued ISO/IEC 18033 on encryption algorithms.The purpose of this article is to explore a relatively understudied aspect of international standardization by focusing on demand for encryption standards. Drawing on the global governance literature, it argues that the demand for cryptographic standards may be generated not only to address the coordinating problem of technological compatibility but also to address the common problem of information security.It is assumed that the demand for international cryptographic standards will be generated by the businesses, particularly those engaged in electronic commerce, as they are interested in enhancing the security of the network where they hold transactions. It is also assumed that on-line privacy advocates will support the standardization of encryption techniques. However, the commercial interests in cryptographic standardization may be in conflict with national security interests. Just as encryption technology can be used to protect financial information and personal data, it can be used to protect confidential information of foreign governments and other organizations. Therefore, spread of cryptographic techniques through standardization can be detrimental to national security activities.Indeed, ISO's early attempt to establish encryption algorithm standard was frustrated by the objection raised by the US government, which was concerned with the standard's implication to national security. In the 1990s, however, the international business community began to pressure government hard to liberalize cryptographic use so that they could take full advantage of the commercial opportunities provided by the exponential growth to the Internet. The commercial interests succeeded in having its preferences reflected in the Organization for Economic Cooperation and Development (OECD) Guideline for Cryptographic Policy of 1997. The guideline, in turn, provided the ISO with an opportunity to launch once-prohibited standardization of encryption technology as it recommended the setting of standards for cryptographic methods at national and international levels. The ISO eventually produced ISO/IEC 18033 to promote the deployment of “state-of-the-art” encryption technology worldwide.Standards and standardization are often dismissed as technological details in the study of International Relations. However, international standardization of encryption sheds light on the new security dilemma in the information age. Most important of all, the evolution of international cryptographic standards highlights the changing balance between national security and commercial interests in encryption.   

37

Marine terminal baseline criteria and assessment OCIMF; Avaliacao de terminais maritimos - criterio OCIMF  

The development of PETROBRAS Transporte S.A. corporate standards, specifically meant for the marine terminals segment and based on the 'Marine Terminal Baseline Criteria and Assessment Questionnaire', published by 'Oil Companies International Marine Forum' was accomplished by a Team of in-house staff with the assistance of international outsourced consultancy. This project resulted in the adjustment of the company's processes to international practices enabling consistent management and operating assessment of marine terminals. (author)

38

Technical standards and legal requirements for wind turbines: A global overview  

Recent events and developments in the global wind energy scene relating to safety and emergence of specific individual national technical criteria and standards like in India have raised the need for having an international standardization and harmonization for wind turbines. There have been attempts by the International Electrotechnical Commission (IEC) globally and European Union`s European Wind Turbine Standards (EWTS) project regionally, to develop international standards for wind turbines. Some leading nations in wind energy development like Germany, Netherlands and Denmark in Europe have their own national standards and policies. Other leading nations like the USA and India are moving towards having national legal and technical requirements. Against this backdrop, the paper examines the features of various national requirements for wind turbines existing in the leading countries viz. USA, Germany, India, Denmark and Netherlands. The initiatives towards international standardization like the IEC initiative and the EWTS project are also examined. An attempt is also made to evaluate the need for such common international standards vis-a-vis individual national technical and legal requirements.

39

77 FR 37361 - National Emission Standards for Hazardous Air Pollutants for Reciprocating Internal Combustion...  

...Pollutants for Reciprocating Internal Combustion Engines; New Source Performance Standards for Stationary Internal Combustion Engines AGENCY: Environmental Protection...Pollutants for Reciprocating Internal Combustion Engines; New Source...

40

New standards prepare the way for business opportunities in photovoltaics  

Canada`s role in the development of standards for photovoltaic systems through its participation in the International Electrotechnical Commission`s (IEC) Committee on Solar Photovoltaics (TC82) was discussed. The relationships of standards in general in helping to prepare the way for business opportunities around the world, and their role in creating a stable technical framework within which business can be conducted, were reviewed. Standards currently under development by TC82`s Working Group (WG) No.3, the reasons for them, their relationship to commerce, and their importance in the development of the photovoltaic industry and technology world-wide, were scrutinized. The general conclusion was that Canada has significant impact on the development of international standards and is well served by those who represent Canada to ensure that these standards fit Canadian conditions and practices. 3 refs., 3 figs.

 
 
 
 
41

The International Standards Organisation offshore structures standard  

The International Standards Organisation has initiated a program to develop a suite of ISO Codes and Standards for the Oil Industry. The Offshore Structures Standard is one of seven topics being addressed. The scope of the standard will encompass fixed steel and concrete structures, floating structures, Arctic structures and the site specific assessment of mobile drilling and accommodation units. The standard will use as base documents the existing recommended practices and standards most frequently used for each type of structure, and will develop them to incorporate best published and recognized practice and knowledge where it provides a significant improvement on the base document. Work on the Code has commenced under the direction of an internationally constituted sub-committee comprising representatives from most of the countries with a substantial offshore oil and gas industry. This paper outlines the background to the code and the format, content and work program.

42

SPICE in retrospect: Developing a standard for process assessment  

The SPICE Project was established in 1993 to support the development, validation and transition into use of an International Standard for software process assessment. Its efforts have resulted in the publication of a five-part Standard for Process Assessment, ISO/IEC 15504. This paper reviews the evolution of the Standard, and reflects on the parallel achievements of the SPICE Project and the standardisation effort in advancing the state of the art in process assessment and improvement.

43

ANSI (American National Standards Institute) standards in the are of radiation protection  

The American National Standards Institute (ANSI) is the organization responsible for promulgating voluntary consensus standards in a large number of fields. Although nongovernmental, it serves a quasi-official function in representing the United States in international standards activities. ANSI carries out its mandate through liaison with a variety of expert committees, sponsored by professional organizations that recommend consensus standards for adoption as American National Standards in accordance with processes specified by ANSI. Adherence to these processes is important to avoid legal difficulties. Committee N13, sponsored by the Health Physics Society is authorized to recommend consensus standards in the field to ANSI for their approval as American National Standards for Radiation Protection. The committee also reviews existing standards on a 5-yr cycle to ensure they are up to date. The goal of Committee N13 is the development of a coherent set of National Radiation Protection Standards. Recent progress and activities are discussed.

44

Vitamin D status as an international issue: National surveys and the problem of standardization  

Abstract Wide spread variation in measurement results of total 25-hydroxyvitamin D (25(OH)D) confounds international efforts to develop evidence-based clinical guidelines. Accordingly, NIH Office of Dietary Supplements (ODS) in collaboration with CDC National Center for Environmental Health (NCEH), National Institute of Standards and Technology (NIST) and Ghent University established the Vitamin D Standardization Program (VDSP) in November 2010. VDSP objectives include: (1) standardize 25(OH)D concentration measurements in national health surveys around the world, (2) evaluate survey differences, (3) extend standardization efforts to assay manufacturers, and to clinical, commercial, and research laboratories, (4) promote standardization of emerging metabolites of vitamin D status, and (5) ...

45

Quantitative 1H-NMR spectrometry method for quality control of Aloe vera products.  

An 1H-NMR spectrometry method was developed and validated to quantify acetylated polysaccharides, glucose, malic acid, lactic acid, and acetic acid in Aloe vera products. Nicotinamide was selected as an internal standard (IS) in this quantification method. The quantity of marker compounds was calculated by the relative ratio of the integrals of each compound to the IS. The method validation included specificity, linearity, accuracy, robustness, reproducibility, LOD, and LOQ on two samples--A. vera inner leaf standard and decolorized aloe whole leaf Standard from the International Aloe Science Council. Eighteen A. vera commercial products were analyzed with this NMR spectrometry method. PMID:20629385

46

The 32-kb/s ADPCM coding standard  

AT and T has played a major role in the development of national and international standards for 32-kb/s adaptive differential pulse code modulation (ADPCM). This paper highlights the process leading to the standards on 32-kb/s ADPCM recognized by the American National Standards Institute (ANSI) and the International Telephone and Telegraph Consultative Committee (CCITT). The paper briefly describes the algorithm itself and it performance. It concludes with a discussion of applications of ADPCM and the AT and T products and services that utilize ADPCM.

47

Molecular Approaches to Allergen Standardization  

Molecular approaches to allergen standardization include the development of purified natural or recombinant allergen standards whose structural and allergenic properties have been validated, in tandem with certified immunoassays for allergen measurement. Purified allergens can be used individually or incorporated into multiple allergen standards. Multicenter international collaborative studies are required to validate candidate allergen standards and immunoassays, as a prelude to being approved by regulatory agencies. Mass spectrometry is a sophisticated and powerful proteomics tool that is being developed for allergen analysis. Recent results using pollen allergens show that mass spectrometry can identify and measure specific allergens in a complex mixture and can provide precise informat...

48

Status of cool roof standards in the United States  

Since 1999, several widely used building energy efficiency standards, including ASHRAE 90.1, ASHRAE 90.2, the International Energy Conservation Code, and California's Title 24 have adopted cool roof credits or requirements. We review the technical development of cool roof provisions in the ASHRAE 90.1, ASHRAE 90.2, and California Title 24 standards, and discuss the treatment of cool roofs in other standards and energy-efficiency programs. The techniques used to develop the ASHRAE and Title 24 cool roof provisions can be used as models to address cool roofs in building energy standards worldwide.

49

Medical tourism-A New Arena.  

Globalisation has given birth to medical tourism. Health and medical tourism are the fastest growing segments in not only developed nations but in developing countries too. India has become a hot destination, as the Indian medical standards match up to the highly prescribed international standards at a very low cost. However, it is an unmixed blessing; along with advantages, it has many unintended side effects also. PMID:23113017

50

The social cost of smoking in Singapore  

Globalisation has given birth to medical tourism. Health and medical tourism are the fastest growing segments in not only developed nations but in developing countries too. India has become a hot destination, as the Indian medical standards match up to the highly prescribed international standards at a very low cost. However, it is an unmixed blessing; along with advantages, it has many unintended side effects also. PMID:12437040

51

Measuring the effectiveness of international environmental regimes  

While past research has emphasized the importance of international regimes for international governance, systematic assessments of regime effects are missing. This article derives a standardized measurement concept for the effectiveness of international environmental regimes by developing an operational rational choice calculus to evaluate actual policy simultaneously against a non-regime counterfactual and a collective optimum. Subsequently, the empirical feasibility of the measurement instrument is demonstrated by way of two international treaties regulating transboundary air pollution in Europe. The results demonstrate that the regimes indeed show positive effects - but fall substantially short of the collective optima. (orig.)

52

International standards for electric disturbances  

This presentation provided a definition of electromagnetic compatibility (EMC), reviewed disturbances, such as flicker, overvoltage, harmonics, imbalance, dips and sags, and relevant standards, outlined a scheme of how electromagnetic standards should be applied, discussed target areas, including the environment, emissions, immunity, the International Electrotechnical Commission`s (IEC) 61000 standards structure, the status of EMC standards in Canada, Hydro-Quebec standards and EMC, and other relevant standards on EMC. The lack of compatibility and the differences in acceptance levels of the various standards have been identified as a major source of the problems and the increasing cost incurred by industry as a result of lost production. The importance of EMC standards is that they have been developed specifically to provide the information needed to obtain an appropriate level of compatibility between electricity supply and demand. Existing problems could be resolved if everyone played their respective parts. figs.

53

Ergonomics and occupational safety and health: An ILO perspective  

The ILO has a mandate to protect workers against sickness, diseases and injuries due to workplace hazards and risks including ergonomic and work organization risk factors. One of the main functions for the ILO is to develop international standards related to labour and work. ILO standards have exerted considerable influence on the laws and regulations of member States. The ILO standards take the form of international Conventions and Recommendations. ILO Conventions and Recommendations relevant to protection of workers against ergonomic risk factors at the workplace include Convention No. 127 and Recommendation No.128 which specify the international requirements concerning the manual transport of a load. To help member States in applying the ILO standards, the ILO produces practical guides ...

54

Developing Standards-Based Geography Curricular Materials from Overseas Field Experiences for K-12 Teachers  

Overseas experiences provide educators with exceptional opportunities to incorporate field study, firsthand experiences, and tangible artifacts into the classroom. Despite this potential, teachers must consider curricular standards that direct how such international endeavors can be integrated. Furthermore, geography curriculum development is more relevant when teachers link tangible local processes and events with those occurring in distant world regions. As such, this article demonstrates how a structured international field experience for K-12 educators incorporated geography curricular standards, and population geography as a common theme, to develop widely transferable curricular materials that advance students' understanding of Chile and Latin American area studies. (Contains 2 tables, 1 figure and 3 notes.)

55

Providing Pressurized Gasses to the International Space Station (ISS): Developing a Composite Overwrapped Pressure Vessel (COPV) for the Safe Transport of Oxygen and Nitrogen  

To supply oxygen and nitrogen to the International Space Station, a COPV tank is being developed to meet requirements beyond that which have been flown. In order to "Ship Full' and support compatibility with a range of launch site operations, the vessel was designed for certification to International Standards (ISO) that have a different approach than current NASA certification approaches. These requirements were in addition to existing NASA certification standards had to be met. Initial risk-reduction development tests have been successful. Qualification is in progress.

56

The establishment of quality systems in veterinary diagnostic testing laboratories in developing countries: experiences with the FAO/IAEA External Quality Assurance Programme  

Quality systems, established to internationally accepted standards, are one mechanism that can assist in evaluations of the sustainability of technology transfer, the proficiency of the user, and the reliability and comparability of data generated, resulting in potential enhancement of laboratory credibility. The means of interpreting existing standards and implementing quality systems in developing country veterinary diagnostic laboratories has become a significant adjunct to the technology transfer element within the Food and Agriculture/ International Atomic Energy Agency, FAO/IAEA programme. The FAO/IAEA External Quality Assurance Programme (EQAP) is given as an example for an initial step towards enhancing the ?quality?? culture in developing country veterinary laboratories. In 1995 t...

57

International standardization -- Changing the future of the oil and gas industry  

Suppliers to the Oil and Gas Industry have become accustomed to compliance to mandatory and voluntary programs such as quality system requirements, international standards developed by ISO, industry training programs, Occupation, Safety and Hazard Association (OSHA) requirements, and environmental requirements. However, the real impact to the industry will come through international standardization and certification methods, also known as the International Conformity Assessment Movement. This impact will make domestic efforts appear pale by comparison and will be an eye opening experience if US suppliers do not seriously monitor or become involved in what is happening internationally. The International Conformity Assessment Movement is a series of movements which will virtually affect all suppliers of oilfield and gas equipment and services in one way or another. The impact will be felt through one or more of the following ways: (1) ISO 9000 series quality system registration; (2) oilfield product certification as outlined in ISO/TC 67 WG2 documents; (3) design methodologies for oilfield equipment as outlined in ISO/TC 67; (4) European directive compliance; (5) replacement of Domestic Standards with International Standards. The conditions for which compliance is mandatory will vary from company to company and may depend upon the geographical area in which the supplier operates or supplies product. The paper discusses all five systems of standards and lists sources for further information.

58

Radioactive materials packaging standards and regulations: Making sense of it all  

Numerous regulations and standards, both national and international, apply to the packaging and transportation of radioactive material. These are legal and technical prerequisites to practically every action that a designer or user of a radioactive material transportation package will perform. The identity and applicability of these requirements and the bodies that formulate them are also not readily understood. This paper addresses the roles that various international bodies play in developing and implementing the various regulations and standards. It uses the US regulatory and standards-making bodies to illustrate how international requirements feed the domestic control of packaging and transport. It explains the scope and interactions between domestic and international regulatory and standards agencies and summarizes the status and major standards activities at the international level. The overview provided by this paper will be valuable to designers and users of radioactive material packages for better understanding and use of both standards and regulations, and for complying with regulatory requirements in the radioactive materials transportation field. 11 refs., 2 figs.

59

Canada`s participation in the International ElectroTechnical Commission`s (IEC) PV systems technical committees  

Canada`s participation in the development and setting of international standards for the testing and installation of photovoltaic systems was reviewed. The International ElectroTechnical Commission (IEC) is the standard setting body. The Commission has a number of committees. The TC82 Committee has a mandate to develop solar photovoltaic standards. Canada is a member of Working Group No. 3 (WG3) of TC82. Other members of WG3 are Austria, the European Commission, France, Germany, Japan, Mexico, the Netherlands, Switzerland, the UK, and the USA. Canada is the Project Leader for two new standards: the Standards for Photovoltaic Systems on Buildings and the Guidelines for Commissioning Stand-Alone and Grid-Connected PV Systems. Both these standards are in the draft stage. A brief summary of the last two meetings of WG3 was given along with a list of completed standards and a list of new work item proposals. The benefits of Canadian participation in this international standard-setting body was also reviewed. 3 refs.,

60

FY 1999 Report on the technical results. Research and development project for quick-effect type international standards for creating new industries (Standardization of the wireless IC tags for logistics management); 1999 nendo sokkogata kokusai hyojun sosei kenkyu kaihatsu jigyo seika hokokusho. Butsuryuyo musen IC tag no hyojunka  

Spread/expansion of the radio frequency identification (RFID) system application technologies needs the international standards. In order to internationally promote spread/expansion of the RFID system application technologies, Japan has established the examination promotion organization with the participation of the advanced Japanese makers in development of the RFID technologies, representative application users of the distribution logistics and RFID technology standardization deliberative council. The elementary and application RFID technologies are studied and developed, and the results are demonstrated. The organization plans to propose the application requirement profile (ARP) specification drafts to WD (WI/18001) of the ARP, currently deliberated by ISO/IEC JTC1/SC31/WG4/ARP of International Standardization Organization. The organization also plans to submit the Air Interface specification drafts with frequencies of 125kHz and 2.54GHz to the WD (WI/18000) of JTC1/SC31/WG4/SG3. (NEDO)

 
 
 
 
61

International standards for the indoor environment. Where are we and do they apply to Asian countries?  

On the international level, ISO (International Organization for Standardization), CEN (European Committee for Standardization) and ASHRAE (American Society of Heating, Refrigerating and Air Conditioning Engineers) are writing and reviewing standards relating to the indoor environment on a regular basis. This presentation will focus on the development of standards for the indoor thermal environment and indoor air quality (ventilation). In the future, recommendations for acceptable indoor environments will be specified as classes. This allows for national differences in the requirements as well as for designing buildings for different quality levels. Several of these standards have been developed mainly by experts from Europe, North America and Japan. Are there, however, special considerations relating to South-East Asia (lifestyle, outdoor climate, economy) that are not dealt with in these standards and that will require the revision of existing standards? Critical issues are adaptation, the effect of increased air velocity, humidity, type of indoor pollutant sources, etc. The paper will present an overview of existing methods and discuss areas where revision of present standards or the development of new standards are needed, relating especially to conditions in Asia.

62

Comparison of NFPA and ISO approaches for evaluating separation distances  

The development of a set of safety codes and standards for hydrogen facilities is necessary to ensure they are designed and operated safely. To help ensure that a hydrogen facility meets an acceptable level of risk, code and standard development organizations (SDOs) are utilizing risk-informed concepts in developing hydrogen codes and standards. Two SDOs, the National Fire Protection Association (NFPA) and the International Organization for Standardization (ISO) through its Technical Committee (TC) 197 on hydrogen technologies have been developing standards for gaseous hydrogen facilities that specify the facilities have certain safety features, use equipment made of material suitable for a hydrogen environment, and have specified separation distances. Under Department of Energy funding, S...

63

International ship pollution law: recent developments at UNCLOS  

This article examines the implications of the development of international ship pollution law by assessing the draft Articles on ship-sourced pollution at the UN Conference on the Law of the Sea (UNCLOS). The standards and principles in international Conventions presently in force are subject primarily to enforcement only by the flag state. But principles emerging at UNCLOS of coastal state and port state jurisdiction have important ramifications for application and enforcement of pollution law.

64

The effects of International Financial Reporting Standards on the notes of auditors  

Purpose - This paper attempts to combine the developments in the accounting area with those in the auditing area. More specifically, it presents the effects of International Accounting Standards (IAS) on the auditor findings and report. Design/methodology/approach - International Standards on Auditing (ISA) are revised in order to be accepted by the European Union as the common and formal auditing standards of the member states. The introduction of IAS has been one of the most significant developments in the history of the financial statements preparation and presentation. The effects of the application of these standards are present both on the valuation of the firm and on the presentation of its "true and fair view". An extended analysis of the financial statements and the auditor report...

65

Instrumentation for Nuclear Applications  

The objective of this project was to develop and coordinate nuclear instrumentation standards with resulting economies for the nuclear and radiation fields. There was particular emphasis on coordination and management of the Nuclear Instrument Module (NIM) System, U.S. activity involving the CAMAC international standard dataway system, the FASTBUS modular high-speed data acquisition and control system and processing and management of national nuclear instrumentation and detector standards, as well as a modest amount of assistance and consultation services to the Pollutant Characterization and Safety Research Division of the Office of Health and Environmental Research. The principal accomplishments were the development and maintenance of the NIM instrumentation system that is the predominant instrumentation system in the nuclear and radiation fields worldwide, the CAMAC digital interface system in coordination with the ESONE Committee of European Laboratories, the FASTBUS high-speed system and numerous national and international nuclear instrumentation standards.

66

Exploration of Ways to Improve the Quality of Chinese CE Providers  

Facing the development of the 21st century, Chinese government and CE Providers have realized the importance and the urgency of continuing engineering education. China has over 50000 continuing education institutions of various scales and levels. The education quality and teaching measures of those institutions are varied and there is a big gap comparing with developed countries. Such weaknesses as the insufficient investment from the government, incompetence of the teachers, irregular standards for the execution and the inadequate quality evaluation have seriously restricted the development. Evaluation of various continuing education institutions in some Latin and European countries have been conducted in the past few years by adopting different executive models and evaluation standards. China is seeking ways to start such evaluation by collaborating with international organizations. We intend to explore and establish proper evaluation system and evaluation standards, which are suitable to China and inconsistent with the development of China, and to help Chinese CE providers reach international criteria step by step.   

67

Molecular approaches to allergen standardization.  

Molecular approaches to allergen standardization include the development of purified natural or recombinant allergen standards whose structural and allergenic properties have been validated, in tandem with certified immunoassays for allergen measurement. Purified allergens can be used individually or incorporated into multiple allergen standards. Multicenter international collaborative studies are required to validate candidate allergen standards and immunoassays, as a prelude to being approved by regulatory agencies. Mass spectrometry is a sophisticated and powerful proteomics tool that is being developed for allergen analysis. Recent results using pollen allergens show that mass spectrometry can identify and measure specific allergens in a complex mixture and can provide precise information of the variability of natural allergen extracts. In future, the combined use of immunoassays and mass spectrometry will provide complete standardization of allergenic products. Molecular standardization will form the basis of new allergy diagnostics and therapeutics, as well as assessment of environmental exposure, and will improve the quality of treatment options for allergic patients. PMID:22740009

68

Trend of the bioceramics (for the international standardization); Baioseramikkusu no doko. Kokusai hyojunka nimukete  

The Ministry of International Trade and Industry Agency of Industrial Science and Technology would carry out development research of the standardization of test evaluation method of fine ceramics for the organism as research and development business of the international standardization promotion plan since this fiscal year. The fine ceramics becomes not possible material of lacking as alternative material of the organism. The public standard which appropriately evaluates the quality material in the other has not been established. JIS in the home of the result which there is Japan Fine Ceramics Association standard (test methods such as porosity and specific gravity, grain size, pore distribution, specific surface, Vickers hardness, crystal structure, bending strength, compressive strength, elastic modulus, fracture toughness, effluent of the bioceramics) JIS has not been instituted. It is present state that it becomes the Europe and America initiative artificial joint artificial bone expert committee TC-150 surgical internal burying agent ISO (ISO) and takes the one step delay. And, security of the reliability is necessary in order to fulfil the popularization in the market. The standardization must be hurried up. Research and development of test evaluation method of fine ceramics for the organism was carried out in order to attempt market expansion taking the reliability of fine ceramics material performance for the organism in our country as a sure thing, and standardizing into JIS and international standardization would be systematically advanced. Efforts would be made in fiscal 99 for research and development of evaluation method on abrasion resistance of artificial bone member subject, mechanical property such as strength degradation and biocompatibility. The technical committee of the industry-government-university from the specialist which consists in this inside is founded, and the deliberation for plan execution of this study development is got and will be effectively propelled. By lumping together, the development research will be entrusted in the foundation fine ceramics center. (translated by NEDO)

69

Nuclear Criticality Control and Safety of Plutonium-Uranium Fuel Mixtures Outside Reactors  

The ANSI/ANS 8.12 standard was first approved in July 1978. At that time, this edition was applicable to operations with plutonium-uranium oxide (MOX) fuel mixtures outside reactors and was limited to subcritical limits for homogeneous systems. The next major revision, ANSI/ANS-8.12-1987, included the addition of subcritical limits for heterogeneous systems. The standard was subsequently reaffirmed in February 1993. During late 1990s, substantial work was done by the ANS 8.12 Standard Working Group to re-examine the technical data presented in the standard using the latest codes and cross section sets. Calculations performed showed good agreement with the values published in the standard. This effort resulted in the reaffirmation of the standard in March 2002. The standard is currently in a maintenance mode. After 2002, activities included discussions to determine the future direction of the standard and to follow the MOX standard development by the International Standard Organization (ISO). In 2007, the Working Group decided to revise the standard to extend the areas of applicability by providing a wider range of subcritical data. The intent is to cover a wider domain of MOX fuel fabrication and operations. It was also decided to follow the ISO MOX standard specifications (related to MOX density and isotopics) and develop a new set of subcritical limits for homogeneous systems. This has resulted in the submittal (and subsequent approval) of the project initiation notification system form (PINS) in 2007.

70

[World Federation of Societies of Anaesthesiologists (WFSA) - security in anaesthesia - worldwide].  

In many countries of the world, standards of anaesthesiology are poor. Even the most modern equipment cannot be used properly without people who are able to work and deal with it. So education is a crucial requirement. Since 1955, the World Federation of Societies of Anaesthesiologists (WFSA) trains anaethesiologists worldwide to improve the standards of medicine in developing countries. The society works closely with WHO, ESA, FEEA and other international societies. Its aim: to make surgery safer throughout the world. PMID:18792867

71

Development of NO{sub x} aftertreatment for Renault diesel engines; Entwicklung der NO{sub x}-Nachbehandlung fuer Renault-Dieselmotoren  

The achievement of future emission standards for diesel engines requires the use of NO{sub x} aftertreatment systems, in addition to engine internal improvements. The NO{sub x} trap system, developed by Renault, enables heavy vehicles like minivans to reach future emission standards and maintain the diesel CO{sub 2} advantage. Equipped with the NO{sub x} trap, the Espace dCi 175 complies with Euro 5 and looks even further ahead with a technology that is ready for Euro 6. (orig.)

72

Smart grid communications standards  

Communications standards for smart grid programs were discussed. Standards are used to reduce integration costs and prevent single vendor lock-ins. Successful standards must have mature specifications and undergo certification and revision processes before being marketed and implemented. International standards associations use time-tested processes known to be both fair and open. Standards are now being developed for real time simulations, wide-area reliability, network optimization, and customer participation. Smart grid standards domains include wide area and field area networks, distributed resources, consumers, control centers, and commercial enterprises. Standards have been developed for control centres, power systems, distribution management interfaces, and common information models. Many transmission and distribution wide-area networks are becoming obsolete. Open standards have not yet been developed for many field area networks. Utilities are also concerned about standards for the integration of distributed generation resources. Common object models are needed, as well as stricter standards for transmission and distribution networks. More bandwidth is also required in order to fully merge IT with utility operations. An appendix of networking standards was included. tabs., figs.

73

Generating a foundation for Concurrent Engineering. Final report  

Both Concurrent Engineering and the Agile Enterprise require as a foundation the low cost, timely sharing of information. Described is a cost-effective way to generate this foundation from the product data International Standard 10303 (informally called STEP). Also described is a prototype implementation. AlliedSignal, Federal Manufacturing and Technologies (FM and T), was the first facility in the world to manufacture a mechanical part using the then draft international standard (DIS) ISO 10303 STEP. The Advanced Manufacturing Development System (AMDS) enabled this accomplishment.

74

SIMULTANEOUS DETERMINATION OF 14 QUINOLONES IN ROYAL JELLY BY LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY USING ANION-EXCHANGE SOLID-PHASE EXTRACTION  

A new method based on liquid chromatography-tandem mass spectrometry has been developed for simultaneous determination of 14 quinolones (QNs) residues, including ciprofloxacin, danofloxacin, difloxacin, enoxacin, enrofloxacin, flumequine, lomefloxacin, marbofloxacin, norfloxacin, orbifloxacin, ofloxacin, pipemidic acid, pefloxacin, and sarafloxacin in royal jelly. The proposed analytical procedure involves extraction of the QNs from samples by 0.1 M sodium hydroxide aqueous solution, a step for clean-up and preconcentration of the analytes by anion-exchange solid-phase extraction (SPE) and liquid chromatographic separation with mass spectrometric detection. Internal standard calibration was applied with norfloxacin-D5 as internal standard (I.S.). Satisfactory recovery (from 64% to 113...

75

It`s not easy being green: Environmental legal challenges and strategies for international oil and gas exploration and production  

International oil and gas E&P companies are being exposed to a steady proliferation of policies, laws, guidelines and other standards applicable to their activities. These are accompanied by expanded potential for legal and other liability. There are a number of treaties and other international agreements potentially relevant to F&P activities. National laws are the primary source of environmental law of concern to companies. However, guidelines developed by international governmental, financing, industry and other organizations are establishing standards to which companies may be held legally accountable. A number of key environmental issues and trends are influencing the development of environmental laws and generating areas of legal exposure for companies. Many basic company activities which involve layers are potentially affected. Companies can and should undertake a variety of activities to manage the environmental legal risks they face. Lawyers and negotiators for companies will play an essential role in developing and implementing such risk management programs.

76

Regulating food safety: the power of alignment and drive towards convergence  

Food safety is a complex policy domain: it involves a variety of stakeholders, touches upon a variety of issues and disciplines, and has an important international dimension. While countries are free to set their own standards, their policy autonomy in the process of regulating food safety is restricted by a number of factors. The EU and each member state are confronted with two aspects of compliance: the power of alignment with Codex standards, and the drive towards convergence with standards developed by trading partners. The importance attributed to the WTO and its reference organization, the Codex Alimentarius Commission, sheds light on the institutional constraints inherent in the international framework governing food safety while revealing the indirect power of alignment with intern...

77

Rapid determination of sodium in milk and milk products by capillary zone electrophoresis  

A capillary zone electrophoresis method for the determination of Na in milk and milk products was developed and compared with an International Organization for Standardization/International Dairy Federation standard method that is based on flame atomic absorption spectrometry. The adoption of a background electrolyte consisting of 10mM imidazole adjusted to pH 3.75 by the addition of oxalic acid allowed baseline separation of Na from other milk cations and from Li ion, which was adopted as an internal standard. Method validation was performed and the results for linearity, precision, limit of detection, limit of quantification, and recovery are presented. The procedure was tested on commercial milk samples differing in fat content (whole, semiskimmed, and skimmed) and processing conditions...

78

Preclinical pharmacokinetic analysis of armillarisin succinate ester in mouse plasma and tissues by LC-MS/MS.  

A liquid chromatography-tandem mass spectrometry (LC-MS/MS) has been developed and validated to determine the concentration of armillarisin succinate ester in mouse plasma and tissues, used for preclinical evaluation. Bavachin was employed as the internal standard. Separation was performed on a 3.5?µm Zorbax SB-C(18) column (30?×?2.1?mm), with a mobile phase consisting of methanol and aqueous 20?mm ammonium acetate. Both analyte and internal standard were determined using electrospray ionization and the MS data acquisition was via selected ion monitoring in negative scanning mode. Quantification was performed using the transitions m/z 333???233 and 323???221 for armillarisin succinate ester and internal standard, respectively. The method was validated with respect to linearity, accuracy, precision, recovery and stability. This assay has been successfully applied to a pharmacokinetic and tissue distribution study after intravenous injection of ASE in mouse in a dose of 10?mg/kg. Copyright © 2012 John Wiley & Sons, Ltd. PMID:22674750

79

Rapid determination of sodium in milk and milk products by capillary zone electrophoresis.  

A capillary zone electrophoresis method for the determination of Na in milk and milk products was developed and compared with an International Organization for Standardization/International Dairy Federation standard method that is based on flame atomic absorption spectrometry. The adoption of a background electrolyte consisting of 10 mM imidazole adjusted to pH 3.75 by the addition of oxalic acid allowed baseline separation of Na from other milk cations and from Li ion, which was adopted as an internal standard. Method validation was performed and the results for linearity, precision, limit of detection, limit of quantification, and recovery are presented. The procedure was tested on commercial milk samples differing in fat content (whole, semiskimmed, and skimmed) and processing conditions (pasteurization, UHT sterilization, and microfiltration). The reliability of the method was confirmed for different varieties of cheese and other milk products. The method enables the routine measurement of Na content by a rapid and accurate capillary zone electrophoresis procedure. PMID:22612924

80

Scoping Paper--Shaping a Career Development Culture: Quality Standards, Quality Practice, Quality Outcomes  

This project on national standards and accreditation of career practitioners is set against a background of unprecedented interest by governments nationally and internationally in the provision of career guidance services. Currently more is known about the policy and delivery of career guidance than at any other time in history. There is growing interest in the relationship between career guidance and public policy because the benefits of career guidance to individuals, society and the economy have been recognised. In this regard, strategic alliances are being formed between career guidance practitioners and policy makers in order that policy commitments relating to the provision of quality career services are enhanced. Such an alliance is evidenced in the collaboration between the Department of Education, Science and Training and the Career Industry Council of Australia on this project. This project constitutes a very necessary step in a move towards a quality industry. The purpose of this scoping paper is to: (1) identify current standards guiding career practitioners in Australia; (2) review international work on standards including examples of best practice and advise on how this work might be relevant to the development of national standards and accreditation in the Australian context; (3) be informed by outcomes of national workshops, forums, and conferences 2000-2004; (4) identify the current membership requirements of professional career associations and bodies both nationally and internationally; (5) assess how prior learning or qualifications might be recognised and developed to fit within and meet the requirements of the quality standards; and (6) identify the issues that need to be addressed in the development of national standards. To achieve this purpose, this paper is structured around four main sections--international quality standards, national quality standards, standards guiding Australian professions, and the Australian career industry. Following this a number of themes related to the development and implementation of quality standards will be elaborated. A number of issues relating to the development and implementation of quality standards and accreditation in the Australian career industry will then be raised. Appended are: (1) Glossary of terms; (2) Table of Comparative Competencies; (3) Entry-level Qualifications of Australian Career Practitioner Associations; (4) Standards of Australian Career Practitioner Associations; and (5) Comparison of Quality Standards Across Career Case Studies.

 
 
 
 
81

e-Research support services : responding to a challenge facing the South African research and information communities  

Opportunities for researchers to interact with their global counterparts have improved dramatically since the advent of the knowledge era. To ensure that South Africa continues to meet international standards, the South African national research and development strategy, published in 2002, invited r...

82

A new method to estimate risk and return of non-traded assets from cash flows: the case of private equity funds  

We develop a new methodology to estimate abnormal performance and risk exposure of non-traded assets from cash flows. Our methodology extends the standard internal rate of return approach to a dynamic setting. The small-sample properties are validated using a simulation study. We apply the method to...

83

Low-level waste forum meeting reports  

This paper provides highlights from the 1995 summer meeting of the Low Level radioactive Waste Forum. Topics included: new developments in state and compacts; federal waste management; DOE plans for Greater-Than-Class C waste management; mixed wastes; commercial mixed waste management; international export of rad wastes for disposal; scintillation cocktails; license termination; pending legislation; federal radiation protection standards.

84

Automatic steam traps. Classification  

This paper presents the ISO (International Standard Organization) Norm no. 6704, developed by the CTI (Italian Thermotechnical Committee), to regulate the classification of the main types (e.g., float, thermostatic and thermodynamic) of automatic steam traps in relation to the systems in which they operate.

85

Paper machine white water treatment in channel flow : integration of passive deaeration and selective flotation  

Gas removal from the papermaking process is currently a standard practice, whereas purification of the internal water circulation has become common only recently. Both unit processes have progressed greatly during recent decades and new concepts are constantly being developed. The aim of t...

86

Intended use of Reference Products & WHO International Standards/Reference Reagents in the development of Similar Biological Products (Biosimilars)  

Reference Products and WHO International Standards/Reference Reagents have roles to play in the development and characterization of similar biological products (SBPs). However, these roles are distinct and non-interchangeable. The uses of these materials and their limitations are considered in this paper.

87

Development and Validation of a HPLC Method to Determine Griseofulvin in Rat Plasma: Application to Pharmacokinetic Studies  

A simple, specific, sensitive, and rapid high performance liquid chromatography (HPLC) method for the determination of griseofulvin in small volumes of rat plasma was developed and validated using warfarin as an internal standard. Biological sample preparation involved simple extraction with acetoni...

88

Simple, Precise and Accurate HPLC Method of Analysis for Nevirapine Suspension from Human Plasma  

A selective and sensitive high performance liquid chromatography with UV detector (HPLC-UV) method was developed and validated from human plasma. Nevirapine and internal standard (IS) zidovudine were extracted from human plasma by liquid-liquid extraction process using methyl tert-butyl ether. The s...

89

Discriminatory Power and Reproducibility of Novel DNA Typing Methods for Mycobacterium tuberculosis Complex Strains  

In recent years various novel DNA typing methods have been developed which are faster and easier to perform than the current internationally standardized IS6110 restriction fragment length polymorphism typing method. However, there has been no overview of the utility of these novel typing methods, a...

90

Process Improvement and Capability Determination in Software, Systems Engineering and Service management  

The SPICE Project was formed in 1993 to support the development of an international standard for software process assessment. The work of the project has led eventually to the finalisation of ISO/IEC 15504 - Process Assessment, and its complete publication represented a climax for the work of the pr...

91

Marine fuels  

This book presents the papers given at a conference on the use of petroleum products as marine fuels. Topics considered at the conference included international standards, US marine fuel oil availability, the design of diesel engines, the combustion properties of liquid fuels, the development of evaluation methods for determining the stability of marine fuels, and controlling the compatibility of residual fuel oils.

92

In times of Integration : Can there only be one?  

From late last century there has been a great development of international standards and tools on environment, sustainability and corporate responsibility issues. This has been along with the globalization of economy and politics, as well as a shift in the social responsibilities of the private vis-...

93

RAPID SAMPLE PREPARATION METHOD FOR LC-MS/MS OR GC-MS ANALYSIS FOR ACRYLAMIDE IN VARIOUS FOOD MATRICES  

A fast and easy sample preparation procedure for analysis of acrylamide in various food matrices was developed and optimized. In its first step, deuterated acrylamide internal standard is added to 1 g of homogenized sample together with 5 mL hexane, 10 mL water, 10 mL acetonitrile, 4 g MgSO4 and 0....

94

Determination of Actarit from Human Plasma for Bioequivalence Studies  

An analytical method based on high-performance liquid chromatography with ultraviolet detection (245 nm) was developed for the determination of actarit in human plasma. Coumarin was used as an internal standard. Chromatographic separation was achieved with a C8 column using a mobile phase of methano...

95

Qualification plan for the Genmod-PC computer program  

Genmod-PC is an internal dosimetry code that uses Microsoft Windows operating system, and that currently calculates radionuclide doses and intakes for an adult male. This report provides a plan for specifying the quality assurance measures that conform to the recommendations of the Canadian Standards Association, as well as AECL procedural requirements for a legacy computer program developed at AECL. (author)

96

Implications of the agreement on internal trade for chiropractic regulatory bodies in Canada  

The Agreement on Internal Trade (“AIT”) is an agreement between the federal, provincial and territorial governments signed by the First Ministers on July 18, 1994. AIT is relevant to the mandate of chiropractic regulatory bodies to develop standards of admission to the profession, conduct examinatio...

97

Liquid Chromatographic Determination of Flavoxate HCl in Pharmaceutical Formulation  

The objective of the study was to develop a high performance liquid chromatography (HPLC) method using ultra violet (UV) detection for the determination of flavoxate HCl in bulk and solid dosage forms by using ibuprofen as the internal standard. Eclipse C18 column (150 mm × 4.6 mm, 5 ?m) was used as...

98

Mass Spectrometric Separation and Determination of N1, N12-Diacetylspermine in the Urine of Cancer Patients  

An ionspray ionization mass-spectrometric method for the determination of N1,N12-diacetylspermine (Ac2Spm) was developed using 15N-labeled Ac2Spm as the internal standard. Concentrations of Ac2Spm in the urine obtained from 17 cancer patients measured by the present method correlated well with those measured by ELISA, showing the usefulness of the two methods.   

99

Analysis of the uncertainties in the IAEA/WHO TLD postal dose audit programme  

The International Atomic Energy Agency (IAEA) and the World Health Organisation (WHO) operate the IAEA/WHO TLD postal dose audit programme. The purpose of the programme is to verify the beam calibration in radiotherapy centres in developing countries and to check the Secondary Standards Dosimetry...

100

The IAEA’s activities on radiation protection in interventional cardiology  

The International Atomic Energy Agency (IAEA) under its mandate of developing and applying standards of radiation safety has initiated a number of activities in recent years on radiation protection in interventional cardiology. These activities are implemented through four mechanisms, namely trainin...

 
 
 
 
101

Direct solid analysis of powdered tungsten carbide hardmetal precursors by laser-induced argon spark ablation with inductively coupled plasma atomic emission spectrometry.  

The potential of the laser-induced argon spark atomizer (LINA-Spark atomizer) coupled with ICP-AES as a convenient device for direct analysis of WC/Co powdered precursors of sintered hardmetals was studied. The samples were presented for the ablation as pressed pellets prepared by mixing with powdered silver binder containing GeO2 as internal standard. The pellets were ablated with the aid of a Q-switched Nd:YAG laser (1064 nm) focused 16 mm behind the target surface with a resulting estimated power density of 5 GW cm(-2). Laser ablation ICP-AES signals were studied as a function of ablation time, and the duration of time prior to measurement (pre-ablation time) which was necessary to obtain reliable results was about 40 s. Linear calibration plots were obtained up to 10% (m/m) Ti, 9% Ta and 3.5% Nb both without internal standardization and by using germanium as an added internal standard or tungsten as a contained internal standard. The relative uncertainty at the centroid of the calibration line was in the range from +/- 6% to +/- 11% for Nb, Ta and Ti both with and without internal standardisation by Ge. A higher spread of points about the regression was observed for cobalt for which the relative uncertainty at the centroid was in the range from +/- 9% to +/- 14%. Repeatability of results was improved by the use of both Ge and W internal standards. The lowest determinable quantities calculated for calibration plots were 0.060% Co, 0.010% Nb, 0.16% Ta and 0.030% Ti with internal standardization by Ge. The LA-ICP-AES analyses of real samples led to good agreement with the results obtained by solution-based ICP determination with a relative bias not exceeding 10%. The elimination of the dissolution procedure of powdered tungsten (Nb, Ta, Ti) carbide is the principal advantage of the developed LA-ICP-AES method. PMID:14564441

102

The role of the World Organisation for Animal Health (OIE) to facilitate the international trade in animals and animal products.  

The international trade in animals and animal products has become a sensitive issue for both developed and developing countries by posing an important risk for the international spread of animal and human pathogens whilst at the same time being an essential activity to ensure world-wide food security and food safety. The OIE has since its founding in 1924, applied a democratic and transparent decision-making process to continuously develop and review international standards for animal health and zoonoses to facilitate trade in animals and animal products. The role of the OIE is also mandated by the World Trade Organization (WTO) as international reference point for standards related to animal health. In support of its overall objective of promoting animal health world-wide, the OIE has also launched several other initiatives such as the improvement of the governance of veterinary services within its member countries and territories and to enhance the availability of diagnostic and scientific expertise on a more even global geographical distribution. Several trade facilitating concepts such as country, zonal and compartment freedom from disease as well the trade in disease free commodities has been introduced to enhance the trade in animals and animal products for all its members including those from developing and transitional countries who are still in the process of enhancing to full compliance with international sanitary standards. PMID:19967940

103

Overview of PV balance-of-systems technology: Experience and guidelines for utility ties in the United States of America  

The U.S. National Photovoltaic Program began in 1975 by supporting the development of terrestrial PV modules and hardware associated with grid-connected PV systems. Early PV-system demonstration programs were also supported and cost shared by the U.S. Department of Energy (DOE). A wide variety of PV systems were deployed, usually with utility participation. The early demonstration projects provided, and continue to provide, valuable PV system experience to utilities, designers and suppliers. As a result of experience gained, several important milestones in codes and standards pertaining to the design, installation and operation of photovoltaic (PV) systems have been completed. These code and standard activities were conducted through collaboration of participants from all sectors of the PV industry, utilities and the US DOE National Photovoltaic Program. Codes and standards that have been proposed, written, or modified include changes and additions for the 1999 National Electric Code{reg_sign} (NEC{reg_sign}), standards for fire and personnel safety, system testing, field acceptance, component qualification, and utility interconnection. Project authorization requests with the Institute of Electrical and Electronic Engineers (IEEE) have resulted in standards for component qualification and were further adapted for standards used to list PV modules and balance-of-system components. Industry collaboration with Underwriter Laboratories, Inc., with the American Society for Testing and Materials, and through critical input and review for international standards with the International Electrotechnical Commission have resulted in new and revised domestic and international standards for PV applications. Activities related to work on codes and standards through the International Energy Agency are also being supported by the PV industry and the US DOE. The paper shows relationships between activities in standards writing.

104

A NEW APPROACH TO DEVELOPMENT OF VOLUNTARY DECOMISSIONING STANDARDS  

The purpose of the Decontamination, Decommissioning, and Reutilization (DDR) Division of the American Nuclear Society (ANS) is to advance the technology of decontamination, decommissioning, and reutilization of nuclear and former nuclear installations, materials, facilities, and sites [1]. This includes sharing collective decommissioning experiences and lessons learned with others in the industry. An integral part of the work of the DDR Division is the preparation of voluntary decommissioning standards through its recently re-established DDR Standards Committee. This Committee intends to support development of various standards with other divisions of the ANS. The Committee also intends to participate with external organizations to disseminate information and lessons learned regarding decontamination activities, and participate in the development of voluntary decommissioning standards. External organizations, such as ASTM International, are involved in the development of consensus standards for nuclear decommissioning work. This paper describes the work of the DDR Standards Committee on a new co-operative initiative with ASTM International to develop voluntary consensus standards for nuclear decommissioning work.

105

Criteria and indicators for sustainable forest fuel production and harvesting: A review of current standards for sustainable forest management  

Forest biomass is increasingly being considered as a source of sustainable energy. It is crucial, however, that this biomass be grown and harvested in a sustainable manner. International processes and certification systems have been developed to ensure sustainable forest management (SFM) in general, but it is important to consider if they adequately address specific impacts of intensified production and harvesting methods related to forest fuels. To explore how existing SFM frameworks address sustainable forest fuel production, criteria and indicators (C&I) from 10 different international processes and organizations and 157 international, national and sub-national forest management certification standards under the Forest Stewardship Council (FSC) and the Programme for the Endorsement of F...

106

Direct puncture of the highest cervical segment of the internal carotid artery for treatment of an iatrogenic carotid cavernous fistula in a patient with Ehlers-Danlos syndrome.  

A case of an iatrogenic direct carotid cavernous fistula in a patient with a history of Ehlers-Danlos syndrome and multiple aneurysms is reported. The fistula developed after unsuccessful surgical thrombectomy and revision of an occluded interposition graft inserted to treat a right internal carotid artery aneurysm. Direct puncture of the right internal carotid artery at the level of the skull base was performed to close the fistula. This case shows that direct puncture at the highest cervical segment of the internal carotid artery is another option for treatment of a direct carotid cavernous fistula when a standard transarterial or transvenous approach is not feasible. PMID:22131435

107

Development of quantitative NMR method with internal standard for the standard solutions of paralytic shellfish toxins and characterisation of gonyautoxin-5 and gonyautoxin-6  

The chemical analysis of paralytic shellfish toxins (PSTs) requires standard solutions with accurate concentration. The mouse toxicity in each toxin is also essential knowledge for the introduction of chemical analysis as an alternative method to mouse bioassay (MBA) in routine monitoring of shellfish. In this study, we developed the quantitative analysis of PSTs by nuclear magnetic resonance (NMR), using tert-butanol as an internal standard. Only proton signals with longitudinal relaxation time (T1) of less than 2.5 s, including the internal standard, were used for quantitation of toxins. Our method showed good precision (<3%) and accuracy (slope: 1.0038, R2: 1.0000). The limit of quantitation (LOQ) at 5% relative standard deviation (RSD) was calculated to be 0.16 mM, which corresponded t...

108

Implementation of a standards-based anaesthesia record compliant with the health level 7 (HL7) clinical document architecture (CDA).  

With the increasing use of anaesthesia information management systems (AIMS) there is the opportunity for different institutions to aggregate and share information both nationally and internationally. Potential uses of such aggregated data include outcomes research, benchmarking and improvement in clinical practice and patient safety. However, these goals can only be achieved if data contained in records from different sources are truly comparable and there is semantic inter-operability. This paper describes the development of a standard terminology for anaesthesia and also a Domain Analysis Model and implementation guide to facilitate a standard representation of AIMS records as extensible markup language documents that are compliant with the Health Level 7 Version 3 clinical document architecture. A representation of vital signs that is compliant with the International Standards Organization 11073 standard is also discussed. PMID:22614336

109

Development of primary standard for hydrocarbon flow and traceability system of measurement in Japan  

It is of importance to establish the hydrocarbon flow standard which acts as the basis for vast dealings and taxation for hydrocarbons, enforcement of the policy on energy savings and high quality management of industries. As a result of investigation into calibration methods, reliability, and effectiveness, the specification of the national primary standard and the traceability system for hydrocarbon flow in Japan was designed. We took the technical initiative in establishing the traceability system using JCSS (Japan Calibration Service System) as basis of the national primary standard in the limited region of flow rates and various kinds of liquids. The national primary standard of high accuracy and safety has been developed. This project was evaluated through verification of international consistency by way of international key comparisons.   

110

Fiscal 1997 report on the results of the international standardization R and D. Basic technology of color image management; 1997 nendo seika hokokusho kokusai hyojun soseigata kenkyu kaihatsu. Color gazo management kiban gijutsu  

In relation to the color image management, the basic technology was researched/developed for the purpose of creating the standards in Japan. As to the standardization of the method to regulate color space, various color spaces were studied from a visual aspect. In the study and trial development of light sources for color reproduction/evaluation, developed was D 50, a common use light source using fluorescent lump. Concerning the color standard input/output interface, proposed was a new chromatic adaptation model, S-LMS, for correction of chromatic adaptation. In the development of standard data on high accurate/fine images, made were high-quality image data which can be a candidate to be proposed from Japan to ISO/TC130 doing activities for the international standardization of images. Besides, the following development/R and D were made: spectral characteristic database for evaluating color reproducing ability of the color image input device, technology to evaluate color reproducing ability of digital camera, technology to evaluate color reproducing ability of color scanner, standard data for the diversification of international information exchanges, etc. 167 refs., 268 figs., 86 tabs.

111

Interim test methods and procedures for determining the performance of small photovoltaic systems  

This document provides test methods and procedures for determining the performance of small stand-alone and utility-grid connected PV systems. The procedures in this document provide a common approach for evaluating whether a given PV system is suitable to perform the function it was designed and manufactured to accomplish and meet the application load. This test document fills a testing void and provides the catalyst and focus for establishing the technical foundation and bridging the institutional barriers needed to reduce uncertainty that a system`s performance will be what its designers and builders claim. The need for this document was recently made more apparent with the initiation of a PV Global Approval Program (PVGAP) at the international level and is in response to concerns that PV systems being fielded must meet performance standards and that these standards include system-level performance type tests. The title of these test procedures is prefaced with the word interim because experience in using the procedures is needed before a consensus standard is developed and accepted by the PV community through its activities with the IEEE Standards Coordinating Committee 21 (SCC21) and International Electrotechnical Commission Technical Committee 82 (IEC TC82) national and international standards-making bodies. Both entities have initiated projects to develop test standards and will need the technical basis and validation of test procedures such as those presented in this document before a consensus is achieved by the PV community.

112

International Energy: Subject Thesaurus. Revision 1  

The International Energy Agency: Subject Thesaurus contains the standard vocabulary of indexing terms (descriptors) developed and structured to build and maintain energy information databases. Involved in this cooperative task are (1) the technical staff of the USDOE Office of Scientific and Technical Information (OSTI) in cooperation with the member countries of the International Energy Agency`s Energy Technology Data Exchange (ETDE) and (2) the International Atomic Energy Agency`s International Nuclear Information System (INIS) staff representing the more than 100 countries and organizations that record and index information for the international nuclear information community. ETDE member countries are also members of INIS. Nuclear information prepared for INIS by ETDE member countries is included in the ETDE Energy Database, which contains the online equivalent of the printed INIS Atomindex. Indexing terminology is therefore cooperatively standardized for use in both information systems. This structured vocabulary reflects thscope of international energy research, development, and technological programs. The terminology of this thesaurus aids in subject searching on commercial systems, such as ``Energy Science & Technology`` by DIALOG Information Services, ``Energy`` by STN International and the ``ETDE Energy Database`` by SilverPlatter. It is also the thesaurus for the Integrated Technical Information System (ITIS) online databases of the US Department of Energy.

113

Standard XRF analytical methods for the mining, mineral processing and metallurgy industry  

Various industries throughout the world require Standard methods for trade of products and referee analysis. Over the past 20-30 years, a number of wet-chemical Standard methods have been developed and are in use. Due to the large number of elements required for analysis in most products, XRF methods have become attractive as techniques to handle many elements simultaneously with a simple single sample preparation. Despite XRF being in daily use in many industries as an {open_quote}in-house{close_quote} method, there are relatively few National or International Standard XRF methods. For some years, Norrish and his associates (CSIRO Division of Soils, Adelaide, Australia) have been involved in the preparation of Australian and International Standard XRF methods based on borate fusions. A method for the analysis of nine elements in iron ores has recently been published by the International Standards Organization (ISO 9516, 1992). This method has been expanded to include iron and trace elements, some twenty elements in all, and will be tested on an international scale in 1995. A method document for the analysis of twenty elements in titaniferous sands has been drafted and submitted to Standards Australia for public review (DR 93129, 1993) prior to publication as an Australian Standard method. In addition, a test program has been completed for the analysis of fourteen elements in zircon sands and the method document is currently being drafted. This paper will outline the general approach and techniques of the Standard methods, using the methods developed for the Australian mineral sands industry for the analysis of titaniferous mineral sands (ilmenite and rutile) and for zircon sands as examples. 3 refs., 9 tabs.

114

National electrical standards supporting internationalcompetition of Japanese manufacturing industries  

A capacitor or a condenser is one of the most basic electrical devices and is used in various electrical equipments. Recently the electrical equipment industry has been requesting the quality of capacitors to be compatible with international standards; among other things, it is strongly demanded that the traceability of a capacitance standard should be consistent with the national standards. To respond to this need from the industry, we have developed a new national standard of capacitance based on the quantized Hall resistance and also established its traceability system in cooperation with the accredited calibration businesses. A remote calibration system of capacitance has also been developed to disseminate the standard quickly and to reduce calibration costs.   

115

7075-T6 and 2024-T351 Aluminum Alloy Fatigue Crack Growth Rate Data  

Experimental test procedures for the development of fatigue crack growth rate data has been standardized by the American Society for Testing and Materials. Over the past 30 years several gradual changes have been made to the standard without rigorous assessment of the affect these changes have on the precision or variability of the data generated. Therefore, the ASTM committee on fatigue crack growth has initiated an international round robin test program to assess the precision and variability of test results generated using the standard E647-00. Crack growth rate data presented in this report, in support of the ASTM roundrobin, shows excellent precision and repeatability.

116

[The 2008 international standards for a safe practice of anesthesia].  

This is an update of the standards developed by the International Task Force on Anesthesia Safety, which were adopted by the World Federation of Societies of Anesthesiologists (WFSA) on 13 June 1992. These standards incorporate and elaborate upon the core components of the Safe Anesthesia part of the 2008 World Health Organization's World Alliance for Patient Safety "Safe Surgery Saves Lives" global initiative. These WFSA standards are intended to provide guidance and assistance to anesthesia professionals, their professional societies, hospital and facility administrators, and governments for improving and maintaining the quality and safety of anesthesia care. PMID:20101790

117

Representing fixed-term workers: the anatomy of a trade union campaign  

Purpose - Drawing on literature that examines trade union representation of "non-standard" workers, this paper aims to analyse the attempts of the Association of University Teachers (AUT) to integrate the interests of contract research staff (CRS) employed on fixed-term contracts between 1974 and 2002. The paper examines the union campaign under five areas identified in the literature as important to the development of representation of non-standard workers: trade union orientation to non-standard workers; recruitment; participation; collective bargaining; extending representation beyond collective bargaining. Design/methodology/approach - The main sources of data are drawn from analyses of union documentation, including internal memoranda and reports dating back to 1974, which chart the a...

118

Geography Markup Language  

Geography Markup Language (GML) is an XML application that provides a standard way to represent geographic information. GML is developed and maintained by the Open Geospatial Consortium (OGC), which is an international consortium consisting of more than 250 members from industry, government, and university departments. Many of the conceptual models described in the ISO 19100 series of geomatics standards have been implemented in GML, and it is itself en route to becoming an ISO Standard (TC/211 CD 19136). An overview of GML together with its implications for the geospatial web is given in this paper.   

119

HIV prevention research and global inequality: steps towards improved standards of care.  

Intensification of poverty and degradation of health infrastructure over recent decades in countries most affected by HIV/AIDS present formidable challenges to clinical research. This paper addresses the overall standard of health care (SOC) that should be provided to research participants in developing countries, rather than the narrow definition of SOC that has characterised the international debate on standards of health care. It argues that contributing to sustainable improvements in health by progressively ratcheting the standard of care upwards for research participants and their communities is an ethical obligation of those in resource-rich countries who sponsor and implement research in poorer ones. PMID:15634752

120

Current Status of VO Compliant Data Service in Japanese Virtual Observatory  

In these years, standards to build a Virtual Observatory (VO) data service have been established with the efforts in the International Virtual Observatory Alliance (IVOA). We applied these newly established standards (SSAP, TAP) to our VO service toolkit which was developed to implement earlier VO standards SIAP and (deprecated) SkyNode. The toolkit can be easily installed and provides a GUI interface to construct and manage VO service. In this paper, we describes the architecture of our toolkit and how it is used to start hosting VO service.

 
 
 
 
121

Development of a Combined Standard Additions/Internal Standards Method to Quantify Residual PEG in Ethoxylated Surfactants by MALDI TOFMS  

Measuring the residual polyethylene glycol (PEG) in polyethylene oxide (PEO)-based surfactants is important to fully understanding the performance of these materials. Traditional methods of quantitating PEG in PEO-based surfactants can be time-consuming and struggle with low amounts or overlapping molecular mass distributions. This paper describes a matrix-assisted laser desorption/ionization (MALDI) mass spectrometry method developed to quantitate residual PEG in a series of ethoxylated surfactants. The technique addresses the difficulties faced in doing quantitative MALDI experiments by utilizing both internal standard and standard additions protocols. The method produces excellent straight line standard addition plots, and the quantitative results are verified using both a constructed s...

122

Taking the Lead in Science Education: Forging Next-Generation Science Standards. International Science Benchmarking Report  

In response to concerns over the need for a scientifically literate workforce, increasing the STEM pipeline, and aging science standards documents, the scientific and science education communities are embarking on the development of a new conceptual framework for science, led by the National Research Council (NRC), and aligned next generation science standards, led by Achieve. The American Association for the Advancement of Science (AAAS) and the National Science Teachers Association (NSTA) are also key partners in this effort. Leaders have called for U.S. standards to be internationally benchmarked--reflective of the expectations that other leading nations have set for their students. To that end, Achieve examined 10 sets of international standards with the intent of informing the development of both the conceptual framework and new U.S. science standards. Achieve selected countries based on their strong performance on international assessments and/or their economic, political, or cultural importance to the United States. The overall goal of Achieve's study on international standards is to inform the development of the NRC framework and next-generation science standards. Through a quantitative analysis of international standards, Achieve's reviewers discovered four key findings: (1) All countries require participation in integrated science instruction through Lower Secondary and seven of 10 countries continue that instruction through Grade 10, providing a strong foundation in scientific literacy; (2) Physical science content standards (physics and chemistry content taken together) receive far more attention in lower primary through lower secondary. Other countries dedicate the greatest proportion of their standards to biology and physics content and the least to Earth and space science; (3) Other countries' standards focus life science instruction strongly on human biology, and relationships among living things in a way that highlights the personal and social significance of life science for students and citizens. However, in the U.S., virtually all states also have a requirement for health and physical education from lower primary to lower secondary which could explain the difference in focus; and (4) Cross-cutting content common to all of the sciences such as the nature of science, nature of technology and engineering receives considerable attention. Inquiry skills in Primary are stressed more than in Lower Secondary. However, advanced inquiry skills receive increasing attention in Lower Secondary. (Contains 3 charts, 6 figures, 15 tables, and 62 footnotes.) [For the accompanying appendix, see ED512107.

123

A model of clearance rate regulation in mussels  

Clearance rate regulation has been modelled as an instantaneous response to food availability, independent of the internal state of the animals. This view is incompatible with latent effects during ontogeny and phenotypic flexibility in clearance rate. Internal-state regulation of clearance rate is required to account for these patterns. Here I develop a model of internal-state based regulation of clearance rate. External factors such as suspended sediments are included in the model. To assess the relative merits of instantaneous regulation and internal-state regulation, I modelled blue mussel clearance rate and growth using a DEB model. In the usual standard feeding module, feeding is governed by a Holling's Type II response to food concentration. In the internal-state feeding module, gil...

124

An iterative process of global quality improvement: the International Standards for a Safe Practice of Anesthesia 2010.  

PURPOSE: To enhance patient safety through contemporaneous and comprehensive standards for a safe practice of anesthesia that augment, enhance, and support similar standards already published by various countries and that provide a resource for countries that have yet to formulate such standards. STANDARDS DEVELOPMENT: The Safe Anesthesia Working Group of the World Health Organization's "Safe Surgery Saves Lives" global initiative updated the 1992 International Standards for the Safe Practice of Anaesthesia (Standards) through an iterative process of literature review, consultation, debate, drafting, and refinement. These Standards address, in detail, the organization, support, practices, and infrastructure for anesthesia care. The Standards are grounded in the fundamental principle of safety in anesthesia, i.e., the continuous presence of an appropriately trained, vigilant anesthesia professional. In effect, the use of pulse oximetry during anesthesia is now considered mandatory, with acknowledgement that compromise may be unavoidable in emergencies. At the World Congress of Anaesthesiologists in 2008, drafts were presented for comment, further refinements were made, and the Revised Standards were adopted by the World Federation of Societies of Anaesthesiologists (WFSA). These Revised Standards were posted on the WFSA website for further feedback, and minor revisions followed. The International Standards for a Safe Practice of Anesthesia 2010 were endorsed by the Executive Committee of the WFSA in March 2010. Ongoing periodic revision is planned. CONCLUSION: While they are universally applicable, the 2010 Standards primarily target lesser-resourced areas. They are designed particularly for regions that have yet to formulate or adopt their own standards so as to promote optimum patient outcomes in every anesthetizing location in the world. PMID:20857255

125

NAFTA takings update the Glamis decision  

In the first mineral takings decision under NAFTA, notwithstanding expenditures of $15 million by the developer, the international tribunal decided there was no taking. The tribunal concluded that a less profitable alternative mineral extraction process was available and the mineral property retained substantial value. In regard to the customary international law minimum standard of treatment the tribunal concluded that the Neer v Mexico standard adopted in 1926 remains central in determining whether NAFTA Article 1105 has been breached. With regard to environmental concerns, Article 1114 appears to have had an indirect, interpretive influence on the decision. In light of the strict standard adopted by the tribunal in the Glamis decision, we submit that, in the future, mineral developers i...

126

Steady march of atomic time  

The use of atomic clocks as frequency standards for maintaining accurate international time-keeping, is examined. The choice of the cesium atom to provide the frequency standard, using the very precise changes between two energy states of the atom, the provision of international calibration standards, and the international coordination of time scales, are discussed.

127

Calculating the heat transfer coefficient of frame profiles with internal cavities  

Determining the energy performance of windows requires detailed knowledge of the thermal properties of their different elements. A series of standards and guidelines exist in this area. The thermal properties of the frame can be determined either by detailed two-dimensional numerical methods or by measurements in accordance to European or international standards. Comparing measured and calculated heat transfer coefficients for two typical frame profiles with cavities shows considerable differences. This investigation considers two typical frame profiles in aluminium and PVC with internal cavities. The heat transfer coefficient is determined by two-dimensional numerical calculations and by measurements. Calculations are performed in Therm (LBNL (2001)), which is developed at Lawrence Berkeley National Laboratory, USA. The calculations are performed in accordance with the future European standards and measurements have been performed at two German research institutes. The internal cavities have a large influence on the overall thermal performance of the frame profiles and the investigation shows that the applied method for modelling the heat transfer by radiation exchange in the internal cavities of the profiles is critical. The simple radiation model described in the pre European standard (prEN ISO 10077-2) does not yield valid results compared to measured values. Applying a more detailed, viewfactor based, grey surfaces enclosure model as described in the ISO standard (ISO/DIS 15099) gives a better correspondence between measured and calculated values. Hence, when determining the heat transfer coefficient of frame profiles with internal cavities by calculations, it is necessary to apply a more detailed radiation exchange model than described in the prEN ISO 10077-2 standard. The ISO-standard offers such an alternative.

128

1994 DOE Technical Standards Program Workshop: Proceedings  

The DOE Technical Standards Program has been structured to provide guidance and assistance for the development, adoption, and use of voluntary standards within the Department. OMB Circular A-119, ``Federal Participation in the Development and Use of Voluntary Standards`` establishes the policy to be followed in working with voluntary standards bodies, and in adopting and using voluntary standards whenever feasible. The DOE Technical Standards Program is consistent with this policy and is dedicated to the task of promoting its implementation. The theme of this year`s workshop is ``Standards Initiatives in Environmental Management fostering the development and use of industry standards for safe, environmentally responsible operations.`` The objective of the workshop is to increase the participant`s awareness of the standardization activities taking place nationally and internationally and the impact of these activities on their efforts, and to facilitate the exchange of experiences, processes, and tools for implementing the program. Workshop sessions will include presentations by industry and Government notables in the environment, safety, and health arena with ample opportunity for everyone to ask questions and share experiences. There will be a breakout session which will concentrate on resolution of issues arising from the implementation of the DOE Technical Standards Program and a plenary session to discuss the plans developed by the breakout groups. Many organizations provide services and products which support the development, processing, distribution, and retrieval of standards. Those organizations listed at the end of the agenda will have exhibits available for your perusal throughout the workshop. Last year`s workshop was very successful in stimulating an understanding of an interest in the standards program. This year, we hope to build on that success and provide an environment for the synergism of ideas to enhance the program and advance its implementation.

129

Development of examination technology for detecting defects in spent fuel rods using eddy current  

A program for data acquisition and analysis of eddy currents on fabricated standard specimen was developed. Eddy current examination technology enabled to detect 0.06mm in depth of external defects in standard specimen, 0.12mm in depth of internal defects in standard specimen and 0.20mm in diameter of through hole defects in standard specimen using differential encircling probe was developed. The impedance amplitude of eddy currents increased as defect size grew and impedance phases of eddy currents on defect types were distinguishable. The defect locations and defect types of spent fuel rods were detected by applying the developed technology of eddy current examinations to spent fuel rods and it was reconfirmed that the results of eddy current examinations on the defects in spent fuel rods was in good agreement with microscopic photographs on the defects in spent fuel rods. (author). 42 refs., 22 figs., 1 tab.

130

Development and application of a calibration technique for laser ablation - ICP - MS  

Laser Ablation - Inductively Coupled Plasma - Mass Spectrometry (LA-ICP-MS) is a powerful analytical technique for the direct elemental analysis of solid samples, with spatial resolution down to a few microns. However, calibration remains the limiting factor in obtaining quantitative analysis by LA-ICP-MS for a wide range of sample types. No universal method exists as yet and the ones that are currently used tend to employ matrix-matched solid standards. Matrix-matched solid standards are not available for many types of sample, such as polymers, biological materials, fluid inclusions, etc. The need for a universal method of calibration that involves standards that are easy to prepare and suitable for any type of sample is required. Additional to matrix-matching, internal standards are widely used in LA-ICP-MS for quantitative analyses. The internal standard compensates for the different ablation yields from the sample and the standard and for the laser shot-to-shot variation. Given that the use of an internal standard is required to obtain reliable results, the need for matrix-matching might be regarded as questionable. This project has focused on the development and application of a new method of calibration for LA-ICP-MS. It involves the use of aqueous standards whose absorption characteristics are modified by the addition of a chromophore to the solution. Additives were selected for ablation with KrF excimer, and Nd:YAG lasers. The influence of the additive concentration on the ablation yield was investigated for different laser energies. Response curves were obtained showing that as the additive concentration was increased, less energy was required to ablate the modified standard solutions efficiently. A general procedure was then defined for the preparation and use of the modified standard solutions for a given sample. The new method of calibration was used for the quantitative analysis of different sample types: low density polyethylene (LDPE), polyketone (PK), polyethylene thin film as well as gels contained in the thin film, and stainless steel. (author)

131

Nondestructive assessment of internal quality of Gannan navel orange by photodiode array spectrometer  

The photodiode array (PDA) spectrometer combined with partial least square (PLS) was developed to rapid measure the internal quality indices of Gannan navel orange nondestructively in the wavelength range of 550-950nm. The original spectra were processed by standard normal variate (SNV) and Savitzky-Golay (SG) smooth method. The optimal models of internal quality indices were determined after different spectral windows chosen. The optimal model of soluble solids content (SSC), total acidity (TA) and ratio of them were developed with RMSECV = 0.5118Brix%, 0.0856% and 2.0617 by PLS method, respectively. The optimal spectral windows were 700-950nm, 600-750nm and 600-950nm for measuring internal indices nondestructively by PDA. The results illustrated that PDA with PLS method were a rapid tool to measure the internal quality indices of Gannan navel orange nondestructively.

132

International research collaboration in maritime health  

The new ILO-2006-convention and the EU Commission's strategic objectives for the EU maritime transport policy 2008-2018, mentions the necessity of a modern health and safety system for maritime transportation. However, there is no specific strategy for the development of maritime health and safety. The area is regulated by international standards based on international research-based knowledge on health and safety. Moreover, many of the world's seafarers come from developing countries with specific disease problems like HIV and no possibility of independent maritime health research. The international maritime health research is sparse, and an increase in such research is necessary to help benefit needed shipping as a highly globalized industry. This paper presents an example of such research, accompanied by a discussion of methods and opportunities to increase international maritime health research.

133

Transitions of Care Consensus Policy Statement: American College of Physicians, Society of General Internal Medicine, Society of Hospital Medicine, American Geriatrics Society, American College of Emergency Physicians, and Society for Academic Emergency Medicine  

The American College of Physicians, Society of Hospital Medicine, and Society of General Internal Medicine convened a multi-stakeholder consensus conference in July 2007 to address the quality gaps in the transitions between inpatient and outpatient settings and to develop consensus standards for these transitions. Over 30 organizations sent representatives to the Transitions of Care Consensus Conference. Participating organizations included medical specialty societies from internal medicine as well as family medicine and pediatrics, governmental agencies such as the Agency for Healthcare Research and Quality and the Centers for Medicare and Medicaid Services, performance measure developers such as the National Committee for Quality Assurance and the American Medical Association Physician ...

134

Measurement of luminous reflectivity of coal in Czechoslovakia in accordance with international standards  

Discusses in general terms development of international standards for determining luminous reflectivity of vitrinites in bituminous coal and anthracite and development of systems for assessing coal quality according to degree of coalification. Describes history of applied coal petrology in Czechoslovakia and use of vitrinite reflectivity for coal ranking, with reference to equipping laboratories with microphotometric apparatus and providing them with experienced staff. Concludes that more petrological laboratories capable of microphotometry are required in Czechoslovakia, particularly in the Ostrava-Karvina coalfield. 6 refs.

135

ChOrDa: a methodology for the modeling of business processes with BPMN  

In this paper we present a modeling methodology for BPMN, the standard notation for the representation of business processes. Our methodology simplifies the development of collaborative BPMN diagrams, enabling the automated creation of skeleton process diagrams representing complex choreographies. To evaluate and tune the methodology, we have developed a tool supporting it, that we apply to the modeling of an international patenting process as a working example.

136

Assuring food safety: the complementary tasks and standards of the World Organisation for Animal Health and the Codex Alimentarius Commission.  

The Agreement on the Application of Sanitary and Phytosanitary Measures of the World Trade Organization specifically recognises the international standards developed by the World Organisation for Animal Health (OIE) and the Codex Alimentarius Commission (CAC). OIE standards focus on animal health and zoonoses and those of the CAC on food safety, but since zoonoses can affect food safety, it is vital that the two organisations cooperate closely to avoid duplication of effort, gaps and conflicting standards. The OIE has established an Animal Production Food Safety Working Group to promote cooperation with the CAC and to act as a steering committee for the OIE's work programme on the development of standards aimed at protecting consumers from foodborne hazards arising from animals at the production level of the food chain. This paper describes briefly how standards are developed by the OIE and the CAC and gives examples of how the tasks and standards of the two organisations complement each other in helping to assure food safety. The areas covered include meat hygiene, the identification and traceability of live animals, model certificates for international trade, antimicrobial resistance, veterinary drugs, animal feed, and salmonellosis. PMID:17094713

137

Defining the Core Archive Data Standards of the International Planetary Data Alliance (IPDA)  

A goal of the International Planetary Data Alliance (lPDA) is to develop a set of archive data standards that enable the sharing of scientific data across international agencies and missions. To help achieve this goal, the IPDA steering committee initiated a six month proj ect to write requirements for and draft an information model based on the Planetary Data System (PDS) archive data standards. The project had a special emphasis on data formats. A set of use case scenarios were first developed from which a set of requirements were derived for the IPDA archive data standards. The special emphasis on data formats was addressed by identifying data formats that have been used by PDS nodes and other agencies in the creation of successful data sets for the Planetary Data System (PDS). The dependency of the IPDA information model on the PDS archive standards required the compilation of a formal specification of the archive standards currently in use by the PDS. An ontology modelling tool was chosen to capture the information model from various sources including the Planetary Science Data Dictionary [I] and the PDS Standards Reference [2]. Exports of the modelling information from the tool database were used to produce the information model document using an object-oriented notation for presenting the model. The tool exports can also be used for software development and are directly accessible by semantic web applications.

138

Product carbon footprint developments and gaps  

Purpose - Over the last decade, multiple initiatives have been undertaken to learn how to capture the carbon footprint of a supply chain at a product level. The purpose of this paper is to focus on the process of standardization to secure consistency of product carbon footprinting (PCF) and to outline how the current developments in PCF support the need for a standardized method to measure and report environmental performance in supply chains. Design/methodology/approach - This paper is based on a literature review and a review of international standards for PCF which brings knowledge of PCF to the existing literature of green supply chain management. Findings - The multiple initiatives for standardization each improve the understanding of standardized methods of conducting PCF. At the sam...

139

Sharing data between facilities using the NeXus time-of-flight powder diffractometer file format  

NeXus is an international standard data format intended to reduce the need for redundant software development efforts in the neutron and x-ray scattering communities. As the NeXus standard matures it is starting to be used at laboratories for storing raw data. The Manuel Lujan Jr. Neutron Scattering Center (MLNSC) at Los Alamos National Laboratory and the Intense Pulsed Neutron Source (IPNS) at Argonne National Laboratory have been working with NeXus in an effort to share data and software. MLNSC is now writing files compliant with NeXus and the Integrated Spectral Analysis Workbench (ISAW) software from IPNS is being used with this data. Problems can arise if the standard is interpreted in different ways and information that belongs in the file is not accounted for in the standard. This paper will discuss an inter-laboratory collaboration in relation to a maturing data standard.

140

Development of a personalized dosimetric tool for radiation protection in case of internal contamination and targeted radiotherapy in nuclear medicine; Developpement d'un outil dosimetrique personnalise pour la radioprotection en contamination interne et la radiotherapie vectorisee en medecine nucleaire  

Current internal dosimetric estimations are based on the M.I.R.D. formalism and used standard mathematical models. These standard models are often far from a given patient morphology and do not allow to perform patient-specific dosimetry. The aim of this study was to develop a personalized dosimetric tool, which takes into account real patient morphology, composition and densities. This tool, called O.E.D.I.P.E., a French acronym of Tool for the Evaluation of Personalized Internal Dose, is a user-friendly graphical interface. O.E.D.I.P.E. allows to create voxel-based patient-specific geometries and associates them with the M.C.N.P.X. Monte Carlo code. Radionuclide distribution and absorbed dose calculation can be performed at the organ and voxel scale. O.E.D.I.P.E. can be used in nuclear medicine for targeted radiotherapy and in radiation protection in case of internal contamination. (author)

 
 
 
 
141

Energy conservation on exposed domestic sites  

The internal heat gains from solar radiation in two unoccupied isolated houses resulting from external climatic factors were recorded over a two year period at Oakpark Research Centre, Carlow, Ireland. Different recording regimes were undertaken with altered site characteristics mostly windbreaks. Using the monitored data, regression models for each regime were generated which related internal ambient temperature to the external climatic parameters. A model was developed to withstand the difficulties imposed by short monitoring periods and these regression models were used to predict internal temperatures for a standard reference year. Thus resulting energy saving for different site characteristics were estimated. The savings due to the erection of a windbreak were in the region of 5% to 10% and the savings accruing from the use of a standard low energy house was about 70% over a basic house. The possible implications of these savings for Ireland and Europe are outlined.

142

The Interplanetary Internet: a communications infrastructure for Mars exploration.  

A strategy is being developed whereby the current set of internationally standardized space data communications protocols can be incrementally evolved so that a first version of an operational "Interplanetary Internet" is feasible by the end of the decade. This paper describes its architectural concepts, discusses the current set of standard space data communications capabilities that exist to support Mars exploration and reviews proposed new developments. We also speculate that these current capabilities can grow to support future scenarios where human intelligence is widely distributed across the Solar System and day-to-day communications dialog between planets is routine. PMID:14649259

143

Ecological crisis in eastern Europe. (Latest citations from Pollution Abstracts database). Published Search  

The bibliography contains citations concerning the severe problem of chemical pollution in Eastern Europe. The citations examine the contamination of air, soil, and water by pollutants from agriculture, energy production, chemical plants, and oil refineries, including adverse health effects of chemical pollution. Topics also include international cooperation between Eastern Europe and western nations to exchange information, standardize pollution monitoring techniques, and establish environmental legislation compatible with western standards. The development of remediation technologies, and economic incentives which would promote environmental protection while fostering future economic developments are also discussed. (Contains 250 citations and includes a subject term index and title list.)

144

Life cycle assessment of switchgrass-derived ethanol as transport fuel  

Background, aim, and scope The increasing gasoline price, the depletion of fossil resources, and the negative environmental consequences of driving with petroleum fuels have driven the development of alternative transport fuels. Bioethanol, which is converted from cellulosic feedstocks, has attracted increasing attention as one such alternative. This study assesses the environmental impact of using ethanol from switchgrass as transport fuel and compares the results with the ones of gasoline to analyze the potential of developing switchgrass ethanol as an environmentally sustainable transport fuel. Methods The standard framework of life cycle assessment from International Standards Organization was followed. To compare the environmental impact of driving with E10 and E85 with gasoline, ?pow...

145

Faith Community Nurses: Implementing Healthy People Standards to Promote the Health of Elderly Clients  

The face of aging in our society has changed dramatically over the past generation. Many seniors struggle to access needed services, which include health promotion and disease prevention activities. A "Parish Nurse Questionnaire" was developed by the authors using the Healthy People 2010 Critical Health Indicators, the International Parish Nurse Resource Center functions of the parish (faith community) nurse, and the ANA Scope and Standards for Faith Community Nurses to ascertain if, and how frequently, faith community nurses practice interventions that address strategies mandated by theses organizations. Data collected on 102 participants supported that the faith community nurse model of community-based practice guides the development of strategies addressing those established standards. ...

146

PulseNet USA Standardized Pulsed-Field Gel Electrophoresis Protocol for Subtyping of Vibrio parahaemolyticus  

PulseNet is a national molecular subtyping network for foodborne disease surveillance composed of public health and food regulatory agencies. Participants employ molecular subtyping of foodborne pathogens using a standardized method of pulsed-field gel electrophoresis (PFGE) for conducting laboratory-based surveillance of foodborne pathogens. The PulseNet standardized PFGE protocols are developed through a comprehensive testing process. The reproducibility of the protocol undergoes an internal evaluation at the Centers for Disease Control and Prevention and an external evaluation in multiple PulseNet laboratories. Here we describe the development and evaluation of a rapid PFGE protocol for subtyping Vibrio parahaemolyticus for use in PulseNet activities. The protocol was derived from the e...

147

Development of a stable isotope dilution analysis for the quantification of the Bacillus cereus toxin cereulide in foods.  

An increasing number of severe food borne intoxications are caused by a highly stable depsipeptide, named cereulide, which is produced by emetic Bacillus cereus strains. As cereulide poses a health risk to humans, the development of an appropriate method for the analysis of this toxin is mandatory. Therefore, the reference material of cereulide as well as its (13)C(6)-isotopologue was prepared by means of a biosynthetic approach using a B. cereus culture, followed by a rapid but efficient downstream purification. After structure confirmation by means of liquid chromatography (LC)-time-of-flight mass spectrometry, LC-tandem mass spectrometry, and one-/two-dimensional NMR spectroscopy, a stable isotope dilution analysis (SIDA) was developed for the quantification of cereulide in foods using the (13)C(6)-cereulide as the internal standard. Validation experiments were performed, and the data were compared to the quantitative analysis using the structurally related valinomycin instead of the (13)C(6)-cereulide as an internal standard. Trueness, repeatability, and reproducibility expressed as relative standard deviation showed values valinomycin or valinomycin was found to be significantly influenced by the food matrix, thus leading to rather low recovery rates of 91% from boiled rice and 80% from boiled rice supplemented with 10% sunflower oil. In comparison, the use of (13)C(6)-cereulide as an internal standard gave good recovery rates of 104 and 111% from both matrices, thus demonstrating the robustness and accuracy of the developed SIDA. PMID:19994891

148

Preparation and Evaluation of a Chrysotile Asbestos-containing Standard Material for Validating X-Ray Diffractometric Quantitation  

A standard material containing chrysotile asbestos for the validation of x-ray diffractometric quantitation was developed using an asbestos-containing building material i.e., perlite board. The board as the base material was crushed, pulverized, and homogenized. The homogeneity of the powder of perlite board was estimated by analysis of variance. The diffraction intensity values of the crystalline phases and the concentrations of elements determined by x-ray diffractometry and x-ray fluorescence analysis were used for analysis of variance. There is no significant difference between the within-bottle variance and the between-bottle variance, indicating that the powdered perlite board was sufficiently homogenous. The concentration of chrysotile in the material was determined using two methods: an internal standard/x-ray diffractometry method and the x-ray diffractometry/Rietveld refinement. The concentration of chrysotile in the material was determined by an internal standard/x-ray diffractometry method and the material had a chrysotile concentration of 24.1 ± 0.2 mass%.   

149

Designing serological surveillance programmes to document freedom from disease with special reference to exotic viral diseases of pigs in Denmark  

Surveillance programmes based on laboratory screening tests are increasingly used to document freedom from disease in order to facilitate trade, The following aspects must be considered when designing such programmes: diseases to be selected; epidemiology of the diseases; unit of analysis (animal or herd); target age group (or target farm type); test characteristics and sample size. Issues related to these aspects are discussed and illustrated using the example of serological surveillance for exotic viral diseases in the pig population of Denmark, Sampling designs based on individual animal samples are compared with herd-based sampling (two-stage sampling). While the latter is likely to require a larger sample size, the increased level of information and the reliability of the results obtained are considered to be worth the expense. Issues related to the development of international standards for declaring freedom from disease are discussed. The authors conclude that international standards are desirable, providing that these standards represent scientifically valid principles.

150

Use of an internal standard /sup 233/U, /sup 236/U to improve the accuracy of isotopic uranium analysis by thermal ionization mass spectrometry. Application to isotope dilution analysis  

A method using a calibrated mixture of isotopes /sup 233/U and /sup 236/U has been developed in order to correct the isotopic fractionation which limits the accuracy of isotopic analysis by thermal ionization mass spectrometry. The 236/233 internal standard ratio is calibrated against the 235/238 ratios of uranium isotopic standards. To perform the analysis of the unknown sample, the latter is mixed with the internal standard, the differences between the true value and the observed values of the 236/233 ratio allows the determination of a correction factor, which is applied to the measured 235/238 ratio values. Since 1978, /sup 235/U abundance measurements on a series of samples have been performed, using this technique; data are obtained with an accuracy better than 0.05%. It is intended to apply this method for precise determination of 238/233 ratio in the case of uranium concentration measurements by isotope dilution.

151

Assessment of the capabilities of capillary zone electrophoresis for the determination of hippuric and orotic acid in whey.  

A rapid method was developed for the simultaneous determination of hippuric and orotic acid in rennet whey by capillary zone electrophoresis using an uncoated capillary utilizing a 0.04 M amino-2-methyl-1,3-propanediol (AMPD)-N,N-bis(2-hydroxyethyl) glycine (BICINE) buffer (pH 8.8) with UV detection at 254 and 280 nm. Whey proteins were removed by ultrafiltration. The method was evaluated for external, internal and standard addition procedures for both peak areas and peak heights. The use of an internal standard (sorbic acid) eliminated injection errors and gave, when applied to peak areas, the same levels for hippuric and orotic acid in those obtained with high-performance liquid chromatography. Relative standard deviations were 1-2%. Peak heights gave erratic results owing to sample matrix effects on peak widths. PMID:1430035

152

A Simple and Highly Sensitive HPLC Method with Fluorescent Detection for Determination of Pipecolic Acid in Mouse Brain Areas  

A simple and highly sensitive high-performance liquid chromatography method for the determination of pipecolic acid in mouse brain areas was developed. After homogenization of brain and pretreatment with o-phthalaldehyde, the pipecolic acid and (2S,3S)-3-methylpyrrolidine-2-carboxylic acid (internal standard) were derivatized with 4-(5,6-dimethoxy-2-phthalimidinyl)-2-methoxyphenylsulfonyl chloride at 70 °C for 15 min in basic medium (pH 9.0). The fluorescent derivatives of pipecolic acid and internal standard were separated on a reversed-phase column by stepwise elution using acetic acid (30 mM)–acetonitrile at 50 °C and detected by fluorescence measurement at 316 nm (excitation) and 403 nm (emission). The detection limit (signal-to-noise ratio=3) of pipecolic acid was 13 fmol per injection. The recovery was about 106.7%. The precision (relative standard deviation) was 3.2%.   

153

Developing evidence-based standards for diagnosis and management of lower urinary tract or pelvic floor dysfunction  

Abstract The International Continence Society (ICS) has a key role in standardizing terminology related to lower urinary tract and pelvic organ dysfunction. The ICS Standardization Steering Committee (SSC) presents the new structure and process by which future ICS Standards will be developed. The new processes aim to meet present-day evidence-based practice requirements, and to foster unbiased, inclusive, and transparent development. For each new ICS Standard, the SSC will oversee a dedicated ad hoc Working Group (WG). Applications to chair or contribute to a WG will be invited from the ICS membership. The SSC will select the Chairperson, and work with him or her to select the WG composition, balanced to represent key disciplines, stakeholders, and regions. Consultants can be invited to co...

154

New internal standard method for activation analysis and its application. Determination of Co, Ni, Rb, Sr in pepperbush by means of photon activation  

A new internal standard method for activation analysis has been developed. In this method a suitable element present originally in the sample is used as an internal standard and the comparative standard is prepared by applying the standard addition method to the duplicated sample. The present method has the great advantages that the comparative standard spiked with the element of interest has the same matrix as the sample, and then the amount of the element to be determined in the sample can be evaluated easily by using a very simple equation even though the sample and comparative standard are irradiated separately by particles with different flux. Neither correction of the inhomogeneities of flux between the sample and comparative standard, nor that of the self-shielding effects are necessary for the present method. The usefulness of the method was examined through the determination of Co, Ni, Rb and Sr in pepperbush by means of photon activation, and the precision and accuracy of the method were proved to be valid. 29 refs.

155

Method to Solve the Problem of the Radioactivity Detection in Environmental Samples. Characteristic Limits; Metodos para la Resolucion del Problema de la Detecfcion de Radiactividad en Muestras Ambientales. Limites Caracteristicos  

The problem of the detection or when the radioactivity can be considered as higher than the background using different measurement techniques has been the objective of several statistical studies and controversies. The detection limit and the critical limit were studied by Currie in year 1968 and used by radiochemistry laboratories considering different ways of calculation that introduced confusion and not correct implementations. In the last few years, and due to the increasing number of standardization processes on the field of radioactivity and accreditation, several international institutions have chosen to unify the criteria for using common determination of detection limits. The most used methods are those developed by MARLAP and International Standard Organization ISO (Standard-11929). In this report are summarised both standards doing a comparative study and giving some examples of how to apply these limits. In same cases, little differences in the uncertainty calculation have been observed but the final results have been concordant. A deeply study of these standards can be done consulting the web page of the American Labs that developed MARLAP or buying the original ISO standard ISO-11929 recently approved (2009). (Author) 17 refs.

156

Antimicrobial resistance and the guidelines of the International Cooperation on Harmonisation of Technical Requirements for Registration of Veterinary Medicinal Products (VICH).  

The International Cooperation on Harmonisation of Technical Requirements for Registration of Veterinary Medicinal Products (VICH) is an international tripartite cooperation programme that brings together regulatory authorities and industry representatives from the European Union, Japan and the United States, with Australia, New Zealand and Canada as observers. VICH aims to improve international coordination and cooperation to achieve greater harmonisation of the requirements for veterinary product registration in the regions concerned. VICH develops harmonised data requirements, i.e., standards for the scientific studies on quality, safety and efficacy that are required to obtain a marketing authorisation for a veterinary medicinal product. It does this by publishing guidelines that provide uniform and consistent guidance for sponsors to follow in developing data for application dossiers as well as for post-marketing safety monitoring of veterinary medicinal products. Of the 49 VICH guidelines that have been developed so far, two guidelines in particular address issues related to antimicrobial resistance. PMID:22849284

157

The globalization of intelligence since 9/11 : frameworks and operational parameters  

"Abstract: In the early 21st century we are witnessing the increasing globalization of intelligence. The phenomenon of international intelligence liaison is central to this process, an area where intelligence and international relations connect. This article highlights the key themes that are currently developing within international intelligence liaison relationships. It asserts that we can identify a trend towards ‘homogenization’ of intelligence and other law enforcement and security initiatives. It even suggests we may speak of something close to ‘international standardization’ among a widening group of partners. These processes are underway to establish viable frameworks and operational parameters for the intelligence liaison arrangements, together with addressing counterintelligence and other security considerations. These convergent ‘regimes’ contribute to the important processes of trust and confidence building, as well as their subsequent maintenance over time. In short, a ‘best practice’ approach is becoming ‘normalized’ operationally, facilitating the optimization of intelligence liaison arrangements." - From journal.

158

Revisors kompetence - efteruddannelse  

Nærværende artikel behandler efteruddannelseskravene for revisorer. Først præsenteres kravene for godkendte revisorer i afsnit 1 om de kompetencekrav, der stilles for at opnå godkendelse, og i afsnit 2 om efteruddannelseskravene, som de med virkning fra 1.1. 2009 er udmøntet i revisorloven (RL), efteruddannelsesbekendtgørelsen og en uddybende vejledning. Et særligt fokusområde i afsnit 2 er kravene til indberetning og især til dokumentation. I afsnit 3 behandles der særlige forhold ved deponering af godkendelse, mens afsnit 4 fremfører synspunkter på reglernes betydning i intern revision, herunder afsmitning på revisionschefer, der ikke er godkendte revisorer, samt på medarbejdere. IIA har egne retningslinjer for efteruddannelse, nr. 1230 under Standards for the Professional Practice of Internal Auditing, der forpligter interne revisorer til "Continuing Professional Development" uden specificerede krav. Hvis intern revisor har en af specialistuddannelserne - CIA m.v. - er der derimod sådanne krav, der dog ikke behandles her. Udgivelsesdato: April 2010

159

The emerging international regulatory framework for biotechnology.  

Debate about the potential risks of genetically modified organisms (GMOs) to the environment or human health spurred attention to biosafety. Biosafety is associated with the safe use of GMOs and, more generally, with the introduction of non-indigenous species into natural or managed ecosystems. Biosafety regulation--the policies and procedures adopted to ensure the environmentally safe application of modern biotechnology--has been extensively discussed at various national and international forums. Much of the discussion has focused on developing guidelines, appropriate legal frameworks and, at the international level, a legally binding international biosafety protocol--the Cartagena Protocol on Biosafety. The Protocol is one among various international instruments and treaties that regulate specific aspects relevant to agricultural biotechnology. The present article presents the main international instruments relevant to biosafety regulation, and their key provisions. While international agreements and standards provide important guidance, they leave significant room for interpretation, and flexibility for countries implementing them. Implementation of biosafety at the national level has proven to be a major challenge, particularly in developing countries, and consequently the actual functioning of the international regulatory framework for biotechnology is still in a state of flux. PMID:22430851

160

Lessons Learned in Building VO Resources: Binding Together Several VO Standards into an Operational Service  

The International Virtual Observatory Alliance (IVOA) developed numerous interoperability standards during the last several years. Most of them are quite simple to implement from the technical point of view and even contain “SIMPLE” in the title. Does it mean that it is also simple to build a working VO resource using those standards? Yes and no. “Yes” because the standards are indeed simple, and “no” because usually one needs to implement a lot more than it was thought in the beginning of the project so the time management of the team becomes difficult. In our presentation we will start with a basic case of a simple spectral data collection. Then we will describe several examples of “small” technologically advanced VO resources built in CDS and VO-Paris and will show that many standards are hidden from managers' eyes at the initial stage of the project development. The projects will be: (1) the GalMer database providing access to the results of numerical simulations of galaxy interactions; (2) the full spectrum fitting service that allows one to extract internal kinematics and stellar populations from spectra of galaxies available in the VO. We conclude that: (a) with the existing set of IVOA standards one can already build very advanced VO-enabled archives and tools useful for scientists; (b) managers have to be very careful when estimating the project development timelines for VO-enabled resources.

 
 
 
 
161

ISO standardization of scaling factor method for low and intermediate level radioactive wastes generated at nuclear power plants  

Low- and intermediate-level radioactive wastes (L-ILW ) generated at nuclear power plants are disposed of in various countries. In the disposal of such wastes, it is required that the radioactivity concentrations of waste packages should be declared with respect to difficult-to-measure nuclides (DTM nuclides), such as C-14, Ni-63 and a-emitting nuclides, which are often limited to maximum values in disposal licenses, safety cases and/or regulations for maximum radioactive concentrations. To fulfill this requirement, the Scaling Factor method (SF method) has been applied in various countries as a principal method for determining the concentrations of DTM nuclides. In the SF method, the concentrations of DTM nuclides are determined by multiplying the concentrations of certain key nuclides by SF values (the determined ratios of radioactive concentration between DTM nuclides and those key nuclides). The SF values used as conversion factors are determined from the correlation between DTM nuclides and key nuclides such as Co-60. The concentrations of key nuclides are determined by {gamma} ray measurements which can be made comparatively easily from outside the waste package. The SF values are calculated based on the data obtained from the radiochemical analysis of waste samples. The use of SFs, which are empirically based on analytical data, has become established as a widely recognized 'de facto standard'. A number of countries have independently collected nuclide data by analysis over many years and each has developed its own SF method, but all the SF methods that have been adopted are similar. The project team for standardization had been organized for establishing this SF method as a 'de jure standard' in the international standardization system of the International Organization for Standardization (ISO). The project team for standardization has advanced the standardization through technical studies, based upon each country's study results and analysis data. The conclusions reached by the project team was published as ISO International Standard 21238:2007 'The Scaling Factor method to determine the radioactivity of low- and intermediate-level radioactive waste packages generated at nuclear power plants'. This paper gives an introduction to the international standardization process for the SF method and the contents of the recently published International Standard. (authors)

162

Technical Review of Law Enforcement Standards and Guides Relative to Incident Management  

In an effort to locate potential law enforcement-related standards that support incident management, a team from the Pacific Northwest National Laboratory (PNNL) contacted representatives from the National Institute of Standards-Office of Law Enforcement Standards (NIST-OLES), National Institute of Justice (NIJ), Federal Bureau of Investigation (FBI), Secret Service, ASTM International committees that have a law enforcement focus, and a variety of individuals from local and regional law enforcement organizations. Discussions were held with various state and local law enforcement organizations. The NIJ has published several specific equipment-related law enforcement standards that were included in the review, but it appears that law enforcement program and process-type standards are developed principally by organizations that operate at the state and local level. Input is provided from state regulations and codes and from external non-government organizations (NGOs) that provide national standards. The standards that are adopted from external organizations or developed independently by state authorities are available for use by local law enforcement agencies on a voluntary basis. The extent to which they are used depends on the respective jurisdictions involved. In some instances, use of state and local disseminated standards is mandatory, but in most cases, use is voluntary. Usually, the extent to which these standards are used appears to depend on whether or not jurisdictions receive certification from a “governing” entity due to their use and compliance with the standards. In some cases, these certification-based standards are used in principal but without certification or other compliance monitoring. In general, these standards appear to be routinely used for qualification, selection for employment, and training. In these standards, the term “Peace Officer” is frequently used to refer to law enforcement personnel. This technical review of national law enforcement standards and guides identified the following four guides as having content that supports incident management: • TE-02-02 Guide to Radio Communications Interoperability Strategies and Products • OSHA 335-10N Preparing and Protecting Security Personnel in Emergencies • NIJ 181584 Fire and Arson Scene Evidence: A Guide for Public Safety Personnel • NIJ 181869 A Guide for Explosion and Bombing Scene Investigation In conversations with various state and local law enforcement officials, it was determined that the following National Fire Protection Association (NPFA) standards are generally recognized and tend to be universally used by law enforcement organizations across the country: • NFPA 1600 Standard on Disaster/Emergency Management and Business Continuity Programs • NFPA 1561 Standard on Fire Department Incident Management Systems • NFPA 472 Standard for Competence of Responders to Hazardous Materials/Weapons of Mass Destruction Incidents (2008 Edition) • NFPA 473 Standard for Competencies for EMS Personnel Responding to Hazardous Materials/Weapons of Mass Destruction Incidents (2008 Edition)

163

Developing evidence-based standards for diagnosis and management of lower urinary tract or pelvic floor dysfunction.  

The International Continence Society (ICS) has a key role in standardizing terminology related to lower urinary tract and pelvic organ dysfunction. The ICS Standardization Steering Committee (SSC) presents the new structure and process by which future ICS Standards will be developed. The new processes aim to meet present-day evidence-based practice requirements, and to foster unbiased, inclusive, and transparent development. For each new ICS Standard, the SSC will oversee a dedicated ad hoc Working Group (WG). Applications to chair or contribute to a WG will be invited from the ICS membership. The SSC will select the Chairperson, and work with him or her to select the WG composition, balanced to represent key disciplines, stakeholders, and regions. Consultants can be invited to contribute to the WG where specific need arises. Every WG will review current knowledge, adhering to evidence-based medicine requirements. Progress reports will be reviewed by the SSC, and amendments recommended, culminating in a first draft. The draft will be offered to the ICS membership and additional relevant experts for comment. Further revision, if needed, will result in a document, which the SSC will submit to the ICS Trustees, as arbiters of whether the document should be adopted as an ICS Standard. The SCC will then coordinate with the WG to ensure that the new ICS Standard is published and disseminated. Implementation strategies, such as education, audit, accreditation, and research initiatives will be linked to the Standards where appropriate. Revisions of ICS Standards will be undertaken to maintain contemporaneous relevance. PMID:22396134

164

International standards for the exploration and production industry -- Their development and use  

A single global market for procurement is of crucial importance to the E and P industry. The resulting benefits, including cost reductions and shorter delivery times, could even be the key to the economic development of marginal fields. International Standards that cater for the needs of users, manufacturers and the public at large can provide a common basis for companies to procure and provide goods and services that will deliver the required performance throughout the field life. The savings to industry could be billions of dollars per year. The E and P Forum, on behalf of the industry, has developed proposals to increase the efficiency of this managerial procedure and to speed up the ``internationalization`` of selected standards. Details are given at the end of the paper. It is argued that the E and P industry should rally to the cause of international standardization. Companies should lend their full support by committing their valuable expert resources. It is in the interests of the industry to do this for, without suitably skilled expert representation in ISO and the elimination of duplication as well as waste of resources through performing similar work at company or national level, the large potential benefits of international standardization will elude the E and P industry.

165

OSI in the NASA science internet: An analysis  

The Open Systems Interconnection (OSI) protocol suite is a result of a world-wide effort to develop international standards for networking. OSI is formalized through the International Organization for Standardization (ISO) and the International Electrotechnical Commission (IEC). The goal of OSI is to provide interoperability between network products without relying on one particular vendor, and to do so on a multinational basis. The National Institute for Standards and Technology (NIST) has developed a Government OSI Profile (GOSIP) that specified a subset of the OSI protocols as a Federal Information Processing Standard (FIPS 146). GOSIP compatibility has been adopted as the direction for all U.S. government networks. OSI is extremely diverse, and therefore adherence to a profile will facilitate interoperability within OSI networks. All major computer vendors have indicated current or future support of GOSIP-compliant OSI protocols in their products. The NASA Science Internet (NSI) is an operational network, serving user requirements under NASA's Office of Space Science and Applications. NSI consists of the Space Physics Analysis Network (SPAN) that uses the DECnet protocols and the NASA Science Network (NSN) that uses TCP/IP protocols. The NSI Project Office is currently working on an OSI integration analysis and strategy. A long-term goal is to integrate SPAN and NSN into one unified network service, using a full OSI protocol suite, which will support the OSSA user community.

166

Fiscal 1997 survey report. Subtask 2 (hydrogen utilization worldwide clean energy system technology) (WE-NET) (survey/study for the promotion of international cooperation; survey/study on the standardization for hydrogen energy technology); 1997 nendo seika hokokusho. Suiso riyo kokusai clean energy system gijutsu (WE-NET) subtask 2 kokusai kyoryoku suishin no tame no chosa kento (suiso energy gijutsu hyojunka ni kansuru chosa kento)  

In relation to the basic study of the standardization for hydrogen energy technology and ISO/TC197, the results of the fiscal 1997 survey were summarized. From fiscal 1994 through 1996, in the wide-range field related to hydrogen energy technology, the survey of the present situation of the related standards/laws was made and the needs/subjects of standardization to be studied in the future were extracted. At the present stage, however, it is still early to enter into the stage of discussing the standardization. Therefore, in this fiscal year, only in the field of the storage/transportation/handling of liquid hydrogen, standards/laws abroad and in Japan were comparatively investigated for the basic study toward the standardization. Further, concerning ISO/TC197, studies were proceeded with of the liquid hydrogen land vehicle fueling system interface/fuel tanks/transportation containers/hydrogen fuel product specifications/airport hydrogen fueling facilities. Some are at the stage of drafting the international standard. Three drafts for the new standard were added such as gaseous hydrogen/hydrogen blend vehicular fuel systems, gaseous hydrogen fuel tanks, and basic requirements for safety of hydrogen systems. The standardization is indispensable to introducing the developed technology to the commercialization. 9 refs., 5 figs., 13 tabs.

167

Computational Analysis of Coriant and PNNL Radioxenon Data Viewers  

The analysis by Coriant of the beta-gamma coincidence data coming from the ARSA systems show a systematic basis towards lower concentrations for all isotopes and a systematic increase in the minimum detectable concentrations. These variations can be directly traced to the method of analysis that is used by the Coriant software compared to the methods that have been developed by the International Noble Gas Experiment collaboration. This report details the differences and suggests solutions where appropriate. The report writers recommend that the algorithm changes be made to the Coriant software to bring up to the international standards.

168

A rate-dependent incremental variational formulation of ferroelectricity  

This paper presents a variational-based modeling and computational implementation of the non-linear, rate-dependent response of piezoceramics under electro-mechanical loading. The point of departure is a general internal variable formulation that describes the hysteretic electro-mechanical response of the material as a standard dissipative solid. Consistent with this type of dissipative continua, we develop a variational formulation of the coupled electro-mechanical boundary-value-problem based on incremental potentials for the stresses and the electric displacement. We specify the variational formulation to a model that describes time-dependent, electric polarizations accompanied by remanent strains. It is governed by a dual dissipation function formulated in terms of the internal driving...

169

Market or geopolitics? The Europeanization of EU's energy corridors  

Purpose - The purpose of this article is to explore an energy strategy for the European Union (EU) that could integrate the tensions between geopolitics and the market in a coherent and consistent external EU energy policy. Design/methodology/approach - The approach consists of combining the theoretical framework of international political economy and Europeanization to European energy corridors. Findings - The article finds that most qualitative energy security scenarios can be conceived as applications of international political economy paradigms. Its main result is to conceptually develop a geo-economic strategy consisting on the Europeanization of EU's external energy corridors along its own energy regulations and standards. Research limitations/implications - The article explores a di...

170

Synopsis of the results of ISP-39 on FARO test L-14  

This paper provides a synopsis of the salient results from the ISP(International Standard Problem)-39 exercise promoted by OECD-CSNI in the frame of the NEA activities aimed at fostering international cooperation in reactor safety research and development. ISP-39 has been conceived to benchmark the predictive capabilities of computer codes used in the evaluation of FCI and quenching phenomenologies of relevance in water cooled reactors severe accidents safety analysis. The ISP-39 reference case is FARO test L-14, a non-energetic FCI test performed in the FARO experimental installation under realistic melt composition and prototypical test conditions. (author)

171

Kinship, culture and ethics in organisations: Exploring implications for internal communication  

Purpose - This article aims to report the results of an international survey (USA and New Zealand) that tested relationship effects on ethical behaviour. The findings point to the impact of perceived social bonds on ethical decision-making. They also reinforce the cultural specificity of ethics. Both these findings confirm the importance of participatory, ground-up, discussion-based approaches to developing organisational ethical standards. The article discusses some implications of these findings for internal communicators involved with ethics programmes in organisations. Design/methodology/approach - The research used an established scenario-style survey to test respondents' ethical decision-making behaviours under different circumstances. Findings - This article discusses two results th...

172

Development and experimental study of the neutron beam at the synchrocyclotron of the Petersburg Nuclear Physics Institute for radiation tests of electronic components  

A neutron beam with an energy spectrum resembling that of atmospheric neutron radiation has been developed at the 1000-MeV synchrocyclotron of the Petersburg Nuclear Physics Institute. The beam is intended for testing the radiation resistance of electronics and meets the requirements of the JEDEC international standard. The only test facility in which the neutron spectrum is close to the standard in the energy range of 0.1?750 MeV has been developed at the Los Alamos National Laboratory on the basis the LAMPF linear proton accelerator and used by aviation and space companies of the United States, Europe, and Asia to test their electronic equipment. In contrast to the test facilities in Los Alamos and Uppsala (Sweden), the method of neutron production on an internal accelerator target is us...

173

Validation of the French version of the Sociocultural Attitudes Towards Appearance Scale-3 (SATAQ-3)  

Body image literature suggests that the sociocultural environment contributes to the development and maintenance of body dissatisfaction and eating disorders by conveying thin standards of thinness. Three main sources of sociocultural influences were highlighted: family, peers and media. These three sources of pressure can lead to the internalization of messages about the importance of thinness and beauty. Among the various sources of sociocultural influences, media appear to be the most powerful communicator of these standards. Thompson et al. [Intern J Eat Disord 35 (2004) 293-304] developed a multidimensional questionnaire to assess the sociocultural influence of media on appearance: The Sociocultural Attitudes Towards Appearance Scale-3 (SATAQ-3). The SATAQ-3 is a 30-item scale compose...

174

Direct quantification of morphine glucuronides and free morphine in urine by liquid chromatography???tandem mass spectrometry  

A simple and robust liquid chromatographic-tandem mass spectrometric method was developed and validated for the direct quantification of the structural isomers morphine-3-glucuronide (M3G), morphine-6-glucuronide (M6G), and morphine in urine. Method development showed that dilution of the urine samples was mandatory to obtain reproducible chromatography and that the use of deuterated internal standards was needed to compensate for ion suppression. Sample preparation consisted of a 20-fold dilution of urine into the internal standard solution. Chromatography was performed on a C8-column using gradient conditions. The mobile phase consisted of water/methanol, both containing 0.1 % acetic acid and 1 mM ammonium acetate. Calibration curves were constructed between 0.05 and 2 ?g/ml. Validat...

175

How to Lose Friends and Turn People against You: Organisational Development Tools--What They Are and How We Use Them in Higher Education  

This paper is based on a keynote speech delivered to the AUA Annual Conference, Belfast, April 2006. It discusses the concept of organisational development as it applies to universities, where internally developed approaches applying some of the core principles of standard frameworks are the norm. The author discusses several organisational development tools in use in higher education: (1) Investors in People; (2) The EFQM Excellence Model; (3) The Balanced Scorecard; (4) Spiral Dynamics; and (5) Appreciative Enquiry. He concludes that the usefulness of most ID approaches lies in the differing pOrganizational Development;Higher Education;Attitude Change;Adjustment (to Environment);erspectives they offer on how an organisation operates. (Contains 1 table.)

176

Geothermal research at Oklahoma State University: An integrated approach  

Oklahoma State University and the International Ground Source Heat Pump Association (IGSHPA) are active in providing technical support to government and industry through technology transfer, technology development, technical assistance, and business development support. Technology transfer includes geothermal heat pump (GHP) system training for installers and architects and engineers, national teleconferences, brochures, and other publications. Technology development encompasses design software development, GLHEPRO, in-situ thermal conductivity testing methods and verification of data reduction techniques, and specifications and standards for GHP systems. Examples of technical assistance projects are a Navy officers quarters and a NASA Visitors Center which required design assistance and supporting information in reducing the life cycle cost to make them viable projects.

177

28. annual offshore technology conference: Proceedings. Volume 2: Platform and marine system design  

The 83 papers in this volume cover the following topics: advances in subsea technology offshore Brazil; development of international standards for design of offshore platforms to resist earthquakes; floating production--design and conversion; floating production technology; floating production units; Heidrun field development; loading of offshore structures; mudslide platform development at SP47; project management; risk assessment; safety and environmental quality; structural design and platform reassessment; The Atlantic Frontier--an overview; and The Atlantic Frontier--Foinaven field development. All papers have been processed separately for inclusion on the data base.

178

International Workshop on Gamma Spectrometry Analysis Codes for U and Pu Isotopics: Workshop Results and Next Steps  

In November 2008, the Institute of Nuclear Materials Management (INMM) and the European Safeguards Research and Development Association (ESARDA) co-hosted the International Workshop on Gamma Spectrometry Analysis Codes for U and Pu Isotopics at the Oak Ridge National Laboratory (ORNL). This workshop was conducted in response to needs expressed by the international safeguards community to understand better the capabilities and limitations of the codes; to ensure these codes are sustained; and to ensure updates or revisions are performed in a controlled manner. The workshop was attended by approximately 100 participants. The participants included code developers, code suppliers, safeguards specialists, domestic and international inspectors, process operators, regulators, and programme sponsors from various government agencies. The workshop provided a unique opportunity for code developers, commercial distributors and end users to interact in a hands-on laboratory environment to develop solutions for programmatic and technical issues associated with the various codes. The workshop also provided an international forum for discussing development of an internationally accepted standard test method. This paper discusses the organization of the workshop, its goals and objectives and feedback received from the participants. The paper also describes the significance of the working group's contribution to improving codes that are commonly used during inspections to verify that nuclear facilities are compliant with treaty obligations that ensure nuclear fuel cycle facilities are used for peaceful purposes.

179

Approach for Safety Assurance and Structural Integrity of ITER  

Following the Engineering Design Activity of ITER, joint implementation towards construction has been made among the international partners. To this end, in Japan, efforts have been made to develop a fundamental approach for ensuring safety and establishing associated codes and standards for structural and seismic integrity in licensing preparation. This paper gives an outline of a safety approach and presents an outline of technical codes for the integrity of unique ITER components.

180

Approach for safety assurance and structural integrity of ITER  

Following the Engineering Design Activity of ITER, joint implementation towards construction has been made among the international partners. To this end, in Japan, efforts have been made to develop a fundamental approach for ensuring safety and establishing associated codes and standards for structural and seismic integrity in licensing preparation. This paper gives an outline of a safety approach and presents an outline of technical codes for the integrity of unique ITER components. (author)

 
 
 
 
181

MCNP APPLICATIONS FOR THE 21ST CENTURY  

The Los Alamos National Laboratory (LANL) Monte Carlo N-Particle radiation transport code, MCNP, has become an international standard for a wide spectrum of neutron, photon, and electron radiation transport applications. The latest version of the code, MCNP 4C, was released to the Radiation Safety Information Computational Center (RSICC) in February 2000. This paper describes the code development philosophy, new features and capabilities, applicability to various problems, and future directions.

182

MCNP application for the 21 century  

The Los Alamos National Laboratory (LANL) Monte Carlo N-Particle radiation transport code, MCNP, has become an international standard for a wide spectrum of neutron, photon, and electron radiation transport applications. The latest version of the code, MCNP 4C, was released to the Radiation Safety Information Computational Center (RSICC) in February 2000. This paper describes the code development philosophy, new features and capabilities, applicability to various problems, and future directions.

183

Development of a stationary battery for high load with increased efficiency for load leveling  

A lead acid battery with lower internal resistance and higher specific capacity than standard was designed. An alloy for the positive grid was developed. The technology for auxiliary sytems for maintenance-free service, i.e., recombination, acid circulating, electrical acid density measuring, and acid level indication was tested. The optimum design is a module of five cells. A computer controlled pilot plant with a maximum output of 250 kW and a 2.2 hr duty time was put into service.

184

Analytical calculation of demagnetization in surface mounted ferrite magnet motors; Calcul analytique de la desaimantation dans les moteurs a aimants ferrite en surface  

An analytical method for the calculation of ferrite magnets demagnetization in brush-less motors equipped with surface-mounted magnets is developed. This method takes into account the internal field in the magnet. It's based on the resolution in polar coordinates of the governing field equations in the air-gap and the magnet regions. The obtained results are compared with standard demagnetization measurements like done in the automotive motors industry. (author)

185

Fuente sonora omni-direccional  

Abstract in spanish Se presenta el diseño, construcción y evaluación de una fuente acústica omni-direccional, desarrollada en nuestro laboratorio para aplicaciones en acústica. Su evaluación muestra que sus características cumplen con los requisitos exigidos en normas internacionales. Abstract in english The design, construction and evaluation of an omni-directional sound source is presented. It was developed in our laboratory for acoustic applications. The evaluation shows that its characteristics fulfill the requirements demanded by international standards.

186

Burners. The decrease of nitrogen oxides in combustion process: the 2 nd generation GR LONOxFLAM burner; Les bruleurs, la reduction des oxydes d`azote dans la combustion: bruleur GR LONOxFLAM de 2. generation  

The Pillard company has developed, in cooperation with GDF (the French national gas utility), the GR-LONOxFLAM burner concept for reducing NOx emission levels and solid combustion products. The concept consists, for gaseous fuels, in the combination of an internal recirculation and a gas staging process; for liquid fuels, a separated flame process and air staging are combined. These concepts allow for an important reduction in NOx and non-burned residues, even with standard-size burners

187

Reinforcement for pipe branch connections  

A program developed to determine whether a pipe having a branch connection has sufficient wall thickness to sustain the internal pressure, or whether additional reinforcement should be provided is described. Possibility of using standard fittings (tie, lateral, weldolet, sockolet) should be considered before applying a reinforcement ring, the size of which is determined by the program. In calculating the size of the ring, the program selects a thickness of the ring equal to the minimum pipe wall thickness.

188

Establishment of a tandem ionization chamber system in standard mammography beams  

A double-faced tandem ionization chamber system was developed at the Calibration Laboratory of IPEN. It has different collecting electrode materials: aluminium and graphite. The response repeatability and reproducibility and the energy dependence test of this tandem ionization chamber were evaluated. The chamber response stability is within the {+-}3% limit recommended in international standards. The energy dependence test of the ionization chamber system using the tandem curve obtained, presented agreement with literature results. (author)

189

Evaluation of the scientific basis for ozone/oxidants standards  

This summary of an APCA International Specialty Conference is an assessment of the current state on scientific knowledge regarding the health and welfare effects of ozone. Items addressed include: physical and chemical characterization, materials and visibility effects, effects on vegetation, agricultural and forest ecosystem effects, and the health effects of photochemical oxidants. The conference was held in cooperation with EPA, which used the conference as a forum to solicit public opinion regarding standards development.

190

Developed-developing country partnerships: Benefits to developed countries?  

ABSTRACT: Developing countries can generate effective solutions for today's global health challenges. This paper reviews relevant literature to construct the case for international cooperation, and in particular, developed-developing country partnerships. Standard database and web-based searches were conducted for publications in English between 1990 and 2010. Studies containing full or partial data relating to international cooperation between developed and developing countries were retained for further analysis. Of 227 articles retained through initial screening, 65 were included in the final analysis. The results were two-fold: some articles pointed to intangible benefits accrued by developed country partners, but the majority of information pointed to developing country innovations that can potentially inform health systems in developed countries. This information spanned all six WHO health system components. Ten key health areas where developed countries have the most to learn from the developing world were identified and include, rural health service delivery; skills substitution; decentralisation of management; creative problem-solving; education in communicable disease control; innovation in mobile phone use; low technology simulation training; local product manufacture; health financing; and social entrepreneurship. While there are no guarantees that innovations from developing country experiences can effectively transfer to developed countries, combined developed-developing country learning processes can potentially generate effective solutions for global health systems. However, the global pool of knowledge in this area is virgin and further work needs to be undertaken to advance understanding of health innovation diffusion. Even more urgently, a standardized method for reporting partnership benefits is needed-this is perhaps the single most immediate need in planning for, and realizing, the full potential of international cooperation between developed and developing countries. PMID:22709651

191

Identification of pharmaceutical glasses by laser ablation ICP-MS.  

The chemical composition of pharmaceutical glasses (ampoules, infusion bottles, plunger) has been determined by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). A Nd:YAG laser with 10 Hz repetition rate in the Q-switch mode at its fundamental wavelength (1064 nm) was used to identify common types of pharmaceutical glasses. The following isotopes were used for measurements: 7Li, 11B, 23Na, 24Mg, 27Al, 28Si, 29Si, 30Si, 39K, 42Ca, 47Ti, 57Fe, 90Zr, 121Sb, 137Ba. Each analysis included the measurement of 12 craters. Relative standard deviations between 1.8% and 8.0% of the quantitative results were obtained. 29Si was used as internal standard. Standard reference materials (soda-lime-, lead- and borosilicate glasses) were used for external calibration of laser sampling. Linear calibration functions for each isotope were found. All samples and standard materials were digested in a two-step-procedure by nitric/fluoric acid, then measured and externally calibrated by ICP-MS with multi-elemental standard solutions using 45Sc as internal standard. Digestion and laser ablation results agree within 8% (confidential interval 95%) with the certified values. Intensity ratios of most isotopes also agree sufficiently with the corresponding theoretical values (+/- 18%). The developed method allows to distinguish different types of pharmaceutical glasses. PMID:11817168

192

Air kerma standardization for diagnostic radiology, and requirements proposal for calibration laboratories; Padronizacao da grandeza Kerma no ar para radiodiagnostico e proposta de requisitos para laboratorios de calibracao  

The demand for calibration services and quality control in diagnostic radiology has grown in the country since the publication of the governmental regulation 453, issued by the Ministry of Health in 1998. At that time, to produce results facing the new legislation, many laboratories used different standards and radiation qualities, some of which could be inadequate. The international standards neither supplied consistent radiation qualities and standardization for the different types of equipment available. This situation changed with the publication of the new edition of the IEC 61267 standard, published in 2005. A metrology network was created, but it is not yet accredited by the accreditation organism of the country, INMETRO. The objective of this work was to implement the standardization of the air kerma for the un attenuated qualities (RQR) of IEC 61267, and to develop a requirement proposal for instruments calibration laboratories. Results of interlaboratory comparisons demonstrate that the quantity is standardized and internationally traceable. A laboratory requirement proposal was finalized and it shall be submitted to INMETRO to be used as auxiliary normative document in laboratory accreditation. (author)

193

 

INTERNATIONAL STANDARDS FOR PHYTOSANITARY MEASURES (ISPM), PUBLICATION NO. 15 GUIDELINES FOR REGULATING WOOD PACKAGING MATERIAL IN INTERNATIONAL TRADE This standard describes phytosanitary measures to reduce the risk of introduction and/or spread of quarantine pests associated with wood packaging material (including dunnage), made of coniferous and non-coniferous raw wood, in use in international trade

194

ISO 9000: The challenge of Camacari petrochemical complex, Bahia State - Northeast Brazil; ISO 9000: o desafio do polo petroquimico de Camacari, BA, Brazil  

The petrochemical complex of Camacari, BA, Brazil, involves 40 companies, responsible for 55% of brazilian production. The companies were installed using the most modern techniques related to quality available at that time, strongly centered in quality control. The new industrial policy towards reducing import taxes and allowing the entrance of foreign products at competitive prices, besides the quality exigencies of international market, induced the companies to develop new techniques for quality management based in the ISO 9000 standards. The paper shows the stage of implementation of these standards in 30 companies, corresponding to 90% of global sales of all the complex. (author)

195

Astronomical Research Using Virtual Observatories  

The Virtual Observatory (VO) for Astronomy is a framework that empowers astronomical research by providing standard methods to find, access, and utilize astronomical data archives distributed around the world. VO projects in the world have been strenuously developing VO software tools and/or portal systems. Interoperability among VO projects has been achieved with the VO standard protocols defined by the International Virtual Observatory Alliance (IVOA). As a result, VO technologies are now used in obtaining astronomical research results from a huge amount of data. We describe typical examples of astronomical research enabled by the astronomical VO, and describe how the VO technologies are used in the research.   

196

Self-locking polymer-covered nuts for joining elements of chain conveyors  

The VNIIPTuglemash institute developed and tested a new type of self-locking nut for joining links of haulage chains on chain conveyors used for coal haulage in underground mining. Standard nuts used in the USSR are equipped with special plastic inserts on the internal thread. The standard nuts are in short supply and expensive to manufacture. The self-locking nuts tested by the institute are spray coated with polyamides. Tests show that polyamide-coated nuts are superior to self-locking nuts with plastic inserts.

197

The safety of the future hydrogen economy  

Limited operating experience with hydrogen energy systems in consumer environments is recognised as a significant barrier to the implementation of the required infrastructure. Significant international effort has been initiated to develop relevant codes and standards. To prevent emerging codes, standards and local regulations from being unnecessarily restrictive, real operating experience is needed using full-scale experimental trials. This paper begins with an overview of experimental work commissioned by both the regulator and industry to help quantify the hazards and risks. It then summarises work co-funded by the GB regulator and EU on:*Jet releases, barriers to reduce safety distances and self ignition undertaken using high pressure hydrogen compression, storage and release equipment....

198

Simultaneous determination of nine pyrethroids in indoor insecticide products by capillary gas chromatography  

A gas chromatographic method was developed for simultaneous determination of nine pyrethroids (permethrin, transallethrin, beta-cypermethrin, prallethrin, tetramethrin, transfluthrin, cyphenothrin, phenothrin, imiprothrin) in indoor insecticide products using dibutyl phthalate and iso-octyl phthalate as two internal standards. Parameters affecting the extraction and separation efficiency were investigated. Good linear fit curves were obtained in a range of 0.4-900mg/l with correlation coefficients >0.999. The proposed method was successfully applied for the determination of pyrethroids in mosquito coils and two aerosol products. The recovery of transallethrin in mosquito coils at three spiked levels was 96.8% with relative standard deviation less than 2.7%. The recoveries of transallethrin...

199

Inadequacy of von Neumann entropy for characterizing extractable work  

The lack of knowledge that an observer has about a system limits the amount of work it can extract. This lack of knowledge is normally quantified using the Gibbs/von Neumann entropy. We show that this standard approach is, surprisingly, only correct in very specific circumstances. In general, one should use the recently developed smooth entropy approach. For many common physical situations, including large but internally correlated systems, the resulting values for the extractable work can deviate arbitrarily from those suggested by the standard approach.

200

Catching up through the development of technology standard: The case of TD-SCDMA in China  

This paper explored the key factors affecting catching up through technology standard development by studying the evolution of TD-SCDMA, one of the three international standards of 3G mobile communications, in China. It was found that this was a complex co-evolution process between firm strategy and government policy aimed mainly at solving the challenges of late-comer disadvantages. The paper also examined the unique features of this co-evolution process, including the importance of the informal social network of non-customer stakeholders, and discussed the theoretical and practical implications of the key findings.

 
 
 
 
201

A Bat, a Snake, a Cockroach, and a Fuzzhead: Using Children's Literature to Teach about Positive Character Traits  

The authors describe a five-day, literature-based thematic unit for second-graders on positive character traits, such as friendship, respect, perseverance, honesty, and cooperation, and how four books by Janell Cannon are integral to children's learning. (The authors offer suggestions throughout for adapting the unit for younger children.) They address Connecticut's standards for math, science, social-emotional, and cognitive development and NAEYC and IRA (International Reading Association) standards for language arts. The unit included a variety of activities so each child would benefit.

202

Tissue-Mimicking Materials Using Segmented Polyurethane Gel and Their Acoustic Properties  

Accurate testing of an instrument by phantoms requires a tissue-mimicking material that has the acoustic velocity and density defined in the International Electrotechnical Commission (IEC) standard, and furthermore the tissue-mimicking material must be stable over time. To achieve the tissue-mimicking materials with the desired acoustic velocity and density defined in the IEC standard, new materials have been developed. The form of tissue-mimicking materials reported comprised polystyrene and poly(methyl methacrylate) (PMMA) particles dispersed in segmented polyurethane gel. They were stable over a period of 40 days and the changes in weight and acoustic velocity did not exceed 0.5%.

203

Conventional engine technology. Volume 1: Status of OTTO cycle engine technology  

Federally-mandated emissions standards have led to major changes in automotive technology during the last decade. Efforts to satisfy the new standards were directed more toward the use of add-on devices, such as catalytic converters, turbochargers, and improved fuel metering, than toward complete engine redesign. The resulting changes are described and the improvement brought about by them in fuel economy and emissions levels are fully documented. Four specific categories of gasoline-powered internal combustion engines are covered, including subsystem and total engine development. Also included are the results of fuel economy and exhaust emissions tests performed on representative vehicles from each category.

204

Reliability Evaluation Method for the Railway System : A Model for Complicated Dependency  

In the field of international standards such as IEC standards, safety is generally explained with risk. In the risk analysis process, it is a very important task to calculate the reliability of large-scale systems which include equipment and operators. As for the railway risk analysis, there are many cases that conventional techniques, such as event trees (ETs), and fault trees (FTs), which are broadly used as practical tools, can not be applied adequately. This is because, for the railway system, there are a number of subsystems with complicated dependencies. Then, we developed a new network-type reliability evaluation model, Typed State Influence Diagram (TSID), which can explicitly express such a complicated dependency.   

205

MACS as a tool for international inspections  

The MACS/ACRS (Managed Access by Controlled Sensing/Access by Controlled Remote Sensing) system is a collection of communication devices, video capability, and distance-measuring equipment which can effectively substitute for the physical presence of a challenge inspector within a facility. The MACS design allows growth of the prototype, developed in response to the Chemical Weapons Convention (CWC), into a versatile device for inspection of sensitive nuclear facilities under other international arrangements, for example the proposed Fissile Material Cutoff Convention. A MACS/ACRS-type system in a standard, international-recognized configuration could resolve sensitive information and safety concerns through providing a means of achieving the goals of an inspection while excluding the inspector. We believe the technology used to develop MACS for the Defense Nuclear Agency, followed by ACRS for the Department of Energy, is universally adaptable for minimally-intrusive managed-access international inspections of sensitive sites.

206

Device-associated nosocomial infections in limited-resources countries: Findings of the International Nosocomial Infection Control Consortium (INICC)  

Need The rates of health care-associated infections (HAIs) and bacterial resistance in developing countries are 3 to 5 times higher than international standards. HAIs increase length of stay (10 days), costs (US $5000 to US $12,000), and mortality (by a factor of 2 to 3). Organization The International Nosocomial Infection Control Consortium (INICC), founded in 1998, is the only source of aggregated international data on the epidemiology of device-associated infections (DAIs). Its advisory board includes 12 representatives from developed countries, who help guide INICCs activities, and 8 country coordinators. The INICC network has about 5400 active researchers in 98 intensive care units (ICUs) in 18 countries on 4 continents that conduct infection control research and surveillance using st...

207

Application of ISO 9000 Series Quality Management Standards at a Higher Education Institution: A Case of Lithuanian Maritime College  

The European education standards assurance and pursuit of quality in education have been announced as strategic aims of the Lithuanian education system in the light of new challenges the society is facing and opportunities offered by democracy, development of market economy and globalization. One of the ways to achieve the aims mentioned above is the implementation of ISO 9000 ("International Organization for Standardization") series standards in higher education institutions. The key aim of the standards is to recommend for an organization how an efficient quality management system should be developed to encourage through its functioning continual development of an organization. The article overviews specific quality requirements for marine training, the development of ISO series standards is discussed, concepts and structures of contemporary quality management systems based on ISO regulations are analysed. The peculiarities of the application of the standards in a tertiary school are revealed and description of the quality management system and its application experience at the Lithuanian Maritime College is presented. (Contains 2 footnotes, 3 tables, and 8 figures.)

208

Draft of new maintenance standards for LWR in Japan  

Activities of development of new maintenance standards for operating nuclear power plant in Japan are described. The work of drafting the standards has been done by the Committee of Nuclear Plant Operation and Maintenance Standards (POMS), that was organized in the Japan Power Engineering and Inspection Corporation under the entrustment from the Ministry of International Trade and Industry. The articles of ASME Section XI related to inspection, flaw evaluation and repair have been examined and modified, if necessary, so as to introduce latest Japanese database and technological knowledge. In the area of repairs, many repair techniques verified in recent years in Japan were incorporated i n addition to those specified in ASME Section XI. Finally major differences between ASME Section XI and the draft of the standards are listed.

209

The H.264/AVC Advanced Video Coding standard: overview and introduction to the fidelity range extensions  

H.264/MPEG-4 AVC is the latest international video coding standard. It was jointly developed by the Video Coding Experts Group (VCEG) of the ITU-T and the Moving Picture Experts Group (MPEG) of ISO/IEC. It uses state-of-the-art coding tools and provides enhanced coding efficiency for a wide range of applications, including video telephony, video conferencing, TV, storage (DVD and/or hard disk based, especially high-definition DVD), streaming video, digital video authoring, digital cinema, and many others. The work on a new set of extensions to this standard has recently been completed. These extensions, known as the Fidelity Range Extensions (FRExt), provide a number of enhanced capabilities relative to the base specification as approved in the Spring of 2003. In this paper, an overview of this standard is provided, including the highlights of the capabilities of the new FRExt features. Some comparisons with the existing MPEG-2 and MPEG-4 Part 2 standards are also provided.

210

Development of a consensus standard for verification and validation of nuclear system thermal-fluids software  

With the resurgence of nuclear power and increased interest in advanced nuclear reactors as an option to supply abundant energy without the associated greenhouse gas emissions of the more conventional fossil fuel energy sources, there is a need to establish internationally recognized standards for the verification and validation (V&V) of software used to calculate the thermal-hydraulic behavior of advanced reactor designs for both normal operation and hypothetical accident conditions. To address this need, ASME (American Society of Mechanical Engineers) Standards and Certification has established the V&V 30 Committee, under the jurisdiction of the V&V Standards Committee, to develop a consensus standard for verification and validation of software used for design and analysis of advanced re...

211

Developing a strategic framework for the WiBro service in the global market  

This research presents a strategic framework, associated with a standardization strategy, to achieve successful commercialization of the WiBro (brand service name for WiMAX) service on the global market. Although WiBro was the first wireless broadband internet technology in the world to be developed, commercialized and subsequently designated as an international standard, its performance on the global market has been without notable success and no active research is taking place to change this current state. In order to escape from a narrow domestic market and get to launch abroad, it is important to suggest a strategic roadmap with policy supports of a government as well as to introduce the policy for Wibro standardization. This research analyzed the effects of standardization on business...

212

Comparison of calculated data for the flammability and the oxidation potential according to ISO 10156 with experimentally determined values  

The classification of flammable gas mixtures is based on either testing or calculation methods proposed by the revised international standard ISO 10156. This standard is used for classification of physical hazards in Chapters 2.2 and 2.4 of the UN Globally Harmonized System of Classification and Labelling of Chemicals (GHS) and in the UN Recommendations on Transport of Dangerous Goods (TDG). The test methods of flammability and oxidizing potential in this standard were developed by BAM. Earlier versions of this standard are not based on triangular diagrams and on the reference combustible substance ''ethane''. The old material characteristics, especially in case of oxidizing potential, are based mostly on practical experience without any quantifiable test results. First time it is possible...

213

Development of a Combined Standard Additions/Internal Standards Method to Quantify Residual PEG in Ethoxylated Surfactants by MALDI TOFMS  

Measuring the residual polyethylene glycol (PEG) in polyethylene oxide (PEO)-based surfactants is important to fully understanding the performance of these materials. Traditional methods of quantitating PEG in PEO-based surfactants can be time-consuming and struggle with low amounts or overlapping molecular mass distributions. This paper describes a matrix-assisted laser desorption/ionization (MALDI) mass spectrometry method developed to quantitate residual PEG in a series of ethoxylated surfactants. The technique addresses the difficulties faced in doing quantitative MALDI experiments by utilizing both internal standard and standard additions protocols. The method produces excellent straight line standard addition plots, and the quantitative results are verified using both a constructed standard and an independent traditional chromatographic separation.

214

Automated Controlled-Potential Coulometer for the IAEA  

An automated controlled-potential coulometer has been developed at the Savannah River Site (SRS) for the determination of plutonium for use at the International Atomic Energy Agency`s (IAEA) Safeguards Analytical Laboratory in Siebersdorf, Austria. The system is functionally the same as earlier systems built for use at the Savannah River Site`s Analytical Laboratory. All electronic circuits and printed circuits boards have been upgraded with state-of-the-art components. A higher amperage potentiostat with improved control stability has been developed. The system achieves electronic calibration accuracy and linearity of better than 0.01 percent, with a precision and accuracy better than 0.1 percent has been demonstrated. This coulometer features electrical calibration of the integration system, electrolysis current background corrections, and control-potential adjustment capabilities. These capabilities allow application of the system to plutonium measurements without chemical standards, achieving traceability to the international measurement system through electrical standards and Faraday`s constant. the chemist is provided with the capability to perform measurements without depending upon chemical standards, which is a significant advantage for applications such as characterization of primary and secondary standards. Additional benefits include reducing operating cost to procure, prepare and measure calibration standards and the corresponding decrease in radioactive waste generation. The design and documentation of the automated instrument are provided herein. Each individual module`s operation, wiring, layout, and alignment are described. Interconnection of the modules and system calibration are discussed. A complete set of prints and a list of associated parts are included.

215

Sustainable Biomass Potentials for Food-Feed-Fuels in the Future : -How can Biorefinery concepts and Bioenergy fit into a Change made from 100 percent Fossil Dependency Towards a 100 Percent Renewable Energy Future?  

Biomass sources as Woodchips – Wood pellets, Straw – Bio pellets, animal manure, farm-by products and new cropping systems are integrated in our society’s needs. The mindset for shifting from fossil fuels based economies into sustainable energy economies already exist. Bioenergy utilization systems has for many years been forming the basis for the change together with wind and solar energy. These resources still contains great potentials for energy supply chains in increasing areas of Europe and the World. Biomass sustainability issues could be solved by developing the international sustainability criteria. The sustainability criteria agreed internationally could be realized as a tool to secure the positive impacts of bioenergy and to foster the international trade. This study investigates the developments by national and international bodies of biomass standardization and certification systems and analyzes the biomass verification procedure in more detail. Belgium is taken as a case example for analysis. There is a need for action to solve the issues as sustainable bioenergy targeted policy developments, lack of cooperation within industry, governments, standardization bodies, NGO’s and other key stakeholders that stagnate the processes possessed in use of biomass.

216

Report of Official foreign Travel to Spain April 17-29, 1999.  

The Department of Energy (DOE) has moved rapidly toward electronic production, management, and dissemination of scientific and technical information. The World-Wide Web (WWW) has become a primary means of information dissemination. Electronic commerce (EC) is becoming the preferred means of procurement. DOE, like other government agencies, depends on and encourages the use of international standards in data communications. Like most government agencies, DOE has expressed a preference for openly developed standards in preference to proprietary designs promoted as "standards" by vendors. In particular, there is a preference for standards developed by organizations such as the International Organization for Standardization (ISO) and the American National Standards Institute (ANSI) that use open, public processes to develop their standards. Among the most widely adopted international standards is the Standard Generalized Markup Language (SGML, ISO 8879:1986, FIPS 152), which DOE has selected as the basis of its electronic management of documents. Besides the official commitment, which has resulted in several specialized projects, DOE makes heavy use of coding derived from SGML, and its use is likely to increase in the future. Most documents on the WWW are coded in HTML ("Hypertext Markup Language"), which is an application of SGML. The World-Wide Web Consortium (W3C), with the backing of major software houses like Microsoft, Adobe, and Netscape, is promoting XML ("eXtensible Markup Language"), a class of SGML applications, for the future of the WWW and the basis for EC. W3C has announced its intention of discontinuing future development of HTML and replacing it with XHTML, an application of XML. In support of DOE's use of these standards, I have served since 1985 as Chairman of the international committee responsible for SGML and related standards, ISO/IEC JTC1/SC34 (SC34) and its predecessor organizations. During my April 1999 trip, I convened the spring 1999 meeting of SC34 in Granada, Spain. I also attended a major conference on the use of SGML and XML. SC34 maintains and continues to enhance several standards. In addition to SGML, which is the basis of HTML and XML, SC34 also works on the Document Style Semantics and Specification Language (DSSSL), which is the basis for W3C's XSL ("eXtensible Style Language," to be used with XML) and the Hypermedia/Time-based Document Structuring Language (HyTime), which is a major influence on W3C's XLink ("XML Linking Language"). SC34 is also involved in work with ISO's TC184, Industrial Data, on the linking of STEP (the standard for the interchange of product model data) with SGML. In addition to the widespread use of the WWW among DOE's plants and facilities in Oak Ridge and among DOE sites across the nation, there are several SGML-based projects at the Y-12 Plant. My project team in Information Technology Services developed an SGML-based publications system that has been used for several major reports at the Y-12 Plant and Oak Ridge National Laboratory (ORNL). SGML is a component of the Weapons Records Archiving and Preservation (WRAP) project at the Y-12 Plant and is the format for catalog metadata chosen for weapons records by the Nuclear Weapons Information Group (NWIG). Supporting standards development allows DOE and the Y-12 plant both input into the process and the opportunity to benefit from contact with some of the leading experts in the subject matter. Oak Ridge has been for some years the location to which other DOE sites turn for expertise in SGML and related topics.

217

Raster data transfer test using Formtek produced data: MIL-R-28002 Type 1 (Raster)  

The DoD Computer-aided Acquisition and Logistics Support (CALS) Test Network (CTN) is conducting tests of the military standard for the Automated interchange of Technical Information, MIL-STD-1804A, and its companion suite of specifications. The CTN is a DoD sponsored confederation of voluntary participants from industry and government, managed by the Air Force Logistics Command. The primary purpose of the CTN is to evaluate the effectiveness of the CALS standards for technical data interchange and to demonstrate the capability and operational suitability of these standards. To this end, testing should represent the systems and applications in use by a large number of participants. Sampling a wide cross section of industry and government will gain feedback on the various interpretations of the standards and broaden the base of industry participation in the CALS initiative. This test was conducted to allow Formtek to demonstrate their ability to generated a MIL-R-28002 data file. The objective was to evaluate their interpretation of the MIL-R-28002 standard thereby assist the CTN in substantiating the validity of the standards or recommending changes to these standards and the references to national or international standards. Additionally, Quick Short Test Reports (QSTRs) are intended to promote industry and government participation in the CALS initiative, developing a level of confidence in the technology and furthering mission objectives.

218

Benefits to the Simulation Training Community of a New ANSI Standard for the Exchange of Aero Simulation Models  

The American Institute of Aeronautics Astronautics (AIAA) Modeling and Simulation Technical Committee is in final preparation of a new standard for the exchange of flight dynamics models. The standard will become an ANSI standard and is under consideration for submission to ISO for acceptance by the international community. The standard has some aspects that should provide benefits to the simulation training community. Use of the new standard by the training simulation community will reduce development, maintenance and technical refresh investment on each device. Furthermore, it will significantly lower the cost of performing model updates to improve fidelity or expand the envelope of the training device. Higher flight fidelity should result in better transfer of training, a direct benefit to the pilots under instruction. Costs of adopting the standard are minimal and should be paid back within the cost of the first use for that training device. The standard achieves these advantages by making it easier to update the aerodynamic model. It provides a standard format for the model in a custom eXtensible Markup Language (XML) grammar, the Dynamic Aerospace Vehicle Exchange Markup Language (DAVE-ML). It employs an existing XML grammar, MathML, to describe the aerodynamic model in an input data file, eliminating the requirement for actual software compilation. The major components of the aero model become simply an input data file, and updates are simply new XML input files. It includes naming and axis system conventions to further simplify the exchange of information.

219

Spaceborne clock system: Some alternatives for a proposed NASA experiment  

A spaceborne clock experiment is proposed with the objectives of improving international time and frequency comparisons, studying precise one-way Doppler tracking and one-way ranging techniques, performing relativistic studies, and developing new atomic frequency standards technology. Various alternatives are considered for accomplishing these goals, including the use of existing satellite and earth-based time dissemination systems as well as the development of a new frequency standard for this specific application. One conclusion is that several attractive alternatives already exist for meeting the goal of improved time and frequency dissemination. However, to achieve all the other 4 goals at the NASA-stated levels of accuracy, a spaceborne atomic frequency standard may be required. An analysis of achievements to date with quartz oscillators, rubidium standards, cesium beam standards, hydrogen masers, and several other possibilities leads to the conclusion that cesium and rubidium standards offer the best choices for the experiment as proposed by NASA. The greatest obstacle to a spaceborne atomic standard appears to be its electrical power requirements.

220

Vitamin D status as an international issue: national surveys and the problem of standardization.  

Wide spread variation in measurement results of total 25-hydroxyvitamin D (25(OH)D) confounds international efforts to develop evidence-based clinical guidelines. Accordingly, NIH Office of Dietary Supplements (ODS) in collaboration with CDC National Center for Environmental Health (NCEH), National Institute of Standards and Technology (NIST) and Ghent University established the Vitamin D Standardization Program (VDSP) in November 2010. VDSP objectives include: (1) standardize 25(OH)D concentration measurements in national health surveys around the world, (2) evaluate survey differences, (3) extend standardization efforts to assay manufacturers, and to clinical, commercial, and research laboratories, (4) promote standardization of emerging metabolites of vitamin D status, and (5) enable the use of standardized data in patient care and public health. An interlaboratory comparison study is being conducted to assess measurement variability among current assays. Participants include national health surveys from Australia, Canada, Germany, Ireland, Mexico, South Korea, UK and USA, 15 assay manufacturers, and two external quality assurance programs. CDC will implement a formal laboratory certification program. Standardization activities will use single-donor, fresh-frozen serum collected using the CLSI C37 protocol. Initial assay performance criteria, based on biological variability data, are ? 10 % imprecision and ? 5 % bias in relation to the reference values. An ancillary study on commutability of NIST SRM 972a, external quality assurance testing materials is included. To increase the comparability of existing data from different national surveys, master equations will be developed to facilitate the conversion of already existing national survey data to the NIST-Ghent University reference measurement procedures. PMID:22536760

 
 
 
 
221

The Management of Innovation and Patterns in Technological Development  

This paper is a review of efforts to summarise long-term technological development in the management literature in terms of 'paths' or trajectories. They are most useful as a way of understanding the general search for economies of scale, but the management value of such ideas is compromised because it is difficult in practice to judge the beginning and end of such patterns of change. The establishment of technolgical standards is seen as a special case of such patterns within technological development. the classic cases of the QWERTY keyboard, the VHS versus Betamax videocassette recorder standard and the international choice of colour TV broadcasting standard show that the most difficult management problems occur when there is no clear economic or use-value attached to one standard amongst many (this follows if Liebowitz and Margolis' revision of the first two cases is accepted): when there is a choice between various 'neutral' standards. In such circumstances a blatant attempt to use a particular standard to benefit one technological player against others, when the others have equivalent technological ability, is likely to trigger mutually destructive game-playing, as occurred in the colour TV standards case.

222

Have the auditors closed the expectation gap concerning evaluation of internal control?  

In the last decades the focus on expectation gap issues has resolved many fundamental discrepancies between best-practice standards and the expectations stated by the primary users of audit services. Maybe the most important discrepancy has been between the view on internal control as formulated in the auditing standards and the concept of internal control as understood by company management. In the US, this was realized in the Treadway report on fraudulent financial reporting, which stated the need for at common reference point on the content of internal control. Since this need was explicitly stated in the late eighties, the Committee of Sponsoring Organizations of the Treadway Commission decided to develop an integrated framework on internal control. The resulting attempt to provide a framework was published in the COSO-report in 1992. Although the primary scope of this report was a message concerning internal controls intended for management directors, it provides a framework which explicitly deals with the interests of all parties involved (including auditors, board of directors and regulating bodies). The auditors took this into account by updating the particular auditing standard on internal control (the replacement of SAS 55 with SAS 78 "Consideration of the Internal Control Structure in a Financial Statement Audit"). The purpose of this paper is to examine to what extent realized discrepancies has been narrowed in, or completely resolved, by the joint efforts from COSO and the standard setters. Realized discrepancies are identified and related to the necessary features of an integrated framework. The necessary features include (1) the definition of internal controls, (2) the components of internal control, (3) the criteria for evaluating internal control as stated by the auditors (4) the criteria for evaluating internal controls as stated by management, and (5) the integration of internal control evaluations from management and auditors. The paper provides evidence from an in-depth contents analysis comparing SAS No. 55 from 1988 with the COSO-report from 1992 and SAS No. 78 from 1995. The analysis is a longitudinal approach used on these essential documents, which represent the promulgation of best practice in the area in the United States. Each of the features is examined in turn in order to assess the contribution to an overall framework of internal control. Overall, the findings suggest that the auditors have not made the needed effort to close a realized expectation gap. One perspective of these findings can be related to the need for future regulation initiatives. An integrated framework should integrate the auditor, that is, the auditor has to disclose the extent of internal control evaluations in light of the expectations from the primary users, namely that they always conduct such evaluations. The conclusion is that a major discrepancy still needs to be resolved. Another perspective is to avoid an exact replication of the described efforts to close the realized expectation gaps as performed by othernational (European) practices in the standard setting efforts concerning internal control

223

Report of official foreign travel to France, June 7--20, 2000  

The Department of Energy (DOE) has moved rapidly toward electronic production, management, and dissemination of scientific and technical information. The World-Wide Web (WWW) has become a primary means of information dissemination. Electronic commerce (EC) is becoming the preferred means of procurement. DOE, like other government agencies, depends on and encourages the use of international standards in data communications. Like most government agencies, DOE has expressed a preference for openly developed standards over proprietary designs promoted as ``standards'' by vendors. In particular, there is a preference for standards developed by organizations such as the International Organization for Standardization (ISO) and the American National Standards Institute (ANSI) that use open, public processes to develop their standards. Among the most widely adopted international standards is the Standard Generalized Markup Language (SGML, ISO 8879:1986, FIPS 152), to which DOE long ago made a commitment. Besides the official commitment, which has resulted in several specialized projects, DOE makes heavy use of coding derived from SGML: Most documents on the WWW are coded in HTML (Hypertext Markup Language), which is an application of SGML. The World-Wide Web Consortium (W3C), with the backing of major software houses like Adobe, IBM, Microsoft, Netscape, Oracle, and Sun, is promoting XML (eXtensible Markup Language), a class of SGML applications, for the future of the WWW and the basis for EC. In support of DOE's use of these standards, the authors has served since 1985 as Chairman of the international committee responsible for SGML and related standards, ISO/IEC JTC1/SC34 (SC34) and its predecessor organizations. During his June 2000 trip, he chaired the spring 2000 meeting of SC34 in Paris, France. He also attended a major conference on the use of SGML and XML and led a meeting of the International SGML/XML Users' Group (ISUG). In addition to the widespread use of the WWW among DOE's plants and facilities in Oak Ridge and among DOE sites across the nation, there are several SGML-based projects at the Oak Ridge Y-12 Plant. The local project team developed an SGML-based publications system that has been used for several major reports at the Y-12 Plant and Oak Ridge National Laboratory (ORNL). SGML is a component of the Weapons Records Archiving and Preservation (WRAP) project at the Y-12 Plant and is the format for catalog metadata chosen for weapons records by the Nuclear Weapons Information Group (NWIG). The Ferret system for automated classification analysis will use XML to structure its knowledge base. Supporting standards development allows DOE and the Y-12 plant the opportunity both to provide input into the process and to benefit from contact with some of the leading experts in the subject matter. Oak Ridge has been for some years the location to which other DOE sites turn for expertise in SGML and related topics.

224

Stabilizing knowledge through standards - A perspective for the humanities  

It is usual to consider that standards generate mixed feelings among scientists. They are often seen as not really reflecting the state of the art in a given domain and a hindrance to scientific creativity. Still, scientists should theoretically be at the best place to bring their expertise into standard developments, being even more neutral on issues that may typically be related to competing industrial interests. Even if it could be thought of as even more complex to think about developping standards in the humanities, we will show how this can be made feasible through the experience gained both within the Text Encoding Initiative consortium and the International Organisation for Standardisation. By taking the specific case of lexical resources, we will try to show how this brings about new ideas for designing future research infrastructures in the human and social sciences.

225

Comparison of ISO Standards for Device Performance; 20072 and 27427: A Critical Appraisal  

Abstract Two separate international standards, ISO 20072:2009 and ISO 27427:2010, have recently been published that relate to the development and performance testing of oral inhaled products (OIPs). The scope of ISO 20072 encompasses all OIP forms except nebulizing systems, whereas ISO 27427 was developed specifically for this class of OIP. Compliance with these standards will likely be necessary for manufacturers seeking approval to market inhaler devices in the European Union (EU). Their adoption in the United States may take a considerable time, but the FDA has expressed support in general terms for the ISO process. Key aspects of both standards that are very different in style and content are identified and discussed from the perspective of a potential user. In the approach adopted by ...

226

Towards richer descriptions of our collection of genomes andmetagenomes  

In this commentary, we advocate building a richer set of descriptions about our invaluable and exponentially growing collection of genomes and metagenomic datasets through the construction of consensus-driven data capture and exchange mechanisms. Standardization activities must proceed within the auspices of open-access and international working bodies, and to tackle the issues surrounding the development of better descriptions of genomic investigations we have formed the Genomic Standards Consortium (GSC). Here, we introduce the 'Minimum Information about a Genome Sequence' specification in the hopes of gaining wider participation in its development and discuss the resources that will be required to support it (standardization of annotations through the use of ontologies and mechanisms of metadata capture, exchange). As part of its wider goals, the GSC also strongly supports improving the 'transparency' of the information contained in existing genomic databases that contain calculated analyses and genomic annotations.

227

Mapping global health research investments, time for new thinking - A Babel Fish for research data.  

ABSTRACT: Today we have an incomplete picture of how much the world is spending on health and disease-related research and development (R&D). As such it is difficult to align, or even begin to coordinate, health R&D investments with international public health priorities.Current efforts to track and map global health research investments are complex, resource-intensive, and caveat-laden. An ideal situation would be for all research funding to be classified using a set of common standards and definitions. However, the adoption of such a standard by everyone is not a realistic, pragmatic or even necessary goal.It is time for new thinking informed by the innovations in automated online translation - e.g. Yahoo's Babel Fish. We propose a feasibility study to develop a system that can translate and map the diverse research classification systems into a common standard, allowing the targeting of scarce research investments to where they are needed most. PMID:22938160

228

Development of optical instrument as turbidimeter: a comparative study  

Purpose - The purpose of this paper is to present a comparative study between two low-cost turbidimeter designs using a multi purpose Optical Fiber NIR System (OF-NIRS), Optical Fiber NIR System-Modified (OF-NIRS-M) and High Sensitivity NIR System (HS-NIRS) conducted in the development of a turbidimeter by closely replicating the existing standard design guideline. Optical method is a typical measuring technique that has been applied intensively for the measurement of water turbidity. Design/methodology/approach - Comprehensive guidelines for the development of turbidimeter have been stated by the United States Environmental Protection Agency (EPA Method 180.1) and the International Organization for Standardization (ISO 7027) and have been used as standards by instrument's manufacturers wo...

229

International Experience in Standards and Labeling Programs for Rice Cookers  

China has had an active program on energy efficiency standards for household appliances since the mid-1990s. Rice cooker is among the first to be subject to such mandatory regulation, since it is one of the most prevalent electric appliances in Chinese households. Since first introduced in 1989, the minimum energy efficiency standard for rice cookers has not been revised. Therefore, the potential for energy saving is considerable. Initial analysis from CNIS indicates that potential carbon savings is likely to reach 7.6 million tons of CO2 by the 10th year of the standard implementation. Since September 2007, CNIS has been working with various groups to develop the new standard for rice cookers. With The Energy Foundation's support, LBNL has assisted CNIS in the revision of the minimum energy efficiency standard for rice cookers that is expected to be effective in 2009. Specifically, work has been in the following areas: assistance in developing consumer survey on usage pattern of rice cookers, review of international standards, review of international test procedures, comparison of the international standards and test procedures, and assessment of technical options of reducing energy use. This report particularly summarizes the findings of reviewing international standards and technical options of reducing energy consumption. The report consists of an overview of rice cooker standards and labeling programs and testing procedures in Hong Kong, South Korea, Japan and Thailand, and Japan's case study in developing energy efficiency rice cooker technologies and rice cooker efficiency programs. The results from the analysis can be summarized as the follows: Hong Kong has a Voluntary Energy Efficiency Labeling scheme for electric rice cookers initiated in 2001, with revision implemented in 2007; South Korea has both MEPS and Mandatory Energy Efficiency Label targeting the same category of rice cookers as Hong Kong; Thailand's voluntary endorsement labeling program is similar to Hong Kong in program design but has 5 efficiency grades; Japan's program is distinct in its adoption of the 'Top Runner' approach, in which, the future efficiency standards is set based on the efficiency levels of the most efficient product in the current domestic market. Although the standards are voluntary, penalties can still be evoked if the average efficiency target is not met. Both Hong Kong and South Korea's tests involve pouring water into the inner pot equal to 80% of its rated volume; however, white rice is used as a load for its tests in Hong Kong whereas no rice is used for tests in South Korea. In Japan's case, water level specified by the manufactures is used and milled rice is used as a load only partially in the tests. Moreover, Japan does not conduct heat efficiency test but its energy consumption measurements tests are much more complex, with 4 different tests are conducted to determine the annual average energy consumption. Hong Kong and Thailand both set Minimum Allowable Heat Efficiency for different rated wattages. The energy efficiency requirements are identical except that the minimum heat efficiency in Thailand is 1 percentage point higher for all rated power categories. In South Korea, MEPS and label's energy efficiency grades are determined by the rice cooker's Rated Energy Efficiency for induction, non-induction, pressure, nonpressure rice cookers. Japan's target standard values are set for electromagnetic induction heating products and non-electromagnetic induction heating products by different size of rice cookers. Specific formulas are used by type and size depending on the mass of water evaporation of the rice cookers. Japan has been the leading country in technology development of various types of rice cookers, and developed concrete energy efficiency standards for rice cookers. However, as consumers in Japan emphasize the deliciousness of cooked rice over other factors, many types of models were developed to improve the taste of cooked rice. Nonetheless, the efficie

230

From 2G TO 3G The Evolution of International Cellular Standards  

The purpose of this paper is to examine the major factors surrouding and contributing to the creation (and success) of Europe's 2nd generation 'GSM' cellular system, and compare and contrast it to key events and recent developments in 3rd generation 'IMT-2000' systems. The objective is to ascertain whether lessons from the development of one system can be applied to the other, and what implications 2G has for the development and assessment of 3G technologies. Among the major themes incorporated into this assessment is the concept of cooperation, and its role in bringing about the collaboration and integration necessary to support the success of an international cellular standard.

231

Evidence-based analysis of physical therapy in Parkinsons disease with recommendations for practice and research  

Physical therapy is often prescribed in Parkinsons disease. To facilitate the uniformity and efficacy of this intervention, we analyzed current evidence and developed practice recommendations. We carried out an evidence-based literature review. The results were supplemented with clinical expertise and patient values and translated into practice recommendations, developed according to international standards for guideline development. A systematic literature search yielded 6 systematic reviews and 23 randomized controlled trials of moderate methodological quality with sufficient data. Six specific core areas for physical therapy were identified: transfers, posture, reaching and grasping, balance, gait, and physical capacity. We extracted four specific treatment recommendations that were bas...

232

Commonwealth and global development: contributions to private transnational governance?  

Inter- and non-governmental anglophone Commonwealths have advocated democracy and development in both formal and informal networks, symbolised by their provision of five of the first chairs of the counter-conflict diamonds Kimberley Process. Given the character of civil society-corporate as well as state-economy relations throughout the Commonwealths, they have been central to the definition and development of standard-setting norms and agencies through extensive heterogeneous coalitions such as the International Campaign to Ban Landmines. Klaus Dingwerth has recently characterised such certification, compacts, processes as 'private transnational governance'. This paper analyses the roles of the Commonwealths in advancing such 'global governance' through the Small Island Developing States ...

233

IEC steps up work on power transformers  

The technical committees of the International Electrotechnical Committee (IEC) play an important part in preparing international standards. In this report the chairman of the Technical Comittee 14 (Power Transformers) describes the present state and the progressive work.

234

ISDS National Center of the Deutsche Bibliotek.  

The ISDS National Center of the Deutsche Bibliothek is outlined. The structure, function and purpose of the international Standard Serial Number (ISSN), and the conception, organization, and working method of the International Serials Data System (ISDS) a...

235

A record of morbidity and medical request profiles in international humanitarian aid, taking the earthquake in Bam in Iran in 2003 as an example  

Abstract Objective With the humanitarian work of the International Red Cross after the earthquake in Bam, Iran, it should be noted that international and national cooperation is possible according to recognised standards and conce...

236

International Reference Ionosphere 2000  

Abstract. The International Reference Ionosphere (IRI) is the international standard for the ... description of the low-latitude bottomside thickness, (2) inclusion of a model for storm-time ..... and modeled B,, values for day and night for a winter ...

237

Development of departmental standard for traceability of measured activity for I-131 therapy capsules used in nuclear medicine  

International Basic Safety Standards (International Atomic Energy Agency, IAEA) provide guidance levels for diagnostic procedures in nuclear medicine indicating the maximum usual activity for various diagnostic tests in terms of activities of injected radioactive formulations. An accuracy of ± 10% i...

238

Thermospray mass spectrometer as a quantitative specific, sensitive, detector for liquid chromatography. Its application to the analysis of pyridostigmine in human plasma.  

A thermospray interface between a HPLC system and a mass spectrometer has been used to develop an assay for pyridostigmine bromide measuring plasma concentrations down to 1 ng ml-1 on a routine basis. Plasma is loaded onto an AASP reversed-phase cartridge, injected onto a HPLC system connected to a Finnigan 4500 mass spectrometer via a thermospray interface and the molecular ion monitored. A deuterated internal standard is used, but calculations with and without the internal standard show its use does not materially improve the quantitation. The precision and accuracy at the limit of quantitation is less than +/- 5% and 95-105%, respectively. The method is used to analyse samples from a bioavailability study by fully automated unattended overnight sample analysis. PMID:2100621

239

Development and Validation of an LC–ESI-MS Method for Quantitative Determination of Aripiprazole in Human Plasma and an Application to Pharmacokinetic Study  

A selective, sensitive, high pressure liquid chromatography–positive electrospray ionization tandem mass spectrometry method was developed and validated for the quantification of aripiprazole in human K2EDTA plasma using zolpidem tartrate as an internal standard. The analyte and internal standard were extracted from human plasma by solid-phase extraction using methanol. The eluted samples were chromatographed on a Grace Smart RP 18 4.6 × 100 mm, 3 µ column by using a 95:5 v/v mixture of methanol and ammonium acetate buffer (30 mM, pH 5.0 ± 0.05) as a gradient mobile phase at a flow rate of 0.6 mL/min, and analyzed by mass spectrometry in the multiple reaction monitoring mode using the [M + H]+ ions m/z 448.03 ? 285.14 for aripiprazole and m/...

240

Replacing Immunoassays for Mephedrone, Ketamines and Six Amphetamine-Type Stimulants with Flow Injection Analysis Tandem Mass Spectrometry  

A screening procedure was developed for the simultaneous detection of mephedrone, six amphetamine-type stimulants (ATS), ketamine and its two metabolites with electrospray ionization flow injection analysis tandem mass spectrometry (FIA–MS-MS). Urine samples were fortified with deuterated analogues as internal standards, extracted with ethyl acetate and analyzed with FIA–MS-MS. The mass analyzer was operated in multiple reaction monitoring mode. Two product ions were monitored for each drug and internal standards. For each analyte, the limit of detection was less than 4 µg/L, within-day and between-day precisions (percent coefficient of variation) at three different concentrations were less than 7.3% and bias was between –17.3 and 11.8%. Total anal...

 
 
 
 
241

Liquid chromatography tandem mass spectrometry method for determination of bisoprolol in human plasma using d5-bisoprolol as the internal standard.  

A simple, reliable and sensitive liquid chromatography tandem mass spectrometry (LC-MS/MS) protocol was developed and validated for quantification of bisoprolol in human plasma. The sample was pretreated with a simple procedure of protein precipitation and an isotope-labeled d5-bisoprolol was used as internal standard. The chromatographic separation was performed on a Capcell Pak C(18) MG III column (100 mm x 2.0 mm, 5 microm). The protonated ion of the analyte was detected in positive ionization by multiple reaction monitoring mode. The mass transition pairs of m/z 326.3 --> 116.3 and m/z 331.3 --> 121.3 were used to detect bisoprolol and the internal standard, respectively. Linearity, accuracy, precision, recovery, matrix effect, dilution test and stability were evaluated during method validation over the range of 0.5-100 ng/mL. The validated method was successfully applied to analyze human plasma samples in a bisoprolol bioavailability study. PMID:19810009

242

Report on the fiscal 1996 result of the research on the promotion scheme toward establishment of an international cooperation system for development of welfare equipment; 1996 nendo chosa hokokusho fukushi yogu kaihatsunado no kokusai kyoryoku taisei kakuritsu ni mukete no suishin hosaku no kento  

In order to support the progress and international activity of a Japanese welfare industry, research was made on a concrete approach to establishment of a Japanese international cooperation system on the basis of the activity trend of welfare organizations and groups in North European countries and Japan. Introduction of standards and a mark system for welfare equipment is under investigation in North European countries, and movement for unified standards is also becoming active among these countries. TIDE project called socioeconomic integrated engineering already exists for handicapped and aged persons in Europe, while a rehabilitation act was enforced in the U.S.A. in 1973. Japan participated in ISO and IEC for promotion of a welfare equipment industry. Rehabilitation Engineering Society of Japan (RESJA) for equipment development and technical support, and Japan Wellness and Welfare Industry Association (JWA) for promotion of the related industries were also established. In Europe, North America and Australia, rehabilitation engineering associations are already in action. 8 figs., 17 tabs.

243

Quantification of captopril in urine through surface-assisted laser desorption/ionization mass spectrometry using 4-mercaptobenzoic acid-capped gold nanoparticles as an internal standard.  

We have developed a new internal standard method for the determination of the concentration of captopril (CAP) through surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) using gold nanoparticles (Au NPs). This approach provided linearity for CAP over the concentration range 2.5-25 microM (R(2) = 0.987), with a limit of detection (signal-to-noise ratio = 3) of 1.0 microM. The spot-to-spot variations in the concentration of CAP through SALDI-MS analyses performed in the absence and presence of the internal standard were 26% and 9%, respectively (15 measurements). This approach provides simplicity, accuracy, precision, and great reproducibility to the determination of the levels of CAP in human urine samples. PMID:20171117

244

Quantification of Captopril in Urine Through Surface-Assisted Laser Desorption/Ionization Mass Spectrometry Using 4-Mercaptobenzoic Acid-Capped Gold Nanoparticles as an Internal Standard  

We have developed a new internal standard method for the determination of the concentration of captopril (CAP) through surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) using gold nanoparticles (Au NPs). This approach provided linearity for CAP over the concentration range 2.5–25 ?M (R2 = 0.987), with a limit of detection (signal-to-noise ratio = 3) of 1.0 ?M. The spot-to-spot variations in the concentration of CAP through SALDI-MS analyses performed in the absence and presence of the internal standard were 26% and 9%, respectively (15 measurements). This approach provides simplicity, accuracy, precision, and great reproducibility to the determination of the levels of CAP in human urine samples.

245

Development of an Ion-Pair HPLC Method for Determination of Acebutolol in Pharmaceuticals  

A simple and accurate ion-pair reversed-phase high-performance liquid chromatographic (RP-HPLC) method has been developed and validated for determination of acebutolol (ACE) in tablet dosage forms. Both ACE and ambroxol (internal standard) were well separated using a reversed phase column and a mobile phase consisting of a mixture of methanol-0.05 M acetic acid (containing 8 mM sodium 1-heptanesulfanate) (65:35 v/v) with pH adjusted to 3.2 with triethylamine. The mobile phase was pumped at 0.80 mL min-1 flow rate and ACE was detected by diode-array detection at 240 nm. The retention times for ACE and internal standard (IS) were 4.574 and 8.236 min, respectively. A linear response (r = 0.9998) was observed in the range of 0.27-2.93 ?g mL-1 in mo...

246

Quantitative determination of volatile organic compounds (VOC) in milk by multiple dynamic headspace extraction and GC-MS.  

A method for the accurate determination of volatile organic compounds (VOC) in milk samples has been developed and tested. It combines multiple dynamic headspace extraction with GC-MS. Absolute amounts of VOC in the liquid phase are obtained by determining the first order kinetic dependence of the stepwise extraction of the analytes and internal standards from the liquid matrix. Compounds released from milk were collected on a train of traps filled with different solid sorbents to cover all components having a number of carbon atoms ranging from 4 to 15. They were analysed by GC-MS after thermal desorption of VOC from the collecting traps. Quantification of VOC in milk was performed using deuterated compounds as internal standards. The method was used to follow seasonal variations of monoterpenes in goat milk and to detect the impact of air pollution on the quality of milk. PMID:15506617

247

Design for risk control: The role of usability engineering in the management of use-related risks  

The majority of medical device incident reports can primarily be attributed to use error. Greater attention to human factors and usability during development of a medical device could improve this situation. However, recent studies have shown that companies do not find the application of a sound usability engineering process according to international standards a simple task. The purpose of this collaborative research project between a medical device company, two universities and a university hospital was to study the practical application of the International Standard for Application of Usability Engineering to Medical Devices, IEC 62366, by means of a case study in industrial practice. This paper describes the user studies in the case and reveals the factors important to success. Also, t...

248

Cyanide quantification in post-mortem biological matrices by headspace GC-MS  

Cyanide is a powerful chemical asphyxiant found in some forensic cases following voluntary (suicide) or involuntary ingestion (fire, accidental exposure). A quantification method for cyanide that is specifically suited to post-mortem forensic purposes was developed. Determination was performed by headspace gas chromatography coupled to mass spectrometry using a GS-GASPRO column on an HP-6890 gas chromatograph with an HP-5973N mass detector. The biological sample was treated with an internal standard, frozen, glacial acetic acid was added and the sample was then incubated at 60^oC for 15min. The headspace was sampled with a disposable syringe, and analyzed to quantify hydrogen cyanide. Isotopically labeled cyanide (^1^3C^1^5N) was used as the internal standard to minimize matrix effect and ...

249

Decabromodiphenyl ether in indoor dust from different microenvironments in a university in the Philippines  

This study was conducted to develop a method for the determination of decabromodiphenyl ether (BDE-209) in indoor dust from different microenvironments in a university in the Philippines. BDE-209 was extracted from dust samples by ultrasonication and determined by HPLC-UV. The determination was performed using external calibration and internal standard calibration. Internal standard calibration was shown to be more precise and sensitive than external calibration. The linearity for the concentration range of 0-300mgL-1 BDE-209 was good (R2=0.993). The % absolute recovery and the % RSD for n=8 spiked dust analysis based on a 0.2g dust sample was 57% and 19%, respectively. The method detection limit was 285ngg-1. All dust samples showed detectable levels of BDE-209 with some at levels below t...

250

Life Cycle Assessment and Carbon Footprint in the Wine Supply-Chain  

Global warming represents one of the most critical internationally perceived environmental issues. The growing, and increasingly global, wine sector is one of the industries which is under increasing pressure to adopt approaches for environmental assessment and reporting of product-related greenhouse gas emissions. The International Organization for Vine and Wine has recently recognized the need to develop a standard and objective methodology and a related tool for calculating carbon footprint (CF). This study applied this tool to a wine previously analyzed using the life cycle assessment (LCA) methodology. The objective was to test the tool as regards both its potential and possible limitations, and thus to assess its suitability as a standard tool. Despite the tool?s user-friendliness, a...

251

Quantitative determination and pharmacokinetic study of casticin in rat plasma by liquid chromatography-mass spectrometry  

A specific and sensitive liquid chromatography-mass spectrometry method has been developed and validated for identification and quantification of casticin in rat plasma after oral and intravenous administrations. Kaempferol was employed as an internal standard (IS). Liquid-liquid extraction using dichloromethane was applied to extract the casticin and the internal standard from plasma. Chromatographic separation was achieved on a Zorbax SB C18 column (100mmx3.0mm, i.d.: 3.5mm) with a mobile phase of methanol: 0.05% formic acid aqueous solution (60:40, v/v) at a flow rate of 0.4mL/min for 10min. The detection was performed by selected ion monitoring (SIM) mode via positive electrospray ionization (ESI) interface. The lower limit of detection (LLOD) was 7ng/mL (S/N=5). The calibration curves...

252

Le Redoublement à L'école: Une Maladie Universelle?  

In France, despite efforts on the part of the authorities, grade repetition continues to be practised in schools. Internationally, there is a great diversity of pratice in this area, both in Europe and in the rest of the world. In European countries that use repetition, such as Belgium, France and Switerland, teachers affirm their confidence in the positive results of the practice. Much research, however, indicates that repetition is not beneficial to the pupil concerned. Furthermore, it is possible, using standardized tests developed by the International Association for the Evaluation of Educational Achievement, to demonstrate that countries which have abandoned grade repetition have not suffered a lowering of educational standards, nor have they incurred extra costs. One way to reduce the need for repetition would be to give teachers better information on the real potentialities of each pupil, thus helping them to practice a more individualized form of pedagogy.

253

[Application of internal standard to analysis of the metal Ni element in soils by X-ray fluorescence spectroscopy].  

We quantitatively analyzed the content of the element Ni in the national standard soil samples by the method of X-ray fluorescence spectroscopy through using EDXRF metal experimental platform in ambient environment of the laboratory. Studying the characteristics of X-ray fluorescence of element Ni in the experiment, the calibration curve of element Ni was measured by using the adding internal standard method and the method of how to select the internal standard element was analysed according to the experimental results. The experimental results demonstrate that the matrix suitable element can be selected as the internal standard element to analyse the soil samples; using Pb L(alpha) line, Cu, Fe and K(alpha) lines as internal standard lines, the relative deviation of element from the standard value is 6.24%, 5.24% and 5.22%, which indicates that selecting the appropriate characteristic line of the matrix major element as the internal standard line can effectively improve measurement accuracy of the results. PMID:22715799

254

Study on international publicity and export strategy establishment of nuclear technology  

The objective of this study is to devise a proper measure for international publicity and technology export strategy. Analysed and summaries in detail are other countries nuclear policy trend and the current technology development status of Korea Standard Nuclear Plant that we developed on our own technology, design and construction technology for research reactor, System-integrated Modular Advanced Reactor of which design is in progress, Direct use of Spent PWR Fuel in CANDU Reactors, and Radioisotopes. Based on that, the measures are proposed for the export industrialization of nuclear technology and establishment of the export basis. Also the international nuclear cooperation and publicity strategy are suggested to support the technology export basis. By surveying the world nuclear status, the direction for the international cooperation and publicity is settled and the specific publicity strategy is proposed for the cooperation with IAEA and multi-countries and the establishment of the nuclear technology export basis. As part of this project, the panel on major technologies such as Korea Standard Nuclear Plant, HANARO, and System-integrated Modular Advanced Reactor was displayed successfully at the IAEA meeting, which contribute much to the publicity of our nuclear technology to the international nuclear society. (author)

255

New radiation warning sign  

Full text: Radiation accidents involving orphan radioactive sources have happened as a result of people not recognizing the radiation trefoil symbol or from being illiterate and not understanding a warning statement on the radiation source. The trefoil symbol has no inherent meaning to people that have not been instructed in its use. A new radiation warning sign, to supplement the existing trefoil symbol, has been developed to address these issues. Human Factors experts, United Nations member states, and members of the international community of radiation protection professionals were consulted for input on the design of a new radiation warning sign that would clearly convey the message of 'Danger- Run Away- Stay Away' when in close proximity to a dangerous source of radiation. Cultural differences of perception on various warning symbols were taken into consideration and arrays of possible signs were developed. The signs were initially tested in international children for identification with the desired message and response. Based on these test results and further input from radiation protection professionals, five warning signs were identified as the most successful in conveying the desired message and response. These five signs were tested internationally in eleven countries by a professional survey company to determine the best sign for this purpose. The conclusion of the international testing is presented. The new radiation warning sign is currently a draft ISO standard under committee review. The design of the propose d radiation warning sign and the proposed implementation strategy outlined in the draft ISO standard is presented. (authors)

256

Marketing capabilities: do they matter in INVs?  

This paper examines the influence that marketing capabilities developed in international new ventures can have on their international performance and international geographical diversification. Rapid entry in foreign markets is also highlighted as a factor contributing to the development of marketin...

257

Common Core State Standards for English Language Arts & Literacy in History/Social Studies, Science, and Technical Subjects  

The Common Core State Standards for English Language Arts & Literacy in History/Social Studies, Science, and Technical Subjects ("the Standards") are the culmination of an extended, broad-based effort to fulfill the charge issued by the states to create the next generation of K-12 standards in order to help ensure that all students are college and career ready in literacy no later than the end of high school. The present work, led by the Council of Chief State School Officers (CCSSO) and the National Governors Association (NGA), builds on the foundation laid by states in their decades-long work on crafting high-quality education standards. The Standards also draw on the most important international models as well as research and input from numerous sources, including state departments of education, scholars, assessment developers, professional organizations, educators from kindergarten through college, and parents, students, and other members of the public. In their design and content, refined through successive drafts and numerous rounds of feedback, the Standards represent a synthesis of the best elements of standards-related work to date and an important advance over that previous work. (Contains 2 footnotes.) [For appendixes to this report, see: (1) "Common Core State Standards for English Language Arts & Literacy in History/Social Studies, Science, and Technical Subjects. Appendix A: Research Supporting Key Elements of the Standards, Glossary of Key Terms" (ED522007); (2) "Common Core State Standards for English Language Arts & Literacy in History/Social Studies, Science, and Technical Subjects. Appendix B: Text Exemplars and Sample Performance Tasks" (ED522010); and (3) "Common Core State Standards for English Language Arts & Literacy in History/Social Studies, Science, and Technical Subjects. Appendix C: Samples of Student Writing" (ED522009).

258

Report on results 1998. Standardization of test measuring method of fine ceramics for communication equipment; 1998 nendo seika hokokusho. Tsushin kikiyo fine ceramics no shiken hyoka hoho no hyojunka  

Technological development is in progress at present for the intelligent transport system for example that uses a microwave frequency range of 60GHz or 90GHz toward the practical use, with a demand increasing for measuring the electrical properties of fine ceramics (FC) to be used in the communication equipment of the system. The measuring method in the microwave frequency range of 30GHz or less is about to be standardized in IEC TC49/WG10; however, the method above 30GHz has not yet been examined for the standardization internationally. The subject research is intended to establish the method of measuring electrical properties such as the dielectric constant of FC for a high-frequency/ultra high-frequency wave range, dielectric loss and surface resistivity, to standardize the principle of their measuring methods, measuring tools, adjusting method of samples, procedures of measurement, etc., and to aim at the international standardization. This year, investigation and examination were carried out on various measuring methods including overseas examinations in the U.S., extracting the Fabry-Perot resonator method and a conductive cylindrical dielectric cavity resonator perturbation method for example, and evaluating the specifications of standard reference materials. In addition, a morphological technique was established for measuring sample surfaces affecting measurements, by means of an accurate measuring instrument for thin film surfaces. (NEDO)

259

ACCURATE QUANTIFICATION OF DRIED RESIDUE THIN FILMS USING X-RAY FLUORESCENCE  

An XRF specimen preparation method was developed to quantify the concentration of gallium in plutonium metal while minimizing the risk of contaminating the instrument with radioactive material. To ensure that homogeneous specimens are examined, plutonium is dissolved in dilute HCl and HNO{sub 3} prior to analysis. In the preliminary work here, non-radioactive aqueous gallium standards were prepared, and zinc was added as an internal standard to improve the accuracy and precision. Aliquots from these solutions were cast on Mylar XRF films and air dried prior to analysis. Two methods of casting the solutions were evaluated: (1) casting as a thin layer using a surfactant to wet the support film and (2) casting multiple small spots on the support film. Aqueous gallium standards were prepared and cast as dried residue specimens using each method. These specimens were then analyzed, and calibration curves were prepared. Highly linear calibrations were obtained for each preparation method when zinc was used as the internal standard (RMS values {le}1% of the standards concentration range in both cases). Based on this preliminary work, this dried residue process appears very promising for the accurate quantification of gallium in plutonium.

260

1998 Annual Study Report. Standards development of chemical analysis and non destructive inspection methods for pure titanium metals; 1998 nendo seika hokokusho. Jun chitan no shiken hyoka hoho no hyojunka  

This study was conducted to standardize the chemical analysis and non-destructive inspection methods for pure titanium metals of industrial grade. These methods are among those serving bases for international standardization of products. The chemical analysis is aimed at quantitative analysis of trace impurities, in particular, present in pure titanium metals of industrial grade by developing and standardizing the inductively coupled plasma atomic emission spectroscopy, known for its low detectable limit, and, at the same time, spark and glow discharged atomic emission spectrometry as the improved routine analysis methods. These methods, although being used by, e.g., steel makers, have not been standardized because the effects of titanium-peculiar matrix are not elucidated. The non-destructive testing is aimed at standardization of the techniques useful for automatic production lines. More concretely, these include optical methods aided by a laser or CCD camera for plate surface defect inspection, ultrasonic methods for plate internal defect inspection, and pressure differential methods for air-tightness of welded pipes. They have not been used yet for automatic production lines. (NEDO)

 
 
 
 
261

Management Strategies for Phycotoxin Control  

Sponsors: International Union of Pure and Applied Chemistry and European Commission Standards, Measurements and Testing Programme in collaboration with Food and Agriculture Organisation of the United Nations

262

What is New in Internal Dosimetry and Monitoring?  

This file is divided in two parts:the first one concerns the progress in internal dosimetry. This part gives an overview on new model developments by ICRP, the series of age dependent doses for members of the public was continued by biokinetic and dosimetric models for the embryo and foetus due to activity intake by the mother (ICRP,2001) and for the infant via consumption of mother's milk after activity intake by the mother (ICRP, 2004). In both publications dose coefficients for the embryo and foetus as well the infant were given for various intake scenarios by mother. The present model development work of ICRP is a revision of Publications 30, 54, 68, and 78 based on the new human Alimentary tract model (H.A.T.M.) of ICRP (ICRP, 2006), a revision of absorption parameters for the human respiratory tract model (ICRP, 1994a), new systemic models as well as new dosimetric parameters derived with new Voxel models for the reference male and female adult. The second part concerns the progress in workers monitoring for radionuclide intake. The initiatives to improve the situation are the guidelines published by the International Atomic Energy Agency (2004), giving guidance for the assessment of occupational exposures due to intakes of radionuclides, research project funded by the European Commission: the objective of O.M.I.N.E.X. was the improvement of monitoring programmes, taking into account the uncertainties of biokinetic models and data, the programme I.D.E.A. tried to improve measuring techniques and I.D.E.A.S derives rules for the evaluation of measured activity values in terms of exposure. Standardization projects by the International Standardization Organization I.S.O.: I.S.O. (2001) published a standard defining the requirements for bioassay laboratories, which will soon followed by a second part giving the rationale behind these rules., presently the final version (I.S.O. 2005) of a standard is circulating among the I.S.O. member states which guidance on the design of monitoring programmes, and the draft of another standard will be presented this summer, standardizing the methods to assess exposures on the basis of measured activities (in vivo or in vitro). The I.S.O. standards presently under development try to integrate all these developments and efforts as far as their results were available. Therefore, the following discussion of various aspects of monitoring is based on the I.S.O. 2005 standard. (N.C.)

263

The assay of uranium and plutonium in reprocessing input solutions by isotope dilution mass spectrometry: Results of the isotope dilution analysis measurement evaluation programs  

For analytical methods to be applied to international safeguards, precision and accuracy must be well established. With this objective an interlaboratory measurement evaluation program - ''IDA-80,'' which determined the elemental and isotopic content of the input solutions to reprocessing plants - was carried out with the participation of 33 laboratories from 15 countries or international organizations. It was guided jointly by the Central Bureau for Nuclear Measurements (CBNM) and the Kernforschungszentrum Karlsruhe (KfK) under the auspices of the European Safeguards Reseach and Development Association and with the support of the International Atomic Energy Agency. The element concentrations and isotopic compositions of all test materials were characterized by CBNM and the U.S. National Bureau of Standards to a high accuracy.

264

ENergy and Power Evaluation Program  

In the late 1970s, national and international attention began to focus on energy issues. Efforts were initiated to design and test analytical tools that could be used to assist energy planners in evaluating energy systems, particularly in developing countries. In 1984, the United States Department of Energy (DOE) commissioned Argonne National Laboratory`s Decision and Information Sciences Division (DIS) to incorporate a set of analytical tools into a personal computer-based package for distribution in developing countries. The package developed by DIS staff, the ENergy and Power Evaluation Program (ENPEP), covers the range of issues that energy planners must face: economic development, energy demand projections, supply-and-demand balancing, energy system expansion, and environmental impact analysis. Following the original DOE-supported development effort, the International Atomic Energy Agency (IAEA), with the assistance from the US Department of State (DOS) and the US Department of Energy (DOE), provided ENPEP training, distribution, and technical support to many countries. ENPEP is now in use in over 60 countries and is an international standard for energy planning tools. More than 500 energy experts have been trained in the use of the entire ENPEP package or some of its modules during the international training courses organized by the IAEA in collaboration with Argonne`s Decision and Information Sciences (DIS) Division and the Division of Educational Programs (DEP). This report contains the ENPEP program which can be download from the internet. Described in this report is the description of ENPEP Program, news, forums, online support and contacts.

265

ILRS | Network | Stations | Active Stations | CHAL Site Log  

ILRS Logo, International Laser Ranging Service .... Information : (multiple lines) 5.02 Laser Type : ND:Vanadate, Diode Pumped ... Time and Frequency Standards 9.01.01 Frequency Standard Type : Oven Controlled Crystal Oscillator Model ...

266

Automatic steam traps: definition of technical terms (CTI norm)  

This CTI (Italian Thermotechnical Committee) norm establishes, based on the ISO (International Standard Organization) Norm no. 6552, standardized terminology to be used in the design and fabrication of automatic steam traps.

267

76 FR 22369 - Certain Steel Nails From the People's Republic of China: Initiation and Preliminary Results of...  

...International Trade Administration [A-570-909] Certain Steel Nails From the People's...specifically enumerated and identified in ASTM Standard F 1667 (2005 revision) as Type...specifically enumerated and identified in ASTM Standard F 1667 (2005 revision) as...

268

77 FR 60629 - Administrative Simplification: Adoption of a Standard for a Unique Health Plan Identifier...  

...0938-AQ13 Administrative Simplification: Adoption of a Standard for a Unique Health Plan...titled ``Administrative Simplification: Adoption of a Standard for a Unique Health Plan...page 54674, in our discussion of the adoption of the International Organization...

269

The International Reference Preparations of Clostridium welchii (C. perfringens) Beta and Epsilon Toxoids*  

The Central Veterinary Laboratory, Weybridge, England was requested by the WHO Expert Committee on Biological Standardization to obtain suitable materials for international standards for Clostridium welchii (C. perfringens) beta and epsilon toxoids and to arrange collaborative assays. Preparations w...

270

Safety and quality management  

The present paper deals with international quality standardization and safety connected to offshore installations and ships by ISM certification. Quality assurance by standardization from the series ISO 9000 is discussed in this connection

271

FDA's Standards for High Quality Foods  

... low-calorie products. But despite these adjustments to new consumer demands and conditions, some of the food standards became increasingly incompatible with advanced food-making technology, as well as international food standards. These new ...

272

49 CFR 192.125 - Design of copper pipe.  

...SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE...that does not have an internal corrosion resistant lining may not...9/m3 ) under standard conditions. Standard conditions refers to 60 °F and...

273

Open source systems security certification  

Open Source Systems Security Certification provides an introduction to the notion of the Security Certification, including test-based and model-based approaches to the certification of software products. Several Security Certification standards are presented, including the international standard for...

274

ASTM reference radiologic digital image standards  

ASTM Reference Radiographs have been essential in defining industry`s material defect grade levels for many years. ASTM Reference Radiographs are used extensively as even the American Society for Metals Nondestructive Inspection and Quality Control Metals Handbook, Volume 11, eighth edition refers to ASTM Standard Reference Radiographs. The recently published E 1648 Standard Reference Radiographs for Examination of Aluminum Fusion Welds is a prime example of the on-going need for these references. To date, 14 Standard Reference Radiographs have been published to characterize material defects. Standard Reference Radiographs do not adequately address film-less radiologic methods. There are differences in mediums to content with. On a computer CRT defect indications appear differently when compared to indications viewed in a radiograph on a view box. Industry that uses non-film radiologic methods of inspection can be burdened with additional time and money developing internal standard reference radiologic images. These references may be deemed necessary for grading levels of product defects. Because there are no ASTM Standard Reference Radiologic data files for addressing this need in the industry, the authors of this paper suggested implementing a method for their creation under ASTM supervision. ASTM can assure continuity to those users making the transition from analog radiographic images to digital image data by swiftly addressing the requirements for reference digital image standards. The current status and possible future activities regarding a method to create digital data files is presented in this paper summary.

275

Factor VIII Bypassing Activity (FEIBA) assays: standardization and development of the 1st NIBSC Working Standard for FEIBA - results from a collaborative study.  

Factor-Eight-Inhibitor-Bypassing-Activity (FEIBA) is a bypassing-agent used to control spontaneous bleeding or cover surgical interventions in Haemophiliacs who develop neutralizing antibodies against FVIII/FIX. The market lot-release of FEIBA is dependent on specific clot-based assays, carried out by both the manufacturer and regulatory authorities, relative to manufacturer's in-house standards, which are produced on a small-scale and are replaced frequently. We sought to standardize the FEIBA assay by developing a FEIBA primary standard which would be internationally available in sufficiently large quantities, with a predicted lifetime of many years. A collaborative study involving the manufacturer and three regulatory authorities, was carried out in which a candidate material, sample B (06/172), was calibrated by assays relative to the manufacturer's in-house FEIBA standards (C and D). All laboratories used their routine validated methods (16 APTT-assays, 8 ACTIN-FS-assays and 27 DAPTTIN-assays). Intra-laboratory geometric coefficients of variation (GCVs) for candidate B ranged from 3% to 29% (GCVs participants agreed that candidate B (06/172) be established as the 1st NIBSC Working Standard for FEIBA with an assigned potency of 28.0 units per ampoule, based on combined results for both methods, relative to either standard C or D. PMID:23174010

276

Utility communications architecture  

Integrating communications helps utilities realize the full potential of communications facilities for providing deversified new business opportunities, increasing operational efficiency, improving productivity, and enhancing customer service. This volume, the forth of six volumes, serves as the standard reference for the development and acquisition of communications systems and services that are intended to be compliant with EPRI's Utility Communications Architecture (UCA). The project team identified electric utility information requirements and conducted a series of interviews with 14 diverse US utilities. The work was reviewed and modified based on an EPRI workshop. Two host utilities, Houston Lighting Power Company and Pacific Gas Electric Company, confirmed information requirements and provided associated communications requirements. Teams of industry experts in each of six defined utility functional areas reviewed the communications requirements and broadened them to reflect an industrywide perspective. In subsequent project phases, the team assessed open communication standards in light of the communications requirements and selected standards for inclusion in this specification. They also incorporated feedback from briefings and several workshops. This specification provides a standard reference for the development and acquisition of UCA-compliant communication systems, equipment, and services. It specifies international communications standards that meet the industry's communications requirements. It assumes a high degree of familiarity with standards documentation.

277

Fifty years of atomic time-keeping at VNIIFTRI  

Time metrology in Russia in the second half of the twentieth century has been marked, as in other advanced countries, by the rapid development of time and frequency quantum standards and the beginning of atomic time-keeping. This brief review presents the main developments and studies in time and frequency measurement, and the improvement of accuracy and atomic time-keeping at the VNIIFTRI-the National Metrology Institute keeping primary time and frequency standards and ensuring unification of measurement. The milestones along the way have been the ammonia and hydrogen masers, primary caesium beam and fountain standards and laser frequency standards. For many years, VNIIFTRI was the only world laboratory that applied hydrogen-maser clock ensembles for time-keeping. VNIIFTRI's work on international laser standard frequency comparisons and absolute frequency measurements contributed greatly to the adoption by the CIPM of a highly accurate value for the He-Ne/CH{sub 4} laser frequency. VNIIFTRI and the VNIIM were the first to establish a united time, frequency and length standard. (authors)

278

International Agreement on Planetary Protection  

The maintenance of a NASA policy, is consistent with international agreements. The planetary protection policy management in OSS, with Field Center support. The advice from internal and external advisory groups (NRC, NAC/Planetary Protection Task Force). The technology research and standards development in bioload characterization. The technology research and development in bioload reduction/sterilization. This presentation focuses on: forward contamination - research on the potential for Earth life to exist on other bodies, improved strategies for planetary navigation and collision avoidance, and improved procedures for sterile spacecraft assembly, cleaning and/or sterilization; and backward contamination - development of sample transfer and container sealing technologies for Earth return, improvement in sample return landing target assessment and navigation strategy, planning for sample hazard determination requirements and procedures, safety certification, (liaison to NEO Program Office for compositional data on small bodies), facility planning for sample recovery system, quarantine, and long-term curation of 4 returned samples.

279

How to develop and implement an effective environmental management system  

Development of an Environmental Management System (EMS), as the next step-up from environmental policies, impact assessments, audits, and life cycle assessments, was discussed. The EMS, was said to combine all the aforementioned tools in one package. Developing the system will involve the examination of the company`s current system of management, and the assessment of objectives, risks, and obligations, culminating in the design of the new system. Use of the ISO (International Standards Organization)- recognized EMS elements, including top management commitment, initial environmental review, legal requirements, internal performance criteria, environmental objectives, human, physical and financial resources, provision for communication and reporting, and for measurement and evaluation, was recommended. Other possible methods for developing an EMS were also reviewed briefly.

280

SNL/VNIIEF Storage Monitoring Collaboration  

Sandia National Laboratories (SNL) and the Russian Federal Nuclear Center-All Russian Research Institute for Experimental Physics (VNIIEF)(also know as Arzamas-16) are collaborating on ways to assure the highest standards on safety, security, and international accountability of fissile material. This includes systems used to reduce the need for human access to fissile material, reduce radiation exposure, and provide prompt safety-related information, and provide continuous international accountability information while reducing the need for intrusive, on-site visits. This paper will report on the ongoing SNL/VNIIEF efforts to develop technologies and monitoring systems to meet these goals. Specific topics covered will include: the Smart Bolt tag/seal development, development and testing of electronic sensor platforms (U.S. T-1 ESP and VNIIEF Radio Tag) for monitoring and transportation applications, the ''Magazine-to-Magazine'' remote monitoring system field test, and the ''Facility-to-Facility'' storage monitoring system field trial.

 
 
 
 
281

Progress in developing research-reactor technology for Canadian and international applications  

Atomic Energy of Canada Limited (AECL) continues to develop multipurpose research-reactor technology to meet Canadian and international requirements into the next millennium. Considerable progress has been made in refining the concept for a new Canadian Irradiation Research Facility (JRF) that will underpin the evolutionary development of CANDU (CANada Deuterium Uranium) technology and generate neutrons for basic and applied materials science. Additionally, an IRF-based standardized MAPLE research centre is being developed with various reactor-core options to meet international needs for neutron-beam research plus ancillary isotope production (a 1 5-MW{sub t} 19-site core), for multipurpose materials testing plus neutron-beam applications (a 30-MW{sub t} 31-site core), and high-flux neutron-beam plus materials-testing applications (a 30 to 40-MW{sub t} complex core with twin 18-site core segments). (author)

282

New concepts for bone fracture treatment and the Locking Compression Plate.  

The operative treatment of bone fractures using plates and screws is a standard successful technique. Internal fixation with plates and screws leads to additional trauma and disturbance of the bone blood supply, which increases the risk of delayed union and infection. However, problems also are encountered in the fixation of osteoporotic bone. The locked internal fixator technique is an approach to optimize internal fixation. It aims at flexible elastic fixation to imitate spontaneous healing, including induction of callus formation. The technology supports what is currently called "minimally invasive plate osteosynthesis" (MIPO), which provides priority to biology over mechanics. An implant system called "Locking Compression Plate (LCP)" was developed, based on many years of experience with compression plating and good clinical results obtained with internal fixators, such as the Less Invasive Stabilization Systems (LISS). It combines the two treatment methods (ie, the compression plating and locked internal fixation methods) into one system. This chapter describes the basic principles of locked internal fixators and some clinical results with the LISS and LCP systems to illustrate the potential of these new systems. PMID:15455337

283

The Arms Trade and States' Duty to Ensure Respect for Humanitarian and Human Rights Law  

The unregulated international trade in conventional arms, especially in small arms and light weapons, has come to be viewed as an exacerbating factor in armed conflict, violent crime and internal repression. Concern about the negative humanitarian, development and security impact of this trade has been growing over the last decade. Against this backdrop, the UN General Assembly invited states in December 2006 to consider the feasibility of an instrument establishing common international standards for conventional arms transfers-also known as the ‘Arms Trade Treaty' (ATT). The legality of arms transfers has traditionally been treated as a question of arms control law, but in the recent debate about legal restrictions on states' liberty to transfer arms, norms of international humanitarian and human rights law have frequently been invoked. This article surveys the existing international legal regulation of state-authorised conventional arms transfers, examines how humanitarian law, and in particular states' duty to ensure respect for humanitarian law, affects the legality of these transfers and shows why human rights law does not make a significant contribution to the legal regulation of the international arms trade today.

284

Developing international safety standards for the geological disposal of radioactive waste  

In the context of the International Atomic Energy Agency's (IAEA) programme to create a corpus of internationally accepted Radioactive Waste Safety Standards (RADWASS), focus is currently being placed on establishing standards for the 'geological disposal of radioactive waste'. This is a challenging task and to help the standards development process there is a need to stimulate discussion of some of the associated scientific and technical issues. A number of position papers developed in recent years by a subgroup of the Waste Safety Standards Committee (WASSC), the subgroup on Principles and Criteria for Radioactive Waste Disposal, address many of the relevant issues. These include a common safety based framework for radioactive waste disposal, appropriate time frames for safety assessment, different possible indicators of long-term safety, the safety implications of reversibility and retrievability, the assessment of possible human intrusion into the repository, the role and limitations of institutional control, establishing reference critical groups and biospheres for long-term assessment, and what is meant by 'compliance' with the standards. These papers will be discussed at a Specialists Meeting to be held at the IAEA in June 2001 as a means of establishing the extent to which they enjoy the general support of experts. In order to broaden that consensus, the conclusions reached at the Specialists Meeting on the issues listed above will be presented and discussed with participants at a number of international meetings. Later this year, a draft safety standard on the geological disposal of radioactive waste which takes account of the consensus positions reached through the various consultations will be submitted for the consideration of Waste Safety Standards Committee (WASSC), the officially approved body within the IAEA for the review and approval of waste safety standards. The Committee is made up of government appointed radioactive waste regulators. Subsequent steps include the provision of formal comments by governments, final approval by WASSC, and by the IAEA's Commission on Safety Standards (CSS) and finally by the IAEA's Board of Governors. (author)

285

Hail, Procrustes! Harmonized accounting standards as a Procrustean bed  

This article finds that the use of a harmonized accounting standard, such as the International Financial Reporting Standards, increases the information available to markets only if institutional differences across countries using the harmonized standard are insignificant. In all other cases, harmonization of reporting standards destroys information rather than increasing it. This article also contributes to methodology, introducing techniques for studying nonpartitional information structures.

286

Evaluation of Fourth International Standard for Whole Cell Pertussis Vaccine  

Whole cell pertussis vaccine is still widely used in many countries. An International Standard is needed for its potency control. The Third International Standard for Pertussis Vaccine was prepared about 40 years ago and its replacement was recommended by the Expert Committee for Biological Standardisation (ECBS) of the WHO. Material in ampoules coded 94/532 was prepared as a candidate replacement and has been evaluated in international collaborative studies which consisted of two parts. The first part, to assess the suitability of the candidate standard by comparing it with the Second International Standard for Pertussis Vaccine (IS2) involved 14 laboratories in 11 countries. The second part to compare the candidate standard with the Third International Standard for Pertussis Vaccine (IS3...

287

International nuclear fuel cycle fact book. Revision 4  

This Fact Book has been compiled in an effort to provide (1) an overview of worldwide nuclear power and fuel cycle programs and (2) current data concerning fuel cycle and waste management facilities, R and D programs, and key personnel in countries other than the United States. Additional information on each country's program is available in the International Source Book: Nuclear Fuel Cycle Research and Development, PNL-2478, Rev. 2. The Fact Book is organized as follows: (1) Overview section - summary tables which indicate national involvement in nuclear reactor, fuel cycle, and waste management development activities; (2) national summaries - a section for each country which summarizes nuclear policy, describes organizational relationships and provides addresses, names of key personnel, and facilities information; (3) international agencies - a section for each of the international agencies which has significant fuel cycle involvement; (4) energy supply and demand - summary tables, including nuclear power projections; (5) fuel cycle - summary tables; and (6) travel aids - international dialing instructions, international standard time chart, passport and visa requirements, and currency exchange rate.

288

International Nuclear Fuel Cycle Fact Book. Revision 5  

This Fact Book has been compiled in an effort to provide: (1) an overview of worldwide nuclear power and fuel cycle programs; and (2) current data concerning fuel cycle and waste management facilities, R and D programs, and key personnel in countries other than the United States. Additional information on each country's program is available in the International Source Book: Nuclear Fuel Cycle Research and Development, PNL-2478, Rev. 2. The Fact Book is organized as follows: (1) Overview section - summary tables which indicate national involvement in nuclear reactor, fuel cycle, and waste management development activities; (2) national summaries - a section for each country which summarizes nuclear policy, describes organizational relationships and provides addresses, names of key personnel, and facilities information; (3) international agencies - a section for each of the international agencies which has significant fuel cycle involvement; (4) energy supply and demand - summary tables, including nuclear power projections; (5) fuel cycle - summary tables; and (6) travel aids international dialing instructions, international standard time chart, passport and visa requirements, and currency exchange rate.

289

Assuring fish safety and quality in international fish trade  

International trade in fishery commodities reached US$ 58.2 billion in 2002, a 5% improvement relative to 2000 and a 45% increase over 1992 levels. Within this global trade, developing countries registered a net trade surplus of US$ 17.4 billion in 2002 and accounted for almost 50% by value and 55% of fish exports by volume. This globalization of fish trade, coupled with technological developments in food production, handling, processing and distribution, and the increasing awareness and demand of consumers for safe and high quality food have put food safety and quality assurance high in public awareness and a priority for many governments. Consequently, many countries have tightened food safety controls, imposing additional costs and requirements on imports. As early as 1980, there was an international drive towards adopting preventative HACCP-based safety and quality systems. More recently, there has been a growing awareness of the importance of an integrated, multidisciplinary approach to food safety and quality throughout the entire food chain. Implementation of this approach requires an enabling policy and regulatory environment at national and international levels with clearly defined rules and standards, establishment of appropriate food control systems and programmes at national and local levels, and provision of appropriate training and capacity building. This paper discusses the international framework for fish safety and quality, with particular emphasis on the United Nation's Food and Agricultural Organization's (FAO) strategy to promote international harmonization and capacity building.

290

Recent Development and Utilization of Two-Way Satellite Time and Frequency Transfer  

TWSTFT (Two Way Satellite Time and Frequency Transfer) has been developed for a long time, and has become one of the most precise and accurate techniques for comparison of the frequency standards located at remote sites. Since 1999, TWSTFT has been used in TAI (International Atomic Time) generation. More than two-thirds of TAI clocks and almost all the primary frequency standards are transferred using TWSTFT. To increase the time transfer precision and stability, several calibration methods were developed and the possible instability sources were investigated. Due to the high redundancy of the time transfer links and quick developments of independent time transfer techniques (e.g. GPS), much utilization was proposed to enhance the robustness, to reduce the uncertainty, and to reduce the di...

291

Compliance of Bhabhatron-II telecobalt unit with IEC standard - Radiation safety.  

Bhabha Atomic Research Centre, Mumbai, India designed and developed a telecobalt unit, which was named as Bhabhatron-II. In this paper, the results pertaining to radiation safety of indigenously developed Bhabhatron-II telecobalt unit are reported. The various tests were carried out as per requirements of International Electrotechnical Commission standard and acceptance criteria developed nationally. Various devices such as CaSO4:Dy based thermoluminescent dosimeters, farmer type ionization chamber, water phantom and radiographic films were used. All the parameters pertaining to radiation leakage/transmission were within the tolerance limits as per IEC-60601-2-11 standard except the collimator transmission through X collimators (upper jaw), which marginally exceeds the tolerance limit. PMID:19458599

292

UK and international standards for nuclear health and safety  

This abstract summarises the licensing regime applied to nuclear installations in the UK, and explains the historical development of the NII's health and safety standards for such installations. The impact of two major public inquiries (Sizewell ''B'' and Hinkley Point ''C'') is discussed in terms of the development of NII's 'Safety Assessment Principles' and HSE's 'Tolerability of Risk from Nuclear Power Stations'. The role of international organisations (IAEA, ICRP, OECD/NEA and the EC) in developing nuclear and radiation safety standards is discussed. The paper concludes with some thoughts about how closer harmonisation might be achieved in the future. (author).

293

Interoperability of Standards for Robotics in CIME : Research Reports Esprit-Project 6457-InterRob-Vol.1  

Esprit Project 6457 "Interoperability of Standards for Robotics in CIME (InterRob)" belongs to the Subprogramme "Integration in Manufacturing" of Esprit, the European Specific Programme for Research and Development in Information Technology supported by the European Commision.The first main goal of InterRob was to close the information chain between product design, simulation, programming, and robot control by developing standardized interfaces and their software implementation for standards STEP (International Standard for the Exchange of Product model data, ISO 10303) and IRL (Industrial Robot Language, DIN 66312). This is a continuation of the previous Esprit projects CAD*I and NIRO, which developed substantial basics of STEP.The InterRob approach is based on standardized models for product geometry, kinematics, robotics, dynamics and control, hence on a coherent neutral information model of the process chain from design to manufacturing.The second main goal of the project was to increase the accuracy of off-line programmed robots by improving the conformance of robot simulation with the real world, and by on-line adjustments in robot control to modify actual positions and speed of the robot tool. In industrial applications it was demonstrated that complete off-line programming will significantly shorten production preparation and will increase product quality as well as productivity and return on investment for expensive installations.

294

A review on test procedure, energy efficiency standards and energy labels for room air conditioners and refrigerator-freezers  

Air conditioners and refrigerator-freezers are major energy users in a household environment and hence efficiency improvement of these appliances can be considered as an important step to reduce their energy consumption along with environmental pollution prevention. Energy efficiency standards and labels are commonly used tools to reduce the energy uses for household appliances for many countries around the world. The first step towards adopting energy efficiency standards is to establish a test procedure for rating and testing of an appliance. It may be mentioned that an energy test procedure is the technical foundation for energy efficiency standards, energy labels, and other related programs. This paper reviews requirements and specifications of various international test standards for testing and rating of room air conditioners and refrigerators. A review on the development of the energy efficiency standards has been provided as well. Finally, energy labels that provide some useful information for identifying energy efficient products have been reviewed for these appliances. It may be stated that the review will be useful for the developing countries who wish to develop these energy savings strategies. It is also expected to be useful to revise the existing strategies for a few selected countries who already implemented these strategies earlier. (author)

295

Final Technical Report: Hydrogen Codes and Standards Outreach  

This project contributed significantly to the development of new codes and standards, both domestically and internationally. The NHA collaborated with codes and standards development organizations to identify technical areas of expertise that would be required to produce the codes and standards that industry and DOE felt were required to facilitate commercialization of hydrogen and fuel cell technologies and infrastructure. NHA staff participated directly in technical committees and working groups where issues could be discussed with the appropriate industry groups. In other cases, the NHA recommended specific industry experts to serve on technical committees and working groups where the need for this specific industry expertise would be on-going, and where this approach was likely to contribute to timely completion of the effort. The project also facilitated dialog between codes and standards development organizations, hydrogen and fuel cell experts, the government and national labs, researchers, code officials, industry associations, as well as the public regarding the timeframes for needed codes and standards, industry consensus on technical issues, procedures for implementing changes, and general principles of hydrogen safety. The project facilitated hands-on learning, as participants in several NHA workshops and technical meetings were able to experience hydrogen vehicles, witness hydrogen refueling demonstrations, see metal hydride storage cartridges in operation, and view other hydrogen energy products.

296

Problems associated with clinical trials of Ayurvedic medicines/ Problemas associados com ensaios clínicos de medicamentos Ayurvédicos  

Abstract in english Herbal drugs have been used since ancient times as medicines for the treatment of various diseases. Especially in countries like India many of herbal drugs and formulations are used in different practices of treatment like Ayurveda, Siddha and Unani. It is estimated that about 25% of all modern medicines are directly or indirectly derived from plants sources. The contribution of developing countries in global herbal business is very poor due to lack of quality control and (more) standardization measures. There is lack of common standards and appropriate methods for evaluating Traditional Medicine to ensure the safety, efficacy and quality control. This indicates the importance and necessity to develop a standard operational procedure for the standardization of herbal drugs and formulations. Benchmarking the evaluation protocols including both quality control and quality assurance of herbal drugs would play a major role in providing highly reliable and effective herbals drugs and to attract international trade, thus generating revenue. The article highlights various problems being faced by developing countries and suggests a unique approach for the preparation of SOP/guidelines for the standardization of all herbal based formulations, also there is a need for systematic clinical trials of traditional plant based medicines to enhance global acceptance

297

Solving the Problem: Genome Annotation Standards before the Data Deluge  

The promise of genome sequencing was that the vast undiscovered country would be mapped out by comparison of the multitude of sequences available and would aid researchers in deciphering the role of each gene in every organism. Researchers recognize that there is a need for high quality data. However, different annotation procedures, numerous databases, and a diminishing percentage of experimentally determined gene functions have resulted in a spectrum of annotation quality. NCBI in collaboration with sequencing centers, archival databases, and researchers, has developed the first international annotation standards, a fundamental step in ensuring that high quality complete prokaryotic genomes are available as gold standard references. Highlights include the development of annotation assessment tools, community acceptance of protein naming standards, comparison of annotation resources to provide consistent annotation, and improved tracking of the evidence used to generate a particular annotation. The development of a set of minimal standards, including the requirement for annotated complete prokaryotic genomes to contain a full set of ribosomal RNAs, transfer RNAs, and proteins encoding core conserved functions, is an historic milestone. The use of these standards in existing genomes and future submissions will increase the quality of databases, enabling researchers to make accurate biological discoveries.

298

Classification and Subject Cataloguing Section. Bibliographic Control Division. Papers.  

Papers on classification and subject cataloging which were presented at the 1983 International Federation of Library Associations (IFLA) conference include: (1) "PRECIS: Basic Principles, Function, and Use," in which Derek Austin (United Kingdom) describes the automated subject indexing system developed for use in the "British National Bibliography"; (2) "The PRECIS Project of the Deutsche Bibliothek [at] Frankfurt am Main," in which Bernd Maassen (West Germany) outlines project background and activities as well as criticisms of PRECIS; (3) "Computer-Aided Subject Cataloguing at the Deutsche Bibliothek in Frankfurt am Main," a review by Barbara Kelm (West Germany) of indexing principles, computer-generated indexing aids, central information services of the Deutsche Bibliothek, and possibilities for cooperative subject cataloging; (4) "Waiting for Technology: An Overview of Bibliographic Services in the Third World," in which Dorothy Anderson discusses the introduction of information technology and library development in the Third World; (5) "Problems in the Cataloguing of the Products of Rapidly Changing Technologies: With Special Reference to Machine-Readable Files" by Lenore Coral (United States), which discusses different methods for cataloging machine readable databases; and (6) "International Bibliographic Filing Principles and Rules" by Ernst Kohl (West Germany), which describes standardization of bibliographic filing rules and the development of International Standard ISO 7154. (ESR)

299

Workshop report on the extraction of foetal DNA from maternal plasma  

Objective Cell free foetal DNA (cff DNA) extracted from maternal plasma is now recognized as a potential source for prenatal diagnosis but the methodology is currently not well standardized. To evaluate different manual and automated DNA extraction methods with a view to developing standards, an International Workshop was performed.Methods Three plasma pools from RhD-negative pregnant women, a DNA standard, real-time-PCR protocol, primers and probes for RHD were sent to 12 laboratories and also to one company (Qiagen, Hilden, Germany). In pre-tests, pool 3 showed a low cff DNA concentration, pool 1 showed a higher concentration and pool 2 an intermediate concentration.Results The QIAamp DSP Virus Kit, the High Pure PCR Template Preparation Kit, an in-house protocol using the QIAamp DNA Blo...

300

Database use in developing advanced composites  

One of the barriers in bringing advanced composites to market is the inability to demonstrate adherence to specifications of the material properties of materials designed by standardized procedures with standardized tools. This paper describes the Advanced Materials Professional (AMPro) database approach that provides (1) uniform and standardized records of material property tests, (2) easy transfer of data and metadata from development to industrial use, and (3) the ability to explore relationships between material design parameters and the resulting material properties. The AMPro database uses 19 internal material-related databases to tie together all of the information needed to provide a full pedigree for the thermomechanical data on composite parts and samples. Systematic data entry procedures provide for easy data input that nonetheless prompts for all required metadata. Powerful query procedures then provide detailed search capabilities for materials that meet specific conditions. Query results are directable to reports, graphs, and other software.

 
 
 
 
301

Preparation and evaluation of the 1st international standard for the quantitation of HIV-2 RNA in plasma  

An international standard for the quantitation of HIV-2 RNA in plasma samples was developed. A collaborative study involving 29 laboratories from 15 countries was carried out in order to evaluate HIV-2 RNA candidate materials for use with nucleic acid-based tests (NATs). Candidate reference standards consisted of duplicate copies of two HIV-2 genotype A viruses, HIV-2 CAM2 and HIV-2 ROD and were coded S1-S4. Each laboratory assayed all four candidates on at least three separate occasions and data were collated and analysed at NIBSC. Of the data sets returned the majority were from qualitative assays. All assays detected both candidate standards with the exception of one commercial assay, the Nuclisens Easy Q, which was designed primarily for HIV-1 detection which did not detect HIV-2 CAM2 ...

302

Harmonizing ISO/IEC 15504 and CMMI  

The requirements for conformance of a process model to the international standard for process assessment, ISO/IEC 15504, cover a broad range. The most significant of these is the need to establish a complete and unambiguous mapping between the Process Assessment Model and the relevant Process Reference Model and the Measurement Framework described in the Standard. This is required to support the development of a mechanism for translating the outputs from an assessment using the Process Assessment Model into the standard process profiles defined in ISO/IEC 15504. This article reports the results of an analysis of the relationship between CMMI, as a `candidate conformant Process Assessment Model', relative to the Measurement Framework defined in ISO/IEC 15504-2, and the Process Reference Mod...

303

Analysis of sediment-associated insecticides using ultrasound assisted microwave extraction and gas chromatography-mass spectrometry  

An ultrasound assisted microwave extraction (UAME) method was developed to simultaneously extract five organophosphate (OP) and eight pyrethroid insecticides from sediment. The optimized UAME conditions were to use 100ml of a mixture of hexane and acetone (1:1, v/v) solution as the extraction solvents, and extraction time, microwave and ultrasonic power settings of 6min, 100W and 50W, respectively. Extracts were cleaned using solid phase extraction and analyzed by gas chromatography-mass spectrometry in negative chemical ionization mode and quantification was based on matrix-matched standard solutions along with internal standard calibration. At the spiked concentrations of 1, 5 and 20ng/g dry weight (dw), recoveries of OPs were 77.6-122%, 65.2-128% and 75.6-141% with relative standard dev...

304

Determination of elemental composition of river water and slime by PIXE method  

The application of PIXE method was developed for determination of concentration of different elements in river water and bottom slime. The internal standard technique was applied for quantitative evaluation of contents of different elements. In case of river water yttrium standard was used in form of yttrium nitrate solution. The measurements for bottom slime was performed with external beam using standards with predetermined concentration of different elements. The concentration of following elements: S, Cl, K, Ca, Ti, V, Cr, Mn, Fe, Ni, Cu, Zn, Se, Br, Rb, Sr, Zr, Hg, Pb was determined with the described procedure. The estimated concentration of elements ranged from about 0.05 to about 200 ppm for water samples and from about 1.5 to about 30000 ppm in bottom slime samples.

305

Considerations about ISO 14001, and suggestions for the next revision  

The aim of this paper is to discuss a number of issues related to ISO 14001:2004, the international standard for environmental management systems (EMS) with the purpose of improving the next edition in order to recognize and reflect new recognitions in approaches to pollution prevention. The standard is a process standard that leaves room for interpretation at company level as well as among lead auditors from certifying bodies. A case study is presented and shows lack of life cycle thinking in product development. The paper suggests changes of ISO 14001:2004 in order to include a clear product focus. It is also suggested to formulate clearer demands for targets and environmental improvements, and to include a demand for publication of an environmental report to promote a constructive dialogue with relevant stakeholders.

306

Internal dose assessment in radiation accidents  

Although numerous models have been developed for occupational and medical internal dosimetry, they may not be applicable to an accident situation. Published dose coefficients relate effective dose to intake, but if acute deterministic effects are possible, effective dose is not a useful parameter. Consequently, dose rates to the organs of interest need to be computed from first principles. Standard bioassay methods may be used to assess body contents, but, again, the standard models for bioassay interpretation may not be applicable because of the circumstances of the accident and the prompt initiation of decorporation therapy. Examples of modifications to the standard methodologies include adjustment of biological half-times under therapy, such as in the Goiania accident, and the same effect, complicated by continued input from contaminated wounds, in the Hanford {sup 241}Am accident. (author)

307

Aid and Growth in Small Island Developing States  

Aid flows to small island developing states (SIDS) are enormous by international standards when compared to the size of their economies. Yet these countries face many severe economic challenges and many have experienced declines in the living standards of their citizens. This paper looks at the impact of aid on what is treated as a necessary precondition for improvements in living standards, typically defined. Specifically, it examines the impact of foreign aid on real per capita income growth in SIDS by econometrically analysing cross-country data for the period 1980 to 2004. A variety of econometric techniques and measures of aid are used. Results suggest that foreign aid is effective at spurring economic growth but with diminishing returns.

308

Thermodynamic properties of standard seawater  

(p, ?, T) data of standard seawater with practical salinity S?35 (corresponding to an absolute salinity SA?35.16504 g/kg) measured at T=(273.14 to 468.06) K and pressures up to p=140 MPa are reported with an estimated experimental relative combined standard uncertainty of 0.006% in density. The measurements were made with a newly constructed vibration-tube densimeter. The system was calibrated using double-distilled water, methanol and aqueous NaCl solutions. An empirical correlation for the density of standard seawater has been developed as a function of pressure and temperature. This equation of state was used to calculate other volumetric properties such as isothermal compressibility, isobaric thermal expansibility, differences in isobaric and isochoric heat capacities, thermal pressure coefficient, internal pressure and secant bulk modulus. The results can be used to extend the present equation of state of seawater to higher temperature as a function of pressure.

309

Preparation of stable standards of biological tissues for laser ablation analysis  

A novel method for preparation of durable standards of biological samples for quantitative analysis by laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) has been developed. Rat brain tissue samples were ground and then spiked by aqueous solutions containing controlled amounts of trace metals of interest. The spiked rat brain samples were then encapsulated in a sol-gel matrix produced by tetraethyl orthosilicate (TEOS). The spiked standards were prepared by addition of 0-50mgg^-^1 of eight elements (Li, Co, Cr, Cu, Fe, Mn, Pb and Zn) to the biological samples. The correlation coefficients of the calibration curves for all elements tested were better than 0.97. Carbon-13, found in all biological samples, was used as an internal standard to correct for variations in the ...

310

Eine standardisierte Ubersetzung der STAndards for Reporting of Diagnostic accuracy studies (STARD Statement) in Deutsch: Methodische Aspekte  

Background: In order to be comprehensible and comparable scientific data should be reported according to a certain standard. One example is the 'STAndards for Reporting of Diagnostic Accuracy (STARD) Statement', a 25-item checklist for the appropriate conduct and reporting of diagnostic studies. Usually such scientific standards are published in English. The International Society for Pharmacoeconomics and Outcome Research (ISPOR) has developed guidelines for the translation and cultural adaptation of written medical instruments. The aim was to apply these ISPOR criteria to the German translation of the STARD Statement in order to allow for authorisation to be conferred by the original authors. Methods: In cooperation with the original authors the STARD statement was translated according to...

311

Insecticides extraction from banana leaves using a modified QuEChERS method  

An analytical method employing gas chromatography (GC) with nitrogen-phosphorus detection has been developed for the simultaneous determination of eight insecticides (seven organophosphorus pesticides: ethoprophos, diazinon, chlorpyrifos-methyl, fenitrothion, malathion, chlorpyrifos and fenamiphos, and one thiadiazine: buprofezin) in banana leaves that are currently being used to feed cattle or hogs. The extraction and preconcentration of these pesticides were carried out using a modified QuEChERS procedure and the whole method was validated in terms of repeatability, linearity, precision and accuracy. Triphenylphosphate was used as internal standard. Matrix effect evaluation was also carried out using a matrix matched calibration. The developed procedure gave satisfactory recovery (89-104...

312

Comparison between the acetylene reduction method, the isotope dilution method and the total nitrogen difference method for measuring nitrogen fixation in lucerne (Medicago sativa L. )  

In view of the increasing need for the exact estimation of the input of nitrogen in agroecosystems, an application of the acetylene-reduction technique was developed. The technique, consisting of a plastic bag incubation system, using propane as an internal standard of the apparent volume, made it possible to carry out repeated incubations on the same plant system. The developed in situ acetylene-reduction technique was compared with an isotope dilution method and a total nitrogen difference method. By comparing the derived total nitrogen fixation values from each with the value derived from the acetylene-reduction method; it was shown that the values differed significantly. (Auth.). 15 refs.; 1 figure; 2 tabs.

313

Automated capillary electrophoresis with on-line preconcentration by solid phase extraction using a sequential injection manifold and contactless conductivity detection  

An extension of a capillary electrophoresis instrument coupled to a sequential injection analysis manifold was developed for automated measurements with on-line solid-phase extraction preconcentration. An in-house built capacitively coupled contactless conductivity detector was employed for sensitive detection with narrow capillaries of 25mm internal diameter. The system was assembled into standardized 19in. frames and racks for easy transport and mobile deployment. The system can be left running unattendedly without manual intervention with good operation stability. To demonstrate the application of the system, a method for the determination of four drugs, namely ibuprofen, diclofenac, naproxen and bezafibrate, was developed with enrichment factors of up to several hundreds. Detection of ...

314

Development of NASA's Space Communications and Navigation Test Bed Aboard ISS to Investigate SDR, On-Board Networking and Navigation Technologies  

NASA is developing an experimental flight payload (referred to as the Space Communication and Navigation (SCAN) Test Bed) to investigate software defined radio (SDR), networking, and navigation technologies, operationally in the space environment. The payload consists of three software defined radios each compliant to NASA s Space Telecommunications Radio System Architecture, a common software interface description standard for software defined radios. The software defined radios are new technology developments underway by NASA and industry partners. Planned for launch in early 2012, the payload will be externally mounted to the International Space Station truss and conduct experiments representative of future mission capability.

315

Forty-five minutes of physical activity at school each day? Curricular promotion of physical activity in grades one to four  

Aim According to the US Department of Health and Human Services (2008) and the World Health Organization (2008), regular physical activity is essential to the healthy development of children and contributes to the reduction of chronic diseases throughout their life span. However, coordinated comprehensive national and international programs to promote physical activity and sports participation are lacking. According to the German Sports Federation (2006), physical education (PE) classes at German schools are increasingly being canceled or taught outside the school. "fit for pisa" is a German intervention developed in response to the demand for scientific evaluation of interventions like daily physical education. Its goal is to provide quality management-secured, structured and standardized...

316

Development of the Intercontrol Center Communications Protocol (ICCP)  

After a three-year research and development project that included a collaborative effort by EPRI and 20 utilities and vendors, two electric utilities conducted full-scale demonstrations of a proposed international standard, UCA{trademark} compliant protocol for communicating between control centers. The recently developed Intercontrol Center Communications Protocol (ICCP) was implemented and tested at Western Area Power Administration`s (WAPA) Loveland Area Office and at Ohio Edison (OE) Company. A third node at the vendor, Harris Controls, allowed demonstration of routing and networking capabilities.

317

Structured Extended Finite Element Methods of Solids Defined by Implicit Surfaces  

A paradigm is developed for generating structured finite element models from solid models by means of implicit surface definitions. The implicit surfaces are defined by radial basis functions. Internal features, such as material interfaces, sliding interfaces and cracks are treated by enrichment techniques developed in the extended finite element method (X-FEM). Methods for integrating the weak form for such models are proposed. These methods simplify the generation of finite element models. Results presented for several examples show that the accuracy of this method is comparable to standard unstructured finite element methods.

318

Standardisation of the USGS Volcano Alert Level System (VALS): analysis and ramifications  

The standardisation of volcano early warning systems (VEWS) and volcano alert level systems (VALS) is becoming increasingly common at both the national and international level, most notably following UN endorsement of the development of globally comprehensive early warning systems. Yet, the impact on its effectiveness, of standardising an early warning system (EWS), in particular for volcanic hazards, remains largely unknown and little studied. This paper examines this and related issues through evaluation of the emergence and implementation, in 2006, of a standardised United States Geological Survey (USGS) VALS. Under this upper-management directive, all locally developed alert level systems or practices at individual volcano observatories were replaced with a common standard. Research co...

319

Recent Progress in Research on and Code Evaluation of Concrete Creep and Shrinkage in Japan  

This paper introduces the recent state of research on creep and shrinkage of concrete in Japan, focusing on several unique advances: new prediction models in design code, development of database, autogenous shrinkage and prediction of cracks in structural members. New prediction models for creep and shrinkage of concrete, which can be applied to high-strength concrete, were adopted in the JSCE standard specification for concrete structures in 2002. A creep and shrinkage database was developed and made available for international use. Thus Japanese researchers can be said to have made important contributions to research on autogenous shrinkage of concrete in the last ten years.   

320

Prevention and treatment of bile duct injuries during laparoscopic cholecystectomy: the clinical practice guidelines of the European Association for Endoscopic Surgery (EAES)  

Background Laparoscopic cholecystectomy is one of the most common surgical procedures in Europe (and the world) and has become the standard procedure for the management of symptomatic cholelithiasis or acute cholecystitis in patients without specific contraindications. Bile duct injuries (BDI) are rare but serious complications that can occur during a laparoscopic cholecystectomy. Prevention and management of BDI has given rise to a host of publications but very few recommendations, especially in Europe. Methods A systematic research of the literature was performed. An international expert panel was invited to appraise the current literature and to develop evidence-based recommendations. Statements and recommendations were drafted after a consensus development conference in May 2011, follo...

 
 
 
 
321

Robust approachability and regret minimization in games with partial monitoring  

Approachability has become a standard tool in analyzing learning algorithms in the adversarial online learning setup. We develop a variant of approachability for games where there is ambiguity in the obtained reward that belongs to a set, rather than being a single vector. Using this variant we tackle the problem of approachability in games with partial monitoring and develop simple and efficient algorithms (i.e., with constant per-step complexity) for this setup. We finally consider external and internal regret in repeated games with partial monitoring, for which we derive regret-minimizing strategies based on approachability theory.

322

â?????Putting onâ???? Sexiness: A Content Analysis of the Presence of Sexualizing Characteristics in Girlsâ?????? Clothing  

Objectification theory (Fredrickson and Roberts 1997) proposes that women from Western cultures are widely portrayed and treated as objects of the male gaze, leading to the development of self-objectification, in which girls and women internalize these societal messages and view their own bodies as objects to be evaluated according to narrow standards of (often sexualized) attractiveness. Prompted by findings from the American Psychological Association Task Force on the Sexualization of Girls (APA 2007), the present study considers girlsâ?????? clothing as a possible socializing influence that may contribute to the development of self-objectification in preteen girls. Accordingly, in this content analysis, we examined the frequency and nature of â?????sexualizingâ???? clothing availab...

323

Global standard for the composition of infant formula: recommendations of an ESPGHAN coordinated international expert group.  

The Codex Alimentarius Commission of the Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO) develops food standards, guidelines and related texts for protecting consumer health and ensuring fair trade practices globally. The major part of the world's population lives in more than 160 countries that are members of the Codex Alimentarius. The Codex Standard on Infant Formula was adopted in 1981 based on scientific knowledge available in the 1970s and is currently being revised. As part of this process, the Codex Committee on Nutrition and Foods for Special Dietary Uses asked the ESPGHAN Committee on Nutrition to initiate a consultation process with the international scientific community to provide a proposal on nutrient levels in infant formulae, based on scientific analysis and taking into account existing scientific reports on the subject. ESPGHAN accepted the request and, in collaboration with its sister societies in the Federation of International Societies on Pediatric Gastroenterology, Hepatology and Nutrition, invited highly qualified experts in the area of infant nutrition to form an International Expert Group (IEG) to review the issues raised. The group arrived at recommendations on the compositional requirements for a global infant formula standard which are reported here. PMID:16254515

324

Assay of zofenopril and its active metabolite zofenoprilat by liquid chromatography coupled with tandem mass spectrometry.  

Zofenopril is a pro-drug designed to undergo metabolic hydrolysis yielding the active free sulfhydryl compound zofenoprilat, which is an angiotensin converting enzyme (ACE) inhibitor, endowed also with a marked cardioprotective activity. A simple, highly sensitive specific LC-MS-MS method was developed for the determination of zofenopril and zofenoprilat in human plasma. In order to prevent oxidative degradation of zofenoprilat and its internal standard, their free sulfhydryl groups were protected by treatment with N-ethylmaleimide (NEM), which produced the succinimide derivatives. The compounds and their corresponding fluorine derivatives, used as internal standards, were extracted from plasma with toluene. The reconstituted dried extracts were chromatographed and then monitored by a triple-stage-quadrupole instrument operating in the negative ion spray ionization mode. The method was validated over the concentration range of 1-300 ng/ml for zofenopril and 2-600 ng/ml for zofenoprilat. Inter- and intra-assay precision and accuracy of both zofenopril and zofenoprilat were better than 10%. The limit of quantitation was 1 ng/ml with zofenopril and 2 ng/ml with zofenoprilat. Extraction recovery proved to be on average 84.8% with zofenopril and 70.1% with zofenoprilat. Similar recoveries were shown by the above two internal standards. The method was applied to measure plasma concentrations of zofenopril and zofenoprilat in 18 healthy volunteers treated orally with zofenopril calcium salt at the dose of 60 mg. PMID:11145066

325

Liquid Chromatographic Determination of Plasma Ropivacaine for Assessing Pharmacokinetics of the Viscous Preparation  

We developed assay method for determination of plasma ropivacaine by using reversed-phase high performance liquid chromatography (HPLC) equipped with ordinary octadecylsilyl silica-gel (ODS) column. Plasma samples spiked with internal standard (bupivacaine) were treated by ethylacetate to extract ropivacaine and internal standard. The ropivacaine and internal standard separated on ODS column were detected by an ultra violet (UV) detector set at 215 nm. The mobile phase solvent consisted of acetonitrile, methanol and 0.05 M phosphate buffer adjusted to pH 4.0 (10 : 30 : 60, v/v) was pumped at a flow rate of 0.8 ml/min. The calibration curve of ropivacaine was linear at the concentration of 25—1000 ng/ml (r=0.9998). The recoveries of ropivacaine from plasma were greater than 87.9% with the coefficient of variations (CVs) less than 6.1%. The CVs for intra- and inter-day assay of ropivacaine were 2.0—12.0% and 1.7—14.8%, respectively. This HPLC method was applied to determining plasma ropivacaine in two healthy subjects after receiving 0.5% ropivacaine viscous preparation, which was prepared in our hospital. Our preliminary pharmacokinetic data showed that ropivacaine viscous could be used safely based on the plasma ropivacaine concentrations (Cmax: 89—125 ng/ml) for pain relief in oral mucosa.   

326

The First International Standard for Antitetanus Immunoglobulin, Human; pharmaceutical evaluation and international collaborative study.  

The First International Standard (IS) for Antitetanus Immunoglobulin, Human (coded 26/488) was established by the WHO Expert Committee on Biological Standardization in October 1992 on the basis of an extensive pharmaceutical evaluation and an international collaborative study. Fifteen laboratories from 15 countries performed the toxin neutralization assay in vivo in the study. Twelve laboratories also performed an alternative in vitro assay. The new International Standard is a purified human immunoglobulin containing antibodies which are able to neutralize tetanus toxin. This new standard replaces the Second International Standard for Tetanus antitoxin, Equine, for testing of human antitetanus immunoglobulin preparations used clinically as well as for titration of human serum samples for tetanus antitoxin. The new International Standard was assigned a potency of 120 International Units (IU) of Tetanus Antitoxin per ampoule on the basis of its calibration in terms of the International Unit defined by the Second International Standard for Tetanus Antitoxin, Equine by toxin neutralization assay in vivo. The same preparation was also established as the first European Pharmacopoeia Standard for Antitetanus Immunoglobulin, Human by the European Pharmacopoeia Commission, Biological Standardization Programme in March 1993. PMID:8217120

327

Critical Success Factors in the Implementation of International Development Projects in Kazakhstan  

International aids, which target socio-development in developing and/or underdeveloped countries, are generally undertaken through projects. These projects, which are named as international development projects (IDPs), are financed mainly by multilateral and bilateral development agencies. Howeve...

328

Data acquisition systems. Final report  

The program has included continued extension and maintenance of the specifications for data acquisition systems for high energy physics applications. Work continued on the study, development and specification of the FASTBUS system and of other systems to meet the changing needs of the community. The approach has maximized the use of available, technology, systems, subsystems, and components. Work on a version of FASTBUS optimized for accelerator and experiment control applications, and interfaces to other busses has been examined to see to what extent existing systems can be utilized. Processing of the revised editions the ANSI/IEEE standards was be pursued so that they can be published in 1994. This applies also to the corresponding international standards of the International Electrotechnical Commission (IEC) though the international processing is expected to take somewhat longer. The project provides a clearing house for data acquisition system information and maintains liaison with and collaborates with the ESONE Committee of European Laboratories and national and international laboratories involved with data acquisition and control systems for high energy and nuclear physics.

329

EPR Dosimetry - Present and Future  

In the past, IAEA has played a central role in stipulating research and development in EPR high-dose standardisation as well as in coordinating and organising international dose intercomparison programs, within the Member States of the United Nations from the mid-seventies till today. The future tasks of EPR dosimetry seem to tend towards different subjects such as bio markers, biological radiation effects, post-accident dose reconstruction in the environment, and retrospective human dosimetry. The latter may be considered a promising tool for epidemiology on the way to re-define radiation risk of man for chronicle radiation exposures, based on e.g. South Ural civil population and radiation workers. There are on-going international activities in the field of standardising high-level dosimetry by the American Standards on Testing and Materials (Astm), and by the International Organisation of Standards (ISO). The International Commission on Radiation Units and Measurements (ICRU) is considering the establishment of relevant recommendations concerning industrial radiation processing, but also human dose reconstruction. (Author)

330

Stakeholder identification of advanced technology opportunities at international ports of entry  

As part of the Advanced Technologies for International and Intermodal Ports of Entry (ATIPE) Project, a diverse group of stakeholders was engaged to help identify problems experienced at inland international border crossings, particularly those at the US-Mexican border. The fundamental issue at international ports of entry is reducing transit time through the required documentation and inspection processes. Examples of other issues or problems, typically manifested as time delays at border crossings, repeatedly mentioned by stakeholders include: (1) lack of document standardization; (2) failure to standardize inspection processes; (3) inadequate information and communications systems; (4) manual fee and tariff collection; (5) inconsistency of processes and procedures; and (6) suboptimal cooperation among governmental agencies. Most of these issues can be addressed to some extent by the development of advanced technologies with the objective of allowing ports of entry to become more efficient while being more effective. Three categories of technologies were unambiguously of high priority to port of entry stakeholders: (1) automated documentation; (2) systems integration; and (3) vehicle and cargo tracking. Together, these technologies represent many of the technical components necessary for pre-clearance of freight approaching international ports of entry. Integration of vehicle and cargo tracking systems with port of entry information and communications systems, as well as existing industry legacy systems, should further enable border crossings to be accomplished consistently with optimal processing times.

331

Activities of RILEM Technical Committee: Internal Curing of Concrete and Anticipated Research  

Novel methods of shrinkage mitigation, based on special advanced methods of internal curing (IC), are currently being intensively studied in research groups in several countries. They have been the focus of the State-of-the-Art report prepared by the Technical Committee TC 196-ICC “Internal Curing of Concrete” of the International Union of Laboratories and Experts in Construction Materials, Systems and Structures (RILEM). The authors of this short communication served as a chair (K. Kovler) and secretary (O.M. Jensen) of the TC. The regular and corresponding members were acknowledged RILEM experts in the domain. To account for the different practices and different standards around the world, the TC included representatives from three different world regions: Europe, North America and Asia. Totally more than 30 members from 17 countries contributed in the committee work. Some of them serve in parallel in ACI, JCI (Japan Concrete Institute) and other well-known research associations in the field of concrete science and engineering. Internal curing, as well as external curing, can be classified into two categories: • Internal water curing (sometimes called “water entrainment”), when the curing agent performs as a water reservoir, which gradually releases water, and • Internal sealing, when the curing agent is intended to delay or prevent loss of water from the hardening concrete. The committee addressed both internal water curing and internal sealing, but focused on the first method, which is much more developed than the internal sealing techniques. The State-of-the-Art report (STAR) published by the TC in 2007 covers the present knowledge about principles, technologies and effects of internal curing of concrete. As a part of the TC work an International RILEM Conference was organized: "Volume Changes of Hardening Concrete: Testing and Mitigation", Lyngby, Denmark, 20-23 August 2006. In addition a DTU-RILEM Doctoral Course was held “Concrete Curing: From the Research Lab to the Construction Site”, 13-19 August 2006. One goal of the future research and development in the area of internal curing of concrete would be deeper understanding of the absorption/desorption mechanism of super-absorbent polymers (SAP) introduced into cementitious hardening material. A new RILEM TC on use of SAP in concrete has been recently drafted to follow up on the work of the TC 196-ICC. One of the important instruments for an international cooperation and coordination in further research, development and standardization in the field of Internal Curing of Concrete is a close collaboration with ACI (in particular, with ACI Committee 236 “Materials Science of Concrete”), JCI and other leading international and national research associations. In this sense, it seems to be symbolic to mention that the first meeting of the TC 196-ICC was organized in close cooperation with the ACI in conjunction with one of the ACI conventions (Phoenix, October 2002), and the final communication about the fruits brought by the committee work is being reported in another ACI convention (Puerto-Rico, October 2007).

332

The IAEA Standards for the Radioactive Discharge Control: Present Status and Future Development  

The International Atomic Energy Agency (IAEA) is the organization within the UN family with a statutory mandate to establish standards for the protection of health and environment against ionizing radiation, and to provide for the application of those standards. As part of these functions, the IAEA periodically reviews the status and continued relevance of the standards to the needs of its Member States. Recent work on the development of standards for the radioactive discharge control includes development of practical guidance for setting discharge limits, elaboration on methodology for the radiation protection of non-human species, and preparation of guidance on environmental monitoring for radiation protection purposes. Development of these safety documents is influenced by recent international and regional tendencies, based on social initiatives, to reduce radioactive discharges substantially below levels justified by radiological criteria. The IAEA has developed preliminary guidance on practical aspects of setting discharge limits, which included a review of national regulatory experience in this regard. This review suggested that societal pressures and regulatory practicalities results in discharge controls that were likely to be more restrictive that those that would be implied by formal optimization techniques. Regulatory review of authorizations includes a number of considerations, including predicted doses to members of the critical group, but the suitability of abatement forms a greater part in the decision-making process than allowed for in previous safety guidance. The IAEA has, in recent years, established a programme of work specifically addressing the development of safety standards on assessing the impact of ionizing radiation on non-human species, in co-operation with other relevant international organizations. The main issues arising will be summarised in the paper with the main focus on an exploration of the possible form of future regulatory criteria; the application of biota dose rate data and derived activity concentrations, and their relationship to discharge regulation and derived criteria for human protection. The new Safety Guide on strategies for the Monitoring of Radionuclides in the Environment has been recently developed by the IAEA. Its aim is to establish strategies for radiation monitoring at the source and in the environment coherent with contemporary radiation protection principles. The strategy of monitoring has been developed in relation to: a) control of radionuclide discharges under practice conditions, and b) intervention, such as in cases of nuclear or radiological emergencies or past contamination of areas with long-lived radionuclides. Practical guidance specific to different facilities and situations is being developed in a number of accompanying Safety Reports, both of generic and facility-specific nature. (author)

333

8 CFR 316.20 - American institutions of research, public international organizations, and designations under the...  

...Development Anthropology, Inc. Institute of International Education, Inc. Institute of International Studies, University... Louisiana State University. Massachusetts Institute of Technology. Michigan State University,...

334

Standardizing information exchange towards the end user. Present data models with two way communication over the Internet[Norway]; Standardisering av informasjonsutveksling mot sluttbruker. Aktuelle datamodeller ved toveiskommunikasjon via Internett  

The two-way communication towards the end consumer is in little use so far. There are probably several reasons for this but one important reason may be the lack of standardized interfaces for the information exchange towards the end user. The lack of such standards results in substantial system investment risks for the network companies because the systems may not be developed further and maintained should the deliverer leave the market. The communication channel Internet has expanded quickly and in Norway of today (1999) 25 to 30 % of the households have an Internet connection. The use of existing infrastructure and already tried out technology for information transferrals may contribute to making two-way communication more reasonable and functional. In the report various alternatives of standardized information exchange towards the end users are evaluated. Various formats are discussed with the following demands in mind: 1) Shall be suited for all types of communication media. 2) An international standard followed by everyone. 3) Reliable information transferral and flexible. The focus is on what kind of information is being transferred and how this is organized, and not on how the information is transferred. The discussed alternatives are evaluated both regarding traditional solutions for two- way communication and the use of the Internet. The following format alternatives are discussed: EDIEL/EDIFACT, ODEL(GS2), LonWorks/Echelon, UCA, DLMS/COSEM, COBRA and DCOM. The formats represent communication at various levels but they are mentioned in the report because they are often mentioned as possible standard formats towards the end user: ODEL, DLSM/COSEM and UCA. EDIEL is not suited for this interface. The market for two-way communication systems is international and it does not seem to be practical to establish a joint Norwegian/Swedish standard. The work with establishing one standard should therefore be continued through international standardization organisations. Norway/Sweden should in this context contribute with information regarding formats that may be useful in the end user interface as well (i.e. ODEL). In order to ensure the maintenance of a future system for two-way communication and contribute to standardization in the field, the network companies are requested to demand a full documentation of the end user interface when investing in these types of systems.

335

Development of a high-performance liquid chromatography method for the simultaneous quantitation of glutathione and related thiols.  

The development of drugs with the ability to increase the level of the antioxidant glutathione and related metabolites has become an important research area for many age-related diseases. Here we describe a high-performance liquid chromatography (HPLC) method that uses the thiol-specific, fluorogenic reagent 4-fluoro-7-aminosulfonylbenzofurazan (ABD-F) for the simultaneous determination of total glutathione (GSH), cysteine (Cys), cysteinylglycine (CysGly), and homocysteine (Hcys) in cell culture medium. ABD-F-labeled thiols were separated using an isocratic mobile phase consisting of 14% methanol and 86% 0.1M acetate buffer at pH4.0. The method was validated for linearity, accuracy, and intra- and interday precision, and the lower and upper limits of quantitation (LLOQ and ULOQ, respectively) were determined using a Dionex RF-2000 detector set to medium sensitivity. In addition, the suitability of N-acetylcysteine (NAC) as an internal standard was evaluated by external and internal standard calibration methods. Although both calibration methods showed acceptable linearity (correlation coefficients>0.99) and intra- and interday precision (relative standard deviations=10.2 and 6.6%, respectively), the external standard calibration method performed better in terms of accuracy (recovery=93.7-125%) and also had lower LLOQ values for all analytes (Cys=6.3?M, CysGly=0.8?M, Hcys=0.8?M, and GSH=1.6?M). PMID:22759776

336

Proposed minimal standards for the genus Mycobacterium and for description of new slowly growing Mycobacterium species.  

In accordance with Recommendation 30b of the International Code of Nomenclature of Bacteria, which calls for the development of recommended minimal standards for describing new species, we propose minimal standards for describing the genus Mycobacterium and new slowly growing species of this genus. The minimal standards for assignment of a strain to the genus Mycobacterium include acid-alcohol fastness, a DNA G+C content in the range from 61 to 71 mol%, and mycolic acid detection with characterization of C22 to C26 pyrolysis esters. The recommended minimal standards for describing a new slowly growing Mycobacterium species are based on the results of phenotypic and genomic studies and include the results of the following conventional tests: growth at 25, 30, 33, 37, 42, and 45 degrees C; pigmentation; resistance to isoniazid, thiophene-2-carboxylic acid hydrazide, hydroxylamine, p-nitrobenzoic acid, sodium chloride, thiacetazone, picrate, and oleate; catalase activity; Tween hydrolysis; urease activity; niacin detection; and nitrate reductase, acid phosphatase, arylsulfatase, pyrazinamidase, and alpha-esterase activities. In addition, a mycolic acid profile should be determined, and DNA-DNA hybridization experiments in which the difference between the denaturation temperature of the homologous reaction and the denaturation temperature of the heterologous reaction is determined should be performed. This proposal has been endorsed by the members of the Subcommittee for Taxonomy of the Mycobacteria of the International Committee on Systematic Bacteriology. PMID:1581193

337

[Norms and standards for radiofrequency electromagnetic fields in Latin America: guidelines for exposure limits and measurement protocols].  

New technologies that use electromagnetic fields (EMF) have proved greatly beneficial to humankind. EMF are used in a variety of ways in the transmission of electrical energy and in telecommunications, industry, and medicine. However, some studies have shown that EMF could be detrimental to one's health, having found an association between exposure to EMF on the one hand, and the incidence of some types of cancer as well as behavioral changes on the other. Although so far there is no concrete proof that exposure to low-intensity EMF is hazardous, researchers continue to study the issue in an attempt to reach a consensus opinion and to establish safety standards. While developing and establishing such norms and standards have traditionally been the responsibility of international specialized agencies, national health authorities should take an active part in this process. Currently the Pan American Health Organization is promoting scientific research, often in the form of epidemiologic studies, in order to propose uniform norms and standards. Some Latin American countries, including Argentina, Brazil, Chile, Colombia, Costa Rica, Ecuador, Mexico, Peru, and Venezuela, have already enacted incomplete or partial legislation based on recommended international standards. This article describes the norms established in Latin America and the particular approach taken by each country. PMID:17199914

338

Syntheses of lignin-derived thioacidolysis monomers and their uses as quantitation standards.  

Analytical thioacidolysis releases diagnostic monomers from lignins by selectively cleaving alkyl aryl ether bonds. High yielding syntheses of the three thioacidolysis monomers were developed, and the compounds were used as standards for gas chromatography-mass spectrometry (GC-MS) and gas chromatography-flame ionization detector (GC-FID) quantitation of monomers released from lignocellulosics. First, syringyl, guaiacyl, and p-hydroxyphenyl glycerols were synthesized from the corresponding ethyl cinnamates and used as thioacidolysis substrates to prepare the monomers in high yields. These monomers were then used as standard compounds to measure their GC-MS and GC-FID response factors against two internal standards, 4,4'-ethylenebisphenol and tetracosane. For quantitation, it was shown that 4,4'-ethylenebisphenol is the better internal standard for GC-MS, whereas tetracosane remains the choice for GC-FID. When the obtained response factors were applied, the thioacidolysis monomer yields from white spruce, loblolly pine, poplar, bamboo, and sugar cane bagasse were determined by GC-MS. The obtained results were consistent with those reported in the literature. PMID:22191493

339

Certification testing at the National Wind Technology Center  

The International Electrotechnical Commission is developing a new standard that defines power performance measurement techniques. The standard will provide the basis for international recognition of a wind turbine`s performance primarily for certification, but also for qualification for tax and investment incentives, and for contracts. According to the standard, the power performance characteristics are defined by a measured power curve and by projections of annual energy production for a range of wind conditions. The National Wind Technology Center (NWTC) has adopted these power performance measurement techniques. This paper reviews the results of the NWTC`s first test conducted under the new protocol on the Atlantic Orient Corporation`s AOC 15/50 wind turbine at the NWTC. The test required collecting sufficient data to establish a statistically significant database over a range of wind speeds and conditions. From the data, the power curve was calculated. Then the results from a site calibration procedure determined the flow distortion between winds measured at the turbine location and those measured at the meteorological tower. Finally, this paper discusses the uncertainty analysis that was performed in accordance with the standard. Use of these procedures resulted in the definition of the AOC 15/50`s power curve within about 3 kW.

340

European Commission action aimed at constructing a European regulatory framework; L'action de la Commission europeenne pour un cadre reglementaire europeen  

The challenge of a low-carbon economy provides a new incentive for the development of renewable energies as well as of nuclear energy. The latter calls for a high level of safety and security. The EU has a role in providing a legal framework for this purpose as well as ensuring that these standards are respected internationally. For over 50 years the EURATOM Treaty has offered the legal basis for a wide range of initiatives supporting this policy. The EU has competences under chapter 3, 'Health and Safety', for the establishment of basic safety standards for the protection against ionizing radiation. These have extended beyond the scope of nuclear energy and now include medical exposures as well as natural radiation sources. The latest revision of the BSS-Directive, to be proposed in 2011, was an opportunity for the consolidation of all Community legislation. A ruling of the Court of Justice in 1999 paved the way for the establishment of standards on the safety of nuclear installations. A common vision on this matter was achieved through the creation of a body of European Safety Regulators (ENSREG) and the adoption of a specific Safety Directive in 2009. This new Directive translates internationally agreed safety standards into legally binding EU legislation and strengthens the position of national Regulators. (author)

 
 
 
 
341

APS Performance Summary - Update  

High Energy Density Physics (HEDP) Experiments play an important role in corroborating the improved physics codes that underlie LLNL's Stockpile Stewardship mission. Conducting these experiments, whether on the National Ignition Facility (NIF) or another national facility such as Omega, will require not only improvement in the diagnostics for measuring the experiment, but also detailed knowledge of the as-built target components and assemblies themselves. To assist in this effort, a defined set of well-known reference standards have been built and are being used to quantify the performance of different characterization techniques. Without the critical step of using reference standards for qualifying characterization tools there can be no verification of either commercial or internally-developed characterization techniques and thus there is an uncertainty in the input to the as-built physics codes. In FY03, two reference standards were fabricated and characterized using metrology tools. One of the reference standards was built with a cylindrical geometry and the second reference standard was built with a spherical geometry. The standards were designed for manufacturability, stability, and to provide a range of features that can be measured using NDE methods. Detailed information about these methods has been previously documented.

342

National Imagery Transmission Format (NITF) standard: a government/industry model  

The National Imagery Transmission Format Standard (NITFS) is the collaborative result of a U. S. Government and industry effort to provide a common facility for exchanging imagery and image-associated data among a wide range of legacy, migration, and future intelligence systems. The purpose of the NITFS is to provide a common standard for the transmission of files composed of images, symbols, labels, text, and other information that relate to imagery. NITFS had its genesis in the early 1980s as a vehicle to meet the challenges imposed by a changing military/intelligence paradigm. Early successes spurred increased interest in the standard's evolution. Non-DoD program offices and commercial vendors began to develop NITFS compliant systems and products. The National Imagery Transmission Format (NITF) component of the NITFS was selected as the basis for a North Atlantic Treaty Organization (NATO) Standard Agreement (STANAG) for secondary imagery dissemination. Similarly, the International Standards Organization (ISO) recently accepted a new work item, using the NITF as a point of departure, called the Basic Image Interchange Format (BIIF). Products based on this new standard are expected to be NITF compatible while at the same time providing for increased functionality.

343

Generating benchmarking indicators for employee job satisfaction  

This paper aims to generate benchmarking indicators for employee job satisfaction using a large size sample including various industrial and occupational sectors. Job satisfaction was measured using the Job Satisfaction Scale developed by the Sheffield Institute of Work Psychology and published with a benchmarking manual in 2007. The International Standard Classification of Occupations developed by the International Labour Organization was used to classify occupations into sectors and job titles. The sample of the study consisted of (4076) individuals working in 24 public and private organisations. Statistical outcomes indicated that the managerial job sector has the highest job satisfaction means (M = 4.24, SD = 1.09), while the lowest means went to the craft workers' sector (M = 3.47, SD...

344

A validated HPLC method for determination of Artesunate in bulk and tablet formulation  

The simple, accurate and precise HPLC method for determination of Artesunate in bulk and tablet dosage form has been developed. Quantitation of drug was carried out on Jasco HPLC system with HiQ-SiL C8 column (250 mm ? 4.6 mm i.d.), using acetonitrile: 1 M sodium acetate buffer (pH 3 adjusted with o-phosphoric acid) in the ratio 70: 30 as mobile phase. Method was developed using Artemether as internal standard and UV detector set at 220 nm. Linear concentration range was found to be 250?2500 ?g/mL. The method has been successfully applied to the analysis of drugs in bulk and pharmaceutical formulation. The method was validated with respect to linearity, precision and accuracy as per the International Conference on Harmonisation guidelines.

345

The study of HRM in Spain: the Americanization of Spanish research and the politics of denial?  

The study of HRM in Spain is flourishing. We have seen the major international journals begin to reflect the work of Spanish academics in this area. The standard is high and the international network of Spanish scholars is increasingly developed. This paper attempts to review the work that is published in English and to see how Spanish HRM systems are represented externally. It tries to locate the discussion of the HRM research in Spain within its academic and social context. The authors argue that there are some characteristics marking this debate and development, which suggest that the study of HRM in Spain is hugely Americanized in terms of methods and content. The lack of synergies with sociology and political economy are evident. Moreover, the shortage of rigorous qualitative research...

346

Medical education in the Netherlands  

This paper aims to draw a picture of current medical education in The Netherlands. Based on strong historical roots in the seventeenth century, Dutch medical education has adapted to changing circumstances through the ages. Nowadays, medical education in The Netherlands may be called "modern", according to international standards and schools such as the one in Maastricht serve as examples, nationally and internationally. After considerable redesign of undergraduate education in the 1980s and 1990s, the first decade of the new century shows a revolutionary development of postgraduate medical education, with the introduction of nationwide competency-based training, and mandatory in-training assessments and portfolios for residents. The high level of activity in medical education development ...

347

Rendimentos crescentes e a distribuição internacional de renda/ Increasing returns and the international distribution of income  

Abstract in english The existence of increasing returns in high technology industries assigns a path dependent character to the international division of labor. Rich countries, first entrants in these industries, enjoy permanent advantages that prevent, in a free market environment, the development of such industries in middle-income countries. This dynamics allows the former group of countries to experience a higher growth rate of labor productivity than the latter, and, as a result, increa (more) ses the gap between the workers' standard of living in these countries. It is up to the States of middle-income countries the task of devising development strategies capable of breaking such pattern and improving the international distribution of income.

348

ILO activities in the area of chemical safety.  

The ILO has been active in the area of safety in the use of chemicals at work since the year of its creation in 1919, including the development of international treaties and other technical instruments, the provision of technical assistance to its member States, and the development of chemical safety information systems. The two key ILO standards in this area are the Conventions on safety in the use of chemicals at work (No. 170, 1990), and the Prevention of Major Industrial Accidents (No. 174, 1993). The ILO Programme on occupational safety, health and environment (Safe Work) is currently responsible for ILO chemical safety activities. In the past two decades, most of ILO work in this area has been carried out within the context of inter-agency collaboration frameworks linking the ILO, WHO, UNEP, FAO, UNIDO, UNITAR, and the OECD, including the International Programme on Chemical Safety (IPCS), the Inter-Organisation Programme for the Sound Management of Chemicals (IOMC), and the Intergovernmental Forum on Chemical Safety (IFCS). Apart from the regular development, updating and dissemination of chemical safety information data bases such as the IPCS International Chemical Cards, the elaboration of a Globally harmonized system for the classification and labelling of Chemicals (GHS) has been the most outstanding achievement of this international collaboration on chemical safety. PMID:12909402

349

Non-Exercise Estimation of VO[subscript 2]max Using the International Physical Activity Questionnaire  

Non-exercise equations developed from self-reported physical activity can estimate maximal oxygen uptake (VO[subscript 2]max) as well as sub-maximal exercise testing. The International Physical Activity Questionnaire is the most widely used and validated self-report measure of physical activity. This study aimed to develop and test a VO[subscript 2]max estimation equation derived from the International Physical Activity Questionnaire--Short Form. College-aged males and females (n = 80) completed the International Physical Activity Questionnaire--Short Form and performed a maximal exercise test. The estimation equation was created with multivariate regression in a gender-balanced subsample of participants, equally representing five levels of fitness (n = 50) and validated in the remaining participants (n = 30). The resulting equation explained 43% of the variance in measured VO[subscript 2]max (standard error of estimate = 5.45 ml[middle dot]kg[superscript -1][middle dot]min[superscript -1]). Estimated VO[subscript 2]max for 87% of individuals fell within acceptable limits of error observed with sub-maximal exercise testing (20% error). The International Physical Activity Questionnaire--Short Form can be used to successfully estimate VO[subscript 2]max as well as sub-maximal exercise tests. Development of other population-specific estimation equations is warranted. (Contains 5 tables and 1 figure.)

350

The Second International Standard for Streptomycin  

A batch of highly purified streptomycin sulfate has been examined by nine laboratories in six different countries and has been assayed against the First International Standard for Streptomycin. The material examined has been established as the Second International Standard for Streptomycin, and the ...

351

Standards for transport and storage components established by The Atomic Energy Society of Japan and The Japan Society of Mechanical Engineers  

Since June 1997 the standards/specifications and inspection/certification of various products in Japan have been reviewed by Ministries and Agencies, with the aim of reducing direct government intervention to a necessary minimum and creating a free and fair socio-economic system that is fully opened to the international community and based on the rules of self-responsibility and market principles. Reflecting this policy the administrative regulations which prescribe technical standards as specific requirements have been revised by degrees into performance prescriptions. Detailed provisions in ordinances and notices have been abolished gradually to utilize voluntary standards and rules. In the nuclear energy field voluntary standards are being developed to make up statutory performance requirements by the Atomic Energy Society of Japan (AESJ) and the Japan Society of Mechanical Engineers (JSME) together with other organizations such as the Japan Electric Association, the Thermal and Nuclear Power Engineering Society. These voluntary standards and rules by these organizations have been established in order to maintain openness, transparency, fairness, professionalism and promptness and to promote development and globalization.

352

Evolution of cool-roof standards in the United States  

Roofs that have high solar reflectance and high thermal emittance stay cool in the sun. A roof with lower thermal emittance but exceptionally high solar reflectance can also stay cool in the sun. Substituting a cool roof for a noncool roof decreases cooling-electricity use, cooling-power demand, and cooling-equipment capacity requirements, while slightly increasing heating-energy consumption. Cool roofs can also lower citywide ambient air temperature in summer, slowing ozone formation and increasing human comfort. Provisions for cool roofs in energy-efficiency standards can promote the building- and climate-appropriate use of cool roofing technologies. Cool-roof requirements are designed to reduce building energy use, while energy-neutral cool-roof credits permit the use of less energy-efficient components (e.g., larger windows) in a building that has energy-saving cool roofs. Both types of measures can reduce the life-cycle cost of a building (initial cost plus lifetime energy cost). Since 1999, several widely used building energy-efficiency standards, including ASHRAE 90.1, ASHRAE 90.2, the International Energy Conservation Code, and California's Title 24 have adopted cool-roof credits or requirements. This paper reviews the technical development of cool-roof provisions in the ASHRAE 90.1, ASHRAE 90.2, and California Title 24 standards, and discusses the treatment of cool roofs in other standards and energy-efficiency programs. The techniques used to develop the ASHRAE and Title 24 cool-roof provisions can be used as models to address cool roofs in building energy-efficiency standards worldwide.

353

Project on standards on good behaviour for the civilian nuclear industry; Projet de normes de bonne counduite pour l`industrie nculeaire civile  

Nuclear energy has provoked complex and sometimes heated debates involving politic, economic, scientific and moral issues, objective data alongside irrational feelings, short-term calculations as well as concerns touching on the far-reaching of humanity and the earth. These debates go beyond national borders as it is obvious that even though each country may hold divergent positions regarding the development of nuclear energy, their effects have an international scope, and, therefore, must be taken into account by all nations, even those who do not operate nuclear installations. Whatever conclusion may be drawn from these debates, decisions on nuclear energy are always taken by the political authorities, almost always at the highest level, be it national or international. These political decisions then become the body of legal standards, particularly the regulations which govern how nuclear energy is used. The main standards are for technical and scientific quality, applying to energy resource needs, to the reasons why the nuclear industry should be developed, to radioprotection and nuclear security, to protection of the environment, to radioactive waste management, to information and consulting to the public, to international cooperation, to non-proliferation of atomic weapons and to physical protection of nuclear materials. (author).

354

Speciation and legislation - Where are we today and what do we need for tomorrow?  

In international legislation concerning trace elements in food, in the environment or in occupational health most regulations are based on the total element contents, and are frequently given as maximum limits or guideline levels. In contrast, only few regulations pay attention to the molecular species in which the elements are bound. The international legislation concerning contaminants in food is presently being established in the Coder Alimentarius, which is an independent United Nations organisation under the joint FAO/WHO Food Standards Programme. Development of the Coder General Standard for Contaminants and Toxins in Food provides the framework; for future international legislation on metals as contaminants in food. For certain food additives, which include some essential minerals, speciation is an integral part of the set of specification criteria, because only certain defined chemical compounds are permitted as sources of the essential element. The development of more species-specific analytical and toxicological data, and improved communication with legislators will be necessary before it will become possible to lay down species-specific regulations in all the cases where the specialised scientist will consider it reasonable.

355

QUANTIFICATION OF GALLIUM IN DRIED RESIDUE SAMPLES BY XRF: AN IMPROVED SAMPLE PREPARATION METHOD FOR ANALYZING PLUTONIUM METAL.  

A novel XRF sample preparation method was investigated to quantify the concentration of gallium in plutonium metal and minimize the possibility of contaminating the instrument with radioactive material. To prepare homogenous specimens and to add an internal standard, the plutonium must first be dissolved. The currently established method then entails removing the plutonium by chromatography and analyzing the gallium remaining in solution. In the work presented here, plutonium solution aliquots containing zinc as an internal standard were cast onto Mylar, dried, and analyzed by XRF. Aqueous standards containing gallium and zinc were first cast as dried residues, and these residue standards were analyzed and calibrated. More recently aqueous standards containing plutonium, gallium, and zinc were prepared, cast as dried spots, and calibrated. Very linear calibrations were obtained for both sets of standards when zinc was used as the internal standard (RMS values =1% of the standards concentration range). Hence, this dried residue process appears very promising for quantifying gallium in plutonium metal.

356

75 FR 3471 - International Conference on Harmonisation; Guidance on M3(R2) Nonclinical Safety Studies for the...  

...FDA-2008-D-0470] International Conference on Harmonisation...the auspices of the International Conference on Harmonisation...other drug development resources. DATES: Submit written...Drug Information, Center for Drug Evaluation...Limoli, Office of International Programs...

357

Audit of a Scientific Data Center for Certification as a Trustworthy Digital Repository: A Case Study  

Services that preserve and enable future access to scientific data are necessary to ensure that the data that are being collected today will be available for use by future generations of scientists. Many data centers, archives, and other digital repositories are working to improve their ability to serve as long-term stewards of scientific data. Trust in sustainable data management and preservation capabilities of digital repositories can influence decisions to use these services to deposit or obtain scientific data. Building on the Open Archival Information System (OAIS) Reference Model developed by the Consultative Committee for Space Data Systems (CCSDS) and adopted by the International Organization for Standardization as ISO 14721:2003, new standards are being developed to improve long-term data management processes and documentation. The Draft Information Standard ISO/DIS 16363, "Space data and information transfer systems - Audit and certification of trustworthy digital repositories" offers the potential to evaluate digital repositories objectively in terms of their trustworthiness as long-term stewards of digital resources. In conjunction with this, the CCSDS and ISO are developing another draft standard for the auditing and certification process, ISO/DIS 16919, "Space data and information transfer systems - Requirements for bodies providing audit and certification of candidate trustworthy digital repositories". Six test audits were conducted of scientific data centers and archives in Europe and the United States to test the use of these draft standards and identify potential improvements for the standards and for the participating digital repositories. We present a case study of the test audit conducted on the NASA Socioeconomic Data and Applications Center (SEDAC) and describe the preparation, the audit process, recommendations received, and next steps to obtain certification as a trustworthy digital repository, after approval of the ISO/DIS standards.

358

The international radiation protection: the international actors; La radioprotection internationale: les acteurs internationaux  

The International commission on radiation units and measurements, (ICRU) and UNSCEAR represent the basic knowledge from science. For the international recommendations in radiation protection we find ICRP, the radiological safety standards of IAEA, the Committee of radiation protection and public health of the nuclear energy agency (Nea), the role and recent activities of the ilo concerning the radiation protection of workers and the Who role in radiation protection. About the regulation elaboration for the international standardization in radiation protection we have the international standard organisation (ISO), the alimentarius Codex and the radiation protection, at the European level, the European commission and the directives lay down the basic standards in radiation protection, the scientific and technical committee of the EURATOM treaty (S.T.C.). How to use the regulation is explained trough the international radiation protection association (IRPA), the European ALARA network (E.A.N.) the international cooperation on N.R.B.C. malevolent risk. (N.C.)

359

The International Virtual Observatory: Summary of the first decade  

International Virtual Observatory is a collection of integrated astronomical data archives and software tools that utilize computer networks to create an environment in which research can be conducted. Several countries have initiated national virtual observatory programs that will combine existing databases from ground-based and space-born observatories and make them easily accessible to researchers. As a result, data from all the world's major observatories will be available to all users and to the public. This is significant not only because of the immense volume of astronomical data but also because the data on stars and galaxies have been compiled from observations in a variety of wavelengths: optical, radio, infrared, gamma ray, X-ray and more. Each wavelength can provide different information about a celestial event or object, but also requires a special expertise to interpret. In a virtual observatory environment, all of this data is integrated so that it can be synthesized and used in a given study. The International Virtual Observatory Alliance (IVOA) represents 20 national and international projects working in coordination to realize the essential technologies and interoperability standards necessary to create a new research infrastructure. Russian Virtual Observatory is one of the founders and important members of the IVOA. The International Virtual Observatory project was launched about ten years ago, and its major achievements in science and technology in recent years are discussed in this paper. Standards for accessing large astronomical data sets were developed. Such data sets can accommodate the full range of wavelengths and observational techniques for all types of astronomical data: catalogues, images, spectra and time series. The described standards include standards for metadata, data formats, query language, etc. Services for the federation of massive, distributed data sets, regardless of the wavelength, resolution and type of data were developed. Effective mechanisms for publishing huge data sets and data products, as well as data analysis toolkits and services are provided. The services include source extraction, parameter measurements and classification from data bases, data mining from image, spectra and catalogue domains, multivariate statistical tools and multidimensional visualization techniques. Development of prototype virtual observatory services and capabilities implemented within the existing data centers, surveys and observatories are also discussed. We show that the International Virtual Observatory has evolved beyond the demonstration level to become a real research tool. Scientific results based on end-to-end use of virtual observatory tools are discussed in the paper.

360

Final Report on Jobin Yvon Contained Inductively Coupled Plasma Emission Spectrometer  

A new Inductively Coupled Plasma -- Emission Spectrometer (ICP-ES) was recently purchased and installed in Lab B-147/151 at SRTC. The contained JY Model Ultima 170-C ICP-ES has been tested and compared to current ADS ICP-ES instrumentation. The testing has included both performance tests to evaluate instrumental ability, and the measurement of matrix standards commonly analyzed by ICP-ES at Savannah River. In developing operating procedures for this instrument, we have implemented the use of internal standards and off-peak background subtraction. Both of these techniques are recommended by EPA SW-846 ICP-ES methods and are common to current ICP-ES operations. Based on the testing and changes, the JY Model Ultima 170-C ICP-ES provides improved performance for elemental analysis of radioactive samples in the Analytical Development Section.

 
 
 
 
361

Development and evaluation of Standard Operating Procedures (SOPs) for quality control tests and radiological protection activities in a Nuclear Medicine Service  

The quality management in Nuclear Medicine Services is a requirement of national and international standards. The Brazilian regulatory agency in health surveillance, the Agencia Nacional de Vigilancia Sanitaria (ANVISA), in its Resolucao de Diretoria Colegiada (Collegiate Directory Resolution) no. 38, requires the elaboration of documents describing the technical and clinical routine activities. This study aimed to elaborate, implement and evaluate Standard Operating Procedures (SOPs) for quality control tests and radiological protection activities in the Nuclear Medicine Service of a university hospital. Eighteen SOPs were developed, involving tasks related to dose calibrator, gamma camera, Geiger-Muller detectors and radiological protection activities. The performance of its application was evaluated for a period of six months. It was observed a reduction in 75% of reported operational errors and 42% of the number of reported incidents with contamination by radioactive material. The SOPs were adequate and successful in its application. New procedures involving clinical activities will also be developed and evaluated. (author)

362

EU law and global regulatory regimes: Hollowing out procedural standards?  

This article examines the effects that the reception of decisions of international organizations and bodies in EU law may have in procedural standards followed in EU law and practice, in particular participation. Illustrative examples shed light on the practical interactions between EU and global regulatory systems and their likely negative impact on procedural standards. The author argues that the current EU rules of reception of such decisions are limited in two respects. First, issues of procedural protection are decided by the system of origin, the procedural rules of which may not be as developed as those in force in the EU. Second, rules of reception do not capture the effects of the varied interconnections developed between regulatory regimes at the global and at the EU level. The p...

363

Clinical applications of dosimetry for mIBG therapy.  

Metaiodobenzylguanidine (mIBG), developed 30 years ago, is taken up by tumours expressing the noradrenaline transporter. Radiolabelled with I-123 or I-131, mIBG has become a gold standard for diagnostic imaging of pediatric and adult neuroendocrine cancer. Within a few years of its clinical introduction, I-131 mIBG was found to be an effective palliative treatment with minimal toxicity that in some cases could produce a complete response. The importance of internal dosimetry for I-131 mIBG therapy has been demonstrated by a number of studies showing that absorbed doses delivered to tumours and organs-at-risk from standard and weight-based activities can vary by an order of magnitude. However, significant correlations between the whole-body absorbed dose and myelotoxicity have been demonstrated and studies based on this relationship have enabled treatments to be tailored to the individual. Ongoing developments include patient-specific treatment planning based on tumour dosimetry and cocktails of radionuclides and radiosensitisers. PMID:21386786

364

Secure implementation of cryptographic modules  

The use of cryptographic modules is rapidly expanding throughout the world. Because of this, it is necessary to standardize a security evaluation scheme and to establish a public evaluation and validation program for these modules. Side channel attacks, which extract secret information from the cryptographic module by analyzing power consumption and electromagnetic radiation, are attracting a lot of attention. Research activity on such attacks has intensified recently. However, it is difficult to compare evaluation schemes proposed by different researchers because of differences in the experimental platform or environment. This makes it difficult for other researchers to repeat and verify the results. Therefore, we have developed cryptographic hardware boards and analysis software to serve as a common, uniform evaluation platform for side channel attacks. We have distributed this platform to government, industry, and academic research labs throughout the world in order to facilitate the development of an international standard.   

365

Conceptualizing international art therapy education standards  

Art therapy programs developing around the world need an educational framework to ensure that graduates have a knowledge base and set of skills consistent with peers in other countries. Currently there are many independent education standards offered by art therapy associations in the United Kingdom, United States, Canada, Australia and New Zealand, as well as two international associations. Synthesizing these requirements reveals 12 content areas that may constitute the core of art therapy education. Even within these standards, programs developing around the world need to consider local values related to health, art, therapy and education in order to establish globally relevant and locally meaningful art therapy training programs-Hong Kong and India are offered as examples of how to adap...

366

Effects of national pollution control measures on international competitiveness. Die internationale Wettbewerbswirksamkeit nationaler Umweltschutzmassnahmen  

Together with environmental problems having become more and more urgent since the beginning of the 1970ies, also an intensive economic discussion has set in. The consequences of the tight interconnections of world trade become more and more apparent and further disturbances of the development of international flows of trade and the distribution of labor can be expected if measures to protect the environment are introduced on national levels and not brought into line on an international level. In this volume the author sets the problems into a greater context and discusses the effects on international competitiveness of national environmental objectives and of the instruments to enforce them. The opinion, which is presented as the result of this study, to bring national standards largely into line and to put them into practice without effects on international competition is meant as an orienting line for those responsible for economic policy. The international comparison of objectives and measures of control provides manifold information and insight into the problems involved.

367

Toward an international standard for PCR-based detection of Escherichia coli O157. Part 1. Assay development and multi-center validation.  

As part of a major European research project, a diagnostic PCR assay, including an internal amplification control, was developed and validated in a collaborative trial for the detection of Escherichia coli O157. The assay is based on amplification of sequences of the rfbE O157 gene. The collaborative trial, including 12 international laboratories, was carried out in two phases: phase (a) was performed with identical PCR reagents, including the internal control, provided by the sending laboratory; phase (b) was performed on the same samples and internal control but using in-house PCR reagents of own choice. Phase (a) showed an inclusivity (detection of target strains) of 96.8% and the exclusivity (negative response from nontarget strains) was 100%. The overall performance resulted of phase (a) in an accordance of 98.8, concordance of 98.6, and a concordance odds ratio of 1.11. Phase (b) results showed an accuracy of 100% with all partners and by using different polymerase types and thermocycler models. This indicates that the assay, under consideration as an international standard, was just as reproducible between laboratories, as repeatable within a laboratory. The assay is taken further for validation on carcass-rinse samples. PMID:14607420

368

Toward an international standard for PCR-based detection of Escherichia coli O157 - Part 1. Assay development and multi-center validation  

As part of a major European research project, a diagnostic PCR assay, including an internal amplification control, was developed and validated in a collaborative trial for the detection of Escherichia coli O157. The assay is based on amplification of sequences of the rJbE O157 gene. The collaborative trial, including 12 international laboratories, was carried out in two phases: phase (a) was performed with identical PCR reagents, including the internal control, provided by the sending laboratory; phase (b) was performed on the same samples and internal control but using in-house PCR reagents of own choice. Phase (a) showed an inclusivity (detection of target strains) of 96.8% and the exclusivity (negative response from nontarget strains) was 100%. The overall performance resulted of phase (a) in an accordance of 98.8, concordance of 98.6, and a concordance odds ratio of 1.11. Phase (b) results showed an accuracy of 100% with all partners and by using different polymerase types and thermocycler models. This indicates that the assay, under consideration as an international standard, was just as reproducible between laboratories, as repeatable within a laboratory. The assay is taken further for validation on carcass-rinse samples.

369

Internal standard versus external standard calibration: an uncertainty case study of a liquid chromatography analysis  

Abstract in english Traditionally, in the cigarettes industry, the determination of ammonium ion in the mainstream smoke is performed by ion chromatography. This work studies this determination and compares the results of this technique with the use of external and internal standard calibration. A reference cigarette sample presented measurement uncertainty of 2.0 ?g/cigarette and 1.5 ?g/cigarette, with external and internal standard, respectively. It is observed that the greatest (more) source of uncertainty is the bias correction factor and that it is even more significant when using external standard, confirming thus the importance of internal standardization for this correction.

370

High-performance liquid chromatographic determination and pharmacokinetic study of cefepime in goat plasma and milk after pre-column derivatization with Hg(I).  

A highly sensitive and selective HPLC method with UV detection was developed for the determination of cefepime in goat plasma and milk. The proposed method was based on the complexation of cefepime with Hg(I) ions that imparts the high selectivity of the proposed method with enhancement of the sensitivity which enabled the analysis of cefepime in complex matrices such as plasma and milk. Detection was performed at 263 nm, using cefuroxime sodium as an internal standard. Chromatographic separation of cefepime and the internal standard was achieved with Aqua RP-C(18) column using methanol/triethylamine-acetate buffer, pH 3.5 (18:82, v/v) as mobile phase at a flow rate of 1 mL/min. Linear detector responses were observed spanning the range of 1.3-20 ?g/mL. The LOD for standard cefepime was 0.43 ?g/mL, whereas the LOD for cefepime in goat plasma was 0.84 ?g/mL and the corresponding value in goat milk was 1.1 ?g/mL. No interference from endogenous substances in plasma and milk was observed. The developed HPLC method has been successfully applied for the pharmacokinetic study of cefepime in goat plasma and milk, for the first time, after a single intramuscular injection of 50 mg cefepime/kg body weight. PMID:20730834

371

Understanding and Informing the Policy Environment: State-Level Renewable Fuels Standards  

Renewable fuels standard (RFS) policies are becoming a popular public policy mechanism for developing the market for renewable fuels in the transportation sector. During the past decade, U.S. states and several countries began implementing these more market-based (less command and control) policies to support increased biofuels production and use. This paper presents an overview of current and proposed U.S. state-level policies, as well as selected electric sector policies and international fuel standard policies. Current U.S. state-level renewable fuel policies list drivers including an improved economy and environment, as well as fuel self-sufficiency. Best practices and experience from an evaluation of renewable portfolio standards (RPS) in the United States and international RFS policies can inform U.S. state-level policy by illustrating the importance of policy flexibility, binding targets, effective cost caps, and tradable permits. Understanding and building on the experiences from these previous policies can improve the policy mechanism and further develop a market for renewable fuels to meet the goals of improved economy, environment, and fuel self-sufficiency.

372

Methods for measurements of energy and emissions related to motor vehicles: Identification of needs for improvements  

The official methods in use today for emission testing of vehicles and engines were primarily developed for the characterisation of exhaust emissions from motor vehicles fuelled with petrol or diesel oil. The setting of new lower emission standards will make it difficult to obtain sufficient accuracy, using the present systems, for the quantification of exhaust emissions in the future. Development of new emission control technology and improved fuels has made it possible to meet these more stringent standards. Consequently new emission standards will lead to a need for new and improved methodologies and new instrumentation for the characterisation of the emissions from vehicles/engines/fuels. The present report comprises a discussion and comments on questions related to improved methods for emission measurements. The report is based on a study of the literature, site visits to laboratories and research institutes etc in the US and a meeting with representatives of the EU Commission, carried out during the spring of 2001. The conclusions and recommendations in the pre-study report are summarised in sub titles: General, regulated emissions, unregulated emissions, greenhouse gases and fuel consumption. Since the questions and problems discussed have an international connection they should be discussed in an international forum. However, before such discussions can be organised the problems related to measurement of emissions and fuel consumption must be more extensively studied than in this pre-study.

373

FY 1999 project on the development of new industry support type international standards. Standards development of chemical analysis and non-destructive inspection methods for pure titanium metals; 1999 nendo shinki sangyo shiengata kokusai hyojun kaihatsu jigyo seika hokokusho. Junchitan no shiken hyoka hoho no hyojunka  

To propose it to ISOTC79 and ISOTC135, study was conducted for standardization of chemical analysis method and non-destructive inspection method for industrial use pure titanium. As the chemical analysis method, the inductively coupled plasma atomic emission spectrometry which has good detection limit was developed, and at the same time, the standardization of spark and/or glow discharged atomic emission spectrometry was developed. As the non-destructive inspection method, developmental study on the following was carried out: surface defect inspection method of pure titanium metals by laser scanning inspection system or CCD camera; internal defect inspection of pure titanium sheet and coil by plate wave ultrasonic inspection method; internal defect inspection of pure titanium bar by eddy current method; inspection of very small leakage of pressurized fluid through defects in pure titanium pipe and tube by pressure differential testing method. As a result of the study, standards of system performance and tolerance were determined in analysis of Pd, Si, Al, Cu, Mo, Zr, Nb, Ta and Y. Further, analytical conditions and application ranges of the spark discharged atomic emission spectrometry were made definite in terms of 19 elements including Mn, Fe, Ni, Cr, Sn, Pb, Si, Al, V, Cu, Mo, Zr, Nb, Ta, Co, B, Y, C and W. (NEDO)

374

Determination of diethanolamine or N-methyldiethanolamine in high ammonium concentration matrices by capillary electrophoresis with indirect UV detection: application to the analysis of refinery process waters.  

Alkanolamines such as diethanolamine (DEA) and N-methyldiethanolamine (MDEA) are used in desulfurization processes in crude oil refineries. These compounds may be found in process waters following an accidental contamination. The analysis of alkanolamines in refinery process waters is very difficult due to the high ammonium concentration of the samples. This paper describes a method for the determination of DEA in high ammonium concentration refinery process waters by using capillary electrophoresis (CE) with indirect UV detection. The same method can be used for the determination of MDEA. Best results were achieved with a background electrolyte (BGE) comprising 10 mM histidine adjusted to pH 5.0 with acetic acid. The development of this electrolyte and the analytical performances are discussed. The quantification was performed by using internal standardization, by which triethanolamine (TEA) was used as internal standard. A matrix effect due to the high ammonium content has been highlighted and standard addition was therefore used. The developed method was characterized in terms of repeatability of migration times and corrected peak areas, linearity, and accuracy. Limits of detection (LODs) and quantification (LOQs) obtained were 0.2 and 0.7 ppm, respectively. The CE method was applied to the determination of DEA or MDEA in refinery process waters spiked with known amounts of analytes and it gave excellent results, since uncertainties obtained were 8 and 5%, respectively. PMID:15338092

375

Determination of diethanolamine or N-methyldiethanolamine in high ammonium concentration matrices by capillary electrophoresis with indirect UV detection: application to the analysis of refinery process waters  

Alkanolamines such as diethanolamine (DEA) and N-methyldiethanolamine (MDEA) are used in desulfurization processes in crude oil refineries. These compounds may be found in process waters following an accidental contamination. The analysis of alkanolamines in refinery process waters is very difficult due to the high ammonium concentration of the samples. This paper describes a method for the determination of DEA in high ammonium concentration refinery process waters by using capillary electrophoresis (CE) with indirect UV detection. The same method can be used for the determination of MDEA. Best results were achieved with a background electrolyte (BGE) comprising 10 mM histidine adjusted to pH 5.0 with acetic acid. The development of this electrolyte and the analytical performances are discussed. The quantification was performed by using internal standardization, by which triethanolamine (TEA) was used as internal standard. A matrix effect due to the high ammonium content has been highlighted and standard addition was therefore used. The developed method was characterized in terms of repeatability of migration times and corrected peak areas, linearity, and accuracy. Limits of detection (LODs) and quantification (LOQs) obtained were 0.2 and 0.7 ppm, respectively. The CE method was applied to the determination of DEA or MDEA in refinery process waters spiked with known amounts of analytes and it gave excellent results, since uncertainties obtained were 8 and 5%, respectively. (orig.)

376

Sustainability of gamma-ray isotopics evaluation codes  

In November 2005, the international workshop 'Gamma Evaluation Codes for Plutonium and Uranium Isotope Abundance Measurements by High-Resolution Gamma Spectrometry: Current Status and Future Challenges' was held in Karlsruhe, Germany. Some of the main issues discussed during the November 2005 meeting were related to concerns voiced by international inspectorate authorities such as the International Atomic Energy Agency (IAEA), the European Atomic Energy Community (EURATOM), and the Brazilian-Argentine Agency for Accounting and Control of Nuclear Materials (ABACC) about the standardization and sustainability of gamma-ray isotopic analysis codes that are commonly used during safeguards inspections. A follow-up international workshop was conducted in Oak Ridge, TN in 2008. This workshop was in response to needs expressed by the international safeguards community during the Karlsruhe meeting and recommendations made under Action Sheet 14; a cooperative effort between the U. S. Department of Energy and ABACC. The purpose of the Oak Ridge workshop was to bring code developers and end users together to better understand the capabilities and limitations of the codes; to discuss mechanisms to ensure these codes are sustained and quality tested; and to ensure updates or revisions are performed in a controlled manner. During an Action Sheet 14 meeting held in Rio de Janeiro, Brazil in which the IAEA and EURATOM participated as observers, and in subsequent meetings of the European Safeguards Research and Development Association (ESARDA), all parties agreed that the regional working group initially established under the DOE/ABACC cooperation should be expanded to an international working group. The purpose of the international working group is to provide a forum to exchange information, discuss technical developments, and validate and test the various codes. However, progress to formally establish the working has been slowed by a lack of dedicated funding and competing priorities within the various international organizations. Recently, the ESARDA Nondestructive Assay Working Group established a dedicated website for the International Working Group on Gamma Spectrometry Techniques (1 WG-GST). In this paper, we will explore specific steps that should be taken to strengthen this working group's ability to affect development of a common testing platform and address concerns regarding applicability, sustainability and version control for these important codes.

377

Evaluación del grado de ajuste de las revistas científicas españolas de ciencias de la salud a las normas internacionales de presentación de publicaciones periódicas/ Assesing compliance of Spanish scientific biomedical journals to international standards for the presentation of periodicals  

Abstract in spanish FUNDAMENTO: Se evalúa el cumplimiento, por parte de 205 revistas científicas españolas de ciencias de la salud, de las normas internacionales de presentación de publicaciones periódicas, con el fin de mejorar su calidad informativa, puesto que la normalización constituye un elemento importante en el éxito del proceso de transferencia de la información científica. MÉTODOS: Las revistas se identificaron a través de cinco bibliografías impresas y cuatro bases de (more) datos bibliográficas. Se controlaron 136 preceptos extraídos de las normas internacionales de presentación de publicaciones periódicas emitidas por la International Standardization Organization (86%) y de recomendaciones generadas por la UNESCO, el International Committee of Medical Journal Editors, el Council of Biology Editors y EJ Huth (14%). Para cada parámetro se valoraron tres niveles de evaluación (Inclusión, Presentación y Ubicación), por lo que el número total de ítemes evaluados fue de 342. RESULTADOS: El grado de normalización de las revistas biomédicas españolas estudiadas fue del 33,5% ± 8,5. Destacan por su buen ajuste los parámetros referidos a la identificación de la revista en las páginas del texto y al sumario del fascículo. Los aspectos más descuidados se concentran en el volumen y sumario analítico. Las revistas peor normalizadas son las auspiciadas por empresas y organismos de gestión. Las revistas anuales son las mejor estandarizadas. CONCLUSIONES: El bajo nivel de normalización que resulta no se debe a un deficiente cumplimiento generalizado de todos los parámetros sino más bien al incumplimiento completo de algunos de los mismos, en concreto: las normas que regulan el sumario analítico y la cubierta, sumario e índices de volumen. Para conseguir una mayor normalización de las revistas se propone un cambio en la política de difusión de las normas, la elaboración de guías y manuales para la confección de publicaciones científicas y el desarrollo de programas docentes con vistas a la educación de autores, directores, editores, bibliotecarios y documentalistas. Abstract in english BACKGROUND: Because standardization is important to ensure the successful transfer of scientific information, compliance with international standards for the presentation of periodicals in 205 Spanish biomedical journals, with the aim of improving their quality as instruments of information transfer, is evaluated. METHODS: Journals were identified by consulting five printed bibliographies and four electronic databases. A total of 136 parameters of evaluation for the prese (more) ntation of periodicals derived from ISO (International Standardization Organization) standards (86%) and recomendations published by UNESCO, the International Committee of Medical Journal Editors, The Council of Biology Editors, and EJ Huth (14%) were evaluated. Three features (inclusion, presentation and location) were recorded for most data item, and the total number of items studied was 342. RESULTS: The rate of compliance with standards in Spanish biomedical journals was 33.5% ± 8,5 (DE). Compliance was highest for items related with the identification of the journal in the text pages and the issue contents list. The lowest rates of compliance were found for items related the volume and the abstract sheet. The worst standardized journals were those published by private firms and public administration organizations. As a group, journals published annually were the best standardized. CONCLUSIONS: The low rate of compliance with standards did not reflect inadequate compliance with all items, but was rather the result of complete noncompliance with particular standards, especially those relating to the abstract sheet, volume front cover, volume contents list and volume index. To improve compliance a change in the policies governing the availability of standards, the preparation of guides and manuals for scientific periodical publishing, and the development of training programs aimed at authors, editors, publishers, librarians and information scientists, is suggested.

378

Technical Study Addresses a Key Challenge to Harmonizing U.S. and International PV Module Standards (Fact Sheet)  

NREL builds community and industry support by addressing concerns voiced by key standards organizations. Photovoltaic (PV) manufacturers in the United States test the safety of their products using standards developed through consensus processes. Because U.S. PV module safety standards are not aligned with international standards, manufacturers must test their modules twice - and sometimes maintain separate product lines. By meeting with standards organizations such as the Solar ABCs and Underwriters Laboratories (UL), National Renewable Energy Laboratory (NREL) leaders have worked to identify different stakeholders priorities and concerns. UL, specifically, has expressed concern that the international standards do not address all possible risks. For example, new encapsulant materials could soften at high temperatures and frameless modules could slide apart, exposing live electrical parts or allowing glass to fall on a person below. The deformation of a solid material under the influence of mechanical stresses is known as 'creep.' Current module qualification tests are limited to 85 C, whereas modules can, for short times, reach 105 C outdoors. In response to UL's concern, NREL designed and executed an experiment to compare on-sun and accelerated rates of creep for modules fabricated with various encapsulants, including some that have low melting points. Objectives were to (1) evaluate the potential for creep in outdoor exposure, (2) provide guidance on the risks and design needs with thermoplastic materials, and (3) provide a basis for modifying standards to account for materials with potential to creep. The study tested experimental materials with eight representative encapsulants in both outdoor and indoor (chamber) exposure. The study found that modules with materials that were expected to creep did so in the indoor exposure, but not in most outdoor environments and mounting configurations. The results provide a basis for defining an accelerated test needed to give confidence that the modules will not slide apart on hot days. The proposal for IEC 61730 Part 1 exposes modules for 200 hours to a temperature between 105 C and 110 C. NREL is collaborating with UL representatives, and U.S. and international standards appear to be closer to harmonization.

379

[Informatics in the Croatian health care system].  

Informatization process of the Croatian health care system started relatively early. Computer processing of data of persons not covered by health insurance started in 1968 in Zagreb. Remetinec Health Center served as a model of computer data processing (CDP) in primary health care and Sveti Duh General Hospital in inpatient CDP, whereas hospital administration and health service were first introduced to Zagreb University Hospital Center and Sestre Milosrdnice University Hospital. At Varazdin Medical Center CDP for health care services started in 1970. Several registries of chronic diseases have been established: cancer, psychosis, alcoholism, and hospital registries as well as pilot registries of lung tuberculosis patients and diabetics. Health statistics reports on healthcare services, work accidents and sick-leaves as well as on hospital mortality started to be produced by CDP in 1977. Besides alphanumeric data, the modern information technology (IT) can give digital images and signals. Communication in health care system demands a standardized format of all information, especially for telemedicine. In 2000, Technical Committee for Standardization in Medical Informatics was founded in Croatia, in order to monitor the activities of the International Standardization Organization (ISO) and Comite Européen de Normalisation (CEN), and to implement their international standards in the Croatian standardization procedure. The HL7 Croatia has also been founded to monitor developments in the communication standard HL7. So far, the Republic of Croatia has a number of acts regulating informatization in general and consequently the informatization of the health care system (Act on Personal Data Confidentiality, Act on Digital Signature, Act of Standardization) enacted. The ethical aspect of data security and data protection has been covered by the Code of Ethics for medical informaticians. It has been established by the International Medical Informatics Association (IMIA), and the Croatian Society of Medical Informatics (CSMI) has translated it into Croatian and published it on its website. Based on a survey of medical staff attitudes toward health care system informatization, the Croatian health system appears to be ready for informatization. The only requirement is that the present and future health care providers have appropriate medical informatics education, proper computer equipment at their workplace, and an opportunity to participate in the development and/or improvement of the health information system. One of the EU health strategy priorities is the improvement of health information and knowledge. It means that integrated health information systems are required, i.e. systems able to provide key information on health and health care system to the politicians, health professionals and public in general. PMID:16095187

380

Study on the standardization of hospital information system for medical image information sharing  

As the adoption of PACS and hospital information system among university hospitals and hospital level institutions grows bigger, the need of sharing and transferring medical information among medical institutions is rising. For the medical information, which is saved in the hospital medical system, to be transferred within the same hospital, domestic, or foreign medical institutions, a standard protocol is necessary. But realistically, most of the domestic hospitals do not abide by H7L which is the HIS standard and so, information transferring is not possible as of present. As such, the purpose of this research is to implement the information between HIS and PACS to an international standard by constructing HL7 messages through HL7 Interface, which will eventually make possible information transferring between different hospitals. Our research team has developed a method which will make the PACS equip hospitals that do not follow HL7 standard which will make possible to transfer information between HIS and PACS through HL7 Message. By constructing message files, which follow the form of HL7 Message in the HL7 Interface, they can be transferred to PACS through the ftp protocol. The realization of the HIS/OCS Interface through HL7 enables data transferring between domestic and foreign medical institutions possible by implementing the international standard in the PACS and HIS data transferring process. The HL7 that our research team has developed made patient data transfer between medical institutions possible. The Interface is for a specific system model and in order for the data transfer between different systems to be realized, interfaces that are fit for each system must be needed. If the Interface is improvised and implemented to each hospital's information system, the data sharing among medical institutions can be broadened.

 
 
 
 
381

Unattended ground sensors standards working group: transforming the unattended sensor paradigm  

The FY 10-15 Defense Intelligence Guidance (DIG) issued by the Under Secretary of Defense for Intelligence (USDI) tasked the Defense Intelligence Agency (DIA) to generate an Unattended Ground Sensors (UGS) roadmap. The roadmap was intended to encapsulate a broad understanding of ongoing and planned UGS development and deployment activities across the Department of Defense (DoD). This understanding supports an evolution to a cross-DoD and intelligence community (IC) integrated approach for acquiring and fielding UGS. To further this approach, a memorandum signed by the Deputy Under Secretary of Defense for Technical Collection & Analysis endorsed the creation of an UGS Standards Working Group (SWG). The UGS SWG is working across the defense community via its newly established Technology Focus Groups (TFGs) to address the specifics of the open architecture standards for unattended sensors (OASUS). Derived from the Terra Harvest-developed, open, integrated battlefield UGS architecture, OASUS separates the UGS system into fundamental components and standardizes internal and external interfaces to optimize interoperability. The TFGs are looking specifically at software component architecture, wired and wireless interfaces, and physical and logical user interfaces. This paper details the progress of these focus group efforts and invites participation in ongoing development of unattended sensor standards that advance the technology beyond the familiar pattern of controller, trigger, and camera.

382

Japanese Virtual Observatory (JVO) as an advanced astronomical research environment  

We present the design and implementation of the Japanese Virtual Observatory (JVO) system. JVO is a portal site to various kinds of astronomical resources distributed all over the world. We have developed five components for constructing the portal: (1) registry, (2) data service, (3) workflow system, (4) data analysis service (5) portal GUI. Registry services are used for publishing and searching data services in the VO, and they are constructed using an OAI-PMH metadata harvesting protocol and a SOAP web service protocol so that VO standard architecture is applied. Data services are developed based on the Astronomical Data Query Language (ADQL) which is an international VO standard and an extension of the standard SQL. The toolkit for building the ADQL-based service is released to the public on the JVO web site. The toolkit also provides the protocol translation from a Simple Image Access Protocol (SIAP) to ADQL protocol, so that both the VO standard service can be constructed using our toolkit. In order to federate the distributed databases and analysis services, we have designed a workflow language which is described in XML and developed execution system of the workflow. We have succeeded to connect to a hundred of data resources of the world as of April 2006. We have applied this system to the study of QSO environment by federating a QSO database, a Subaru Suprim-Cam database, and some analysis services such a SExtractor and HyperZ web services. These experiences are described is this paper.

383

Do stronger intellectual property rights promote seed exchange: evidence from U.S. seed exports?  

Abstract With increased private investment in crop breeding research in the developed world, intellectual property rights have gained importance in seed sector. Trade Related Aspects of Intellectual Property Rights (TRIPS)-plus provisions included in recent free trade agreements between the developed and developing countries show a tendency of the developed world to impose their high standards for protection of plant intellectual property on the developing world. While stronger intellectual property rights can increase international exchange in seed, market power effect can lead to a reduction in exports of seed to foreign markets. This article estimates the impact of intellectual property rights on U.S. seed exports. The estimation is performed at a crop level using Heckman selection mode...

384

Web services at the IRIS DMC to support integration of data sets  

At the IRIS Data Management Center (DMC) we have developed web service interfaces to almost all of the data types we manage. These service interfaces provide access to raw time series data and associated metadata. In addition, we offer services that apply processing to the data before it is sent to the user. Whenever possible we chose open and recognized standards. The services themselves use only a simple subset of widespread web service technologies and methods, ensuring the widest possible support in programming languages and operating systems. To promote easier access to seismological and other geophysical data we are coordinating our web service developments with national and international parters. We are working within the Federation of Digital Seismograph Stations (FDSN) to define web service standards for international seismological data centers. Additionally we are working with key partners in Europe to complete the initial implementation of these international standards. Within the United States we have started coordinating with other data centers for related geophysical data types (e.g. geodetic) with the intention of facilitating cross-domain data discovery and use. The overall goal of these efforts is to make data more open, easily found and used by research scientists regardless of the repository in which any given data resides. To foster integration across geophysical domains the IRIS DMC is also making information available in the form of higher level products. These products often are more easily understood by a wider audience than the more esoteric seismographic time series. The support of products will support better integration of data sets. We will present the status of our web service developments and the related coordination efforts in addition to the next steps and vision for the future.

385

Development of Integration in Manufacturing : Interoperability of CAD Standards and Robotics in CIME  

Current international developments in the broad field of Product Data Technology are advancing rapidly and are leading up to new levels of technology in product model definition, product model communications, enterprise integration and cooperation. These developments will be of strategic significance to all manufacturing industries.International standardization based on the product model definition standard STEP (ISO10303) is playing a key role in promoting a modern approach to Product Data Technology. The initial release of STEP, consisting of twelve essential parts, has recently been approved and published as International Standard. The introduction of STEP based software and its application in industry is thus on the verge of being broadly realized.In this initial release, STEP mainly addresses geometric and kinematic product model data properties whichare sufficient 'static' model features for covering the area of conventional CAD design. However, the developing areas of advanced CAD design, simulation, and program-ming of dynamic systems are not yet covered by STEP. A static model description is not sufficient to cover such model features, and this implies for instance, that STEP must be extended to cope with descriptions of functional behavior of products.In the robotics area, Computer Aided Robotics (CAR) systems for design, off-line programming, and simulation are currently increasing their model features with new topics, such as multi-body dynamics, realistic motion planning and control. From dealing with pure geometric motions of mechanisms described by shape and kinematics, these computer based systems can now handle more complete system models in order to obtain more reliable designs, and provide simulation results for more feasible robot off-line programming.

386

Fiscal 1997 report on the results of the international standardization R and D. International standards for computers/manikins; 1997 nendo seika hokokusho kokusai hyojun soseigata kenkyu kaihatsu. Computer manikin ni kansuru kokusai hyojun kikaku  

Through the development of computer manikins (CM) which assess human adaptability to products and environments, a draft for international standardization was worked out to propose to ISO. A draft for the international standardization was presented to ISO through a development of `a structure model` changing based on human attributes, a study of `a motion model` enabling changes in posture and movement, a study of `an evaluation model` evaluating attainment ranges and ecodynamic loads, and a development of `computer functions` realizing the above-mentioned functions. The development of CM having the following characteristics: a function to reproduce `the structure model` based on the ISO7250 human body dimensional measuring values which were regulated in items for the human body dimensional measuring, a function to change posture/movement based on the joint movable range data, a function to evaluate geometrical human adaptability such as attainment ranges. As a plug-in to Autodesk Mechanical Desktop 2.0, the above-mentioned functions were realized, and the modular structure platform was constructed which enables the wide-range cross-industry option and functional expansion by the advance of CM. 7 refs., 41 figs., 18 tabs.

387

Development of the REFPROP database and transport properties of refrigerants. Final report  

This task consisted of developing Version 6.0 of the NIST Thermodynamic and Transport Properties of Refrigerants and Refrigerant Mixtures Database (REFPROP), entailing a complete revision of this database. This program is based on the most accurate pure fluid and mixture models currently available. The database development is further divided into the development of a graphical user interface and the development of Fortran subroutines which implement the property models. Three models are used for the thermodynamic properties of pure components, depending on the availability of data. The first is the modified Benedict-Webb-Rubin (MBWR) equation of state. It is capable of accurately representing the properties of a fluid over wide ranges of temperature, pressure, and density. The MBWR equation is the basis for the current international standard for the properties of R123. The second high-accuracy pure-fluid equation of state is written in terms of reduced molar Helmholtz free energy. This Helmholtz energy model is the basis for the international standard formulation for R134a. The third pure-fluid model is the extended corresponding states (ECS) model of Huber and Ely (1994). It is used for fluids with limited experimental data. The database calculates seventeen thermodynamic and transport properties, including surface tensions of pure fluids and mixtures. Commercialized blends, such as R407C and R410A, are predefined in the interface and are listed in a table.

388

Annual report of the activities of health physics in JAERI in 2000. April 1, 2000 - March 31, 2001  

This annual report summarizes the activities in fiscal year 2000 concerned with radiation protection which cover environmental monitoring of the facilities, radiation protection of workplace and workers, individual monitoring, maintenance of monitoring instruments, and their technical development, carried out at the establishments of Tokai, Naka, Takasaki, Oarai, Kansai and Mutsu of JAERI. The report also covers the research activities of 4 research laboratories, i.e., Radiation Risk analysis, Internal Dosimetry, External Dosimetry and Calibration Standards and Measurement, in Department of Health Physics in Tokai Research Establishment. There are no occupational exposure and effluent release recorded exceeding the prescribed limits for effective dose equivalent and radioactive concentrations for gaseous release and liquid waste. 10th International Conference of the International Radiation Protection Association (IRPA) was held in May in 2000, and lots of cooperative activities for supporting the conference, such as presentations, attending the organizing or executive committees, etc. were made. Cooperative works concerning measurement of radiation dose and air concentration of large amount of monazite found in Saitama and Nagano prefectures were carried out and also for advice for the measures. The data such as radioactive air concentration or shielding factors obtained by the research and development for internal dosimetry and external dosimetry was adopted in the prescriptions of the regulations concerning prevention from radiation hazard in Japan. (author)

389

Evaluation of fourth international standard for whole cell pertussis vaccine.  

Whole cell pertussis vaccine is still widely used in many countries. An International Standard is needed for its potency control. The Third International Standard for Pertussis Vaccine was prepared about 40 years ago and its replacement was recommended by the Expert Committee for Biological Standardisation (ECBS) of the WHO. Material in ampoules coded 94/532 was prepared as a candidate replacement and has been evaluated in international collaborative studies which consisted of two parts. The first part, to assess the suitability of the candidate standard by comparing it with the Second International Standard for Pertussis Vaccine (IS2) involved 14 laboratories in 11 countries. The second part to compare the candidate standard with the Third International Standard for Pertussis Vaccine (IS3) involved 16 laboratories in 14 countries. Since 1995 various other studies have included the international standards and the results of these are also considered in assessing likely continuity of the IU for potency of whole cell pertussis vaccine. The preparation in ampoules coded 94/532 was adopted by the WHO ECBS in October 2006 as the 4th International Standard for whole cell pertussis vaccine and assigned an activity of 40 IU per ampoule on the basis of the studies reported here. PMID:20709568

390

Multi-element quantification of ancient/historic glasses by laser ablation inductively coupled plasma mass spectrometry using sum normalization calibration  

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) for quantitative analysis of ancient/historic glasses is subject to calibration issues which have been addressed in this work. Since ancient/historic glasses have widely ranging matrix compositions, a complementary analysis by an alternative method is generally employed to determine at least one major element which can be used as an internal standard. We demonstrate that such a complementary analysis is unnecessary using a so-called sum normalization calibration technique (mathematically formulated) by simultaneous measurement of 54 elements and normalizing them to 100% [w/w] based on their corresponding oxide concentrations. The crux of this approach is that by assuming a random internal standard concentration of a particular major oxide, e.g. SiO{sub 2}, the normalization algorithm varies the internal standard concentration until the cumulated concentrations of all 54 elemental oxides reach 100% [w/w]. The fact that 54 elements are measured simultaneously predetermines the laser ablation mode to rastering. Nine glass standards, some replicating historic compositions, were used for calibration. The linearity of the calibration graphs (forced through the origin) represented by the relative standard deviations in the slope were between 0.1 and 6.6% using SiO{sub 2} as an internal standard. This allows high-accuracy determination of elemental oxides as confirmed by good agreement between found and reported values for major and minor elemental oxides in some synthetic glasses with typical medieval composition (European Science Foundation 151 and 158). Also for trace elemental concentrations of lanthanides in a reference glass (P and H Developments Ltd. DLH7, a base glass composition with nominally 75 {mu}g g{sup -1} elements added) accurate data were obtained. Interferences from polyatomic species and doubly charged species on the masses of trace elements are possible, depending on the base composition of the glass, with Ba and Sb glasses showing potential interferences on some lanthanides. We showed that they may be reduced to a great extent by using an Octopole Reaction System although the overall sensitivity decreases which may be a problem for some low-level determinations.

391

Multi-element quantification of ancient/historic glasses by laser ablation inductively coupled plasma mass spectrometry using sum normalization calibration.  

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) for quantitative analysis of ancient/historic glasses is subject to calibration issues which have been addressed in this work. Since ancient/historic glasses have widely ranging matrix compositions, a complementary analysis by an alternative method is generally employed to determine at least one major element which can be used as an internal standard. We demonstrate that such a complementary analysis is unnecessary using a so-called sum normalization calibration technique (mathematically formulated) by simultaneous measurement of 54 elements and normalizing them to 100% [w/w] based on their corresponding oxide concentrations. The crux of this approach is that by assuming a random internal standard concentration of a particular major oxide, e.g. SiO2, the normalization algorithm varies the internal standard concentration until the cumulated concentrations of all 54 elemental oxides reach 100% [w/w]. The fact that 54 elements are measured simultaneously predetermines the laser ablation mode to rastering. Nine glass standards, some replicating historic compositions, were used for calibration. The linearity of the calibration graphs (forced through the origin) represented by the relative standard deviations in the slope were between 0.1 and 6.6% using SiO2 as an internal standard. This allows high-accuracy determination of elemental oxides as confirmed by good agreement between found and reported values for major and minor elemental oxides in some synthetic glasses with typical medieval composition (European Science Foundation 151 and 158). Also for trace elemental concentrations of lanthanides in a reference glass (P&H Developments Ltd. DLH7, a base glass composition with nominally 75 microg g(-1) elements added) accurate data were obtained. Interferences from polyatomic species and doubly charged species on the masses of trace elements are possible, depending on the base composition of the glass, with Ba and Sb glasses showing potential interferences on some lanthanides. We showed that they may be reduced to a great extent by using an Octopole Reaction System although the overall sensitivity decreases which may be a problem for some low-level determinations. PMID:19463554

392

Revision of the Euratom Basic Safety Standards Directive-current status  

The European Commission is currently developing a revised Euratom Basic Safety Standards (BSS) Directive covering two major objectives: the consolidation of existing Euratom Radiation Protection legislation and the revision of the Euratom BSS. The consolidation will merge the following five Directives into one single Directive: the BSS Directive, the Medical Exposures Directive, the Public Information Directive, the Outside Workers Directive and the Directive on the Control of high-activity sealed radioactive sources and orphan sources. The revision of the Euratom BSS will take account of the latest recommendations by the International Commission on Radiological Protection and shall improve clarity of the requirements where appropriate. It is planned to introduce more binding requirements ...

393

Electrospun tubular scaffolds: On the effectiveness of blending poly(-caprolactone) with poly(3-hydroxybutyrate-co-3-hydroxyvalerate)  

Abstract Tissue engineering can effectively contribute to the development of novel vascular prostheses aimed to overcome the well-known drawbacks of small-diameter grafts. To date, poly(-caprolactone) (PCL), a bioresorbable synthetic poly(-hydroxyester), is considered one of the most promising materials for vascular tissue engineering. In this work, the potential advantage of intimate blending soft PCL and hard poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), a polymer of microbial origin, has been evaluated. Nonwoven mats and small-diameter tubular scaffolds of PCL, PHBV, and PCL/PHBV were fabricated by means of electrospinning technique. Mechanical properties and suture retention strength were investigated according to the international standard for cardiovascular implants. Biologica...

394

Recent Advances on Scalable Video Coding  

Scalable video coding offers efficient video transmission to a variety of display devices over heterogeneous and error-prone networks. Scalable video coding has been strenuously researched in recent years and state-of-the-art international coding with scalability has been standardized as SVC, which is an extension of H.264/AVC. This paper summarizes the recent advanced research that has been done for improving the quality and reducing the complexity of scalable video coding (including SVC), as well as for improving the quality assessment techniques. It is intended to give researchers a critical, technical overview of what is required to develop more efficient scalable video coding in the future.   

395

Prognostic scoring systems in MDS  

Prognostic scoring systems in myelodysplastic syndromes are useful tools in order to get in idea on the expected course of the disease and offer patients a risk adapted treatment. Several good scores have been developed, the international prognostic scoring system (IPSS) being the gold standard for 15 years, now validated and refined. As more and more patients receive therapy and drugs are approved, the major goal for future projects must be the identification of predictive parameters and scoring systems in order to predict the response and outcome after specific treatments.

396

Analysis of Tebuconazole and Tetraconazole Enantiomers by Chiral HPLC-MS/MS and Application to Measure Enantioselective Degradation in Strawberries  

A rapid and sensitive enantioselective method for the determination of tebuconazole and tetraconazole enantiomers in strawberry has been developed. The enantiomers were resolved by high-performance liquid chromatography on a cellulose tris (3-chloro-4-methylphenylcarbamate) (Lux Cellulose-2) column using methanolâ??0.1% formic acid solution (70:30, v/v) as mobile phase. The chiral liquid chromatographic separation was combined with an extract/cleanup procedure known as the quick, easy, cheap, effective, rugged, and safe (QuEChERS) method. High-performance liquid chromatography-tandem mass spectrometry with electrospray ionization was then used for qualitative and quantitative determination of the enantiomers of tebuconazole and tetraconazole. Hexaconazole was used as an internal standard. ...

397

Performance assessment overview for subseabed disposal of high level radioactive waste  

The Subseabed Disposal Project (SDP) was part of an international program that investigated the feasibility of high-level radioactive waste disposal in the deep ocean sediments. This report briefly describes the seven-step iterative performance assessment procedures used in this study and presents representative results of the last iteration. The results of the performance are compared to interim standards developed for the SDP, to other conceptual repositories, and to related metrics. The attributes, limitations, uncertainties, and remaining tasks in the SDP feasibility phase are discussed.

398

Boiling heat transfer correlations for refrigerant mixtures flowing inside micro-fin tubes  

Based on experimental results of ternary non-azeotropic refrigerant mixture R417A flowing and boiling in one smooth and two internally grooved horizontal tubes with different geometrical parameters, a boiling heat transfer correlations was developed for refrigerant mixtures flowing inside micro-fin tubes by applying the enhancement factor in the present modified-Kattan model which was modified by the experimental data of R417A in a smooth tube. The comparison between the calculation and the experimental results indicates that the prediction by the present correlations is in good agreement with the experiment of refrigerant mixtures inside different microfin tubes with a standard deviation of ?30% for vapor qualities below 80%.

399

Analysis of Tebuconazole and Tetraconazole Enantiomers by Chiral HPLC-MS/MS and Application to Measure Enantioselective Degradation in Strawberries  

A rapid and sensitive enantioselective method for the determination of tebuconazole and tetraconazole enantiomers in strawberry has been developed. The enantiomers were resolved by high-performance liquid chromatography on a cellulose tris (3-chloro-4-methylphenylcarbamate) (Lux Cellulose-2) column using methanol???0.1% formic acid solution (70:30, v/v) as mobile phase. The chiral liquid chromatographic separation was combined with an extract/cleanup procedure known as the quick, easy, cheap, effective, rugged, and safe (QuEChERS) method. High-performance liquid chromatography-tandem mass spectrometry with electrospray ionization was then used for qualitative and quantitative determination of the enantiomers of tebuconazole and tetraconazole. Hexaconazole was used as an internal standard. ...

400

SQL All-in-One For Dummies  

The soup-to-nuts guide on all things SQL!. SQL, or structured query language ,  is the international standard language for creating and maintaining relational databases. It is the basis of all major databases in use today and is essential for the storage and retrieval of database information. This fun and friendly guide takes SQL and all its related topics and breaks it down into easily digestible pieces for you to understand. You'll get the goods on relational database design, development, and maintenance, enabling you to start working with SQL right away!: Provides an overview of the SQL lan

 
 
 
 
401

Simulations of Dense Stellar Systems with the AMUSE Software Toolkit  

We describe AMUSE, the Astrophysical Multipurpose Software Environment, a programming framework designed to manage multi-scale, multi-physics simulations in a hierarchical, extensible, and internally consistent way. Constructed as a collection of individual modules, AMUSE allows computational tools for different physical domains to be easily combined into a single task. It facilitates the coupling of modules written in different languages by providing inter-language tools and a standard programming interface that represents a balance between generality and computational efficiency. The framework currently incorporates the domains of stellar dynamics, stellar evolution, gas dynamics, and radiative transfer. We present some applications of the framework and outine plans for future development of the package.

402

Validation of the MycoAlign system for Mycobacterium spp. identification  

Validation of the MycoAlign assay, a newly developed Mycobacterium spp. identification system based on internal transcribed spacer-1 sequencing, was performed using 50 acid-fast bacilli (AFB)?positive clinical laboratory specimens. Forty-three (86%) diagnostic-level results were obtained, including 38 Mycobacterium spp. and 5 other AFB-positive genera. Three isolates (6%) had suboptimal identity scores with high probability (81?87% identity score). Four (8%) mixed-pattern results were obtained. Forty-five (90%) observations were concordant with the species identification by standard methods, including all controls.

403

Internal environmental protection audits: a suggested guide for US Department of Energy facilities  

This manual has been prepared for use by any DOE facility as an aid for conducting an internal environmental-protection audit. The manual is organized in modular format, with each module covering a separate area of environmental protection. The questions within each module were developed from existing DOE orders, executive orders, federal statutes, and Environmental Protection Agency (EPA) regulations issued pursuant to specific environmental legislation. A bibliography of such legislation is included at the end of this section. Each module also includes questions about a facility's use of industrial standards of practice.

404

High-spectral brightness pump sources for diode-pumped solid state lasers  

The development of on-chip grating stabilized semiconductor lasers for diode pumped solid state lasers is discussed. The diode lasers, specifically at wavelengths of 808nm, 976nm, and 1532nm are stabilized via internal gratings to yield a typical center wavelength tolerance of +/- 1nm, FWHM of CW and QCW operation of conduction cooled bars, stacks, and fiber coupled modules. Simulations show that on-chip stabilized pump sources yield performance improvements over standard pumping schemes. A comparison in laser performance is shown for typical DPSS configuration.

405

Liquid chromatography-mass spectrometric assay for quantitation of the short-chain fatty acid, 2,2-dimethylbutyrate (NSC 741804), in rat plasma  

2,2-Dimethylbutyrate (DMB) is a potential treatment for thalassemia and hemoglobinopathies. To facilitate pharmacokinetic evaluation of DMB, we developed an LC-MS assay and quantitated DMB in plasma of rats after an oral dose of 500mg/kg. After acetonitrile protein precipitation, DMB and dimethylvaleric acid (DMV) internal standard were derivatized to benzylamides, chromatographed on a Hydro-RP column with acetonitrile, water, and 0.1% formic acid, and detected by electrospray positive-mode ionization mass spectrometry. The assay was accurate (97-107%) and precise (3.4-6.2%) between 100 and 10,000ng/mL. Recovery from plasma was >62%. Plasma freeze-thaw and room temperature stability were acceptable.

406

Liquid chromatography-mass spectrometric assay for quantitation of the short-chain fatty acid, 2,2-dimethylbutyrate (NSC 741804), in rat plasma.  

2,2-Dimethylbutyrate (DMB) is a potential treatment for thalassemia and hemoglobinopathies. To facilitate pharmacokinetic evaluation of DMB, we developed an LC-MS assay and quantitated DMB in plasma of rats after an oral dose of 500mg/kg. After acetonitrile protein precipitation, DMB and dimethylvaleric acid (DMV) internal standard were derivatized to benzylamides, chromatographed on a Hydro-RP column with acetonitrile, water, and 0.1% formic acid, and detected by electrospray positive-mode ionization mass spectrometry. The assay was accurate (97-107%) and precise (3.4-6.2%) between 100 and 10,000ng/mL. Recovery from plasma was >62%. Plasma freeze-thaw and room temperature stability were acceptable. PMID:18155649

407

Use of Yttrium Phosphate as a Coprecipitant for Separation/Concentration of Lanthanoids  

A useful method to separate/concentrate lanthanoids was developed based on a rapid coprecipitation technique using yttrium phosphate. Lanthanoids, which were quantitatively coprecipitated at pH 3 with yttrium phosphate, could be readily determined by inductively coupled plasma atomic emission spectrometry with indium used as an internal standard element. The detection limits ranged from 0.0003 ?g (Yb, Lu) to 0.0099 ?g (Er) in 100 mL of sample solutions. The proposed method was applicable to the separation/concentration of lanthanoids in NIST SRM 1515 (apple leaves).   

408

Quantitative analysis of orthorhombic and tetragonal lead monoxide mixtures using internal standard raman spectroscopy  

A Raman spectroscopic method has been developed for the quantitative analysis of mixed oxide materials for orthorhombic and tetragonal phases of PbO. The technique employs an Sb/sub 2/O/sub 3/ internal standard for improved analytical reliability. Samples mixed with KBr are pelletized onto a pure KBr support substrate. The sample pellets are rotated during analysis to minimize irradiation induced alteration or damage. Linear responses for both o-PbO and t-PbO throughout the entire concentration range have been observed. The presence of metallic Pb, which is a Raman inactive material, does not appear to interfere significantly with the linearity of the response.

409

Analysis of the implementation of the radiological protection to the schedules of Nursery and Medicine of the UAEM; Analisis de la implementacion de la proteccion radiologica a los programas de Enfermeria y Medicina de la UAEM  

In this work a presentation of the content of a plan of studies is made directed to the preparation and familiarization of human resources in medicine with applications of ionizing radiations. The plan of studies has been developed with the objective of fulfilling the established training program for the National Commission of Nuclear Safety and Safeguards, as well as to that required by the Secretary of Health with respect to the execution of the Mexican Official Standards corresponding, international recommendations, and to that suggested by the training guides emitted by the General Direction of Training and Production of the Secretary of the Work and Social Forecast. (Author)

410

Morphology of preimaginal stages of Calliphora vicina Robineau-Desvoidy, 1830 (Diptera, Calliphoridae): A comparative study  

A comparative morphological study of preimaginal stages (larvae and pupae) of Calliphora vicina Robineau-Desvoidy, 1830 is presented. The entomological samples came from laboratory colonies bred under controlled environmental conditions (25^oC and 60% relative humidity). In this study, a recently published technique to clear Diptera larvae for light microscopy and a standard protocol for scanning electron microscopy were used. For the morphological comparison of larval instars I, II and III, and pupae of C. vicina, different larval regions (cephalic, thoracic and abdominal, including anal division), as well the internal chitinised cephalopharyngeal skeleton, were considered separately. Our results focus on showing the changes observed throughout development for the most important structure...

411

Centralized resource planning and Yardstick competition  

Multidivisional and decentralized firms often operate inefficiently. In most cases, central management's instruments to influence its branches' behavior are limited. Although relative performance evaluation has been argued to be of great use in defining incentive mechanisms, such approaches cannot be transferred easily to internal performance management. We approach this issue by changing the perspective of performance evaluation. Based on the recently introduced CRA-DEA model, we develop a new super-efficiency measure that enables to establish purposive intra-organizational incentive mechanisms. By means of a numerical example, analyzing the performance of a German retail bank, the applicability of our measure is shown and compared to standard DEA models. Centralized super-efficiency seem...

412

Parallel distributed processing: explorations in the microstructure of cognition. Volume 1. Foundations  

The fundamental principles, basic mechanisms, and formal analyses involved in the development of parallel distributed processing (PDP) systems are presented in individual chapters contributed by leading experts. Topics examined include distributed representations, PDP models and general issues in cognitive science, feature discovery by competitive learning, the foundations of harmony theory, learning and relearning in Boltzmann machines, and learning internal representations by error propagation. Consideration is given to linear algebra in PDP, the logic of additive functions, resource requirements of standard and programmable nets, and the P3 parallel-network simulating system.

413

Merchant marine nuclear-powered vessels  

The history of civil nuclear-powered vessels development in Russia is highlighted. Advantages of nuclear propulsion for icebreakers operating in the Arctic are discussed. The operation of nuclear-powered icebreakers and the nuclear lighters-aboard ship in the Arctic has changed the situation on the Northern Sea Way. The all year round navigation there now is a reality. The reliability, safety and ecological cleanness of nuclear-powered vessels are discussed. The necessity of internationally recognized standards, rules and codes for safe operation of nuclear-powered trade vessels is underlined. (orig.) 3 refs.

414

A conceptual framework for information technology governance effectiveness in private organizations  

Purpose - The purpose of this paper is to develop a conceptual framework that examines information technology (IT) governance effectiveness, its determinants, and its impacts on private organizations. Design/methodology/approach - The research draws on extant literature in IT governance, strategic information systems planning, strategic alignment maturity, information systems security, business and IT alignment, International Organization for Standardization in information systems, and organizational performance to identify determining factors for IT governance effectiveness, IT governance effectiveness factors, and organizational performance. Findings - The results of review suggest 14 propositions and five factors grouped into determinants including organizational demographics, informati...

415

Improved method for gas-liquid chromatographic determination of clopidol in chicken tissues.  

A sensitive and specific gas-liquid chromatographic (GLC) method has been developed for determining low levels of clopidol in chicken tissues. Clopidol is extracted from the tissues with methanol, and cleaned up on an alumina column and an anion exchange resin column with 0.1% acetic acid--methanol as eluate. Clopidol is methylated with diazomethane, and then determined by GLC. 2,4-Dinitro-1-chlorobenzene is used as an internal standard. The method is applicable to levels as low as 2 ppb in chicken tissues. Recoveries of 2--20 ppb clopidol added to tissues averaged 87% for muscle, 84% for liver, 80% for kidney, and 76% for fat. PMID:7451382

416

Biodynamics of the human body under whole-body vibration: Synthesis of the reported data  

Identification of most probable ranges of biodynamic responses of the human body exposed to whole-body vibration is essential for developing effective integrated human-machine system design tools, improved vibration mitigation devices and frequency-weighting for exposure assessment. The international standard, ISO-5982 (2001), defines such ranges for very limited conditions, namely for body seated without a back support and exposed to vertical vibration. The reported data on biodynamic responses of the seated and standing human body exposed to whole-body vibration along different directions and the associated experimental conditions are systematically reviewed in an attempt to identify datasets that are likely to represent comparable and practical postural and exposure conditions. Synthese...

417

Analysis of the anthraquinones aloe-emodin and aloin by gas chromatography/mass spectrometry.  

A procedure was developed for the determination of low levels of the anthraquinones aloe-emodin and aloin A (barbalin) in aloe products based on gas chromatography/mass spectrometry (GC/MS) of the trimethyl silyl (TMS) derivatives of these analytes in the presence of Chrysophanol used as internal standard. The method was used to analyze several aloe based commercial products (liquids, gels and solids). Wide variation in the level of these anthraquinones was observed among the different products. The method had a sensitivity of 0.005 ppm of aloe-emodin and 0.05 ppm of aloin. PMID:15531290

418

Determination of 19 drugs of abuse and metabolites in whole blood by high-performance liquid chromatography?tandem mass spectrometry  

A high-performance liquid chromatography (LC)?tandem mass spectrometry (MS/MS) method has been developed and validated for the determination of 19 drugs of abuse and metabolites and used in whole blood. The following compounds were included: amphetamine, methylenedioxyamphetamine, methylenedioxyethylamphetamine, methylenedioxymethamphetamine, methamphetamine, cocaine, benzoylecgonine, morphine, 6-acetylmorphine, codeine, methadone, buprenorphine, norbuprenorphine, ketobemidone, tramadol, O-desmethyltramadol, zaleplone, zolpidem, and zopiclone. The sample pretreatment consisted of solid-phase extraction using mixed-mode columns (Isolute Confirm HCX). Deuterated analogues were used as internal standards for all analytes, except for ketobemidone and O-desmethyltramadol. The analytes were sepa...

419

Using a CRIS for e-Infrastructure: e-Infrastructure for Scholarly Publications  

Scholarly publications are a major part of the research infrastructure. One way to make output available is to store the publications in Open Access Repositories (OAR). A Current Research Information System (CRIS) that conforms to the standard CERIF (Common European Research Information Format) could be a key component in the e-infrastructure. A CRIS provides the structure and makes it possible to interoperate the CRIS metadata at every stage of the research cycle. The international DRIVER projects are creating a European repository infrastructure. Knowledge Exchange has launched a project to develop a metadata exchange format for publications between CRIS and OAR systems.