Purpose: Radiotherapy (RT) has been the predominant local treatment for Ewing's sarcoma of bone at the University of Florida. Twice-daily hyperfractionated RT was initiated in 1982 to improve local control and functional outcome. This retrospective review compares the results of once-daily vs. twice-daily RT in patients with primary Ewing's sarcoma of an extremity, with emphasis on functional outcome. Methods and Materials: Between June 1971 and January 1990, 37 patients were treated at the University of Florida for nonmetastatic Ewing's sarcoma of bone with a primary lesion in an extremity. Three patients underwent amputation. Of 34 patients treated with RT, 31 had RT alone and 3 had a combination of RT and local excision. Before 1982, 14 patients received once-daily RT; since 1982, 17 patients have received twice-daily RT. Doses of ...
Radiotherapeutic results of the Ewing sarcoma of the long tubular bones in 140 pediatric patients aged 3-16 are analyzed with the respect to different methods of irradiation. Three-field irradiation, the fields being located at 120 deg to one another with daily irradiation of all three fields at a focal dose of 2 Gy, was found superior in treatment of primary neoplasm. It is stressed that the disease termination mainly depends on the efficiency of primary neoplasm treatment, as the neoplasm reccurence generally is followed by metastases. Radiation load is calculated for maximal irradiation area of soft tissues in children.
Summary Objective- To evaluate the role of prophylactic trimethoprim-sulfamethoxazole (co-trimoxazole) antibacterial prophylaxis in reducing morbidity and mortality in HIV-infected post-natal women in southern Africa. Methods- Double-blind placebo-controlled trial. HIV-infected women with WHO stage 2 or 3 HIV disease who had recently delivered in the Department of Obstetrics and Gynaecology at the University Teaching Hospital, Lusaka, Zambia were randomised to receive daily co-trimoxazole (cotox) or matched placebo daily for the duration of the trial. Participants were followed up for a minimum of 1-year. Primary outcome measures were mortality from any cause or hospital admission and serious adverse events. Results- Of 600 women randomised, follow-up information was available from 355 (18...
Abstract Mammalian teeth exhibit incremental structures representing successive forming fronts of enamel at varying time scales, including a short daily increment called a cross striation and a long period called a stria of Retzius, the latter of which, in humans, occurs on average every 8-9 days. The number of daily increments between striae is called the repeat interval, which is the same period as that required to form one increment of bone, i.e. the lamella, the fundamental - if not archetypal - unit of bone. Lamellae of known formation time nevertheless vary in width, and thus their measures provide time-calibrated growth rate variability. We measured growth rate variability for as many as 6 years of continuously forming primary incremental lamellar bone from midshaft femur histologic...
Atrial fibrillation (AF) is common after coronary artery bypass grafting (CABG) and increases the morbidity and cost. Amiodarone reduces AF after CABG. Ranolazine, an antianginal agent, also prolongs atrial refractoriness and inhibits after depolarizations and triggered activity; effects that could decrease AF after CABG. The present study compared amiodarone versus ranolazine for the prevention of AF after CABG. A retrospective cohort study of patients undergoing CABG at Aspirus Hospital from June 2008 to April 2010. The patients received either amiodarone (400 mg preoperatively followed by 200 mg twice daily for 10 to 14 days) or ranolazine (1,500 mg preoperatively followed by 1,000 mg twice daily for 10 to 14 days). The primary end point was any identified AF after CABG. A total of 393 ...
Simultaneous exposures of rats and hamsters to inhaled radon daughters, with and without uranium ore dust, were performed daily for five months. Pulmonary pathology developing in 6 to 13 mo after cessation of daily exposures included interstitial fibrosis, emphysema, epithelial hyperplasia, squamous metaplasia, and malignant neoplasia. Rats showed a greater variety and more severe response to these uranium mine inhalation exposures than did hamsters. Inhalation of radon daughters with uranium ore dust displayed the site of greatest damage, including squamous carcinoma, from the nasopharynx to the lungs. Sixty percent of the rats exposed to radon daughters with ore dust developed primary pulmonary carcinomas, providing an appropriate short-term experimental animal model for investigation of respiratory tract carcinogenesis in uranium miners.
Local control of Ewing's sarcoma was analysed in a series of 67 patients treated by surgery and/or radiotherapy as well as combination chemotherapy. Radiotherapy was employed with or without surgery in 60 patients and produced an overall local control rate of 55%; complete excision of the primary lesion seemed to be beneficial. There was a marked variation in control rates depending on the site of the primary lesion: limb 85%, rib 53%, pelvis 31% and other sites 33%.Primary tumours greater than 10 cm in diameter were significantly less likely to be controlled. Using daily fractions of approximately 180 cGy, total doses in excess of 6000 cGy seem more likely to produce serious late morbidity amd may not increase the local control rate. No cases of second malignancy arising in irradiated tissue have been observed to date, but one patient developed acute lymphoblastic leukaemia. (author).
Objective: The aim of this study was to compare symptoms and anterior segment tolerability with short-term (3-day) administration of once-daily timolol hemihydrate 0.5%, timolol maleate in sorbate 0.5%, and generic timolol maleate gel-forming solution 0.5% in the treatment of glaucoma and/or ocular hypertension. Methods: In this prospective, randomized, double-masked, active-controlled, 3-period crossover pilot study, eligible patients had primary open-angle, pigmentdispersion, or exfoliation glaucoma, and/or ocular hypertension in >=1 eye; had a best corrected visual acuity of 1.0 or better in each eye, as measured using the Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity testing chart; were receiving 1 glaucoma medication; and had an untreated intraocular pressure (IOP) ...
This double-blind, multicenter, randomized placebo-controlled study evaluated the antihypertensive efficacy and safety of nebivolol, a selective beta1-adrenoreceptor blocker with vasodilating effects, in patients with mild to moderate hypertension (sitting diastolic blood pressure [SiDBP] > or =95 mm Hg and < or =109 mm Hg). A total of 909 patients were randomized to receive placebo or nebivolol 1.25, 2.5, 5, 10, 20, or 40 mg once daily for up to 84 days. The primary end point was the change in trough SiDBP from baseline to study end. Nebivolol significantly reduced trough SiDBP (8.0-11.2 mm Hg compared with 2.9 mm Hg with placebo; P<.001) and trough sitting systolic blood pressure (a 4.4-9.5-mm Hg decrease compared with a 2.2-mm Hg increase [corrected] with placebo; P< or =.002). The overall adverse event experience was similar in the nebivolol (46.1%) and placebo (40.7%) groups (P=.273). Once-daily nebivolol ...
The specific goals of this research are to (1) determine daily and seasonal variability of seawater pCO{sub 2} partial pressure of CO{sub 2} and NO{sub 3} in Middle Atlantic Bight (MAB) waters; (2) estimate seasonal CO{sub 2} fluxes between the MAB shelf and the atmosphere; and (3) determine the primary controls of surface seawater pCO{sub 2} in this coastal system. During the first phase of the DOE-OMP (1992-1995) we developed the Submersible Autonomous Moored Instrument for CO{sub 2} (SAMI-CO{sub 2}) which is designed to measure seawater CO{sub 2} on ocean moorings for extended periods.
Purpose The primary objective of this sub-study, undertaken as an extension to the previously reported phase-I study, was to explore the feasibility, tolerability and pharmacokinetics (PK) of belinostat when administered by the oral route. Preliminary pharmacodynamic (PD) studies were also performed to enable comparison of the biological effects of the oral and intravenous formulations. Patients and methods Oral belinostat was administered in a range of doses and schedules (once, twice or thrice daily), on either day 1 or days 1?5, of the second or a subsequent treatment cycle in 15 patients who were included in the phase-I trial of intravenous belinostat. Serial blood samples were collected for PK and PD (histone acetylation) analyses, and the results compared with corresponding analyses ...
Systemic sclerosis (SSc) is a disorder characterized by skin thickness and vasculopathy. The objective of the study was to evaluate the therapeutic effect and safety of the association of pentoxyphylline and vitamin E in SSc patients. Twelve SSc patients (American College of Rheumatology criteria) enrolled this 24-week open-label study. Patients received daily 800?mg of pentoxyphylline and 800?UI of vitamin E and were evaluated at 4-week interval. The primary efficacy endpoint was the change in Modified Rodnan Skin Score (MRSS) at week 24. Nine diffuse SSc patients treated 6?months with cyclophosphamide were used as a historical control group. The mean age of the treated group was 43.6?years, and ten of 12 (84%) patients were women. Their mean MRSS reduced from 25.7 to 18.7 (p?=?0.03) at 1...
Summary A prospective and randomized trial design is of utmost interest when it comes to evaluating new developments in the management of cardiovascular medicine. By defining the primary end point and a profound related statistic new therapeutic options can be tested with an adequate number of patients. The course of the trial is supervised by a Clinical Events Committee and a Data and Safety Monitoring Board. Registries are promising tools for describing how the results of clinical trials are translated into daily practice. Their drawbacks include lack of control of the clinical endpoints and their uniform definition and lack of a control group. There are numerous examples from cardiology of the limited usefulness of data obtained from registry studies with their often unexpected results ...
Summary Background Sorafenib is an oral multikinase inhibitor that blocks cell proliferation via the ERK pathway and angiogenesis via the VEGF pathway. This phase II trial was conducted to determine the efficacy and tolerability of sorafenib for the treatment of patients with metastatic urothelial cancer (UC) who had not had prior chemotherapy for advanced disease. Patients and Methods Seventeen chemo-na?ve UC patients with adequate performance status and organ function were treated with sorafenib 400?mg twice daily on a continuous basis until progression or unacceptable toxicity. The primary endpoint was objective tumor response rate as measured by RECIST criteria. Secondary endpoints included rate of prolonged stable disease (>3?months), time to progression, median and 1?yr survival and ...
The registration of secondary cosmic ray neutrons is a convenient tool for the investigation of primary cosmic ray variations and for meteorological effects as well. At present a large network of neutron monitors exists, aiming at studies of cosmic ray variations which are related to interplanetary conditions and geomagnetic activity. At the same time cosmic ray variations may be related to some atmospheric processes. In this connection, using the data from two neutron monitors (a standard and a lead free one), a gamma detector from Moscow station and lead free neutron monitor at BEO Moussala, we studied the correlations between rain flows and neutron flux. In this study we used daily averages on the basis of 10 min data for the neutron flux, corrected for barometric pressure and data from local meteo-stations. The preliminary analysis indicates a correlation between rain flows and neutron flux in several cases. To explain observable ...
This book deals with organizations that operate in high hazard industries, such as the nuclear power, aviation, oil and chemical industry organisations. The society puts a great strain on these organisations to rigorously manage the risks inherent in the technology they use and the products they produce. In this book, an organisational psychology view is taken to analyse what are the typical challenges of daily work in these environments. The analysis is based on a literature review about human and organisational factors in safety critical industries, and on the interviews of Finnish safety experts and safety managers from four different companies. In addition to this, personnel interviews conducted in the Finnish nuclear power plants are utilised. The authors come up with eight themes that seem to be common organizational challenges cross the industries. These include e.g. how does the personnel understand the risks and what is the right level for rules and ...
BackgroundThe objective of this study was to develop and validate a daily electronic Endometriosis Pain and Bleeding Diary (EPBD) for assessing treatment-related changes in endometriosis...Full Text Available
The purpose of this study was to examine relationships between weather and outdoor physical activity (PA). An online weather source was used to obtain daily max temperature [DMT], precipitation, and...Full Text Available
Adaptive radiation therapy (ART) is the incorporation of daily images in the radiotherapy treatment process so that the treatment plan can be evaluated and modified to maximize the amount of radiation...Full Text Available
ObjectivesThe objectives of this study were to describe the levels of daily spiritual experiences in community-dwelling older adults, to compare levels of spiritual...Full Text Available
The performance of five well-known photosynthesis-light equations is compared by presenting a wide range of solutions in the form of dimensionless nomographs for the case where photosynthetically available radiation (PAR) reduces exponentially down the water column and is distributed sinusoidally through the photoperiod. These provide a simple means of calculating daily photosynthesis at any depth (e.g. at a benthic layer), or through a water column, avoiding the need to perform complex integrations. An examination is made of the accuracy of common approximate methods for calculating daily photosynthesis, assuming constant PAR. For optically deep water a modification is proposed to Talling's planimetric solution, to enable daily photosynthesis to be calculated more accurately, yet simply, over the whole range of possible PAR values. The errors induced by approximating the daily PAR distribution ...
New comparative tests on two different types of solar collectors are presented in this paper. A standard glazed flat plate collector and an evacuated tube collector are installed in parallel and tested at the same working conditions; the evacuated collector is a direct flow through type with external compound parabolic concentrator (CPC) reflectors. Efficiency in steady-state and quasi-dynamic conditions is measured following the standard and it is compared with the input/output curves measured for the whole day. The first purpose of the present work is the comparison of results in steady-state and quasi-dynamic test methods both for flat plate and evacuated tube collectors. Besides this, the objective is to characterize and to compare the daily energy performance of these two types of collectors. An effective mean for describing and analyzing the daily performance is the so called input/output diagram, in which the collected solar energy is ...
We explore a possibility that the daily sea-level pressure (SLP) over South Korea responds to the high-speed solar wind event. This is of interest in two aspects: First, if there is a statistical association this can be another piece of evidence showing that various meteorological observables indeed respond to variations in the interplanetary environment. Second, this can be a very crucial observational constraint since most models proposed so far are expected to preferentially work in higher latitude regions than the low latitude region studied here. We have examined daily solar wind speed ${\\rm V}$, daily SLP difference ${\\rm \\Delta SLP}$, and daily ${\\rm \\log(BV^{2})}$ using the superposed epoch analysis in which the key date is set such that the daily solar wind speed exceeds 800 ${\\rm kms^{-1}}$. We find that the daily ${\\rm \\Delta SLP}$ averaged ...
Stereotactic radiosurgery (SRS) precisely delivers high-dose radiation to a small target (usually less than 3-4 cm in diameter), in a single session with steep dose-fall, employing various radiation methods. SRS provides good tumor control for small brain metastases from various primary cancers, with minimal untoward effects on surrounding normal brain. This excellent tumor control prevents neurological death and maintains good activity of daily life. Although surgery with whole-brain radiation therapy (WBRT) remains an important option for patients with a solitary brain metastasis, SRS with or without WBRT should be considered in patients with a limited number of small tumors and a good prognosis. Many reports, as well as both retrospective and prospective reviews, have shown WBRT before or after SRS to improve local control and reduce new distant lesion emergence. However, upfront WBRT does not improve survival. There are two major delivery ...
The primary objective of this project is to investigate the effects of global change on the biodiversity of aphid communities in Western Europe. Biodiversity has been examined at 3 levels: total number of species, phenology and reproductive strategy. Data were provided by EXAMINE, the European suction traps network which has been now operating for 35 years. 392 different species have been identified. At each location, total number of species has been regularly increasing, one additional species being caught every 1 or 2 years depending on location. This is due to introduced species but also to warming which favours rare species. No general trend of increasing density has been detected, but phenological earliness of almost all species (annual date of first appearance in suction traps) is strongly correlated with temperature and especially with mean daily temperature (during more or less long periods of time lying principally in February and ...
This study was a retrospective evaluation of the efficacy of stereotactic radiosurgery (SRS) in patients with >4 metastases to the brain. Materials and Methods: Between January 2004 and December 2006, 68 patients with ?4 multiple brain metastases were included and reviewed retrospectively. Twenty-nine patients received SRS and 39 patients received whole brain radiotherapy (WBRT). Patients with small cell lung cancers and melanomas were excluded. The primary lesions were non-small cell lung cancer (69.0%) and breast cancer (13.8%) in the SRS group and non-small cell lung cancer (64.1%), breast cancer (15.4%), colorectal cancer (12.8%), esophageal cancer (5.1%) in the WBRT group. SRS involved gamma-knife radiosurgery and delivered 10?20 Gy (median, 16 Gy) in a single fraction with a 50% marginal dose. WBRT was delivered daily in 3 Gy fractions, for a total of 30 Gy. After completion of treatment, a follow-up brain MRI or a contrast-enhanced ...
BACKGROUND: Denys-Drash Syndrome (DDS) is an uncommon disorder that appears sporadically and in rare cases may be inherited as an autosomal dominant trait It manifests either at birth or within the first year of life and typically consists of the triad of congenital nephropathy, Wilms tumour and intersex disorder. CASE REPORT: A 10 year-old Caucasian girl was referred to the Dental Department, at Glasgow Royal Hospital for Sick Children by her Paediatric Nephrologist Consultant. The patient was being teased by her peers over her markedly discoloured teeth. The dental history revealed that the patient was a regular dental attendee from an early age. She was dentally anxious having only experienced dental treatment under general anaesthesia (GA) when she was 4 years old. Apparently her primary dentition also showed a generalised discolouration. TREATMENT: This consisted of multiple visits for diet analysis and tooth brushing instruction with the use of disclosing ...
BackgroundCharacterizing and comparing the determinant of cotinine concentrations in different populations should facilitate a better understanding of smoking patterns and addiction....Full Text Available
Questionnaires and twice daily peak expiratory flow measurements were used to evaluate the effects of the menstrual cycle in asthmatic women. Forty per cent of women reported premenstrual deterioration...Full Text Available
Because the proportion of Hispanic patients is increasing rapidly, most physicians are now coming into daily contact with Hispanics. In addition to obvious difficulty with oral communication, Hispanics...Full Text Available
Nov 5, 2010 ... PEM. The Particle Environment Monitor measures the type, amount, energy, ... info, Daily PEM HEPS and MEPS data at the original sensor ...
brain Printer-friendly version Email this page to a friend Share Primary lymphoma of the brain is cancer of the lymph cells that starts in the brain. Causes The cause of primary...
ObjectiveTo evaluate the primary care communications initiative, which introduced NHSnet to primary care in Scotland.DesignSemi-structured telephone...Full Text Available
Solid fuels such as coal, wood, and crop straw supply some fraction of household cooking and heating fuel for more than one billion people in China. As these fuels do not generally combust cleanly in household stoves, their use levies large health and environmental burdens, particularly in rural regions. Production of clean-burning fuels from agricultural residue offers one prospect for mitigating health and social burdens imposed by household use of solid fuels. This dissertation explores the question: how might production of clean-burning household fuels from agricultural residues affect human health and social conditions in rural China? I approach this question from three perspectives. First, a technically plausible but currently unproven village-scale energy technology is explored in a scenario bounded by natural resources and substantiated by engineering specifications, estimates of indoor exposures to air pollution, and epidemiological analyses. This analysis asks at the national ...
Purpose: To assess the prognostic value of biologic (p53, Ki-67) and clinical factors in squamous cell carcinoma of the oropharynx after radical surgery and postoperative radiotherapy (RT). Methods and Materials: Between 1985 and 1995, a total of 102 patients with 104 tumor sites were entered onto the study. Fifty-five primary tumors (53%) involved the tonsils, 26 (25%) the soft palate, and 23 (22%) the base of the tongue. Median age was 53 years (range 36-80 years). The clinical T- and N-categories (UICC 1997) were: T1 (30), T2 (47), T3 (22), T4 (5), N0 (33), N1 (28), N2 (42), and N3 (1). Histologically-clear margins were achieved in all patients by initial surgery. Postoperative RT to the primary and regional lymphatics was given, to a total of 60 Gy in 6 weeks, and single daily fractions of 2 Gy. The expression of the nuclear p53- and Ki-67-labeling index (LI) was investigated by immunostaining using the monoclonal ...
Objectives: Evaluate the effect of diet, physical exercise, and a daily oral intake of a soy isoflavones extract (Fisiogen) contained 200mg of Glycine max, which corresponded to 80mg of isoflavone (60.8mg of genistein, 16mg of daidzein and 3.2mg of glicitein) on leptin and other adipokines plasma levels in healthy obese postmenopausal women. Methods: A multicentric randomized longitudinal prospective cohort study was conducted in a sample of 87 healthy obese postmenopausal women. Patients were randomly assigned to a 1200kcal diet and exercise group (control group) or a group of 1200kcal diet, exercise, and daily oral intake of daily oral intake of a soy isoflavones extract (Fisiogen) contained 200mg of Glycine max, which corresponded to 80mg of isoflavone (60.8mg of genistein, 16mg of daid...
Ba, Cd, Cr, Cu, Fe, Ni, Pb and Zn were determined in birch leaves (Folium Betulae), dandelion roots (Radix Taraxacae), hawthorn blossom (Inflorescentia Crataegi) and their infusions by graphite furnace atomic absorption spectrometry (GFAAS) after microwave digestion of plant samples. Infusions were made from herbs according to prescription for patients, provided by the producer of medicine on the package. The results obtained were compared with daily requirements for each element. Results show high content of cadmium in the medicinal plants analyzed. The highest level in infusions was observed for Ni and Zn (over 90% of the total element concentration for Ni and in most cases over 50% for Zn), and the lowest for Cd and Pb. The calculated daily intake of majority of the analyzed elements was very low (under 1% of daily requirements)
This study focuses on comparing reports of nicotine withdrawal, craving, and depressive symptoms obtained using an Interactive Voice Response (IVR) system and several questionnaires. As part of a smoking cessation trial, daily reports of withdrawal, craving, and negative mood were collected using an IVR system for 7 days after participants attempted to quit smoking, and several pencil and paper questionnaires (i.e., the Minnesota Nicotine Withdrawal Scale, the Questionnaire on Smoking Urges, and the Center for Epidemiological Studies-Depression) were completed a week after the target quit date. The sample was composed of 378 daily smokers. Moderate to high correlations were found between the research questionnaires obtained at the end of the week and the corresponding daily IVR reports of ...
BackgroundFinasteride, a 5 alpha reductase inhibitor, is an established treatment for benign prostatic hyperplasia. The recommended dosage is 5 mg a day, however case reports have...Full Text Available
Asymptomatic alanine aminotransferase (ALT) elevations have been detected with acetaminophen use at the maximum daily dose of 4 grams/day (g/d) for more than 3 consecutive days in subjects with...Full Text Available
The Meteorological Service of Canada has made weather datasets available in real-time on the Internet, for use by those with an interest in solar applications. Ensemble weather models can be used to produce medium range forecasts of weather events and to predict the likely available kilowatt-hours (kWhrs) of solar energy. As such, solar sites can maximize their harvest and use of solar energy. This presentation highlighted several different types of renewable energy forecasts obtained from weather models, including forecasts of expected kWhrs from solar panels and wind turbines, daily forecasts of expected solar heated water volumes and forecasts of water collection potential from impending precipitation events. The value of renewable energy forecasts in helping the solar energy sector monitor daily energy loads as well as daily and weekly solar energy supply was emphasized. It was suggested that renewable energy forecasts ...
PurposeAuto-propagation of anatomical region-of-interests (ROIs) from the planning CT to daily CT is an essential step in image-guided adaptive radiotherapy. The...Full Text Available
1. The LD50 of iodomethane orally administered to rats is 76mg./kg. body wt. but repeated daily doses of 30–50mg./kg. body wt. are without effect. 2. Oral doses of iodomethane to...Full Text Available
A Staphylococcus strain was inoculated on the top and cut surfaces of freshly baked Southern custard pies which were then packaged in a pasteboard carton and held at 30 C. Daily plate...Full Text Available
Available in vitro and animal studies have shown cancer protective effects of tea polyphenols. Recent study suggests a greater protective effect of green tea intake on breast cancer...Full Text Available
A publication on Norwegian gas and gas export. The content is wide spread from use of gas in daily life via sub sea pipeline repair systems to an overview over tomorrows gas fields. (AG)
Objective: To investigate the efficacy, safety, and clinical benefit of a once-daily formulation of trazodone (Trazodone Contramid® OAD) in the treatment of major depressive...Full Text Available
... were given daily i.p. injections of either sesame oil (2.5 ml/kg, vehicle control) or VCD dissolved in sesame oil (80 mg/kg, 0.57 mmol/kg) for ... ...
Several drugs are available for the management of postmenopausal osteoporosis. This may, in daily practice, confuse the clinician. This manuscript offers an evidence-based update of previous treatment...Full Text Available
To make the doubly labelled water method for determining energy expenditure more applicable in a free-living population, collection of a single daily urine or breath sample would have advantages compared to a 24-hr urine collection. Coward et al. reported the use of a single daily urine sample. In the previously described study, a single urine collection and a fasting morning breath sample were collected from four men during two 21-day periods (fall, F, spring, S) while maintaining their body wts. on controlled diets (20% calories from protein, 40% from fat, 60% from CHO [F]; 20% protein, 20% fat, 60% CHO [S]). Urine and breath samples were analyzed to determine disappearance rates of D and "1"8O for up to 21 days. Values were compared with metabolizable energy intake levels (EI), with or without corrections for estimated changes in body composition assessed by several methods. Preliminary evaluations suggest that the single ...
Choice procedures have indicated that the relative reinforcing effectiveness of opioid drugs increases during opioid withdrawal. The demand curve, an absolute measure of reinforcer value, has not been...Full Text Available
Molecular life science is one of the fastest-growing fields of scientific and technical innovation, and biotechnology has profound effects on many aspects of daily life—often with deep, ethical...Full Text Available
Cimetidine 1 g daily is often continued for a fixed period beyond the time of healing of duodenal ulcer on the assumption that it might reduce the subsequent relapse rate. To test this, 194 patients...Full Text Available
BackgroundThere is need for a cognitive test battery that can be easily used in clinical practice to detect or monitor cognitive performance in patients with multiple sclerosis (MS)....Full Text Available
Premature circuit clotting is a major problem in daily practice of continuous renal replacement therapy (CRRT), increasing blood loss, workload, and costs. Early clotting is related to bioincompatibility,...Full Text Available
Diel variations in rates of C export, sucrose-phosphate synthase (SPS) and sucrose synthase (SS) activity, and C reserves were investigated in Zostera marina L. (eelgrass) to elucidate the environmental...Full Text Available
Summary Purpose BMS-275183 is an oral C-4 methyl carbonate analogue of paclitaxel that has the same mechanism of action, stabilization of tubulin polymerization. The present study was designed to: (i) assess the safety and tolerability of BMS-275183, and (ii) determine a suitable Phase II dose of BMS-275183 when given on a continuous daily schedule to patients with advanced solid tumor(s). Methods This was a multi-institutional, open-label, Phase I, single-arm dose escalation study in which cohorts of eligible patients with advanced malignancies were treated with BMS-275183 orally on a continuous daily schedule. The starting dose level was 6?mg/m2/day administered once daily. Cohorts of 3 patients were treated at each dose level provided no dose-limiting toxicities (DLTs) were observed. Ea...
Selective phosphodiesterase type 5 inhibitors (PDE5Is) have revolutionized the treatment of erectile dysfunction (ED) in men. As an on-demand treatment, PDE5Is have excellent efficacy and safety in...Full Text Available
Results of monitoring milk and tap water in New York City are presented. The New York City sample is a monthly composite of pasteurized milk purchased daily at retail stores. The monthly "9"0Sr to calcium ratios for New York City since the inception of the sampling program in 1954 are presented. Samples of New York City tap water are taken daily, so that by the end of the month, approximately 100 liters have been collected. The available cesium-137 data expressed as the "1"3"7Cs to "9"0Sr ratio are also given.
Non-linear autoregressive Markov regime-switching models are intuitive. Time-series approaches for the modelling of electricity spot prices are frequently proposed. In this paper, such models are compared with an ordinary linear autoregressive model with regard to their forecast performances. The study is carried out using German daily spot-prices from the European Energy Exchange in Leipzig. Four non-linear models are used for the forecast study. The results of the study suggest that Markov regime-switching models provide better forecasts than linear models. (author)
Non-linear autoregressive Markov regime-switching models are intuitive. Time-series approaches for the modelling of electricity spot prices are frequently proposed. In this paper, such models are compared with an ordinary linear autoregressive model with regard to their forecast performances. The study is carried out using German daily spot-prices from the European Energy Exchange in Leipzig. Four non-linear models are used for the forecast study. The results of the study suggest that Markov regime-switching models provide better forecasts than linear models. (author)
Purpose Skilled placement of peripherally inserted central catheters (PICC) has a profound impact on patient well-being and costs of care. The use of ultrasound-guided methods and prescribed training for cannulation skills are evidence-based practice recommendations. The purpose of this study was to compare two methods of PICC instruction on the acquisition of applied skills. Methods Residents were randomly assigned to one of two groups (N?=?16/16) of this blind-rater study and were trained to perform ultrasound-guided PICC cannulation using either simulation or apprenticeship methods. All residents were assessed placing a PICC in applied clinical patient care. Results Residents who completed simulation training had significantly better transfer of skills to applied clinical practice than ...
The Tennessee Valley Authority (TVA), the Electric Power Research Institute (EPRI), and the Department of Energy-National Energy Technologies Laboratory (DOE-NETL) are evaluating and demonstrating integration of terrestrial carbon sequestration techniques at a coal-fired electric power plant through the use of Flue Gas Desulfurization (FGD) system gypsum as a soil amendment and mulch, and coal fly ash pond process water for periodic irrigation. From January to March 2002, the Project Team initiated the construction of a 40 ha Carbon Capture and Water Emissions Treatment System (CCWESTRS) near TVA's Paradise Fossil Plant on marginally reclaimed surface coal mine lands in Kentucky. The CCWESTRS is growing commercial grade trees and cover crops and is expected to sequester 1.5-2.0 MT/ha carbon per year over a 20-year period. The concept could be used to meet a portion of the timber industry's needs while simultaneously sequestering carbon in lands which would otherwise ...
BackgroundThis study focuses on the role of an Internet-based group for people who have an autoimmune liver disease, primary biliary cirrhosis. Primary biliary...Full Text Available
BackgroundDepression is a common illness, often treated in primary care. Many studies have reported undertreatment with antidepressants in primary care. Recently, some studies also...Full Text Available
Purpose/Objective. Daily Cone-beam computed tomography (CBCT) in room imaging is used to determine tumour shrinkage during a full radiotherapy (RT) course. In addition, relative interfractional tumour and lymph node motion is determined for each RT fraction. Material and methods. From November 2009 to March 2010, 20 consecutive lung cancer patients (14 NSCLC, 6 SCLC) were followed with daily CBCT during RT. The gross tumour volume for lung tumour (GTV-t) was visible in all daily CBCT scans and was delineated at the beginning, at the tenth and the 20th fraction, and at the end of treatment. Whenever visible, the gross tumour volume for lymph nodes (GTV-n) was also delineated. The GTV-t and GTV-n volumes were determined. All patients were setup according to an online bony anatomy match. Retrospectively, matching based on the internal target volume (ITV), the GTV-t or the GTV-n was performed. Results. In eight patients, we ...
the revealed stage of T Tauri star evolution, is only a mere shadow of its former self. Once primary accretion starts, one has the (poorly quantified) ...
Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease with major morbidity and mortality. Therapeutic management is difficult, due to lack of conclusive data and individual disease...Full Text Available
Description: Hurricane Hugo, which struck South Carolina in September of 1989, destroyed a significant proportion of the State's timber. Primary wood-products ...
Idiopathic achalasia is a primary esophageal motor disorder characterized by esophageal aperistalsis and abnormal lower esophageal sphincter (LES) relaxation in response to deglutition. It is a rare...Full Text Available
OBJECTIVE AND DESIGNThis study used qualitative and quantitative methods to examine the reasons primary care physicians and nurses offered for their inability to initiate guideline-concordant...Full Text Available
Selenium and iodine are trace elements that play an important role in health of man and animals. Concerning supply of both elements it is important to meet nutritional needs. According to discoveries selenium is a part of an active group of glutathione peroxidase enzyme. It prevents necrotic changes in liver, muscle dystrophy and has impact on growth. Extensive studies on content of selenium in plant and animal origin products were started in the beginning of the seventies in Western Europe (Frankenberger, et al., 1998). The aim of our work was to determine selenium and iodine content in total diets of Slovene military. Slovene military nutrition is based on its own nutritional standards, which determine 200 #mu#g of iodine and 50 #mu#g of selenium in daily diet (Rep. Slovenija Ministrstvo za Obrambo, 1994). To determine if the amounts of both elements meet the standards we have analysed 20 total daily diets from four different barracks within ...
The objective of this study was to determine the effects of partially substituting cottonseed cake with graded levels of baobab (Adansonia digitata L.) seed cake (BSC) on milk yield and quality in Guernsey cows. Sixteen cows in mid-lactation and in their third parity were allocated to diets containing 0% (control), 5%, 10%, and 15% BSC in a completely randomized design. Each cow was given a daily feed ration of 6?kg and a basal diet of soya bean stover ad libitum. There were no differences in daily feed intake (P?>?0.05), but basal intake differed among all treatment groups with cows on the control diet having the highest intake (30???0.34?kg/day). Mean daily milk yield differed (P?P?P?P?P?>?0.05). These results indicate that BSC can substitute soya bean cake in dairy diets, but milk produ...
New York City data indicate that seasonal and annual variations in dispersion-normalized air pollutant concentrations appear to accurately reflect changes in source emission patterns. The normalized concentrations make it possible to observe the impact of regulatory changes on ambient air quality without these impacts being obscured by meteorological fluctuations. It is found that numerical modeling techniques and regression analysis can be powerful tools for extracting information from large sets of air quality data. The use of differential, as opposed to absolute, pollutant concentration values will reduce artifact correlations caused by seasonal, weekly, or daily meteorological fluctuations and will permit more accurate estimation of the regression coefficients. This technique was successfully applied to a set of daily pollution measurements whose absolute concentrations were found not to yield a statistically significant fit by multiple ...
New York City data indicate that seasonal and annual variations in dispersion-normalized air pollutant concentrations appear to accurately reflect changes in source emission patterns. The normalized concentrations make it possible to observe the impact of regulatory changes on ambient air quality without these impacts being obscured by meteorological fluctuations. It is found that numerical modeling techniques and regression analysis can be powerful tools for extracting information from large sets of air quality data. The use of differential, as opposed to absolute, pollutant concentration values will reduce artifact correlations caused by seasonal, weekly, or daily meteorological fluctuations and will permit more accurate estimation of the regression coefficients. This technique was successfully applied to a set of daily pollution measurements whose absolute concentrations were found not to yield a statistically significant fit by multiple ...
Contents include: index for 1970-1980; January 1981 data -- alert periods, daily solar indices, solar flares, solar radio emission, coronal holes, inferred interplanetary magnetic field polarities, mean solar magnetic field, spacecraft observations, December 1980 data -- daily solar-activity centers, sudden ionospheric disturbances, spacecraft observations, solar radio emission, cosmic rays, geomagnetic indices, radio-propagation indices; late data -- solar radio emission November, December 1980, spacecraft observations November 1980, cosmic rays, Huancayo Oct 1980 -- climax, alert, Deep River Nov 1980.
Analysis of Sr-90 in milk and tap water has been conducted in New York City since 1954. The milk sample analyzed is a monthly composite of pasteurized milk purchased daily at retail stores. The monthly Sr-90 to calcium ratios for New York City since the inception of the sampling progam in 1954 through 1981 are tabulated. Samples of New York City tap water are taken daily so that by the end of the month, approximately 100 liters have been collected. Data on Sr-90 since the inception of the program are presented. The available Cs-137 data expressed as the Cs-137 to Sr-90 ratio are given. A graphical presentation of the New York City Sr-90 data is also shown.
Objectives To delineate the safety and tolerability profile of methylphenidate and atomoxetine in children and adolescents with attention deficit hyperactivity disorder (ADHD) monitored for more than 1?year. Design A cohort study analyzing data from the national ADHD register on patients from the Lombardy Region treated with MPH or atomoxetine. Participants A total of 229 children (median age 11?years, range 6?17), enrolled in 15 regional centers between June 2007 and May 2010. Results The prevalence rate of pharmacological treatment for ADHD was 0.23%, whereas the estimated ADHD prevalence in the population was 0.95%. In total, 73.8% of patients had been treated with atomoxetine (10?90?mg daily) or MPH (10?75?mg daily); 22% of patients also received an additional psychotropic drug. Of the...
Even if there have been efforts to validate remote-sensing-based energy balance models, which provide evapotranspiration (ET) maps over a large spatial scale, few studies have been conducted to validate their performance in Korea. In this study, surface energy balance fluxes including ET were estimated and inter-compared with two different models using the Landsat-5 Thematic Mapper (TM) image over a watershed scale in Korea. While there were larger spatial discrepancies for net radiation, soil heat and sensible heat fluxes on a pixel-by-pixel basis between the two models, relatively smaller spatial discrepancies for the latent heat flux and daily ET were detected. The spatial discrepancies for the daily ET were larger in low topography and dense vegetation ranges. Despite the different par...
The biological half-life of "1"3"7Cs in the total body of human subjects was determined in 23 individuals of Japanese male adult in their normal works by measuring amount of "1"3"7Cs in both their total body and daily urine in the same period. For the group, the value was determined by averaging the half-lives for individuals, by comparing the mean body burden and the mean daily urinary excretion, or by applying a curve fitting method to the body burden estimate. The biological half-life averaged 86 days, ranging from 50 to 161 days. The averages of the biological half-lives for the group were 83, 87 and 82 days in the different periods of observation. By the curve fitting method, 85 days was found for the group. The biological half-life for the individuals depended on both body weight and age, to a lesser extent, of the subjects. (author).
Evidence for dietary/nutritional treatments of attention-deficit/hyperactivity disorder (ADHD) varies widely, from double-blind, placebo-controlled trials to anecdotal. In guiding patients, clinicians can apply the SECS versus RUDE rule: treatments that are Safe, Easy, Cheap, and Sensible (SECS) require less evidence than those that are Risky, Unrealistic, Difficult, or Expensive (RUDE). Two nutritional treatments appear worth general consideration: Recommended Daily Allowance/Reference Daily Intake multivitamin/mineral supplements as a pediatric health intervention not specific to ADHD and essential fatty acids, especially a mix of eicosapentaenoic acid, docosahexaenoic acid, and ?-linolenic acid as an ADHD-specific intervention. Controlled studies support the elimination of artificial fo...
Purpose Nonpoint sources (NPS) pollution has been an important cause for water quality impairment worldwide. To take the temporal variations of both NPS pollution and in-stream attenuation into consideration, an inverse modeling approach and the load duration curve (LDC) method were combined for variable nutrient total maximum daily load (TMDL) development. Methods Water quality and hydrological parameters were monitored monthly along the ChangLe River system in 2004?2008. The catchment NPS export load (EL) and TMDL for total nitrogen (TN) were estimated by the inverse format of an existing stream nutrient transport equation. The LDC method was used to describe the variability of EL, TMDL, requiring load (RLR) and percent (the ratio between the RLR and the EL, RPR) reduction, and then to s...
The bands may be classified as primary if they merge into the eyewall encircling the eye of the storm, or secondary if they are disconnected from the ...
This paper dealt with the identification of possible damaging mechanism of the collector of the WWER 440 steam generator, cracking of primary collectors, corrosion damage of the protective coat of the primary collector circumferential weld, cracking of breathing space in the region of blinding effect by corrosion and strain, leaking of disassembling joint of the primary collector lid and with the integrity of heat exchanging tubes.
An electric power generating apparatus is described, including: a solar collector; a primary thermal loop including primary thermal fluid; a cavity receiver to receive reflected solar energy from the solar reflector, convert the solar energy into thermal energy, and transmit the thermal energy to the primary thermal fluid by heating the primary thermal fluid not to exceed a given temperature, the given temperature being substantially equal to 700 F; a Stirling engine receiving the primary thermal fluid heated by the cavity receiver, including means to generate mechanical power and means to generate electrical power from the means to generate mechanical power.
Gadolinium (Gd) based contrast agents (GBCAs) in magnetic resonance imaging (MRI) are used in daily clinical practice and appear safe in most patients; however, nephrogenic systemic fibrosis...Full Text Available
The effective half-life based on urine bioassay results of Wolsung NPP's worker was calculated. The effective half-life for tritiated water vapour obtained was 5 {approx} 9 days. In comparison to 10 days reported for ICRP-30, it is lower than the corresponding half-life for Reference Man. Also, the half-life was calculated based on intake amount of daily water. According to this result, the metabolism was reviewed.
Crop water demand in the Okanagan Basin was determined for 1961 to 1990, 2010 to 2039, 2040 to 2069, and 2070 to 2099. Daily station temperature data were spatially interpolated to a 1 x 1 km grid and adjusted for elevation. Daily precipitation data were estimated across four climatic regions. Output from three global climate models (GCM), CGCM2, CSIROMk2 and HadCM3 was used to create future daily climate. Daily potential evapo-transpiration (grass reference) was estimated from an empirical relationship between Bellani-plate atmometer readings, temperature and extra-terrestrial solar radiation, and then modified by crop coefficients for all crops except pasture. Depending on GCM, projected water demand increased by 12-20% (2010 to 2039), 24-38% (2040 to 2069) and 40-61% (2070 to 2099). Possible elevated CO{sub 2} effects on stomatal conductance which may reduce water demand were not accounted for. ...
Daily exposures of adult beagle dogs to inhaled radon daughters plus uranium ore dust, with and without concurrent cigarette smoking, for 2 to 5-1/2 yr have produced massive pulmonary fibrosis and severe emphysema. The cumulative exposure doses are similar to those associated with a 5-fold or greater increase in death rate of uranium miners due to chronic respiratory insufficiency, including pneumoconiosis, pulmonary fibrosis, and emphysema.
Assisted users with expired passwords Closed 233 NCICB Support Wizard Accounts Tickets Set up Resource Accounts for individual developers to control and track access on QA Application servers Maintained daily account synchronization between GForge project developers and CVS write access accounts Created FTP and SFTP user accounts for TCGA test, analysis datasets downloads and analysis datasets management.
In the present study 12 diets, each one consisting of a pool of seven day diets, composed by four meals: breakfast, lunch, dinner and snack, adequate in energy and macro nutrients according to the RDA (Recommended Daily Allowance) recommendations, were elaborated and offered to a group of 12 men (19-42 years). The diets were collected by duplicate portion technique and dried by two different processes: freeze drying and 60 deg C ventilated oven drying. In the total, 24 diets were analyzed. The content of some minerals and trace elements (Ca, Fe, Mg, Mn, Na, Se and Zn) were determined by Instrumental Neutron Activation Analysis. The validation of methodology was made by analysis of the reference materials Typical Diet (NIST SRM 1548"a), Orchard Leaves (NIST SRM 1541) and Peach Leaves (NIST SRM 1547). The results observed by two different drying processes used were statistically compared by test T of Student. It was possible to conclude that the concentration means ...
The levels of four different heavy metals [cadmium (Cd), lead (Pb), chromium (Cr) and copper (Cu)] were determined in various vegetables [leek (Allium ampeloprasum), sweet basil (Ocimum basilicum), parsley (Petroselium cripsum), gardem cress (lepidium sativum) and tarragon (Artemisia dracuncullus)] cultivated around the Sanandaj city. (Author)
The levels of four different heavy metals [cadmium (Cd), lead (Pb), chromium (Cr) and copper (Cu)] were determined in various vegetables [leek (Allium ampeloprasum), sweet basil (Ocimum basilicum), parsley (Petroselium cripsum), gardem cress (lepidium sativum) and tarragon (Artemisia dracuncullus)] cultivated around the Sanandaj city. (Author)
Rice, the world's major staple crop, is a poor source of essential micronutrients, including folates (vitamin B9). We report folate biofortification of rice seeds achieved by overexpressing two Arabidopsis thaliana genes of the pterin and para-aminobenzoate branches of the folate biosynthetic pathway from a single locus. We obtained a maximal enhancement as high as 100 times above wild type, with 100 g of polished raw grains containing up to four times the adult daily folate requirement.
Daily oral treatment with the cyclopentyl 2′-deoxyguanosine nucleoside BMS-200475 at doses ranging from 0.02 to 0.5 mg/kg of body weight for 1 to 3 months effectively reduced the level of woodchuck...Full Text Available
...Box Contains One Month Supply Dietary supplement with a premium patented formula of L-Arginine, Ginseng, Ginkgo plus 13 essential vitamins, antioxidants, and minerals to support male sexual function . ArginMax for Male Sexual Fitness is a patented combination of l-Arginine, Ginseng, Ginkgo, and 13 essential vitamins and ...
Daily exposures of adult beagle dogs to inhaled radon daughters and to uranium ore dust for 4-1/2 to 6 yr have produced respiratory tract carcinomas, at similar cumulative working level months (WLM) of exposures to those which induced carcinomas in uranium miners. Biological data from the beagle-dog experiments can therefore be used for prediction of carcinogenic risk under changing exposure conditions in future uranium miners.
After baseline studies, 21 patients with osteoporosis were treated with human parathyroid hormone fragment (PTH 1-34) given as once-daily subcutaneous injections for 6-24 months. The dose used did not...Full Text Available
The Bavarian Agency for Environmental Protection (LfU) is monitoring the air quality is several bavarian regions. The daily and monthly data of concentration ration of sulfur dioxide, nitrogen oxides, carbon monoxide, ozone and other pollutants are published in yearly reports, most often as diagrams with further statistica information.
The study was conducted to determine potential target organ toxicity and its reversibility in hamsters following twice daily oral doses of NSC-D629243 for 28 consecutive days. Male and female hamsters were administered NSC-D629243 dissolved in sesame oil ...
We investigate opportunistic cooperation between unlicensed secondary users and legacy primary users in a cognitive radio network. Specifically, we consider a model of a cognitive network where a secondary user can cooperatively transmit with the primary user in order to improve the latter's effective transmission rate. In return, the secondary user gets more opportunities for transmitting its own data when the primary user is idle. This kind of interaction between the primary and secondary users is different from the traditional dynamic spectrum access model in which the secondary users try to avoid interfering with the primary users while seeking transmission opportunities on vacant primary channels. In our model, the secondary users need to balance the desire to cooperate more (to create more transmission opportunities) with the need for maintaining ...
Most breast cancers are multicentric in origin. They drain into two primary lymphatic depots—the axilla and internal mammary chain of nodes. The incidence of metastasis to the internal mammary...Full Text Available
BackgroundNew Zealand's Primary Health Care Strategy (NZPHCS) was introduced in 2002. Its features are substantial increases in government funding delivered as capitation payments,...Full Text Available
Primary peritoneal pregnancy has been reported and debated for almost a century. Case reports using Studdiford's criteria and later modified criteria have substantiated the entity, but the pathogenesis...Full Text Available
A series of 53 cases of primary hemifacial spasm have been evaluated by means of blink reflexes and their results compared with a normal control group. Reflex responses were obtained by percutaneous...Full Text Available
IntroductionWe report an unusual presentation of primary biliary cirrhosis.Case presentationWe present the case of a 66-year-old white British woman...Full Text Available
Background:Despite variations in technique, the results of primary and revision lumbar discectomy have been good. The aim of this study was to retrospectively review cases...Full Text Available
The objective of this study was to evaluate the effect of pregabalin in painful cervical or lumbosacral radiculopathy treated in Primary Care settings under routine clinical practice. An observational,...Full Text Available
The installation procedure, the fabrication, fitting up, positioning, adjustment and welding of piping, examinations, hydrostatics testing and insulation of piping for reactor primary circuit piping of Daya Bay Nuclear power Plant are briefly described.
An organ-specific invertase deficiency affecting only the primary root system is described in the Oh 43 inbred maize (Zea mays). Invertases (acid and neutral/soluble and insoluble)...Full Text Available
OBJECTIVE: To examine primary care physicians' management of rheumatoid arthritis, ascertain the determinants of management and compare management with that recommended by a current practice panel....Full Text Available
Sixty glaucomatous eyes of 60 patients treated with laser trabeculoplasty as primary therapy were reviewed retrospectively. There were 42 eyes with capsular glaucoma and 18 with simple glaucoma. The...Full Text Available
BackgroundIn primary hyperparathyroidism (PHPT) the predictive value of technetium 99m sestamibi single emission computed tomography (Tc99m-MIBI-SPECT) for localizing pathological...Full Text Available
BackgroundThe Government has invested £7 million (approx. $11.5 million) to connect all Primary Care Practices in Scotland to the National Health Service...Full Text Available
For many years, epidemiological studies have demonstrated a strong link between chronic hepatitis B virus (HBV) infection and the development of primary hepatocellular carcinoma (PHC). Other hepatocarcinogens...Full Text Available
The sensitive explosives used in initiating devices like primers and detonators are called primary explosives. Successful detonations of secondary explosives are accomplished by suitable sources of...Full Text Available
The glycolipid content of human non-seminomatous germ cell tumour cell lines correlates with their differentiation lineage. To analyse whether this reflects the situation in primary tumours, we studied...Full Text Available
Purpose:The risks and benefits of continuing bisphosphonate therapy beyond 5 years in patients with primary osteoporosis have not been well established.Methods:We...Full Text Available
Objective: The aim of this study was to characterize using flow cytometry cultured human primary keratinocytes isolated from the epidermis and hair follicles by different methods. Methods:...Full Text Available
PURPOSE We wanted to assess computer capabilities in a primary care practice-based research network and to understand how receptive the practices were to new ideas for automation of practice...Full Text Available
Nitrate reduction was studied as a function of carbohydrate concentration in detached primary leaves of barley (Hordeum vulgare L. cv Numar) seedlings under aerobic conditions in light...Full Text Available
BackgroundWe examined whether older adults who had continuity of care with a primary care physician (PCP) had lower mortality.MethodsSecondary analyses...Full Text Available
BackgroundPrimary hepatocytes are the best resource for in vitro studies directed at understanding hepatic processes at the cellular and molecular levels, necessary...Full Text Available
BackgroundUntil now only limited research has been done on the prevalence of chronic pain in primary care. The aim of this investigation was to study the health care utilisation...Full Text Available
PurposeTo analyze the contributions of cytochrome P4501B1 (CYP1B1) mutations to primary congenital glaucoma (PCG) in Spanish patients.MethodsWe...Full Text Available
Context: Mild primary hyperparathyroidism (PHPT) is characterized by asymptomatic hypercalcemia, most commonly in the absence of classical signs and symptoms. Hence, there is need to characterize...Full Text Available
ObjectiveTo estimate the joint effect of a multifaceted access intervention on primary care physician (PCP) productivity in a large, integrated prepaid group practice.Data...Full Text Available
This study examines the longitudinal relationship between personal and sexual partner incarceration and subsequent HIV risk behaviors among drug-involved men and their primary female sexual...Full Text Available
Secondary deuterium in the atmosphere are produced in interactions by primary cosmic rays. The shape of their energy spectrum depends on the primary cosmic ray spectrum incident at the top of the atmosphere. At high energies, the spectral shape depends on the primary spectrum of helium and heavy nuclei. However, at very low energies, specially below the geomagnetic cut-off, the spectral shape depends on the evaporation and recoil processes and hence almost independent of the spectral shape of the primary radiation. It is undertaken a calculation of the secondary deuterium spectrum at small atmospheric depths at various latitudes and the results will be presented.
... Title : Military Working Dog Procurements. ... Our primary objective was to determine whether recent procurements of military working dogs by the ...
The presentation deals with the flows on the primary side of a horizontal steam generator under conditions typical to natural circulation cooling of the reactor. The main goal is to analyse the effect of primary flow patterns on the heat transfer capability of the steam generator. Conclusions pertinent to steam generator modelling with system codes are also drawn. (10 refs., 9 figs., 4 tabs.).
The presentation deals with the flows on the primary side of a horizontal steam generator under conditions typical to natural circulation cooling of the reactor. The main goal is to analyse the effect of primary flow patterns on the heat transfer capability of the steam generator. Conclusions pertinent to steam generator modelling with system codes are also drawn. (10 refs., 9 figs., 4 tabs.).
The relative merits and difficulties of the primary and secondary origin hypotheses for the observed cosmic ray antiprotons, including the low energy measurement of Buffington, were examined. It is concluded that the cosmic ray antiproton data may be strong evidence for antimatter galaxies and baryon symmetric cosmology. The present antiproton data are consistent with a primary extragalactic component having antiproton/proton approximately equal to .0032 + or - 0.7.
The trade-off which must be established between the various functions of pumped-storage plants is examined. A compromise between supply security and economic planning can be found only by coordinated planning of pumped-storage units and thermal generation plants. A model used by Electricite de France (EDF) to ensure optimized daily planning of thermal and pumped-storage units is described. The model, called the DEMETER model, ensures the optimization of the daily planning of thermal and pumped-storage plants. The model iterates between two levels: coordination where the prices of the generated energy and the operating reserve are determined to adjust generation to load and keep a sufficient reserve; and decomposition where the schedule of each unit is optimized on the basis of the above prices and taking into account local constraints such as unavailability, and minimum shut down time. The role of EDF is to supply customers with energy while ...
This paper presents a Benders decomposition approach to determine the optimal day-ahead power scheduling in a pool-organized power system, taking into account dispatch, network and security constraints. The study model considers the daily market and the technical constraints resolution as two different and consecutive processes. The daily market is solved in a first stage subject to economical criteria exclusively and then, the constraints solution algorithm is applied to this initial dispatch through the redispatching method. The Benders partitioning algorithm is applied to this constraints solution process to obtain an optimal secure power scheduling. The constraints solution includes a full AC network and security model to incorporate voltages magnitudes as they are a critical factor in some real power systems. The algorithm determines the active power committed to each generator so as to minimize the energy redispatch cost subject to ...
Locomotive engineers (train drivers) on irregular work schedules reported a general coffee consumption rate higher than that reported by a comparison sample of permanent shift factory workers. The present study examines the impact of this consumption on workday and non-workday sleep behaviour and mood ratings. Twenty-seven engineers and their spouses each completed daily logs for 30 consecutive days. Daily logs were then sorted into workday and non-workday categories. Workday sleep length was significantly shorter than non-workday sleep length for both engineers and spouses. For the engineers only, coffee consumption on workdays was higher than on non-workdays. This increased coffee consumption was correlated with longer sleep latency, increased negative mood, and decreased positive mood on both work and non-workdays. This was not true for spouses. These results may be related to a days-off carry-over effect of caffeine or a general consumption ...
Two studies were conducted to investigate the effects of nutrition and suckling patterns on the ovarian cyclicity of postpartum buffaloes. In Study 1, which was conducted on an institutional farm, two different diets were fed to 24 buffaloes during late gestation and postpartum period. Restricted (twice daily) suckling began on day 30 postpartum in half the animals on each diet. The body weight of both ad libitum suckled and twice daily suckled groups declined during the postpartum period, irrespective of the diet fed. Buffaloes subjected to restricted suckling lost less body weight and re-established ovarian cyclicity earlier than those suckled ad libitum. In Study 2, which was conducted under village conditions, temporary calf removal for 72 hours on days 91-93 postpartum in anoestrous buffaloes induced the re-establishment of ovarian cyclicity within 14 days. (author). 11 refs, 7 tabs.
The use of primary electron counting techniques as an alternative to the more usual parallel plate avalanche chamber that has been employed in soft x-ray scattering experiments is being investigated at the National Synchrotron Light Source. The theoretical aspects of primary electron counting and motivation behind building a primary electron counting detector are described, as well as characteristics and future improvements of the device constructed at the NSLS. The detector consists of a low electric field drift region and a low pressure multistep avalanche region which can be operated with two or three stages of electron multiplication. The device has worked well in extensive tests as a simple parallel plate avalanche chamber, providing energy resolutions of 58% and 43% at 277 and 500 eV, respectively. Operated as a primary electron counter, preliminary results show an energy resolution of 38% at 500 ...
A detailed chemical kinetic reaction mechanism is developed for primary reference fuel mixtures of n-hexadecane and 2,2,4,4,6,8,8-heptamethyl nonane for diesel cetane ratings. The mechanisms are constructed using existing rules for reaction pathways and rate expressions developed previously for the primary reference fuels for gasoline octane ratings, n-heptane and iso-octane. These reaction mechanisms are validated by comparisons between computed and experimental results for shock tube ignition and for oxidation under jet-stirred reactor conditions. The combined kinetic reaction mechanism contains the submechanisms for the primary reference fuels for diesel cetane ratings and submechanisms for the primary reference fuels for gasoline octane ratings, all in one integrated large kinetic reac...
The Wind2H2 system is fully functional and continues to gather performance data. In this report, specifications of the Wind2H2 equipment (electrolyzers, compressor, hydrogen storage tanks, and the hydrogen fueled generator) are summarized. System operational experience and lessons learned are discussed. Valuable operational experience is shared through running, testing, daily operations, and troubleshooting the Wind2H2 system and equipment errors are being logged to help evaluate the reliability of the system.
The mammalian circadian timing system is organized into hierarchical structures with a central clock in the suprachiasmatic nucleus (SCN) and subsidiary peripheral oscillators. After the discovery of the local clockwork in peripheral organs and tissues, which have a molecular makeup similar to the central pacemaker SCN, uncovering the roles of the peripheral clock in the rhythmic physiology has been an emerging goal in chronobiology. Glucocorticoid (GC) is a multifunctional adrenal steroid hormone that shows a robust circadian rhythm. The daily GC rhythm has long been thought to be governed by the SCN via the hypothalamus-pituitary-adrenal neuroendocrine axis. Recent findings, however, indicate that multiple regulatory mechanisms, including the adrenal intrinsic mechanism by the peripheral...
This short article discusses the results of a market survey on ventilation systems for residential buildings and the role played by ventilation systems in our daily lives. Problems incurred as a result of insufficient ventilation conditions such as the formation of mould in dwellings whose windows have been replaced with better seals are discussed, for example. The negative image of air-conditioning and its causes are examined. The need for action in this area is stressed. Further findings of the study are presented, including a detailed review of current equipment and scenarios on how these systems can develop in the future. The extension of the study to cover the situation in further European countries is mentioned.
The effects of a timolol maleate gel-forming solution (TMGS) on intraocular pressure (IOP), blood pressure (BP), and pupil size (PS) were evaluated in normotensive dogs. TMGS was administered once daily to six normotensive beagle dogs. TMGS administration reduced IOP and PS. The hypotensive effect persisted for 24 hr after the administration. The mean reduction in IOP was 5.3 mm Hg (P<0.01). The changes in BP and PS were not significant. These results suggest that TMGS can potentially be used in the treatments of glaucoma and ocular hypertension in dogs. PMID:16820724
What makes teamwork tick?. Cooperation matters, in daily life and in complex applications. After all, many tasks need more than a single agent to be effectively performed. Therefore, teamwork rules!. Teams are social groups of agents dedicated to the fulfilment of particular persistent tasks. In modern multiagent environments, heterogeneous teams often consist of autonomous software agents, various types of robots and human beings. Teamwork in Multi-agent Systems: A Formal Approach explains teamwork rules in terms of agents' attitudes and their complex interplay. It provides the first comprehe
The solar powered electric vehicle race began in Arlington, Texas on June 20, 1993 and finished 7 days later in Minneapolis, Minnesota. Thirty four teams from Universities across the United States and Puerto Rico completed the race out of thirty six entries. The race demonstrated the viability of sunlight powered vehicles as the better average daily speeds were in excess of 50 miles an hour. Even in the rain, most average speeds were in excess of 15 miles an hour. Analyzed results, photographs, and project details are included. (GHH)
The objective of this work is a study for the application of a new technology that will be used in the engine management system in the vehicle; where the final consumer can opt for the inquiry performance or seeking an economy for the fuel consumption depending on its daily use and of the prices offered in the gas stations. Flexible Fuel is a technology in development for the automobile market that mixes the use of two fuels (gasoline and ethanol) and their mixtures in the internal combustion engine. (author)
We report a case of stress fracture of the clavicle associated with sternocostoclavicular hyperostosis. A 60-year-old man sustained a stress fracture of the right clavicle with no history of trauma. On radiography, hyperostosis of the anterior chest wall and ankylosis of the sternoclavicular joint were evident in addition to the fracture. Fracture healing was uneventful after 2.5 months. Ankylosis of the sternoclavicular joint may have caused increased stress at the midshaft of the clavicle by daily activity or minor trauma. Such a fracture is a rare complication of sternocostoclavicular hyperostosis. (orig.)
As the amount of urban and industrial wastes is increasing more and more, recycling is very necessary. Daily, there are many news about packing, even more since European Union is getting ready a Directive that will propose and will impose the reuse and recycling of the materials used to produce the packs. This Directive will be followed by different national laws of the countries members of EU. This paper describes the increasing use of aluminium for packing, and particularly its use for beverage cans, its characteristic and applications.
Control of human filarial infections currently depends on chemotherapeutic strategies predominantly directed at microfilariae. Doxycycline therapy in an extended daily dose regimen sterilizes and kills adult stages, but the utility of this drug for routine field use remains an issue of concern. No macrofilaricidal drugs with efficacy after one or two doses are available for use, delaying the achievement of the elimination or eradication of onchocerciasis and lymphatic filariasis. Moxidectin, a macrocyclic lactone, is currently in clinical trials for onchocerciasis. A few other drugs that have already been approved for use in veterinary practice or in human medicine for other indications are available for investigation. Early drug discovery pipelines are poorly populated and the process of ...
The Marine Technology Society 1994 conference was held in Washington, D.C., September 7-9, 1994. Titled Challenges and Opportunities in the Marine Environment, the conference offered a wide variety of presentations. State-of-the-art technology, government policies and regulations, and environmental concerns were addressed. Offshore mining, coastal zone management, marine engineering, oceanographic research, educational issues, and global climate change were also well represented in the presentations. The conference proceedings are organized around the daily sessions and roughly 70% of the papers are included.
This paper summarizes the investigation of horizontal direction drilling and the subsequent experimental installation of a natural gas network in a suburb of Paris, France. Three aspects of drilling were studied prior to implementation: (1) reliability of the technique and quality of pipelaying to ensure long-term supply main operation; (2) ability to assess the successfulness of the work by assessing preliminary conditions; and (3) economonic viability. Measurement of tensile stress on polyethylene pipe during pulling and comparative accelerated aging tests on scratched pipe were performed. In the implementation phase, 300 meters of pipe were laid daily, by using three machines simultaneously, at a cost comparable to that of conventional techniques.
With major D&D projects ongoing or being planned, and also with the daily management of radwaste from nuclear facilities, the potential role of transport packagings has often been overlooked: here will one rely essentially on drums, there several local waste processing units are built, elsewhere decommissioned facilities are cut in small bits to fit into small containers by far less efficient. The present paper proposes to illustrate how integrating a transport system from the start may influence operational choices of waste management.
Information security involves many branches of effort, including information assurance, host level security, physical security, and network security. Computer network security methods and implementations are given a top-down description to permit a medically focused audience to anchor this information to their daily practice. The depth of detail of network functionality and security measures, like that of the study of human anatomy, can be highly involved. Presented at the level of major gross anatomical systems, this paper will focus on network backbone implementation and perimeter defenses, then diagnostic tools, and finally the user practices (the human element). Physical security measures, though significant, have been defined as beyond the scope of this presentation.
SO/sub 2/ concentrations in the Stuttgart air have been measured continuously since 1965. The two measuring points were located at the bottom of the Stuttgart city basin and 900 m east on the side of one of the surrounding hills. Long-term curves of pollutant loads have been established in consideration of meteorological parameters, as well as curves showing the average daily, weekly, and yearly pollution. The information thus gained may help to plan air pollution abatement measures in city planning.
... Focuses on distillation and packed towers, and presents the methods and fundamentals of plant design along with supplemental mechanical and related data, nomographs, data charts and heuristics. AU$223.45 ex-GST Terms and Conditions CRC Handbook of Chemis... For almost a century this handbook has been updated annually, except for a few wartime years, and has served generations of engineers and scientists. Current daily price AU$209.09 ex-GST Terms and Conditions Perry's Chemical Engin... Was: $199.95 inc gst NOW: ...
In a PWR type reactor, a primary coolant circuit system using a steam generator is adopted in order to accelerate depressurization of a primary coolant circuit upon small rupture LOCA in which the pressure of the primary coolant circuit is moderately depressurized. A secondary coolant circuit depressurization valve is disposed to a main steam pipeline. The valve has a performance of automatically opening to remove heat by evaporation of water stored in SG for a short period of time when the pressure in the primary circuit is decreased to about 50kg/cm[sup 2] upon occurrence of LOCA or the like. Then, the secondary side of the SG is depressurized to about atmospheric pressure and gravitational water injection from a condensate tank is started. Further, a gas vent valve is disposed to a water chamber of the steam generator. The valve has a performance of automatically opening to discharge incondensible ...
To utilize solar energy effectively, a method has been developed by which daily clearness indexes can be estimated from phrase of general weather condition, and it has been examined at four places located at different typical climatic divisions in Japan. Successive results of extra-terrestrial solar insulation and measured solar insulation were illustrated at each place. It was found that the envelope of maximal value among measured values is in proportion to the extra-terrestrial solar insulation. Based on the basic clearness index and the meaning of term expressing general weather condition defined by the Meteorological Agency, the general weather condition was quantitated using the clearness index. This value was defined as weather index. Relationship between the measured clearness index at each place and the weather index was analyzed regressively. Correlation between the both was highly close, proportionally. Accordingly, the clearness index can be estimated ...
Purpose: To evaluate the significance of preoperative localization of abnormal parathyroid glands to the surgical outcome in patients with primary hyperparathyroidism. Material and Methods: Thirty-nine patients with primary hyperparathyroidism were studied preoperatively with US (39 patients), CT (30 patients) and MR imaging (18 patients). The overall diagnostic accuracy for US was 87%, CT 66% and MR 94%. In patients with a single parathyroid adenoma US was the most cost-effective localization technique with a detection rate of 96%. CT had a lower detection rate (78%) but was of particular value for fairly large ectopic adenomas in the root of the neck. MR imaging was a good confirmatory test (93%). In patients with multiple gland disease (primary hyperplasia and multiple adenomas), no single localization study alone was sufficient. Combination of all 3 studies, however, alerted the physician to the presence of disease in ...
The present work addresses an off-axis Cassegrain optical concentration system. The specific primary collector analyzed, a short focal length parabolic concentrator, is at the University of Florida`s Energy Park. A secondary hyperbolic reflective element was designed to redirect the solar radiation from the primary focal plane to an off-axis target on the polar axis of the primary concentrator. This ground level target will be required for planned experimental work. The analysis was performed using a numerical ray tracing procedure that incorporates both random and systematic errors due to slope and surface irregularities. The optimization process varied secondary element size, curvature, and offset angle, and yielded information required for optimum design. As a single secondary element was found impractical, three elements were designed for use at various time of the year. The numerical analysis predicts that typically 70 ...
This paper summarises the main results obtained so far in the frame of the EU Home Team test programme of ITER primary wall small scale mock ups. It describes briefly the fabrication method of the mock ups, the test conditions and the main results obtained with high heat flux and thermal fatigue tests of Cu alloy/stainless steel and beryllium/Cu alloy/stainless steel mock ups. The results obtained so far show good thermal fatigue performance and operation margin of the ITER primary first wall concept. (author)
we report an ultrafast synchrotron x-ray phase contrast imaging study of the primary breakup mechanism of a coaxial air-assisted water jet. We demonstrate that there exist great similarities in the phenomenology of primary breakup with that of the secondary breakup. Especially, a membrane-mediated breakup mechanism dominates the breakup process for a wide range of air speeds. This finding reveals the intrinsic connections of these two breakup regimes and has deep implications on the unified theoretical approach in treating the breakup mechanism of high speed liquid jet.
Abstract Prostate leiomyosarcoma is an extremely rare and highly aggressive neoplasm that accounts for less than 0.1% of primary prostate malignancies. Herein, we present a patient with primary leiomyosarcoma of the prostate with lung metastasis diagnosed primarily on fine-needle aspiration cytology. Characteristic cytological features such as small fascicles of spindle cells with blunt-ended nuclei, positivity for desmin and smooth muscle actin along with the radiological features are helpful in the correct diagnosis. Diagn. Cytopathol. 2010. 2010 Wiley-Liss, Inc.
Forty-three patients with basal and squamous cell carcinomata arising on the pinna were treated radically using a 10 MeV electron beam. The technique and dosage are described and discussed. Primary cancer control with retention of the pinna was achieved in 34 patients. Salvage pinnectomy was performed in four patients for recurrence and one patient for radiation necrosis. Two patients with large primary tumours failed to resolve and died of their disease. The advantages for the patient of the policy of primary radical electron beam therapy are discussed.
This paper presents the main achievements of the European Home Team (EU HT) test programme of ITER primary wall small scale mock ups. It describes briefly the fabrication method of the mock ups, the test conditions and the main results obtained with high heat flux and thermal fatigue tests of Cu alloy/stainless steel and beryllium/Cu alloy/stainless steel mock ups. The results obtained so far show very good thermal fatigue performance and operation margin of the ITER primary first wall concept.
Patients rely on their primary care physician to manage multiple, often chronic medical conditions that require prescription medications. Balancing the risk to benefit of treatments can be challenging...Full Text Available
Although clinic environments are a primary location for exchanging information with clinicians, patients experience these spaces as harsh environments to access, use, exchange, and manage information....Full Text Available
The vomeronasal organ is the primary olfactory organ that detects sexual pheromones in mammals. We investigated the anatomy of the vomeronasal organ of the tammar wallaby (Macropus eugenii),...Full Text Available
The primary determinants of pulmonary disease are environmental. The same thinness and delicacy of the air-blood barrier which allows rapid exchange of oxygen and carbon dioxide also reduce its effectiveness...Full Text Available
A review is made of some recent developments in the application of the Bohr Hamiltonian to transitional nulcei. The primary concern is to understand the advantages and limitations inherent to the basic model and its many variants. (author).
Background The crucial role of cigarette smoking in the development of pneumothorax is unclear because nonsmokers can also develop primary spontaneous pneumothorax. The purpose of this study was to clarify the pathophysiologic effects of cigarette smoking and its clinical correlations in primary spontaneous pneumothorax. Methods Included were 115 specimens of lung tissue from patients with primary spontaneous pneumothorax who underwent video-assisted thoracoscopic surgery from January 2001 to December 2002. We reviewed the clinical features of 56 smokers and 59 nonsmokers with an average follow-up of 67 months. The pathologic findings of resected lung specimens were analyzed retrospectively. Results There were no statistical differences in sex, age, body height, body weight, body mass inde...
The forced nonlinear vibration and its stability of a single-degree-of-freedom system with a ball screw type damper which is composed of a ball screw, a flywheel and a flyball governor are discussed theoretically. The results are compared with a linear solution and the experimental results. The effect of vibration isolation of the damper is also discussed. Numerical examples are given for several ratios of the natural frequencies in the primary system to the governor. It is demonstrated that, when the natural frequency ratio is chosen suitably, the damper is effective in suppressing the resonance of the primary system. The amplitude response curve of the primary system is approximately equal to the linear solution except in the vicinities of the natural frequencies of the primary system and the governor, and is stable except in the vicinity of the natural frequency of the governor. (author).
The precautionary principle has provoked a spirited debate among environmentalists worldwide, but it is equally relevant to public health and shares much with primary prevention. Its central components...Full Text Available
BackgroundOptimal treatment of primary negative symptoms is important because their presence is associated with poor outcome.AimsTo systematically review all studies dealing with the efficacy of pharmacological agents on primary negative symptoms.MethodA comprehensive search of the relevant literature was undertaken using electronic database, reference lists and personal contact.ResultsThere is a lack of standardized research designs. Amisulpride is the most extensively studied drug with respect to efficacy against primary negative symptoms. At low doses it demonstrates a consistent, modest effect compared to placebo, though not to conventional antipsychotics and has yet to be tested against other atypicals. Evidence from multiple studies that used simple statistical analyses and inclusion...
... system size exhibit a stochastic decomposition property ... to manage congestion in the primary queue. ... video at individual computer network terminals. ...
Minimally invasive parathyroidectomy is the procedure of choice for primary hyperparathyroidism due to parathyroid adenoma. Localization of the offending adenoma in minimally invasive parathyroidectomy...Full Text Available
The MRI's of 16 patients with either primary or secondary lymphatic disorders are evluated and the findings are compared to those from lymphangioscintigraphy or surgery. (author).
Two-way communication between the conceptus and the mother during early pregnancy is essential if the pregnancy is to survive. In this review, our primary focus is on biochemical communication...Full Text Available
The fields in this dataset are: Date Lake Depth Dissolved Organic Carbon Dissolved carbohydrates and amino acids Inorganic Nutrient Concentrations Primary ...
Twenty-two patients with vertebral primaries were registered in the Intergroup Ewing's Sarcoma Study between 1973 and 1977. The radiation doses to the primary tumors ranged between 3800 and 6200 rad. All patients received intensive combination chemotherapy. After a followup ranging between 14 and 62 months, 14 patients remained disease-free. All patients with primary tumor of the cervical and dorsal spine remained disease-free. Of eight patients with lesions in the distal spine, (sacrococcygeal region) six developed recurrence, in three a local recurrence was observed despite doses of 6000 rad or higher. Doses of 5000 rad or less (in addition to combination chemotherapy as used in the Intergroup Ewing's Study) appear adequate in controlling the primary tumors of the proximal segments of the spinal column.
Primary cardiac angiosarcoma is a rare cardiac tumor. The initial clinical course is often asymptomatic, and metastatic disease is present in a majority of affected patients at diagnosis. We present...Full Text Available
The major degradation mechanisms acting during the aging of selected WWER-440/213 primary circuit facilities were assessed critically. The analysis gave evidence that such mechanisms include radiation and fatigue damage of the reactor pressure vessel (effect of the neutron flow, cyclic fatigue promoted by the corrosive medium, effect of thermal aging), corrosion-mechanical and thermo-mechanical (fatigue) damage of the steam generator (stress corrosion cracking, erosion corrosion, thermal aging, wear), thermal and dynamic aging of the pressurizer, and corrosion-mechanical damage of the primary circuit piping (thermal aging, corrosion). (J.B.). 5 tabs., 1 fig., 62 refs.
BackgroundGhana has not conducted a national tuberculin survey or tuberculosis prevalence survey since the establishment of the National Tuberculosis Control Programme. The primary...Full Text Available
OBJECTIVE: To evaluate the effectiveness of a program to improve hypertension control practices in primary care. DESIGN: Retrospective quasi-experimental study. SETTING: Three hospital-based family...Full Text Available
The paper presents a computer-aided analysis of the combined use of ventilation and structural heat capacity and insulation as a means of saving air-conditioning power in digital telephone exchanges. It is shown that such savings can be effected by increasing air change with outdoor cool air at night, and when feasible, also in daytime, through the air change unit, in a conventional airconditioning cycle. The total thermal time constant (TTTC) method of calculation used enables the evaluation of daily or seasonal heat-flow balance for a given indoor temperature, considering the tendency of the heat capacity of the building and of envelope components to flatten the fluctuations of this temperature.
Traffic characterization is an important means for Internet Service Providers (ISPs) to adapt and to optimize their networks to the requirements of the customers. Most network measurements are performed in the backbone of these ISPs, showing both, residential and business Internet traffic. However, the traffic characteristics of business and home users differ significantly. Therefore, we have performed measurements of home users at a broadband wireless access service provider in order to reflect only home user traffic characteristics. In this paper, we present the results of these measurements, showing daily traffic fluctuations, flow statistics as well as application distributions. The results show a difference to backbone traffic characteristics. Furthermore, we observed a shift from web...
The need for alternative energy increases steadily???especially due to the climate change and the limited availability of fossil fuels. Geothermal power uses the intrinsic heat which is stored in the accessible part of the Earth???s crust. Its importance among the renewable energy resources originates from the almost unlimited energy supply of the Earth and its independence from external influences such as seasonal or even daily climatic variability. Nevertheless, there are risks which have to be assessed. From a mathematical point of view there are four building blocks of the characterization of deep geothermal systems: seismic exploration, gravimetry, modeling transport processes, and modeling the stress field. In particular, local depletion poses a significant risk during the industrial...
Introduction: Intractable ascites in neonates has a varied etiology; and often, the cause is idiopathic. The management usually consists of observation, diuretics, paracentesis, albumin replacements, and self correction. However, in some cases, the above treatment remains unsuccessful. Results: We present 2 cases of intractable ascites causing metabolic abnormalities, severe protein and immunoglobulin loss, and respiratory compromise. Although the use of peritoneovenous shunts for intractable ascites has been reported previously, our cases differ in both technique and patient size. Our first patient is an ex-28-week premature, 1.4-kg infant with intractable ascites for which a peritoneal drain was initially placed. After 3 weeks and putting out nearly 300 mL of ascitic fluid daily, we plac...
Blood kinetics and tissue distribution of 20, 80 and 110 nm silver nanoparticles were investigated in rats up to 16 days after intravenous administration once daily for 5 consecutive days. Following both single and repeated injection, silver nanoparticles disappeared rapidly from the blood and distributed to all organs evaluated (liver, lungs, spleen, brain, heart, kidneys and testes) regardless of size. The 20 nm particles distributed mainly to liver, followed by kidneys and spleen, whereas the larger particles distributed mainly to spleen followed by liver and lung. In the other organs evaluated, no major differences between the sizes were observed. Size-dependent tissue distribution suggests size-dependent toxicity and health risks. Repeated administration resulted in accumulation in li...
A large database (507 station-years) of daily suspended particulate matter (SPM) concentration and discharge data from 36 stations on river basins ranging from 600?km2 to 600,000?km2 in size (USA and Europe) was collected to assess the effects of SPM transport regime on bias and imprecision of flux estimates when using infrequent surveys and the discharge-weighted mean concentration method. By extracting individual SPM concentrations and corresponding discharge values from the database, sampling frequencies from 12 to 200 per year were simulated using Monte Carlo techniques. The resulting estimates of yearly SPM fluxes were compared to reference fluxes derived from the complete database. For each station and given frequency, bias was measured by the median of relative errors between estima...
Unlike the conventional automotive, modem railway trains are designed with non-openable windows; and a mechanical ventilation and air-conditioning (MVAC) system is installed in each train compartment for better indoor air quality as well as to provide a thermally comfortable environment. The ventilation rate is no doubt a critical element in the design of a MVAC system, especially in Hong Kong where the daily passenger load is extremely heavy. Earlier studies illustrated that carbon dioxide can be controlled at 1000 ppm by increasing the ventilation rate to 25.2 m{sup 3} h{sup -1}; however, it will also lead to an increase in energy consumption. In this paper, the electrical energy consumption at various ventilation rates was studied, and the cost of maintaining a low carbon dioxide level was estimated These provide solid information for the local railway companies to improve the air quality inside the train compartments. (author)
The effects of oral administration of aqueous extract of Bulbine natalensis Baker stem at daily doses of 25, 50, and 100mg/kg body weight on the reproductive function of Wistar rats were evaluated. The indices of mating and fertility success as well as quantal frequency increased after 7 days of treatment in all the dose groups except the 100mg/kg body weight group. The number of litters was not statistically different (P>0.05) from the control. Whereas the absolute weights of the epididymis, seminal vesicle, and prostate were not affected, that of the testes was significantly increased. The epididymal sperm count, motility, morphology, and viscosity were not different from the control after 7 days of treatment. The male rat serum testosterone, progesterone, luteinizing hormone, and follic...
Individuals who use augmentative and alternative communication (AAC) depend on technology to meet their daily needs and form relationships. Speech generating devices (SGDs) are integral components of communication systems. Reliability of SGDs is critical for effective use in everyday life. This study examined the reliability of new SGDs and found that mean time to first failure was 42.7 (SD = 41.2) weeks and at least 40% required repairs within the first year of use. The components that most frequently broke down were touch screens, wiring, main boards, batteries, memory cards, and AC adaptors. The costs of repairing SGDs were analyzed. The clinical implications of device breakdown are identified for key stakeholders, including clients, families, service providers, funding agencies, and ma...
The effect of mean daily air temperature (MDT) on flowering rate (the reciprocal of days to flower) was quantified for 18 species of annual bedding plants. Plants were grown in environmental growth chambers at constant air temperature set points of 5, 7.5, 10, 15, 25, or 30^oC and under an irradiance of 160-180mmolm^-^2s^-^1, with a 16-h photoperiod. Nonlinear mathematical equations were developed to predict the effect of MDT on flowering rate and to estimate the base, optimum, and maximum temperatures (Tmin, Topt, and Tmax), which are the temperatures at which flowering rates are zero (low temperature), maximal, and zero once again (high temperature), respectively. The estimated Tmin varied among species and ranged from 1.1^oC in French marigold (Tagetes patula L.) to 9.9^oC in angelonia ...
ABSTRACT Aim The study aimed to test simultaneously our understanding of the effects of bupropion sustained-release (SR) treatment on putative mediators and our understanding of determinants of post-quit abstinence, including withdrawal distress, cigarette craving, positive affect and subjective reactions to cigarettes smoked during a lapse. The specificity of bupropion SR effects was also tested in exploratory analyses. Design Data from a randomized, placebo-controlled clinical trial of bupropion SR were submitted to mediation analyses. Setting Center for Tobacco Research and Intervention, Madison, WI, USA. Participants A total of 403 adult, daily smokers without contraindications to bupropion SR use. Intervention Participants were assigned randomly to receive a 9-week course of bupropion...
Although managing fisheries is complex, policymakers must make decisions daily that affect the future of aquatic resources. To make these decisions, they often combine a mental model with lessons learned from formal models such as computer models. While such computer models are frequently interpreted as predictors of the future, they are often more valuable when used as tools for learning about fisheries and options for management. This approach, looking at computer simulations as learning laboratories, is what this study is all about since its objective is to investigate by means of a microworld if policymakers in Belgian fisheries have the policy instruments at hand to align the real fisheries world with their often completely different desired fisheries worlds. This study illustrates ba...
The effects of exposure to sublethal levels of microwaves were studied. Young albino rats of both sexes were exposed for 60 days to 7.5-GHz microwaves (1.0-KHz square wave modulation, average power 0.6 mW/cm2) for 3 h daily. During and after microwave exposure several physiological parameters were measured in both control and exposed animals. It was found that the animals exposed to microwaves tended to eat and drink less and thus showed a smaller gain in body weight. Some of the hematological parameters and organ weights were also significantly different. It is proposed that a nonspecific stress response due to microwave exposure and mediated through the central nervous system is responsible for the observed physiological changes.
The treatment of chronic pain conditions continue to present a challenge to the medical field. Physical therapy treatment needs to approach the management of chronic pain differently than the approach used to resolve acute pain. Patients with chronic pain often have many factors that have perpetuated the pain condition. These factors, as well as pain itself, influence their ability to reactivate and perform functional daily activities. Physical therapists can begin to address some of the factors, including fear and deconditioning, by building confidence and body awareness in a self-care model including a slow graduated reactivation program. There is evidence that patients with chronic pain conditions have altered motor control that may be influencing reoccurrences and possible flares of pa...
Knee osteoarthritis (OA) is a common degenerative joint disorder and a major cause of pain and disability. The hypothesis tested in this study was that the passion fruit peel extract (PFP), a flavonoid-rich dietary supplement, would reduce symptoms due to knee OA. Thirty-three OA patients were enrolled in a randomized, double-blind, placebo-controlled trial with parallel-group design. Patients received either placebo or PFP pills (150 mg, daily) in a double-blinded fashion for 2 months. The OA clinical symptoms were evaluated monthly with Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index. In the PFP group, there was a significant improvement in total WOMAC score and WOMAC subscale score of physical function after 30 days and pain after 60 days. At 60 days, reductions o...
PURPOSE.- The study aims to clinically validate the defining characteristics (DCs) of the nursing diagnosis (ND) of Activity Intolerance for patients with ischemic heart disease and refractory angina. METHODS.- Cross-sectional study was used, involving 22 patients with ND of Activity Intolerance. The Fehring method was used to validate the ND. FINDINGS.- Most DCs presented reliability indexes between 0.5 and 0.79. Three DCs presented reliability indexes - 0.8. CONCLUSION.- All DCs were validated, and electrocardiographic changes indicating ischemia, verbal report of fatigue, and abnormal rate response to activity were considered as DC major. IMPLICATIONS FOR NURSING PRACTICE.- This study is relevant in daily nursing practice for guidance in establishing the care plan and describing the ass...
Accessible summary - -Children with a Nonverbal Learning Disability (NLD) resulting from shunted hydrocephalus and spina bifida face many difficulties not experienced by those with a language learning disability. - -As they grow older and more autonomy is expected, friendships became harder to sustain and daily life can be full of fear if the nonverbal learning disability is not identified and managed. - -This paper explains the theorised cause of nonverbal learning disability - damage to right hemisphere white matter or myelin. - -Damage is believed to cause problems with planning, organisation, time management, problem-solving, decision-making and friendships, and the mismatch with articulate speech and a good vocabulary causes a functional profile that is difficult for educationists or ...
This guide is intended to provide the necessary guidance to successfully manage the NAVMED Navy Occupational Health Information Management System (NOHIMS) at NAVMED sites and the NAVSEA Occupational Safety and Health Record Keeping System (OSHRKS) at NAVSEA sites. Outlines procedures to manage system operations, procedures to resolve hardware, software and communications problems, and procedures outside the realm of system operations that are required for a successful system. This guide is intended for the System and Functional Managers use. The System Manager is the individual designated to provide overall ADP management to the entire local configuration. Usually responsible for file backup, daily operations of the CPU, security, supplies, equipment, operating software and technical ADP guidance to the local functional users.
The consequences of exit, voice, loyalty, and neglect behavior were examined using retrospective questionnaires (Study 1) and 2 social interaction diary studies (Study 2). Exit and neglect were generally associated with more negative partner responses and reduced feelings of value and closeness, and were reported to be more harmful to the relationship. Voice was associated with more positive partner responses and greater value and intimacy, and was perceived to be most beneficial to the relationship. In contrast, loyalty was perceived to have the same detrimental consequences as destructive behaviors (Study 1) and did not predict more positive outcomes within daily interactions (Study 2). These results indicate that, despite good intentions, loyal intimates are often left feeling ignored a...
A female employee was exposed to lead dust for 8 h daily from 4.5.1982 to 20.5.1982. During this time conception occurred (1st day of last menses 4.5.82). Acute symptoms of lead intoxication were not observed in this subject but were in other employees. Measurements of lead content were started after the end of exposure and continued for 6 months until normal values were obtained. Because of the half-life of nearly 20 days for lead elimination from blood the estimated body burden at the end of exposure was about 1200 ppb. The fetal tissue samples contained between 0.4 (brain) and 7.9 (liver) ..mu..g lead/g dry weight. The fetal lead was mainly stored in bone, blood and liver. From the results given a delayed elimination of fetal lead is suggested.
Short-duration measurements have been widely used to screen for exposures to elevated radon concentrations in individual houses or at state or regional levels. However, a number of factors, including spatial and temporal variability in radon concentrations, must be considered before comparison to concentration guidelines can be made. Daily variations in radon concentration can lead to inherent measurement uncertainties ranging from 20 to 100+ percent. Differences in radon concentration due to seasonal effects and/or sampling location are also variable, and do not appear to be regionally consistent. Winter/summer concentration ratios, for example, have been observed to vary by as much as a factor of 10 in basements and by a factor of 5 in first floors. In this paper the implications of these uncertainties on the use of short-term sampling for inferring long-term exposures are discussed.
Tests on the scrubbing column have led to the following results: Use of a scrubbing column with Raschig rings is only meaningful for the sedimentation of particles exceeding diameters of 0.5 ..mu..m; drops of diameter size 1.5 ..mu..m are formed in the column; more efficient drop precipitators in the column air flow ease the load on subsequent suspended material filters thereby contributing to a longer life of these filters even at higher sodium ion concentrations in the washing water; with distillate of an 8% rather than 0.8% salt solution a decontamination factor greater than 10 can be calculated since larger particles precipitate more readily. This only applies, however, under the condition that the washing water is renewed regularly, if necessary daily where higher aerosol concentrations are present. If not, the decontamination factor will be reduced through the salt-containing secondary aerosols from the washing water.
Tests on the scrubbing column have led to the following results: Use of a scrubbing column with Raschig rings is only meaningful for the sedimentation of particles exceeding diameters of 0.5 #mu#m; drops of diameter size 1.5 #mu#m are formed in the column; more efficient drop precipitators in the column air flow ease the load on subsequent suspended material filters thereby contributing to a longer life of these filters even at higher sodium ion concentrations in the washing water; with distillate of an 8% rather than 0.8% salt solution a decontamination factor greater than 10 can be calculated since larger particles precipitate more readily. This only applies, however, under the condition that the washing water is renewed regularly, if necessary daily where higher aerosol concentrations are present. If not, the decontamination factor will be reduced through the salt-containing secondary aerosols from the washing water. (orig.).
We investigate the intertemporal risk-return trade-off of foreign exchange (FX) rates for ten currencies quoted against the USD. For each currency, we use three risk measures simultaneously that pertain to that currency; its realized volatility, its realized skewness, and its value-at-risk. We apply monthly FX excess returns and risk measures calculated from daily observations. We find that there is a significant contemporaneous risk-return trade-off for the currencies under investigation. There is no evidence of noncontemporaneous risk-return trade-off. We pay special attention to the risk-return trade-off during the recent financial crisis.
Pots used for experiments conducted on plants grown in them create rooting environments that are affected by limited soil volume, which can affect various physiological processes, including transpiration, and plant growth. However, the applicability of results from pot experiments to the field has received limited attention. The objective of this study was to compare the growth and transpiration of maize (Zea mays L.) and winter wheat (Triticum aestivum L.) when grown in pots and field plots under various constant water deficits. The experiments were conducted under similar environmental conditions for both pots and plots. Transpirational responses at both transient (RTTr) and daily (RDTr) time scales to a decreasing fraction of available soil water (FASW) were analyzed. For a comparable F...
Good performance in extended lactations of dairy cattle may have a beneficial effect on food costs, health, and fertility. Because data for extended lactation performance is scarce, lactation persistency has been suggested as a suitable selection criterion. Persistency phenotypes were calculated in several ways: P1 was yield relative to an approximate peak, P2 was the slope after peak production, and P3 was a measure derived to be phenotypically uncorrelated to yield and calculated as a function of linear regressions on test-day deviations of days in milk. Phenotypes P1, P2, and P3 were calculated for sires as solutions estimated from a random regression model fitted to milk yield. Because total milk yield, calculated as the sum of daily sire solutions, was correlated to P1 and P2 (r=0.30 ...
This study has confirmed large seasonal and daily variations of Rn in soil gas, developed models for the effects of temperature and moisture on air-water Rn partition, inhibited Rn diffusion from wet soil into sparse large air-filled pores and effects of diffusion into bedrock, demonstrated that organic matter is a major host for 226Ra in soils and that organic-bound Ra largely determines the proportion of 222Rn emanated to pore space, shown that in contrast 220Rn is emanated mainly from 224Ra in Fe-oxides, detected significant disequilibrium between 226Ra and 238U in organic matter and in some recent glacial soils, demonstrated by computer models that air convection driven by temperature differences is expected in moderately permeable soils on hillsides.
This study has confirmed large seasonal and daily variations of Rn in soil gas, developed models for the effects of temperature and moisture on air-water Rn partition, inhibited Rn diffusion from wet soil into sparse large air-filled pores and effects of diffusion into bedrock, demonstrated that organic matter is a major host for 226Ra in soils and that organic-bound Ra largely determines the proportion of 222Rn emanated to pore space, shown that in contrast 220Rn is emanated mainly from 224Ra in Fe-oxides, detected significant disequilibrium between 226Ra and 238U in organic matter and in some recent glacial soils, demonstrated by computer models that air convection driven by temperature differences is expected in moderately permeable soils on hillsides.
Objective.The interest of dental research in metal-free restorations has been rising in the last 20 years following the introduction of innovative all-ceramic materials in the daily practice. In particular, high strength ceramics and related CAD/CAM techniques have widely increased the clinical indications of metal-free prostheses, showing more favourable mechanical characteristics compared to the early ceramic materials.The purpose of the present paper is providing a brief review on the all-ceramic dental materials, evaluating pros and cons in the light of the most recent scientific results and of the authors? clinical experience.Materials. A structured review of the literature was given on the basis of medical and engineering papers published in the last decades on the use of dental cera...
Passive microwave soil moisture datasets can be used as an input to provide an integrated assessment of climate variability as it relates to agricultural production. The objective of this research was to examine three passive microwave derived soil moisture datasets over multiple growing seasons in contrasting Canadian agricultural environments. Absolute and relative soil moisture was evaluated from two globally available datasets from the Advanced Microwave Scanning Radiometer for EOS (AMSR-E) sensor using different retrieval algorithms, as well as relative soil wetness at a weekly scale from the Special Sensor Microwave/Imager (SSM/I) sensor. At a daily scale, the Land Parameter Retrieval Model (LPRM) provides a better estimate of surface soil moisture conditions than the National Snow a...
Experiments were carried out to test the hypothesis that instantaneous daily rates of egg-larval mortality of Pacific herring were higher at two oil-exposed sites than at two other sites not so exposed. Results showed that egg-larval mortality was twice as great in the oil-exposed areas as in the two non-oiled areas. Larval growth rates were also severely affected; they were about half of those measured in populations from other areas of the north Pacific Ocean. A cautionary note was introduced to the effect that the differences in the egg-larval mortality between oiled and control sites may have been influenced by differences in egg dessication, predation, and wave scouring, hence these results should not be construed as conclusive evidence of oil spill damage. 40 refs., 6 figs.
This study evaluated the clinical efficacy of treatment with oral risedronate (17.5?mg once daily) for 8?weeks in 11 Japanese patients with Paget?s disease of bone (PDB). Risedronate suppressed the excessive bone turnover associated with PDB and improved several biochemical markers, including serum alkaline phosphatase (ALP), serum bone-specific ALP (BALP), urinary deoxypyridinoline (DPD), and urinary cross-linked N-telopeptide of type 1 collagen (NTX). These markers began to decrease within about 2?weeks after the initiation of treatment in most patients, and the response persisted for up to 40?weeks after the cessation of treatment. Risedronate reduced pain by week 24 in most patients. According to quantitative bone scintigraphy, the lesion with the highest radioisotope (RI) uptake showe...
Ethnopharmacological relevance: Extracts of the roots of Scutellaria baicalensis Georgi (Labiatae) have been widely used to relieve fever related to bacterial infection and inflammatory diseases in traditional Korean medicine and have been reported to be effective in brain diseases. These experiments were conducted to examine the effects of oral administration of Scutellaria baicalensis extracts on the rescue of memory impairments induced by chronic cerebral hypoperfusion or chronic lipopolysaccharide (LPS) infusion. In addition, the underlying mechanisms of these effects were investigated. Materials and methods: In the first experiment, chronic cerebral hypoperfusion was induced in male Wister rats by bilateral common carotid artery occlusion (BCCAo). Daily administration of Scutellaria b...
Rationale Hypothalamic?pituitary?adrenal axis dysregulation predicts poor clinical and biochemical response to antidepressants. Antiglucocorticoids have therapeutic benefits but most have a troublesome adverse event profile. Aspects of neuropsychological performance, notably working memory, are susceptible to corticosteroid modulation and are impaired in depression. Aspirin has been shown to attenuate the adrenocorticotropic hormone (ACTH) and cortisol response to physiological challenge suggesting its potential to act as an augmenting agent in depression. Objectives To examine the effect of sub-acute (300?mg daily for 7?days) aspirin pre-treatment on the cortisol awakening response and the effect of acute (600?mg) and sub-acute aspirin on the neuroendocrine and neuropsychological response...
Plants require solar radiation for photosynthesis and their growth is directly related to the amount received, assuming that other environmental parameters are not limiting. Therefore, precise estimation of photosynthetically active radiation (PAR) is necessary to enhance overall accuracies of plant growth models. This study aimed to explore the PAR radiant flux in the San Francisco Bay Area of northern California. During the growing season (March through August) for 2?years 2007?2008, the on-site magnitudes of photosynthetic photon flux densities (PPFD) were investigated and then processed at both the hourly and daily time scales. Combined with global solar radiation (R S) and simulated extraterrestrial solar radiation, five PAR-related values were developed, i.e., flux density-based PAR ...
This document includes the following topics: Background; Data Collection; Scope/Applicability of the Proposed Regulation; Description of the Industry; Industry Subcategorization; Pollutants of Concern for the Centralized Waste Treatment Industry; Pollutants Selected for Regulation; Wastewater Treatment Technologies; Regulatory Options Considered and Selected for Basis of Regulation; Long-Term Averages, Variability Factors, and Limitations and Standards; Cost of Treatment Technologies; Pollutant Loading and Removal Estimates; Non-Water Quality Impacts; Implementation; Analytical Methods and Baseline Values; List of Definitions; List of Acronyms; Appendix A--Pollutant Groups; Appendix B--Listing of Characerization Data From Non-Hazardous Oils Facilities; Appendix C--Listing of Daily Influent and Effluent Measuements; Appendix D--Facility-Specific Compliance Costs; Appendix E--Attachements to Chapter 10; and Appendix F--Listing of Pollutants of Concern and Cas ...
Abstract A 3-month, open-label, single-center study was conducted to determine whether a uniquely formulated and physiologically balanced topical treatment serum containing multiple growth factors, cytokines, peptides, antioxidants and depigmenting agents could improve the visible signs of facial photodamage. Thirty-seven females, aged 32-55 years, with mild to severe, fine and coarse peri-ocular wrinkles were enrolled and completed the study. Subjects applied the treatment serum to the face twice daily for 3 months in conjunction with a basic skincare regimen. Clinical evaluations of photodamage were performed at baseline and months 1, 2 and 3. Cutometer measurements and subject self-assessment questionnaires were also conducted during the study. Clinical evaluations showed statistically ...
SummaryBackground Persistent Lyme Disease Symptoms (PLDS) have included fatigue, headaches, poor concentration and memory, lightheadedness, joint pain, and mood disturbances. Evidence-based guidelines committees disagree over the severity of PLDS. The 2004 International Lyme and Associated Diseases Society (ILADS) concluded that PLDS are severe. The 2006 Infectious Disease Society of America (IDSA) guidelines committee concluded that PLDS are nothing more than the "aches and pains of daily living" and an ad hoc International Lyme group concluded that PLDS are "symptoms common in persons who have never had Lyme disease." Hypothesis Clinical trials validate the severity of persistent Lyme disease symptoms. Evaluation of the Hypothesis There are 22 standardized instruments used to measure the...
This study evaluates the trends of meteorological and agrometeorological indices computed at different sites in the Region of Umbria (Central Italy). The indices were selected on the basis of whether they enable the evaluation of the potential effects of climatic changes on agricultural water requirements and management. The meteorological stations were preliminarily selected considering the length and entirety of the data series and a homogeneous spatial coverage of the region under study. The daily rainfall and minimum and maximum temperature data collected at the stations were elaborated to calculate meteorological and agrometeorological indices (for corn, widespread irrigated crop in Central Italy).The results of the analysis show that rainfall has decreased generally everywhere and th...
Excessive physical activity plays an important role in the progression of anorexia nervosa (AN) by accelerating weight loss during dietary restriction. To search for mechanisms underlying this trait, a panel of mouse chromosome substitution strains derived from C57BL/6J and A/J strains was exposed to a scheduled feeding paradigm and to voluntary running wheel (RW) access. Here, we showed that A/J chromosomes 4, 12 and 13 contribute to the development of a disrupted RW activity in response to daily restricted feeding. This pattern is characterized by intense RW activity during the habitual rest phase and leads to accelerated body weight loss. Regions on mouse chromosomes 4, 12 and 13 display homology with regions on human chromosomes linked with anxiety and obsessionality in AN cohorts. The...
Background: Chloroquine has in-vitro activity against influenza and could be an ideal candidate for worldwide prevention of influenza in the period between onset of a pandemic with a virulent influenza strain and the development and widespread dissemination of an effective vaccine. We aimed to assess the efficacy of such an intervention. Methods: In this randomised, double-blind, placebo-controlled trial done at a single centre in Singapore, we randomly assigned (1:1) healthy adults to receive chloroquine phosphate (500 mg/day for 1 week, then once a week to complete 12 weeks) or matching placebo by use of a computer-generated randomisation list. Participants filled an online symptom diary every week, supplemented by daily diaries and self-administered nasal swabs when unwell. Haemagglutin...
This report is a compilation of the Chalk Point surface weather and ambient atmospheric profile data for the second intensive test period, June 14-24, 1976. The atmospheric profiles were made using rawinsonde instrumentation. The compilation includes the 0700 EST daily weather chart, hourly surface observations from Chalk Point, Patuxent River Naval Test Center, MD and Andrews Air Force Base, MD. Temperature, relative humidity, dew point, wind speed and wind direction are presented in graphical profiles. All other data are presented in tabular form.
Proper balance control is a key aspect of acitivities of daily living. The aim of this study was to determine the contribution of body weight to predict balance stability. The balance stability of 59 male subjects with BMI ranging from 17.4 to 63.8kg/m2 was assessed using a force platform. The subjects were tested with and without vision. A stepwise multiple regression analysis was used to determine the independent effect of body weight, age, body height and foot length on balance stability (i.e., mean speed of the center of foot pressure). With vision, the stepwise multiple regression revealed that body weight accounted for 52% of the variance of balance stability. The addition of age contributed a further 3% to explain balance control. Without vision, body weight accounted for 54% of the...
The operation of pumped-storage plants (PSP) is based on the daily load variations of power demand. It performs power generation at peak load times during the day, and pumps water up into the reservoir during the off-peak times at night. In the Taipower system in Taiwan, there are two pumped storage plants with ten units. These had a total installed capacity of 2,602 MW or a 12 percent capacity at the end of 1995. The plants were able to reduce system generation costs and improve reliability. A Pumped-Storage Plant Benefit Analysis (PSPBA) program was established using the principle of economic dispatch in 1985. This paper explains the rules of the program, the analysis results of the past 10 years, and a a cost benefit evaluation. It was found that the advantages of PSP are not only in supplying the power for peak load, but also in decreasing the total fuel cost. 5 figs., 4 refs.
SummaryThis paper examines the sensitivity and uncertainty of evaporation estimates from Nasser Lake, south of Egypt using data collected at the floating station Raft, 2km upstream of the Aswan High Dam, and 12 evaporation models. Based on their approach the evaporation models were ranked in five classes, respectively the Bowen ratio energy budget (BREB) approach, three energy-aerodynamic based methods, a mass transfer method, two temperature and five solar radiation-temperature approaches. State dependent parameter models were used to estimate the sensitivity indices of the different evaporation estimation methods at daily and monthly frequencies. A drastic reduction in the cost of the sensitivity analysis was obtained when coupled with efficient sampling methods, producing quasi-Monte Ca...
An enriched culture 48, capable of adapting to the reservoir conditions and fermenting molasses to produce gas and acid, was used as an inoculum for bio- huff-`n`-puff tests at Fuyu oil area of Jilin oil field. The production well was injected with water containing 4-6% (v/v) molasses and inoculum, and then shut in. After 15-21 days, the well was placed back in operation. A total of 44 wells were treated, of which only two wells showed no effects. The daily oil production of treated wells increased by 33.3-733.3%. Up to the end of 1994, the oil production was increased by 204 tons per well on average. Results obtained from various types of production wells were discussed.
Determination of the radiocarbon (14C) content of airborne particulate matter yields insight into the proportion of the carbonaceous material derived from fossil and contemporary carbon sources. Daily samples of PM2.5 were collected by high-volume sampler at an urban background site in Birmingham, UK, and the fraction of 14C in both the total carbon, and in the organic and elemental carbon fractions, determined by two-stage combustion to CO2, graphitisation and quantification by accelerator mass spectrometry. OC and EC content was also determined by Sunset Analyzer. The mean fraction contemporary TC in the PM2.5 samples was 0.50 (range 0.27-0.66, n=26). There was no seasonality to the data, but there was a positive trend between fraction contemporary TC and magnitude of SOC/TC ratio and fo...
The paper describes, for the Hausa farmers of Gidan Jatau in northern Nigeria, the distinct ways in which they see and understand (a) their close and distant environment and (b) their bodies' anatomy and physiology. These ways result in 'another geography' - of both space and being - which, however, may no longer now have the resonance it had in the early 1970s when the author lived in Gidan Jatau for two years as a guest. At that time, the spiritual dimensions of daily life were deemed important to the health and prosperity of each person and to the farmstead as a whole. The argument is made that the urban-centred literature on the bori possession-cult neglects the ordinary, anonymous spirits of house and field. Any serious archaeology of the landscape will need insights into this 'altern...
The interscalenic block technique is widely used for ambulatory shoulder surgery despite a substantial number of failures and adverse effects. We prospectively evaluated satisfaction in 40 consecutive patients who underwent open Bankart repair under a single general anesthesic performed in an ambulatory care unit. The mean age of the patients was 23 years. There were 29 men and 11 women. Patients were evaluated postoperatively with a visual analog scale of pain (in the recovery room, at the time of discharge, and the day after and 1 week after surgery) via a home assessment questionnaire that included the following: effectiveness of oral pain medication, ability to perform activities of daily life, and overall satisfaction. One patient failed to be discharged because of a feeling of faintn...
Abstract Micronutrient deficiencies are a public health concern among young children in low-income countries, and novel strategies are needed to improve the nutritional status of children at risk. One promising approach is the use of lipid-based nutrient supplements (LNS), which can be added to complementary food at the time of consumption. The optimal amount of zinc to include in LNS is uncertain, and concerns have been expressed about possible adverse effects of zinc on sensory characteristics of LNS. We conducted a series of acceptability studies of LNS containing either 0 or 10-mg of zinc per daily 20-g LNS dose among Burkinabe children 9-15 months old and their mothers. These acceptability studies included observations of children's consumption, maternal and child sensory reaction to ...
Abstract Aims To determine, in the context of a trial in which counseling did not improve smoking cessation outcomes, whether this was due to a failure of the conceptual theory identifying treatment targets or the action theory specifying interventions. Design Data from a randomized clinical trial of smoking cessation counseling and bupropion SR were submitted to multi level modeling to test whether counseling influenced real time reports of cognitions, emotions and behaviors, and whether these targets predicted abstinence. Setting Center for Tobacco Research and Intervention, Madison, WI. Participants A total of 403 adult, daily smokers without contraindications to bupropion SR use. Participants were assigned randomly to receive individual counseling or no counseling and a 9 week course o...
The primary extrusion of Na+ from Mycoplasma gallisepticum cells was demonstrated by showing that when Na+-loaded cells were incubated with both glucose (10 mM) and the uncoupler SF6847 (0.4 microM),...Full Text Available
A previously healthy young man experienced several episodes of syncope while being treated with tenofovir, emtricitabine and nevirapine initiated during primary HIV-1 infection. Symptoms disappeared after discontinuation of antiretroviral therapy and we suggest that syncope may be a side effect to one of the three antiretroviral drugs that has not been described previously.
The right upper lung lobe of a 74 year old man was resected for a central tumour. Two primary cancers were found; a central small cell carcinoma and a peripheral squamous cell carcinoma. In addition,...Full Text Available
An e.p.r. spectrum of the reduced form of the electron-transport component (X), thought to be the primary electron acceptor of Photosystem I, was obtained. By using line-shape simulations of this component...Full Text Available
Purpose:To study the outcome of in-the-bag implanted square-edge polymethyl methacrylate (PMMA) intraocular lenses (IOL) with and without primary posterior capsulotomy in...Full Text Available
The management procedure of a large PRISE (Primary-to-Secondary) leakage accident at Loviisa nuclear power plant taking into account the plant modifications which are expected to be realized during 1995-96 is described. The management procedure has been validated by performing thermal hydraulic analyses with the computer code RELAP5/MOD3 and the results from these analyses are also shortly discussed. (4 refs., 6 figs., 1 tab.).
Primary Ewing's sarcoma of the skull is a very rare entity. We report MRI findings in a case of Ewing's sarcoma of the greater wing of sphenoid in a 4-year-old patient. Magnetic resonance imaging showed markedly heterogenous signal intensity with areas of haemorrhage and necrosis. It also demonstrated the exact extent of tumour due to its multiplanar capabilities and was, therefore, helpful in planning surgery. Copyright (2002) Blackwell Science Pty Ltd
Analytical techniques for analyzing the effects of ship motion and attitude on the primary coolant system flow rates are presented. Design data for minimizing these effects are given. (C.J.G.)
Primary dendrite spacings and side-branch coarsening kinetics were examined in specimens of the single-crystal multicomponent commercial superalloy PWA-1480, which were directionally solidified in a psoitive thermal gradient. The experimentally observed dependence of primary dendrite spacings and side-branch coarsening kinetics on growth rate and thermal gradient were in agreement with the behavior predicted by analytical models developed for binary alloys. (orig.).
Primary peritoneal malignant mixed mullerian tumors are very rare. We report the case of a patient presenting with pain in the right upper quadrant of the abdomen and in whom the physical examination demonstrated a peritoneal mass. Computed tomography (CT) confirmed the presence of a mass, with invasion of adjacent organs.
The authors present a case in which primary Ewing's sarcoma of the right petrous pyramid in a 9-year-old girl showed no uptake on a /sup 99m/Tc-pertechnetate nuclide angiogram. Intense uptake was present on a /sup 99m/Tc-polyphosphate bone scan, but a static brain scan was only minimally abnormal. The diagnosis and treatment of Ewing's sarcoma are reviewed.
A bone scan can be negative in Ewing's sarcoma. The bone scan during and after treatment can give prognostic information on the primary tumor site: A persisting hot spot strongly suggests the presence of local malignancy, while a hot spot becomming negative points to local cure of Ewing's sarcoma. (orig.).
Results of an investigation aiming to study the effects of the burner cap design factors on flame stability are presented in this paper. Flame stability is an essential part of the operation of all domestic burners, including natural gas-fired cooktops. At high thermal inputs flame lifts are encountered above certain levels of primary aeration, whereas flashback only takes place at low thermal inputs, due to natural gas low flame speed, above certain levels of primary aeration. In this work, flame lift limits were measured at 3.3 kW thermal input and the highest primary aeration above which flame lifts started to become visible was the stability limit at this thermal input. Around 60% primary aeration was desired to minimize pollutant emissions. Turndown tests were done at 40% primary aeration. The `Factorial Experimental Design` method with statistical analysis was used. This ...
Daily intakes of certain trace elements (Pb, Cd, Ni, Hg, and Cr) were assessed using dietary history and weighed record methods and concurrent chemical analysis (CA) of duplicate portions, along with blood levels, in a group (21 M, 23 F) of inhabitants of the Gubbio area (Belvedere, Biscina Scritto). The evaluation of only intake of trace elements was accomplished in 40 subjects (20 M, 20 F) 1 year later. In both surveys, trace element intakes were generally lower than the potential tolerable weekly intake. However, daily intakes of Pb, Cd, Ni, Hg, and Cr were higher in men compared to women in both surveys (P<0.05). In fact, intakes at the 50th percentile were greater in men by approximately 75% for Pb, 91% for Cd, 20% for Ni, 45% fo Hg, and 29% for Cr in the first survey. In the second survey, percentage differences for Pb, Cd, Ni, and Cr were about 12%, 28%, 26%, and 26%, respectively. Blood trace element levels were slightly higher in ...
Background: In the German CESS-studies, Ewing's sarcoma patients with pulmonary metastases at diagnosis were considered as candidates for additional bilateral lung irradiation. We have retrospectively analyzed the impact of radiotherapy on survival. Material and methods: Out of 42 patients presenting with pulmonary metastases of Ewing's sarcoma between 1981 and June 1992, 30 were evaluable. One patient died of progressive disease prior to lung irradiation. The other patients had a complete radiographic remission either after chemotherapy (n=25) or chemotherapy plus resection of lung metastases (n=4). 22 patients received bilateral lung irradiation with doses of 12 to 21 Gy (once daily 1.5 Gy or twice daily 1.25 Gy), six had no further treatment and one had bone marrow transplantation for consolidation. Results: Ten patients are in complete remission, nine of them had received lung irradiation and one had a complete resection of three lung ...
Due to a leakage from a 12-inch pressurized diesel steel pipe four years ago, an area of approximately 30,000 square meters was contaminated. A pilot study applying the technology of in-situ enhanced bioremediation was conducted. In the study, a field test kit and on-site monitoring equipment were applied for site characterization and treatment verification. Physically, the enhanced bioremediation study consisted of an air extraction and air supply system, and a nutrition supply network. Certain consistent sampling methodology was employed. Progress was verified by daily monitoring and monthly verification. The objective of this study was to evaluate the capabilities of indigenous microorganisms to biodegrade the petroleum hydrocarbons with provision of oxygen and nutrients. Nine extraction wells and eight air sparging wells were installed. The air sparging wells injected the air into geoformation and the extraction wells provided the underground air circulation. ...
Currently daily quality control (QC) tests for mammography systems are generally evaluated by using visual analysis phantoms, which of course means subjective measurement. In our study, however, we evaluated a novel digital phantom, the 1Shot Phantom M plus (1Shot Phantom), together with automatic analysis software dedicated for mammography systems using Fuji computed radiography (FCR). The digital phantom enables objective evaluation by providing for actual physical measurement rather than subjective visual assessment. We measured contrast to noise ratio (CNR), image receptor homogeneity, missed tissue at chest wall side, modulation transfer function (MTF), and geometric distortion utilizing the 1Shot Phantom. We then compared the values obtained using the 1Shot Phantom with values obtained from the European guidelines and International Electrotechnical Commission (IEC) standards. In addition, we evaluated the convenience of using the digital phantom. The values ...
In the green building of Shanghai Research Institute of Building Science, the evacuated tubular solar collectors with a total area of 150 m{sup 2} were installed to provide heating for the covered area of 460 m{sup 2}. The floor heating coil pipes were made of high-quality pure copper with the dimension of {phi} 12 x 0.7 mm. Under typical weather condition of Shanghai, the average heating capacity was 25.04 kW during the working hours from 9:00 to 17:00, which was sufficient to keep indoor thermal environment. The average electric COP of the floor heating system was 19.76 during the system operation. Compared with the widely used air-source heat pump heating systems with the electric COP of 3.5 in Shanghai, the solar-powered floor heating system shows great potential in energy conservation in winter. With respect to the whole heating period, the solar fraction was 56%. According to the performance analysis of the system with ambient parameters, it was observed that the system ...
This study examined the relationship between the 1997 UPE policy and regional educational and poverty inequality and its impact on lifelong learning through a one-year field based critical ethnography in Uganda, between June 2007 and May 2008. It drew on the Government's assumption that through UPE the twin goals of the universalisation of primary education and lifelong learning would be attained. This led to the concentration of resources away from higher education, secondary education, and lifelong learning to primary education. This 'UPE centric' approach ignored the precarious situation of the large number of illiterate children, youths and adults who have never accessed UPE or dropped out without attaining literacy and numeracy skills. This paper will clarify the relationship between ...
The morphology and size characteristics of the population of AlP particles produced by treatment of a pure aluminium melt with an Al-Fe-P inoculant addition have been determined. The particles are shown to be polyhedral like the primary silicon they nucleate in hypereutectic Al-Si alloy melts and to be prone to clustering at increased phosphorus addition levels. The number of AlP particles per unit area is shown to be comparable with the corresponding number density of polyhedral primary silicon in Al-20 wt.% Si treated in the same way under identical conditions which is consistent with earlier conclusions that AlP acts as a nucleation catalyst for primary silicon in hypereutectic Al-Si casting alloys. (orig.)
A major deficiency of current photon calculation methods that are based on the concept of primary and scatter separation is their inability to handle the condition of electronic disequilibrium. This deficiency is examined and it is shown that the limitation is not inherent in the algorithms themselves but is, at least in part, in the data which the algorithms use. A new concept of primary and scatter separation is developed to cover the condition of electronic disequilibrium. This new concept requires little change to the existing algorithms and only additional data are required, which are generated using Monte Carlo calculation methods. The new concept is tested using programs in the Theratronics Theraplan treatment-planning system, and two calculation examples illustrate the ability to model electron transport and also the improvement over the existing algorithms. Close analogy of the extended concept with the convolution/superposition method ...
The ISI (In-Service Inspection) system has been developed so as to maintain the structural integrity of heat transfer tubes in the primary pressurized water cooler in the HTTR (High Temperature Engineering Test Reactor). This system consists of eddy current probes, ultra-sonic probes, insertion and extraction units, positioning unit and so on. Verification and performance tests of the developed ISI system were carried out using mock-up heat transfer tubes in the primary pressurized water cooler. The constitution of the system, R and D results of the inspection probes, and verification and performance test results of the ISI system for heat transfer tubes are described in this paper. (author)
The ISI (In-Service Inspection) system has been developed so as to maintain the structural integrity of heat transfer tubes in the primary pressurized water cooler in the HTTR (High Temperature Engineering Test Reactor). This system consists of eddy current probes, ultra-sonic probes, insertion and extraction units, positioning unit and so on. Verification and performance tests of the developed ISI system were carried out using mock-up heat transfer tubes in the primary pressurized water cooler. The constitution of the system, R and D results of the inspection probes, and verification and performance test results of the ISI system for heat transfer tubes are described in this paper. (author)
Summary Objective To evaluate the cost-effectiveness of an educational outreach intervention to improve primary respiratory care by South African nurses. Methods Cost-effectiveness analysis alongside a pragmatic cluster randomised controlled trial, with individual patient data. The intervention, the Practical Approach to Lung Health in South Africa (PALSA), comprised educational outreach based on syndromic clinical practice guidelines for tuberculosis, asthma, chronic obstructive pulmonary disease, pneumonia and other respiratory diseases. The study included 1999 patients aged 15 or over with cough or difficult breathing, attending 40 primary care clinics staffed by nurses in the Free State province. They were interviewed at first presentation, and 1856 (93%) were interviewed 3 months late...
The relative merits and difficlties of the primary and secondry origin hypotheses for the observed cosmic-ray antiprotons, including the new low-energy measurement of Buffington, et al are discussed. We conclude that the cosmic-ray antiproton data may be evidence for antimatter galaxies and baryon symmetric cosmology. The present bar P data are consistent with a primary extragalactic component having /p /equiv 1+/- 3.2/0.7x10 to the -4 independent of energy. We propose that the primary extragalactic cosmic ray antiprotons are most likely from active galaxies and that expected disintegration of bar alpha/alpha ban alpha/alpha. We further predict a value for ban alpha/alpha /equiv 10 to the -5, within range of future cosmic ray detectors.
Abstract Purpose: To compare the safety and efficiency of conventional monopolar, plasmakinetic and holmium laser transurethral resection of bladder tumor (CM-TURBT, PK-TURBT and HoL-TURBT) while managing primary non-muscle invasive bladder cancer. Patients and Methods: From 2005 to 2009, 173 patients with primary non-muscle invasive bladder cancer underwent endoscopic surgery. Among them, 51 patients underwent CM-TURBT, 58 patients underwent PK-TURBT, and 64 patients underwent HoL-TURBT. All patients were divided into three risk groups (low, intermediate, and high) based on the European Association of Urology guidelines and prognostic factors of recurrence. Clinical data, included preoperative, operative, and postoperative management and follow-up, were recorded. Results: Patient demograp...
Bilateral breast carcinoma accounts for approximately 5% of all patients with breast cancer, while neuroendocrine breast carcinomas comprise less than 5% of invasive breast carcinomas. In addition, most patients with breast neuroendocrine carcinomas are older. Therefore, bilateral primary breast neuroendocrine carcinoma at a young age is extremely rare. We herein report bilateral neuroendocrine carcinoma of the breast in a 29-year-old woman who underwent bilateral lumpectomy with the initial symptom of bilateral nipple discharge. Grossly, the lesions in both breasts were masses with infinite margins. Histologically, this case was consistent with primary neuroendocrine carcinoma arising in bilateral breasts. Cells from both breast tumors were positive for chromogranin A, neuron-specific eno...
We show that the HACCP system is not fully applicable at the primary production level, and that food safety is obtained through the careful implementation of good hygiene practice (GHP) at the farm. Guides to GHP intended at primary productions cover one activity, such as cattle rearing or corn production. Yet most farms have more than one activity. Hazards from one activity can be transferred to another activity, and in general this is not considered in one-activity guides. There is a need therefore for farmers to be able to detect and control such transfers. We suggest a horizontal complement to the Guides to GHP that would consider only the application of the Step 6 and Principle 1 of the HACCP system amended as follows: ''List all potential hazards transferred from one activity to anot...
1. Eight deuteranopes matched a mixture of a monochromatic light on the long wave side of the neutral point and a violet (450 nm) primary to a fixed white as well as a monochromatic light on the short...Full Text Available
The central nervous system regulates peripheral immune responses via the vagus nerve, the primary neural component of the cholinergic anti-inflammatory pathway. Electrical stimulation of the...Full Text Available
Patients who fail to attend initial appointments reduce clinic efficiency. To maximize attendance by newly referred outpatients, we introduced a mandatory group orientation clinic for all new patients...Full Text Available
Objective To establish current practice in the use of Read codes for diabetes.Design Cross sectional study.Setting 17 practices in the Battersea...Full Text Available
The primary objective of our study is to describe urinary symptoms in women treated for endometrial cancer. We performed a cross-sectional survey of women who had undergone surgical treatment...Full Text Available
Accessory cusp present on the occlusal surface may seldom pose problems. While its presence may not be a cause for alarm in most instances, it can sometimes lead to serious consequences if it is damaged....Full Text Available
BackgroundExisting studies concerning the health care use of homeless people describe higher utilisation rates for hospital-based care and emergency care, and lower rates for primary...Full Text Available
This study was undertaken to determine which rodent species serve as primary reservoirs for the Lyme disease spirochete Borrelia burgdorferi in commonly occurring woodland types...Full Text Available
Current genome-wide association studies (GWAS) are moving towards the use of large cohorts of primary cell lines to study a disease of interest and to assign biological relevance to the genetic signals...Full Text Available
In the convolution/superposition method of photon beam dose calculations, inhomogeneities are usually handled by using some form of scaling involving the relative electron densities of the inhomogeneities. In this paper the accuracy of density scaling as applied to primary electrons generated in photon interactions is examined. Monte Carlo calculations are compared with density scaling calculations for air and cork slab inhomogeneities. For individual primary photon kernels as well as for photon interactions restricted to a thin layer, the results can differ significantly, by up to 50%, between the two calculations. However, for realistic photon beams where interactions occur throughout the whole irradiated volume, the discrepancies are much less severe. The discrepancies for the kernel calculation are attributed to the scattering characteristics of the electrons and the consequent oversimplified modeling used in the density scaling method. A ...
Opinions on factors affecting public power systems are presented. Social, economic, and political factors are discussed in terms of their impact on public power. Competition with investor-owned utilities is the primary focus of the paper. Privatization and regulations are other issues discussed.
BackgroundMost studies on children with chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME) have been undertaken in tertiary care and little is known about their management...Full Text Available
The effects of bovine α-globulin (BAG), bovine-ribonuclease serum albumin (BSA-RNase) and polyribonuclease (poly-RNase) complexes on the primary response of rodents to sheep erythrocytes have...Full Text Available
Chronic heart failure (HF) is a cardiovascular disease of cardinal importance because of several factors: a) an increasing occurrence due to the aging of the population, primary and secondary prevention...Full Text Available
After more than a decade of the AIDS epidemic in Thailand, the number of children whose parents are living with HIV or have died from AIDS is increasing significantly and it has been reported that these...Full Text Available
Shoulder pain is a common orthopedic condition seen by physical therapists, with many potential contributing factors and proposed treatments. Although manual physical therapy interventions for the cervicothoracic...Full Text Available
Clarifies the concept of universal basic education. Highlights the need for performance criteria and ways to measure literacy attainment. Identifies issues related to improving primary education, seeing adult literacy as its necessary complement. Underscores the substantial resources required to achieve universal basic education. (CH)
This book constitutes a portion of the primary documentation for the 1992 Pacific Northwest Residential Energy Survey, Phase I. The complete 33-volume set of primary documentation provides information needed by energy analysts and interpreters with respect to planning, execution, data collection, and data management of the PNWRES92-I process. Thirty of these volumes are devoted to different ``views`` of the data themselves, with each view having a special purpose or interest as its focus. Analyses and interpretations of these data will be the subjects of forthcoming publications. Conducted during the late summer and fall months of 1992, PNWRES92-I had the over-arching goal of satisfying basic requirements for a variety of information about the stock of residential units in Bonneville`s service region. Surveys with a similar goal were conducted in 1979 and 1983. This volume contains a follow-up study of non-respondents to the original survey. ...
BackgroundInternationally, there is increasing use of telephone consultations, particularly for triaging requests for acute care. However, little is known about how this mode of...Full Text Available
BackgroundVisual neurons respond essentially to luminance variations occurring within their receptive fields. In primary visual cortex, each neuron is a filter for stimulus features...Full Text Available
BackgroundXenotropic Murine Leukemia Virus-related (XMRV) virus is a recently identified mouse gammaretrovirus that has the ability to infect certain human cells. In this study,...Full Text Available
Accompanying rapid developments in hepatic surgery, the number of surgeries and identifications of histological types of primary hepatic space-occupying lesions (PHSOLs) have increased dramatically....Full Text Available
The variation in the superconducting properties of various binary alloys of transition metal-germanium systems was surveyed by studying sputter deposited samples prepared under various conditions. The primary interest has been to study the formation of the stoichiometric A-15 compounds T_3Ge.
BackgroundThe study of small airway diseases such as post-transplant bronchiolitis obliterans syndrome (BOS) is hampered by the difficulty in assessing peripheral airway function...Full Text Available
Terminal differentiation of many vascular cells involves cell wall changes. Cells first elongate their primary wall, then lay down a lignified secondary wall, which is often followed by digestion of...Full Text Available
The primary E1, M1 and E2 ..gamma..-radiation in /sup 87,88,89/Sr observed after thermal neutron capture was compared with the predictions of single particle and giant resonance models. The nuclei feature a wide range of neutron binding energies between 6.3 and 11.1 MeV, which makes a 5.5 MeV spectrum of primary transition energies available for investigation. The (n, ..gamma..) reaction was used to estimate the parameters of the spin-flip M1 giant resonance in strontium. The total energy weighted M1 strength of this resonance exceeds the results of shell model and random phase approximation calculations for /sup 90/Zr by a factor of 3-4. The E1 strengths were found to agree with the established giant dipole resonance model. The few data on primary E2 transitions do not allow to differentiate between the giant quadrupole resonance and the single particle models.
The primary E1, M1 and E2 #gamma#-radiation in "8"7","8"8","8"9Sr observed after thermal neutron capture was compared with the predictions of single particle and giant resonance models. The nuclei feature a wide range of neutron binding energies between 6.3 and 11.1 MeV, which makes a 5.5 MeV spectrum of primary transition energies available for investigation. The (n, #gamma#) reaction was used to estimate the parameters of the spin-flip M1 giant resonance in strontium. The total energy weighted M1 strength of this resonance exceeds the results of shell model and random phase approximation calculations for "9"0Zr by a factor of 3-4. The E1 strengths were found to agree with the established giant dipole resonance model. The few data on primary E2 transitions do not allow to differentiate between the giant quadrupole resonance and the single particle models. (orig.).
Purpose: This paper reviews and reassesses the internationally accepted niches or ‘targets’ in bone marrow that are sensitive to the induction of leukaemia and primary...Full Text Available
The Space Task Group in its study of future directions in space, with ..... almost $6 billion and a peak civil service and contractor work force of 420000 people. ..... space organizations permitting assumptions of primary or joint responsibility for ...
Clostridium thermohydrosulfuricum and Clostridium thermosulfurogenes produced ethanol and amylases with different components as primary metabolites of starch fermentation....Full Text Available
BackgroundSilica nanoparticles (SiNPs) are being formulated for cellular imaging and for nonviral gene delivery in the central nervous system (CNS), but it is unclear what potential...Full Text Available
Between 1946 and 1976 over 9,000 women with breast cancer were seen within one year of diagnosis at the A. Maxwell Evans Clinic (AMEC) in Vancouver, British Columbia. By 1978, 275 had a subsequent diagnosis...Full Text Available
The establishment of the primary meristems through proliferation after germination is essential for plant post-embryonic development. Cytokinins have long been considered a key regulator of...Full Text Available
Background: The outcome of acute myocardial infarction (AMI) complicated with cardiogenic shock is poor. The aim of this study was to analyse, whether upfront abciximab administration could improve the outcomes of cardiogenic shock. Methods: This multicentre open trial randomized 80 patients with AMI complicated by cardiogenic shock expected to undergo primary PCI into group A (routine upfront-pre-procedural-abciximab bolus followed by 12-h abciximab infusion) and group B (standard therapy). The study primary objective was 30-day combined outcome (death/reinfarction/stroke/new severe renal failure). Results: PCI was technically successful in 90% (A) versus 87.5% (B) patients. Abciximab was used in 100% (A) versus 35% (B). The primary endpoint occurred in 17 group A patients (42.5%) and 11 ...
Recurrent or primary carcinoma of the breast en cuirasse, which may involve the skin of the entire thorax and abdomen, cannot be controlled by means of surgery or conventional local irradiation. The...Full Text Available
This paper examines the current military working dogs (MWD) program, its historical roots, and the possibility for expansion of the program. Current service MWD programs will be discussed, as well as possible models for change. The primary focus is on the...
The levels of glucose, sugar phosphates, and adenosine phosphates were determined in primary leaves of intact bean plants during normal senescence and compared to leaves in which senescence was delayed...Full Text Available
Hepatitis B virus (HBV) DNA integration has been shown to occur frequently in human hepatocellular carcinomas. We have investigated whether common cellular DNA domains might be rearranged, possibly...Full Text Available
BackgroundThe circadian rhythm in mammals is orchestrated by a central pacemaker in the brain, but most peripheral tissues contain their own intrinsic circadian oscillators. The...Full Text Available
ObjectiveTo test whether a disclosure intervention improves subjective health and reduces medical consumption and sick leave in somatising patients in general practice.DesignNon-blind...Full Text Available
Deforestation is rapidly transforming primary forests across the tropics into human-dominated landscapes. Consequently, conservationists need to understand how different taxa respond and adapt to these...Full Text Available
SUMMARYSmall bowel epithelium is at the frontline of intestinal barrier function. Restitution is considered to be the major determinant of epithelial repair as function recovers...Full Text Available
We have examined the expression and structure of several genes belonging to two classes of vegetative specific genes of the simple eukaryote, Dictyostelium discoideum. In amebae grown on bacteria, deactivation...Full Text Available
A 6-year-old female, intact boxer presented with acute respiratory distress due to a mass in the left cranial thorax. The tumor, which originated in the left ...Full Text Available
A pore-forming peptide is implicated in the potent cytolytic activity of pathogenic Entamoeba histolytica. Using NH2-terminal sequence information of this peptide, the corresponding cDNA was isolated....Full Text Available
While most cancer survivors are at risk for being lost in the transition from treatment to survivorship, rural breast cancer survivors face special challenges that might place them at particular...Full Text Available
Eight recreational parks located in a Lyme disease endemic area of southern New York State were surveyed for the presence of ticks during the summer of 1985 by drag sampling. Ixodes dammini, the primary...Full Text Available
Previous studies in several different trigeminal nerve injury/inflammation models indicated that the hyperexcitability of primary afferent neurons contributes to the pain pathway underlying mechanical...Full Text Available
ASTROSAT, India's first dedicated astronomy satellite is slated for launch in 2007. The primary science objective of ASTROSAT is to explore the Universe using broad-band instruments covering optical, UV, soft X-ray and hard X-ray studies
BackgroundPolymorphisms in Epidermal Growth Factor Receptor (EGFR) gene may influence EGFR production and/or activity, thereby modulating susceptibility to lung...Full Text Available
Experiments were carried out to determine whether platelet aggregation plays a primary role in cardiac allograft hyperacute rejection, as has been observed in renal allograft hyperacute rejection....Full Text Available
Auditory conditioning (associative learning) causes reorganization of the cochleotopic (frequency) maps of the primary auditory cortex (AI) and the inferior colliculus. Focal electric stimulation...Full Text Available
Diseases of man caused by the virus of herpes simplex fall into two broad categories. The primary disease occurs only once in any individual's life and is caused by transmission of virus from an already...Full Text Available
ObjectiveThe primary objective of this study was to assess whether pentagastrin-induced panic symptoms are associated with release of free fatty acids (FFAs) in a manner that could...Full Text Available
IntroductionPrimary tumors of the breast containing bone and cartilage are extremely rare, and an osteogenic sarcoma arising from a cystosarcoma phyllodes is exceptional.Case...Full Text Available
The intercalated disk (ID) is a complex structure that electromechanically couples adjoining cardiac myocytes into a functional syncitium. The integrity of the disk is essential for normal cardiac function,...Full Text Available
W. Wayne Scott. ABSTRClCT. Primary proton and secondary particle doses (both .... W. Wayne Scott and R. G. Alsmiller, Jr., Comparisons of Results Ob- ...
BackgroundThe lack of adequate randomized clinical trials (RCT) has hindered identification of new therapies that are safe and effective for patients with primary focal segmental...Full Text Available
Adipose tissue is central to the regulation of energy balance. Two functionally different types of fat are present in mammals: white adipose tissue (WAT), the primary site of triglyceride storage,...Full Text Available
Treating brain tumors using inhibitors of angiogenesis is extensively researched and tested in clinical trials. Although anti-angiogenic treatment holds a great potential for treating primary and secondary...Full Text Available
...Agriculture Analysis of food supply chains and linkages in relation to quality and safety assurances Dept of Primary Industries, Australia Impact of food chain quality assurance requirements on farmer adoption and competitiveness UK Research Councils Review of environmental certification through farm assurance followed by industry developmental workshop Agriculture & ...
Aluminium (Al3+) toxicity is the primary factor limiting crop production on acidic soils worldwide. In addition to an application of lime for soil amelioration, Al3+ resistant plant varieties have been deployed to raise productivity on such hostile soils. This has been possible due to the exploita...
A number of studies have examined the functional roles of individual muscles during normal walking, but few studies have examined which are the primary muscles that respond to changes in external...Full Text Available
Mitochondrial heat shock protein 70 (mtHSP70) is found to play a primary role in cellular defense against physiological stress like exposure to environmental contaminants and helpful in the maintenance...Full Text Available
The primary aim of this study was to develop a model system that uses epidermal cells (keratinocytes and accessory pigmented cells) cultured on a reconstituted basement membrane biomatrix for use in...Full Text Available
Muscular dystrophies (MDs) comprise a group of degenerative muscle disorders characterized by progressive muscle wasting and often premature death. The primary defect common to most MDs involves disruption...Full Text Available
Our primary objective was to determine whether recent procurements of military working dogs by the 341st Training Squadron complied with section 10a, title 41, United States Code (41 U.S.C. 10a commonly known as the Buy American Act) and other procurement...
OBJECTIVE. This study was conducted to determine whether an index for measuring quality of care for psychiatric emergencies is reliable and valid. DATA SOURCES/STUDY SETTING. The study used primary...Full Text Available
The prognosis for patients with newly diagnosed malignant gliomas remains poor; however there have been some recent advances in treatment that have generated optimism. Medical management usually includes...Full Text Available
E-cadherin is the primary cell adhesion molecule within the epithelium, and loss of this protein is associated with a more aggressive tumour phenotype and poorer patient prognosis in many cancers. Loss...Full Text Available
Bone metastasis of primary colorectal cancer is uncommon. When it occurs, it is usually a late manifestation of disease and is indicative of poor prognosis. We describe a patient with multiple metachronous...Full Text Available
Recent advances in elastic-plastic fracture mechanics have made it possible to assess the stability of cracks in ductile piping systems. These technological developments have been used by Ontario Hydro as the nucleus of an approach for demonstrating that CANDU primary heat transport piping systems will not break catastrophically; at worst they would leak at a detectable rate. This leak-before-break approach has been taken on the Darlington nuclear generating station as a design stage alternative to the provision of pipe whip restraints on large diameter, primary heat transport system piping. Positive conclusions reached via this approach are considered sufficient to exclude the requirement to provide protective devices, such as pipe whip restraints. In arriving at the proposed leak-before-break approach a review of current and proposed leak-before-break licensing positions of other jurisdictions (particularly those in the United States and the ...
The case of an unusual late metastasis of neuroblastoma to the calcaneum, appearing as a sole recurrence 9 years after surgery, is reported. The radiographic features of the osseous lesion were very suggestive of primary bone malignancy, Ewing's sarcoma as the first option, with extraosseous spread to the soft tissues. (orig.).
... were erroneous. The oriental rat flea, Xenopsylla cheopis Rothschild, is considered to be the primary vector of ... laboratory and production of Weigl's exanthematous typhus vaccine. In Maintenance of hum...
[Leu]- and [Met]enkephalin from thoracic ganglia of the shore crab Carcinus maenas have been purified to homogeneity by a reversed-phase HPLC procedure. Automated gas-phase sequencing revealed a primary...Full Text Available
During attempts to establish tissue cultures from hepatopancreas, heart, and hemolymph of the giant tiger prawn (Penaeus monodon), using a medium including penicillin, streptomycin, and amphotericin...Full Text Available
By the time of primary 21st century, water hyacinth had become a serious environmental problem in China. Water hyacinth contributes to the major part of ecological hazards from the invasion of foreign...Full Text Available
BackgroundWe have recently reported successful treatment of patients with chronic pain syndromes using human pooled intravenous immunoglobulin (IVIG) in a prospective, open-label...Full Text Available
In the somatosensory domain it is still unclear at which processing stage information reaches the opposite hemispheres. Due to dense transcallosal connections, the secondary somatosensory cortex (S2)...Full Text Available
Typical aircraft types supported include F4-Phantom, Tornado, MiG-29 ...... attempt to develop a theoretical explanation for learning phenomena [16]. ..... perspective, a primary reason for this is that an exponential curve approximates ...
Late last year the Wolsung Candu in Korea suffered an incident which resulted in heavy water being released from the primary system into the containment. With the unit now back at full power, this article examines the causes of the incident and the action which is being taken to prevent it happening again.
Two Brucella fractions, the murein-linked fraction PI and the murein-free fraction SF, behave as in vitro adjuvants for primary anti-sheep erythrocyte responses: added to Mishell and Dutton-type cultures...Full Text Available
Elevated pH operation to the pH value of 7.3 at 285degC is known to be effective for the reduction of radiation source in the primary water system of PWRs. A research project was started in 1989 and concluded in 1996 to study and verify the optimum pH and/or Li concentration from the viewpoint of radiation source reduction and materials integrity under improved water chemistry. This research project is sponsored by the Ministry of International Trade and Industries (MITI) in Japan and has two programs; high pH and high Li. The high Li program was conducted to establish the optimum Li concentration for the high boron concentration region (1100 - 1800 ppm) of the high burn up operation. In this paper, we shall discuss radiation source behavior under high pH conditions and PWSCC (Primary Water Stress Corrosion Cracking) susceptibility of materials with change of primary water chemistry conditions and the improved water ...
The extent of our reliance on animal pollination for world crop production for human food has not previously been evaluated and the previous estimates for countries or continents have seldom used primary...Full Text Available
Autoimmune cholangitis would be the appropriate name to define the immune-mediated bile duct injury following the breakdown of tolerance to mitochondrial proteins and the appearance of serum autoantibodies...Full Text Available
ContextResponse Evaluation Criteria in Solid Tumors [RECIST (unidimensional)], World Health Organization [WHO (bi-dimensional)] and European Association for Study...Full Text Available
BackgroundDNA repair is the general term for the collection of critical mechanisms which repair many forms of DNA damage such as methylation or ionizing radiation. DNA repair has...Full Text Available
Osteoblasts are the primary cells responsible for bone formation. They also support osteoclast formation from bone marrow precursors in response to osteotropic factors by inducing receptor activator...Full Text Available
The principal cause of primary non-function in orthotopic liver transplantation is thought to be preservation injury to the microvasculature. We, therefore, evaluated if effluent levels of hyaluronate,...Full Text Available
BackgroundPromoter region plays an important role in determining where the transcription of a particular gene should be initiated. Computational prediction of eukaryotic Pol II promoter...Full Text Available
The content of guanine+cytosine varies markedly along the chromosomes of homeotherms and great effort has been devoted to studying this heterogeneity and its biological implications. Already...Full Text Available
We describe a rare case of a primary intracranial meningeal hemangiopericytoma (HPC) with late metastasis to the cervical spine. A 36-year-old woman had a left occipital lesion that was histopathologically...Full Text Available
BackgroundThe burden of non-communicable diseases, including type 2 diabetes, is growing in South Africa. This country has a complex mix of over- and under-nutrition, especially...Full Text Available
OBJECTIVE--To review findings from studies of the influence of desktop computers on primary care consultations. DESIGN--Systematic review of world reports from 1984 to 1994. SETTING--The computerised...Full Text Available
Use of geothermal resources for generating electricity is briefly analyzed. Results obtained from optimization of the thermodynamic cycle implemented in the secondary coolant circuit of a binary geothermal power station and the parameters of its primary heat carrier circuit are presented.
... Radon gas concentrations are measured using instruments with calibrations traceable to the UK National Physical Laboratory and PTB, Germany. The primary facility is a 43 m3 walk-in chamber accessed by an airlock. Radon gas is maintained at a level in this chamber that is ...
Purpose of reviewSevere congenital neutropenia (SCN) is a primary immunodeficiency in which lack of neutrophils causes inadequate innate immune host response to bacterial...Full Text Available
BackgroundParathyroid adenomas constitute the most common entity in primary hyperparathyroidism, and although recent advances have been made regarding the underlying genetic cause...Full Text Available
Assessment of subtle changes in the primary macromolecular components of cartilage, proteoglycan (PG) and collagen, is critical for the diagnosis of early stages of osteoarthritis (OA), but...Full Text Available
Finasteride, a specific and competitive inhibitor of 5α-reductase enzyme Type 2, inhibits the conversion of testosterone to dihydrotestosterone (DHT). In adults, DHT acts as primary androgen...Full Text Available
An overview is presented of the FFTF reactor and plant together with descriptions of core components, core internals, core system, primary and secondary control rod system, reactor instrumentation, reactor vessel and closure head, and supporting test programs. (DG)
An overview is presented of the FFTF reactor and plant together with descriptions of core components, core internals, core system, primary and secondary control rod system, reactor instrumentation, reactor vessel and closure head, and supporting test programs.
Rodent models have been extensively utilized to identify putative human immunotoxicants; however, even when immunotoxicity is established, uncertainty remains whether the effects are predictive of human...Full Text Available
Environmental health concerns in the Persian Gulf are peculiar to the geography of the region. Prevention of heat and solar injury deserves primary consideration, but cold injury also may occur in the...Full Text Available
A survey on electric power and on energy balance especially primary and final energy (gas oil, kerosene,solar energy...) has been implemented in Lebanon in 1993. Results and economic impact of energy consumption and energy production are given in statistics and tables. 10 figs.
The notes describe in detail primary and secondary galvanic cells, fuel cells, electrochemical synthesis and electroplating processes, corrosion: measurments, inhibitors, cathodic and anodic protection, details of metal dissolution reactions, Pourbaix diagrams and purification of waste water from galvanic industries.
OBJECTIVES: The ability to maximally generate active muscle tension during resistance training has been established to be a primary determinant for strength development. The influence of intrasession...Full Text Available
Bitter orange (Citrus aurantium) extract is widely used in dietary supplements for weight management and sports performance. Its primary protoalkaloid is p-synephrine....Full Text Available
Primary cell walls, free from cytoplasmic contamination were prepared from corn (Zea mays L.) roots and potato (Solanum tuberosum) tubers. After EDTA treatment, the...Full Text Available
Investigations are discussed carried out in a pilot plant at the Kaz. Power Engineering Scientific Research Institute into the effect of the amount of primary air in coal-dust flame on the final concentration of nitrogen oxides in flue gases. The tests were carried out in a 7500 mm high, 1600 mm dia vertical cylindrical combustion chamber having type P-57 burner, and air dispersed fuel plus additional air supplies located at the top. Amounts of coal dust fed by a drum feeder along the air pipe varied from 100-600 kg/h. The required air was supplied by 5000 m/sup 3//h Type TK-700/5 blowers at 0.04 MPa. Ehkibastuz coal samples contained: 1.3% moisture; 48.1% ash; 38.02% carbon; 2.56% hydrogen; 0.73% sulfur; 0.60% nitrogen; heat of combustion was 14.3 MJ/kg. Results obtained indicate that variations in the amount of primary air in swirl flow burners affect formation of fuel nitrogen; there is an optimum volume at which minimum quantities of ...
In response to reports that the contamination of food can occur during the on-farm primary phase of food production, we report data that describes a possible cost-effective intervention measure. The...Full Text Available
BackgroundGene duplication is the primary force of new gene evolution. Deciphering whether a pair of duplicated genes has evolved divergent functions is often challenging. The zebrafish...Full Text Available
Although skin is usually exposed during human exposures to ionizing radiation, there have been no thorough examinations of the transcriptional response of skin fibroblasts and keratinocytes...Full Text Available
The primary mode of transmission of Helicobacter pylori, a human pathogen carried by more than half the population worldwide, is still unresolved. Some epidemiological data suggest...Full Text Available
BackgroundChina has had no effective and systematic information system to provide guidance for strengthening PHC (Primary Health Care) or account to citizens on progress. We report...Full Text Available
Details of ion transporting abnormalities in cystic fibrosis airway epithelium are now known. The central hypothesis, that excessive drying of the airway surfaces is a primary event that leads to all...Full Text Available
Ewing sarcoma (ES) is the second most common type of primary bone malignancy in children and young adults. Survival rates for localized ES have improved to upwards of 70% with aggressive chemotherapy...Full Text Available
BackgroundEffective prevention of excessive alcohol use has the potential to reduce the public burden of disease considerably. We investigated the cost-effectiveness of Screening...Full Text Available
Significant progress was made in the May 1990--May 1991 contract period in three primary coal liquefaction research areas: catalysis, structure-reactivity studies, and novel liquefaction processes. A brief summary of the accomplishments in the past year in each of these areas is given.
In the presentation the major factors determining the conditions of NCC (Natural Coolant Circulation) in the primary circuit and in particular conditions of coolant rate distribution on the horizontal tubes of PGV-1000 in NPP with VVER-1000 under NCC are considered. 5 refs.
BackgroundMany health care professionals use spinal palpatory exams as a primary and well-accepted part of the evaluation of spinal pathology. However, few studies have explored...Full Text Available
Quantitative metallography is often used to confirm the proper processing of aerospace metallic materials. A microstructural feature of great importance for titanium alloys processed in the alpha-beta phase field is the volume fraction of primary alpha. S...
PURPOSE The Wells rule is widely used for clinical assessment of patients with suspected deep vein thrombosis (DVT), especially in the secondary care setting. Recently a new clinical decision...Full Text Available
We cloned and sequenced structural gene choM, which encodes an insecticidally active cholesterol oxidase in Streptomyces sp. strain A19249. The primary translation product was predicted to be a 547-amino-acid...Full Text Available
Species differences in lifespan have been attributed to cellular survival during various stressors, designated here as ‘cell resilience’. In primary fibroblast cultures, cell...Full Text Available
The use of cementless threaded cups in THA is a well-established treatment. Fractures of the cups are rare complications recorded in individual cases with material defects being discussed as the primary...Full Text Available
The pharynx is the primary reservoir for strains of group A Streptococcus (GAS) associated both with pharyngitis (streptococcal sore throat) and with invasive or “flesh-eating”...Full Text Available
Burner for feeding a solid and a liquid or gaseous fuel to a kiln comprises a central supply pipe for liquid or gas surrounded concentrically by a first pipe providing an annular passage through which primary air is supplied. Concentrically surrounding that pipe is a second pipe providing an annular channel for supply of solid fuel in carrier air stream. The outlet end of the first concentric pipe is closed by a plate fixed mounted at the pipe end and providing multiple nozzles having their axes parallel to the burner axis. The surface of the plate facing the burning zone provides a divergence opening for the central pipe while the inner surface is formed with helical teeth. These are engaged by complementary teeth mounted on the end of the central pipe which is rotatable and biased by springs so that the teeth are in engagement. Rotation of the pipe causes relative axial motion of the teeth to create tangential slots for admission of primary ...
Remote sensing data over North America document the ubiquity of secondary aerosols resulting from a combination of primary biogenic and anthropogenic emissions. The spatial and temporal distribution...Full Text Available
Sarcomas usually metastasize to lugs. The following case report describes an unusual metastasis of Ewing's sarcoma to extradural parietal region bilaterally. The primary was found at lower end of ulna. (author)
BK virus (BKV) is a polyomavirus that ubiquitously infects the human population. Following a typically subclinical primary infection, BKV establishes a lifelong persistent infection in the kidney...Full Text Available
BackgroundComputer-based health-risk assessments are electronic surveys which can be completed by patients privately, for example during their waiting time...Full Text Available
We report an unusual patient with primary adenocarcinoma of lung causing malignant pleural and pericardial effusions. The diagnosis was made only at autopsy as his staging computed tomography scan of...Full Text Available
Platelet Factor VIII-related antigen (VIIIR:Ag) represents a significant proportion of the total circulating VIIIR:Ag pool. However, its participation in the events of primary hemostasis has not been...Full Text Available
Saccharococcus sacchari is the primary colonizer of the developing “sterile” tissue between the leaf sheath and stem of sugar cane. The honeydew secreted by the mealybugs...Full Text Available
The paper presents the procedure of an investigation of WWER-1000 primary circuit temperature-stress field by the use of thermohydraulic computation data for a pressurized thermal shock event ''Core overcooling''. The procedure is based on a model of the plane stress state with ideal contact between wall and medium for the calculation. The computation data are calculated on the base of WWER-1000 thermohydraulic model by the RELAP5/MOD3 codes. This model was developed jointly by the Bulgarian and BNL/USA staff to provide an analytical tool for performing safety analysis. As a result of calculations by codes the computation data for temperature field law (linear laws of a few distinguished parts) and pressure of coolant at points on inner surface of WWER-1000 primary circuit equipment are received. Such calculations can be used as a base for determination of all-important load-carrying sections of the primary circuit pipes ...
KLF1 regulates a diverse suite of genes to direct erythroid cell differentiation from bipotent progenitors. To determine the local cis-regulatory contexts and transcription factor networks...Full Text Available
BackgroundStable transgenesis is an undeniable key to understanding any genetic system. Retrovirus-based insertional strategies, which feature several technical challenges when they...Full Text Available
Picocyanobacteria of the genus Synechococcus are important contributors to marine primary production and are ubiquitous in the world's oceans. This genus is genetically diverse, and...Full Text Available
Software for gel image analysis and base-calling in fluorescence-based sequencing consisting of two primary programs, BaseFinder and GelImager, is described. BaseFinder is a framework for trace processing,...Full Text Available
BackgroundMost traditional Chinese herbal formulas consist of at least four herbs. Four-Agents-Decoction (Si Wu Tang) is a documented eight hundred year old formula containing four...Full Text Available
BackgroundThe Emergency Care Summary (ECS) was introduced in 2006 to allow aspects of the general practitioner (GP; family doctor, equivalent to primary care physician) medical record...Full Text Available
The primary method for neuronal communication involves the extracellular release of small molecules that are packaged in secretory vesicles. We have developed a platform to separate, lyse, and...Full Text Available
Hepatocellular carcinoma (HCC) is a primary malignancy of the liver, which is closely related to hepatitis C and cirrhosis. The molecular mechanisms underlying the hepatocarcinogenesis induced by HCV...Full Text Available
Developing in vitro engineered hepatic tissues that exhibit stable phenotype is a major challenge in the field of hepatic tissue engineering. However, the rapid dedifferentiation of...Full Text Available
Scattered radiation generated in patient and imaging system has to be considered when quality-assurance tests involve dose detection or image-quality estimations. Measurement of automatic-exposure control dose can be altered by backscattering from intensifying screens of more than 10% and the equipment transmission factor can be overestimated up to a factor of 10 when only primary radiation is used. The sensitivity of intensifying screens depends on the angle of incidence of the radiation and so primary and scattered radiation are detected differently. The quality-control aspects of anti-scatter grids are discussed. (author).
Scattered radiation generated in patient and imaging system has to be considered when quality-assurance tests involve dose detection or image-quality estimations. Measurement of automatic-exposure control dose can be altered by backscattering from intensifying screens of more than 10% and the equipment transmission factor can be overestimated up to a factor of 10 when only primary radiation is used. The sensitivity of intensifying screens depends on the angle of incidence of the radiation and so primary and scattered radiation are detected differently. The quality-control aspects of anti-scatter grids are discussed. (author).
It is shown that multipole dislocation configurations can arise during power-law creep of certain austenitic stainless steels. These multipoles have been analysed in some detail for two particular steels (Alloy 800 and a modified AISI 316L) and it is suggested that they arise either during instantaneous loading or during the primary creep stage. Trace analysis has shown that the multipoles are confined to {1 1 1} planes during primary creep but are not necessarily confined to these planes during steady-state creep unless they are pinned by interstitials.
Axial offset anomaly (AOA) is caused by the deposition of crud on the fuel cladding of a PWR. When significant levels of crud build up on the cladding, boron can accumulate in the pores of the crud as a concentrated solution or solid phase, and cause the flux depression. Numerous studies have been conducted on the primary water chemistry to reduce the amount of crud in the primary circuit to avoid radioactivity buildup and unexpected power transition in the plant. However, experiments on the crud are restricted in the laboratory because the crud is a highly radioactive material. The objective of this study is to develop a test method for simulating the deposition of crud in a nuclear power plant
The effect of heat transfer is described from heat exchange tubes of a horizontal steam generator on the distribution of primary water to the individual tubes of the tube bundle. It is shown that in a broad interval of mass flow rates and lengths of heat exchange tubes, the simplified method of calcualtion, i.e., calculation of the distribution of primary water into heat exchange tubes neqlecting the changes of physical properties of water along the heat exchange tubes, will yield sufficiently accurate results.
The effect of heat transfer is described from heat exchange tubes of a horizontal steam generator on the distribution of primary water to the individual tubes of the tube bundle. It is shown that in a broad interval of mass flow rates and lengths of heat exchange tubes, the simplified method of calcualtion, i.e., calculation of the distribution of primary water into heat exchange tubes neqlecting the changes of physical properties of water along the heat exchange tubes, will yield sufficiently accurate results. (author).
Primary B-cell lymphoma of thymus is uncommon. We describe the case of a 23-year-old woman with a history of shortness of breath and distended neck veins of 1-month duration. A chest roentgenogram and computed tomographic chest scan of the showed a large anterior mediastinal mass. Tru-cut biopsy revealed primary B-cell lymphoma of thymus. She underwent chemotherapy with no symptomatic improvement. Post-chemotherapy computed tomographic scan of the chest showed no appreciable reduction in tumor size. Surgical excision was carried out with excellent results.
This article introduces the actual artistic state in energy performance terns of the primary aluminium production in Brazil and in the world. Besides, it is evaluated the future evolution perspectives of the electrical specific consumption in the industrial sector, due to the technological innovation and determined capacity eventual expansions in the productive process. 6 refs., 2 figs, 4 tabs
To improve the detection rate of lung cancer, we have introduced low-dose CT and CR technique into a population-based annual mass screening. From December 1999, 3868 and 12618 individuals participated in this screening program with CT and with CR, respectively. Primary lung cancer was detected in 15 (0.39%) by CT and 8 (0.06%) by CR. This results show high detection rate of primary lung cancer as had been previously reported. (author)
Object: To limit the discharge amount of reactor water in a primary system at the time of scram to prevent excessive outflow of reactor water outside the system. Structure: A signal from an upper limit position indicator detects the fact that control rods are completely inserted when the reactor is urgently stopped and the detection signal causes a valve in an outflow line of the discharge water from a control rod driving mechanism to be closed to limit the amount of discharge flown into the scram discharge vessel, thus preventing outflow of reactor water in the primary system after the scram has been initiated. (Kamimura, M.).
A dual fuel engine control system for controlling the power output of a dual fuel compression ignition engine. The engine includes mixing means for combining an oxidizer and a primary fuel at a substantially constant ratio of oxidizer to primary fuel. The power output of the engine is controlled through the use of a throttle valve controlling the quantity of combustible mixture delivered to the combustion chamber. The fuel control system minimizes the quantity of ignition fuel required by controlling the quantity of combustible mixture rather than the fuel of air ratio. (author) figs.
A primary goal of noninvasive studies of human vision is to identify and characterize multiple visual areas in the human brain analogous to those identified in studies of nonhuman primates. By combining functional MEG measurements with images of individual anatomy derived from MRI, the authors hope to determine the location and arrangement of multiple visual areas in human cortex and to probe their functional significance. The authors have identified several different visual areas thus far which appear to be topographically organized. This paper focuses on the retinotopic characterization of the primary visual area (V1) in humans.
To improve operational safety of the fuel channel for Wolsung units the recommended primary heat transport system (PHTS) operating guidelines were developed, which provides a safe operation window in terms of pressure and temperature to maintain fuel channel integrity, which is similar to pressure-temperature curves used for primary pressure boundary integrity in PWRs and deterministic Leak-Before Break (LBB) analyses were conducted using recent understanding of delayed hydride cracking (DHC) mechanism. In addition, a comparative assessment of LBB analysis was made using the procedures of Fitness For Service Guidelines(FFSG) for pressure tubes rev. 0 and rev. 1.
The general objective of the International Seminars of Horizontal Steam Generator Modelling has been the improvement in understanding of realistic thermal hydraulic behaviour of the generators when performing safety analyses for VVER reactors. The main topics presented in the fourth seminar were: thermal hydraulic experiments and analyses, primary collector integrity, feedwater distributor replacement, management of primary-to-secondary leakage accidents and new developments in the VVER safety technology. The number of participants, representing designers and manufacturers of the horizontal steam generators, plant operators, engineering companies, research organizations, universities and regulatory authorities, was 70 from 10 countries.
Purpose: In a case of automatically controlling the water level at the time of generating a lower power, to impact the followability of the control necessary for the power variation of the steam generator thereby to obtain good controllability. Constitution: A signal of deviation of water level of a steam generator and its set value and a signal of a difference between the temperature of the primary coolant in the high temperature side pipeline and that of the primary coolant in the low temperature side pipeline are used to automatically or manually control the flow quantity of water fed to the steam generator. (Yoshihara, H.).
Plans, engineering parameters, and some test results for several FFTF core and primary sodium circuit instrument systems are presented. The systems discussed include temperature, flow, pressure, leak detectors, level sensors, fuel failure monitoring, sodium impurity analysis and cover gas monitors. Since many of these instruments are similar to those used in other fast reactors around the world, only a brief description is presented for these systems. Results of recent demonstration tests of the FFTF Under-Sodium Viewing and Ranging system are also presented. (U.K.).
The sensitivity of the primary circuit material was examined at the Mochovce and Dukovany NPPs. No significant sensitivity of the base material or the weld metal to the initiation of corrosion cracking was observed. Thermal aging was found to accelerate significantly the corrosion fatigue kinetics in the material of the heat affected zone. The threshold values of the double amplitudes of the stress intensity factor were below 8 MPa/m"2 for the materials examined, with a cycle asymmetry coefficient of 0.65. The tests revealed no appreciable sensitivity to general corrosion, pitting, or intergranular corrosion. (J.B.). 7 tabs., 26 figs., 11 refs.
Corrosion is increasingly becoming an important factor reducing the reliability of many nuclear power plant components. The significance is evaluated of corrosion phenomena with respect to the reliability of primary circuit components of LWR's, viz., the reactor pressure vessel, primary piping, steam generator, and fuel elements. The mechanism of corrosion phenomena is explained and methods of minimizing their effects are presented. An analysis is made of the needs to solve the corrosion problems of nuclear power plants from the point of view of Czechoslovak producers and research and development activities. International cooperation is reviewed and main problems are formulated on which the solution of corrosion problems of structural materials used in WWER type nuclear power plants should be focussed. (author).
The purpose of this work was to develop and evaluate a method of locating breached fuel within the Fast Flux Test Facility (FFTF) reactor based on the relative response of the delayed neutron monitors (DNM) located on each of the three primary sodium cooling loops. The primary method of location is the use of tag gas containing unique ratios of the noble gases xenon and krypton. Although the tag gas system works quite well, it is relatively expensive because of the costs of preparing and loading the gas into each fuel pin. Triangulation of DNM signals could potentially decrease tag gas costs while maintaining overall location reliability.
This is a retrospective analysis of bone scans in 72 patients with Ewing's sarcoma. Sites of primary disease were found to be evenly distributed among the axial skeleton and the proximal and distal extremities. Primary disease sites in the axial skeleton were more frequently associated with metastases. Fifty-three of these patients had their first scans done at presentation; among them, 25 were found to have metastases. Unsuspected metastases were picked up in 28 of all the patients. Metastases at presentation were seen to be associated with a poorer prognosis.
In this project we determined primary production and optical variability in the shelf and slope waters off of Cape Hatteras, N.C. These processes were addressed in conjunction with other Ocean Margins Program investigators, during the Spring Transition period and during Summer. We found that there were significant differences in measured parameters between Spring and Summer, enabling us to develop seasonally specific carbon production and ecosystem models as well as seasonal and regional algorithm improvements for use in remote sensing applications.
One of ENEA's many activities consists in dealing with the analysis of information strategies. In this case the analysis concerns an environmental issue, the ozone hole which, in spite of the consideration given by the media, is not sufficiently highlighted, as well as in the case of climate changes issue. A survey of the coverage of four daily newspapers was realized; the time period covered by the analysis spans form January 1996 to December 1997, 77 articles in total. The newspapers involved are: La Repubblica, Il Corriere della Sera, L'Unita' on a national scale, and Il Resto del Carlino on a regional scale. The number of articles analyzed is divided as follows: 26 for the Repubblica, 24 for the Corriere della Sera, 21 for the Unita', 6 for the Resto del Carlino. The purpose of the work was to detect quality and quantity indicators of the Italian press about the ozone hole issue and possible environmental risks conveyed to ...
Environmental factors, phytoplankton biomass (Chl a) and primary production of two water areas in Daya Bay (Dapeng'ao Bay and Aotou Bay) were investigated during the transition period from spring to summer. Chl a ranged from 3.20 to 13.62 and 13.43 to 26.49 mg m"-"3 in Dapeng'ao Bay and Aotou Bay respectively, if data obtained during red tides are excluded. Primary production varied between 239.7 and 1001.4 mgC m"-"2 d"-"1 in Dapeng'ao Bay. The regional distribution of Chl a and primary production were mostly consistent from spring to summer in both bays. Seasonal transition characters have been found in Daya Bay from spring to summer, including high values of DO, nitrate and silicate. Size structures of phytoplankton and its primary production do not change very much from spring to summer, with micro-phytoplankton dominating and contributing about 50% of the whole. In Daya Bay, phytoplankton is limited ...
The forest products industry is the third largest economic sector in Alberta, producing pulp and paper, dimensional lumber, paneling, and value added products, providing some 40,000 jobs . 'Value added' is a key component of expanding economic activity within the forest products sector. Wood residues can play a key role in obtaining more value from forest resources by providing new products, serving as feedstock to energy and chemical production, and playing a role in agriculture and land reclamation. One of the principal roles of the Forest Products Development Branch of the Alberta Economics Department is to encourage the development of the industry by creating new uses for these materials and developing awareness of the scope of the resource. Distances to markets, economic competition from conventional energy sources and coordination of research efforts are substantial barriers to further development that the Forest Products Development Branch has to face ...
Previous studies have found that classrooms are often inadequately ventilated, with the resultant increased risk of negative impacts on the pupils. This paper describes a series of field measurements that investigated the indoor air quality, thermal comfort and acoustic performance of nine recently built secondary schools in England. The most significant conclusion is that the complex interaction between ventilation, thermal comfort and acoustics presents considerable challenges for designers. The study showed that while the acoustic standards are demanding it was possible to achieve natural ventilation designs that met the criteria for indoor ambient noise levels when external noise levels were not excessive. Most classrooms in the sample met the requirement of limiting the daily average CO{sub 2} concentration to below 1500 ppm but just a few met the need to readily provide 8 l/s per person of fresh air under the easy control of the occupants. It would seem that ...
The performance of a group of reference laboratories measuring lead in blood, has been monitored by an intensive external quality assessment programme, since 1974. Performance was similar to that observed in other, larger quality control surveys but rapidly improved following detailed investigations of critical factors in the analytical methodology. The introduction of a rigorous internal quality control protocol, with all laboratories using the same well-characterised materials, has produced external quality control results that are both accurate and very tightly distributed. Between-laboratory coefficients of variation of less than 5%, less than 6% and less than 20% are now obtained at concentrations of over 1.0 ..mu..mol/l (20.7 ..mu..g/dl), 0.5-1.0 ..mu..mol/l (10-20 ..mu..g/dl) and less than 0.5 ..mu..mol/l (10 ..mu..g/dl), respectively. These results represent the best that can be achieved by current methodology and instrumentation in regular, daily use.
Urinary tract infection (UTI) is a common problem in the female population. Women with diabetes mellitus are possibly at a higher risk. The usual medical therapy for UTI is antibiotic treatment. The aim of this study is to explore strategies employed by diabetic women for prevention and self-treatment of UTI. Forty-two women with diabetes mellitus who had experienced at least one episode of UTI in the last six months were included. Data collection included background information, questions about prevention and self-treatment strategies and a clinical examination to measure maximal urine flow, residual urine, a blood test evaluating diabetic control (HbA1c) and a urine test strip for determination of glucose, leucocytes, nitrite, blood, protein and pH. Thirty-five participants (83.3%) reported changes in daily routines like 'always keeping warm', 'increased fluid intake', 'good personal hygiene' as prevention strategies. Different herb and plant extracts were used ...
Tumor necrosis factor alpha (TNF-alpha) and interleukin-1 (IL-1) have been shown to stimulate bone resorption in vitro. We have now investigated whether these cytokines also cause a similar action when administered in vivo. This was made possible by the adaptation of a newly developed technique that enables the continual assessment of bone resorption in vivo in mice by measuring urinary excretion of {sup 3}H from ({sup 3}H)tetracycline-prelabeled animals. Experiments using maneuvers known to influence bone resorption, such as a change in dietary calcium or administration of parathyroid hormone or dichloromethylenebisphosphonate, indicate that the technique is reliable and sensitive in mice. Daily intravenous administration of either recombinant human or recombinant murine TNF-alpha, as well as subcutaneous administration of recombinant human IL-1 alpha, were found to stimulate bone resorption in a dose-dependent manner. The effect was maximal within 2 days. Thus, ...
Due to the fact that, the workers' behavior is characterized by its complexity and diversity, this issue has been seen as a great 'black box' in discussions regarding the Management Systems of SHE. Associated with this issue other arises: How conscious people? How to engage them with the process? How to improve the risk control? How to motivate the prevention? Most of these responses are discussed in the Social and Human Sciences for many years. However, it is necessary to closer the technical-operational knowledge and the human aspects, applying in the organizations' daily work, to make the working environment more safe. The purpose of this study, therefore, is examining the possibility of reducing accidents through the identification and treatment of deviations (unsafe acts and unsafe conditions), cause the whole accident, be it serious or not, begins with a small deviation. It was used as a reference tool, the Behavior audit ...
The level of assimilation of dietary iron is believed to have an important influence on iron status. To examine the effect of enhancing the availability of dietary iron on iron balance, 17 adult volunteer subjects were given 2 g of ascorbic acid daily with meals for 16 weeks. Serum ferritin levels before and after the study averaged 46 and 43 micrograms/L, respectively, indicating a negligible effect on iron stores. When vitamin C supplementation was continued for an additional 20 months in five iron-replete and four iron-deficient subjects, serum ferritin determinations again failed to indicate any significant effect of the vitamin C on iron reserves. These findings were not explained by intestinal adaptation to the enhancing effect of the vitamin, because radioisotopic measurements of nonheme iron absorption showed no reduction in the enhancing effect of 1 g of ascorbic acid after four months of megadoses of vitamin C. It is concluded that altering the ...
Vaarst Vestervang (Denmark) comprises 16 villas and 1 communal building. The complex was designed by the inhabitants themselves with the aim of polluting the environment as little as possible. The land area constitutes 69.000 square meters where it is possible to grass animals. The document reports a measuring programme concerning the overall heat consumption as one of the main aims of the inhabitants is to save energy and thus contribute to the protection of the environment. The capacity of the solar collectors predominantly used in the building complex was 235 kWh/m{sup 2}. Supplementary heating is provided by boilers fired with wood. The measuring system is described in detail. Tables show the influence of heat transmission losses, ventilation, airing out of rooms, the angle of the sun`s rays within the buildings and heating needs on energy consumption. Energy consumption data is presented in relation to the forms of space and water heating utilized. Daily ...
This book describes one approach to building and operating biogas systems. The biogas systems include raw material preparation, digesters, separate gas storage tanks, use of the gas to run engines, and the use of the sludge as fertilizer. Chapters included are: (1) "Introduction"; (2) "Biogas Systems are Small Factories"; (3) "The Raw Materials of Biogas Digestion"; (4) "The Daily Operation of a Biogas Factory"; (5) "The Once a Year Cleaning of the Digester"; (6) "Tanks and Pipes: Storing and Moving Biogas"; (7) "The Factory's Products: Biogas"; (8) "The Factory's Products: Biofertilizer"; (9) "The ABCs of Safety"; and (10) "Conclusion: Profiting from an Appropriate Technology." Many diagrams are provided throughout this handbook. New ideas, composting, bioinsecticides, ferrocement, facts and figures, sources and resources, feasibility studies, problem solving, and vocabulary are presented in the appendices. (YP)
The aims of the study were to develop and test the psychometric properties of the Thai Family Health Routines (TFHR) scale, a 70-item self-report questionnaire used to measure the health of Thai families through their routine behaviors in daily life. Development of the TFHR was based on the structural domains of Denham's Family Health Model. The TFHR scale was initially composed of 85 items and tested on 1,040 families living in the central region of Thailand. The confirmatory factor analysis, with an acceptable factor structure model, yielded 70 items aligned with six factors: self-care, safety and prevention, mental health behavior, family care, family caregiving, and illness care routines. The preliminary psychometric properties demonstrated that the TFHR scale had satisfactory internal consistency, criterion validity, and construct validity. The test results suggested that the TFHR scale has potential benefits for family and community nurses to assess Thai ...
Bone-seeking radiopharmaceutical uptake (BSRU) was used to examine alveolar bone metabolism in a longitudinal study of tetracycline efficacy in beagle dogs. BSRU was measured in untreated control dogs and in beagles receiving either 250 mg or 500 mg oral tetracycline-HCl daily for 16 months. The rate of bone loss was determined for radiographs taken semiannually for a 6-month pretreatment period and for a 24-month treatment period. Measurements of BSRU obtained at month 16 of treatment were correlated with rates of bone loss determined radiographically in an attempt to determine whether BSRU was indicative of the subsequent rate of bone loss. A reduced rate of alveolar bone loss was found in the 500 mg tetracycline group at month 16 of the study relative to the untreated controls which was consistent with the decreased bone-seeking radiopharmaceutical uptake observed in this group. A significantly increased BSRU (p<.0001) was found in the 250 mg tetracycline ...
Lutein is a yellow pigment found in common foods that promotes the health of eyes and skin and is associated with reduced risk of age-related macular degeneration and cataracts. In the present study, selected high-lutein wheat and corn were milled into wholegrain flours by two mills to improve flour uniformity. The high-lutein and lutein-fortified wholegrain flours were processed into breads, cookies, and muffins to study lutein stability during baking and subsequent storage. Lutein and its isomers were separated, identified, and quantified by LC-UV/vis and LC-MS following extraction with water-saturated 1-butanol. Baking resulted in a significant reduction in all-trans-lutein and the formation of cis-lutein and cis-zeaxanthin isomers. Subsequent storage at ambient temperature had a slight impact on the content of all-trans-lutein. Effects of processing were more pronounced in lutein-fortified products, and the degradation rate of lutein was influenced by concentration and baking ...
Kaiser Alumina and Chemical Co. impounds red mud, the byproduct of alumina production, behind levees. Kaiser recognizes that this action cannot be maintained indefinitely. Therefore, a project is in progress to produce useful products from red mud that increase the profitability of the Gramercy facility. Before products could be developed, an obstacle had to be overcome. The annual rainfall in South Louisiana prevents evaporative drying of the mud lakes. Innovative methods were applied to dry the lake mud. Two products have been developed. A daily landfill cover and an absorbant, which are marketed under the Cajunite{trademark} banner. Both products are currently being tested by potential customers at their sites. Environmental concerns were addressed during development. Extensive TCLP results show no metal leachate problems. All pilot tests and plant trials received LADEQ approval. Products that are under development include levee core, road base, fertilizer ...
The radioprotective effects of Liv.52 on tissue-reduced glutathione (GSH) levels were studied in rats. Adult female Sprague Dawley rats were exposed to whole body gamma radiation of 4 Gy and 8 Gy. Prior to radiation exposure, Liv.52 was fed, one ml per rat, daily for 15 days. Three days after radiation exposure, reduced glutathione levels in the liver, spleen, kidney and blood were studied. Liv.52 was beneficial in restoring the spleen weight to body weigh t ratio in the animals of the 4 Gy group. In the spleen and liver, Liv.52 helped to restore reduced glutathione in sub-lethally exposed rats. Blood-reduced glutathione was found to be normal in both groups of experimental rats who received Liv.52. The above results exhibit the radioprotective effects of Liv.52 in relation to tissue-reduced glutathione in experimental rats exposed to sub-lethal doses of radiation. (author). 3 tabs., 25 refs.
RADIANT{trademark} is manufactured by United States Surgical Corporation, Vascular Therapies Division, (formerly Progressive Angioplasty Systems). The system comprises a liquid {beta}-radiation source, a shielded isolation/transfer device (ISAT), modified over-the-wire or rapid exchange delivery balloons, and accessory kits. The liquid {beta}-source is Rhenium-188 in the form of sodium perrhenate (NaReO{sub 4}), Rhenium-188 is primarily a {beta}-emitter with a physical half-life of 17.0 hours. The maximum energy of the {beta}-particles is 2.1 MeV. The source is produced daily in the nuclear pharmacy hot lab by eluting a Tungsten-188/Rhenium-188 generator manufactured by Oak Ridge National Laboratory (ORNL). Using anion exchange columns and Millipore filters the effluent is concentrated to approximately 100 mCi/ml, calibrated, and loaded into the (ISAT) which is subsequently transported to the cardiac catheterization laboratory. The delivery catheters are modified ...
Erectile dysfunction following radical prostatectomy remains a frequent problem despite the development of nerve-sparing techniques. This erectile dysfunction is believed to be neurogenic, enhanced by hypoxia-induced structural changes which result in additional veno-occlusive dysfunction. Recently, daily use of intracavernous vasoactive substances and oral use of PDE5-inhibitors have been clinically studied for treatment of postprostatectomy erectile dysfunction. Since these studies showed benefits of "penile rehabilitation therapy," these effects have been studied in a preclinical setting. We reviewed experimental literature on erectile tissue preserving and neuroregenerative treatment strategies, and found that preservation of the erectile tissue by the use of intracavernous nitric oxide donors or vasoactive substances, oral PDE5-inhibitors, and hyperbaric oxygen therapy improved erectile function by antifibrotic effects and preservation of smooth muscle. ...
This presentation gives the results of a research programme aimed at evaluating exhaust emissions from ships moving within confined coastal zones, as in Piraeus harbour. The level of various exhaust emissions were estimated on the basis of a mathematical model applied for each sea traffic element (ship). Hourly and daily records of all ships` movements in different parts of the harbour were compiled, covering extended periods of time and associated with different shipping operational characteristics (peaks, lows, etc). In order to correlate the exhaust emissions from shipping with the quality of the air in the area of interest, land-based measurements for the same pollutants were carried out in selected locations, near the port and in the greater Athens area. This enabled the investigation of time and spatial diffusion of exhaust emissions from shipping within the area of interest, taking into account the influence of prevailing meteorological conditions. A close ...
In this paper we present results of our investigation into the relationship between urban microclimate and the local density of tree cover as measured in Sacramento, California. These results were obtained through analysis of data collected in a two-month long monitoring program with automatic weather stations installed at 15 residential locations throughout the city. Measured wind speeds showed a highly negative correlation with respect to tree cover. Daily peak air temperatures showed significant variation often differing from site to site by 2 to 4{degrees}C ({approx}3.5 to 7{degrees}F). A complex interaction between several competing factors is discussed leading to the conclusion that additional tree cover may actually increase urban air temperatures on synoptically cool days. It is suggested that this does not have a significant adverse affect in terms of overall summer urban cooling load. This is supported by an integrated analysis of the temperature data ...
Nike is a recently completed multi-kilojoule krypton fluoride (KrF) laser that has been built to study the physics of direct drive inertial confinement fusion. This paper describes in detail both the pulsed power and optical performance of the largest amplifier in the Nike laser, the 60 cm amplifier. This is a double pass, double sided, electron beam-pumped system that amplifies the laser beam from an input of 50 J to an output of up to 5 kJ. It has an optical aperture of 60 cm x 60 cm and a gain length of 200 cm. The two electron beams are 60 cm high x 200 cm wide, have a voltage of 640 kV, a current of 540 kA, and a flat top power pulse duration of 250 ns. A 2 kG magnetic field is used to guide the beams and prevent self-pinching. Each electron beam is produced by its own Marx/pulse forming line system. The amplifier has been fully integrated into the Nike system and is used on a daily basis for laser-target experiments. copyright 1997 American Institute of ...
Studies were undertaken to examine the effects of animal age on the anticarcinogenic properties of antioxidants. Female hairless mice, 2.5, 4.5 and 9.5 months of age, were subjected to daily irradiation from Westinghouse BZS-WLG lamps for 19 weeks. Experimental groups of animals were maintained on a commercial rodent meal supplemented with a 2% (w/w) antioxidant mixture. Control groups received only the meal. Tumour latency, expressed as median time to tumor development, was significantly greater for all age groups receiving antioxidants than for their similarly aged controls. However, the response to antioxidants appeared to decrease with age and the antioxidant effect was significantly less in the 9.5 month-old group than in the 2.5 month-old group. Likewise, the two youngest groups receiving antioxidants demonstrated a significantly fewer number of tumors per animal. It is concluded that animal age influences the degree of photoprotection provided by ...
Emergency response preparedness for radiological accidents involving wound contamination has become more important, considering the current extending tendency in the nuclear industry related to the nuclear fuel cycle. The US National Council on Radiation Protection and Measurements (NCRP) proposed a biokinetic and dosimetric model for the intake of radionuclides through contaminated wounds in 2007. The present paper describes the implementation of this NCRP wound model for the prediction of systemic behaviour of some important radioactive elements encountered in workplaces related to the nuclear industry. The NCRP wound model was linked to the current ICRP systemic model at each blood compartment and simultaneous differential equations for the content of radioactivity in each compartment and excreta were solved with the Runge-Kutta method. The results of the calculation of wound, whole-body or specific organ retention and daily urinary or faecal excretion rate of ...
Establishment of a continuous population has been prevented over a 24 year period in the San Joaquin Valley, USA, through continuous, daily in-season release of sterile pink bollworms based on an extensive trap monitoring programme. A post-harvest crop destruction ordinance and occasional use of pheromones as disruptants were the only other factors used by programme management, except in 1990. In 1990, the programme used a conventional insecticide on 280 acres (113 ha) out of 1.18 million acres (477,546 ha) of cotton. During the four year period 1986-1989, a management system was explored using a high rate pheromone disruption system and sterile insects. Major reductions in conventional insecticide usage, while maintaining extremely low populations, were evident in this semi-isolated valley of southern California. It is hoped that this will provide a model for a future large scale test on up to 20,000 acres (8100 ha) of cotton. (author). 11 refs, 1 fig., 7 tabs.
Introduction: We have evaluated the ability of a semi-automated, optomotor reflex method to assess drug-induced visual dysfunction, in albino and pigmented rats and mice. Methods: Male Han Wistar (HW) and Long Evans (LE) rats and mice (CD-1 and C57BL/6) were tested in a chamber formed by 4 computer monitors displaying a rotating vertical grating, to elicit head-tracking movements. The highest visible grating frequency was taken as the threshold of visual acuity, in cycles per degree (c/d). Animals received an intravenous infusion of either sodium iodate (50mg/kg) or 0.9% w/v NaCl (aq). They were tested 2h later, then re-tested daily for a further 3days. The time course of the effect was assessed in HW rats over a 6-week period, including electron microscopy, and immunohistochemical analysi...
Energy study was conducted in an organic fertilizer production plant in Nigeria, to determine the energy consumption patterns and the associated costs for the production of both powdered and pelletised fertilizer. Analysis was conducted for a daily production of 9000 kg of the finished products. Eight and nine defined unit operations were required for production of powder and pellets, respectively. The electrical and manual energy required for the production of powder were 94.5 and 5.6% of the total energy, respectively, with corresponding 93.9 and 5.1% for the production of pellets. The respective average energy intensities were estimated as 0.28 and 0.35 MJ/kg for powder and pellets. The most energy intensive operation was identified as the pulverizing unit with energy intensity of 0.09 MJ/kg, accounting for respective proportions of 33.4 and 27.0% of the total energy for production of powder and pellets. The energy cost per unit production for powdered and ...
Previous work suggests that supplemental ascorbic acid (AA) may inhibit intestinal copper absorption by stabilizing the less absorbable cuprous state. The authors studied copper absorption in healthy men (age 19-32) fed a constant diet with different amounts of ascorbic acid supplements. The 6 men were confined to a metabolic unit for the entire 14 week study. The basal diet consisted of a 7 day rotating menu which provided an average of 2.1 mg Cu/d and was adequate in all other nutrients except AA (5 mg/d). The basal diet was supplemented with either zero, 60, or 600 mg of AA daily, added to grape juice and consumed at each meal. All feces were collected. Blood was taken weekly for monitoring AA and copper status. Copper absorption was determined by both balance and "6"5Cu stable isotope techniques. As determined by fecal Cu excretion, varying intakes of AA between 0.1 to 10 times the RDA had no significant effect on copper retention. This is consistent with the ...
This paper describes the challenges involved in the construction of a mid-rise housing development in Boston, Massachusetts, during which the development team elected to upgrade the initial design criteria from Minimum Building Code to Energy Star and Leadership in Energy and Environmental Design (LEED) certification. The various constraints imposed on the development were discussed, including constraints imposed by the involvement of substantial public funds as well as the constraints imposed by various funding sources that were approached to leverage energy efficiency and green building investment via competitive grant solicitations. Building owner and utility cost management priorities were outlined along with details of central mechanical system selection. Issues concerning isolation and compartmentalization were examined along with indoor pollution source control. A building load analysis was presented as well as details of daily heating and cooling ...
The cost of transporting biogas digestate can be decreased by reducing its water content. However, the digestate emits volatile compounds during drying. This study investigated the drying behaviour and the change of digestate composition. Drying took place in a hybrid solar/waste-heat dryer that used solar energy as well as waste heat from a combined heat and power unit (CHP) and the exhaust air of a microturbine. The experiment involved the use of 60 t of liquid digestate. Climatic conditions were measured inside and outside the drying hall. Dry matter (DM) and organic dry matter (ODM) were also measured on a daily basis. In addition, the energy consumption of waste and solar heat were recorded and related to the quantity of dried feedstock. The total nitrogen, ammonium, phosphate, potassium oxide, magnesium oxide and calcium oxide in the digestate were subjected to chemical analysis before and after the drying process. Losses of nitrogen were calculated. Specific ...
The molar of guinea pigs was irradiated with /sup 60/Co-..gamma.. ray for daily observations of the manifestation of disturbed tooth formation by microradiography and the time registration by tetracycline-labelling. Irradiation first injured young blast cells of the dentin in the growth phase, dental pulp cells, and cells of the enamel. The portion composed of injured cells formed a depressed ''constriction'' from the dental pulp side toward the border between the enamel and dentin. The cells of the enamel injured by irradiation in the growth phase later formed a very thin irregular stroma. In contrast, cells in the differentiation or subsequent phase at the time of irradiation and cells probably having started to grow after irradiation proceeded with formation of a normal stroma and calcification. No uniform relation was obtained between the histological staining of the organic stroma of normal or abnormal dentin and ...
The distribution of lead in lactating mice and suckling offspring was studied with whole body autoradiography at 4 and 24 h after a single intravenous injection of {sup 203}Pb (50 mmol Pb/kg) to the dams. In the lactating mice on day 14 of lactation, the highest uptake of radioactivity at 4 h after administration was recorded in renal cortex, skeleton and liver. A high uptake was also evident in the mannary gland. At 24 h after administration, the radioactivity had decreased in most organs except in the skeleton. In the suckling pups, exposed to lead only via dams` milk for 24 h, the highest level of radioactivity was present in the intestinal mucosa and a much lower level of radioactivity was present in the skeleton. The mammary glands from mice given three daily intravenous injections of 240 {mu}mol Pb/kg were examined with X-ray microanalysis. At 4 h after the last injection, lead was found associated with casein micelles both inside the alveolar cell and in the ...
The distribution of lead in lactating mice and suckling offspring was studied with whole body autoradiography at 4 and 24 h after a single intravenous injection of "2"0"3Pb (50 mmol Pb/kg) to the dams. In the lactating mice on day 14 of lactation, the highest uptake of radioactivity at 4 h after administration was recorded in renal cortex, skeleton and liver. A high uptake was also evident in the mannary gland. At 24 h after administration, the radioactivity had decreased in most organs except in the skeleton. In the suckling pups, exposed to lead only via dams' milk for 24 h, the highest level of radioactivity was present in the intestinal mucosa and a much lower level of radioactivity was present in the skeleton. The mammary glands from mice given three daily intravenous injections of 240 #mu#mol Pb/kg were examined with X-ray microanalysis. At 4 h after the last injection, lead was found associated with casein micelles both inside the alveolar cell and in the ...
WR-2721 (S-2-(3-aminopropylamino)ethylphosphorothioic acid) has been demonstrated to be cytotoxic to stem spermatogonia in the mouse. Five and 10 injections of 300 mg/kg killed sufficient numbers of stem cells to reduce sperm production 56 days after treatment by 16 and 43%, respectively. Single injections of 300 or 400 mg/kg of WR-2721 given 15 min after irradiation produced negligible toxicity to stem cells as measured by counts of repopulated tubules; 600 mg/kg reduced stem cell survival by 47%. Four daily injections of 300 mg/kg given 4, 3, 2, and 1 days prior to irradiation reduced stem cell survival by about 60%. The cytotoxic effects of WR-2721 on testicular stem cells at least partially explains the reduced protection factors observed in the testis with low doses of radiation and during fractionated treatments involving multiple injections of drug.
Energy expenditure (EE) of four adult men on a weight-maintenance diet was estimated by use of doubly labeled water, intake balance, and direct and indirect calorimetry. The doubly labeled water (2H218O) method was used to estimate free-living EE for 13 d. Metabolizable energy (ME) intake was used to estimate free-living EE for 1 wk. The subjects' 24-h EE was measured in a dual direct-indirect room calorimeter on 3 alternate days. Estimates of free-living EE as measured by ME intake and doubly labeled water indicate agreement between the two methods (mean difference +/- SEM, -1.04 +/- 0.63%). Measurements of EE with indirect and direct calorimetry are equivalent (mean difference 0.63 +/- 0.44%). The daily EE measured by doubly labeled water in these free-living adults over a 13-d period was 15.01% greater than the 24-h EE measured within the calorimeter.
Therapeutic effect of p-aminobenzoic acid-N-xyloside Na (K-247) were studied. Eleven patients with a variety of solid tumors were treated with K-247 alone. K-247 was given orally 800 mg daily for 4 weeks. As for side effect of the drug, only mild gastritis was observed in a few patients. Partial response (over 25% reduction of tumor size) with a median duration of two months was observed in 3 patients. These cases were metastatic tumor of lung from the carcinoma of thyroid, metastatic tumors of lung from the carcinoma of kidney, and mediastinal tumor. In eight patients the response was classified as no change and in one patient there was progressive disease. Thus K-247 has some therapeutic activity in patients with solid tumor. Combination therapy of irradiation and administration of K-247 were also studied. In the twelve patients receiving the combination therapy, partial response was observed in 7 patients with complete response in 3 patients. In some patients it ...
The ruptured offshore oil well 80 miles from Mexican town of Ciudad del Carmen, which poured 8000 barrels of light oil a day into the Gulf of Mexico, provided marine scientists with the opportunity to monitor the spill and see what happens to petroleum hydrocarbons in sea water. Scientists followed changes in viscosity, surface tension, and buoyancy of individual oil globs as they moved through the water and interacted with the surface slick. Using gas chromatography and mass spectroscopy, chemists are gaining an understanding of the unique characteristics of the oil. Computer-generated models projected the slick's movement in the Gulf in response to wind and wave pressures, but the sophisticated system did not give an accurate daily prediction. Immediate damage to fish, turtles, and sea birds was documented by tagging. Long-term effects will take longer to ascertain since 25 years is generally required to flush oil out of sediments. Fishermen do not agree ...
The stability of a solid ice cover subjected to rapidly varying water levels and discharge was investigated. The support from the bank limits the stress in the ice cover and consequently bank contact must be maintained to ensure ice cover stability. An analysis was required of the stability of ice hinges, a flexible connection between a solid ice cover and the riverbank. Phase II and phase III of the research involved a field study of the Peace River, investigating the evolution of ice hinges with water level variation, from initial ice cover cracking parallel to the banks, to a fully developed hinge. A test program of midwinter discharge variations was undertaken to gather specific data and measurements of ice hinge link length, ice thickness, hinge joint behavior, riverbank geometry, and response of ice hinging to water level variation. This volume of appendices to the study presents detailed observations and comments from field notes through the formation, midwinter and breakup ...
The stability of a solid ice cover subjected to rapidly varying water levels and discharge was investigated. The support from the bank limits the stress in the ice cover and consequently bank contact must be maintained to ensure ice cover stability. An analysis was required of the stability of ice hinges, a flexible connection between a solid ice cover and the riverbank. Phase II and phase III of the research involved a field study of the Peace River, investigating the evolution of ice hinges with water level variation, from initial ice cover cracking parallel to the banks, to a fully developed hinge. A test program of midwinter discharge variations was undertaken to gather specific data and measurements of ice hinge link length, ice thickness, hinge joint behavior, riverbank geometry, and response of ice hinging to water level variation. As a result of the program, concepts developed throughout the study were confirmed, preliminary guidelines for hydroelectric power plant operation at ...
Summary Potential predictors of egg quality were assessed in whiting Merlangius merlangus L. permitted to spawn in a tank from which eggs were collected. These included fertilisation rate, the proportion of viable buoyant eggs, egg diameter, and egg wet and dry weights; all were influenced by temporal effects and were negatively correlated with days from start of spawning. The spawning period was protracted, from February to June. Mean daily egg production per female was 2.74 +- 2.43 g and 2338 +- 2075 eggs, equivalent to 14.6 +- 13.1 g kg-1 day-1 female-1. Egg diameter was 1.21 +- 0.04 mm, egg wet weight 1.20 +- 0.21 mg, dry weight 0.10 +- 0.02 mg, and mean fertilisation rate and hatching rates were 76.8 and 73.3%, respectively. The incubation period ranged from 72 to 80 degree days and w...
This research centered on finding and perfecting methods of collection and disposal of refuse in Ibadan North Local Government Areas. The methodology used included questionnaire administration, personal interviews, field reconnaissance, and biochemical tests of water samples, all aimed at providing useful data for the design of effective methods of collecting and disposing refuse. The local government area was divided into three classes based on resident income: a high-income area (Bodija Avenue, etc.), a medium-income area (Sanngo, Oluyole, etc.), and a low-income area (Beere, Adeoyo, etc.). The research outcomes revealed that the waste generation rate for the local government ranged from 0.2 to 0.33 kg/cap/day and waste density ranged from 172.41 to 217.61 kg/m"3. Water analyses showed that the chloride, manganese, lead, and cadmium levels in water from low-income areas were above the WHO standard. The refuse generated in high and medium-income areas was collected and transported to ...