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No abstract available.

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Two complementary computer programs have been developed for forecasting the demands and evaluating the costs of proposed radiographic facilities. The models are employed here in analyses of the sensitivity...Full Text Available

International Nuclear Information System (INIS)

1975. USSR Zabrodskij, VA Nedavnij, SN INIS-mf--3677. Available from

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... biologically important compounds is sharply lowered with passage of the solutions to the cell an organ, where their sensitivity ...

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society organisations (more than 30) in reaching the most vulnerable groups and dealing with a subject area as sensitive

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An unsymmetrical squaraine dye which contains an arylamino group was synthesized and used in dye-sensitized solar cells. The molar extinction coefficient of the dye is 77793 M-1 cm-1. Because our synthesized molecule may have no diradical character or the contribution of the diradicaloid component to resonance is quite small, the newly designed squaraine dye has a maximum absorption at 546 nm in the visible region compared with the NIR squaraine sensitizers. Cyclic voltammetry and time dependent density function theory calculation were accomplished to scrutinize the sensitized performance of the dye. Meanwhile, the novel sensitizer has been used to sensitize nanocrystalline TiO2-based solar cell. Under standard global AM 1.5 solar conditions, the squaraine dye-sensitized cell gives a short...

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BackgroundChanges in ionic concentration have a fundamental effect on numerous physiological processes. For example, IP₃-gated thapsigargin sensitive intracellular calcium...Full Text Available

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Purpose: This paper reviews and reassesses the internationally accepted niches or ‘targets’ in bone marrow that are sensitive to the induction of leukaemia and primary...Full Text Available

UK PubMed Central (United Kingdom)

G-protein-coupled receptor signalling has been suggested to be voltage dependent in a number of cell types; however, the limits of sensitivity of this potentially important phenomenon are unknown. Using...Full Text Available

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PurposeTo assess the relationship between low-grade inflammation, measured as basal high sensitivity (hs)-CRP, and IVF outcome.MethodsWe recruited...Full Text Available

UK PubMed Central (United Kingdom)

Increased sensitivity to light-induced melatonin suppression characterizes some, but not all, patients with bipolar illness or seasonal affective disorder. The aim of this study was to test...Full Text Available

UK PubMed Central (United Kingdom)

Not all detectable differences between face images correspond to a change in identity. Here we measure both sensitivity to change and the criterion difference that is perceived as a change in identity....Full Text Available

UK PubMed Central (United Kingdom)

1. Sensory fibres innervate the adrenal medulla but their function is not known. In this paper we have studied the effect of capsaicin-sensitive sensory fibres on the adrenal catecholamine (CA) response...Full Text Available

UK PubMed Central (United Kingdom)

PurposeTo establish normative values for macular light sensitivity and to determine the intrasession fluctuation of perimetric responses using the OPKO/OTI microperimeter.Full Text Available

UK PubMed Central (United Kingdom)

The sensitivities to cefuroxime and cephradine of potentially pathogenic bacteria isolated in two British general hospitals comprising 900 beds have been assessed. In a three-month period 2537 strains...Full Text Available

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Seven mutants of Escherichia coli were isolated that are sensitive to methyl methane sulfonate but not to UV light. They exhibited decreased host cell reactivation capacity for methyl methane sulfonate-treated...Full Text Available

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Detection and quantification of prion infectivity is a crucial step for various fundamental and applied aspects of prion research. Identification of cell lines highly sensitive to prion infection led...Full Text Available

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... sensitive and classified US Government information, a notable recent example being the unlawful release of classified US documents by WikiLeaks ...

Science.gov (United States)

... significant change of spontaneous radiation intensity. It is very sensitive technique allowing the observation of small changes of light absorption. ...

International Nuclear Information System (INIS)

... Industry, Material Science Research Laboratory, Yokosuka, Kanagawa (Japan)

International Nuclear Information System (INIS)

(1978). United States Quan, B. Becker, M. Harris, DR Rensselaer Polytechnic

KoreaScience (Korea)

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International Nuclear Information System (INIS)

Comparison of the embryolethality of monomeric "2"3"9Pu injected at 9 days of gestation demonstrated that the sensitivity of Charles River CD strain was greater than that of Hilltop Wistar rats. Subsequent comparisons showed that rats derived from the Hilltop Fischer strain were more sensitive than the Wistar and, although not directly compared, more sensitive than the CD.

International Nuclear Information System (INIS)

The efficiency of electric power generation by dye-sensitized mesoscopic photovoltaic cells has been progressing steadily over the last years reaching now 11% in full sunlight. An important question for practical applications concerns the stability of these devices under prolonged exposure to light or heat. Strikingly stable operation can be obtained by judicious selection of the sensitizer, electrolyte and sealant rendering feasible a service life of at least 20 years under normal outdoor conditions. The sensitizer playing a central role in the light energy conversion process, we analyze the kinetic requirements for it to sustain the required one hundred million turnovers. We also review recent results on the use of self-assembled monolayers of amphiphilic sensitizers and co-adsorbents to enhance the thermal robustness of the device. (author)

International Nuclear Information System (INIS)

Indoline dye sensitizers were designed and studied theoretically to increase molar extinction coefficients in the visible to near infrared region for solar-cell devices. To gain insight into dye sensitizers' structural, electronic, and optical properties, DFT/TDDFT calculations were performed on a series of dye sensitizers derived from the D149. The good agreement between the experimental and TDDFT calculated absorption spectra of the D149 sensitizer allowed us to provide a detailed assessment of the main spectral features of a series of dye sensitizers. Increase in the conjugation length resulted in a more red-shifted spectral response and less positive oxidation potential than that of the D149. The dye with the dimethylfluorene group showed stronger absorption bands due to a large dipole moment. The calculated dipoles for the dye series correlate well with the observed strong ...

Energy Technology Data Exchange (ETDEWEB)

The U.S. Department of Energy`s (DOE) Environmental Management Office of Science and Technology (EM-50) authorized studies on alternative systems for treating contact-handled DOE mixed low-level radioactive waste (MLLW). The on-going Integrated Thermal Treatment Systems` (ITTS) and the Integrated Nonthermal Treatment Systems` (INTS) studies satisfy this request. EM-50 further authorized supporting studies including this technology and subsystem cost sensitivity analysis. This analysis identifies areas where technology development could have the greatest impact on total life cycle system costs. These areas are determined by evaluating the sensitivity of system life cycle costs relative to changes in life cycle component or phase costs, subsystem costs, contingency allowance, facility capacity, operating life, and disposal costs. For all treatment systems, the most cost sensitive life cycle phase is the operations and ...

Science.gov (United States)

In this study, adjoint sensitivity theory is developed for equations of two-dimensional steady-state flow in a confined aquifer. Both the primary flow equation and the adjoint sensitivity equation are solved using the Galerkin finite element method. The developed computer code is used to investigate the regional flow parameters of the Leadville Formation of the Paradox Basin in Utah and the Wolcamp carbonate/sandstone aquifer of the Palo Duro Basin in the Texas Panhandle. Two performance measures are evaluated, local heads and velocity in the vicinity of potential high-level nuclear waste repositories. The results illustrate the sensitivity of calculated local heads to the boundary conditions. Local velocity-related performance measures are more sensitive to hydraulic conductivities. The uncertainty in the performance measure is a function of the parameter sensitivity, parameter ...

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Yucca Mountain, Nevada is a potential site for a high-level radioactive-waste repository. Uncertainty and sensitivity analyses were performed to estimate critical factors in the performance of the site with respect to a criterion in terms of pre-waste-emplacement ground-water travel time. The degree of failure in the analytical model to meet the criterion is sensitive to the estimate of fracture porosity in the upper welded unit of the problem domain. Fracture porosity is derived from a number of more fundamental measurements including fracture frequency, fracture orientation, and the moisture-retention characteristic inferred for the fracture domain.

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The marine environment is becoming increasingly contaminated by environmental pollutants with the potential to damage DNA, with marine sediments acting as a sink for many of these contaminants. Understanding genotoxic responses in sediment-dwelling marine organisms, such as polychaetes, is therefore of increasing importance. This study is an exploration of species-specific and cell-specific differences in cell sensitivities to DNA-damaging agents in polychaete worms, aimed at increasing fundamental knowledge of their responses to genotoxic damage. The sensitivities of coelomocytes from three polychaetes species of high ecological relevance, i.e. the lugworm Arenicola marina, the harbour ragworm Nereis diversicolor and the king ragworm Nereis virens to genotoxic damage are compared, and dif...

UK PubMed Central (United Kingdom)

BACKGROUNDColorectal cancer (CRC) screening can be administered through tests with varied characteristics and is a preference-sensitive decision.OBJECTIVETo...Full Text Available

International Nuclear Information System (INIS)

... ammonium compounds antigen-antibody reactions hemoglobin inhibition

International Nuclear Information System (INIS)

1998 p. 79 Poland Bandurski, T. Skokowski, J. Mizan-Gross, K. Romanowicz,

UK PubMed Central (United Kingdom)

For some neurotoxic chemicals, neurobehavioral effects are now considered to be among the most sensitive end points yet detected, particularly if exposures occur during critical windows of vulnerability....Full Text Available

UK PubMed Central (United Kingdom)

Direct radiological measurements of the mineral content of femoral bone were performed in 13 patients on maintenance dialysis. They were found to be sufficiently sensitive to be used for monitoring,...Full Text Available

UK PubMed Central (United Kingdom)

All treatments for obesity, including dietary restriction of carbohydrates, have a goal of reducing the storage of fat in adipocytes. The chief enzyme responsible for the mobilization of FFA from adipose...Full Text Available

UK PubMed Central (United Kingdom)

A growing number of environmental toxicants found in pesticides, herbicides, and industrial solvents are believed to have deleterious effects on development by disrupting hormone-sensitive processes....Full Text Available

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Previous studies indicate that the hatching success of brine shrimp (Artemia franciscana) cysts is surprisingly sensitive to ambient metal concentrations. These studies estimated median effective concentrations (EC50s) of 7, 5, and 28??g l?1 for Cd, Cu, and Zn, suggesting that the hatching end point for A. franciscana is the most sensitive tested to date for Cd and Zn in saline environments and comparable in sensitivity with the most sensitive tested to date for Cu. Furthermore, these data suggest that brine shrimp are at significant risk from Cu and Zn in Great Salt Lake (GSL), UT, where ambient concentrations as high as 10 and 14??g l?1, respectively, have been measured. Given that brine shrimp appear to be successfully reproducing in GSL, we hypothesized that these toxicity values were ...

International Nuclear Information System (INIS)

Perfect single-crystal neutron interferometers are adversely sensitive to environmental disturbances, particularly mechanical vibrations. The sensitivity to vibrations results from the slow velocity of thermal neutrons and the long measurement time that are encountered in a typical experiment. Consequently, to achieve a good interference solutions for reducing vibration other than those normally used in optical experiments must be explored. Here we introduce a geometry for a neutron interferometer that is less sensitive to low-frequency vibrations. This design may be compared with both dynamical decoupling methods and decoherence-free subspaces that are described in quantum information processing. By removing the need for bulky vibration isolation setups, this design will make it easier to adopt neutron interferometry to a wide range of applications and increase its sensitivity.

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Purpose To investigate the influence of timolol maleate 0.5% gel-forming solution and brinzolamide 1% ophthalmic suspension on contrast sensitivity, ocular higher-order aberration (HOA), and corneal surface light scattering. Design Prospective, comparative study. Participants Forty normal volunteers were enrolled in this study. Methods We evaluated contrast sensitivity, ocular HOA, and corneal light scattering before and 2, 5, 10, and 15 minutes after instillation of antiglaucoma eyedrops. Contrast sensitivity function was assessed with the CSV-1000RN chart (Vector Vision Co., Greenville, OH). Higher-order aberration was measured for a 4-mm pupil using the Hartmann-Shack aberrometer (KR-9000PW; Topcon, Tokyo, Japan). Corneal surface light scattering was quantitatively evaluated by using th...

UK PubMed Central (United Kingdom)

Chemoreceptors are crucial components in the bacterial sensory systems that mediate chemotaxis. Chemotactic responses exhibit exquisite sensitivity, extensive dynamic range and precise adaptation....Full Text Available

International Nuclear Information System (INIS)

Polish 2001 p. 105 Poland Bogacz, J. Budzanowski, M. Mazur, J. Swakon,

Science.gov (United States)

mulation, with flow quantities stored at the grid vertices. OVERFLOW ..... attack: a separation bubble near the trailing edge of the ..... AGARD CP-429, Jul. 1988. ...

UK PubMed Central (United Kingdom)

We present a technique for identifying the amino acids responsible for a loss of immunoreactivity in response to treating an antigen with a chemical modifier. This is of particular interest...Full Text Available

International Nuclear Information System (INIS)

To analyse the thermal noise of the pendulum mode of a suspended mirror, we interferometrically detect the differential movement of two mirrors suspended as multiple-stage pendulums. We present the set-up of this experiment and the current sensitivity, and also the different steps that we took in the past to increase the sensitivity, which include an auto alignment of the laser beam into the resonator eigenmode, changes of the seismic isolation system to more damping stages and higher moments of inertia and an intensive noise hunting.

International Nuclear Information System (INIS)

A network of second-generation low-temperature gravitational radiation detectors is nearing completion. These detectors, sensitive to mechanical strains of order 10"-"1"8, are possible because of a variety of technical innovations that have been made in cryogenics, low-noise superconducting instrumentation, and vibration isolation techniques. Another five orders of magnitude improvement in energy sensitivity of resonant-mass detectors is possible before the linear amplifier quantum limit is encountered. 33 references, 3 figures, 1 table.

Energy Technology Data Exchange (ETDEWEB)

The NREL Sensitized Solar Cell (SSC) Core Program supports the Solar America Initiative by: (1) targeting new devices and processes for commercialization by 2015 that are less expensive, more efficient, highly reliable, and environmentally benign; (2) collaborating with DOE OS/BES to conduct basic research targeting breakthroughs in key areas, such as ultra-high efficiency and/or ultra-low cost materials and devices.

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This comprehensive, critical review summarizes the use of nanoparticles in enhanced and amplified chemiluminescence detection, illustrated by different reaction strategies, electrogenerated chemiluminescence sensors, immunoassay or hybridization labels and electrogenerated chemiluminescence immunoassay or hybridization sensors. We discuss the analytical applications on the basis of validity, range and sensitivity, and draw some useful conclusions about the most sensitive approach in each type of application.

Science.gov (United States)

The sensitivity and specificity of the MGIT TBc identification (TBc ID) test for Mycobacterium tuberculosis complex (MTC) detection in positive Bactec MGIT cultures were 95.2% and 99.2%, respectively. When MTC-positive results obtained from two additional molecular methods were included, the sensitivity of the MGIT TBc ID test was 85.4%, while that of culture was 95.7%. PMID:21450949

Energy Technology Data Exchange (ETDEWEB)

Design of a beam position monitor (BPM) which is sensitive to low velo charged particle beams is considered. Quantitative estimates are made for the corrections to the conventional approximations to solutions of the Laplace Equation in two-dimensions when a BPM is used to measure to position of low velocity (low-[beta]) beams. (AIP)

UK PubMed Central (United Kingdom)

In clinical situations where a diagnostic real-time PCR assay is not sensitive enough, leading to low or falsely negative results, or where detection earlier in a disease progression would benefit the...Full Text Available

International Nuclear Information System (INIS)

In the fields of medical imaging, geophysical well logging, and industrial radiography, it is often of interest to characterize the spatially distributed sensitivities of neutron and gamma-ray measurement devices to the physical properties of the materials being examined. For instance, one may wish to know how the count rate in a detector varies in response to small changes in the local density of the irradiated object as a function of position. Experimental determination of such sensitivity functions is often impractical. Consequently, we have developed a general three-dimensional Monte Carlo numerical technique that allows us to directly compute the differential sensitivity of an arbitrary integral response parameter, such as a time- or energy-discriminated count rate, with respect to the spatial distribution of macroscopic cross sections and sources in the irradiated medium. Sensitivities to object ...

International Nuclear Information System (INIS)

The properties of individual radioactive particles present in a sample, such as a swipe, are more interesting than bulk properties of the sample. The present work focuses on instrumentation that provides position-sensitive spectral information non-destructively from the sample. The experimental part of the work was realized using a device called PANDA (Particles And Non-Destructive Analysis). The detector setup used in the study contains a broad-energy HPGe gamma-ray detector and a position-sensitive alpha detector. Both detectors are connected to a time-stamping event-mode data acquisition system. The method is shown to locate particles with sub-millimetre accuracy and distinguish the interesting particles from non-interesting ones. (author)

Science.gov (United States)

In this paper, four different types of pulsed eddy current (PEC) probe are designed and their performance of detecting wall thickness reduction is compared. By using the backward difference method in time and the finite element method in space, PEC signals from various thickness and materials are numerically calculated and three features of the signal are selected. Since PEC signals and features are obtained by various types and sizes of probe, the comparison is made through the normalized features which reflect the sensitivity of the feature to thickness reduction. The normalized features indicate that the shielded reflection probe provides the best sensitivity to wall thickness reduction for all three signal features. Results show that the best sensitivity to thickness reduction is achieved by the peak value, but also suggest that the time to peak can be a good candidate because of its linear relationship with the ...

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The response regulator protein is a core element of two-component signaling pathway. In this study, we investigated functions of BRRG-1 of Botrytis cinerea, a gene that encodes a putative response regulator protein, which is homologous to Rrg-1 in Neurospora crassa. The BRRG-1 gene deletion mutant ?Brrg1-62 was unable to produce conidia. The mutant showed increased sensitivity to osmotic stress mediated by NaCl and KCl, and to oxidative stress generated by H2O2. Additionally, the mutant was more sensitive to the fungicides iprodione, fludioxonil, and triadimefon than the parental strain. Western-blot analysis showed that the Bos-2 protein, the putative downstream component of Brrg-1, was not phosphorylated in the ?Brrg1-62. Real-time polymerase chain reaction assays showed that expression ...

International Nuclear Information System (INIS)

Somatostatin receptor scintigraphy (SRS) is a valuable method for the detection of somatostatin receptor-positive lesions. Most gastrinomas (over-)express the somatostatin receptor subtype 2 which can be targeted by In-111 labeled Octreotide. Different studies show a high sensitivity of SRS for the localization and staging of gastrinomas. SRS seems to be superior to other non-invasive imaging modalities and has been proven to significantly contribute to patient management. However, the sensitivity depends on the size and exact localization of the tumors. Smaller lesions and lesions located in the duodenum show a significantly lower sensitivity. In any case, SRS belongs to the routine imaging procedure for gastrinomas for localization and staging and can also be used for evaluation of the tumor progression. (author)

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A sensitive hydrogen peroxide (H2O2) sensor was fabricated based on graphene-Pt (GN-Pt) nanocomposite. The GN-Pt was synthesized by photochemical reduction of K2PtCl4 on GNs, and characterized by atomic force microscope (AFM), transmission electron microscope (TEM), and energy-dispersive X-ray spectroscopy (EDS). Electrochemical investigations indicated that the GN-Pt exhibited a high peak current and low overpotential towards the reduction of H2O2. The GN-Pt modified glass carbon electrode displayed a wide linear range (2-710mM), low limit of detection (0.5mM) and good selectivity for detection of H2O2 with a much higher sensitivity than that of Pt nanoparticles or graphene modified electrode.

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The authors have developed a high-sensitivity real-time neutron radiography (NR) system by the use of the low power reactor of Kinki University. The system was constructed with a high efficiency neutron-photon converter, an image intensifier and a SIT TELEVISION camera. Some digital image processing techniques were applied for improving the quality of the real-time neutron images. By the use of this system, dynamic neutron imaging was performed successfully under the condition of a weak neutron field that was about two orders of magnitude lower than that of the standard NR system. The neutron flux, calculated from the fluctuation of the neutron response of the images, was nearly equal to the value measured by the foil activation method. From this fact, the efficiency for the neutron detection of the imaging system was estimated to be almost 100%. For the purpose of developing a system with higher sensitivity, consideration of neutron statistics ...

International Nuclear Information System (INIS)

In order to develop a numerical tool for the fast evaluation of CANDU refuelling schemes, a Linear Sensitivity Matrix method (LSM) is developed. It assumes that all the effects caused by various perturbations to the core state are independent to each other and the core response to a perturbation is proportional to its magnitude. In this way, the main core parameters of a refuelling scheme can be derived by simple algebraic operations with the use of pre-calculated sensitivity matrices, without resorting to the complicated and time-consuming 3D core calculation. Verification against the Qinshan CANDU reactor operation history demonstrates that LSM is capable of generating accurate results and running very fast for evaluating a refuelling scheme. (authors)

UK PubMed Central (United Kingdom)

Oligonucleotide DNA probes complementary to the hypervariable region of the 16S rRNA of Bacteroides forsythus were tested for their specificity and sensitivity against reference and clinical isolates...Full Text Available

UK PubMed Central (United Kingdom)

Temperature sensing is crucial for homeotherms, including human beings, to maintain a stable body core temperature and respond to the ambient environment. A group of exquisitely temperature-sensitive...Full Text Available

UK PubMed Central (United Kingdom)

Peri-prosthetic infections are notoriously difficult to treat as the biomaterial implant is ideal for bacterial adhesion and biofilm formation, resulting in decreased antibiotic sensitivity....Full Text Available

UK PubMed Central (United Kingdom)

OBJECTIVE--To review and analyse the changing incidence of gonorrhoea and the increasing antibiotic resistance in gonococci in Australia from 1981 to 1991. DESIGN--Use of data from the sample of gonorrhoea...Full Text Available

UK PubMed Central (United Kingdom)

In vitro the binding of polyribosomes to smooth endoplasmic-reticulum membranes is more sensitive to ionic strength than is the binding to rough endoplasmic-reticulum membranes. Polyribosomes...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundSensitization to house dust mite allergens is strongly correlated with asthma. Der p 7 elicits strong IgE antibody and T-cell responses in mite allergic...Full Text Available

UK PubMed Central (United Kingdom)

Electrophysiological events are of central importance during the phagocyte respiratory burst, because NADPH oxidase is electrogenic and voltage sensitive. We investigated the recent suggestion that...Full Text Available

UK PubMed Central (United Kingdom)

Gonadal, adrenal, and thyroid hormones affect the brain directly, and the sensitivity to hormones begins in embryonic life with the appearance of hormone receptor sites in discrete populations of neurons....Full Text Available

UK PubMed Central (United Kingdom)

Trichomonas vaginalis is an important pathogen in both men and women. Culture is considered the diagnostic gold standard, although studies have shown that PCR is more sensitive than...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

In this paper, the compulsory site requirements and the site design assumptions which are being used for the present ITER plant are briefly described. A set of different parameters from the site design assumptions is also described, which was adopted as an additional exercise for cost sensitivity analysis of the ITER plant for these parameters. (orig.) 1 refs.

Science.gov (United States)

fotosintesis de especies previamente investigadas en la Antartida continental y capacidad de produccion de semillas y tasa de germinacion de las dos pla ...

UK PubMed Central (United Kingdom)

The results of antibiotic tests on bacterial pathogens freshly isolated from avian tissues and bovine milk are presented. Coliform isolates from the avian species showed an increased resistance to...Full Text Available

Science.gov (United States)

A roller bearing hot box sensor utilizing a metallic temperature sensitive elongated wire element. The wire element contacts at temperatures in the range of about 125 F to about 225 F so that when the contraction movement of the wire is attached to a conn...

UK PubMed Central (United Kingdom)

PurposeEctopic expression of light-sensitive proteins, such as channelrhodopsin-2, represent a novel approach for restoring light-detection capabilities to degenerated retina. A...Full Text Available

UK PubMed Central (United Kingdom)

The increasing demand for molecular diagnostics in clinical microbiology laboratories necessitates automated sample processing. In the present study, we evaluated the performance of the MagNA Pure LC...Full Text Available

UK PubMed Central (United Kingdom)

The relative sensitivities of different protocols for detecting cytomegalovirus nucleic acid sequences in histological specimens, using a biotinylated cDNA probe, were assessed. Several commonly used...Full Text Available

UK PubMed Central (United Kingdom)

A rapid, sensitive, and simple method was developed to detect the sapstain fungi Ophiostoma piceae and O. quercus in stained wood. By using microwave heating for DNA...Full Text Available

UK PubMed Central (United Kingdom)

Target of rapamycin (TOR) kinases control cell growth through two functionally distinct multiprotein complexes. TOR complex 1 (TORC1) controls temporal cell growth and is sensitive to rapamycin, whereas...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The use of radiochemical detectors in the A approx. = 90 mass region to measure 14 MeV neutron fluences is investigated from the standpoint of cross section sensitivities. Specifically, /sup 90/Zr and /sup 89/Y neutron-induced cascades leading to the production of /sup 89/Zr, /sup 88/Zr, /sup 88/Y, and /sup 87/Y are studied in a one-energy-group approximation, and the sensitivities of the measured ratios R/sub Z/ = /sup 88/Zr//sup 89/Zr and R/sub Y/ = /sup 87/Y//sup 88/Y to the input cross sections are delineated. The most sensitive cross section in each cascade is the cross section that dominates the production of the final isotope in the chain. Only one of the isomeric levels in /sup 90/Zr contributes importantly to the Zr cascade. Burnback (n,..gamma..) and burnup (n,p) reactions are also considered. The (n,..gamma..) effects are small, but (n,p) effects can be substantial due to low energy enhancements of (n,p) cross ...

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The development and evaluation of a post-column reaction detector sensitive to platinum(II) complexes is presented in which sodium bisulfite is used as the derivatizing agent with potassium dichromate as an activating agent. The influences of mobile phase changes (i.e., pH, organic modifiers, electrolytes), oxygen, metal ions, and order of reagent addition on reaction kinetics and product yield are defined and used in optimization of detector response. Detection at lambda/sub max/ 290 nm results in an on-line post-column sensitivity of 40-60 ng/mL for selected cis-dichloroplatinum complexes and a sensitivity of 300-1200 ng/mL for four (substituted)-malonato-platinum complexes. The reaction detector is used to monitor the kinetics of aquation of cisplatin (CDDP) and to quantitate CDDP degradation in plasma. As the sensitivity for CDDP in plasma is comparable to that achieved from high pressure liquid ...

UK PubMed Central (United Kingdom)

AbstractGenetic-variant analysis of rabies viruses provides the most sensitive epidemiologic tool for following the spread and persistence of these viruses in their wildlife hosts. Since...Full Text Available

UK PubMed Central (United Kingdom)

Voxel-based prescriptions of deliberately non-uniform dose distributions based on molecular imaging, so-called dose painting or theragnostic radiation therapy, require specification of a transformation...Full Text Available

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This article consists of a series of manufacturer's descriptions outlining specifications of underground monitoring equipment which range in complexity from gas sensitive personal badges to full mine monitoring systems. 8 figs.

UK PubMed Central (United Kingdom)

An influential neural model of face perception suggests that the posterior superior temporal sulcus (STS) is sensitive to those aspects of faces that produce transient visual changes, including facial...Full Text Available

UK PubMed Central (United Kingdom)

Major breakthroughs have recently been reported that can help overcome two inherent drawbacks of NMR: the lack of sensitivity and the limited memory of longitudinal magnetization. Dynamic nuclear polarization...Full Text Available

UK PubMed Central (United Kingdom)

The somatic sensory system responds to stimuli of distinct modalities, including touch, pain, itch, and temperature sensitivity. In the past century, great progress has been made in understanding the...Full Text Available

International Nuclear Information System (INIS)

Most superconductors are quite sensitive to irradiation defects. Critical temperatures may be depressed, critical currents may be increased, by irradiation, but other behaviours may be encountered. In compounds, the sublattice in which defects are created is of significant importance. 24 refs.

UK PubMed Central (United Kingdom)

A fluid-phase immunoradiometric assay has been developed which identifies an antigen on the Factor VIII (antihemophilic factor) procoagulant protein. This sensitive and quantitative assay is not influenced...Full Text Available

UK PubMed Central (United Kingdom)

To examine the association of human papillomavirus (HPV) infection with anal squamous cell carcinoma, the authors applied the highly sensitive polymerase chain reaction (PCR) and in situ hybridization...Full Text Available

UK PubMed Central (United Kingdom)

The sensitive explosives used in initiating devices like primers and detonators are called primary explosives. Successful detonations of secondary explosives are accomplished by suitable sources of...Full Text Available

UK PubMed Central (United Kingdom)

Neurons in the hippocampal CA1 region are particularly sensitive to oxidative stress (OS), whereas those in CA3 are resistant. To uncover mechanisms for selective CA1 vulnerability to OS, we...Full Text Available

UK PubMed Central (United Kingdom)

Female mammals are particularly sensitive to changes in food availability. The mechanisms that affect sexual behavior and food intake are closely related to one another; chief among the mechanisms...Full Text Available

UK PubMed Central (United Kingdom)

Rotazyme II, which is a shorter version of Rotazyme (less than 3 h), was compared with electron microscopy and Rotazyme for sensitivity and specificity on 229 human stool specimens. Compared with electron...Full Text Available

UK PubMed Central (United Kingdom)

SummaryEpigenetic drugs have been shown to enhance gene expression and drug sensitivity in ovarian cancer cell lines and animal models. Based on promising pre-clinical studies,...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThiazolidinediones (TZDs) activate peroxisome proliferator-activated receptor gamma (PPARγ) and are used clinically to help restore peripheral insulin sensitivity...Full Text Available

UK PubMed Central (United Kingdom)

Hemoglobin and zinc protoporphyrin (ZPP) tests are commonly used to screen for iron deficiency, but little research has been done to systematically evaluate the sensitivity and specificity of these...Full Text Available

UK PubMed Central (United Kingdom)

In both humans and songbirds, infants learn vocalizations by imitating the sounds of adult tutors with whom they interact during an early sensitive period. Vocal learning occurs in few animal taxa;...Full Text Available

UK PubMed Central (United Kingdom)

Attention has shifted from the treatment of colorectal cancer (CRC) to chemoprevention using aspirin and folic acid as agents capable of preventing the onset of colon cancer. However, no sensitive...Full Text Available

International Nuclear Information System (INIS)

The applicability of two nuclear analytical methods: radionuclide X-ray fluorescence analysis and radiometric titrations based on precipitate formations was studied in order to determine the heptacaine hydrochloride in solutions. The applied methods were evaluated based on the obtained sensitivity values. (author).

UK PubMed Central (United Kingdom)

AIMS: To evaluate the sensitivity of the Roche Cobas, Roche Amplicor plate kit, ligase chain reaction (LCR), and an in house polymerase chain reaction (PCR) by titration of purified elementary bodies...Full Text Available

UK PubMed Central (United Kingdom)

Cystic neoplasms of the pancreas are increasingly recognized due to the expanding use and improved sensitivity of cross-sectional abdominal imaging. Major advances in the last decade have led to an...Full Text Available

UK PubMed Central (United Kingdom)

Vulnerable periods during the development of the nervous system are sensitive to environmental insults because they are dependent on the temporal and regional emergence of critical developmental processes...Full Text Available

International Nuclear Information System (INIS)

A photon-induced x-ray fluorescence method allowing the simultaneous determination of iron, copper, zinc, bromine and rubidium in human blood and blood plasma samples is described. The method is reliable and has a good sensitivity for a wide range of elements. (author).

UK PubMed Central (United Kingdom)

A commercial multiplex real-time PCR assay (Cepheid Xpert C. difficile assay) for the diagnosis of Clostridium difficile infection was evaluated. The sensitivity and...Full Text Available

UK PubMed Central (United Kingdom)

Colour television is examined as an attempt to imitate the human visual system in image formation, spectral sensitivities, adaptation, contrast effects, signal processing, signal modulation, signal...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundEvent-related potentials (ERPs) may be used as a highly sensitive way of detecting subtle degrees of cognitive dysfunction. On the other hand, impairment of cognitive skills...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

To sensitize the public opinion and change the energy consumption habits, the ADEME (french Agency for the environment and the energy mastership) published a document on the climatic change problem and its consequences. A state of the art of the situation, the international agreements and solutions are provided. (A.L.B.)

UK PubMed Central (United Kingdom)

The mitogen-activated protein kinase/extracellular regulated kinase (MAPK/ERK) pathway plays a key role in mediating estrogen actions in the brain and neuronal sensitization during inflammation....Full Text Available

Science.gov (United States)

Results of feasibility experiments for determining the mineral content of individual stains on special Sensitized Paper are presented. The stains were formed on the paper by the impaction of laboratory generated salt water droplets. Of the techniques exam...

UK PubMed Central (United Kingdom)

1. The effect of capsaicin pre-treatment on adrenal catecholamine (CA) secretion in response to stress is controversial. In earlier experiments performed under pentobarbitone anaesthesia, the release...Full Text Available

CERN Document Server

Top quark is extremely sensitive to non-standard CP violating phases. General strategies for exposing different types of phases at the NLC are outlined. SUSY phase(s) cause PRA in $t\\to Wb$. The transverse polarization of the $\\tau$ in the reaction $t\\to b\\tau\

UK PubMed Central (United Kingdom)

A sensitive and specific detection method was developed for Xanthomonas hyacinthi; this method was based on amplification of a subsequence of the type IV fimbrial-subunit gene fimA...Full Text Available

UK PubMed Central (United Kingdom)

There is no gold standard diagnostic test for the detection of bovine cryptosporidiosis. Infection is usually highest in 2-week-old calves, and these calves also excrete high numbers of oocysts. These...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

This paper introduces briefly neutrinoless Double Beta Decay and discusses its implications for neutrino physics. After a presentation of general experimental concepts, such as the various proposed methodological approaches and the sensitivity, the current experimental situation is concisely reviewed.

UK PubMed Central (United Kingdom)

Sperm competition theory predicts that males should invest prudently in ejaculates according to levels of female promiscuity. Males may therefore be sensitive to cues in their social environment associated...Full Text Available

UK PubMed Central (United Kingdom)

Low concentrations of sugars altered the sensitivity of seed germination to inhibition by exogenous abscisic acid (ABA). Germination of wild-type and ABA-insensitive (abi) Arabidopsis...Full Text Available

UK PubMed Central (United Kingdom)

1. An acid ninhydrin reagent was found to react specifically in forming a pink product (E_max. 560mμ) with cysteine. 2. The method was highly sensitive for the determination...Full Text Available

UK PubMed Central (United Kingdom)

Histone H2AX phosphorylation on a serine four residues from the carboxyl terminus (producing γH2AX) is a sensitive marker for DNA double-strand breaks (DSBs). DSBs may lead to cancer...Full Text Available

CERN Document Server

Spectroscopy of antihydrogen has the potential to yield high-precision tests of the CPT theorem and shed light on the matter-antimatter imbalance in the Universe. The ALPHA antihydrogen trap at CERN's Antiproton Decelerator aims to prepare a sample of antihydrogen atoms confined in an octupole-based Ioffe trap and to measure the frequency of several atomic transitions. We describe our techniques to directly measure the antiproton temperature and a new technique to cool them to below 10 K. We also show how our unique position-sensitive annihilation detector provides us with a highly sensitive method of identifying antiproton annihilations and effectively rejecting the cosmic-ray background.

International Nuclear Information System (INIS)

The proposed Sudbury Neutrino Observatory is based on a Cherenkov detector which has a total of 1000 tonne of heavy water and 1800 tonne of light water for its sensitive volume. The detector is optimized for the measurement of extra-terrestrial low energy electron neutrinos and electron antineutrinos spectra as well as the total neutrino flux independent of neutrino flavours. It will delineate the Standard Solar Model and neutrino propagation aspects of the solar neutrino problem, provide detailed information on the dynamics of stellar collapse and measure neutrino masses and oscillation parameters with high sensitivity.

International Nuclear Information System (INIS)

This short communication aims to update the review of non-nitro radiation sensitizers (Shenoy and Singh 1985) and correct omissions. Work is mentioned and bibliography given for studied of cis-platinum, potassium permanganate, cobalt hexammine, sodium bromide, dimethylsulphoxide, zinc and copper ions, organic nitroxyl free radicals (TAN,TMPN and NPPN + PNAP), halogenated pyrimidines, organic and inorganic iodine containing compounds, diacetyl, acetone and acetophenone, rho-hydrobenzoic acid and its esters, pentobarbitone and secobarbitone, heparin and 9-anilinoacridines, dehydropiandosterone and paraquat. (U.K.).

Energy Technology Data Exchange (ETDEWEB)

The Systems Design Study (SDS) identified technologies available for the remediation of low-level and transuranic waste stored at the Radioactive Waste Management Complex`s Subsurface Disposal Area at the Idaho National Engineering Laboratory. The SDS study intentionally omitted the costs of transportation and disposal of the processed waste and the cost of decommissioning the processing facility. This report provides a follow-on analysis of the SDS to explore the basis for life-cycle cost segments of transportation, disposal, and facility decommissioning; to determine the sensitivity of the cost segments; and to quantify the life-cycle costs of the 10 ex situ concepts of the Systems Design Study.

Energy Technology Data Exchange (ETDEWEB)

The susceptibility to intergranular corrosion of different heats of Alloy 800 was evaluated by three different methods: the ASTM A 262 Practice E (or modified Strauss test), the Electrochemical Potentiokinetic Reactivation method, and by magnetic-susceptibility measurements. Reasonably good agreement was found between the sensitization areas as defined by the three methods in the TTS diagrams. In some cases the area defined by the Strauss test was slightly smaller than that determined by the other two tests. The differences might be explained by the fact that the methods present different sensitivities to the chromium concentration at the grain boundaries. 27 references, 11 figures, 3 tables.

Energy Technology Data Exchange (ETDEWEB)

Experiments in a homogeneous charge compression ignition (HCCI) engine have been conducted with four gasoline surrogate fuel blends. The pure components in the surrogate fuels consisted of n-heptane, isooctane, toluene, ethanol and diisobutylene and fuel sensitivities (RON-MON) in the fuel blends ranged from two to nine. The operating conditions for the engine were p{sub in}=0.1 and 0.2 MPa, T{sub in}=80 and 250 C, {phi}=0.25 in air and engine speed 1200 rpm. A semidetailed chemical kinetic model (142 species and 672 reactions) for gasoline surrogate fuels, validated against ignition data from experiments conducted in shock tubes for gasoline surrogate fuel blends at 1.0{<=} p{<=}5.0MPa, 700{<=} T{<=}1200 K and {phi}=1.0, was successfully used to qualitatively predict the HCCI experiments using a single zone modeling approach. The fuel blends that had higher fuel sensitivity were more resistant to autoignition for ...

International Nuclear Information System (INIS)

A dispersion interferometer based on CO2 laser for measurements of plasma line density in the gas dynamic trap (GDT) experiment has been developed with sensitivity el>min ? 1.1013 cm-2, temporal resolution ?50 ns. The main advantages of the interferometer are compactness and low sensitivity to vibrations. The interferometer does not require specific vibration isolation structure and can be mounted directly on the working chamber of the plasma device. The above mentioned advantages have been successfully demonstrated in the Gas Dynamic Trap experiments.

International Nuclear Information System (INIS)

We describe a position-sensitive event-counting microchannel plate detector with a quadrant anode readout system that combines the advantages of several centroid-finding readout techniques. The relative amount of charge collected by each quadrant of the anode mounted behind the output side of the microchannel plate is used to localize each event. The position-sensitive area is about 80% of the active microchannel plate surface. By changing a single voltage a remote-controlled image magnification can be achieved. Due to a correction function that minimizes image distortions the imaging characteristics of this low-cost readout system are similar to those of expensive resistive anodes. (orig.).

Energy Technology Data Exchange (ETDEWEB)

Diffusion of radon in a bed of activated charcoal is described by diffusion equations. An analytical solution of these equations is presented for the case of constant radon concentration in the atmosphere. The solutions are given separately for short term and long term exposure. An analytical form of the calibration constant f for long term exposure and constant radon concentration in air, was found. A numerical method and computer code based on the method of finite elements is developed for the case of variable radon concentration in air. This program simulates radon adsorption by the activated charcoal bed, enabling determination of sensitivity. The dependence of sensitivity on different parameters, such as temperature, thickness of the charcoal, etc. was studied using this program. (orig.) 10 refs.

International Nuclear Information System (INIS)

The threshold values of indicator species and ratios delineating the transition between NO_x and VOC sensitivity of ozone formation are assumed to be universal by various investigators. However, our previous studies suggested that threshold values might vary according to the locations and conditions. In this study, threshold values derived from various model simulations at two different locations (the area of Switzerland by UAM Model and San Joaquin Valley of Central California by SAQM Model) are examined using a new approach for defining NO_x and VOC sensitive regimes. Possible definitions for the distinction of NO_x and VOC sensitive ozone production regimes are given. The dependence of the threshold values for indicators and indicator ratios such as NO_y, O_3/NO_z, HCHO/NO_y, and H_2O_2/HNO_3 on the definition of NO_x and VOC sensitivity is discussed. Then the variations of threshold values under low ...

Energy Technology Data Exchange (ETDEWEB)

The time-temperature-precipitation diagrams and the resulting time-temperature-sensitization diagrams have been established and are presented for today's current nickel-chromium-molybdenum alloys C-4, C-276, 22 and the recently developed alloy 59. Compared to those materials alloy 625 behaves differently due to its high niobium content. In addition, also the precipitation and sensitization of alloy G-3 has been established. Under the materials considered alloy C-276 has the strongest tendency to precipitate the intermetallics Mu and P together with the carbide M{sub 6}C at intermediate temperatures, followed by the alloys 22 and 59. The tendency to sensitization in the sense of the 50{mu}m (2 mils) intercrystalline penetration criterion when exposed to the ASTM G-28, method A test solution is greatest with alloy C-276, and decreases over the alloys 22, 59 and G-3 to alloy 625. Sensitization is ...

Energy Technology Data Exchange (ETDEWEB)

The themal neutron sensitivities of SEI and Toshiba FD-P10-7 radiophotoluminescent silver activated metaphosphate glass dosimeters have been measured and studied theoretically. The graphite thermal neutron column attached to the AEEW reactor NESTOR was utilised as a source of thermal neutrons with minimal fast neutron and gamma-ray contamination. Both the neutron removal and gamma correction measurement techniques were applied and these gave consistent results. It was found that the thermal neutron sensitivity of the Toshiba dosimeters is comparable to the most neutron intensitive thermoluminescent materials available. Because of their larger size and higher silver concentration, however, SEI dosimeters are an order of magnitude more neutron sensitive. The neutron sensitivity of FD-7 glass has not been reported previously, whereas in the case of SEI glass, there exists a modest body of previous work on ...

International Nuclear Information System (INIS)

The aim of the study was the attempt to evaluate the influence of two different methods of cardiac perfusion SPECT reconstruction (FBP and ITW) on clinical efficacy in diagnosing the coronary artery disease as well as the cardiac ischemia detection in three areas of heart vascularized by main coronary arteries: LAD, LCX and RCA with the use of artificial neural networks (ANN). The study was performed retrospectively with the use of the diagnostic image records as well as clinical dataset of 43 patients. Myocardial perfusion stress/rest SPECT study and X-ray coronarography data were evaluated for each patient. The results of coronary angiography were considered the reference method. The cardiac SPECT data were reconstructed using the two different methods: filtered backprojection (FBP) and iterative Wallis method (ITW). The local perfusion deficits denominated in stress and rest study in three main vessel cardiac segments were the main input values for the ANN. The ...

Science.gov (United States)

BackgroundXMRV (xenotropic murine leukemia virus-related virus) is the first known example of an exogenous gammaretrovirus that can infect humans. A limited number of reports suggest that XMRV is intrinsically resistant to many of the antiretroviral drugs used to treat HIV-1 infection, but is sensitive to a small subset of these inhibitors. In the present study, we used a novel marker transfer assay to directly compare the antiviral drug sensitivities of XMRV and HIV-1 under identical conditions in the same host cell type.ResultsWe extend the findings of previous studies by showing that, in addition to AZT and tenofovir, XMRV and HIV-1 are equally sensitive to AZddA (3'-azido-2',3'-dideoxyadenosine), AZddG (3'-azido-2',3'-dideoxyguanosine) and adefovir. These results indicate that specific 3'-azido or acyclic nucleoside analog inhibitors of HIV-1 reverse transcriptase (RT) also block XMRV infection with comparable efficacy ...

International Nuclear Information System (INIS)

The purpose of this research was to: a) evaluate variations in sensitivity and uniformity of SPECT detectors during 360"0 rotation, b) explore the causes of the variations and c) to discuss a correction procedure. A flood source consisting of a lucite disc 47.7 cm in diameter containing 3 microcuries of Co-57 was constructed. This source can be firmly attached to the uncollimated detector guaranteeing no detector-source geometry change during rotation. Four different SPECT cameras were tested. Measurements were obtained at 45"0 intervals throughout a 360"0 rotation, and repeated in 3 different orientations with respect to the earth's magnetic field. In one camera the effects of the direction and strength of induced magnetic fields were studied. All detectors showed cyclic rotational variations in sensitivity; in three cameras 6%, in one 3%. The amplitude and phase of the sensitivity variation curves and the variations in ...

International Nuclear Information System (INIS)

Aim of this study was to evaluate the sensitivity of virtual colonoscopy (CT colonography) in the identification of colorectal cancer and to define the limitations and the advantages of this imaging modality, as well as indications to the examination. It was examined prospectively 62 symptomatic patients aged 36 to 82 years (28 women and 34 men). All patients underwent both conventional and virtual colonoscopy on the same day; the conventional examination allowed exploration of the entire colon. Conventional colonoscopy identified 89 lesions 3-50 mm in diameter, namely 84 benign and 5 malignant lesions. No lesions were identified in 12 patients. CT colonography identified 52 of the 89 lesions, with 57.1% diagnostic accuracy. They were 11 false positives (82.5% positive predictive value and 52.2% specificity) and 37 false negatives (24.5% negative predictive value and 58.4% sensitivity). Sensitivity was significantly higher ...

Energy Technology Data Exchange (ETDEWEB)

The radiosensitivity of spermatogonial stem cells of C3H/HeHx101/H F[sub 1] hybrid mice was determined by counting undifferentiated spermatogonia at 10 days after X-irradiation. During the spermatogenic cycle, differences in radiosensitivity were found, which were correlated with the proliferative activity of the spermatogonial stem cells. In stage VIII[sub irr], during quiescence, the spermatogonial stem cells were most radiosensitive with a D[sub 0] of 1.4 Gy. In stages XI[sub irr]-V[sub irr], when the cells were proliferatively active, the D[sub 0] was about 2.6 Gy. Based on the D[sub 0] values for sensitive and resistant spermatogonia and on the D[sub 0] for the total population, a ratio of 45:55% of sensitive to resistant spermatogonial stem cells was estimated for cell killing. When the present data were compared with data on translocation induction obtained in mice of the same genotype, a close fit was obtained when the translocation ...

International Nuclear Information System (INIS)

Full text. Here we present a status report of the Schenberg antenna, which started commissioning runs in September 2006 under the full support of FAPESP. In its first commissioning runs we tested three preliminary parametric transducer systems, which did not achieve a high enough performance for placing the antenna sensitivity in the range of the calibrator capacitor. Instead of improving the calibrator, making it capable of introducing a larger input force, we decided to go to a radical upgrading operation: replacing the three transducers for a complete set of six transducers, with better sensitivity and arranged according to the truncated icosahedron configuration, plus two extra ones; starting to install the dilution refrigerator; installing wires, cables, and amplifiers for the complete set of transducer circuits; and a new suspension and vibration isolation system for the cabling and microstrip antennas. We also have been developing a new ...

Energy Technology Data Exchange (ETDEWEB)

Optimal capacitor placement determines the size, type, and location of capacitors to be installed on a radial distribution feeder that will reduce peak power and energy losses while minimizing the costs of investment and installation of the capacitor banks. This paper describes a sensitivity-based optimal placement of capacitors that employs a new load characterization scheme using a voltage-current-angle-logger. The proposed method allows modeling of loads of different power factors for different portions of the distribution feeder. The optimal solution is obtained by testing various combinations of capacitor banks (based on the smallest bank size specified by the user) and candidate nodes along the distribution feeder, and calculating the resultant savings. In order to reduce solution time, the candidate nodes are ranked according to their sensitivity factors. The highest ranking nodes are considered first in the optimization process. At a ...

Energy Technology Data Exchange (ETDEWEB)

In this study, sensitivity analysis of 100 MWth chemical looping combustion combined cycle (CLC-CC) plant based on fuel cost were performed. By performance analysis, net efficiency of natural gas/syngas fueled CLC-CC plant was 53-54%, corresponding to previous research. We used Chemical Engineering Plant Cost Index and Guthrie method to evaluate plant cost. For syngas fueled CLC-CC plant, the plant cost was higher since lower heating value (LHV) of syngas was lower than that of natural gas and cost of electricity (COE) was also higher since the cost of syngas was higher than that of natural gas. By sensitivity analysis, it was shown that the cost of syngas should be less than 5.3 $/GJ in order to make COE lower than 5.8 c/kWh which was COE of natural gas CLC-CC plant. 15 refs., 2 figs., 5 tabs.

Energy Technology Data Exchange (ETDEWEB)

One of the major achievements of the magnet R&D program for the Superconducting Super Collider (SSC) is the fabrication and test of a series of 20 5-cm aperture, 15-m long dipole magnet prototypes. The ramp rate sensitivity of these magnets appears to fall in at least two categories that can be correlated to the manufacturer and production batch of the strands used for the inner-coil cables. The first category, referred to as type-A, is characterized by a strong quench current degradation at high ramp rates, usually accompanied by large distortions of the multipole fields and large energy losses. The second category, referred to as type-B, is characterized by a sudden drop of quench current at low ramp rates, followed by a much milder degradation at larger rates. The multipole fields of the type-B magnets show little ramp-rate sensitivity, and the energy losses are smaller than for the type-A magnets. The behavior of the Type-A magnets can ...

Energy Technology Data Exchange (ETDEWEB)

The present investigation deals with the fabrication of liquid petroleum gas (LPG) sensor based on semiconducting oxide SnO{sub 2}. The gas sensor elements have been prepared by conventional solid state route. Addition of noble metal sensitizer, palladium and grain growth inhibitor, aluminum silicate to the base material SnO{sub 2}, not only improved the sensitivity towards LPG but also the selectivity in the presence of CO and CH{sub 4} gases. Out of various sensor compositions, SnO{sub 2}:Al{sub 2}Si{sub 2}O{sub 7} (35 wt.%):Pd (1.5 wt.%) sintered at 800 C for 5 h has shown high sensitivity (0.97) towards LPG at an operating temperature of 350 C. Different characterization techniques have been employed, such as differential thermal analysis (DTA), surface area analyzer, X-ray diffraction (XRD), to study the formation of SnO{sub 2}, surface area and crystallite size, respectively. The results suggested the possibility of ...

Energy Technology Data Exchange (ETDEWEB)

A heavy ion gas detector system consisting of a Bragg-curve spectroscopy ionization chamber for particle identification and a multiwire proportional chamber as position sensitive fast trigger device is described. The Bragg IC has been tested with several beams up to Z=36 to investigate some aspects of the BCS method. Results are reported on energy resolution and linearity, Z resolving power and mass sensitivity. The energy resolution is well below 1%. The Bragg-peak amplitude is fairly independent of the energy in a wide energy range and single elements are identified up to Z=38 with a resolving power Z/..delta..Zproportional50-80. Isotope identification by range measurement is limited by the straggling in the ionization process and the mass resolving power is M/..delta..Mproportional20-26 for S and Si isotopes. The MWPC allows subnanosecond time resolution and position identification along the in-plane coordinate within +-0.5 mm.

Energy Technology Data Exchange (ETDEWEB)

This report compares the performance characteristics of /sup 10/B-lined and fission-neutron detectors in gamma-ray fluxes typical of the fields to be encountered during nondestructive testing of irradiated light-water fuel assemblies stored in water. Using the optimum time constants for each of the /sup 10/B-lined detectors, the 0.25-in.-dia detector had a 5% loss in neutron count sensitivity at 7000 rad/h. Similarly, the 0.5-in.-dia detector had a 7% loss at 13,000 rad/h and the 1-in.-dia detector had a 5% loss in sensitivity at 1000 rad/h. Uranium-235 fission chambers were operated successfully in fields above 100,000 rad/h with no loss in neutron counting sensitivity. Shielding calculations were done to determine the appropriate shield thickness needed for a /sup 10/B-lined neutron detector to operate in a 50,000 rad/h field, typical of light-water-reactor spent-fuel assemblies stored in water. 7 refs., 4 figs., 9 tabs.

Energy Technology Data Exchange (ETDEWEB)

The effect of chronic administration of phenobarbital on the binding of phorbol-12,13-dibutyrate (({sup 3}H)PDBu), an activator of protein kinase C (PKC), was examined in rat liver microsomes. A significant increase in the number of binding sites was observed in microsomes of Fisher 344 rats. However, no change appeared in liver cytosol binding of PDBu. Consequently, a translocation process of PKC is unlikely. The increase in ({sup 3}H)PDBu binding in liver microsomes is significant 24 h. after one injection of phenobarbital and reaches its maximum in 2 days. In other strains of rats (ACI and lean Zucker), significant differences were found in the increase of ({sup 3}H)PDBu binding in microsomes. Fisher 344 were the most sensitive, lean Zucker rats, the least sensitive. Those results parallel the pentoxy-resorufin O demethylase activity in the microsomes of the same animals. EC{sub 50} values for inhibition of ({sup 3}H)PDBu binding by ...

International Nuclear Information System (INIS)

Reference is made to Cheng and Leblond (Amer. J. Anat.; 141:537 (1974)) who used tritiated thymidine to kill cells synthesising DNA in the crypts of the small intestine. Amongst their findings was that very low doses caused measurable cell killing and that the killing was not random throughout the crypt but occurred selectively at the crypt base where stem cells are presumably located. It is here reported that the presence of hypersensitive cells at the base of the crypts can be demonstrated after whole-body X- or gamma-irradiation, and the time sequence for the production and loss of the killed cells is described together with their dose-response relationship. The studies were conducted on mice. The data were expressed as surviving rather than killed cells, and it was established that the crypt are amongst the most sensitive of mammalian cells. The mechanism by which these sensitive cells are killed is not known, but DNA damage can be ...

International Nuclear Information System (INIS)

Glutathione (GSH) depletion sensitizes human lung carcinoma (A549-T27) cells to the cytotoxic effects of Cd++. The effects of GSH depletion on Cd++ accumulation and Cd++-induced metallothionein (MT) content were investigated to determine the possible role of these Cd++ responses in the sensitization process. Cellular GSH was depleted to 20% to 25% of control levels with buthionine sulfoximine (BSO), or diethyl maleate (DEM), respectively. Neither treatment significantly affected Cd++-induced accumulation of exogenous 35s-cysteine into intracellular MT in a dose-dependent fashion. The results indicate that neither enhanced Cd++ accumulation nor reduced MT synthesis plays a primary role in affecting enhanced Cd++ cytotoxicity in A549 cells with reduced GSH levels. Although BSO inhibition of GSH synthesis enhanced MT synthesis, it sensitized the cells to Cd++, which suggests an additive effect of GSH and MT in cadmium ...

International Nuclear Information System (INIS)

Distinguishing between effects of natural and anthropogenic environmental factors on ecosystems is a fundamental problem in environmental science. In river systems the longitudinal gradient of environmental factors is one of the most relevant sources of dissimilarity between communities that could be confounded with anthropogenic disturbances. To test the hypothesis that in macroinvertebrate communities the distribution of species' sensitivity to organic toxicants is independent of natural longitudinal factors, but depends on contamination with organic toxicants, we analysed the relationship between community sensitivity SPEARorganic (average community sensitivity to organic toxicants) and natural and anthropogenic environmental factors in a large-scale river system, from alpine streams to a lowland river. The results show that SPEARorganic is largely independent of natural longitudinal factors, but strongly dependent on ...

Energy Technology Data Exchange (ETDEWEB)

In recent years, there has been increased interest in using early life stages of freshwater bivalves to test the toxicity of dissolved constituents in water. The authors have developed laboratory and in situ assays with artificially cultured Utterbackia imbecillis to examine effects of contaminants and existing conditions in embayments and rivers on mortality and reproductive success of unionid mussels. Age sensitivity of U. imbecillis to Cd and Cu was examined using both static acute and 8-day static renewal bioassays. Both aqueous and sediment exposures demonstrated greater sensitivity to Cd than Cu. LC{sub 50}`s for two-day old (2d) and 9d mussels were approximately half the LC{sub 50} calculated for 16d mussels in 48-hr bioassays with Cd. Additionally, acute assays were repeated twice to examine variability in response between different mussel cultures to the two metals. The results of this work reinforce the potential of juvenile U. ...

Energy Technology Data Exchange (ETDEWEB)

The possibility of improving the cold formability of wrought magnesium alloys is considered in light of their good hot forming characteristics. Magnesium alloy AZ31B sheet is selected as a model system. Parameters affecting formability, such as strain hardening rate, strain rate sensitivity, and the degree of anisotropy are examined systematically by conducting tensile tests over a range of temperatures (room temperature to 250 C) and strain rates (1 x 10{sup -5} to 0.1 s{sup -1}). The plastic anisotropy and deformation texture evolution are examined in samples aligned with the sheet rolling and transverse directions. Polycrystal plasticity simulations using a viscoplastic self-consistent (VPSC) formulation are used to model the observed anisotropy and texture evolution. The adjustable parameters in the model are the relative critical resolved shear stresses of the dislocation mechanisms known to operate within magnesium. The experimental results suggest that an ...

International Nuclear Information System (INIS)

The objective of this study was to determine the usefulness of parathyroid scintigraphy in histological estimation for secondary hyperparathyroidism (2HPT) using Tc-99m sestamibi or Tc-99m tetrofosmin. Tc-99m sestamibi (MIBI) and Tc-99m tetrofosmin (Tetro) parathyroid imaging following double-phase study, magnetic resonance imaging (MRI), and ultrasound were performed on 14 patients with 2HPT. All patients underwent parathyroidectomy. The uptake of two tracers in parathyroid areas was compared with the histopathologic findings. Forty-nine parathyroid glands were surgically explored and histologically proven to be hyperplastic. Of these, 42 were diagnosed with nodular type (N-type) hyperplasia, and 7 with diffuse type (D-type) hyperplasia. MIBI and Tetro parathyroid imagings detected 34 and 35 parathyroid glands, respectively. The sensitivity of MIBI was determined to be 76.2% (32/42) for N-type, and 28.6% (2/7) for D-type. The sensitivity of ...

Energy Technology Data Exchange (ETDEWEB)

Thin film ultraviolet detectors based on hydrogenated amorphous silicon alloys are realized with different diode structures (PIN, NIP, PN, and NP). The PIN and NIP detectors exhibit higher sensitivity in the ultraviolet spectrum and a significant lower dark current in comparison to the PN or NP structures. The best detector performance was achieved with a 33 nm thick PIN diode. This detector shows a maximum of quantum efficiency of 36.3% at a wavelength of 310 nm. By varying the thickness of the semi-transparent Ag front contact the selectivity of the detectors with the quantum efficiency peak at 320 nm can be adjusted. Thus, the spectral sensitivity of the detector shifts from a broad UV to a selective UV-B spectrum. (orig.)

Science.gov (United States)

Four-enzyme section of the shikimate pathway (Aro B, D, E, and K) of Streptococcus pneumoniae has been studied. Kinetic properties of the individual enzymes and three- and four-enzyme linked reactions have been characterized in vitro. On the basis of the data measured in spectrophotometric and LC-MS experiments, kinetic mechanisms of the enzymes have been suggested and all kinetic parameters have been identified. Kinetic models for these three- and four-enzyme sections of the shikimate pathway have been constructed and validated. The model of the four-enzyme section of shikimate pathway has been employed to design an inhibition-sensitive reconstituted pathway for a high-throughput screening effort on the shikimate pathway. It was demonstrated that using the model it was possible to optimize this reconstituted pathway in such a way to provide equal sensitivity of the enzymes to inhibition. PMID:16921527

CERN Document Server

The Baikal Neutrino Telescope has been operating in its NT200 configuration since April, 1998. The telescope has been upgraded in April, 2005, to the 10 Mton scale detector NT200+. It's main physics goal is the detection of signals from high energy neutrino cascades. NT200+ reaches a 3-year sensitivity of 2 \\times 10^{-7}cm^{-2}s^{-1}sr^{-1}GeV for an all-flavor diffuse cosmic E^{-2} neutrino flux for energies 10^2 TeV \\div 10^5 TeV. Desgin and sensitivity of NT200+ are described. NT200+ is forming the basic building block of a future km3-scale (Gigaton-Volume) Baikal Telescope. Research and development work on that next stage detector has started.

Energy Technology Data Exchange (ETDEWEB)

The feasibility of using of current-biased superconducting strips for radiation detection is investigated. Narrow Ta strips are exposed to 5.5 MeV [alpha]-particle radiation and the rise-time of the induced voltage pulses is measured as function of temperature and bias current. The rise-time of the voltage signal strongly depends on the site on the strip which is hit by the [alpha]-particle. In order to determine the spatial resolution of a superconducting strip detector, position-sensitive measurements were performed. The maximum lateral resolution estimated so far is 25[mu]m in a 7[mu]m wide, 340 nm thick and 0.6 mm long Ta-strip. (orig.)

International Nuclear Information System (INIS)

Stable boiloff of core water during a severe LWR accident, that is, boiloff driven only by the decay power generated below the water level, is tractable analytically and is relatively insensitive to axial power distribution. As might be expected, calculated accident event times are sensitive to the fidelity of the decay power model. During later stages of boiloff, heat transfer or transport of energy from above the water level to the residual water can result in an unstable condition during which the boiloff rate increases greatly. The unstable boiloff phenomenon illustrates the highly nonlinear influence of core heat transfer during meltdown and emphasizes the great accuracy requirements which attend the modeling of the accident during periods of enhanced heat transfer when significant zirconium oxidation is possible.

International Nuclear Information System (INIS)

A sensitivity analysis was conducted to evaluate the technical issues pertaining to possible destructive interactions between spent nuclear fuels (SNFs) and the stainless steel canisters. When issues are identified through such an analysis, they provide the technical basis for answering what if questions and, if needed, for conducting additional analyses, testing, or other efforts to resolve them in order to base the licensing on solid technical grounds. The analysis reported herein systematically assessed the chemical and physical properties and the potential interactions of the materials that comprise typical US Department of Energy (DOE) SNFs and the stainless steel canisters in which they will be stored, transported, and placed in a geologic repository for final disposition. The primary focus in each step of the analysis was to identify any possible phenomena that could potentially compromise the structural integrity of the canisters and to assess their ...

International Nuclear Information System (INIS)

We describe a position sensitive photon counting microchannel plate based detector with an improved quadrant anode (QA) readout system. The technique relies on a combination of the four planar elements pattern and an additional fifth electrode. The charge cloud induced by single particle detection is split between the electrodes. The measured charge values uniquely define the position of the initial event. QA has been first published in 1976 by Lampton and Malina. This anode configuration was undeservedly forgotten and its potential has been hardly underestimated. The presented approach extends the operating spatial range to the whole sensitive area of the microchannel plate surface and demonstrates good linearity over the field of view. Therefore, the novel image sensor results in spatial resolution better then 50?m and count rates up to one million events per second.

British Library Electronic Table of Contents (United Kingdom)

Novel fluoroalkyl end-capped vinyltrimethoxysilane oligomeric nanoparticles were prepared by the hydrolysis of the corresponding oligomer under alkaline conditions. The size of fluorinated nanoparticles thus obtained is of submicrometer levels and is not sensitive to the refractive indices of a variety of solvents; however, the turbidity of the dispersed fluorinated nanoparticles is extremely sensitive to the refractive indices of these solvents. In particular, the solvents of which the refractive indices are from 1.378 to 1.408 were found to afford the transparent colorless dispersed particle solutions. More interestingly, the modified glass surface treated with fluorinated nanoparticles exhibited a completely superhydrophobic characteristic (a water contact angle: 180?) with a nonwetting...

Energy Technology Data Exchange (ETDEWEB)

A time-of-flight (TOF) spectrometer has been constructed at the JAERI 20 MV tandem accelerator facility. A position-sensitive start detector, which consists of a thin carbon foil, microchannel plates and a resistive plate, was developed for the TOF measurements through the spectrometer. The time and position resolutions obtained were 120 ps and 0.3 mm for ..cap alpha.. particles from /sup 241/Am, respectively. A two-dimensional position-sensitive detector was also developed to measure the solid angle of the spectrometer and the maximum solid angle obtained was 9.5 msr. As a particle detector a Bragg curve ionization chamber was developed. From the Bragg curves of heavy ions in the detector, energies, ranges and Bragg curve peaks were measured and used for particle identification. The resolving power Z/..delta..Z of the atomic number was about 50.

Energy Technology Data Exchange (ETDEWEB)

In this work, we have investigated the capability of different bimetallic nanoparticle alloy combinations to be used in fibre optic sensors based on the technique of surface plasmon resonance. The metals considered for this analysis are silver, gold, copper and aluminium. The performance of the sensor with different bimetallic nanoparticle alloy combinations is evaluated and compared numerically. The performance is analysed in terms of three parameters: sensitivity, signal-to-noise ratio (SNR) and operating range for the sensing layer refractive index values. On the basis of the comparison and some logistic criteria, the best possible bimetallic alloy combinations along with a requisite alloy composition ratio are predicted. The bimetallic nanoparticle alloy combination is capable of simultaneously providing larger values of sensitivity, SNR and operating range, which is not possible with any single metallic nanoparticle layer.

Energy Technology Data Exchange (ETDEWEB)

An Oil Shale Mining Economic Model (OSMEM) was developed and executed for mining scenarios representative of commercially feasible mining operations. Mining systems were evaluated for candidate sites in the Piceance Creek Basin. Mining methods selected included: (1) room-and-pillar; (2) chamber-and-pillar, with spent shale backfilling; (3) sublevel stopping; and (4) sublevel stopping, with spent shale backfilling. Mines were designed to extract oil shale resources to support a 50,000 barrels-per-day surface processing facility. Costs developed for each mining scenario included all capital and operating expenses associated with the underground mining methods. Parametric and sensitivity analyses were performed to determine the sensitivity of mining cost to changes in capital cost, operating cost, return on investment, and cost escalation.

British Library Electronic Table of Contents (United Kingdom)

Summary Many important moral decisions, particularly at the policy level, require the evaluation of choices involving outcomes of variable magnitude and probability. Many economic decisions involve the same problem. It is not known whether and to what extent these structurally isomorphic decisions rely on common neural mechanisms. Subjects undergoing fMRI evaluated the moral acceptability of sacrificing a single life to save a larger group of variable size and probability of dying without action. Paralleling research on economic decision making, the ventromedial prefrontal cortex and ventral striatum were specifically sensitive to the "expected moral value" of actions, i.e., the expected number of lives lost/saved. Likewise, the right anterior insula was specifically sensitive to outcome p...

British Library Electronic Table of Contents (United Kingdom)

Manganese toxicity can cause a neurodegenerative disorder affecting cortical and basal ganglia structures with a neurological presentation resembling features of Parkinson's disease. Children are more sensitive to Mn-induced neurological dysfunction than adults, and recent studies from our laboratory revealed a marked sensitivity of male juvenile mice to neuroinflammatory injury from Mn, relative to females. To determine the role of estrogen (E2) in mediating sex-dependent vulnerability to Mn-induced neurotoxicity, we exposed transgenic mice expressing an NF-kB-driven enhanced green fluorescent protein (EGFP) reporter construct (NF-kB-EGFP mice) to Mn, postulating that supplementing male mice with E2 during juvenile development would attenuate neuroinflammatory changes associated with glia...

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The Linac Coherent Light Source (LCLS) will be the world's first x-ray free-electron laser (FEL). To ensure the vitality of FEL lasing, it is critical to preserve the high quality of the electron beam during acceleration and compression. The peak current and final energy are very sensitive to system jitter. To minimize this sensitivity, a longitudinal feedback system on the bunch length and energy is required, together with other diagnostics and feedback systems (e.g., on transverse phase space). Here, we describe a simulation framework, which includes a realistic jitter model for the LCLS accelerator system, the RF acceleration, structure wakefield, and second order optics. Simulation results show that to meet the tight requirements set by the FEL, such a longitudinal feedback system is mandatory.

International Nuclear Information System (INIS)

Methods for improving the sensitivity of scintillation cells for radon concentration measurements were studied with emphasis on improving light collection efficiency. This allows the length and hence the volume of the cell to be increased. Variables studied were choice of scintillator material, its method of application and thickness, length of cell, cell material, type and configuration of reflectors, choice of photomultipliers, and factors affecting background. Response from various areas of the cell surface was studied with an alphy source and with radon filling. Coating the window with phosphor was found to be counter-productive. The optimum results obtained were with the inside of the cell (other than the window) covered with a thick layer of ZnS(Ag), or with a thick layer of reflective material coated with a thin layer of phosphor. With it, a 10 cm diameter plexiglass cell can be extended to at least 50 cm length without difficulty from insufficient pulse ...

British Library Electronic Table of Contents (United Kingdom)

Analysis reproducibility and detection sensitivity of capillary electrophoresis (CE) are often questioned by applied scientists, which has hindered its application as a routine method. To address these issues, a simple, precise, and reproducible dynamic coating method was developed by applying carboxymethyl chitosan (CMC) dynamic coating on fused silica capillary. The proposed coating was accomplished by simply rinsing the capillary with CMC solution for 1?min in between runs, with no regeneration procedure or buffer additives needed. Electroosmotic flow could be well controlled by adjusting the pH of background electrolyte, and the adsorption of analytes onto the capillary inner wall was effectively eliminated. The main parameters of the coating condition were optimized, and extensive app...

Energy Technology Data Exchange (ETDEWEB)

Computer simulations of two-junction, concentrator tandem solar cell performance show that IR-sensitive bottom cells are required to achieve high efficiencies. Based on this conclusion, two novel concentrator tandem designs are under investigations: (1) a mechanically stacked, four-terminal GaAs/GaInAsP (0.95 eV) tandem, and (2) a monolithic, lattice-matched, three-terminal InP/GaInAs tandem. In preliminary experiments, terrestrial concentrator efficiencies exceeding 30% have been achieved with each of the above tandem designs. Methods for improving the efficiency of each tandem type are discussed. (orig.).

Energy Technology Data Exchange (ETDEWEB)

Southern California Gas Co.`s (SoCalGas) Energy Resource Center (ERC) in Downey, Calif. is a 45,000 ft{sup 2} (4,181 m{sup 21}) conference and education center created to help energy decision-makers find the most energy-efficient, cost-effective and environment-sensitive solutions to their energy requirements. The center has 36,000 ft{sup 2} (3,344 m{sup 2}) of remodeled space and 9,000 ft{sup 2} (836 m{sup 2}) of new space, all designed to showcase the latest energy-efficient and environment-sensitive technologies. The building is one of the 25 buildings in the US to be designated as Energy Star Showcase buildings by the US Environmental Protection Agency.

British Library Electronic Table of Contents (United Kingdom)

Field-annealed Co-based amorphous ribbon (Metglas? 2705M) with a meander structure is fabricated by MEMS technology and the giant magnetoimpedance (GMI) effects are studied at different magnetic fields and frequencies. The maximum longitudinal GMI ratio of the ribbon is 193.7% and the magnetic field sensitivity is 17.4%/Oe. The maximum GMI ratio of the meander ribbon is much larger than the single strip ribbon mainly due to the larger change ratio of inductance L. The sensitivity of an output U reach up to 10 V/A and U thermal fluctuation is less than 15 mV in the temperature range of ?20 to 40?C. This meander shape ribbon can be considered as a good candidate for the GMI-based sensor fabrication.

British Library Electronic Table of Contents (United Kingdom)

We investigated the magnet field dependence of the X-ray pulse height and the critical current of a Ti/Au bilayer TES micro-calorimeter. The pulse height was strongly affected by the magnetic field intensity applied perpendicularly to the TES surface. We found that the critical current at zero temperature, I c0, decreased by a factor of two by applying a magnet field of ?10??T. Our data are consistent with a TES sensitivity proportional to (I/I c0)?2/3, as predicted by the Ginzburg-Landau theory. This fact implies that the shape of the R?T curve of the TES is partly determined by the critical current of the superconductor. In order to make our TES microcalorimeters less sensitive to the external magnetic field, we fabricated devices equipped with on-chip magnetic shielding. One device has ...

British Library Electronic Table of Contents (United Kingdom)

The ensemble empirical mode decomposition (EEMD) can overcome the mode mixing problem of the empirical mode decomposition (EMD) and therefore provide more precise decomposition results. Wavelet neural network (WNN) possesses the advantages of both wavelet transform and artificial neural networks. This paper combines the merits of EEMD and WNN to propose an automated and effective fault diagnosis method of locomotive roller bearings. First, the vibration signals captured from the locomotive roller bearings are preprocessed by EEMD method and intrinsic mode functions (IMFs) are produced. Second, a kurtosis based method is presented and used to select the sensitive IMF. Third, time- and frequency-domain features are extracted from the sensitive IMF, its frequency spectrum and its envelope spe...

Energy Technology Data Exchange (ETDEWEB)

This report presents the results of an assessment of uranium in situ leach mining costs through the application of process engineering and discounted cash flow analysis procedures. A computerized costing technique was developed to facilitate rapid cost analyses. Applications of the cost model will generate mine life capital and operating costs as well as solve for economic production cost per pound U/sub 3/O/sub 8/. Conversely, rate of return may be determined subject to a known selling price. The data bases of the cost model were designed to reflect variations in Texas versus Wyoming site applications. The results of applying the model under numerous ore deposit, operating, well field, and extraction plant conditions for Texas and Wyoming are summarized in the report. Sensitivity analysis of changes in key project parameters have also been tested and are included.

International Nuclear Information System (INIS)

Coronary heart disease is the leading cause of death specially among elderly. Coronary angiography is the best diagnostic method in the patients, but is unfortunately an invasive procedure with its inherent risks. Myocardial perfusion scan is a noninvasive and sensitive method for evaluation of Coronary artery disease and is suggested by many investigators in recent years. In this study, 64 patients who had a Tc99m-MIBI SPECT myocardial perfusion study at our department, underwent coronary angiography within 4 months. Correlation of the methods revealed that SPECT Tc99m -MIBI had a high sensitivity and specificity in our hand, which is comparable with international findings.

Energy Technology Data Exchange (ETDEWEB)

Analyses of food-borne pathogens are of great importance in order to minimize the health risk for customers. Thus, very sensitive and rapid detection methods are required. Current conventional culture techniques are very time consuming. Modern immunoassays and biochemical analysis also require pre-enrichment steps resulting in a turnaround time of at least 24 h. Biomagnetic separation (BMS) is a promising more rapid method. In this study we describe the isolation of high affine and specific peptides from a phage-peptide library, which combined with BMS allows the detection of Salmonella spp. with a similar sensitivity as that of immunomagnetic separation using antibodies.

International Nuclear Information System (INIS)

The properties of a new commercial thermoluminescent dosimeter, CaSO4:Dy without a LiF binder (TLD-900) was studied for low-exposure measurements in diagnostic radiology. The former TLD-900 had a LiF binder (herein referred to as ''TLD-900/LiF''). The principle features of this dosimeter are its high sensitivity to low-energy radiation and its relatively low fading which permits measurements down to less than 2.6 X 10(-8) C kg (0.1 mR) with an accuracy better than 20%. The characteristics, annealing procedures, light sensitivity, energy response, reproducibility, and fading, of TLD-900 are discussed and compared with TLD-900/LiF. When the precautions presented in this paper are used, the dosimeters can be used for the measurement of x-ray exposures.

Energy Technology Data Exchange (ETDEWEB)

A large area Bragg curve spectroscopy (BCS) detector and a position sensitive parallel grid avalanche counter have been developed to study heavy ion reactions, such as inelastic excitations and few nucleon transfer reactions near the Coulomb barrier. Reasonably good resolutions have been achieved for energy, atomic number and angle. A theoretical investigation on the mass dependence of the Bragg peak signal from the BCS detector, shows that there is a negligible mass dependence related to the geometry of the detector. The mass number of the heavy ions which cannot be obtained by the above method, has been identified by detecting the corresponding characteristic gamma rays from the product nuclei with two large solid angle gamma ray detectors. (orig.)

British Library Electronic Table of Contents (United Kingdom)

Luminescent materials are widely used for imaging and sensing owing to their high sensitivity, rapid response and facile detection by many optical technologies. Typically materials must be chemically tailored to achieve intense, photostable fluorescence, oxygen-sensitive phosphorescence or dual emission for ratiometric sensing, often by blending two dyes in a matrix. Dual-emissive materials combining all of these features in one easily tunable molecular platform are desirable, but when fluorescence and phosphorescence originate from the same dye, it can be challenging to vary relative fluorescence/phosphorescence intensities for practical sensing applications. Heavy-atom substitution alone increases phosphorescence by a given, not variable amount. Here, we report a strategy for modulating ...

International Nuclear Information System (INIS)

Surface-sensitive UV photoelectron yield spectroscopy was employed to study electron acceptor levels at surfaces of chalcopyrite structure Cu-In-Se thin films. Surface Fermi level pinning was observed for Cu-rich films. Shallow acceptor levels ascribable to defects Cu_I_n and V_C_u were observed for near-stoichiometric and In-rich films respectively. (orig.).

Science.gov (United States)

Megasphaera elsdenii is a lactate-fermenting, obligately anaerobic bacterium commonly present in the gastrointestinal tracts of mammals, including humans. Swine M. elsdenii strains were previously shown to have high levels of tetracycline resistance (MIC = 64->256 micro g/ml) and to carry mosaic (re...

Energy Technology Data Exchange (ETDEWEB)

A method to deduce the 2 x 2 transport matrix for coupled heat and particle transport in Tokamaks is proposed. The method applies to perturbative experiments, and is based on a Fourier transform of the measured signals of temperature and density. By analyzing different linear combinations of temperature and density, the eigenvectors and eigenvalues of the transport matrix are determined. The method is tested for a number of illustrative cases using simulated data, and the sensitivity to noise on the signals is evaluated. (author).

Energy Technology Data Exchange (ETDEWEB)

Superconducting thin film particle detectors can be very attractive due to the low sensitivity to radiation damage. We describe the fabrication procedure and the characterization of Nb/Al bilayers as particle detectors. First steady and dynamical results are reported from tests of 5 MeV alpha-particle detection.

Energy Technology Data Exchange (ETDEWEB)

In the framework of the equivalence theorem the one-loop helicity amplitudes and cross section for the double Higgs production process {gamma}{gamma}{yields}HH are calculated. It is shown that the cross section is measurable at TeV {gamma}{gamma} colliders and is marginally sensitive to the triple-Higgs variation. (orig.).

CERN Document Server

The study of flavor changing neutrinos is a very active field of research. I will discuss the status of ongoing and near term experiments investigating neutrino properties at short distances from the source. In the next few years, the Double Chooz, RENO and Daya Bay reactor neutrino experiments will start looking for signatures of a non-zero value of the mixing angle $\\theta_{13}$ with much improved sensitivities. The MiniBooNE experiment is investigating the LSND anomaly by looking at both the $\

International Nuclear Information System (INIS)

An irradiation head with sample holders is described and measurement geometry is reported. Measurements were made for optimizing the distance between the source and the sample and for optimizing the sample diameter. The optimal distance between the source and the sample does not depend on the collimator diameter. The sample diameter should not exceed 30 - 35 mm. Sensitivity and detection limits were determined for Zn, Pb and Br and calibration curves were plotted. (M.D.) 6 figs., 2 tabs., 4 refs.

International Nuclear Information System (INIS)

Single-event burnout (SEB) sensitivity was tested for power MOSFET devices, JTMCS081 and JTMCS062, which were made in Institute of Microelectronics, Chinese Academy of Sciences, using californium-252 simulation source. SEB voltage threshold was found for devices under test (DUT). It is helpful for engineers to choose devices used in satellites. (authors)

DEFF Research Database (Denmark)

In male rodents, anogenital distance (AGD) provides a sensitive and continuous correlate of androgen exposure in the intrauterine environment and predicts later reproductive success. Some endocrine-disrupting chemicals can alter male reproductive tract development, including shortening AGD, in both rodents and humans. Whether AGD is related to semen quality in human is unknown.

UK PubMed Central (United Kingdom)

An antibody capture enzyme immunoassay (EIA) was adapted for the detection of immunoglobulin M (IgM) antibody to Sindbis (SIN) virus. Sera from humans with a febrile illness characterized by rash and...Full Text Available

International Nuclear Information System (INIS)

Results of the evaluation of the scattered radiation effect on the image of defects in examined products are given. The formula is suggested which characterizes the image of defects on a scintillation screen as well as accumulation factors are calculated by the Monte-Carlo method. Values of fluctuations of absorbed energy in the screen used for the evaluation of sensitivity are experimentally obtained. The effect of high-energy bremsstrahlung on the defect detection is analyzed.

UK PubMed Central (United Kingdom)

AimsRosiglitazone and fenofibrate, specific agonists of the peroxisome proliferator activated receptors-γ (PPARγ) and -α (PPARα),...Full Text Available

UK PubMed Central (United Kingdom)

We demonstrate that expression of the UGA1, CAN1, GAP1, PUT1, PUT2, PUT4, and DAL4 genes is sensitive to nitrogen catabolite repression. The expression of all these genes, with the exception of UGA1...Full Text Available

International Nuclear Information System (INIS)

Esters of dihydric alcohols with alkenylphosphonic or alkenylphosphinic acids which are polymerizable by free radicals are described. They are combined with polymer binders, in particular water-soluble polymers, and photoinitiators forming free radicals to give photopolymerizable mixtures which are suitable for the production of photoresists and printing plates. The mixtures display low heat-sensitivity and have long shelf lives. (author) 1 tab.

Energy Technology Data Exchange (ETDEWEB)

Cellulose raw materials costs must be considered in order to obtain a minimized hexose cost. In recognition of this fact, it may be economically advantageous to operate at less than maximum hexose concentration in the reactor and to recycle unreacted cellulose. The objective of this article is to optimize a cellulose-recycle reactor system for producing hexose at minimum cost. A sensitivity analysis of the important variables in the mathematical model of this system is also discussed.

International Nuclear Information System (INIS)

SGS-Thomson and CNES significantly hardened a power MOSFET transistor against heavy ions and cobalt 60 total dose. The influence of the major technological steps on the component radiation sensitivity has been analyzed. Then the optimization has been carried out, using booth computerized simulation and experimental data. (D.L.). 5 refs., 8 figs.

Wastenet

...) Abstract: Fluorescence microscopic imaging is widely used in biomedical research to study molecular and cellular processes in cell culture or tissue samples. This is motivated by the high inherent sensitivity of fluorescence techniques, the spatial resolution that compares favorably with cellular dimensions, the stability of the fluorescent labels used and the sophisticated strategies that have been developed for selectively labeling target molecules. More recently, two and ...

UK PubMed Central (United Kingdom)

Bovine tuberculosis is a major problem in many countries; hence, new and better diagnostic tools are urgently needed. In this work, we have tested ESAT6, CFP10, PE13, PE5, MPB70, TB10.4, and TB27.4...Full Text Available

International Nuclear Information System (INIS)

We report the homodyne detection of phase modulation sidebands induced on a laser beam by a coherently bunched electron beam. This provides a sensitive and nonperturbing measurement of complex Fourier time series components of the electron density. A proof-of-principle measurement of the microwave frequency component of electron density in a crossed-field device, which agrees well with a calculation of the same quantity, is reported.

International Nuclear Information System (INIS)

The aim of this study was to determine sensitivity and specificity of magnetic resonance angiography (MRA) for the assessment of durable occlusion of intracranial aneurysms with Guglielmi detachable coils (GDC) and to point out the influence of MRA results in re-intervention strategies. Forty-five patients with 54 aneurysms that were previously treated by endovascular occlusion with GDC were selected for this study. All patients underwent digital subtraction angiography (DSA) and MRA examinations on the same day. The time-of-flight MRA studies were performed on a 1-T scanner. The MRA images were first read by radiologists who were not aware of the DSA results. In a second consensus reading by the neuroradiologists who had performed all interventional procedures of this series, the decision was made as to whether re-treatment was necessary. The distribution of aneurysm sizes, configurations and treatment results were sufficient for an unbiased evaluation. The first ...

Energy Technology Data Exchange (ETDEWEB)

Analytical expressions for thermoluminescence (TL) dating based on the modified Zimmerman model were derived. The non-linear behaviour of TL sensitivity is reexamined and is found to be due to electron capturing competitions in both test-dose excitation and the readout stages. A curve fitting method is proposed to determine the paleodose for the additive dose dating method. The multiple activation technique is also investigated, from which the paleodose should be regarded as an upper limit.

UK PubMed Central (United Kingdom)

BackgroundThe large sensitivity, high reproducibility and essentially unlimited dynamic range of real-time PCR to measure gene expression in complex samples provides the opportunity...Full Text Available