Sample records for chief transport biochemistry

  1. Maltose Biochemistry and Transport in Plant Leaves

    Weber, Andreas P.M.


    Transitory starch builds up in photosynthesizing leaves during the day and is then degraded each night. It has recently been shown through mutant analysis and genetically engineered plants that transitory starch is required for maximal rates of photosynthesis, especially in high carbon dioxide atmospheres. Understanding the pathway by which carbon is exported from chloroplasts at night is limited. Previous work has shown that starch conversion to sucrose at night involves maltose export from chloroplasts. This pathway for carbon export from chloroplasts normally does not occur during the day. The regulation of maltose formation, the transporters that allow export of maltose from the chloroplast, and the cytosolic reactions by which maltose is converted to sucrose remain obscure. Genomic and biochemical approaches are proposed here to address maltose metabolism and transport. The research will cover three areas (1) how are hydrolytic and phosphorylytic starch degradation regulated, (2) how is maltose exported from chloroplasts, and (3) how is maltose converted to sucrose in the cytosol? It is expected that this research will lead to new insights about photosynthesis at high carbon dioxide levels, how carbon is partitioned in plants, and how partitioning can be altered to adapt plants to human needs.

  2. Using Adobe Flash Animations of Electron Transport Chain to Teach and Learn Biochemistry

    Teplá, Milada; Klímová, Helena


    Teaching the subject of the electron transport chain is one of the most challenging aspects of the chemistry curriculum at the high school level. This article presents an educational program called "Electron Transport Chain" which consists of 14 visual animations including a biochemistry quiz. The program was created in the Adobe Flash…

  3. Biochemistry Facility

    Federal Laboratory Consortium — The Biochemistry Facility provides expert services and consultation in biochemical enzyme assays and protein purification. The facility currently features 1) Liquid...


    Assessment of the health status of animals through measurement of cellular, biochemical, and macromolecular constituents in blood, secretions, and excretions has been variously referred to as clinical chemistry, clinical biochemistry, or clinical pathology. he genesis of this dis...

  5. Nutritional Biochemistry

    Smith, Scott M.


    This slide presentation reviews some of the effects that space flight has on humans nutritional biochemistry. Particular attention is devoted to the study of protein breakdown, inflammation, hypercatabolism, omega 3 fatty acids, vitamin D, calcium, urine, folate and nutrient stability of certain vitamins, the fluid shift and renal stone risk, acidosis, iron/hematology, and the effects on bone of dietary protein, potassium. inflammation, and omega-3 fatty acids

  6. Biochemistry engineering

    This deals with biochemistry engineering with nine chapters. It explains bionics on development and prospect, basics of life science on classification and structure, enzyme and metabolism, fundamentals of chemical engineering on viscosity, shear rate, PFR, CSTR, mixing, dispersion, measurement and response, Enzyme kinetics, competitive inhibition, pH profile, temperature profile, stoichiometry and fermentation kinetics, bio-reactor on Enzyme-reactor and microorganism-reactor, measurement and processing on data acquisition and data processing, separation and purification, waste water treatment and economics of bionics process.

  7. Symposium 19: The contributions of the Department of Biochemistry/USP towards Biochemistry teaching

    Bayardo Baptista Torres


    Full Text Available K-Education(Portuguese Chair: V. Trindade Bayardo Torres; Clovis Wannmacher; Denise MacedoThe contributions of the Department of Biochemistry/USP towards Biochemistry teaching.O ensino de Bioquímica nos últimos 20 anosBayardo B. TorresDepartamento de Bioquímica, Instituto de Química, USP. São Paulo, Brazil.Among the contributions of the Department of Biochemistry/USP one must recall:1. Winter school for graduate studentsThis course, now at the ninth edition, is intended for students in the final stage of their Masters or PhD in Biochemistry or related areas from any institution of higher education.Modern and important techniques are offered as possible support to help the student’s projects.2. Summer courses for undergraduate studentsThe Department offers every year, since 1999, complementary courses for undergraduate students to extend their knowledge in biochemical subjects not ordinarily treated in introductory courses. Some examples:Plant Molecular Biology, Biochemistry and Diseases, Biochemistry of Mind, Biochemistry of Ageing, Cancer Biochemistry, Nutrition and Sports, Biochemistry of Beauty, Biochemistry of the Envenomation Response, etc.3. Summer courses for high school teachers. Some examples:Biochemistry of Nutrition, DNA – Techniques and Applications, Biochemistry in the kitchen.4. Software developmentMany software for biochemistry teaching/learning were developed and are freely available at the Biblioteca Digital de Ciências []. Some examples:Oxygen consumption by mitochondria, Muscle contraction, Electron transport chain and oxidative phosphorylation, Free radicals, Enzyme kinetics, cAMP signalization, Interactive study of protein structure, Leptin, Insulin and Obesity.5. A Biochemistry textbook. 

  8. Useful Demonstrations for a Medial Biochemistry Course.

    Ragatz, Barth H.; Modrak, Gina


    Describes six demonstrations used in a medical biochemistry course. These demonstrations focus on: (1) platelet aggregometry; (2) ion-transporting antibiotics; (3) glycosylated hemoglobin; (4) molecular models; (5) serum preparation; and (6) bioluminescence. (JN)

  9. Reproduction, Physiology and Biochemistry

    This chapter focuses on the reproduction, physiology, and biochemistry of the root-knot nematodes. The extensive amount of information on the reproduction and cytogenetics of species of Meloidogyne contrasts with the limited information on physiology, biochemistry, and biochemical pathways. In commo...

  10. Reproduction, physiology and biochemistry

    This chapter summarizes fundamental knowledge and recent discoveries about the reproduction, physiology and biochemistry of plant-parasitic nematodes. Various types of reproduction are reviewed, including sexual reproduction and mitotic and meiotic parthenogenesis. Although much is known about the p...

  11. Narrator-in-Chief

    Herron, Mark A.

    The dissertation Narrator-in-Chief: The Narrative Rhetoric of Barack Obama seeks to show how the concept of “narrative” can be used in rhetorical criticism of presidential speeches, particularly when considering the speeches and the biographical text, Dreams from My Father (1995), of Barack Obama...

  12. Too Many Chiefs

    Joseph Schumpeter


    @@ When it comes to job titles, we live in an age of rampant inflation. Everybody you come across seems to be a chief or president of some variety. Title inflation is producing its own vocabulary: "uptitling" and "title-fluffing". It is also producing technological aids. One website provides a simple formula: just take your job title, mix in a few grand words, such as "global", "interface" and "customer", and hey presto.

  13. Abstracts of the 27. Annual meeting of the Brazilian Society on Biochemistry and Molecular Biology

    This meeting was about biochemistry and molecular biology. It was discussed topics related to bio energetic, channels, transports, biotechnology, metabolism, cellular biology, immunology, toxicology, photobiology and pharmacology

  14. Abstracts of the 26. Annual meeting of the Brazilian Society on Biochemistry and Molecular Biology

    This meeting was about biochemistry and molecular biology. It was discussed topics related to bio energetic, channels, transports, biotechnology, metabolism, cellular biology, immunology, toxicology, photobiology and pharmacology

  15. Chief Editors’ Introduction

    Kerry Carrington


    Full Text Available It has been a great year for the journal:  our most successful ever. This edition marks three years of publication of the International Journal for Crime, Justice and Social Democracy. In 2015 the journal was selected for inclusion into Scopus and Web of Science data bases. This is a terrific success story and testimony to the high quality of the articles, the editorship, the reviewing and the international readership of the journal. We are grateful as ever to our distinguished International Editorial Board and all our reviewers who are anonymous to readers and authors due to the norms of blind peer reviewing. We also thank the out-going foundational co-editor-in-chief Reece Walters for his efforts in making this journal the success it is. The journal has now surpassed 150,000 abstract views and 100,000 full PDF downloads. This journal is one of only a few in the world of criminology to support fully on-line free-to-download articles, and to promote creative commons copyright: that is, authors’ rights to reproduce their own material. We support the democratisation of knowledge and are delighted to be leaders in high quality international journal publishing.Download the PDF file here for the Chief Editors’ introduction to this issue and be motivated by the eclectic and impressive range of topics offered by our contributors to read further.

  16. Thiol biochemistry of prokaryotes

    Fahey, Robert C.


    The present studies have shown that GSH metabolism arose in the purple bacteria and cyanobacteria where it functions to protect against oxygen toxicity. Evidence was obtained indicating that GSH metabolism was incorporated into eucaryotes via the endosymbiosis giving rise to mitochrondria and chloroplasts. Aerobic bacteria lacking GSH utilize other thiols for apparently similar functions, the thiol being coenzyme A in Gram positive bacteria and chi-glutamylcysteine in the halobacteria. The thiol biochemistry of prokaryotes is thus seen to be much more highly diversified than that of eucaryotes and much remains to be learned about this subject.

  17. Biochemistry interview transcript 3

    Tonkin, Suzanne


    A series of personal interviews were carried out following on from the Project StORe questionnaire. Of the original 46 Biochemistry respondents, 11 indicated that they would be willing to be interviewed. Each potential interviewee was contacted during May 2006 and 10 interviews in total were conducted during June and July 2006. Of these, 5 were telephone interviews and 5 were conducted face-to-face. Each interview was with a single individual apart from the final face-to-face interview, which...

  18. Biochemistry interview transcript 9

    Tonkin, Suzanne


    A series of personal interviews were carried out following on from the Project StORe questionnaire. Of the original 46 Biochemistry respondents, 11 indicated that they would be willing to be interviewed. Each potential interviewee was contacted during May 2006 and 10 interviews in total were conducted during June and July 2006. Of these, 5 were telephone interviews and 5 were conducted face-to-face. Each interview was with a single individual apart from the final face-to-face interview, which...

  19. Biochemistry interview transcript 4

    Tonkin, Suzanne


    A series of personal interviews were carried out following on from the Project StORe questionnaire. Of the original 46 Biochemistry respondents, 11 indicated that they would be willing to be interviewed. Each potential interviewee was contacted during May 2006 and 10 interviews in total were conducted during June and July 2006. Of these, 5 were telephone interviews and 5 were conducted face-to-face. Each interview was with a single individual apart from the final face-to-face interview, which...

  20. Biochemistry interview transcript 10

    Tonkin, Suzanne


    A series of personal interviews were carried out following on from the Project StORe questionnaire. Of the original 46 Biochemistry respondents, 11 indicated that they would be willing to be interviewed. Each potential interviewee was contacted during May 2006 and 10 interviews in total were conducted during June and July 2006. Of these, 5 were telephone interviews and 5 were conducted face-to-face. Each interview was with a single individual apart from the final face-to-face interview, which...

  1. Biochemistry interview transcript 5

    Tonkin, Suzanne


    A series of personal interviews were carried out following on from the Project StORe questionnaire. Of the original 46 Biochemistry respondents, 11 indicated that they would be willing to be interviewed. Each potential interviewee was contacted during May 2006 and 10 interviews in total were conducted during June and July 2006. Of these, 5 were telephone interviews and 5 were conducted face-to-face. Each interview was with a single individual apart from the final face-to-face interview, which...

  2. Biochemistry interview transcript 1

    Tonkin, Suzanne


    A series of personal interviews were carried out following on from the Project StORe questionnaire. Of the original 46 Biochemistry respondents, 11 indicated that they would be willing to be interviewed. Each potential interviewee was contacted during May 2006 and 10 interviews in total were conducted during June and July 2006. Of these, 5 were telephone interviews and 5 were conducted face-to-face. Each interview was with a single individual apart from the final face-to-face interview, which...

  3. Biochemistry interview transcript 8

    Tonkin, Suzanne


    A series of personal interviews were carried out following on from the Project StORe questionnaire. Of the original 46 Biochemistry respondents, 11 indicated that they would be willing to be interviewed. Each potential interviewee was contacted during May 2006 and 10 interviews in total were conducted during June and July 2006. Of these, 5 were telephone interviews and 5 were conducted face-to-face. Each interview was with a single individual apart from the final face-to-face interview, which...

  4. Biochemistry interview transcript 2

    Tonkin, Suzanne


    A series of personal interviews were carried out following on from the Project StORe questionnaire. Of the original 46 Biochemistry respondents, 11 indicated that they would be willing to be interviewed. Each potential interviewee was contacted during May 2006 and 10 interviews in total were conducted during June and July 2006. Of these, 5 were telephone interviews and 5 were conducted face-to-face. Each interview was with a single individual apart from the final face-to-face interview, which...

  5. Biochemistry interview transcript 7

    Tonkin, Suzanne


    A series of personal interviews were carried out following on from the Project StORe questionnaire. Of the original 46 Biochemistry respondents, 11 indicated that they would be willing to be interviewed. Each potential interviewee was contacted during May 2006 and 10 interviews in total were conducted during June and July 2006. Of these, 5 were telephone interviews and 5 were conducted face-to-face. Each interview was with a single individual apart from the final face-to-face interview, which...

  6. Biochemistry interview transcript 6

    Tonkin, Suzanne


    A series of personal interviews were carried out following on from the Project StORe questionnaire. Of the original 46 Biochemistry respondents, 11 indicated that they would be willing to be interviewed. Each potential interviewee was contacted during May 2006 and 10 interviews in total were conducted during June and July 2006. Of these, 5 were telephone interviews and 5 were conducted face-to-face. Each interview was with a single individual apart from the final face-to-face interview, which...

  7. Towards quantitative biochemistry: research and reports in biochemistry



    Full Text Available Nikolay V DokholyanDepartment of Biochemistry and Biophysics, University of North Carolina, School of Medicine, Chapel Hill, NC, USASince the mid twentieth century the field of biochemistry has evolved significantly (Figure 1. Advances made in the fields of structural, chemical, and systems biology, physics, and computation have shaped the new field of biochemistry such that the emphasis became the cellular-wide view of molecular life at the atomic scale. The principal paradigm in the field shifted from focusing on a single or a few biological molecules to focusing on their cellular- and intracellular-wide networks. This shift has resulted in more interdisciplinary approaches to biochemical research, which nowadays combines techniques and strategies from a broad range of fields. The evolution of the field of biochemistry resulted in closer connections to other fields, such as medicinal chemistry, physiology, and medicine. Biochemistry is also one of the central components of the emerging translational medicine paradigm.

  8. Chapter IV: ultrafast biochemistry

    Chergui, M. [Swiss Federal Institute of Technology (EPFL), Lausanne (Switzerland); Kjelstrup, S. [Norwegian University of Science and Technology (NTNU), Trondheim (Norway); Meuwly, M. [Universitaet Basel, Basel (Switzerland); Schuler, B. [University of Zuerich (ETH), Zurich (Switzerland); Thor, J. van [Imperial College London (IC), London (United Kingdom)


    The whole report issued by the Paul Scherrer Institute (PSI) in Switzerland takes a look at the scientific opportunities offered by the institute's SwissFEL X-ray Laser facility. In this sixth part, initial events and fluctuations in biochemical processes at the atomic scale are discussed. Sub-nanosecond processes are fundamental to biochemistry and will be accessible to the ultra-short pulses of the SwissFEL. Time and length scales of biochemical reactions are discussed, as is the photo-initiation of biochemical processes. Time-resolved measurement techniques are looked at. Fluorescence resonant energy transfer is discussed. As an example, the photo cycle of bacteriorhodopsin is examined. The dynamics of protein folding and catalytic action are also looked at. Mesoscopic non-equilibrium thermodynamics is discussed

  9. [Research activity in clinical biochemistry

    Jorgensen, H.L.; Larsen, B.; Ingwersen, P.;


    BACKGROUND: Quantitative bibliometric measurements of research activity are frequently used, e.g. for evaluating applicants for academic positions. The purpose of this investigation is to assess research activity within the medical speciality of Clinical Biochemistry by comparing it with a matched...... Clinical Biochemistry, 57 fulfilled the inclusion criteria. Each of these 57 was matched according to medical title with two randomly chosen specialists from other specialities, totaling 114. Using Medline and the Web of Science, the number of publications and the number of citations were then ascertained....... RESULTS: 25% of the 11,691 specialists held a PhD degree or doctoral degree, DMSci, (Clinical Biochemistry: 61%). The 171 specialists included in the study had 9,823 papers in Medline and 10,140 papers in the Web of Science. The number of Medline papers per specialist was 71 for Clinical Biochemistry...

  10. 29 CFR 457.16 - Chief, DOE.


    ... 29 Labor 2 2010-07-01 2010-07-01 false Chief, DOE. 457.16 Section 457.16 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR STANDARDS OF CONDUCT GENERAL Meaning of Terms as Used in This Chapter § 457.16 Chief, DOE. Chief, DOE means the Chief of the...

  11. Biochemistry of Mitochondria

    Filiz Koc


    Full Text Available Mitochondria are energy source of cells. They have external and internal membranes, cristas and matrix. External membranes consist of specialized transport proteins. They have monoamine oxidase and citokrome-c reductase which both play role in KREBS cycle as catalyst and many enzymes which are necessary for phospholipid and phosphoric acid synthesis. Enzymes of electron transport chain and oxidative phosphorylation are located in the internal membranes. Also, here, there are transport systems for specific substances, such as ATP, ADP, P1, pyruvate, succinate, malate, citrate, and -ketoglutarate . Matrix; having gel-like consistency, contains a large number of enzymes. [Archives Medical Review Journal 2003; 12(0.100: 1-13


    R.M. Lima


    Full Text Available The revolution  in information  technology  has included the INTERNET to the available  resources for biochemical  education.  There  is a great  deal of biochemical  information, and  the  amount is increas- ing rapidly,  indeed  exponentially.  The  aim of this work is to analyze  the  biochemical  issues cellular respiration, photosynthesis and membrane  transport available  in web pages, taking  into account con- tents  quality,  trustworthiness and effectiveness. Firstly  1st secondary level students were inquired by a questionnaire on their use of INTERNET resources.  More then 80 percent of them were regular users. The  results  confirm the  already  known  potential of INTERNET in education.  Fourteen sites  were analyzed  regarding  to contents, presence  of bibliographical, references,  authorship, titles  responsible and adequacy  to the target public.  In relation  to contents, presence of conceptual  errors, illustrations and other  stimulatory elements  were analyzed.  The great  majority  did not mention  bibliographic  ref- erences and target public.  Less than  half divulged responsible  names and/or their  graduation status. Some sites contained critical  conceptual  errors,  as the mention  of, as examples:  during  the cell active transport process, of energy (ATP waste (desperdício by the cell; the yeast is a pluricellular  fungal; and  the  oxygen is essential  for anaerobic  respiration.  However,  one of the  sites,  where  such  errors were found, was the only one to mention  enzymes and regulation  steps of cellular respiration. Half of the sites present identical  texts  and figures. None of the analyzed  sites thus  was considered excellent. Our data  strenghthen the need for rigorous evaluation concerning of scholarly research  of biochemical theme  on the web.INTERNET ASSISTED LEARNING OF  BIOCHEMISTRY

  13. Soil Microbiology, Ecology, and Biochemistry

    The 4th edition of Soil Microbiology, Ecology, and Biochemistry Edited by Eldor Paul continues in the vein of the 3rd edition by providing an excellent, broad-reaching introduction to soil biology. The new edition improves on the previous by providing extensive supplementary materials, links to outs...

  14. Commentary: Biochemistry Re-Natured

    White, Harold B.


    In his last commentary on "Biochemistry Denatured," this author dealt with his perception that college students today have spent too little of their childhood years playing outside in nature and as a consequence have not learned basic things about the world from personal experience. This "nature-deficit disorder" removes many opportunities for…

  15. Does breast feeding influence liver biochemistry?

    Jørgensen, Marianne Hørby; Ott, Peter; Juul, Anders;


    It is assumed that early feeding can affect liver biochemistry because breast-fed infants have a higher risk of hyperbilirubinemia than formula-fed infants. The authors sought to determine how feeding mode affected liver biochemistry in healthy term infants.......It is assumed that early feeding can affect liver biochemistry because breast-fed infants have a higher risk of hyperbilirubinemia than formula-fed infants. The authors sought to determine how feeding mode affected liver biochemistry in healthy term infants....

  16. Metabolism and biochemistry in hypogravity

    Leach, Carolyn S.


    The headward shift of body fluid and increase in stress-related hormones that occur in hypogravity bring about a number of changes in metabolism and biochemistry of the human body. Such alterations may have important effects on health during flight and during a recovery period after return to earth. Body fluid and electrolytes are lost, and blood levels of several hormones that control metabolism are altered during space flight. Increased serum calcium may lead to an increased risk of renal stone formation during flight, and altered drug metabolism could influence the efficacy of therapeutic agents. Orthostatic intolerance and an increased risk of fracturing weakened bones are concerns at landing. It is important to understand biochemistry and metabolism in hypogravity so that clinically important developments can be anticipated and prevented or ameliorated.

  17. Biochemistry: from supermarket to laboratory

    F. R. Freitas-Rego; Pereira, M.G.; S. O. Loureiro; M. T. de Santana; R. G. Garrido; F. de S.R.G Garrido


    After new campi as Instituto Multidisciplinar em Saúde (IMS/UFBA) startedworking, it was necessary to develop practical classes using domestic reagents atBiochemistry to Pharmacy (IMS078). Firstly, students visited a supermarket to readnutritional information at label and select possible products to be used in class. Moreover,chemical processes and fermentation were discussed as different foods and drinks wereanalysed. Some food were token to laboratories so that biomole cules qualitative ana...

  18. Gender Performance Differences in Biochemistry

    Rauschenberger, Matthew M.; Sweeder, Ryan D.


    This study examined the historical performance of students at Michigan State University in a two-part biochemistry series Biochem I (n = 5,900) and Biochem II (n = 5,214) for students enrolled from 1997 to 2009. Multiple linear regressions predicted 54.9-87.5% of the variance in student from Biochem I grade and 53.8-76.1% of the variance in…


    Aleksandra KOLESNIKOVA


    Full Text Available The paper considered a trend showing the women who strive to get leading posts increase in numbers every year. However, on the other hand, stereotypes persist on women as a staffer unable to perform the executive du-ties. The study examined the working men and women who told their mind on an image of a chief woman; how the image correlated to a concept of an ideal woman. The authors have carried out a qualitative survey thereto with the sentence completion technique applied.

  20. Leadership certificate program for chief residents

    Jeffrey E. Pettit


    Full Text Available Background. Chief resident leadership development programs need to be more than a one/two day symposium to sustain leadership development. This article describes the structure and outcomes for an eight-month leadership development program for chief residents conducted over the past three years at the University of Iowa Hospitals & Clinics (UIHC, USA. Additionally, it provides keys to success and logistical issues for any institution that is considering a similar program. Innovation. Current chiefs must formally apply in late August. Sessions are held on the second Tuesday of each month for two hours. Facilitators guide each session in such a manner that they allow participants to do most of the discussion. Facilitators also provide opportunities for insight from other chiefs, and provoke deeper understanding of behaviors or thoughts. Eight topics are covered during the year with intersession assignments. Additionally, chiefs are required to attend 75% of the sessions, develop a leadership philosophy, and conduct some type of leadership presentation within their own department. Evaluation. Each year since 2010, the number of participating chiefs has risen (6, 9, 9. Evaluation data indicates a marked increase in before and after leadership knowledge and self-awareness. Additionally, chiefs have reported positive behavioral impacts regarding their leadership. Chiefs are the best advertising source for the program. Conclusions. The leadership program continues to evolve and evaluation results indicate that the content is instructive and the format is supportive for participants. Most chiefs recommend it highly for future chiefs.

  1. Biochemistry

    The contributions of the group consist of six reports. The first is concerned with recent developments in the isolation and characterization of subcellular components of mammalian cells: the inhibition by imipramine of digitonin-induced lysis of mitochondrial membranes; age-dependent changes in mitochondrial sedimentability; peroxisomal enzymes; and collaborative studies on near-uv effects on bacterial respiration, radiation effects on mouse heart mitochondria, and toxicity and distribution of liposome-encapsulated drugs. Plant physiology is the theme of the next two reports. The first describes progress in a NASA-supported program on the involvement of organelles, especially dictyosomes, in the georesponse of roots, and the second covers work principally supported by ERDA on the interaction of light and gravity on differential growth of corn roots. Progress in liposome encapsulation of drugs is presented in three contributions. The first deals with studies on the toxicity, distribution, therapeutic action, and mechanism of encapsulated cancer chemotherapeutic agents; the second with morphologic studies, based principally on electron microscopy; and the third with alteration of liposomal surface properties by varying the lipid composition, in order to modify tissue distribution

  2. Insect Biochemistry Goes to School .

    Leonardo R. Cunha; Cecília Cudischevitch; Willy Jablonka; Alan de Brito; Mário A. Silva-Neto


    Many arthropods feed on vertebrate blood and eventually transmit diseases to the human being. Ordinary citizens are continuously exposed to vectors of major diseases and thus prone to contamination. In the present study we have evaluated a new approach regarding the basic biochemistry mechanism that regulates thebiology of Triatominaes, well known as vectors of Chagas Disease. We have used a comic book "Carlos Chagas: 100 years of the discovery of a hero", produced by researchers at our labor...

  3. 7 CFR 2.29 - Chief Economist.


    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Chief Economist. 2.29 Section 2.29 Agriculture Office... Economist. (a) The following delegations of authority are made by the Secretary of Agriculture to the Chief Economist: (1) Related to economic analysis. (i) Coordinate economic analyses of, and review...

  4. From editor-in-chief

    Fokin V.F.


    Full Text Available Editor-in-chief (C. 3 Dear readers and authors of the journal "Asymmetry"! Summer and beginning of autumn is traditionally not only the time for vacations, but also a variety of conferences. I participated in the 21st world Congress of neurology held in late September in Vienna. In his many papers were devoted to various, for the most part, practically important issues neurology. While the theoretical aspects of neurology, one way or another, was also highlighted at the Congress, including the issues of asymmetry. I would like to highlight two areas. First of all, pay attention to enchanting lecture Nobel laureate E. Candela "Vienna and the age of insight", in which E. Kandel told about the influence of art Nouveau on the work of Z. Freud in psychoanalysis. (More about this can be found in the Facebook log "Asymmetry" - In other words, it was about the translation of non-verbal images in some logical designs and ideas. Unfortunately, these research tasks are still in the field of theoretical developments. Another direction was reflected in the plenary lecture M Chilca "Stroke and autonomic nervous system. The lecture was directly associated survival after stroke in the basin of the carotid arteries with damage to the cortical representation of the autonomic nervous system, which, as you wrote about it, including, and in our magazine, also asymmetrically. When left hemispheric stroke the medial prefrontal cortex and the insulin are observed less pronounced change in the characteristics of the cardiovascular system, compared to the same right hemispheric strokes. This lecture aroused great interest. Thus, we see the development of the research two types of asymmetries, which in some cases are conducted in parallel: cognitive and autonomic asymmetry. "Vegetative" asymmetry is much less studied, although its contribution to the clinic, sports medicine and pedagogy can be very serious. I wish the readers of the

  5. Instructional Software for Biochemistry Education

    Marson Guilherme Andrade


    Full Text Available In the last decades the world has witnessed a revolution in the expansion and access to knowledge, whi-ch has dramatically changed the relationship between labor and production. According to UNESCO(United Nations Educational, Scientical and Cultural Organization and ILO (International LaborOrganization, in the of information it is fundamental that Higher Education Institutes educate pro-fessionals capable to update their knowledge in the course of professional life. The so-called life-longlearning s pointed out as a request for creating and maintaining jobs, and for supporting the develop-ment of nations as well. In such context, Biochemistry is a eld of knowledge which has outstandinglyexpanded its boundaries. Preparing the next generation of biochemists for the age of informationrequires the development of cognitive skills as an essential educational goal concerning graduationcourses, which have been historically limited to the exposition of contents. The achievement of suchobjective depends on many factors, including the development of suitable instructional materials thatcan improve the teaching and learning experience. This conference deals with the development ofinstructional software at the crossroad of Educational research, Informatics and Biochemistry. Theinvestigative approach leading to the development and improvement of instructional software for Bi-ochemical education will be discussed on the basis of the following issues: i motivating questionsto software development - teaching and learning problems; ii development of digital content: speci-c content, interface and interactivity; iii evaluation of the software s instructional eciency; ivexamples of softwares which have been conceived according to the discussed methodology.

  6. 78 FR 50052 - Chief of Engineers Environmental Advisory Board; Meeting


    ... Department of the Army; Corps of Engineers Chief of Engineers Environmental Advisory Board; Meeting AGENCY... the forthcoming meeting. Name of Committee: Chief of Engineers Environmental Advisory Board (EAB... the Chief of Engineers on environmental policy, identification and resolution of environmental...

  7. Searching for Alien Life Having Unearthly Biochemistry

    Jones, Harry


    The search for alien life in the solar system should include exploring unearth-like environments for life having an unearthly biochemistry. We expect alien life to conform to the same basic chemical and ecological constraints as terrestrial life, since inorganic chemistry and the laws of ecosystems appear to be universal. Astrobiologists usually assume alien life will use familiar terrestrial biochemistry and therefore hope to find alien life by searching near water or by supplying hydrocarbons. The assumption that alien life is likely to be based on carbon and water is traditional and plausible. It justifies high priority for missions to search for alien life on Mars and Europa, but it unduly restricts the search for alien life. Terrestrial carbon-water biochemistry is not possible on most of the bodies of our solar system, but all alien life is not necessarily based on terrestrial biochemistry. If alien life has a separate origin from Earth life, and if can survive in an environment extremely different from Earth's, then alien life may have unearthly biochemistry. There may be other solvents than water that support alien life and other elements than carbon that form complex life enabling chain molecules. Rather than making the exploration-restricting assumption that all life requires carbon, water, and terrestrial biochemistry, we should make the exploration-friendly assumption that indigenous, environmentally adapted, alien life forms might flourish using unearthly biochemistry in many places in the solar system. Alien life might be found wherever there is free energy and a physical/chemical system capable of using that energy to build living structures. Alien life may be discovered by the detection of some general non-equilibrium chemistry rather than of terrestrial biochemistry. We should explore all the potential abodes of life in the solar system, including those where life based on terrestrial biochemistry can not exist.

  8. From editor-in-chief

    Fokin V.F.


    Full Text Available Editor-in-chief (C. 3 Dear readers and authors of the journal "Asymmetry"! The second issue of "Asymmetry" was released in the height of summer, when seemingly every activity should go away. However, judging by the articles received by the editors in the summer with our authors is the most productive period. We strive to work published in the journal "Asymmetry", were available to a wide circle of readers. Recently, our articles were indexed in the same database - Directory of Open Access Journals (DOAJ, which contains all world magazines related to so-called open access journals Open access”. The popularity and various indexes in our time, of course, important as one of the possible tools of social adaptation, but it cannot be the purpose of the research. Now study the problem of asymmetry is in the hands of poorly interrelated scientific workers, which, depending on personal history and possibilities, they do some research. It seems to me that we lack a broad and friendly discussions, which could be useful to many scientists. Conference presentations because of their dense format rarely permit a full discussion of each message. Therefore, we plan to start a series of seminars, web conferences, where after the main speech everyone will be able to discuss a submission is made. I must say that before perestroika in the brain Institute of the Russian Academy of medical Sciences existed multidisciplinary seminar on the issues of lateralization, which attracted the attention of the scientific community. The present proposal is, in fact, the development of the same idea using the new technical possibilities. Anyone wishing to participate in such seminars, regardless of their residence can be sent to the editorial address their applications. And last, after discussion with colleagues, we decided to celebrate annually the one article, published in the journal "Asymmetry" medal of Brock. It will work, which attains the maximum number of votes from our

  9. Molecular structure of actinides in biochemistry

    In case of internal contamination, drugs used for decorporation are scarce and do not act very specifically. For instance the sole de-corporating drug recommended for plutonium decontamination is a water-soluble ligand named DTPA (Diethylene-Triamino-Pentaacetate). The transport of DTPA to its organ-target and its bio-availability on the spot are not satisfactorily understood. The conventional method to develop new ligands is based on molecular approaches but it is not sufficient. A new method that combines methods from structural biochemistry with methods of bio-inorganic chemistry and with methods from physico-chemistry (particularly X-ray absorption spectroscopy) is so far the best way to understand molecular speciation and to detail the local arrangement of atoms around a cation for instance, which are valuable information to understand the behaviour of a ligand. EXAFS (Extended X-ray Absorption Fine structure Spectroscopy) measurements suggest that during the formation of a complex involving an actinide (An) and a ligand, the inter-atomic distance An-O decreases when the atomic number of the cation increases while it is the reverse in the case of An-N

  10. Research chief wants to make science matter

    König, R


    The new research chief of the European Union, Phillippe Busquin wants to move science into the heart of EU decision-taking. He would like to make European research more 'cohesive, focused, mobile and multilateral' (2 pages).

  11. Letter from Editors-in-Chief

    Kwok-Fai So; Xiao-Ming Xu


    @@ Dear readers, We would first like to take this opportunity to wish you all a very happy, prosperous, and productive New Year! We are honored and enthusiastic to begin the year as the new Editors-In-Chief of Neural Regeneration Research (NRR). Through the leadership and scholarship of founding Editor-In-Chief, Professor Qunyuan Xu, NRR has become a successful and respected peer-reviewed intemational journal focusing exclusively on the exciting field of neural regeneration research.

  12. Leadership certificate program for chief residents

    Jeffrey E. Pettit; Wilson, Mark C.


    Background. Chief resident leadership development programs need to be more than a one/two day symposium to sustain leadership development. This article describes the structure and outcomes for an eight-month leadership development program for chief residents conducted over the past three years at the University of Iowa Hospitals & Clinics (UIHC), USA. Additionally, it provides keys to success and logistical issues for any institution that is considering a similar program. Innovation. Curr...

  13. Insect Biochemistry Goes to School .

    Leonardo R. Cunha


    Full Text Available Many arthropods feed on vertebrate blood and eventually transmit diseases to the human being. Ordinary citizens are continuously exposed to vectors of major diseases and thus prone to contamination. In the present study we have evaluated a new approach regarding the basic biochemistry mechanism that regulates thebiology of Triatominaes, well known as vectors of Chagas Disease. We have used a comic book "Carlos Chagas: 100 years of the discovery of a hero", produced by researchers at our laboratory. The main concepts presented include: neurochemistry of insect olfaction, hemostasis, blood digestion, redox balance to mention some. The material was applied between 60 pupils of theseventh year of elementary school. The work is divided into two phases: an assessment of the concepts that thestudents bring their experiences into the classroom by producing conceptual maps followed by the intervention with the comic and production ofnew conceptual maps under the influence of activity with the material. Analysis of 18conceptual maps obtained from 06 different groups at three different points revealedthat the average score 07 at the beginning of theevaluation went to an average of 45 at the end of the study. This result suggests that a change in the approach of content can give encouragement to students to better develop the theme of contributing to a proper process of conceptual change.

  14. 12 CFR 1710.17 - Certification of disclosures by chief executive officer and chief financial officer.


    ... ENTERPRISE OVERSIGHT, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SAFETY AND SOUNDNESS CORPORATE GOVERNANCE Corporate Practices and Procedures § 1710.17 Certification of disclosures by chief executive officer...

  15. 7 CFR 2.70 - Deputy Chief Economist.


    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Deputy Chief Economist. 2.70 Section 2.70 Agriculture... GENERAL OFFICERS OF THE DEPARTMENT Delegations of Authority by the Chief Economist § 2.70 Deputy Chief Economist. Pursuant to § 2.29, the following delegation of authority is made by the Chief Economist to...

  16. 7 CFR 1700.27 - Chief of Staff.


    ... Administrator in developing and planning agency program initiatives. The Chief of Staff is responsible for... 7 Agriculture 11 2010-01-01 2010-01-01 false Chief of Staff. 1700.27 Section 1700.27 Agriculture... GENERAL INFORMATION Agency Organization and Functions § 1700.27 Chief of Staff. The Chief of Staff...

  17. Chief Constable's annual report 1986

    The nature of the UKAEA constabulary, its personnel, administration and training, are all covered in this report. The crimes recorded at the UKAEA and BNFL sites are analysed. Traffic problems, transport and communications are covered. Miscellaneous police functions (eg lost property), the constabulary social activities and visitors to nuclear establishments are mentioned. The report ends with a policy statement on the aims and objectives of the constabulary. The report covers 1986. (U.K.)


    H. G. Cordeiro


    Full Text Available INTRODUCTION: The economic and social development of Brazil in the last decade has contributed to the installation of new graduate and undergraduate programs, as are the case with bachelor degrees in Biochemistry at UFV, UFSJ and UEM. These graduates are prepared to work in industry, research institutes and universities in areas of knowledge involving Biochemistry and Molecular Biology. This is happening in developed countries since the first half of the last century, surprising and late is the implementation of bachelor of Biochemistry in Brazil. OBJECTIVES: The aim of this study was to perform a comparative analysis of the Bachelor in Biochemistry in Brazil from the perspective of the main difficulties of implementing and courses maintenance. MATERIAL AND METHODS: This is a descriptive research with a qualitative approach. Interviews were conducted with undergraduate students, graduates, professors, staff and managers from bachelor degrees in Biochemistry at UFV, UFSJ and UEM. The sampling procedure was non probabilistic for judgment (choice of the subjects involved and interested in the course of biochemistry to undergraduate students, graduates, professors and staff and non probabilistic for convenience to managers. The qualitative assessment to depict the representative keywords was performed using words cloud by WordleTM. RESULTS: The study included 5 managers, 24 professors, 12 staff, 25 undergraduate students, 5 graduates. For the students the main reason for the course selection should be scientific vocation and affinity with chemistry and biology; most cited positive parameters were faculty and great structure, practical classes and broad playing field; most cited negatives were high mandatory disciplines, little student free time and lack of sophisticated equipment. Despite the conception of the programs have happened in different contexts and regions we noted similarities deficiencies and distresses. CONCLUSION: Difficulties must be

  19. The Biochemistry Tetrahedron and the Development of the Taxonomy of Biochemistry External Representations (TOBER)

    Towns, Marcy H.; Raker, Jeffrey R.; Becker, Nicole; Harle, Marissa; Sutcliffe, Jonathan


    Visual literacy, the ability to interpret and create external representations (ERs), is essential to success in biochemistry. Studies have been conducted that describe students' abilities to use and interpret specific types of ERs. However, a framework for describing ERs derived through a naturalistic inquiry of biochemistry classrooms has not…

  20. BOREAS TE-9 NSA Canopy Biochemistry

    Hall, Forrest G. (Editor); Curd, Shelaine (Editor); Margolis, Hank; Charest, Martin; Sy, Mikailou


    The BOREAS TE-9 team collected several data sets related to chemical and photosynthetic properties of leaves. This data set contains canopy biochemistry data collected in 1994 in the NSA at the YJP, OJR, OBS, UBS, and OA sites, including biochemistry lignin, nitrogen, cellulose, starch, and fiber concentrations. These data were collected to study the spatial and temporal changes in the canopy biochemistry of boreal forest cover types and how a high-resolution radiative transfer model in the mid-infrared could be applied in an effort to obtain better estimates of canopy biochemical properties using remote sensing. The data are available in tabular ASCII files. The data files are available on a CD-ROM (see document number 20010000884), or from the Oak Ridge National Laboratory (ORNL) Distributed Active Archive Center (DAAC).

  1. Effects of intensive mariculture on sediment biochemistry

    Pusceddu, Antonio; Fraschetti, Simonetta; Mirto, Simone;


    The exponential growth of off-shore mariculture that has occurred worldwide over the last 10 years has raised concern about the impact of the waste produced by this industry on the ecological integrity of the sea bottom. Investigations into this potential source of impact on the biochemistry of the...... sea floor have provided contrasting results, and no compelling explanations for these discrepancies have been provided to date. To quantify the impact of fish-farm activities on the biochemistry of sediments, we have investigated the quantity and biochemical composition of sediment organic matter in...... regions, with the exception of seagrass sediments in Spain, the biochemistry of the sediments showed significant differences between the control and fish-farm locations. However, the variables explaining the differences observed varied among the regions and between habitats, suggesting idiosyncratic...

  2. EDITORIAL: New Editor-in-Chief for Nanotechnology New Editor-in-Chief for Nanotechnology

    Couzin, Nina


    Nanotechnology is proud to announce the appointment of Professor Mark Reed, Yale University, as the new Editor-in-Chief from January 2009. Mark Reed holds the Harold Hodgkinson Chair of Engineering and Applied Science at Yale University. He has made significant contributions in the areas of quantum dots, electronic transport in nanoscale and mesoscopic systems, artificially structured materials and devices, and molecular electronics. Professor Reed has been associated with the journal as an Editorial Board member for a number of years and we are delighted that he has agreed to take on the scientific leadership of the journal in its 20th year. We also take the opportunity to thank Professor Mark Welland, Cambridge University, for his work as Editor-in-Chief since 2001, and for presiding over the re-launch and remarkable growth of the journal since then. Nanotechnology is unique in that it was the first peer-reviewed journal in the area of nanoscience, the first issue appearing in 1990. Since then it has established a distinguished publication record and has become a leading journal covering all aspects of nanoscale science and technology, as well as specializing in in-depth, comprehensive articles not seen in letter format journals. Published weekly and featuring subject sections, the journal is truly multidisciplinary in nature and is an excellent medium to quickly deliver your research results to readers worldwide. Nanotechnology is proud to be offering some of the fastest publication times around (less than three months on average from receipt to online publication). We offer free online access to all published papers for 30 days, ensuring that anyone with access to the internet will be able to read your paper. We were also the first journal to give our authors the opportunity to communicate their research to a wider audience through and other IOP websites. See the journal's homepage at for more details. We are looking

  3. New Expectations Make State Chiefs Hot Commodities

    Richard, Alan


    This article discusses Arkansas' new compensation package for its new education chief. One recent candidate for the state education director's job is said to have had discussions that included a salary of about $240,000, a substantial bonus for staying a certain number of years, and possibly even a professor's chair at a state university upon…

  4. The Chief Clinical Informatics Officer (CCIO)

    Sengstack, Patricia; Thyvalikakath, Thankam Paul; Poikonen, John; Middleton, Blackford; Payne, Thomas; Lehmann, Christoph U


    Summary Introduction The emerging operational role of the “Chief Clinical Informatics Officer” (CCIO) remains heterogeneous with individuals deriving from a variety of clinical settings and backgrounds. The CCIO is defined in title, responsibility, and scope of practice by local organizations. The term encompasses the more commonly used Chief Medical Informatics Officer (CMIO) and Chief Nursing Informatics Officer (CNIO) as well as the rarely used Chief Pharmacy Informatics Officer (CPIO) and Chief Dental Informatics Officer (CDIO). Background The American Medical Informatics Association (AMIA) identified a need to better delineate the knowledge, education, skillsets, and operational scope of the CCIO in an attempt to address the challenges surrounding the professional development and the hiring processes of CCIOs. Discussion An AMIA task force developed knowledge, education, and operational skillset recommendations for CCIOs focusing on the common core aspect and describing individual differences based on Clinical Informatics focus. The task force concluded that while the role of the CCIO currently is diverse, a growing body of Clinical Informatics and increasing certification efforts are resulting in increased homogeneity. The task force advised that 1.) To achieve a predictable and desirable skillset, the CCIO must complete clearly defined and specified Clinical Informatics education and training. 2.) Future education and training must reflect the changing body of knowledge and must be guided by changing day-to-day informatics challenges. Conclusion A better defined and specified education and skillset for all CCIO positions will motivate the CCIO workforce and empower them to perform the job of a 21st century CCIO. Formally educated and trained CCIOs will provide a competitive advantage to their respective enterprise by fully utilizing the power of Informatics science. PMID:27081413

  5. Commentary: PhDs in Biochemistry Education--5 Years Later

    Offerdahl, Erika G.; Momsen, Jennifer L.; Osgood, Marcy


    In this commentary, the discussion of PhDs in biochemistry education research is expanded to explore a number of diverse pathways leading to a competitive research program in biochemistry education research.

  6. Rhetorical Structure of Biochemistry Research Articles

    Kanoksilapatham, Budsaba


    This paper reports on the results of a move analysis [Swales, J. (1990). "Genre analysis." Cambridge: Cambridge University Press] of 60 biochemistry research articles. First, a corpus was systematically compiled to ensure that it represents core journals in the focused discipline. Then, coding reliability analysis was conducted to demonstrate…

  7. Identification of Threshold Concepts for Biochemistry

    Loertscher, Jennifer; Green, David; Lewis, Jennifer E.; Lin, Sara; Minderhout, Vicky


    Threshold concepts (TCs) are concepts that, when mastered, represent a transformed understanding of a discipline without which the learner cannot progress. We have undertaken a process involving more than 75 faculty members and 50 undergraduate students to identify a working list of TCs for biochemistry. The process of identifying TCs for…

  8. Jmol-Enhanced Biochemistry Research Projects

    Saderholm, Matthew; Reynolds, Anthony


    We developed a protein research project for a one-semester biochemistry lecture class to enhance learning and more effectively train students to understand protein structure and function. During this semester-long process, students select a protein with known structure and then research its structure, sequence, and function. This project…

  9. Biochemistry in the idea of graduation students

    D. F. Escoto et al


    Full Text Available INTRODUCTION AND OBJECTIVE: Biochemistry is an interdisciplinary area that allows us to study chemical phenomena in live organisms. That way, its study is of extreme importance, in all levels, to enlarge the comprehension of natural phenomena. However, it is barely explored in the basic education and often fragmented in the higher education, or in graduation degrees that contemplate this area. Especially in the teacher training, where the fragmentation of knowledge can contribute to form wrong concepts. Based on that, this work aims to identify the concept of Biochemistry according to the future teachers of Natural Science. MATERIALS AND METHODS: The work was developed with 3º, 5º and 9º semesters students of the natural science degree on Universidade Federal do Pampa. 50 students, from 18 to 56 years old, were interviewed. The data was obtained through a semi-structured questionnaire. The methodology of categorization and analysis of content with emergent categories of speech was chosen for the analysis. RESULTS AND CONCLUSION: Initially, 11 categories were chosen by content similarity. In descending order: chemical reactions in organisms, chemistry area, chemistry of life, cell metabolism, the study of living beings, origin of life, biology area, organic balance, chemical-biological study. The reports made possible to identify that most students do understand with clarity the goal of studying biochemistry. Although, we can see that there are some students that fragment the area, what means, they try to discriminate chemistry from biology. This way, they demonstrate a difficulty to comprehend biochemistry as interdisciplinary, what makes it hard to contextualize the built knowledge. It is important to develop strategies to overcome the fragmentation of knowledge, so that biochemistry can be comprehended in its fullness and help on the teaching processes that will be developed by the future teachers.

  10. A Biochemistry and Molecular Biology Course for Secondary School Teachers

    Fernandez-Novell, J. M.; Cid, E.; Gomis, R.; Barbera, A.; Guinovart, J. J.


    This article describes a course for reinforcing the knowledge of biochemistry in secondary school science teachers. The Department of Biochemistry and Molecular Biology of the University of Barcelona designed a course to bring these teachers up to date with this discipline. In addition to updating their knowledge of biochemistry and molecular…

  11. Television Medical Dramas as Case Studies in Biochemistry

    Millard, Julie T.


    Several case studies from popular television medical dramas are described for use in an undergraduate biochemistry course. These cases, which illustrate fundamental principles of biochemistry, are used as the basis for problems that can be discussed further in small groups. Medical cases provide an interesting context for biochemistry with video…

  12. 28 CFR 0.117 - Office of Chief Immigration Judge.


    ... accordance with the Immigration and Nationality Act, 8 U.S.C. 1226 and 1252 and 8 CFR 3.9. ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Office of Chief Immigration Judge. 0.117... Executive Office for Immigration Review § 0.117 Office of Chief Immigration Judge. The Chief...

  13. Chief executive pay and remuneration committee independence

    Gregory-Smith, I.


    This article tests the impact of remuneration committee independence on Chief Executive (CEO) pay. FTSE350 companies between 1996 and 2008 are used to assess whether remuneration committees facilitate optimal contracting or whether CEOs capture the pay-setting process and inflate their own remuneration. This panel has a number of advantages over prior samples and, in particular, contains a more comprehensive assessment of non-executive directors' independence. No evidence of a relationship be...

  14. From the Editor-in-chief

    Simeon Oka


    Full Text Available Special issue of the journal Thermal Science dedicated to Dubrovnik Conference on Sustainable Development become already traditional. Present issue, Vol. 14, No. 3, 2010, is the 4th one, and contains selected papers presented at the 5th Dubrovnik Conference on Sustainable Development of Energy, Water, and Environment Systems, held from September 30 to October 3, 2009, in Dubrovnik, Croatia. 5th Dubrovnik Conference was held in the shadow of the new European Energy policy, formulated in short as: "a new energy-climate pack age of measures, reaching for obligatory targets of 20% renewable energy in gross consumption, 10% renewable fuels in transport, 20% decrease of greenhouse gases emissions, and 20% in crease of energy efficiency by 2020". Considering this fact, selection of the papers for this issue has the aim to show the reflection of this process on the energy policy and practice in the countries of the South East European region (SEE region. Selection of papers presented at the 5th Dubrovnik Conference, done by Guest editors, clearly shows that countries of the SEE region, depending on specific energy and economic conditions, made great efforts to follow recommendations of the new European energy policy, and to meet challenges of climate changes, and at the same time to in crease security of energy supply. I am deeply grateful to the Guest editors, Professors Neven Duić, Zvonimir Guzović, and Daniel R. Schneider, for excellent paper selection, the job which is at the same time highly professional and delicate. I am sure, that readers will obtain realistic insight in the policies, activities, achievements, results, and barriers, existing in most of the countries in the South East European region, along their movement towards sustainable development. Having in mind in creased interest in research and engineering activities aimed to "improvement and dissemination of knowledge on methods, policies, and technologies for increasing the

  15. Pracital examination in biochemistry: topics and procedures?

    Vocke, Nils-Daniel


    Full Text Available Under the new revision of the German licensing regulations for physicians ("Approbationsordnung" the rules for the first national examinations (i.e. "Physikum", equivalent to medical school entrance exams have been changed. In addition to the written exam a novel "oral-practical" part is required. Here we describe the implications of this oral-practical exam on the examination procedures in the field of biochemistry/molecular biology. A strategy for its realization is proposed.


    C. E.S. Rocha; M. D. Büttenbender; R. Roehrs


    INTRODUCTION: Being present in high school in chemistry and biology disciplines, biochemistry is to explain the chemical and biological reactions in cells. His concepts are seen as abstract and difficult to understand and can be contextualized through experimentation. Experimentation is used in the classroom to allow students to view the applicability of the contents through observation, creating hypotheses, discussion and conclusions. OBJECTIVES: The aim of this study was to evaluate the pre...

  17. Concept mapping enhances learning of biochemistry

    Surapaneni, Krishna M.; Tekian, Ara


    Background: Teaching basic science courses is challenging in undergraduate medical education because of the ubiquitous use of didactic lectures and reward for recall of factual information during examinations. The purpose of this study is to introduce concept maps with clinical cases (the innovative program) to improve learning of biochemistry course content. Methods: Participants were first year medical students (n=150) from Saveetha Medical College and Hospital (India); they were randomly d...

  18. $^{31}$Mg $\\beta$-NMR applied in chemistry and biochemistry

    Magnesium ions, Mg$^{2+}$, are essential in biological systems, taking part in practically all phosphate chemistry, in photosynthesis as an integral component of chlorophyll, and they are regulated via transport through selective membrane proteins. Nonetheless, the function of magnesium ions in biochemistry is difficult to characterize, as it is practically invisible to current experimental techniques. With this proposal we aim to advance the use of $^{31}$Mg $\\beta$-NMR to liquid samples, building on the experience from the successful LOI88 “$\\beta$-NMR as a novel technique for biological applications”. Initially a series of experiments will be conducted aiming to characterize the coordination chemistry of Mg$^{2+}$ in ionic liquids (ILs), demonstrating that it is possible within the lifetime of the radioisotope to achieve binding of Mg$^{2+}$ to a molecule dissolved in the IL. ILs are chosen as they display a very low vapor pressure, and are thus straightforwardly compatible with the vacuum requirements...

  19. A Project-Oriented Biochemistry Laboratory Course

    Craig, Paul A.


    A project-oriented laboratory course has been designed to introduce students to the study of biochemistry as it is practiced. The course is designed to be a capstone experience for students enrolled in a variety of majors at the Rochester Institute of Technology, including those who enter our new B.S. Biochemistry program. The experiments in this course enable the students to explore the protein chemistry, enzymology, and molecular biology of a single enzyme, threonine dehydrogenase, in a series of integrated experiments. The laboratory incorporates both traditional methods (centrifugation, UV-vis spectroscopy, gel electrophoresis, and chromatography) and more recent developments in the field (polymerase chain reaction). Students use a small computer network to prepare for experiments (using simulation software developed at RIT), to evaluate data, to access sequence homology databases over the Internet, and to visualize and model proteins and nucleic acids. The change in the biochemistry teaching lab from a sequence of unrelated experiments to an integrated series of experiments is a model that can be readily adapted by other educators, who can change their courses to focus on a single enzyme with which they are most familiar.

  20. Concept mapping enhances learning of biochemistry

    Krishna M. Surapaneni


    Full Text Available Background: Teaching basic science courses is challenging in undergraduate medical education because of the ubiquitous use of didactic lectures and reward for recall of factual information during examinations. The purpose of this study is to introduce concept maps with clinical cases (the innovative program to improve learning of biochemistry course content. Methods: Participants were first year medical students (n=150 from Saveetha Medical College and Hospital (India; they were randomly divided into two groups of 75, one group attending the traditional program, the other the innovative program. Student performance was measured using three written knowledge tests (each with a maximum score of 20. The students also evaluated the relevance of the learning process using a 12-item questionnaire. Results: Students in the innovative program using concept mapping outperformed those in the traditional didactic program (means of 7.13–8.28 vs. 12.33–13.93, p<0.001. The students gave high positive ratings for the innovative course (93–100% agreement. Conclusion: The new concept-mapping program resulted in higher academic performance compared to the traditional course and was perceived favorably by the students. They especially valued the use of concept mapping as learning tools to foster the relevance of biochemistry to clinical practice, and to enhance their reasoning and learning skills, as well as their deeper understanding for biochemistry.


    G. B. Lazzarotto


    Full Text Available This work presents a game like educational software (courseware to study metabolic pathways, calledDiagrama Metabolico Din^amico Virtual (DMDV of Krebs Cycle. The experience acquired teachingwith the logical sequence tray games in the FFFCMPAs Biochemistry Course provides the beddingswith the use of this model as education method. With DMDV, students can assembly the sequenceof reactions that describe the desired metabolic pathway, create situational models which can guidehis/her choices, reduce the subject complexity of the scheme in knowledge construction presentingin a graphical way the current interrelations. Biochemistry teachers can use the present software inclassroom as well as distance classes. This product integrates multimedia resources extensively andis distributed in CD-ROM format. The virtual environment will make possible interaction of thestudent with the environment and with colleagues and teachers, through tools as chats and forum.Experience with the use of this method was carried through with two distinct groups of students.The rst group was composed by 11 students, who were more familiar with the content and answereda specic questionnaire to previously evaluate the software. The second group was formed by 24students regularly registered in the FFFCMPAs Biochemistry Course, who used the software as astudy method. The rst group considered DMDV of easy and pleasant navigation. The knowledgeevaluation of the second group students was made by a written test and the analysis of three conceptualmaps constructed by each one of them: one map before initiating the study with the DMDV, thesecond just after the study and the third one two months later. Every conceptual maps producedafter DMDV method showed an expansion of valid concepts if compared with the rst maps. Simplevisual comparison of maps shows that new elements where added. All students who passed throughthe experiment reached a greater than ve grade in the subjects written


    C. E.S. Rocha


    Full Text Available INTRODUCTION: Being present in high school in chemistry and biology disciplines, biochemistry is to explain the chemical and biological reactions in cells. His concepts are seen as abstract and difficult to understand and can be contextualized through experimentation. Experimentation is used in the classroom to allow students to view the applicability of the contents through observation, creating hypotheses, discussion and conclusions. OBJECTIVES: The aim of this study was to evaluate the presence of experimentation in biochemistry content  in high school books. MATERIALS AND METHODS: In this way, it was analyzed the presence of experimental activities in the textbooks approved by the National Textbook Plan 2015 "Biology 1", authored by César da Silva Junior, Sezar Sasson and Nelson Caldini Junior, and in the book " Chemistry - Volume 3 "by Martha Reis. RESULTS: At the end of the unit where the biochemical concepts are covered in the book "Biology 1" is presented an interdisciplinary project called "Enzymes - chemical tools of life" that proposes four experiments on catalase, pH and contact surface enzyme-substrate. They are easy activities to be implemented with affordable materials. Already at the Chemistry book, when addressing the biochemistry there is only one proposal for experimental activity called "Glycolic Extract of milk proteins". In this case, we need materials like food processor and enameled pots, which can hinder your performance in virtual classes, however, the experiment is easy to perform. Both books contain questions after the experimental proposals enhancing the questioning of the activities and understanding the contents addressed. CONCLUSIONS: The present experimental activities in the textbooks are mostly easy to apply and is not required sophisticated equipment of Sciences laboratories. It also allows the contextualization of theory and practice enhancing the process of teaching and learning with the proposals made.

  3. Guidelines for the Design of Biochemistry Websites

    R.M. Lima


    Full Text Available The internet is a means of communication that cannot be disregarded by contemporaryeducational systems. Public and private incentive policies aimed at the application ofdigital devices in the exchange of knowledge in and outside schools have beenimplemented in the last decades. However, risks posed by academic research on line arewidely acknowledged with regard to the quality of information (Lourenço, 2010. One of themain aspects of this issue is the selection of reliable and potentially educational pagesdeveloped for specific target audiences. This study has the objective of providingguidelines for those who intend to develop sites, wiki pages, and educational PBwikisfocused on Biochemistry, or even adapt existing ones. Considering the fact that there is nospecific legislation for the use of the Internet in Brazil, it is necessary to stimulate selfregulationof the sector in order to establish minimum quality standards, safety, andreliability of sites containing information in the educational area. Thus, it is necessary toestablish some parameters to help guiding research for educational purposes on theinternet. To be a potentially didactic Biochemistry page, one must follow this set oforientation: clearly establish the target audience and, then, define the contents the properway. Once the materials have been organized, establish, whenever possible and pertinent,links with references to professional and/ or research home pages, to ProfessionalAssociations in the Biochemistry field, among others. Link the page to an institutionalresearch program, such as International Virtual Education Network, a program developedby the Brazilian Distance Education Department. Finally, it is necessary to provideinteractive possibilities and dynamic images of the biochemical processes studied in classthat will justify and differentiate the page from the many existing ones. Such proceduresare essential to guarantee that online searches made for educational

  4. Chief officer misconduct in policing: an exploratory study

    Hales, Gavin; May, Tiggey; Belur, J.; Hough, Mike


    Key findings This study has examined cases of alleged misconduct involving chief police officers and staff. The aim was to describe the nature of cases that have come to light, examine the perceived pathways that led to misconduct, and suggest ways of mitigating the risks of misconduct. The study is based on interviews with key stakeholders and with investigating officers in chief officer misconduct cases since April 2008. These cases involved only a small minority of chief ...

  5. Penta-coordinate phosphorous compounds and biochemistry

    林长学; 韩波; 赵玉芬; 万荣; 李艳梅; 冯亚兵; 成昌梅


    The relationship between penta-coordinate phosphorus compounds and biochemistry is briefly reviewed. Some interesting phenomena such as peptide formation, ester formation, ester exchange on phosphorus and N to O migration occur at room temperature when the amino group of amino acid is associated with phosphoryl group. Serine or threonine in conjugate of nucleo-side-amino acid could recognize different nucleobases. N-phosphoryl Histine and Ser-His dipep-tide could cleavage nucleic acid, protein and ester in neutral medium. It is found that the above phenomena all undergo penta-coordinate intermediate of phosphorus atom, which is proposed as the key factor to determine their activities.

  6. Radioactive isotopes in biochemistry (historical essay)

    A large volume of facts, including little-known biobibliographic data on the the first reserchers who applied the method, are used in the study. The main attention is paid to the use of the method of labelled atoms, when considering intermediate exchange of substances and creating metabolic ways maps (the end of 30-ies - beginning of 50-ies). Using as an example the history of creation of the labelled atom method and its introduction into biochemistry, the problem of the research methods transfer from one branch of science to another is considered


    Burlakov M. M.; Rodionova L. Y.; Troshin L. P.; Chausov V. M.


    The article contains results of the study of biochemistry of some perspective table grape varieties: Aniuta, Vodograi, Nizina and Jubilee Novocherkasska, yield in 2013 from the Central zone of Krasnodar region. At the time of redy yield the combination of sweetness and acidity of fruits were favorable. The ratio of fructose to glucose was 1.69; 1.36; 2.00; 1.13, respectively, in grapes Aniuta, Vodograi, Nisina, Jubilee Novocherkasska. According to the percentage of fructose in fruit juice var...

  8. Writing throughout the Biochemistry Curriculum: Synergistic Inquiry-Based Writing Projects for Biochemistry Students

    Mertz, Pamela; Streu, Craig


    This article describes a synergistic two-semester writing sequence for biochemistry courses. In the first semester, students select a putative protein and are tasked with researching their protein largely through bioinformatics resources. In the second semester, students develop original ideas and present them in the form of a research grant…

  9. A Changing Research and Publication Landscape for Biochemistry

    Gabor Mocz


    Full Text Available This introductory editorial hopes to convey three points to its audience. First, it provides an overview of the new, peer-reviewed, open access journal Biochemistry Insights published by Libertas Academica. Second, it summarizes the benefits of open access publishing concepts to the biochemistry community. And third, it takes a brief look at the near future of biochemistry as a fundamental molecular science whose continued advances and latest developments will be the focus of the new journal. Biochemistry Insights looks forward to receiving research articles, review papers, commentaries and letters from all disciplines and specialties of the field.

  10. Chief Inspector's guidance to inspectors: combustion processes

    This Note is issued by the Chief Inspector of Her Majesty's Inspectorate of Pollution (HMIP) as one of a series providing guidance for processes prescribed for integrated pollution control in Regulations made under Section 2 of the United Kingdom Environmental Protection Act 1990. It covers the burning of solid fuel manufactured from or comprised of tyres, tyre rubber or similar rubber waste primarily for the purpose of producing energy, in an appliance with a net rated thermal input of 3 megawatts or more. The note includes: a list of prescribed substances most likely to be present in releases to the environment by the processes considered; release limits for release to air, water and land; an outline of techniques for pollution abatement; monitoring requirements. (Author)

  11. Contributions of nuclear magnetic resonance to renal biochemistry

    31P NMR as a descriptive technique is of interest to nephrologists. Particular contributions of 31P NMR to our understanding of renal function may be enumerated.: Free metabolite levels are different from those classically accepted; in particular, ADP and Pi are low with implications for the control of renal metabolism and Pi transport, and, via the phosphorylation potential, for Na+ transport. Renal pH is heterogeneous; between cortex, outer medulla, and papilla, and between cell and lumen, a large pH gradient exists. Also, quantitation between cytosol and mitochondrion of the pH gradient is now feasible. In acute renal failure of either ischemic or nonischemic origin, both ATP depletion and acidification of the renal cell result in damage, with increasing evidence for the importance of the latter. Measurements of renal metabolic rate in vivo suggest the existence of a prodromal phase of acute renal failure, which could lead to its detection at an earlier and possibly reversible stage. Human renal cancers show a unique 31P NMR spectrum and a very acidic environment. Cancer chemotherapy may alter this and detection of such changes with NMR offers a method of therapeutic monitoring with significance beyond nephrology. Renal cortex and medulla have a different T1 relaxation time, possibly due to differences in lipid composition. It seems that NMR spectroscopy has much to offer to the future understanding of the relationship between renal biochemistry and function. 56 references

  12. EDITORIAL: Incoming Editor-in-Chief

    Webb, Steve


    editor signals change and in turn this induces in some people expectation, hope of improvement and maybe radical revolution. Others cower and hope for stability, continuation of the same and as little outward sign of change as possible. So I should like to signal that I hope to satisfy both camps. The Editor-in-Chief is primarily a guardian of the journal and should change nothing that does not need changing. Maintaining a standard at the same level is a valuable achievement in itself. This is no different from taking on any other leadership role such as in a team or department. One has to lead by consensus and with respect for the position. Conversely there are things I would like to see improved (otherwise I should not have been hired) and I commit to attempting these but in a spirit of cooperation with the Board, the publisher (IOP), IPEM and the readership. Any other approach would be doomed anyway. So, what would I like to see changed? Dare I say anything too strongly upfront? Like Alun six years ago I would like there to be more debate via correspondence but this depends on the readers to do more writing along these lines. Personally I feel PMB, like many journals, has developed to the point where most readers sadly can understand only a small fraction of its contents. I have talked to older readers who said they regularly used to read all or half of the journal. Now many of us can manage only the papers in our specialty. Yet this is somewhat inevitable as medical physics has progressed from a fledgling science to the vast activity it is today, topics have become deeply complicated and we cannot and should not reverse the clock. To address this, I would like to see authors provide some form of `intelligible lay-scientific summary' of their paper as a condition of its publication. I think readers would then enjoy reading all, not just some, of these and maybe become attracted to other areas than the ones in which they currently work. I would like to see the

  13. A National Comparison of Biochemistry and Molecular Biology Capstone Experiences

    Aguanno, Ann; Mertz, Pamela; Martin, Debra; Bell, Ellis


    Recognizing the increasingly integrative nature of the molecular life sciences, the "American Society for Biochemistry and Molecular Biology" (ASBMB) recommends that Biochemistry and Molecular Biology (BMB) programs develop curricula based on concepts, content, topics, and expected student outcomes, rather than courses. To that end,…

  14. A Streamlined Molecular Biology Module for Undergraduate Biochemistry Labs

    Muth, Gregory W.; Chihade, Joseph W.


    Site-directed mutagenesis and other molecular biology techniques, including plasmid manipulation and restriction analysis, are commonly used tools in the biochemistry research laboratory. In redesigning our biochemistry lab curricula, we sought to integrate these techniques into a term-long, project-based course. In the module presented here,…

  15. Immobilized alpha-Galactosidase in the Biochemistry Laboratory

    Mulimani, V. H.; Dhananjay, K.


    This laboratory experiment was designed to demonstrate the application of immobilized galactosidase in food industry to hydrolyze raffinose family oligosaccharides in soymilk. This laboratory experiment was conducted for postgraduate students of biochemistry and developed for graduate and undergraduate students of biochemistry, biotechnology,…

  16. News from Online: WWW Sites for Biochemistry Teachers

    Hicks, Barry W.


    With so many biochemistry sites to choose from, searching the Web for biochemistry topics is like being a "kid in a candy shop." However, to reap the benefits, you must put in a bit of time and have a bit of patience. Good hunting.

  17. Using Pamphlets to Teach Biochemistry: A Service-Learning Project

    Harrison, Melinda A.; Dunbar, David; Lopatto, David


    A service-learning project appropriate for a biochemistry or advanced biochemistry course was designed and implemented. The project involved students partnering with a homeless shelter to design informational pamphlets to be displayed at the shelter for the clients' use. The pamphlet topics were based on diseases studied within the course.…

  18. Commentary: Biochemistry and Molecular Biology Educators Launch National Network

    Bailey, Cheryl; Bell, Ellis; Johnson, Margaret; Mattos, Carla; Sears, Duane; White, Harold B.


    The American Society of Biochemistry and Molecular Biology (ASBMB) has launched an National Science Foundation (NSF)-funded 5 year project to support biochemistry and molecular biology educators learning what and how students learn. As a part of this initiative, hundreds of life scientists will plan and develop a rich central resource for…

  19. Blended Learning in Biochemistry Education: Analysis of Medical Students' Perceptions

    Wardenski, Rosilaine de Fatima; de Espindola, Marina Bazzo; Struchiner, Miriam; Giannella, Tais Rabetti


    The objective of this study was to analyze first-year UFRJ medical students' perceptions about the implementation of a blended learning (BL) experience in their Biochemistry I course. During the first semester of 2009, three Biochemistry professors used the Constructore course management system to develop virtual learning environments (VLEs) for…

  20. Enhanced Podcasts for Teaching Biochemistry to Veterinary Students

    Gough, Kevin C.


    The teaching of biochemistry within medical disciplines presents certain challenges; firstly to relay a large body of complex facts and abstract concepts, and secondly to motivate students that this relatively difficult topic is worth their time to study. Here, nutrient biochemistry was taught within a multidisciplinary module as part of an…

  1. The Teaching of Biochemistry: An Innovative Course Sequence Based on the Logic of Chemistry

    Jakubowski, Henry V.; Owen, Whyte G.


    An innovative course sequence for the teaching of biochemistry is offered, which more truly reflects the common philosophy found in biochemistry texts: that the foundation of biological phenomena can best be understood through the logic of chemistry. Topic order is chosen to develop an emerging understanding that is based on chemical principles. Preeminent biological questions serve as a framework for the course. Lipid and lipid-aggregate structures are introduced first, since it is more logical to discuss the intermolecular association of simple amphiphiles to form micelle and bilayer formations than to discuss the complexities of protein structure/folding. Protein, nucleic acid, and carbohydrate structures are studied next. Binding, a noncovalent process and the simplest expression of macromolecular function, follows. The physical (noncovalent) transport of solute molecules across a biological membrane is studied next, followed by the chemical transformation of substrates by enzymes. These are logical extensions of the expression of molecular function, first involving a simpler (physical transport) and second, a more complex (covalent transformation) process. The final sequence involves energy and signal transduction. This unique course sequence emerges naturally when chemical logic is used as an organizing paradigm for structuring a biochemistry course. Traditional order, which seems to reflect historic trends in research, or even an order derived from the central dogma of biology can not provide this logical framework.

  2. Bone Biochemistry on the International Space Station

    Smith, Scott M.; Heer, Martina; Zwart, Sara R.


    Bone biochemical measures provide valuable insight into the nature and time course of microgravity effects on bone during space flight, where imaging technology cannot be employed. Increased bone resorption is a hallmark of space flight, while markers of bone formation are typically unchanged or decreased. Recent studies (after the deployment to ISS of the advanced resistive exercise device, ARED), have documented that astronauts with good nutritional intake (e.g., maintenance of body mass), good vitamin D status, and exercise maintained bone mineral density. These data are encouraging, but crewmembers exercising on the ARED do have alterations in bone biochemistry, specifically, bone resorption is still increased above preflight levels, but bone formation is also significantly increased. While this bone remodeling raises questions about the strength of the resulting bone, however documents beneficial effects of nutrition and exercise in counteracting bone loss of space flight.

  3. Biochemistry Teaching Through Food Label Analysis

    N.L. Barbosa; Y.M. Correia; Nascimento, M. M.; H.D. Oliveira


    Traditional classes of Basic Biochemistry often rely on memorization of facts and concepts.  For  this  reason,  many  educators  have  evaluated  new  strategies  and tools  to  enrich  learning  and  motivate  undergraduate  students.  As  a  result  of different  methodologies  used  for  this  purpose,  several  commited  professors  are convinced  that  students  learn  more  effectively  if  the  knowledge  they  acquire  are inserted and contextualized in relevant real-life. This work ...

  4. Immobilized Lactase in the Biochemistry Laboratory

    Allison, Matthew J.; Bering, C. Larry


    Immobilized enzymes have many practical applications. They may be used in clinical, industrial, and biotechnological laboratories and in many clinical diagnostic kits. For educational purposes, use of immobilized enzymes can easily be taught at the undergraduate or even secondary level. We have developed an immobilized enzyme experiment that combines many practical techniques used in the biochemistry laboratory and fits within a three-hour time frame. In this experiment, lactase from over-the-counter tablets for patients with lactose intolerance is immobilized in polyacrylamide, which is then milled into small beads and placed into a chromatography column. A lactose solution is added to the column and the eluant is assayed using the glucose oxidase assay, available as a kit. We have determined the optimal conditions to give the greatest turnover of lactose while allowing the immobilized enzymes to be active for long periods at room temperature.

  5. Evaluation of Educational Media Covering Biochemistry Concepts

    Lima C.A.


    Full Text Available INTRODUCTION: With the increase of Information and Communications Technologies, ithas developed many tools which can be used in the biochemistry teaching, such aswebsites, films, educational software, that enable the visualization of microscopic andsubmicroscopic processes which has a difficult understanding. The use of software can bean integrating part of the teaching learning process, in order to assist or to contribute for abetter construction of knowledge. OBJECTIVES: Identify the educational media availablefor teaching biochemistry and to evaluate, qualitatively, these tools. MATERIAL ANDMETHODS: The educational media were selected through searchers on the web and theywere evaluated by four evaluators, using a specific questionnaire. The form was madeusing quality parameters in the following areas: media technical quality; educationalaspects; content and use; and the use in virtual environments. A scale from 1 to 5, NA (notapplicable were used and yes or no for the binary questions. After, was made theaverages and standard deviations by category and media. RESULTS ANDDISCUSSIONS: Were selected and evaluated 40 educational medias, highlighting thefollowing results in the media technical quality: ease of access, ease of installation andreliability, however, need to improve the interactivity of these media, as well asaccessibility. On the educational aspects issue the highlights are for updated informationand the way they enable the construction of knowledge. When referring to the contentassessed, the item that stood out was the exemption of textual errors. The lowest valuesof the evaluation, overall, gave up the use in virtual environments, indicating the demandfor better integration with these environments. CONCLUSION: Applications reviewsexpressed concern in its construction, with respect to general aspects of quality, however,still demand a greater concern about the interaction with the student, and betteraccessibility and incorporation

  6. Dyslipidemias as generating issue in Biochemistry classes

    R. M. Lima


    Full Text Available The traditional didactic model is based on the transmission of the teacher's encyclopedic knowledge. In this model, the teaching of Science aims at the transmission of dominant values, regarded as absolute truths. The teacher is seen is an expert on scientific contents who transmits them to students without motivating them, and without taking into consideration their previous ideas and life experience. This model contributes to the formation of professionals who accept those values uncritically. An effective approach to break up this traditional teaching model in Biochemistry is the use of a generating issue. A Generating Issue is the starting point to the knowledge construction process which, in turn, replaces traditional models. Thus, this study aimed at developing a lesson for a 12th grade class at IF Fluminense on the following content: alcohol, carboxylic acid, ester, and esterification reaction, using dyslipidemias as the Generating Issue. To verify the value of such methodology in Biochemistry classroom, data was collected by applying a questionnaire and images with texts produced by students. In addition, they had a class based on the methodology known as Three Pedagogical Moments, proposed by Delizoicov et al. (2007. Several didactic resources designed by the authors were used, such as slide presentation, tridimensional molecular models, and a roulette game named “Bioquimicados”, based on the Facebook game “Perguntados” ("Trivia Crack". After this, students developed more grounded scientific concepts, making use of terms common in scientific language. This suggests that the use of the Generating Issue in a lesson based on problematization, and supported by a ludic activity, provided a meaningful contribution to improve the students' understanding of the scientific content. This type of non-traditional class promotes greater student motivation, resulting in meaningful learning.

  7. Audit of the Federal Energy Regulatory Commission`s Office of Chief Accountant



    The Federal Energy Regulatory Commission`s (Commission) mission is to oversee America`s natural gas and oil pipeline transportation, electric utility, and hydroelectric power industries to ensure that consumers receive adequate energy supplies at just and reasonable rates. To carry out this mission, the Commission issues regulations covering the accounting, reporting, and rate-making requirements of the regulated utility companies. The Commission`s Office of Chief Accountant performs financial related audits at companies to ensure compliance with these regulations. The purpose of this audit was to evaluate the office of Chief Accountant`s audit performance. Specifically, the objectives were to determine if the most appropriate audit approach was used and if a quality assurance process was in place to ensure reports were accurate and supported by the working papers.

  8. The chief data officer handbook for data governance

    Soares, Sunil


    A practical guide for today's chief data officers to define and manage data governance programs   The relatively new role of chief data officer (CDO) has been created to address the issue of managing a company's data as a strategic asset, but the problem is that there is no universally accepted "playbook" for this role. Magnifying the challenge is the rapidly increasing volume and complexity of data, as well as regulatory compliance as it relates to data. In this book, Sunil Soares provides a practical guide for today's chief data officers to manage data as an asset while delivering the truste

  9. The semiosis of students’ conceptual understanding of biochemistry

    Musaeus, Peter; Mathiesen, Søren Læssøe; Dahl, Mads Ronald


    university teaching including biochemistry teaching (Loertscher, 2011). The study seeks an answer to the problem of emergence in science students acquisition of concepts, not only how students form new sign hierarchies over time, but how say easy concepts suddenly change into a hard concepts(or vice versa...... analogue scales) of biochemical concepts were collected every week during a university semester. Archival data (e.g. biochemistry textbooks), diaries and a qualitative interview were collected with a biochemistry teacher. Methodological challenges are identified in studying conceptual change and the...

  10. Online Communication Tools in Biochemistry Teaching

    A. O. Ferreira


    Full Text Available The  online  communication  tools  enable  new  ways  of  learning, especially  the  forums  in the context of online courses, and the understanding of interactions and collaborations in the  forums  can  improve  them.  The  study  aimed  to  analyze  the  online relationships,  as well  as  obtaining  evidence  of  the  use of  other  learning  tools in  a  biochemistry  subject, focusing on how students use the tool forum and its contribution to learning. The study was  carried  out  from  data  pre  and  post  course  questionnaires  as  well  as  log  of environment  access  and  discussion  forum.  The  forums  have  been  restructured  and systematized  for  analysis  and  creating  discursive  flows  between  statements.  The questionnaires showed the central role of forum and wiki for learning,  the importance of interactions, which was highlighted by the forum analysis. The results indicate that one of the ways to improve online biochemistry teaching is to stimulate interactive activities, participatory  moderation  and  pedagogical  support  by  tutors  and  mentors,  also encouraging  and  creating  strategies  to  collaboration  of  students  to  solve problems  and to collaborative knowledge construction.

  11. WVTF chief engineer receives award from Virginia Association of Broadcasters

    Virginia Tech News


    WVTF Chief Engineer Paxton Durham has received the J. Jerry Freeman Engineering Achievement Award from the Virginia Association of Broadcasters. He accepted the award at the association's June 25 annual meeting.

  12. Office of the Chief Financial Officer Annual Report 2009

    Fernandez, Jeffrey


    Presented is the 2009 Chief Financial Officer's Annual Report. The data included in this report has been compiled from the Budget Office, the Controller, Procurement and Property Management and the Sponsored Projects Office.

  13. Office of Chief Scientist, Integrated Research Facility (OCSIRF)

    Federal Laboratory Consortium — Introduction The Integrated Research Facility (IRF) is part of the Office of the Chief Scientist (OCS) for the Division of Clinical Research in the NIAID Office of...

  14. Hobby with Biochemistry: Use of active learning methodology in Biochemistry at the Medical School

    S. R.T. Prado


    Full Text Available Introduction and objectives: The learning of Biochemistry is generally considered difficult by the graduates, because studies the molecular level the metabolism of living and it demands a great capacity for abstraction by students. Thus, researchers have tried alternative methods to provid an alternative study method. Materials and methods: 178 students of the School of Medicine, PUC-PR, that course the disciplines of Medical Biochemistry I and II, were divided into 50 groups, each with 3-4 students, and were have to draw up a hobby activity with a specific theme of the Biochemistry. The selected topics were, amino acids and proteins, enzymes, cellular respiration, glycogen metabolism, gluconeogenesis, lipid metabolism, metabolic integration, dyslipidemia and atherogenesis, pathophysiology of diabetes mellitus and metabolic syndrome, mechanisms of diabetes mellitus complications. The hobby activities chosen were direct, duplex, self-defined, cryptogram, bugs game. Both issues such as the type of hobby was drawn between groups. The groups had to: elaborate hobby; presents it to class orally, applying the questions prepared; printing and expose the hobby at the wall in the University; answer an evaluation regarding the preparation of work; and all groups should get together and organize one titled magazine "Hobby with Biochemistry" and deliver it printed. Results and conclusions: According the groups, the greatest difficulty was the adequacy of the questions posed in the required format, once they had only one issue and restricted space for the responses. Furthermore, the formatting was also identified as a point very difficult in activity elaboration. On the topic of learning through the development of work, and/or a new skill groups assigned grades ranging between 7.0 and 10.0 and about 90% of the groups attributed note 10 on satisfaction of seeing the work done and its ability to produce it. According to the results, the activity proved to be

  15. International Environmental Law and Biochemistry: An Innovative Teaching Opportunity.

    Candlish, John


    Explores the ties between international environmental law and biochemistry with respect to genetically modified organisms, biodiversity, marine pollution, cancer biology, and pesticide contamination of food. Contains 30 references. (DDR)

  16. Teaching human genetics in biochemistry by computer literature searching.

    Proud, V. K.; Schmidt, F J; Johnson, E D; Mitchell, J. A.


    We describe a new user-intense-learning experience that incorporates the teaching of clinical and research applications of human genetics in biochemistry while training first-year medical students to develop skills in computer access to the literature. Human genetics was incorporated into the biochemistry curriculum by providing each student with experience in on-line literature searching in MEDLINE, using Grateful Med, in order to write an abstract about a specific inherited biochemical diso...

  17. A biochemistry discipline designed for the nutrition course

    A.A.G. Bianco


    Full Text Available Biochemistry is widely considered an essential background in a Nutrition Course framework. At theFaculdade de Saude Publica, USP, it is a direct requirement to eight disciplines of the syllabus and anindirect requirement to another nine disciplines. Nevertheless, a previous interview study involvingNutrition students and Nutritionists revealed a contradictory image of Biochemistry. Although stu-dents and Nutritionists admitted the important role played by Biochemistry, most of the respondentsdeclared that they could not foresee any application of Biochemical contents in their professional life.Aiming to change this situation, a deep intervention in the Biochemistry discipline was carried on.The discipline was planned in such a way that all the contents to be taught was directly derived fromsubjects or situations matching the interests of nutrition students. Instead of a classical lecture basedcourse, collaborative learning was the methodological choice, taking advantage of practical activitiesinvolving educational software and laboratory work as well. The course was carried on in 180 hoursand a variety of strategies were employed, especially small group discussion and problem solving. Thestudents were given a booklet containing all the exercises and problems, which acted as course guide.At the end of the course, an evaluation survey was carried out. It is noticeable that, according tostudents answers: 100% agreed that Biochemistry was intimately linked to Nutrition; 83% appreciatedthe didactical methodologies employed; 89% would like to continue studying Biochemistry in a furtherdiscipline; 96% declared that the discipline has raised their interest in Biochemistry. In respect tothe assessment of the students, these results are in accordance with the opinion of teachers and TAsengaged in restructuring Biochemistry courses.

  18. Geobiochemistry: Placing Biochemistry in Its Geochemical Context

    Shock, E.; Boyer, G. M.; Canovas, P. A., III; Prasad, A.; Dick, J. M.


    Goals of geobiochemistry include simultaneously evaluating the relative stabilities of microbial cells and minerals, and predicting how the composition of biomolecules can change in response to the progress of geochemical reactions. Recent developments in theoretical geochemistry make it possible to predict standard thermodynamic properties of proteins, nucleotides, lipids, and many metabolites including the constituents of the citric acid cycle, at all temperatures and pressures where life is known to occur, and beyond. Combining these predictions with constraints from geochemical data makes it possible to assess the relative stabilities of biomolecules. Resulting independent predictions of the environmental occurrence of homologous proteins and lipid side-chains can be compared with observations from metagenomic and metalipidomic data to quantify geochemical driving forces that shape the composition of biomolecules. In addition, the energetic costs of generating biomolecules from within a diverse range of habitable environments can be evaluated in terms of prevailing geochemical variables. Comparisons of geochemical bioenergetic calculations across habitats leads to the generalization that the availability of H2 determines the cost of autotrophic biosynthesis relative to the aquatic environment external to microbial cells, and that pH, temperature, pressure, and availability of C, N, P, and S are typically secondary. Increasingly reduced conditions, which are determined by reactions of water with mineral surfaces and mineral assemblages, allow many biosynthetic reactions to shift from costing energy to releasing energy. Protein and lipid synthesis, as well as the reverse citric acid cycle, become energy-releasing processes under these conditions. The resulting energy balances that determine habitability contrast dramatically with assumptions derived from oxic surface conditions, such as those where human biochemistry operates.

  19. Recent advances in the biochemistry of spinosyns.

    Huang, Ke-xue; Xia, Liqiu; Zhang, Youming; Ding, Xuezhi; Zahn, James A


    Spinosyn and its analogs, produced by Saccharopolyspora spinosa, are the active ingredients in a family of insect control agents. They are macrolides with a 21-carbon, 12-membered tetracyclic lactones that are attached to two deoxysugars, tri-O-methylrhamnose and forosamine. Labeling studies, analysis of the biosynthetically blocked mutants, and the genetic identification of the spinosyn gene cluster have provided detailed information concerning the mechanism of spinosyn biosynthesis and have enabled combinatorial biosynthesis of a large group of new spinosyns. The following developments have recently impacted the field of spinosyn biology: (1) A second-generation spinosyn called spinetoram (XDE-175) was launched in late 2007; it is a semisynthesized spinosyn derivative produced through the modification of 3'-O-methyl group of rhamnose and the double bond between C5 and C6 of spinosyn J and L. This molecule was shown to have improved insecticidal activity, enhanced duration of control, and an expanded pest spectrum. (2) A new class of spinosyns, the butenyl-spinosyns, was discovered from Saccharopolyspora pogona. The butenyl-spinosyns are similar to spinosyns, but differ in the length of the side chain at C-21. In addition to structural similarities with the spinosyns, the butenyl-spinosyns exhibit a high level of similarity in insecticidal activity to spinetoram. (3) Spinosyn analogs, 21-cyclobutyl-spinosyn A and 21-cyclobutyl-spinosyn D were generated by metabolic engineering of the spinosyn biosynthetic gene cluster. They showed better insecticidal activities against cotton aphid and tobacco budworm than that of spinosyn A and D. Future progress toward the development of more potent spinosad analogs, as well as enhancements in production yields will likely result from these recent advances in the genetics and biochemistry of spinosyns. PMID:19082588


    Burlakov M. M.


    Full Text Available The article contains results of the study of biochemistry of some perspective table grape varieties: Aniuta, Vodograi, Nizina and Jubilee Novocherkasska, yield in 2013 from the Central zone of Krasnodar region. At the time of redy yield the combination of sweetness and acidity of fruits were favorable. The ratio of fructose to glucose was 1.69; 1.36; 2.00; 1.13, respectively, in grapes Aniuta, Vodograi, Nisina, Jubilee Novocherkasska. According to the percentage of fructose in fruit juice varieties Aniuta, Vodograi and Jubilee Novocherkasska close to each other (50.93; 56.14; 51.23%. According to the percentage of glucose similar varieties Aniuta and Nizina (33 - 34.27%, Vodograi and Jubilee Novocherkasska (41.16 - 45.22%. Sort Jubilee Novocherkasska, had content in berries close fructose and glucose. Most of fructose (66.02% in berries variety Nizina. In berries studied cultivars organic acid content was: wine 3128 - 3861, malic 982 - 3753, citric 109 - 317, amber 3 - 115 mg / dm3. The highest concentrations of potassium and sodium cations are presented in berries varieties Aniuta: potassium - 1219 sodium - 35.13 mg / dm3 and cations magnesium and calcium in berries Jubilee Novocherkasska 46.75 and 73.64 mg / dm3. The lowest concentration of potassium and sodium cations observed in grape Vodograi, magnesium - from grape Aniuta, calcium - at grape Nizina. We studied grape bunches are large, not dense, beautiful, berries are large, harmonious taste. Tasting score fresh grapes varieties Aniuta, Vodograi, Nizina, Jubilee Novocherkasska 7.6; 7.4; 7.8; 7.8 points respectively

  1. Using 3DClass To Flip Biochemistry Classroom

    T. Silva


    Full Text Available The flipped classroom inverts traditional teaching methods, in order to have studentsprepared for topics and techniques covered in the following meeting. This approach wasadopted in a biochemistry course taught to biology freshmen students at the University ofCampinas, using a Virtual Learning Environment called 3DClass. Before each classroomsession, a quiz was delivered covering the following topic and students were allowed totake quizzes as many times as they wanted. This approach was utilized in order to betterprepare students in classes and to perform lab experiments. Every student attempt wasrecorded in a database. Before each classroom session, the instructors were provided witha summary of the class answers, highlighting questions where students had more difficultyand the ones that scored higher. This kind of information was helpful to design activities tocover the topics where students had more difficulties. Based on the 3DClass records thestudents behaviors were mapped, such as students taking the quizzes seriously, studentsguessing, students answering a quiz until scoring 100%, students that continue answeringafter scoring 100% in order to increase their grades, students that never score 100%.However, the most relevant information 3DClass brought us was the possibility to identifystudent’s confidence in their answers, which could be observed by the analysis of theirattempts for each question. If they had made different choices each try, it would haveindicated a low confidence level, while always providing the same answer indicated ahigher confidence level, even whilst picking incorrect answers. This experiment haverevealed that students coming to the classroom better prepared reflected positively on thedeveloped activities, but the number of students taking the quizzes seriously were not asgreat as we had expected, indicating that more actions should be taken to improvestudents engagement with these activities.

  2. 76 FR 69029 - Delegation of Authority for the Office of the Chief Human Capital Officer


    ... Succession for the Office of the Chief Human Capital Officer; Notices #0;#0;Federal Register / Vol. 76 , No... Delegation of Authority for the Office of the Chief Human Capital Officer AGENCY: Office of the Secretary... all authority under the Chief Human Capital Officers Act of 2002 to the Chief Human Capital...

  3. The Biochemistry Over 20 Years In The High School Textbooks

    C. E.S. Rocha


    Full Text Available   The Biochemistry Over 20 Years In The High School Textbooks   Rocha, C. E. S.1; Büttenbender, M. D.1; Denardin, E.L.G.2, Roehrs, R.1,2 1Grupo Interdisciplinar de Pesquisa em Práticas de Ensino, UNIPAMPA, RS. 2Laboratório de Estudos Físico Químicos e Produtos Naturais, UNIPAMPA, RS.   INTRODUCTION: Many teachers make use of textbook to lead content in the classroom. The chemistry books introduce concepts that should relate biochemistry to students in schools. It is important that this first contact turns out into an encouraging experience for the students, because once it worked as expected it arouses interest and makes the students see themselves curious to delve into the subject. The research aims to evaluate the presence of related concepts in biochemistry textbooks in chemistry in high school, over 20 years. MATERIAL AND METHODS: In order to perform this study, we analyzed the following content related to biochemistry: proteins, carbohydrates, lipids and nucleic acids in the books "Chemistry - Structure of Matter and Organic Chemistry" of the year 1993 and the book "Chemistry in approach to daily life" of the year 2012 with the purpose of verifying the changes in the content of biochemistry in the last 20 years. RESULTS AND DISCUSSION: In the 90s, as used in the book, concepts and explanations are introduced in a very objective approach, making a total of 22 pages. The current largest is 23 pages with experiments and curiosities. Through analysis we found that current textbooks present the same issues related to biochemistry, however, a greater amount of data, bringing students to more examples and applications in everyday life. Today we see that the contents and processes are most exploited and that there is a concern on the importance of the study of issues that relate to biochemistry. CONCLUSIONS: The study of the biochemistry textbooks has been more attractive in recent years, contextualizing content with the daily life of

  4. The Biochemistry Show: a new and fun tool for learning

    A.H Ono


    Full Text Available The traditional methods to teach biochemistry in most universities are based on the memorization of chemical structures,  biochemical  pathways  and  reagent  names,  which  is  many  times  dismotivating  for  the  students.  We presently describe an innovative, interactive and alternative method for teaching biochemistry to medical and nutrition undergraduate students, called the Biochemistry Show (BioBio Show.The Biobio show is based on active participation of the students. They are divided in groups and the groups face each other. One group faces another one group at a time, in a game based on true or false questions that involve subjects of applied biochemistry (exercise, obesity, diabetes, cholesterol, free radicals, among others. The questions of the Show are previously elaborated by senior students. The Biobio Show has four phases, the first one is a selection exam, and from the second to the fourth phase, eliminatory confrontations happen. On a confrontation, the first group must select a certain quantity of questions for the opponent to answer.  The group who choses the questions must know how to answer and justify the selected questions. This procedure is repeated on all phases of the show. On the last phase, the questions used are taken from an exam previously performed by the students: either the 9-hour biochemistry exam (Sé et al. A 9-hour biochemistry exam. An iron man competition or a good way of evaluating undergraduate students? SBBq 2005, abstract K-6 or the True-or-False exam (TFE (Sé et al. Are tutor-students capable of writing good biochemistry exams? SBBq 2004, abstract K-18. The winner group receives an extra 0,5 point on the final grade. Over 70% of the students informed on a questionnaire that the Biobio Show is a valuable tool for learning biochemistry.    That is a new way to enrich the discussion of biochemistry in the classroom without the students getting bored. Moreover, learning

  5. Transport

    Transport is one of the major causes of environmental damage in Austria. Energy consumption, pollutants emissions, noise emissions, use of surfaces, sealing of surfaces, dissection of ecosystems and impact on landscape are the most significant environmental impacts caused by it. An overview of the transport development of passengers and freight in Austria is presented. Especially the energy consumption growth, carbon dioxide and nitrogen oxide emissions by type of transport, and the emissions development (HC, particle and carbon monoxide) of goods and passengers transport are analyzed covering the years 1980 - 1999. The health cost resulting from transport-related air pollution in Austria is given and measures to be taken for an effective control of the transport sector are mentioned. Figs. 8, Table 1. (nevyjel)

  6. Prof. John Wood, Chief Executive Designate, Dr Gordon Walker, Directorate, Chief Executive, Prof. Ken J. Peach, Head of the Particle Physics Department, CLRC Rutherford Appleton Laboratory, United Kingdom

    Patrice Loïez


    L. to. r.: Dr. Ian Wilson, CLIC Deputy Study Leader, Prof. Ken J. Peach, Head of the Particle Physics Department, Prof. John Wood, Chief Executive Designate, Dr. Gordon Walker, Directorate, Chief Executive

  7. The Eighth Stage of Information Management: Information Resources Management (IRM) vs. Knowledge Management (KM), and the Chief Information Officer (CIO) vs. the Chief Knowledge Officer (CKO).

    Chen, Rui


    Describes the characteristics of the transfer point of information management to knowledge management (KM), what information resources management (IRM) does, and compares information and knowledge management and the roles of chief information officer (CIO) and chief knowledge officer (CKO). (PEN)

  8. EDITORIAL: Incoming Editor-in-Chief

    Lidström, Suzanne


    , in his hands, the expansion continued and the transition to electronic production took place. In 2005, an agreement was signed with IOP Publishing and the bustling production work of the in-house team moved abroad to Bristol, leaving just the Editor-in-Chief to man the ship at the Royal Swedish Academy of Sciences. In 2011, however, as Roger prepared to step down, submissions had reached astounding levels as is evident from figure 1: that year, almost 1500 manuscripts were received by Physica Scripta, now acknowledged to be amongst the fastest growing journals in IOP Publishing, when measured in these terms. The year on year increase stands at 20% and, once again, of the extensive range of topics covered, condensed matter physics had been identified as the subject area in most need of attention because the burden of reviewing had become too great for one editor to oversee alone. Thus, when I joined Physica Scripta in January of this year, securing new External Editors for this field was perceived to be the most urgent task. It is, therefore, with the greatest of pleasure that I am able to announce the arrival of two new editors for this section: Professors David Keen and Tapio Rantala. Physica Scripta statistics Figure 1. The annual submissions made to Physica Scripta in recent years have rocketed and the rejection rate (given as a percentage) has increased rapidly. The modest increase in the number of articles accepted (shaded in blue) reflects a deliberate policy to augment the scientific quality. Professor Rantala has been selected by the Finnish Physical Society to replace Professor Matti Manninen, who is stepping down as the Finnish representative on the journal's Editorial Board. Professor Rantala is a prominent theorist and has been engaged in active research in a number of fields. In his early work, he was interested in surface science and molecular physics, however his expertise is predominantly in the domain of solid or materials physics related to


    P. X. Gomes


    Full Text Available Introduction: The current students generation are daily connected to the Internet, wich encourages the use of mobile tools in education. Many of the students of Biochemistry feel apprehensive about the discipline and the use of facebook may contribute, among other factors, motivating them. Objectives: It was analyzed the use of facebook as a mediator and motivator in the discipline of Biochemistry, basing on socioconstrutivist interventions. Material and methods: This work was developed in the action-research perspective, using the quali-quantitative method. An investigative questionnaire was used, using Likert scale and open questions, to investigate the facebook use, as well as the preferences of students, focusing on Biochemistry group in the Biomedicine course.  The posts were analyzed identifying: frequency of the interaction`s types (post, comment, likes;  interaction's categories (question, answer, motivational; and the content itself of the post. Results: It was highlighted students' interest to search materials, answering questions, and especially seeking information about the discipline. It was emphasized that the group was motivating for learning Biochemistry, encouragement the group to study, with quick and easy access to the professor by chat. Conclusions: The results indicate a preference for students at facebook, with a great motivational potential, is at easy access to colleagues, professor and monitor, or even the ease of obtaining the materials and ask questions in real time, indicating that this tool as a possible way, still little explored, to enhance the teaching of Biochemistry.

  10. Foreword from the Editor-in-Chief

    Jon M. Truby


    Highness the Emir, Sheikh Hamad bin Khalifa Al Thani, for this vision. I am grateful to all of those involved in the production of this and future issues, and hope the demands of our readers are met. May the journal continue to be a success. Dr. Jon M. Truby Ph.D, Editor-in-Chief

  11. An Integrated Biochemistry Laboratory, Including Molecular Modeling

    Hall, Adele J. Wolfson Mona L.; Branham, Thomas R.


    The dilemma of designing an advanced undergraduate laboratory lies in the desire to teach and reinforce basic principles and techniques while at the same time exposing students to the excitement of research. We report here on a one-semester, project-based biochemistry laboratory that combines the best features of a cookbook approach (high success rate, achievement of defined goals) with those of an investigative, discovery-based approach (student involvement in the experimental design, excitement of real research). Individual modules may be selected and combined to meet the needs of different courses and different institutions. The central theme of this lab is protein purification and design. This laboratory accompanies the first semester of biochemistry (Structure and Function of Macromolecules, a course taken mainly by junior and senior chemistry and biological chemistry majors). The protein chosen as the object of study is the enzyme lysozyme, which is utilized in all projects. It is suitable for a student lab because it is easily and inexpensively obtained from egg white and is extremely stable, and its high isoelectric point (pI = 11) allows for efficient separation from other proteins by ion-exchange chromatography. Furthermore, a literature search conducted by the resourceful student reveals a wealth of information, since lysozyme has been the subject of numerous studies. It was the first enzyme whose structure was determined by crystallography (1). Hendrickson et al. (2) have previously described an intensive one-month laboratory course centered around lysozyme, although their emphasis is on protein stability rather than purification and engineering. Lysozyme continues to be the focus of much exciting new work on protein folding and dynamics, structure and activity (3 - 5). This lab course includes the following features: (i) reinforcement of basic techniques, such as preparation of buffers, simple enzyme kinetics, and absorption spectroscopy; (ii

  12. Retirement of J. Gary Eden as Editor-in-Chief

    Jagadish, Chennupati; Jelinkova, Helena; Fainman, Yeshaiahu; Dawson, Martin; Ermers, Ysabel


    After nine years of dedicated service as Editor-in-Chief of Progress in Quantum Electronics (PQE), J. Gary Eden has retired at the end of December 2015. During his term as the Editor-in-Chief, PQE has grown significantly in size and quality and he has given generously of his time in advising authors, referees, editors, and the journal staff. Gary is an exceptional scientist and a generous individual who has given so much to the community. He is always very positive in every situation, and has created positive environment and supported people with utmost enthusiasm.

  13. Game Development as Didactic Strategy for Biochemistry Teaching

    G.G. Hornink


    It is well known that students and teachers have difficulties in learning and teaching Biochemistry due to its abstract and interconnected contents. This work proposes a didactic strategy in order to facilitate teaching and learning process in Biochemistry. The strategy was implemented with biological science undergraduate students. At first, the students were divided into groups with a specific topic to develop a game. During the semester, problem based learning cases, online activities like...

  14. Institute of Biochemistry and Biophysics. Research Report 1996-1997

    Scientific interests of the Institute of Biochemistry and Biophysics of the Polish Academy of Sciences have evolved from classical biochemistry, biophysics and physiological chemistry to up-to-date molecular biology. Research interests are focussed on replication, mutagenesis and repair of DNA; regulation of gene expression at various levels; biosynthesis and post-translational modifications of proteins; gene sequencing and functional analysis of open reading frames; structure, function and regulation of enzymes; conformation of proteins and peptides; modelling of structures and prediction of functions of proteins; mechanisms of electron transfer in polypeptides

  15. The Managerial Roles of Community College Chief Academic Officers.

    Anderson, Philip Wayne

    This study utilized Mintzberg's taxonomy of managerial roles to examine the roles performed by community college chief academic officers (CAOs). Mintzberg's taxonomy defines managerial roles as a set of behaviors and identifies 10 distinct roles: (1) figurehead; (2) leader; (3) liaison; (4) monitor; (5) disseminator; (6) spokesperson; (7)…

  16. The Chief Executive's Role in Human Resources Development

    Training, 1976


    This article gives the dialogue from a roundtable training discussion which answered questions concerning organizational human resources development (HRD), with emphasis on the chief executive officer's (CEO) role. The participants, who were management consultants and leaders in the HRD field, contributed 20 questions (which are included) that…

  17. Governors Face Political Hurdles in Seeking Power to Appoint Chiefs

    McNeil, Michele


    Convinced of the connection between the quality of their schools and the future of their states--not to mention their own political reputations--some governors are seeking a bigger role in shaping education policy by grabbing for more control over their state schools chiefs. Governors note that they are responsible for managing state budgets, of…

  18. September 2016 Letter to the Editor-in-Chief.


    Letter to the Editor-in-Chief of JOSPT as follows: "One More Cause of Failure to Validate a CPR: Overfitting" with Author's Response J Orthop Sports Phys Ther 2016;46(9):811-812. doi:10.2519/jospt.2016.0202. PMID:27581182

  19. The chief information security officer insights, tools and survival skills

    Kouns, Barry


    Chief Information Security Officers are bombarded with huge challenges every day, from recommending security applications to strategic thinking and business innovation. This guide describes the hard and soft skills that a successful CISO requires: not just a good knowledge of information security, but also attributes such as flexibility and communication skills.

  20. Chief Diversity Officers and the Wonderful World of Academe

    Harvey, William B.


    The chief diversity officer (CDO) position is new in the realm of higher education administration. Charged with helping their institutions become more diverse and inclusive, the people who occupy these positions face a variety of challenges as they attempt to modify change-resistant institutional cultures. Still, the emergence of the CDO position…

  1. Mitochondrial DNA mutations in oxyphilic and chief cell parathyroid adenomas

    Roth Sanford I


    Full Text Available Abstract Background The potential pathogenetic significance of mitochondrial DNA (mtDNA mutations in tumorigenesis is controversial. We hypothesized that benign tumorigenesis of a slowly replicating tissue like the human parathyroid might constitute an especially fertile ground on which a selective advantage conferred by mtDNA mutation could be manifested and might contribute to the oxyphilic phenotype observed in a subset of parathyroid tumors. Methods We sought acquired mitochondrial DNA mutations by sequencing the entire 16.6 kb mitochondrial genome of each of thirty sporadic parathyroid adenomas (18 chief cell and 12 oxyphil cell, eight independent, polyclonal, parathyroid primary chief cell hyperplasias plus corresponding normal control samples, five normal parathyroid glands, and one normal thyroid gland. Results Twenty-seven somatic mutations were identified in 15 of 30 (9 of 12 oxyphil adenomas, 6 of 18 chief cell parathyroid adenomas studied. No somatic mutations were observed in the hyperplastic parathyroid glands. Conclusion Features of the somatic mutations suggest that they may confer a selective advantage and contribute to the molecular pathogenesis of parathyroid adenomas. Importantly, the statistically significant differences in mutation prevalence in oxyphil vs. chief cell adenomas also suggest that mtDNA mutations may contribute to the oxyphil phenotype.

  2. Chief Nursing Officers: the past, present and future of nursing.

    Cummings, Jane; McArdle, Charlotte; McQueen, Fiona; White, Jean


    In celebration of International Nurses Day, Jane Cummings, Charlotte McArdle, Fiona McQueen and Jean White, Chief Nursing Officers (CNOs) for England, Northern Ireland, Scotland and Wales, reflect on the state of nursing in their respective countries, and what the future might hold for this rapidly evolving profession. PMID:27172492

  3. Suggested Performance Competencies for Chief Student Affairs Officers in Florida.

    Florida State Dept. of Education, Tallahassee.

    As an informational aid for Florida community college administrators, this manual outlines a set of performance competencies for chief student affairs officers (CSAO's). A professional mission statement for CSAO's is presented first, followed by a brief discussion of the use of the manual in writing job descriptions, selecting candidates for CSAO…

  4. Annual Report 2008 -- Office of the Chief Financial Officer (OCFO)

    Fernandez, Jeffrey


    It is with great pleasure that I present to you the 2008 Chief Financial Officer's Annual Report. The data included in this report has been compiled from the Budget Office, the Controller, Procurement and Property Management and the Sponsored Projects Office. Also included are some financial comparisons with other DOE Laboratories and a glossary of commonly used acronyms.

  5. Reclaiming the Educational Role of Chief Admission Officers.

    McDonough, Patricia; Robertson, Larry


    Describes changes that have occurred in high schools, colleges, and the entrepreneurial admission sector. Relates the evolution of the admission officer's job since the early 1960s and the profession's rapid growth. Details the hybrid role of marketer and educator for chief admissions officers, and issues a call for professional standards. (RJM)

  6. Chief Zibi Sidinane: Negotiating Moravian Christianity and Settlements in 'Nomansland'

    Henningsen, Anne Folke


    I artiklen analyseres de komplicerede forhandlinger, strategier og magtkampe, der knyttede sig til etablering af kristne missionsstationer i slutningen af 1800-tallet i det østlige Sydafrika. De implicerede herrnhutiske missionærer og konvertitter - som artiklens hovedperson Chief Zibi Sidinane -...

  7. Teaching of biochemistry: analyze of works presented in Congress the Society Brazilian Biochemistry and Molecular Biology - SBBq

    D.F. Escoto


    Full Text Available Introduction: In recent decades the strategies to improve science education has grown exponentially. Thus, the scientific production in the area is also growing, with the purpose of identifying parameters and methodologies that contribute to their qualification. The teaching of biochemistry is intimately linked to that context. However, it is still little explored in basic education and with character technicist in higher education. The aim of this study was identify areas that received most attention in the scientific literature about teaching and education in biochemistry that were presented at the Congress of the Brazilian Society of Biochemistry and Molecular Biology from 2004 to 2012. Material and Methods: To conduct the survey were analyzed summaries available on the website of the Brazilian Journal of Education for Biochemistry and Molecular Biology published in the proceedings of the event, where they were encontrados176 summaries. For expression of results was used categorization from the content analysis. Results and Discussion: The results observed to establish nine categories based on the analysis of the titles and content of the work, which, in descending order, were: information and communication technologies, alternative methods teaching and learning, biochemistry in Elementary Education and / or Medium, experiential activities, teacher training, dissemination of science, proposition and evaluation of content and / or science curricular and History and Philosophy. It is noticed that the three most important categories were consolidated along editions. In education, however, there was a significant decrease in the number of abstracts submitted abstracts for the past five years. Conclusions: We conclude that all categories listed seeking alternatives to improve teaching practices and promote education of biochemistry in different contexts.

  8. EDITORIAL: Outgoing Editor-in-Chief Outgoing Editor-in-Chief

    Hauptmann, Peter


    I started in 2002 as Editor-in-Chief of a well established journal—MST (Measurement Science and Technology). It was a time when modern means of communication offered new opportunities for the scientific community—for all scientists and engineers whether at universities, in industry or at other institutions—to access better quality information in a shorter time. This development helped us to be more efficient in our daily scientific work and to anticipate new trends faster than before. A flood of information was created by different search engines. A few online journals or journals published in emerging countries with a similar profile to MST appeared on the market. MST had to provide new answers in response to these developments. In 2002 I postulated two requirements to the journal. Firstly, the publisher has to be up to date. My impression over the years has been that IOPP is excellently organized. That has made it easier for the board members and all our reviewers to concentrate on the scientific aspects of our input to the journal. During all my visits to Bristol or my contacts with the IOPP staff I always met very professional and enthusiastic staff members. They have not only supported and encouraged the ideas and initiatives of the Editorial Board members, but they have also worked hard on establishing one of the most effective journal operations in the field of measurement science and technology. Many authors are well aware of this. Thus I am able to declare that the first requirement for a successful journal has been met. Secondly, the scientific level has to be high and the journal should attract readers from all over the world. This task was the responsibility of the Editorial Board members and of myself. Our strategy was on the one hand to ensure continuity in MST but on the other hand to be open to new trends and developments. Examples of these new aspects of the journal are fields like micro- and nanometrology, measurement techniques for

  9. The Use of Multiple Tools for Teaching Medical Biochemistry

    Se, Alexandre B.; Passos, Renato M.; Ono, Andre H.; Hermes-Lima, Marcelo


    In this work, we describe the use of several strategies employing the philosophies of active learning and problem-based learning (PBL) that may be used to improve the teaching of metabolic biochemistry to medical and nutritional undergraduate students. The main activities are as follows: 1) a seminar/poster system in a mini-congress format (using…

  10. An Integrated Strategy for Teaching Biochemistry to Biotechnology Specialty Students

    Ouyang, Liming; Ou, Ling; Zhang, Yuanxing


    The faculty of biochemistry established an integrated teaching strategy for biotechnology specialty students, by intermeshing the case-study method, web-assistant teaching, and improved lecture format with a brief content and multimedia courseware. Teaching practice showed that the integrated teaching strategy could retain the best features of…

  11. An "in Silico" DNA Cloning Experiment for the Biochemistry Laboratory

    Elkins, Kelly M.


    This laboratory exercise introduces students to concepts in recombinant DNA technology while accommodating a major semester project in protein purification, structure, and function in a biochemistry laboratory for junior- and senior-level undergraduate students. It is also suitable for forensic science courses focused in DNA biology and advanced…

  12. Osmotic Stressing, Membrane Leakage, and Fluorescence: An Introductory Biochemistry Demonstration

    Seu, Kalani J.


    A fluorescence demonstration is described that incorporates several fundamental aspects of an introductory biochemistry course. A variation of a known leakage assay is utilized to prepare vesicles containing a quenched fluorophore. The vesicles are exposed to several osmotic environments ranging from isotonic to hypotonic. The degree of vesicle…

  13. Ribose 5-Phosphate Isomerase Investigations for the Undergraduate Biochemistry Laboratory

    Jewett, Kathy; Sandwick, Roger K.


    The enzyme ribose 5-phosphate isomerase (RpiA) has many features that make it attractive as a focal point of a semester-long, advanced biochemistry laboratory for undergraduate students. The protein can easily and inexpensively be isolated from spinach using traditional purification techniques. Characterization of RpiA enzyme activity can be…

  14. Assessment of Learning Gains in a Flipped Biochemistry Classroom

    Ojennus, Deanna Dahlke


    The flipped classroom has become an increasingly popular pedagogical approach to teaching and learning. In this study, learning gains were assessed in a flipped biochemistry course and compared to gains in a traditional lecture. Although measured learning gains were not significantly different between the two courses, student perception of…

  15. Biochemistry Instructors' Perceptions of Analogies and Their Classroom Use

    Orgill, MaryKay; Bussey, Thomas J.; Bodner, George M.


    Biochemistry education relies heavily on students' abilities to conceptualize abstract cellular and molecular processes, mechanisms, and components. From a constructivist standpoint, students build their understandings of these abstract processes by connecting, expanding, or revising their prior conceptions and experiences. As such, biochemistry…

  16. Raising Environmental Awareness through Applied Biochemistry Laboratory Experiments

    Salman Ashraf, S.


    Our environment is under constant pressure and threat from various sources of pollution. Science students, in particular chemistry students, must not only be made aware of these issues, but also be taught that chemistry (and science) can provide solutions to such real-life issues. To this end, a newly developed biochemistry laboratory experiment…

  17. Uncovering Students' Incorrect Ideas about Foundational Concepts for Biochemistry

    Villafane, Sachel M.; Loertscher, Jennifer; Minderhout, Vicky; Lewis, Jennifer E.


    This paper presents preliminary data on how an assessment instrument with a unique structure can be used to identify common incorrect ideas from prior coursework at the beginning of a biochemistry course, and to determine whether these ideas have changed by the end of the course. The twenty-one multiple-choice items address seven different…

  18. Estimating foliar biochemistry from hyperspectral data in mixed forest canopy

    Huber Gharib, Silvia; Kneubühler, Mathias; Psomas, Achilleas;


    data to estimate the foliar concentration of nitrogen, carbon and water in three mixed forest canopies in Switzerland. With multiple linear regression models, continuum-removed and normalized HyMap spectra were related to foliar biochemistry on an individual tree level. The six spectral wavebands used...

  19. Differentiating Biochemistry Course Laboratories Based on Student Experience

    Jakubowski, Henry V.


    Content and emphases in undergraduate biochemistry courses can be readily tailored to accommodate the standards of the department in which they are housed, as well as the backgrounds of the students in the courses. A more challenging issue is how to construct laboratory experiences for a class with both chemistry majors, who usually have little or…

  20. Using Assessment to Improve Learning in the Biochemistry Classroom

    Loertscher, Jennifer


    In recent years, major drivers of undergraduate science education reform including the National Science Foundation (NSF) and the Howard Hughes Medical Institute (HHMI) have called on college and university instructors to take a more scientific approach to their teaching. Although many biochemistry instructors are gaining confidence in using…

  1. EDITORIAL: Farewell from the outgoing Editor-in-Chief Farewell from the outgoing Editor-in-Chief

    Rost, Jan Michael


    I am very pleased to announce that Professor Paul Corkum will be taking on the position of Editor-in-Chief at Journal of Physics B: Atomic, Molecular and Optical Physics (J. Phys. B) from the beginning of January 2011. During my term as Editor-in-Chief atomic, molecular and optical science has continued to change rapidly: we have seen ultracold physics widening its original emphasis on Bose-Einstein condensates to the entanglement of light and matter in the most general sense towards a science of information. At the same time attosecond science and interaction of matter with short x-ray pulses develops rapidly. I am very happy that J. Phys. B with Paul Corkum as Editor-in-Chief will play a central role in publishing exciting results from this field. I would like to thank the publishing team at J. Phys. B for their fantastic job, in particular for the quality of the refereeing system the team has been able to maintain while at the same time bringing down the publication times considerably. I thank them all for the help and support they have given me in the role of Editor-in-Chief and wish them the very best for the future. Last and certainly not least I would like to thank you, the authors, referees and readers, for the support of J. Phys. B.

  2. 76 FR 17658 - National Forum for State and Territorial Chief Executives (National Forum) Program Cooperative...


    ... HUMAN SERVICES Health Resources and Services Administration National Forum for State and Territorial Chief Executives (National Forum) Program Cooperative Agreement AGENCY: Health Resources and Services... Forum for State and Territorial Chief Executives (National Forum) Program Cooperative Agreement....

  3. Chief Liberal Arts Academic Officers: The Limits of Power and Authority.

    Lynch, David M.; And Others


    Results of a 1984 national survey of chief liberal arts academic officers (department heads, deans, and chief academic officers) are used to examine aspects of administrator careers and behavior, including grant administration, job satisfactions and frustrations, and career success. (MSE)

  4. Chief Human Capital Officers Council (CHCOC)'s Members and Assistants

    Office of Personnel Management — List of members of the Chief Human Capital Officers Council (CHCOC): Federal Chief Human Capital Officers (CHCOs) and Deputy CHCOs, as well as the council's chair,...

  5. DMPD: Type I interferon receptors: biochemistry and biological functions. [Dynamic Macrophage Pathway CSML Database

    Full Text Available 17502368 Type I interferon receptors: biochemistry and biological functions. de Wee...(.html) (.csml) Show Type I interferon receptors: biochemistry and biological functions. PubmedID 17502368 T...itle Type I interferon receptors: biochemistry and biological functions. Authors

  6. Biochemistry Students' Ideas about Shape and Charge in Enzyme-Substrate Interactions

    Linenberger, Kimberly J.; Bretz, Stacey Lowery


    Biochemistry is a visual discipline that requires students to develop an understanding of numerous representations. However, there is very little known about what students actually understand about the representations that are used to communicate ideas in biochemistry. This study investigated biochemistry students' understanding of multiple…

  7. Bioenergetics molecular biology, biochemistry, and pathology

    Ozawa, Takayuki


    The emergence of the Biochemical Sciences is underlined by the FAOB symposium in Seoul and highlighted by this Satellite meeting on the "New Bioenergetics. " Classical mitochondrial electron transfer and energy coupling is now complemented by the emerging molecular biology of the respiratory chain which is studied hand in hand with the recognition of mitochondrial disease as a major and emerging study in the basic and clinical medical sciences. Thus, this symposium has achieved an important balance of the fundamental and applied aspects of bioenergetics in the modern setting of molecular biology and mitochondrial disease. At the same time, the symposium takes note not only of the emerging excellence of Biochemical Studies in the Orient and indeed in Korea itself, but also retrospectively enjoys the history of electron transport and energy conservation as represented by the triumvirate ofYagi, King and Slater. Many thanks are due Drs. Kim and Ozawa for their elegant organization of this meeting and its juxtapo...

  8. Feasibility of an innovative third-year chief resident system: an internal medicine residency leadership study

    Kolade, Victor O; Staton, Lisa J.; Jayarajan, Ramesh; Bentley, Nanette K.; Huang, Xiangke


    Introduction: The role of the internal medicine chief resident includes various administrative, academic, social, and educational responsibilities, fulfillment of which prepares residents for further leadership tasks. However, the chief resident position has historically only been held by a few residents. As fourth-year chief residents are becoming less common, we considered a new model for rotating third-year residents as the chief resident.Methods: Online surveys were given to all 29 intern...

  9. Biochemistry on the Media: daily science in audio and video

    B. P. Melo et al


    Full Text Available Biochemistry on the Media: daily science in audio and video Melo,B. P1; Henriques, L. R1; Júnior, H. G2; Galvão, G. R2; Costa, M. M2; Silva, A. S3; Costa, M. P3; Barreto, L. P3; Almeida, A. A3; Fontes, P. P3; Meireles, L. M3; Costa, P. A3; Costa, C. B3; Monteiro, L. M. O3 Konig, I. M3; Dias, B. K. M1; Santos, R. C. V1; Bagno, F. F1; Fernandes, L1; Alves, P. R1; Sales, F. M1; Martins, T. C. N1; Moreira, V. J. V1; Marchiori, J. M1; Medeiros, L.4; Leite, J. P. V5; Moraes, G. H. K6.   1 Members of ETP-Biochemistry UFV; 2 Students of program Jovens Talentos para a Ciência UFV; 3 Graduating Students of ETP; 4 Coordinator in Espaço Ciência UFV; 5 Pharmaceutical, professor at Molecular Biology and Biochemistry Department (BBD UFV, ETP’s tutor; 6 Agronomist, professor at BDD, work’s advisor.   INTRODUCTION: The Educational Tutorial Program in Biochemistry (ETP from UFV have worked in qualification of basic science teachers, offering courses about Biochemistry. In courses, was detected the necessity of a personal material to inspire them. To do it, ETP compiled some media spots in a box and have used it in qualification courses. OBJECTIVES: The objective of this work was construct a part of a permanent material to be used in courses to qualifications high school's teachers and evaluate it. METODOLOGY: Applying questionnaires to high school students, ETP's members had detected that these students don't have a solid idea about how is Biochemistry. Thus, themes about common Biochemistry daily things were elected to be transformed in spots to radio and television. Texts about shampoo composition, vegetable’s darkening, bread’s fermentation, etc, were written and a script done by Journalism’s students of Espaço Ciência(*. Finally, the spots were recorded and vehiculated on universitary channel. In 2013, the spots were compiled in a media box. It has been included in a permanent material used in qualification courses. According to ALBAGLI

  10. 39 CFR 3004.60 - Chief Freedom of Information Act Officer.


    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Chief Freedom of Information Act Officer. 3004.60 Section 3004.60 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL PUBLIC RECORDS AND FREEDOM OF INFORMATION ACT § 3004.60 Chief Freedom of Information Act Officer. The Commission designates the Secretary of the Commission as the Chief...

  11. Wendell Flinchum to serve as interim chief of Virginia Tech Police

    Owczarski, Mark


    Lt. Wendell Flinchum, a 21-year veteran of the Virginia Tech Police Department, has been named the department's interim chief of police effective July 1. Flinchum's appointment follows the resignation of Chief Debra Duncan, who will leave the university to become police chief for the City of Monroe, N.C.

  12. 76 FR 69031 - Order of Succession for the Office of the Chief Human Capital Officer


    ... URBAN DEVELOPMENT Order of Succession for the Office of the Chief Human Capital Officer AGENCY: Office of the Chief Human Capital Officer, HUD. ACTION: Notice of order of succession. SUMMARY: In this... the Order of Succession for the Office of the Chief Human Capital Officer. DATES: Effective...

  13. 76 FR 53938 - Order of Succession for the Office of the Chief Procurement Officer


    ... URBAN DEVELOPMENT Order of Succession for the Office of the Chief Procurement Officer AGENCY: Office of the Chief Procurement Officer, HUD. ACTION: Notice of Order of Succession. SUMMARY: In this notice, the Chief Procurement Officer designates the Order of Succession for the Office of the...

  14. 76 FR 67472 - Order of Succession for the Office of the Chief Information Officer


    ... URBAN DEVELOPMENT Order of Succession for the Office of the Chief Information Officer AGENCY: Office of the Chief Information Officer, HUD. ACTION: Notice of Order of Succession. SUMMARY: In this notice... Order of Succession for the Office of the Chief Information Officer. This Order of Succession...

  15. 75 FR 11940 - Office of the Chief Human Capital Officer; Information Collection; Ancestry and Ethnicity Data...


    ... NATIONAL INTELLIGENCE Office of the Chief Human Capital Officer; Information Collection; Ancestry and... the Chief Human Capital Officer, ODNI, at Washington, DC 20511, or call 703-275-3369. Please cite... submitted on or before April 12, 2010. FOR FURTHER INFORMATION CONTACT: The Office of the Chief...

  16. Army Chief of Staff Gen. George Casey Addresses NPS Community

    Naval Postgraduate School Public Affairs Office


    Naval Postgraduate School students, staff and faculty gathered to see Army Chief of Staff General George W. Casey offer a hopeful and focused look at the future of the Army and its role in the big picture of the U.S. military. During his visit on May 13 as a Secretary of the Navy Guest Lecturer, Casey expressed his gratitude for the men and women in uniform, and the challenges they continue to face.

  17. Chief Marketing Officer and the Challenge of Digital Maturity

    PURCAREA, Ioan Matei; NEGRICEA, Costel Iliuta


    Digital is the new normal today, the digitally transformation allowing step by step a closer connection with customers, and accordingly answer to the new requirements of the supply chain management. The rules of engagement are changed by the digital lives of customers, the digital leaders creating value across physical/digital products, services, and experience. Chief Marketing Officer (CMO) is proving a more devoted personal attention and a more directly involvement in digital initiatives, t...

  18. Second ASEAN Chief Justices’ Roundtable on Environment: The Proceedings

    Asian Development Bank


    From 7–10 December 2012, Association of Southeast Asian Nations (ASEAN) chief justices and their designees convened in Melaka, Malaysia for their second roundtable on environment. The roundtable provided a forum for experts to discuss common ASEAN environmental challenges and for ASEAN judges to share their experiences in handling environmental challenges. Towards the end, the participants discussed the draft Melaka Memorandum of Understanding for Cooperation among ASEAN Courts, which aims to...

  19. Department of Defense implementation of the Chief Financial Officer Act.

    Shields, James L.


    Approved for public release; distribution is unlimited. This thesis analyzes the provisions of the Chief Financial Officers (CFO) Act of 1990 as they apply to the Department of Defense (DOD). It identifies the background environment in which the CFO Act was formulated and the steps that DOD is taking to implement the law. Particular attention is given to the development of the federal financial management improvement process, including congressional committee hearings and ar...

  20. Succession planning: perspectives of chief executive officers in US hospitals.

    Collins, Sandra K


    A study was conducted to explore the perceptions of chief executive officers in US hospitals regarding the origins of leadership and how they felt about internally developed successors versus externally recruited successors. Furthermore, the study examined how this group of executives utilizes the succession planning process, what factors impact successor identification, what positions are applicable for succession planning activities, and who is ultimately held responsible for leadership continuity within the hospital industry. PMID:19668068

  1. CNPC Appoints Chief Experts for Important Technological Projects

    Zhao Jianzhong


    @@ On June 27th, China National Petroleum Corporation (CNPC) held a public recruitment to appoint chief experts in Beijing for its important technological projects, which is the first time for CNPC to appoint chief managers by the means of competitive recruitment. This recruitment covers four projects, such as drilling, logging, geophysical survey and ground engineering with 15 projects. Of those,there are 8 drilling projects, which make up 50 percent of all the important technological projects for public recruitment. CNPC expects to further boost the chief expert responsibility system and promote the research and development (R&D) of technological project on the basis of the public recruitment. The company completes the recruitment following the procedure of making announcement, conducting competitive recruitment and giving publicity. On July 25th, the appointment ceremony was held by CNPC and 15 experts were awarded the certificates. CNPC is entering a new stage for the implementation of the technology and talent strategy for the 11th Five-Year Plan. What's more, a new management mode is taking shape for the technological project and for the construction of technological personnel pool.

  2. EDITORIAL: Farewell from the outgoing Editor-in-Chief

    Burnett, Keith


    I am very pleased to announce that Professor Jan-Michael Rost will be taking on the position of Editor-in-Chief at Journal of Physics B: Atomic, Molecular and Optical Physics (J. Phys. B) from the beginning of January 2005. As Editor-in-Chief I have seen the journal respond to the rapid and exciting developments in atomic, molecular and optical physics of recent years. There will, I am sure, be a great deal of new and important science in our field in the years ahead. I am also sure that Jan-Michael will do a fantastic job in guiding the journal through these times. The publishing team at J. Phys. B is a superbly responsive and effective one that does a great job in publishing the science we do. I want to thank them all for the help and support they have given me in the role of Editor-in-Chief and wish them the very best for the future. Last and certainly not least I would like to thank you, the authors, referees and readers, for making J. Phys. B such a great journal to have been a part of.

  3. EDITORIAL: Incoming Editor-in-Chief Incoming Editor-in-Chief

    Birch, David


    It is a pleasure and an honour for me to be taking over as Editor-in-Chief of Measurement Science and Technology. MST is well known across research communities worldwide as a leading journal in which to publish new techniques and instrumentation. It has gained this enviable position largely because of the excellent guidance of its Editorial Board and dedicated staff at Institute of Physics Publishing over many years. I want to highlight in particular the contribution of the outgoing Editor Peter Hauptmann, and other Editors before him, in making the journal truly international. We thank Peter immensely for all his hard work in leading the journal, having exceptionally served two terms, each of five years. I come into the post of Editor at a very interesting and challenging time for research. The global recession is leading to cuts in research funding in many countries, researchers and their outputs are coming under closer scrutiny than ever before, and more is being expected of them. Journals play a critical role in monitoring and maintaining research standards, but we should be careful not to assume that journal Impact Factor is the sole measure of research quality. Although expediency may sometimes demand it, Impact Factor, as practitioners know, is subject dependent. One of the great things about science and technology for me is its level playing field. The key point is still innovation no matter where the work is done or where it is published. MST has a long pedigree of being the natural home of the highest quality papers from leading researchers wishing to report novel instrumentation and techniques. 2013 will mark the 90th anniversary of MST and we look forward to celebrating in style its sustained success. I recall with pride the first paper I published in Journal of Physics E: Scientific Instruments (as MST was previously titled) back in 1977. The paper reported the design and application of an early fluorescence lifetime spectrometer that I had constructed

  4. New clinical executive models: one system's approach to chief nursing officer-chief medical officer co-leadership.

    Patton, Pat; Pawar, Manoj


    The current complex and rapidly changing health care environment calls for new approaches to leadership, particularly for clinical leaders as they assume greater responsibility for identifying and managing the clinical leverage points that create value. The chief nursing officer-chief medical officer dyad as a co-leadership model is one such approach. Catholic Health Initiatives is a large, complex health care system in the United States that has embraced this partnership-based model. On the basis of Catholic Health Initiatives experience, attention to the design of such partnerships is critical for their success, and a number of guiding principles have emerged. In addition, leadership development interventions, with attention to both the individual and the partnership, can play a critical role in supporting the evolution of strong and effective clinical dyads. PMID:22955220

  5. Biochemistry and evolutionary biology: Two disciplines that need each other

    Athel Cornish-Bowden; Juli Peretó; María Luz Cárdenas


    Biochemical information has been crucial for the development of evolutionary biology. On the one hand, the sequence information now appearing is producing a huge increase in the amount of data available for phylogenetic analysis; on the other hand, and perhaps more fundamentally, it allows understanding of the mechanisms that make evolution possible. Less well recognized, but just as important, understanding evolutionary biology is essential for understanding many details of biochemistry that would otherwise be mysterious, such as why the structures of NAD and other coenzymes are far more complicated than their functions would seem to require. Courses of biochemistry should thus pay attention to the essential role of evolution in selecting the molecules of life.

  6. Current research in Radiation Biology and Biochemistry Division

    The Radiation Biology and Biochemistry Division, Bhabha Atomic Research Centre, Bombay has been engaged in research in the frontier areas of (i) radiation biology related to tumour therapy and injury caused by free radicals; (ii) molecular basis of diseases of physiological origin; (iii) molecular aspects of chemical carcinogenesis and (iv) structure of genome and genome related functions. The gist of research and development activities carried out in the Division during the last two years are documented

  7. A biochemistry laboratory course designed to enhance students autonomy

    T. Silva


    Full Text Available INTRODUCTION: Laboratory sessions are responsible for promoting instrumentation skills desirable in biochemistry and biochemistry related careers. They are traditionally based on experimental protocols that lead to the expected results, and students usually have not autonomy to plan and execute their experiments. GOALS: This work aimed to enhance a traditional biochemistry lab course, applying pre-lab quizzes on protein biochemistry and lab techniques in order to have students better prepared to plan, execute and interpret experiments. This approach also aims to bring the laboratory sessions into an inquiry-based environment capable to improve students’ independent capabilities in 2 autonomy domains: learning and communication. MATERIAL AND METHODS: Online quizzes are delivered one week before each laboratory session, containing questions regarding the experimental techniques and theoretical basis related to them. Laboratory activities are presented in an inquiry-based approach where the first class of each activity is dedicated to plan experiments in order to answer the research questions presented by instructors. Activities are also organized in order to enhance students’ autonomy. The first activity is the simplest and more instructor-controlled and the last one is the most complex and less driven, transferring gradually to students the responsibility for their decisions in laboratory, supporting students’ autonomy. RESULTS: Online quizzes allowed instructors to identify students’ difficulties and to timely intervene. Scientific reports presented by students at the end of each activity showed that they performed better on less driven activities in which autonomy support were more complex than in the instructor controlled activities. CONCLUSIONS: Scientific reports analysis reveals students capabilities related to different scopes of autonomy, such as: discuss different strategies; find multiple solutions to solve problems; make their

  8. Postprandial biochemistry changes in penguins (Spheniscus demersus) including hyperuricemia.

    Cray, Carolyn; Stremme, Donald W; Arheart, Kristopher L


    In a clinical setting, it is important to differentiate abnormal values that may be a normal change resulting from feeding and those that may be disease related. Such postprandial changes have been identified in mammalian and avian species. In the current study, pre- and postvalues for several routine biochemical analytes from penguins (Spheniscus demersus) were examined. Significant increases were found in uric acid, triglycerides, and bile acids (P abnormal biochemistry values in penguins. PMID:20597226

  9. The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders.

    Houten, Sander M; Violante, Sara; Ventura, Fatima V; Wanders, Ronald J A


    Mitochondrial fatty acid β-oxidation (FAO) is the major pathway for the degradation of fatty acids and is essential for maintaining energy homeostasis in the human body. Fatty acids are a crucial energy source in the postabsorptive and fasted states when glucose supply is limiting. But even when glucose is abundantly available, FAO is a main energy source for the heart, skeletal muscle, and kidney. A series of enzymes, transporters, and other facilitating proteins are involved in FAO. Recessively inherited defects are known for most of the genes encoding these proteins. The clinical presentation of these disorders may include hypoketotic hypoglycemia, (cardio)myopathy, arrhythmia, and rhabdomyolysis and illustrates the importance of FAO during fasting and in hepatic and (cardio)muscular function. In this review, we present the current state of knowledge on the biochemistry and physiological functions of FAO and discuss the pathophysiological processes associated with FAO disorders. PMID:26474213


    A.B. Sé


    Full Text Available The pros and cons of Problem Based Learning (PBL have been extensivelydiscussed in the literature. We describe PBL-like strategies used at UnB (some ofthem since 1999 that may be useful elsewhere to improve undergraduatebiochemistry teaching with clinical applications. The main activities are: (i aseminar/poster system, (ii a true-or-false applied biochemistry exam (prepared bypeer tutors, (iii a 9-hour-exam on metabolism (based in actual papers, (iv anAdvanced Biochemistry course (directed to peer tutors, (v pizza-and-pasta (formetabolism teaching and free radicals (real science for students experiments,(vi the BioBio blog (, (vii student lectures onhealth issues directed to the community, and (viii the BioBio Show. The mainobjective of these activities is providing students with a more practical andentertaining approach to biochemistry using philosophic PBL principles such asthe application of basic knowledge to real situations (diseases, experiments andscientific discoveries. We also emphasize (a the importance of peer-tutor activityfor optimized learning of students and peer tutors, (b the relevance of a closerinteraction between students and professors, and (c the necessity to initiatestudents precociously in actual basic/medical science and contact with the public.Most activities have been evaluated by the students through written questionnairesand informal conversations, for several semesters, indicating good acceptanceand approval of these methods.

  11. Game Development as Didactic Strategy for Biochemistry Teaching

    G.G. Hornink


    Full Text Available It is well known that students and teachers have difficulties in learning and teaching Biochemistry due to its abstract and interconnected contents. This work proposes a didactic strategy in order to facilitate teaching and learning process in Biochemistry. The strategy was implemented with biological science undergraduate students. At first, the students were divided into groups with a specific topic to develop a game. During the semester, problem based learning cases, online activities like crossword puzzle, essay questions and educational softwares were used to present the content of each topic. The groups were oriented in classroom and online, to choose and organize contents and create ways to approach them in games. At the end of the course the groups played each other games, which were evaluated by teacher and students following some criteria like: creativity, content organization, interdisciplinarity, proposal coherence, instructions clarity, specific content. The game elaboration contributed to the development of social and cognitive functions, such as teamwork and troubleshooting, providing an interesting perspective to the student about knowledge construction process. The strategy showed up students' creativity and ability to reorganize their knowledge to a different education level. In an overview, the results indicate that the proposed didactic strategy is an effective way to enhance learning and to motivate students into Biochemistry topics.

  12. Research on the actual condition on the licensed chief engineers of radiation

    A research on the actual condition on the licensed chief engineers of radiation was performed on October, 1975. Question cards were sent to 2915 facilities in Japan, and answers came back from 2850 facilities. Answers report the size of each facility, number of employee, number of chief engineers in charge, age of chief engineers, appointment authority, responsibility, improvement of working condition of chief engineer, and assistant officer for chief engineer. The number of worker is 62,456 in 2,769 facilities. The number of chief engineer in charge is 3,286 containing 579 doctor and/or dentist. The age of chief in 80 percent facilities is above 31. System of management of radiation safety was also investigated. (Kato, T.)

  13. Are tutor-students capable of writing good biochemistry exams?

    Sé Alexandre B.


    Full Text Available In a previous article we described the relevance of student seminars for the learning process of appliedbiochemistry for medical and nutrition students (Hermes-Lima et al., Biochem. Mol.Biol.Educ. 30:30-34,2002. First semester students of a basic biochemistry course (BioBio are divided in 10 groupsof 5 members, and each group is assigned to a specic topic (diabetes, cholesterol, etc under thesupervision of a tutor-student. The tutors have already coursed BioBio and are currently undertakingan advanced biochemistry course. In order to evaluate the learning of applied biochemistry for BioBiostudents a true or false exam (TFE is performed. This exam is made of 50 questions (5 on eachtopic elaborated by the tutors under the supervision of the teacher. The TFE corresponds to 10percent of the grade of BioBio and focus on clinical and/or applied biochemistry situations. At theend of the exam, BioBio students were asked to share their opinions about TFEs (n = 401, from2001/1 to 2003/2. When asked to give a 0-to-4 score regarding (a the diculty level of the test,(b the technical quality and (c if the exam makes an appropriate evaluation of applied biochemistryknowledge, the scores were 2.9, 3.4 and 2.9, respectively. BioBio students were also asked if they ndvalid to be evaluated by a tutor-made exam and if they would like to participate in the making ofTFEs; 96 and 58 percent answered yes, respectively.In another survey, we interviewed former BioBio students from the 2nd to the 7th semesters (n=95about TFEs (since 1999-1 regarding technical aspects, which included (1 clarity of questions, (2 levelof diculty, (3 clinical application and (4 thinking (as opposed to memorizing abilities demanded;the 0-to-4 scores were 3.1, 2.9, 2.6, and 2.5, respectively. Other four questions were on the validityof tutors writing TFEs and their capacity to perform such a task; the average score was 3.2. Oursurveys show the students good acceptance of the seminar system

  14. Corporate identity of the Chief Mines Inspectorate of Brandenburg

    The mining administration of the Land Brandenburg abandoned its traditional self-image in order to be able to cope with the challenges presented by a modern and future-oriented mining industry. The reinstatement of the Chief Mines Inspectorate of the Land Brandenburg opened up a chance of breaking up obsolete administrative structures and, instead, giving this entity a Corporate Identity as its foundation. The inspectorate considers Corporate Identity as the way of making its work understood both internally and to the exterior. (orig.)

  15. Letter from the New Editor-in-Chief

    Pabulo Henrique Rampelotto


    Full Text Available It is my great pleasure to serve as the new Editor-in-Chief of Life, a journal concerned with fundamental questions on the origins and nature of life, evolution of biosystems and astrobiology. With my experience as Executive Editor, Senior Editor and Guest Editor of so many successful special issues (some of them in MDPI journals [1–6], I am committed to making the journal a success, with the launch of exciting special issues, publication of high quality papers, as well as inclusion of the journal in major indexing and abstracting services. In this editorial, I present my view and plans for the journal.

  16. Introducing the New JETWI Editor-in-Chief

    Sabah Mohammed


    As my four-year term as the founding editor of the Journal of Emerging Technologies in Web Intelligence (JETWI ISSN 1798-0461) ends in Feb 2013, it gives me great pleasure to introduce my longtime friend and colleague Dr. Simon Fong as the next Editor-in- Chief of JETWI.  Dr. Fong is a Professor of Computer and Information Science at the University of Macau and among the founding members of the Data Analytics and Collaborative Computing Research Group in the Faculty of Science and Techno...

  17. A Review of Chief Information Officer' Main Skills

    Portela, Luis; Carvalho, Roberto; Varajão, João; Magalhães, Luis

    Information Systems are transforming our lives. Their social and economic impact means opportunities and challenges for people, organizations and governments. Being decisive for competitiveness, they are more and more taken in account by companies, which look at them in order to find a way of improving the business. In this context, the CIO (Chief Information Officer) has a central role, and needs to perform several tasks to ensure that information systems under his supervision are efficient. To be competent in his job, the CIO needs several skills. In this paper, the CIO's main skills are identified and discussed.

  18. A Plot Story:The Ransom of Red Chief

    WANG Si-yu


    The Ransom of Red Chief is a short story written by O · Henry. Some critics regard it as a plot story but some do not. A typical plot story should focus on the plot:using techniques such as flashback or foreshadowing to unfold the plot and containing exposition, complication, climax, resolution, conclusion to rich the plot. The main characters are presented with internal and ex⁃ternal conflicts as well. In this thesis, a detailed analysis will be presented to prove that this story is really a plot story.

  19. Comparative analysis of the biochemistry undergraduate courses in Brazil

    P. A. Granjeiro


    Full Text Available INTRODUCTION: The economic and social development of Brazil during the recent decades has contributed to the installation of several new undergraduate and graduate study programs, as is the case of the undergraduate biochemistry programs at UFV, UFSJ and UEM. The new biochemical professionals are being prepared to work mainly in Industries, research Institutes, government agencies and Universities in all fields that involve Biochemistry and Molecular Biology. The aim of this study was to conduct a comparative analysis of the courses in Biochemistry in Brazil. MATERIAL AND METHODS: Comparative analysis of the course units of the UFV, UFSJ and UEM programs, centered on the curricula contents and organization and on the profiles of the students in terms of parameters such as the number of admissions and the graduation completion rates. RESULTS AND DISCUSSION: The UFV and UEM programs present a very similar distribution of workload over the biological, exact sciences, humanities, biochemical specialties and technological applications. The UFSJ program presents higher workloads in the areas of biological sciences and technological applications. No significant differences in the distribution of the workloads of mandatory and optional disciplines, complementary activities and supervised activities were detected. Over the past five years there was a decrease in the number of students that abandoned the programs, despite the increased retention time in the three courses. Most graduated students at both UFV and UFSJ continue their academic career toward the Master or Doctor degrees. CONCLUSION: Little difference between the study programs analyzed. This is somewhat surprising if one considers the fact that individual conception of each program was based on different local conditions and needs, which indeed justify small differences. The similarity of the programs, on the other hand, reflects the universality of the biochemical sciences and their broad

  20. Re-Attitude of Biochemistry Laboratory Course Contents in Medical, Dentistry and Para-Medical Faculties

    Durdi Qujeq; Iman Jahanian; Mohsen Tatar; Naghmeh Abbassi; Korosh Rasolpour


    Regarding to development of basic science and new methods in biochemistry in recent years, practical biochemistry contents should be optimized (1). Therefore, re-attitude biochemistry course contents in medical schools has paralleled worldwide trends a moved from current status is needed (2, 3). As reported by investi-gators many medical schools around the world have reformed their medical curriculum in recent years (2). Many authors are convinced that students learn more effectively if the k...

  1. International Symposium on Insect Physiology, Biochemistry and Molecular Biology


    @@ We are building on the success of the Sixth Chinese Insect Physiology, Biochemistry and Molecular Biology Symposium, Beijing, held in 2005. The 2005 symposium saw many Chinese and international authorities share their expertise in a broad range of insect science, including analyses of insect genomes and proteomes, functional gene expression and regulation during development, insect immunity, insect neurobiology, insect-host interactions and insect chemical communication. The coming symposium, which will be held in Shandong University,Jinan, Shandong province, September 19-22, 2007, will offer material along similar lines.

  2. Application of 15N in biochemistry, agriculture and medicine

    The compendium on application of 15N in the biosciences comprises 7 chapters. The 1st chapter comprehends introductory remarks on isotopes in general and on nitrogen isotopes in particular. In the 2nd chapter fundamentals of 15N tracer techniques are discussed. The 3rd chapter deals with experiment programs and the evaluation of experiments. The methodology of sample preparation as well as of isotope analysis is treated in chapter 4. The chapters 5 to 7 deal with the application of 15N as tracer in biochemistry, agricultural research and medicine, resp. Relevant literature is added to each chapter

  3. Virtual Biochemistry – pH effect on enzyme activity

    D.N. Heidrich; R.V. Antônio; M.S.R.B. Figueiredo; J.K. Sugai; J.A.P. Angotti


    Protocols of laboratory experiments, followed by teacher's explanation, not always clearly translate to the student the dynamics to beadopted for the implementation of the proposed practice. One of these cases is related to the study of the effect of pH on enzyme activity. For better help the understanding of the technical procedure, a hypermedia was built based on a protocol adopted at the Department of Biochemistry, UFSC. The hypermedia shows how theeffect of variations in pH can be observe...

  4. Construction of concept maps as tool for Biochemistry learning

    Silvia Lopes de Menezes


    Full Text Available The use of concept maps on the teaching of sciences has been object of worldwide research with different purposes: to detect the previous knowledge of the students on certain topics or to evaluate learning, among others. Based on Ausubel´s cognitive psychology, concept maps assume that the learning is accomplished by assimilation of new concepts and propositions to the students´ cognitive structure, contributing to establish links between the previous and new knowledge. It is especially interesting on the approach of interdisciplinary issues, as many studied in Biochemistry.The relevance of the use of concept maps on biochemistry learning was evaluated on a thirty-hour undergraduation optional course, with interdisciplinary topics, which are not usually included on introductory Biochemistry courses. The course Biochemistry of Animal Venoms was structured in seven module where the biochemical action mechanisms of the venoms of Crotalus sp (south american rattlesnake, Bothrops sp (jararaca, Loxosceles sp (brown spider, Tityus sp (yellow scorpion, Phoneutria sp (armed spider, Apis mellifera (honey bee and Latrodectus sp (black widowwere discussed. The students worked in small groups and, at each module, there were (1 an oriented study, guided by questions, texts and schemes, supervised by the teachers, (2 the construction of individual concept maps, where the local and systemic effects of the venoms should be predicted by their biochemical composition and (3 the construction of a new map by the group, incorporating the information of the individual maps. The difficulty level of these tasks was gradually increased throughout the course, with lesser time to carry out the tasks, lesser assistance during the oriented study and even lesser information on the venom effects.The course assessment was given by the number, quality and correction of the concepts relationship present in the concept maps, through a questionnaire and by the

  5. A guide on instrument of biochemistry and molecular biology

    This book is about instrument on biochemistry and molecular biology, which consists of six chapters. It deals with introduction of advanced bio-instrument, common utilization and maintain, explanation of each instrument like capillary electrophoresis, interactive laser cytometer, personal computer and software, an electron microscope and DNA/RNS synthesis instrument, large equipment and special system like information system and network, analysis system for genome and large spectro graph, outside donation, examples for common utilization and appendix on data like application form for use.

  6. Construction of Hypertexts in a Biochemistry Pos- Graduation Discipline

    W. B. Maia; B.S. dos Santos; J. M. Martins; B.C. Araujo; A.A. Pimenta Filho; Araújo, T. G.; Martins, M.C.; C.R.F.C. Mota; A.L. Castro- Neto; V.L.M. Lima,


    Virtual reality is an innovating manner of comprehending and acting on how the world is and, also, considered a new way of intellectual exercise.  This work took place in a  biochemistry masters discipline (Advanced Formation in ScientificEducation) and had as its observation context the forum (on-line tool) viability, intending the construction of hypertexts (active  collaborative writing ) by the 15 registered students in the  discipline in 2008. The discipline was available on the web, in ...

  7. Oxidative Damage and Suppression: an Experimental Approach to Teaching Biochemistry

    Isa G. J. de Avellar; Luana T. Dalvi; Lorena M. R. Mascarenhas; Alexandre B. Sé; Marcelo Hermes-Lima


    Experimental Biochemistry is a challenging and worthy didactical  task:  a vast field with many different techniques.   Radical mediated biooxidative processes, implied in aging and accompanying various pathologies,  have an enormous  appeal  to public in general and particularly to students in the science field.   The  Fenton  reaction,   first  reported by  the 22-year  old Cambridge  chemistry  undergraduate Henry J. H. Fenton  (Chemical  news vol. 33 page 190, 1876), is a useful in vitro ...

  8. Poster Display as an Alternative Evaluation Method to Biochemistry Teaching

    Silas P. Rodrigues


    Full Text Available Biochemistry is present in dierent professional under gradation courses in which it seeks to attendseveral objectives. The discipline oered to the students of Biology Science Course at UFES is tra-ditionally organized in a series of lectures to the basic information, a laboratory class related to eachtopic and a three written tests. Our students, as many from other courses, study biochemistry justbecause they have to. The teacher can alter the student behavior by changing the way in which theyexamine them. This work describes and analyses the experience of using poster display as an assess-ment and includes feedback from the students and teachers. At the beginning of the term the activityis explained to the class and groups are formed. They are oriented to search a full research paper, with\\metabolism as a key word. During the students presentation, teachers and graduation studentsevaluate the production of a self-explanatory poster, assurance in the chosen work and involvementof all components of the group. A multiple-choice questionnaire was applied to 15-30 students fromthe ve classes that had already done the activity. The teachers and the graduation students also hadtheir opinions heard. 62.3 % of the students agreed that the activity accomplishes its objective tostimulate the integration of general knowledge and comprehension of a specic scientic work, while itpromotes the practice of presentation at seminars. 62.2 % believed that it allows the learner to showits knowledge in a better way and 51 % of the students were very much motivated within the activity.For 91.2 % of the students, they should choose the article, as it allows a better correlation betweenbiochemistry and personal anities (42.7 %. Also, 98 % believed that the activity should be carriedout in groups, because it allows a deeper discussion (53.6 %, stimulate group activities (20 % orpermits the materials costs division (22 %. Only 1.8 % of the learners thought that the

  9. 78 FR 4170 - License Amendment Request for Analytical Bio-Chemistry Laboratories, Inc., Columbia, MO


    ... COMMISSION License Amendment Request for Analytical Bio-Chemistry Laboratories, Inc., Columbia, MO AGENCY... issuance of a license amendment to Materials License No. 24-13365-01 issued to Analytical Bio-Chemistry... Electronic Reading Room at . From this site, you can access the...

  10. What Are the Appropriate Curriculum Contents for Biochemistry Courses in Veterinary Medicine?

    Correia, A. A. D.; Correia, J. H. R. D.


    Presents an overview of the important items that the author's suggest should be included in a biochemistry course given to students in veterinary medicine. Presents a broad range of specific topics in biochemistry and strategies for covering as many topics as possible in one course. (LZ)

  11. A Curriculum Skills Matrix for Development and Assessment of Undergraduate Biochemistry and Molecular Biology Laboratory Programs

    Caldwell, Benjamin; Rohlman, Christopher; Benore-Parsons, Marilee


    We have designed a skills matrix to be used for developing and assessing undergraduate biochemistry and molecular biology laboratory curricula. We prepared the skills matrix for the Project Kaleidoscope Summer Institute workshop in Snowbird, Utah (July 2001) to help current and developing undergraduate biochemistry and molecular biology program…

  12. Case Study of How Turkish University Students Improve Their Biochemistry Achievement

    Sadi, Özlem


    Biochemistry courses have an important place as a common subject in faculties of medicine, food engineering, biology and chemistry. MSLQ, Metacognitive Awareness Inventory and Learning Approach Questionnaire were used. The study also involves repeated observations of the same instructor in a biochemistry class over eight weeks to describe…

  13. Teaching Arrangements of Carbohydrate Metabolism in Biochemistry Curriculum in Peking University Health Science Center

    Chen, Hao; Ni, Ju-Hua


    Biochemistry occupies a unique place in the medical school curricula, but the teaching of biochemistry presents certain challenges. One of these challenges is facilitating students' interest in and mastery of metabolism. The many pathways and modes of regulation can be overwhelming for students to learn and difficult for professors to teach…

  14. Combining Content and Elements of Communication into an Upper-Level Biochemistry Course

    Whittington, Carli P.; Pellock, Samuel J.; Cunningham, Rebecca L.; Cox, James R.


    This report describes how a science communication module was incorporated into an advanced biochemistry course. Elements of communication were taught synergistically with biochemistry content in this course in an effort to expose students to a variety of effective oral communication strategies. Students were trained to use these established…

  15. An Analysis of the Effectiveness of Analogy Use in College-Level Biochemistry Textbooks

    Orgill, MaryKay; Bodner, George M.


    Science instructors and textbook authors often use analogies to help their students use information they already understand to develop an understanding of new concepts. This study reports the results of an analysis of the use of analogies in eight biochemistry textbooks, which included textbooks written for one-semester survey biochemistry courses…

  16. Biochemistry Instructors' Views toward Developing and Assessing Visual Literacy in Their Courses

    Linenberger, Kimberly J.; Holme, Thomas A.


    Biochemistry instructors are inundated with various representations from which to choose to depict biochemical phenomena. Because of the immense amount of visual know-how needed to be an expert biochemist in the 21st century, there have been calls for instructors to develop biochemistry students' visual literacy. However, visual literacy has…

  17. Experiences from introduction of peer-to-peer teaching methods in Advanced Biochemistry E2010

    Brodersen, Ditlev; Etzerodt, Michael; Rasmussen, Jan Trige


    During the autumn semester 2010, we experimented with a range of active teaching methods on the course, Advanced Biochemistry, at the Department of Molecular Biology and Genetics.......During the autumn semester 2010, we experimented with a range of active teaching methods on the course, Advanced Biochemistry, at the Department of Molecular Biology and Genetics....

  18. Biochemistry Students' Ideas about How an Enzyme Interacts with a Substrate

    Linenberger, Kimberly J.; Bretz, Stacey Lowery


    Enzyme-substrate interactions are a fundamental concept of biochemistry that is built upon throughout multiple biochemistry courses. Central to understanding enzyme-substrate interactions is specific knowledge of exactly how an enzyme and substrate interact. Within this narrower topic, students must understand the various binding sites on an…

  19. 76 FR 10755 - Establishment of Office of the Chief Scientist; Revision of Delegations of Authority


    ..., Director, Office of the Chief Scientist, United States Department of Agriculture, 1400 Independence Ave... Department) and the Director of the Office of the Chief Scientist with respect to scientific integrity within.... OCS is headed by a Director that reports to the Under Secretary for REE. Pursuant to section 251(c)...

  20. The Chief Diversity Officer: An Examination of CDO Models and Strategies

    Stanley, Christine A.


    Herein, C. A. Stanley comments on R. A. Leon's "Journal of Diversity in Higher Education" article, "The Chief Diversity Officer: An Examination of CDO Models and Strategies" that focuses on the role of the chief diversity officer (CDO) in higher education. Stanley, in her position as Vice President and Associate Provost…

  1. 8 CFR 1003.9 - Office of the Chief Immigration Judge.


    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Office of the Chief Immigration Judge. 1003.9 Section 1003.9 Aliens and Nationality EXECUTIVE OFFICE FOR IMMIGRATION REVIEW, DEPARTMENT OF JUSTICE GENERAL PROVISIONS EXECUTIVE OFFICE FOR IMMIGRATION REVIEW Office of the Chief Immigration...

  2. 21 CFR 5.1105 - Chief Counsel, Food and Drug Administration.


    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Chief Counsel, Food and Drug Administration. 5.1105 Section 5.1105 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ORGANIZATION Organization § 5.1105 Chief Counsel, Food and Drug Administration. The...

  3. 76 FR 53939 - Order of Succession for the Office of the Chief Financial Officer


    ... URBAN DEVELOPMENT Order of Succession for the Office of the Chief Financial Officer AGENCY: Office of the Secretary, HUD. ACTION: Notice of Order of Succession. SUMMARY: In this notice, the Secretary designates the Order of Succession for the Office of the Chief Financial Officer. This Order of...

  4. Perception and Use of Information Sources by Chief Executives in Environmental Scanning.

    Choo, Chun Wei


    Reports on a study of the information sources used in environmental scanning by chief executives of the Canadian telecommunications industry that investigated the relationship between perceived source quality and source use and the chief executives' perception and use of the company library and electronic information sources. (Contains 23…

  5. The Self-Perceived Leadership Styles of Chief State School Officers and Models of Educational Governance

    Wiggins, Lori A.


    This study examined the leadership styles of the chief state school officers of the United States and the District of Columbia. The entire population of 51 chief state school officers was surveyed and a response rate of 60% was obtained. The study examined the relationship between the leadership style, select demographic variables, and the…

  6. Whither life? Conjectures on the future evolution of biochemistry.

    Brewster, Jodi L; Finn, Thomas J; Ramirez, Miguel A; Patrick, Wayne M


    Life has existed on the Earth for approximately four billion years. The sheer depth of evolutionary time, and the diversity of extant species, makes it tempting to assume that all the key biochemical innovations underpinning life have already happened. But we are only a little over halfway through the trajectory of life on our planet. In this Opinion piece, we argue: (i) that sufficient time remains for the evolution of new processes at the heart of metabolic biochemistry and (ii) that synthetic biology is providing predictive insights into the nature of these innovations. By way of example, we focus on engineered solutions to existing inefficiencies in energy generation, and on the complex, synthetic regulatory circuits that are currently being implemented. PMID:27555646

  7. [Foundation and development of biochemistry at the Imperial Kharkov University].

    Kaliman, P A; Chernyshenko, A A


    The article summarizes the biochemical researches carried out at Kharkiv Imperial University from the middle of XIX century up to the cessation of its existence in 1920 as a result of transformation into the Kharkiv Institute of National Education. Scientific activity at the Chair of Medical Chemistry at Medical Department is described in details. Information on professors who led the chair and their researches are represented. Among them a great attention is spared to the Kharkiv works of such famous scientists as A. Danilevsky and V. Gulevich, who made a great contribution to the development of Russian and world biochemistry. There are also some resordes about researches of biological and physiological chemistry carried out at other chairs of Medical Department and Department of Physics and Mathematics of the Kharkiv University. In particular, the article presents the works of well-known plant physiologists and biochemists prof. V. Palladin and V. Zalessky, and the endocrinological researches led by prof. A. Reprev. PMID:10979572

  8. Breast imaging technology: Imaging biochemistry - applications to breast cancer

    The use of magnetic resonance spectroscopy (MRS) to investigate breast tumour biochemistry in vivo is reviewed. To this end, results obtained both from patients in vivo and from tumour extracts and model systems are discussed. An association has been observed between transformation and an increase in phosphomonoesters (PMEs) detected in the 31P MRS spectrum, as well as an increase in choline-containing metabolites detected in the 1H spectrum. A decrease in PME content after treatment is associated with response to treatment as assessed by tumour volume. Experiments in model systems aimed at understanding the underlying biochemical processes are presented, as well as data indicating the usefulness of MRS in monitoring the uptake and metabolism of some chemotherapeutic agents

  9. Mechanisms and biochemistry of methano genesis in biogas production

    Alternative energy sources should be developed to replace fast depleting fossil fuels. The global energy crisis has generated interest in the use of animal waste as a substitute for fossil fuel. The production of biogas which is a mixture of methane, carbon dioxide and traces of other gases, is a biogical process through which wastes are converted to fuels. Through this process, an energy resource that can be stored and used efficiently is produced and an excellent residue that retains the fertiliser value of the original waste is created. This article discusses the biochemistry involved in the production of biogas by anaerobic fermentation of organic waste materials and also the mechanisms of methano genesis involved

  10. Development of a virtual classroom to teach biochemistry

    R.S. Rodrigues


    Full Text Available Knowing  the  difficulties to  teach  some biochemistry concepts  because  of their  dynamic  and  spatial characteristics, computers  have been adopted  to help in these  visualizations.  Pictures, three  dimen- sional structures and animations were built and used to display in classes and distributed to students. Behind  these  specific illustrations, an  informatics  environment has  been  developed  to  support bio- chemistry  teaching.    Based  in  free software,  it fits  in  a single CD  that works  independent of any software installed  on the computer, even the operating  system, and is compatible  with most hardware configurations.This technique is called live-CD. It is based on Linux architecture, which is not only free software but also more flexible to be configured.  After some tests with Linux distributions, Slackware has been chosen because of its easy manipulation and  because it makes the  best use of the hardware  allowing to be installed  in old or limited  equipments. It has been configured to make the best optimization of the computer  and have all software needed for most biochemistry classrooms.It  was installed:   an  Internet browser  compatible  with  a 3D molecule visualization plug-in,  text editor,  presentation editor,  picture  editor  and  some didactic  material  specific for biochemistry.  The interface was configured for people with no experience in the Linux environment.The  system  can  also work in an  intranet, where  a computer  would  be operated  by the  teacher and it would have some special control configurations  as: web site access control, power control of the others  machines  and  even an option  that would bring  the  desktop  of other  machine  to the  teacher´s what  allows him to make a straight orientation for a student from his screen.This new system,  which is a common platform  for other

  11. The origin of pre-neoplastic metaplasia in the stomach: Chief cells emerge from the Mist

    The digestive-enzyme secreting, gastric epithelial chief (zymogenic) cell is remarkable and underappreciated. Here, we discuss how all available evidence suggests that mature chief cells in the adult, mammalian stomach are postmitotic, slowly turning over cells that arise via a relatively long-lived progenitor, the mucous neck cell, The differentiation of chief cells from neck cells does not involve cell division, and the neck cell has its own distinct pattern of gene expression and putative physiological function. Thus, the ontogeny of the normal chief cell lineage exemplifies transdifferentiation. Furthermore, under pathophysiogical loss of acid-secreting parietal cell, the chief cell lineage can itself trasndifferentiate into a mucous cell metaplasia designated Spasmolytic Polypeptide Expressing Metaplasia (SPEM). Especially in the presence of inflammation, this metaplastic lineage can regain proliferative capacity and, in humans may also further differentiate into intestinal metaplasia. The results indicate that gastric fundic lineages display remarkable plasticity in both physiological ontogeny and pathophysiological pre-neoplastic metaplasia.

  12. [V.N. Karazin Kharkov National University as the foundation of biochemistry in Ukraine].

    Kaliman, P A


    The paper deals with the data on foundation and development of physiological chemistry (biochemistry) as independent science and education subject in the V. N. Karazin Kharkov National University before and after the organization of the Department of Physiological Chemistry. Studying the chemistry of natural compounds, their qualitative and quantitative content and transformations in living organisms both by foreign and home researchers made the basis for the appearance of physiological chemistry as static biochemistry. The improvement of the investigation methods and further discoveries caused the appearing of new branches--dynamic and functional biochemistry. The attention is paid to the fact that biochemistry arised at the Kharkov University as the education subject (A. I. Khodnev) and then developed as independent science due to efforts of A. Ya. Danilevskiy as well as biochemical school created by him. The Kazan' and Kharkov periods of scientific activity of A.Ya. Danilevskiy are described. The leading role of A. Ya. Danilevskiy in development of the home school of biochemistry is considered. Important role of A. V. Palladin in the foundation of Kharkov biochemists' school and organization of the Scientific-research Institute of Biochemistry in Kharkov is considered as well. It is stated that the Institute of Biochemistry after its arrival to Kiev and joining the Academy of Sciences became the center of Ukrainian biochemistry. The role of A. V. Nagorny and I. N. Bulankin in further development of biochemistry and foundation of a new scientific branch--age-related physiology and biochemistry--at the Kharkov University after its re-organization is discussed. PMID:18030743

  13. Students’ Blogs as a Tool for Learning Clinical Biochemistry

    E. Cubas


    Full Text Available n the past decade, there has been an exponential growth of blogs on biomedical subjects with reliable contents. The potential use of this media as a learning tool has been recently tried in a medical residence at Harvard University, where students had to produce blogs as part of their duties. At Brasília University, a similar experience was tested with freshmen medical and nutrition students taking Basic Biochemistry (BB with the goal of producing blogs on clinical biochemistry (CB topics. In the last 4 teaching-semesters, students' acceptance (n=267 students regarding BB-blogs was evaluated through 6-point Likert questionnaires. 84% of them agreed that the preparation of their blogs was enjoyable and positive for their academic formation (they marked 4 to 6 in the questionnaire. 57% of students (those marking 5-6 believed that the elaboration of blogs boosted their interest for BB/CB. For 56% of students (those marking 5-6, the blogs motivated them to look for extra-class articles on CB. Only 13% of students (those marking 1-3 did not agree that these blogs are relevant learning tools. 38 out of 58 students’ BB-blogs scored 9.0 or above, only 3 scored below 7.9 (out of 10. These results suggest that student blogs have potential to be effective in stimulating CB learning.

  14. Feasibility of an innovative third-year chief resident system: an internal medicine residency leadership study

    Victor O. Kolade


    Full Text Available Introduction: The role of the internal medicine chief resident includes various administrative, academic, social, and educational responsibilities, fulfillment of which prepares residents for further leadership tasks. However, the chief resident position has historically only been held by a few residents. As fourth-year chief residents are becoming less common, we considered a new model for rotating third-year residents as the chief resident. Methods: Online surveys were given to all 29 internal medicine residents in a single university-based program after implementation of a leadership curriculum and specific job description for the third-year chief resident. Chief residents evaluated themselves on various aspects of leadership. Participation was voluntary. Descriptive statistics were generated using SPSS version 21. Results: Thirteen junior (first- or second-year resident responses reported that the chief residents elicited input from others (mean rating 6.8, were committed to the team (6.8, resolved conflict (6.7, ensured efficiency, organization and productivity of the team (6.7, participated actively (7.0, and managed resources (6.6. Responses from senior residents averaged 1 point higher for each item; this pattern repeated itself in teaching evaluations. Chief resident self-evaluators were more comfortable running a morning report (8.4 than with being chief resident (5.8. Conclusion: The feasibility of preparing internal medicine residents for leadership roles through a rotating PGY-3 (postgraduate year chief residency curriculum was explored at a small internal medicine residency, and we suggest extending the study to include other programs.

  15. Chance and Necessity in Biochemistry: Implications for the Search for Extraterrestrial Biomarkers in Earth-like Environments

    Davila, Alfonso F.; McKay, Christopher P.


    In this paper, we examine a restricted subset of the question of possible alien biochemistries. That is, we look into how different life might be if it emerged in environments similar to that required for life on Earth. We advocate a principle of chance and necessity in biochemistry. According to this principle, biochemistry is in some fundamental way the sum of two processes: there is an aspect of biochemistry that is an endowment from prebiotic processes, which represents the necessity, plu...

  16. EDITORIAL: Greetings from the new Editor-in-Chief

    Garcia, Ephrahim


    I am Professor Ephrahim Garcia, an Associate Professor at Sibley School of Mechanical and Aerospace Engineering at Cornell University in Ithaca, New York. I have been at Cornell University since 2002, spent four years as a Program Manager at the Defense Advanced Research Project Agency from 1998-2002, and before that seven years at the Department of Mechanical Engineering at Vanderbilt University in Nashville, Tennessee. I have served on the Editorial Advisory Board of Smart Materials and Structures (SMS) for the last six years. It is a humbling thing to be asked to take up the post of Editor-in-Chief in a field with so many talented researchers. I would like to say a heartfelt thanks to the members of the Editorial Board and IOP Publishing for their confidence in me. Most importantly, I would like to thank Professor Vijay Varadan of the University of Arkansas and Professor Richard Claus of Virginia Polytechnic Institute and State University for their efforts in launching the journal 16 years ago. They have been stewards, promoters and, especially Vijay, key to the operation and function of SMS for all these years, and our research community is indebted to them. Professors Varadan and Claus have dedicated their careers to the area of smart materials and structures and we are very grateful for their leadership, mentoring and contribution. SMS is a thriving journal offering papers on all technical areas concerned with smart materials, systems and structures from the micro- and nanoscale to the macroscale. The journal is undergoing some major changes, including the recent transferal of papers to IOP Publishing's peer-review management system. With this new system authors can expect fast publication times of around 4 or 5 months from submission, and excellent author service. In this world of ever changing technology, the Editorial Board and I aim to reduce the time to publication for researchers in this exciting area of science and engineering. I am in the process of

  17. The successful Chief Executive Officer understands quality assurance

    The successful Chief Executive Officer (CEO) will have recognized the benefits of, and have implemented, a total quality assurance program. The quality assurance program will be adequately defined in policies and procedures such that managers and supervisors of each organizational element understand their primary and supporting roles in carrying out an effective quality assurance program. The traditional practice of having all quality assurance activities reside in a quality assurance organization will have been cast aside. Instead, the quality assurance activities necessary to achieve and assure the quality of the desired end product will have been defined and assigned to responsible organization elements. The quality assurance organization's primary role will be to define the total quality assurance program, insure that the achieving and assuring functions are assigned in policies and procedures, conduct training necessary to have management and supervisors understand the total quality assurance program, measure the effectiveness of the program and feedback measurement data for improvements in the program. The successful CEO will have implemented a quality assurance program that provides for a graded approach for application of the program based upon the importance of the intended use of the product or service. The successful CEO will rely heavily on the scheduled progress reports and assessments to measure the pulse of his organization's successes and improvement needs. This paper will describe suggested approaches for the Quality Assurance Manager to implement a quality assurance program which results in his corporation's CEO being a supporter of and a driving force in the implementation of the quality assurance program

  18. The Big Data Revolution: Opportunities for Chief Nurse Executives.

    Remus, Sally


    Informatics competency adoption is a recognized issue across nursing roles in digital health practice settings. Further, it has been suggested that the health system's inability to reap the promised benefits of electronic health/patient records is, in part, a manifestation of inadequate development of informatics competency by chief nurse executives (CNEs) and other clinicians (Amendola 2008; Simpson 2013). This paper will focus on CNE informatics competency and nursing knowledge development as it pertains to the Big Data revolution. With the paper's aim of showing how CNEs armed with informatics competency can harness the full potential of Big Data offering new opportunities for nursing knowledge development in their clinical transformation roles as eHealth project sponsors. It is proposed that informatics-savvy CNEs are the new transformational leaders of the digital age who will have the advantage to successfully advocate for nurses in leading 21st-century health systems. Also, transformational CNEs armed with informatics competency will position nurses and the nursing profession to achieve its future vision, where nurses are perceived by patients and professionals alike as knowledge workers, providing the leadership essential for safe, quality care and demonstrating nursing's unique contributions to fiscal health through clinically relevant, evidence-based practices (McBride 2005b). PMID:27122086

  19. Chief nursing officer executive development: a crisis or a challenge?

    Frederickson, Keville; Nickitas, Donna


    The roles and responsibilities of nurses are expanding, as they become more involved in administration and leadership within their field. Nurses are taking on executive positions, which have become a crucial part of hospital organizations. With this expansion, an executive development program is necessary to provide nurses with the knowledge and competencies that these executive positions require. Their focus must evolve from singular bedside practice to the greater scope of health care administration. Leadership skills are extremely important, in addition to interpersonal, management, mentoring, and interprofessional skills. A number of nursing associations have worked to develop a set of curricula for nurse executive education, but a consistent and specific set of academic requirements has yet to be agreed upon. With the importance of the chief nursing officer's (CNO) role in the function of a hospital and the requirement of the knowledge of the changing health care system in the United States, it is essential that nurses are provided with proper education and training that will help them become successful nurse executives. Some suggestions include a dual MSN/MBA degree, a PhD in nursing, continuing education institutes, and mentoring programs. However, research must be done to clarify the best way to prepare CNOs for their roles. PMID:21900820

  20. EDITORIAL: A word from the new Editor-in-Chief A word from the new Editor-in-Chief

    Mostowski, Jan


    TIn the autumn of 2010 I became the Editor-in Chief of European Journal of Physics (EJP). EJP is a place for teachers, instructors and professors to exchange their views on teaching physics at university level and share their experience. It is general opinion that no good research is possible without connection with good, high-quality teaching, at the university level in particular. Therefore excellence in physics teaching is important to the physics community. European Journal of Physics is proud of its contribution to achieving this goal. As Editor-in-Chief, I will continue to work to this general objective of the journal. We will publish articles on specific topics in physics, stressing originality of presentation and suitability for use in students'laboratories, lectures and physics teaching in general. We will also publish more pedagogical papers presenting the achievements of particular teaching methods. In addition, we will continue to publish special sections on particular areas of physics, as well as the annual special section on physics competitions. European Journal of Physics is in good shape. Due to the work of the previous editors and the publisher, the readership is high and growing steadily, and many excellent papers are being submitted and published. I hope that this positive trend for the journal will continue, and I will do my best to keep to this high standard. A few words about myself. I work in the Institute of Physics in Warsaw, Poland. My main research interests are in theoretical quantum optics and I have published about 80 research papers on this topic. For many years I was involved in teaching physics at university and in high school. I am a co-author of a textbook on physics for high-school students and of a problem book in quantum mechanics. For the last ten years, I have been involved in the International Physics Olympiad and over the last few years I have been a member of the Editorial Board of European Journal of Physics.

  1. Molecular Biology, Biochemistry and Cellular Physiology of Cysteine Metabolism in Arabidopsis thaliana

    Hell, Rüdiger; Wirtz, Markus


    Cysteine is one of the most versatile molecules in biology, taking over such different functions as catalysis, structure, regulation and electron transport during evolution. Research on Arabidopsis has contributed decisively to the understanding of cysteine synthesis and its role in the assimilatory pathways of S, N and C in plants. The multimeric cysteine synthase complex is present in the cytosol, plastids and mitochondria and forms the centre of a unique metabolic sensing and signaling system. Its association is reversible, rendering the first enzyme of cysteine synthesis active and the second one inactive, and vice-versa. Complex formation is triggered by the reaction intermediates of cysteine synthesis in response to supply and demand and gives rise to regulation of genes of sulfur metabolism to adjust cellular sulfur homeostasis. Combinations of biochemistry, forward and reverse genetics, structural- and cell-biology approaches using Arabidopsis have revealed new enzyme functions and the unique pattern of spatial distribution of cysteine metabolism in plant cells. These findings place the synthesis of cysteine in the centre of the network of primary metabolism. PMID:22303278

  2. The use of software in Biochemistry teaching classes

    M.B. Büttenbender


    Full Text Available INTRODUCTION: The rising of new technologies meant  to improve education could be considered a high advance to pedagogic methodologies. Software is defined as computer programs and may be considered educative when they present a methodology which assists and contextualizes the teaching-learning process. Specifically regarding Biochemistry, a knowledge area which explains physiological and pathological phenomena that occur in human beings, applying the use of software would turn out an easy way to observe suchphenomena. MATERIAL AND METHODS: In order to carry out this work, two free software designed to be used in Biochemistry area and developed at Universidade Estadual de Campinas (“Síntese Proteica” (Protein Synthesisand “A cinética da reação enzimática” (Kinetics of enzymatic reaction, were compared. Interface, how to work contents, advantages and disadvantages in the use of such kind of technology inside classroom were some of the evaluated parameters. DISCUSSION AND RESULTS: Both programs present a fine graphic design, allowing easy command comprehension. At the beginning the objectives of the programs and the contents they hold are presented, showing also a brief introduction to the topic. The programs also  present instruction manuals that explain how the experiments work. They are small basic and simple programs that run easily where they are placed, not needing internet access after their download. “Kinetics of enzymatic reaction” presented more interactive options than the other, and its operation could be considered more intuitive. CONCLUSION: We considered “Kinetics of enzymatic reaction” a better software,cause it allows the student to observe the experiment and perform the calculationsproposed, improving the learning process in a significantly way. The use ofnew technologies inside classrooms should be encouraged as a way to attractthe attention and interest of students, since they are


    J.M. Martins


    Full Text Available The cybernetic spaces simulate the real world with interactive multimedia. This work  has been applied since January, 2007 on the curricular student’s apprenticeship at high school and graduation, in the site “”. It has been developed to provide continuity to the technical-scientific learning of students and professionals, and also to improve their human social relations on the  labour  environment.  It’s comprises a virtual space, destined to communication and collective building of knowledge on the clinical biochemistry.   It’s about an interactive environment which allows the users registered as coordinator professor (professional  or the scientist student (trainee,  unlimited access to  posting contents (classes, texts, presentations, animations, consultations, non-synchronic discussions (on orkut, forums, e-mail and synchronic discussions (on chats, videoconferences. After a few live tutorials  about new  input in this environment, and the use of the new learning tool,  the collective building of knowledge on cyberspace begins. As a trainee’s program task, the scientist student would have to build a space of his own, under guidance and supervision of the coordinator teachers.  The cyberspace efficiency was evaluated from reports collected in February, 2008: the adherence to this  work was satisfactory, regarding this period, with 68 registered users, 870 accesses and 52 contents available on the several sections of the virtual laboratory. Our work is still being applied, and new adhesions are  happening everyday. We intend to amplify this cyber environment in order to make it a  permanent  continued education site on the health area.  From interest contracts and common knowledge,  the technological interfaces constitute an interaction, in which everyone is a potential author.  Keywords: Cyberspace, online biochemistry education, continued education.

  4. Oxidative Damage and Suppression: an Experimental Approach to Teaching Biochemistry

    Isa G. J. de Avellar


    Full Text Available Experimental Biochemistry is a challenging and worthy didactical  task:  a vast field with many different techniques.   Radical mediated biooxidative processes, implied in aging and accompanying various pathologies,  have an enormous  appeal  to public in general and particularly to students in the science field.   The  Fenton  reaction,   first  reported by  the 22-year  old Cambridge  chemistry  undergraduate Henry J. H. Fenton  (Chemical  news vol. 33 page 190, 1876, is a useful in vitro system for generating hydroxyl radicals generally implied in biooxidation.  When coupled with the 2-deoxyribose (DR- thiobarbituric acid (TBA  method,  provides  a most  resourceful  tool for studying  oxidative  processes that may  provide  insights  to  in  vivo  processes.    In  this  communication  a  classical  experiment of quantification of thiobarbituric reactive  substances  (TBARS resulting  from breakage  of DR (5 mM in aqueous buffered media (5mM, pH 7.2 by 0,100 mM H2O2 and ferrous ion (up to 0,150 mM is the base for the demonstration of oxidative damage suppressive ability of known hydroxyl radical quenchers as ethanol,  dimethylsulfoxide (DMSO  and  thiourea (1mM  each.   The  results  of the  experiments, developed  to  be worked  in experimental classes for senior  undergraduate biochemistry students of biomedical  sciences, show a very mild but  consistent  suppressive  capacity  for ethanol  (reduction in2 percent  of TBARS  measured  at  0,150 mM ferrous ion concentration.  Thiourea  and  DMSO show very similar  suppressive  abilities:  reduction  in 19 and  18 percent  in measured  TBARS,  respectively (at  0,150 mM ferrous ion.


    W. B. Maia


    Full Text Available Constructivism employs  models  that include  epistemological knowledge  and  strategies to  stimulate and motivate students so that they need to construct their own understanding of any subjetc  concept. Under  this  process,  the  primary  role of teaching  is not  to lecture,  explain,  or otherwise  attempt to´transferk´nowledge, but to create.  This principle was used in the Biochemistry Master Science Program of the  Universidade  Federal  de Pernambuco.  The  model applied  was divided  into  four phases:  (1 acquaintance of the student previous knowledge (using a pre-test; (2 presentation of the knowledge using a Science Teaching  CD-Rom;  (3 submission  of the  learned  content by the  student to teacher critical  analyis  and  (4  application of Interactionism (teacher/student/contents.   Each  phase  was individually  evaluated.  In the  first phase,  the  average  of correct  answers  of the  group  (13 students was 64%, whereas  the  second and  third  phases  presented  61% and  53%, respectively.   These  results reveal  a great  congnitive  unbalance  into  the  group.   They  also showed that the  previous  ideas and hypothesis  of the  students were in conflict  with  the  scientific  concepts.   After  teacher intervention (phase  four  the  group  presented  an increase  in the knowledge (86% of correct  answers.   Based  on these  results  one can conclude  that this  four-phase  model applied  and  based  on Constructivism  for acquiring  knowledge can be useful in Biochemistry  teaching.

  6. EDITORIAL: Farewell from the outgoing Editor-in-Chief Farewell from the outgoing Editor-in-Chief

    Molenkamp, Laurens W.


    At the end of 2011 I will retire as Editor-in-Chief of Semiconductor Science and Technology, and I am very pleased to announce that the job will be taken over by Professor Kornelius Nielsch. In the ten years I have held this position, I have seen many new topics entering the journal: spintronics, organic semiconductors, and Dirac fermion physics, to name just a few. The journal has also witnessed a strong internationalization of the authorship, with an especially strong increase in contributions from the Far East—a growth that is likely to continue in the coming years. I am certain that Kornelius will do an excellent job in guiding the journal through the developments of the coming decade. I would like to thank the publishing team of SST, or rather the three consecutive teams I witnessed during my tenure at the journal, for the help and support they have given me. The people at IOP Publishing are doing a great job in running the journal, and have made it possible to considerably reduce the time to publication for our submissions. I much enjoyed the collaboration with the other members of the Editorial Board; our annual meetings have always been a source of inspiration. Last, but certainly not least, I would like to thank you, the scientific community, authors, referees and readers, for your continuing support of the journal.

  7. EDITORIAL: Greetings from the new Editor-in-Chief

    Bhattacharya, P.


    On 1 January, 2004, I assumed the position of Editor-in-Chief of Journal of Physics D: Applied Physics. I will start by saying that I will do my best to justify the confidence of the journal management and publishing staff in my abilities. I was fortunate to have been able to work, as an Editorial Board member, with my predecessor, the previous Editor-in-Chief, Professor Allister Ferguson. Allister has provided a high degree of intellectual stewardship for the journal in the last five years. He has made the job appear a worthy challenge for me. I therefore take this opportunity to thank Allister on behalf of the Editorial Board and publishing staff of the journal. Several other factors contributed to my decision to accept this position. The first is the group of people who actually go about the business of publishing. The Senior Publisher, Nicola Gulley (and her predecessor Sophy Le Masurier); the Managing Editor, Jill Membrey; the Publishing Administrators, Nina Blakesley and Sarah Towell; the Production Editor, Katie Gerrard and their office staff form an amazing group and have managed to make the operation of the journal incredibly efficient. An index of this is the speed with which incoming manuscripts are processed. The average time between the receipt of a manuscript and its web publication, if accepted, is 130 days. This is three to five times shorter than for most other journals. A factor that contributes to this success is a responsive pool of referees that the publishing staff have as a valuable resource. Ultimately, the standard bearers of any journal are the referees. Therefore, a grateful `thank you' is due from all of us at J. Phys. D to all our referees, who diligently perform this honourable task. The Associate Editors of the journal, Professors Lawler, Margaritondo and O'Grady, also provide immense scientific leadership. They help in defining new directions for the journal and in the publishing process. Last, but not least, a remarkable asset of

  8. EDITORIAL: Message from the new Editor-in-Chief

    Dendy, R.


    On 1 January 2005 I become Editor-in-Chief of Plasma Physics and Controlled Fusion. I look forward to assisting contributors, referees and the Board in maintaining the high standards of this international journal, whose bibliometric impact factor has consistently matched or exceeded that of other journals in the field. The robust, good health of Plasma Physics and Controlled Fusion reflects that of its user communities. With a decision to proceed to the construction of ITER apparently imminent, magnetic confinement fusion research is preparing to take a major step forwards. A new generation of laser-plasma interaction facilities for inertial fusion research is also rising at key sites around the world. Technical progress in our field is underpinned by scientific excellence, and the publication of results in Plasma Physics and Controlled Fusion will, I hope, continue to play its part. The journal will continue to offer the benefits of refereeing by two experts, combined with the rapid turnaround achieved by the highly efficient editorial office at the Institute of Physics Publishing in Bristol. Looking elsewhere, there may be opportunities for gentle incremental broadening of the scientific scope of the journal, in the medium term. One looks in particular to those branches of plasma physics that, in recent years, have become more strongly represented in the series of conferences organized by the Plasma Physics Division of the European Physical Society. The recent special issue of Plasma Physics and Controlled Fusion (Plasma Phys. Control. Fusion 46 (2004) B1--592) provides an indication. Finally, it is a pleasure to thank my predecessor, Professor Ian Hutchinson of the Massachusetts Institute of Technology, for handing on his role with the journal in such promising condition.

  9. The Chief Resident Role in Emergency Medicine Residency Programs

    Hafner, John W. Jr., MD, MPH


    Full Text Available Study Objectives: Although other specialties have examined the role of the chief resident (CR, the role and training of the emergency medicine (EM CR has largely been undefined.Methods: A survey was mailed to all EM CRs and their respective program directors (PD in 124 EM residency programs. The survey consisted of questions defining demographics, duties of the typical CR, and opinions regarding the level of support and training received. Multiple choice, Likert scale (1 strong agreement, 5 strong disagreement and short-answer responses were used. We analyzed associations between CR and PD responses using Chi-square, Student’s T and Mann-Whitney U tests.Results: Seventy-six percent of CRs and 65% of PDs responded and were similar except for age (31 vs. 42 years; p<0.001. CR respondents were most often male, in year 3 of training and held the position for 12 months. CRs and PDs agreed that the assigned level of responsibility is appropriate (2.63 vs. 2.73, p=0.15; but CRs underestimate their influence in the residency program (1.94 vs. 2.34, p=0.002 and the emergency department (2.61 vs. 3.03, p=0.002. The majority of CRs (70% and PDs (77% report participating in an extramural training program, and those CRs who participated in training felt more prepared for their job duties (2.26 vs. 2.73; p=0.03.Conclusion: EM CRs feel they have appropriate job responsibility but believe they are less influential in program and department administration than PD respondents. Extramural training programs for incoming CRs are widely used and felt to be helpful. [West J Emerg Med. 2010; 11(2:120-125.

  10. Visual Literacy and Biochemistry Learning: The role of external representations

    V.J.S.V. Santos


    Full Text Available Visual Literacy can bedefined as people’s ability to understand, use, think, learn and express themselves through external representations (ER in a given subject. This research aims to investigate the development of abilities of ERs reading and interpretation by students from a Biochemistry graduate course of theFederal University of São João Del-Rei. In this way, Visual Literacy level was  assessed using a questionnaire validatedin a previous educational research. This diagnosis questionnaire was elaborated according to six visual abilitiesidentified as essential for the study of the metabolic pathways. The initial statistical analysis of data collectedin this study was carried out using ANOVA method. Results obtained showed that the questionnaire used is adequate for the research and indicated that the level of Visual Literacy related to the metabolic processes increased significantly with the progress of the students in the graduation course. There was also an indication of a possible interference in the student’s performancedetermined by the cutoff punctuation in the university selection process.