Implications of the Central America-Dominican Republic-Free Trade Agreement for the nutrition transition in Central America.

Science.gov (United States)

Hawkes, Corinna; Thow, Anne Marie

2008-11-01

To identify potential impacts of the Central America-Dominican Republic-Free Trade Agreement (CAFTA-DR) on food consumption patterns associated with the nutrition transition, obesity, and diet-related chronic diseases. Examination of CAFTA-DR agreement to identify measures that have the potential to affect food availability and retail prices. CAFTA-DR includes agreements on tariffs, tariff-rate quotas (TRQs), and sanitary and phytosanitary regulations with direct implications for the availability and prices of various foods. Agreements on investment, services, and intellectual property rights (IPR) are also relevant because they create a business climate more conducive to long-term investment by the transnational food industry. Trade liberalization under CAFTA-DR is likely to increase availability and lower relative prices of two food groups associated with the nutrition transition: meat and processed foods. These outcomes are expected to occur as the direct result of increased imports from the United States and increased production by U.S. companies based in Central America, and the indirect result of increased domestic meat production (due to increased availability of cheaper animal feed) and increased production of processed foods by domestic companies (due to a more competitive market environment). CAFTA-DR is likely to further the nutrition transition in Central America by increasing the consumption of meat; highly processed foods; and new, non-traditional foods. The public health community should be more aware of the implications of trade agreements for dietary health. Governments and related stakeholders should assess the coherence between changes fostered by specific trade agreements with national policies on diet and nutrition.

Social determinants of workers' health in Central America.

Science.gov (United States)

Aragón, Aurora; Partanen, Timo; Felknor, Sarah; Corriols, Marianela

2011-01-01

This communication summarizes the available data on work-related determinants of health in Central America. The Central American working population is young and moving from agriculture toward industry and services. Ethnicity, gender, migration, subemployment and precarious work, informality, rural conditions, low-level educational, poverty, ubiquitous worksite health hazards, insufficient occupational health services, low labor inspection density, and weak unions define the constellation of social determinants of workers' health in Central America. Data are, however, scanty both for hazards and work-related illnesses and injuries. Governments and industries have the responsibility of opening decent work opportunities, especially for those facing multiple inequalities in social determinants of health. A first step would be the ratification and implementation of the ILO Convention (187) on occupational safety and health by the seven national governments of the region.

Earth and water resources and hazards in Central America

Science.gov (United States)

Cunningham, Charles G.; Fary, R.W.; Guffanti, Marianne; Laura, Della; Lee, M.P.; Masters, C.D.; Miller, R.L.; Quinones-Marques, Ferdinand; Peebles, R.W.; Reinemund, J.A.; Russ, D.P.

1984-01-01

Long-range economic development in Central America will depend in large part on production of indigenous mineral, energy, and water resources and on mitigation of the disastrous effects of geologic and hydrologic hazards such as landslides, earthquakes, volcanic eruptions, and floods. The region has six world-class metal mines at present as well as additional evidence of widespread mineralization. Systematic investigations using modern mineral exploration techniques should reveal more mineral deposits suitable for development. Widespread evidence of lignite and geothermal resources suggests that intensive studies could identify producible energy sources in most Central American countries. Water supply and water quality vary greatly from country to country. Local problems of ground- and surface-water availability and of contamination create a need for systematic programs to provide better hydrologic data, capital improvements, and management. Disastrous earthquakes have destroyed or severely damaged many cities in Central America. Volcanic eruptions, landslides, mudflows, and floods have devastated most of the Pacific side of Central America at one time or another. A regional approach to earthquake, volcano, and flood-risk analysis and monitoring, using modern technology and concepts, would provide the facilities and means for acquiring knowledge necessary to reduce future losses. All Central American countries need to strengthen institutions and programs dealing with earth and water resources and natural hazards. Some of these needs may be satisfied through existing or pending projects and technical and economic assistance from U.S. or other sources. The need for a comprehensive study of the natural resources of Central America and the requirements for their development is evident. The U.S. Caribbean Basin Initiative offers both an excellent opportunity for a regional approach to these pervasive problems and an opportunity for international cooperation.

7 CFR 319.56-25 - Papayas from Central America and Brazil.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Papayas from Central America and Brazil. 319.56-25... § 319.56-25 Papayas from Central America and Brazil. The Solo type of papaya may be imported into the... shipment to the United States in one of the following locations: (1) Brazil: State of Espirito Santo; all...

Harmonization of Legislation against Organized Crime in Central America

Directory of Open Access Journals (Sweden)

Jaime Edwin Martínez Ventura

2014-05-01

Full Text Available With the expansion of organized crime in Central America, the countries in this continental sub-region have enacted a great deal of internal legislation, and have ratified international treaties at the universal, regional and Central American level, particularly after the United Nations Convention against Transnational Organized Crime took effect in 2000.This abundance of laws is very positive, and is an expression of these Central American States’ intent to fulfill their supranational obligations and provide security for their inhabitants. However, it is also negative in that it has led to dispersion, dislocation, discrepancies and inaccuracies regarding the prevailing legal regulations, because national laws have been developed with different concepts, structures, approaches, scope and definitions.Despite these conditions that are adverse to legal harmonization, Central America can move forward with matching its legislation against organized crime. Actually, there already exists an extensive common legal framework in this area, expressed in the fact that most international treaties on Organized Crime have come into force at the universal, regional and subregional levels, ratified by all or most countriesPolitical will is the common denominator that should mediate all efforts of harmonization and alignment of legislation in Central America; it is essential for proposing steps that are based on a common strategy or program.DOI: http://dx.doi.org/10.5377/rpsp.v1i2.1359

Biomass energy in Central America

Energy Technology Data Exchange (ETDEWEB)

Blanco, J M [Biomass Users` Network, Regional Office for Central America and the Caribbean, San Jose (Costa Rica)

1995-12-01

The objective of this paper is to introduce the concept of biomass to energy issues and opportunities in Central America. In this region, made up of seven countries (Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama), the biomass sector has the potential to play a crucial role in alleviating the environmental and development predicaments faced by all economies of the region. This paper assesses the available biomass resources at the regional and country levels and gives an overview of the current utilization of biomass fuels. It also describes the overall context in which the biomass-to-energy initiatives are immersed. At the regional level, biomass energy consumption accounts for more than 50% of total energy consumption. In regard to the utilization of biomass for energy purposes, it is clear that Central America faces a critical juncture at two levels, both mainly in rural areas: in the productive sector and at the household level. The absence of sustainable development policies and practices has jeopardized the availability of biomass fuels, particularly wood. Firewood is an important source of energy for rural industries such as coffee processing, which is one of the largest productive activities in the region. This paper comments on some of the most successful technological innovations already in place in the region, for instance, the rapid development of co-generation projects by the sugar cane industry, especially in El Salvador and Guatemala, the substitution of coffee husks for firewood in coffee processing plants in Costa Rica and El Salvador and the sustainable use of pine forests for co-generation in Honduras. Only one out of every two inhabitants in Central America now has access to electricity from the public grid. Biomass fuels, mainly firewood but also, to a lesser extent, other crop residues such as corn stalks, are the main source of energy for cooking and heating by most of the population. (It is foreseen that by the end

Biomass energy in Central America

International Nuclear Information System (INIS)

Blanco, J.M.

1995-01-01

The objective of this paper is to introduce the concept of biomass to energy issues and opportunities in Central America. In this region, made up of seven countries (Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama), the biomass sector has the potential to play a crucial role in alleviating the environmental and development predicaments faced by all economies of the region. This paper assesses the available biomass resources at the regional and country levels and gives an overview of the current utilization of biomass fuels. It also describes the overall context in which the biomass-to-energy initiatives are immersed. At the regional level, biomass energy consumption accounts for more than 50% of total energy consumption. In regard to the utilization of biomass for energy purposes, it is clear that Central America faces a critical juncture at two levels, both mainly in rural areas: in the productive sector and at the household level. The absence of sustainable development policies and practices has jeopardized the availability of biomass fuels, particularly wood. Firewood is an important source of energy for rural industries such as coffee processing, which is one of the largest productive activities in the region. This paper comments on some of the most successful technological innovations already in place in the region, for instance, the rapid development of co-generation projects by the sugar cane industry, especially in El Salvador and Guatemala, the substitution of coffee husks for firewood in coffee processing plants in Costa Rica and El Salvador and the sustainable use of pine forests for co-generation in Honduras. Only one out of every two inhabitants in Central America now has access to electricity from the public grid. Biomass fuels, mainly firewood but also, to a lesser extent, other crop residues such as corn stalks, are the main source of energy for cooking and heating by most of the population. (It is foreseen that by the end

Federacion de Universidades Privadas de America Central y Panama: Boletin Estadistico (Federation of Private Universities of Central America and Panama: Statistical Bulletin).

Science.gov (United States)

Serrano, Jorge A.

This statistical bulletin provides details on the universities belonging to the Federation of Private Universities of Central America and Panama (FUPAC): Central American University, Rafael Landivar University, Saint John's College, University of Santa Maria La Antigua, Jose Simeon Canas University, Doctor Mariano Galvez University, and the…

Remittances in Central America: Whose Money is it Anyway?

Directory of Open Access Journals (Sweden)

Jose Luis Rocha

2015-08-01

Full Text Available In opposition to optimistic visions that present remittances as an opportunity for developing countries, this paper shows they are part and parcel of a process of economic imperialism, whereby their use and final destinations are strictly conditioned. In order to go beyond a conception of remittances as epiphenomenon, and in order to trace the role they play, this paper focuses on the transnational strategies of capital. It finds that remittances enable an increase in foreign investment and import production by facilitating the rise of a new class of consumers in Central America. Remittances create and feed a purchasing power that would not exist in their absence. Factories, fast food restaurants, communications companies, banks, travel agencies, and supermarkets are opening new branches throughout Central America in order to benefit from transnational savings that would otherwise be used differently. In this way, remittances are conditioned and co-opted by transnational capital’s strategies to sustain an ever growing market, with Central America more generally – and once again – potentially at risk of becoming characterized by enclave economies and chronic commercial deficits. The remittance-based economic model furthermore cannot be sustainable in the long run unless Central American countries keep exporting workers ad infinitum, something that is obviously not possible.

A GPS Modeling Study of Earthquakes and Deformation in Northern Central America and along the Middle America Trench: 1999 to 2017

Science.gov (United States)

Ellis, Andria P.

Northern Central America is a tectonically complicated region prone to hazardous earthquakes due to the confluence of the Motagua-Polochic fault zone with the Middle America trench and strike-slip faults in the Central America volcanic arc. These three major fault zones converge at the western end of the Caribbean plate where the Cocos plate subducts under the North America and Caribbean plates. Literature from the 1970s and 1980s focused on whether a discrete North America-Caribbean-Cocos plate triple junction existed, and how the relative motions of the upper North America and Caribbean plates were accommodated. The discovery of a fourth major crustal block, the Central America forearc sliver, from seismic and geodetic observations made a three-plate triple junction geometrically impossible and introduced a new set of questions related to how deformation of the upper plate accommodates relative movements between the Caribbean plate, North America plate, and Central America forearc sliver where they intersect in the upper plate. My dissertation uses GPS and numerical modeling to measure and quantify earthquake transients and crustal deformation related to fault interactions in northern Central America and consists of three related chapters. The first chapter of my dissertation is a geodetic study of a M w = 7.4 subduction zone earthquake that occurred in 2012 offshore from our Guatemala GPS (Global Positioning System) network. For this study, I inverted coseismic site offsets and postseismic amplitudes to determine best-fitting coseismic and afterslip rupture distributions on the Middle America trench. I also determined the maximum likely viscoelastic deformation for the earthquake to test whether the transient postseismic deformation was dominated by fault afterslip or viscoelastic flow. This work was published in Geophysical Journal International in January 2015. The second chapter of my dissertation derives a new 200+ site GPS velocity field for northern

COELIAC DISEASE IN CENTRAL AND SOUTH AMERICA: time for a concerted approach to its epidemiology

Directory of Open Access Journals (Sweden)

Affifa FARRUKH

2015-06-01

Full Text Available Central and South America offer an opportunity to resolve some of the current controversies that surround the epidemiology of celiac disease. Through a concerted action which brings together clinicians, researchers and patients there is an opportunity to establish robust data sets which will allow detailed analysis of environmental and genetic factors. In this review available data from the continent together with data from Spain and Italy are drawn together to give a current picture in the hope that it will stimulate further research.

(Human Security in Central America: A Return to the Past?

Directory of Open Access Journals (Sweden)

Jordi Urgell García

2007-02-01

Full Text Available After having become one of the principal scenarios of the Cold War, the pacification and democratisation of Central America in the 1990s were forged under the protection of the Esquipulas Process and the birth of the concept of human security. The resulting model of security was founded on the Framework Treaty on Democratic Security, which incorporated some of the basic postulates of human security and became one of its first institutional implementations. Nevertheless, the performance of this model has been eclipsed and questioned by the evolution of events in Central America (such as the impact of 9-11 on security agendas or the emergence of new forms of violence in the region, which open the door to a new security instrument (the Rapid Reaction Force, generate fears about an eventual regression of Central America in the area of security and raise doubts about the habitual assumptions of human security.

Economic opportunities and challenges posed by China for Mexico and Central America

OpenAIRE

Dussel Peters, Enrique

2005-01-01

"This study offers a basis for understanding China's performance from a Latin American perspective, and stressing the massive economic opportunities and challenges, and particularly for Central America and Mexico. Moreover, the document assesses in detail the macroeconomic, trade and employment policy and institutional changes in China and its potential effects in Central America and Mexico. These effects are analyzed in the Chinese, Central American, Mexican and US market in general, but als...

Volcanic hazards in Central America

Science.gov (United States)

Rose, William I.; Bluth, Gregg J.S.; Carr, Michael J.; Ewert, John W.; Patino, Lina C.; Vallance, James W.

2006-01-01

This volume is a sampling of current scientific work about volcanoes in Central America with specific application to hazards. The papers reflect a variety of international and interdisciplinary collaborations and employ new methods. The book will be of interest to a broad cross section of scientists, especially volcanologists. The volume also will interest students who aspire to work in the field of volcano hazards mitigation or who may want to work in one of Earth’s most volcanically active areas.

Central America's shrinking forests.

Science.gov (United States)

1992-01-01

This news brief reports that 66% of deforestation in Central America has happened in the past 40 years, based on World Conservation Union (WCU) data. Deforestation is expected to continue. The population of Central America and Mexico grew by 28% between 1977 and 1987. Growth is decreasing but remains high at 2.5% in all countries of the region except Panama. 29 million was the regional population in 1990; the projection is for 63 million by 2025. Population is migrating to urban centers. Forests declined by 13% and croplands increased from 4% to 13% of total land area and pasture land from 2% to 37%. There was an increase in unproductive land from 145 to 24%, i.e., 50% of El Salvador's land had soil degradation as does 30% of Guatemala's. In addition to deforestation and soil degradation, there has been soil erosion leading to sedimentation buildup near dam sites and in rivers, which diminishes hydroelectric power capability. Silting also affects groundwater resources, which impact on a safe drinking water supply. Population growth results in increased demand for fuelwood, urban land, and agricultural land. New techniques practiced widely are needed in order to meet the region's needs or demands. Slowing population growth buys time for adjusting to the necessary changes needed for sustaining the region's population. WCU urges conservation organizations to raise awareness about the role population plays in environmental degradation, and to support efforts to reduce birth rates. Women's status needs to be improved through income-generating projects, for instance, and cooperation is needed between conservation groups and organizations involved with improving maternal and child health.

The State of Federal Research Funding in Genetics as Reflected by Members of the Genetics Society of America.

Science.gov (United States)

Rine, Jasper; Fagen, Adam P

2015-08-01

Scientific progress runs on the intellect, curiosity, and passion of its practitioners fueled by the research dollars of its sponsors. The concern over research funding in biology in general and genetics in particular led us to survey the membership of the Genetics Society of America for information about the federal support of genetics at the level of individual principal investigators. The results paint a mosaic of circumstances-some good, others not so good-that describes some of our present challenges with sufficient detail to suggest useful steps that could address the challenges. Copyright © 2015 by the Genetics Society of America.

Genetic characterization of Neotropical Jabiru Storks: Insights for conservation

Science.gov (United States)

Lopes, I.F.; Haig, S.M.; Lama, S.N.D.

2010-01-01

Jabiru Stork (Jabiru mycteria is listed under Appendix I of CITES and considered threatened in Central America. The first population genetic analysis of Jabiru Storks was carried out using mitochondrial DNA (mtDNA) control region sequences (520 bp) and five heterologous microsatellite loci. Samples were collected from the field (N = 49) and museum skins (N = 22) in Central (mainly Belize, Nicaragua and Costa Rica) and South America (Colombia, Venezuela, Peru and Brazil). A decline of mtDNA diversity was observed in comparisons between past (N = 20) and present (N = 40) samples collected in Central America and northern South America. Similar levels of microsatellite loci diversity were observed among contemporary samples. Lower levels of mtDNA variability were observed in samples from Central America and northern South America when compared to the Brazilian Pantanal region. Significant levels of genetic differentiation were found between contemporary locations sampled, whereas non-significant results were observed for historic samples. The non-geographic association of haplotypes observed at the cladograms and the recent divergence times estimated between locations are indicative of an evolutionary history of a large population size with limited population structure. Reconnection of populations via increased gene flow, particularly in Central America, is recommended if genetic structure and status are to be restored.

Acute pesticide poisoning and pesticide registration in Central America

International Nuclear Information System (INIS)

Wesseling, Catharina; Corriols, Marianela; Bravo, Viria

2005-01-01

The International Code of Conduct on the Distribution and Use of Pesticides of the Food and Agriculture Organization (FAO) of the United Nations has been for 20 years the most acknowledged international initiative for reducing negative impact from pesticide use in developing countries. We analyzed pesticide use and poisoning in Central America, particularly in Costa Rica and Nicaragua, and evaluated whether registration decisions are based on such data, in accordance with the FAO Code. Extensive use of very hazardous pesticides continues in Central America and so do poisonings with organophosphates, carbamates, endosulfan and paraquat as the main causative agents. Central American governments do not carry out or commission scientific risk assessments. Instead, guidelines from international agencies are followed for risk management through the registration process. Documentation of pesticide poisonings during several decades never induced any decision to ban or restrict a pesticide. However, based on the official surveillance systems, in 2000, the ministers of health of the seven Central American countries agreed to ban or restrict twelve of these pesticides. Now, almost 4 years later, restrictions have been implemented in El Salvador and in Nicaragua public debate is ongoing. Chemical and agricultural industries do not withdraw problematic pesticides voluntarily. In conclusion, the registration processes in Central America do not comply satisfactorily with the FAO Code. However, international regulatory guidelines are important in developing countries, and international agencies should strongly extend its scope and influence, limiting industry involvement. Profound changes in international and national agricultural policies, steering towards sustainable agriculture based on non-chemical pest management, are the only way to reduce poisonings

Introduction: seismology and earthquake engineering in Central and South America.

Science.gov (United States)

Espinosa, A.F.

1983-01-01

Reports the state-of-the-art in seismology and earthquake engineering that is being advanced in Central and South America. Provides basic information on seismological station locations in Latin America and some of the programmes in strong-motion seismology, as well as some of the organizations involved in these activities.-from Author

Nutrition, poverty alleviation, and development in Central America and Panama.

Science.gov (United States)

Immink, Maarten D C

2010-03-01

This paper reviews research with policy relevance for food and nutrition in Central America and similar areas. The research was conducted by the Institute of Nutrition of Central America and Panama (INCAP) during the last three decades of the past millennium (1970-99). Six policy areas were selected for this review: agricultural commercialization and rural development; wage and price policies; human resource development; social safety nets, particularly complementary food programs; multi-sectoral nutrition planning; and food and nutrition monitoring for policy formulation. The contents and major conclusions of the work are described, as well as their public policy implications.

Smart power and foreign policy of the People's Republic of China: the case of Central America

Directory of Open Access Journals (Sweden)

Manuel Villegas Mendoza

2016-02-01

Full Text Available This paper presents the most relevant aspects of the academic debate on smart power, in order to apply this concept to analyze the foreign policy of the Republic of China on Latin America and the Caribbean, but especially to Central America; where the dispute between China and Taiwan for international recognition is evident. It is argued that the smart power of China to Central America is expressed in the attractiveness of having privileged access to the Chinese market and its funding programs and official development assistance. While this country has a large presence in Latin America and the Caribbean, in Central America such influence is counteracted in the light of the close relationship that all Central American countries except Costa Rica, maintain with Taiwan. Based on the development of China as a world power, it is expected that this condition changed, so that this country would increase its influence in Central America.

Assessing the 'Arrival of Democracy' in Central America

NARCIS (Netherlands)

K. Biekart (Kees)

2014-01-01

markdownabstract__Abstract__ Review Essay. In the 1970s and 1980s, Central America was associated with military governments, revolutionary movements, civil war, extreme inequality, and authoritarianism in the ‘backyard’ of the United States. Broad social mobilizations and political repression

Field Evaluations of Topical Arthropod Repellents in North, Central, and South America

Science.gov (United States)

2014-09-01

De La Rocque et al. 2011) and their spread into higher elevations of Africa, Latin America , and Asia (Epstein 2001). Dengue fever and...denguehemorrhagic fever have resurgeddramatically in Latin America (Zell 2004). In North America ,West Nile virus has impacted signiÞcantly the health and welfare of...VECTOR CONTROL, PEST MANAGEMENT, RESISTANCE, REPELLENTS Field Evaluations of Topical Arthropod Repellents in North, Central , and South America KENDRA

Medical genetic services in Latin America: report of a meeting of experts

Directory of Open Access Journals (Sweden)

Penchaszadeh Víctor B

1998-01-01

Full Text Available During the Ninth International Congress of Human Genetics which was held in Rio de Janeiro, Brazil, from 16 to 18 August 1996, a group of experts under the coordination of the authors discussed at length the state of medical genetics in Latin America. The facts and ideas presented at the meeting, which was sponsored by the Human Genetics Program of the World Health Organization (WHO and the Maternal and Child Health Program of the Pan American Health Organization, are examined in this document under three broad headings. The first verses on the history and current status of medical genetics in selected Latin American countries. This is followed by a discussion of the general features of medical genetics in the Region and by a final section of recommendations for promoting medical genetics in Latin America.

Narco-scapes: Cocaine Trafficking and Deforestation in Central America

Science.gov (United States)

Wrathall, D.; McSweeney, K.; Nielsen, E.; Pearson, Z.

2015-12-01

Narcotics trafficking and drug interdiction efforts have resulted in a well-documented social crisis in Central America, but more recently, has been tightly linked to environmental catastrophe and accelerated deforestation in transit zones. This talk will outline synthesis findings from multi-country, interdisciplinary research on cocaine trafficking as an engine of forest loss in Central America. During the "narco-boom" of the mid-2000s, we observed a geographical evolution of cocaine flows into Central America, and the transit of cocaine through new spaces, accompanied by specific patterns of social and environmental change in new nodes of transit. We coarsely estimated that the total amount of cocaine flowing through Central America increased from 70 metric tons in 2000 to 350 mt in 2012, implying that total cocaine trafficking revenue in the region increased from roughly 600 million dollars to 3.5 billion in that time. We describe the mechanism by which these locally captured cocaine rents resulted in a rapid conversion of forest into cattle pasture. Narco-traffickers are drawn to invest in the cattle economy, as a direct means of laundering and formalizing proceeds. Ranching is a land intensive activity, and new narco-enriched cattle pastures can be isolated from other forms forest loss solely by their spatial and temporal change characteristics. A preliminary forest change study in Honduras, for example, indicated that areas of accelerated deforestation were in close proximity to known narcotics trafficking routes and were thirteen times more extensive on average than other forest clearings. Deforested areas commonly appeared in isolated and biodiverse lowland tropical rainforest regions that often intersected with protected areas and indigenous reserves. We find that narco-deforestation is a readily identifiable signal of the extent and health of the cocaine economy. This talk will feature summaries of both ethnographic and land cover change we have observed

The Determinants of Banks' Liquidity Buffers in Central America

OpenAIRE

Corinne Deléchat; Camila Henao; Priscilla Muthoora; Svetlana Vtyurina

2014-01-01

Banks’ liquidity holdings are comfortably above legal or prudential requirements in most Central American countries. While good for financial stability, high liquidity may nonetheless hinder financial market development and monetary policy transmission. Using a panel of 96 commercial banks from Central America, Panama and the Dominican Republic for 2006-2010, we find that the demand for precautionary liquidity buffers is associated with measures of bank’s size, profitability, capitalization, ...

Neurocysticercosos in South-Central America and the Indian Subcontinent: a comparative evaluation

Directory of Open Access Journals (Sweden)

Gagandeep Singh

1997-09-01

Full Text Available Neurocysticercosis is an important public health problem in South-Central America and South Asia. A review of the differences in epidemiological and clinical attributes of cysticercosis and taeniasis in South Central America and India, respectively, is undertaken in the present communication. Intestinal taeniasis is hyperendemic in several American countries. In comparison, the prevalence of Taenia solium infestation is lower in India. The clinical manifestations in several American neurocysticercosis series comprise epilepsy, intracranial hypertension and meningeal - racemose cysticercosis, in roughly equal proportions. An overwhelming majority of the Indian subjects present with seizures. The commonest pathological substrate of the disorder in Indian patients is the solitary parenchymal degenerating cyst. The reasons for the predominance of solitary forms in India, and of multilesional forms in South Central America are discussed. The magnitude of Taenia solium infestation and the frequency of pork consumption in a given population appear to influence the quantum of cyst load in affected individuals.

Private Higher Education in a Cold War World: Central America

Science.gov (United States)

Harrington, James J.

2009-01-01

In Central America the Cold War support of the elites by the United States was designed to ward off the communist threat. At the same time social and economic demands by the working and middle classes created revolutionary movements in the face of rigid and violent responses by Central American governments. Issues of social justice pervaded the…

National Geothermal Association Trade Mission to Central America

International Nuclear Information System (INIS)

1992-10-01

The United States (US) geothermal industry, the world's most technically proficient, has been unable to achieve penetration into the markets of the developing nations. This report details the findings of an industry Trade Mission to Central America, tasked with determining the reasons for this shortfall and with developing a US industry geothermal export strategy designed to achieve immediate and long-term export benefits

Central and South America GPS geodesy - CASA Uno

Science.gov (United States)

Kellogg, James N.; Dixon, Timothy H.

1990-01-01

In January 1988, scientists from over 25 organizations in 13 countries and territories cooperated in the largest GPS campaign in the world to date. A total of 43 GPS receivers collected approximately 590 station-days of data in American Samoa, Australia, Canada, Colombia, Costa Rica, Ecuador, New Zealand, Norway, Panama, Sweden, United States, West Germany, and Venezuela. The experiment was entitled CASA Uno. Scientific goals of the project include measurements of strain in the northern Andes, subduction rates for the Cocos and Nazca plates beneath Central and South America, and relative motion between the Caribbean plate and South America. A second set of measurements are planned in 1991 and should provide preliminary estimates of crustal deformation and plate motion rates in the region.

National Geothermal Association Trade Mission to Central America

Energy Technology Data Exchange (ETDEWEB)

1992-10-01

The United States (US) geothermal industry, the world's most technically proficient, has been unable to achieve penetration into the markets of the developing nations. This report details the findings of an industry Trade Mission to Central America, tasked with determining the reasons for this shortfall and with developing a US industry geothermal export strategy designed to achieve immediate and long-term export benefits.

National Geothermal Association Trade Mission to Central America

Energy Technology Data Exchange (ETDEWEB)

1992-10-01

The United States (US) geothermal industry, the world`s most technically proficient, has been unable to achieve penetration into the markets of the developing nations. This report details the findings of an industry Trade Mission to Central America, tasked with determining the reasons for this shortfall and with developing a US industry geothermal export strategy designed to achieve immediate and long-term export benefits.

A five-century sedimentary geochronology of biomass burning in Nicaragua and Central America

International Nuclear Information System (INIS)

Suman, D.O.

1991-01-01

In spite of the extensive use of fire as an agricultural agent in Central America today, little is known of its history of biomass burning or agriculture. As an indicator of the burning practices on the adjacent land, a sedimentary record of carbonized particles sheds light on the trends in frequency and areal extent of biomass burning. This research focuses on a sediment core recovered from an anoxic site in the Pacific Ocean adjacent to the Central American Isthmus and reports a five-century record of charcoal deposition. The research illustrates that biomass burning has been an important ecological factor in the Pacific watershed of Central America at least during the past five centuries. Fluxes of charcoal have generally decreased toward the present suggesting a reduction in the charcoal source function. Perhaps, five centuries ago, the frequency of biomass burning was greater than it is today, larger areas were burned, or biomass per unit area of burned grassland was greater. The major type of biomass burned throughout this five-century period has been grass, as opposed to woods, indicating that any major deforestation of the Pacific watershed of Central America occurred prior to the Conquest

A biogeographical population genetics perspective of the colonization of cats in Latin America and temporal genetic changes in Brazilian cat populations

Directory of Open Access Journals (Sweden)

Manuel Ruiz-García

2008-01-01

Full Text Available We used nine morphological genes to analyze cat populations from Mexico, the Dominican Republic, the Colombian, Brazilian and Peruvian Amazon, Bolivia and Brazil. Most populations were in Hardy-Weinberg equilibrium at the O locus. The highest allele frequencies so far detected at world level for alleles I (inhibitor and L (long hair were found at La Paz (Bolivia. The analyses revealed at least five cat gene pools in Latin America: These findings suggest that the current genetic distribution of cats in Latin America correlates with the colonization of the Americas during the XIV to XVIII centuries. Additionally, the cat populations of São Paulo, Rio de Janeiro and Manaus were sampled, to compare their 1996-2003 genetic profiles with those obtained in 1983. Generally, these genetic profiles seem temporally stable, which is important for comparing cat populations sampled in different years and decades.

Genetic structure of Quechua-speakers of the Central Andes and geographic patterns of gene frequencies in South Amerindian populations.

Science.gov (United States)

Luiselli, D; Simoni, L; Tarazona-Santos, E; Pastor, S; Pettener, D

2000-09-01

A sample of 141 Quechua-speaking individuals of the population of Tayacaja, in the Peruvian Central Andes, was typed for the following 16 genetic systems: ABO, Rh, MNSs, P, Duffy, AcP1, EsD, GLOI, PGM1, AK, 6-PGD, Hp, Gc, Pi, C3, and Bf. The genetic structure of the population was analyzed in relation to the allele frequencies available for other South Amerindian populations, using a combination of multivariate and multivariable techniques. Spatial autocorrelation analysis was performed independently for 13 alleles to identify patterns of gene flow in South America as a whole and in more specific geographic regions. We found a longitudinal cline for the AcP1*a and EsD*1 alleles which we interpreted as the result of an ancient longitudinal expansion of a putative ancestral population of modern Amerindians. Monmonnier's algorithm, used to identify areas of sharp genetic discontinuity, suggested a clear east-west differentiation of native South American populations, which was confirmed by analysis of the distribution of genetic distances. We suggest that this pattern of genetic structures is the consequence of the independent peopling of western and eastern South America or to low levels of gene flow between these regions, related to different environmental and demographic histories. Copyright 2000 Wiley-Liss, Inc.

Visiting the Digital Divide: Women Entrepreneurs in Central America

Science.gov (United States)

Tapper, Helena

2006-01-01

Micro and small enterprises comprise approximately 60-70% of enterprises in South and Central America. Most of these enterprises, particularly micro enterprises, are managed and owned by women. These women for the most part lack both skills and training in the use of computers and the Internet, and access to the use of information and…

An analysis of Central America and Eastern Europe Revealed Comparative Advantages

Directory of Open Access Journals (Sweden)

Mauricio Garita Gutierrez

2014-03-01

Full Text Available Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0pt 5.4pt 0pt 5.4pt; mso-para-margin:0pt; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} The present study applies the revealed comparative advantages through the Balassa Index to determine the comparative advantages, disadvantages, and intra-product commerce tendencies between Central America and Eastern Europe with the purpose of determining the possibility of a free trade agreement for Central America. The approach of the study is through the connection between the European Economic Union and the Central American Common market, which shares a common background and relates them to research of Bela Balassa (1965 to determine how commerce between Central America and Eastern Europe has performed and the possibilities of growth that this commerce has through a free trade agreement. The study demonstrates the importance of analyzing competitive advantages. This paper presents the difference in competitive advantage between Eastern Europe and Central American establishing the benefits when negotiating a free trade agreement between both economic blocks. Therefore, analyzing and negotiating between products of competitive advantages may lead to a more sustainable economic growth.

Youth employment to reduce violence in Central America | CRDI ...

International Development Research Centre (IDRC) Digital Library (Canada)

According to 2014 statistics, four out of the 10 countries with the highest homicide rates in the world are in Central America. The vast majority of victims of violence are young men between the ages of 15 and 24, some of whom also risk becoming perpetrators of violence. Access to jobs, in both formal and informal labour ...

Addressing the Socioeconomic Impacts of Genetically Modified ...

International Development Research Centre (IDRC) Digital Library (Canada)

But despite rapid diffusion of genetically modified (GM) cotton - and ... Argentina, South America, Brazil, Paraguay, North and Central America, China, India, Pakistan ... A Expansão Da Cultura Do Algodão Transgênico Na Região Do Norte De ...

Molecular typing of canine distemper virus strains reveals the presence of a new genetic variant in South America.

Science.gov (United States)

Sarute, Nicolás; Pérez, Ruben; Aldaz, Jaime; Alfieri, Amauri A; Alfieri, Alice F; Name, Daniela; Llanes, Jessika; Hernández, Martín; Francia, Lourdes; Panzera, Yanina

2014-06-01

Canine distemper virus (CDV, Paramyxoviridae, Morbillivirus) is the causative agent of a severe infectious disease affecting terrestrial and marine carnivores worldwide. Phylogenetic relationships and the genetic variability of the hemagglutinin (H) protein and the fusion protein signal-peptide (Fsp) allow for the classification of field strains into genetic lineages. Currently, there are nine CDV lineages worldwide, two of them co-circulating in South America. Using the Fsp-coding region, we analyzed the genetic variability of strains from Uruguay, Brazil, and Ecuador, and compared them with those described previously in South America and other geographical areas. The results revealed that the Brazilian and Uruguayan strains belong to the already described South America lineage (EU1/SA1), whereas the Ecuadorian strains cluster in a new clade, here named South America 3, which may represent the third CDV lineage described in South America.

New views on American colonization: critical tests from South America

Directory of Open Access Journals (Sweden)

O'Rourke, Dennis

2007-01-01

Full Text Available The traditional view of colonization of the Americas as a migration across Beringia and subsequent dispersal southward following the last glacial maximum is being increasingly questioned. In North America, archaeological links to Siberia are tenuous and genetic data are more consistent with an earlier entry of people into the Americas, from Central rather than Northeast Siberia. An entry of populations into the Americas prior to the last glacial maximum forces a reconsideration not only of timing, but also geographic points of entry and speed of dispersal, based on ecological theory. A number of emerging alternative hypotheses on the colonization of the Americas predict early entry and dispersal of people into South America - earlier than, or coeval with, initial dispersal in North America. The study of genetic, morphological, and archaeological variation across South America is critical to testing these new, alternative hypotheses of Native American origins. I will review the evidence for emerging, alternative views of American Colonization, and suggest ways in which data from South American populations and prehistory will be crucial in testing them.

Development of Renewable Energies in the liberation of the energy market in Central America

International Nuclear Information System (INIS)

Rebollo, Jose; Puente, Margarita; Cabezas, Jose

2000-01-01

This paper presents the diagnostic of the current situation on renewable energy in Central America, including socio-economical situation, with economical index, supply and demand of energy and planning of wind resources. The experience of Europe in the promotion for the market of renewable energy, discussing the policies and cooperation between private sector and the government is included. A list of potential projects of renewable energy in each country of Central America based on biomass, hydro power, wind and other energy sources for power generation is presented

Water Security and Climate Change in Central America and the ...

International Development Research Centre (IDRC) Digital Library (Canada)

Recent studies show that water shortages in Central America and the Caribbean will be aggravated by urban growth, high poverty rates, weak institutions, and insufficient investment in water and sanitation infrastructure. Extreme climatic events are expected to further threaten water supply as well as affect economic sectors ...

Legal Central Bank Independence and Inflation in Latin America During the 1990s

OpenAIRE

Luis Ignacio Jácome

2001-01-01

This paper reviews central banks' legal reform in Latin America during the 1990s and discusses the status of central bank independence in the region. Based on this information, it builds a simplified index of central bank independence which, in addition to the commonly used criteria of political and economic independence, incorporates provisions of central banks' financial autonomy, accountability, and lender-of-last-resort. The paper finds a moderate negative correlation between increased ce...

Post Doctorate Award on Central America and the Caribbean at St ...

International Development Research Centre (IDRC) Digital Library (Canada)

English · Français ... a 2-year post doctoral position on Central America and the Caribbean under the leadership of Canadian historian, Margaret MacMillan. ... Between 1965 and 2000, about 12% of the Caribbean labour force moved to ...

Ethical issues in genetics and public health in Latin America with a focus on Argentina.

Science.gov (United States)

Penchaszadeh, Victor B

2015-07-01

This paper reviews the health situation and developments in medical genetics and bioethics in Latin America, with a focus on Argentina. The region is the most inequitable in the world, with an average Gini Index of 52.5 and 25 % of the population living in poverty. Health expenditures are low and health systems are fragmented and privatised, with curtailed governmental responsibility and regulation. Health-care decision making is mostly in the hands of private insurance corporations and the medical-industrial complex, so that what is (or is not) covered by health plans is arbitrary and determined by the market and not by population health needs. This inequity and the lack of meaningful governmental intervention in the provision of health care, including genetic services, are at the heart of the bioethical dilemmas in Latin America. It is not surprising, therefore, that bioethics in the region has developed an approach grounded in social justice, equity and human rights as guiding principles, in contrast to the individualism espoused by Anglo-Saxon bioethics. The main ethical issues identified in genetics in Latin America are (1) inequity in access to genetic services, particularly in prenatal diagnosis, (2) genetic discrimination and (3) the lack of adherence to internationally accepted requisites of clinical validity and utility for diagnostic and predictive genetic testing. In this context, there is a risk that the impressive advances in genetics/genomics occurring in developed countries may fail to improve the public's health and deepen inequity, with the implementation of expensive genetic technologies of unproven validity.

Mineral deposits of Central America, with a section on manganese deposits of Panama

Science.gov (United States)

Roberts, Ralph Jackson; Irving, Earl Montgomery; Simons, F.S.

1957-01-01

The mineral deposits of Central America were studied between 1942 and 1945, in cooperation with the United States Department of State and the Foreign Economic Administration. Emphasis was originally placed on the study of strategic-mineral deposits, especially of antimony, chromite, manganese, quartz, and mica, but deposits of other minerals that offered promise of significant future production were also studied. A brief appraisal of the base-metal deposits was made, and deposits of iron ore in Honduras and of lead and zinc ores in Guatemala were mapped. In addition, studies were made of the regional geology of some areas, data were collected from many sources, and a new map of the geology of Central America was compiled.

Evolution of the Earthquake Catalog in Central America

Science.gov (United States)

Rojas, W.; Camacho, E. I.; Marroquín, G.; Molina, E.; Talavera, E.; Benito, M. B.; Lindholm, C.

2013-05-01

Central America (CA) is known as a seismically active region in which several historic destructive earthquakes have occurred. This fact has promoved the development of seismic hazard studies that provide necessary estimates for decision making and risk assessment efforts, requiring a complete and standardized seismic catalog. With this aim, several authors have contributed to the study of the historical seismicity of Central America (e.g. Grases, Feldaman; White y Harlow, 1993; White et al. 2004; Ambraseys y Adams, 2001; Peraldo y Montero, 1999), who complied historical data. A first catalogue was developed by Rojas (1993) that comprises the 1522 to 1993 period. This information was integrated in 2007, together with data from the International Seismological Centre (CASC) and the national catalogs of CA countries in a new regional catalogue. Since 2007 a continuous effort has been done in order to complete and update this CA earthquake catalog. In particular, two workshops were held in 2008 and 2011 in the Universidad Politécnica de Madrid (Spain), joining experts from the different CA countries who worked each one in its own catalogue covering the entire region and the border with northwestern Colombia and southern Mexico. These national catalogues were later integrated in a common regional catalogue in SEISAN format. At this aim it was necessary to solve some problems, like to avoid duplicity of events, specially close to the boundaries, to consider the different scales of magnitude adopted by different countries, to take into account the completeness by the different national networks, etc. Some solutions were adopted for obtaining a homogenized catalogue to Mw, containing historical and instrumental events with Mw > 3.5 from 1522 up to 2011. The catalogue updated to December 2007 was the basis for the first regional hazard study carried out by Benito et al., (2011) as part of the collaborative RESIS II project under coordination of NORSAR. The ones updated to

Mexico and Central America.

Science.gov (United States)

Bronfman, M

1998-01-01

This article reviews the literature on migration and HIV/AIDS in Mexico and Central America, including Belize, Costa Rica, El Salvador, Guatemala, Honduras, Mexico, Nicaragua, and Panama. Most migrants travel to the US through Mexico. US-Mexico trade agreements created opportunities for increased risk of HIV transmission. The research literature focuses on Mexico. Most countries, with the exception of Belize and Costa Rica, are sending countries. Human rights of migrants are violated in transit and at destination. Migration policies determine migration processes. The Mexican-born population in the US is about 3% of US population and 8% of Mexico's population. About 22% arrived during 1992-97, and about 500,000 are naturalized US citizens. An additional 11 million have a Mexican ethnic background. Mexican migrants are usually economically active men who had jobs before leaving and were urban people who settled in California, Texas, Illinois, and Arizona. Most Mexican migrants enter illegally. Many return to Mexico. The main paths of HIV transmission are homosexual, heterosexual, and IV-drug-injecting persons. Latino migrants frequently use prostitutes, adopt new sexual practices including anal penetration among men, greater diversity of sexual partners, and use of injectable drugs.

Sources of Economic Fluctuations in Central America

Directory of Open Access Journals (Sweden)

Wilfredo Toledo

2014-06-01

Full Text Available Using panel data from Central America, this paper studies the determining factors of inflation and aggregate output fluctuations by estimating two Structural Vector Autoregressive (SVAR models. Price and output variables are included in one of the models, whereas M2 and the price of oil are additional variables in the other one. Findings of this study suggest that price is determined by the demand, while output seems to be influenced mainly by the supply shocks in that area. It was also evidenced that the price of oil does not have a significant impact on the general price level in that region.

"Central America in the World Economy of the 21st Century" phases ...

International Development Research Centre (IDRC) Digital Library (Canada)

Fernando Loayza

on fiscal and taxation challenges of Central America economic integration. ..... second phase, supporting research studies by assignment was adopted along ..... Fees fluctuated between US$ 10,000 to 15,000 to cover the costs of two or three ...

Circulation of different lineages of dengue virus type 2 in Central America, their evolutionary time-scale and selection pressure analysis.

Directory of Open Access Journals (Sweden)

Germán Añez

Full Text Available Dengue is caused by any of the four serotypes of dengue virus (DENV-1 to 4. Each serotype is genetically distant from the others, and each has been subdivided into different genotypes based on phylogenetic analysis. The study of dengue evolution in endemic regions is important since the diagnosis is often made by nucleic acid amplification tests, which depends upon recognition of the viral genome target, and natural occurring mutations can affect the performance of these assays. Here we report for the first time a detailed study of the phylogenetic relationships of DENV-2 from Central America, and report the first fully sequenced DENV-2 strain from Guatemala. Our analysis of the envelope (E protein and of the open reading frame of strains from Central American countries, between 1999 and 2009, revealed that at least two lineages of the American/Asian genotype of DENV-2 have recently circulated in that region. In occasions the co-circulation of these lineages may have occurred and that has been suggested to play a role in the observed increased severity of clinical cases. Our time-scale analysis indicated that the most recent common ancestor for Central American DENV-2 of the American/Asian genotype existed about 19 years ago. Finally, we report positive selection in DENV-2 from Central America in codons of the genes encoding for C, E, NS2A, NS3, and NS5 proteins. Some of these identified codons are novel findings, described for the first time for any of the DENV-2 genotypes.

Genetic and morphological divergence among Cooper's Hawk (Accipiter cooperii) populations breeding in north-central and western North America

Science.gov (United States)

Sonsthagen, Sarah A.; Rosenfield, Robert N.; Bielefeldt, John; Murphy, Robert K.; Stewart, Andrew C.; Stout, William C.; Driscoll, Timothy G.; Bozek, Michael A.; Sloss, Brian L.; Talbot, Sandra L.

2012-01-01

Cooper's Hawk (Accipiter cooperii) populations breeding in the northern portion of the species' range exhibit variation in morphological traits that conforms to predictions based on differences in prey size, tree stand density, and migratory behavior. We examined genetic structure and gene flow and compared divergence at morphological traits (PST) and genetic markers (FST) to elucidate mechanisms (selection or genetic drift) that promote morphological diversification among Cooper's Hawk populations. Cooper's Hawks appear to conform to the genetic pattern of an east-west divide. Populations in British Columbia are genetically differentiated from north-central populations (Wisconsin, Minnesota, and North Dakota; pairwise microsatellite FST= 0.031-0.050; mitochondrial DNA ΦST = 0.177-0.204), which suggests that Cooper's Hawks were restricted to at least two Pleistocene glacial refugia. The strength of the Rocky Mountains—Great Plains area as a barrier to dispersal is further supported by restricted gene-flow rates between British Columbia and other sampled breeding populations. Divergence in morphological traits (PST) was also observed across study areas, but with British Columbia and North Dakota differentiated from Wisconsin and Minnesota, a pattern not predicted on the basis of FST and ΦST interpopulation estimates. Comparison of PSTand FSTestimates suggests that heterogeneous selection may be acting on Cooper's Hawks in the northern portion of their distribution, which is consistent with hypotheses that variation in prey mass and migratory behavior among populations may be influencing overall body size and wing chord. We were unable to distinguish between the effects of genetic drift and selection on tail length in the study populations.

How does the North American Free Trade Agreement (NAFTA) affect Central America?

OpenAIRE

Leamer, Edward E.; Guerra, Alfonso; Kaufman, Martin; Segura, Boris

1995-01-01

Most Central American economies experienced slower growth in the 1980s than in the 1960s and 1970s, trailing far behind the Asian Tigers. Contributing to slow growth were severe external shocks, sizable macroeconomic disturbances, and widespread political instability. The challenges Central America faces now may be even greater, conclude the authors, because of Mexican liberalization, continuing instability of the real exchange rate, low savings rates, and, finally, the North American Free Tr...

The implications of trade liberalization for diet and health: a case study from Central America.

Science.gov (United States)

Thow, Anne Marie; Hawkes, Corinna

2009-07-28

Central America has undergone extensive trade liberalization over the past two decades, and has recently signed a Free Trade Agreement with the United States. The region is also experiencing a dual burden of malnutrition with the growth of dietary patterns associated with the global 'nutrition transition'. This study describes the relationship between trade liberalization policies and food imports and availability, and draws implications for diet and health, using Central America as a case study region. Changes in tariff and non-tariff barriers for each country were documented, and compared with time-series graphs of import, production and availability data to show the outcome of changes in trade policy in relation to food imports and food availability. Changes in trade policy in Central America have directly affected food imports and availability via three avenues. First, the lowering of trade barriers has promoted availability by facilitating higher imports of a wide range of foods. Second, trade liberalization has affected food availability through promoting domestic meat production. Third, reductions in barriers to investment appear to be critical in expansion of processed food markets. This suggests that changes in trade policies have facilitated rising availability and consumption of meat, dairy products, processed foods and temperate (imported fruits) in Central America. This study indicates that the policies of trade liberalization in Central American countries over the past two decades, particularly in relation to the United States, have implications for health in the region. Specifically, they have been a factor in facilitating the "nutrition transition", which is associated with rising rates of obesity and chronic diseases such as cardiovascular disease and cancer. Given the significant cost of chronic disease for the health care system, individuals and the wider community, it is critical that preventive health measures address such upstream determinants

The implications of trade liberalization for diet and health: a case study from Central America

Directory of Open Access Journals (Sweden)

Hawkes Corinna

2009-07-01

Full Text Available Abstract Background Central America has undergone extensive trade liberalization over the past two decades, and has recently signed a Free Trade Agreement with the United States. The region is also experiencing a dual burden of malnutrition with the growth of dietary patterns associated with the global 'nutrition transition'. This study describes the relationship between trade liberalization policies and food imports and availability, and draws implications for diet and health, using Central America as a case study region. Methods Changes in tariff and non-tariff barriers for each country were documented, and compared with time-series graphs of import, production and availability data to show the outcome of changes in trade policy in relation to food imports and food availability. Results Changes in trade policy in Central America have directly affected food imports and availability via three avenues. First, the lowering of trade barriers has promoted availability by facilitating higher imports of a wide range of foods. Second, trade liberalization has affected food availability through promoting domestic meat production. Third, reductions in barriers to investment appear to be critical in expansion of processed food markets. This suggests that changes in trade policies have facilitated rising availability and consumption of meat, dairy products, processed foods and temperate (imported fruits in Central America. Conclusion This study indicates that the policies of trade liberalization in Central American countries over the past two decades, particularly in relation to the United States, have implications for health in the region. Specifically, they have been a factor in facilitating the "nutrition transition", which is associated with rising rates of obesity and chronic diseases such as cardiovascular disease and cancer. Given the significant cost of chronic disease for the health care system, individuals and the wider community, it is critical

Post Doctorate Award on Central America and the Caribbean at St ...

International Development Research Centre (IDRC) Digital Library (Canada)

This grant will allow St Antony's College at the University of Oxford to establish a 2-year post doctoral position on Central America and the Caribbean under the leadership of Canadian historian, Margaret MacMillan. The position will be awarded to a scholar from the region, in keeping with IDRC's philosophy that developing ...

Capacity-Building Programs Under the Dominican Republic-Central America-United States Free Trade Agreement (CAFTA-DR)

Science.gov (United States)

The United States signed the Dominican Republic-Central America-United States Free Trade Agreement (CAFTA-DR) in August 2004 with five Central American countries (Costa Rica, El Salvador, Guatemala, Honduras, and Nicaragua) and the Dominican Republic.

Health outcomes among HIV-positive Latinos initiating antiretroviral therapy in North America versus Central and South America

Science.gov (United States)

Cesar, Carina; Koethe, John R; Giganti, Mark J; Rebeiro, Peter; Althoff, Keri N; Napravnik, Sonia; Mayor, Angel; Grinsztejn, Beatriz; Wolff, Marcelo; Padgett, Denis; Sierra-Madero, Juan; Gotuzzo, Eduardo; Sterling, Timothy R; Willig, James; Levison, Julie; Kitahata, Mari; Rodriguez-Barradas, Maria C; Moore, Richard D; McGowan, Catherine; Shepherd, Bryan E; Cahn, Pedro

2016-01-01

Introduction Latinos living with HIV in the Americas share a common ethnic and cultural heritage. In North America, Latinos have a relatively high rate of new HIV infections but lower rates of engagement at all stages of the care continuum, whereas in Latin America antiretroviral therapy (ART) services continue to expand to meet treatment needs. In this analysis, we compare HIV treatment outcomes between Latinos receiving ART in North America versus Latin America. Methods HIV-positive adults initiating ART at Caribbean, Central and South America Network for HIV (CCASAnet) sites were compared to Latino patients (based on country of origin or ethnic identity) starting treatment at North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) sites in the United States and Canada between 2000 and 2011. Cox proportional hazards models compared mortality, treatment interruption, antiretroviral regimen change, virologic failure and loss to follow-up between cohorts. Results The study included 8400 CCASAnet and 2786 NA-ACCORD patients initiating ART. CCASAnet patients were younger (median 35 vs. 37 years), more likely to be female (27% vs. 20%) and had lower nadir CD4 count (median 148 vs. 195 cells/µL, p<0.001 for all). In multivariable analyses, CCASAnet patients had a higher risk of mortality after ART initiation (adjusted hazard ratio (AHR) 1.61; 95% confidence interval (CI): 1.32 to 1.96), particularly during the first year, but a lower hazard of treatment interruption (AHR: 0.46; 95% CI: 0.42 to 0.50), change to second-line ART (AHR: 0.56; 95% CI: 0.51 to 0.62) and virologic failure (AHR: 0.52; 95% CI: 0.48 to 0.57). Conclusions HIV-positive Latinos initiating ART in Latin America have greater continuity of treatment but are at higher risk of death than Latinos in North America. Factors underlying these differences, such as HIV testing, linkage and access to care, warrant further investigation. PMID:26996992

[Trends in the urbanization process in Central America in the 1980's].

Science.gov (United States)

Lungo Ucles, M

1990-01-01

In the 1980s, urbanization in Central America was increasing compared to the three previous decades. By 1990, the urban population reached 42% in Guatemala, 44% in El Salvador, 43% in Honduras, 59% in Nicaragua, 53% in Costa Rica, and 54% in Panama. The urban population increased mostly in the largest cities, in contrast to Latin America, where secondary cities grew fastest. This trend was particularly true in Managua and San Salvador because of the military conflicts. The only exception was Honduras, where the second city underwent stronger growth. The urban population comprised 51.7% women and 48.3% men in Central America. The segregation and polarization of social classes was also increasing because of increased poverty and unemployment during the 1980s. This was partly caused by the increasing privatization of public services, decentralization, and the reinforcement of local governments, which all ensued from the structural readjustment programs of the International Monetary Fund. This neoliberal model of economic development in the short run resulted in increased poverty and unemployment for the urban populations. In 1982, the informal sector represented 29% of the total employment in Central America, and its share reached 40% in Managua and San Salvador. Urban unemployment increased from 2.2% in 1980 to 12% in 1988 in Guatemala; from 8.8% to 13.1% in Honduras; and from 10.4% to 20.8% in Panama. In the political arena, the process of democratization was underway, with civil presidents taking power and promoting privatization and deregulation of the economy. There was a close relationship between the urban social structure, the economy, and politics in the region. In Costa Rica, during the Arias administration between 1986 and 1990, a program was implemented creating 80,000 new homes, and in El Salvador there was an increasing demand to find a negotiated solution to the military conflict. These new political and economic perspectives could lead to genuine

Team Massachusetts & Central America Solar Decathlon 2015 Final Technical Report

Energy Technology Data Exchange (ETDEWEB)

Lee, Kenneth [Western New England Univ., Springfield, MA (United States)

2016-04-29

Our team was Team MASSCA (Massachusetts and Central America), which was a partnership of Western New England University (WNE) located in Massachusetts USA, The Technological University of Panama (UTP), and Central American Technological University (UNITEC) of Honduras. Together we had a group of 6 faculty members and approximately 30 undergraduate students. Our house is ‘The EASI’ House, which stands for Efficient, Affordable, Solar Innovation. The EASI house is rectangular with two bedrooms and one bath, and offers a total square footage of 680. Based on competition estimates, The EASI house costs roughly $121,000. The EASI house has a 5kW solar system. Faculty and students from all three institutions were represented at the competition in Irvine California. Team MASSCA did well considering this was our first entry in the Solar Decathlon competition. Team MASSCA won the following awards: First Place – Affordability Contest Second Place – Energy Balance Contest. The competition provided a great experience for our students (and faculty as well). This competition provided leadership, endurance, and technical knowledge/skills for our students, and was the single most important hands-on experience during their undergraduate years. We are extremely pleased with the awards we received. At the same time we have learned from our efforts and would do better if we were to compete in the future. Furthermore, as a result of our team’s Inter-Americas collaborative effort, UTP and WNE have partnered to form Team PANAMASS (PANAma and MASSachusetts) and have developed The 3 SMART House for the inaugural Solar Decathlon Latin America & Caribbean competition held in Colombia.

Xylella fastidiosa CoDiRO strain associated with the olive quick decline syndrome in southern Italy belongs to a clonal complex of the subspecies pauca that evolved in Central America.

Science.gov (United States)

Marcelletti, Simone; Scortichini, Marco

2016-12-01

Xylella fastidiosa, a xylem-limited bacterium transmitted by xylem-fluid-feeding Hemiptera insects, causes economic losses of both woody and herbaceous plant species. A Xyl. fastidiosa subsp. pauca strain, namely CoDiRO, was recently found to be associated with the 'olive quick decline syndrome' in southern Italy (i.e. Apulia region). Recently, some Xyl. fastidiosa strains intercepted in France from Coffea spp. plant cuttings imported from Central and South America were characterized. The introduction of infected plant material from Central America in Apulia was also postulated even though an ad hoc study to confirm this hypothesis is lacking. In the present study, we assessed the complete and draft genome of 27 Xyl. fastidiosa strains. Through a genome-wide approach, we confirmed the occurrence of three subspecies within Xyl. fastidiosa, namely fastidiosa, multiplex and pauca, and demonstrated the occurrence of a genetic clonal complex of four Xyl. fastidiosa strains belonging to subspecies pauca which evolved in Central America. The CoDiRO strain displayed 13 SNPs when compared with a strain isolated in Costa Rica from Coffea sp. and 32 SNPs when compared with two strains obtained from Nerium oleander in Costa Rica. These results support the close relationships of the two strains. The four strains in the clonal complex contain prophage-like genes in their genomes. This study strongly supports the possibility of the introduction of Xyl. fastidiosa in southern Italy via coffee plants grown in Central America. The data also stress how the current global circulation of agricultural commodities potentially threatens the agrosystems worldwide.

Prevalence of metabolic syndrome in Central America: a cross-sectional population-based study

Directory of Open Access Journals (Sweden)

Roy A. Wong-McClure

2015-09-01

Full Text Available OBJECTIVE: To report the prevalence of metabolic syndrome (MetS as found by the Central American Diabetes Initiative (CAMDI study for five major Central American populations: Belize (national; Costa Rica (San José; Guatemala (Guatemala City; Honduras (Tegucigalpa; and Nicaragua (Managua. METHODS: Study data on 6 185 adults aged 20 years or older with anthropometric and laboratory determination of MetS from population-based surveys were analyzed. Overall, the survey response rate was 82.0%. MetS prevalence was determined according to criteria from the Adult Treatment Panel III of the National Cholesterol Education Program. The study's protocol was reviewed and approved by the bioethical committee of each country studied. RESULTS: The overall standardized prevalence of MetS in the Central American region was 30.3% (95% confidence interval (CI: 27.1-33.4. There was wide variability by gender and work conditions, with higher prevalence among females and unpaid workers. The standardized percentage of the population free of any component of MetS was lowest in Costa Rica (9.0%; CI: 6.5-11.4 and highest in Honduras (21.1%; CI: 16.4-25.9. CONCLUSIONS: Overall prevalence of MetS in Central America is high. Strengthening surveillance of chronic diseases and establishing effective programs for preventing cardiovascular diseases might reduce the risk of MetS in Central America.

[Musculoskeletal pain in Central American workers: results of the First Survey on Working Conditions and Health in Central America].

Science.gov (United States)

Rojas, Marianela; Gimeno, David; Vargas-Prada, Sergio; Benavides, Fernando G

2015-08-01

Examine the prevalence of musculoskeletal pain (MSP) in the six Spanish-speaking countries of Central America using a single standardized instrument, the First Survey on Working Conditions and Health in Central America in workers from all manual and non-manual labor sectors, using social security coverage as an indicator of formal versus informal employment. The workers (n = 12 024) were surveyed in their homes. The age-adjusted prevalence of MSP during the previous month was calculated for pain in the back (upper, or cervical; middle, or thoracic; and lower, or lumbar) and arm joints (shoulder, elbow, and wrist). Prevalence was estimated by sex, occupation (manual or non-manual), economic sector (agriculture, industry, or services), and social security coverage. Poisson regression models were used to calculate the prevalence rates and 95% confidence intervals, with stratification by country and anatomical site. By sites, the age-adjusted prevalence of cervical-dorsal MSP was the highest, especially in El Salvador (47.8%) and Nicaragua (45.9%), and lumbar MSP was less prevalent, especially in Panama (12.8%) and Guatemala (14.8%). After additional adjustments, the prevalence of MSP was higher in women and manual workers for all the sites and in all the countries. There were no differences in MSP in terms of social security coverage or sector of economic activity. The high prevalence of MSP in Central America, regardless of sector of activity or social security coverage, indicates that the prevention of MSP should be a priority in occupational health programs in low- and middle-income countries, especially for women and manual workers.

Covariability of Central America/Mexico winter precipitation and tropical sea surface temperatures

Science.gov (United States)

Pan, Yutong; Zeng, Ning; Mariotti, Annarita; Wang, Hui; Kumar, Arun; Sánchez, René Lobato; Jha, Bhaskar

2018-06-01

In this study, the relationships between Central America/Mexico (CAM) winter precipitation and tropical Pacific/Atlantic sea surface temperatures (SSTs) are examined based on 68-year (1948-2015) observations and 59-year (1957-2015) atmospheric model simulations forced by observed SSTs. The covariability of the winter precipitation and SSTs is quantified using the singular value decomposition (SVD) method with observational data. The first SVD mode relates out-of-phase precipitation anomalies in northern Mexico and Central America to the tropical Pacific El Niño/La Niña SST variation. The second mode links a decreasing trend in the precipitation over Central America to the warming of SSTs in the tropical Atlantic, as well as in the tropical western Pacific and the tropical Indian Ocean. The first mode represents 67% of the covariance between the two fields, indicating a strong association between CAM winter precipitation and El Niño/La Niña, whereas the second mode represents 20% of the covariance. The two modes account for 32% of CAM winter precipitation variance, of which, 17% is related to the El Niño/La Niña SST and 15% is related to the SST warming trend. The atmospheric circulation patterns, including 500-hPa height and low-level winds obtained by linear regressions against the SVD SST time series, are dynamically consistent with the precipitation anomaly patterns. The model simulations driven by the observed SSTs suggest that these precipitation anomalies are likely a response to tropical SST forcing. It is also shown that there is significant potential predictability of CAM winter precipitation given tropical SST information.

Different educational glances in two pedagogical congresses : Cuba (1884 and Central America (1893

Directory of Open Access Journals (Sweden)

Amalia Nivón Bolán

2014-12-01

Full Text Available The 19th Century pedagogical congresses carried out in Cuba and Central America were led by teachers and officials involved in the educational policy of primary education, and aware of the need to adjust the education’s foundation in order to react to the moment’s reality. This piece analyses the special conditions in Cuba and Central America that cause the reform of the primary education grounds that prevailed in schools during the Colony in the 18th and 19th Centuries. It also describes the protagonists in the educational practice elite that influenced the restruturing of the school system, knowledge and learning techniques, as well as the teachers’ educational or occupational profile. In addition, it outlines the economic circumstances and the political view of the groups of intellectuals trained in a context that inherited the legacy of the colonial conditions of racism and defense of agricultural and industrial work, and defined by abolitionist and pro-independence struggles.  The study was conducted from the UNESCO Memory of the First Central Pedagogical Congress and current research that relate to the Cuban Congress 1884, to identify educational activities and careers of influential intellectuals in shaping Cuban and Central American educational systems at sundown nineteenth century.

Interconnected power systems of the countries of America Central (SIEPAC)

International Nuclear Information System (INIS)

2002-01-01

This presentation shows the project SIEPAC (Sistema de interconexion electrica de los paises de Centro America) describes the current transmission system, and planned SIEPAC transmission system, also describes the objectives: implementation of an central american electrical market named Mercado Electrico Regional that contributes to sustaintable development of the region. Also describes the power transmission lines, the structure of line transmission and its market to be covered. Financing of the project from lending institutions is explained

Catalogo General de Universidades, 1970-1971: Federacion de Universidades Privadas de America Central y Panama (General Catalog of Universities, 1970-1971: Federation of Private Universities of Central America and Panama).

Science.gov (United States)

Federacion de Universidades Privadas de America Central y Panama, Guatemala City (Guatemala).

This document contains the 1970-1971 catalogues of five universities belonging to the Federation of Private Universities of Central America and Panama (FUPAC). The catalogues provide information on university administrators and staff, historical background, admission requirements, degree programs, scholarships, and courses. The catalogues included…

An Overview of School Dropout in Central America: Unresolved Issues and New Challenges for Education Progress

Science.gov (United States)

Adelman, Melissa A.; Székely, Miguel

2017-01-01

School dropout is a growing concern in Central America, and in Latin America as a whole, because of its consequences for economic productivity, the inclusiveness of growth, social cohesion, and increasing youth risks. This paper utilizes more than two decades of household survey data to construct a systematic overview of school dropout at the…

Medicinal plants used to treat snakebite in Central America: Review and assessment of scientific evidence.

Science.gov (United States)

Giovannini, Peter; Howes, Melanie-Jayne R

2017-03-06

Every year between 1.2 and 5.5 million people worldwide are victims of snakebites, with about 400,000 left permanently injured. In Central America an estimated 5500 snakebite cases are reported by health centres, but this is likely to be an underestimate due to unreported cases in rural regions. The aim of this study is to review the medicinal plants used traditionally to treat snakebites in seven Central American countries: Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama. A literature search was performed on published primary data on medicinal plants of Central America and those specifically pertaining to use against snakebites. Plant use reports for traditional snakebite remedies identified in primary sources were extracted and entered in a database, with data analysed in terms of the most frequent numbers of use reports. The scientific evidence that might support the local uses of the most frequently reported species was also examined. A total of 260 independent plant use reports were recorded in the 34 sources included in this review, encompassing 208 species used to treat snakebite in Central America. Only nine species were reported in at least three studies: Cissampelos pareira L., Piper amalago L., Aristolochia trilobata L., Sansevieria hyacinthoides (L.) Druce, Strychnos panamensis Seem., Dorstenia contrajerva L., Scoparia dulcis L., Hamelia patens Jacq., and Simaba cedron Planch. Genera with the highest number of species used to treat snakebite were Piper, Aristolochia, Hamelia, Ipomoea, Passiflora and Peperomia. The extent of the scientific evidence available to understand any pharmacological basis for their use against snakebites varied between different plant species. At least 208 plant species are traditionally used to treat snakebite in Central America but there is a lack of clinical research to evaluate their efficacy and safety. Available pharmacological data suggest different plant species may target different symptoms of

Energy integration experiences at the Europe, at the Nordic countries and at the Central America: considerations relevant to the South America integration process; Experiencias de integracao energetica na Europa, nos paises nordicos e na America Central: consideracoes relevantes ao processo de integracao Sul-Americana

Energy Technology Data Exchange (ETDEWEB)

Campos, Adriana Fiorotti; Andreza, Fernanda Marques Pereira; Soares, Jeferson Borghetti; Pinheiro, Maria Fernanda Bacile; Oliveira, Ricardo Gorini de [Empresa de Pesquisa Energetica (EPE), Rio de Janeiro, RJ (Brazil)], Emails: adriana.campos@epe.gov.br, fernanda.andreza@epe.gov.br; jeferson.soares@epe.gov.br, maria.pinheiro, ricardo.gorini@epe.gov.br

2010-07-01

In view of institutional/contractual regulatory problems at the South America, some experiences of energy integration at the electrical sectors and natural gas (Nordic countries. European Union and Central America), identifying related vantages and advantageous. Besides, there is an attempt of characterization of the process step of energy integration, and the fitting of regions in these steps, observing that the process of energy integration in the South America it is found in a initial step yet if it is considered the used methodology by the Colombian enterprise Interconexion Electrica S.A.E.S.P. - ISA (2007)

Plate rotations, fault slip rates, fault locking, and distributed deformation in northern Central America from 1999-2017 GPS observations

Science.gov (United States)

Ellis, A. P.; DeMets, C.; Briole, P.; Cosenza, B.; Flores, O.; Guzman-Speziale, M.; Hernandez, D.; Kostoglodov, V.; La Femina, P. C.; Lord, N. E.; Lasserre, C.; Lyon-Caen, H.; McCaffrey, R.; Molina, E.; Rodriguez, M.; Staller, A.; Rogers, R.

2017-12-01

We describe plate rotations, fault slip rates, and fault locking estimated from a new 100-station GPS velocity field at the western end of the Caribbean plate, where the Motagua-Polochic fault zone, Middle America trench, and Central America volcanic arc faults converge. In northern Central America, fifty-one upper-plate earthquakes caused approximately 40,000 fatalities since 1900. The proximity of main population centers to these destructive earthquakes and the resulting loss of human life provide strong motivation for studying the present-day tectonics of Central America. Plate rotations, fault slip rates, and deformation are quantified via a two-stage inversion of daily GPS position time series using TDEFNODE modeling software. In the first stage, transient deformation associated with three M>7 earthquakes in 2009 and 2012 is estimated and removed from the GPS position time series. In Stage 2, linear velocities determined from the corrected GPS time series are inverted to estimate deformation within the western Caribbean plate, slip rates along the Motagua-Polochic faults and faults in the Central America volcanic arc, and the gradient of extension in the Honduras-Guatemala wedge. Major outcomes of the second inversion include the following: (1) Confirmation that slip rates on the Motagua fault decrease from 17-18 mm/yr at its eastern end to 0-5 mm/yr at its western end, in accord with previous results. (2) A transition from moderate subduction zone locking offshore from southern Mexico and parts of southern Guatemala to weak or zero coupling offshore from El Salvador and parts of Nicaragua along the Middle America trench. (3) Evidence for significant east-west extension in southern Guatemala between the Motagua fault and volcanic arc. Our study also shows evidence for creep on the eastern Motagua fault that diminishes westward along the North America-Caribbean plate boundary.

Review of the genera of Conoderinae (Coleoptera, Curculionidae from North America, Central America, and the Caribbean

Directory of Open Access Journals (Sweden)

Salvatore S. Anzaldo

2017-07-01

Full Text Available The thirty-nine extant genera of Conoderinae known to occur in North America, Central America, and the Caribbean are reviewed based on external morphology. An identification key is provided along with diagnoses, distributions, species counts, and natural history information, when known, for each genus. Morphological character systems of importance for weevil classification are surveyed, potential relationships among the tribes and genera are discussed, and groups most in need of taxonomic and phylogenetic attention are identified. The following genera are transferred to new tribes: Acoptus LeConte, 1876 from the Lechriopini to the Othippiini (new placement and the South American genus Hedycera Pascoe, 1870 from the Lechriopini to the Piazurini (new placement. Philides Champion, 1906 and Philinna Champion, 1906 are transferred from the Lechriopini to Conoderinae incertae sedis (new placement although their placement as conoderines is uncertain. The species Copturomimus cinereus Heller, 1895 is designated as the type species of the genus Copturomimus Heller, 1895.

Regulating human genetic research in Latin America: a race to the top or a race together?

Directory of Open Access Journals (Sweden)

Rosario Isasi

2016-05-01

Full Text Available Balancing the therapeutic potential of genetic science with the adoption of policies that reflect social values has proven to be a formidable task for Latin American countries. This essay presents some reflections on human genetics research policy in Latin America and explores a path forward for policy development.

Characterization of individuals at high risk of developing melanoma in Latin America: bases for genetic counseling in melanoma.

Science.gov (United States)

Puig, Susana; Potrony, Miriam; Cuellar, Francisco; Puig-Butille, Joan Anton; Carrera, Cristina; Aguilera, Paula; Nagore, Eduardo; Garcia-Casado, Zaida; Requena, Celia; Kumar, Rajiv; Landman, Gilles; Costa Soares de Sá, Bianca; Gargantini Rezze, Gisele; Facure, Luciana; de Avila, Alexandre Leon Ribeiro; Achatz, Maria Isabel; Carraro, Dirce Maria; Duprat Neto, João Pedreira; Grazziotin, Thais C; Bonamigo, Renan R; Rey, Maria Carolina W; Balestrini, Claudia; Morales, Enrique; Molgo, Montserrat; Bakos, Renato Marchiori; Ashton-Prolla, Patricia; Giugliani, Roberto; Larre Borges, Alejandra; Barquet, Virginia; Pérez, Javiera; Martínez, Miguel; Cabo, Horacio; Cohen Sabban, Emilia; Latorre, Clara; Carlos-Ortega, Blanca; Salas-Alanis, Julio C; Gonzalez, Roger; Olazaran, Zulema; Malvehy, Josep; Badenas, Celia

2016-07-01

CDKN2A is the main high-risk melanoma-susceptibility gene, but it has been poorly assessed in Latin America. We sought to analyze CDKN2A and MC1R in patients from Latin America with familial and sporadic multiple primary melanoma (SMP) and compare the data with those for patients from Spain to establish bases for melanoma genetic counseling in Latin America. CDKN2A and MC1R were sequenced in 186 Latin American patients from Argentina, Brazil, Chile, Mexico, and Uruguay, and in 904 Spanish patients. Clinical and phenotypic data were obtained. Overall, 24 and 14% of melanoma-prone families in Latin America and Spain, respectively, had mutations in CDKN2A. Latin American families had CDKN2A mutations more frequently (P = 0.014) than Spanish ones. Of patients with SMP, 10% of those from Latin America and 8.5% of those from Spain had mutations in CDKN2A (P = 0.623). The most recurrent CDKN2A mutations were c.-34G>T and p.G101W. Latin American patients had fairer hair (P = 0.016) and skin (P < 0.001) and a higher prevalence of MC1R variants (P = 0.003) compared with Spanish patients. The inclusion criteria for genetic counseling of melanoma in Latin America may be the same criteria used in Spain, as suggested in areas with low to medium incidence, SMP with at least two melanomas, or families with at least two cases among first- or second-degree relatives.Genet Med 18 7, 727-736.

Renewable energies. A challenge and an opportunity for Central America; Energias renovables. Un reto y una oportunidad para America Central

Energy Technology Data Exchange (ETDEWEB)

Guevara, Leo; Castro S, Rene [Instituto Centroamericano de Administracion de Empresas (INCAE) (Costa Rica)

2007-07-15

There are analyzed in this working paper the following aspects: the Central America countries and their relations with the regional energy potencies -Mexico and Venezuela- and the impact they have in the energy supply. There are also explore the following aspects: the San Jose Agreement linked to the fossil fuels supply, the emerging scope boosted by Brazil and Colombia regarding to the alternative fuels. [Spanish] Este trabajo analiza los paises centroamericanos y sus relaciones con las potencias energeticas regionales como Mexico y Venezuela, y como estas impactan el suministro de energia en la region. Tambien se exploran mecanismos como el Pacto de San Jose, ligado al suministro de combustibles fosiles y las oportunidades emergentes impulsadas por Brasil y Colombia con combustibles alternativos.

SALTRA: a regional program for workers' health and sustainable development in Central America.

Science.gov (United States)

Wesseling, Catharina; Aragón, Aurora; Elgstrand, Kaj; Flores, Reinaldo; Hogstedt, Christer; Partanen, Timo

2011-01-01

In 2003, the university-based Program on Work and Health in Central America, SALTRA, was launched to build national and regional capacities in occupational safety and health with the goal of preventing and reducing poverty in Central America. SALTRA has implemented 20 projects including action projects in priority sectors (e.g., construction, sugarcane, hospitals, migrant coffee workers); strengthening of surveillance (occupational health profiles, carcinogenic exposures, fatal injuries and pesticides); a participatory model for training and risk monitoring by workers; building occupational health capacity for professionals, employers, and workers, with collaborating networks between the countries; strengthening of universities in work, environment, and health; studies of serious occupational and environmental situations; communication channels; and continued efforts to raise political awareness. SALTRA has placed issues of workers' health on political, business, and academic agendas throughout the region and has laid the foundations for achieving substantial future improvements in health conditions of all workers in the region. External evaluators envisioned SALTRA as an innovative development model.

The Development of improved willow clones for eastern North America

Science.gov (United States)

R. F. Kopp; L. B. Smart; C. A. Maynard; J. G. Isebrands; G. A. Tuskan; L. P. Abrahamson

2001-01-01

Efforts aimed at genetic improvement of Salix are increasing in North America.Most of these are directed towards developing improved clones for biomass production, phytoremediation, nutrient filters, and stream bank stabilization in the Northeast and North-central United States. Native species are of primary interest, but a small number of clones containing non-native...

Colored Height and Shaded Relief, Central America

Science.gov (United States)

2002-01-01

Panama, Costa Rica, Nicaragua, El Salvador, Honduras, Guatemala, Belize, southern Mexico and parts of Cuba and Jamaica are all seen in this image from NASA's Shuttle Radar Topography Mission. The dominant feature of the northern part of Central America is the Sierra Madre Range, spreading east from Mexico between the narrow Pacific coastal plain and the limestone lowland of the Yucatan Peninsula. Parallel hill ranges sweep across Honduras and extend south, past the Caribbean Mosquito Coast to lakes Managua and Nicaragua. The Cordillera Central rises to the south, gradually descending to Lake Gatun and the Isthmus of Panama. A highly active volcanic belt runs along the Pacific seaboard from Mexico to Costa Rica.High-quality satellite imagery of Central America has, until now, been difficult to obtain due to persistent cloud cover in this region of the world. The ability of SRTM to penetrate clouds and make three-dimensional measurements has allowed the generation of the first complete high-resolution topographic map of the entire region. This map was used to generate the image.Two visualization methods were combined to produce the image: shading and color coding of topographic height. The shade image was derived by computing topographic slope in the north-south direction. Color coding is directly related to topographic height, with green at the lower elevations, rising through yellow, red, and magenta, to white at the highest elevations.For an annotated version of this image, please select Figure 1, below: [figure removed for brevity, see original site] (Large image: 9 mB jpeg)Elevation data used in this image were acquired by the Shuttle Radar Topography Mission aboard the Space Shuttle Endeavour, launched on February 11, 2000. The mission used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar that flew twice on the Space Shuttle Endeavour in 1994. The Shuttle Radar Topography Mission was designed to collect

A review of bioinformatics training applied to research in molecular medicine, agriculture and biodiversity in Costa Rica and Central America.

Science.gov (United States)

Orozco, Allan; Morera, Jessica; Jiménez, Sergio; Boza, Ricardo

2013-09-01

Today, Bioinformatics has become a scientific discipline with great relevance for the Molecular Biosciences and for the Omics sciences in general. Although developed countries have progressed with large strides in Bioinformatics education and research, in other regions, such as Central America, the advances have occurred in a gradual way and with little support from the Academia, either at the undergraduate or graduate level. To address this problem, the University of Costa Rica's Medical School, a regional leader in Bioinformatics in Central America, has been conducting a series of Bioinformatics workshops, seminars and courses, leading to the creation of the region's first Bioinformatics Master's Degree. The recent creation of the Central American Bioinformatics Network (BioCANET), associated to the deployment of a supporting computational infrastructure (HPC Cluster) devoted to provide computing support for Molecular Biology in the region, is providing a foundational stone for the development of Bioinformatics in the area. Central American bioinformaticians have participated in the creation of as well as co-founded the Iberoamerican Bioinformatics Society (SOIBIO). In this article, we review the most recent activities in education and research in Bioinformatics from several regional institutions. These activities have resulted in further advances for Molecular Medicine, Agriculture and Biodiversity research in Costa Rica and the rest of the Central American countries. Finally, we provide summary information on the first Central America Bioinformatics International Congress, as well as the creation of the first Bioinformatics company (Indromics Bioinformatics), spin-off the Academy in Central America and the Caribbean.

A climatology of low level wind regimes over Central America using a weather type classification approach.

Directory of Open Access Journals (Sweden)

Fernán eSáenz

2015-04-01

Full Text Available Based on the potential of the weather types classification method to study synoptic features, this study proposes the application of such methodology for the identification of the main large scale patterns related with weather in Central America. Using ERA Interim low-level winds in a domain that encompasses the intra-Americas sea, the eastern tropical Pacific, southern North America, Central America and northern South America; the K-means clustering algorithm was applied to find recurrent regimes of low-level winds. Eleven regimes were identified and good coherency between the results and known features of regional circulation was found. It was determined that the main large scale patterns can be either locally forced or a response to tropical-extratropical interactions. Moreover, the local forcing dominates the summer regimes whereas mid latitude interactions lead winter regimes. The study of the relationship between the large scale patterns and regional precipitation shows that winter regimes are related with the Caribbean-Pacific precipitation seesaw. Summer regimes, on the other hand, enhance the Caribbean-Pacific precipitation contrasting distribution as a function of the dominant regimes. A strong influence of ENSO on the frequency and duration of the regimes was found. It was determined that the specific effect of ENSO on the regimes depends on whether the circulation is locally forced or lead by the interaction between the tropics and the mid-latitudes. The study of the cold surges using the information of the identified regimes revealed that three regimes are linkable with the occurrence of cold surges that affect Central America and its precipitation. As the winter regimes are largely dependent of mid-latitude interaction with the tropics, the effect that ENSO has on the Jet Stream is reflected in the winter regimes. An automated analysis of large scale conditions based on reanalysis and/or model data seems useful for both dynamical

Neoliberal Forms of Capital and The Rise of Social Movement Partyism in Central America

Directory of Open Access Journals (Sweden)

Paul Almeida

2015-08-01

Full Text Available Historical shifts in global economic formations shape the strategies of resistance movements in the global South. Neoliberal forms of economic development over the past thirty years in Central America have weakened traditional actors sponsoring popular mobilization such as labor unions and rural cooperatives. At the same time, the free market reforms produced new threats to economic livelihood and well-being throughout the region. The neoliberal measures that have generated the greatest levels of mass discontent include rising prices, privatization, labor flexibility laws, mining projects, and free trade. This article analyzes the role of emerging anti-neoliberal political parties in alliance with popular movements in Central America. Countries with already existing strong anti-systemic parties in the initial phases of the global turn to neoliberalism in the late twentieth century resulted in more efficacious manifestations of social movement partyism in the twenty-first century resisting free market globalization.

Environmental impacts during geothermal development: Some examples from Central America

International Nuclear Information System (INIS)

Goff, S.; Goff, F.

1997-01-01

The impacts of geothermal development projects are usually positive. However, without appropriate monitoring plans and mitigation actions firmly incorporated into the project planning process, there exists the potential for significant negative environmental impacts. The authors present five examples from Central America of environmental impacts associated with geothermal development activities. These brief case studies describe landslide hazards, waste brine disposal, hydrothermal explosions, and air quality issues. Improved Environmental Impact Assessments are needed to assist the developing nations of the region to judiciously address the environmental consequences associated with geothermal development

Scorpionism in Central America, with special reference to the case of Panama

Directory of Open Access Journals (Sweden)

A Borges

2012-01-01

Full Text Available Scorpionism in the Americas occurs mainly in Mexico, northern South America and southeast Brazil. This article reviews the local scorpion fauna, available health statistics, and the literature to assess scorpionism in Central America. Notwithstanding its high toxicity in Mexico, most scorpion sting cases in Guatemala, Belize, El Salvador, Nicaragua, and Costa Rica are produced by species in the genus Centruroides that are only mildly toxic to humans despite the existence of ion channel-active toxins in their venoms. Regional morbidity is low with the exception of Panama, where an incidence of 52 cases per 100,000 inhabitants was recorded for 2007, with 28 deaths from 1998 to 2006. Taxa belonging to the genus Tityus (also present in the Atlantic coast of Costa Rica are responsible for fatalities in Panama, with Tityus pachyurus being the most important species medically. Most Tityus species inhabiting Panama are also found in northern South America from which they probably migrated upon closure of the Panamanian isthmus in the Miocene era. Incorporation of Panama as part of the northern South American endemic area of scorpionism is thereby suggested based on the incidence of these accidents and the geographical distribution of Panamanian Tityus species.

Fostering regional democracy through civic organisations: comparing EU mechanisms in Europe and Central America

NARCIS (Netherlands)

Sanchez Salgado, R.; Parthenay, K.

2013-01-01

This article compares the effects of the mechanisms of the European Union (EU) on the promotion of regional civic organisations, especially funding opportunities, in two regional settings (Central America and Europe). It is argued that the EU is exporting a specific model of relationships between

A new genus and two new species of Tingidae (Heteroptera) from Central America.

Science.gov (United States)

Montemayor, Sara I

2008-04-01

A new genus, Ceratotingis, distributed in Central America, is described to accommodate two new species, C. rafaeli from Panama and C. costarriquense from Costa Rica and to include Macrotingis zeteki from Panama. This paper includes descriptions of the new genus and its species, a redescription of C. zeteki, an identification key, and habitus photographs.

The Paleo-Indian Entry into South America According to Mitogenomes.

Science.gov (United States)

Brandini, Stefania; Bergamaschi, Paola; Cerna, Marco Fernando; Gandini, Francesca; Bastaroli, Francesca; Bertolini, Emilie; Cereda, Cristina; Ferretti, Luca; Gómez-Carballa, Alberto; Battaglia, Vincenza; Salas, Antonio; Semino, Ornella; Achilli, Alessandro; Olivieri, Anna; Torroni, Antonio

2018-02-01

Recent and compelling archaeological evidence attests to human presence ∼14.5 ka at multiple sites in South America and a very early exploitation of extreme high-altitude Andean environments. Considering that, according to genetic evidence, human entry into North America from Beringia most likely occurred ∼16 ka, these archeological findings would imply an extremely rapid spread along the double continent. To shed light on this issue from a genetic perspective, we first completely sequenced 217 novel modern mitogenomes of Native American ancestry from the northwestern area of South America (Ecuador and Peru); we then evaluated them phylogenetically together with other available mitogenomes (430 samples, both modern and ancient) from the same geographic area and, finally, with all closely related mitogenomes from the entire double continent. We detected a large number (N = 48) of novel subhaplogroups, often branching into further subclades, belonging to two classes: those that arose in South America early after its peopling and those that instead originated in North or Central America and reached South America with the first settlers. Coalescence age estimates for these subhaplogroups provide time boundaries indicating that early Paleo-Indians probably moved from North America to the area corresponding to modern Ecuador and Peru over the short time frame of ∼1.5 ka comprised between 16.0 and 14.6 ka. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

[Population mobility and HIV/AIDS in Central America and Mexico].

Science.gov (United States)

Leyva-Flores, René; Aracena-Genao, Belkis; Serván-Mori, Edson

2014-09-01

Estimate the magnitude of the association between population mobility, measured by net migration rate (NMR), and HIV prevalence in Central America and Mexico. Using time series models, based on public information from UNAIDS, UNDP, ECLAC, and the World Bank for the period 1990-2009, this association was studied in individuals aged 15-49 years, and adjusted for socioeconomic factors (education, unemployment, life expectancy, and income). NMR was negative in all countries except Costa Rica and Panama. Unadjusted results of the model show a positive association and that NMR can explain 6% of recorded HIV prevalence. When socioeconomic cofactors are included by country (education, health, and income), the magnitude increases to 9% (PCentral America and Mexico, although large gaps persist among countries. The modest association observed between population mobility and HIV prevalence is conditioned by the socioeconomic status of the countries studied. Information availability limited the study's ability to establish the existence of this association with greater certainty. Accordingly, based on available information, it is not possible to affirm that migration plays a key role in the spread of HIV.

Planting the Seeds of a New Agriculture: Living with the Land in Central America.

Science.gov (United States)

Adriance, Jim

1995-01-01

Central America's macroeconomics, land tenure patterns, and population growth are forcing small-scale farmers to alternatives based on farmer-to-farmer teaching and farming in concert with the environment. Discusses major schools of thought that have fueled this phenomenon, and how extension services and isolated groups are joining to form a…

Social-group identity and population substructure in admixed populations in New Mexico and Latin America.

Directory of Open Access Journals (Sweden)

Meghan E Healy

Full Text Available We examined the relationship between continental-level genetic ancestry and racial and ethnic identity in an admixed population in New Mexico with the goal of increasing our understanding of how racial and ethnic identity influence genetic substructure in admixed populations. Our sample consists of 98 New Mexicans who self-identified as Hispanic or Latino (NM-HL and who further categorized themselves by race and ethnic subgroup membership. The genetic data consist of 270 newly-published autosomal microsatellites from the NM-HL sample and previously published data from 57 globally distributed populations, including 13 admixed samples from Central and South America. For these data, we 1 summarized the major axes of genetic variation using principal component analyses, 2 performed tests of Hardy Weinberg equilibrium, 3 compared empirical genetic ancestry distributions to those predicted under a model of admixture that lacked substructure, 4 tested the hypotheses that individuals in each sample had 100%, 0%, and the sample-mean percentage of African, European, and Native American ancestry. We found that most NM-HL identify themselves and their parents as belonging to one of two groups, conforming to a region-specific narrative that distinguishes recent immigrants from Mexico from individuals whose families have resided in New Mexico for generations and who emphasize their Spanish heritage. The "Spanish" group had significantly lower Native American ancestry and higher European ancestry than the "Mexican" group. Positive FIS values, PCA plots, and heterogeneous ancestry distributions suggest that most Central and South America admixed samples also contain substructure, and that this substructure may be related to variation in social identity. Genetic substructure appears to be common in admixed populations in the Americas and may confound attempts to identify disease-causing genes and to understand the social causes of variation in health outcomes

The burden of oesophageal cancer in Central and South America.

Science.gov (United States)

Barrios, Enrique; Sierra, Monica S; Musetti, Carina; Forman, David

2016-09-01

Oesophageal cancer shows marked geographic variations and is one of the leading causes of cancer death worldwide. We described the burden of this malignancy in Central and South America. Regional and national level incidence data were obtained from 48 population-based cancer registries in 13 countries. Mortality data were obtained from the WHO mortality database. Incidence of oesophageal cancer by histological subtype were available from high-quality population-based cancer registries. Males had higher incidence and mortality rates than females (male-to-female ratios: 2-6:1 and 2-5:1). In 2003-2007, the highest rates were in Brazil, Uruguay, Argentina and Chile. Mortality rates followed the incidence patterns. Incidence of oesophageal squamous cell carcinoma (SCC) was higher than adenocarcinoma (AC), except in females from Cuenca (Ecuador). SCC and AC incidence were higher in males than females, except in the Region of Antofagasta and Valdivia (Chile), Manizales (Colombia) and Cuenca (Ecuador). Incidence and mortality rates tended to decline in Argentina, Chile, Brazil (incidence) and Costa Rica from 1997 to 2008. The geographic variation and sex disparity in oesophageal cancer across Central and South America may reflect differences in the prevalence of tobacco smoking and alcohol consumption which highlights the need to implement and/or strengthen tobacco and alcohol control policies. Maté consumption, obesity, diet and Helicobacter pylori infection may also explain the variation in oesophageal cancer rates but these relationships should be evaluated. Continuous monitoring of oesophageal cancer rates is necessary to provide the basis for cancer prevention and control in the region. Copyright © 2015 International Agency for Research on Cancer. Published by Elsevier Ltd.. All rights reserved.

Drought assessment for cropland of Central America using course-resolution remote sensing data

Science.gov (United States)

Chen, C. F.; Nguyen, S. T.; Chen, C. R.; Chiang, S. H.; Chang, L. Y.; Khin, L. V.

2015-12-01

Drought is one of the most frequent and costliest natural disasters, which imposes enormous effects to human societies and ecosystems. Agricultural drought is referred to an interval of time, such as weeks or months, when the soil moisture supply of a region consistently falls below the appropriate moisture supply leading to negative impacts on agricultural production. Millions of households in Central America were dependent upon major food crops, including maize, beans, and sorghum, for their daily subsistence. In recent years, impacts of climate change through global warming in forms of higher temperature and widespread rainfall deficits have however triggered severe drought during the primera cropping season (April-August) in the study region, causing profound impacts on agriculture, crop production losses, increased market food prices, as well as food security issues. This study focuses on investigating agricultural droughts for cropland of Central America using the Moderate Resolution Imaging Spectroradiometer (MODIS) data. We processed the data for a normal year 2013 and an abnormal year 2014 using a simple vegetation health index (VHI) that is developed based on the temperature condition index (TCI) and vegetation condition index (VCI). The VHI results were validated using the Advanced Microwave Scanning Radiometer 2 (AMSR2) precipitation data and temperature vegetation dryness index (TVDI) that is developed based on the empirical analysis of TCI and VCI data. The correlation coefficients (r) obtained by comparisons between the VHI data and the AMSR2 precipitation and TVDI data were higher than 0.62 and -0.61, respectively. The severe drought was intensive during the dry season (January-April) and likely backed to normal conditions in May with the onset of rainy season. The larger area of serve drought was observed for the 2014 primera season, especially during April-July. When investigating the cultivated areas affected by severe drought in the primera

77 FR 15397 - Dominican Republic-Central America-United States Free Trade Agreement; Notice of Determination...

Science.gov (United States)

2012-03-15

... lack thereof denied workers their rights under the laws of the Dominican Republic relating to freedom of association, the right to organize, child labor, forced labor, the right to bargain collectively... (``submissions'') regarding labor law matters in Central America and the Dominican Republic. A Federal Register...

Radical, reformist and aborted liberalism: origins of national regimes in Central America

Directory of Open Access Journals (Sweden)

James MAHONEY

2011-06-01

Full Text Available During the twentieth century, the countries of Central America were characterized by remarkably different political regimes: military-authoritarianism in Guatemala and El Salvador, progressive democracy in Costa Rica and traditional-authoritarianism in Honduras and Nicaragua. This article explains these contrasting regime outcomes by exploring the agrarian and state-building reforms pursued by political leaders during the nineteenth– and early twentieth century liberal reform period. Based on differences in the transformation of state and class structures, three types of liberalism are identified: radical liberalism in Guatemala and El Salvador, reformist liberalism in Costa Rica and aborted liberalism in Honduras and Nicaragua. It is argued that these types of liberalism set the Central American countries on contrasting paths of political development, culminating in diverse regime outcomes.

Violence, Rule of Law, and Punitive Policies in Central America

Directory of Open Access Journals (Sweden)

Verónica De la Torre

2011-01-01

Full Text Available This article suggests that high levels of violence and crime in the so called North Triangle of Central America (Guatemala, El Salvador and Honduras, together with the incapacity of the state of enforcing the rule of law, are causing growing anxiety among the population and are attracting the support of the community to implement authoritarian measures to fight crime. The response of the governments of the region in the face of the rise of crime and public demand for security has been the policies of "iron fist", and the use of "populist punitiveness" as a strategy to gain the backing of an electorate deeply concerned by insecurity.

A key to the Mexican and Central America Genera of Anthonomini (Curculionidae, Curculioninae)

Science.gov (United States)

Hernández, Macotulio Soto; Jones, Robert W.; Castillo, Pedro Reyes

2013-01-01

Abstract Presently the only keys available for identification of genera of Anthonomini are limited to those of the United States of America and Canada. A dichotomous key is presented to identify all genera of Mexican and Central American Anthonomini. Previous keys do not include the genera Achia, Botanebius, Loncophorus, Loncophorellus and Melexerus. A brief synopsis is given for each genus and photographs of representative species are included. PMID:23717181

Forest pests in central America: Field guide. Technical manual

Energy Technology Data Exchange (ETDEWEB)

1992-01-01

In Central America, plant health problems have grown to an unprecedented level during the past few years along with the establishment of extensive homogeneous forest plantations, at times leading to the such drastic solutions as widespread felling of trees or massive use of pesticides. This field guide on forest pests was commissioned by the Multipurpose Tree Crop Dissemination (MADELENA) project and focuses on pests found in Costa Rica, home of PIROF (Programa Interinstitucional de Proteccion Forestal), a pioneer in forest pest research. The guide offers fast identification of forest pests and some general information on their biology and epidemiology. It consists of two sections: (1) lists of the specific pests (insects, vertebrates, pathogens, and parasites) of 18 priority forest tree species, and lists of the specific tree part or developmental stage they afflict.

Investigation of the nutrition problems of Central America and Panama.

Science.gov (United States)

Arroyave, Guillermo

2010-03-01

From its earliest years, INCAP gave a high priority to a multidisciplinary effort to learn as much as possible about the dietary habits, nutritional status, and their consequences in the populations of Central America and Panama. Most of the papers in this Special Issue contain some of this information. The first studies were in schoolchildren but were soon extended to preschool children, pregnant and lactating women, and other adults. This paper describes the principal findings of the initial dietary, biochemical, and clinical community-based studies. From 1965-67, very extensive studies were carried out in all six countries including dietary, biochemical, clinical, and anthological studies were carried out in all six countries, the results of which are summarized.

A spatio-temporal analysis of forest loss related to cocaine trafficking in Central America

Science.gov (United States)

Sesnie, Steven E.; Tellman, Beth; Wrathall, David; McSweeney, Kendra; Nielsen, Erik; Benessaiah, Karina; Wang, Ophelia; Rey, Luis

2017-05-01

A growing body of evidence suggests that criminal activities associated with drug trafficking networks are a progressively important driver of forest loss in Central America. However, the scale at which drug trafficking represents a driver of forest loss is not presently known. We estimated the degree to which narcotics trafficking may contribute to forest loss using an unsupervised spatial clustering of 15 spatial and temporal forest loss patch metrics developed from global forest change data. We distinguished anomalous forest loss from background loss patches for each country exhibiting potential ‘narco-capitalized’ signatures which showed a statistically significant dissimilarity from other patches in terms of size, timing, and rate of forest loss. We also compared annual anomalous forest loss with the number of cocaine shipments and volume of cocaine seized, lost, or delivered at country- and department-level. For Honduras, results from linear mixed effects models showed a highly significant relationship between anomalous forest loss and the timing of increased drug trafficking (F = 9.90, p = 0.009) that also differed significantly from temporal patterns of background forest loss (t-ratio = 2.98, p = 0.004). Other locations of high forest loss in Central America showed mixed results. The timing of increased trafficking was not significantly related to anomalous forest loss in Guatemala and Nicaragua, but significantly differed in patch size compared to background losses. We estimated that cocaine trafficking could account for between 15% and 30% of annual national forest loss in these three countries over the past decade, and 30% to 60% of loss occurred within nationally and internationally designated protected areas. Cocaine trafficking is likely to have severe and lasting consequences in terms of maintaining moist tropical forest cover in Central America. Addressing forest loss in these and other tropical locations will require a stronger

It's not too late for the harpy eagle (Harpia harpyja: high levels of genetic diversity and differentiation can fuel conservation programs.

Directory of Open Access Journals (Sweden)

Heather R L Lerner

2009-10-01

Full Text Available The harpy eagle (Harpia harpyja is the largest Neotropical bird of prey and is threatened by human persecution and habitat loss and fragmentation. Current conservation strategies include local education, captive rearing and reintroduction, and protection or creation of trans-national habitat blocks and corridors. Baseline genetic data prior to reintroduction of captive-bred stock is essential for guiding such efforts but has not been gathered previously.We assessed levels of genetic diversity, population structure and demographic history for harpy eagles using samples collected throughout a large portion of their geographic distribution in Central America (n = 32 and South America (n = 31. Based on 417 bp of mitochondrial control region sequence data, relatively high levels of haplotype and nucleotide diversity were estimated for both Central and South America, although haplotype diversity was significantly higher for South America. Historical restriction of gene flow across the Andes (i.e. between our Central and South American subgroups is supported by coalescent analyses, the haplotype network and significant F(ST values, however reciprocally monophyletic lineages do not correspond to geographical locations in maximum likelihood analyses. A sudden population expansion for South America is indicated by a mismatch distribution analysis, and further supported by significant (p<0.05 negative values of Fu and Li's D(F and F, and Fu's F(S. This expansion, estimated at approximately 60 000 years BP (99 000-36 000 years BP 95% CI, encompasses a transition from a warm and dry time period prior to 50 000 years BP to an interval of maximum precipitation (50 000-36 000 years BP. Notably, this time period precedes the climatic and habitat changes associated with the last glacial maximum. In contrast, a multimodal distribution of haplotypes was observed for Central America suggesting either population equilibrium or a recent decline.High levels of

Assessment of contemporary genetic diversity and inter-taxa/inter-region exchange of avian paramyxovirus serotype 1 in wild birds sampled in North America

Science.gov (United States)

Ramey, Andy M.; Goraichuk, Iryna V.; Hicks, Joseph T.; Dimitrov, Kiril M.; Poulson, Rebecca L.; Stallknecht, David E.; Bahl, Justin; Afonso, Claudio L.

2017-01-01

BackgroundAvian paramyxovirus serotype 1 (APMV-1) viruses are globally distributed, infect wild, peridomestic, and domestic birds, and sometimes lead to outbreaks of disease. Thus, the maintenance, evolution, and spread of APMV-1 viruses are relevant to avian health.MethodsIn this study we sequenced the fusion gene from 58 APMV-1 isolates recovered from thirteen species of wild birds sampled throughout the USA during 2007–2014. We analyzed sequence information with previously reported data in order to assess contemporary genetic diversity and inter-taxa/inter-region exchange of APMV-1 in wild birds sampled in North America.ResultsOur results suggest that wild birds maintain previously undescribed genetic diversity of APMV-1; however, such diversity is unlikely to be pathogenic to domestic poultry. Phylogenetic analyses revealed that APMV-1 diversity detected in wild birds of North America has been found in birds belonging to numerous taxonomic host orders and within hosts inhabiting multiple geographic regions suggesting some level of viral exchange. However, our results also provide statistical support for associations between phylogenetic tree topology and host taxonomic order/region of sample origin which supports restricted exchange among taxa and geographical regions of North America for some APMV-1 sub-genotypes.ConclusionsWe identify previously unrecognized genetic diversity of APMV-1 in wild birds in North America which is likely a function of continued viral evolution in reservoir hosts. We did not, however, find support for the emergence or maintenance of APMV-1 strains predicted to be pathogenic to poultry in wild birds of North America outside of the order Suliformes (i.e., cormorants). Furthermore, genetic evidence suggests that ecological drivers or other mechanisms may restrict viral exchange among taxa and regions of North America. Additional and more systematic sampling for APMV-1 in North America would likely provide further inference on viral

Medicinal plants used in the traditional management of diabetes and its sequelae in Central America: A review.

Science.gov (United States)

Giovannini, Peter; Howes, Melanie-Jayne R; Edwards, Sarah E

2016-05-26

Globally 387 million people currently have diabetes and it is projected that this condition will be the 7th leading cause of death worldwide by 2030. As of 2012, its total prevalence in Central America (8.5%) was greater than the prevalence in most Latin American countries and the population of this region widely use herbal medicine. The aim of this study is to review the medicinal plants used to treat diabetes and its sequelae in seven Central American countries: Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama. We conducted a literature review and extracted from primary sources the plant use reports in traditional remedies that matched one of the following disease categories: diabetes mellitus, kidney disease, urinary problems, skin diseases and infections, cardiovascular disease, sexual dysfunctions, visual loss, and nerve damage. Use reports were entered in a database and data were analysed in terms of the highest number of use reports for diabetes management and for the different sequelae. We also examined the scientific evidence that might support the local uses of the most reported species. Out of 535 identified species used to manage diabetes and its sequelae, 104 species are used to manage diabetes and we found in vitro and in vivo preclinical experimental evidence of hypoglycaemic effect for 16 of the 20 species reported by at least two sources. However, only seven of these species are reported in more than 3 studies: Momordica charantia L., Neurolaena lobata (L.) R. Br. ex Cass., Tecoma stans (L.) Juss. ex Kunth, Persea americana Mill., Psidium guajava L., Anacardium occidentale L. and Hamelia patens Jacq. Several of the species that are used to manage diabetes in Central America are also used to treat conditions that may arise as its consequence such as kidney disease, urinary problems and skin conditions. This review provides an overview of the medicinal plants used to manage diabetes and its sequelae in Central America and of

Drug Cartels and Gangs in Mexico and Central America: A View through the Lens of Counterinsurgency

Science.gov (United States)

2010-06-04

organization. The demise of this long–standing dynasty began after the assassination of Pedro Joaquin Chamorro, leader of the Democratic Union of Liberation...describes Mexico and all of Central America as flawed democracies with the exception of Costa Rica, which is rated as a full democracy.36 The democratic

Seismic hazard map of North and Central America and the Caribbean

Directory of Open Access Journals (Sweden)

K. M. Shedlock

1999-06-01

Full Text Available Minimization of the loss of life, property damage, and social and economic disruption due to earthquakes depends on reliable estimates of seismic hazard. National, state, and local governments, decision makers, engineers, planners, emergency response organizations, builders, universities, and the general public require seismic hazard estimates for land use planning, improved building design and construction (including adoption of building construction codes, emergency response preparedness plans, economic forecasts, housing and employment decisions, and many more types of risk mitigation. The seismic hazard map of North and Central America and the Caribbean is the concatenation of various national and regional maps, involving a suite of approaches. The combined maps and documentation provide a useful regional seismic hazard framework and serve as a resource for any national or regional agency for further detailed studies applicable to their needs. This seismic hazard map depicts Peak Ground Acceleration (PGA with a 10% chance of exceedance in 50 years. PGA, a short-period ground motion parameter that is proportional to force, is the most commonly mapped ground motion parameter because current building codes that include seismic provisions specify the horizontal force a building should be able to withstand during an earthquake. This seismic hazard map of North and Central America and the Caribbean depicts the likely level of short-period ground motion from earthquakes in a fifty-year window. Short-period ground motions effect short-period structures (e.g., one-to-two story buildings. The highest seismic hazard values in the region generally occur in areas that have been, or are likely to be, the sites of the largest plate boundary earthquakes.

Collection, Characterization and Use of Genetic Bariation in Chilean Bean Germplasm (Phaseolus vulgaris L.)

OpenAIRE

Bascur B., Gabriel; Tay U., Juan

2005-01-01

Recently performed studies on the type of seed protein present from several origins and their morphological traits have shown that the common bean (Phaseolus vulgaris L.) is native to America, being a species without a specific center of origin and with two areas of domestication: Central America and South America. In this last center, three strains were determined, one of them is called "the Chilean strain", which as noted is a sub-center of genetic diversity for this species. With the purpo...

Head and neck cancer burden and preventive measures in Central and South America.

Science.gov (United States)

Perdomo, Sandra; Martin Roa, Guillermo; Brennan, Paul; Forman, David; Sierra, Mónica S

2016-09-01

Central and South America comprise one of the areas characterized by high incidence rates for head and neck cancer. We describe the geographical and temporal trends in incidence and mortality of head and neck cancers in the Central and South American region in order to identify opportunities for intervention on the major identified risk factors: tobacco control, alcohol use and viral infections. We obtained regional- and national-level incidence data from 48 population-based cancer registries in 13 countries and cancer deaths from the WHO mortality database for 18 countries. Age-standardized incidence (ASR) and mortality (ASMR) rates per 100,000 person-years were estimated. Brazil had the highest incidence rates for oral and pharyngeal cancer in the region for both sexes, followed by Cuba, Uruguay and Argentina. Cuba had the highest incidence and mortality rates of laryngeal cancer in the region for males and females. Overall, males had rates about four times higher than those in females. Most countries in the region have implemented WHO recommendations for both tobacco and alcohol public policy control. Head and neck squamous-cell cancer (HNSCC) incidence and mortality rates in the Central and South America region vary considerably across countries, with Brazil, Cuba, French Guyana, Uruguay and Argentina experiencing the highest rates in the region. Males carry most of the HNSCC burden. Improvement and implementation of comprehensive tobacco and alcohol control policies as well as the monitoring of these factors are fundamental to prevention of head and neck cancers in the region. Copyright © 2015 International Agency for Research on Cancer. Published by Elsevier Ltd.. All rights reserved.

Evaluating Ultraviolet Radiation Exposures Determined from TOMS Satellite Data at Sites of Amphibian Declines in Central and South America

Science.gov (United States)

Middleton, Elizabeth M.; Smith, David E. (Technical Monitor)

2000-01-01

Many amphibian species have experienced substantial population declines, or have disappeared altogether, during the last several decades at a number of amphibian census sites in Central and South America. This study addresses the use of satellite-derived trends in solar ultraviolet-B (UV-B; 280-320 nm) radiation exposures at these sites over the last two decades, and is intended to demonstrate a role for satellite observations in determining whether UV-B radiation is a contributing factor in amphibian declines. UV-B radiation levels at the Earth's surface were derived from the Total Ozone Mapping Spectrometer (TOMS) satellite data, typically acquired daily since 1979. These data were used to calculate the daily erythemal (sunburning) UV-B, or UV-B(sub ery), exposures at the latitude, longitude, and elevation of each of 20 census sites. The annually averaged UV-B(sub ery) dose, as well as the maximum values, have been increasing in both Central and South America, with higher levels received at the Central American sites. The annually averaged UV-B(sub ery) exposures increased significantly from 1979-1998 at all 11 Central American sites examined (r(exp 2) = 0.60 - 0.79; P= 6750 J/sq m*d) to the annual UV-B(sub ery) total has increased from approx. 5% to approx. 15% in Central America over the 19 year period, but actual daily exposures for each species are unknown. Synergy among UV-B radiation and other factors, especially those associated with alterations of water chemistry (e.g., acidification) in aqueous habitats is discussed. These findings justify further research concerning whether UV-B(sub ery) radiation plays a role in amphibian population declines and extinctions.

Ground motion prediction models for Central America using data from 1972 to 2010

International Nuclear Information System (INIS)

Schmidt-Diaz, Victor

2014-01-01

The most important seismological aspects of Central America were reviewed. The predominant soil types and their origin were also studied. A description of the data used in aspects such as information sources, ranges of magnitude, hypocentral and epicentral distance, and earthquake classification according to their origin is presented. A procedure of soil classification for all sites is considered, based on the average spectral ratios obtained at each station, as well as in the geological maps and lithological descriptions. Attenuation equations are obtained for crustal earthquakes using data from Central America and for subduction earthquakes using records from Costa Rica. The linear functional form was used, taking the geometric mean of peak acceleration (GM PGA) or the geometric mean of the pseudo-spectral acceleration (GM PSA) obtained from the response spectra for 5% of damping, as the dependent variable. The moment magnitude, hypocentral distance, and soil type were used as independent variables. In the case of GM PSA, a total of 22 frequencies were considered. The results are compared with models proposed by other authors. In general, it is observed that values obtained in this paper are lower. The response spectra were also compared with those proposed by the Codigo Sismico de Costa Rica. For all cases, the selected least-squares one-step method is showed the highest stability of the results. (author) [es

Book review: Vetter, H. 2005. Terralog. Turtles of the World. Vol. 3. Central and South America

Directory of Open Access Journals (Sweden)

2006-12-01

Full Text Available Book review: Vetter, H. 2005. Terralog. Turtles of the World. Vol. 3. Central and South America/Schildkröten der Welt Band 3. Mittel- und Südamerika: 1-128, color pictures 606 + 9. Edition Chimaira, Frankfurt, Germany.ISBN 3-930612-82-8; 29.7 x 20.8 cm

Sovereignty under siege: drug trafficking and state capacity in the Caribbean and Central America

OpenAIRE

King, Ryan Thomas

2016-01-01

Approved for public release; distribution is unlimited Drug trafficking organizations have increased their prominence throughout the Caribbean and Central America. These organizations undermine the rule of law, increase levels of violence and corruption, and hamper development, all of which can weaken a state. Weak or failing states become domestic and regional burdens that spill over into neighboring countries and cause secondary and tertiary problems. This thesis examines causes for diff...

Gangs in Central America

National Research Council Canada - National Science Library

Ribando, Clare

2005-01-01

... activities of Central American gangs. Citizens in several Central American countries have identified crime and gang violence among the top issues of popular concern, and Honduras and El Salvador have recently enacted tough anti-gang legislation...

Genetic diversity and phylogeography of highly zoonotic Echinococcus granulosus genotype G1 in the Americas (Argentina, Brazil, Chile and Mexico) based on 8279bp of mtDNA.

Science.gov (United States)

Laurimäe, Teivi; Kinkar, Liina; Andresiuk, Vanessa; Haag, Karen Luisa; Ponce-Gordo, Francisco; Acosta-Jamett, Gerardo; Garate, Teresa; Gonzàlez, Luis Miguel; Saarma, Urmas

2016-11-01

Echinococcus granulosus is a taeniid cestode and the etiological agent of an infectious zoonotic disease known as cystic echinococcosis (CE) or hydatid disease. CE is a serious public health concern in many parts of the world, including the Americas, where it is highly endemic in many regions. Echinococcus granulosus displays high intraspecific genetic variability and is divided into multiple genotypes (G1-G8, G10) with differences in their biology and etiology. Of these, genotype G1 is responsible for the majority of human and livestock infections and has the broadest host spectrum. However, despite the high significance to the public and livestock health, the data on genetic variability and regional genetic differences of genotype G1 in America are scarce. The aim of this study was to evaluate the genetic variability and phylogeography of G1 in several countries in America by sequencing a large portion of the mitochondrial genome. We analysed 8279bp of mtDNA for 52 E. granulosus G1 samples from sheep, cattle and pigs collected in Argentina, Brazil, Chile and Mexico, covering majority of countries in the Americas where G1 has been reported. The phylogenetic network revealed 29 haplotypes and a high haplotype diversity (Hd=0.903). The absence of phylogeographic segregation between different regions in America suggests the importance of animal transportation in shaping the genetic structure of E. granulosus G1. In addition, our study revealed many highly divergent haplotypes, indicating a long and complex evolutionary history of E. granulosus G1 in the Americas. Copyright © 2016 Elsevier B.V. All rights reserved.

Correlation of proterozoic sediments of Western and Central Africa and South America based upon radiochronological and paleontological data

International Nuclear Information System (INIS)

Bonhomme, M.G.

1982-01-01

Nearly 70 new Rb-Sr isochron ages and many K-Ar conventional ages have been determined between 1975 and 1980 on Proterozoic sedimentary or metasedimentary sequences in western and Central Africa and South America. Some stratigraphic results have been established: (1) five formations have been dated of the Lower Proterozoic; (2) a long sedimentation gap occurs, mainly in western Africa and in some regions of Central Africa and South America between nearly 1600 and 1100 Ma; (3) the upper Riphean assemblages of stromatolites have been dated and compared to those of the Eurasian craton; (4) two main glacial events have been dated, the first one placed at ca. 950 Ma, the second during the Vendian, at ca. 650-620 Ma; (5) it can be stated that, when applied to Precambrian sequences, all stratigraphic methods must be used together. (Auth.)

Exploration of a rare population of Chinese chestnut in North America: stand dynamics, health and genetic relationships.

Science.gov (United States)

Miller, Amy C; Woeste, Keith E; Anagnostakis, Sandra L; Jacobs, Douglass F

2014-10-20

With the transport of plants around the globe, exotic species can readily spread disease to their native relatives; however, they can also provide genetic resistance to those relatives through hybrid breeding programmes. American chestnut (Castanea dentata) was an abundant tree species in North America until its decimation by introduced chestnut blight. To restore chestnut in North America, efforts are ongoing to test putative blight-resistant hybrids of Castanea dentata and Chinese chestnut (Castanea mollissima), but little is known about the ecology of C. mollissima. In a forest in northeastern USA in which C. mollissima has become established, we explored questions of stand dynamics, health and genetic relationships of C. mollissima offspring to an adjacent parent orchard. We found that C. mollissima was adapted and randomly distributed among native species in this relatively young forest. The genetics of the C. mollissima population compared with its parents indicated little effect of selection pressure as each of the parent trees contributed at least one offspring. The ease with which this exotic species proliferated calls to question why C. mollissima is rare elsewhere in forests of North America. It is likely that a time window of low animal predation allowed seedlings to establish, and the shallow soil at this site limited the maximum forest canopy height, permitting the characteristically short-statured C. mollissima to avoid suppression. Our results indicate that because C. mollissima exhibited pioneer species characteristics, hybrids between C. mollissima and C. dentata have the potential to be successful pioneer species of future forests in North America, and we challenge the paradigm that exotic tree species are wholly detrimental to native biodiversity. We contend that exotic tree species should be assessed not only by their level of threat to native species, but also by their potential positive impacts on ecosystems via hybrid breeding programmes

Reproductive performance of dairy cattle in Latin America

International Nuclear Information System (INIS)

Taylor, R.T.; Barnabe, R.C.; Morales, J.R.

1990-01-01

The review describes the commonly practised systems of milk production in sample countries within the five major topographical/climatological subregions of Latin America, viz. Central America, the Caribbean, the South American subtropics, the Andes and the Temperate Zone. The state of development and importance of the dairy industry to the economy of each country are discussed. Production and reproduction indices are quoted, as are the genetic make-up of the dairy herds, husbandry practices and the quality of livestock management. It is clear that there is an enormous capacity for improvement in the efficiency of milk production systems in the Latin American region as a whole; to achieve this improvement, there is an urgent need to pursue on-farm based research aimed at identifying constraints to the performance of dairy cattle and the implementation of low cost management/nutritional/health control measures. (author)

Interplate coupling along segments of the Central America Subduction zone

Science.gov (United States)

Zarifi, Zoya; Raeesi, Mohammad; Atakan, Kuvvet

2013-04-01

We analyzed 5 major earthquakes that occurred during 1992 to 2012 in a segment of the Central America subduction zone along the coasts of Guatemala and El Salvador. These events include 1992/09/02 (Mw 7.7), 1993/09/10 (Mw 7.2), 2001/01/13 (Mw 7.7), 2012/08/27 (Mw 7.3) and 2012/11/07 (Mw 7.3). We derived the asperities of these earthquakes using two completely independent methods of body-waveform inversion and a gravity-derived measure, Trench Parallel Bouguer Anomaly (TPBA). Using TPBA we discuss the status of interplate coupling along the segment and interpret each of the major earthquakes as a piece of the governing rupture process. We delineate the critical unbroken asperities along the segment that will likely generate great earthquake(s) in the future.

Genetic Differentiation within the Puccinia triticina Population in South America and Comparison with the North American Population Suggests Common Ancestry and Intercontinental Migration

Science.gov (United States)

Leaf rust, caused by Puccinia triticina is the most prevalent and widespread disease of wheat in South America. The objective of this study was to determine the number of genetically differentiated groups of P. triticina that are currently present in South America, and to compare the South American ...

Accelerated Evolution and Functional Divergence of the Dim Light Visual Pigment Accompanies Cichlid Colonization of Central America.

Science.gov (United States)

Hauser, Frances E; Ilves, Katriina L; Schott, Ryan K; Castiglione, Gianni M; López-Fernández, Hernán; Chang, Belinda S W

2017-10-01

Cichlids encompass one of the most diverse groups of fishes in South and Central America, and show extensive variation in life history, morphology, and colouration. While studies of visual system evolution in cichlids have focussed largely on the African rift lake species flocks, Neotropical cichlids offer a unique opportunity to investigate visual system evolution at broader temporal and geographic scales. South American cichlid colonization of Central America has likely promoted accelerated rates of morphological evolution in Central American lineages as they encountered reduced competition, renewed ecological opportunity, and novel aquatic habitats. To investigate whether such transitions have influenced molecular evolution of vision in Central American cichlids, we sequenced the dim-light rhodopsin gene in 101 Neotropical cichlid species, spanning the diversity of the clade. We find strong evidence for increased rates of evolution in Central American cichlid rhodopsin relative to South American lineages, and identify several sites under positive selection in rhodopsin that likely contribute to adaptation to different photic environments. We expressed a Neotropical cichlid rhodopsin protein invitro for the first time, and found that while its spectral tuning properties were characteristic of typical vertebrate rhodopsin pigments, the rate of decay of its active signalling form was much slower, consistent with dim light adaptation in other vertebrate rhodopsins. Using site-directed mutagenesis combined with spectroscopic assays, we found that a key amino acid substitution present in some Central American cichlids accelerates the rate of decay of active rhodopsin, which may mediate adaptation to clear water habitats. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Soil conservation in Central America and Panama: current problems.

Science.gov (United States)

Popenoe, H

1976-06-01

Soil conservation measures in Central America go back to the Maya civilization, in which terracing was employed. After the Spanish conquest, plowing, livestock raising, and the succession of social and political changes all contributed to accelerate erosion. Through the past few decades, awareness of the need for soil conservation has again increased; El Salvador and Costa Rica began efforts in that direction in 1943. For sometime, the use of machinery and chemical fertilizers has masked the loss of topsoil, but under recent increases in population pressures, soil conservation measures are gaining in importance. Important agents of erosion in the tropics are heavy seasonal rains at high elevations, alternating with long dry seasons; wind erosion; and landslides after saturation of the soil during prolonged rains. Modern machinery often hastens soil removal, as do also overgrazing, deforestation and vertical crop rows. Under the present energy crisis, human labor is becoming again a significant element in crop production, and soil conservation becomes thereby more feasible and more important.

The multiple genetic causes of central hypothyroidism.

Science.gov (United States)

Persani, Luca; Bonomi, Marco

2017-03-01

An insufficient stimulation by thyrotropin (TSH) of an otherwise normal thyroid gland represents the cause of Central Hypothyrodism (CeH). CeH is about 1000-folds rarer than Primary Hypothyroidism and often represents a real challenge for the clinicians, mainly because they cannot rely on adequately sensitive parameters for diagnosis or management, as it occurs with circulating TSH in PH. Therefore, CeH diagnosis can be frequently missed or delayed in patients with a previously unknown pituitary involvement. A series of genetic defects have been described to account for isolated CeH or combined pituitary hormone defects (CPHDs) with variable clinical characteristics and degrees of severity. The recently identified candidate gene IGSF1 appears frequently involved. This review provides an updated illustration of the different genetic defects accounting for CeH. Copyright © 2017 Elsevier Ltd. All rights reserved.

Managing weather and climate risks to agriculture in North America, Central America and the Caribbean

Directory of Open Access Journals (Sweden)

Harlan D. Shannon

2015-12-01

Full Text Available In recent decades, numerous weather- and climate-related natural disasters have impacted North America, Central America, and the Caribbean, repeatedly demonstrating how vulnerable local agriculture is to extreme episodic events. Given this recent history, and expectations that the frequency and intensity of some episodic events will increase with climate change, it is becoming increasingly important for farmers to proactively manage weather and climate risks to agriculture to protect their livelihoods. Some farmers in this region already apply various strategies to help reduce weather and climate risks and uncertainties, including farming in multiple locations, diversifying crops and varieties, seeking alternative sources of income, and purchasing crop insurance. Such efforts often help farmers maintain a more stable income while also protecting and preserving the productivity of the land. Other farmers, however, have failed to implement basic risk management strategies despite the clear benefits. Reasons for these failures can be attributed to inadequate farmer education and training, a lack of tools to help facilitate the practical application of risk management concepts, and poor communications between the agrometeorological and farming communities. The agrometeorological community can help overcome these obstacles by building upon existing efforts that have successfully educated farmers about weather and climate risks to agriculture and have equipped farmers with the data, tools, and applications necessary to manage these risks. Farmer input is critical to preparing effective educational and training materials and developing user-friendly risk management tools. The agrometeorological community should solicit input from farmers regularly to ensure that farmers are obtaining the information necessary to effectively manage weather and climate risks to agriculture.

First discovery of Quercus feeding Nepticulidae (Lepidoptera) in Central America.

Science.gov (United States)

Stonis, Jonas R; Diškus, Arūnas; Remeikis, Andrius; Schuster, Jack

2013-11-18

Despite the high taxonomic diversity of oaks in Mexico and Central America, no Quercus feeding Nepticulidae have ever been recorded from the region. Here, we present seven species whose larvae are leaf-miners of Quercus (section Lobatae) in Guatemala. Except Stigmella nigriverticella (Chambers 1875), which was previously known from the United States, all other discovered species are new. We describe and name five new species (Stigmella jaguari Remeikis & Stonis, sp. nov., S. lauta Diškus & Stonis, sp. nov., S. sublauta Remeikis & Stonis, sp. nov., S. aurifasciata Diškus & Stonis, sp. nov. and S. guatemalensis Diškus & Stonis, sp. nov.); the remaining new species is described but left unnamed because of lack of adults (i. e. moths and genitalia are described from developed pupae). All seven treated species are illustrated with photographs of the leaf-mines, adults, and genitalia.

Peripartum Cardiomyopathy: Moving Towards a More Central Role of Genetics#

Science.gov (United States)

Cemin, Roberto; Janardhanan, Rajesh; Donazzan, Luca; Daves, Massimo

2013-01-01

Peripartum cardiomyopathy (PCM) is a relatively rare disease with potentially devasting consequences requiring prompt identification and correct treatment. Overall prognosis is good in majority of the cases, although some patients may progress to irreversible heart failure. Early diagnosis is important and effective treatment reduces mortality rates and increases the chance of complete recovery of ventricular systolic function. The aetiology and pathogenesis seems to be multifactorial and poorly understood, with the available literature rather conflicting. In recent years, there has been increased interest in the role played by genetic predisposition in the development of PCM. It probably develops as a result of a complex interaction of pregnancy-associated factors and genetic factors and recently there have been many observations pointing out the central role played by a genetic predisposition. The direct and indirect observations on genetic susceptibility may offer new insights into the pathogenesis of PCM. However, larger studies are needed before advising routine genetic testing in these patients. PMID:23909634

Korean Investments in Latin America: Current Status and Prospects

Directory of Open Access Journals (Sweden)

Taik-Hwan Jyoung

1998-06-01

Full Text Available This thesis first took an overall look at the relationship between Asia and Central and South America. Meanwhile, this thesis studied the growth potential of these two continents and the rapid growth trend compared with other areas. Based on these, this thesis emphasized the necessity of the cooperation between Asia and Central and South America, which has been alienated for a long period. Upon studying of this thesis, the reader will track the connection of the overseas investment strategy of Korea to the domestic and overseas economic factors while analyzing its motivation and feature, etc. Also, it analyzes Korea's future investment in Central and South America as comparing with the strategies of Japan and Taiwan. Besides, in this thesis the author is trying to get future-oriented experiences from the analyses in areas such as trade, investment experience, culture difference and personnel exchange, and the prospect of the relationship between Korea and Central and South America. This thesis brought forward the 'blueprint' about promoting the cooperation between Asia and Central and South America, such as to organize the meeting for the new setting summit conference of Asian and Central American leaders, to add members from Central and South America countries to the MERCOSUR of APEC, to expand items in order to promote mutual-communication.

Data on medicinal plants used in Central America to manage diabetes and its sequelae (skin conditions, cardiovascular disease, kidney disease, urinary problems and vision loss

Directory of Open Access Journals (Sweden)

Peter Giovannini

2016-06-01

Full Text Available The data described in this article is related to the review article “Medicinal plants used in the traditional management of diabetes and its sequelae in Central America: a review” (Giovannini et al., 2016 [1]. We searched publications on the useful plants of Central America in databases and journals by using selected relevant keywords. We then extracted reported uses of medicinal plants within the disease categories: diabetes mellitus, kidney disease, urinary problems, skin diseases and infections, cardiovascular disease, sexual dysfunction, vision loss, and nerve damage. The following countries were included in our definition of Central America: Belize, Guatemala, Honduras, El Salvador, Nicaragua, Costa Rica and Panama. Data were compiled in a bespoke Access database. Plant names from the published sources were validated against The Plant List (TPL, (The Plant List, 2013 [2] and accepted names and synonyms were extracted. In total, the database includes 607 plant names obtained from the published sources which correspond to 537 plant taxa, 9271 synonyms and 1055 use reports.

The genetics of shovel shape in maxillary central incisors in man.

Science.gov (United States)

Blanco, R; Chakraborty, R

1976-03-01

From dental casts of 94 parent-offspring and 127 full-sib pairs, sampled from two Chilean populations, shovelling indices are computed to measure the degree of shovelling of maxillary central incisors quantitatively. Genetic correlations are computed to determine the role of genetic factors in explaining the variation in this trait. Assuming only hereditary factors to be responsible for the transmission of shovel shape, 68% of total variability is ascribed to the additive effect of genes.

Multi-year GNSS monitoring of atmospheric IWV over Central and South America for climate studies

Science.gov (United States)

Mendoza, Luciano; Bianchi, Clara; Fernández, Laura; Natali, María Paula; Meza, Amalia; Moirano, Juan

2017-04-01

Atmospheric water vapour has been acknowledged as an essential climate variable. Weather prediction and hazard assessment systems benefit from real-time observations, whereas long-term records contribute to climate studies. Nowadays, ground-based GNSS products have become widely employed, complementing satellite observations over the oceans. Although the past decade has seen a significant development of the GNSS infrastructure in Central and South America, its potential for atmospheric water vapour monitoring has not been fully exploited. With this in mind, we have performed a regional, seven-year long and homogeneous analysis, comprising 136 GNSS tracking stations, obtaining high-rate and continuous observations of column integrated water vapour and troposphere zenith total delay (Bianchi et al. 2016). As preliminary application for this data set, we have estimated local water vapour trends, their significance, and their relation with specific climate regimes. We have found evidence of drying at temperate regions in South America, at a rate of about 2% per decade, while a slow moistening of the troposphere over tropical regions is also weakly suggested by our results. Furthermore, we have assessed the regional performance of the empirical model GPT2w to blindly estimate troposphere delays. The model fairly reproduces the observed mean delays, including their annual and semi-annual variations. Nevertheless, a long-term evaluation has shown systematical biases, up to 20 mm, probably inherited form the underling atmospheric reanalysis. Additionally, the complete data set has been made openly available at a scientific repository (doi:10.1594/PANGAEA.858234). References: C. Bianchi, L. Mendoza, L. Fernandez, M. P. Natali, A. Meza, J. F. Moirano, Multi-year GNSS monitoring of atmospheric IWV over Central and South America for climate studies, Ann. Geophys., ISSN 0992-7689, eISSN 1432-0576, 34 (7), 623-639 (doi:10.5194/angeo-34-623-2016).

Linking National Parks with its Gateway Communities for Tourism Development in Central America: Nindiri, Nicaragua, Bagazit, Costa Rica and Portobelo, Panama

Directory of Open Access Journals (Sweden)

Aguirre G., J. A.

2006-01-01

Full Text Available Protected areas and national parks are becoming one of the most important forms of land use in Central America. All the projections made by the World Tourism Organization seems to agree that by 2010 Central America, maybe receiving between eight and ten millions tourists, a figure that is almost twice what the region is receiving today. A study was conducted base on 369 direct field surveys conducted in three Central American communities: Bagazit gateway community to Palo Verde National Park, Costa Rica, Nindiri, gateway community to Volcan Masaya National Park, Nicaragua and Portobelo, gateway community to Por-tobelo National Park, Panama. The study found that relative to the socio-demographic variables, that there were no significance differences at the 95% probability level in all four variables, age, sex, education and monthly income of the family. Educational level seems to be the socio-demographic variables affecting more the state of relations. The perception variable being has taken into account in the decision that affects the communities and responsibility to help with community problems are present in two of the three models. The perception variables related to tourism, feel trained to take care of the tourist and existence of businesses that can caters to tourist seem to be key elements in the community perception about the state of relation. Tourism related economic activities and community participation in park decisions are today and will be in the future essential elements in the shaping of community/park relations in Central America as tourism becomes a major economic sector in the region economy.

Spread of butternut canker in North America, host range, evidence of resistance within butternut populations and conservation genetics

Science.gov (United States)

M. E. Ostry; K. Woeste

2004-01-01

Butternut canker is killing trees throughout the range of butternut in North America and is threatening the viability of many populations in several areas. Although butternut is the primary host, other Juglans species and some hardwood species also are potential hosts. Evidence is building that genetic resistance within butternut populations may be...

Active strike-slip faulting in El Salvador, Central America

Science.gov (United States)

Corti, Giacomo; Carminati, Eugenio; Mazzarini, Francesco; Oziel Garcia, Marvyn

2005-12-01

Several major earthquakes have affected El Salvador, Central America, during the Past 100 yr as a consequence of oblique subduction of the Cocos plate under the Caribbean plate, which is partitioned between trench-orthogonal compression and strike-slip deformation parallel to the volcanic arc. Focal mechanisms and the distribution of the most destructive earthquakes, together with geomorphologic evidence, suggest that this transcurrent component of motion may be accommodated by a major strike-slip fault (El Salvador fault zone). We present field geological, structural, and geomorphological data collected in central El Salvador that allow the constraint of the kinematics and the Quaternary activity of this major seismogenic strike-slip fault system. Data suggest that the El Salvador fault zone consists of at least two main ˜E-W fault segments (San Vicente and Berlin segments), with associated secondary synthetic (WNW-ESE) and antithetic (NNW-SSE) Riedel shears and NW-SE tensional structures. The two main fault segments overlap in a dextral en echelon style with the formation of an intervening pull-apart basin. Our original geological and geomorphologic data suggest a late Pleistocene Holocene slip rate of ˜11 mm/yr along the Berlin segment, in contrast with low historical seismicity. The kinematics and rates of deformation suggested by our new data are consistent with models involving slip partitioning during oblique subduction, and support the notion that a trench-parallel component of motion between the Caribbean and Cocos plates is concentrated along E-W dextral strike-slip faults parallel to the volcanic arc.

The Previously Undetected Presence of Culex restuans (Diptera: Culicidae) in Central America, with Notes on Identification

Science.gov (United States)

1988-01-01

geografica actualizada. Rev. Inv. Salud Publica (Mexico) 33: 11 I - 125. Heinemann, S.J. and J.N. Belkin. 1977. Collection records of the project...Mosquitoes of Middle America” 8. Central America: Belize (BH), Guatemala (GUA), El Salvador ( SAL ), Honduras (HON), Nicaragua (NI, NIC). Mosq. Syst...Culicidae). Ill. Nat. Hist. Surv. Biol. Notes 52, 50 pp. Vargas, L. 1956. Especies y distribucidn de mosquitos mexicanos no anofelinos. Rev. Instit. de

A new species of the genus Mahanarva Distant, 1909 (Hemiptera: Cercopoidea: Cercopidae, with a key to the species from Central America and Mexico

Directory of Open Access Journals (Sweden)

Ulises Castro–Valderrama

2018-02-01

Full Text Available The genus Mahanarva Distant, 1909 (Hemiptera: Cercopoidea: Cercopidae currently includes two subgenera: Mahanarva Distant, 1909 with 38 species and six subspecies, and Ipiranga Fennah, 1968 with nine species. The Manaharva species are all from the Americas, and a few species are important pests in pasture grasses and sugarcane. There are no reports of any Manaharva species from North America, including Mexico and areas to the north. Here, a new species is described from Mexico and a key to the species of Mahanarva from Central America and Mexico is proposed.

Cenozoic biogeography and evolution in direct-developing frogs of Central America (Leptodactylidae: Eleutherodactylus) as inferred from a phylogenetic analysis of nuclear and mitochondrial genes.

Science.gov (United States)

Crawford, Andrew J; Smith, Eric N

2005-06-01

We report the first phylogenetic analysis of DNA sequence data for the Central American component of the genus Eleutherodactylus (Anura: Leptodactylidae: Eleutherodactylinae), one of the most ubiquitous, diverse, and abundant components of the Neotropical amphibian fauna. We obtained DNA sequence data from 55 specimens representing 45 species. Sampling was focused on Central America, but also included Bolivia, Brazil, Jamaica, and the USA. We sequenced 1460 contiguous base pairs (bp) of the mitochondrial genome containing ND2 and five neighboring tRNA genes, plus 1300 bp of the c-myc nuclear gene. The resulting phylogenetic inferences were broadly concordant between data sets and among analytical methods. The subgenus Craugastor is monophyletic and its initial radiation was potentially rapid and adaptive. Within Craugastor, the earliest splits separate three northern Central American species groups, milesi, augusti, and alfredi, from a clade comprising the rest of Craugastor. Within the latter clade, the rhodopis group as formerly recognized comprises three deeply divergent clades that do not form a monophyletic group; we therefore restrict the content of the rhodopis group to one of two northern clades, and use new names for the other northern (mexicanus group) and one southern clade (bransfordii group). The new rhodopis and bransfordii groups together form the sister taxon to a clade comprising the biporcatus, fitzingeri, mexicanus, and rugulosus groups. We used a Bayesian MCMC approach together with geological and biogeographic assumptions to estimate divergence times from the combined DNA sequence data. Our results corroborated three independent dispersal events for the origins of Central American Eleutherodactylus: (1) an ancestor of Craugastor entered northern Central America from South American in the early Paleocene, (2) an ancestor of the subgenus Syrrhophus entered northern Central America from the Caribbean at the end of the Eocene, and (3) a wave of

Do pathogens become more virulent as they spread? Evidence from the amphibian declines in Central America.

Science.gov (United States)

Phillips, Ben L; Puschendorf, Robert

2013-09-07

The virulence of a pathogen can vary strongly through time. While cyclical variation in virulence is regularly observed, directional shifts in virulence are less commonly observed and are typically associated with decreasing virulence of biological control agents through coevolution. It is increasingly appreciated, however, that spatial effects can lead to evolutionary trajectories that differ from standard expectations. One such possibility is that, as a pathogen spreads through a naive host population, its virulence increases on the invasion front. In Central America, there is compelling evidence for the recent spread of pathogenic Batrachochytrium dendrobatidis (Bd) and for its strong impact on amphibian populations. Here, we re-examine data on Bd prevalence and amphibian population decline across 13 sites from southern Mexico through Central America, and show that, in the initial phases of the Bd invasion, amphibian population decline lagged approximately 9 years behind the arrival of the pathogen, but that this lag diminished markedly over time. In total, our analysis suggests an increase in Bd virulence as it spread southwards, a pattern consistent with rapid evolution of increased virulence on Bd's invading front. The impact of Bd on amphibians might therefore be driven by rapid evolution in addition to more proximate environmental drivers.

What caused the cool summer over northern Central Asia, East Asia and central North America during 2009?

International Nuclear Information System (INIS)

Ha, Kyung-Ja; Chu, Jung-Eun; Lee, June-Yi; Wang, Bin; Hameed, Saji N; Watanabe, Masahiro

2012-01-01

Cool and wet weather conditions hit northern Central Asia, East Asia and central North America during the 2009 summer in concert with a strong jet stream and a prominent meandering upper-level circulation in the Northern Hemisphere mid-latitudes despite the fact that the year 2009 is the fifth warmest year globally in the modern record. It is found that the conspicuous atmospheric variability in the entire Northern Hemisphere mid-latitudes during the summer of 2009 was caused by a combination of teleconnections associated with significant tropical thermal forcings, strong polar forcing, and interaction between high-frequency weather events and climate anomalies. The strong negative circumglobal teleconnection pattern associated with the deficient Indian summer monsoon rainfall and developing El Niño condition was the major contributor to the cool and wet summer in June. On the other hand, the July weather conditions were attributable to the high-latitude impact of the unprecedented negative Arctic Oscillation, together with the Rossby wave response to the subtropical heating generated by convective activities over the Western North Pacific summer monsoon region. It is also noted that enhanced storm track activity and frequent cold surges from high-latitudes may have played a role in the cool and wet summer over the regions of interest. (letter)

Anxiety and depression during pregnancy in Central America : a cross-sectional study among pregnant women in the developing country Nicaragua

NARCIS (Netherlands)

Verbeek, T.; Arjadi, R.; Vendrik, J. J.; Burger, H.; Berger, M. Y.

2015-01-01

Background: Around the world, maternal psychopathology during pregnancy is associated with a range of negative consequences for mother and child. Nevertheless, in Central America the magnitude of this public health problem is still unknown. The objective of this first explorative study was to

Genetic structure of the tiger mosquito, Aedes albopictus, in Cameroon (Central Africa.

Directory of Open Access Journals (Sweden)

Basile Kamgang

Full Text Available Aedes albopictus (Skuse, 1884 (Diptera: Culicidae, a mosquito native to Asia, has recently invaded all five continents. In Central Africa it was first reported in the early 2000s, and has since been implicated in the emergence of arboviruses such as dengue and chikungunya in this region. Recent genetic studies of invasive species have shown that multiple introductions are a key factor for successful expansion in new areas. As a result, phenotypic characters such as vector competence and insecticide susceptibility may vary within invasive pest species, potentially affecting vector efficiency and pest management. Here we assessed the genetic variability and population genetics of Ae. albopictus isolates in Cameroon (Central Africa, thereby deducing their likely geographic origin.Mosquitoes were sampled in 2007 in 12 localities in southern Cameroon and analyzed for polymorphism at six microsatellite loci and in two mitochondrial DNA regions (ND5 and COI. All the microsatellite markers were successfully amplified and were polymorphic, showing moderate genetic structureamong geographic populations (F(ST  = 0.068, P < 0.0001. Analysis of mtDNA sequences revealed four haplotypes each for the COI and ND5 genes, with a dominant haplotype shared by all Cameroonian samples. The weak genetic variation estimated from the mtDNA genes is consistent with the recent arrival of Ae. albopictus in Cameroon. Phylogeographic analysis based on COI polymorphism indicated that Ae. albopictus populations from Cameroon are related to tropical rather than temperate or subtropical outgroups.The moderate genetic diversity observed among Cameroonian Ae. albopictus isolates is in keeping with recent introduction and spread in this country. The genetic structure of natural populations points to multiple introductions from tropical regions.

Post-War Central America

Directory of Open Access Journals (Sweden)

Dirk Kruijt

2003-10-01

Full Text Available – Terror in the Countryside. Campesino Responses to Political Violence in Guatemala, 1954-1985, by Rachel A. May. Athens, Ohio: Ohio University Center for International Studies/Research in International Studies/Latin America Series #35, 2001. – La guerrilla fue mi camino. Epitafio para César Montes, by Julio César Macías. Guatemala: Piedra Santa/Colección Afluentes de Modernidad, 1999. – Testigo de conciencia (Periodismo de Opinión Documentado, by Marco A. Mérida. Guatemala: ARCASAVI, 2000. – Centroamérica 2002. Un nuevo modelo de desarrollo regional, edited by Klaus Bodemer and Eduardo Gamarra. Caracas: Nueva Sociedad, 2002. – Who Governs? Guatemala Five years After the Peace Accords, by Rachel Sieder, Megan Thomas, George Vickers and Jack Spence. Cambridge, Mass.: Hemispheric Initiatives/Washington Office on Latin America (WOLA, January 2002. – Pasos hacia una nueva convivencia: Democracia y participación en Centroamérica, edited by Ricardo Córdova Macías, Günther Maihold and Sabina Kurtenbach. San Salvador: FUNDAUNGO, Instituto de Estudios Iberoamericanos de Hamburgo and Instituto Iberoamericano de Berlin, 2001. – Los desafíos de la democracia en Centroamérica, by René Poitevin and Alexander Sequén-Mónchez. Guatemala: FLACSO, 2002. – Más allá de las elecciones: Diez años después de los acuerdos de paz, edited by Hector Dada Hirezi. San Salvador: FLACSO, 2002. – Guatemala, un proyecto inconcluso: La multiculturalidad, un paso hacia la democracia, by Hugo Cayzac. Guatemala: FLACSO, 2001. – La violencia en el contexto del posconflicto, según la percepción de comunidades urbanas pobres de Guatemala, by Caroline Moser and Cathy McIlwaine. Washington/Bogotá: Banco Mundial-Región de Latinoamérica y el Caribe/Tercer Mundo Editores, 2001. – El lado oscuro de la eterna primavera. Violencia, criminalidad y delincuencia en la postguerra, by Manolo Vela, Alexander Sequén-Mónchez and Hugo Antonio Solares

The social perspective of desertification: Analysis of the public administration perception in Central America

International Nuclear Information System (INIS)

Garay Romero, Ingrid Carolina; Cabero Dieguez, Valentin

2013-01-01

Desertification is a complex problem and not only represents terrestrial ecosystems degradation. Today, it is well known that this process is linked to environmental deterioration as well as to economic and social factors, producing relevant impact in food security, poverty, migration and imbalance in many countries. Desertification perception analysis is essential in the design of the policies to fight this problem. Perception analysis in Central America is a very controversial issue and should be part of administration instruments and application strategies such as international agreements that will be included in public policies of the different States.

Warm and Dry Spells (WDS in Austral Winter over Central South America

Directory of Open Access Journals (Sweden)

P. Satyamurty

2007-06-01

Full Text Available The horizontal and vertical structure of unusually warm and dry spells (WDS over the central parts of South America during the winter and post-winter months (JJAS are studied. During WDS the mean temperature and humidity anomalies over central Brazil are about +4.1°C and −13.2%, respectively. The mean duration of WDS is 11 days and their mean frequency is less than one per year during the months of JJAS. Apparently, WDS have no preference for the phase of ENSO. Widespread and persistent subsidence in the middle troposphere is observed in tropical Brazil during WDS, which renders the lower tropospheric air warm and dry. The negative anomalies of the specific humidity are observed to be associated with the subsidence regions. A strong, slow moving ridge in the eastern South Pacific and a low-pressure center in northern Argentina are important surface characteristics during the WDS. A more detailed investigation of two specific WDS events, a strong event (August–September 1999 and a moderate one (June 2002, shows a blocking-like situation in the 500-hPa geopotential and surface pressure fields in the Pacific. The South Atlantic subtropical high somewhat approaches the continent. Strong northerlies over the central and eastern parts of Brazil are also observed in the lower troposphere. During WDS the regional circulation acquires summertime characteristics, except for the absence of precipitation, and the circulation in the meridional plane is in the opposite sense from the Hadley circulation. A frontal system, supported by a 500-hPa trough, advances into central Brazil, causing the dissipation of the anomalous situation.

HPV16 genetic variation and the development of cervical cancer worldwide

Science.gov (United States)

Cornet, I; Gheit, T; Iannacone, M R; Vignat, J; Sylla, B S; Del Mistro, A; Franceschi, S; Tommasino, M; Clifford, G M

2013-01-01

Background: Factors that favour a small proportion of HPV16 infections to progress to cancer are still poorly understood, but several studies have implicated a role of HPV16 genetic variation. Methods: To evaluate the association between HPV16 genetic variants and cervical cancer risk, we designed a multicentre case–control study based on HPV16-positive cervical samples (1121 cervical cancer cases and 400 controls) from the International Agency for Research on Cancer biobank. By sequencing the E6 gene, HPV16 isolates were classified into variant lineages and the European (EUR)-lineage isolates were subclassified by the common polymorphism T350G. Results: Incidence of variant lineages differed between cases and controls in Europe/Central Asia (P=0.006, driven by an underrepresentation of African lineages in cases), and South/Central America (P=0.056, driven by an overrepresentation of Asian American/North American lineages in cases). EUR-350G isolates were significantly underrepresented in cervical cancer in East Asia (odds ratio (OR)=0.02 vs EUR-350T; 95% confidence interval (CI)=0.00–0.37) and Europe/Central Asia (OR=0.42; 95% CI=0.27–0.64), whereas the opposite was true in South/Central America (OR=4.69; 95% CI=2.07–10.66). Conclusion: We observed that the distribution of HPV16 variants worldwide, and their relative risks for cervical cancer appear to be population-dependent. PMID:23169278

Conservation biogeography of red oaks (Quercus, section Lobatae) in Mexico and Central America.

Science.gov (United States)

Torres-Miranda, Andrés; Luna-Vega, Isolda; Oyama, Ken

2011-02-01

Oaks are dominant trees and key species in many temperate and subtropical forests in the world. In this study, we analyzed patterns of distribution of red oaks (Quercus, section Lobatae) occurring in Mexico and Central America to determine areas of species richness and endemism to propose areas of conservation. Patterns of richness and endemism of 75 red oak species were analyzed using three different units. Two complementarity algorithms based on species richness and three algorithms based on species rarity were used to identify important areas for conservation. A simulated annealing analysis was performed to evaluate and formulate effective new reserves for red oaks that are useful for conserving the ecosystems associated with them after the systematic conservation planning approach. Two main centers of species richness were detected. The northern Sierra Madre Oriental and Serranías Meridionales of Jalisco had the highest values of endemism. Fourteen areas were considered as priorities for conservation of red oak species based on the 26 priority political entities, 11 floristic units and the priority grid-cells obtained in the complementarity analysis. In the present network of Natural Protected Areas in Mexico and Central America, only 41.3% (31 species) of the red oak species are protected. The simulated annealing analysis indicated that to protect all 75 species of red oaks, 12 current natural protected areas need to be expanded by 120000 ha of additional land, and 26 new natural protected areas with 512500 ha need to be created. Red oaks are a useful model to identify areas for conservation based on species richness and endemism as a result of their wide geographic distribution and a high number of species. We evaluated and reformulated new reserves for red oaks that are also useful for the conservation of ecosystems associated with them.

Genetic structure of Plasmodium falciparum populations across the Honduras-Nicaragua border.

Science.gov (United States)

Larrañaga, Nerea; Mejía, Rosa E; Hormaza, José I; Montoya, Alberto; Soto, Aida; Fontecha, Gustavo A

2013-10-04

The Caribbean coast of Central America remains an area of malaria transmission caused by Plasmodium falciparum despite the fact that morbidity has been reduced in recent years. Parasite populations in that region show interesting characteristics such as chloroquine susceptibility and low mortality rates. Genetic structure and diversity of P. falciparum populations in the Honduras-Nicaragua border were analysed in this study. Seven neutral microsatellite loci were analysed in 110 P. falciparum isolates from endemic areas of Honduras (n = 77) and Nicaragua (n = 33), mostly from the border region called the Moskitia. Several analyses concerning the genetic diversity, linkage disequilibrium, population structure, molecular variance, and haplotype clustering were conducted. There was a low level of genetic diversity in P. falciparum populations from Honduras and Nicaragua. Expected heterozigosity (H(e)) results were similarly low for both populations. A moderate differentiation was revealed by the F(ST) index between both populations, and two putative clusters were defined through a structure analysis. The main cluster grouped most of samples from Honduras and Nicaragua, while the second cluster was smaller and included all the samples from the Siuna community in Nicaragua. This result could partially explain the stronger linkage disequilibrium (LD) in the parasite population from that country. These findings are congruent with the decreasing rates of malaria endemicity in Central America.

Jaguar taxonomy and genetic diversity for southern Arizona, United States, and Sonora, Mexico

Science.gov (United States)

Culver, Melanie; Hein, Alexander Ochoa

2016-06-28

Executive SummaryThe jaguar is the largest Neotropical felid and the only extant representative of the genus Panthera in the Americas. In recorded history, the jaguars range has extended from the Southern United States, throughout Mexico, to Central and South America, and they occupy a wide variety of habitats. A previous jaguar genetic study found high historical levels of gene flow among jaguar populations over broad areas but did not include any samples of jaguar from the States of Arizona, United States, or Sonora, Mexico. Arizona and Sonora have been part of the historical distribution of jaguars; however, poaching and habitat fragmentation have limited their distribution until they were declared extinct in the United States and endangered in Sonora. Therefore, a need was apparent to have this northernmost (Arizona/Sonora) jaguar population included in an overall jaguar molecular taxonomy and genetic diversity analyses. In this study, we used molecular genetic markers to examine diversity and taxonomy for jaguars in the Northwestern Jaguar Recovery Unit (NJRU; Sonora, Sinaloa, and Jalisco, Mexico; and southern Arizona and New Mexico, United States) relative to jaguars in other parts of the jaguar range (Central and South America). The objectives of this study were to:Collect opportunistic jaguar samples (hide, blood, hair, saliva, and scat), from historical and current individuals, that originated in NJRU areas of Arizona, New Mexico, and Sonora;Use these samples to assess molecular taxonomy of NJRU jaguars compared to data from a previous study of jaguars rangewide; andDevelop suggestions for conservation of NJRU jaguars based on the results.

Accommodation of missing shear strain in the Central Walker Lane, western North America: Constraints from dense GPS measurements

Science.gov (United States)

Bormann, Jayne M.; Hammond, William C.; Kreemer, Corné; Blewitt, Geoffrey

2016-04-01

We present 264 new interseismic GPS velocities from the Mobile Array of GPS for Nevada Transtension (MAGNET) and continuous GPS networks that measure Pacific-North American plate boundary deformation in the Central Walker Lane. Relative to a North America-fixed reference frame, northwestward velocities increase smoothly from ∼4 mm/yr in the Basin and Range province to 12.2 mm/yr in the central Sierra Nevada resulting in a Central Walker Lane deformation budget of ∼8 mm/yr. We use an elastic block model to estimate fault slip and block rotation rates and patterns of deformation from the GPS velocities. Right-lateral shear is distributed throughout the Central Walker Lane with strike-slip rates generally Bodie Hills, Carson Domain, and Mina Deflection are between 1-4°/Myr, lower than published paleomagnetic rotation rates, suggesting that block rotation rates have decreased since the Late to Middle Miocene.

In the heartland of Eurasia: the multilocus genetic landscape of Central Asian populations

Science.gov (United States)

Martínez-Cruz, Begoña; Vitalis, Renaud; Ségurel, Laure; Austerlitz, Frédéric; Georges, Myriam; Théry, Sylvain; Quintana-Murci, Lluis; Hegay, Tatyana; Aldashev, Almaz; Nasyrova, Firuza; Heyer, Evelyne

2011-01-01

Located in the Eurasian heartland, Central Asia has played a major role in both the early spread of modern humans out of Africa and the more recent settlements of differentiated populations across Eurasia. A detailed knowledge of the peopling in this vast region would therefore greatly improve our understanding of range expansions, colonizations and recurrent migrations, including the impact of the historical expansion of eastern nomadic groups that occurred in Central Asia. However, despite its presumable importance, little is known about the level and the distribution of genetic variation in this region. We genotyped 26 Indo-Iranian- and Turkic-speaking populations, belonging to six different ethnic groups, at 27 autosomal microsatellite loci. The analysis of genetic variation reveals that Central Asian diversity is mainly shaped by linguistic affiliation, with Turkic-speaking populations forming a cluster more closely related to East-Asian populations and Indo-Iranian speakers forming a cluster closer to Western Eurasians. The scattered position of Uzbeks across Turkic- and Indo-Iranian-speaking populations may reflect their origins from the union of different tribes. We propose that the complex genetic landscape of Central Asian populations results from the movements of eastern, Turkic-speaking groups during historical times, into a long-lasting group of settled populations, which may be represented nowadays by Tajiks and Turkmen. Contrary to what is generally thought, our results suggest that the recurrent expansions of eastern nomadic groups did not result in the complete replacement of local populations, but rather into partial admixture. PMID:20823912

NATURAL AND ANTHROPIC RISK STUDIES IN FOUR DECADES IN THE GEOGRAPHICAL JOURNAL OF CENTRAL AMERICA (1974 - 2015)

OpenAIRE

Quesada-Román, Adolfo

2017-01-01

The aim of this work is to identify the influence of the international and national epistemological trends and the techniques in the risk management of disasters (RMD) in Costa Rica. To do this, the journal papers of the Geographical Journal of Central America between 1974 and 2015 were analyzed -114 included topics related to natural and anthropogenic risks. They were classified into eight thematic classes: seismic hazards, volcanic hazards, slope processes hazards, hydrometeorological hazar...

The Tonalá fault in southeastern Mexico: Evidence that the Central America forearc sliver is not being detached?

Science.gov (United States)

Guzman-Speziale, M.; Molina-Garza, R. S.

2012-12-01

The Tonalá fault is a NW-SE oriented feature that flanks the Chiapas Massif on its southwestern side. Several authors coincide that the fault originally developed as a right-lateral structure in the Jurassic, but was reactivated as a left-lateral fault in the Miocene. Seismicity along the fault is low: Only one earthquake with magnitude 5.0 or larger is reported along the Tonalá fault in the years 1964 to present. Fault-plane solutions determined by the Mexican Seismological Survey for earthquakes along the fault show left-lateral, strike-slip faulting. The Tonalá fault lies on the northwestern continuation of the Central America volcanic arc. The volcanic arc is the site of medium-sized (magnitudes up to 6.5) shallow, right-lateral, strike-slip earthquakes. This has led several workers to propose that the forearc sliver is being detached from the Caribbean plate along the arc, moving northward. GPS studies have confirmed relative motion between the Chortis block and the forearc sliver. Recent and current motion along the Tonalá fault is in contradiction with motion and detachment of the forearc sliver along the Central America volcanic arc. Left-lateral motion along it cannot accomodate northwest displacement of the forearc sliver. Motion of the Central America forearc would require NW directed compression between the continental shelf of Chiapas and the forearc itself, which is not observed. Therefore, either another fault (or faults) accomodates right-lateral motion and detachment of the forearc sliver, or the sliver is not being detached and relative motion between the forearc sliver and the Chortis block corresponds to displacement of the latter. We suggest that, as proposed by previous authors, the Tonalá fault is instead part of a fault system that runs from the state of Oaxaca (the Valle Nacional fault), forming an arc concave to the northeast, and running perpendicular to the maximum slope of subduction in the area.

Genetic Diversity and Population Genetics of Mosquitoes (Diptera: Culicidae: Culex spp. from the Sonoran Desert of North America

Directory of Open Access Journals (Sweden)

Edward Pfeiler

2013-01-01

Full Text Available The population genetics and phylogenetic relationships of Culex mosquitoes inhabiting the Sonoran Desert region of North America were studied using mitochondrial DNA and microsatellite molecular markers. Phylogenetic analyses of mitochondrial cytochrome c oxidase subunit I (COI from mosquitoes collected over a wide geographic area, including the Baja California peninsula, and mainland localities in southern Arizona, USA and Sonora, Mexico, showed several well-supported partitions corresponding to Cx. quinquefasciatus, Cx. tarsalis, and two unidentified species, Culex sp. 1 and sp. 2. Culex quinquefasciatus was found at all localities and was the most abundant species collected. Culex tarsalis was collected only at Tucson, Arizona and Guaymas, Sonora. The two unidentified species of Culex were most abundant at Navojoa in southern Sonora. Haplotype and nucleotide diversities in the COI gene segment were substantially lower in Cx. quinquefasciatus compared with the other three species. Analysis of molecular variance revealed little structure among seven populations of Cx. quinquefasciatus, whereas significant structure was found between the two populations of Cx. tarsalis. Evidence for an historical population expansion beginning in the Pleistocene was found for Cx. tarsalis. Possible explanations for the large differences in genetic diversity between Cx. quinquefasciatus and the other species of Culex are presented.

Genetic Diversity and Population Genetics of Mosquitoes (Diptera: Culicidae: Culex spp.) from the Sonoran Desert of North America

Science.gov (United States)

Pfeiler, Edward; Flores-López, Carlos A.; Mada-Vélez, Jesús Gerardo; Escalante-Verdugo, Juan; Markow, Therese A.

2013-01-01

The population genetics and phylogenetic relationships of Culex mosquitoes inhabiting the Sonoran Desert region of North America were studied using mitochondrial DNA and microsatellite molecular markers. Phylogenetic analyses of mitochondrial cytochrome c oxidase subunit I (COI) from mosquitoes collected over a wide geographic area, including the Baja California peninsula, and mainland localities in southern Arizona, USA and Sonora, Mexico, showed several well-supported partitions corresponding to Cx. quinquefasciatus, Cx. tarsalis, and two unidentified species, Culex sp. 1 and sp. 2. Culex quinquefasciatus was found at all localities and was the most abundant species collected. Culex tarsalis was collected only at Tucson, Arizona and Guaymas, Sonora. The two unidentified species of Culex were most abundant at Navojoa in southern Sonora. Haplotype and nucleotide diversities in the COI gene segment were substantially lower in Cx. quinquefasciatus compared with the other three species. Analysis of molecular variance revealed little structure among seven populations of Cx. quinquefasciatus, whereas significant structure was found between the two populations of Cx. tarsalis. Evidence for an historical population expansion beginning in the Pleistocene was found for Cx. tarsalis. Possible explanations for the large differences in genetic diversity between Cx. quinquefasciatus and the other species of Culex are presented. PMID:24302868

Pleistocene to holocene expansion of the black-belt cichlid in Central America, Vieja maculicauda (Teleostei: Cichlidae.

Directory of Open Access Journals (Sweden)

Caleb D McMahan

Full Text Available The distributions of many Northern Hemisphere organisms have been influenced by fluctuations in sea level and climatic conditions during Pleistocene interglacial periods. These cycles are associated with range contraction and refugia for northern-distributed organisms as a response to glaciers. However, lower sea levels in the tropics and sub-tropics created available habitat for expansion of the ranges of freshwater organisms. The goal of this study was to use ecological niche modeling to test the hypothesis of north to south range expansion of Vieja maculicauda associated with Pleistocene glacial cycles. Understanding the biogeography of this widespread species may help us better understand the geology and interconnectivity of Central American freshwaters. Occurrence data for V. maculicauda was based on georeferencing of all museum records of specimens recovered from FishNet2. General patterns of phylogeographic structure were assessed with mtDNA. Present day niche models were generated and subsequently projected onto paleoclimatic maps of the region during the Last Interglacial, Last Glacial Maximum, and mid-Holocene. Phylogenetic analysis of mtDNA sequence data showed no phylogeographic structure throughout the range of this widespread species. Present day niche models were congruent with the observed distribution of V. maculicauda in Central America. Results showed a lack of suitable freshwater habitat in northern Central America and Mexico during the Last Interglacial, with greatest range expansion during the Last Glacial Maximum and mid-Holocene. Results support the hypothesis of a north to south range expansion of V. maculicauda associated with glacial cycles. The wide distribution of this species compared to other closely related cichlids indicates the latter did not respond to the degree of V. maculicauda in expansion of their distributions. Future work aimed at comparisons with other species and modeling of future climatic scenarios

Detailed genetic structure of European bitterling populations in Central Europe

Directory of Open Access Journals (Sweden)

Veronika Bartáková

2015-11-01

Full Text Available The European bitterling (Rhodeus amarus is a small cyprinid fish whose populations declined markedly between 1950 and 1980. However, its range currently expands, partly due to human-assisted introductions. We determined the genetic variability and detailed spatial structure among bitterling populations in Central Europe and tested alternative hypotheses about colonization of this area. Twelve polymorphic microsatellite loci on a large sample of 688 individuals had been used to analyse genetic variability and population structure. Samples originated from 27 localities with emphasis on area of the Czech Republic where three major sea drainages (Black, Baltic, and Northern Sea meet. Highly variable level of intrapopulation genetic variability had generally been detected and a recent decrease in numbers (“bottleneck” had been indicated by genetic data among six populations. High level of interpopulation differentiation was identified even within the basins. There was a significant role of genetic drift and indications of low dispersal ability of R. amarus. Surprisingly, the Odra River was inhabited by two distinct populations without any genetic signatures of a secondary contact. Czech part of the Odra (Baltic basin was colonized from the Danubian refugium (similarly to adjacent Danubian basin rivers including the Morava, while Polish part of the Odra was genetically similar to the populations in the Vistula River (Baltic basin, that has been colonized by a different (Eastern phylogeographic lineage of R. amarus. Most Czech R. amarus populations were colonized from the Danubian refugium, suggesting potential for a human-mediated colonization of the Odra or Elbe Rivers by R. amarus. One Elbe basin population was genetically mixed from the two (Danubian and Eastern phylogeographic lineages. In general the Czech populations of R. amarus were genetically stable except for a single population which has probably been recently introduced. This research

Plants used in the traditional medicine of Mesoamerica (Mexico and Central America) and the Caribbean for the treatment of obesity.

Science.gov (United States)

Alonso-Castro, Angel Josabad; Domínguez, Fabiola; Zapata-Morales, Juan Ramón; Carranza-Álvarez, Candy

2015-12-04

Obesity is a worldwide medical concern. New ethnobotanical information regarding the antiobesity effect of medicinal plants has been obtained in the last 30 years in response to socio-demographic changes and high-fat diets became common. This review provides a summary of medicinal plants used in Mexico, Central America and the Caribbean for the empirical treatment of obesity in terms of ethnobotany, toxicity, pharmacology, conservation status, trade and chemistry. Bibliographic investigation was performed by analyzing recognized books, undergraduate and postgraduate theses and peer-reviewed scientific articles, consulting worldwide accepted scientific databases from the last four decades. Medicinal plants used for the treatment of obesity were classified in two categories: (1) plants with pharmacological evidence and (2) plants without pharmacological evidence. A total of 139 plant species, belonging to 61 families, native to Mexico, Central America and the Caribbean that are used for the empirical treatment of obesity were recorded. From these plants, 33 were investigated in scientific studies, and 106 plants lacked scientific investigation. Medicinal plants were experimentally studied in vitro (21 plants) and in vivo (16 plants). A total of 4 compounds isolated from medicinal plants used for the empirical treatment of obesity have been tested in vitro (2 compounds) and in vivo (4 compounds) studies. No clinical trials on obese subjects (BMI>30 kg/m(2)) have been performed using the medicinal plants cited in this review. There are no herbal-based products approved in Mexico for the treatment of obesity. There are a limited number of scientific studies published on medicinal plants from Mexico, Central America and the Caribbean used for the treatment of obesity. This review highlights the need to perform pharmacological, phytochemical, toxicological and ethnobotanical studies with medicinal flora to obtain new antiobesity agents. Copyright © 2015 Elsevier Ireland

Genome-Wide Analysis Provides Evidence on the Genetic Relatedness of the Emergent Xylella fastidiosa Genotype in Italy to Isolates from Central America.

Science.gov (United States)

Giampetruzzi, Annalisa; Saponari, Maria; Loconsole, Giuliana; Boscia, Donato; Savino, Vito Nicola; Almeida, Rodrigo P P; Zicca, Stefania; Landa, Blanca B; Chacón-Diaz, Carlos; Saldarelli, Pasquale

2017-07-01

Xylella fastidiosa is a plant-pathogenic bacterium recently introduced in Europe that is causing decline in olive trees in the South of Italy. Genetic studies have consistently shown that the bacterial genotype recovered from infected olive trees belongs to the sequence type ST53 within subspecies pauca. This genotype, ST53, has also been reported to occur in Costa Rica. The ancestry of ST53 was recently clarified, showing it contains alleles that are monophyletic with those of subsp. pauca in South America. To more robustly determine the phylogenetic placement of ST53 within X. fastidiosa, we performed a comparative analysis based on single nucleotide polymorphisms (SNPs) and the study of the pan-genome of the 27 currently public available whole genome sequences of X. fastidiosa. The resulting maximum-parsimony and maximum likelihood trees constructed using the SNPs and the pan-genome analysis are consistent with previously described X. fastidiosa taxonomy, distinguishing the subsp. fastidiosa, multiplex, pauca, sandyi, and morus. Within the subsp. pauca, the Italian and three Costa Rican isolates, all belonging to ST53, formed a compact phylotype in a clade divergent from the South American pauca isolates, also distinct from the recently described coffee isolate CFBP8072 imported into Europe from Ecuador. These findings were also supported by the gene characterization of a conjugative plasmid shared by all the four ST53 isolates. Furthermore, isolates of the ST53 clade possess an exclusive locus encoding a putative ATP-binding protein belonging to the family of histidine kinase-like ATPase gene, which is not present in isolates from the subspecies multiplex, sandyi, and pauca, but was detected in ST21 isolates of the subspecies fastidiosa from Costa Rica. The clustering and distinctiveness of the ST53 isolates supports the hypothesis of their common origin, and the limited genetic diversity among these isolates suggests this is an emerging clade within subsp

Enclaves of genetic diversity resisted Inca impacts on population history.

Science.gov (United States)

Barbieri, Chiara; Sandoval, José R; Valqui, Jairo; Shimelman, Aviva; Ziemendorff, Stefan; Schröder, Roland; Geppert, Maria; Roewer, Lutz; Gray, Russell; Stoneking, Mark; Fujita, Ricardo; Heggarty, Paul

2017-12-12

The Inca Empire is claimed to have driven massive population movements in western South America, and to have spread Quechua, the most widely-spoken language family of the indigenous Americas. A test-case is the Chachapoyas region of northern Peru, reported as a focal point of Inca population displacements. Chachapoyas also spans the environmental, cultural and demographic divides between Amazonia and the Andes, and stands along the lowest-altitude corridor from the rainforest to the Pacific coast. Following a sampling strategy informed by linguistic data, we collected 119 samples, analysed for full mtDNA genomes and Y-chromosome STRs. We report a high indigenous component, which stands apart from the network of intense genetic exchange in the core central zone of Andean civilization, and is also distinct from neighbouring populations. This unique genetic profile challenges the routine assumption of large-scale population relocations by the Incas. Furthermore, speakers of Chachapoyas Quechua are found to share no particular genetic similarity or gene-flow with Quechua speakers elsewhere, suggesting that here the language spread primarily by cultural diffusion, not migration. Our results demonstrate how population genetics, when fully guided by the archaeological, historical and linguistic records, can inform multiple disciplines within anthropology.

Mercury in Forage Fish from Mexico and Central America: Implications for Fish-Eating Birds.

Science.gov (United States)

Elliott, John E; Kirk, David A; Elliott, Kyle H; Dorzinsky, Jessica; Lee, Sandi; Inzunza, Ernesto Ruelas; Cheng, Kimberly M T; Scheuhammer, Tony; Shaw, Patrick

2015-11-01

Mercury (Hg) is a global contaminant of aquatic food chains. Aquatic birds, such as the osprey (Pandion haliaetus), with migratory populations breeding in Canada and the northern United States and wintering in the Central and South America, can be exposed to mercury on both the breeding and wintering ranges. We examined Hg levels in 14 fish taxa from 24 osprey wintering sites identified from satellite telemetry. Our main goal was to determine whether fish species that feature in the diet of overwintering and resident fish-eating birds reached toxicity thresholds for Hg. Mean Hg levels in fish whole carcasses ranged from a high of 0.18 µg g(-1) (wet weight) in Scomberomorus sierra to a low of 0.009 µg g(-1) in Catostomidae. Average Hg levels were within published toxicity threshold values in forage fish for only two sites in Mexico (Puerto Vallarta and San Blas Estuary), and all were marine species, such as mackerel (Scomberomorus sierra), sea catfish (Ariopus spp.), and sardinas species (Centropomus spp.). Except for one sample from Nicaragua, sea catfish from Puerto Morazan, none of the fish from sites in Central America had Hg levels which exceeded the thresholds. Nonmetric multidimensional scaling revealed geographical differences in Hg levels with significant pairwise differences between sites along the Pacific Ocean (Mexico) versus the Bay of Campeche, partly due to differences in species composition of sampled fish (and species distributions). Hg increased with trophic level, as assessed by nitrogen stable isotope ratios (δ(15)N but not δ(13)C), in freshwater and marine, but not estuarine, environments. Hg concentrations in forage fish do not account for the elevated Hg reported for many osprey populations on the breeding grounds, thus primary sources of contamination appear to be in the north.

An investigation of thermal anomalies in the Central American volcanic chain and evaluation of the utility of thermal anomaly monitoring in the prediction of volcanic eruptions. [Central America

Science.gov (United States)

Stoiber, R. E. (Principal Investigator); Rose, W. I., Jr.

1975-01-01

The author has identified the following significant results. Ground truth data collection proves that significant anomalies exist at 13 volcanoes within the test site of Central America. The dimensions and temperature contrast of these ten anomalies are large enough to be detected by the Skylab 192 instrument. The dimensions and intensity of thermal anomalies have changed at most of these volcanoes during the Skylab mission.

Comparison of population genetic patterns in two widespread freshwater mussels with contrasting life histories in western North America.

Science.gov (United States)

Mock, K E; Brim Box, J C; Chong, J P; Furnish, J; Howard, J K

2013-12-01

We investigate population genetic structuring in Margaritifera falcata, a freshwater mussel native to western North America, across the majority of its geographical range. We find shallow rangewide genetic structure, strong population-level structuring and very low population diversity in this species, using both mitochondrial sequence and nuclear microsatellite data. We contrast these patterns with previous findings in another freshwater mussel species group (Anodonta californiensis/A. nuttalliana) occupying the same continental region and many of the same watersheds. We conclude that differences are likely caused by contrasting life history attributes between genera, particularly host fish requirements and hermaphroditism. Further, we demonstrate the occurrence of a 'hotspot' for genetic diversity in both groups of mussels, occurring in the vicinity of the lower Columbia River drainage. We suggest that stream hierarchy may be responsible for this pattern and may produce similar patterns in other widespread freshwater species. © 2013 John Wiley & Sons Ltd.

"Balkan journal of medical genetics"--facts, editorial policies, practices and challenges.

Science.gov (United States)

Plaseska Karanfilska, Dijana; Sukarova Stefanovska, Emilija

2014-01-01

The Balkan Journal of Medical Genetics (BJMG) is an international, open access journal that publishes scientific papers covering different aspects of medical genetics. It is published by the Macedonian Academy of Sciences and Arts twice a year in both printed and electronic versions. BJMG is covered by many abstracting and indexing databases, including PubMed Central and Thomson Reuters. Although there are many journals in the field of medical genetics, only a few come from regions outside Western Europe and North America. Being one of these few journals, BJMG aims to promote genetics and research on this topic in the Balkan countries and beyond. BJMG's ultimate goal is to raise the scientific quality and metrics of the journal and provide a better place for BJMG in the community of scientific journals.

Fanconi anemia: correlating central nervous system malformations and genetic complementation groups.

Science.gov (United States)

Johnson-Tesch, Benjamin A; Gawande, Rakhee S; Zhang, Lei; MacMillan, Margaret L; Nascene, David R

2017-06-01

Congenital central nervous system abnormalities in children with Fanconi anemia are poorly characterized, especially with regard to specific genetic complementation groups. To characterize the impact of genetic complementation groups on central nervous system anatomy. Through chart review we identified 36 patients with Fanconi anemia with available brain MRIs at the University of Minnesota (average age, 11.3 years; range, 1-43 years; M:F=19:17), which we reviewed and compared to 19 age- and sex-matched controls (average age, 7.9 years; range, 2-18 years; M:F=9:10). Genotypic information was available for 27 patients (15 FA-A, 2 FA-C, 3 FA-G, and 7 FA-D1 [biallelic mutations in BRCA2 gene]). Of the 36 patients, 61% had at least one congenital central nervous system or skull base abnormality. These included hypoplastic clivus (n=12), hypoplastic adenohypophysis (n=11), platybasia (n=8), pontocerebellar hypoplasia (n=7), isolated pontine hypoplasia (n=4), isolated vermis hypoplasia (n=3), and ectopic neurohypophysis (n=6). Average pituitary volume was significantly less in patients with Fanconi anemia (PFanconi anemia patients (P=0.006), but the basal angle of those with FA-D1 was not significantly different from controls (P=0.239). Clivus length was less in the Fanconi anemia group (P=0.002), but significance was only observed in the FA-D1 subgroup (PFanconi anemia have higher incidences of ectopic neurohypophysis, adenohypophysis hypoplasia, platybasia and other midline central nervous system skull base posterior fossa abnormalities than age- and sex-matched controls. Patients with posterior fossa abnormalities, including pontocerebellar hypoplasia, are more likely to have biallelic BRCA2 mutations.

Scale-dependent effects of a heterogeneous landscape on genetic differentiation in the Central American squirrel monkey (Saimiri oerstedii.

Directory of Open Access Journals (Sweden)

Mary E Blair

Full Text Available Landscape genetic studies offer a fine-scale understanding of how habitat heterogeneity influences population genetic structure. We examined population genetic structure and conducted a landscape genetic analysis for the endangered Central American Squirrel Monkey (Saimiri oerstedii that lives in the fragmented, human-modified habitats of the Central Pacific region of Costa Rica. We analyzed non-invasively collected fecal samples from 244 individuals from 14 groups for 16 microsatellite markers. We found two geographically separate genetic clusters in the Central Pacific region with evidence of recent gene flow among them. We also found significant differentiation among groups of S. o. citrinellus using pairwise F(ST comparisons. These groups are in fragments of secondary forest separated by unsuitable "matrix" habitats such as cattle pasture, commercial African oil palm plantations, and human residential areas. We used an individual-based landscape genetic approach to measure spatial patterns of genetic variance while taking into account landscape heterogeneity. We found that large, commercial oil palm plantations represent moderate barriers to gene flow between populations, but cattle pastures, rivers, and residential areas do not. However, the influence of oil palm plantations on genetic variance was diminished when we restricted analyses to within population pairs, suggesting that their effect is scale-dependent and manifests during longer dispersal events among populations. We show that when landscape genetic methods are applied rigorously and at the right scale, they are sensitive enough to track population processes even in species with long, overlapping generations such as primates. Thus landscape genetic approaches are extremely valuable for the conservation management of a diverse array of endangered species in heterogeneous, human-modified habitats. Our results also stress the importance of explicitly considering the heterogeneity of

Chronic kidney disease of nontraditional etiology in Central America: a provisional epidemiologic case definition for surveillance and epidemiologic studies.

Science.gov (United States)

Lozier, Matthew; Turcios-Ruiz, Reina Maria; Noonan, Gary; Ordunez, Pedro

2016-11-01

SYNOPSIS Over the last two decades, experts have reported a rising number of deaths caused by chronic kidney disease (CKD) along the Pacific coast of Central America, from southern Mexico to Costa Rica. However, this specific disease is not associated with traditional causes of CKD, such as aging, diabetes, or hypertension. Rather, this disease is a chronic interstitial nephritis termed chronic kidney disease of nontraditional etiology (CKDnT). According to the Pan American Health Organization (PAHO) mortality database, there are elevated rates of deaths related to kidney disease in many of these countries, with the highest rates being reported in El Salvador and Nicaragua. This condition has been identified in certain agricultural communities, predominantly among male farmworkers. Since CKD surveillance systems in Central America are under development or nonexistent, experts and governmental bodies have recommended creating standardized case definitions for surveillance purposes to monitor and characterize this epidemiological situation. A group of experts from Central American ministries of health, the U.S. Centers for Disease Control and Prevention (CDC), and PAHO held a workshop in Guatemala to discuss CKDnT epidemiologic case definitions. In this paper, we propose that CKD in general be identified by the standard definition internationally accepted and that a suspect case of CKDnT be defined as a person age CKDnT is defined as a suspect case with the same findings confirmed three or more months later.

Patterns of admixture and population structure in native populations of Northwest North America.

Directory of Open Access Journals (Sweden)

Paul Verdu

2014-08-01

Full Text Available The initial contact of European populations with indigenous populations of the Americas produced diverse admixture processes across North, Central, and South America. Recent studies have examined the genetic structure of indigenous populations of Latin America and the Caribbean and their admixed descendants, reporting on the genomic impact of the history of admixture with colonizing populations of European and African ancestry. However, relatively little genomic research has been conducted on admixture in indigenous North American populations. In this study, we analyze genomic data at 475,109 single-nucleotide polymorphisms sampled in indigenous peoples of the Pacific Northwest in British Columbia and Southeast Alaska, populations with a well-documented history of contact with European and Asian traders, fishermen, and contract laborers. We find that the indigenous populations of the Pacific Northwest have higher gene diversity than Latin American indigenous populations. Among the Pacific Northwest populations, interior groups provide more evidence for East Asian admixture, whereas coastal groups have higher levels of European admixture. In contrast with many Latin American indigenous populations, the variance of admixture is high in each of the Pacific Northwest indigenous populations, as expected for recent and ongoing admixture processes. The results reveal some similarities but notable differences between admixture patterns in the Pacific Northwest and those in Latin America, contributing to a more detailed understanding of the genomic consequences of European colonization events throughout the Americas.

Methodological and Practical Considerations for DevelopingMultiproject Baselines for Electric Power and Cement Industry Projects inCentral America

Energy Technology Data Exchange (ETDEWEB)

Murtishaw, Scott; Sathaye, Jayant; Galitsky, Christina; Dorion,Kristel

2004-09-02

The Lawrence Berkeley National Laboratory (Berkeley Lab) andthe Center for Sustainable Development in the Americas (CSDA) conductedtechnical studies and organized two training workshops to developcapacity in Central America for the evaluation of climate changeprojects. This paper describes the results of two baseline case studiesconducted for these workshops, one for the power sector and one for thecement industry, that were devised to illustrate certain approaches tobaseline setting. Multiproject baseline emission rates (BERs) for themain Guatemalan electricity grid were calculated from 2001 data. Inrecent years, the Guatemalan power sector has experienced rapid growth;thus, a sufficient number of new plants have been built to estimateviable BERs. We found that BERs for baseload plants offsetting additionalbaseload capacity ranged from 0.702 kgCO2/kWh (using a weighted averagestringency) to 0.507 kgCO2/kWh (using a 10th percentile stringency),while the baseline for plants offsetting load-followingcapacity is lowerat 0.567 kgCO2/kWh. For power displaced from existing load-followingplants, the rate is higher, 0.735 kgCO2/kWh, as a result of the age ofsome plants used for meeting peak loads and the infrequency of their use.The approved consolidated methodology for the Clean Development Mechanismyields a single rate of 0.753 kgCO2/kWh. Due to the relatively smallnumber of cement plants in the region and the regional nature of thecement market, all of Central America was chosen as the geographicboundary for setting cement industry BERs. Unfortunately, actualoperations and output data were unobtainable for most of the plants inthe region, and many data were estimated. Cement industry BERs rangedfrom 205 kgCO2 to 225 kgCO2 per metric ton of cement.

Imaging paleoslabs in the D″ layer beneath Central America and the Caribbean using seismic waveform inversion.

Science.gov (United States)

Borgeaud, Anselme F E; Kawai, Kenji; Konishi, Kensuke; Geller, Robert J

2017-11-01

D″ (Dee double prime), the lowermost layer of the Earth's mantle, is the thermal boundary layer (TBL) of mantle convection immediately above the Earth's liquid outer core. As the origin of upwelling of hot material and the destination of paleoslabs (downwelling cold slab remnants), D″ plays a major role in the Earth's evolution. D″ beneath Central America and the Caribbean is of particular geodynamical interest, because the paleo- and present Pacific plates have been subducting beneath the western margin of Pangaea since ~250 million years ago, which implies that paleoslabs could have reached the lowermost mantle. We conduct waveform inversion using a data set of ~7700 transverse component records to infer the detailed three-dimensional S-velocity structure in the lowermost 400 km of the mantle in the study region so that we can investigate how cold paleoslabs interact with the hot TBL above the core-mantle boundary (CMB). We can obtain high-resolution images because the lowermost mantle here is densely sampled by seismic waves due to the full deployment of the USArray broadband seismic stations during 2004-2015. We find two distinct strong high-velocity anomalies, which we interpret as paleoslabs, just above the CMB beneath Central America and Venezuela, respectively, surrounded by low-velocity regions. Strong low-velocity anomalies concentrated in the lowermost 100 km of the mantle suggest the existence of chemically distinct denser material connected to low-velocity anomalies in the lower mantle inferred by previous studies, suggesting that plate tectonics on the Earth's surface might control the modality of convection in the lower mantle.

Biofuels in Central America, a real potential for commercial production

Energy Technology Data Exchange (ETDEWEB)

Garcia, O.L. (Regional Coordinator Energy and Environmental Partnership with Central America EEP (El Salvador))

2007-07-01

The purpose of this paper is to show the current capabilities of the Central American countries regarding the production of biofuels, and the real potential in increasing the volumes produced and the impacts that can be generated if a non sustainable policy is followed for achieving the targets of biofuel production. Due to the world oil price crisis, and the fact that Central American counties are fully dependant on oil imports (just Guatemala and Belize produce little amounts of oil), just to mention, in some countries the imports of oil is equivalent to the 40% of the total exports, the region started to look for massive production of biofuels, something that it is not new for us. The countries have started with programs for producing ethanol from sugar cane, because it is one of the most strongest industries in Central America and they have all the infrastructure and financial sources to develop this project. The ethanol is a biofuel that can be mixed with gasoline or a complete substitute. Another biofuel that is currently under develop, is the production of biodiesel, and the main source for it nowadays is the Palm oil, where Costa Rica, Honduras and Guatemala have already commercial productions of crude palm oil, but the principal use of it is for the food industry, but now it is under assessment for using part of it for biodiesel. EEP is now developing pilot programs for production of biodiesel from a native plant named Jatropha curcas, and up to now we have a commercial plantation in Guatemala, and we started as well in Honduras for start spreading this plantations. In El Salvador we installed a pilot processing plant for biodiesel that can be operated with multiple feed stock, such as Jatropha, palm oil, castor oil, vegetable used oil and others. Currently we have interesting and good results regarding the production of Jatropha, we have developed a methodology for its cropping, harvesting and processing. All the vehicles and equipment involved in the

Mapping occurrence of Taenia solium taeniosis/cysticercosis and areas at risk of porcine cysticercosis in Central America and the Caribbean basin.

Science.gov (United States)

Braae, Uffe Christian; Devleesschauwer, Brecht; Sithole, Fortune; Wang, Ziqi; Willingham, Arve Lee

2017-09-18

This study aimed to map the occurrence of Taenia solium taeniosis/cysticercosis at national level within Central America and the Caribbean basin, and to map the distribution of porcine cysticercosis at first-level administrative subdivision level (department level) and the porcine population at risk. This zoonotic parasite is believed to be widely endemic across most of Latin America. However, there is little information readily available for Central America and the Caribbean basin. Taenia solium has been ranked the most important foodborne parasitic hazard globally and within endemic areas is a common cause of preventable epilepsy. We conducted a structured literature search in PubMed, supplemented and crossed-referenced with relevant academic databases, grey literature, and active searches in identified literature, to identify all records of T. solium presence in Central America and the Caribbean basin between 1986 and April 2017. To retrieve grey literature, government entities, researchers and relevant institutions across the region were contacted in an attempt to cover all countries and territories. Identified records containing data on porcine cysticercosis were geo-referenced to identify department level distribution and compared to modelled distributions of pigs reared under extensive production systems. We identified 51 records of T. solium at the national level, covering 13 countries and an additional three countries were included based on World Organisation for Animal Health (OIE) reports, giving a total of 16 countries out of 41 with evidence of the parasite's presence. Screening records for porcine cysticercosis data at the departmental level confirmed porcine cysticercosis presence in 11 departments across six countries (Colombia, Guatemala, Honduras, Mexico, Nicaragua and Venezuela). When comparing these results to areas where pigs were kept in extensive production systems and areas where no information on porcine cysticercosis exists, it is apparent

Geoid modeling in Mexico and the collaboration with Central America and the Caribbean.

Science.gov (United States)

Avalos, D.; Gomez, R.

2012-12-01

The model of geoidal heights for Mexico, named GGM10, is presented as a geodetic tool to support vertical positioning in the context of regional height system unification. It is a purely gravimetric solution computed by the Stokes-Helmert technique in resolution of 2.5 arc minutes. This product from the Instituto Nacional de Estadistica y Geografia (INEGI) is released together with a series of 10 gravimetric models which add to the improvements in description of the gravity field. In the recent years, the INEGI joined the initiative of the U.S. National Geodetic Survey and the Canada's Geodetic Survey Division to promote the regional height system unification. In an effort to further improve the compatibility among national geoid models in the region, the INEGI has begun to champion a network of specialists that includes national representatives from Central America and the Caribbean. Through the opening of opportunities for training and more direct access to international agreements and discussions, the tropical region is gaining participation. Now a significantly increased number of countries is pushing for a future North and Central American geoid-based vertical datum as support of height system unification.eoidal height in Mexico, mapped from the model GGM10.

Fanconi anemia: correlating central nervous system malformations and genetic complementation groups

International Nuclear Information System (INIS)

Johnson-Tesch, Benjamin A.; Gawande, Rakhee S.; Nascene, David R.; Zhang, Lei; MacMillan, Margaret L.

2017-01-01

Congenital central nervous system abnormalities in children with Fanconi anemia are poorly characterized, especially with regard to specific genetic complementation groups. To characterize the impact of genetic complementation groups on central nervous system anatomy. Through chart review we identified 36 patients with Fanconi anemia with available brain MRIs at the University of Minnesota (average age, 11.3 years; range, 1-43 years; M:F=19:17), which we reviewed and compared to 19 age- and sex-matched controls (average age, 7.9 years; range, 2-18 years; M:F=9:10). Genotypic information was available for 27 patients (15 FA-A, 2 FA-C, 3 FA-G, and 7 FA-D1 [biallelic mutations in BRCA2 gene]). Of the 36 patients, 61% had at least one congenital central nervous system or skull base abnormality. These included hypoplastic clivus (n=12), hypoplastic adenohypophysis (n=11), platybasia (n=8), pontocerebellar hypoplasia (n=7), isolated pontine hypoplasia (n=4), isolated vermis hypoplasia (n=3), and ectopic neurohypophysis (n=6). Average pituitary volume was significantly less in patients with Fanconi anemia (P<0.0001) than in controls. Basal angle was significantly greater in Fanconi anemia patients (P=0.006), but the basal angle of those with FA-D1 was not significantly different from controls (P=0.239). Clivus length was less in the Fanconi anemia group (P=0.002), but significance was only observed in the FA-D1 subgroup (P<0.0001). Of the seven patients meeting criteria for pontocerebellar hypoplasia, six belonged to the FA-D1 group. Patients with Fanconi anemia have higher incidences of ectopic neurohypophysis, adenohypophysis hypoplasia, platybasia and other midline central nervous system skull base posterior fossa abnormalities than age- and sex-matched controls. Patients with posterior fossa abnormalities, including pontocerebellar hypoplasia, are more likely to have biallelic BRCA2 mutations. (orig.)

Fanconi anemia: correlating central nervous system malformations and genetic complementation groups

Energy Technology Data Exchange (ETDEWEB)

Johnson-Tesch, Benjamin A. [University of Minnesota, Department of Radiology, Minneapolis, MN (United States); Gawande, Rakhee S.; Nascene, David R. [University of Minnesota, Department of Radiology, Neuroradiology Section, Minneapolis, MN (United States); Zhang, Lei [University of Minnesota, Biostatistical Design and Analysis Centre, Minneapolis, MN (United States); MacMillan, Margaret L. [University of Minnesota, Blood and Marrow Transplant Program, Department of Pediatrics, Minneapolis, MN (United States)

2017-06-15

Congenital central nervous system abnormalities in children with Fanconi anemia are poorly characterized, especially with regard to specific genetic complementation groups. To characterize the impact of genetic complementation groups on central nervous system anatomy. Through chart review we identified 36 patients with Fanconi anemia with available brain MRIs at the University of Minnesota (average age, 11.3 years; range, 1-43 years; M:F=19:17), which we reviewed and compared to 19 age- and sex-matched controls (average age, 7.9 years; range, 2-18 years; M:F=9:10). Genotypic information was available for 27 patients (15 FA-A, 2 FA-C, 3 FA-G, and 7 FA-D1 [biallelic mutations in BRCA2 gene]). Of the 36 patients, 61% had at least one congenital central nervous system or skull base abnormality. These included hypoplastic clivus (n=12), hypoplastic adenohypophysis (n=11), platybasia (n=8), pontocerebellar hypoplasia (n=7), isolated pontine hypoplasia (n=4), isolated vermis hypoplasia (n=3), and ectopic neurohypophysis (n=6). Average pituitary volume was significantly less in patients with Fanconi anemia (P<0.0001) than in controls. Basal angle was significantly greater in Fanconi anemia patients (P=0.006), but the basal angle of those with FA-D1 was not significantly different from controls (P=0.239). Clivus length was less in the Fanconi anemia group (P=0.002), but significance was only observed in the FA-D1 subgroup (P<0.0001). Of the seven patients meeting criteria for pontocerebellar hypoplasia, six belonged to the FA-D1 group. Patients with Fanconi anemia have higher incidences of ectopic neurohypophysis, adenohypophysis hypoplasia, platybasia and other midline central nervous system skull base posterior fossa abnormalities than age- and sex-matched controls. Patients with posterior fossa abnormalities, including pontocerebellar hypoplasia, are more likely to have biallelic BRCA2 mutations. (orig.)

The use of genetics for the management of a recovering population: temporal assessment of migratory peregrine falcons in North America.

Directory of Open Access Journals (Sweden)

Jeff A Johnson

2010-11-01

Full Text Available Our ability to monitor populations or species that were once threatened or endangered and in the process of recovery is enhanced by using genetic methods to assess overall population stability and size over time. This can be accomplished most directly by obtaining genetic measures from temporally-spaced samples that reflect the overall stability of the population as given by changes in genetic diversity levels (allelic richness and heterozygosity, degree of population differentiation (F(ST and D(EST, and effective population size (N(e. The primary goal of any recovery effort is to produce a long-term self-sustaining population, and these genetic measures provide a metric by which we can gauge our progress and help make important management decisions.The peregrine falcon in North America (Falco peregrinus tundrius and anatum was delisted in 1994 and 1999, respectively, and its abundance will be monitored by the species Recovery Team every three years until 2015. Although the United States Fish and Wildlife Service makes a distinction between tundrius and anatum subspecies, our genetic results based on eleven microsatellite loci suggest limited differentiation that can be attributed to an isolation by distance relationship and warrant no delineation of these two subspecies in its northern latitudinal distribution from Alaska through Canada into Greenland. Using temporal samples collected at Padre Island, Texas during migration (seven temporal time periods between 1985-2007, no significant differences in genetic diversity or significant population differentiation in allele frequencies between time periods were observed and were indistinguishable from those obtained from tundrius/anatum breeding locations throughout their northern distribution. Estimates of harmonic mean N(e were variable and imprecise, but always greater than 500 when employing multiple temporal genetic methods.These results, including those from simulations to assess the power of

Drug Trafficking as a Lethal Regional Threat in Central America

Science.gov (United States)

2011-12-16

and Bolivia. 28 Panama It produces marijuana and serves as a critical transit country for all drugs coming from South America to the United...Colombian drug cartels. Paraguay This is a marijuana producing country. Its production probably never leaves South America; it is believed to supply...broad diversification of their products. The Mexican DTOs went through great efforts to establish laboratories for the cheap synthetic drugs in Mexico

Medicinal Plants from North and Central America and the Caribbean Considered Toxic for Humans: The Other Side of the Coin

Science.gov (United States)

Ruiz-Padilla, Alan Joel; Campos-Xolalpa, Nimsi; Carranza-Alvarez, Candy; Maldonado-Miranda, Juan Jose

2017-01-01

The consumption of medicinal plants has notably increased over the past two decades. People consider herbal products as safe because of their natural origin, without taking into consideration whether these plants contain a toxic principle. This represents a serious health problem. A bibliographic search was carried out using published scientific material on native plants from Mexico, Central America, and the Caribbean, which describe the ethnobotanical and toxicological information of medicinal plants empirically considered to be toxic. A total of 216 medicinal plants belonging to 77 families have been reported as toxic. Of these plants, 76 had been studied, and 140 plants lacked studies regarding their toxicological effects. The toxicity of 16 plants species has been reported in clinical cases, particularly in children. From these plants, deaths have been reported with the consumption of Chenopodium ambrosioides, Argemone mexicana, and Thevetia peruviana. In most of the cases, the principle of the plant responsible for the toxicity is unknown. There is limited information about the toxicity of medicinal plants used in Mexico, Central America, and the Caribbean. More toxicological studies are necessary to contribute information about the safe use of the medicinal plants cited in this review. PMID:29234446

Medicinal Plants from North and Central America and the Caribbean Considered Toxic for Humans: The Other Side of the Coin.

Science.gov (United States)

Alonso-Castro, Angel Josabad; Domínguez, Fabiola; Ruiz-Padilla, Alan Joel; Campos-Xolalpa, Nimsi; Zapata-Morales, Juan Ramón; Carranza-Alvarez, Candy; Maldonado-Miranda, Juan Jose

2017-01-01

The consumption of medicinal plants has notably increased over the past two decades. People consider herbal products as safe because of their natural origin, without taking into consideration whether these plants contain a toxic principle. This represents a serious health problem. A bibliographic search was carried out using published scientific material on native plants from Mexico, Central America, and the Caribbean, which describe the ethnobotanical and toxicological information of medicinal plants empirically considered to be toxic. A total of 216 medicinal plants belonging to 77 families have been reported as toxic. Of these plants, 76 had been studied, and 140 plants lacked studies regarding their toxicological effects. The toxicity of 16 plants species has been reported in clinical cases, particularly in children. From these plants, deaths have been reported with the consumption of Chenopodium ambrosioides , Argemone mexicana , and Thevetia peruviana . In most of the cases, the principle of the plant responsible for the toxicity is unknown. There is limited information about the toxicity of medicinal plants used in Mexico, Central America, and the Caribbean. More toxicological studies are necessary to contribute information about the safe use of the medicinal plants cited in this review.

Medicinal Plants from North and Central America and the Caribbean Considered Toxic for Humans: The Other Side of the Coin

Directory of Open Access Journals (Sweden)

Angel Josabad Alonso-Castro

2017-01-01

Full Text Available The consumption of medicinal plants has notably increased over the past two decades. People consider herbal products as safe because of their natural origin, without taking into consideration whether these plants contain a toxic principle. This represents a serious health problem. A bibliographic search was carried out using published scientific material on native plants from Mexico, Central America, and the Caribbean, which describe the ethnobotanical and toxicological information of medicinal plants empirically considered to be toxic. A total of 216 medicinal plants belonging to 77 families have been reported as toxic. Of these plants, 76 had been studied, and 140 plants lacked studies regarding their toxicological effects. The toxicity of 16 plants species has been reported in clinical cases, particularly in children. From these plants, deaths have been reported with the consumption of Chenopodium ambrosioides, Argemone mexicana, and Thevetia peruviana. In most of the cases, the principle of the plant responsible for the toxicity is unknown. There is limited information about the toxicity of medicinal plants used in Mexico, Central America, and the Caribbean. More toxicological studies are necessary to contribute information about the safe use of the medicinal plants cited in this review.

Suitability of soil bioengineering techniques in Central America: a case study in Nicaragua

Science.gov (United States)

Petrone, A.; Preti, F.

2008-10-01

In the last few years "D. I. A. F." (Department of Agriculture and Forestry Engineering of Florence University), has been testing the effectiveness of soil bioengineering techniques in Central America. The focus of the present study was to find out which native plants were most suited for soil bioengineering purposes, particularly in the realization of riverbank protection in Nicaragua. Furthermore, we have also been aiming at economic efficiency. These techniques are appropriate for sustainable watershed management especially in underdeveloped countries. Concerning the plants to be used we experimented four native species. Gliricidia Sepium, Cordia dentata and Jatropha curcas are suitable for soil bioengineering more than Bursera Simaruba. Economically speaking, the sustainability of such interventions in underdeveloped countries, has been shown by the evaluation of the cost of riverbank protection using vegetated crib-walls in Nicaragua compared to the cost in different contexts.

Method to Determine Appropriate Source Models of Large Earthquakes Including Tsunami Earthquakes for Tsunami Early Warning in Central America

Science.gov (United States)

Tanioka, Yuichiro; Miranda, Greyving Jose Arguello; Gusman, Aditya Riadi; Fujii, Yushiro

2017-08-01

Large earthquakes, such as the Mw 7.7 1992 Nicaragua earthquake, have occurred off the Pacific coasts of El Salvador and Nicaragua in Central America and have generated distractive tsunamis along these coasts. It is necessary to determine appropriate fault models before large tsunamis hit the coast. In this study, first, fault parameters were estimated from the W-phase inversion, and then an appropriate fault model was determined from the fault parameters and scaling relationships with a depth dependent rigidity. The method was tested for four large earthquakes, the 1992 Nicaragua tsunami earthquake (Mw7.7), the 2001 El Salvador earthquake (Mw7.7), the 2004 El Astillero earthquake (Mw7.0), and the 2012 El Salvador-Nicaragua earthquake (Mw7.3), which occurred off El Salvador and Nicaragua in Central America. The tsunami numerical simulations were carried out from the determined fault models. We found that the observed tsunami heights, run-up heights, and inundation areas were reasonably well explained by the computed ones. Therefore, our method for tsunami early warning purpose should work to estimate a fault model which reproduces tsunami heights near the coast of El Salvador and Nicaragua due to large earthquakes in the subduction zone.

International relations among Tom Thumbs: Taiwan as provider of aid Central America

Directory of Open Access Journals (Sweden)

Francisco Javier Haro Navejas

2007-06-01

Full Text Available This paper analyzes the Official Development Aid (AOD that has as its source Taiwan and as its destination Central America. It has three basic aims: Firstly, there is a huge bibliographic vacuum on the topic of these pages. Beginning filling it is an academic need. Even some intellectuals feel that they should lean against either Beijing or Taipei, that if they write on Taiwan they should defend or attack one of the contending parties. Here it is seen that a study close to objectivity is possible. Secondly, most of the research in International Relations has been focused on topics related with power itself or with just elements related with hard power. AOD is both hard and soft power, therefore this paper shades light to the dark side partially viewing international relations from a theoretical perspective were interactions help to construct identities and cooperation is an essential variable of world politics. Finally, it will be seen below that the Taiwanese cooperativeeconomic actions are helpful to the progress of poor parts of the Central American region and are helpful to create domestic markets with strong links with the world market deepening the economic integration both regional and global. Aid from Taiwan and some other countries, mainly through the transmission of know how, could be of assistance in surmounting huge troubles. Aid is vital because some of Central American’s problems are being exported mainly to México and the United States under the form, just to give an example, of Mara Salvatrucha gangs source of violence and drug trafficking. It is not meaningless to stress that Taiwanese ODA is by far not enough and is very small in the international context.

Chronic kidney disease of nontraditional etiology in Central America: a provisional epidemiologic case definition for surveillance and epidemiologic studies

Directory of Open Access Journals (Sweden)

Matthew Lozier

Full Text Available SYNOPSIS Over the last two decades, experts have reported a rising number of deaths caused by chronic kidney disease (CKD along the Pacific coast of Central America, from southern Mexico to Costa Rica. However, this specific disease is not associated with traditional causes of CKD, such as aging, diabetes, or hypertension. Rather, this disease is a chronic interstitial nephritis termed chronic kidney disease of nontraditional etiology (CKDnT. According to the Pan American Health Organization (PAHO mortality database, there are elevated rates of deaths related to kidney disease in many of these countries, with the highest rates being reported in El Salvador and Nicaragua. This condition has been identified in certain agricultural communities, predominantly among male farmworkers. Since CKD surveillance systems in Central America are under development or nonexistent, experts and governmental bodies have recommended creating standardized case definitions for surveillance purposes to monitor and characterize this epidemiological situation. A group of experts from Central American ministries of health, the U.S. Centers for Disease Control and Prevention (CDC, and PAHO held a workshop in Guatemala to discuss CKDnT epidemiologic case definitions. In this paper, we propose that CKD in general be identified by the standard definition internationally accepted and that a suspect case of CKDnT be defined as a person age < 60 years with CKD, without type 1 diabetes mellitus, hypertensive diseases, and other well-known causes of CKD. A probable case of CKDnT is defined as a suspect case with the same findings confirmed three or more months later.

What Use Is Population Genetics?

Science.gov (United States)

Charlesworth, Brian

2015-07-01

The Genetic Society of America's Thomas Hunt Morgan Medal is awarded to an individual GSA member for lifetime achievement in the field of genetics. For over 40 years, 2015 recipient Brian Charlesworth has been a leader in both theoretical and empirical evolutionary genetics, making substantial contributions to our understanding of how evolution acts on genetic variation. Some of the areas in which Charlesworth's research has been most influential are the evolution of sex chromosomes, transposable elements, deleterious mutations, sexual reproduction, and life history. He also developed the influential theory of background selection, whereby the recurrent elimination of deleterious mutations reduces variation at linked sites, providing a general explanation for the correlation between recombination rate and genetic variation. Copyright © 2015 by the Genetics Society of America.

Genetic diversity of neotropical Myotis (chiroptera: vespertilionidae with an emphasis on South American species.

Directory of Open Access Journals (Sweden)

Roxanne J Larsen

Full Text Available BACKGROUND: Cryptic morphological variation in the Chiropteran genus Myotis limits the understanding of species boundaries and species richness within the genus. Several authors have suggested that it is likely there are unrecognized species-level lineages of Myotis in the Neotropics. This study provides an assessment of the diversity in New World Myotis by analyzing cytochrome-b gene variation from an expansive sample ranging throughout North, Central, and South America. We provide baseline genetic data for researchers investigating phylogeographic and phylogenetic patterns of Myotis in these regions, with an emphasis on South America. METHODOLOGY AND PRINCIPAL FINDINGS: Cytochrome-b sequences were generated and phylogenetically analyzed from 215 specimens, providing DNA sequence data for the most species of New World Myotis to date. Based on genetic data in our sample, and on comparisons with available DNA sequence data from GenBank, we estimate the number of species-level genetic lineages in South America alone to be at least 18, rather than the 15 species currently recognized. CONCLUSIONS: Our findings provide evidence that the perception of lower species richness in South American Myotis is largely due to a combination of cryptic morphological variation and insufficient sampling coverage in genetic-based systematic studies. A more accurate assessment of the level of diversity and species richness in New World Myotis is not only helpful for delimiting species boundaries, but also for understanding evolutionary processes within this globally distributed bat genus.

Evidence for the exchange of blood parasites between North America and the Neotropics in blue-winged teal (Anas discors)

Science.gov (United States)

Ramey, Andy M.; Reed, John; Walther, Patrick; Link, Paul; Schmutz, Joel A.; Douglas, David C.; Stallknecht, David E.; Soos, Catherine

2016-01-01

Blue-winged teal (Anas discors) are abundant, small-bodied dabbling ducks that breed throughout the prairies of the northcentral USA and central Canada and that winter in the southern USA and northern Neotropics. Given the migratory tendencies of this species, it is plausible that blue-winged teal may disperse avian pathogens, such as parasites causing avian malaria, between spatially distant areas. To test the hypothesis that blue-winged teal play a role in the exchange of blood parasites between North America and areas further south, we collected information on migratory tendencies of this species and sampled birds at spatially distant areas during breeding and non-breeding periods to diagnose and genetically characterize parasitic infections. Using a combination of band recovery data, satellite telemetry, molecular diagnostics, and genetic analyses, we found evidence for (1) migratory connectivity of blue-winged teal between our sampling locations in the Canadian prairies and along the US Gulf Coast with areas throughout the northern Neotropics, (2) parasite acquisition at both breeding and non-breeding areas, (3) infection of blue-winged teal sampled in Canada and the USA withPlasmodium parasite lineages associated with the Neotropics, and (4) infection of blue-winged teal with parasites that were genetically related to those previously reported in waterfowl in both North America and South America. Collectively, our results suggest that blue-winged teal likely play a role in the dispersal of blood parasites between the Neotropics and North America, and therefore, the targeting of this species in surveillance programs for the early detection of Neotropical-origin avian pathogens in the USA may be informative.

Genetic structure of Octopus vulgaris (Cephalopoda, Octopodidae) in the central Mediterranean Sea inferred from the mitochondrial COIII gene.

Science.gov (United States)

Fadhlaoui-Zid, Karima; Knittweis, Leyla; Aurelle, Didier; Nafkha, Chaala; Ezzeddine, Soufia; Fiorentino, Fabio; Ghmati, Hisham; Ceriola, Luca; Jarboui, Othman; Maltagliati, Ferruccio

2012-01-01

The polymorphism of the mitochondrial gene cytochrome oxidase III was studied in the Mediterranean octopus, Octopus vulgaris Cuvier, 1797. A total of 202 specimens from seven sampling sites were analysed with the aim of elucidating patterns of genetic structure in the central Mediterranean Sea and to give an insight into the phylogeny of the Octopus genus. Phylogenetic analyses showed that individuals from the central Mediterranean belong to the O. vulgaris species whose limits should nevertheless be clarified. Concerning genetic structure, two high-frequency haplotypes were present in all locations. The overall genetic divergence (Φ(ST)=0.05, P<0.05) indicated a significant genetic structuring in the study area and an AMOVA highlighted a significant break between western and eastern Mediterranean basins (Φ(CT)=0.094, P<0.05). Possible explanations for the observed patterns of genetic structuring are discussed with reference to their relevance for fisheries management. Copyright © 2012. Published by Elsevier SAS.

Genetic Diversity in Jatropha curcas L. Assessed with SSR and SNP Markers

Directory of Open Access Journals (Sweden)

Juan M. Montes

2014-08-01

Full Text Available Jatropha curcas L. (jatropha is an undomesticated plant that has recently received great attention for its utilization in biofuel production, rehabilitation of wasteland, and rural development. Knowledge of genetic diversity and marker-trait associations is urgently needed for the design of breeding strategies. The main goal of this study was to assess the genetic structure and diversity in jatropha germplasm with co-dominant markers (Simple Sequence Repeats (SSR and Single Nucleotide Polymorphism (SNP in a diverse, worldwide, germplasm panel of 70 accessions. We found a high level of homozygosis in the germplasm that does not correspond to the purely outcrossing mating system assumed to be present in jatropha. We hypothesize that the prevalent mating system of jatropha comprise a high level of self-fertilization and that the outcrossing rate is low. Genetic diversity in accessions from Central America and Mexico was higher than in accession from Africa, Asia, and South America. We identified makers associated with the presence of phorbol esters. We think that the utilization of molecular markers in breeding of jatropha will significantly accelerate the development of improved cultivars.

Medicinal Plants from North and Central America and the Caribbean Considered Toxic for Humans: The Other Side of the Coin

OpenAIRE

Alonso-Castro, Angel Josabad; Domínguez, Fabiola; Ruiz-Padilla, Alan Joel; Campos-Xolalpa, Nimsi; Zapata-Morales, Juan Ramón; Carranza-Alvarez, Candy; Maldonado-Miranda, Juan Jose

2017-01-01

The consumption of medicinal plants has notably increased over the past two decades. People consider herbal products as safe because of their natural origin, without taking into consideration whether these plants contain a toxic principle. This represents a serious health problem. A bibliographic search was carried out using published scientific material on native plants from Mexico, Central America, and the Caribbean, which describe the ethnobotanical and toxicological information of medicin...

Genetic heterogeneity in supratentorial and infratentorial primitive neuroectodermal tumours of the central nervous system.

Science.gov (United States)

Inda, M M; Perot, C; Guillaud-Bataille, M; Danglot, G; Rey, J A; Bello, M J; Fan, X; Eberhart, C; Zazpe, I; Portillo, E; Tuñón, T; Martínez-Peñuela, J M; Bernheim, A; Castresana, J S

2005-12-01

Medulloblastoma (MB), a kind of infratentorial primitive neuroectodermal tumour (PNET), is the most frequent malignant brain tumour in childhood. In contrast, supratentorial PNET (sPNET) are very infrequent tumours, but they are histologically similar to MB, although they present a worse clinical outcome. We investigated the differences in genetic abnormalities between sPNET and MB. We analysed 20 central PNET (14 MB and six sPNET) by conventional comparative genomic hybridization (CGH) in order to determine whether a different genetic profile for each tumour exists. Isochromosome 17q was detected in four of the 14 MB cases, but not in any sPNET. Gains at 17q and 7 happened more frequently in MB, and those at 1q in sPNET. Losses at chromosome 10 were detected only in MB, while losses at 16p and 19p happened more frequently in sPNET. A new amplification site, on 4q12, was detected in two MB. Central PNET are a heterogeneous group of tumours from the genetic point of view. The present and previous data, together with further results from larger series, might contribute to the establishment of specific treatments for supratentorial and infratentorial PNET.

Method to Determine Appropriate Source Models of Large Earthquakes Including Tsunami Earthquakes for Tsunami Early Warning in Central America

OpenAIRE

Tanioka, Yuichiro; Miranda, Greyving Jose Arguello; Gusman, Aditya Riadi; Fujii, Yushiro

2017-01-01

Large earthquakes, such as the Mw 7.7 1992 Nicaragua earthquake, have occurred off the Pacific coasts of El Salvador and Nicaragua in Central America and have generated distractive tsunamis along these coasts. It is necessary to determine appropriate fault models before large tsunamis hit the coast. In this study, first, fault parameters were estimated from the W-phase inversion, and then an appropriate fault model was determined from the fault parameters and scaling relationships with a dept...

The use of genetics for the management of a recovering population: temporal assessment of migratory peregrine falcons in North America

Science.gov (United States)

Johnson, Jeff A.; Talbot, Sandra L.; Sage, George K.; Burnham, Kurt K.; Brown, Joseph W.; Maechtle, Tom L.; Seegar, William S.; Yates, Michael A.; Anderson, Bud; Mindell, David P.

2010-01-01

Background:Our ability to monitor populations or species that were once threatened or endangered and in the process of recovery is enhanced by using genetic methods to assess overall population stability and size over time. This can be accomplished most directly by obtaining genetic measures from temporally-spaced samples that reflect the overall stability of the population as given by changes in genetic diversity levels (allelic richness and heterozygosity), degree of population differentiation (FST and DEST), and effective population size (Ne). The primary goal of any recovery effort is to produce a long-term self-sustaining population, and these measures provide a metric by which we can gauge our progress and help make important management decisions. Methodology/Principal Findings:The peregrine falcon in North America (Falco peregrinus tundrius and anatum) was delisted in 1994 and 1999, respectively, and its abundance will be monitored by the species Recovery Team every three years until 2015. Although the United States Fish and Wildlife Service makes a distinction between tundrius and anatum subspecies, our genetic results based on eleven microsatellite loci, including those from Brown et al. (2007), suggest no differentiation and warrant delineation of a subspecies in its northern latitudinal distribution from Alaska through Canada into Greenland. Using temporal samples collected at Padre Island, Texas during migration (seven temporal time periods between 1985-2007), no significant differences in genetic diversity or significant population differentiation in allele frequencies between time periods were observed and were indistinguishable from those obtained from tundrius/anatum breeding locations throughout their northern distribution. Estimates of harmonic mean Ne were variable and imprecise, but always greater than 500 when employing multiple temporal genetic methods. These results, including those from simulations to assess the power of each method to

The Merida Initiative: Security-Surveillance Harmonization in Latin America

OpenAIRE

Nelson Arteaga Botello

2009-01-01

This work analyses the Merida Initiative, whose objective is to coordinate the information systems used against terrorism, organized crime, and drug and arms trafficking between the United States, Mexico and Central America. This implies the introduction of communication equipment, data bases and surveillance technology, which not only reinforces the security policies of the ‘western hemisphere’, but also consolidates and broadens the spaces of exception in Mexico and Central America, thus er...

All projects related to | Page 585 | IDRC - International Development ...

International Development Research Centre (IDRC) Digital Library (Canada)

Topic: Science and Technology, MEDICAL RESEARCH, HUMAN GENETICS, GENETIC ENGINEERING, BIOTECHNOLOGY. Region: Brazil, South America, China, Far East Asia, India, South Africa, North of Sahara, South of Sahara, North and Central America, Central Asia, South Asia, Egypt, Canada. Program: Networked ...

Unraveling the diversification history of grasshoppers belonging to the “Trimerotropis pallidipennis” (Oedipodinae: Acrididae species group: a hotspot of biodiversity in the Central Andes

Directory of Open Access Journals (Sweden)

Noelia Verónica Guzmán

2017-09-01

Full Text Available The Andean Mountain range has been recognized as one of the biodiversity hotspots of the world. The proposed mechanisms for such species diversification, among others, are due to the elevation processes occurring during the Miocene and the intensive glacial action during the Pleistocene. In this study we investigated the diversification history of the grasshopper Trimerotropis pallidipennis species complex which shows a particularly wide latitudinal and altitudinal distribution range across the northern, central and southern Andes in South America. Many genetic lineages of this complex have been so far discovered, making it an excellent model to investigate the role of the central Andes Mountains together with climatic fluctuations as drivers of speciation. Phylogenetics, biogeographic and molecular clock analyses using a multi-locus dataset revealed that in Peru there are at least two, and possibly four genetic lineages. Two different stocks originated from a common ancestor from North/Central America—would have dispersed toward southern latitudes favored by the closure of the Panama Isthmus giving rise to two lineages, the coastal and mountain lineages, which still coexist in Peru (i.e., T. pallidipennis and T. andeana. Subsequent vicariant and dispersal events continued the differentiation process, giving rise to three to six genetic lineages (i.e., clades detected in this study, which were geographically restricted to locations dispersed over the central Andes Mountains in South America. Our results provide another interesting example of “island diversification” motored by the topography plus unstable climatic conditions during the Pleistocene, pointing out the presence of a hotspot of diversification in the Andean region of Peru.

Genetic diversity of Trichomonas vaginalis clinical isolates from Henan province in central China.

Science.gov (United States)

Mao, Meng; Liu, Hui Li

2015-07-01

Trichomonas vaginalis is a flagellated protozoan parasite that infects the human urogenital tract, causing the most common non-viral, sexually transmitted disease worldwide. In this study, genetic variants of T. vaginalis were identified in Henan Province, China. Fragments of the small subunit of nuclear ribosomal RNA (18S rRNA) were amplified from 32 T. vaginalis isolates obtained from seven regions of Henan Province. Overall, 18 haplotypes were determined from the 18S rRNA sequences. Each sampled population and the total population displayed high haplotype diversity (Hd), accompanied by very low nucleotide diversity (Pi). In these molecular genetic variants, 91.58% genetic variation was derived from intra-regions. Phylogenetic analysis revealed no correlation between phylogeny and geographic distribution. Demographic analysis supported population expansion of T. vaginalis isolates from central China. Our findings showing moderate-to-high genetic variations in the 32 isolates of T. vaginalis provide useful knowledge for monitoring changes in parasite populations for the development of future control strategies.

Genetic structure of local populations of Lutzomyia longipalpis (Diptera: Psychodidae) in central Colombia.

Science.gov (United States)

Munstermann, L E; Morrison, A C; Ferro, C; Pardo, R; Torres, M

1998-01-01

Lutzomyia longipalpis (Lutz & Neiva), the sand fly vector of American visceral leishmaniasis in the New World tropics, has a broad but discontinuous geographical distribution from southern Mexico to Argentina. A baseline for population genetic structure and genetic variability for this species was obtained by analyzing 5 local, peridomestic populations at the approximate center of its distribution, the Magdalena River Valley of central Colombia. Three populations of L. longipalpis from El Callejón, a small rural community, were compared with 2 populations from neighboring areas 12 and 25 km distant for genetic variation at 15 isoenzyme loci. The mean heterozygosity ranged from 11 to 16%, with 1.2 to 2.3 alleles detected per locus. Nei's genetic distances among the populations were very low, ranging from 0.001 to 0.007. Gene flow estimates based on FST indicated high levels of gene flow among local L. longipalpis populations, with minimal population substructuring.

Phylogeography of screaming hairy armadillo Chaetophractus vellerosus: Successive disjunctions and extinctions due to cyclical climatic changes in southern South America.

Science.gov (United States)

Poljak, Sebastián; Ferreiro, Alejandro M; Chiappero, Marina B; Sánchez, Julieta; Gabrielli, Magalí; Lizarralde, Marta S

2018-01-01

Little is known about phylogeography of armadillo species native to southern South America. In this study we describe the phylogeography of the screaming hairy armadillo Chaetophractus vellerosus, discuss previous hypothesis about the origin of its disjunct distribution and propose an alternative one, based on novel information on genetic variability. Variation of partial sequences of mitochondrial DNA Control Region (CR) from 73 individuals from 23 localities were analyzed to carry out a phylogeographic analysis using neutrality tests, mismatch distribution, median-joining (MJ) network and paleontological records. We found 17 polymorphic sites resulting in 15 haplotypes. Two new geographic records that expand known distribution of the species are presented; one of them links the distributions of recently synonimized species C. nationi and C. vellerosus. Screaming hairy armadillo phylogeographic pattern can be addressed as category V of Avise: common widespread linages plus closely related lineages confined to one or a few nearby locales each. The older linages are distributed in the north-central area of the species distribution range in Argentina (i.e. ancestral area of distribution). C. vellerosus seems to be a low vagility species that expanded, and probably is expanding, its distribution range while presents signs of genetic structuring in central areas. To explain the disjunct distribution, a hypothesis of extinction of the species in intermediate areas due to quaternary climatic shift to more humid conditions was proposed. We offer an alternative explanation: long distance colonization, based on null genetic variability, paleontological record and evidence of alternance of cold/arid and temperate/humid climatic periods during the last million years in southern South America.

canada : tous les projets | Page 14 | CRDI - Centre de recherches ...

International Development Research Centre (IDRC) Digital Library (Canada)

Sujet: Science and Technology, MEDICAL RESEARCH, HUMAN GENETICS, GENETIC ENGINEERING, BIOTECHNOLOGY. Région: Brazil, South America, China, Far East Asia, India, South Africa, North of Sahara, South of Sahara, North and Central America, Central Asia, South Asia, Canada. Programme: Économies en ...

South Africa : tous les projets | Page 7 | CRDI - Centre de ...

International Development Research Centre (IDRC) Digital Library (Canada)

Sujet: Science and Technology, MEDICAL RESEARCH, HUMAN GENETICS, GENETIC ENGINEERING, BIOTECHNOLOGY. Région: Brazil, South America, China, Far East Asia, India, South Africa, North of Sahara, South of Sahara, North and Central America, Central Asia, South Asia, Canada. Programme: Économies en ...

: tous les projets | Page 544 | CRDI - Centre de recherches pour le ...

International Development Research Centre (IDRC) Digital Library (Canada)

Sujet: Science and Technology, MEDICAL RESEARCH, HUMAN GENETICS, GENETIC ENGINEERING, BIOTECHNOLOGY. Région: Brazil, South America, China, Far East Asia, India, South Africa, North of Sahara, South of Sahara, North and Central America, Central Asia, South Asia, Canada. Programme: Économies en ...

canada : tous les projets | Page 16 | CRDI - Centre de recherches ...

International Development Research Centre (IDRC) Digital Library (Canada)

Sujet: Science and Technology, MEDICAL RESEARCH, HUMAN GENETICS, GENETIC ENGINEERING, BIOTECHNOLOGY. Région: Brazil, South America, China, Far East Asia, India, South Africa, North of Sahara, South of Sahara, North and Central America, Central Asia, South Asia, Canada. Programme: Économies en ...

Chine : tous les projets | Page 7 | CRDI - Centre de recherches pour ...

International Development Research Centre (IDRC) Digital Library (Canada)

Sujet: Science and Technology, MEDICAL RESEARCH, HUMAN GENETICS, GENETIC ENGINEERING, BIOTECHNOLOGY. Région: Brazil, South America, China, Far East Asia, India, South Africa, North of Sahara, South of Sahara, North and Central America, Central Asia, South Asia, Canada. Programme: Économies en ...

Stomach cancer burden in Central and South America.

Science.gov (United States)

Sierra, Monica S; Cueva, Patricia; Bravo, Luis Eduardo; Forman, David

2016-09-01

Stomach cancer mortality rates in Central and South America (CSA) are among the highest in the world. We describe the current burden of stomach cancer in CSA. We obtained regional and national-level cancer incidence data from 48 population-based registries (13 countries) and nation-wide cancer deaths from WHO's mortality database (18 countries). We estimated world population age-standardized incidence (ASR) and mortality (ASMR) rates per 100,000 and estimated annual percent change to describe time trends. Stomach cancer was among the 5 most frequently diagnosed cancers and a leading cause of cancer mortality. Between CSA countries, incidence varied by 6-fold and mortality by 5-6-fold. Males had up to 3-times higher rates than females. From 2003 to 2007, the highest ASRs were in Chile, Costa Rica, Colombia, Ecuador, Brazil and Peru (males: 19.2-29.1, females: 9.7-15.1). The highest ASMRs were in Chilean, Costa Rican, Colombian and Guatemalan males (17.4-24.6) and in Guatemalan, Ecuadorian and Peruvian females (10.5-17.1). From 1997 to 2008, incidence declined by 4% per year in Brazil, Chile and Costa Rica; mortality declined by 3-4% in Costa Rica and Chile. 60-96% of all the cancer cases were unspecified in relation to gastric sub-site but, among those specified, non-cardia cancers occurred 2-13-times more frequently than cardia cancers. The variation in rates may reflect differences in the prevalence of Helicobacter pylori infection and other risk factors. High mortality may additionally reflect deficiencies in healthcare access. The high proportion of unspecified cases calls for improving cancer registration processes. Copyright © 2015 International Agency for Research on Cancer. Published by Elsevier Ltd.. All rights reserved.

Prostate cancer burden in Central and South America.

Science.gov (United States)

Sierra, Mónica S; Soerjomataram, Isabelle; Forman, David

2016-09-01

The incidence of prostate cancer has increased in Central and South America (CSA) in the last few decades. We describe the geographical patterns and trends of prostate cancer in CSA. We obtained regional and national-level cancer incidence data from 48 population-based registries in 13 countries and nation-wide cancer deaths from the WHO mortality database for 18 countries. We estimated world population age-standardized incidence (ASR) and mortality (ASMR) rates per 100,000 person-years for 2003-2007 and the estimated annual percent change (EAPC) to describe time trends. Prostate cancer was the most common cancer diagnosis and one of the leading causes of cancer deaths among males in most CSA countries. From 2003-2007, ASRs varied between countries (6-fold) and within countries (Brazil: 3-6-fold). French Guyana (147.1) and Brazil (91.4) had the highest ASRs whereas Mexico (28.9) and Cuba (24.3) had the lowest. ASMRs varied by 4-fold. Belize, Uruguay and Cuba (24.1-28.9) had the highest ASMRs while Peru, Nicaragua, and El Salvador (6.8-9.7) had the lowest. In Argentina, Brazil, Chile and Costa Rica prostate cancer incidence increased by 2.8-4.8% annually whereas mortality remained stable between 1997 and 2008. The geographic and temporal variation of prostate cancer rates observed in CSA may in part reflect differences in diagnostic and registration practices, healthcare access, treatment and death certification, and public awareness. The incidence of prostate cancer is expected to increase given recent early detection activities and increased public awareness; however, the impact of these factors on mortality remains to be elucidated. Copyright © 2016 International Agency for Research on Cancer. Published by Elsevier Ltd.. All rights reserved.

Diabetes in South and Central America: an update.

Science.gov (United States)

Aschner, Pablo; Aguilar-Salinas, Carlos; Aguirre, Loreto; Franco, Laercio; Gagliardino, Juan Jose; de Lapertosa, Sylvia Gorban; Seclen, Segundo; Vinocour, Mary

2014-02-01

The estimated population of the South and Central America (SACA) Region is 467.6 million and 64% is in the age range of 20-79 years but the population pyramid and age distribution are changing. The average prevalence of diabetes in the Region is 8.0% and is expected to reach 9.8% by the year 2035. Prevalence is much lower in rural settings than in urban and the differences attributed to lifestyle changes may be a target for intervention. The indigenous population is a particularly vulnerable group needing special attention. On average, 24% of the adult cases with diabetes are undiagnosed but in some countries this is still as high as 50%. Health expenditure due to diabetes in the Region is around 9% of the global total. Inadequate glycemic control, defined as HbA1c >7%, is a strong predictor of chronic complications which increase resource use in the Region and less than half of the patients enrolled in diabetes care programmes are at target. Fifty percent or more of the adult population is overweight/obese and around one third of the adult population has metabolic syndrome using regional cutoffs for waist circumference. The number of people with IGT is almost equal to those with diabetes presenting an additional challenge for prevention. Children with type 1 diabetes represent only 0.2% of the total population with diabetes but the incidence may be increasing. In many places they have limited access to insulin, and even when available, it is not used appropriately. The available epidemiological data provide the background to act in developing national diabetes programmes which integrate diabetes care with cardiovascular prevention and promote diabetes prevention as well. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Seismic swarms and fluid flow offshore Central America

Science.gov (United States)

Dzierma, Yvonne; Thorwart, Martin; Hensen, Christian; Rabbel, Wolfgang; Wolf, Florian

2010-05-01

Offshore Nicaragua and Northern Costa Rica, the Cocos Plate subducts beneath the Caribbean Plate, carrying with it a large amount of fluids and volatiles. While some of these are set free at great depth beneath the volcanic arc, causing the extremely high water content observed in Nicaraguan mafic magmas (Carr et al., 2003; Kutterolf et al., 2007), some early dehydration reactions already release fluids from the subducting plate underneath the continental slope. Unlike in accretionary margins, where these fluids migrate up along the decollement towards the deformation front, fluid release at erosional margins seems to occur through fractures in the overriding plate (Ranero et al., 2008). Fluid seeps in this region have be observed at seafloor mounds, appearing as side-scan sonar backscatter anomalies or revealed by the presence of chemosynthetic communities (Sahling et al., 2008). In the framework of the General Research Area SFB 574 "Volatiles and Fluids in Subduction Zones", a network of 20 ocean-bottom-stations was deployed offshore Sta Elena Peninsula, Northern Costa Rica, from December 2005 to June 2006. Several distinct swarms of small earthquakes were observed at the seismic stations, which occurred clustered over a time period of several days and have very similar seismic waveforms. Since a correlation of fluid-release sites with the occurrence of sporadic seismic swarms would indicate that fluid migration and fracturing is the mechanism responsible for triggering the earthquake swarms, the events are re-analysed by double-difference localisation to enhance the resolution of the earthquake locations. The results are then considered to estimate the migration velocity and direction and compare the localisations with the known mound sites. Carr, M., Feigenson, M. D., Patino, L. C., and Walker, J. A., 2003: Volcanism and geochemistry in Central America: Progress and problems, in Eiler, J. (ed.), Inside the subduction factory, pp. 153-179, American Geophysical

Mapping Mangrove Density from Rapideye Data in Central America

Science.gov (United States)

Son, Nguyen-Thanh; Chen, Chi-Farn; Chen, Cheng-Ru

2017-06-01

Mangrove forests provide a wide range of socioeconomic and ecological services for coastal communities. Extensive aquaculture development of mangrove waters in many developing countries has constantly ignored services of mangrove ecosystems, leading to unintended environmental consequences. Monitoring the current status and distribution of mangrove forests is deemed important for evaluating forest management strategies. This study aims to delineate the density distribution of mangrove forests in the Gulf of Fonseca, Central America with Rapideye data using the support vector machines (SVM). The data collected in 2012 for density classification of mangrove forests were processed based on four different band combination schemes: scheme-1 (bands 1-3, 5 excluding the red-edge band 4), scheme-2 (bands 1-5), scheme-3 (bands 1-3, 5 incorporating with the normalized difference vegetation index, NDVI), and scheme-4 (bands 1-3, 5 incorporating with the normalized difference red-edge index, NDRI). We also hypothesized if the obvious contribution of Rapideye red-edge band could improve the classification results. Three main steps of data processing were employed: (1), data pre-processing, (2) image classification, and (3) accuracy assessment to evaluate the contribution of red-edge band in terms of the accuracy of classification results across these four schemes. The classification maps compared with the ground reference data indicated the slightly higher accuracy level observed for schemes 2 and 4. The overall accuracies and Kappa coefficients were 97% and 0.95 for scheme-2 and 96.9% and 0.95 for scheme-4, respectively.

Echinococcus multilocularis in North America: the great unknown

Science.gov (United States)

Massolo, Alessandro; Liccioli, Stefano; Budke, Christine; Klein, Claudia

2014-01-01

Over the last decade, studies have begun to shed light on the distribution and genetic characterization of Echinococcus multilocularis, the causative agent of alveolar echinococcosis (AE), in North America. Recent findings indicate that the parasite is likely expanding its range in the central region of the United States and Canada and that invasions of European strains might have occurred. In our review, we present the available data on E. multilocularis infections in wild and domestic animals and humans in North America and emphasize the lack of knowledge on the distribution of the parasite in wild and domestic hosts. Furthermore, we stress the need to better understand the complexity of host communities and their roles in shaping the transmission and distribution of the parasite. We hypothesize that a lack of knowledge about AE by North American physicians might result in the misdiagnosis of cases and an underestimation of disease incidence. The endemic presence of the parasite in urban areas and a recent human case in Alberta, Canada, suggest that the scientific community may need to reconsider the local public health risks, re-assess past cases that might have been overlooked and increase surveillance efforts to identify new cases of human AE. PMID:25531581

Holocene re-colonisation, central-marginal distribution and habitat specialisation shape population genetic patterns within an Atlantic European grass species.

Science.gov (United States)

Harter, D E V; Jentsch, A; Durka, W

2015-05-01

Corynephorus canescens (L.) P.Beauv. is an outbreeding, short-lived and wind-dispersed grass species, highly specialised on scattered and disturbance-dependent habitats of open sandy sites. Its distribution ranges from the Iberian Peninsula over Atlantic regions of Western and Central Europe, but excludes the two other classical European glacial refuge regions on the Apennine and Balkan Peninsulas. To investigate genetic patterns of this uncommon combination of ecological and biogeographic species characteristics, we analysed AFLP variation among 49 populations throughout the European distribution range, expecting (i) patterns of SW European glacial refugia and post-glacial expansion to the NE; (ii) decreasing genetic diversity from central to marginal populations; and (iii) interacting effects of high gene flow and disturbance-driven genetic drift. Decreasing genetic diversity from SW to NE and distinct gene pool clustering imply refugia on the Iberian Peninsula and in western France, from where range expansion originated towards the NE. High genetic diversity within and moderate genetic differentiation among populations, and a significant pattern of isolation-by-distance indicate a gene flow drift equilibrium within C. canescens, probably due to its restriction to scattered and dynamic habitats and limited dispersal distances. These features, as well as the re-colonisation history, were found to affect genetic diversity gradients from central to marginal populations. Our study emphasises the need for including the specific ecology into analyses of species (re-)colonisation histories and range centre-margin analyses. To account for discontinuous distributions, new indices of marginality were tested for their suitability in studies of centre-periphery gradients. © 2014 German Botanical Society and The Royal Botanical Society of the Netherlands.

The Spanish decentralised international cooperation in Central America in the area of municipalism and decentralisation

Directory of Open Access Journals (Sweden)

Mariana Haedo

2005-05-01

Full Text Available In an attempt to link the international dimension with the local one, this article lays out an approach to the situation of Spanish decentralised international cooperation in the area of municipalism and decentralisation in the countries of Central America. In the firstplace, it offers a characterisation of the current state of Spanish decentralised cooperation in order to thus frame the cooperation actions carried out by the Barcelona Provincial Council; the UIM (Unión Iberoamericana de Municipios together with CEMCI (Centro de Estudios Municipales y de Cooperación Internacional; and the Confederación de Fondos de Cooperación y Solidaridad. Finally, it describes bankruptcies and it recovers some of the achievements ofthis kind of cooperation specifically in reference to the field of municipalism.

Distribution and Genetic Structure of Fucus distichus Linnaeus 1953 (formerly F. gardneri within Central San Francisco Bay

Directory of Open Access Journals (Sweden)

Stephen G. Whitaker

2017-09-01

Full Text Available doi: https://doi.org/10.15447/sfews.2017v15iss3art4Fucus distichus, a rockweed common to the mid-intertidal shoreline within the San Francisco Estuary (previously known as F. gardneri, was injured during the Cosco Busan oil spill in November 2007 and subsequent clean-up actions. Restoration planning activities are underway to help recover F. distichus at sites within central San Francisco Bay where damage occurred. As a first step, we conducted shoreline surveys during the summers of 2012–2013 to map the occurrence of this rockweed. Of the 151.73 km of rocky shoreline within the central bay, F. distichus covered 32.16 km of shoreline. The alga generally occurred in narrow bands but formed expansive beds at locations with natural, flat bedrock benches. We also observed F. distichus on artificial substrata such as seawalls and riprap, but not on pilings. Samples of F. distichus from 11 sites throughout the central / east San Francisco Bay were genetically analyzed (microsatellite genotyping. The populations analyzed (1 had low genetic diversity, (2 the frequency of homozygotes was higher than expected (suggesting high inbreeding, and (3 also displayed geographic population structure, in part driven by very small differences in the midst of extremely low within-population genetic diversity. However, these genetic data do not raise concerns for restoration methods in terms of choosing donor populations and mixing F. distichus from different sites within the central bay. The choice of donor populations should be based on practical criteria for effective restoration; individuals will nonetheless be taken from locations as nearby to donor sites as possible. Various locations throughout the central San Francisco Bay are composed of cobble or small riprap that are populated with F. distichus, which could provide efficient means of translocating rockweed for future restoration activities.

Fungus Causing White-Nose Syndrome in Bats Accumulates Genetic Variability in North America with No Sign of Recombination.

Science.gov (United States)

Trivedi, Jigar; Lachapelle, Josianne; Vanderwolf, Karen J; Misra, Vikram; Willis, Craig K R; Ratcliffe, John M; Ness, Rob W; Anderson, James B; Kohn, Linda M

2017-01-01

Emerging fungal diseases of wildlife are on the rise worldwide, and the white-nose syndrome (WNS) epidemic in North American bats is a catastrophic example. The causal agent of WNS is a single clone of the fungus Pseudogymnoascus destructans . Early evolutionary change in this clonal population has major implications for disease ecology and conservation. Accumulation of variation in the fungus through mutation, and shuffling of variation through recombination, could affect the virulence and transmissibility of the fungus and the durability of what appears to be resistance arising in some bat populations. Our genome-wide analysis shows that the clonal population of P. destructans has expanded in size from a single genotype, has begun to accumulate variation through mutation, and presents no evidence as yet of genetic exchange among individuals. IMPORTANCE Since its discovery in 2006, the emerging infectious disease known as white-nose syndrome has killed millions of bats in North America, making it one of the most devastating wildlife epidemics in recorded history. We demonstrate that there has been as yet only spontaneous mutation across the North American population of P. destructans , and we find no indication of recombination. Thus, selective forces, which might otherwise impact pathogenic virulence, have so far had essentially no genetic variation on which to act. Our study confirmed the time of origin for the first and, thus far, only introduction of P. destructans to North America. This system provides an unprecedented opportunity to follow the evolution of a host-pathogen interaction unfolding in real time.

Comparative genetic diversity in a sample of pony breeds from the U.K. and North America: a case study in the conservation of global genetic resources.

Science.gov (United States)

Winton, Clare L; Plante, Yves; Hind, Pamela; McMahon, Robert; Hegarty, Matthew J; McEwan, Neil R; Davies-Morel, Mina C G; Morgan, Charly M; Powell, Wayne; Nash, Deborah M

2015-08-01

Most species exist as subdivided ex situ daughter population(s) derived from a single original group of individuals. Such subdivision occurs for many reasons both natural and manmade. Traditional British and Irish pony breeds were introduced to North America (U.S.A. and Canada) within the last 150 years, and subsequently equivalent breed societies were established. We have analyzed selected U.K. and North American equivalent pony populations as a case study for understanding the relationship between putative source and derived subpopulations. Diversity was measured using mitochondrial DNA and a panel of microsatellite markers. Genetic signatures differed between the North American subpopulations according to historical management processes. Founder effect and stochastic drift was apparent, particularly pronounced in some breeds, with evidence of admixture of imported mares of different North American breeds. This demonstrates the importance of analysis of subpopulations to facilitate understanding the genetic effects of past management practices and to lead to informed future conservation strategies.

Geology of gemstone deposit Ugljarevats (Central Serbia) and contributions to genetic model

International Nuclear Information System (INIS)

Kureshevicj, Lidija; Vushovicj, Olivera; Delicj-Nikolicj, Ivana

2017-01-01

Silica gemstone deposit Ugljarevats is situated within the ophiolite sequence of the Vardar zone central deep fault. Genetic processes of this deposit are connected to the Neogene calc-alkaline magmatic activity of the Vardar zone and hydrothermal activity triggered by it. Based on surface occurrences of listwenitized serpentinite containing silica mineralization, it can be inferred that the ore body is an elongated oval stock. Within the stock of hydrothermally altered serpentinite, the gemstone mineralization occurs as veins, stock works and irregular bodies. Present gemstone types include chalcedony varieties (jasper, colourless and greenish chalcedony, carnelian and sard) and opal (opalized serpentinite). Homogenous pieces are very rare. Most often, various types of silica are intimately intermixed and combined. The mineralization has formed in two distinct hydrothermal phases, apparently in close time succession. Jasper and coloured chalcedony (and rare magnesite) are the products of the first phase of hydro- thermal activity, while the colourless chalcedony is formed in the second phase. Newly discovered type of silica vein with central-symmetrical parallel banding gives new contributions to a genetic model, proving the precipitation process and its products are unpredictably changeable, heterogeneous and depending on the evolution of the local environment physico-chemical conditions, notably the contents of impurities and system's openness degree. (author)

First record of the invasive Asian fish tapeworm Bothriocephalus acheilognathi in Honduras, Central America.

Science.gov (United States)

Salgado-Maldonado, Guillermo; Matamoros, Wilfredo A; Kreiser, Brian R; Caspeta-Mandujano, Juan Manuel; Mendoza-Franco, Edgar F

2015-01-01

This paper provides the first report of the invasive Asian fish tapeworm, Bothriocephalus acheilognathi Yamaguti, 1934, in Honduras. The cestode was found in Profundulus portillorum (Cyprinodontiformes: Profundulidae), which represents a new host record, and which is a member of a genus faced with a variety of conservation challenges, now potentially complicated by the presence of this pathogenic cestode. Nearly complete sequence data from the ITS-1 5.8S and ITS-2 regions corroborate the determination based on morphological characteristics. Several species of carp were introduced to Honduras for aquaculture purposes in the early 1980s and the presence of the Asian fish tapeworm in Honduras may be related to these introductions. In addition, this report documents the currently known geographical distribution of this parasite in Central America, first recorded from Panamá and now from Honduras. © G. Salgado-Maldonado et al., published by EDP Sciences, 2015.

Mid-term evaluation of the NRECA (National Rural Electric Cooperative Association) Central America Rural Electrification Support Program (CARES)

Energy Technology Data Exchange (ETDEWEB)

Perlack, R.D. (Oak Ridge National Lab., TN (USA)); Jones, H.G. (Oak Ridge Associated Universities, Inc., TN (USA)); Garcia, A. III (Texas A and M Univ., College Station, TX (USA). Dept. of Agricultural Engineering); Flores, E. (Flores (Edgar), Guatemala City (Guatemala))

1990-09-01

Oak Ridge National Laboratory was requested by the Regional Office for Central America and Panama to conduct a mid-term evaluation of the Cares Project, which is being implemented by the National Rural Electric Cooperative Association. This evaluation was conducted over a three week period by a four person team. Overall, the project has had numerous successes and is highly valued by local counterpart utilities and USAID Missions. Notwithstanding the significant results of the project, changes can be made in certain operating procedures and in the direction of some programmatic activities that can lead to an even more effective project.

From Forgotten Area to Platform of Expansion. Central America in the Cartographic Representations and English Naval Projects (1680-1742

Directory of Open Access Journals (Sweden)

Guadalupe Pinzón Ríos

2018-05-01

Full Text Available The aim of this article is to analyze how the English became interested in Central America and planned to use it as a platform to extend their naval activities from the Atlantic to the Pacific. They revealed their intentions in their accounts of their voyages and in their maps. Those accounts and maps became instruments of power to justify their advances, and by means of them, they tried to make their presence permanent. Is important to analyze this process because the English used this method again in other areas.

Is violence associated with increased risk behavior among MSM? Evidence from a population-based survey conducted across nine cities in Central America.

Science.gov (United States)

Wheeler, Jennifer; Anfinson, Katherine; Valvert, Dennis; Lungo, Susana

2014-01-01

There is a dearth of research examining the linkages between violence and HIV risk behavior among men who have sex with men (MSM), including those who identify as transgender women (TW), particularly in Central America where violence is widespread. In this paper, we use population-based survey results to independently examine the correlations between physical, emotional and sexual violence and HIV risk behavior among MSM populations in five countries in Central America. As part of USAID's Combination Prevention for HIV program in Central America, PASMO conducted population based surveys using respondent-driven sampling (RDS) in nine cities in Guatemala, El Salvador, Nicaragua, Costa Rica, and Panama. Initial seeds were recruited using the following criteria: individuals who represented subgroups of MSM by self-identification (homosexual vs. heterosexual or bisexual vs. transgender), social economic strata, and by sex work practices. This study examines the association between violence and 1) HIV risk behaviors relevant to the study populations; 2) protective behaviors; and 3) reported STIs. Individualized RDS estimator weights for each outcome variable were calculated using RDSAT software, and logistic regression analysis was used to determine associations between different forms of violence and the outcome variables. MSM who experienced physical violence were more likely to be engaged in transactional sex (OR: 1.76 [1.42-2.18]), have multiple partners in the past 30 days (OR: 1.37 [1.09-1.71]), and have engaged in sex under the influence of alcohol or drugs (OR: 1.51 [1.24-1.83]). Both physical violence and psychological/verbal violence were also associated with reporting STI symptoms or diagnosis within the past 12 months (OR: 1.72 [1.34-2.21] and 1.80 [1.45-2.23]). The effects of violence on the outcomes were observed after controlling for other risk factors. Transgender women were 3.9 times more likely to report engaging in transactional sex. Respondents who

Is violence associated with increased risk behavior among MSM? Evidence from a population-based survey conducted across nine cities in Central America

Directory of Open Access Journals (Sweden)

Jennifer Wheeler

2014-10-01

Full Text Available Background/Objective: There is a dearth of research examining the linkages between violence and HIV risk behavior among men who have sex with men (MSM, including those who identify as transgender women (TW, particularly in Central America where violence is widespread. In this paper, we use population-based survey results to independently examine the correlations between physical, emotional and sexual violence and HIV risk behavior among MSM populations in five countries in Central America. Design: As part of USAID's Combination Prevention for HIV program in Central America, PASMO conducted population based surveys using respondent-driven sampling (RDS in nine cities in Guatemala, El Salvador, Nicaragua, Costa Rica, and Panama. Initial seeds were recruited using the following criteria: individuals who represented subgroups of MSM by self-identification (homosexual vs. heterosexual or bisexual vs. transgender, social economic strata, and by sex work practices. This study examines the association between violence and 1 HIV risk behaviors relevant to the study populations; 2 protective behaviors; and 3 reported STIs. Individualized RDS estimator weights for each outcome variable were calculated using RDSAT software, and logistic regression analysis was used to determine associations between different forms of violence and the outcome variables. Results: MSM who experienced physical violence were more likely to be engaged in transactional sex (OR: 1.76 [1.42–2.18], have multiple partners in the past 30 days (OR: 1.37 [1.09–1.71], and have engaged in sex under the influence of alcohol or drugs (OR: 1.51 [1.24–1.83]. Both physical violence and psychological/verbal violence were also associated with reporting STI symptoms or diagnosis within the past 12 months (OR: 1.72 [1.34–2.21] and 1.80 [1.45–2.23]. The effects of violence on the outcomes were observed after controlling for other risk factors. Transgender women were 3.9 times more likely

First record of giant anteater (xenarthra, myrmecophagidae) in north america.

Science.gov (United States)

Shaw, C A; McDonald, H G

1987-04-10

A right metacarpal III represents the first North American record of the giant anteater (Myrmecophaga tridactyla). Recovered in northwestern Sonora, Mexico, with a rich vertebrate fauna of early Pleistocene (Irvingtonian) age, it belongs to a cohort of large mammals that dispersed from South America to North America along a savanna corridor. Presumably habitat and climatic changes have subsequently driven this mammalian family more than 3000 kilometers back into Central America from its former expansion into temperate North America.

Phylogeography of screaming hairy armadillo Chaetophractus vellerosus: Successive disjunctions and extinctions due to cyclical climatic changes in southern South America.

Directory of Open Access Journals (Sweden)

Sebastián Poljak

Full Text Available Little is known about phylogeography of armadillo species native to southern South America. In this study we describe the phylogeography of the screaming hairy armadillo Chaetophractus vellerosus, discuss previous hypothesis about the origin of its disjunct distribution and propose an alternative one, based on novel information on genetic variability. Variation of partial sequences of mitochondrial DNA Control Region (CR from 73 individuals from 23 localities were analyzed to carry out a phylogeographic analysis using neutrality tests, mismatch distribution, median-joining (MJ network and paleontological records. We found 17 polymorphic sites resulting in 15 haplotypes. Two new geographic records that expand known distribution of the species are presented; one of them links the distributions of recently synonimized species C. nationi and C. vellerosus. Screaming hairy armadillo phylogeographic pattern can be addressed as category V of Avise: common widespread linages plus closely related lineages confined to one or a few nearby locales each. The older linages are distributed in the north-central area of the species distribution range in Argentina (i.e. ancestral area of distribution. C. vellerosus seems to be a low vagility species that expanded, and probably is expanding, its distribution range while presents signs of genetic structuring in central areas. To explain the disjunct distribution, a hypothesis of extinction of the species in intermediate areas due to quaternary climatic shift to more humid conditions was proposed. We offer an alternative explanation: long distance colonization, based on null genetic variability, paleontological record and evidence of alternance of cold/arid and temperate/humid climatic periods during the last million years in southern South America.

Discordant genetic diversity and geographic patterns between Crassicutis cichlasomae (Digenea: Apocreadiidae) and its cichlid host, "Cichlasoma" urophthalmus (Osteichthyes: Cichlidae), in Middle-America.

Science.gov (United States)

Razo-Mendivil, Ulises; Vázquez-Domínguez, Ella; de León, Gerardo Pérez-Ponce

2013-12-01

Genetic analyses of hosts and their parasites are key to understand the evolutionary patterns and processes that have shaped host-parasite associations. We evaluated the genetic structure of the digenean Crassicutis cichlasomae and its most common host, the Mayan cichlid "Cichlasoma" urophthalmus, encompassing most of their geographical range in Middle-America (river basins in southeastern Mexico, Belize, and Guatemala together with the Yucatan Peninsula). Genetic diversity and structure analyses were done based on 167 cytochrome c oxidase subunit 1 sequences (330 bp) for C. cichlasomae from 21 populations and 161 cytochrome b sequences (599 bp) for "C." urophthalmus from 26 populations. Analyses performed included phylogenetic tree estimation under Bayesian inference and maximum likelihood analysis, genetic diversity, distance and structure estimates, haplotype networks, and demographic evaluations. Crassicutis cichlasomae showed high genetic diversity values and genetic structuring, corresponding with 4 groups clearly differentiated and highly divergent. Conversely, "C." urophthalmus showed low levels of genetic diversity and genetic differentiation, defined as 2 groups with low divergence and with no correspondence with geographical distribution. Our results show that species of cichlids parasitized by C. cichlasomae other than "C." urophthalmus, along with multiple colonization events and subsequent isolation in different basins, are likely factors that shaped the genetic structure of the parasite. Meanwhile, historical long-distance dispersal and drought periods during the Holocene, with significant population size reductions and fragmentations, are factors that could have shaped the genetic structure of the Mayan cichlid.

Outlook for modern cooking energy access in Central America

Science.gov (United States)

2018-01-01

The Central American nations of Guatemala, Honduras and Nicaragua are among the poorest in the Americas. While the fraction of population dependent on solid fuels has declined in these nations over the last 25 years, the number of people using them has risen. Here, we first assess current patterns of cooking energy use in these nations. We then apply a discrete model of household cooking choices and demand to simulate future pathways of clean cooking uptake and the outlook for achieving target 7.1 of the Sustainable Development Goals (SDG), which aims to ensure universal access to affordable, reliable and modern energy services by 2030. We find that by 2030, ensuing income growth is likely to enable 90% of urban populations in these nations to switch to using modern cooking energy services. However, without supporting policies, between 40% to 50% of rural Guatemalans and Hondurans, while over two-thirds of rural Nicaraguans, are likely to find clean fuels or stoves unaffordable in 2030. A targeted subsidy on modern fuels, like liquid petroleum gas (LPG), is the most effective policy mechanism we studied that could provide such support. A 50% subsidy policy on LPG targeted to the rural and urban poor population could, by 2030, make cooking with LPG affordable to an additional 7.3 million people in these countries. We estimate that such a policy would cost about $250 million per year and would have negligible greenhouse gas emissions impacts. Such a policy could also have significant health benefits, preventing about 8,890 premature deaths annually from reduced exposure to cooking-related household pollution in 2030. PMID:29883457

Health care providers and human trafficking: What do they know, what do they need to know? Findings from the middle East, the Caribbean, and Central America

NARCIS (Netherlands)

Viergever, R.F.; West, H.; Borland, R.; Zimmerman, C.

2015-01-01

BACKGROUND: Human trafficking is a crime that commonly results in acute and chronic physical and psychological harm. To foster more informed health sector responses to human trafficking, training sessions for health care providers were developed and pilot-tested in the Middle East, Central America,

Medicinal Plants from Mexico, Central America, and the Caribbean Used as Immunostimulants

Science.gov (United States)

Juárez-Vázquez, María del Carmen; Campos-Xolalpa, Nimsi

2016-01-01

A literature review was undertaken by analyzing distinguished books, undergraduate and postgraduate theses, and peer-reviewed scientific articles and by consulting worldwide accepted scientific databases, such as SCOPUS, Web of Science, SCIELO, Medline, and Google Scholar. Medicinal plants used as immunostimulants were classified into two categories: (1) plants with pharmacological studies and (2) plants without pharmacological research. Medicinal plants with pharmacological studies of their immunostimulatory properties were subclassified into four groups as follows: (a) plant extracts evaluated for in vitro effects, (b) plant extracts with documented in vivo effects, (c) active compounds tested on in vitro studies, and (d) active compounds assayed in animal models. Pharmacological studies have been conducted on 29 of the plants, including extracts and compounds, whereas 75 plants lack pharmacological studies regarding their immunostimulatory activity. Medicinal plants were experimentally studied in vitro (19 plants) and in vivo (8 plants). A total of 12 compounds isolated from medicinal plants used as immunostimulants have been tested using in vitro (11 compounds) and in vivo (2 compounds) assays. This review clearly indicates the need to perform scientific studies with medicinal flora from Mexico, Central America, and the Caribbean, to obtain new immunostimulatory agents. PMID:27042188

Medicinal Plants from Mexico, Central America, and the Caribbean Used as Immunostimulants

Directory of Open Access Journals (Sweden)

Angel Josabad Alonso-Castro

2016-01-01

Full Text Available A literature review was undertaken by analyzing distinguished books, undergraduate and postgraduate theses, and peer-reviewed scientific articles and by consulting worldwide accepted scientific databases, such as SCOPUS, Web of Science, SCIELO, Medline, and Google Scholar. Medicinal plants used as immunostimulants were classified into two categories: (1 plants with pharmacological studies and (2 plants without pharmacological research. Medicinal plants with pharmacological studies of their immunostimulatory properties were subclassified into four groups as follows: (a plant extracts evaluated for in vitro effects, (b plant extracts with documented in vivo effects, (c active compounds tested on in vitro studies, and (d active compounds assayed in animal models. Pharmacological studies have been conducted on 29 of the plants, including extracts and compounds, whereas 75 plants lack pharmacological studies regarding their immunostimulatory activity. Medicinal plants were experimentally studied in vitro (19 plants and in vivo (8 plants. A total of 12 compounds isolated from medicinal plants used as immunostimulants have been tested using in vitro (11 compounds and in vivo (2 compounds assays. This review clearly indicates the need to perform scientific studies with medicinal flora from Mexico, Central America, and the Caribbean, to obtain new immunostimulatory agents.

Genetic Structuration, Demography and Evolutionary History of Mycobacterium tuberculosis LAM9 Sublineage in the Americas as Two Distinct Subpopulations Revealed by Bayesian Analyses

Science.gov (United States)

Reynaud, Yann; Millet, Julie; Rastogi, Nalin

2015-01-01

Tuberculosis (TB) remains broadly present in the Americas despite intense global efforts for its control and elimination. Starting from a large dataset comprising spoligotyping (n = 21183 isolates) and 12-loci MIRU-VNTRs data (n = 4022 isolates) from a total of 31 countries of the Americas (data extracted from the SITVIT2 database), this study aimed to get an overview of lineages circulating in the Americas. A total of 17119 (80.8%) strains belonged to the Euro-American lineage 4, among which the most predominant genotypic family belonged to the Latin American and Mediterranean (LAM) lineage (n = 6386, 30.1% of strains). By combining classical phylogenetic analyses and Bayesian approaches, this study revealed for the first time a clear genetic structuration of LAM9 sublineage into two subpopulations named LAM9C1 and LAM9C2, with distinct genetic characteristics. LAM9C1 was predominant in Chile, Colombia and USA, while LAM9C2 was predominant in Brazil, Dominican Republic, Guadeloupe and French Guiana. Globally, LAM9C2 was characterized by higher allelic richness as compared to LAM9C1 isolates. Moreover, LAM9C2 sublineage appeared to expand close to twenty times more than LAM9C1 and showed older traces of expansion. Interestingly, a significant proportion of LAM9C2 isolates presented typical signature of ancestral LAM-RDRio MIRU-VNTR type (224226153321). Further studies based on Whole Genome Sequencing of LAM strains will provide the needed resolution to decipher the biogeographical structure and evolutionary history of this successful family. PMID:26517715

Occupational health in Central America.

Science.gov (United States)

Wesseling, Catharina; Aragón, Aurora; Morgado, Hugo; Elgstrand, Kaj; Hogstedt, Christer; Partanen, Timo

2002-01-01

The 12.4 million economically active population (EAP) of the seven Central American countries includes a large informal sector. Social security covers only 14-60%. No surveillance of occupational safety and health (OSH) hazards or accidents exists. Extrapolating the incidence of occupational accidents among insured Costa Rican workers to the Central American EAP yields two million accidents yearly, still a gross underestimate. Occupational diseases are underreported, misdiagnosed, and not recognized as such. A number of regional OSH programs aim at modernization of the labor administrations and address the formal sector, in particular textile maquila, in connection with free trade agreements. The weak role of the ministries of health is expected to strengthen under the Pan American Health Organization OSH program. Employers largely influence new policies. Workers' influence on OSH policies has been weak, with only about 10% unionization rate and scarce resources and OSH knowledge. Informal workers, however, are getting organized. OSH research is underdeveloped and not linked to policy making. Construction, agriculture, and general un/underemployment are considered priorities for intervention. The informal sector needs to be included in national and regional OSH policies. Regional collaboration and international development support are of strategic importance to achieve sustainable improvement in OSH.

Central Bank autonomy in Europe and Latin America: analysis of differences and applications Autonomía de la banca central en Europa y América Latina

Directory of Open Access Journals (Sweden)

Rollinat Robert

1996-06-01

Full Text Available This article makes a comparative analysis of the experiences of the independent central bank in Latin America and Europe. After reviewing the problems and theories of central bank autonomy, it studies the recent evolution of the Latin American central bank in comparison with the European central bank, high lights the perverse effects of the reforms, and shows that their objective is more the stability of the financial system than the stability of prices. Finally, it describes the tests to which the new Latin American central banks have been subjected and the effects on their credibility. It concludes that these entities have had to correct and pay for the incoherences and errors of the market, and that their independence or autonomy depends on their continuing to ful fill this role, not only for economíc or monetary reasons but for the needs of political and social democracy.Este artículo hace un análisis comparativo de las experiencias de la banca central independiente en América Latina y Europa. Después de revisar los problemas y las teorías de la autonompia de los bancos centrales, estudia la reciente evolución de la banca central latinoamericana en comparación con la europea, destaca los efectos perversos de estas reformas u muestra que sus objetivo es más la estabilidad del sistema financiero que la de los precios. Finalmente, describe las pruebas a que han sido sometidos los nuevos bancos centrales latinomaericanos y los efectos de sus credibilidad. Concluye que estas entidades han tenido que corregir y pagar las incoherencias y los errrores del mercado, y que su 'independencia' o autonomía depende de que sigan cumpliendo con ese papel no sólo por razones económicas o monetarias sino por las necesidades de la democracia política y social.

Genetic variation and phylogenetic relationship analysis of Jatropha curcas L. inferred from nrDNA ITS sequences.

Science.gov (United States)

Guo, Guo-Ye; Chen, Fang; Shi, Xiao-Dong; Tian, Yin-Shuai; Yu, Mao-Qun; Han, Xue-Qin; Yuan, Li-Chun; Zhang, Ying

2016-01-01

Genetic variation and phylogenetic relationships among 102 Jatropha curcas accessions from Asia, Africa, and the Americas were assessed using the internal transcribed spacer region of nuclear ribosomal DNA (nrDNA ITS). The average G+C content (65.04%) was considerably higher than the A+T (34.96%) content. The estimated genetic diversity revealed moderate genetic variation. The pairwise genetic divergences (GD) between haplotypes were evaluated and ranged from 0.000 to 0.017, suggesting a higher level of genetic differentiation in Mexican accessions than those of other regions. Phylogenetic relationships and intraspecific divergence were inferred by Bayesian inference (BI), maximum parsimony (MP), and median joining (MJ) network analysis and were generally resolved. The J. curcas accessions were consistently divided into three lineages, groups A, B, and C, which demonstrated distant geographical isolation and genetic divergence between American accessions and those from other regions. The MJ network analysis confirmed that Central America was the possible center of origin. The putative migration route suggested that J. curcas was distributed from Mexico or Brazil, via Cape Verde and then split into two routes. One route was dispersed to Spain, then migrated to China, eventually spreading to southeastern Asia, while the other route was dispersed to Africa, via Madagascar and migrated to China, later spreading to southeastern Asia. Copyright © 2016 Académie des sciences. Published by Elsevier SAS. All rights reserved.

Genetic variation in caribou and reindeer (Rangifer tarandus).

Science.gov (United States)

Cronin, M A; Patton, J C; Balmysheva, N; MacNeil, M D

2003-02-01

Genetic variation at seven microsatellite DNA loci was quantified in 19 herds of wild caribou and domestic reindeer (Rangifer tarandus) from North America, Scandinavia and Russia. There is an average of 2.0-6.6 alleles per locus and observed individual heterozygosity of 0.33-0.50 in most herds. A herd on Svalbard Island, Scandinavia, is an exception, with relatively few alleles and low heterozygosity. The Central Arctic, Western Arctic and Porcupine River caribou herds in Alaska have similar allele frequencies and comprise one breeding population. Domestic reindeer in Alaska originated from transplants from Siberia, Russia, more than 100 years ago. Reindeer in Alaska and Siberia have different allele frequencies at several loci, but a relatively low level of genetic differentiation. Wild caribou and domestic reindeer in Alaska have significantly different allele frequencies at the seven loci, indicating that gene flow between reindeer and caribou in Alaska has been limited.

Genetic calibration of species diversity among North America's freshwater fishes.

Science.gov (United States)

April, Julien; Mayden, Richard L; Hanner, Robert H; Bernatchez, Louis

2011-06-28

Freshwater ecosystems are being heavily exploited and degraded by human activities all over the world, including in North America, where fishes and fisheries are strongly affected. Despite centuries of taxonomic inquiry, problems inherent to species identification continue to hamper the conservation of North American freshwater fishes. Indeed, nearly 10% of species diversity is thought to remain undescribed. To provide an independent calibration of taxonomic uncertainty and to establish a more accessible molecular identification key for its application, we generated a standard reference library of mtDNA sequences (DNA barcodes) derived from expert-identified museum specimens for 752 North American freshwater fish species. This study demonstrates that 90% of known species can be delineated using barcodes. Moreover, it reveals numerous genetic discontinuities indicative of independently evolving lineages within described species, which points to the presence of morphologically cryptic diversity. From the 752 species analyzed, our survey flagged 138 named species that represent as many as 347 candidate species, which suggests a 28% increase in species diversity. In contrast, several species of parasitic and nonparasitic lampreys lack such discontinuity and may represent alternative life history strategies within single species. Therefore, it appears that the current North American freshwater fish taxonomy at the species level significantly conceals diversity in some groups, although artificially creating diversity in others. In addition to providing an easily accessible digital identification system, this study identifies 151 fish species for which taxonomic revision is required.

A revision of the spider genus Selenops Latreille, 1819 (Arachnida, Araneae, Selenopidae) in North America, Central America and the Caribbean.

Science.gov (United States)

Crews, Sarah C

2011-01-01

The spider genus Selenops Latreille, 1819 occurs in both the Old World and New World tropics and subtropics and contains nearly half of the species in the family Selenopidae Simon, 1897. In this paper the members of the genus Selenops found in North America, Central America, and on islands of the Caribbean are revised, excluding Cuban endemics. No taxonomic changes are currently made to the species from the southwestern United States. In total, 21 new species are described, including Selenops arikoksp. n., Selenops chamelasp. n., Selenops amonasp. n., Selenops bawekasp. n., Selenops bocacanadensissp. n., Selenops enriquillosp. n, Selenops ixchelsp. n., Selenops huetocatlsp. n., Selenops kalinagosp. n., Selenops oviedosp. n., Selenops morrosp. n., Selenops deniasp. n., Selenops duansp. n., Selenops malinalxochitlsp. n., Selenops oricuajosp. n., Selenops petenajtoysp. n., Selenops guerrerosp. n., Selenops makimakisp. n., Selenops souligasp. n., Selenops wilmotorumsp. n., and Selenops wilsonisp. n. Six species names were synonymized: Selenops lunatus Muma, 1953 syn. n. =Selenops candidus Muma, 1953; Selenops tehuacanus Muma 1953 syn. n., Selenops galapagoensis Banks, 1902 syn. n. and Selenops vagabundus Kraus, 1955 syn. n. = Selenops mexicanus Keyserling, 1880; Selenops santibanezi Valdez-Mondragón, 2010 syn. n. = Selenops nigromaculatus Keyserling, 1880; and Selenops salvadoranus Chamberlin, 1925 syn. n. = Selenops bifurcatus Banks, 1909. Lectotypes are designated for the following three species: Selenops marginalis F. O. Pickard-Cambridge, 1900 (♂), Selenops morosus Banks, 1898 (♂), and Selenops mexicanus Keyserling, 1880 (♀). The female neotype is designated for Selenops aissus Walckenaer, 1837. The males of Selenops bani Alayón-García, 1992 and Selenops marcanoi Alayón-García, 1992 are described for the first time, and the females of Selenops phaselus Muma, 1953 and Selenops geraldinae Corronca, 1996 are described for the first time. Almost all species

Dissecting the within-Africa ancestry of populations of African descent in the Americas.

Science.gov (United States)

Stefflova, Klara; Dulik, Matthew C; Barnholtz-Sloan, Jill S; Pai, Athma A; Walker, Amy H; Rebbeck, Timothy R

2011-01-06

The ancestry of African-descended Americans is known to be drawn from three distinct populations: African, European, and Native American. While many studies consider this continental admixture, few account for the genetically distinct sources of ancestry within Africa--the continent with the highest genetic variation. Here, we dissect the within-Africa genetic ancestry of various populations of the Americas self-identified as having primarily African ancestry using uniparentally inherited mitochondrial DNA. We first confirmed that our results obtained using uniparentally-derived group admixture estimates are correlated with the average autosomal-derived individual admixture estimates (hence are relevant to genomic ancestry) by assessing continental admixture using both types of markers (mtDNA and Y-chromosome vs. ancestry informative markers). We then focused on the within-Africa maternal ancestry, mining our comprehensive database of published mtDNA variation (∼5800 individuals from 143 African populations) that helped us thoroughly dissect the African mtDNA pool. Using this well-defined African mtDNA variation, we quantified the relative contributions of maternal genetic ancestry from multiple W/WC/SW/SE (West to South East) African populations to the different pools of today's African-descended Americans of North and South America and the Caribbean. Our analysis revealed that both continental admixture and within-Africa admixture may be critical to achieving an adequate understanding of the ancestry of African-descended Americans. While continental ancestry reflects gender-specific admixture processes influenced by different socio-historical practices in the Americas, the within-Africa maternal ancestry reflects the diverse colonial histories of the slave trade. We have confirmed that there is a genetic thread connecting Africa and the Americas, where each colonial system supplied their colonies in the Americas with slaves from African colonies they controlled

Some Recent USF Studies at Volcanoes in Central America

Science.gov (United States)

McNutt, S. R.

2014-12-01

Scientists at the University of South Florida (USF) have been working in Central America for several decades. Efforts have focused on Physical Volcanology in Nicaragua, GPS in Costa Rica, and assessment of Geothermal projects in El Salvador, amongst others. Two years ago a Seismology Lab was established at USF. Personnel now include three Professors, a Post-Doc, and 4 graduate students. Seismic and GPS networks were installed at Telica Volcano, Nicaragua, in 2010 by Roman, LaFemina and colleagues. Data are recorded on site and recovered several times per year at this persistently restless volcano, which has rates of 5 to 1400 low frequency seismic events per day (Rodgers et al., submitted). Proposals have been submitted to install instruments on other Nicaraguan volcanoes, including seismometers, GPS, infrasound, and lightning sensors. This suite of instruments has proven to be very effective to study a range of volcanic processes. The proposals have not been successful to date (some are pending), and alternative funding sources are being explored. One interesting scientific issue is the presence of strong seasonal effects, specifically a pronounced rainy season and dry season and possible interaction between shallow volcanic processes and surface waters. We are also pursuing a variety of studies that are complementary to the instrumental efforts. One such study is examining volcanic earthquake swarms, with the focus to date on identifying diagnostics. One clear pattern is that peak rates often occur early in swarms, whereas the largest M event occurs late. Additional evidence suggests that the seismic source size grows systematically, especially for events with similar waveforms (families). Recognition of such patterns, linked to processes, may help to improve monitoring and better take advantage of instrumental data to reduce vulnerability from eruptions.

Regional Strategic Appraisal of Central America

Science.gov (United States)

2003-04-07

Central America’s multiple transitions (from war to peace, from military rule to civilian, freely and democratically elected, constitutional government...Centroamericanas ‘CFAC’: Un Instrumento de Integracion y Seguridad Regional,” Center for Hemispheric Defense Studies, REDES 2001, Panel for Strategic

Conservation and genetic characterisation of common bean landraces from Cilento region (southern Italy): high differentiation in spite of low genetic diversity.

Science.gov (United States)

De Luca, Daniele; Cennamo, Paola; Del Guacchio, Emanuele; Di Novella, Riccardo; Caputo, Paolo

2018-02-01

Since its introduction from Central-South America to Italy almost 500 years ago, the common bean (Phaseolus vulgaris L.) was largely cultivated across the peninsula in hundreds of different landraces. However, globalisation and technological modernisation of agricultural practices in the last decades promoted the cultivation of few varieties at the expense of traditional and local agro-ecotypes, which have been confined to local markets or have completely disappeared. The aim of this study was to evaluate the genetic diversity and differentiation in 12 common bean landraces once largely cultivated in the Cilento region (Campania region, southern Italy), and now the object of a recovery program to save them from extinction. The analysis conducted using 13 nuclear microsatellite loci in 140 individuals revealed a high degree of homozygosity within each landrace and a strong genetic differentiation that was reflected in the success in assigning individuals to the source landrace. On the contrary, internal transcribed spacers 1 and 2, analysed in one individual per landrace, were highly similar among common bean landraces but allowed the identification of a cowpea variety (Vigna unguiculata Walp.), a crop largely cultivated in the Old World before the arrival of common bean from Americas. In conclusion, our study highlighted that conservation of landraces is important not only for the cultural and socio-economic value that they have for local communities, but also because the time and conditions in which they have been selected have led to that genetic distinctiveness that is at the basis of many potential agronomical applications and dietary benefits.

Genetic Affiliation of Pre-Hispanic and Contemporary Mayas Through Maternal Linage.

Science.gov (United States)

Ochoa-Lugo, Mirna Isabel; Muñoz, María de Lourdes; Pérez-Ramírez, Gerardo; Beaty, Kristine G; López-Armenta, Mauro; Cervini-Silva, Javiera; Moreno-Galeana, Miguel; Meza, Adrián Martínez; Ramos, Eduardo; Crawford, Michael H; Romano-Pacheco, Arturo

2016-04-01

Maya civilization developed in Mesoamerica and encompassed the Yucatan Peninsula, Guatemala, Belize, part of the Mexican states of Tabasco and Chiapas, and the western parts of Honduras and El Salvador. This civilization persisted approximately 3,000 years and was one of the most advanced of its time, possessing the only known full writing system at the time, as well as art, sophisticated architecture, and mathematical and astronomical systems. This civilization reached the apex of its power and influence during the Preclassic period, from 2000 BCE to 250 CE. Genetic variation in the pre-Hispanic Mayas from archaeological sites in the Mexican states of Yucatan, Chiapas, Quintana Roo, and Tabasco and their relationship with the contemporary communities in these regions have not been previously studied. Consequently, the principal aim of this study was to determine mitochondrial DNA (mtDNA) variation in the pre-Hispanic Maya population and to assess the relationship of these individuals with contemporary Mesoamerican Maya and populations from Asia, Beringia, and North, Central, and South America. Our results revealed interactions and gene flow between populations in the different archaeological sites assessed in this study. The mtDNA haplogroup frequency in the pre-Hispanic Maya population (60.53%, 34.21%, and 5.26% for haplogroups A, C, and D, respectively) was similar to that of most Mexican and Guatemalan Maya populations, with haplogroup A exhibiting the highest frequency. Haplogroup B most likely arrived independently and mixed with populations carrying haplogroups A and C based on its absence in the pre-Hispanic Mexican Maya populations and low frequencies in most Mexican and Guatemalan Maya populations, although this also may be due to drift. Maya and Ciboneys sharing haplotype H10 belonged to haplogroup C1 and haplotype H4 of haplogroup D, suggesting shared regional haplotypes. This may indicate a shared genetic ancestry, suggesting more regional interaction

Geomorphological impact on agroforestry systems in the interior highlands of Nicaragua, Central America

Science.gov (United States)

Mentler, Axel; Wriessnig, Karin; Ottner, Franz; Schomakers, Jasmin; Benavides González, Álvaro; Cisne Contreras, José Dolores; Querol Lipcovich, Daniel

2013-04-01

Cerro el Castillo is located in the NW of Nicaragua, Central America, close to the border of Honduras (Provincia Central de las Cordilleras) at 1000-1200m above sea level. In this region, small and medium-sized farms are agroforestry systems with mangos, avocados, coffee, papayas, bananas, strawberries, maize, pumpkins, beans and other vegetables. The production systems are strongly linked to facilities for raising small domestic animals and cows. Main regional agricultural production problems are steep slopes, soil erosion, varying precipitation and distribution, water management and the unstable family income. An investigation of topsoil properties with comparable management systems showed on small scales significant differences in key values of soil chemistry and mineralogy. The outline of the analytical parameters included determination of pH, electrical conductivity (EC), cation exchange capacity (CEC), organic carbon (TOC), dissolved organic carbon (DOC), total nitrogen (TN) and dissolved nitrogen (DN) in soil solution, and plant available nutrients (P and K). The soil's mineralogical composition was determined by X-ray diffraction analysis. The area is a highly weathered karst landscape within a tropical limestone region displaying different amounts of volcanic pyroclastic parent material. The dominant Nitisoils and Andosols show degraded argic and andic horizons along the upper half of the mountainside. The pH values in the topsoil are moderate from pH 5.0 to 5.6. The upland topsoil is decalcified and the amount of plant available phosphorous is very low with significant low Ca concentration at the sorption complex. The mineralogical composition points to the high weathering intensity of this area (high content of kaolinite and a lower concentration of potassium and plagioclase feldspars and andesite). Along the upper half of the mountain, the soil profiles show wider C:N ratios and lower amounts of organic matter. Topsoil at lower altitude and with a lower

Postglacial recolonization in a cold climate specialist in western Europe: patterns of genetic diversity in the adder (Vipera berus) support the central-marginal hypothesis.

Science.gov (United States)

Ursenbacher, Sylvain; Guillon, Michaël; Cubizolle, Hervé; Dupoué, Andréaz; Blouin-Demers, Gabriel; Lourdais, Olivier

2015-07-01

Understanding the impact of postglacial recolonization on genetic diversity is essential in explaining current patterns of genetic variation. The central-marginal hypothesis (CMH) predicts a reduction in genetic diversity from the core of the distribution to peripheral populations, as well as reduced connectivity between peripheral populations. While the CMH has received considerable empirical support, its broad applicability is still debated and alternative hypotheses predict different spatial patterns of genetic diversity. Using microsatellite markers, we analysed the genetic diversity of the adder (Vipera berus) in western Europe to reconstruct postglacial recolonization. Approximate Bayesian Computation (ABC) analyses suggested a postglacial recolonization from two routes: a western route from the Atlantic Coast up to Belgium and a central route from the Massif Central to the Alps. This cold-adapted species likely used two isolated glacial refugia in southern France, in permafrost-free areas during the last glacial maximum. Adder populations further from putative glacial refugia had lower genetic diversity and reduced connectivity; therefore, our results support the predictions of the CMH. Our study also illustrates the utility of highly variable nuclear markers, such as microsatellites, and ABC to test competing recolonization hypotheses. © 2015 John Wiley & Sons Ltd.

Drug resistance associated genetic polymorphisms in Plasmodium falciparum and Plasmodium vivax collected in Honduras, Central America.

Science.gov (United States)

Jovel, Irina T; Mejía, Rosa E; Banegas, Engels; Piedade, Rita; Alger, Jackeline; Fontecha, Gustavo; Ferreira, Pedro E; Veiga, Maria I; Enamorado, Irma G; Bjorkman, Anders; Ursing, Johan

2011-12-19

In Honduras, chloroquine and primaquine are recommended and still appear to be effective for treatment of Plasmodium falciparum and Plasmodium vivax malaria. The aim of this study was to determine the proportion of resistance associated genetic polymorphisms in P. falciparum and P. vivax collected in Honduras. Blood samples were collected from patients seeking medical attention at the Hospital Escuela in Tegucigalpa from 2004 to 2006 as well as three regional hospitals, two health centres and one regional laboratory during 2009. Single nucleotide polymorphisms in P. falciparum chloroquine resistance transporter (pfcrt), multidrug resistance 1 (pfmdr1), dihydrofolate reductase (pfdhfr) and dihydropteroate synthase (pfdhps) genes and in P. vivax multidrug resistance 1 (pvmdr1) and dihydrofolate reductase (pvdhfr) genes were detected using PCR based methods. Thirty seven P. falciparum and 64 P. vivax samples were collected. All P. falciparum infections acquired in Honduras carried pfcrt, pfmdr1, pfdhps and pfdhfr alleles associated with chloroquine, amodiaquine and sulphadoxine-pyrimethamine sensitivity only. One patient with parasites acquired on a Pacific Island had pfcrt 76 T and pfmdr1 86Y alleles. That patient and a patient infected in West Africa had pfdhfr 51I, 59 R and 108 N alleles. Pvmdr1 976 F was found in 7/37 and two copies of pvmdr1 were found in 1/37 samples. Pvdhfr 57 L + 58 R was observed in 2/57 samples. The results indicate that P. falciparum from Honduras remain sensitive to chloroquine and sulphadoxine-pyrimethamine. This suggests that chloroquine and sulphadoxine-pyrimethamine should be efficacious for treatment of uncomplicated P. falciparum malaria, supporting current national treatment guidelines. However, genetic polymorphisms associated with chloroquine and sulphadoxine-pyrimethamine tolerance were detected in local P. vivax and imported P. falciparum infections. Continuous monitoring of the prevalence of drug resistant/tolerant P

Latin America Report.

Science.gov (United States)

1986-11-17

yesterday, the reserved market throughout the country for in- formatics has also been extended to computer software programs. The DIARIO OFICIAL ...Pemex Northern States Price Cuts 97 PARAGUAY Journalists Union Denounces Arrest of Members (EL DIARIO , 25 Oct 86) .....; .. 98 Police...topple the elected government in Man- • agua — including US$200 000 to the anti-San- dinista "Friends of the Democratic Centre in Central America". I

Consultants Group Meeting on Genetic Sexing and Population Genetics of Screwworms. Working Material

International Nuclear Information System (INIS)

2000-01-01

A Thematic Plan on SIT for Screwworms developed in 1999 by IPC and TC identified certain R and D bottlenecks to the expansion of this technology into new agricultural areas. This consultant's meeting was held to review these conclusions and to advise the Agency on the need, or otherwise, of initiating a CRP to address the bottlenecks identified in the Thematic Plan. In 2001 it is expected that the New World Screwworm, Cochliomyia hominivorax, will have been eradicated from all of Central America, including Panama where a sterile release barrier will be established to prevent re-invasion from South America. This barrier will need to be maintained indefinitely with its associated costs. The use of an all-male strain in the production facility would have very positive impact on the cost/benefit analysis of the programme. The Director of the Screwworm Programme in Central America made this point very strongly during the Thematic Plan discussions and at a subsequent technical meeting in Tuxtla Gutierrez. Interest to expand the programme into South America is now being shown by certain countries in the region where the economic feasibility of implementing an SIT programme might depend on producing sterile flies more economically and here again the use of a genetic sexing strain could play an important role. For the Old World Screwworm, Chrysomya bezziana the Australian authorities have just completed a successful small field trial of the SIT in Malaysia and it is proposed that more extensive field tests be carried out in the region. For both the New World Screwworm in South America and the Old World Screwworm, in Asia there is virtually no information regarding the population structure in relation to the implementation of an SIT programme. Is the Old World Screwworm a single species over its very wide distribution and are the populations of New World Screwworm in South America the same as in Central America and related to each other? Are the populations isolated? These

Molecular genetic variation in sheep of the central Volga area inhabited by Finno-Ugric peoples

Directory of Open Access Journals (Sweden)

M. TAPIO

2008-12-01

Full Text Available Based on morphology, native northern European sheep breeds belong to the short tailed type, of which the Romanov is the only native example still distributed in northwest Russia. Besides this, there exist local sheep populations kept by Finno-Ugric peoples in the central Volga region, which represent additional genetic resources in the area. Four sheep populations from the central Volga region were genotyped for 20 microsatellites and compared with geographically proximate breeds (Estonian Whitehead and Blackhead, the Finnsheep and an exported and a native population of Russian Romanov and with local populations in Estonia, Finland and Russian Karelia. Between-breed analyses including admixture analysis using molecular genetic markers and the phenotypic characteristics indicated that the Volgaic populations have not remained pure. The Viena population from Russian Karelia, the Romanov breed and, to some extent, the Komi population, have escaped extensive mixing, making them most attractive for conservation programmes. The study compared imported and native Romanov breed populations and the results suggest that the diversity parameters are markedly similar in these two populations.;

Genetic parameters for type classification of Nelore cattle on central performance tests at pasture in Brazil.

Science.gov (United States)

Lima, Paulo Ricardo Martins; Paiva, Samuel Rezende; Cobuci, Jaime Araujo; Braccini Neto, José; Machado, Carlos Henrique Cavallari; McManus, Concepta

2013-10-01

The objective of this study was to characterize Nelore cattle on central performance tests in pasture, ranked by the visual classification method EPMURAS (structure, precocity, muscle, navel, breed, posture, and sexual characteristics), and to estimate genetic and phenotypic correlations between these parameters, including visual as well as production traits (initial and final weight on test, weight gain, and weight corrected for 550 days). The information used in the study was obtained on 21,032 Nelore bulls which were participants in the central performance test at pasture of the Brazilian Association for Zebu Breeders (ABCZ). Heritabilities obtained were from 0.19 to 0.50. Phenotypic correlations were positive from 0.70 to 0.97 between the weight traits, from 0.65 to 0.74 between visual characteristics, and from 0.29 to 0.47 between visual characteristics and weight traits. The genetic correlations were positive ranging from 0.80 to 0.98 between the characteristics of structure, precocity and musculature, from 0.13 to 0.64 between the growth characteristics, and from 0.41 to 0.97 between visual scores and weight gains. Heritability and genetic correlations indicate that the use of visual scores, along with the selection for growth characteristics, can bring positive results in selection of beef cattle for rearing on pasture.

Peterjamesia circumscripta (Leight.) D. Hawksw. (Roccellaceae: Ascomycota): First record to continental South America

OpenAIRE

Gumboski, Emerson; Eliasaro, Sionara

2012-01-01

Peterjamesia circumscripta, previously known from Australia, Europe, North Africa, North and Central America, and Galapagos Islands was collected in southern Brazil. This is the first record of this species in continental South America.

Genetic characterization of dengue virus type 3 isolates in the State of Rio de Janeiro, 2001

OpenAIRE

Miagostovich, M.P.; Santos, F.B. dos; Simone, T.S. de; Costa, E.V.; Filippis, A.M.B.; Schatzmayr, H.G.; Nogueira, R.M.R.

2002-01-01

The genetic characterization of dengue virus type 3 (DEN-3) strains isolated from autochthonous cases in the State of Rio de Janeiro, Brazil, in 2001 is presented. Restriction site-specific (RSS)-PCR performed on 22 strains classified the Brazilian DEN-3 viruses as subtype C, a subtype that contains viruses from Sri Lanka, India, Africa and recent isolates from Central America. Nucleic acid sequencing (positions 278 to 2550) of one DEN-3 strain confirmed the origin of these strains, since gen...

The Central American Network for Disaster and Health Information.

Science.gov (United States)

Arnesen, Stacey J; Cid, Victor H; Scott, John C; Perez, Ricardo; Zervaas, Dave

2007-07-01

This paper describes an international outreach program to support rebuilding Central America's health information infrastructure after several natural disasters in the region, including Hurricane Mitch in 1998 and two major earthquakes in 2001. The National Library of Medicine joined forces with the Pan American Health Organization/World Health Organization, the United Nations International Strategy for Disaster Reduction, and the Regional Center of Disaster Information for Latin America and the Caribbean (CRID) to strengthen libraries and information centers in Central America and improve the availability of and access to health and disaster information in the region by developing the Central American Network for Disaster and Health Information (CANDHI). Through CRID, the program created ten disaster health information centers in medical libraries and disaster-related organizations in six countries. This project served as a catalyst for the modernization of several medical libraries in Central America. The resulting CANDHI provides much needed electronic access to public health "gray literature" on disasters, as well as access to numerous health information resources. CANDHI members assist their institutions and countries in a variety of disaster preparedness activities through collecting and disseminating information.

Spatiotemporal dynamics of DENV-2 Asian-American genotype lineages in the Americas.

Directory of Open Access Journals (Sweden)

Daiana Mir

Full Text Available The Asian/American (AS/AM genotype of dengue virus type 2 (DENV-2 has been evolving in the Americas over the last 30 years, leading to several waves of dengue epidemics and to the emergence of different viral lineages in the region. In this study, we investigate the spatiotemporal dissemination pattern of the DENV-2 lineages at a regional level. We applied phylogenetic and phylogeographic analytical methods to a comprehensive data set of 582 DENV-2 E gene sequences of the AS/AM genotype isolated from 29 different American countries over a period of 30 years (1983 to 2012. Our study reveals that genetic diversity of DENV-2 AS/AM genotype circulating in the Americas mainly resulted from one single founder event and can be organized in at least four major lineages (I to IV, which emerged in the Caribbean region at the early 1980s and then spread and die out with different dynamics. Lineages I and II dominate the epidemics in the Caribbean region during the 1980s and early 1990 s, lineage III becomes the prevalent DENV-2 one in the Caribbean and South America during the 1990 s, whereas lineage IV dominates the epidemics in South and Central America during the 2000s. Suriname and Guyana seem to represent important entry points for DENV-2 from the Lesser Antilles to South America, whereas Venezuela, Brazil and Nicaragua were pointed as the main secondary hubs of dissemination to other mainland countries. Our study also indicates that DENV-2 AS/AM genotype was disseminated within South America following two main routes. The first route hits Venezuela and the western side of the Andes, while the second route mainly hits Brazil and the eastern side of the Andes. The phenomenon of DENV-2 lineage replacement across successive epidemic outbreaks was a common characteristic in all American countries, although the timing of lineage replacements greatly vary across locations.

Satellite-based detection of volcanic sulphur dioxide from recent eruptions in Central and South America

Directory of Open Access Journals (Sweden)

D. Loyola

2008-01-01

Full Text Available Volcanic eruptions can emit large amounts of rock fragments and fine particles (ash into the atmosphere, as well as several gases, including sulphur dioxide (SO₂. These ejecta and emissions are a major natural hazard, not only to the local population, but also to the infrastructure in the vicinity of volcanoes and to aviation. Here, we describe a methodology to retrieve quantitative information about volcanic SO₂ plumes from satellite-borne measurements in the UV/Visible spectral range. The combination of a satellite-based SO₂ detection scheme and a state-of-the-art 3D trajectory model enables us to confirm the volcanic origin of trace gas signals and to estimate the plume height and the effective emission height. This is demonstrated by case-studies for four selected volcanic eruptions in South and Central America, using the GOME, SCIAMACHY and GOME-2 instruments.

Range-Wide Genetic Analysis of Little Brown Bat (Myotis lucifugus Populations: Estimating the Risk of Spread of White-Nose Syndrome.

Directory of Open Access Journals (Sweden)

Maarten J Vonhof

Full Text Available The little brown bat (Myotis lucifugus is one of the most widespread bat species in North America and is experiencing severe population declines because of an emerging fungal disease, white-nose syndrome (WNS. To manage and conserve this species effectively it is important to understand patterns of gene flow and population connectivity to identify possible barriers to disease transmission. However, little is known about the population genetic structure of little brown bats, and to date, no studies have investigated population structure across their entire range. We examined mitochondrial DNA and nuclear microsatellites in 637 little brown bats (including all currently recognized subspecific lineages from 29 locations across North America, to assess levels of genetic variation and population differentiation across the range of the species, including areas affected by WNS and those currently unaffected. We identified considerable spatial variation in patterns of female dispersal and significant genetic variation between populations in eastern versus western portions of the range. Overall levels of nuclear genetic differentiation were low, and there is no evidence for any major barriers to gene flow across their range. However, patterns of mtDNA differentiation are highly variable, with high ΦST values between most sample pairs (including between all western samples, between western and eastern samples, and between some eastern samples, while low mitochondrial differentiation was observed within two groups of samples found in central and eastern regions of North America. Furthermore, the Alaskan population was highly differentiated from all others, and western populations were characterized by isolation by distance while eastern populations were not. These data raise the possibility that the current patterns of spread of WNS observed in eastern North America may not apply to the entire range and that there may be broad-scale spatial variation in

Two new genera of metalmark butterflies of North and Central America (Lepidoptera, Riodinidae

Directory of Open Access Journals (Sweden)

Marysol Trujano-Ortega

2018-01-01

Full Text Available Two new genera of Riodinidae (Insecta: Lepidoptera are described, Neoapodemia Trujano-Ortega, gen. n. (Neoapodemia nais (W. H. Edwards, 1876, comb. n., N. chisosensis Freeman, 1964, comb. n. and Plesioarida Trujano-Ortega & García-Vázquez, gen. n. (Plesioarida palmerii palmerii (W. H. Edwards, 1870, comb. n., P. palmerii arizona (Austin, [1989], comb. n., P. palmerii australis (Austin, [1989], comb. n., P. hepburni hepburni (Godman & Salvin, 1886, comb. n., P. hepburni remota (Austin, 1991, comb. n., P. murphyi (Austin, [1989], comb. n., P. hypoglauca hypoglauca (Godman & Salvin, 1878, comb. n., P. hypoglauca wellingi (Ferris, 1985, comb. n., P. walkeri (Godman & Salvin, 1886, comb. n., P. selvatica (De la Maza & De la Maza, 2017, comb. n.. Neoapodemia Trujano-Ortega, gen. n. is distributed in the southwestern USA and northeastern Mexico, while Plesioarida Trujano-Ortega & García-Vázquez, gen. n. is present from the southern USA to Central America. Species of these genera were previously classified as Apodemia C. Felder & R. Felder but molecular and morphological evidence separate them as new taxa. Morphological diagnoses and descriptions are provided for both new genera, including the main distinctive characters from labial palpi, prothoracic legs, wing venation and genitalia, as well as life history traits. A molecular phylogeny of one mitochondrial gene (COI and two nuclear genes (EF-1a and wg are also presented of most species of Apodemia, Neoapodemia Trujano-Ortega, gen. n., Plesioarida Trujano-Ortega & García-Vázquez, gen. n., and sequences of specimens from all tribes of Riodinidae. We compare the characters of Apodemia, Neoapodemia Trujano-Ortega, gen. n. and Plesioarida Trujano-Ortega & García-Vázquez, gen. n. and discuss the differences that support the description of these new taxa. This is a contribution to the taxonomy of the Riodinidae of North America of which the generic diversity is greater than previously recognized.

Why is Liberal Peace-building so Difficult? Some Lessons from Central America

Directory of Open Access Journals (Sweden)

Sabine Kurtenbach

2010-04-01

Full Text Available According to the liberal peace-building paradigm the termination of war is a window of opportunity for fundamental change. Central America has been one of the first laboratories of international policies promoting the threefold transformation process of pacification, democratization and economic liberalization. Although none of the postwar countries (Nicaragua, El Salvador, Guatemala slipped back into war, serious deficits abound that can neither be explained as mere consequences of war nor as ‘normal’ developmental problems. The paper introduces an analytical framework locating these problems at the intersection between external influences, societal foundations, consequences of war and violence as well as peace-building. The comparative analysis of the three transformation processes – democratization, market economy and pacification – shows how path dependent patterns remain dominant while reform processes are fragile. This allows for an explanation of common features as well as differences inside the region. Resumen: ¿Por qué es tan difícil la construcción de una paz liberal? Algunas lecciones de América CentralDe acuerdo al paradigma liberal sobre la construcción de la paz, el fin de una guerra abre un abanico de oportunidades para introducir cambios fundamentales. América Central fue uno de los primeros laboratorios donde se aplicaron políticas internacionales que fomentaban el triple proceso de transformación compuesto por la pacificación, la democratización y la liberalización económica. Aunque ninguna de las sociedades de posguerra (Nicaragua, El Salvador, Guatemala volvió a recaer en ella, abundan graves deficiencias que no se pueden explicar ni como meras consecuencias del conflicto ni como problemas ‘normales’ de países en desarrollo. El artículo define un marco analítico que localiza estos problemas en la intersección de influencias externas, bases sociales, consecuencias de la guerra y violencia as

The status of cryptococcosis in Latin America

Directory of Open Access Journals (Sweden)

Carolina Firacative

2018-04-01

Full Text Available Cryptococcosis is a life-threatening fungal infection caused by the encapsulated yeasts Cryptococcus neoformans and C. gattii, acquired from the environment. In Latin America, as occurring worldwide, C. neoformans causes more than 90% of the cases of cryptococcosis, affecting predominantly patients with HIV, while C. gattii generally affects otherwise healthy individuals. In this region, cryptococcal meningitis is the most common presentation, with amphotericin B and fluconazole being the antifungal drugs of choice. Avian droppings are the predominant environmental reservoir of C. neoformans, while C. gattii is associated with several arboreal species. Importantly, C. gattii has a high prevalence in Latin America and has been proposed to be the likely origin of some C. gattii populations in North America. Thus, in the recent years, significant progress has been made with the study of the basic biology and laboratory identification of cryptococcal strains, in understanding their ecology, population genetics, host-pathogen interactions, and the clinical epidemiology of this important mycosis in Latin America.

The Role of Long-Term Tectonic Deformation on the Distribution of Present-Day Seismic Activity in the Caribbean and Central America

Science.gov (United States)

Schobelock, J.; Stamps, D. S.; Pagani, M.; Garcia, J.; Styron, R. H.

2017-12-01

The Caribbean and Central America region (CCAR) undergoes the entire spectrum of earthquake types due to its complex tectonic setting comprised of transform zones, young oceanic spreading ridges, and subductions along its eastern and western boundaries. CCAR is, therefore, an ideal setting in which to study the impacts of long-term tectonic deformation on the distribution of present-day seismic activity. In this work, we develop a continuous tectonic strain rate model based on inter-seismic geodetic data and compare it with known active faults and earthquake focal mechanism data. We first create a 0.25o x 0.25o finite element mesh that is comprised of block geometries defined in previously studies. Second, we isolate and remove transient signals from the latest open access community velocity solution from UNAVCO, which includes 339 velocities from COCONet and TLALOCNet GNSS data for the Caribbean and Central America, respectively. In a third step we define zones of deformation and rigidity by creating a buffer around the boundary of each block that varies depending on the size of the block and the expected deformation zone based on locations of GNSS data that are consistent with rigid block motion. We then assign each node within the buffer a 0 for the deforming areas and a plate index outside the buffer for the rigid. Finally, we calculate a tectonic strain rate model for CCAR using the Haines and Holt finite element approach to fit bi-cubic Bessel splines to the the GNSS/GPS data assuming block rotation for zones of rigidity. Our model of the CCAR is consistent with compression along subduction zones, extension across the mid-Pacific Rise, and a combination of compression and extension across the North America - Caribbean plate boundary. The majority of CCAR strain rate magnitudes range from -60 to 60 nanostrains/yr. Modeling results are then used to calculate expected faulting behaviors that we compare with mapped geologic faults and seismic activity.

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Journals; Journal of Genetics. Joseph M. Shostell. Articles written in Journal of Genetics. Volume 84 Issue 2 August 2005 pp 147-171 Research Article. Population genetic analysis of cat populations from Mexico, Colombia, Bolivia, and the Dominican Republic: identification of different gene pools in Latin America.

Dissecting the genetic architecture of frost tolerance in Central European winter wheat.

Science.gov (United States)

Zhao, Yusheng; Gowda, Manje; Würschum, Tobias; Longin, C Friedrich H; Korzun, Viktor; Kollers, Sonja; Schachschneider, Ralf; Zeng, Jian; Fernando, Rohan; Dubcovsky, Jorge; Reif, Jochen C

2013-11-01

Abiotic stress tolerance in plants is pivotal to increase yield stability, but its genetic basis is still poorly understood. To gain insight into the genetic architecture of frost tolerance, this work evaluated a large mapping population of 1739 wheat (Triticum aestivum L.) lines and hybrids adapted to Central Europe in field trials in Germany and fingerprinted the lines with a 9000 single-nucleotide polymorphism array. Additive effects prevailed over dominance effects. A two-dimensional genome scan revealed the presence of epistatic effects. Genome-wide association mapping in combination with a robust cross-validation strategy identified one frost tolerance locus with a major effect located on chromosome 5B. This locus was not in linkage disequilibrium with the known frost loci Fr-B1 and Fr-B2. The use of the detected diagnostic markers on chromosome 5B, however, does not allow prediction of frost tolerance with high accuracy. Application of genome-wide selection approaches that take into account also loci with small effect sizes considerably improved prediction of the genetic variation of frost tolerance in wheat. The developed prediction model is valuable for improving frost tolerance because this trait displays a wide variation in occurrence across years and is therefore a difficult target for conventional phenotypic selection.

Native South American genetic structure and prehistory inferred from hierarchical modeling of mtDNA.

Science.gov (United States)

Lewis, Cecil M; Long, Jeffrey C

2008-03-01

Genetic diversity in Native South Americans forms a complex pattern at both the continental and local levels. In comparing the West to the East, there is more variation within groups and smaller genetic distances between groups. From this pattern, researchers have proposed that there is more variation in the West and that a larger, more genetically diverse, founding population entered the West than the East. Here, we question this characterization of South American genetic variation and its interpretation. Our concern arises because others have inferred regional variation from the mean variation within local populations without taking into account the variation among local populations within the same region. This failure produces a biased view of the actual variation in the East. In this study, we analyze the mitochondrial DNA sequence between positions 16040 and 16322 of the Cambridge reference sequence. Our sample represents a total of 886 people from 27 indigenous populations from South (22), Central (3), and North America (2). The basic unit of our analyses is nucleotide identity by descent, which is easily modeled and proportional to nucleotide diversity. We use a forward modeling strategy to fit a series of nested models to identity by descent within and between all pairs of local populations. This method provides estimates of identity by descent at different levels of population hierarchy without assuming homogeneity within populations, regions, or continents. Our main discovery is that Eastern South America harbors more genetic variation than has been recognized. We find no evidence that there is increased identity by descent in the East relative to the total for South America. By contrast, we discovered that populations in the Western region, as a group, harbor more identity by descent than has been previously recognized, despite the fact that average identity by descent within groups is lower. In this light, there is no need to postulate separate founding

Heart Failure in North America

OpenAIRE

Blair, John E. A; Huffman, Mark; Shah, Sanjiv J

2013-01-01

Heart failure is a major health problem that affects patients and healthcare systems worldwide. Within the continent of North America, differences in economic development, genetic susceptibility, cultural practices, and trends in risk factors and treatment all contribute to both inter-continental and within-continent differences in heart failure. The United States and Canada represent industrialized countries with similar culture, geography, and advanced economies and infrastructure. During t...

Ground Motion Characteristics of Induced Earthquakes in Central North America

Science.gov (United States)

Atkinson, G. M.; Assatourians, K.; Novakovic, M.

2017-12-01

The ground motion characteristics of induced earthquakes in central North America are investigated based on empirical analysis of a compiled database of 4,000,000 digital ground-motion records from events in induced-seismicity regions (especially Oklahoma). Ground-motion amplitudes are characterized non-parametrically by computing median amplitudes and their variability in magnitude-distance bins. We also use inversion techniques to solve for regional source, attenuation and site response effects. Ground motion models are used to interpret the observations and compare the source and attenuation attributes of induced earthquakes to those of their natural counterparts. Significant conclusions are that the stress parameter that controls the strength of high-frequency radiation is similar for induced earthquakes (depth of h 5 km) and shallow (h 5 km) natural earthquakes. By contrast, deeper natural earthquakes (h 10 km) have stronger high-frequency ground motions. At distances close to the epicenter, a greater focal depth (which increases distance from the hypocenter) counterbalances the effects of a larger stress parameter, resulting in motions of similar strength close to the epicenter, regardless of event depth. The felt effects of induced versus natural earthquakes are also investigated using USGS "Did You Feel It?" reports; 400,000 reports from natural events and 100,000 reports from induced events are considered. The felt reports confirm the trends that we expect based on ground-motion modeling, considering the offsetting effects of the stress parameter versus focal depth in controlling the strength of motions near the epicenter. Specifically, felt intensity for a given magnitude is similar near the epicenter, on average, for all event types and depths. At distances more than 10 km from the epicenter, deeper events are felt more strongly than shallow events. These ground-motion attributes imply that the induced-seismicity hazard is most critical for facilities in

Dirofilariosis in the Americas: a more virulent Dirofilaria immitis?

Science.gov (United States)

Dantas-Torres, Filipe; Otranto, Domenico

2013-10-02

Dirofilarioses are widespread diseases caused by filarioid nematodes (superfamily Filarioidea) of the genus Dirofilaria, which are transmitted by a plethora of mosquito species. The principal agent of canine dirofilariosis in the Americas is Dirofilaria immitis, which may also occasionally infest humans, resulting in pulmonary nodules that may be confounded with malignant lung tumours. Because human cases of dirofilariosis by D. immitis are relatively frequent in the Americas and rare in Europe and other eastern countries, where Dirofilaria repens is the main causative agent, the existence of a more virulent strain of D. immitis in the Americas has been speculated. Recently, a case of human ocular infestation by Dirofilaria sp. was diagnosed in Pará State, northern Brazil, where canine heartworm dirofilariosis is endemic. The nematode was shown to be morphologically and phylogenetically related to D. immitis but it was genetically distinct from reference sequences, including those of D. immitis infesting dogs in the same geographical area. This finding raised questions regarding the aetiology of human dirofilariosis in the Americas, since information on the genetic makeup of filarioids infesting dogs and humans is meagre. Further studies would be needed to better characterize filarioids infesting dogs, wild animals, and humans in the Americas and to assess the existence of a more virulent D. immitis strain in this continent. Finally, the competence of different culicid species/strains from Europe and the Americas as vectors of Dirofilaria species should be investigated. Such studies would help us to understand possible variations in transmission patterns and even to predict possible scenarios that may emerge in the future, with the introduction of non-endemic Dirofilaria species/strains in free areas through importation of infested animals, vectors, or both.

Clustering of 770,000 genomes reveals post-colonial population structure of North America

Science.gov (United States)

Han, Eunjung; Carbonetto, Peter; Curtis, Ross E.; Wang, Yong; Granka, Julie M.; Byrnes, Jake; Noto, Keith; Kermany, Amir R.; Myres, Natalie M.; Barber, Mathew J.; Rand, Kristin A.; Song, Shiya; Roman, Theodore; Battat, Erin; Elyashiv, Eyal; Guturu, Harendra; Hong, Eurie L.; Chahine, Kenneth G.; Ball, Catherine A.

2017-02-01

Despite strides in characterizing human history from genetic polymorphism data, progress in identifying genetic signatures of recent demography has been limited. Here we identify very recent fine-scale population structure in North America from a network of over 500 million genetic (identity-by-descent, IBD) connections among 770,000 genotyped individuals of US origin. We detect densely connected clusters within the network and annotate these clusters using a database of over 20 million genealogical records. Recent population patterns captured by IBD clustering include immigrants such as Scandinavians and French Canadians; groups with continental admixture such as Puerto Ricans; settlers such as the Amish and Appalachians who experienced geographic or cultural isolation; and broad historical trends, including reduced north-south gene flow. Our results yield a detailed historical portrait of North America after European settlement and support substantial genetic heterogeneity in the United States beyond that uncovered by previous studies.

Genetic diversity, endemism and phylogeny of lampreys within the genus Lampetra sensu stricto (Petromyzontiformes: Petromyzontidae) in western North America.

Science.gov (United States)

Boguski, D A; Reid, S B; Goodman, D H; Docker, M F

2012-11-01

Phylogenetic structure of four Lampetra species from the Pacific drainage of North America (western brook lamprey Lampetra richardsoni, Pacific brook lamprey Lampetra pacifica, river lamprey Lampetra ayresii and Kern brook lamprey Lampetra hubbsi) and unidentified Lampetra specimens (referred to as Lampetra sp.) from 36 locations was estimated using the mitochondrial cytochrome b gene. Maximum parsimony and Bayesian inferences did not correspond with any taxonomic scheme proposed to date. Rather, although L. richardsoni (from Alaska to California) and L. ayresii (from British Columbia to California) together constituted a well-supported clade distinct from several genetically divergent Lampetra populations in Oregon and California, these two species were not reciprocally monophyletic. The genetically divergent populations included L. pacifica (from the Columbia River basin) and L. hubbsi (from the Kern River basin) and four Lampetra sp. populations in Oregon (Siuslaw River and Fourmile Creek) and California (Kelsey and Mark West Creeks). These four Lampetra sp. populations showed genetic divergence between 2.3 and 5.7% from any known species (and up to 8.0% from each other), and may represent morphologically cryptic and thus previously undescribed species. A fifth population (from Paynes Creek, California) may represent a range extension of L. hubbsi into the Upper Sacramento River. © 2012 The Authors. Journal of Fish Biology © 2012 The Fisheries Society of the British Isles.

Genetic diversity and host specificity varies across three genera of blood parasites in ducks of the Pacific Americas Flyway

Science.gov (United States)

Reeves, Andrew B.; Smith, Matthew M.; Meixell, Brandt W.; Fleskes, Joseph P.; Ramey, Andrew M.

2015-01-01

Birds of the order Anseriformes, commonly referred to as waterfowl, are frequently infected by Haemosporidia of the genera Haemoproteus, Plasmodium, and Leucocytozoon via dipteran vectors. We analyzed nucleotide sequences of the Cytochrome b (Cytb) gene from parasites of these genera detected in six species of ducks from Alaska and California, USA to characterize the genetic diversity of Haemosporidia infecting waterfowl at two ends of the Pacific Americas Flyway. In addition, parasite Cytb sequences were compared to those available on a public database to investigate specificity of genetic lineages to hosts of the order Anseriformes. Haplotype and nucleotide diversity of Haemoproteus Cytb sequences was lower than was detected for Plasmodium and Leucocytozoon parasites. Although waterfowl are presumed to be infected by only a single species of Leucocytozoon, L. simondi, diversity indices were highest for haplotypes from this genus and sequences formed five distinct clades separated by genetic distances of 4.9%–7.6%, suggesting potential cryptic speciation. All Haemoproteus andLeucocytozoon haplotypes derived from waterfowl samples formed monophyletic clades in phylogenetic analyses and were unique to the order Anseriformes with few exceptions. In contrast, waterfowl-origin Plasmodium haplotypes were identical or closely related to lineages found in other avian orders. Our results suggest a more generalist strategy for Plasmodiumparasites infecting North American waterfowl as compared to those of the generaHaemoproteus and Leucocytozoon.

Trends in Longevity in the Americas: Disparities in Life Expectancy in Women and Men, 1965-2010.

Directory of Open Access Journals (Sweden)

Ian R Hambleton

Full Text Available We describe trends in life expectancy at birth (LE and between-country LE disparities since 1965, in Latin America and the Caribbean.LE trends since 1965 are described for three geographical sub-regions: the Caribbean, Central America, and South America. LE disparities are explored using a suite of absolute and relative disparity metrics, with measurement consensus providing confidence to observed differences. LE has increased throughout Latin America and the Caribbean. Compared to the Caribbean, LE has increased by an additional 6.6 years in Central America and 4.1 years in South America. Since 1965, average reductions in between-country LE disparities were 14% (absolute disparity and 23% (relative disparity in the Caribbean, 55% and 51% in Central America, 55% and 52% in South America.LE in Latin America and the Caribbean is exceeding 'minimum standard' international targets, and is improving relative to the world region with the highest human longevity. The Caribbean, which had the highest LE and the lowest between-country LE disparities in Latin America and the Caribbean in 1965-70, had the lowest LE and the highest LE disparities by 2005-10. Caribbean Governments have championed a collaborative solution to the growing burden of non-communicable disease, with 15 territories signing on to the Declaration of Port of Spain, signalling regional commitment to a coordinated public-health response. The persistent LE inequity between Caribbean countries suggests that public health interventions should be tailored to individual countries to be most effective. Between- and within-country disparity monitoring for a range of health metrics should be a priority, first to guide country-level policy initiatives, then to contribute to the assessment of policy success.

Experts discuss unconventional conflicts in the Americas | IDRC ...

International Development Research Centre (IDRC) Digital Library (Canada)

2015-07-10

Jul 10, 2015 ... Experts discuss unconventional conflicts in the Americas ... in illicit activities — like drug smuggling and illegal mining — that destabilize societies and ruin lives. ... Social exclusion and "violences" in Central American cities.

Variability and population genetic structure in Achyrocline flaccida (Weinm. DC., a species with high value in folk medicine in South America.

Directory of Open Access Journals (Sweden)

Juliana da Rosa

Full Text Available Better knowledge of medicinal plant species and their conservation is an urgent need worldwide. Decision making for conservation strategies can be based on the knowledge of the variability and population genetic structure of the species and on the events that may influence these genetic parameters. Achyrocline flaccida (Weinm. DC. is a native plant from the grassy fields of South America with high value in folk medicine. In spite of its importance, no genetic and conservation studies are available for the species. In this work, microsatellite and ISSR (inter-simple sequence repeat markers were used to estimate the genetic variability and structure of seven populations of A. flaccida from southern Brazil. The microsatellite markers were inefficient in A. flaccida owing to a high number of null alleles. After the evaluation of 42 ISSR primers on one population, 10 were selected for further analysis of seven A. flaccida populations. The results of ISSR showed that the high number of exclusive absence of loci might contribute to the inter-population differentiation. Genetic variability of the species was high (Nei's diversity of 0.23 and Shannon diversity of 0.37. AMOVA indicated higher genetic variability within (64.7% than among (33.96% populations, and the variability was unevenly distributed (FST 0.33. Gene flow among populations ranged from 1.68 to 5.2 migrants per generation, with an average of 1.39. The results of PCoA and Bayesian analyses corroborated and indicated that the populations are structured. The observed genetic variability and population structure of A. flaccida are discussed in the context of the vegetation formation history in southern Brazil, as well as the possible anthropogenic effects. Additionally, we discuss the implications of the results in the conservation of the species.

Genetic characterization of dengue virus type 3 isolates in the State of Rio de Janeiro, 2001

Directory of Open Access Journals (Sweden)

M.P. Miagostovich

2002-08-01

Full Text Available The genetic characterization of dengue virus type 3 (DEN-3 strains isolated from autochthonous cases in the State of Rio de Janeiro, Brazil, in 2001 is presented. Restriction site-specific (RSS-PCR performed on 22 strains classified the Brazilian DEN-3 viruses as subtype C, a subtype that contains viruses from Sri Lanka, India, Africa and recent isolates from Central America. Nucleic acid sequencing (positions 278 to 2550 of one DEN-3 strain confirmed the origin of these strains, since genotype III - classified by sequencing - and RSS-PCR subtype C are correlated. This genetic subtype has been associated with hemorrhagic dengue epidemics and the information provided here could be useful to implement appropriate prevention and control measures.

Ancient DNA Analysis Suggests Negligible Impact of the Wari Empire Expansion in Peru's Central Coast during the Middle Horizon.

Science.gov (United States)

Valverde, Guido; Barreto Romero, María Inés; Flores Espinoza, Isabel; Cooper, Alan; Fehren-Schmitz, Lars; Llamas, Bastien; Haak, Wolfgang

2016-01-01

The analysis of ancient human DNA from South America allows the exploration of pre-Columbian population history through time and to directly test hypotheses about cultural and demographic evolution. The Middle Horizon (650-1100 AD) represents a major transitional period in the Central Andes, which is associated with the development and expansion of ancient Andean empires such as Wari and Tiwanaku. These empires facilitated a series of interregional interactions and socio-political changes, which likely played an important role in shaping the region's demographic and cultural profiles. We analyzed individuals from three successive pre-Columbian cultures present at the Huaca Pucllana archaeological site in Lima, Peru: Lima (Early Intermediate Period, 500-700 AD), Wari (Middle Horizon, 800-1000 AD) and Ychsma (Late Intermediate Period, 1000-1450 AD). We sequenced 34 complete mitochondrial genomes to investigate the potential genetic impact of the Wari Empire in the Central Coast of Peru. The results indicate that genetic diversity shifted only slightly through time, ruling out a complete population discontinuity or replacement driven by the Wari imperialist hegemony, at least in the region around present-day Lima. However, we caution that the very subtle genetic contribution of Wari imperialism at the particular Huaca Pucllana archaeological site might not be representative for the entire Wari territory in the Peruvian Central Coast.

Ancient DNA Analysis Suggests Negligible Impact of the Wari Empire Expansion in Peru's Central Coast during the Middle Horizon.

Directory of Open Access Journals (Sweden)

Guido Valverde

Full Text Available The analysis of ancient human DNA from South America allows the exploration of pre-Columbian population history through time and to directly test hypotheses about cultural and demographic evolution. The Middle Horizon (650-1100 AD represents a major transitional period in the Central Andes, which is associated with the development and expansion of ancient Andean empires such as Wari and Tiwanaku. These empires facilitated a series of interregional interactions and socio-political changes, which likely played an important role in shaping the region's demographic and cultural profiles. We analyzed individuals from three successive pre-Columbian cultures present at the Huaca Pucllana archaeological site in Lima, Peru: Lima (Early Intermediate Period, 500-700 AD, Wari (Middle Horizon, 800-1000 AD and Ychsma (Late Intermediate Period, 1000-1450 AD. We sequenced 34 complete mitochondrial genomes to investigate the potential genetic impact of the Wari Empire in the Central Coast of Peru. The results indicate that genetic diversity shifted only slightly through time, ruling out a complete population discontinuity or replacement driven by the Wari imperialist hegemony, at least in the region around present-day Lima. However, we caution that the very subtle genetic contribution of Wari imperialism at the particular Huaca Pucllana archaeological site might not be representative for the entire Wari territory in the Peruvian Central Coast.

Love in the Time of War. Affections and Disaffections in the Testimonial Literature of Central America

Directory of Open Access Journals (Sweden)

José Domingo Carrillo Padilla

2013-07-01

Full Text Available The article aims to know the relationships established between the militants of the armed movements. Also want to be aware of the relationship model that prevailed. To achieve the proposed objectives, leave aside the narratives that glorify the armed movements, prevents build heroes to taste, rather, is a narrative of the adventures and the loving sinventuras who sought by weapons, to relieve the power ruler in Central America in the second half of the 20th century. The relationships established between the militants of the armed movements, regulated by traditional institutions such as marriage and free joints. In this article, because the nature of the sources this was said, emphasis in heterosexual affective relationships. There is know in the same way, homosexual relations between the guerrillas. Taboo because it means to infringe against the virility of men in arms and the model of femininity established by society. Son amores that even they dare not speak its name.

Reviewing the history of HIV-1: spread of subtype B in the Americas.

Directory of Open Access Journals (Sweden)

Dennis Maletich Junqueira

Full Text Available The dispersal of HIV-1 subtype B (HIV-1B is a reflection of the movement of human populations in response to social, political, and geographical issues. The initial dissemination of HIV-1B outside Africa seems to have included the passive involvement of human populations from the Caribbean in spreading the virus to the United States. However, the exact pathways taken during the establishment of the pandemic in the Americas remain unclear. Here, we propose a geographical scenario for the dissemination of HIV-1B in the Americas, based on phylogenetic and genetic statistical analyses of 313 available sequences of the pol gene from 27 countries. Maximum likelihood and bayesian inference methods were used to explore the phylogenetic relationships between HIV-1B sequences, and molecular variance estimates were analyzed to infer the genetic structure of the viral population. We found that the initial dissemination and subsequent spread of subtype B in the Americas occurred via a single introduction event in the Caribbean around 1964 (1950-1967. Phylogenetic trees present evidence of several primary outbreaks in countries in South America, directly seeded by the Caribbean epidemic. Cuba is an exception insofar as its epidemic seems to have been introduced from South America. One clade comprising isolates from different countries emerged in the most-derived branches, reflecting the intense circulation of the virus throughout the American continents. Statistical analysis supports the genetic compartmentalization of the virus among the Americas, with a close relationship between the South American and Caribbean epidemics. These findings reflect the complex establishment of the HIV-1B pandemic and contribute to our understanding between the migration process of human populations and virus diffusion.

High genetic diversity among and within bitter manioc varieties cultivated in different soil types in Central Amazonia

Directory of Open Access Journals (Sweden)

Alessandro Alves-Pereira

2017-04-01

Full Text Available Abstract Although manioc is well adapted to nutrient-poor Oxisols of Amazonia, ethnobotanical observations show that bitter manioc is also frequently cultivated in the highly fertile soils of the floodplains and Amazonian dark earths (ADE along the middle Madeira River. Because different sets of varieties are grown in each soil type, and there are agronomic similarities between ADE and floodplain varieties, it was hypothesized that varieties grown in ADE and floodplain were more closely related to each other than either is to varieties grown in Oxisols. We tested this hypothesis evaluating the intra-varietal genetic diversity and the genetic relationships among manioc varieties commonly cultivated in Oxisols, ADE and floodplain soils. Genetic results did not agree with ethnobotanical expectation, since the relationships between varieties were variable and most individuals of varieties with the same vernacular name, but grown in ADE and floodplain, were distinct. Although the same vernacular name could not always be associated with genetic similarities, there is still a great amount of variation among the varieties. Many ecological and genetic processes may explain the high genetic diversity and differentiation found for bitter manioc varieties, but all contribute to the maintenance and amplification of genetic diversity within the manioc in Central Amazonia.

Novel Strain of Andes Virus Associated with Fatal Human Infection, Central Bolivia

Science.gov (United States)

Cruz, Cristhopher D.; Vallejo, Efrain; Agudo, Roberto; Vargas, Jorge; Blazes, David L.; Guevara, Carolina; Laguna-Torres, V. Alberto; Halsey, Eric S.; Kochel, Tadeusz J.

2012-01-01

To better describe the genetic diversity of hantaviruses associated with human illness in South America, we screened blood samples from febrile patients in Chapare Province in central Bolivia during 2008–2009 for recent hantavirus infection. Hantavirus RNA was detected in 3 patients, including 1 who died. Partial RNA sequences of small and medium segments from the 3 patients were most closely related to Andes virus lineages but distinct (1 hantaviruses; the highest prevalence was among agricultural workers. Because of the high level of human exposure to hantavirus strains and the severity of resulting disease, additional studies are warranted to determine the reservoirs, ecologic range, and public health effect of this novel strain of hantavirus. PMID:22515983

Successes, challenges and needs regarding rural health medical education in continental Central America: a literature review and narrative synthesis.

Science.gov (United States)

Colon-Gonzalez, Maria C; El Rayess, Fadya; Guevara, Sara; Anandarajah, Gowri

2015-01-01

Central American countries, like many others, face a shortage of rural health physicians. Most medical schools in this region are located in urban areas and focus on tertiary care training rather than on community health or primary care, which are better suited for rural practice. However, many countries require young physicians to do community service in rural communities to address healthcare provider shortages. This study aimed to: (a) synthesize what is known about the current state of medical education preparing physicians for rural practice in this region, and (b) identify common needs, challenges and opportunities for improving medical education in this area. A comprehensive literature review was conducted between December 2013 and May 2014. The stepwise, reproducible search process included English and Spanish language resources from both data-based web search engines (PubMed, Web of Science/Web of Knowledge, ERIC and Google Scholar) and the grey literature. Search criteria included MeSH terms: 'medical education', 'rural health', 'primary care', 'community medicine', 'social service', in conjunction with 'Central America', 'Latin America', 'Mexico', 'Guatemala', 'Belize', 'El Salvador', 'Nicaragua', 'Honduras', 'Costa Rica' and 'Panama'. Articles were included in the review if they (1) were published after 1984; (2) focused on medical education for rural health, primary care, community health; and (3) involved the countries of interest. A narrative synthesis of the content of resources meeting inclusion criteria was done using qualitative research methods to identify common themes pertaining to the study goals. The search revealed 20 resources that met inclusion criteria. Only four of the 20 were research articles; therefore, information about this subject was primarily derived from expert opinion. Thematic analysis revealed the historical existence of several innovative programs that directly address rural medicine training needs, suggesting that

Genetic diversity of Plasmodium vivax and Plasmodium falciparum in Honduras.

Science.gov (United States)

Lopez, Ana Cecilia; Ortiz, Andres; Coello, Jorge; Sosa-Ochoa, Wilfredo; Torres, Rosa E Mejia; Banegas, Engels I; Jovel, Irina; Fontecha, Gustavo A

2012-11-26

Understanding the population structure of Plasmodium species through genetic diversity studies can assist in the design of more effective malaria control strategies, particularly in vaccine development. Central America is an area where malaria is a public health problem, but little is known about the genetic diversity of the parasite's circulating species. This study aimed to investigate the allelic frequency and molecular diversity of five surface antigens in field isolates from Honduras. Five molecular markers were analysed to determine the genotypes of Plasmodium vivax and Plasmodium falciparum from endemic areas in Honduras. Genetic diversity of ama-1, msp-1 and csp was investigated for P. vivax, and msp-1 and msp-2 for P. falciparum. Allelic frequencies were calculated and sequence analysis performed. A high genetic diversity was observed within Plasmodium isolates from Honduras. A different number of genotypes were elucidated: 41 (n = 77) for pvama-1; 23 (n = 84) for pvcsp; and 23 (n = 35) for pfmsp-1. Pvcsp sequences showed VK210 as the only subtype present in Honduran isolates. Pvmsp-1 (F2) was the most polymorphic marker for P. vivax isolates while pvama-1 was least variable. All three allelic families described for pfmsp-1 (n = 30) block 2 (K1, MAD20, and RO33), and both allelic families described for the central domain of pfmsp-2 (n = 11) (3D7 and FC27) were detected. However, K1 and 3D7 allelic families were predominant. All markers were randomly distributed across the country and no geographic correlation was found. To date, this is the most complete report on molecular characterization of P. vivax and P. falciparum field isolates in Honduras with regards to genetic diversity. These results indicate that P. vivax and P. falciparum parasite populations are highly diverse in Honduras despite the low level of transmission.

NIDDK Central Repository

Data.gov (United States)

U.S. Department of Health & Human Services — The NIDDK Central Repository stores biosamples, genetic and other data collected in designated NIDDK-funded clinical studies. The purpose of the NIDDK Central...

Ancient DNA Analysis Suggests Negligible Impact of the Wari Empire Expansion in Peru’s Central Coast during the Middle Horizon

Science.gov (United States)

Barreto Romero, María Inés; Flores Espinoza, Isabel; Cooper, Alan; Fehren-Schmitz, Lars

2016-01-01

The analysis of ancient human DNA from South America allows the exploration of pre-Columbian population history through time and to directly test hypotheses about cultural and demographic evolution. The Middle Horizon (650–1100 AD) represents a major transitional period in the Central Andes, which is associated with the development and expansion of ancient Andean empires such as Wari and Tiwanaku. These empires facilitated a series of interregional interactions and socio-political changes, which likely played an important role in shaping the region’s demographic and cultural profiles. We analyzed individuals from three successive pre-Columbian cultures present at the Huaca Pucllana archaeological site in Lima, Peru: Lima (Early Intermediate Period, 500–700 AD), Wari (Middle Horizon, 800–1000 AD) and Ychsma (Late Intermediate Period, 1000–1450 AD). We sequenced 34 complete mitochondrial genomes to investigate the potential genetic impact of the Wari Empire in the Central Coast of Peru. The results indicate that genetic diversity shifted only slightly through time, ruling out a complete population discontinuity or replacement driven by the Wari imperialist hegemony, at least in the region around present-day Lima. However, we caution that the very subtle genetic contribution of Wari imperialism at the particular Huaca Pucllana archaeological site might not be representative for the entire Wari territory in the Peruvian Central Coast. PMID:27248693

Evidence of two genetic clusters of manatees with low genetic diversity in Mexico and implications for their conservation

Science.gov (United States)

Nourisson, C.; Morales-Vela, B.; Padilla-Saldivar, J.; Tucker, K.P.; Clark, A.; Olivera-Gomez, L. D.; Bonde, R.; McGuire, P.

2011-01-01

The Antillean manatee (Trichechus manatus manatus) occupies the tropical coastal waters of the Greater Antilles and Caribbean, extending from Mexico along Central and South America to Brazil. Historically, manatees were abundant in Mexico, but hunting during the pre-Columbian period, the Spanish colonization and throughout the history of Mexico, has resulted in the significantly reduced population occupying Mexico today. The genetic structure, using microsatellites, shows the presence of two populations in Mexico: the Gulf of Mexico (GMx) and Chetumal Bay (ChB) on the Caribbean coast, with a zone of admixture in between. Both populations show low genetic diversity (GMx: NA=2.69; HE=0.41 and ChB: NA=3.0; HE=0.46). The lower genetic diversity found in the GMx, the largest manatee population in Mexico, is probably due to a combination of a founder effect, as this is the northern range of the sub-species of T. m. manatus, and a bottleneck event. The greater genetic diversity observed along the Caribbean coast, which also has the smallest estimated number of individuals, is possibly due to manatees that come from the GMx and Belize. There is evidence to support limited or unidirectional gene flow between these two important areas. The analyses presented here also suggest minimal evidence of a handful of individual migrants possibly between Florida and Mexico. To address management issues we suggest considering two distinct genetic populations in Mexico, one along the Caribbean coast and one in the riverine systems connected to the GMx. ?? 2011 Springer Science+Business Media B.V.

Evidence of two genetic clusters of manatees with low genetic diversity in Mexico and implications for their conservation.

Science.gov (United States)

Nourisson, Coralie; Morales-Vela, Benjamín; Padilla-Saldívar, Janneth; Tucker, Kimberly Pause; Clark, Annmarie; Olivera-Gómez, Leon David; Bonde, Robert; McGuire, Peter

2011-07-01

The Antillean manatee (Trichechus manatus manatus) occupies the tropical coastal waters of the Greater Antilles and Caribbean, extending from Mexico along Central and South America to Brazil. Historically, manatees were abundant in Mexico, but hunting during the pre-Columbian period, the Spanish colonization and throughout the history of Mexico, has resulted in the significantly reduced population occupying Mexico today. The genetic structure, using microsatellites, shows the presence of two populations in Mexico: the Gulf of Mexico (GMx) and Chetumal Bay (ChB) on the Caribbean coast, with a zone of admixture in between. Both populations show low genetic diversity (GMx: N(A) = 2.69; H(E) = 0.41 and ChB: N(A) = 3.0; H(E) = 0.46). The lower genetic diversity found in the GMx, the largest manatee population in Mexico, is probably due to a combination of a founder effect, as this is the northern range of the sub-species of T. m. manatus, and a bottleneck event. The greater genetic diversity observed along the Caribbean coast, which also has the smallest estimated number of individuals, is possibly due to manatees that come from the GMx and Belize. There is evidence to support limited or unidirectional gene flow between these two important areas. The analyses presented here also suggest minimal evidence of a handful of individual migrants possibly between Florida and Mexico. To address management issues we suggest considering two distinct genetic populations in Mexico, one along the Caribbean coast and one in the riverine systems connected to the GMx.

Evidence of two genetic clusters of manatees with low genetic diversity in Mexico and implications for their conservation

Science.gov (United States)

Nourisson, Coralie; Morales-Vela, Benjamin; Padilla-Saldivar, Janneth; Tucker, Kimberly Pause; Clark, Ann Marie; Olivera-Gomez, Leon David; Bonde, Robert; McGuire, Peter

2011-01-01

The Antillean manatee (Trichechus manatus manatus) occupies the tropical coastal waters of the Greater Antilles and Caribbean, extending from Mexico along Central and South America to Brazil. Historically, manatees were abundant in Mexico, but hunting during the pre-Columbian period, the Spanish colonization and throughout the history of Mexico, has resulted in the significantly reduced population occupying Mexico today. The genetic structure, using microsatellites, shows the presence of two populations in Mexico: the Gulf of Mexico (GMx) and Chetumal Bay (ChB) on the Caribbean coast, with a zone of admixture in between. Both populations show low genetic diversity (GMx: NA = 2.69; HE = 0.41 and ChB: NA = 3.0; HE = 0.46). The lower genetic diversity found in the GMx, the largest manatee population in Mexico, is probably due to a combination of a founder effect, as this is the northern range of the sub-species of T. m. manatus, and a bottleneck event. The greater genetic diversity observed along the Caribbean coast, which also has the smallest estimated number of individuals, is possibly due to manatees that come from the GMx and Belize. There is evidence to support limited or unidirectional gene flow between these two important areas. The analyses presented here also suggest minimal evidence of a handful of individual migrants possibly between Florida and Mexico. To address management issues we suggest considering two distinct genetic populations in Mexico, one along the Caribbean coast and one in the riverine systems connected to the GMx.

Central American Climatology

Science.gov (United States)

1985-04-01

Central America, as where mean temperatures are relatively warm throughout the year de- so spite seasonal rainfall changes. 75 Elevation, solar angle...November 1982 Control Hidalgo Anos.1952-1963, Republica de Nicaragua, Ministerio de Formento Y O0.PP, Comision Nacional de Energia . Craig, Richard A., The

The human gut microbiome of Latin America populations: a landscape to be discovered.

Science.gov (United States)

Magne, Fabien; O'Ryan, Miguel L; Vidal, Roberto; Farfan, Mauricio

2016-10-01

The gut microbiome is critical for human health, and its alteration is associated with intestinal, autoimmune and metabolic diseases. Numerous studies have focused on prevention or treatment of dysbiotic microbiome to reduce the risk or effect of these diseases. A key issue is to define the microbiome associated with the state of good health. The purpose of this review is to describe factors influencing the gut microbiome with special emphasis on contributions from Latin America. In addition, we will highlight opportunities for future studies on gut microbiome in Latin America. A relevant factor influencing gut microbiome composition is geographical location associated with specific genetic, dietary and lifestyle factors. Geographical specificities suggest that a universal 'healthy microbiome' is unlikely. Several research programs, mostly from Europe and North America, are extensively sequencing gut microbiome of healthy people, whereas data from Latin America remain scarce yet slowly increasing. Few studies have shown difference in the composition of gut microbiome between their local populations with that of other industrialized countries (North American populations). Latin America is composed of countries with a myriad of lifestyles, traditions, genetic backgrounds and socioeconomic conditions, which may determine differences in gut microbiome of individuals from different countries. This represents an opportunity to better understand the relationship between these factors and gut microbiome.

Origin of silicic magmas along the Central American volcanic front: Genetic relationship to mafic melts

Science.gov (United States)

Vogel, Thomas A.; Patino, Lina C.; Eaton, Jonathon K.; Valley, John W.; Rose, William I.; Alvarado, Guillermo E.; Viray, Ela L.

2006-09-01

Silicic pyroclastic flows and related deposits are abundant along the Central American volcanic front. These silicic magmas erupted through both the non-continental Chorotega block to the southeast and the Paleozoic continental Chortis block to the northwest. The along-arc variations of the silicic deposits with respect to diagnostic trace element ratios (Ba/La, U/Th, Ce/Pb), oxygen isotopes, Nd and Sr isotope ratios mimic the along-arc variation in the basaltic and andesitic lavas. This variation in the lavas has been interpreted to indicate relative contributions from the slab and asthenosphere to the basaltic magmas [Carr, M.J., Feigenson, M.D., Bennett, E.A., 1990. Incompatible element and isotopic evidence for tectonic control of source mixing and melt extraction along the Central American arc. Contributions to Mineralogy and Petrology, 105, 369-380.; Patino, L.C., Carr, M.J. and Feigenson, M.D., 2000. Local and regional variations in Central American arc lavas controlled by variations in subducted sediment input. Contributions to Mineralogy and Petrology, 138 (3), 265-283.]. With respect to along-arc trends in basaltic lavas the largest contribution of slab fluids is in Nicaragua and the smallest input from the slab is in central Costa Rica — similar trends are observed in the silicic pyroclastic deposits. Data from melting experiments of primitive basalts and basaltic andesites demonstrate that it is difficult to produce high K 2O/Na 2O silicic magmas by fractional crystallization or partial melting of low-K 2O/Na 2O sources. However fractional crystallization or partial melting of medium- to high-K basalts can produce these silicic magmas. We interpret that the high-silica magmas associated Central America volcanic front are partial melts of penecontemporaneous, mantle-derived, evolved magmas that have ponded and crystallized in the mid-crust — or are melts extracted from these nearly completely crystallized magmas.

Genomic Insights into the Ancestry and Demographic History of South America

Science.gov (United States)

Homburger, Julian R.; Moreno-Estrada, Andrés; Gignoux, Christopher R.; Nelson, Dominic; Sanchez, Elena; Ortiz-Tello, Patricia; Pons-Estel, Bernardo A.; Acevedo-Vasquez, Eduardo; Miranda, Pedro; Langefeld, Carl D.; Gravel, Simon; Alarcón-Riquelme, Marta E.; Bustamante, Carlos D.

2015-01-01

South America has a complex demographic history shaped by multiple migration and admixture events in pre- and post-colonial times. Settled over 14,000 years ago by Native Americans, South America has experienced migrations of European and African individuals, similar to other regions in the Americas. However, the timing and magnitude of these events resulted in markedly different patterns of admixture throughout Latin America. We use genome-wide SNP data for 437 admixed individuals from 5 countries (Colombia, Ecuador, Peru, Chile, and Argentina) to explore the population structure and demographic history of South American Latinos. We combined these data with population reference panels from Africa, Asia, Europe and the Americas to perform global ancestry analysis and infer the subcontinental origin of the European and Native American ancestry components of the admixed individuals. By applying ancestry-specific PCA analyses we find that most of the European ancestry in South American Latinos is from the Iberian Peninsula; however, many individuals trace their ancestry back to Italy, especially within Argentina. We find a strong gradient in the Native American ancestry component of South American Latinos associated with country of origin and the geography of local indigenous populations. For example, Native American genomic segments in Peruvians show greater affinities with Andean indigenous peoples like Quechua and Aymara, whereas Native American haplotypes from Colombians tend to cluster with Amazonian and coastal tribes from northern South America. Using ancestry tract length analysis we modeled post-colonial South American migration history as the youngest in Latin America during European colonization (9–14 generations ago), with an additional strong pulse of European migration occurring between 3 and 9 generations ago. These genetic footprints can impact our understanding of population-level differences in biomedical traits and, thus, inform future medical

Genomic Insights into the Ancestry and Demographic History of South America.

Directory of Open Access Journals (Sweden)

Julian R Homburger

2015-12-01

Full Text Available South America has a complex demographic history shaped by multiple migration and admixture events in pre- and post-colonial times. Settled over 14,000 years ago by Native Americans, South America has experienced migrations of European and African individuals, similar to other regions in the Americas. However, the timing and magnitude of these events resulted in markedly different patterns of admixture throughout Latin America. We use genome-wide SNP data for 437 admixed individuals from 5 countries (Colombia, Ecuador, Peru, Chile, and Argentina to explore the population structure and demographic history of South American Latinos. We combined these data with population reference panels from Africa, Asia, Europe and the Americas to perform global ancestry analysis and infer the subcontinental origin of the European and Native American ancestry components of the admixed individuals. By applying ancestry-specific PCA analyses we find that most of the European ancestry in South American Latinos is from the Iberian Peninsula; however, many individuals trace their ancestry back to Italy, especially within Argentina. We find a strong gradient in the Native American ancestry component of South American Latinos associated with country of origin and the geography of local indigenous populations. For example, Native American genomic segments in Peruvians show greater affinities with Andean indigenous peoples like Quechua and Aymara, whereas Native American haplotypes from Colombians tend to cluster with Amazonian and coastal tribes from northern South America. Using ancestry tract length analysis we modeled post-colonial South American migration history as the youngest in Latin America during European colonization (9-14 generations ago, with an additional strong pulse of European migration occurring between 3 and 9 generations ago. These genetic footprints can impact our understanding of population-level differences in biomedical traits and, thus, inform

Genomic Insights into the Ancestry and Demographic History of South America.

Science.gov (United States)

Homburger, Julian R; Moreno-Estrada, Andrés; Gignoux, Christopher R; Nelson, Dominic; Sanchez, Elena; Ortiz-Tello, Patricia; Pons-Estel, Bernardo A; Acevedo-Vasquez, Eduardo; Miranda, Pedro; Langefeld, Carl D; Gravel, Simon; Alarcón-Riquelme, Marta E; Bustamante, Carlos D

2015-12-01

South America has a complex demographic history shaped by multiple migration and admixture events in pre- and post-colonial times. Settled over 14,000 years ago by Native Americans, South America has experienced migrations of European and African individuals, similar to other regions in the Americas. However, the timing and magnitude of these events resulted in markedly different patterns of admixture throughout Latin America. We use genome-wide SNP data for 437 admixed individuals from 5 countries (Colombia, Ecuador, Peru, Chile, and Argentina) to explore the population structure and demographic history of South American Latinos. We combined these data with population reference panels from Africa, Asia, Europe and the Americas to perform global ancestry analysis and infer the subcontinental origin of the European and Native American ancestry components of the admixed individuals. By applying ancestry-specific PCA analyses we find that most of the European ancestry in South American Latinos is from the Iberian Peninsula; however, many individuals trace their ancestry back to Italy, especially within Argentina. We find a strong gradient in the Native American ancestry component of South American Latinos associated with country of origin and the geography of local indigenous populations. For example, Native American genomic segments in Peruvians show greater affinities with Andean indigenous peoples like Quechua and Aymara, whereas Native American haplotypes from Colombians tend to cluster with Amazonian and coastal tribes from northern South America. Using ancestry tract length analysis we modeled post-colonial South American migration history as the youngest in Latin America during European colonization (9-14 generations ago), with an additional strong pulse of European migration occurring between 3 and 9 generations ago. These genetic footprints can impact our understanding of population-level differences in biomedical traits and, thus, inform future medical

Oil supply in Central and South America

International Nuclear Information System (INIS)

Aguilera, Roberto F.

2009-01-01

This paper estimates a cumulative supply curve for conventional oil in the Central and South American (CSA) region. The curve includes volumes from provinces not previously assessed by other organizations, as well as reserve growth. Volumes for the previously unassessed provinces are estimated using a variable shape distribution (VSD) model. Then the volumes are allocated to CSA countries based on each country's share of proved reserves. Figures provided by the cumulative supply curve are stock variables for all time, unlike the traditional supply curve where they are flow variables that can continue from one period to the next. In this study, the fixed stock approach is used since it provides practical information with respect to the concerns that some have expressed about oil scarcity in the near future. Results indicate that Central and South American oil is more abundant than often assumed, and can be produced at costs below current market oil prices, and substantially below mid-2008 prices.

Intra-Arc extension in Central America: Links between plate motions, tectonics, volcanism, and geochemistry

Science.gov (United States)

Phipps Morgan, Jason; Ranero, Cesar; Vannucchi, Paola

2010-05-01

This study revisits the kinematics and tectonics of Central America subduction, synthesizing observations of marine bathymetry, high-resolution land topography, current plate motions, and the recent seismotectonic and magmatic history in this region. The inferred tectonic history implies that the Guatemala-El Salvador and Nicaraguan segments of this volcanic arc have been a region of significant arc tectonic extension; extension arising from the interplay between subduction roll-back of the Cocos Plate and the ~10-15 mm/yr slower westward drift of the Caribbean plate relative to the North American Plate. The ages of belts of magmatic rocks paralleling both sides of the current Nicaraguan arc are consistent with long-term arc-normal extension in Nicaragua at the rate of ~5-10 mm/yr, in agreement with rates predicted by plate kinematics. Significant arc-normal extension can ‘hide' a very large intrusive arc-magma flux; we suggest that Nicaragua is, in fact, the most magmatically robust section of the Central American arc, and that the volume of intrusive volcanism here has been previously greatly underestimated. Yet, this flux is hidden by the persistent extension and sediment infill of the rifting basin in which the current arc sits. Observed geochemical differences between the Nicaraguan arc and its neighbors which suggest that Nicaragua has a higher rate of arc-magmatism are consistent with this interpretation. Smaller-amplitude, but similar systematic geochemical correlations between arc-chemistry and arc-extension in Guatemala show the same pattern as the even larger variations between the Nicaragua arc and its neighbors. We are also exploring the potential implications of intra-arc extension for deformation processes along the subducting plate boundary and within the forearc ‘microplate'.

Analysis of genetic relationships of mulberry (Morus L.) germplasm ...

African Journals Online (AJOL)

STORAGESEVER

2009-06-03

Jun 3, 2009 ... Full Length Research Paper. Analysis of genetic ... Key words: Mulberry, molecular marker, genetic diversity, SRAP. ... Europe, North and South America, and Africa, and it is cultivated ... Xingjiang autonomous region, China.

Sub-Saharan centralized biorepository for genetic and genomic research.

Science.gov (United States)

Gasmelseed, Nagla; Elsir, Afrah Awad; Deblasio, Pasquale; Biunno, Ida

2012-04-15

Quality-assessed biomedical samples are essential for academia- and industry driven research on human diseases. The etiologies and the molecular genetic factors relevant in African diseases, including both infections and complex degenerative diseases as well as cancer, need to be studied using well annotated and well-preserved biosamples acquired from native African ethnic groups and compare the results with non-African populations and/or with Afro-Americans. However, a number of difficulties negatively impact on the possibility to obtain clinically annotated biological samples in most Sub-Saharan African countries. This is mainly due to major organizational problems, lack of clinical centres that can dedicate resources to research, as well as lack of facilities in which biomaterials can be properly processed and safely stored. Harmonization of biosample acquisition, storage phenotyping schemes and biocomputer infrastructures are the principal objectives of biological resource centers (BRCs). BRCs comprise biobanks of different formats (collection of blood, DNA, tissues, etc., annotated with medical, environmental, life-style and follow up data) a fundamental tool for molecular epidemiological studies aiming to increase excellence and efficacy of biomedical results, drug development and public health. BRCs provide large and highly controlled biomolecular resources necessary to meet the "omics" scientific platforms. Sudan may be a candidate nation to host such infrastructure, in view of its strategic geographical position and the already existing simple biobanking experiences connected with research groups in Central Sudan. Here, we describe the potential role of biobanks in African genetic studies aiming to dissect the eziopathogenesis of complex diseases in relation to environmental and life-style factors. Copyright © 2010 Elsevier B.V. All rights reserved.

First record of the genus Ctenipocoris (Heteroptera: Naucoridae) in Central America, with a preliminary key to the American species and description of a new species.

Science.gov (United States)

Herrera, Federico

2013-10-31

A new naucorid species, Ctenipocoris oscari Herrera NEW SPECIES, is herein described for Costa Rica. It is the first species to be described in Central America and the sixth American species. Comparative notes are provided to differentiate this species from the others. Type material is deposited at the Zoological Museum of the University of Costa Rica (MZUCR), San José, Costa Rica. A preliminary key to the American species of the genus is provided.

Genetic variation in Miscanthus x giganteus and the importance of estimating genetic distance tresholds for differentiating clones

DEFF Research Database (Denmark)

Glowacka, K; Clark, L; Adhikari, S

2015-01-01

Miscanthus × giganteus (Mxg) is an important bioenergy feedstock crop, however, genetic diversity among legacy cultivars may be severely constrained. Only one introduction from Japan to Denmark of this sterile, triploid, vegetatively propagated crop was recorded in the 1930s. We sought to determi...... new triploid Mxg progeny ranged from 0.46 to 0.56. Though genetic diversity among the Mxg legacy cultivars is critically low, new crosses can provide much-needed variation to growers......Miscanthus × giganteus (Mxg) is an important bioenergy feedstock crop, however, genetic diversity among legacy cultivars may be severely constrained. Only one introduction from Japan to Denmark of this sterile, triploid, vegetatively propagated crop was recorded in the 1930s. We sought to determine...... if the Mxg cultivars in North America were all synonyms, and if they were derived from the European introduction. We used 64 nuclear and five chloroplast simple sequence repeat (SSR) markers to estimate genetic similarity for 27 Mxg accessions from North America, and compared them with six accessions from...

Molecular Detection and Identification of Rickettsia Species in Ticks (Acari: Ixodidae) Collected From Belize, Central America.

Science.gov (United States)

Polsomboon, Suppaluck; Hoel, David F; Murphy, Jittawadee R; Linton, Yvonne-Marie; Motoki, Maysa; Robbins, Richard G; Bautista, Kim; Bricen O, Ireneo; Achee, Nicole L; Grieco, John P; Ching, Wei-Mei; Chao, Chien-Chung

2017-11-07

Little is known about tick-borne rickettsial pathogens in Belize, Central America. We tested ixodid ticks for the presence of Rickettsia species in three of the six northern and western Belizean districts. Ticks were collected from domestic animals and tick drags over vegetation in 23 different villages in November 2014, February 2015, and May 2015. A total of 2,506 collected ticks were identified to the following species: Dermacentor nitens Neumann (46.69%), Rhipicephalus sanguineus (Latreille) (19.55%), Rhipicephalus microplus (Canestrini) (19.47%), Amblyomma cajennense complex (9.74%), Amblyomma maculatum Koch (3.47%), Amblyomma ovale Koch (0.68%), Ixodes nr affinis (0.16%), Amblyomma nr maculatum (0.12%), and Amblyomma nr oblongoguttatum (0.12%). Ticks were pooled according to species, life stage (larva, nymph, or adult), and location (n = 509) for DNA extraction and screened for genus Rickettsia by quantitative real-time polymerase chain reaction (qPCR). All 42 positive pools were found to be positive for spotted fever group (SFG) Rickettsia in pools of A. cajennense complex (n = 33), A. maculatum (n = 4), A. nr maculatum (n = 1), A. ovale (n = 1), R. sanguineus (n = 1), and I. nr affinis (n = 2). Rickettsia amblyommatis was identified from A. cajennense complex and A. nr maculatum. Rickettsia parkeri was found in A. maculatum, and Rickettsia sp. endosymbiont was detected in I. nr affinis. The presence of infected ticks suggests a risk of tick-borne rickettsioses to humans and animals in Belize. This knowledge can contribute to an effective tick management and disease control program benefiting residents and travelers. Published by Oxford University Press on behalf of Entomological Society of America 2017. This work is written by US Government employees and is in the public domain in the US.

A strong-motion database from the Central American subduction zone

Science.gov (United States)

Arango, Maria Cristina; Strasser, Fleur O.; Bommer, Julian J.; Hernández, Douglas A.; Cepeda, Jose M.

2011-04-01

Subduction earthquakes along the Pacific Coast of Central America generate considerable seismic risk in the region. The quantification of the hazard due to these events requires the development of appropriate ground-motion prediction equations, for which purpose a database of recordings from subduction events in the region is indispensable. This paper describes the compilation of a comprehensive database of strong ground-motion recordings obtained during subduction-zone events in Central America, focusing on the region from 8 to 14° N and 83 to 92° W, including Guatemala, El Salvador, Nicaragua and Costa Rica. More than 400 accelerograms recorded by the networks operating across Central America during the last decades have been added to data collected by NORSAR in two regional projects for the reduction of natural disasters. The final database consists of 554 triaxial ground-motion recordings from events of moment magnitudes between 5.0 and 7.7, including 22 interface and 58 intraslab-type events for the time period 1976-2006. Although the database presented in this study is not sufficiently complete in terms of magnitude-distance distribution to serve as a basis for the derivation of predictive equations for interface and intraslab events in Central America, it considerably expands the Central American subduction data compiled in previous studies and used in early ground-motion modelling studies for subduction events in this region. Additionally, the compiled database will allow the assessment of the existing predictive models for subduction-type events in terms of their applicability for the Central American region, which is essential for an adequate estimation of the hazard due to subduction earthquakes in this region.

Herbarium specimens reveal the footprint of climate change on flowering trends across north-central North America.

Science.gov (United States)

Calinger, Kellen M; Queenborough, Simon; Curtis, Peter S

2013-08-01

Shifting flowering phenology with rising temperatures is occurring worldwide, but the rarity of co-occurring long-term observational and temperature records has hindered the evaluation of phenological responsiveness in many species and across large spatial scales. We used herbarium specimens combined with historic temperature data to examine the impact of climate change on flowering trends in 141 species collected across 116,000 km(2) in north-central North America. On average, date of maximum flowering advanced 2.4 days °C(-1), although species-specific responses varied from - 13.5 to + 7.3 days °C(-1). Plant functional types exhibited distinct patterns of phenological responsiveness with significant differences between native and introduced species, among flowering seasons, and between wind- and biotically pollinated species. This study is the first to assess large-scale patterns of phenological responsiveness with broad species representation and is an important step towards understanding current and future impacts of climate change on species performance and biodiversity. © 2013 The Authors. Ecology Letters published by John Wiley & Sons Ltd and CNRS.

Building America Industrialized Housing Partnership (BAIHP II)

Energy Technology Data Exchange (ETDEWEB)

Abernethy, Bob; Chandra, Subrato; Baden, Steven; Cummings, Jim; Cummings, Jamie; Beal, David; Chasar, David; Colon, Carlos; Dutton, Wanda; Fairey, Philip; Fonorow, Ken; Gil, Camilo; Gordon, Andrew; Hoak, David; Kerr, Ryan; Peeks, Brady; Kosar, Douglas; Hewes, Tom; Kalaghchy, Safvat; Lubliner, Mike; Martin, Eric; McIlvaine, Janet; Moyer, Neil; Liguori, Sabrina; Parker, Danny; Sherwin, John; Stroer, Dennis; Thomas-Rees, Stephanie; Daniel, Danielle; McIlvaine, Janet

2010-11-30

This report summarizes the work conducted by the Building America Industrialized Housing Partnership (BAIHP - www.baihp.org) during the final budget period (BP5) of our contract, January 1, 2010 to November 30, 2010. Highlights from the four previous budget periods are included for context. BAIHP is led by the Florida Solar Energy Center (FSEC) of the University of Central Florida. With over 50 Industry Partners including factory and site builders, work in BP5 was performed in six tasks areas: Building America System Research Management, Documentation and Technical Support; System Performance Evaluations; Prototype House Evaluations; Initial Community Scale Evaluations; Project Closeout, Final Review of BA Communities; and Other Research Activities.

A New Eocene Casquehead Lizard (Reptilia, Corytophanidae from North America.

Directory of Open Access Journals (Sweden)

Jack L Conrad

Full Text Available A new fossil showing affinities with extant Laemanctus offers the first clear evidence for a casquehead lizard (Corytophanidae from the Eocene of North America. Along with Geiseltaliellus from roughly coeval rocks in central Europe, the new find further documents the tropical fauna present during greenhouse conditions in the northern mid-latitudes approximately 50 million years ago (Ma. Modern Corytophanidae is a neotropical clade of iguanian lizards ranging from southern Mexico to northern South America.

Post-glacial phylogeography and evolution of a wide-ranging highly-exploited keystone forest tree, eastern white pine (Pinus strobus) in North America: single refugium, multiple routes.

Science.gov (United States)

Zinck, John W R; Rajora, Om P

2016-03-02

Knowledge of the historical distribution and postglacial phylogeography and evolution of a species is important to better understand its current distribution and population structure and potential fate in the future, especially under climate change conditions, and conservation of its genetic resources. We have addressed this issue in a wide-ranging and heavily exploited keystone forest tree species of eastern North America, eastern white pine (Pinus strobus). We examined the range-wide population genetic structure, tested various hypothetical population history and evolutionary scenarios and inferred the location of glacial refugium and post-glacial recolonization routes. Our hypothesis was that eastern white pine survived in a single glacial refugium and expanded through multiple post-glacial recolonization routes. We studied the range-wide genetic diversity and population structure of 33 eastern white pine populations using 12 nuclear and 3 chloroplast microsatellite DNA markers. We used Approximate Bayesian Computation approach to test various evolutionary scenarios. We observed high levels of genetic diversity, and significant genetic differentiation (F ST = 0.104) and population structure among eastern white pine populations across its range. A south to north trend of declining genetic diversity existed, consistent with repeated founder effects during post-glaciation migration northwards. We observed broad consensus from nuclear and chloroplast genetic markers supporting the presence of two main post-glacial recolonization routes that originated from a single southern refugium in the mid-Atlantic plain. One route gave rise to populations at the western margin of the species' range in Minnesota and western Ontario. The second route gave rise to central-eastern populations, which branched into two subgroups: central and eastern. We observed minimal sharing of chloroplast haplotypes between recolonization routes but there was evidence of admixture between the

Biogeographic range expansion into South America by Coccidioides immitis mirrors New World patterns of human migration

Science.gov (United States)

Fisher, Matthew C.; Koenig, Gina L.; White, Thomas J.; San-Blas, Gioconda; Negroni, Ricardo; Alvarez, Isidro Gutiérrez; Wanke, Bodo; Taylor, John W.

2001-01-01

Long-distance population dispersal leaves its characteristic signature in genomes, namely, reduced diversity and increased linkage between genetic markers. This signature enables historical patterns of range expansion to be traced. Herein, we use microsatellite loci from the human pathogen Coccidioides immitis to show that genetic diversity in this fungus is geographically partitioned throughout North America. In contrast, analyses of South American C. immitis show that this population is genetically depauperate and was founded from a single North American population centered in Texas. Variances of allele distributions show that South American C. immitis have undergone rapid population growth, consistent with an epidemic increase in postcolonization population size. Herein, we estimate the introduction into South America to have occurred within the last 9,000–140,000 years. This range increase parallels that of Homo sapiens. Because of known associations between Amerindians and this fungus, we suggest that the colonization of South America by C. immitis represents a relatively recent and rapid codispersal of a host and its pathogen. PMID:11287648

Homologous Recombination and Xylella fastidiosa Host-Pathogen Associations in South America.

Science.gov (United States)

Coletta-Filho, Helvécio D; Francisco, Carolina S; Lopes, João R S; Muller, Christiane; Almeida, Rodrigo P P

2017-03-01

Homologous recombination affects the evolution of bacteria such as Xylella fastidiosa, a naturally competent plant pathogen that requires insect vectors for dispersal. This bacterial species is taxonomically divided into subspecies, with phylogenetic clusters within subspecies that are host specific. One subspecies, pauca, is primarily limited to South America, with the exception of recently reported strains in Europe and Costa Rica. Despite the economic importance of X. fastidiosa subsp. pauca in South America, little is known about its genetic diversity. Multilocus sequence typing (MLST) has previously identified six sequence types (ST) among plant samples collected in Brazil (both subsp. pauca and multiplex). Here, we report on a survey of X. fastidiosa genetic diversity (MLST based) performed in six regions in Brazil and two in Argentina, by sampling five different plant species. In addition to the six previously reported ST, seven new subsp. pauca and two new subsp. multiplex ST were identified. The presence of subsp. multiplex in South America is considered to be the consequence of a single introduction from its native range in North America more than 80 years ago. Different phylogenetic approaches clustered the South American ST into four groups, with strains infecting citrus (subsp. pauca); coffee and olive (subsp. pauca); coffee, hibiscus, and plum (subsp. pauca); and plum (subsp. multiplex). In areas where these different genetic clusters occurred sympatrically, we found evidence of homologous recombination in the form of bidirectional allelic exchange between subspp. pauca and multiplex. In fact, the only strain of subsp. pauca isolated from a plum host had an allele that originated from subsp. multiplex. These signatures of bidirectional homologous recombination between endemic and introduced ST indicate that gene flow occurs in short evolutionary time frames in X. fastidiosa, despite the ecological isolation (i.e., host plant species) of genotypes.

Latin America Report, No. 2755.

Science.gov (United States)

1983-10-21

value of the cruzeiro may rise relative to European and Japanese currencies, "thus reducing the competitiveness of our products in those markets." At...The Tourist Office estimates that 21,600 people visited French Guiana in 1982, compared to 20,000 in 1981.* Hotel capacity is concentrated in ...their policy in Central America that has been repre- sented by the existence of the Contadora Group and the Declaration of Cancun . But there is

Pleurodese nos derrames pleurais malignos: um inquérito entre médicos em países da América do Sul e Central Pleurodesis for malignant pleural effusions: a survey of physicians in South and Central America

Directory of Open Access Journals (Sweden)

Evaldo Marchi

2010-12-01

Full Text Available OBJETIVO: A pleurodese é uma alternativa eficaz no controle dos derrames pleurais malignos, mas existem controvérsias a respeito de sua indicação e técnica. O objetivo deste estudo foi avaliar como é realizada a pleurodese em países da América do Sul e Central. MÉTODOS: Profissionais que realizam pleurodese responderam um questionário sobre critérios de indicação para pleurodese, técnicas utilizadas e desfechos. RESULTADOS: Nossa amostra envolveu 147 profissionais no Brasil, 49 em outros países da América do Sul e 36 em países da América Central. Mais de 50% dos participantes realizavam pleurodese somente se confirmada a malignidade no derrame pleural. Entretanto, escalas de dispneia e de status de performance eram raramente utilizadas para indicar o procedimento. Aproximadamente 75% dos participantes no Brasil e na América Central preferiam realizar a pleurodese somente no caso de recidiva do derrame, e a expansão pulmonar deveria variar de 90% a 100%. O talco slurry foi o agente mais utilizado, instilado via drenos de calibre intermediário. A toracoscopia foi realizada em menos de 25% dos casos. Febre e dor torácica foram os efeitos adversos mais comuns, e empiema ocorreu em OBJECTIVE: Pleurodesis is an effective alternative for the control of malignant pleural effusions. However, there is as yet no consensus regarding the indications for the procedure and the techniques employed therein. The objective of this study was to evaluate how pleurodesis is performed in South and Central America. METHODS: Professionals who perform pleurodesis completed a questionnaire regarding the indications for the procedure, the techniques used therein, and the outcomes obtained. RESULTS: Our sample comprised 147 respondents in Brazil, 49 in other South American countries, and 36 in Central America. More than 50% of the respondents reported performing pleurodesis only if pleural malignancy had been confirmed. However, scores on dyspnea and

"Wrecks of Ancient Life": Genetic Variants Vetted by Natural Selection.

Science.gov (United States)

Postlethwait, John H

2015-07-01

The Genetics Society of America's George W. Beadle Award honors individuals who have made outstanding contributions to the community of genetics researchers and who exemplify the qualities of its namesake as a respected academic, administrator, and public servant. The 2015 recipient is John Postlethwait. He has made groundbreaking contributions in developing the zebrafish as a molecular genetic model and in understanding the evolution of new gene functions in vertebrates. He built the first zebrafish genetic map and showed that its genome, along with that of distantly related teleost fish, had been duplicated. Postlethwait played an integral role in the zebrafish genome-sequencing project and elucidated the genomic organization of several fish species. Postlethwait is also honored for his active involvement with the zebrafish community, advocacy for zebrafish as a model system, and commitment to driving the field forward. Copyright © 2015 by the Genetics Society of America.

Mobile populations and HIV/AIDS in Central America and Mexico: research for action.

Science.gov (United States)

Bronfman, Mario N; Leyva, Rene; Negroni, Mirka J; Rueda, Celina M

2002-12-01

To present a multi-centre study that analyses the socioeconomic, cultural and political contexts that give rise to population mobility, and its relationship to vulnerability to sexually transmitted infections (STI)/HIV/AIDS, in order to provide information that can be used to design appropriate and focused interventions. In each of 11 transit stations (border towns, port cities, areas where mobile populations congregate) in Central America and Mexico, a household survey of the local population was conducted to analyse demographic, socioeconomic characteristics, and information known and opinions held about HIV/AIDS and mobile populations. In-depth interviews with key informants, community members and mobile populations were held to ascertain knowledge about prevention and transmission of STI/HIV/AIDS. Likewise, an ethnographic study was undertaken to identify interactions between local and mobile populations. The transit stations share low educational levels among the local population, few public services, repeated human rights violations, violence, poverty and corrupt authorities. Within this social context, transactional sex, sex for survival, rape and non-professional commercial sex happen in conditions that increase the risk of the transmission of STI/HIV, such as infrequent condom use. Migrant women and sex workers are particularly vulnerable in this context. A wide gap exists between information about STI/HIV transmission and reported prevention practices. Given the conditions that exist in these transit stations, interventions should be multisectoral, sustainable, and should defend the human rights of various groups, including women and people living with HIV/AIDS.

The Latin-American region and the challenges to develop one homogeneous and harmonized hazard model: preliminary results for the Caribbean and Central America regions in the GEM context

Science.gov (United States)

Garcia, J.; Arcila, M.; Benito, B.; Eraso, J.; García, R.; Gomez Capera, A.; Pagani, M.; Pinho, R.; Rendon, H.; Torres, Y.

2013-05-01

Latin America is a seismically active region with complex tectonic settings that make the creation of hazard models challenging. Over the past two decades PSHA studies have been completed for this region in the context of global (Shedlock, 1999), regional (Dimaté et al., 1999) and national initiatives. Currently different research groups are developing new models for various nations. The Global Earthquake Model (GEM), an initiative aiming at the creation of a large global community working collaboratively on building hazard and risk models using open standards and tools, is promoting the collaboration between different national projects and groups so as to facilitate the creation of harmonized regional models. The creation of a harmonized hazard model can follow different approaches, varying from a simple patching of available models to a complete homogenisation of basic information and the subsequent creation of a completely new PSHA model. In this contribution we describe the process and results of a first attempt aiming at the creation of a community based model covering the Caribbean and Central America regions. It consists of five main steps: 1- Identification and collection of available PSHA input models; 2- Analysis of the consistency, transparency and reproducibility of each model; 3- Selection (if more then a model exists for the same region); 4- Representation of the models in a standardized format and incorporation of new knowledge from recent studies; 5- Proposal(s) of harmonization We consider some PHSA studies completed over the latest twenty years in the region comprising the Caribbean (CAR), Central America (CAM) and northern South America (SA), we illustrate a tentative harmonization of the seismic source geometries models and we discuss the steps needed toward a complete harmonisation of the models. Our will is to have a model based on best practices and high standards created though a combination of knowledge and competences coming from the

Assessment of clinical efficacy and safety in a randomized double-blind study of etanercept and sulfasalazine in patients with ankylosing spondylitis from Eastern/Central Europe, Latin America, and Asia.

Science.gov (United States)

Damjanov, Nemanja; Shehhi, Waleed Al; Huang, Feng; Kotak, Sameer; Burgos-Vargas, Ruben; Shirazy, Khalid; Bananis, Eustratios; Szumski, Annette; Llamado, Lyndon J Q; Mahgoub, Ehab

2016-05-01

Despite the demonstrated efficacy of etanercept for the treatment of ankylosing spondylitis (AS), sulfasalazine is often prescribed, especially in countries with limited access to biologic agents. The objective of this subset analysis of the ASCEND trial was to compare the efficacy of etanercept and sulfasalazine in treating patients with AS from Asia, Eastern/Central Europe, and Latin America. A total of 287 patients, 190 receiving etanercept 50 mg once weekly and 97 receiving sulfasalazine 3 g daily, from eight countries were included in this subset analysis. Differences in disease activity and patient-reported outcomes assessing health-related quality-of-life (HRQoL) parameters in response to treatment were analyzed using the Cochran-Mantel-Haenszel test for categorical efficacy endpoints and analysis of covariance model for continuous variables. At week 16, a significantly greater proportion of patients receiving etanercept achieved ASAS20 (79.0 %) compared with patients receiving sulfasalazine (61.9 %; p = 0.002). At week 16, treatment with etanercept also resulted in significantly better responses than sulfasalazine for ASAS40 (64.7 vs. 35.1 %; p Disease Activity Index (65.8 vs. 42.3 %; p Asia, Central/Eastern Europe, and Latin America.

Use of nuclear and related techniques in studies of agroecological effects resulting from the use of persistent pesticides in Central America. Report of a final research co-ordination meeting

International Nuclear Information System (INIS)

1999-09-01

The use of pesticides for the control of pests of agriculture and vectors of human and animal diseases in the countries of Central America is the highest per capita and one of the most intense in the world. There are reports of acute toxicity and chronic effects among farm workers. There are also reports that pesticide residues in food frequently exceed the Codex Alimentarius Commission's maximum residue levels (MRLs) and shipments of foodstuffs have been rejected by importing countries due to the presence of excessive residues of pesticides. Pesticides are also implicated in the contamination of continental and coastal waters. The indiscriminate use of pesticides would be expected to also aggravate pest problems by adversely affecting populations of beneficial arthropods and causing the development of resistance in pest populations. The Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture initiated a co-ordinated research project in 1992 to generate information on residues of pesticides in the environment, their persistence under local conditions and effect on local species of beneficial arthropods in agricultural and adjacent areas in the countries of Central America. Such information could be used in the implementation of legislation to control the distribution and use of pesticides and the development and application of integrated pest management programmes. Scientists from Costa Rica, Guatemala, Honduras, Nicaragua, Panama and the United States of America participated in this project. This TECDOC reports on the accomplishments of the project and includes the papers presented at the final Research Co-ordination Meeting held in Panama City, Panama, 20-24 April 1998

Impacts of Central American Fires on Ozone Air Quality along the US Gulf Coast

Science.gov (United States)

Wang, S. C.; Wang, Y.; Estes, M. J.; Lei, R.; Talbot, R. W.

2017-12-01

Biomass burning in Central America is associated with agriculture activities and occurs regularly during April and May every year. Satellite observations have documented frequent transport of wildfire smoke from Mexico and Central America to the southern US, causing haze and exceedance of fine particle matter. However, the impacts of those fires on surface ozone in the US are poorly understood. This study uses both observations and modeling to examine the effects of the springtime Central America fire emissions on surface ozone over the Gulf coastal regions over a long-term time period (2002-2015). Passive tracer simulation in the nested-grid version of the GEOS-Chem chemical transport model over North America is used to identify the days when Central American fire plumes reached the US Gulf Coast. During the identified fire-impact days, Central American fires are estimated to result in an average of 9 ppbv enhancement of regional background ozone over the Houston-Galveston-Brazoria (HGB) region. Satellite-observed distributions of AOD and CO are used to examine the transport pathways and effects of those fires on atmospheric composition. Finally, we integrate satellite observations, ground measurements, and modeling to quantify the impact of Central American fires on springtime ozone air quality along the US Gulf Coast in terms of both long-term (2002-2015) mean and extreme cases.

Status of soil acidification in North America

Science.gov (United States)

M. E. Fenn; T. G. Huntington; S. B. McLaughlin; C. Eagar; A. Gomez; R. B. Cook

2006-01-01

Forest soil acidification and depletion of nutrient cations have been reported for several forested regions in North America, predominantly in the eastern United States, including the northeast and in the central Appalachians, but also in parts of southeastern Canada and the southern U.S. Continuing regional inputs of nitrogen and sulfur are of concern because of...

Geologic literature on North America, 1785-1918; Part I, Bibliography

Science.gov (United States)

Nickles, John M.

1923-01-01

The bibliography forming Part I of this compilation includes papers relating to the geology paleontology, petrology, and mineralogy of North America-specifically, the United States, the Dominion of Canada and Newfoundland, the Arctic regions north of the continent, Greenland, Mexico Central America, Panama, and the West Indies including Trinidad-and also the Hawaiian Islands. Geographic and descriptive writings and accounts of travels with incidental mention of geologic facts are not included. Textbooks published in America and work general in character by American authors are given but general papers by foreign writers are excluded unless they have appeared in American publications. Papers by American writers on the geology of other parts of the world are not listed.

Phylogeography of the Central American lancehead Bothrops asper (SERPENTES: VIPERIDAE)

Science.gov (United States)

Parkinson, Christopher L.; Daza, Juan M.; Wüster, Wolfgang

2017-01-01

The uplift and final connection of the Central American land bridge is considered the major event that allowed biotic exchange between vertebrate lineages of northern and southern origin in the New World. However, given the complex tectonics that shaped Middle America, there is still substantial controversy over details of this geographical reconnection, and its role in determining biogeographic patterns in the region. Here, we examine the phylogeography of Bothrops asper, a widely distributed pitviper in Middle America and northwestern South America, in an attempt to evaluate how the final Isthmian uplift and other biogeographical boundaries in the region influenced genealogical lineage divergence in this species. We examined sequence data from two mitochondrial genes (MT-CYB and MT-ND4) from 111 specimens of B. asper, representing 70 localities throughout the species’ distribution. We reconstructed phylogeographic patterns using maximum likelihood and Bayesian methods and estimated divergence time using the Bayesian relaxed clock method. Within the nominal species, an early split led to two divergent lineages of B. asper: one includes five phylogroups distributed in Caribbean Middle America and southwestern Ecuador, and the other comprises five other groups scattered in the Pacific slope of Isthmian Central America and northwestern South America. Our results provide evidence of a complex transition that involves at least two dispersal events into Middle America during the final closure of the Isthmus. PMID:29176806

Archaeological support for the three-stage expansion of modern humans across northeastern Eurasia and into the Americas.

Science.gov (United States)

Hamilton, Marcus J; Buchanan, Briggs

2010-08-30

Understanding the dynamics of the human range expansion across northeastern Eurasia during the late Pleistocene is central to establishing empirical temporal constraints on the colonization of the Americas. Opinions vary widely on how and when the Americas were colonized, with advocates supporting either a pre- or post- last glacial maximum (LGM) colonization, via either a land bridge across Beringia, a sea-faring Pacific Rim coastal route, a trans-Arctic route, or a trans-Atlantic oceanic route. Here we analyze a large sample of radiocarbon dates from the northeast Eurasian Upper Paleolithic to identify the origin of this expansion, and estimate the velocity of colonization wave as it moved across northern Eurasia and into the Americas. We use diffusion models to quantify these dynamics. Our results show the expansion originated in the Altai region of southern Siberia approximately 46kBP , and from there expanded across northern Eurasia at an average velocity of 0.16 km per year. However, the movement of the colonizing wave was not continuous but underwent three distinct phases: 1) an initial expansion from 47-32k calBP; 2) a hiatus from approximately 32-16k calBP, and 3) a second expansion after the LGM approximately 16k calBP. These results provide archaeological support for the recently proposed three-stage model of the colonization of the Americas. Our results falsify the hypothesis of a pre-LGM terrestrial colonization of the Americas and we discuss the importance of these empirical results in the light of alternative models. Our results demonstrate that the radiocarbon record of Upper Paleolithic northeastern Eurasia supports a post-LGM terrestrial colonization of the Americas falsifying the proposed pre-LGM terrestrial colonization of the Americas. We show that this expansion was not a simple process, but proceeded in three phases, consistent with genetic data, largely in response to the variable climatic conditions of late Pleistocene northeast Eurasia

Efficacy and safety of etanercept in patients from Latin America, Central Europe and Asia with early non-radiographic axial spondyloarthritis.

Science.gov (United States)

Wei, James Cheng-Chung; Tsai, Wen-Chan; Citera, Gustavo; Kotak, Sameer; Llamado, Lyndon

2016-11-11

To evaluate etanercept in patients from Latin America, Central/Eastern Europe, and Asia with non-radiographic axial spondyloarthritis (nr-axSpA). A subset analysis was performed on nr-axSpA patients from Argentina, Colombia, the Czech Republic, Hungary, Russia and Taiwan who were enrolled in EMBARK (NCT01258738). Patients received either etanercept 50 mg or placebo once weekly. The primary endpoint was proportion of patients achieving 40% improvement from baseline based on Assessment of SpondyloArthritis International Society (ASAS) criteria. Secondary endpoints included other efficacy assessments, health-related quality of life (HRQoL) and safety. Of the 117 patients in this subset, 59 were treated with etanercept and 58 received placebo. At week 12, numerically greater improvements from baseline were observed for all efficacy endpoints in etanercept-treated patients compared with those receiving placebo. Statistically significant differences between the two treatment groups were observed for proportion of patients achieving ASAS40 (P = 0.0413, at week 8), ASAS5/6 (P = 0.0126), Ankylosing Spondylitis Disease Activity Score - C-reactive protein (CRP) inactive disease (P = 0.0093), Spondyloarthritis Research Consortium of Canada magnetic resonance imaging of sacroiliac joint scores (P = 0.0014), high-sensitivity CRP (P=0.032), and erythrocyte sedimentation rate (P = 0.0082). Statistically significant improvements in the etanercept-treated group compared with placebo group were observed for nocturnal back pain (P = 0.040), total back pain (P = 0.025), physician global assessment of disease (P = 0.023), and Work Productivity and Activity Impairment Questionnaire percent impairment while working (P = 0.047). Adverse events were similar between the two treatment groups. In this subset of patients with nr-axSpA from Latin America, Central/Eastern Europe, and Asia, treatment with etanercept, compared with placebo, resulted in improved disease symptoms and patient HRQo

Genetic structure analysis of Spirometra erinaceieuropaei isolates from central and southern China.

Directory of Open Access Journals (Sweden)

Xi Zhang

Full Text Available Sparganosis caused by invasion of the plerocercoid larvae (spargana of Spirometra erinaceieuropaei have increased in recent years in China. However, the population genetic structure regarding this parasite is still unclear. In this study, we used the sequences of two mitochondrial genes cytochrome b (cytb and cytochrome c oxidase subunit I (cox1 to analyze genetic variation and phylogeographic structure of the S. erinaceieuropaei populations.A total of 88 S. erinaceieuropaei isolates were collected from naturally infected frogs in 14 geographical locations of China. The complete cytb and cox1 genes of each sample was amplified and sequenced. Total 61 haplotypes were found in these 88 concatenated sequences. Each sampled population and the total population have high haplotype diversity (Hd, accompanied by very low nucleotide diversity (Pi. Phylogenetic analyses of haplotypes revealed two distinct clades (HeN+HuN+GZ-AS clade and GX+HN+GZ-GY clade corresponding two sub-networks yielded by the median-joining network. Pairwise FST values supported great genetic differentiation between S. erinaceieuropaei populations. Both negative Fu's FS value of neutrality tests and unimodal curve of mismatch distribution analyses supported demographic population expansion in the HeN+HuN+GZ-AS clade. The BEAST analysis showed that the divergence time between the two clades took place in the early Pleistocene (1.16 Myr, and by Bayesian skyline plot (BSP an expansion occurred after about 0.3 Myr ago.S. erinaceieuropaei from central and southern China has significant phylogeographic structure, and climatic oscillations during glacial periods in the Quaternary may affect the demography and diversification of this species.

[Agrarian movements, development alternatives and food security in Central America: scenarios of transition].

Science.gov (United States)

Rodriguez Rojas, R

1991-01-01

This article, based on personal experiences with a network of organizations of small and medium agricultural producers in Central America, aims to present the views of peasant organizations concerning agrarian problems in the region. The 3 major sections of work define the place of peasant agriculture in the traditional agrarian structure and the new problems resulting from the structural adjustment programs of the 1980s; separately describe the new peasant movements emerging in Honduras, El Salvador, Nicaragua, Costa Rica, and Panama, identifying common themes an efforts at international collaboration; and explore the positions of the peasant organizations on the optimal strategies for agricultural development and agrarian change. Agriculture remains the backbone of the Central American economies. But because the economic model in the region is 1 of accumulation characterized by dependency, concentration of capital, and social marginalization, the agrarian structure is at the basis of social tensions. Efforts to develop peasant agriculture and to give small producers access to marketing and credit services have been weak and sporadic. The new peasant movements are less inclined than those of the past to employ tactics of confrontation in their efforts to secure access to land and better working conditions. The new movement is the expression of small market producers sometimes grouped into associations who are oriented to production of basic foodstuffs for the internal market. A new concern with adaptation and negotiation is evident. The new organizations have in common a belief in their ability to propose new solutions to regional problems. Their views are founded on a positive assessment of the ability of peasant agriculture to produce food and add dynamism to the regional economy after barriers to credit, technological progress, and modernization in general are removed. Signs of increased cooperation are evident between peasant organizations and other groups

Climate oscillations, glacial refugia, and dispersal ability: factors influencing the genetic structure of the least salmonfly, Pteronarcella badia (Plecoptera), in Western North America.

Science.gov (United States)

Sproul, John S; Houston, Derek D; Nelson, C Riley; Evans, R Paul; Crandall, Keith A; Shiozawa, Dennis K

2015-12-12

Phylogeographic studies of aquatic insects provide valuable insights into mechanisms that shape the genetic structure of communities, yet studies that include broad geographic areas are uncommon for this group. We conducted a broad scale phylogeographic analysis of the least salmonfly Pteronarcella badia (Plecoptera) across western North America. We tested hypotheses related to mode of dispersal and the influence of historic climate oscillations on population genetic structure. In order to generate a larger mitochondrial data set, we used 454 sequencing to reconstruct the complete mitochondrial genome in the early stages of the project. Our analysis revealed high levels of population structure with several deeply divergent clades present across the sample area. Evidence from five mitochondrial genes and one nuclear locus identified a potentially cryptic lineage in the Pacific Northwest. Gene flow estimates and geographic clade distributions suggest that overland flight during the winged adult stage is an important dispersal mechanism for this taxon. We found evidence of multiple glacial refugia across the species distribution and signs of secondary contact within and among major clades. This study provides a basis for future studies of aquatic insect phylogeography at the inter-basin scale in western North America. Our findings add to an understanding of the role of historical climate isolations in shaping assemblages of aquatic insects in this region. We identified several geographic areas that may have historical importance for other aquatic organisms with similar distributions and dispersal strategies as P. badia. This work adds to the ever-growing list of studies that highlight the potential of next-generation DNA sequencing in a phylogenetic context to improve molecular data sets from understudied groups.

Analysis of genetic diversity and differentiation of seven stocks of Litopenaeus vannamei using microsatellite markers

Science.gov (United States)

Zhang, Kai; Wang, Weiji; Li, Weiya; Zhang, Quanqi; Kong, Jie

2014-08-01

Seven microsatellite markers were used to evaluate the genetic diversity and differentiation of seven stocks of Litopenaeus vannamei, which were introduced from Central and South America to China. All seven microsatellite loci were polymorphic, with polymorphism information content ( PIC) values ranging from 0.593 to 0.952. Totally 92 alleles were identified, and the number of alleles ( Na) and effective alleles ( Ne) varied between 4 and 21 and 2.7 and 14.6, respectively. Observed heterozygosity ( H o) values were lower than the expected heterozygosity ( H e) values (0.526-0.754), which indicated that the seven stocks possessed a rich genetic diversity. Thirty-seven tests were detected for reasonable significant deviation from Hardy-Weinberg equilibrium. F is values were positive at five loci, suggesting that there was a relatively high degree of inbreeding within stocks. Pairwise F st values ranged from 0.0225 to 0.151, and most of the stock pairs were moderately differentiated. Genetic distance and cluster analysis using UPGMA revealed a close genetic relationship of L. vannamei between Pop2 and Pop3. AMOVA indicated that the genetic variation among stocks (11.3%) was much lower than that within stocks (88.7%). Although the seven stocks had a certain degree of genetic differentiation and a rich genetic diversity, there is an increasing risk of decreased performance due to inbreeding in subsequent generations.

Genetic variation among the Mapuche Indians from the Patagonian region of Argentina: mitochondrial DNA sequence variation and allele frequencies of several nuclear genes.

Science.gov (United States)

Ginther, C; Corach, D; Penacino, G A; Rey, J A; Carnese, F R; Hutz, M H; Anderson, A; Just, J; Salzano, F M; King, M C

1993-01-01

DNA samples from 60 Mapuche Indians, representing 39 maternal lineages, were genetically characterized for (1) nucleotide sequences of the mtDNA control region; (2) presence or absence of a nine base duplication in mtDNA region V; (3) HLA loci DRB1 and DQA1; (4) variation at three nuclear genes with short tandem repeats; and (5) variation at the polymorphic marker D2S44. The genetic profile of the Mapuche population was compared to other Amerinds and to worldwide populations. Two highly polymorphic portions of the mtDNA control region, comprising 650 nucleotides, were amplified by the polymerase chain reaction (PCR) and directly sequenced. The 39 maternal lineages were defined by two or three generation families identified by the Mapuches. These 39 lineages included 19 different mtDNA sequences that could be grouped into four classes. The same classes of sequences appear in other Amerinds from North, Central, and South American populations separated by thousands of miles, suggesting that the origin of the mtDNA patterns predates the migration to the Americas. The mtDNA sequence similarity between Amerind populations suggests that the migration throughout the Americas occurred rapidly relative to the mtDNA mutation rate. HLA DRB1 alleles 1602 and 1402 were frequent among the Mapuches. These alleles also occur at high frequency among other Amerinds in North and South America, but not among Spanish, Chinese or African-American populations. The high frequency of these alleles throughout the Americas, and their specificity to the Americas, supports the hypothesis that Mapuches and other Amerind groups are closely related.(ABSTRACT TRUNCATED AT 250 WORDS)

Genetic calibration of species diversity among North America's freshwater fishes

OpenAIRE

April, Julien; Mayden, Richard L.; Hanner, Robert H.; Bernatchez, Louis

2011-01-01

Freshwater ecosystems are being heavily exploited and degraded by human activities all over the world, including in North America, where fishes and fisheries are strongly affected. Despite centuries of taxonomic inquiry, problems inherent to species identification continue to hamper the conservation of North American freshwater fishes. Indeed, nearly 10% of species diversity is thought to remain undescribed. To provide an independent calibration of taxonomic uncertainty and to establish a mor...

Fermilab and Latin America

International Nuclear Information System (INIS)

Lederman, Leon M.

2006-01-01

As Director of Fermilab, starting in 1979, I began a series of meetings with scientists in Latin America. The motivation was to stir collaboration in the field of high energy particle physics, the central focus of Fermilab. In the next 13 years, these Pan American Symposia stirred much discussion of the use of modern physics, created several groups to do collaborative research at Fermilab, and often centralized facilities and, today, still provides the possibility for much more productive North-South collaboration in research and education. In 1992, I handed these activities over to the AAAS, as President. This would, I hoped, broaden areas of collaboration. Such collaboration is unfortunately very sensitive to political events. In a rational world, it would be the rewards, cultural and economic, of collaboration that would modulate political relations. We are not there yet

Chum and pink salmon genetics - Genetic and life history variation of southern chum and pink salmon

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The distribution of genetic and life history variation in chum (Oncorhynchus keta) and pink (O. gorbuscha) salmon in their southern range in North America is key to...

From violence to more violence in Central America

Directory of Open Access Journals (Sweden)

Israel Medina

2014-11-01

Full Text Available Many Central American migrants flee their home country as a result of violence and threats from the criminal gangs. A large number of them also encounter the same type of violence that they are fleeing when on the migratory routes through Mexico.

Climate Impacts of Deforestation/Land-Use Changes in Central South America in the PRECIS Regional Climate Model: Mean Precipitation and Temperature Response to Present and Future Deforestation Scenarios

OpenAIRE

Pablo O. Canziani; Gerardo Carbajal Benitez

2012-01-01

Deforestation/land-use changes are major drivers of regional climate change in central South America, impacting upon Amazonia and Gran Chaco ecoregions. Most experimental and modeling studies have focused on the resulting perturbations within Amazonia. Using the Regional Climate Model PRECIS, driven by ERA-40 reanalysis and ECHAM4 Baseline model for the period 1961–2000 (40-year runs), potential effects of deforestation/land-use changes in these and other neighboring ecoregions are evaluated....

Mitochondrial DNA variability among eight Tikúna villages: evidence for an intratribal genetic heterogeneity pattern.

Science.gov (United States)

Mendes-Junior, Celso Teixeira; Simões, Aguinaldo Luiz

2009-11-01

To study the genetic structure of the Tikúna tribe, four major Native American mitochondrial DNA (mtDNA) founder haplogroups were analyzed in 187 Amerindians from eight Tikúna villages located in the Brazilian Amazon. The central position of these villages in the continent makes them relevant for attempts to reconstruct population movements in South America. In this geographic region, there is particular concern regarding the genetic structure of the Tikúna tribe, formerly designated "enigmatic" due to its remarkable degree of intratribal homogeneity and the scarcity of private protein variants. In spite of its large population size and geographic distribution, the Tikúna tribe presents marked genetic and linguistic isolation. All individuals presented indigenous mtDNA haplogroups. An intratribal genetic heterogeneity pattern characterized by two highly homogeneous Tikúna groups that differ considerably from each other was observed. Such a finding was unexpected, since the Tikúna tribe is characterized by a social system that favors intratribal exogamy and patrilocality that would lead to a higher female migration rate and homogenization of the mtDNA gene pool. Demographic explosions and religious events, which significantly changed the sizes and compositions of many Tikúna villages, may be reflected in the genetic results presented here.

300 years of hydrological records and societal responses to droughts and floods on the Pacific coast of Central America

Science.gov (United States)

Guevara-Murua, Alvaro; Williams, Caroline A.; Hendy, Erica J.; Imbach, Pablo

2018-02-01

The management of hydrological extremes and impacts on society is inadequately understood because of the combination of short-term hydrological records, an equally short-term assessment of societal responses and the complex multi-directional relationships between the two over longer timescales. Rainfall seasonality and inter-annual variability on the Pacific coast of Central America is high due to the passage of the Inter Tropical Convergence Zone (ITCZ) and the El Niño-Southern Oscillation (ENSO). Here we reconstruct hydrological variability and demonstrate the potential for assessing societal impacts by drawing on documentary sources from the cities of Santiago de Guatemala (now Antigua Guatemala) and Guatemala de la Asunción (now Guatemala City) over the period from 1640 to 1945. City and municipal council meetings provide a rich source of information dating back to the beginning of Spanish colonisation in the 16th century. We use almost continuous sources from 1640 AD onwards, including > 190 volumes of Actas de Cabildo and Actas Municipales (minutes of meetings of the city and municipal councils) held by the Archivo Histórico de la Municipalidad de Antigua Guatemala (AHMAG) and the Archivo General de Centro América (AGCA) in Guatemala City. For this 305-year period (with the exception of a total of 11 years during which the books were either missing or damaged), information relating to Catholic rogation ceremonies and reports of flooding events and crop shortages were used to classify the annual rainy season (May to October) on a five-point scale from very wet to very dry. In total, 12 years of very wet conditions, 25 years of wetter than usual conditions, 34 years of drier conditions and 21 years of very dry conditions were recorded. An extended drier period from the 1640s to the 1740s was identified and two shorter periods (the 1820s and the 1840s) were dominated by dry conditions. Wetter conditions dominated the 1760s-1810s and possibly record more

Characterization of the genetic diversity of Mycobacterium tuberculosis in São Paulo city, Brazil.

Science.gov (United States)

Mendes, Natália H; Melo, Fernando Af; Santos, Adolfo Cb; Pandolfi, José Rc; Almeida, Elisabete A; Cardoso, Rosilene F; Berghs, Henri; David, Suzana; Johansen, Faber K; Espanha, Lívia G; Leite, Sergio Ra; Leite, Clarice Qf

2011-07-29

Tuberculosis is a major health problem in São Paulo, Brazil, which is the most populous and one of the most cosmopolitan cities in South America. To characterize the genetic diversity of Mycobacterium tuberculosis in the population of this city, the genotyping techniques of spoligotyping and MIRU were applied to 93 isolates collected in two consecutive years from 93 different tuberculosis patients residing in São Paulo city and attending the Clemente Ferreira Institute (the reference clinic for the treatment of tuberculosis). Spoligotyping generated 53 different spoligotype patterns. Fifty-one isolates (54.8%) were grouped into 13 spoligotyping clusters. Seventy- two strains (77.4%) showed spoligotypes described in the international databases (SpolDB4, SITVIT), and 21 (22.6%) showed unidentified patterns. The most frequent spoligotype families were Latin American Mediterranean (LAM) (26 isolates), followed by the T family (24 isolates) and Haarlem (H) (11 isolates), which together accounted for 65.4% of all the isolates. These three families represent the major genotypes found in Africa, Central America, South America and Europe. Six Spoligo-International-types (designated SITs by the database) comprised 51.8% (37/72) of all the identified spoligotypes (SIT53, SIT50, SIT42, SIT60, SIT17 and SIT1). Other SITs found in this study indicated the great genetic diversity of M. tuberculosis, reflecting the remarkable ethnic diversity of São Paulo city inhabitants. The MIRU technique was more discriminatory and did not identify any genetic clusters with 100% similarity among the 93 isolates. The allelic analysis showed that MIRU loci 26, 40, 23 and 10 were the most discriminatory. When MIRU and spoligotyping techniques were combined, all isolates grouped in the 13 spoligotyping clusters were separated. Our data indicated the genomic stability of over 50% of spoligotypes identified in São Paulo and the great genetic diversity of M. tuberculosis isolates in the remaining

Characterization of the genetic diversity of Mycobacterium tuberculosis in São Paulo city, Brazil

Directory of Open Access Journals (Sweden)

Espanha Lívia G

2011-07-01

Full Text Available Abstract Background Tuberculosis is a major health problem in São Paulo, Brazil, which is the most populous and one of the most cosmopolitan cities in South America. To characterize the genetic diversity of Mycobacterium tuberculosis in the population of this city, the genotyping techniques of spoligotyping and MIRU were applied to 93 isolates collected in two consecutive years from 93 different tuberculosis patients residing in São Paulo city and attending the Clemente Ferreira Institute (the reference clinic for the treatment of tuberculosis. Findings Spoligotyping generated 53 different spoligotype patterns. Fifty-one isolates (54.8% were grouped into 13 spoligotyping clusters. Seventy- two strains (77.4% showed spoligotypes described in the international databases (SpolDB4, SITVIT, and 21 (22.6% showed unidentified patterns. The most frequent spoligotype families were Latin American Mediterranean (LAM (26 isolates, followed by the T family (24 isolates and Haarlem (H (11 isolates, which together accounted for 65.4% of all the isolates. These three families represent the major genotypes found in Africa, Central America, South America and Europe. Six Spoligo-International-types (designated SITs by the database comprised 51.8% (37/72 of all the identified spoligotypes (SIT53, SIT50, SIT42, SIT60, SIT17 and SIT1. Other SITs found in this study indicated the great genetic diversity of M. tuberculosis, reflecting the remarkable ethnic diversity of São Paulo city inhabitants. The MIRU technique was more discriminatory and did not identify any genetic clusters with 100% similarity among the 93 isolates. The allelic analysis showed that MIRU loci 26, 40, 23 and 10 were the most discriminatory. When MIRU and spoligotyping techniques were combined, all isolates grouped in the 13 spoligotyping clusters were separated. Conclusions Our data indicated the genomic stability of over 50% of spoligotypes identified in São Paulo and the great genetic

Genetics Home Reference: congenital central hypoventilation syndrome

Science.gov (United States)

... Kravis EM, Zhou L, Rand CM, Weese-Mayer DE. Congenital central hypoventilation syndrome: PHOX2B mutations and phenotype. Am J Respir Crit ... BA, Leurgans SE, Berry-Kravis EM, Weese-Mayer DE. Congenital central hypoventilation syndrome: PHOX2B genotype determines risk for sudden death. Pediatr ...

Implications of the Central America-Dominican Republic-Free Trade Agreement for the nutrition transition in Central America Implicaciones del Tratado de Libre Comercio entre Centroamérica y República Dominicana sobre la transición alimentaria en Centroamérica

Directory of Open Access Journals (Sweden)

Corinna Hawkes

2008-11-01

Full Text Available OBJECTIVES: To identify potential impacts of the Central America-Dominican Republic-Free Trade Agreement (CAFTA-DR on food consumption patterns associated with the nutrition transition, obesity, and diet-related chronic diseases. METHODS: Examination of CAFTA-DR agreement to identify measures that have the potential to affect food availability and retail prices. RESULTS: CAFTA-DR includes agreements on tariffs, tariff-rate quotas (TRQs, and sanitary and phytosanitary regulations with direct implications for the availability and prices of various foods. Agreements on investment, services, and intellectual property rights (IPR are also relevant because they create a business climate more conducive to long-term investment by the transnational food industry. Trade liberalization under CAFTA-DR is likely to increase availability and lower relative prices of two food groups associated with the nutrition transition: meat and processed foods. These outcomes are expected to occur as the direct result of increased imports from the United States and increased production by U.S. companies based in Central America, and the indirect result of increased domestic meat production (due to increased availability of cheaper animal feed and increased production of processed foods by domestic companies (due to a more competitive market environment. CONCLUSIONS: CAFTA-DR is likely to further the nutrition transition in Central America by increasing the consumption of meat; highly processed foods; and new, non-traditional foods. The public health community should be more aware of the implications of trade agreements for dietary health. Governments and related stakeholders should assess the coherence between changes fostered by specific trade agreements with national policies on diet and nutrition.OBJETIVOS: Identificar el posible impacto del Tratado de Libre Comercio entre Centroamérica y República Dominicana (TLCCA-RD sobre el patrón de consumo de alimentos

Phylogenetics of Ogyges Kaup and the biogeography of Nuclear Central America (Coleoptera, Passalidae)

Science.gov (United States)

Cano, Enio B.; Schuster, Jack C.; Morrone, Juan J.

2018-01-01

Abstract A phylogenetic morphological analysis of the genus Ogyges Kaup, distributed in Nuclear Central America, from Chiapas, Mexico, to northwestern Nicaragua was undertaken. Five species of Proculejus Kaup, distributed north of the Isthmus of Tehuantepec in Mexico, were selected as outgroup. Ogyges was recovered as monophyletic with three species groups: championi, laevissimus, and crassulus. Each species group shows a distinct, generally allopatric distribution. The O. championi species group, with ten species, is distributed in the Maya block, more specifically in the mountainous system north of the Motozintla-Comaltitlán fault in Chiapas, and north of the dry valleys of the Cuilco and Motagua rivers in Guatemala. The two remaining species groups are distributed in the Chortis block. The O. laevissimus species group, including seven species, ranges mostly along the Pacific Volcanic Chain from Guatemala to El Salvador, and from southeastern Honduras to the northwestern area of Nicaragua. The O. crassulus species group, with ten species, is distributed from northeastern Guatemala (Merendón) to northern Honduras. The Isthmus of Tehuantepec in Mexico, the Motagua-Cuilco and Motozintla-Comaltitlán sutures zones in Chiapas and Guatemala, the lowland valleys of Colón and Comalí rivers between Nicaragua and Honduras (or, perhaps, the northern suture of the Siuna Terrane in Nicaragua), the Guayape fault system in Honduras, and the intricate dry valleys of Ulúa-Chamelecón-Olancho in Honduras, are hypothesized to have acted as barriers that affected the geographical distribution of Ogyges, as well as probably other montane organisms. PMID:29674874

Temporal diversification of Central American cichlids

Directory of Open Access Journals (Sweden)

Hulsey C Darrin

2010-09-01

Full Text Available Abstract Background Cichlid fishes are classic examples of adaptive radiation because of their putative tendency to explosively diversify after invading novel environments. To examine whether ecological opportunity increased diversification (speciation minus extinction early in a species-rich cichlid radiation, we determined if Heroine cichlids experienced a burst of diversification following their invasion of Central America. Results We first reconstructed the Heroine phylogeny and determined the basal node to use as the root of Central American Heroine diversification. We then examined the influence of incomplete taxon sampling on this group's diversification patterns. First, we added missing species randomly to the phylogeny and assessed deviations from a constant rate of lineage accumulation. Using a range of species numbers, we failed to recover significant deviations from a pure-birth process and found little support for an early burst of diversification. Then, we examined patterns of lineage accumulation as nodes were increasingly truncated. We assumed that as we removed more recently diverged lineages that sampling would become more complete thereby increasing the power to detect deviations from a pure-birth model. However, truncation of nodes provided even less support for an early burst of diversification. Conclusions Contrary to expectations, our analyses suggest Heroine cichlids did not undergo a burst of diversification when they invaded from South America. Throughout their history in Central America, Heroine cichlids appear to have diversified at a constant rate.

Central Bank independence in Latin America La independencia de la Banca Central en América Latina

Directory of Open Access Journals (Sweden)

Junguito Bonnet Roberto

1996-06-01

Full Text Available This article describes the origin and evolution of the central banks of Argentina, Brazil, Chile, Colombia, Mexico, and Venezuela, and analyzes their respective institutional structures. It also studies the contribution of the central bank to stabilization and the problems for maintaining this independence into the future.Este artículo describe el origen y la evolución de los Bancos Centrales de Argentina, Brasil, Chile, Colombia, México y Venezuela, y analiza sus respectivas estructruras institucionales. También estudia la contribución de la banca central a la estabilización y los problemas para que esta independencia se mantenga en el futuro.

A Mesoamerican origin of cherimoya (Annona cherimola Mill.): Implications for the conservation of plant genetic resources.

Science.gov (United States)

Larranaga, N; Albertazzi, F J; Fontecha, G; Palmieri, M; Rainer, H; van Zonneveld, M; Hormaza, J I

2017-08-01

Knowledge on the structure and distribution of genetic diversity is a key aspect to plan and execute an efficient conservation and utilization of the genetic resources of any crop as well as for determining historical demographic inferences. In this work, a large data set of 1,765 accessions of cherimoya (Annona cherimola Mill, Annonaceae), an underutilized fruit tree crop native to the Neotropics and used as a food source by pre-Columbian cultures, was collected from six different countries across the American continent and amplified with nine highly informative microsatellite markers. The structure analyses, fine representation of the genetic diversity and an ABC approach suggest a Mesoamerican origin of the crop, contrary to previous reports, with clear implications for the dispersion of plant germplasm between Central and South America in pre-Columbian times. These results together with the potential distribution of the species in a climatic change context using two different climate models provide new insights for the history and conservation of extant genetic resources of cherimoya that can be applied to other currently underutilized woody perennial crops. © 2017 John Wiley & Sons Ltd.

Assessing genetic diversity of perennial ryegrass ( Lolium perenne L ...

African Journals Online (AJOL)

In this study, inter-simple sequence repeat (ISSR) markers were used to compare genetic diversity between commercial cultivars and natural germplasm which were obtained from Europe, Africa, Asia, and North America. There was a relatively high genetic variation in the whole collection judged by the polymorphism rate ...

Clinical Application of Epilepsy Genetics in Africa: Is Now the Time?

Directory of Open Access Journals (Sweden)

Alina I. Esterhuizen

2018-05-01

Full Text Available Over 80% of people with epilepsy live in low- to middle-income countries where epilepsy is often undiagnosed and untreated due to limited resources and poor infrastructure. In Africa, the burden of epilepsy is exacerbated by increased risk factors such as central nervous system infections, perinatal insults, and traumatic brain injury. Despite the high incidence of these etiologies, the cause of epilepsy in over 60% of African children is unknown, suggesting a possible genetic origin. Large-scale genetic and genomic research in Europe and North America has revealed new genes and variants underlying disease in a range of epilepsy phenotypes. The relevance of this knowledge to patient care is especially evident among infants with early-onset epilepsies, where early genetic testing can confirm the diagnosis and direct treatment, potentially improving prognosis and quality of life. In Africa, however, genetic epilepsies are among the most under-investigated neurological disorders, and little knowledge currently exists on the genetics of epilepsy among African patients. The increased diversity on the continent may yield unique, important epilepsy-associated genotypes, currently absent from the North American or European diagnostic testing protocols. In this review, we propose that there is strong justification for developing the capacity to offer genetic testing for children with epilepsy in Africa, informed mostly by the existing counseling and interventional needs. Initial simple protocols involving well-recognized epilepsy genes will not only help patients but will give rise to further clinically relevant research, thus increasing knowledge and capacity.

Mutations in BRCA1, BRCA2 and other breast and ovarian cancer susceptibility genes in Central and South American populations.

Science.gov (United States)

Jara, Lilian; Morales, Sebastian; de Mayo, Tomas; Gonzalez-Hormazabal, Patricio; Carrasco, Valentina; Godoy, Raul

2017-10-06

Breast cancer (BC) is the most common malignancy among women worldwide. A major advance in the understanding of the genetic etiology of BC was the discovery of BRCA1 and BRCA2 (BRCA1/2) genes, which are considered high-penetrance BC genes. In non-carriers of BRCA1/2 mutations, disease susceptibility may be explained of a small number of mutations in BRCA1/2 and a much higher proportion of mutations in ethnicity-specific moderate- and/or low-penetrance genes. In Central and South American populations, studied have focused on analyzing the distribution and prevalence of BRCA1/2 mutations and other susceptibility genes that are scarce in Latin America as compared to North America, Europe, Australia, and Israel. Thus, the aim of this review is to present the current state of knowledge regarding pathogenic BRCA variants and other BC susceptibility genes. We conducted a comprehensive review of 47 studies from 12 countries in Central and South America published between 2002 and 2017 reporting the prevalence and/or spectrum of mutations and pathogenic variants in BRCA1/2 and other BC susceptibility genes. The studies on BRCA1/2 mutations screened a total of 5956 individuals, and studies on susceptibility genes analyzed a combined sample size of 11,578 individuals. To date, a total of 190 different BRCA1/2 pathogenic mutations in Central and South American populations have been reported in the literature. Pathogenic mutations or variants that increase BC risk have been reported in the following genes or genomic regions: ATM, BARD1, CHECK2, FGFR2, GSTM1, MAP3K1, MTHFR, PALB2, RAD51, TOX3, TP53, XRCC1, and 2q35.

Genetic and environmental influences on height from infancy to early adulthood

DEFF Research Database (Denmark)

Jelenkovic, Aline; Sund, Reijo; Hur, Yoon-Mi

2016-01-01

Height variation is known to be determined by both genetic and environmental factors, but a systematic description of how their influences differ by sex, age and global regions is lacking. We conducted an individual-based pooled analysis of 45 twin cohorts from 20 countries, including 180......,520 paired measurements at ages 1-19 years. The proportion of height variation explained by shared environmental factors was greatest in early childhood, but these effects remained present until early adulthood. Accordingly, the relative genetic contribution increased with age and was greatest in adolescence...... (up to 0.83 in boys and 0.76 in girls). Comparing geographic-cultural regions (Europe, North-America and Australia, and East-Asia), genetic variance was greatest in North-America and Australia and lowest in East-Asia, but the relative proportion of genetic variation was roughly similar across...

Population structure of Han nationality in Central-Southern China.

Science.gov (United States)

Liu, Qiu-Ling; Chen, Ye-Fei; He, Xin; Shi, Yan-Wei; Wu, Wei-Wei; Zhao, Hu; Lu, De-Jian

2017-07-01

Knowledge of population structure is very important for forensic genetics. However, the population substructure in Central-Southern China Han nationality has still not been fully described. In this study, we investigated the genetic diversity of 15 forensic autosomal STR loci from 6879 individuals in 12 Han populations subdivided by administrative provinces in Central-Southern China. The statistical analysis of genetic variation showed that genetic differentiation among these populations was very small with a F st value of 0.0009. The Discriminant Analysis of Principal Components (DAPC) showed that there were no obvious population clusters in Central-Southern China Han population. In practice, the population structure effect in Central-Southern China Han population can be negligible in forensic identification and paternity testing. Copyright © 2017. Published by Elsevier B.V.

Hierarchical modeling of genome-wide Short Tandem Repeat (STR) markers infers native American prehistory.

Science.gov (United States)

Lewis, Cecil M

2010-02-01

This study examines a genome-wide dataset of 678 Short Tandem Repeat loci characterized in 444 individuals representing 29 Native American populations as well as the Tundra Netsi and Yakut populations from Siberia. Using these data, the study tests four current hypotheses regarding the hierarchical distribution of neutral genetic variation in native South American populations: (1) the western region of South America harbors more variation than the eastern region of South America, (2) Central American and western South American populations cluster exclusively, (3) populations speaking the Chibchan-Paezan and Equatorial-Tucanoan language stock emerge as a group within an otherwise South American clade, (4) Chibchan-Paezan populations in Central America emerge together at the tips of the Chibchan-Paezan cluster. This study finds that hierarchical models with the best fit place Central American populations, and populations speaking the Chibchan-Paezan language stock, at a basal position or separated from the South American group, which is more consistent with a serial founder effect into South America than that previously described. Western (Andean) South America is found to harbor similar levels of variation as eastern (Equatorial-Tucanoan and Ge-Pano-Carib) South America, which is inconsistent with an initial west coast migration into South America. Moreover, in all relevant models, the estimates of genetic diversity within geographic regions suggest a major bottleneck or founder effect occurring within the North American subcontinent, before the peopling of Central and South America. 2009 Wiley-Liss, Inc.

Population genetic history of Aristeus antennatus (Crustacea: Decapoda in the Western and Central Mediterranean Sea.

Directory of Open Access Journals (Sweden)

Annamaria Marra

Full Text Available Aristeus antennatus is an ecologically and economically important deep-water species in the Mediterranean Sea. In this study we investigated the genetic variability of A. antennatus sampled from 10 sampling stations in the Western and Central Mediterranean. By comparing our new samples with available data from the Western area, we aim to identify potential genetic stocks of A. antennatus and to reconstruct its historical demography in the Mediterranean. We analyzed two regions of mitochondrial DNA in 319 individuals, namely COI and 16S. We found two main results: i the genetic diversity values consistent with previous data within the Mediterranean and the absence of barriers to gene flow within the Mediterranean Sea; ii a constant long-term effective population size in almost all demes but a strong signature of population expansion in the pooled sample about 50,000 years B.P./ago. We propose two explanation for our results. The first is based on the ecology of A. antennatus. We suggest the existence of a complex meta-population structured into two layers: a deeper-dwelling stock, not affected by fishing, which preserves the pattern of historical demography; and genetically homogeneous demes inhabiting the fishing grounds. The larval dispersal, adult migration and continuous movements of individuals from "virgin" deeper grounds not affected by fishing to upper fishing areas support an effective 'rescue effect' contributing to the recovery of the exploited stocks and explain their genetic homogeneity throughout the Mediterranean Sea. The second is based on the reproduction model of this shrimp: the high variance in offspring production calls for a careful interpretation of the data observed under classical population genetics and Kingman's coalescent. In both cases, management policies for A. antennatus will therefore require careful evaluation of the meta-population dynamics of all stocks in the Mediterranean. In the future, it will be

The potential distribution of invading Helicoverpa armigera in North America: is it just a matter of time?

Directory of Open Access Journals (Sweden)

Darren J Kriticos

Full Text Available Helicoverpa armigera has recently invaded South and Central America, and appears to be spreading rapidly. We update a previously developed potential distribution model to highlight the global invasion threat, with emphasis on the risks to the United States. The continued range expansion of H. armigera in Central America is likely to change the invasion threat it poses to North America qualitatively, making natural dispersal from either the Caribbean islands or Mexico feasible. To characterise the threat posed by H. armigera, we collated the value of the major host crops in the United States growing within its modelled potential range, including that area where it could expand its range during favourable seasons. We found that the annual value of crops that would be exposed to H. armigera totalled approximately US$78 billion p.a., with US$843 million p.a. worth growing in climates that are optimal for the pest. Elsewhere, H. armigera has developed broad-spectrum pesticide resistance; meaning that if it invades the United States, protecting these crops from significant production impacts could be challenging. It may be cost-effective to undertake pre-emptive biosecurity activities such as slowing the spread of H. armigera throughout the Americas, improving the system for detecting H. armigera, and methods for rapid identification, especially distinguishing between H. armigera, H. zea and potential H. armigera x H. zea hybrids. Developing biological control programs, especially using inundative techniques with entomopathogens and parasitoids could slow the spread of H. armigera, and reduce selective pressure for pesticide resistance. The rapid spread of H. armigera through South America into Central America suggests that its spread into North America is a matter of time. The likely natural dispersal routes preclude aggressive incursion responses, emphasizing the value of preparatory communication with agricultural producers in areas suitable for

You Can't Unscramble an Egg: Population Genetic Structure of Oncorhynchus mykiss in the California Central Valley Inferred from Combined Microsatellite and Single Nucleotide Polymorphism Data

Directory of Open Access Journals (Sweden)

Devon E. Pearse

2015-12-01

Full Text Available doi: http://dx.doi.org/10.15447/sfews.2015v13iss4art3Steelhead/rainbow trout (Oncorhynchus mykiss are found in all of the major tributaries of the Sacramento and San Joaquin rivers, which flow through California’s Central Valley and enter the ocean through San Francisco Bay and the Golden Gate. This river system is heavily affected by water development, agriculture, and invasive species, and salmon and trout hatchery propagation has been occurring for over 100 years. We collected genotype data for 18 highly variable microsatellite loci and 95 single nucleotide polymorphisms (SNPs from more than 1,900 fish from Central Valley drainages to analyze genetic diversity, population structure, differentiation between populations above and below dams, and the relationship of Central Valley O. mykiss populations to coastal California steelhead. In addition, we evaluate introgression by both hatchery rainbow trout strains, which have primarily native Central Valley ancestry, and imported coastal steelhead stocks. In contrast to patterns typical of coastal steelhead, Central Valley O. mykiss above and below dams within the same tributary were not found to be each others’ closest relatives, and we found no relationship between genetic and geographic distance among below-barrier populations. While introgression by hatchery rainbow trout strains does not appear to be widespread among above-barrier populations, steelhead in the American River and some neighboring tributaries have been introgressed by coastal steelhead. Together, these results demonstrate that the ancestral population genetic structure that existed among Central Valley tributaries has been significantly altered in contemporary populations. Future conservation, restoration, and mitigation efforts should take this into account when working to meet recovery planning goals.

Obesity and hypertension in Latin America: Current perspectives.

Science.gov (United States)

Ruilope, L M; Nunes Filho, A C B; Nadruz, W; Rodríguez Rosales, F F; Verdejo-Paris, J

In the countries of Central America, South America and the Caribbean, there has been a dramatic rise in obesity, the metabolic syndrome, hypertension and other cardiovascular risk factors in the last few decades. Epidemiological evidence highlights a consistent correlation between obesity and hypertension, and the presence of obesity predisposes an individual to a greater risk of hypertension although the mechanisms remain unclear. Obesity and hypertension are two key drivers of the cardio-renal disease continuum, and patients with uncontrolled cardiovascular risk in their mid-life will likely have an increased risk of clinical cardiovascular and renal outcomes in old age. This article summarizes the current status for the prevalence and consequences of obesity and hypertension in Latin America, with the aim of initiating a call to action to all stakeholders for greater implementation of primary prevention strategies, particularly in the young. Copyright © 2018 SEH-LELHA. Publicado por Elsevier España, S.L.U. All rights reserved.

Spatial Genetic Structure of the Abundant and Widespread Peatmoss Sphagnum magellanicum Brid.

Directory of Open Access Journals (Sweden)

Magni Olsen Kyrkjeeide

Full Text Available Spore-producing organisms have small dispersal units enabling them to become widespread across continents. However, barriers to gene flow and cryptic speciation may exist. The common, haploid peatmoss Sphagnum magellanicum occurs in both the Northern and Southern hemisphere, and is commonly used as a model in studies of peatland ecology and peatmoss physiology. Even though it will likely act as a rich source in functional genomics studies in years to come, surprisingly little is known about levels of genetic variability and structuring in this species. Here, we assess for the first time how genetic variation in S. magellanicum is spatially structured across its full distribution range (Northern Hemisphere and South America. The morphologically similar species S. alaskense was included for comparison. In total, 195 plants were genotyped at 15 microsatellite loci. Sequences from two plastid loci (trnG and trnL were obtained from 30 samples. Our results show that S. alaskense and almost all plants of S. magellanicum in the northern Pacific area are diploids and share the same gene pool. Haploid plants occur in South America, Europe, eastern North America, western North America, and southern Asia, and five genetically differentiated groups with different distribution ranges were found. Our results indicate that S. magellanicum consists of several distinct genetic groups, seemingly with little or no gene flow among them. Noteworthy, the geographical separation of diploids and haploids is strikingly similar to patterns found within other haploid Sphagnum species spanning the Northern Hemisphere. Our results confirm a genetic division between the Beringian and the Atlantic that seems to be a general pattern in Sphagnum taxa. The pattern of strong genetic population structuring throughout the distribution range of morphologically similar plants need to be considered in future functional genomic studies of S. magellanicum.

Spatial Genetic Structure of the Abundant and Widespread Peatmoss Sphagnum magellanicum Brid.

Science.gov (United States)

Kyrkjeeide, Magni Olsen; Hassel, Kristian; Flatberg, Kjell Ivar; Shaw, A Jonathan; Yousefi, Narjes; Stenøien, Hans K

2016-01-01

Spore-producing organisms have small dispersal units enabling them to become widespread across continents. However, barriers to gene flow and cryptic speciation may exist. The common, haploid peatmoss Sphagnum magellanicum occurs in both the Northern and Southern hemisphere, and is commonly used as a model in studies of peatland ecology and peatmoss physiology. Even though it will likely act as a rich source in functional genomics studies in years to come, surprisingly little is known about levels of genetic variability and structuring in this species. Here, we assess for the first time how genetic variation in S. magellanicum is spatially structured across its full distribution range (Northern Hemisphere and South America). The morphologically similar species S. alaskense was included for comparison. In total, 195 plants were genotyped at 15 microsatellite loci. Sequences from two plastid loci (trnG and trnL) were obtained from 30 samples. Our results show that S. alaskense and almost all plants of S. magellanicum in the northern Pacific area are diploids and share the same gene pool. Haploid plants occur in South America, Europe, eastern North America, western North America, and southern Asia, and five genetically differentiated groups with different distribution ranges were found. Our results indicate that S. magellanicum consists of several distinct genetic groups, seemingly with little or no gene flow among them. Noteworthy, the geographical separation of diploids and haploids is strikingly similar to patterns found within other haploid Sphagnum species spanning the Northern Hemisphere. Our results confirm a genetic division between the Beringian and the Atlantic that seems to be a general pattern in Sphagnum taxa. The pattern of strong genetic population structuring throughout the distribution range of morphologically similar plants need to be considered in future functional genomic studies of S. magellanicum.

Cold-water fishes and climate change in North America

Science.gov (United States)

J. E. Williams; Daniel Isaak; J. Imhof; D. A. Hendrickson; J. R. McMillan

2015-01-01

Trout, salmon, grayling and whitefishes (Salmonidae) are among the most ecologically and economically important fishes. They also are among the most vulnerable to global warming, and increasing drought, floods, and wildfires. In North America, salmonids occur from central Mexico northward along coastal regions and mountainous interiors to the Arctic Plains. A...

Fatty Acid Diversity is Not Associated with Neutral Genetic Diversity in Native Populations of the Biodiesel Plant Jatropha curcas L.

Science.gov (United States)

Martínez-Díaz, Yesenia; González-Rodríguez, Antonio; Rico-Ponce, Héctor Rómulo; Rocha-Ramírez, Víctor; Ovando-Medina, Isidro; Espinosa-García, Francisco J

2017-01-01

Jatropha curcas L. (Euphorbiaceae) is a shrub native to Mexico and Central America, which produces seeds with a high oil content that can be converted to biodiesel. The genetic diversity of this plant has been widely studied, but it is not known whether the diversity of the seed oil chemical composition correlates with neutral genetic diversity. The total seed oil content, the diversity of profiles of fatty acids and phorbol esters were quantified, also, the genetic diversity obtained from simple sequence repeats was analyzed in native populations of J. curcas in Mexico. Using the fatty acids profiles, a discriminant analysis recognized three groups of individuals according to geographical origin. Bayesian assignment analysis revealed two genetic groups, while the genetic structure of the populations could not be explained by isolation-by-distance. Genetic and fatty acid profile data were not correlated based on Mantel test. Also, phorbol ester content and genetic diversity were not associated. Multiple linear regression analysis showed that total oil content was associated with altitude and seasonality of temperature. The content of unsaturated fatty acids was associated with altitude. Therefore, the cultivation planning of J. curcas should take into account chemical variation related to environmental factors. © 2017 Wiley-VHCA AG, Zurich, Switzerland.

Genetic diversity of giant clams (Tridacna spp.) and their associated Symbiodinium in the central Red Sea

KAUST Repository

Pappas, Melissa

2017-05-19

The biodiversity of the Red Sea remains relatively understudied, particularly for invertebrate taxa. Documenting present patterns of biodiversity is essential for better understanding Red Sea reef ecosystems and how these ecosystems may be impacted by stressors (such as fishing and climate change). Several species of giant clams (genus Tridacna) are reported from the Red Sea, although the majority of research effort has occurred in the Gulf of Aqaba. We investigated the genetic diversity (16S rDNA) of the Tridacna species found in the central Saudi Arabian Red Sea. We also investigated the genetic diversity (ITS rDNA) of symbiotic dinoflagellates Symbiodinium associated with these clams. Samples were collected from nine reefs on a cross-shelf gradient near Thuwal, Saudi Arabia. Two species, T. squamosa and T. maxima, were recorded, with the latter being the most abundant. Tridacna squamosina, a species recently reported in the northern Red Sea, was not found, suggesting that this species is not present or is very rare in our study region. All tridacnids sampled were found to harbor Symbiodinium grouped in Clade A, considered an opportunistic, heat-tolerant symbiont group in anemones and corals. The consistent association with Clade A Symbiodinium in central Red Sea tridacnids may reflect the consequence of adaptation to the relatively extreme conditions of the Red Sea. This study contributes to an ever-growing catalog of Red Sea biodiversity and serves as important baseline information for a region experiencing dynamic pressures.

Genetic diversity of giant clams (Tridacna spp.) and their associated Symbiodinium in the central Red Sea

KAUST Repository

Pappas, Melissa; He, Song; Hardenstine, Royale; Kanee, Hana; Berumen, Michael L.

2017-01-01

The biodiversity of the Red Sea remains relatively understudied, particularly for invertebrate taxa. Documenting present patterns of biodiversity is essential for better understanding Red Sea reef ecosystems and how these ecosystems may be impacted by stressors (such as fishing and climate change). Several species of giant clams (genus Tridacna) are reported from the Red Sea, although the majority of research effort has occurred in the Gulf of Aqaba. We investigated the genetic diversity (16S rDNA) of the Tridacna species found in the central Saudi Arabian Red Sea. We also investigated the genetic diversity (ITS rDNA) of symbiotic dinoflagellates Symbiodinium associated with these clams. Samples were collected from nine reefs on a cross-shelf gradient near Thuwal, Saudi Arabia. Two species, T. squamosa and T. maxima, were recorded, with the latter being the most abundant. Tridacna squamosina, a species recently reported in the northern Red Sea, was not found, suggesting that this species is not present or is very rare in our study region. All tridacnids sampled were found to harbor Symbiodinium grouped in Clade A, considered an opportunistic, heat-tolerant symbiont group in anemones and corals. The consistent association with Clade A Symbiodinium in central Red Sea tridacnids may reflect the consequence of adaptation to the relatively extreme conditions of the Red Sea. This study contributes to an ever-growing catalog of Red Sea biodiversity and serves as important baseline information for a region experiencing dynamic pressures.

Geographic origins and population genetics of bats killed at wind-energy facilities.

Science.gov (United States)

Pylant, Cortney L; Nelson, David M; Fitzpatrick, Matthew C; Gates, J Edward; Keller, Stephen R

2016-07-01

An unanticipated impact of wind-energy development has been large-scale mortality of insectivorous bats. In eastern North America, where mortality rates are among the highest in the world, the hoary bat (Lasiurus cinereus) and the eastern red bat (L. borealis) comprise the majority of turbine-associated bat mortality. Both species are migratory tree bats with widespread distributions; however, little is known regarding the geographic origins of bats killed at wind-energy facilities or the diversity and population structure of affected species. We addressed these unknowns by measuring stable hydrogen isotope ratios (δ 2 H) and conducting population genetic analyses of bats killed at wind-energy facilities in the central Appalachian Mountains (USA) to determine the summering origins, effective size, structure, and temporal stability of populations. Our results indicate that ~1% of hoary bat mortalities and ~57% of red bat mortalities derive from non-local sources, with no relationship between the proportion of non-local bats and sex, location of mortality, or month of mortality. Additionally, our data indicate that hoary bats in our sample consist of an unstructured population with a small effective size (N e ) and either a stable or declining history. Red bats also showed no evidence of population genetic structure, but in contrast to hoary bats, the diversity contained in our red bat samples is consistent with a much larger N e that reflects a demographic expansion after a bottleneck. These results suggest that the impacts of mortality associated with intensive wind-energy development may affect bat species dissimilarly, with red bats potentially better able to absorb sustained mortality than hoary bats because of their larger N e . Our results provide important baseline data and also illustrate the utility of stable isotopes and population genetics for monitoring bat populations affected by wind-energy development. © 2016 by the Ecological Society of America.

A 1200-Year Record of Rapid Climate Changes Across the Tropical Americas Identified from Lake Sediments (Invited)

Science.gov (United States)

Abbott, M.; Rodbell, D. T.; Stansell, N.; Bird, B. W.; Vuille, M.

2009-12-01

Well-dated, highly resolved lake sediment stratigraphies from similar catchments across the tropical Americas provide a means to investigate the timing, rate and direction of climate variability as well as providing a way to evaluate whether rapid changes occur synchronously in both hemispheres. This presentation focuses on the last 1500 years from three new high-resolution stable isotope records including Yuraicocha (12°32'S, 75°29'W), Pumacocha (10°41'S, 76° 3'36W), and Gancho (8°27'N, 80°51'W). These lakes are all sensitive to changes in P/E and the sediment records respond at subdecadal timescales. Additionally, the results from these sites are compared with lake level records from Titicaca (16°14'S, 68°37'W) and Blanca (8°19'N, 71°46'W) as well as other lake core and speleothem records from the region. The results show that in general conditions are dry across South America from ~800 AD until ~1300 AD with wetter conditions in Central America and the Caribbean. This pattern of dry conditions in tropical South America and wet conditions in the north reverses after ~1300 when conditions become wetter in South America, and drier in Central America and the Carrabin.

Climatic change on the Gulf of Fonseca (Central America) using two-step statistical downscaling of CMIP5 model outputs

Science.gov (United States)

Ribalaygua, Jaime; Gaitán, Emma; Pórtoles, Javier; Monjo, Robert

2018-05-01

A two-step statistical downscaling method has been reviewed and adapted to simulate twenty-first-century climate projections for the Gulf of Fonseca (Central America, Pacific Coast) using Coupled Model Intercomparison Project (CMIP5) climate models. The downscaling methodology is adjusted after looking for good predictor fields for this area (where the geostrophic approximation fails and the real wind fields are the most applicable). The method's performance for daily precipitation and maximum and minimum temperature is analysed and revealed suitable results for all variables. For instance, the method is able to simulate the characteristic cycle of the wet season for this area, which includes a mid-summer drought between two peaks. Future projections show a gradual temperature increase throughout the twenty-first century and a change in the features of the wet season (the first peak and mid-summer rainfall being reduced relative to the second peak, earlier onset of the wet season and a broader second peak).

Genetic composition and connectivity of the Antillean manatee (Trichechus manatus manatus) in Panama

Science.gov (United States)

Díaz-Ferguson, Edgardo; Hunter, Margaret; Guzmán, Héctor M.

2017-01-01

Genetic diversity and haplotype composition of the West Indian manatee (Trichechus manatus) population from the San San Pond Sak wetland in Bocas del Toro, Panama was studied using a segment of mitochondrial DNA (D’loop). No genetic information has been published to date for Panamanian populations. Due to the secretive behavior and small population size of the species in the area, DNA extraction was conducted from opportunistically collected fecal (N=20), carcass tissue (N=4) and bone (N=4) samples. However, after DNA processing only 10 samples provided good quality DNA for sequencing (3 fecal, 4 tissue and 3 bone samples). We found three haplotypes in total; two of these haplotypes are reported for the first time, J02 (N=3) and J03 (N=4), and one J01 was previously published (N=3). Genetic diversity showed similar values to previous studies conducted in other Caribbean regions with moderate values of nucleotide diversity (π= 0.00152) and haplotipic diversity (Hd= 0.57). Connectivity assessment was based on sequence similarity, genetic distance and genetic differentiation between San San population and other manatee populations previously studied. The J01 haplotype found in the Panamanian population is shared with populations in the Caribbean mainland and the Gulf of Mexico showing a reduced differentiation corroborated with Fst value between HSSPS and this region of 0.0094. In contrast, comparisons between our sequences and populations in the Eastern Caribbean (South American populations) and North Western Caribbean showed fewer similarities (Fst =0.049 and 0.058, respectively). These results corroborate previous phylogeographic patterns already established for manatee populations and situate Panamanian populations into the Belize and Mexico cluster. In addition, these findings will be a baseline for future studies and comparisons with manatees in other areas of Panama and Central America. These results should be considered to inform management decisions

Radical, reformist and aborted liberalism: origins of national regimes in Central America Liberalismo radical, reformista y frustrado: orígenes de los regímenes nacionales en América central

Directory of Open Access Journals (Sweden)

James MAHONEY

2011-06-01

Full Text Available During the twentieth century, the countries of Central America were characterized by remarkably different political regimes: military-authoritarianism in Guatemala and El Salvador, progressive democracy in Costa Rica and traditional-authoritarianism in Honduras and Nicaragua. This article explains these contrasting regime outcomes by exploring the agrarian and state-building reforms pursued by political leaders during the nineteenth– and early twentieth century liberal reform period. Based on differences in the transformation of state and class structures, three types of liberalism are identified: radical liberalism in Guatemala and El Salvador, reformist liberalism in Costa Rica and aborted liberalism in Honduras and Nicaragua. It is argued that these types of liberalism set the Central American countries on contrasting paths of political development, culminating in diverse regime outcomes.Durante el siglo XX, los países de América Central se caracterizaron por tener regímenes políticos muy diferentes: el autoritarismo militar en Guatemala y El Salvador; la democracia progresista en Costa Rica y el autoritarismo tradicional en Honduras y Nicaragua. Este artículo explica los resultados de estos distintos regímenes mediante la exploración de las reformas agrarias y de la construcción del Estado llevadas a cabo por los líderes políticos durante el siglo XIX y principios del periodo de reformas liberales del siglo XX. Basándose en las diferencias de la transformación del Estado y de las estructuras de clases, se pueden identificar tres tipos de liberalismo: liberalismo radical en Guatemala y El Salvador; liberalismo reformista en Costa Rica y liberalismo frustrado en Honduras y Nicaragua. Se argumenta que estos tipos de liberalismo condujeron a los países de América Central a caminos contrarios al desarrollo político, culminando así en regímenes con resultados diversos.

Inferences of population structure and demographic history for Taxodium distichum, a coniferous tree in North America, based on amplicon sequencing analysis.

Science.gov (United States)

Ikezaki, Yuka; Suyama, Yoshihisa; Middleton, Beth A; Tsumura, Yoshihiko; Teshima, Kousuke; Tachida, Hidenori; Kusumi, Junko

2016-11-01

Studies of natural genetic variation can elucidate the genetic basis of phenotypic variation and the past population structure of species. Our study species, Taxodium distichum, is a unique conifer that inhabits the flood plains and swamps of North America. Morphological and ecological differences in two varieties, T. distichum var. distichum (bald cypress) and T. distichum var. imbricarium (pond cypress), are well known, but little is known about the level of genetic differentiation between the varieties and the demographic history of local populations. We analyzed nucleotide polymorphisms at 47 nuclear loci from 96 individuals collected from the Mississippi River Alluvial Valley (MRAV), and Gulf Coastal populations in Texas, Louisiana, and Florida using high-throughput DNA sequencing. Standard population genetic statistics were calculated, and demographic parameters were estimated using a composite-likelihood approach. Taxodium distichum in North America can be divided into at least three genetic groups, bald cypress in the MRAV and Texas, bald cypress in Florida, and pond cypress in Florida. The levels of genetic differentiation among the groups were low but significant. Several loci showed the signatures of positive selection, which might be responsible for local adaptation or varietal differentiation. Bald cypress was genetically differentiated into two geographical groups, and the boundary was located between the MRAV and Florida. This differentiation could be explained by population expansion from east to west. Despite the overlap of the two varieties' ranges, they were genetically differentiated in Florida. The estimated demographic parameters suggested that pond cypress split from bald cypress during the late Miocene. © 2016 Botanical Society of America.

Checklist of fossil decapod crustaceans from tropical America. Part I: Anomura and Brachyura

Directory of Open Access Journals (Sweden)

Javier Luque

2017-10-01

Full Text Available Abstract Our knowledge of fossil crustaceans from the tropics has increased considerably during recent decades, thanks to novel findings and the re-examination of museum specimens. However, several previous records have been misidentified, numerous museum specimens have never been reported, and many new discoveries are yet to be published. Here, we present a detailed, up-to-date, and revised checklist for every marine, terrestrial, or freshwater fossil decapod crustacean occurrence from tropical America known to us, including their age, geographic occurrences, and related literature. We recognize the occurrence of at least 32 superfamilies, 69 families, 190 genera, and 415 species of brachyurans (‘true’ crabs, and anomurans (‘false’ crabs, hermit crabs, squat lobsters, and allies, several of them previously unknown. The checklist comprises records from three main geographic regions: 1 northern South America (Bolivia, Brazil, Chile, Colombia, Ecuador, Peru, Venezuela; 2 Central America and southern North America (Belize, Costa Rica, Honduras, Panama, Mexico, southern and central Florida; and 3 the Caribbean Islands + Bermuda (Anguilla, Antigua, Aruba, Bahamas, Barbados, Bermuda, Bonaire, Cuba, Curaçao, Dominican Republic, The Grenadines, Haiti, Jamaica, Puerto Rico, Saint Bartélemy, Saint Martin, Trinidad. Previous findings, new occurrences, and the revised systematic placement for several problematic/misidentified records, indicate that the fossil record of anomurans and brachyurans in tropical America is more diverse than previously envisioned, with a considerable degree of endemism at the genus- and species-levels.

Population genetic structure of a common host predicts the spread of white-nose syndrome, an emerging infectious disease in bats.

Science.gov (United States)

Wilder, Aryn P; Kunz, Thomas H; Sorenson, Michael D

2015-11-01

Landscape complexity influences patterns of animal dispersal, which in turn may affect both gene flow and the spread of pathogens. White-nose syndrome (WNS) is an introduced fungal disease that has spread rapidly throughout eastern North America, causing massive mortality in bat populations. We tested for a relationship between the population genetic structure of the most common host, the little brown myotis (Myotis lucifugus), and the geographic spread of WNS to date by evaluating logistic regression models of WNS risk among hibernating colonies in eastern North America. We hypothesized that risk of WNS to susceptible host colonies should increase with both geographic proximity and genetic similarity, reflecting historical connectivity, to infected colonies. Consistent with this hypothesis, inclusion of genetic distance between infected and susceptible colonies significantly improved models of disease spread, capturing heterogeneity in the spatial expansion of WNS despite low levels of genetic differentiation among eastern populations. Expanding our genetic analysis to the continental range of little brown myotis reveals strongly contrasting patterns of population structure between eastern and western North America. Genetic structure increases markedly moving westward into the northern Great Plains, beyond the current distribution of WNS. In western North America, genetic differentiation of geographically proximate populations often exceeds levels observed across the entire eastern region, suggesting infrequent and/or locally restricted dispersal, and thus relatively limited opportunities for pathogen introduction in western North America. Taken together, our analyses suggest a possibly slower future rate of spread of the WNS pathogen, at least as mediated by little brown myotis. © 2015 John Wiley & Sons Ltd.

Atmospheric circulation associated with extreme generalized frosts persistence in central-southern South America

Energy Technology Data Exchange (ETDEWEB)

Mueller, Gabriela V. [Centro de Investigaciones Cientificas y Transferencia de Tecnologia a la Produccion, Diamante (CICYTTTP-CONICET), Diamante, Entre Rios (Argentina); Berri, Guillermo J. [Servicio Meteorologico Nacional - CONICET, Buenos Aires (Argentina)

2012-03-15

Generalized frosts (GF) in central-southern South America have a strong impact due to their spatial extension, and they are especially important when they become persistent. This paper aims at identifying the atmospheric circulation features that determine the extreme GF persistence, i.e. very persistent and without persistence, and the differences between them, during the 1961-1990 winters. Since the GF without persistence group outnumbers the other one, two subgroups are composed with events selected from winters with maximum and minimum frequency of GF occurrence, respectively. Additionally, the individual event of July 1988 within the very persistent GF group is analyzed due to its exceptional persistence. GF persistence is mainly conditioned by two large-scale dynamic factors. One is the Rossby wave train propagation across the Pacific Ocean, and the other one is the location with respect to the continent and the magnitude of the confluence in the jet entrance region in subtropical latitudes. A predominantly meridional Rossby wave train propagation with a confluence region to the west of the continent prior to the event favors GF with intermediate (null) persistence depending on the greater (lesser) jet acceleration. This is conditioned by the magnitude of the confluence, which, in turn, depends on the disposition of the wave train propagation pattern. Instead, an essentially zonal propagation with a confluence region to the east of the continent favors the GF persistence for several days, yet if there is no confluence the event does not persist. The greatest persistence of an event combines the confluence/diffluence of the jet entrance/exit region, which depends on the disposition with respect to the continent of the zonally propagating Rossby wave trains. (orig.)

The Africa South America Intercontinental Teleconnection.

Science.gov (United States)

Cook, K. H.; Hsieh, J.-S.; Hagos, S. M.

2004-07-01

The influence of heating over Africa on the South American precipitation climatology, and the influence of South America on Africa, is examined through the application of GCM simulations with idealized boundary conditions and perpetual solstice (January and July) conditions.The presence of Africa is associated with a pronounced (up to 4 mm day-1) decrease in precipitation in Brazil's Nordeste region during austral summer. Low-level moisture divergence and dry-air advection associated with the downbranch of a Walker circulation induced by heating over southern Africa is amplified over the Nordeste due to the response of the land surface. The response is much smaller during austral winter due to differences in the heat source over Africa and a reduced sensitivity in the surface heat balance over tropical South America. Forcing from South America in January shifts the position of the South Indian convergence zone (SICZ) to the southwest over southern Africa in association with the formation of the South Atlantic convergence zone (SACZ). In July, a Rossby wave train generated over South America induces a response in the surface temperature of Africa that leads to stronger precipitation in central and western Africa.This study suggests a zonal mode of variability for South American and African circulation and precipitation fields. The resulting perturbations depend as much on land surface atmosphere interactions as on the direct forcing from the adjacent continent, and the mechanisms are highly nonlinear.

Is the Supercourse useful for Latin America?

Directory of Open Access Journals (Sweden)

Nicolas Padilla-Raygoza

2013-02-01

Full Text Available BACKGROUND: The success of the Supercourse showed that the effort was needed in Latin America. But would a Spanish language version be better for the region? METHODS: Google Analytics was used to determine website usage. A custom evaluation form was created to get user feedback on the usefulness of both the English language and Spanish language Supercouse lectures. RESULTS: Over a year's span from June 2009 to June 2010 there were 257,403 unique visits and 448,939 page views. The overall average rating of lectures was 4.87 with the Spanish language lectures getting even higher ratings. CONCLUSION: Supercourse lectures in Spanish were a great success in Latin America. This success shows the need for this information and similar success could be found in Central Asia.

Agricultural drought assessment using remotely sensed data in Central America

Science.gov (United States)

Nguyen, S. T.; Chen, C. F.; Chen, C. R.

2017-12-01

Central America is one of the world's regions most vulnerable to negative effects of agricultural drought due to impacts of climate change. Famers in the region have been confronting risks of crop damages and production losses due to intense droughts throughout the growing seasons. Drought information is thus deemed vital for policymakers to assess their crop management strategies in tackling issues of food insecurity in the region. This study aimed to delineate drought-prone areas associated with cropped areas from eight-day MODIS data in 2016 using the commonly used temperature dryness vegetation index (TVDI), calculated based on the land surface temperature (LST) and enhanced vegetation index (EVI) data. The advantages of MODIS data for agricultural drought monitoring at a national/regional scale are that it has the spatial resolution (500 m-1 km) and relatively high temporal resolution of eight days, but the data are often contaminated by clouds. Detecting and reconstructing the data under cloud-affected areas are generally a challenging task without any robust methods up to date. In this study, we reconstructed the eight-day MODIS EVI and LST data for agricultural drought assessment using machine-learning approaches. The reconstructed data were then used for drought assessment. The TVDI results verified with the soil moisture active passive (SMAP) data showed that the correlation coefficient values (r) obtained for the apante season (December-March) were between -0.4 to -0.8, while the values for the primera season (April-August) and postrera season (September-November) were in ranges of 0 to -0.6 and -0.2 to -0.7, respectively. The larger area of very dry soil moisture was generally observed during the dry season (December-April) and declined in the rainy season (May-November). The cropping areas affected by severe and moderate droughts observed for the primera season were respectively 11,846 km2 and 60,557 km2, while the values for the postera season were 14

Population genetics of Glossina palpalis palpalis from central African sleeping sickness foci

Directory of Open Access Journals (Sweden)

Solano Philippe

2011-07-01

Full Text Available Abstract Background Glossina palpalis palpalis (Diptera: Glossinidae is widespread in west Africa, and is the main vector of sleeping sickness in Cameroon as well as in the Bas Congo Province of the Democratic Republic of Congo. However, little is known on the structure of its populations. We investigated G. p. palpalis population genetic structure in five sleeping sickness foci (four in Cameroon, one in Democratic Republic of Congo using eight microsatellite DNA markers. Results A strong isolation by distance explains most of the population structure observed in our sampling sites of Cameroon and DRC. The populations here are composed of panmictic subpopulations occupying fairly wide zones with a very strong isolation by distance. Effective population sizes are probably between 20 and 300 individuals and if we assume densities between 120 and 2000 individuals per km2, dispersal distance between reproducing adults and their parents extends between 60 and 300 meters. Conclusions This first investigation of population genetic structure of G. p. palpalis in Central Africa has evidenced random mating subpopulations over fairly large areas and is thus at variance with that found in West African populations of G. p. palpalis. This study brings new information on the isolation by distance at a macrogeographic scale which in turn brings useful information on how to organise regional tsetse control. Future investigations should be directed at temporal sampling to have more accurate measures of demographic parameters in order to help vector control decision.

Admixture in Latin America: Geographic Structure, Phenotypic Diversity and Self-Perception of Ancestry Based on 7,342 Individuals

Science.gov (United States)

Ruiz-Linares, Andrés; Adhikari, Kaustubh; Acuña-Alonzo, Victor; Quinto-Sanchez, Mirsha; Jaramillo, Claudia; Arias, William; Fuentes, Macarena; Pizarro, María; Everardo, Paola; de Avila, Francisco; Gómez-Valdés, Jorge; León-Mimila, Paola; Hunemeier, Tábita; Ramallo, Virginia; Silva de Cerqueira, Caio C.; Burley, Mari-Wyn; Konca, Esra; de Oliveira, Marcelo Zagonel; Veronez, Mauricio Roberto; Rubio-Codina, Marta; Attanasio, Orazio; Gibbon, Sahra; Ray, Nicolas; Gallo, Carla; Poletti, Giovanni; Rosique, Javier; Schuler-Faccini, Lavinia; Salzano, Francisco M.; Bortolini, Maria-Cátira; Canizales-Quinteros, Samuel; Rothhammer, Francisco; Bedoya, Gabriel; Balding, David; Gonzalez-José, Rolando

2014-01-01

The current genetic makeup of Latin America has been shaped by a history of extensive admixture between Africans, Europeans and Native Americans, a process taking place within the context of extensive geographic and social stratification. We estimated individual ancestry proportions in a sample of 7,342 subjects ascertained in five countries (Brazil, Chile, Colombia, México and Perú). These individuals were also characterized for a range of physical appearance traits and for self-perception of ancestry. The geographic distribution of admixture proportions in this sample reveals extensive population structure, illustrating the continuing impact of demographic history on the genetic diversity of Latin America. Significant ancestry effects were detected for most phenotypes studied. However, ancestry generally explains only a modest proportion of total phenotypic variation. Genetically estimated and self-perceived ancestry correlate significantly, but certain physical attributes have a strong impact on self-perception and bias self-perception of ancestry relative to genetically estimated ancestry. PMID:25254375

Admixture in Latin America: geographic structure, phenotypic diversity and self-perception of ancestry based on 7,342 individuals.

Science.gov (United States)

Ruiz-Linares, Andrés; Adhikari, Kaustubh; Acuña-Alonzo, Victor; Quinto-Sanchez, Mirsha; Jaramillo, Claudia; Arias, William; Fuentes, Macarena; Pizarro, María; Everardo, Paola; de Avila, Francisco; Gómez-Valdés, Jorge; León-Mimila, Paola; Hunemeier, Tábita; Ramallo, Virginia; Silva de Cerqueira, Caio C; Burley, Mari-Wyn; Konca, Esra; de Oliveira, Marcelo Zagonel; Veronez, Mauricio Roberto; Rubio-Codina, Marta; Attanasio, Orazio; Gibbon, Sahra; Ray, Nicolas; Gallo, Carla; Poletti, Giovanni; Rosique, Javier; Schuler-Faccini, Lavinia; Salzano, Francisco M; Bortolini, Maria-Cátira; Canizales-Quinteros, Samuel; Rothhammer, Francisco; Bedoya, Gabriel; Balding, David; Gonzalez-José, Rolando

2014-09-01

The current genetic makeup of Latin America has been shaped by a history of extensive admixture between Africans, Europeans and Native Americans, a process taking place within the context of extensive geographic and social stratification. We estimated individual ancestry proportions in a sample of 7,342 subjects ascertained in five countries (Brazil, Chile, Colombia, México and Perú). These individuals were also characterized for a range of physical appearance traits and for self-perception of ancestry. The geographic distribution of admixture proportions in this sample reveals extensive population structure, illustrating the continuing impact of demographic history on the genetic diversity of Latin America. Significant ancestry effects were detected for most phenotypes studied. However, ancestry generally explains only a modest proportion of total phenotypic variation. Genetically estimated and self-perceived ancestry correlate significantly, but certain physical attributes have a strong impact on self-perception and bias self-perception of ancestry relative to genetically estimated ancestry.

Central America : Big Data in Action for Development

OpenAIRE

World Bank

2014-01-01

This report stemmed from a World Bank pilot activity to explore the potential of big data to address development challenges in Central American countries. As part of this activity we collected and analyzed a number of examples of leveraging big data for development. Because of the growing interest in this topic this report makes available to a broader audience those examples as well as the...

Elements for a Geopolitics of Infrastructure Megaprojects in Latin America and Colombia

Directory of Open Access Journals (Sweden)

Fabio Vladimir Sánchez Calderón

2008-01-01

Full Text Available This paper develops a critical approach to projects and initiatives of supranational physical connection through infrastructure improvement for transport and energy, regarding specifically their socio-spatial implications at the national and local levels. With this purpose, we examined how infrastructure projects in Colombia are linked to two sub-continental initiatives that seek to build a physical platform for the region: the Plan Puebla Panama (PPP for Central America (including Colombia, and the Initiative for Regional Integration of South America (IIRSA.

Use of linkage mapping and centrality analysis across habitat gradients to conserve connectivity of gray wolf populations in western North America.

Science.gov (United States)

Carroll, Carlos; McRae, Brad H; Brookes, Allen

2012-02-01

. Centrality analysis is relevant to conservation and landscape genetics at a range of spatial extents, but it may be most broadly applicable within single- and multispecies planning efforts to conserve regional habitat connectivity. ©2011 Society for Conservation Biology.

Central American Flying Weather

Science.gov (United States)

1985-12-01

CEILING; VISIBILITY; WIND, PRECIPITATIDNc’--." HAZE, SMOKE, TEMPORALE ; MOUNTAIN WAVE; MILITARY METEOROLOGY. 4k- / ’A. bstract; Asummary of~ing weather...1 The " Temporale " ....................................1 Mountain Waves ......................I...............1 Severe Thunderstorms...charts. The for any part of Central America lies in having: Tactical Pilota.e Chart series , produced by the Df -.nse Mapping Agency, is * A good, basic

Hydro, wind and solar power as a base for a 100% renewable energy supply for South and Central America.

Directory of Open Access Journals (Sweden)

Larissa de Souza Noel Simas Barbosa

Full Text Available Power systems for South and Central America based on 100% renewable energy (RE in the year 2030 were calculated for the first time using an hourly resolved energy model. The region was subdivided into 15 sub-regions. Four different scenarios were considered: three according to different high voltage direct current (HVDC transmission grid development levels (region, country, area-wide and one integrated scenario that considers water desalination and industrial gas demand supplied by synthetic natural gas via power-to-gas (PtG. RE is not only able to cover 1813 TWh of estimated electricity demand of the area in 2030 but also able to generate the electricity needed to fulfil 3.9 billion m3 of water desalination and 640 TWhLHV of synthetic natural gas demand. Existing hydro dams can be used as virtual batteries for solar and wind electricity storage, diminishing the role of storage technologies. The results for total levelized cost of electricity (LCOE are decreased from 62 €/MWh for a highly decentralized to 56 €/MWh for a highly centralized grid scenario (currency value of the year 2015. For the integrated scenario, the levelized cost of gas (LCOG and the levelized cost of water (LCOW are 95 €/MWhLHV and 0.91 €/m3, respectively. A reduction of 8% in total cost and 5% in electricity generation was achieved when integrating desalination and power-to-gas into the system.

Hydro, wind and solar power as a base for a 100% renewable energy supply for South and Central America.

Science.gov (United States)

Barbosa, Larissa de Souza Noel Simas; Bogdanov, Dmitrii; Vainikka, Pasi; Breyer, Christian

2017-01-01

Power systems for South and Central America based on 100% renewable energy (RE) in the year 2030 were calculated for the first time using an hourly resolved energy model. The region was subdivided into 15 sub-regions. Four different scenarios were considered: three according to different high voltage direct current (HVDC) transmission grid development levels (region, country, area-wide) and one integrated scenario that considers water desalination and industrial gas demand supplied by synthetic natural gas via power-to-gas (PtG). RE is not only able to cover 1813 TWh of estimated electricity demand of the area in 2030 but also able to generate the electricity needed to fulfil 3.9 billion m3 of water desalination and 640 TWhLHV of synthetic natural gas demand. Existing hydro dams can be used as virtual batteries for solar and wind electricity storage, diminishing the role of storage technologies. The results for total levelized cost of electricity (LCOE) are decreased from 62 €/MWh for a highly decentralized to 56 €/MWh for a highly centralized grid scenario (currency value of the year 2015). For the integrated scenario, the levelized cost of gas (LCOG) and the levelized cost of water (LCOW) are 95 €/MWhLHV and 0.91 €/m3, respectively. A reduction of 8% in total cost and 5% in electricity generation was achieved when integrating desalination and power-to-gas into the system.

Elia Kazan's America America: A Message for America.

Science.gov (United States)

Molofsky, Merle

2018-06-01

Elia Kazan's 1963 film, America America is a tribute to the immigrant experience of his own forebears, and has relevance to the refugee crisis of today. In stark black and white cinematography, the film provides insight into the refugee-immigrant experience, personified in Stavros, a young man longing for freedom, obsessed with an idealized America. His hope and innocence cannot safeguard him. His memories of his happy childhood and loving family create idealizing transferences to a world of others who manipulate and betray him as he undertakes his quest. Eventually he too learns to manipulate and betray, unconsciously identifying with the aggressor. History will offer ethical challenges, the black and white cinematography mirroring the black and white perception of good and bad, the shades of grey evoking a maturation of understanding.

Pleistocene climatic oscillations rather than recent human disturbance influence genetic diversity in one of the world's highest treeline species.

Science.gov (United States)

Peng, Yanling; Lachmuth, Susanne; Gallegos, Silvia C; Kessler, Michael; Ramsay, Paul M; Renison, Daniel; Suarez, Ricardo; Hensen, Isabell

2015-10-01

Biological responses to climatic change usually leave imprints on the genetic diversity and structure of plants. Information on the current genetic diversity and structure of dominant tree species has facilitated our general understanding of phylogeographical patterns. Using amplified fragment length polymorphism (AFLPs), we compared genetic diversity and structure of 384 adults of P. tarapacana with those of 384 seedlings across 32 forest sites spanning a latitudinal gradient of 600 km occurring between 4100 m and 5000 m a.s.l. in Polylepis tarapacana (Rosaceae), one of the world's highest treeline species endemic to the central Andes. Moderate to high levels of genetic diversity and low genetic differentiation were detected in both adults and seedlings, with levels of genetic diversity and differentiation being almost identical. Four slightly genetically divergent clusters were identified that accorded to differing geographical regions. Genetic diversity decreased from south to north and with increasing precipitation for adults and seedlings, but there was no relationship to elevation. Our study shows that, unlike the case for other Andean treeline species, recent human activities have not affected the genetic structure of P. tarapacana, possibly because its inhospitable habitat is unsuitable for agriculture. The current genetic pattern of P. tarapacana points to a historically more widespread distribution at lower altitudes, which allowed considerable gene flow possibly during the glacial periods of the Pleistocene epoch, and also suggests that the northern Argentinean Andes may have served as a refugium for historical populations. © 2015 Botanical Society of America.

Characterization and efficacy determination of commercially available Central American H5N2 avian influenza vaccines for poultry.

Science.gov (United States)

Eggert, Dawn; Thomas, Colleen; Spackman, Erica; Pritchard, Nikki; Rojo, Francisco; Bublot, Michel; Swayne, David E

2010-06-23

A poultry vaccination program was implemented in Central America beginning in January 1995 to control both H5N2 low (LPAI) and high pathogenicity avian influenza. This study was conducted to identify seed strain composition and the efficacy of 10 commercially available H5 vaccines against challenge with H5N2 LPAI viruses isolated from Latin America in 2003. The original 1994 vaccine seed virus in commercial inactivated vaccines did not significantly reduce challenge virus shed titers. However, two seed strains of inactivated vaccines, genetically more closely related to the challenge virus, did significantly reduce titers of challenge virus shed from respiratory tract. In addition, a live recombinant fowlpox virus vaccine containing a more distantly related Eurasian lineage H5 gene insert significantly reduced respiratory shedding as compared to sham vaccinates. These results demonstrate the feasibility of identifying vaccine seed strains in commercial finished products for regulatory verification and the need for periodic challenge testing against current field strains in order to select efficacious vaccine seed strains. (c) 2010 Elsevier Ltd. All rights reserved.

Genetic diversity of the floury race of maize Avati Morotî from the Guaraní tribe in Paraguay

Energy Technology Data Exchange (ETDEWEB)

Orlando Noldin, O.; Revilla, P.; Ordás, B.

2016-11-01

Avati Morotî is a race of floury maize widely used by the Guarani people in South America, whose variability and potential value for breeding has been neglected so far. The objective of this research was to explore the genetic variability within the main Paraguayan race Avati Morotî. We studied the genetic variability available in the 20 accessions of Paraguayan Avati Morotî included in the South American core collection made by CIMMYT. Thirty individuals per accession were genotyped with 30 SSR (simple sequence repeat); we determined genetic diversity and made a cluster analysis in order to define genetic relationships among accessions. Mean of polymorphic loci (0.96), alleles per locus (3.57), alleles per polymorphic locus (3.65), expected (0.48) and observed (0.43) heterozygosity, and coefficient of consanguinity (0.12) revealed that Avati Morotî contains a genetic diversity comparable to the most variable maize races of maize. The cluster analysis classified the 20 populations in eight groups, five of them with a single accession, and a large group representing a central pool of germplasm. These results indicate that there is a large variability available in this race, and encourage the collection of more samples of Avati Morotî, particularly in marginal areas that were scarcely sampled. (Author)

Environment and development in Latin America: the politics of sustainability

International Nuclear Information System (INIS)

Goodman, David; Redclift, Michael

1991-01-01

The terms sustainability and sustainable development are used to refer to sustainable levels of both production and consumption taking environmental considerations into account. However, there are different interpretations of the terms, and the first chapter of this book considers these and looks at various aspects of sustainable development in Latin America. In this region sustainability has often been systematically devalued, missed altogether or simply lost. The remaining nine chapters of the book address debt, hunger, genetic resources, forestry management, acroecology and green issues of the Amazon. Costa Rica is the subject of one of the chapters and the environmental problems of Mexico City another. The chapter on nuclear energy and sustainability in Latin America is indexed separately. (UK)

Domestication and human demographic history in South America.

Science.gov (United States)

Perez, S Ivan; Postillone, María Bárbara; Rindel, Diego

2017-05-01

The early groups of hunter-gatherers who peopled South America faced significant ecological changes in their trophic niche for a relatively short period after the initial peopling. In particular, the incorporation of cultigens during the Holocene led to a wider trophic niche and probably to an increased carrying capacity of the environment. Here, we study the relationship between the incorporation of domestic resources during the Holocene and the demographic dynamics of human populations at a regional scale in South America. We employ mitochondrial DNA (mtDNA), radiocarbon data and Bayesian methods to estimate differences in population size, human occupation and explore the demographic changes of human populations in three regions (i.e., South-Central Andes, Northwest, and South Patagonia). We also use archaeological evidence to infer the main diet changes in these regions. The absolute population size during the later Late Holocene was fifteen times larger in the South-Central Andes than in Northwest Patagonia, and two times larger in the latter region than in South Patagonia. The South-Central Andes display the earlier and more abrupt population growth, beginning about 9000 years BP, whereas Northwest Patagonia exhibits a more slow growth, beginning about 7000-7500 years BP. South Patagonia represents a later and slower population increase. In this work we uncovered a well-supported pattern of the demographic change in the populations from South-Central Andes and Patagonia, obtained on the basis of different data and quantitative approaches, which suggests that the incorporation of domestic resources was paramount for the demographic expansion of these populations during the Holocene. © 2017 Wiley Periodicals, Inc.

Yellow Rust Epidemics Worldwide Were Caused by Pathogen Races from Divergent Genetic Lineages

DEFF Research Database (Denmark)

Ali, Sajid; Rodriguez Algaba, Julian; Thach, Tine

2017-01-01

population across geographical regions. The results emphasized the lack of predictability of emergence of new races with high epidemic potential, which stresses the need for additional investments in population biology and surveillance activities of pathogens on global food crops, and assessments of disease...... that these epidemics were often driven by races from few but highly divergent genetic lineages. PstS1 was predominant in North America; PstS2 in West Asia and North Africa; and both PstS1 and PstS2 in East Africa. PstS4 was prevalent in Northern Europe on triticale; PstS5 and PstS9 were prevalent in Central Asia......; whereas PstS6 was prevalent in epidemics in East Africa. PstS7, PstS8 and PstS10 represented three genetic lineages prevalent in Europe. Races from other lineages were in low frequencies. Virulence to Yr9 and Yr27 was common in epidemics in Africa and Asia, while virulence to Yr17 and Yr32 were prevalent...

Phylodynamic analysis of avian infectious bronchitis virus in South America.

Science.gov (United States)

Marandino, Ana; Pereda, Ariel; Tomás, Gonzalo; Hernández, Martín; Iraola, Gregorio; Craig, María Isabel; Hernández, Diego; Banda, Alejandro; Villegas, Pedro; Panzera, Yanina; Pérez, Ruben

2015-06-01

Infectious bronchitis virus (IBV) is a coronavirus of chickens that causes great economic losses to the global poultry industry. The present study focuses on South American IBVs and their genetic relationships with global strains. We obtained full-length sequences of the S1 coding region and N gene of IBV field isolates from Uruguay and Argentina, and performed Phylodynamic analysis to characterize the strains and estimate the time of the most recent common ancestor. We identified two major South American genotypes, which were here denoted South America I (SAI) and Asia/South America II (A/SAII). The SAI genotype is an exclusive South American lineage that emerged in the 1960s. The A/SAII genotype may have emerged in Asia in approximately 1995 before being introduced into South America. Both SAI and A/SAII genotype strains clearly differ from the Massachusetts strains that are included in the vaccine formulations being used in most South American countries. © 2015 The Authors.

Cold episodes in the Peruvian Central Andes: Composites, Types, and their Impacts over South America (1958-2014)

Science.gov (United States)

Sulca, J. C.; Vuille, M. F.; Roundy, P. E.; Trasmonte, G.; Silva, Y.; Takahashi, K.

2015-12-01

The Mantaro basin (MB) is located in the central Peruvian Andes. Occasionally, cold episodes are observed during austral summer (January-March), that strongly damage crops. However, little is known about the causes and impacts of such cold episodes. The main goal of this study is thus to characterize cold episodes in the MB and assess their large-scale circulation and teleconnections over South America (SA) during austral summer. To identify cold events in the MB daily minimum temperature (Tmin) for the period 1958-2014 from Huayao station, located within the MB was used. A cold episode is defined when daily minimum temperature drops below its 10-percentile for at least one day. Additionally, to study the sensitivity between physical mechanisms associated with cold episodes and temperature, cold episodes are classified in three groups: Weak cold episodes (7.5 ≤ Tmin ≤ 10 percentile), strong cold episodes (Tmin ≤ 2.5 percentile), but excluding the 9 coldest events (Tmin ≤ 0 ͦ C), henceforth referred to as extraordinary cold episodes. Several gridded reanalysis were used to characterize the large-scale circulation, cloud cover and rainfall over SA associated with these events. Weak and strong cold episodes in the MB are mainly associated with a weakening of the Bolivian High-Nordeste Low system by tropical-extratropical interactions. Both types of cold episodes are associated with westerly wind anomalies at mid- and upper-tropospheric levels aloft the Peruvian Central Andes, which inhibit the influx of humid air masses from the lowlands to the east and hence limit the development of cloud cover (e.g., positive OLR anomalies over MB). The resulting clear sky conditions cause nighttime temperatures to drop, leading to cold extremes below 10-percentile. Simultaneously, northeastern Brazil (NEB) registers negative OLR anomalies, strong convection and enhanced cloud cover because displacement of the South Atlantic Convergence Zone (SACZ) toward the northeast of

Tsunami hazard assessment in El Salvador, Central America, from seismic sources through flooding numerical models.

Science.gov (United States)

Álvarez-Gómez, J. A.; Aniel-Quiroga, Í.; Gutiérrez-Gutiérrez, O. Q.; Larreynaga, J.; González, M.; Castro, M.; Gavidia, F.; Aguirre-Ayerbe, I.; González-Riancho, P.; Carreño, E.

2013-11-01

El Salvador is the smallest and most densely populated country in Central America; its coast has an approximate length of 320 km, 29 municipalities and more than 700 000 inhabitants. In El Salvador there were 15 recorded tsunamis between 1859 and 2012, 3 of them causing damages and resulting in hundreds of victims. Hazard assessment is commonly based on propagation numerical models for earthquake-generated tsunamis and can be approached through both probabilistic and deterministic methods. A deterministic approximation has been applied in this study as it provides essential information for coastal planning and management. The objective of the research was twofold: on the one hand the characterization of the threat over the entire coast of El Salvador, and on the other the computation of flooding maps for the three main localities of the Salvadorian coast. For the latter we developed high-resolution flooding models. For the former, due to the extension of the coastal area, we computed maximum elevation maps, and from the elevation in the near shore we computed an estimation of the run-up and the flooded area using empirical relations. We have considered local sources located in the Middle America Trench, characterized seismotectonically, and distant sources in the rest of Pacific Basin, using historical and recent earthquakes and tsunamis. We used a hybrid finite differences-finite volumes numerical model in this work, based on the linear and non-linear shallow water equations, to simulate a total of 24 earthquake-generated tsunami scenarios. Our results show that at the western Salvadorian coast, run-up values higher than 5 m are common, while in the eastern area, approximately from La Libertad to the Gulf of Fonseca, the run-up values are lower. The more exposed areas to flooding are the lowlands in the Lempa River delta and the Barra de Santiago Western Plains. The results of the empirical approximation used for the whole country are similar to the results

Genetic response to metabolic fluctuations: correlation between central carbon metabolism and DNA replication in Escherichia coli

Directory of Open Access Journals (Sweden)

Szalewska-Pałasz Agnieszka

2011-03-01

Full Text Available Abstract Background Until now, the direct link between central carbon metabolism and DNA replication has been demonstrated only in Bacillus. subtilis. Therefore, we asked if this is a specific phenomenon, characteristic for this bacterium and perhaps for its close relatives, or a more general biological rule. Results We found that temperature-sensitivity of mutants in particular genes coding for replication proteins could be suppressed by deletions of certain genes coding for enzymes of the central carbon metabolism. Namely, the effects of dnaA46(ts mutation could be suppressed by dysfunction of pta or ackA, effects of dnaB(ts by dysfunction of pgi or pta, effects of dnaE486(ts by dysfunction of tktB, effects of dnaG(ts by dysfunction of gpmA, pta or ackA, and effects of dnaN159(ts by dysfunction of pta or ackA. The observed suppression effects were not caused by a decrease in bacterial growth rate. Conclusions The genetic correlation exists between central carbon metabolism and DNA replication in the model Gram-negative bacterium, E. coli. This link exists at the steps of initiation and elongation of DNA replication, indicating the important global correlation between metabolic status of the cell and the events leading to cell reproduction.

Emerging deforestation trends in tropical dry forests ecoregions of Mexico and Central America

Science.gov (United States)

Portillo, C. A.; Cao, G.; Smith, V.

2015-12-01

Neotropical dry forests (TDF) have experienced an unprecedented deforestation that is leading to the loss of tropical biodiversity at a rapid pace, but information on deforestation dynamics in TDF is scarce. In this study, we present a sub-continental and national level assessment of TDF loss patterns in Mexico and Central America at high spatial and temporal resolution using remote sensing and GIS technologies. We used the Global Forest Change (GFC) dataset published by Hansen et al. (2013) which shows results from time-series analysis of Landsat images in characterizing global forest extent and change from 2000 through 2013. We analyzed forest loss within and around mapped TDF cover mapped by Portillo-Quintero et al. 2010. In order to minimize errors in source data, we overlaid a 25 x 25 km grid on top of the regional dataset and conducted a cell by cell and country by country inspection at multiple scales using high resolution ancillary data. We identified trends in the clustering of space-time TDF deforestation data using ArcGIS, categorizing trends in: new, consecutive, intensifying, persistent, diminishing, sporadic, oscillating and historical hotspots (high frequency of deforestation events) and cold spots (low frequency of deforestation). In general, the region is experiencing less frequent deforestation events with a higher number of intensifying and new cold spots across TDF landscapes. However, an important number of intensifying and persistent hotspots exist so no general trend in forest loss was detected for the period 2001-2013, except for El Salvador which shows a significant decreasing trend in forest loss. Mexico, Nicaragua, Honduras and Guatemala are the major sources of intensifying, persistent and new deforestation hot spots. These were identified in the southern pacific coast and the Yucatan Peninsula in Mexico, northwestern Guatemala, both western and eastern Honduras and around Lake Nicaragua in Nicaragua.

High local genetic diversity of canine parvovirus from Ecuador.

Science.gov (United States)

Aldaz, Jaime; García-Díaz, Juan; Calleros, Lucía; Sosa, Katia; Iraola, Gregorio; Marandino, Ana; Hernández, Martín; Panzera, Yanina; Pérez, Ruben

2013-09-27

Canine parvovirus (CPV) comprises three antigenic variants (2a, 2b, and 2c) that are distributed globally with different frequencies and levels of genetic variability. CPVs from central Ecuador were herein analyzed to characterize the strains and to provide new insights into local viral diversity, evolution, and pathogenicity. Variant prevalence was analyzed by PCR and partial sequencing for 53 CPV-positive samples collected during 2011 and 2012. The full-length VP2 gene was sequenced in 24 selected strains and a maximum-likelihood phylogenetic tree was constructed using both Ecuadorian and worldwide strains. Ecuadorian CPVs have a remarkable genetic diversity that includes the circulation of all three variants and the existence of different evolutionary groups or lineages. CPV-2c was the most prevalent variant (54.7%), confirming the spread of this variant in America. Ecuadorian CPV-2c strains clustered in two lineages, which represent the first evidence of polyphyletic CPV-2c circulating in South America. CPV-2a strains constituted 41.5% of the samples and clustered in a single lineage. The two detected CPV-2b strains (3.8%) were clearly polyphyletic and appeared related to Ecuadorian CPV-2a or foreign CPV-2b strains. Besides the substitution at residue 426 that is used to identify the variants, two amino acid changes occurred in Ecuadorian strains: Val139Iso and Thr440Ser. Ser(440) occurred in a biologically relevant domain of VP2 and is here described for the first time in CPV. The associations of Ecuadorian CPV-2c and CPV-2a with clinical symptoms indicate that dull mentation, hemorrhagic gastroenteritis and hypothermia occurred more frequently in infection with CPV-2c than with CPV-2a. Copyright © 2013 Elsevier B.V. All rights reserved.

Red brome (Bromus rubens subsp. madritensis) in North America: Possible modes for early introductions, subsequent spread

Science.gov (United States)

Salo, L.F.

2005-01-01

Although invasions by exotic plants have increased dramatically as human travel and commerce have increased, few have been comprehensively described. Understanding the patterns of invasive species spread over space and time will help guide management activities and policy. Tracing the earliest appearances of an exotic plant reveals likely sites of introduction, paving the way for genetic studies to quantify founder events and identify potential source populations. Red brome (Bromus madritensis subsp. rubens) is a Mediterranean winter annual grass that has invaded even relatively undisturbed areas of western North America, where it threatens native plant communities. This study used herbarium records and contemporary published accounts to trace the early introductions and subsequent spread of red brome in western North America. The results challenge the most frequently cited sources describing the early history of this grass and suggest three possible modes for early introductions: the California Gold Rush and Central Valley wheat, southern California shipping, and northern California sheep. Subsequent periods of most rapid spread into new areas, from 1930 to 1942, and of greatest spread into new regions, during the past 50 years, coincide with warm Pacific Decadal Oscillation regimes, which are linked to increased winter precipitation in the southwestern USA and northern Mexico. Global environmental change, including increased atmospheric CO2 levels and N deposition, may be contributing to the success of red brome, relative to native species.

Low genetic variation and evidence of limited dispersal in the regionally important Belize manatee

Science.gov (United States)

Hunter, M.E.; Auil-Gomez, N. E.; Tucker, K.P.; Bonde, R.K.; Powell, J.; McGuire, P.M.

2010-01-01

The Antillean subspecies of the West Indian manatee Trichechus manatus is found throughout Central and South America and the Caribbean. Because of severe hunting pressure during the 17th through 19th centuries, only small populations of the once widespread aquatic mammal remain. Fortunately, protections in Belize reduced hunting in the 1930s and allowed the country's manatee population to become the largest breeding population in the Wider Caribbean. However, increasing and emerging anthropogenic threats such as coastal development, pollution, watercraft collision and net entanglement represent challenges to this ecologically important population. To inform conservation and management decisions, a comprehensive molecular investigation of the genetic diversity, relatedness and population structure of the Belize manatee population was conducted using mitochondrial and microsatellite DNA. Compared with other mammal populations, a low degree of genetic diversity was detected (HE=0.455; NA=3.4), corresponding to the small population size and long-term exploitation. Manatees from the Belize City Cayes and Southern Lagoon system were genetically different, with microsatellite and mitochondrial FST values of 0.029 and 0.078, respectively (P≤0.05). This, along with the distinct habitats and threats, indicates that separate protection of these two groups would best preserve the region's diversity. The Belize population and Florida subspecies appear to be unrelated with microsatellite and mitochondrial FST values of 0.141 and 0.63, respectively (P≤0.001), supporting the subspecies designations and suggesting low vagility throughout the northern Caribbean habitat. Further monitoring and protection may allow an increase in the Belize manatee genetic diversity and population size. A large and expanding Belize population could potentially assist in the recovery of other threatened or functionally extinct Central American Antillean manatee populations.

[Optimization of registry of deaths from chronic kidney disease in agricultural communities in Central America].

Science.gov (United States)

Escamilla-Cejudo, José Antonio; Báez, Jorge Lara; Peña, Rodolfo; Luna, Patricia Lorena Ruiz; Ordunez, Pedro

2016-11-01

Several Central American countries are seeing continued growth in the number of deaths from chronic kidney disease of nontraditional causes (CKDnT) among farm workers and there is underreporting. This report presents the results of a consensus process coordinated by the Pan American Health Organization/World Health Organization (PAHO/WHO), the United States Centers for Disease Control and Prevention (CDC), and the Latin American Society of Nephrology and Hypertension (SLANH). This consensus seeks to increase the probability of detecting and recording deaths from these causes. There has been recognition of the negative impact of the lack of a standardized instrument and the lack of training in the medical profession for adequate registration of the cause or causes of death. As a result of the consensus, the following has been proposed: temporarily use a code from the Codes for Special Purposes in the International Classification of Diseases (ICD-10); continue to promote use of the WHO international standardized instrument for recording causes and preceding events related to death; increase training of physicians responsible for filling out death certificates; take action to increase the coverage and quality of information on mortality; and create a decision tree to facilitate selection of CKDnT as a specific cause of death, while presenting the role that different regional and subregional mechanisms in the Region of the Americas should play in order to improve CKD and CKDnT mortality records.

Management training in global health education: a Health Innovation Fellowship training program to bring healthcare to low-income communities in Central America.

Science.gov (United States)

Prado, Andrea M; Pearson, Andy A; Bertelsen, Nathan S

2018-01-01

Interprofessional education is increasingly recognized as essential for health education worldwide. Although effective management, innovation, and entrepreneurship are necessary to improve health systems, business schools have been underrepresented in global health education. Central America needs more health professionals trained in health management and innovation to respond to health disparities, especially in rural communities. This paper explores the impact of the Health Innovation Fellowship (HIF), a new training program for practicing health professionals offered jointly by the Central American Healthcare Initiative and INCAE Business School, Costa Rica. Launched in 2014, HIF's goal is to create a network of highly trained interdisciplinary health professionals in competencies to improve health of Central American communities through better health management. The program's fellows carried out innovative healthcare projects in their local regions. The first three annual cohorts (total of 43 fellows) represented all health-related professions and sectors (private, public, and civil society) from six Central American countries. All fellows attended four 1-week, on-site modular training sessions, received ongoing mentorship, and stayed connected through formal and informal networks and webinars through which they exchange knowledge and support each other. CAHI stakeholders supported HIF financially. Impact evaluation of the three-year pilot training program is positive: fellows improved their health management skills and more than 50% of the projects found either financial or political support for their implementation. HIF's strengths include that both program leaders and trainees come from the Global South, and that HIF offers a platform to collaborate with partners in the Global North. By focusing on promoting innovation and management at a top business school in the region, HIF constitutes a novel capacity-building effort within global health education. HIF

The genetic legacy of multiple beaver reintroductions in Central Europe.

Science.gov (United States)

Frosch, Christiane; Kraus, Robert H S; Angst, Christof; Allgöwer, Rainer; Michaux, Johan; Teubner, Jana; Nowak, Carsten

2014-01-01

The comeback of the Eurasian beaver (Castor fiber) throughout western and central Europe is considered a major conservation success. Traditionally, several subspecies are recognised by morphology and mitochondrial haplotype, each linked to a relict population. During various reintroduction programs in the 20th century, beavers from multiple source localities were released and now form viable populations. These programs differed in their reintroduction strategies, i.e., using pure subspecies vs. mixed source populations. This inhomogeneity in management actions generated ongoing debates regarding the origin of present beaver populations and appropriate management plans for the future. By sequencing of the mitochondrial control region and microsatellite genotyping of 235 beaver individuals from five selected regions in Germany, Switzerland, Luxembourg, and Belgium we show that beavers from at least four source origins currently form admixed, genetically diverse populations that spread across the study region. While regional occurrences of invasive North American beavers (n = 20) were found, all but one C. fiber bore the mitochondrial haplotype of the autochthonous western Evolutionary Significant Unit (ESU). Considering this, as well as the viability of admixed populations and the fact that the fusion of different lineages is already progressing in all studied regions, we argue that admixture between different beaver source populations should be generally accepted.

Molecular and genetic basis for partial resistance of western white pine against Cronartium ribicola.

Science.gov (United States)

Jun-Jun Liu; Arezoo Zamany; Richard. Sniezko

2012-01-01

Western white pine (Pinus monticola Douglas ex D. Don) is an important forest species in North America. Forest genetics programs have been breeding for durable genetic resistance against white pine blister rust (WPBR) caused by Cronartium ribicola in the past few decades. As various genetic resistance resources are screened and...

Uniparental genetic heritage of belarusians: encounter of rare middle eastern matrilineages with a central European mitochondrial DNA pool.

Science.gov (United States)

Kushniarevich, Alena; Sivitskaya, Larysa; Danilenko, Nina; Novogrodskii, Tadeush; Tsybovsky, Iosif; Kiseleva, Anna; Kotova, Svetlana; Chaubey, Gyaneshwer; Metspalu, Ene; Sahakyan, Hovhannes; Bahmanimehr, Ardeshir; Reidla, Maere; Rootsi, Siiri; Parik, Jüri; Reisberg, Tuuli; Achilli, Alessandro; Hooshiar Kashani, Baharak; Gandini, Francesca; Olivieri, Anna; Behar, Doron M; Torroni, Antonio; Davydenko, Oleg; Villems, Richard

2013-01-01

Ethnic Belarusians make up more than 80% of the nine and half million people inhabiting the Republic of Belarus. Belarusians together with Ukrainians and Russians represent the East Slavic linguistic group, largest both in numbers and territory, inhabiting East Europe alongside Baltic-, Finno-Permic- and Turkic-speaking people. Till date, only a limited number of low resolution genetic studies have been performed on this population. Therefore, with the phylogeographic analysis of 565 Y-chromosomes and 267 mitochondrial DNAs from six well covered geographic sub-regions of Belarus we strove to complement the existing genetic profile of eastern Europeans. Our results reveal that around 80% of the paternal Belarusian gene pool is composed of R1a, I2a and N1c Y-chromosome haplogroups - a profile which is very similar to the two other eastern European populations - Ukrainians and Russians. The maternal Belarusian gene pool encompasses a full range of West Eurasian haplogroups and agrees well with the genetic structure of central-east European populations. Our data attest that latitudinal gradients characterize the variation of the uniparentally transmitted gene pools of modern Belarusians. In particular, the Y-chromosome reflects movements of people in central-east Europe, starting probably as early as the beginning of the Holocene. Furthermore, the matrilineal legacy of Belarusians retains two rare mitochondrial DNA haplogroups, N1a3 and N3, whose phylogeographies were explored in detail after de novo sequencing of 20 and 13 complete mitogenomes, respectively, from all over Eurasia. Our phylogeographic analyses reveal that two mitochondrial DNA lineages, N3 and N1a3, both of Middle Eastern origin, might mark distinct events of matrilineal gene flow to Europe: during the mid-Holocene period and around the Pleistocene-Holocene transition, respectively.

Genetic analysis of the Venezuelan Criollo horse.

Science.gov (United States)

Cothran, E G; Canelon, J L; Luis, C; Conant, E; Juras, R

2011-10-07

Various horse populations in the Americas have an origin in Spain; they are remnants of the first livestock introduced to the continent early in the colonial period (16th and 17th centuries). We evaluated genetic variability within the Venezuelan Criollo horse and its relationship with other horse breeds. We observed high levels of genetic diversity within the Criollo breed. Significant population differentiation was observed between all South American breeds. The Venezuelan Criollo horse showed high levels of genetic diversity, and from a conservation standpoint, there is no immediate danger of losing variation unless there is a large drop in population size.

Plant breeding and genetics newsletter, No. 24, January 2010

International Nuclear Information System (INIS)

2010-01-01

In the past biennium Plant Breeding and Genetics (PBG) subprogramme served 105 Member States through sixty-four national (30 Africa, 24 Asia and the Pacific, seven Latin America and the Caribbean, three Europe), seven regional (one Africa, four Asia and the Pacific, one Latin America and the Caribbean, one Europe) and one interregional Technical Cooperation Projects (TCPs), and six Coordinated Research Projects (CRPs) . Chosen highlights of these activities, you will find inside this issue

IAI Training in Climate and Health in the Americas

Science.gov (United States)

Aron, J. L.

2007-05-01

The Inter-American Institute for Global Change Research (IAI) has addressed training in climate and health in the Americas in two major ways. First, IAI supports students to engage in research training. A multi-country health activity funded by IAI was the collaborative research network (CRN) on Diagnostics and Prediction of Human Health Impacts in the Tropical Americas, which focused principally on the effect of El Nino/Southern Oscillation and other aspects of climate variability on mosquito-borne diseases malaria and dengue. The CRN involved students in Brazil, Mexico, Venezuela, Colombia and Jamaica. The CRN was also linked to other climate and health projects that used a similar approach. Second, IAI organizes training institutes to expand the network of global change research scientists and facilitate the transfer of global change research into practice. The IAI Training Institute on Climate and Health in the Americas was held on November 7 - 18, 2005 at the University of the West Indies in Kingston, Jamaica, engaging participants from the CRN and other programs in the Americas. The Training Institute's central objective was to help strengthen local and regional capacity to address the impacts of climate variability and climate change on human health in the populations of the Americas, particularly Latin America and the Caribbean. The Training Institute had three core components: Science; Applications; and Proposal Development for Seed Grants. Recommendations for future Training Institutes included incorporating new technologies and communicating with policy-makers to develop more proactive societal strategies to manage risks.

Development and application of microsatellites in Carcinus maenas: genetic differentiation between Northern and Central Portuguese populations.

Directory of Open Access Journals (Sweden)

Sónia Pascoal

Full Text Available Carcinus maenas, the common shore crab of European coastal waters, has recently gained notoriety due to its globally invasive nature associated with drastic ecological and economic effects. The native ubiquity and worldwide importance of C. maenas has resulted in it becoming one of the best-studied estuarine crustacean species globally. Accordingly, there is significant interest in investigating the population genetic structure of this broadly distributed crab along European and invaded coastlines. Here, we developed polymerase chain reaction (PCR primers for one dinucleotide and two trinucleotide microsatellite loci, resulting from an enrichment process based on Portuguese populations. Combining these three new markers with six existing markers, we examined levels of genetic diversity and population structure of C. maenas in two coastal regions from Northern and Central Portugal. Genotypes showed that locus polymorphism ranged from 10 to 42 alleles (N = 135 and observed heterozygosity per locus ranged from 0.745 to 0.987 with expected heterozygosity ranging from 0.711 to 0.960; values typical of marine decapods. The markers revealed weak, but significant structuring among populations (global F(ST = 0.004 across a 450 km (over-water distance spatial scale. Combinations of these and existing markers will be useful for studying population genetic parameters at a range of spatial scales of C. maenas throughout its expanding species range.

Five cases of acute Zika virus infection in French women of reproductive age returning from Central and South America.

Science.gov (United States)

Penot, P; Balavoine, S; Leplatois, A; Brichler, S; Leparc-Goffart, I; Alloui, A-C; Flusin, O; Guilleminot, J; Amellou, M; Molina, J-M

2017-08-01

The favorable season for Aedes albopictus circulation has started in Europe and may lead to autochthonous transmission of Zika virus. Health care providers should be familiar with evocative clinical presentations and able to give updated information to women of reproductive age infected by Zika virus. We report five laboratory-confirmed Zika virus infections imported to metropolitan France from Central and South America between January and April, 2016. The five young women were not connected and not pregnant; common presentation combined a rash with persistent arthralgia. Zika virus was identified by RT-PCR from serum or urines, between two and eight days after the onset of the symptoms. As the duration of potential materno-foetal infectivity is still unknown, we were unable to answer with certitude to the patients' questions about the time interval to respect before attempting a pregnancy: one of them became pregnant one month after the diagnosis. Copyright © 2016 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier SAS. All rights reserved.

[The cholera epidemic in Latin America].

Science.gov (United States)

Olsvik, O

1992-05-30

An outbreak of cholera started in Peru in January 1991 and spread through most Latin American countries within a year. This was the first known epidemic of cholera in America for more than a century. In 1991, 321,334 persons were reported to have cholera in Peru, 119,063 were hospitalized, and 2,906 died. Other countries like Ecuador, Colombia, Guatemala, Brazil, Mexico, Bolivia, Chile, El Salvador, Venezuela and Honduras were also affected, but these countries combined accounted for only 20% of the cases registered in Peru. In April 1992, all Latin American countries except Uruguay, Paraguay and French Guyana have reported cholera. The mortality rate for the epidemic in Latin America was only 1%, mainly owing to good oral rehydration treatment provided by Local health services and the Pan American Health Organization. The causative organism was Vibrio cholerae, serogroup O1, serotype Inaba (and Ogawa) of the El Tor biotype. Genetic characterization shows this strain to be unique, and the designation is reserved for the Latin American strain, distinguishing it from the other El Tor isolates from the 7th pandemic.

The Genetic Contribution of West-African Ancestry to Protection against Central Obesity in African-American Men but Not Women: Results from the ARIC and MESA Studies.

Science.gov (United States)

Klimentidis, Yann C; Arora, Amit; Zhou, Jin; Kittles, Rick; Allison, David B

2016-01-01

Over 80% of African-American (AA) women are overweight or obese. A large racial disparity between AA and European-Americans (EA) in obesity rates exists among women, but curiously not among men. Although socio-economic and/or cultural factors may partly account for this race-by-sex interaction, the potential involvement of genetic factors has not yet been investigated. Among 2814 self-identified AA in the Atherosclerosis Risk in Communities study, we estimated each individual's degree of West-African genetic ancestry using 3437 ancestry informative markers. We then tested whether sex modifies the association between West-African genetic ancestry and body mass index (BMI), waist-circumference (WC), and waist-to-hip ratio (WHR), adjusting for income and education levels, and examined associations of ancestry with the phenotypes separately in males and females. We replicated our findings in the Multi-Ethnic Study of Atherosclerosis (n = 1611 AA). In both studies, we find that West-African ancestry is negatively associated with obesity, especially central obesity, among AA men, but not among AA women (pinteraction = 4.14 × 10(-5) in pooled analysis of WHR). In conclusion, our results suggest that the combination of male gender and West-African genetic ancestry is associated with protection against central adiposity, and suggest that the large racial disparity that exists among women, but not men, may be at least partly attributed to genetic factors.

Magmas with slab fluid and decompression melting signatures coexisting in the Gulf of Fonseca: Evidence from Isla El Tigre volcano (Honduras, Central America)

Science.gov (United States)

Mattioli, Michele; Renzulli, Alberto; Agostini, Samuele; Lucidi, Roberto

2016-01-01

Isla El Tigre volcano is located in the Gulf of Fonseca (Honduras) along the Central America volcanic front, where a significant change in the strike of the volcanic chain is observed. The studied samples of this poorly investigated volcano are mainly subalkaline basic to intermediate lavas (basalts and basaltic andesites) and subordinate subalkaline/alkaline transitional basalts, both having the typical mineralogical and geochemical characteristics of arc volcanic rocks. On the basis of petrographic and geochemical features, two groups of rocks have been distinguished. Lavas from the main volcanic edifice are highly porphyritic and hy-qz normative, and have lower MgO contents ( 5 wt.%), are ol-hy normative and show lower HFSE depletions relative to LILE and LREE, with lower Ba/La, Ba/Nb and Zr/Nb ratios. This suggests that mantle-derived magmas were not produced by the same process throughout the activity of the volcano. The bulk rock geochemistry and 87Sr/86Sr (0.70373-0.70382), 143Nd/144Nd (0.51298-0.51301), 206Pb/204Pb (18.55-18.58), 207Pb/204Pb (15.54-15.56) and 208Pb/204Pb (38.23-38.26) isotopic data of Isla El Tigre compared with the other volcanoes of the Gulf of Fonseca and all available literature data for Central America suggests that this stratovolcano was mainly built by mantle-derived melts driven by slab-derived fluid-flux melting, while magmas erupted through its parasitic cones have a clear signature of decompression melting with minor slab contribution. The coexistence of these two different mantle melting generation processes is likely related to the complex geodynamic setting of the Gulf of Fonseca, where the volcanic front changes direction by ca. 30° and two fundamental tectonic structures of the Chortis continental block, mainly the N-S Honduras Depression and the NE-SW Guayape Fault Zone, cross each other.

Do minimum wages reduce poverty? Evidence from Central America ...

International Development Research Centre (IDRC) Digital Library (Canada)

In all three countries, these multiple minimum wages are negotiated among representatives of the central government, labour unions and the chambers of commerce. Minimum wage legislation applies to all private-sector employees, but in all three countries a large part of the work force is self-employed or works as unpaid ...

Genetic species identification in weatherfish and first molecular confirmation of Oriental Weatherfish Misgurnus anguillicaudatus (Cantor, 1842 in Central Europe

Directory of Open Access Journals (Sweden)

Belle Christina C.

2017-01-01

Full Text Available The Oriental Weatherfish is considered a globally invasive fish species. In Europe, several reported feral populations of Oriental Weatherfish display an overlapping distribution range with native weatherfish Misgurnus fossilis, a declining species of international conservation and aquatic management concern. Morphologically distinguishing the different weatherfish species can be difficult, as their coloration is highly variable, many species reveal high phenotypic plasticity, and morphological traits like coloration might be not obvious or might be degraded during field sampling and after preservation. Herein, we analysed suspicious weatherfish specimens from southern Germany, demonstrating the usefulness of molecular genetic species identifications in this genus. We present the first molecular genetic species record of Misgurnus anguillicaudatus in Central Europe, and confirm the range expansion of Oriental Weatherfish into the river Inn catchment in southern Germany. As accurate species identification is crucial both in the context of monitoring and conserving native endangered species, and in early detection and prevention of biological invasion, we suggest the standard use of genetic species identification if morphological traits are not obvious.

300 years of hydrological records and societal responses to droughts and floods on the Pacific coast of Central America

Directory of Open Access Journals (Sweden)

A. Guevara-Murua

2018-02-01

Full Text Available The management of hydrological extremes and impacts on society is inadequately understood because of the combination of short-term hydrological records, an equally short-term assessment of societal responses and the complex multi-directional relationships between the two over longer timescales. Rainfall seasonality and inter-annual variability on the Pacific coast of Central America is high due to the passage of the Inter Tropical Convergence Zone (ITCZ and the El Niño–Southern Oscillation (ENSO. Here we reconstruct hydrological variability and demonstrate the potential for assessing societal impacts by drawing on documentary sources from the cities of Santiago de Guatemala (now Antigua Guatemala and Guatemala de la Asunción (now Guatemala City over the period from 1640 to 1945. City and municipal council meetings provide a rich source of information dating back to the beginning of Spanish colonisation in the 16th century. We use almost continuous sources from 1640 AD onwards, including > 190 volumes of Actas de Cabildo and Actas Municipales (minutes of meetings of the city and municipal councils held by the Archivo Histórico de la Municipalidad de Antigua Guatemala (AHMAG and the Archivo General de Centro América (AGCA in Guatemala City. For this 305-year period (with the exception of a total of 11 years during which the books were either missing or damaged, information relating to Catholic rogation ceremonies and reports of flooding events and crop shortages were used to classify the annual rainy season (May to October on a five-point scale from very wet to very dry. In total, 12 years of very wet conditions, 25 years of wetter than usual conditions, 34 years of drier conditions and 21 years of very dry conditions were recorded. An extended drier period from the 1640s to the 1740s was identified and two shorter periods (the 1820s and the 1840s were dominated by dry conditions. Wetter conditions dominated the 1760s–1810s and

Introduction: seismology and earthquake engineering in Mexico and Central and South America.

Science.gov (United States)

Espinosa, A.F.

1982-01-01

The results from seismological studies that are used by the engineering community are just one of the benefits obtained from research aimed at mitigating the earthquake hazard. In this issue of Earthquake Information Bulletin current programs in seismology and earthquake engineering, seismic networks, future plans and some of the cooperative programs with different internation organizations are described by Latin-American seismologists. The article describes the development of seismology in Latin America and the seismological interest of the OAS. -P.N.Chroston

Genetic characterization of local Criollo pig breeds from the Americas using microsatellite markers.

Science.gov (United States)

Revidatti, M A; Delgado Bermejo, J V; Gama, L T; Landi Periati, V; Ginja, C; Alvarez, L A; Vega-Pla, J L; Martínez, A M

2014-11-01

Little is known about local Criollo pig genetic resources and relationships among the various populations. In this paper, genetic diversity and relationships among 17 Criollo pig populations from 11 American countries were assessed with 24 microsatellite markers. Heterozygosities, F-statistics, and genetic distances were estimated, and multivariate, genetic structure and admixture analyses were performed. The overall means for genetic variability parameters based on the 24 microsatellite markers were the following: mean number of alleles per locus of 6.25 ± 2.3; effective number of alleles per locus of 3.33 ± 1.56; allelic richness per locus of 4.61 ± 1.37; expected and observed heterozygosity of 0.62 ± 0.04 and 0.57 ± 0.02, respectively; within-population inbreeding coefficient of 0.089; and proportion of genetic variability accounted for by differences among breeds of 0.11 ± 0.01. Genetic differences were not significantly associated with the geographical location to which breeds were assigned or their country of origin. Still, the NeighborNet dendrogram depicted the clustering by geographic origin of several South American breeds (Criollo Boliviano, Criollo of northeastern Argentina wet, and Criollo of northeastern Argentina dry), but some unexpected results were also observed, such as the grouping of breeds from countries as distant as El Salvador, Mexico, Ecuador, and Cuba. The results of genetic structure and admixture analyses indicated that the most likely number of ancestral populations was 11, and most breeds clustered separately when this was the number of predefined populations, with the exception of some closely related breeds that shared the same cluster and others that were admixed. These results indicate that Criollo pigs represent important reservoirs of pig genetic diversity useful for local development as well as for the pig industry.

Genetic polymorphism and population structure of Echinococcus ortleppi.

Science.gov (United States)

Addy, F; Wassermann, M; Banda, F; Mbaya, H; Aschenborn, J; Aschenborn, O; Koskei, P; Umhang, G; DE LA Rue, M; Elmahdi, I E; Mackenstedt, U; Kern, P; Romig, T

2017-04-01

The zoonotic cestode Echinococcus ortleppi (Lopez-Neyra and Soler Planas, 1943) is mainly transmitted between dogs and cattle. It occurs worldwide but is only found sporadically in most regions, with the notable exception of parts of southern Africa and South America. Its epidemiology is little understood and the extent of intraspecific variability is unknown. We have analysed in the present study the genetic diversity among 178 E. ortleppi isolates from sub-Saharan Africa, Europe and South America using the complete mitochondrial cox1 (1608 bp) and nad1 (894 bp) DNA sequences. Genetic polymorphism within the loci revealed 15 cox1 and six nad1 haplotypes, respectively, and 20 haplotypes of the concatenated genes. Presence of most haplotypes was correlated to geographical regions, and only one haplotype had a wider spread in both eastern and southern Africa. Intraspecific microvariance was low in comparison with Echinococcus granulosus sensu stricto, despite the wide geographic range of examined isolates. In addition, the various sub-populations showed only subtle deviation from neutrality and were mostly genetically differentiated. This is the first insight into the population genetics of the enigmatic cattle adapted Echinococcus ortleppi. It, therefore, provides baseline data for biogeographical comparison among E. ortleppi endemic regions and for tracing its translocation paths.

Invasion genetics of emerald ash borer in North America

Science.gov (United States)

Alicia M. Bray; Leah S. Bauer; Robert A. Haack; Therese Poland; James J. Smith

2006-01-01

Emerald ash borer (EAB) was first detected in Michigan and Canada in 2002. Efforts to eradicate this destructive pest by federal and state regulatory agencies continue. Knowledge of EAB genetics will be useful in understanding the invasion dynamics of the beetle and to help identify geographic localities of potential biocontrol agents.

Crop yield, genetic parameter estimation and selection of sacha inchi in central Amazon

Directory of Open Access Journals (Sweden)

Mágno Sávio Ferreira Valente

2017-06-01

Full Text Available In Brazil, sacha inchi oil is produced by hand from plant materials with no breeding or detailed information about the chemical composition of seeds. In addition, most of the current information on the agronomic traits of this species originates from research carried out in the Peruvian Amazon. In order to promote the research and cultivation of sacha inchi in the Brazilian territory, this study aimed to analyze, in the central Amazon region, different accessions of this oilseed for characteristics of production and quality of fruits and seeds, as well as to estimate genetic parameters, through mixed models, with identification of superior accessions, for breeding purposes. A total of 37 non-domesticated accessions were evaluated in a randomized block design, with five replications and two plants per plot. The average oil content in seeds was 29.07 % and unsaturated fatty acids amounted to 91.5 % of the total fat content. For the yield traits, the estimates of individual broad-sense heritability were moderate (~0.33, while the heritability based on the average of progenies resulted in a selective accuracy of approximately 0.85. The use of the selection index provided simultaneous gains for yield traits (> 40 % and oil yield. A high genetic variability was observed for the main traits of commercial interest for the species, as well as promising perspectives for the development of superior varieties for agro-industrial use.

Genetics Home Reference: PURA syndrome

Science.gov (United States)

... TJ, Vreeburg M, Rouhl RPW, Stevens SJC, Stegmann APA, Schieving J, Pfundt R, van Dijk K, Smeets ... article on PubMed Central More from Genetics Home Reference Bulletins Genetics Home Reference Celebrates Its 15th Anniversary ...

The new Central American seismic hazard zonation: Mutual consensus based on up to day seismotectonic framework

Science.gov (United States)

Alvarado, Guillermo E.; Benito, Belén; Staller, Alejandra; Climent, Álvaro; Camacho, Eduardo; Rojas, Wilfredo; Marroquín, Griselda; Molina, Enrique; Talavera, J. Emilio; Martínez-Cuevas, Sandra; Lindholm, Conrad

2017-11-01

Central America is one of the most active seismic zones in the World, due to the interaction of five tectonic plates (North America, Caribbean, Coco, Nazca and South America), and its internal deformation, which generates almost one destructive earthquakes (5.4 ≤ Mw ≤ 8.1) every year. A new seismological zonation for Central America is proposed based on seismotectonic framework, a geological context (tectonic and geological maps), geophysical and geodetic evidence (gravimetric maps, magnetometric, GPS observations), and previous works. As a main source of data a depurated earthquake catalog was collected covering the period from 1522 to 2015. This catalog was homogenized to a moment magnitude scale (Mw). After a careful analysis of all the integrated geological and seismological information, the seismogenic zones were established into seismic areas defined by similar patterns of faulting, seismicity, and rupture mechanism. The tectonic environment has required considering seismic zones in two particular seismological regimes: a) crustal faulting (including local faults, major fracture zones of plate boundary limits, and thrust fault of deformed belts) and b) subduction, taking into account the change in the subduction angle along the trench, and the type and location of the rupture. The seismicity in the subduction zone is divided into interplate and intraplate inslab seismicity. The regional seismic zonation proposed for the whole of Central America, include local seismic zonations, avoiding discontinuities at the national boundaries, because of a consensus between the 7 countries, based on the cooperative work of specialists on Central American seismotectonics and related topics.

Psychological impact of von Hippel-Lindau genetic screening in patients with a previous history of hemangioblastoma of the central nervous system.

Science.gov (United States)

Rochette, Claire; Baumstarck, Karine; Canoni-Zattara, Hélène; Abdullah, Ahmad Esmaeel; Figarella-Branger, Dominique; Pertuit, Morgane; Barlier, Anne; Castinetti, Frédéric; Pacak, Karel; Metellus, Philippe; Taïeb, David

2018-05-15

Von Hippel-Lindau (VHL) syndrome is a hereditary cancer syndrome characterized by a high risk of developing benign and malignant tumors, including central nervous system hemangioblastomas (CNS HBs). For an early diagnosis of VHL, before the occurrence of cancers (especially renal cell carcinoma), it is of huge importance to initiate VHL genetic testing in at-risk patients. The aim of the study was to assess the psychological impact of VHL genetic testing in patients previously diagnosed with a CNS HB. From 1999 until 2015, 55 patients underwent surgery for CNS HBs. Eleven patients were already screened for VHL mutations and 3 patients deceased before the start of the study. From the remaining 42 patients, 24 were accepted to be enrolled in the study. Assessment of psychological impact of VHL genetic testing was performed by measuring anxiety levels, mood disorders, quality of life, and psychological consequences of genetic screening. Twenty-one of the enrolled 24 patients underwent VHL genetic testing and 12 patients came back for the communication of positive genetic results. The baseline psychological status did not differ between these 2 groups. Patients who attended the visit of communication of genetic results had similar anxiety levels compared to those who had not. Furthermore, they also experienced an improvement in the level of anxiety and two QoL dimension scores compared to their baseline status. In summary, there is no evidence of a negative psychosocial impact of VHL genetic testing in patients with a previous history of CNS HB. We, therefore, recommend the recall of patients who have not been previously screened.

Global genetics and invasion history of the potato powdery scab pathogen, Spongospora subterranea f.sp. subterranea.

Science.gov (United States)

Gau, Rebecca D; Merz, Ueli; Falloon, Richard E; Brunner, Patrick C

2013-01-01

Spongospora subterranea f. sp. subterranea (Sss) causes two diseases on potato (Solanum tuberosum), lesions on tubers and galls on roots, which are economically important worldwide. Knowledge of global genetic diversity and population structure of pathogens is essential for disease management including resistance breeding. A combination of microsatellite and DNA sequence data was used to investigate the structure and invasion history of Sss. South American populations (four countries, 132 samples) were consistently more diverse than those from all other regions (15 countries, 566 samples), in agreement with the hypothesis that Sss originated in South America where potato was domesticated. A substantial genetic differentiation was found between root and tuber-derived samples from South America. Estimates of past and recent gene flow suggested that Sss was probably introduced from South America into Europe. Subsequently, Europe is likely to have been the recent source of migrants of the pathogen, acting as a "bridgehead" for further global dissemination. Quarantine measures must continue to be focussed on maintaining low global genetic diversity and avoiding exchange of genetic material between the native and introduced regions. Nevertheless, the current low global genetic diversity of Sss allows potato breeders to select for resistance, which is likely to be durable.

Global genetics and invasion history of the potato powdery scab pathogen, Spongospora subterranea f.sp. subterranea.

Directory of Open Access Journals (Sweden)

Rebecca D Gau

Full Text Available Spongospora subterranea f. sp. subterranea (Sss causes two diseases on potato (Solanum tuberosum, lesions on tubers and galls on roots, which are economically important worldwide. Knowledge of global genetic diversity and population structure of pathogens is essential for disease management including resistance breeding. A combination of microsatellite and DNA sequence data was used to investigate the structure and invasion history of Sss. South American populations (four countries, 132 samples were consistently more diverse than those from all other regions (15 countries, 566 samples, in agreement with the hypothesis that Sss originated in South America where potato was domesticated. A substantial genetic differentiation was found between root and tuber-derived samples from South America. Estimates of past and recent gene flow suggested that Sss was probably introduced from South America into Europe. Subsequently, Europe is likely to have been the recent source of migrants of the pathogen, acting as a "bridgehead" for further global dissemination. Quarantine measures must continue to be focussed on maintaining low global genetic diversity and avoiding exchange of genetic material between the native and introduced regions. Nevertheless, the current low global genetic diversity of Sss allows potato breeders to select for resistance, which is likely to be durable.

Genetic and environmental factors affecting birth size variation

DEFF Research Database (Denmark)

Yokoyama, Yoshie; Jelenkovic, Aline; Hur, Yoon-Mi

2018-01-01

Background: The genetic architecture of birth size may differ geographically and over time. We examined differences in the genetic and environmental contributions to birthweight, length and ponderal index (PI) across geographical-cultural regions (Europe, North America and Australia, and East Asia......) and across birth cohorts, and how gestational age modifies these effects. Methods: Data from 26 twin cohorts in 16 countries including 57 613 monozygotic and dizygotic twin pairs were pooled. Genetic and environmental variations of birth size were estimated using genetic structural equation modelling....... Results: The variance of birthweight and length was predominantly explained by shared environmental factors, whereas the variance of PI was explained both by shared and unique environmental factors. Genetic variance contributing to birth size was small. Adjusting for gestational age decreased...

Las Migraciones en el Proceso de Integracion de las Americas: Seminario Internacional (Migration in the Integration Process in the Americas: International Seminar). Conference report.

Science.gov (United States)

Berglund, S

1993-01-01

This conference report of the Centro de Estudios Migratorios Latinoamericanos and the Center for Migration Studies pertains to meetings held in August 1992. Summary information on migration movements in Latin America is presented by region and subject. The topic of integration in the Americas was presented by Mr. Lelio Marmora. Other topics and presenters include the new Colombian Migration Policy (Mr. Carlos Adolfo Arenas), the integration policies in Central America (Mr. Pilar Norza of Costa Rica, Raimundo Alvarado of El Salvador, and Luis Armando Gusman of Nicaragua), the Andean Pact agreements (representatives of each country), US immigration policy (Charles B. Keely), the Mexican integration with Latin America and immigration to the US (Jorge Bustamante), migration to Bolivia and Argentina and Chile, and transnationalism in the Caribbean (Professor Andre Corten). Migration policy needs to be tailored specifically to the situation in Latin America, and greater attention needs to be devoted to labor migrants' rights and working conditions. There are still fundamental differences among countries in policies regarding the free circulation of persons across borders. There is a division among those who support migration and those who are realists. National sovereignty issues are solvable because of a common national past and a relatively homogenous population. Another opinion is that Latin America is more diverse than commonly recognized. Capital is protected more in international agreements than is migrant labor. Regional integration for the US does mean immigration from Mexico. The US sees Mexican migration as a policy problem, and Mexico sees migration as a labor opportunity.

Journal of Genetics | Indian Academy of Sciences

Indian Academy of Sciences (India)

Feral cattle residing in Chirikof Island, Alaska, are relatively distinct from breeds used in commercial production in North America. However, preliminary evidence suggested that they exhibit substantial genetic relationship with cattle fromYakutian region of Siberia. Thus, our objective was to further elucidate quantify the ...

Genetic Diversification and Dispersal of Taro (Colocasia esculenta (L. Schott.

Directory of Open Access Journals (Sweden)

H Chaïr

Full Text Available Taro (Colocasia esculenta (L. Schott is widely distributed in tropical and sub-tropical areas. However, its origin, diversification and dispersal remain unclear. While taro genetic diversity has been documented at the country and regional levels in Asia and the Pacific, few reports are available from Americas and Africa where it has been introduced through human migrations. We used eleven microsatellite markers to investigate the diversity and diversification of taro accessions from nineteen countries in Asia, the Pacific, Africa and America. The highest genetic diversity and number of private alleles were observed in Asian accessions, mainly from India. While taro has been diversified in Asia and the Pacific mostly via sexual reproduction, clonal reproduction with mutation appeared predominant in African and American countries investigated. Bayesian clustering revealed a first genetic group of diploids from the Asia-Pacific region and to a second diploid-triploid group mainly from India. Admixed cultivars between the two genetic pools were also found. In West Africa, most cultivars were found to have originated from India. Only one multi-locus lineage was assigned to the Asian pool, while cultivars in Madagascar originated from India and Indonesia. The South African cultivars shared lineages with Japan. The Caribbean Islands cultivars were found to have originated from the Pacific, while in Costa Rica they were from India or admixed between Indian and Asian groups. Taro dispersal in the different areas of Africa and America is thus discussed in the light of available records of voyages and settlements.

Lower Miocene stratigraphy along the Panama Canal and its bearing on the Central American Peninsula.

Directory of Open Access Journals (Sweden)

Michael Xavier Kirby

Full Text Available Before the formation of the Central American Isthmus, there was a Central American Peninsula. Here we show that southern Central America existed as a peninsula as early as 19 Ma, based on new lithostratigraphic, biostratigraphic and strontium chemostratigraphic analyses of the formations exposed along the Gaillard Cut of the Panama Canal. Land mammals found in the Miocene Cucaracha Formation have similar body sizes to conspecific taxa in North America, indicating that there existed a terrestrial connection with North America that allowed gene flow between populations during this time. How long did this peninsula last? The answer hinges on the outcome of a stratigraphic dispute: To wit, is the terrestrial Cucaracha Formation older or younger than the marine La Boca Formation? Previous stratigraphic studies of the Panama Canal Basin have suggested that the Cucaracha Formation lies stratigraphically between the shallow-marine Culebra Formation and the shallow-to-upper-bathyal La Boca Formation, the latter containing the Emperador Limestone. If the La Boca Formation is younger than the Cucaracha Formation, as many think, then the peninsula was short-lived (1-2 m.y., having been submerged in part by the transgression represented by the overlying La Boca Formation. On the other hand, our data support the view that the La Boca Formation is older than the Cucaracha Formation. Strontium dating shows that the La Boca Formation is older (23.07 to 20.62 Ma than both the Culebra (19.83-19.12 Ma and Cucaracha (Hemingfordian to Barstovian North American Land Mammal Ages; 19-14 Ma formations. The Emperador Limestone is also older (21.24-20.99 Ma than the Culebra and Cucaracha formations. What has been called the "La Boca Formation" (with the Emperador Limestone, is re-interpreted here as being the lower part of the Culebra Formation. Our new data sets demonstrate that the main axis of the volcanic arc in southern Central America more than likely existed as a

Lower Miocene stratigraphy along the Panama Canal and its bearing on the Central American Peninsula.

Science.gov (United States)

Kirby, Michael Xavier; Jones, Douglas S; MacFadden, Bruce J

2008-07-30

Before the formation of the Central American Isthmus, there was a Central American Peninsula. Here we show that southern Central America existed as a peninsula as early as 19 Ma, based on new lithostratigraphic, biostratigraphic and strontium chemostratigraphic analyses of the formations exposed along the Gaillard Cut of the Panama Canal. Land mammals found in the Miocene Cucaracha Formation have similar body sizes to conspecific taxa in North America, indicating that there existed a terrestrial connection with North America that allowed gene flow between populations during this time. How long did this peninsula last? The answer hinges on the outcome of a stratigraphic dispute: To wit, is the terrestrial Cucaracha Formation older or younger than the marine La Boca Formation? Previous stratigraphic studies of the Panama Canal Basin have suggested that the Cucaracha Formation lies stratigraphically between the shallow-marine Culebra Formation and the shallow-to-upper-bathyal La Boca Formation, the latter containing the Emperador Limestone. If the La Boca Formation is younger than the Cucaracha Formation, as many think, then the peninsula was short-lived (1-2 m.y.), having been submerged in part by the transgression represented by the overlying La Boca Formation. On the other hand, our data support the view that the La Boca Formation is older than the Cucaracha Formation. Strontium dating shows that the La Boca Formation is older (23.07 to 20.62 Ma) than both the Culebra (19.83-19.12 Ma) and Cucaracha (Hemingfordian to Barstovian North American Land Mammal Ages; 19-14 Ma) formations. The Emperador Limestone is also older (21.24-20.99 Ma) than the Culebra and Cucaracha formations. What has been called the "La Boca Formation" (with the Emperador Limestone), is re-interpreted here as being the lower part of the Culebra Formation. Our new data sets demonstrate that the main axis of the volcanic arc in southern Central America more than likely existed as a peninsula

Assessment of Genetic Variation Among East African Cercospora ...

African Journals Online (AJOL)

Rapid flagement length polymorphism (RFLP) and amplified flagement length polymorphism (AFLP) analyses were used to study genetic diversity of Cercospora zeae-maydis isolates collected from Uganda, Kenya and Rwanda. For comparative purposes, isolates from Zimbabwe and the United States of America (USA) ...

Phenotypic and genotypic heterogeneity among Streptococcus iniae isolates recovered from cultured and wild fish in North America, Central America and the Caribbean Islands

Science.gov (United States)

Streptococcus iniae, the etiological agent of streptococcosis in fish, is an important pathogen of cultured and wild fish worldwide. During the last decade outbreaks of streptococcosis have occurred in a wide range of cultured and wild fish in the Americas and Caribbean islands. To gain a better und...

The genetic prehistory of the New World Arctic.

Science.gov (United States)

Raghavan, Maanasa; DeGiorgio, Michael; Albrechtsen, Anders; Moltke, Ida; Skoglund, Pontus; Korneliussen, Thorfinn S; Grønnow, Bjarne; Appelt, Martin; Gulløv, Hans Christian; Friesen, T Max; Fitzhugh, William; Malmström, Helena; Rasmussen, Simon; Olsen, Jesper; Melchior, Linea; Fuller, Benjamin T; Fahrni, Simon M; Stafford, Thomas; Grimes, Vaughan; Renouf, M A Priscilla; Cybulski, Jerome; Lynnerup, Niels; Lahr, Marta Mirazon; Britton, Kate; Knecht, Rick; Arneborg, Jette; Metspalu, Mait; Cornejo, Omar E; Malaspinas, Anna-Sapfo; Wang, Yong; Rasmussen, Morten; Raghavan, Vibha; Hansen, Thomas V O; Khusnutdinova, Elza; Pierre, Tracey; Dneprovsky, Kirill; Andreasen, Claus; Lange, Hans; Hayes, M Geoffrey; Coltrain, Joan; Spitsyn, Victor A; Götherström, Anders; Orlando, Ludovic; Kivisild, Toomas; Villems, Richard; Crawford, Michael H; Nielsen, Finn C; Dissing, Jørgen; Heinemeier, Jan; Meldgaard, Morten; Bustamante, Carlos; O'Rourke, Dennis H; Jakobsson, Mattias; Gilbert, M Thomas P; Nielsen, Rasmus; Willerslev, Eske

2014-08-29

The New World Arctic, the last region of the Americas to be populated by humans, has a relatively well-researched archaeology, but an understanding of its genetic history is lacking. We present genome-wide sequence data from ancient and present-day humans from Greenland, Arctic Canada, Alaska, Aleutian Islands, and Siberia. We show that Paleo-Eskimos (~3000 BCE to 1300 CE) represent a migration pulse into the Americas independent of both Native American and Inuit expansions. Furthermore, the genetic continuity characterizing the Paleo-Eskimo period was interrupted by the arrival of a new population, representing the ancestors of present-day Inuit, with evidence of past gene flow between these lineages. Despite periodic abandonment of major Arctic regions, a single Paleo-Eskimo metapopulation likely survived in near-isolation for more than 4000 years, only to vanish around 700 years ago. Copyright © 2014, American Association for the Advancement of Science.

Population data for 12 Y-chromosome STR loci in a sample from Honduras.

Science.gov (United States)

Matamoros, Mireya; Yurrebaso, Iñaki; Gusmão, Leonor; García, Oscar

2009-09-01

Haplotype, allele frequencies and population data of 12 Y-chromosome STR loci DYS19, DYS385, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438 and DYS439 were determined from a sample of 128 unrelated male individuals from Honduras, Central America. A total of 112 haplotypes were identified by the 12 Y-STR loci of which 98 were unique. The haplotype diversity (98.99%) and the proportion of different haplotypes (87.50%) were estimated. Genetic distances were calculated between Honduras and other populations from Southern and Central America, Europe and Africa. The analysis of a Multi Dimensional Scaling (MDS) plot, based on pairwise R(ST) genetic distances, allowed to conclude that Honduras is highly differentiated from the African samples (0.343Honduras showed a lower genetic distance to the European cluster (composed by European and South American general population samples from Brazil, Argentina, Colombia and Venezuela) than to the Central American cluster (Mexico and El Salvador).

Outline of tectonic geology of the cenozoic Pacific volcanic zone concerned with geothermal areas in the central America; Chubei ni okeru chinetsutai wo tomonau shinseidai Taiheiyo kazantai no chishitsu gaisetsu

Energy Technology Data Exchange (ETDEWEB)

Yamasaki, T [Kyushu University, Fukuoka (Japan); Matsumoto, Y [Yamaguchi University, Yamaguchi (Japan)

1994-09-16

For the purpose of technological cooperation on geothermal development, investigations and discussions have been given on the geological background in the geothermal areas in Central America where the Pacific volcanic zone stretches. The geology in Central America is divided largely into three geological structures distributed in a band form in the east-west direction. Among these structure, the Pacific Volcanic Province is a Caenozoic volcanic area ranging along the Pacific Ocean coast in the south-east direction, where young and active Quarternary volcanoes are lined straight over a distance of 1,400 km. The geological structure is such that continuously traceable rift valley or pit structure agrees with the array of volcanoes. The long and wide rift valley that governs this volcanic activity forms the base of the geothermal areas dotted in the above structure. Guatemala had been proceeding with a 24-MW power plant plan in Zunil, the most important point, but the construction has been delayed because of a landslide that caused impediment to the productive wells. The plant completion is now scheduled for 1995. El Salvador is the most advanced country in geothermal power generation, which operates three plants in the Ahuachapa geothermal area, with the output reaching 95 MW. The geothermal condition per production well is 110 tons per hour at 250{degree}C. Nicaragua had been successful in generating power of 70 KW with two plants in Momtombo by 1989. 22 refs., 8 figs., 4 tabs.

Arctic-midlatitude weather linkages in North America

Science.gov (United States)

Overland, James E.; Wang, Muyin

2018-06-01

There is intense public interest in whether major Arctic changes can and will impact midlatitude weather such as cold air outbreaks on the central and east side of continents. Although there is progress in linkage research for eastern Asia, a clear gap is conformation for North America. We show two stationary temperature/geopotential height patterns where warmer Arctic temperatures have reinforced existing tropospheric jet stream wave amplitudes over North America: a Greenland/Baffin Block pattern during December 2010 and an Alaska Ridge pattern during December 2017. Even with continuing Arctic warming over the past decade, other recent eastern US winter months were less susceptible for an Arctic linkage: the jet stream was represented by either zonal flow, progressive weather systems, or unfavorable phasing of the long wave pattern. The present analysis lays the scientific controversy over the validity of linkages to the inherent intermittency of jet stream dynamics, which provides only an occasional bridge between Arctic thermodynamic forcing and extended midlatitude weather events.

Food Security and Extreme Events: Evidence from Smallholder Farmers in Central America

Science.gov (United States)

Saborio-Rodriguez, M.; Alpizar, F.; Harvey, C.; Martinez, R.; Vignola, R.; Viguera, B.; Capitan, T.

2016-12-01

Extreme weather events, which are expected to increase in magnitude and frequency due to climate change, are one of the main threats for smallholder farmers in Central America. Using a rich dataset from carefully selected subsistence farm households, we explore the determinants and severity of food insecurity resulting from extreme hydrometeorological hazards. In addition, we analyze farmerś coping strategies. Our analysis sheds light over food insecurity as an expression of vulnerability in a region that is expected to be increasingly exposed to extreme events and in a population already stressed by poverty and lack of opportunities. Regarding food insecurity, multivariate analyses indicate that education, having at least one migrant in the household, labor allocation, number of plots, and producing coffee are determinants of the probability of experiencing lack of food after an extreme weather event. Once the household is lacking food, the duration of the episode is related to access to credit, number of plots, producing coffee, ownership of land and gender of the head of the household. This results are in line with previous literature on the determinants of food insecurity in particular, and vulnerability, in general. Our dataset also allows us to analyze coping strategies. Households experiencing lack of food after an extreme weather event report mainly changes in their habits, as decreasing the amount of food consumed (54%) and modifying their diet (35%). A low proportion of household (between 10% and 15%, depending on the nature of the event) use their assets, by redirecting their savings, migrating, and selling items from the house. Asking money or food from family and friends or from an organization is reported for 4% of the households. This general results are connected to the specific coping strategies related to damages in crops, which are explored in detail. Our results indicate that there are patterns among the household experiencing lack of food

DETERMINANTS OF THE SUCCESS OF GLOBAL AND LOCAL BRANDS IN LATIN AMERICA

Directory of Open Access Journals (Sweden)

Pablo Farías

2015-08-01

Full Text Available The purpose of this paper is to address the issue of the implementation of global and local brands in Latin America by drawing on contingency theory to develop and test hypotheses relating to how product category characteristics affect the success of global and local brands in the region. Hypotheses are tested using data obtained from top brands rankings reported in five Latin American markets (Argentina, Brazil, the Caribbean and Central America, Chile and Mexico. The study design considers estimating a logistic regression on a binomial dependent variable measuring whether 475 top brands are global or local brands, with product category characteristics as independent variables. Results reveal that product categories related to subscriptions, local tastes, high-tech, and global citizenship do have an impact on the success of global and local brands in Latin America.

Southeast Asia-South America interregionalism: a complement to bilateralism

Directory of Open Access Journals (Sweden)

M. Florencia Rubiolo

2016-09-01

Full Text Available Inter-state relations between the countries of South America and Southeast Asia (SEA have blossomed in the past 15 years, arousing the interest of a growing number of academics. Their interregional relations, on the other hand, have been less well examined, due, probably, to the fact that their development remains incipient, as well as sporadic and poorly institutionalised. The starting point for this work is the premise that in the case of non-central regions this level of connection complements and works as a feedback mechanism for bilateral links and encourages State-State, State-region and region-region rapprochement. It introduces notions of South American regionalism and centres on concepts related to non-triadic interregionalism in the initiatives between South America and SEA since 1999.

Measuring vulnerability to shocks in the gas market in South America

International Nuclear Information System (INIS)

Reymond, Mathias

2012-01-01

With a strong global demand for some 30 years, natural gas is a particular challenge for countries of South and Central America since each cubic meter of natural gas that is consumed is produced in this continent. It therefore seems appropriate to consider the risk of a collision gas and its effects on the countries most dependent on gas (either as producers or as consumers). Thus, in this paper, we study the vulnerability of gas in several countries on four ratios developed by Cabalu (2010). Once calculated from empirical data, these ratios helped to determine indicators and to classify countries according to their vulnerability in the event of a gas shock (sudden rise in prices). A picture emerges which represents an indicative classification of the countries. - Highlights: ► In this paper, we study the vulnerability of gas with four indicators. ► We focus on eight countries in South America and Central. ► These indicators helped to classify countries according to their vulnerability. ► The least vulnerable country is Bolivia. ► The most vulnerable countries are Chile and Venezuela.

Genetic diversity of Plasmodium falciparum isolates from naturally infected children in north-central Nigeria using the merozoite surface protein-2 as molecular marker.

Science.gov (United States)

Oyedeji, Segun Isaac; Awobode, Henrietta Oluwatoyin; Anumudu, Chiaka; Kun, Jürgen

2013-08-01

To characterize the genetic diversity of Plasmodium falciparum (P. falciparum) field isolates in children from Lafia, North-central Nigeria, using the highly polymorphic P. falciparum merozoite surface protein 2 (MSP-2) gene as molecular marker. Three hundred and twenty children were enrolled into the study between 2005 and 2006. These included 140 children who presented with uncomplicated malaria at the Dalhatu Araf Specialist Hospital, Lafia and another 180 children from the study area with asymptomatic infection. DNA was extracted from blood spot on filter paper and MSP-2 genes were genotyped using allele-specific nested PCR in order to analyze the genetic diversity of parasite isolates. A total of 31 and 34 distinct MSP-2 alleles were identified in the asymptomatic and uncomplicated malaria groups respectively. No difference was found between the multiplicity of infection in the asymptomatic group and that of the uncomplicated malaria group (P>0.05). However, isolates of the FC27 allele type were dominant in the asymptomatic group whereas isolates of the 3D7 allele type were dominant in the uncomplicated malaria group. This study showed a high genetic diversity of P. falciparum isolates in North-central Nigeria and is comparable to reports from similar areas with high malaria transmission intensity. Copyright © 2013 Hainan Medical College. Published by Elsevier B.V. All rights reserved.

Whole-exome sequencing reveals genetic variants associated with chronic kidney disease characterized by tubulointerstitial damages in North Central Region, Sri Lanka.

Science.gov (United States)

Nanayakkara, Shanika; Senevirathna, S T M L D; Parahitiyawa, Nipuna B; Abeysekera, Tilak; Chandrajith, Rohana; Ratnatunga, Neelakanthi; Hitomi, Toshiaki; Kobayashi, Hatasu; Harada, Kouji H; Koizumi, Akio

2015-09-01

The familial clustering observed in chronic kidney disease of uncertain etiology (CKDu) characterized by tubulointerstitial damages in the North Central Region of Sri Lanka strongly suggests the involvement of genetic factors in its pathogenesis. The objective of the present study is to use whole-exome sequencing to identify the genetic variants associated with CKDu. Whole-exome sequencing of eight CKDu cases and eight controls was performed, followed by direct sequencing of candidate loci in 301 CKDu cases and 276 controls. Association study revealed rs34970857 (c.658G > A/p.V220M) located in the KCNA10 gene encoding a voltage-gated K channel as the most promising SNP with the highest odds ratio of 1.74. Four rare variants were identified in gene encoding Laminin beta2 (LAMB2) which is known to cause congenital nephrotic syndrome. Three out of four variants in LAMB2 were novel variants found exclusively in cases. Genetic investigations provide strong evidence on the presence of genetic susceptibility for CKDu. Possibility of presence of several rare variants associated with CKDu in this population is also suggested.