... type Progress Annual Report to the Nation Cancer Portfolio Snapshots Milestones in Cancer Research & Discovery Stories of ... Editorial Board Integrative Therapies Editorial Board Levels of Evidence Levels of Evidence: Treatment Levels of Evidence: Supportive & ...
... AGENCY Draft Toxicological Review of Methanol (Non-Cancer) in Support of Summary Information on the... Review of Methanol (Non-Cancer): In Support of Summary Information on the Integrated Risk Information... released an external peer review draft IRIS Toxicological Review for methanol...
The Summary Information Report (SIR) provides summary data concerning NRC and its licensees for general use by the Chairman, other Commissioners and Commission staff offices, the Executive Director for Operations, and the Office Directors. SIR is published quarterly by the Management Information Branch (49-27834) of the Office of Resource Management
The Summary Information Report (SIR) provides summary data concerning NRC and its licensees for general use by the Chairman, other Commissioners and Commission staff offices, the Executive Director for Operations, and the Office Directors. SIR is published quarterly by the Management Information Branch (49-27834) of the Office of Resource Management. This branch was formerly part of the Office of Management and Program Analysis
Siegel, S. [National Library of Medicine, Bethesda, MD (United States)
An increased level of mathematical sophistication will be needed in the future to be able to handle the spectrum of information as it comes from a broad array of biological systems and other sources. Classification will be an increasingly complex and difficult issue. Several projects that are discussed are being developed by the US Department of Health and Human Services (DHHS), including a directory of risk assessment projects and a directory of exposure information resources.
The Summary Information Report (SIR) provides summary data concerning NRC and its licensees for general use by the Chairman, other Commissioners and Commission staff offices, the Executive Director for Operations, and the Office Directors. SIR is published quarterly by the Management Information Branch (49-27834) of the Office of Resource Management
... thereby support risk management decisions designed to protect public health. II. How To Submit Comments to... addendum addressing additional studies. Description and analyses of these studies are included as an... Information Management Team (Address: Information Management Team, National Center for...
... support risk management decisions designed to protect public health. III. How To Submit Comments to the... Risk Information System (IRIS) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of a...: Information Management Team, National Center for Environmental Assessment , U.S. Environmental...
... Research Cervical Cancer Treatment (PDQ®)–Patient Version General Information About Cervical Cancer Key Points Cervical cancer is ... the NCI website . Cervical Cancer During Pregnancy General Information About Cervical Cancer During Pregnancy Treatment of cervical ...
... for information about colorectal cancer in children. Health history can affect the risk of developing colon cancer. ... through. This procedure is called a colostomy. A bag is placed around the stoma to collect the ...
... Offices Close + - Text Size Cancer Information on the Internet For many people, the Internet has become the ... Always remember that the information found on the Internet should not take the place of medical advice. ...
Harrop, J. Phil; Dean, Julie A.; Paskett, Electra D.
The number of cancer survivors and amount of cancer survivorship research has grown substantially during the past three decades. This paper provides a review of interventional and observational cancer survivorship research efforts as well as a summary of current cancer survivorship research projects being conducted by National Cancer Institute-designated cancer centers in an effort to identify areas that need further attention.
Peterson, John (Editor)
A team was formed to assess NASA Office of Space Science (OSS) information technology research and development activities. These activities were reviewed for their relevance to OSS missions, for their potential for using products better supplied by industry or other government agencies, and for recommending an IT infusion strategy for appropriate products for OSS missions. Assessment scope and methodology and the findings and recommendations of OSS IT users and providers are presented.
... Cancer Prevention Lung Cancer Screening Research Small Cell Lung Cancer Treatment (PDQ®)–Patient Version General Information About Small Cell Lung Cancer Go to Health Professional Version Key Points Small ...
An Informal Workshop on Intense Polarized Ion Sources was held on March 6, 1980, at the O'Hare Hilton Hotel, Chicago, Illinois. The purpose of the Workshop was to discuss problems in developing higher-intensity polarized proton sources, particularly the optically-pumped source recently proposed by L.W. Anderson of the University of Wisconsin. A summary of the discussions is reported
The Department of Energy (DOE) Information Architecture, Volume 2, Baseline Analysis, is a collaborative and logical next-step effort in the processes required to produce a Departmentwide information architecture. The baseline analysis serves a diverse audience of program management and technical personnel and provides an organized way to examine the Department`s existing or de facto information architecture. A companion document to Volume 1, The Foundations, it furnishes the rationale for establishing a Departmentwide information architecture. This volume, consisting of the Baseline Analysis Summary (part 1), Baseline Analysis (part 2), and Reference Data (part 3), is of interest to readers who wish to understand how the Department`s current information architecture technologies are employed. The analysis identifies how and where current technologies support business areas, programs, sites, and corporate systems.
The HSE Central Index of Dose Information (CIDI) receives annual summaries of radiation doses recorded for employees designated as classified persons under the Ionising Radiations Regulations 1985 (IRR 85). These annual summaries are required from Approved Dosimetry Services (ADS) which operate in Great Britain under IRR 85. Separate information is also sent to CIDI by an ADS whenever an employee terminates employment. Approval to make assessments of doses to classified persons and/or to keep records of such assessments is granted to suitable dosimetry services by HSE. It is a condition of approval for dose record-keeping that annual dose summaries should be sent to CIDI, thus fulfilling the statutory duty on employers under IRR 85 to make arrangements with their ADS to send such data to HSE. The most common form of dose assessment is from measurements by an external body dosemeter of the thermoluminescent (TLD) or film type but ADS may be approved for other kinds of measurement, such as bio-assay, whole or partial body monitoring for internal radionuclides and personal or static air monitoring. The resulting assessments of dose are included in dose records. (author)
Expert-reviewed information summary about the genetics of kidney cancer, including information about specific genes and family cancer syndromes. The summary also contains information about screening for kidney cancer and research aimed at prevention of this disease.
... affect prognosis (chance of recovery) and treatment options. Pancreatic cancer is a disease in which malignant (cancer) cells form in the ... the cancer cells in the liver are actually pancreatic cancer cells. The disease is metastatic pancreatic cancer, not liver cancer. The ...
... Treatment Genetics of Colorectal Cancer Age and family history can affect the risk of rectal cancer. Anything ... to flow from the body to a collection bag. After the cancer is removed, the surgeon will ...
Nandakumar, A.; Ramnath, T; Chaturvedi, Meesha
Cancer of breast has emerged as the leading site of cancer in most urban populations of India. For the year 2007, there have been an estimated 82,000 new cases of cancer Breast in India. It is rapidly replacing cancer of cervix as the most important leading site of cancer among women. The data collected over the years from five urban population based cancer registries namely Bangalore, Bhopal, Chennai, Delhi and Mumbai, under the network of National Cancer Registry Programme (NCRP) have shown...
Nandakumar, A; Ramnath, T; Chaturvedi, Meesha
Cancer of breast has emerged as the leading site of cancer in most urban populations of India. For the year 2007, there have been an estimated 82,000 new cases of cancer Breast in India. It is rapidly replacing cancer of cervix as the most important leading site of cancer among women. The data collected over the years from five urban population based cancer registries namely Bangalore, Bhopal, Chennai, Delhi and Mumbai, under the network of National Cancer Registry Programme (NCRP) have shown a statistical rising trend in the incidence rate of breast cancer. In hospital-based cancer registries, cancer of the breast is the leading site of cancer in Mumbai and Thiruvananthapuram, second leading site in Bangalore, Dibrugarh and Chennai. Cancer of breast constitutes 14.3 to 30.0% of all cancers in women in these HBCRs. The report on 'Development of an Atlas of Cancer in India' showed that Chandigarh (39.5), North Goa (36.8), Aizawl (36.2) and Panchkula (34.6) had the higher microscopic incidence rates of breast cancer compared to that seen in Delhi PBCR that had the highest rate among all PBCRs. PMID:22930611
Whynes, David K.; Clarke, Katherine; Philips, Zoe; Avis, Mark
Purpose: To identify women's sources of information about cervical cancer screening, information which women report receiving during Pap consultations, information they would like to receive, and the relationships between perceived information needs, personal characteristics and information sources. Design/methodology/approach: Logistic regression…
... enlarged thyroid). Having a family history of thyroid disease or thyroid cancer. Having certain genetic conditions such as familial medullary thyroid cancer (FMTC), multiple endocrine neoplasia type 2A ...
... are used to detect testicular cancer: Alpha-fetoprotein (AFP). Beta-human chorionic gonadotropin (β-hCG). Tumor marker ... places in the body, and blood levels of AFP, β-hCG, and LDH). Type of cancer. Size ...
... Español 1-800-4-CANCER Live Chat Publications Dictionary Menu Contact Dictionary Search About Cancer Causes and Prevention Risk Factors ... Contacts Other Funding Find NCI funding for small business innovation, technology transfer, and contracts Training Cancer Training ...
... Español 1-800-4-CANCER Live Chat Publications Dictionary Menu Contact Dictionary Search About Cancer Causes and Prevention Risk Factors ... Contacts Other Funding Find NCI funding for small business innovation, technology transfer, and contracts Training Cancer Training ...
... Español 1-800-4-CANCER Live Chat Publications Dictionary Menu Contact Dictionary Search About Cancer Causes and Prevention Risk Factors ... Contacts Other Funding Find NCI funding for small business innovation, technology transfer, and contracts Training Cancer Training ...
NCI convened a workshop of representative research teams that have been leaders in defining the genomic landscape of childhood cancers to discuss the influence of genomic discoveries on the future of childhood cancer research.
... AGENCY Draft Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the..., ``Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the Integrated Risk..., 2010. The listening session on the draft assessment for hexavalent chromium will be held on November...
... AGENCY Draft Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the..., ``Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the Integrated Risk... workshop on the draft assessment for Hexavalent Chromium will be held on May 12, 2011, beginning at 8:30...
... AGENCY Draft Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the... period on September 30, 2010 (75 FR 60454) for the external review draft human health assessment titled, ``Toxicological Review of Hexavalent Chromium: In Support of Summary Information on the Integrated...
This report transmits a summary of radiation shielding nuclear design studies performed to support the Prometheus project. Together, the enclosures and references associated with this document describe NRPCT (KAPL and Bettis) shielding nuclear design analyses done for the project
Niederdeppe, Jeff; Frosch, Dominick L; Hornik, Robert C.
The shift toward viewing patients as active consumers of health information raises questions about whether individuals respond to health news by seeking additional information. This study examines the relationship between cancer news coverage and information seeking using a national survey of adults aged 18 years and older. A Lexis-Nexis database search term was used to identify Associated Press (AP) news articles about cancer released between October 21, 2002, and April 13, 2003. We merged t...
... radiation therapy . Mohs microsurgery . A clinical trial of laser therapy . Check the list of NCI-supported cancer clinical ... nodes in the groin ). External or internal radiation therapy followed by ... clinical trial of laser surgery . Check the list of NCI-supported cancer ...
Olsen, J H; Andersen, A; Dreyer, L;
An overview is given of the most important known causes of cancer in the five Nordic countries and the resulting number of cancers that are potentially avoidable. The main causes include active and passive smoking, alcohol consumption, exposure to asbestos and other occupational carcinogens, solar...
Expert-reviewed information summary in which the features of hereditary cancer and the structure and content of other PDQ cancer genetics summaries are described. The summary also contains an extensive list of genetics resources available online.
... liquid that contains barium (a silver-white metallic compound ). The liquid coats the esophagus and stomach, and ... remove tissue samples, which are checked under a microscope for signs of cancer. When the esophagus and ...
... liquid that contains barium (a silver-white metallic compound ). The liquid coats the esophagus and stomach, and ... tissues so they can be viewed under a microscope to check for signs of cancer. A biopsy ...
... liquid that contains barium (a silver-white metallic compound ). The liquid coats the esophagus and x-rays ... tissues so they can be viewed under a microscope to check for signs of cancer. Certain factors ...
The National Center for Advanced Information Components Manufacturing focused on manufacturing research and development for flat panel displays, advanced lithography, microelectronics, and optoelectronics. This report provides an overview of the program, summaries of the technical projects, and key program accomplishments.
... The surgeon may use part of the small intestine to make a tube that passes urine through an opening ( stoma ). This is called an ostomy or urostomy . If ... surgeon may also use part of the small intestine to make a new storage pouch ( continent ... the urine through a stoma. Even if the doctor removes all the cancer ...
... around it. Sometimes lymph nodes , half of the thyroid gland on the same side of the body as the cancer, and muscles, tissues , and a nerve in the neck are also removed. Tumor debulking : A surgical procedure in which as much ...
This document contains background information for the Workshop in general and the presentation entitled 'Identification and Summary Characterization of Materials Potentially Requiring Vitrification' that was given during the first morning of the workshop. summary characteristics of 9 categories of US materials having some potential to be vitrified are given. This is followed by a 1-2 page elaborations for each of these 9 categories. References to more detailed information are included
PIO Instructions and ToolsFind instructions, forms, and templates for the management of all types of Division of Cancer Prevention clinical trials.Clinical Trials Reference MaterialsModel clinical agreements, human subject protection and informed consent models, gender and minority inclusion information, and monitoring policy and guidelines. |
Sorensen, Lena; Gavier, Maria; Hellesø, Ragnhild
The ability to access and understand health information is becoming more critical to managing one's own health and illness. Informatics tools are increasingly the central resources for responding to these needs. But just as information is culturally bound, so are the tools used to access it; both are bounded by the contexts in which they are situated. Latinas face more barriers in accessing needed information due to cultural, linguistic and health access inequities in the US. Although breast cancer rates for Latinas are lower than for non-Latina white women, they are more likely to have a more advanced stage at diagnosis and poorer quality of survivorship. Few studies have explored Latina breast cancer survivors' information needs & strategies. This community-based study focused on Mexican American women with breast cancer and explored their health information experiences, needs, and strategies; it examined their perceptions of how their relationships with providers influenced how information was accessed and utilized. Managing information was not an individual responsibility for any of these women. All of these women had access and used the Internet either directly or through their support networks. All emphasized the importance of having a select support network of people (information partners) for receiving, searching, and interpreting all health information about their illness. If information partners are strategies preferred by Latinas, then we must refocus our assessment of e-health literacy competencies on networks rather than individuals. PMID:19592948
Richard J. Bull; Antone L. Brooks
OAK-B135 A symposium discussing the implications of certain phenomena observed in radiation biology for cancer risk assessment in general. In July of 2002 a workshop was convened that explored some of the intercellular phenomena that appear to condition responses to carcinogen exposure. Effects that result from communication between cells that appear to either increase the sphere of damage or to modify the sensitivity of cells to further damage were of particular interest. Much of the discussion focused on the effects of ionizing radiation that were transmitted from cells directly hit to cells not receiving direct exposure to radiation (bystander cells). In cell culture, increased rates of mutation, chromosomal aberration, apoptosis, genomic instability, and decreased clonogenic survival have all been observed in cells that have experienced no direct radiation. In addition, there is evidence that low doses of radiation or certain chemicals give rise to adaptive responses in which the treated cells develop resistance to the effects of high doses given in subsequent exposures. Data were presented at the workshop indicating that low dose exposure of animals to radiation and some chemicals frequently reduces the spontaneous rate of mutation in vitro and tumor responses in vivo. Finally, it was concluded that considerable improvement in understanding of how genetic variation may modify the impact of these phenomena is necessary before the risk implications can be fully appreciated. The workshop participants discussed the substantive challenge that these data present with respect to simple linear methodologies that are currently used in cancer risk assessment and attempted to identify broad strategies by which these phenomena may start to be used to refine cancer risk assessment methods in the future.
Contact InformationCapital Consulting Corporation is providing logistical support for this meeting. If you have questions or need assistance, please call Jennifer Adona at (301) 468-6073, or e-mail her at firstname.lastname@example.org. |
Kowitz, Albert C.; Clark, Richard E.
A description was sought of the types of sources of information about marijuana used by 300 middle class fifth, seventh, and eleventh grade students. During individual meetings with experienced female interviewers, students were asked to relate sources which were most influential in providing information about marihuana at the following stages:…
... science-based human health assessments to support the Agency's regulatory activities. The IRIS database... AGENCY Draft Toxicological Review of Dichloromethane: In Support of Summary Information on the Integrated Risk Information System (IRIS) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of...
... science-based human health assessments to support the Agency's regulatory activities. The IRIS database... AGENCY Draft Toxicological Review of Hexachloroethane: In Support of the Summary Information in the Integrated Risk Information System (IRIS) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice...
The Solid Waste Information Management System (SWIMS) is a Department of Energy information system for radioactive solid waste. This document is a summary of the CY 1986 data and the forecasted data for CY 1987 reported by DOE sites. Detailed data are included in the appendices
Document available in abstract form only. Full text follows: During the five sessions of the workshop, much insight has been gained in a variety of issues and challenges that national programmes will encounter as they approach the construction phase of deep geologic repositories as well as their plans to address and resolve these issues. Due to the wide range of participating programmes and due to the different phases of repository development represented, the information presented at the workshop ranged from general and generic questions to specific technical, managerial, administrative, legal, regulatory and procedural issues. Although many issues still awaiting their resolutions, it can be observed that there were joint views amongst the participants with respect to the nature and specificities of these issues. These include: - the need for flexibility (within a so-called safety envelope) when projects evolve over time, - the need to address targets could be very difficult in nature and in some cases may compete with each other when developing and optimising repository systems, - the central role of management with regard to developing adequate professional attitudes and an appropriate safety culture, taking into account the various professional disciplines involved, - the need for integrating different legal and regulatory fields, often addressed by different authorities, and the question of a 'leading regulator'; - the technical challenge of conceptualising parallel processes such as excavation in parts of a repository and emplacement in others and the need to fulfil related safety requirements (mining and occupational, radiation protection etc.), - monitoring may have different roles in different phases of repository development, or - the outstanding role of the safety case prepared in advance to operation (waste emplacement) compared to the cases prepared at other stages of repository development, and the need to act accordingly in the regulatory
... Prevention Lung Cancer Screening Research Non-Small Cell Lung Cancer Treatment (PDQ®)–Patient Version General Information About Non-Small Cell Lung Cancer Go to Health Professional Version Key Points Non- ...
Mathur, Samir D
The black hole information paradox is one of the most important issues in theoretical physics. We review some recent progress using string theory in understanding the nature of black hole microstates. For all cases where these microstates have been constructed, one finds that they are horizon sized `fuzzballs'. Most computations are for extremal states, but recently one has been able to study a special family of non-extremal microstates, and see `information carrying radiation' emerge from these gravity solutions. We discuss how the fuzzball picture can resolve the information paradox. We use the nature of fuzzball states to make some conjectures on the dynamical aspects of black holes, observing that the large phase space of fuzzball solutions can make the black hole more `quantum' than assumed in traditional treatments.
Six reports concerning design of an information system to aid the Los Angeles city schools in implementing accountability and program budgeting are summarized. Extensive interviewing and system analysis led to focusing decisionmaking and accountability on the individual school principal, unlike the present centralized decisionmaking and resource…
2004 ITACS Customer Satisfaction Survey Report The IT Strategic Plan, The Information Revolution: Planning for Institutional Change, proposed a number of recommendations to improve management, customer responsiveness, and accountability for the IT arena at NPS. A periodic customer satisfaction survey was included as one of those recommendations.
Tatem, H.E.; Brandon, D.L.; Lee, C.R.; Simmers, J.W.; Skogerboe, J.G.
The Water Quality Act of 1987, Section 118, authorizes the Great Lakes National Program Office (GLNPO) to carry out a 5-year study and demonstration project, Assessment and Remediation of Contaminated Sediments (ARCS), with emphasis on the removal of toxic pollutants from bottom sediments. Information from the ARCS program is to be used to guide the development of Remedial Action Plans (RAPs) for 42 identified Great Lakes Areas of Concern (AOCs) as well as Lake-wide Management Plans. The AOCs are areas where serious impairment of beneficial uses of water or biota (drinking, swimming, fishing, navigation, etc.) is known to exist, or where environmental quality criteria are exceeded to the point that such impairment is likely. Priority consideration was given to the following AOCs: Saginaw Bay, Michigan; Sheboygan Harbor, Wisconsin; Grand Calumet River, Indiana; Ashtabula River, Ohio; and Buffalo River, New York. This report summarizes the information obtained for the Ashtabula River AOC. (GLNPO Subject-Reference Matrix). Data and information from numerous reports have been included as figures and tables; wherever possible, the reference sources are identified.
... following PDQ summaries: Ovarian Germ Cell Tumors Treatment Testicular Cancer Treatment Age and gender can affect the risk ... summaries of the latest published information on cancer prevention, detection, genetics, treatment, supportive care, and complementary and ...
... AGENCY Draft Toxicological Review of Urea: In Support of Summary Information on the Integrated Risk... Urea: In Support of Summary Information on the Integrated Risk Information System (IRIS)'' [EPA/ 635/R..., 2010. The listening session on the draft assessment for urea will be held on November 16,...
... Information (RFI): Opportunities To Apply a Department of Health and Human Services Message Library To Advance... Administration, HHS. ACTION: Summary of Responses to Request for Information (RFI). SUMMARY: On January 29, 2013, the Health Resources and Services Administration (HRSA) issued a Request for Information (RFI)...
Ferrocyanide wastes were generated at the Hanford site during the mid to late 1950s to make more tank space available for the storage of high level nuclear waste. The ferrocyanide process was developed as a method of removing 137Cs from existing waste solutions and from process solutions that resulted from the recovery of valuable uranium in waste tanks. During the coarse of the research associated with the ferrocyanide process, it was discovered that ferrocyanide materials when mixed with NaNO3 and/or NaNO2 exploded. This chemical reactivity became an issue in the 1980s when the safety associated with the storage of ferrocyanide wastes in Hanford tanks became prominent. These safety issues heightened in the late 1980s and led to the current scrutiny of the safety associated with these wastes and the current research and waste management programs. Over the past three years, numerous explosive test have been carried out using milligram quantities of cyanide compounds. These tests provide information on the nature of possible tank reactions. On heating a mixture of ferrocyanide and nitrate or nitrite, an explosive reaction normally begins at about 240 degrees C, but may occur well below 200 degrees C in the presence of catalysts or organic compounds that may act as initiators. The energy released is highly dependent on the course of the reaction. Three attempts to model hot spots in local areas of the tanks indicate a very low probability of having a hot spot large enough and hot enough to be of concern. The main purpose of this document is to inform the members of the Tank Waste Science Panel of the background and issues associated with the ferrocyanide wastes. Hopefully, this document fulfills similar needs outside of the framework of the Tank Waste Science Panel. 50 refs., 9 figs., 7 tabs
Objective: Knowledge, information and communication, within oncology, are a core clinical strength for the out-come of the disease and inadequate communication, can cause distress for the patient and their families. Design: A senior doctor conducted this study by filling in the performa after interviewing the subject of the study. Place and duration of study: This study was done in Oncology Department of Service Hospital, Lahore and was completed in four months. Subjects and Method: One hundred cancer patients were interviewed regarding their knowledge about their disease, its causes, prognosis, and information supplied by the health-care providers. They were also asked about their satisfaction regarding this information, deficiencies and pitfalls in this information, need for more information, which should supply the information from among the hospital team or their relative, attitude of the family and their communication regarding the disease. Results: Study revealed that the knowledge about the disease and its causes was present in 53% and 7% respectively. The patients (59%) wanted more information. Majority perceived that the information was not adequate and needed more information and 68% thought that more information would reduce their anxiety. The attitude of family was found encouraging in 87% of patients and 42% were communicating with other family members regarding their diseases. Conclusion: Knowledge about the disease and its cause should be increasingly supplied by the doctors, as it will reduce the anxiety and have a good effect on health. Communication among the family members needs to be improved. (author)
Wigfall, Lisa T; Friedman, Daniela B
Cancer is a leading cause of death among adults in the United States. Only 54% of U.S. adults reported seeking cancer information in 2014. Cancer information seeking has been positively associated with cancer-related health outcomes such as screening adherence. We conducted a scoping review of studies that used data from the Health Information National Trends Survey (HINTS) in order to examine cancer information seeking in depth and the relationship between cancer information seeking and cancer-related health outcomes. We searched five databases and the HINTS website. The search yielded a total of 274 article titles. After review of 114 de-duplicated titles, 66 abstracts, and 50 articles, 22 studies met inclusion criteria. Cancer information seeking was the outcome in only four studies. The other 18 studies focused on a cancer-related health outcome. Cancer beliefs, health knowledge, and information seeking experience were positive predictors of cancer information seeking. Cancer-related awareness, knowledge, beliefs, preventive behaviors, and screening adherence were higher among cancer information seekers. Results from this review can inform other research study designs and primary data collection focused on specific cancer sites or aimed at populations not represented or underrepresented in the HINTS data (e.g., minority populations, those with lower socioeconomic status). PMID:27466828
Expert-reviewed information summary about the difficult emotional responses many cancer patients experience. This summary focuses on normal adjustment issues, psychosocial distress, and adjustment disorders.
Tonn, B.E.; Oliver, C.E.
The National Information Infrastructure (NII) Education Forum was held on October 6-8, 1993, in Arlington, Virginia. The Forum was sponsored by the Office of Scientific Computing, U.S. Department of Energy (DOE). Its purpose was to discuss technology for K-12 education and what role DOE and its national laboratories could play in developing, disseminating, and using technology for K-12. The Forum brought together over 120 people from across the nation. Participants represented six groups: national laboratories; education research institutions; K-12 teachers and administrators; industry; federal agencies; and other institutions. The Forum consisted of a series of structured presentations from each of these six groups; technology demonstrations; and open, small group discussions. The presentations covered the following: important K-12 education and computing issues, national laboratory capabilities, other federal sector initiatives, and industry perspectives. The demonstration room had over 20 computers networked to the Internet. Workshop participants were shown (1) how to use the Internet to access resources anywhere in the world, (2) state-of-the-art network video teleconferencing technology, (3) multi-media technology, and (4) various other educational software systems.
This report summarizes the investigations on instrumentation and electrical systems that were subjected to a loss-of-coolant accident environment during and following the accident at Three Mile Island Unit-2 (TMI-2) on March 28, 1979. The report is a summary of information previously published in GEND-INF reports, plus current knowledge of the investigators
This executive summary describes highlights from the report, "Building Management Information Systems to Coordinate Citywide Afterschool Programs: A Toolkit for Cities." City-led efforts to build coordinated systems of afterschool programming are an important strategy for improving the health, safety and academic preparedness of children and…
... AGENCY Workshop: Cumulative Mixtures Risk of Six Selected Phthalates in Support of Summary Information on...: Notice of Peer Consultation Workshop on the Cumulative Mixtures Risk of Six Selected Phthalates; Request... phthalates as set forth in the National Academies of Science (NAS) report ``Phthalates and Cumulative...
The National Center for Advanced Information Components Manufacturing focused on manufacturing research and development for flat panel displays, advanced lithography, microelectronics, and optoelectronics. This report provides an overview of the program, program history, summaries of the technical projects, and key program accomplishments.
This page lists cancer drugs approved by the Food and Drug Administration (FDA) for bone cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.
This page lists cancer drugs approved by the Food and Drug Administration (FDA) to prevent vaginal cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.
This page lists cancer drugs approved by the Food and Drug Administration (FDA) for penile cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.
This page lists cancer drugs approved by the Food and Drug Administration (FDA) for vulvar cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.
This page lists cancer drugs approved by the Food and Drug Administration (FDA) for esophageal cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.
This page lists cancer drugs approved by the Food and Drug Administration (FDA) for endometrial cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.
This page lists cancer drugs approved by the Food and Drug Administration (FDA) for liver cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.
Expert-reviewed information summary in which cancer risk perception, risk communication, and risk counseling are discussed. The summary also contains information about recording and analyzing a family history of cancer and factors to consider when offering genetic testing.
Expert-reviewed information summary about the genetics of prostate cancer, including information about specific genes and family cancer syndromes. The summary also contains information about screening for prostate cancer and research aimed at prevention of this disease. Psychosocial issues associated with genetic testing and counseling of individuals who may have hereditary prostate cancer syndrome are also discussed.
Expert-reviewed information summary about the genetics of colorectal cancer, including information about specific genes and family cancer syndromes. The summary also contains information about screening for colorectal cancer and research aimed at prevention of this disease. Psychosocial issues associated with genetic testing and counseling of individuals who may have hereditary colorectal cancer syndrome are also discussed.
Rodrigues J-M; De Laroche G; Martin C.; Quantin C; Trombert-Paviot B
In anticipation of the creation of a cancer institute (ICL) in Saint-Etienne, France, 3 hospitals tested a procedure which permanently links hospital discharge summaries to DRG’s (PMSI). To this end used the asymmetric hashing and encrypting software developed by one of the authors which had been evaluated from 1996 to 1999 by selecting discharge summaries from each institution containing at least one malignant tumour ICD code. Thus, we were able to compile an anonymous 16,000 patient regist...
Bottorff, Joan L.; Ratner, Pamela A.; Johnson, Joy L.; Lovato, Chris Y.; Joab, S. Amanda
Accurate and sensitive communication of cancer-risk information is important. Based on a literature review of 75 research reports, expert opinion papers, and clinical protocols, a synthesis of what is known about the communication of cancer-risk information is presented. Relevance of information to those not tested is discussed. (Author/EMK)
The Solid Waste Information Management System (SWIMS) is a Department of Energy (DOE) information system for radioactive solid waste. This document is a summary of the FY 1982 data and the forecast data for FY 1983 reported by DOE sites. Detailed data are included in the appendices. The SWIMS data base contains data on the solid transuranic and solid low-level waste generated, buried, or stored at DOE sites. The burial and storage data include the period from site initiation through FY 1982
... AGENCY Draft Toxicological Review of Urea: In Support of Summary Information on the Integrated Risk... the draft human health assessment titled, ``Toxicological Review of Urea: In Support of Summary... workshop on the draft assessment for Urea will be held via teleconference on December 13, 2010,...
This page lists cancer drugs approved by the Food and Drug Administration (FDA) for head and neck cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.
Finney Rutten, Lila J; Agunwamba, Amenah A; Wilson, Patrick; Chawla, Neetu; Vieux, Sana; Blanch-Hartigan, Danielle; Arora, Neeraj K; Blake, Kelly; Hesse, Bradford W
The demonstrated benefits of information seeking for cancer patients, coupled with increases in information availability, underscore the importance of monitoring patient information seeking experiences over time. We compared information seeking among cancer survivors to those with a family history of cancer and those with no history of cancer. We identified characteristics associated with greater information seeking among cancer survivors, key sources of cancer-related information, and changes in information source use over time. Data from five iterations of the Health Information National Trends Survey (HINTS) spanning 2003 to 2013 were merged and analyzed. Frequencies, cross-tabulations, multivariate logistic regression, and multinomial regression analyses were conducted. All data were weighted to provide representative estimates of the adult US population. Cancer information seeking was reported most frequently by cancer survivors (69.8 %). The percentage of cancer survivors who reported information seeking increased from 66.8 % in 2003 to 80.8 % in 2013. Cancer information seeking was independently associated with age, education, and income; seeking was less likely among older adults, those with less education, and those with lower incomes. Compared to respondents in 2003, those in 2005 (odds ratio (OR) = 0.40, 95 % confidence interval (CI) = 0.24-0.65) and 2008 (OR = .43, 95 % CI = 0.26-0.70) were about half as likely to use the Internet as the first source of cancer information compared to a healthcare provider. Despite overall increases in cancer information seeking and access to health information from a variety of sources, healthcare providers remain a key source of health information for cancer survivors. PMID:25712202
Ross, Lone; Petersen, Morten Aagaard; Johnsen, Anna Thit; Lundstrøm, Louise Hyldborg; Grønvold, Mogens
To validate five items (CPWQ-inf) regarding satisfaction with information provided to cancer patients from health care staff, assess the prevalence of dissatisfaction with this information, and identify factors predicting dissatisfaction.......To validate five items (CPWQ-inf) regarding satisfaction with information provided to cancer patients from health care staff, assess the prevalence of dissatisfaction with this information, and identify factors predicting dissatisfaction....
... lowest in the Southwest. For cancers of the breast and cervix, American Indian/Alaska Native women are less likely than white women to have their cancer found early. References 1 National Cancer Institute. Health Disparities Defined. Rockville, MD: U.S. Department of Health and ...
The Solid Waste Information Management System (SWIMS) maintains computerized records on a master data base. It provides a comprehensive system for cataloging and assembling data into output reports. The system summarizes the solid radioactive waste generation, disposal, and storage information throughout the Department of Energy (DOE). The SWIMS data base contains the information on the transuranic (TRU) and Low-Level Waste (LLW) generated, buried, or stored by DOE facilities. The generation data covers the period from the FY 1976 transition quarter through FY 1979. The burial and storage data includes the period from site initiation through FY 1979. This document includes the DOE Summary Reports from the SWIMS, presenting the FY 1979 data and the FY 1980 forecasts. Each report is detailed by nuclide category. The categorization allows the user to separate TRU data from LLW data, etc
Kobayashi, Lindsay C.; Smith, Samuel G.
Information seeking is an important behavior for cancer prevention and control, but inequalities in the communication of information about the disease persist. Conceptual models have suggested that low health literacy is a barrier to information seeking, and that fatalistic beliefs about cancer may be a mediator of this relationship. Cancer…
Expert-reviewed information summary about the genetics of skin cancer — basal cell carcinoma, squamous cell carcinoma, and melanoma — including information about specific gene mutations and related cancer syndromes. The summary also contains information about interventions that may influence the risk of developing skin cancer in individuals who may be genetically susceptible to these syndromes.
Lee, Chul-joo; Ramirez, Susana; Lewis, Nehama; Gray, Stacy W.; Hornik, Robert C.
The gap in cancer information seeking between high-socioeconomic status (SES) cancer patients and low-SES cancer patients deserves serious attention considering the importance of information and knowledge in cancer control. We thus explored the association of SES, as measured by education, with cancer patients’ overall cancer information seeking, and with seeking from each source (i.e., the Internet, mass media, medical sources, and non-medical interpersonal sources) and across two topic categories (i.e., treatment, quality of life). We then asked whether the effect of education on treatment information seeking is reduced among those who are particularly motivated to control treatment choices. We conducted a survey with breast, prostate, and colon cancer patients diagnosed in 2005 (N = 2,013), who were randomly drawn from the Pennsylvania Cancer Registry in the fall of 2006. We found that education was more strongly associated with Internet use than with the use of other sources regardless of topics. Also, when information was sought from mass media, education had a greater association with treatment information seeking than with quality-of-life information seeking. Preference for active participation in treatment decision making, however, did not moderate the effect of education on treatment information seeking. The implications of these findings for public health research and cancer patient education were discussed. PMID:22356137
Zogorski, John S.; Zogorski, E.M.; McKallip, T.E.
This report provides a compilation of water quality information for the Rapid Creek basin in western South Dakota. Two types of information are included: First, past and current water quality monitoring data collected by the South Dakota Department of Water and Natural Resources, U.S. Forest Service, U.S. Geological Survey, and others are described. Second, a summary is included for all past water quality reports, publications, and theses that could be located during this study. A total of 62 documents were abstracted and included journal articles, abstracts, Federal agency reports and publications, university and State agency reports, local agency reports, and graduate theses. The report should be valuable to water resources managers, regulators, and others contemplating water quality research, monitoring, and regulatory programs in the Rapid Creek basin. (USGS)
The cancer registry profession has grown dramatically since its inception in 1926. Certified tumor registrars (CTRs) have become an integral part of the cancer care team by providing quality cancer data for research, statistical purposes, public health, and cancer control. In addition, CTRs have been found to be valuable in other cancer and health-related fields. Based on the need for high-quality, accurate data, the National Cancer Registrars Association (NCRA), the certification body for CTRs, has increased the educational requirement for eligibility for the CTR certification exam. This has resulted in fewer individuals who are able to meet the requirements for CTR certification. In addition, the existing cancer registry workforce is, on average, older than other allied health professions, and therefore will face an increasing number of retirements in the next few years. The high demand for CTRs, the decreased pool of CTR-eligible applicants, and the aging cancer registry workforce has resulted in an existing shortage that will only get worse as the population ages and the incidence of cancer increases. Health information management (HIM) students are well suited to pursuing further training in the cancer registry field and gaining the CTR credential. HIM students or new graduates have the needed skill set and education to pursue a cancer registry career. There are many avenues HIM educational programs can take to encourage students to pursue CTR certification and a cancer registry career. Including cancer registry functions in courses throughout the HIM curriculum, bringing in cancer registry speakers, encouraging networking, and promoting the cancer registry field and profession in general are just a few of the methods that HIM programs can use to raise awareness of and promote a cancer registry career to their students. Illinois State University has used these methods and has found them to be successful in encouraging a percentage of their graduates to pursue
Bylund, Carma L.; D'Agostino, Thomas A.; Ostroff, Jamie; Heerdt, Alexandra; Li, Yuelin; Dickler, Maura
Purpose: Previous studies have reported a significant number of patients with breast cancer seek cancer-related information from the Internet. Most studies have asked whether a patient has ever read Internet information since her diagnosis. The purpose of this study was to assess the frequency with which patients with breast cancer come to physician appointments having recently read and intending to discuss cancer-related information from the Internet. Patients and Methods: We asked 558 patients with breast cancer who were waiting to see their physicians about their experiences reading cancer-related information from the Internet and their intent to discuss the information in their current visit. Results: Fifteen percent reported reading cancer-related Internet information in the past month. Patients who had read such information in the past month were younger, had been diagnosed more recently, and were more likely to be attending a new visit. Of those who had read in the past month, 45% reported intending to discuss what they had read with their physician. Nineteen percent of patients reported having ever read breast cancer–related Internet information since their diagnosis. Conclusion: The proportion of patients with breast cancer planning to discuss Internet information during their current physician visit was relatively small. Few characteristics were associated with recent Internet use or intent to discuss. PMID:22548010
... This may lead to liver cancer. Blood banks test all donated blood for hepatitis B, which greatly lowers the risk of getting the ... This may lead to liver cancer. Blood banks test all donated blood for hepatitis C, which ... infected with hepatitis B. It is caused by hepatitis D virus (HDV) ...
Full Text Available In daily life, more and more people rely on medical websites to seek medical information and treatment methods. In order to meet the demand of users, especially, before the construction of the websites, information and function need have to he understood first. Accordingly, this research intends to investigate and analyse people's information needs in cancer prevention and treatment. This research applies in-depth interview, focus group, questionnaire and survey research methods, and analyses existing health and cancer websites to get rich materials. The results show people's cancer information need, and the priority of those needs. Finally, the author discusses the needs of provision of folk treatment information in the cancer websites.
Yalçin, Abdussamed; SILAY, KAMİLE; BÜYÜKÇELİK, Abdullah; IŞIKDOĞAN, ABDURRAHMAN; TÜRK, HACI MEHMET; Coşkun, Hasan Şenol; ÖZDEMİR, FEYYAZ; UĞURLU, Mehmet; Üstü, Yusuf; YALÇIN, Bülent
Background/aim: An opinion survey was conducted to investigate the opinions and attitudes of the Turkish population regarding cancer if they or one of their family members were to receive a diagnosis of cancer. Materials and methods: The opinion survey was completed by 6566 subjects and consisted of questions about the demographics of the participants and their overall opinions about cancer. The other points of the investigation asked whether they would inform relatives who had cancer about...
Ådland, Marit Kristine; Lykke, Marianne
Purpose: The purpose of this paper is to explore whether and how social tagging can be useful in an information website for cancer patients and their relatives. Methodology/approach: Three studies have been carried out in order to investigate the research questions. Firstly, we reviewed and...... analyzed literature about cancer patients’ information needs and seeking behavior, and about social tagging and patient terminology. Secondly, we analyzed tags applied to blog postings at Blogomkraeft.dk, a blog site at the Danish information web site Cancer.dk. The tags were compared with the formal...... browsing structure of Cancer.dk. Results from the two studies were used to develop a prototype for social tagging at Cancer.dk. Thus thirdly, we evaluated the prototype in a usability study. Findings: We found that tags have the potential to describe and provide access to web site content from the users...
Full Text Available Background: Cervical cancer is the third most common cancer worldwide. Accurate information about cervical cancer to general public can lower the burden of the disease including its mortality. Aims: We aimed to look at the quality of information available in YouTube for cervical cancer. Materials and Methods: We searched YouTube (http://www.youtube.com for videos using the keyword "Cervical cancer" on November 12, 2015. Videos were then analyzed for their source and content of information. Results: We studied 172 videos using the keyword "Cervical cancer" on November 12, 2015. We found that there were videos describing the personal stories, risk factors, and the importance of screening. However, videos discussing all the aspects of cancers were lacking. Likewise, videos from the reputed organization were also lacking. Conclusion: Although there were numerous videos available in cervical cancer, videos from reputed organizations including Center for Disease Control and Prevention, American Cancer Society, and World Health Organization were lacking. We strongly believe that quality videos from such organizations via YouTube can help lower the burden of disease.
S.L. Knijnenburg; L.C. Kremer; C. Bos; K.I. Braam; M.W.M. Jaspers
Background. Knowledge about past disease, treatment, and possible late effects has previously been shown to be low in survivors of childhood cancer and their relatives. This study investigated the information needs of childhood cancer survivors and their parents and explored possible determinants fo
... exposure, high levels of estrogen, and a family history of breast cancer can increase a man’s risk ... also show the dimpled appearance called peau d’orange (like the skin of an orange). There may ...
... β-hCG) or a protein called alpha-fetoprotein (AFP). Other cancers and certain noncancer conditions, including cirrhosis and hepatitis , can also increase AFP levels. Complete blood count (CBC) : A procedure in ...
Kobayashi, Lindsay C; Smith, Samuel G
Information seeking is an important behavior for cancer prevention and control, but inequalities in the communication of information about the disease persist. Conceptual models have suggested that low health literacy is a barrier to information seeking, and that fatalistic beliefs about cancer may be a mediator of this relationship. Cancer fatalism can be described as deterministic thoughts about the external causes of the disease, the inability to prevent it, and the inevitability of death at diagnosis. This study aimed to examine the associations between these constructs and sociodemographic factors, and test a mediation model using the American population-representative Health Information and National Trends Survey (HINTS 4), Cycle 3 (n = 2,657). Approximately one third (34%) of the population failed to answer 2/4 health literacy items correctly (limited health literacy). Many participants agreed with the fatalistic beliefs that it seems like everything causes cancer (66%), that one cannot do much to lower his or her chances of getting cancer (29%), and that thinking about cancer makes one automatically think about death (58%). More than half of the population had "ever" sought information about cancer (53%). In analyses adjusted for sociodemographic characteristics and family cancer history, people with limited health literacy were less likely to have ever sought cancer information (odds ratio [OR] = 0.63; 0.42-0.95) and more frequently endorsed the belief that "there's not much you can do . . ." (OR = 1.61; 1.05-2.47). This fatalistic belief partially explained the relationship between health literacy and information seeking in the mediation model (14% mediation). Interventions are needed to address low health literacy and cancer fatalism to increase public interest in cancer-related information. PMID:26377524
Full Text Available In anticipation of the creation of a cancer institute (ICL in Saint-Etienne, France, 3 hospitals tested a procedure which permanently links hospital discharge summaries to DRG’s (PMSI. To this end used the asymmetric hashing and encrypting software developed by one of the authors which had been evaluated from 1996 to 1999 by selecting discharge summaries from each institution containing at least one malignant tumour ICD code. Thus, we were able to compile an anonymous 16,000 patient register. 5 tumour locations were found in almost half the patients: breast (16.7 %, bowel (9.6 %, lung and bronchi (9.1 %, prostate gland (6.8 %, and skin (5.5 %. We estimate that the future ICL will take care of 2,500 cancer patients annually. We compared the number of new patients hospitalized each year (1,500 to the incidence reported by the manual cancer registers (FRANCIM. We conclude that this linking procedure is both feasible and acceptable when its precise health goal is clearly defined. Following this initial step, we are extending the procedure to involve other health care institutions (both public and private in the Saint Etienne area and to the main regional cancer network (ONCORA. Beginning in 2001 the French ministry of health has approved this DRGs linking procedure throughout France.
Boudreault, Patrick; Palmer, Christina
Information about cancer, the disease that kills more Americans than any other except heart disease, is essential. In some ways, information is our first line of defense. It allows us to identify individual risk factors, to note when a problem means we should see a professional, and to avoid activities that might put us at risk. However,…
... Cancer? Breast Cancer Colon/Rectum Cancer Lung Cancer Prostate Cancer Skin Cancer Show All Cancer Types News and Features Cancer Glossary ACS Bookstore Cancer Information Cancer Basics Cancer Prevention & Detection Signs & Symptoms of Cancer Treatments & Side Effects ...
Monaco, Valerie; Krills, Sandra K.
The objective of this study was to examine the information provided on comprehensive cancer centers’ Web sites regarding clinical trials. Thirty-nine Web sites were visually inspected for four categories of variables: navigation to the clinical trial information, search functionality provided to the visitor, information content provided about trials, and the reading level of the information provided. Results indicated that for those Web sites that provided information about clinical trials, t...
Full Text Available Abstract Background High-quality cancer information resources are available but underutilized by the public. Despite greater awareness of the National Cancer Institute's Cancer Information Service among low-income African Americans and Hispanics compared with Caucasians, actual Cancer Information Service usage is lower than expected, paralleling excess cancer-related morbidity and mortality for these subgroups. The proposed research examines how to connect the Cancer Information Service to low-income African-American and Hispanic women and their health care providers. The study will examine whether targeted physician mailing to women scheduled for colposcopy to follow up an abnormal Pap test can increase calls to the Cancer Information Service, enhance appropriate medical follow-up, and improve satisfaction with provider-patient communication. Methods/Design The study will be conducted in two clinics in ethnically diverse low-income communities in Chicago. During the formative phase, patients and providers will provide input regarding materials planned for use in the experimental phase of the study. The experimental phase will use a two-group prospective randomized controlled trial design. African American and Hispanic women with an abnormal Pap test will be randomized to Usual Care (routine colposcopy reminder letter or Intervention (reminder plus provider recommendation to call the Cancer Information Service and sample questions to ask. Primary outcomes will be: 1 calls to the Cancer Information Service; 2 timely medical follow-up, operationalized by whether the patient keeps her colposcopy appointment within six months of the abnormal Pap; and 3 patient satisfaction with provider-patient communication at follow-up. Discussion The study examines the effectiveness of a feasible, sustainable, and culturally sensitive strategy to increase awareness and use of the Cancer Information Service among an underserved population. The goal of linking a
McCallie, Ellen; Bell, Larry; Lohwater, Tiffany; Falk, John H.; Lehr, Jane L.; Lewenstein, Bruce V.; Needham, Cynthia; Wiehe, Ben
Science and technology are embedded in every aspect of modern life. This executive summary describes how Public Engagement with Science (PES), in the context of informal science education (ISE), can provide opportunities for public awareness of and participation in science and technology. PES is an approach that has developed in the last 10 years…
Expert-reviewed information summary about the genetics of breast and gynecologic cancers, including information about specific genes and family cancer syndromes. The summary also contains information about interventions that may influence the risk of developing breast and gynecologic cancers in individuals who may be genetically susceptible to these diseases. Psychosocial issues associated with genetic testing are also discussed.
Schafer, D.M.; Glowka, D.A.; Teufel, L.W.
Russian scientists and engineers have drilled the deepest holes in the world. It is recognized that this experience has given them an expertise in drilling superdeep holes, as well as other aspects of drilling, completions, and geophysics. More and more US oil and gas companies are vigorously expanding their exploration and development into Russia. It is important for them to identify and use Russian technology in drilling, completion, logging, and reservoir characterization to the extent possible, in order to both reduce drilling costs and help support the Russian economy. While these US companies are interested in becoming involved in and/or sponsoring research in Russia, they have been unsure as to which scientists and institutes are working on problems of interest. It was also important to determine in which areas Russian technology is farther advanced than in the West. Such technology could then be commercialized as part of the Industrial Partnering Program. In order to develop a clear understanding of these issues, two Sandia engineers with drilling and completions expertise and a geophysicist with expertise in reservoir analysis traveled to Russia to meet with Russian scientists and engineers to discuss their technologies and areas of interest. This report contains a summary of the information obtained during the visit.
U.S. Department of Health & Human Services — Nursing home summary information for the Health and Fire Safety Inspections currently listed on Nursing Home Compare, including dates of the three most recent...
This program summary describes each of the DOE's Biomass Energy System's projects funded or in existence during fiscal year 1979 and reflects their status as of September 30, 1979. The summary provides an overview of the ongoing research, development, and demonstration efforts of the preceding fiscal year as well. (DMC)
Expert-reviewed information summary about the challenges faced by family caregivers of cancer patients. This summary focuses on typical caregiver roles and concerns, and helpful interventions for caregivers.
Andriana Barisic; Gord Glendon; Nayana Weerasooriya; Andrulis, Irene L.; Knight, Julia A.
Obtaining complete medical record information can be challenging and expensive in breast cancer studies. The current literature is limited with respect to the accuracy of self-report and factors that may influence this. We assessed the agreement between self-reported and medical record breast cancer information among women from the Ontario site of the Breast Cancer Family Registry. Women aged 20–69 years diagnosed with incident breast cancer 1996–1998 were identified from the Ontario Cancer R...
Kloda, Lorie A; Koufogiannakis, Denise; Mallan, Katrine
Objective: Library instruction can and should be informed by research, and current research should inform librarians’ instructional practices. In order to maximize the impact of research, the journal Evidence Based Library and Information Practice (EBLIP) publishes evidence summaries - synopses and critical appraisals of published research which facilitate knowledge translation in library and information practice. Each evidence summary consists of a structured abstract describing the objectiv...
Nghiem, A Z; Mahmoud, Y; Som, R
The internet is frequently used by patients for researching information regarding breast cancer. This study aims to assess the quality of these websites using validated tools. The term 'breast cancer' was searched for in 3 search engines. The top 20 results were selected, and duplicates and irrelevant websites were excluded. 26/34 websites were analysed using the DISCERN Plus tool, HONcode and the JAMA benchmarks. 46% of the websites were classed as 'excellent' when assessed with the DISCERN tool. The range of DISCERN scores was wide (range: 25-74). Nine websites were found to be HONcode certified. Seven websites complied with all four JAMA benchmarks. This study shows the quality of breast cancer information on the internet is on the whole good; however the range of quality is wide. We recommend healthcare professionals use all 3 tools together to establish which websites are best to advise which websites patients should trust. PMID:26547835
Bottorff, Joan L.; McKeown, Stephanie Barclay; Carey, Joanne; Haines, Rebecca; Okoli, Chizimuzo; Johnson, Kenneth C.; Easley, Julie; Ferrence, Roberta; Baillie, Lynne; Ptolemy, Erin
Current evidence confirms that young women who smoke or who have regular long-term exposure to secondhand smoke (SHS) have an increased risk of developing premenopausal breast cancer. The aim of this research was to examine the responses of young women to health information about the links between active smoking and SHS exposure and breast cancer…
Van Houtven, Courtney Harold; Ramsey, Scott D; Hornbrook, Mark C.; Atienza, Audie A.; van Ryn, Michelle
This study quantified the economic burden for informal caregivers of lung cancer and colorectal cancer patients, by cancer type, phase of disease, stage at diagnosis, patient age, and relationship, and found this burden to be substantial.
Full Text Available Abstract Background Extraction of clinical information such as medications or problems from clinical text is an important task of clinical natural language processing (NLP. Rule-based methods are often used in clinical NLP systems because they are easy to adapt and customize. Recently, supervised machine learning methods have proven to be effective in clinical NLP as well. However, combining different classifiers to further improve the performance of clinical entity recognition systems has not been investigated extensively. Combining classifiers into an ensemble classifier presents both challenges and opportunities to improve performance in such NLP tasks. Methods We investigated ensemble classifiers that used different voting strategies to combine outputs from three individual classifiers: a rule-based system, a support vector machine (SVM based system, and a conditional random field (CRF based system. Three voting methods were proposed and evaluated using the annotated data sets from the 2009 i2b2 NLP challenge: simple majority, local SVM-based voting, and local CRF-based voting. Results Evaluation on 268 manually annotated discharge summaries from the i2b2 challenge showed that the local CRF-based voting method achieved the best F-score of 90.84% (94.11% Precision, 87.81% Recall for 10-fold cross-validation. We then compared our systems with the first-ranked system in the challenge by using the same training and test sets. Our system based on majority voting achieved a better F-score of 89.65% (93.91% Precision, 85.76% Recall than the previously reported F-score of 89.19% (93.78% Precision, 85.03% Recall by the first-ranked system in the challenge. Conclusions Our experimental results using the 2009 i2b2 challenge datasets showed that ensemble classifiers that combine individual classifiers into a voting system could achieve better performance than a single classifier in recognizing medication information from clinical text. It suggests that
Kurian, Allison W; Antoniou, Antonis C; Domchek, Susan M
Recent advances in genomic technology have enabled far more rapid, less expensive sequencing of multiple genes than was possible only a few years ago. Advances in bioinformatics also facilitate the interpretation of large amounts of genomic data. New strategies for cancer genetic risk assessment include multiplex sequencing panels of 5 to more than 100 genes (in which rare mutations are often associated with at least two times the average risk of developing breast cancer) and panels of common single-nucleotide polymorphisms (SNPs), combinations of which are generally associated with more modest cancer risks (more than twofold). Although these new multiple-gene panel tests are used in oncology practice, questions remain about the clinical validity and the clinical utility of their results. To translate this increasingly complex genetic information for clinical use, cancer risk prediction tools are under development that consider the joint effects of all susceptibility genes, together with other established breast cancer risk factors. Risk-adapted screening and prevention protocols are underway, with ongoing refinement as genetic knowledge grows. Priority areas for future research include the clinical validity and clinical utility of emerging genetic tests; the accuracy of developing cancer risk prediction models; and the long-term outcomes of risk-adapted screening and prevention protocols, in terms of patients' experiences and survival. PMID:27249685
Moldovan-Johnson, Mihaela; Tan, Andy SL; Hornik, Robert C
Prior theory has argued and empirical studies have shown that cancer patients rely on information from their health care providers as well as lay sources to understand and make decisions about their disease. However, research on the dynamic and interdependent nature of cancer patients’ engagement with different information sources is lacking. This study tested the hypotheses that patient-clinician information engagement and information seeking from nonmedical sources influence one another longitudinally among a representative cohort of 1,293 cancer survivors in Pennsylvania. The study hypotheses were supported in a series of lagged multiple regression analyses. Baseline seeking information from nonmedical sources positively predicted subsequent patient-clinician information engagement at one-year follow-up. The reverse relationship was also statistically significant; baseline patient-clinician information engagement positively predicted information seeking from nonmedical sources at follow-up. These findings suggest that cancer survivors move between nonmedical to clinician sources in a dynamic way to learn about their disease. PMID:24359259
This report provides summary data for use by the decision board to assess and select the final technology for project W-551, Interim Pretreatment System. This project will provide early pretreated low activity waste feed to the Waste Treatment Plant to allow Waste Treatment Plan Low Activity Waste facility operation prior to construction completion of the Pretreatment and High Level Waste facilities. The candidate solids separations technologies are rotary microfiltration and crossflow filtration, and the candidate cesium separation technologies are fractional crystallization, caustic-side solvent extraction, and ion-exchange using spherical resorcinol-fonnaldebyde resin. This document provides a summary of comparative data against prior weighted criteria to support technology selection. Supporting details and background for this summary are documented in the separate report, RPP-RPT-37741.
Patients increasingly use the Internet for gastric cancer information. However, the quality of the information is questionable. We evaluated the accuracy, completeness, accessibility, reliability, and readability of gastric cancer websites.
Lund, Line; Ross, Lone; Petersen, Morten Aagaard;
PURPOSE: In order to meet the caregiving challenges, informal caregivers often need a substantial level of interaction with health care professionals (HCPs). This study investigated to which extent the cancer caregivers' needs regarding the interaction with HCPs are met and the associations between...... dissatisfaction with the interaction and socio-demographic and disease-related variables. METHODS: In a cross-sectional questionnaire study, cancer patients with various diagnoses and disease stages were invited to pass on the 'cancer caregiving tasks, consequences and needs questionnaire' (CaTCoN) to up to three...... optimal involvement of the caregivers in the patients' disease, treatment and/or care (30 % were dissatisfied), attention to the caregivers' wellbeing (e.g., 51 % of the caregivers reported that HCPs only sometimes or rarely/never had shown interest in how the caregivers had been feeling), and provision...
Befort, Christie A.; Nazir, Niaman; Engelman, Kimberly; Choi, Won
Fatalistic beliefs about cancer prevention can be a significant deterrent to one’s likelihood of engaging in cancer prevention behaviors. Lower education and less access to cancer information among rural residents may influence their level of cancer fatalism. The purpose of this study was to examine rural-urban differences in fatalistic beliefs about cancer prevention and cancer information sources using data from the 2007 Health Information National Trends Survey (n = 1482 rural and 6192 urban residents). Results showed that rural residents were more likely to endorse multiple fatalistic beliefs about cancer prevention than urban residents even after controlling for other significant demographic correlates. Urban residents were more likely to use the internet as their primary cancer information source, whereas rural residents were more likely to rely on print material and healthcare providers. Future educational work to communicate relevant and accurate cancer prevention information to rural residents should consider not only information access but also rural culture and fatalistic perspectives. PMID:23813489
Lipton, Allan; Berenson, James R; Body, Jean-Jacques; Boyce, Brendan F.; Bruland, Oyvind S.; Carducci, Michael A; Cleeland, Charles S.; Clohisy, Denis R.; Coleman, Robert E.; Cook, Richard J.; Guise, Theresa A.; Pearse, Roger N.; Powles, Trevor J; Rogers, Michael J; Roodman, G. David
The First Cambridge Conference on Advances in Treating Metastatic Bone Cancer, a symposium held in Cambridge, Massachusetts, October 28 to 29, 2005, was convened to discuss recent advances and research related to the natural history of bone metastases and skeletal complications, bone cancer biology, treatment of myeloma and other solid tumors, and treatment-induced bone loss. The conference format combined brief presentations with extended periods of discussion. The conclusions reached during...
Expert-reviewed information summary about communicating with the cancer patient and his or her family, including unique aspects of communication with cancer patients, factors affecting communication, and training in communication skills.
Relationship of Internet health information use with patient behavior and self-efficacy: experiences of newly diagnosed cancer patients who contact the National Cancer Institute's Cancer Information Service.
Bass, Sarah Bauerle; Ruzek, Sheryl Burt; Gordon, Thomas F; Fleisher, Linda; McKeown-Conn, Nancy; Moore, Dirk
This study examines the relationship of Internet health information use with patient behavior and self-efficacy among 498 newly diagnosed cancer patients. Subjects were classified by types of Internet use: direct use (used Internet health information themselves), indirect use (used information accessed by friends or family), and non-use (never accessing Internet information). Subjects were recruited from callers of the National Cancer Institute's (NCI's) Cancer Information Service, Atlantic Region. They were classified by type of Internet use at enrollment and interviewed by telephone after 8 weeks. There were significant relationships among Internet use and key study variables: subject characteristics, patient task behavior, and self-efficacy. Subjects' Internet use changed significantly from enrollment to 8 week follow-up; 19% of nonusers and indirect users moved to a higher level of Internet use. Significant relationships also were found among Internet use and perceived patient-provider relationship, question asking, and treatment compliance. Finally, Internet use was also significantly associated with self-efficacy variables (confidence in actively participating in treatment decisions, asking physicians questions, and sharing feelings of concern). The results of this study show that patients who are newly diagnosed with cancer perceive the Internet as a powerful tool, both for acquiring information and for enhancing confidence to make informed decisions. PMID:16537289
Shaw, Bret R.; DuBenske, Lori L.; Han, Jeong Yeob; Cofta-Woerpel, Ludmila; Bush, Nigel; Gustafson, David H.; McTavish, Fiona
Little research has examined the antecedent characteristics of patients most likely to seek online cancer information. This study employs the Cognitive-Social Health Information Processing (C-SHIP) model as a framework to understand what psychosocial characteristics precede online cancer-related information seeking among rural breast cancer patients who often have fewer healthcare providers and limited local support services. Examining 144 patients who were provided free computer hardware, In...
Expert-reviewed information summary about the challenges faced by family caregivers of cancer patients. This summary focuses on typical caregiver roles and concerns, and helpful interventions for caregivers.
Urba Walter J
Full Text Available Abstract The Society for Immunotherapy of Cancer, SITC (formerly the International Society for Biological Therapy of Cancer, iSBTc, aims to improve cancer patient outcomes by advancing the science, development and application of biological therapy and immunotherapy. The society and its educational programs have become premier destinations for interaction and innovation in the cancer biologics community. For over a decade, the society has offered the Primer on Tumor Immunology and Biological Therapy of Cancer™ in conjunction with its Annual Scientific Meeting. This report summarizes the 2010 Primer that took place October 1, 2010 in Washington, D.C. as part of the educational offerings associated with the society's 25th anniversary. The target audience was basic and clinical investigators from academia, industry and regulatory agencies, and included clinicians, post-doctoral fellows, students, and allied health professionals. Attendees were provided a review of basic immunology and educated on the current status and most recent advances in tumor immunology and clinical/translational caner immunology. Ten prominent investigators presented on the following topics: innate immunity and inflammation; an overview of adaptive immunity; dendritic cells; tumor microenvironment; regulatory immune cells; immune monitoring; cytokines in cancer immunotherapy; immune modulating antibodies; cancer vaccines; and adoptive T cell therapy. Presentation slides, a Primer webinar and additional program information are available online on the society's website.
Balogh, Erin P; Ganz, Patricia A; Murphy, Sharon B; Nass, Sharyl J; Ferrell, Betty R; Stovall, Ellen
The Institute of Medicine's National Cancer Policy Forum recently convened a workshop on patient-centered cancer treatment planning, with the aim of raising awareness about this important but often overlooked aspect of cancer treatment. A primary goal of patient-centered treatment planning is to engage patients and their families in meaningful, thorough interactions with their health care providers to develop an accurate, well-conceived treatment plan, using all available medical information appropriately while also considering the medical, social, and cultural needs and desires of the patient and family. A cancer treatment plan can be shared among the patient, family, and care team in order to facilitate care coordination and provide a roadmap to help patients navigate the path of cancer treatment. There are numerous obstacles to achieving patient-centered cancer treatment planning in practice. Some of these challenges stem from the patient and include patients' lack of assertiveness, health literacy, and numeracy, and their emotional state and concurrent illnesses. Others are a result of physician limitations, such as a lack of time to explain complex information and a lack of tools to facilitate treatment planning, as well as insensitivity to patients' informational, cultural, and emotional needs. Potential solutions to address these obstacles include better training of health care providers and patients in optimal communication and shared decision making, and greater use of support services and tools such as patient navigation and electronic health records. Other options include greater use of quality metrics and reimbursement for the time it takes to develop, discuss, and document a treatment plan. PMID:22128118
Hopkins, Valorie; Kinnison, Joyce; Morgenthau, Eleanor; Ollis, Harvey
The National Occupational Information Coordinating Committee/State Occupational Information Coordinating Committees (NOICC/SOICC) Network sponsors numerous occupational information programs and systems, including career information delivery systems (CIDS). CIDS provide useful national, state, and local information for people who are exploring,…
Park, SoHyun; Oh, Heung-Kwon; Park, Gibeom; Suh, Bongwon; Bae, Woo Kyung; Kim, Jin Won; Yoon, Hyuk; Kim, Duck-Woo; Kang, Sung-Bum
Abstract Despite the rapid penetration of social media in modern life, there has been limited research conducted on whether social media serves as a credible source of health information. In this study, we propose to identify colorectal cancer information on Twitter and assess its informational credibility. We collected Twitter messages containing colorectal cancer-related keywords, over a 3-month period. A review of sample tweets yielded content and user categorization schemes. The results of the sample analysis were applied to classify all collected tweets and users, using a machine learning technique. The credibility of the information in the sampled tweets was evaluated. A total of 76,119 tweets were analyzed. Individual users authored the majority of tweets (n = 68,982, 90.6%). They mostly tweeted about news articles/research (n = 16,761, 22.0%) and risk/prevention (n = 14,767, 19.4%). Medical professional users generated only 2.0% of total tweets (n = 1509), and medical institutions rarely tweeted (n = 417, 0.6%). Organizations tended to tweet more about information than did individuals (85.2% vs 63.1%; P public health and empowering users, when used with proper caution. PMID:26886625
Park, SoHyun; Oh, Heung-Kwon; Park, Gibeom; Suh, Bongwon; Bae, Woo Kyung; Kim, Jin Won; Yoon, Hyuk; Kim, Duck-Woo; Kang, Sung-Bum
Despite the rapid penetration of social media in modern life, there has been limited research conducted on whether social media serves as a credible source of health information. In this study, we propose to identify colorectal cancer information on Twitter and assess its informational credibility.We collected Twitter messages containing colorectal cancer-related keywords, over a 3-month period. A review of sample tweets yielded content and user categorization schemes. The results of the sample analysis were applied to classify all collected tweets and users, using a machine learning technique. The credibility of the information in the sampled tweets was evaluated.A total of 76,119 tweets were analyzed. Individual users authored the majority of tweets (n = 68,982, 90.6%). They mostly tweeted about news articles/research (n = 16,761, 22.0%) and risk/prevention (n = 14,767, 19.4%). Medical professional users generated only 2.0% of total tweets (n = 1509), and medical institutions rarely tweeted (n = 417, 0.6%). Organizations tended to tweet more about information than did individuals (85.2% vs 63.1%; P social support, Twitter may contribute to enhancing public health and empowering users, when used with proper caution. PMID:26886625
This paper provides a summary of an OECD workshop on the causes of economic growth, held 6-7 July 2000. The topics covered include the recent growth resurgence in the United States, the potential importance of ICT and the Internet, and the part played by continual reallocation and restructuring. The paper also discusses the growth role of education, institutions, social capital, the financial sector, international trade and foreign direct investment, and indicates how research on these topics...
Objective: One of the basic issues in clinical studies is to receive the informed consent; that is to say, all the activities applied in patient’s involvement in the information, decision-making, ability and volunteering in diagnosis, cure and care. In as much as most cancer patients require information about their individual needs, the present study is conducted to determine the perceived information from the informed consent of clinical studies in cancer patients. Methods: This is a descrip...
Full Text Available India is a high-risk country for cervical cancer which accounts a quarter (126 000 new cases, 71 000 deaths around 2 000 of the world burden. The age-standardized incidence rates range from 16-55 per 100 000 women in different regions with particularly high rates in rural areas. Control of cervical cancer by early detection and treatment is a priority of the National Cancer Control Programme of India. There are no organized cytology screening programmes in the country. The technical and financial constraints to organize cytology screening have encouraged the evaluation of visual inspection approaches as potential alternatives to cervical cytology in India. Four types of visual detection approaches for cervical neoplasia are investigated in India: a naked eye inspection without acetic acid application, widely known as 'downstaging'; b naked eye inspection after application of 3-5% acetic acid (VIA; c VIA using magnification devices (VIAM; d visual inspection after the application of Lugol's iodine (VILI. Downstaging has been shown to be poorly sensitive and specific to detect cervical neoplasia and is no longer considered as a suitable screening test for cervical cancer. VIA, VIAM and VILI are currently being investigated in multicentre cross-sectional studies (without verification bias, in which cytology and HPV testing are also simultaneously evaluated, and the results of these investigations will be available in 2003. These studies will provide valuable information on the average, comparative test performances in detecting high-grade cervical cancer precursors and cancer. Results from pooled analysis of data from two completed studies indicated an approximate sensitivity of 93.4% and specificity of 85.1% for VIA to detect CIN 2 or worse lesions; the corresponding figures for cytology were 72.1% and 91.6%. The efficacy of VIA in reducing incidence of and mortality from cervical cancer and its cost-effectiveness is currently being investigated
Sankaranarayanan, R; Nene, B M; Dinshaw, K; Rajkumar, R; Shastri, S; Wesley, R; Basu, P; Sharma, R; Thara, S; Budukh, A; Parkin, D M
India is a high-risk country for cervical cancer which accounts a quarter (126,000 new cases, 71,000 deaths around 2,000) of the world burden. The age-standardized incidence rates range from 16-55 per 100,000 women in different regions with particularly high rates in rural areas. Control of cervical cancer by early detection and treatment is a priority of the National Cancer Control Programme of India. There are no organized cytology screening programmes in the country. The technical and financial constraints to organize cytology screening have encouraged the evaluation of visual inspection approaches as potential alternatives to cervical cytology in India. Four types of visual detection approaches for cervical neoplasia are investigated in India: a) naked eye inspection without acetic acid application, widely known as 'downstaging'; b) naked eye inspection after application of 3-5% acetic acid (VIA); c) VIA using magnification devices (VIAM); d) visual inspection after the application of Lugol's iodine (VILI). Downstaging has been shown to be poorly sensitive and specific to detect cervical neoplasia and is no longer considered as a suitable screening test for cervical cancer. VIA, VIAM and VILI are currently being investigated in multicentre cross-sectional studies (without verification bias), in which cytology and HPV testing are also simultaneously evaluated, and the results of these investigations will be available in 2003. These studies will provide valuable information on the average, comparative test performances in detecting high-grade cervical cancer precursors and cancer. Results from pooled analysis of data from two completed studies indicated an approximate sensitivity of 93.4% and specificity of 85.1% for VIA to detect CIN 2 or worse lesions; the corresponding figures for cytology were 72.1% and 91.6%. The efficacy of VIA in reducing incidence of an mortality from cervical cancer and its cost-effectiveness is currently being investigated in two
This page lists cancer drugs approved by the Food and Drug Administration (FDA) for cervical cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.
This page lists cancer drugs approved by the Food and Drug Administration (FDA) for testicular cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.
Regan, C.; Lee, S. [Nuclear Regulatory Commission, Washington, DC (United States). Div. of Reactor Program Management; Chopra, O.K.; Ma, D.C.; Shack, W.J. [Argonne National Lab., IL (United States)
In about 1990, the Nuclear Management and Resources Council (NUMARC) submitted for NRC review ten industry reports (IRs) addressing aging issues associated with specific structures and components of nuclear power plants ad one IR addressing the screening methodology for integrated plant assessment. The NRC staff had been reviewing the ten NUMARC IRs; their comments on each IR and NUMARC responses to the comments have been compiled as public documents. This report provides a brief summary of the technical information and NUMARC/NRC agreements from the ten IRs, except for the Cable License Renewal IR. The technical information and agreements documented herein represent the status of the NRC staffs review when the NRC staff and industry resources were redirected to address rule implementation issues. The NRC staff plans to incorporate appropriate technical information and agreements into the draft standard review plan for license renewal.
In about 1990, the Nuclear Management and Resources Council (NUMARC) submitted for NRC review ten industry reports (IRs) addressing aging issues associated with specific structures and components of nuclear power plants ad one IR addressing the screening methodology for integrated plant assessment. The NRC staff had been reviewing the ten NUMARC IRs; their comments on each IR and NUMARC responses to the comments have been compiled as public documents. This report provides a brief summary of the technical information and NUMARC/NRC agreements from the ten IRs, except for the Cable License Renewal IR. The technical information and agreements documented herein represent the status of the NRC staffs review when the NRC staff and industry resources were redirected to address rule implementation issues. The NRC staff plans to incorporate appropriate technical information and agreements into the draft standard review plan for license renewal
Stroncek David F
Full Text Available Abstract A summit on cellular therapy for cancer discussed and presented advances related to the use of adoptive cellular therapy for melanoma and other cancers. The summit revealed that this field is advancing rapidly. Conventional cellular therapies, such as tumor infiltrating lymphocytes (TIL, are becoming more effective and more available. Gene therapy is becoming an important tool in adoptive cell therapy. Lymphocytes are being engineered to express high affinity T cell receptors (TCRs, chimeric antibody-T cell receptors (CARs and cytokines. T cell subsets with more naïve and stem cell-like characteristics have been shown in pre-clinical models to be more effective than unselected populations and it is now possible to reprogram T cells and to produce T cells with stem cell characteristics. In the future, combinations of adoptive transfer of T cells and specific vaccination against the cognate antigen can be envisaged to further enhance the effectiveness of these therapies.
Cancer can be one of the most serious diseases that can result in a costly reduction in the quality of life. Among a number of cancer risk factors, tobacco use has been identified as the leading preventable cause of deaths. Prior research has suggested that cancer information seeking may be a pre-step to adopt health protective behaviors that can…
Full Text Available Breast cancer is the most common malignancy in women worldwide. With the increasing awareness of heterogeneity in breast cancers, better prediction of breast cancer prognosis is much needed for more personalized treatment and disease management. Towards this goal, we have developed a novel computational model for breast cancer prognosis by combining the Pathway Deregulation Score (PDS based pathifier algorithm, Cox regression and L1-LASSO penalization method. We trained the model on a set of 236 patients with gene expression data and clinical information, and validated the performance on three diversified testing data sets of 606 patients. To evaluate the performance of the model, we conducted survival analysis of the dichotomized groups, and compared the areas under the curve based on the binary classification. The resulting prognosis genomic model is composed of fifteen pathways (e.g., P53 pathway that had previously reported cancer relevance, and it successfully differentiated relapse in the training set (log rank p-value = 6.25e-12 and three testing data sets (log rank p-value < 0.0005. Moreover, the pathway-based genomic models consistently performed better than gene-based models on all four data sets. We also find strong evidence that combining genomic information with clinical information improved the p-values of prognosis prediction by at least three orders of magnitude in comparison to using either genomic or clinical information alone. In summary, we propose a novel prognosis model that harnesses the pathway-based dysregulation as well as valuable clinical information. The selected pathways in our prognosis model are promising targets for therapeutic intervention.
Space information countermeasure is a new field of information countermeasure.This paper firstly expatiates the conception of space information countermeasure,then expounds the theory system and technology development of space information counermeasure from three aspects：space information acquirement,space information attack and space information defense,and forecasts the development trend of space information countermeasure,which will be helpful to the development of our military space information countermeasure.%空间信息对抗是信息对抗的一个新的领域。首先阐述了空间信息对抗的概念,然后着重从空间信息获取、空间信息攻击和空间信息防御三个方面对空间信息对抗的理论体系和技术发展进行了综述,并展望了空间信息对抗的发展趋势,以期对我军空间信息对抗的发展有所裨益。
The U.S. Environmental Protection Agency's (EPA) Integrated Risk Information System (IRIS) Program develops assessments of health effects that may result from chronic exposure to chemicals in the environment. The IRIS database contains more than 540 assessments. When supported by available data, IRIS assessments provide quantitative analyses of carcinogenic effects. Since publication of EPA's 2005 Guidelines for Carcinogen Risk Assessment, IRIS cancer assessments have implemented new approaches recommended in these guidelines and expanded the use of complex scientific methods to perform quantitative dose-response assessments. Two case studies of the application of the mode of action framework from the 2005 Cancer Guidelines are presented in this paper. The first is a case study of 1,2,3-trichloropropane, as an example of a chemical with a mutagenic mode of carcinogenic action thus warranting the application of age-dependent adjustment factors for early-life exposure; the second is a case study of ethylene glycol monobutyl ether, as an example of a chemical with a carcinogenic action consistent with a nonlinear extrapolation approach. The use of physiologically based pharmacokinetic (PBPK) modeling to quantify interindividual variability and account for human parameter uncertainty as part of a quantitative cancer assessment is illustrated using a case study involving probabilistic PBPK modeling for dichloromethane. We also discuss statistical issues in assessing trends and model fit for tumor dose-response data, analysis of the combined risk from multiple types of tumors, and application of life-table methods for using human data to derive cancer risk estimates. These issues reflect the complexity and challenges faced in assessing the carcinogenic risks from exposure to environmental chemicals, and provide a view of the current trends in IRIS carcinogenicity risk assessment.
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IRSENDF-6 is a PC code that will process any library in the ENDF-6 format and display information such as: Mat, NE, MT and the corresponding number of records for this information. This library is available on diskette, free of charge, from the IAEA Nuclear Data Section. (author)
Expert-reviewed information summary about post-traumatic stress and related symptoms in cancer patients, cancer survivors, and their family members. Assessment and treatment of these symptoms are discussed.
Expert-reviewed information summary about post-traumatic stress and related symptoms in cancer patients, cancer survivors, and their family members. Assessment and treatment of these symptoms are discussed.
Chris Gunderson is a Research Associate at the Naval Postgraduate School. He is the principal investigator of the Open Enterprise Information System (OEIS) research initiative. This project sponsored by the Undersecretary of Defense for Intelligence and executed in the Northern Virginia. The project objective is to help the government improve its flawed information technology acquisition process through four key activities: Establish a collaborative network of government, industry, and acade...
This document summarizes radioactive waste data records for the Idaho National Engineering Laboratory (INEL) compiled since 1952. Kinds of information include volume, radioactivity, isotopic identity, origin, and decay status. The radioactive waste data presented was obtained from the INEL Radioactive Waste Management Information System (RWMIS). This report is updated annually to incorporate waste management data for the current year and reflects changes in previous annual reports. Changes are made to more accurately reflect the current status of waste operations at the INEL
Vromans, Lisette; Doyle, Gerardine; Petak-Opel, Silvia; Rödiger, Alexander; Röttgermann, Martina; Schlüssel, Elke; Stetter, Eva
Objective To establish, in the context of the revised European Pharmacovigilance Directive and based on physicians’ perspectives, how Summaries of Product Characteristics (SmPCs) could be more user friendly and better support physicians’ interactions with patients, thereby improving patients’ own understanding of their medicines. Design Qualitative focus group discussions (step 1), development of an alternative SmPC (step 2) and an online quantitative survey (step 3) comparing the alternative SmPC to the currently approved version. Setting Office-based physicians (n=218) from all federal states of Germany. Participants 218 German physicians participated, with an equal representation of office-based general practitioners and specialists. For step 1 (n=18), physicians were recruited who frequently consulted SmPCs. Outcome measures Planned and performed: Mayring's qualitative content analysis of focus group discussions (step 1), rating on a five-point Likert scale of preference of current versus alternative SmPCs (step 3). Results Physicians confirmed the importance of SmPCs as a comprehensive source of medicinal product information, but were moderately satisfied with the current SmPCs, utilised it infrequently and were more likely to engage additional sources of information. The alternative SmPC was consistently preferred. It differed in the way information for particular patient groups was presented, included additional sections (synopsis, checklist for patient information) and used a tabular format. Physicians indicated that SmPCs should be available with search and hyperlink functions, as well as be automatically updated and integrated in available practice software or similar solutions. Conclusions This research contributes to the development of an official, reliable medicinal product information system meeting the needs of a modern information society while providing the reliability of an officially authorised source. In the context of health literacy, Sm
The need for a European review of a Risk-Informed Approach for In-Service Inspection of Nuclear Power Plant Components (RIBA) was identified in 1998. This was as a priority item in the programme of activities conducted in the framework of the Council Resolutions of 22 July 1975 and of 18 June 1992 on the Technological Problems of Nuclear Safety. The RIBA Project was established in November 1999 as a 24-month Study Contract funded by the European Commission within the frame of the former DG XI WGCS (Working Group on Codes and Standards). The Study Contract was subsequently managed for the EC by DG TREN. The participants in RIBA were Serco Assurance (project coordinator), Ringhals AB, EDF, Tecnatom SA and Westinghouse Electric Europe. The work is presented in a summary report with the detailed results contained in three companion reports as follows: main conclusions and recommendations, Review of Existing Risk-Informed Methodologies, A Comparative Study of Risk-Informed In-Service Inspection Applications, Conclusions and Recommendations for Risk-Informed in-service inspection methodology applied to Nuclear Power Plants in Europe. (author)
Kent, Erin E; Rowland, Julia H; Northouse, Laurel; Litzelman, Kristin; Chou, Wen-Ying Sylvia; Shelburne, Nonniekaye; Timura, Catherine; O'Mara, Ann; Huss, Karen
Informal/family caregivers are a fundamental source of care for cancer patients in the United States, yet the population of caregivers and their tasks, psychosocial needs, and health outcomes are not well understood. Changes in the nature of cancer care and its delivery, along with the growing population of survivors and their caregivers, warrant increased attention to the roles and demands of caregiving. This article reviews current evidence presented at a 2-day meeting examining the state of the science of informal cancer caregiving that was convened by the National Cancer Institute and the National Institute of Nursing Research. The meeting sought to define who is an informal cancer caregiver, summarize the state of the science in informal cancer caregiving, and describe both the kinds of interventions developed to address caregiving challenges and the various outcomes used to evaluate their impact. This article offers recommendations for moving science forward in 4 areas: 1) improving the estimation of the prevalence and burden of informal cancer caregiving; 2) advancing the development of interventions designed to improve outcomes for cancer patients, caregivers, and patient-caregiver dyads; 3) generating and testing strategies for integrating caregivers into formal health care settings; and 4) promoting the use of technology to support informal cancer caregivers. Cancer 2016;122:1987-95. © 2016 American Cancer Society. PMID:26991807
Pandey, Ambarish; Hasan, Sayeedul; Dubey, Divyanshu; Sarangi, Sasmit
There is an increased interest in smartphone applications as a tool for delivery of health-care information. There have been no studies which evaluated the availability and content of cancer-related smartphone applications. This study aims to identify and analyze cancer-related applications available on the Apple iTunes platform. The Apple iTunes store was searched for cancer-related smartphone applications on July 29, 2011. The content of the applications was analyzed for cost, type of information, validity, and involvement of health-care agencies. A total of 77 relevant applications were identified. There were 24.6 % apps uploaded by health-care agencies, and 36 % of the apps were aimed at health-care workers. Among the apps, 55.8 % provided scientifically validated data. The difference in scientific validity between the apps aimed at general population versus health-care professionals was statistically significant (P smartphone applications and encourage participation by health-care agencies to ensure patient safety. PMID:23275239
Singer, Brett C.; Coughlin, Jennifer L.; Mathew, Paul A.
This document presents the results of a review of publicly available information on energy use in health care facilities. The information contained in this document and in the sources cited herein provides the background and context for efforts to reduce energy use and costs in health care. Recognizing the breadth and diversity of relevant information, the author acknowledges that the report is likely not comprehensive. It is intended only to present a broad picture of what is currently known about health care energy use. This review was conducted as part of a 'High Performance Health Care Buildings' research study funded by the California Energy Commission. The study was motivated by the recognition that health care facilities collectively account for a substantial fraction of total commercial building energy use, due in large part to the very high energy intensity of hospitals and other inpatient care facilities. The goal of the study was to develop a roadmap of research, development and deployment (RD&D) needs for the health care industry. In addition to this information review, the road map development process included interviews with industry experts and a full-day workshop at LBNL in March 2009. This report is described as 'Version 1' with the intent that it will be expanded and updated as part of an ongoing LBNL program in healthcare energy efficiency. The document is being released in this form with the hope that it can assist others in finding and accessing the resources described within.
Lee, C.R.; Brandon, D.L.; Simmers, J.W.; Tatem, H.E.; Skogerbee, J.G.
The Great Lakes National Program Office (GLNPO) is carrying out a 5-year study and demonstration project, Assessment and Remediation of Contaminated Sediments (ARCS), with emphasis on removal of toxic pollutants from bottom sediments. Information from the ARCS program is to be used to guide development of Remedial Action Plans for 42 identified Great Lakes Areas of Concern (AOCs). The AOCs are areas where serious impairment of beneficial uses of water or biota (drinking, swimming, fishing, navigation, etc.) is known to exist, or where environmental quality criteria are exceeded to the point that such impairment is likely. Priority consideration was given to five AOCs, including Buffalo River, N.Y. The WES Environmental Lab. reviewed existing data and information for each of these five AOCs. The approach used was to bring together WES scientists who have been conducting research on aspects of contaminant mobility in the aquatic environment to develop a list of information required to evaluate the potential for contaminant mobility. This report summarizes the information obtained for the Buffalo River. Topics include: Fish tissue concentrations, Groundwater, Land use, Metal contamination, Pesticides, Point and nonpoint source discharges, Risk assessment, Spills, Toxicity bioassay, and Water quality.
Brandon, D.L.; Lee, C.R.; Simmers, J.W.; Tatem, H.E.; Skogerboe, J.G.
A 5-year study and demonstration project, Assessment and Remediation of Contaminated Sediments (ARCS) was authorized, with emphasis on the removal of toxic pollutants from bottom sediments. Information from the ARCS program is to be used to guide the development of Remedial Action Plans (RAPs) for 42 identified great Lakes Areas of Concern (AOC) as well as Lake-wide Management Plans. The AOCs are areas where serious impairment of beneficial uses of water or biota (drinking, swimming, fishing, navigation, etc.) is known to exist, or where environmental quality criteria are exceeded to the point that such impairment is likely. Research was conducted on the various aspects of contaminant mobility in the aquatic environment. A list of information was developed to evaluate the potential for contaminant mobility. This report summarizes the information obtained for the Saginaw River and Saginaw Bay AOC in Michigan. Data tables include information on discharge, volume and migration of contaminants, sediment transport, oil spills, hazardous materials, superfund sites, bioassay data and biological data (i.e. fish, wildlife habitats, plankton, fish and endangered species).
Kloda, Lorie A.; Koufogiannakis, Denise; Mallan, Katrine
Introduction: Critical appraisal is a crucial aspect of evidence-based practice. In order to determine whether research is valid, reliable and applicable, the evidence-based practice process advocates that published research be critically appraised. Between 2006 and 2008, the journal Evidence Based Library and Information Practice published 101…
The solid radioactive waste (generated, buried, and stored) information throughout the Department of Energy (DOE) are maintained on the Solid Waste Information Management System (SWIMS) data base. DOE Order 5820, ''Radioactive Waste Management,'' requires that DOE maintain information on radioactive solid waste. The SWIMS data base contains data on the solid transuranic (TRU) and solid low-level waste (LLW) generated, buried, or stored at DOE sites. The generation data covers the period from the FY 1976 transition quarter through CY 1985. The burial and storage data include the period from site initiation through CY 1985. This document contains reports based on CY 1985 data and CY 1986 forecasts from SWIMS and summarized at the DOE level. Detailed reports of the data summarized at DOE operations office level are also included in the appendices. To aid in separating TRU data from LLW data, information in each report is detailed by nuclide category. The eight nuclide categories are contact handled (TRU), uranium/thorium (LLW, fission product (LLW, induced activity (LLW), tritium (LLW), remote handled (TRU), alpha (LLW), and other
Smith, S. G.; Vart, G.; Wolf, M. S.; Obichere, A; Baker, H. J.; Raine, R; Wardle, J.; Von Wagner, C.
The English NHS Bowel Cancer Screening Programme biennially invites individuals aged 60-74 to participate in screening. The booklet, 'Bowel Cancer Screening: The Facts' accompanies this invitation. Its primary aim is to inform potential participants about the aims, advantages and disadvantages of colorectal cancer screening.
Bonanno, Giacomo; Delgrande, James; Rott, Hans
From August 23, 2009 to August 27, 2009, the Dagstuhl Seminar 09351 "Information processing, rational belief change and social interaction" was held at the International Conference and Research Center (IBFI), Schloss Dagstuhl. During the seminar, several participants presented their current research, and ongoing work and open problems were discussed. Abstracts of the presentations given during the seminar as well as abstracts of seminar results and ideas are put togethe...
Doan Son; Collier Nigel; Xu Hua; Duy Pham; Phuong Tu
Abstract Background Extraction of clinical information such as medications or problems from clinical text is an important task of clinical natural language processing (NLP). Rule-based methods are often used in clinical NLP systems because they are easy to adapt and customize. Recently, supervised machine learning methods have proven to be effective in clinical NLP as well. However, combining different classifiers to further improve the performance of clinical entity recognition systems has n...
Halgrim Scott; Xia Fei; Solti Imre; Cadag Eithon; Uzuner Özlem
Abstract Background Extracting medication information from clinical records has many potential applications, and recently published research, systems, and competitions reflect an interest therein. Much of the early extraction work involved rules and lexicons, but more recently machine learning has been applied to the task. Methods We present a hybrid system consisting of two parts. The first part, field detection, uses a cascade of statistical classifiers to identify medication-related named ...
Fenner-Crisp, P. [Environmental Protection Agency, Washington, DC (United States)
The application of information available for risk assessment from the federal perspective is described. Different federal agencies conduct varying degrees of hazard evaluation, and some also generate empirical data. The role of the Agency for Toxic Substances and Disease Registry in hazard assessments of potential public health impacts of Superfund sites includes identification of the 275 most significant substances. ATSDR is responsible for preparing toxicological profiles. ATSDR also identifies data gaps and needs critical to adequately assessing human health impacts.
Schönfeld, I; Kraywinkel, K
Finding reliable data about cancer epidemiology on the World Wide Web is not an easy task. Information is often scattered, and sources are not always clear. This article gives a short overview of the most important websites that provide reliable data for Germany and Europe. Four internet sites are presented: The German Centre for Cancer Registry Data (ZfKD), the Association of Population-Based Cancer Registries in Germany (GEKID), and two different websites created by the International Agency for Research on Cancer (IARC). In combination, they provide comprehensive information about the distribution of cancer in Germany and Europe. PMID:24357168
Ltd, Compass Informatics; Ireland, Inland Fisheries; National University of Ireland, Galway
The overall aim of the project was to establish an information management framework for the development of River Basin Eel Management Plans (EMP). This involved the collation of base information to assist the publication of the initial National Plan (DCENR 2008) and, importantly, the establishment of a GIS and database system for continued information collation, analysis, management and planning. This report is the summary report of this project.
Full text: The large transboundary effects of the radioactive release during the Chernobyl accident evidenced the need for international provisions for data and Information exchange. The JRC, in its EC support activity to DG TREN H.4, called REM (Radioactivity Environmental Monitoring), has more than 10 years experience in developing systems to make early notification and reliable radiological information exchange available to the EU member states in case of nuclear accidents. The aim and status of these systems are described: 1.)ECURIE: The legal basis for the EC systems is the Council Decision 87/600 of 14 December 1987. It resulted in the ECURIE network which allows the EU Member States and Switzerland to notify an accident and to subsequently exchange the radiological information as required by this Council decision. The underlying information exchange code (C.1. structure) does not only provide radiological measurements, but also predicted values, site meteorological data and decisions taken. Software was developed to facilitate coding and decoding of the messages. Initially the messages were transmitted by telex. The latest software (CoDecS, in use since the beginning of 2001) uses ISDN and Internet for the Information exchange. lt runs an the Windows NT and 2000 platforms. Regular exercises test the communication system and the software. In view of improving the efficiency of data and Information transfer for their common Member States, the IAEA and the EC are harmonizing ECURIE and the ENATOM early notification system. A first result has been the definition of an enhanced CIS format. Modifications will be made to the CoDecs software and to the IAEA - ENAC website so that information can be exchanged between the two systems in an automated manner. The EC wishes to extend the ECURIE network to the EU candidate countries. The official agreements are in an advanced state and participation of many candidate countries is foreseen by the end of 2003. It is
The environmental measurements and geographic data bases of the Oak Ridge Environmental Information System (OREIS) contain data of known quality that can be accessed by OREIS users. The data within OREIS include environmental measurements data from the following environmental media: groundwater, surface water, sediment, soils, air, and biota. The types of environmental data within OREIS include but are not limited to chemical, biological, ecological, radiological, geophysical, and lithological data. Coordinate data within the environmental measurements data base provide the spatial context of the measurements data and are used to link the measurements data to the geographic data base. Descriptive and qualifier metadata are also part of the data bases. As of 30 September 1994, the OREIS environmental measurements data base consisted of approximately 380,000 rows associated with data generated by environmental restoration projects. The data base also contained 3,400 supporting codes and other reference data rows. Geographic data included the S-16A base map for the Oak Ridge Reservation, boundaries for operable units and ORNL waste area groupings, boundaries of groundwater coordination areas, contours generated as a result of the gamma radiation survey, representations of the environmentally sensitive areas, information received as part of the remedial investigation of East Fork Poplar Creek, high resolution background raster images for the three ORR installations, and locations of wells and other point features generated from ORACLE tables
... common treatment for all stages of lip and oral cavity cancer. Surgery may include the following: Wide local excision : Removal ... cancer may have spread from the lip and oral cavity. Plastic surgery : An operation that restores or improves the appearance ...
Beeken, R J; Williams, K; Wardle, J; Croker, H
Given the abundance of misreporting about diet and cancer in the media and online, cancer survivors are at risk of misinformation. The aim of this study was to explore cancer survivors' beliefs about diet quality and cancer, the impact on their behaviour and sources of information. Semi-structured interviews were conducted with adult cancer survivors in the United Kingdom who had been diagnosed with any cancer in adulthood and were not currently receiving treatment (n = 19). Interviews were analysed using Thematic Analysis. Emergent themes highlighted that participants were aware of diet affecting risk for the development of cancer, but were less clear about its role in recurrence. Nonetheless, their cancer diagnosis appeared to be a prompt for dietary change; predominantly to promote general health. Changes were generally consistent with healthy eating recommendations, although dietary supplements and other non-evidence-based actions were mentioned. Participants reported that they had not generally received professional advice about diet and were keen to know more, but were often unsure about information from other sources. The views of our participants suggest cancer survivors would welcome guidance from health professionals. Advice that provides clear recommendations, and which emphasises the benefits of healthy eating for overall well-being, may be particularly well-received. PMID:27349812
Simmers, J.W.; Lee, C.R.; Brandon, D.L.; Tatem, H.E.; Skogerboe, J.G.
A 5-year study and demonstration project, Assessment and Remediation of Contaminated Sediment (ARCS), emphasizes the removal of toxic pollutants from bottom sediments. Information from the ARCS program is to be used to guide the development of Remedial Action Plans (RAPs) for 42 identified Great Lakes Areas of Concern (AOCs) as well as resource management plans. The AOCs are areas where serious impairment of beneficial uses of water or biota (drinking, swimming, fishing, navigation, etc) is known to exist, or where environmental quality criteria are exceeded to the point that such impairment is likely. Among the hazardous materials detected from sampling of sediments are heavy metals, pesticides, various chemicals and industrial wastes. Industrial land use, runoff from watersheds, landfills, waste disposal practices and ground water flow contributed to pollutants found in bottom sediments of rivers and waterways channels.
Due to situations beyond our control, and a need to re-direct our budget resources, this will be the last issue of The Information Report on State Legislation, NUREG/BR-0025. There have been several noteworthy events which have occurred since our last issue in July 1984. In the low-level waste area, the Midwest Compact was introduced in both Houses of Congress (S. 3091, H.R. 6937), for a total of five compacts to be considered for consent in the next congressional session (Northwest, Central, Rocky Mountain, Midwest and Southeast). All five must be re-introduced in the 99th Congress. Representative Morris Udall (D-AZ) has proposed a series of amendments to the compact bills and to the Low-Level Radioactive Waste Policy Act which address the problems of states without sites after the 1986 deadline. The amendments also concern issues such as volume reduction, the definition of low-level waste, and import/export of waste outside regional boundaries. The staff of the Senate Judiciary Committee also proposed certain conditions to Congressional consent for the compacts. The conditions included use of NRC-proposed consent language, the low-level waste definition and NRC report requirements. The Office of State Programs (OSP) held a workshop in May 1984 on shallow land burial and alternative low-level waste technologies. The Western Low-Level Radioactive Waste Compact failed in the closing two days of the California Legislature, although it was enacted by Arizona, the only other eligible state. A working group on HLW siting, sponsored by the National Conference of State Legislatures (NCSL), convened December 4-6, 1984, in Las Vegas, Nevada, to inform key legislators and their staffs from the 23 states where DOE is conducting geologic studies for siting two HLW repositories about DOE's progress in implementing the Nuclear Waste Policy Act
... document due to errors found on our first publication of June 27, 2013 ( http://www.gpo.gov/fdsys/pkg/FR... HUMAN SERVICES Agency for Healthcare Research and Quality Scientific Information Request on Imaging...), HHS. ACTION: Request for scientific information submissions. SUMMARY: The Agency for...
Bausewein, Claudia; Booth, Sara; Gysels, Marjolein; Kühnbach, Robert; Haberland, Birgit; Higginson, Irene J
Breathlessness is a distressing symptom in advanced disease. Little is known about the trajectories of this symptom over time and towards death. This study aimed to describe and compare the summary and individual trajectories of breathlessness and overall symptom burden over time and towards the end of life following patients with advanced cancer or severe chronic obstructive pulmonary disease (COPD) in inpatient and outpatient health care settings in Germany. The modified Borg Scale, Memorial Symptom Assessment Scale Short Form and Palliative Outcome Scale were used as outcome measures. Data were collected at baseline and then monthly over six months or until death. Forty-nine cancer and 60 COPD patients were included. Both groups had similar demographics. Thirty out of the 49 cancer and 6/60 COPD patients died, 7/49 cancer and 20/60 COPD patients dropped out due to physical deterioration or questionnaire fatigue. In cancer patients, breathlessness increased towards death. In COPD patients, breathlessness increased over time. Twenty-one cancer and 43 COPD patients provided data for individual breathlessness trajectories. These revealed wide individual variations with four different patterns: fluctuation, increasing, stable and decreasing breathlessness. Symptom trajectories on the population level reflecting the whole group mask individual variation, which is reflected in distinct symptom trajectories with different patterns. PMID:20847087
Oh, KM; Jun, J; Zhao, X.; Kreps, GL; Lee, EE
Copyright © Taylor & Francis Group, LLC 2015. Despite the high risk of cancer to the population, Korean Americans are known to have lower knowledge about cancer related information and a lower level of adherence to cancer prevention guidelines. This indicates the necessity of cancer interventions targeting the Korean American population. To reach this population effectively, it is imperative to understand Korean Americans cancer information seeking behaviors. This study (a) identified cancer ...
Armstrong, Katrina; Kim, Jane J; Halm, Ethan A; Ballard, Rachel M; Schnall, Mitchell D
Multiple advisory groups now recommend that high-risk smokers be screened for lung cancer by low-dose computed tomography. Given that the development of lung cancer screening programs will face many of the same issues that have challenged other cancer screening programs, the National Cancer Institute-funded Population-based Research Optimizing Screening through Personalized Regimens (PROSPR) consortium was used to identify lessons learned from the implementation of breast, cervical, and colorectal cancer screening that should inform the introduction of lung cancer screening. These lessons include the importance of developing systems for identifying and recruiting eligible individuals in primary care, ensuring that screening centers are qualified and performance is monitored, creating clear communication standards for reporting screening results to referring physicians and patients, ensuring follow-up is available for individuals with abnormal test results, avoiding overscreening, remembering primary prevention, and leveraging advances in cancer genetics and immunology. Overall, this experience emphasizes that effective cancer screening is a multistep activity that requires robust strategies to initiate, report, follow up, and track each step as well as a dynamic and ongoing oversight process to revise current screening practices as new evidence regarding screening is created, new screening technologies are developed, new biological markers are identified, and new approaches to health care delivery are disseminated. Cancer 2016;122:1338-1342. © 2016 American Cancer Society. PMID:26929386
The authors investigate the sensitivity of optimal carbon control strategies to parameters of the Carbon Emissions Trajectory Assessment (CETA) Model, and they use CETA in a simple decision tree framework to estimate the value of information about global warming uncertainties. They find that if an optimal control policy is used under uncertainty, the eventual resolution of uncertainty has high value relative to current research budgets, and resolving uncertainty about the costs of warming is nearly as important as resolving uncertainty about the extent of warming. In addition, the authors find that there is not a high premium on immediate resolution of uncertainty, if resolution would otherwise occur within, say, twenty years; this implies that time is available to plan and execute a carefully designed research program. On the other hand, they find that if the real-world political process would result in a suboptimal control policy being chosen under uncertainty, and this choice could be prevented by early resolution of uncertainty, the benefit of early resolution may be as much as three orders of magnitude greater
The data base of the Oak Ridge Environmental Information System (OREIS) contains data of known quality that can be accessed by OREIS users. OREIS meets data management/access requirements for environmental data as specified in the Federal Facility Agreement for the Oak Ridge Reservation and the State Oversight Agreement between the State of Tennessee and the Department of Energy. The types of environmental data within OREIS include measurement data from the following environmental disciplines: groundwater, surface water, sediment, soils, air, and biota. In addition to measurement data, the OREIS data base contains extensive descriptive and qualifier metadata to help define data quality and to enable end users to analyze the appropriateness of data for their purposes. Another important aspect of measurement data is their spatial context; OREIS maintains a comprehensive library of geographic data and tools to analyze and display spatial relationships of the data. As of November 1993, the OREIS data base consists of approximately 100,000 records associated with three environmental restoration projects along with coordinate data and background map data. The data base also contains 2,700 supporting codes and other reference data records. Geographic data include the S-16A base map for the Oak Ridge Reservation, boundaries for operable units, and high-resolution raster images for each of the sites
McCord, R.A.; Herr, D.D.; Durfee, R.C.; Land, M.L.; Monroe, F.E.; Olson, R.J.; Thomas, J.K.; Tinnel, E.P.
The data base of the Oak Ridge Environmental Information System (OREIS) contains data of known quality that can be accessed by OREIS users. OREIS meets data management/access requirements for environmental data as specified in the Federal Facility Agreement for the Oak Ridge Reservation and the State Oversight Agreement between the State of Tennessee and the Department of Energy. The types of environmental data within OREIS include measurement data from the following environmental disciplines: groundwater, surface water, sediment, soils, air, and biota. In addition to measurement data, the OREIS data base contains extensive descriptive and qualifier metadata to help define data quality and to enable end users to analyze the appropriateness of data for their purposes. Another important aspect of measurement data is their spatial context; OREIS maintains a comprehensive library of geographic data and tools to analyze and display spatial relationships of the data. As of November 1993, the OREIS data base consists of approximately 100,000 records associated with three environmental restoration projects along with coordinate data and background map data. The data base also contains 2,700 supporting codes and other reference data records. Geographic data include the S-16A base map for the Oak Ridge Reservation, boundaries for operable units, and high-resolution raster images for each of the sites.
Caley, S.M.; Mahoney, L.A.; Gauglitz, P.A.
The Hanford Site has 149 single-shell tanks (SSTs) containing radioactive wastes that are complex mixes of radioactive and chemical products. Active use of these SSTs was phased out completely by November 1980, and the first step toward final disposal of the waste in the SSTs is interim stabilization, which involves removing essentially all of the drainable liquid from the tank. Stabilization can be achieved administratively, by jet pumping to remove drainable interstitial liquid, or by supernatant pumping. To date, 116 tanks have been declared interim stabilized; 44 SSTs have had drainable liquid removed by salt well jet pumping. Of the 149 SSTs, 19 are on the Flammable Gas Watch List (FGWL) because the waste in these tanks is known or suspected, in all but one case, to generate and retain mixtures of flammable gases, including; hydrogen, nitrous oxide, and ammonia. Salt well pumping to remove the drainable interstitial liquid from these SSTs is expected to cause the release of much of the retained gas, posing a number of safety concerns. The scope of this work is to collect and summarize information, primarily tank data and observations, that relate salt well pumping to flammable gas safety issues. While the waste within FGWL SSTs is suspected offering flammable gases, the effect of salt well pumping on the waste behavior is not well understood. This study is being conducted for the Westinghouse Hanford Company as part of the Flammable Gas Project at the Pacific Northwest National Laboratory (PNNL). Understanding the historical tank behavior during and following salt well pumping will help to resolve the associated safety issues.
The Hanford Site has 149 single-shell tanks (SSTs) containing radioactive wastes that are complex mixes of radioactive and chemical products. Active use of these SSTs was phased out completely by November 1980, and the first step toward final disposal of the waste in the SSTs is interim stabilization, which involves removing essentially all of the drainable liquid from the tank. Stabilization can be achieved administratively, by jet pumping to remove drainable interstitial liquid, or by supernatant pumping. To date, 116 tanks have been declared interim stabilized; 44 SSTs have had drainable liquid removed by salt well jet pumping. Of the 149 SSTs, 19 are on the Flammable Gas Watch List (FGWL) because the waste in these tanks is known or suspected, in all but one case, to generate and retain mixtures of flammable gases, including; hydrogen, nitrous oxide, and ammonia. Salt well pumping to remove the drainable interstitial liquid from these SSTs is expected to cause the release of much of the retained gas, posing a number of safety concerns. The scope of this work is to collect and summarize information, primarily tank data and observations, that relate salt well pumping to flammable gas safety issues. While the waste within FGWL SSTs is suspected offering flammable gases, the effect of salt well pumping on the waste behavior is not well understood. This study is being conducted for the Westinghouse Hanford Company as part of the Flammable Gas Project at the Pacific Northwest National Laboratory (PNNL). Understanding the historical tank behavior during and following salt well pumping will help to resolve the associated safety issues
Kelly, Kimberly M; Shedlosky-Shoemaker, Randi; Porter, Kyle; Desimone, Philip; Andrykowski, Michael
Despite a growing literature on the psychosocial impact of the threat of cancer recurrence, underserved populations, such as those from the Appalachian region, have been understudied. To examine worry and perceived risk in cancer survivors, Appalachian and non-Appalachian cancer patients at an ambulatory oncology clinic in a university hospital were surveyed. Appalachians had significantly higher worry than non-Appalachians. Cancer type and lower need for cognition were associated with greater worry. Those with missing perceived risk data were generally older, less educated, and lower in monitoring, blunting, and health literacy. Additional resources are needed to assist Appalachians and those with cancers with poor prognoses (e.g., liver cancer, pancreatic cancer) to cope with worry associated with developing cancer again. More attention for cancer prevention is critical to improve quality of life in underserved populations where risk of cancer is greater. PMID:21240722
Angelos P. Kassianos
Full Text Available The aim of this study is to explore the information needs of men with prostate cancer and their partners retrospectively at various points in the treatment process. An online questionnaire was used to collect information from men with prostate cancer and their partners about information needs, and when these developed. Readers of a Prostate Care Cookbook and members of a Prostate Cancer Charity were invited to participate: 73 men with prostate cancer and 25 partners completed the questionnaire. Responses showed that participants develop their information needs close to diagnosis. Less educated men with prostate cancer and partners developed their needs closer to the time after diagnosis than those with higher education. Partners develop an interest on information related to treatment and interaction earlier than patients. Patients prioritised treatment and disease-specific information. Patients and partners differ in how their information needs develop. Medical information is prioritized by patients as opposed to practical information by partners. Health care provision can be tailored to meet the different needs of prostate cancer patients and their partners at different times in the treatment process
Kassianos, Angelos P; Raats, Monique M; Gage, Heather
The aim of this study is to explore the information needs of men with prostate cancer and their partners retrospectively at various points in the treatment process. An online questionnaire was used to collect information from men with prostate cancer and their partners about information needs, and when these developed. Readers of a Prostate Care Cookbook and members of a Prostate Cancer Charity were invited to participate: 73 men with prostate cancer and 25 partners completed the questionnaire. Responses showed that participants develop their information needs close to diagnosis. Less educated men with prostate cancer and partners developed their needs closer to the time after diagnosis than those with higher education. Partners develop an interest on information related to treatment and interaction earlier than patients. Patients prioritised treatment and disease-specific information. Patients and partners differ in how their information needs develop. Medical information is prioritized by patients as opposed to practical information by partners. Health care provision can be tailored to meet the different needs of prostate cancer patients and their partners at different times in the treatment process. PMID:27403460
Friedman, Daniela B; Hoffman-Goetz, Laurie
Ethnic minority populations prefer cancer information that is respectful of their customs and beliefs about health and illness. Community newspapers are an important source of cancer information for ethnic groups. Our purpose is to evaluate the cultural sensitivity of cancer information in mass print media targeting ethnic minority readership. We assessed for cultural sensitivity 27 cancer articles published in English-language ethnic newspapers (Jewish, First Nations, Black/Caribbean, East Indian) in 2000 using the Cultural Sensitivity Assessment Tool (CSAT). We found that the overall average CSAT score of 27 cancer articles was 2.71. (Scorespapers. Cancer articles from East Indian newspapers had a mean CSAT score of 2.30 and were classified as culturally insensitive. Four articles were considered culturally sensitive but did not mention ethnic populations as intended readers or as high-risk groups for cancer. We found that, using the CSAT measure, overall, cancer articles in ethnic newspapers included in this study were culturally sensitive. Given limitations of this instrument, we recommend an additional checklist for evaluating the cultural sensitivity of printed cancer information. PMID:16720539
SELSKY, CLAIRE; LUTA, GEORGE; NOONE, ANNE-MICHELLE; HUERTA, ELMER E.; MANDELBLATT, JEANNE S.
Internet use is widespread, but little is known about Internet use for cancer information among Latinos, especially those who rely on safety net clinics. The authors investigated access to and intended use of the Internet for cancer information among low income, immigrant Latinos predominately from Central and South America. A cross-sectional study of 1,273 Latinos 21 years and older attending safety net clinics or health fairs was conducted from June 2007 to November 2008. The authors used logistic regression models to evaluate associations of age, acculturation, psychosocial factors and other covariates with Internet access and intended use of the Internet for cancer information among those with access. Of the sample, 44% reported Internet access. Higher information self-efficacy and greater trust in the Internet were independently associated with Internet access (p= .05 and p < .001, respectively). Among those with access, 53.8% reported they intended to seek cancer help online if they needed information. Those with younger age and higher acculturation, education and self-efficacy had higher odds of intended Internet use for cancer information, considering covariates. In addition, those with high (vs. low) perceived risk of cancer (OR = 1.76; 95% CI [1.14, 2.73]; p = .01) and higher levels of trust in online health information (OR = 1.47 per one-point increase; 95% [CI 1.19, 1.82]; p = .0004) were more likely to intend to seek cancer information online. These findings that Internet access is fairly high in the immigrant Latino population and that the Internet is a trusted source of cancer information suggest that the Internet may be a channel for cancer control interventions. PMID:23066874
Quinn, E M
Studies show internet sourced information often has poor accuracy. However, it is rapidly becoming a major source of patient information. Our aim was to assess accuracy of breast cancer-related information on the internet. The top five breast cancer-related search terms were identified using the commercial program "Wordtracker". These terms were searched using the search-engine "Google" and the top 100 webpages per topic analysed for applicability and accuracy of information. Overall 500 webpages were analysed. 42% were inapplicable to the question asked. Applicable accuracy rates were variable amongst the five terms: "breast cancer symptoms" 84%, "breast cancer care" 87%, "breast cancer stage" 88%, "breast cancer survival" 91% and "breast cancer signs" 78%. Educational websites were more likely to be accurate(p < 0.001) and interest group administered websites less likely to be accurate(p = 0.018) than other websites. Finding accurate breast cancer information on the internet is difficult due to large numbers of inapplicable unregulated websites preferentially returned via search engines.
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Full Text Available Cancer pain is multifactorial and complex. The impact of cancer pain is devastating, with increased morbidity and poor quality of life, if not treated adequately. Cancer pain management is a challenging task both due to disease process as well as a consequence of treatment-related side-effects. Optimization of analgesia with oral opioids, adjuvant analgesics, and advanced pain management techniques is the key to success for cancer pain. Early access of oral opioid and interventional pain management techniques can overcome the barriers of cancer pain, with improved quality of life. With timely and proper anticancer therapy, opioids, nerve blocks, and other non-invasive techniques like psychosocial care, satisfactory pain relief can be achieved in most of the patients. Although the WHO Analgesic Ladder is effective for more than 80% cancer pain, addition of appropriate adjuvant drugs along with early intervention is needed for improved Quality of Life. Effective cancer pain treatment requires a holistic approach with timely assessment, measurement of pain, pathophysiology involved in causing particular type of pain, and understanding of drugs to relieve pain with timely inclusion of intervention. Careful evaluation of psychosocial and mental components with good communication is necessary. Barriers to cancer pain management should be overcome with an interdisciplinary approach aiming to provide adequate analgesia with minimal side-effects. Management of cancer pain should comprise not only a physical component but also psychosocial and mental components and social need of the patient. With risk-benefit analysis, interventional techniques should be included in an early stage of pain treatment. This article summarizes the need for early and effective pain management strategies, awareness regarding pain control, and barriers of cancer pain.
Cull, A; Miller, H.; Porterfield, T.; Mackay, J.; Anderson, E D; Steel, C. M.; Elton, R. A.
A video of introductory information about inherited susceptibility to breast cancer was made in consultation with clinicians in four Scottish cancer family clinics. One hundred and twenty-eight women, newly referred for breast cancer risk counselling were randomized to receive the video before (n = 66) or after (n = 62) counselling. Data were collected before randomization at clinic and by postal follow-up at 1 month. The Video Before group had shorter consultations with the breast surgeon (m...
Squiers, Linda; Bush, Nigel; Vanderpool, Robin; Cofta-Woerpel, Ludmila; Fabrizio, Cecilia
As a collaboratory for cancer communication and education research, the National Cancer Institute’s (NCIs) Cancer Information Service (CIS) is in an ideal position to bridge the critical chasm that exists between service and research. This article describes the CIS’ current research program as well as the CIS Research Agenda launched in 2005. The CIS’ progress in developing and supporting recently funded studies that address this agenda is detailed. The unique resources and opportunities avai...
Peters, Ellen; Diefenbach, Michael A.; Hess, Thomas M.; Västfjäll, Daniel
Age differences in affective/experiential and deliberative processes have important theoretical implications for cancer decision making as cancer is often a disease of older adulthood. We examine evidence for adult age differences in affective and deliberative information processes, review the sparse evidence about age differences in decision making and introduce how dual process theories and their findings might be applied to cancer decision making. Age-related declines in the efficiency of ...
Silveira Maria J
Full Text Available Abstract Background Previous studies have found that cancer patients undergoing chemotherapy can effectively manage their own symptoms when given tailored advice. This approach, however, may challenge patients with poor performance status and/or emotional distress. Our goal is to test an automated intervention that engages a friend or family member to support a patient through chemotherapy. Methods/Design We describe the design and rationale of a randomized, controlled trial to assess the efficacy of 10 weeks of web-based caregiver alerts and tailored advice for helping a patient manage symptoms related to chemotherapy. The study aims to test the primary hypothesis that patients whose caregivers receive alerts and tailored advice will report less frequent and less severe symptoms at 10 and 14 weeks when compared to patients in the control arm; similarly, they will report better physical function, fewer outpatient visits and hospitalizations related to symptoms, and greater adherence to chemotherapy. 300 patients with solid tumors undergoing chemotherapy at two Veteran Administration oncology clinics reporting any symptom at a severity of ≥4 and a willing informal caregiver will be assigned to either 10 weeks of automated telephonic symptom assessment (ATSA alone, or 10 weeks of ATSA plus web-based notification of symptom severity and problem solving advice to their chosen caregiver. Patients and caregivers will be surveyed at intake, 10 weeks and 14 weeks. Both groups will receive standard oncology, hospice, and palliative care. Discussion Patients undergoing chemotherapy experience many symptoms that they may be able to manage with the support of an activated caregiver. This intervention uses readily available technology to improve patient caregiver communication about symptoms and caregiver knowledge of symptom management. If successful, it could substantially improve the quality of life of veterans and their families during the stresses of
Expert-reviewed information summary about the genomics of childhood cancer. The summary describes the molecular subtypes for specific pediatric cancers and their associated clinical characteristics, the recurring genomic alterations that characterize each subtype at diagnosis or relapse, and the therapeutic and prognostic significance of the genomic alterations. The genomic alterations associated with brain tumors, kidney tumors, leukemias, lymphomas, sarcomas, and other cancers are discussed.
Kelly, Kimberly M.; Shedlosky-Shoemaker, Randi; Porter, Kyle; DeSimone, Philip; Andrykowski, Michael
Despite a growing literature on the psychosocial impact of the threat of cancer recurrence, underserved populations, such as those from the Appalachian region, have been understudied. To examine worry and perceived risk in cancer survivors, cancer patients at an ambulatory oncology clinic in a university hospital were surveyed. Appalachians had significantly higher worry than non-Appalachians. Cancer type and lower need for cognition were associated with greater worry. Those with missing perc...
Chae, Jiyoung; Lee, Chul-joo; Jensen, Jakob D
The present study defined cancer information overload (CIO) as an aversive disposition wherein a person is confused and overwhelmed by cancer information, which occurs when he or she fails to effectively categorize new information due to a lack of resources for effective learning. Based on the definition and informed by previous studies on information overload and the cognitive mediation model, we hypothesized that low ability and motivation to process cancer information would lead to CIO. We used education level and trait anxiety as factors related to ability. Cancer history and the use of active media channels (such as the Internet and print media) were adopted as motivational factors. Four samples (three from the United States and one from South Korea) were used to explore the relationship between ability/motivation and CIO. Among them, only Sample 4 participants answered questions about stomach cancer, and other participants were asked about cancer in general. In all four samples, trait anxiety was positively associated with CIO. Health information use from active media channels (print or the Internet) was negatively associated with CIO in three samples. The associations between family history and CIO, and between education and CIO, were found in two samples. In short, the present study demonstrated that CIO partly depends on individual ability and motivation, thereby showing that CIO is influenced by personal characteristics as well as environmental factors. PMID:26512760
Full Text Available Although traditionally the primary information sources for cancer patients have been the treating medical team, patients and their relatives increasingly turn to the Internet, though this source may be misleading and confusing. We assess Internet searching patterns to understand the information needs of cancer patients and their acquaintances, as well as to discern their underlying psychological states. We screened 232,681 anonymous users who initiated cancer-specific queries on the Yahoo Web search engine over three months, and selected for study users with high levels of interest in this topic. Searches were partitioned by expected survival for the disease being searched. We compared the search patterns of anonymous users and their contacts. Users seeking information on aggressive malignancies exhibited shorter search periods, focusing on disease- and treatment-related information. Users seeking knowledge regarding more indolent tumors searched for longer periods, alternated between different subjects, and demonstrated a high interest in topics such as support groups. Acquaintances searched for longer periods than the proband user when seeking information on aggressive (compared to indolent cancers. Information needs can be modeled as transitioning between five discrete states, each with a unique signature representing the type of information of interest to the user. Thus, early phases of information-seeking for cancer follow a specific dynamic pattern. Areas of interest are disease dependent and vary between probands and their contacts. These patterns can be used by physicians and medical Web site authors to tailor information to the needs of patients and family members.
Jenkins, V; Fallowfield, L.; Poole, K
Aim—To conduct a commissioned survey of multidisciplinary breast team members' expectations of their own and each other's roles in providing different kinds of information to women with breast cancer.
Wallace, Rodrick; Wallace, Deborah; Robert G Wallace
'Racial' disparities among cancers, particularly of the breast and prostate, are something of a mystery. For the US, in the face of slavery and its sequelae, centuries of interbreeding have greatly leavened genetic differences between 'Blacks' and 'whites', but marked contrasts in disease prevalence and progression persist. 'Adjustment' for socioeconomic status and lifestyle, while statistically accounting for much of the variance in breast cancer, only begs the question of ultimate causali...
Alba-Ruiz, Ruben; Bermúdez-Tamayo, Clara; Pernett, Jaime Jiménez; Garcia-Gutierrez, Jose Francisco; Cózar-Olmo, José Manuel; Valero-Aguilera, Beatriz
Background: People who use the Internet to research health topics do not usually find all the information they need and do not trust what they read. This study was designed to assess the reliability, accessibility, readability, and popularity of cancer Web sites in Spanish and to analyze the suitability of Web site content in accordance with the specific information needs of cancer patients. Materials and Methods: This was a two-phase, cross-sectional, descriptive study. The first ph...
George Hripcsak; Rita Kukafka; Chung, Wendy K.; Casey Lynnette Overby
Personalized medicine is a model of healthcare that is predictive, personalized, preventive and participatory (“P4 Medicine”). Genetic counselors are an ideal group to study when designing tools to support cancer P4 Medicine activities more broadly. The goal for this work was to gain a better understanding of the information cancer genetic counselors seek from their patients to facilitate effective information exchange for discussing risk. This was an analysis of a qualitative data set from i...
Thorburn, Sheryl; Keon, Karen Levy; Kue, Jennifer
Despite low breast and cervical cancer screening levels among Hmong women in the U.S. reported in the literature, understanding of the barriers to screening for Hmong women is limited. Health literacy issues may influence screening behavior for this population. This qualitative study explored sources of information about breast and cervical cancer including screening and identified barriers to seeking such information for Hmong women and men. We conducted semi-structured, in-depth interviews ...
This page lists cancer drugs approved by the Food and Drug Administration (FDA) for ovarian cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.
Davis, Sharon Watkins; Fox, Laurie
Vincent DeVita, the director of the National Cancer Institute, has been promoting the use of the user-friendly cancer database system, Physician's Data Query (PDQ), both by physicians and by the public. Because on-line access to PDQ is limited to physicians or other qualified health care professionals, the Cancer Information Service, through its toll-free 1-800-4-CANCER telephone number, provides a major point of access to this system. This paper analyzes changes in the patterns of PDQ use ov...
Relationships among Internet health information use, patient behavior and self efficacy in newly diagnosed cancer patients who contact the National Cancer Institute's NCI Atlantic Region Cancer Information Service (CIS).
Fleisher, Linda; Bass, Sarah; Ruzek, Sheryl Burt; McKeown-Conn, Nancy
This NCI funded study examined the relationship between the use of Internet health information by people newly diagnosed with cancer (N=500), with patient task behavior and perceived self efficacy. Study variables were compared among Direct users of Internet health information (people using the Internet themselves), Indirect users of Internet health information (people receiving Internet health information from friends or family members), and Non-users of Internet health information (people not using the Internet or receiving health information from the Internet). The subjects were recruited from persons who called the Atlantic Region of the NCI's Cancer Information Service (CIS), located at Fox Chase Cancer Center in Philadelphia, PA. Follow up phone interviews were done with participants six weeks after initial contact to assess impact of the use of the Internet on perceived patient task behavior and self efficacy. Results show significant relationships between Internet use and all study variables. PMID:12463827
Lu, Shun; Yong-feng YU; Wen-xiang JI
The standardization of diagnosis and treatment of lung cancer has important significance for improving the prognosis of patients with lung cancer. A thorough and accurate interpretation of the guidelines of lung cancer is conducive to enhance a deeper understanding of the standardized diagnosis and treatment of lung cancer. The authors of this article intend to give a brief summary and comment for the latest information about diagnosis and treatment of lung cancer at home and abroad, focusing...
Full Text Available Objectives. Existing findings on cancer patients' use of information sources were synthesized to 1 rank the most and least used information sources and the most helpful information sources and to 2 find the impact of patient demographics and situations on use of information sources. Method. . To synthesize results found across studies, a systematic review was conducted. Medline and CINAHL were searched to retrieve literature on cancer patients' information source use. The retrieved articles were carefully selected according to predetermined criteria, and several articles were eliminated in a systematic approach. Analysis. The twelve articles that met the criteria were systematically analysed by extracting data from articles and summarizing data for the purpose of synthesis to determine the meaning of findings on most used information sources, least used information sources, most helpful information sources, effect of patient characteristics on preference for an information source, and effect of patient situations on preference for an information source. Results. In descending order of use, health care professionals, medical pamphlets, and family and friends were most used information sources. Internet and support groups were least used. In descending order of helpfulness, books, health care professionals and medical pamphlets were found to be most helpful information sources. Younger patients used health care professionals and certain forms of written information sources more than older patients. Conclusion. . The systematic review shows that many areas of cancer patients' information source use have been either neglected or barely analysed. An in-depth understanding of cancer patients' use of information sources and the characteristics in information sources they consider to be helpful is important for developing successful interventions to better inform patients.
Himes, Deborah O; Clayton, Margaret F; Donaldson, Gary W; Ellington, Lee; Buys, Saundra S; Kinney, Anita Y
The most common result of BRCA1/2 mutation testing when performed in a family without a previously identified mutation is an uninformative negative test result. Women in these families may have an increased risk for breast cancer because of mutations in non-BRCA breast cancer predisposition genes, including moderate- or low-risk genes, or shared environmental factors. Genetic counselors often encourage counselees to share information with family members, however it is unclear how much information counselees share and the impact that shared information may have on accuracy of risk perception in family members. We evaluated 85 sisters and daughters of women who received uninformative negative BRCA1/2 results. We measured accuracy of risk perception using a latent variable model where accuracy was represented as the correlation between perceived risk (indicators = verbal and quantitative measures) and calculated risk (indicators = Claus and BRCAPRO). Participants who reported more information was shared with them by their sister or mother about her genetic counseling session had greater accuracy of risk perception (0.707, p = 0.000) than those who reported little information was shared (0.326, p = 0.003). However, counselees shared very little information; nearly 20 % of family members reported their sister or mother shared nothing with them about her genetic counseling. Family members were generally not aware of the existence of a genetic counseling summary letter. Our findings underscore the need for effective strategies that facilitate counselees to share information about their genetic counseling sessions. Such communication may help their relatives better understand their cancer risks and enhance risk appropriate cancer prevention. PMID:26245632
Dellson, Pia; Nilbert, Mef; Carlsson, Christina
future simplified and more attractive informed consent forms. CONCLUSIONS: The emotional and cognitive responses to written patient information reported by patient representatives provides a basis for revised formats in future trials and add to the body of information that support use of plain language......, structured text and illustrations to improve the informed consent process and thereby patient enrolment into clinical trials....
Steven S. Coughlin, PhD
Full Text Available IntroductionThe number of people in the United States aged 65 years and older is increasing. Older people have a higher risk of dying from cancer; however, recent information about breast and colorectal cancer screening rates among women aged 65 years and older and about sources of health information consulted by these women is limited.MethodsWe examined data from the Health Information National Trends Survey for women aged 65 years and older who had no personal history of breast or colorectal cancer. Women whose self-reported race and ethnicity was non-Hispanic white, non-Hispanic black, or Hispanic were included in the analysis. The overall response rate for the 2003 survey was 34.5%.ResultsWomen aged 75 years and older had lower rates of recent mammography (mammogram in previous 2 years than did women aged 65 to 74 years. In both age groups, rates were especially low for Hispanic women and women with a household income of less than $15,000 per year. Rates of recent colorectal cancer screening (fecal occult blood test in previous year or endoscopy in previous 5 years were markedly lower for non-Hispanic black women aged 75 years and older than for other women in this age group, and for Hispanic women aged 65 to 74 years than for non-Hispanic women in this age group. Screening rates were lowest for women with an annual household income of less than $15,000, no family history of cancer, no usual health care provider, or 1 or no provider visits in the previous year.Differences were found in the groups’ preferred channel for receiving health information. Women who had had a mammogram in the previous 2 years were more likely to pay attention to health information on the radio or in newspapers and magazines than were women who had not received a recent mammogram. Women who had had a recent colorectal cancer screening test were more likely to pay attention to health information in magazines or on the Internet than were those who had not
McHugh, Seamus M
BACKGROUND: The internet is an important source of healthcare information. To date, assessment of its use as a source of oncologic information has been restricted to retrospective surveys. METHODS: The cancer-related searches of approximately 361,916,185 people in the United States and the United Kingdom were examined. Data were collected from two separate 100-day periods in 2008 and 2010. RESULTS: In 2008, there were 97,531 searches. The majority of searches related to basic cancer information (18,700, 19%), followed by treatment (8404, 9%) and diagnosis (6460, 7%). This compares with 179,025 searches in 2010 representing an increase of 183%. In 2008 breast cancer accounted for 21,102 (21%) individual searches, increasing to 85,825 searches in 2010. In 2010 a total of 0.2% (321) of searches focused on litigation, with those searching for breast cancer information most likely to research this topic (P=0.000). CONCLUSION: Use of the internet as a source of oncological information is increasing rapidly. These searches represent the most sensitive information relating to cancer, including prognosis and litigation. It is imperative now that efforts are made to ensure the reliability and comprehensiveness of this information.
Emotional and psychological distress is common among loved ones of cancer patients, who sometimes report more severe mental health issues than the patients themselves. In addition, many loved ones feel as though their information needs are not being met, which can lead them to seek out additional information online. This survey research examined the experiences of cancer patients' loved ones in viewing online content about the disease and the emotional outcomes of such browsing sessions. Participants (N = 191) were recruited from cancer- and caregiver-related nonprofits and online discussion boards. Results indicated that patients' loved ones were active users of online cancer Web sites. They primarily viewed and expressed a desire for information-based, rather than support-based, content. Many individuals desired in-depth treatment information, and those who viewed it had significantly more hope. Interestingly, multiple regression analysis revealed that viewing user-generated content was associated only with negative emotions, illustrating the potential dangers of social media spaces. Overall, this study shows the need for supporting patients' loved ones during their almost inevitable viewings of online cancer information. More research is needed in order to determine the best methods of mitigating potential negative effects of cancer Web sites and developing a useful online resource for this population. PMID:26636409
Anxiety Disorder; Cervical Cancer; Endometrial Cancer; Female Reproductive Cancer; Gestational Trophoblastic Tumor; Ovarian Epithelial Cancer; Ovarian Germ Cell Tumor; Sexual Dysfunction; Uterine Sarcoma; Vaginal Cancer; Vulvar Cancer
Bennenbroek, FTC; Buunk, BP; Stiegelis, HE; Hagedoorn, M; Sanderman, R; Van den Bergh, ACM; Botke, G; Buunk, Abraham (Bram)
The present study focused on the effects of social comparison information on subjective understanding of radiation therapy, validation of emotions, and self-efficacy of cancer patients undergoing radiation therapy. The effects of three different audiotapes, containing different kinds of social compa
Sankaranarayanan R; BM Nene; Dinshaw K; Rajkumar R; Shastri S; Wesley R; Basu P; Sharma R; Thara S; Budukh A; Parkin DM
India is a high-risk country for cervical cancer which accounts a quarter (126 000 new cases, 71 000 deaths around 2 000) of the world burden. The age-standardized incidence rates range from 16-55 per 100 000 women in different regions with particularly high rates in rural areas. Control of cervical cancer by early detection and treatment is a priority of the National Cancer Control Programme of India. There are no organized cytology screening programmes in the country. The technical and fina...
Full Text Available Obtaining complete medical record information can be challenging and expensive in breast cancer studies. The current literature is limited with respect to the accuracy of self-report and factors that may influence this. We assessed the agreement between self-reported and medical record breast cancer information among women from the Ontario site of the Breast Cancer Family Registry. Women aged 20–69 years diagnosed with incident breast cancer 1996–1998 were identified from the Ontario Cancer Registry, sampled on age and family history. We calculated kappa statistics, proportion correct, sensitivity, specificity, and positive and negative predictive values and conducted unconditional logistic regression to examine whether characteristics of the women influenced agreement. The proportions of women who correctly reported having received a broad category of therapy (hormone therapy, chemotherapy, radiation, or surgery as well as sensitivity and specificity were above 90%, and the kappa statistics were above 0.80. The specific type of hormonal or chemotherapy was reported with low-to-moderate agreement. Aside from recurrence, no factors were consistently associated with agreement. Thus, most women were able to accurately report broad categories of treatment but not necessarily specific treatment types. The finding of this study can aid researchers in the use and design of self-administered treatment questionnaires.
Dellson, Pia; Nilbert, Mef; Carlsson, Christina
of future simplified and more attractive informed consent forms. CONCLUSIONS: The emotional and cognitive responses to written patient information reported by patient representatives provides a basis for revised formats in future trials and add to the body of information that support use of plain language...
Heide, I. van der; Uiters, E.; Schuit, J.; Rademakers, J.; Fransen, M.
Making an informed decision about participation in colorectal cancer (CRC) screening may be challenging for invitees with lower health literacy skills. The aim of this systematic review is to explore to what extent the level of a person’s health literacy is related to their informed decision making
Pascal, J; Johnson, N; Dickson-Swift, V; McGrath, P; Dangerfield, F
The concept of receptivity is a new way of understanding the personal and social factors that affect a person living with and beyond cancer, and how these factors influence access to formal supportive care service provision and planning. This article contributes to new knowledge through applying the concept of receptivity to informal supportive cancer care in regional Australia. Literature indicates that a cancer diagnosis is a life-changing experience, particularly in regional communities, where survival rates are lower and there are significant barriers to accessing services. Heideggerian phenomenology informed the design of the study and allowed for a rich and nuanced understanding of participants lived experiences of informal supportive cancer care. These experiences were captured using in-depth interviews, which were subsequently thematically analysed. Nineteen participants were recruited from across regional Victoria, Australia. Participants self-reported a range of stages and types of cancer. Significantly, findings revealed that most participants were not referred to, and did not seek, formal supportive care. Instead, they were receptive to informal supportive care. Understanding receptivity and the role of anxiety and fear of death has implications for partners, family, community members, as well as professionals working with people with living with and beyond cancer. PMID:26047366
A summary is provided of the issues discussed at the climate change implications for water and ecological resources conference, and recommendations that came out of the conference. The objectives of the meeting were to present and discuss results of recent climate change experiments undertaken in Canada; evaluate a variety of climate models and impact analyses and to develop methods and strategies for future study; and to establish working linkages between modellers and analysts in the fields of climate, hydrology, and ecosystem research, as well as between social scientists and policy makers interested in the implications of climate change. Recommendations were made in the five areas of research, monitoring, risk assessment, policy and information dissemination. Additional research should be undertaken to foster improved understanding of relationships between climate, climate change, and ecological and human processes. A suitable monitoring program, including a national wetlands monitoring program, should be established. Risk assessments should be undertaken to evaluate vulnerabilities of ecosystem components, to assess options, and to provide the information required to develop and implement appropriate policy objectives. The impacts of a range of public policy responses and feedbacks should be assessed. The dissemination of well-targeted and accurate information is vital if basic societal attitudes regarding the value of water and ecosystems are to be changed
El-Subaihi, J.A.; Anton, François; Mioc, Darka; Andersen, S.V.; Lausen, B.
treatment processes, compensations to patients due to medical negligence and duplication of work and effort. In order to address a solution for healthcare practitioners, a small subgroup of patients and diseases is chosen from all chronic diseases. Namely, children diagnosed with cancer. This research...... brings the methodology for child cancer treatment plan that produces an ontology to create a conceptual model and a database model. To construct the ontology, the "methontology" method is used as a structured approach for the ontology process. The method guides the ontology developer from scratch to...... building a complete model. The ontology is developed in two phases. In the first phase, research from other countries and process models are reviewed and the generic model is built from this research. The generic model is adapted to the ontology for the Danish hospitals including the NOPHO-ALL 2008...
Romantan, Anca; Kelly, Bridget J.; Stevens, Robin S.; Gray, Stacy W.; Hull, Shawnika J.; Ramirez, A. Susana; Hornik, Robert C.
Little is known about how patients move among information sources to fulfill unmet needs. We interviewed 43 breast, prostate, and colorectal cancer patients. Using a grounded theory approach, we identified patterns and motivations for movement among information sources. Overall, patients reported using one source (e.g., newspaper) followed by the use of another source (e.g., Internet), and five key motivations for such cross-source movement emerged. Patients’ social networks often played a central role in this movement. Understanding how patients navigate an increasingly complex information environment may help clinicians and educators to guide patients to appropriate, high-quality sources. PMID:20204573
THORBURN, SHERYL; KEON, KAREN LEVY; KUE, JENNIFER
Despite low breast and cervical cancer screening levels among Hmong women in the U.S. reported in the literature, understanding of the barriers to screening for Hmong women is limited. Health literacy issues may influence screening behavior for this population. This qualitative study explored sources of information about breast and cervical cancer including screening and identified barriers to seeking such information for Hmong women and men. We conducted semi-structured, in-depth interviews with 84 Hmong women and men living in Oregon, USA. Interviews were audio-recorded and transcribed. Transcripts of 83 usable interviews were analyzed using content analysis. Health care providers and the Internet were the most frequently cited sources of information about breast and cervical cancer including screening. Other sources were family, friends, and other media. Over half of the participants indicated that nothing would prevent them from seeking information about these topics. These findings suggested that health care providers and the Internet may be important sources of information about breast and cervical cancer screening for Hmong women. Additional research is needed to examine further Hmong women’s health literacy needs and preferences with regards to breast and cervical cancer screening. PMID:23879458
Full Text Available Personalized medicine is a model of healthcare that is predictive, personalized, preventive and participatory (“P4 Medicine”. Genetic counselors are an ideal group to study when designing tools to support cancer P4 Medicine activities more broadly. The goal for this work was to gain a better understanding of the information cancer genetic counselors seek from their patients to facilitate effective information exchange for discussing risk. This was an analysis of a qualitative data set from interviews of eight cancer genetic counselors, recruited from three institutions. Genetic counselors at each site were interviewed using a semi-structured, open-ended questionnaire. A selective coding approach was used to determine major themes associated with genetic counseling information needs for communicating risk. We generated a model for understanding categories of genetic counseling information needs to support risk communication activities. Common activities for risk communication included risk assessment and tailoring communication. Categories of information needs included: (a clinical patient characteristics, (b social and cognitive patient characteristics and (c patient motivation and goals for the genetic counseling session. A logical next step is for this model to inform the design of software systems for pre-visit patient planning and delivering just-in-time educational information to facilitate cancer risk communication activities.
Beyraghi N; Mottaghipour Y; Mehraban A; Eslamian E; Esfahani F
Background: In the last decades cancer has become one of the important causes of death in Iran .This study examined perspective of a group of Iranian health professionals, patients and patients’ family members regarding their view on disclosure of cancer information at a university hospital in Tehran, Iran. Methods: The method of study was qualitative semi-structured focused group content analysis. Two group leaders (psychologist and psychiatrist) run the focus groups. Oncol...
Abrahamson, Kathleen, RN,MS
Kathleen Abrahamson1, Morgan Durham1, Rebekah Fox21Department of Public Health, Western Kentucky University, Bowling Green, KY, USA; 2Department of Communication, Texas State University, San Marcos, TX, USAAbstract: In this article, we synthesize current literature regarding the unmet needs of cancer patients, with a specific focus on interventions that address psychosocial distress, social support, and information deficits. Research indicates many patients diagnosed with cancer express unmet...
Morris, Melanie; Friedemann Smith, Claire; Boxell, Emily; Wardle, Jane; Simon, Alice; Waller, Jo
Background Provision of written information may improve awareness of cancer symptoms and encourage timely presentation in primary care. This study assessed changes in symptom knowledge, perceived barriers to help-seeking, anxiety and intention to seek help, following exposure to a leaflet to raise awareness of gynaecological cancer symptoms. Methods Women (N = 484) completed questionnaires before and after reading the leaflet. The primary outcome was change in anticipated time to help-seeking...
J. Jansen; Weert, J.C.M. van; Wijngaards-de Meij, L.; Van Dulmen, S.; Heeren, T. J.; Bensing, J M
Objectives: This study investigates information recall in unaccompanied and accompanied older cancer patients and their companions.Methods: One hundred cancer patients (aged >/=65 years) and 71 companions completed a recall questionnaire after a nursing consultation preceding chemotherapy treatment. Recall was checked against the actual communication in video-recordings of the consultations. Patients also completed measures of anxiety and memory-related beliefs.Results: Findings revealed that...
Lee PY; Chang TR
Pei-Yi Lee,1,2 Tsue-Rung Chang11Department of Nursing, MacKay Memorial Hospital, Taipei, Taiwan; 2Department of Nursing, MacKay Medical College, Taipei, TaiwanAbstract: Cancer case management provides consecutive care during the entire process through diagnosis to treatment and follow-up. We established an integrative information system with integration of the health information system. This integrative information system shortened the time spent on case screening, follow-up data management, ...
The Association Contract covers a range of research domains that are important to the Radiation Protection Research Action, especially in the areas 'Evaluation of Radiation Risks' and 'Understanding Radiation Mechanisms and Epidemiology'. Three research projects concentrate on radiation dosimetry research and two projects on the modelling of radiation carcinogenesis. The following list gives an overview on the topics and responsible scientific project leaders of the Association Contract: Study of radiation fields and dosimetry at aviation altitudes. Biokinetics and dosimetry of incorporated radionuclides. Dose reconstruction. Biophysical models for the induction of cancer by radiation. Experimental data for the induction of cancer by radiation of different qualities. (orig.)
Davey, H M; Butow, P N; Armstrong, B K
Cancer patients' preferences for written prognostic information independent of the clinical context have not previously been investigated. This study aimed to assist a state cancer organisation to provide information to patients by assessing patients' understanding of statistical information; eliciting their preferences for framing, content and presentation; and assessing the acceptability of a card sort for obtaining preferences. With the exception of conditional and relative survival, initial difficulties in understanding statistical concepts were improved with a plain language explanation. Analysis of the interview transcripts revealed that participants generally supported the provision of written information about survival in booklets and on the Internet. They wanted positive, relevant and clear information. Participants said that the use of, and preferences for, this information would be affected by a patient's age, time since diagnosis, ability to cope with having cancer and the perceived credibility of the information source. They found the card sort acceptable, saying it made the assessment of understanding and selection of preferences easy. This study has identified two fundamental, and sometimes conflicting, factors underlying patients' preferences: the communication of hope and the need to understand information it has also identified patient characteristics thought to influence preferences. These factors and characteristics need to be taken into account when developing written prognostic information for patients. PMID:14562016
Cohen, Martin H.; Cortazar, Patricia; Justice, Robert; Pazdur, Richard
The study that led to U.S. Food and Drug Administration approval of pemetrexed injection for maintenance treatment of patients with locally advanced or metastatic nonsquamous non-small cell lung cancer whose disease has not progressed after four cycles of platinum-based doublet induction chemotherapy is reviewed.
Full Text Available Abstract Background The internet has become a frequently used and powerful tool for patients seeking medical information. This information may not undergo the same quality consideration as the peer-review criteria for publication of information in a journal. The aim of this study is to assess the quality of internet sites providing information on the treatment of cervical cancer, with comparisons between the quality assessments made by an educated lay person and an expert in the field. Methods A search of the World Wide Web was made by a lay person to identify sites containing information on the treatment of cervical cancer. The credibility and accuracy of these sites was assessed using predefined criteria based on 'Criteria for Assessing the Quality of Health Information on the Internet' and accepted guidelines for the treatment of cervical cancer. The assessment was made independently and in duplicate by the lay reviewer and medical expert in order to allow comparison. Results 46 relevant websites were assessed. Only one site contained all the credibility and accuracy criteria, with a further website containing all the credibility criteria. The majority of sites, 38/46, were deemed easy to navigate. The agreement between lay person and expert was good with only 6 items in total changed by the expert. Conclusion This study clearly shows there is wide variation in quality of websites available to patients on the treatment of cervical cancer. Further research and consideration is needed on the effects of website information on gynaecological cancer patients and how steps can be made to insure the posting of good quality information.