canadian cancer statistics: Topics by WorldWideScience.org

Computed tomography colonography: the future of colon cancer screening

Colorectal cancer (CRC) is the most common cause of cancer death among Canadian non-smokers. Each year about 21,500 Canadians are diagnosed with CRC. Ninety percent of cases occur in people aged 50 years or older. An estimated 4,800 Canadian men and 4,100 Canadian women die each year from the disease. About 75% of all new CRC cases arise in people with no known risk factors. Computed tomography colonography (CTC), a cross-sectional imaging examination that permits complete structural examination of the colon, shows promise as a tool for CRC screening. This article reviews the rationale for CRC screening, currently recommended Canadian and American screening guidelines and screening tools, and current evidence supporting CTC as a CRC screening tool and its advantages over conventional screening methods. (author)

2008-10-15

2

Diagnosis and management of hepatocellular carcinoma: results of a consensus meeting of The Ottawa Hospital Cancer Centre

Colorectal cancer (CRC) is the most common cause of cancer death among Canadian non-smokers. Each year about 21,500 Canadians are diagnosed with CRC. Ninety percent of cases occur in people aged 50 years or older. An estimated 4,800 Canadian men and 4,100 Canadian women die each year from the disease. About 75% of all new CRC cases arise in people with no known risk factors. Computed tomography colonography (CTC), a cross-sectional imaging examination that permits complete structural examination of the colon, shows promise as a tool for CRC screening. This article reviews the rationale for CRC screening, currently recommended Canadian and American screening guidelines and screening tools, and current evidence supporting CTC as a CRC screening tool and its advantages over conventional screening methods. (author)

2008-10-01

3

No difference in antibody titers against xenotropic MLV related virus in prostate cancer cases and cancer-free controls

Hepatocellular carcinoma (hcc) is an uncommon tumour, but its incidence is increasing in Canada and elsewhere. Currently, there are no Canadian recommendations for diagnosis and treatment of...Full Text Available

2010-04-01

4

British Library Electronic Table of Contents (United Kingdom)

New ELISA assays were developed to measure immunoreactivity for XMRV. Antibody titers were measured in a cohort of prostate cancer cases and cancer free controls from the central United States. No statistically significant differences were observed in immunoreactivity between cases and controls for either the XMRV-env or the XMRV-gag antigen.

2011-01-01

5

Multiparametric Statistics

Association of brain cancer with dental x-rays and occupation in Missouri

Multiparametric Statistics

2007-01-01

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Prediction of breast cancer prognosis using gene set statistics provides signature stability and biological context

This investigation of a brain cancer cluster in Missouri used two approaches to investigate associations with potential risk factors. In a case-control study in a rural town, we interviewed surrogates of cases and controls about potential risk factors. We found a statistically significant positive association of brain cancer with reported exposure to dental x-rays. Occupation was not associated with the cluster in the rural town. In a standardized proportional mortality study for the state of Missouri, we calculated the observed and expected proportion of brain cancers by occupation and industry in Missouri decedents. We found that motor vehicle manufacturers, beauty shop workers, managers and administrators, elementary school teachers, and hairdressers and cosmetologists had significantly elevated proportions of brain cancer. Brain tumors are inconsistently associated with ...

1991-01-01

7

Radiation processing technology for cosmetics: a report on a canadian study

BackgroundDifferent microarray studies have compiled gene lists for predicting outcomes of a range of treatments and diseases. These have produced gene lists that have little overlap,...Full Text Available

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Statistical measure of association between smoking and lung cancer in Abakaliki, Ebonyi State Nigeria.

Short communications only.

1992-09-13

9

Prevention of lung cancer by remediation of residential exposure to radon daughters

The hazards of smoking in relation to lung cancer can never be over emphasized. In recent times shortly after Ebonyi State was created in 1996, the capital territory has increasingly been polluted by either quarry operators, motorcycle (Okada) riders or reckless cigarette smokers and bush burning. To investigate the havoc caused by all these on people, questionnaire was distributed among smokers and non smokers in various areas of specialization and habitations. In measuring the significance of association and the degree of association, a chi2 test and odds ratio method of analysis was employed. The result of the analysis showed that non-smokers do suffer lung cancer. It also revealed that the chances of a smoker to have lung cancer is 1.765 times higher than that of a non-smoker. Analysis also showed that lung cancer depends on age of smokers. It was later discovered that middle aged population are ...

2009-04-01

10

The United States Bonneville Power Administration (BPA), as part of an energy conservation programme in the states of Washington, Oregon, Idaho, Wyoming, and Montana, has collected over 36,000 residential radon concentration measurements. Data were collected between 1983 and 1989 with ambient {alpha} etched track dosemeters. Based on the linear risk coefficient from the BEIR IV report for lifetime lung cancer in smokers and non-smokers, numbers of lung cancer cases attributable to radon exposure were predicted. Numbers of baseline lung cancer cases and numbers of these that were preventable by remediation were also estimated. Remediation to 10 pCi.1{sup -1}, to 4 pCi.1{sup -1}, and to outdoor levels were considered. With vital statistics data, results were extrapolated to populations in the states represented by the BPA data. Costs of remediation were estimated. Results were evaluated in terms of cost ...

1991-01-01

11

Statistics at Square One

Nonequilibrium statistical mechanics

Statistics at Square One

2009-01-01

12

Approaches to enhancing the quality of drug therapy. A joint statement by the CMA and the Canadian Pharmaceutical Association. Canadian Medical Association.

Nonequilibrium statistical mechanics

2001-01-01

13

British Library Electronic Table of Contents (United Kingdom)

This joint statement was developed by the CMA and the Canadian Pharmaceutical Association, a national association of pharmacists, and includes the goal of drug therapy, strategies for collaboration...Full Text Available

1996-09-15

14

PurposeTo conduct a retrospective analysis within a large university teaching hospital, comparing outcomes between patients receiving either radical surgery or radiotherapy as curative treatment for bladder cancer.Patients and MethodsBetween March 1996 and December 2000, 169 patients were treated radically for muscle-invasive bladder cancer. Data were collected from patient notes. Statistical analyses were performed using Kaplan-Meier methods and Cox proportional hazards regression analysis to compare radiotherapy and surgical outcome data.ResultsThere was no difference in overall, cause-specific, and distant recurrence-free survival at 5 years between the two groups, despite the radiotherapy group being older (median age, 75.3 years vs. 68.2 years). There were 31 local bladder recurrences...

2008-01-01

15

Is exposure to silica associated with lung cancer in the absence of silicosis? A meta-analytical approach to an important public health question

British Library Electronic Table of Contents (United Kingdom)

Objective This report investigates epidemiologically whether exposure to silica is associated with lung cancer risks in individuals without silicosis. Methods We searched the PubMed reference data base from 1966 through 1/2007 for reports of lung cancer in silica-exposed persons without and with silicosis. To explore heterogeneity between studies, a multi-stage strategy was employed. First, fixed-effect summaries (FES) and corresponding 95% confidence intervals (CI) for various combinations of studies were calculated, weighting individual results by their precision. The homogeneity of the contributing results was examined using ?2 statistics. Where there was evidence of substantial heterogeneity, the CI around the FES was increased to take account of the between-study variability. Random-e...

2009-01-01

16

Rates of Advance in Infantry Division Attacks in the Normandy ...

NPD Canada's first nuclear power station

... breakthrough in Normandy), "Goodwood-Atlantic," and "Totalize" (British-Canadian operations) in the same campaign. It ...

1973-12-01

17

Risk of Colon Cancer and Coffee, Tea, and Sugar-Sweetened Soft Drink Intake: Pooled Analysis of Prospective Cohort Studies

This talk reviews the history of the Canadian nuclear-electric program highlighting Canada's first nuclear power station, the Nuclear Power Demonstration or NPD. NPD was commissioned and delivered electricity to Canadian consumers for the first time on june 4, 1962. The Canadian nuclear-electric program is based on the CANDU-PHW (Canadian Deuterium Uranium - Pressurized Heavy Water) concept which was conceived between 1955 and 1958 at the Chalk River Nuclear Laboratory (CRNL) of AECL, located a few miles from Deep River. This talk covers the history of the Canadian nuclear-electric activities dating back to 1939.

2002-07-01

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British Library Electronic Table of Contents (United Kingdom)

Background The relationships between coffee, tea, and sugar-sweetened carbonated soft drink consumption and colon cancer risk remain unresolved. Methods We investigated prospectively the association between coffee, tea, and sugar-sweetened carbonated soft drink consumption and colon cancer risk in a pooled analysis of primary data from 13 cohort studies. Among 731 441 participants followed for up to 6-20 years, 5604 incident colon cancer case patients were identified. Study-specific relative risks (RRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazards models and then pooled using a random-effects model. All statistical tests were two-sided. Results Compared with nonconsumers, the pooled multivariable relative risks were 1.07 (95% CI = 0.89 to 1.30, Ptrend = ...

2010-01-01

19

Diesel engine exhaust and lung cancer: An unproven association

Diagnosis of breast cancer with MR imaging using the magnetization transfer contrast and a newly-developed breast surface coil for the supine position

The risk of lung cancer associated with diesel exhaust has been calculated from 14 case-control or cohort studies. We evaluated the findings from these studies to determine whether there is sufficient evidence to implicate diesel exhaust as a human lung carcinogen. Four studies found increased risks associated with long-term exposure, although two of the four studies were based on the same cohort of railroad workers. Six studies were inconclusive due to missing information on smoking habits, internal inconsistencies, or inadequate characterization of diesel exposure. Four studies found no statistically significant association. It can be concluded that short-term exposure to diesel engine exhaust (20 years) increases the risk of lung cancer for locomotive engineers, brakemen, and diesel engine mechanics. There is inconsistent evidence on the effects of long-term exposure to diesel exhaust in the trucking industry. There is ...

1995-09-01

20

Sonography, Computed Tomography and ERCP in the diagnosis of focal exocrine pancreatic disease

We developed a new breast surface coil for the supine position. The subjects consisted of 9 patients with breast cancer varying from 46 to 60 years of age (average: 52). The cancer image of the SPGR (CE+) method was compared with that of the FSMTC (MTC-SPGR (CE+)) method and that of the FSMTC (MTC-SPGR with fat-saturation (CE+)) method in the sagittal section after injection of Gd-DTPA (0.1 mmol/kg). Quantitative analyses were performed before and after injection of Gd-DTPA in 6 patients. Three patients were excluded from the quantitative analyses owing to the clear detection of tumors in the fat tissue. Signal intensity measurements were systematically performed in each region of interest (ROI), i.e. the cancer lesion, the surrounding mammary gland. Statistical analyses showed significant differences between the lesions using the FSMTC (MTC-SPGR (CE+)), and the FSMTC (MTC-SPGR with fat-saturation ...

1998-09-01

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Genetic testing for hereditary cancer: Effects of alexithymia and coping strategies on variations in anxiety before and after result disclosure

In spite of the improved imaging techniques currently available, mortality for pancreatic cancer is still high, and pancreatics is often diagnosed only in its advanced stages. The authors investigated the value of different imaging techniques - i.e., US, CT, and ERCP - for an early diagnosis, when a more effective (curative?) treatment can be suggested. Fifty-six cases of pancreatic cancer and 36 cases of chronic pancreatitis were evaluated. The results indicate that ERCP, with the help of statistical methods, is superior to US and CT not only in evaluating early neoplastic or inflammatory lesions, but also for their differential diagnosis. In the letter case, ERCP can sometimes be used as a valid alternative to fine-needle aspiration biopsy.

1991-01-01

22

British Library Electronic Table of Contents (United Kingdom)

This study assessed the impact of the results of genetic testing for hereditary cancer from a multifactorial health psychology perspective, considering that emotional expression plays a key role in psychological adjustment. Measures of dispositional and transactional coping strategies, anxiety and alexithymia were filled out by 77 participants in a longitudinal study design. Statistical analyses were performed using general linear models and partial least squares path modelling, low-constraint methods that are particularly useful in the behavioural sciences. While anxiety levels prior to the result announcement were predictive of the distress experienced by noncarriers, considerable variability was observed for mutation carriers. Some subjects who had lower anxiety levels before the test d...

2011-01-01

23

Statistical modelling for social researchers principles and practice

Statistical Analysis of Designed Experiments

Statistical modelling for social researchers

2008-01-01

24

Essential Mathematics and Statistics for Science

Statistical Analysis of Designed Experiments

2010-01-01

25

Choosing and Using Statistics A Biologist's Guide

Essential Mathematics and Statistics for Science

2009-01-01

26

Applied Statistics for Civil and Environmental Engineers

Choosing and Using Statistics

2009-01-01

27

The benefits of low level radiation

Applied Statistics for Civil and Environmental Engineers

2009-01-01

28

The assumed linear relationship between exposure to radiation and cancer incidence is questioned in this article. The current research data on radiation effects at the cellular level is reviewed, as are epidemiological studies of background radiation effects and health effects of populations exposed to low levels of radiation exposure via employment or medical treatments. Statistics reveal that threshold levels currently in force need to be reviewed. Some evidence of beneficial effects of low level radiation exposure effects of low level radiation exposure is also presented, and so regulations should be reviewed at an international level. (UK).

1997-06-01

29

Thyroid cancer incidence

Thyroid cancer in the Ukraine

Short communication.

1992-11-12

30

Creation of the BioBank, Early Detection and Discovery Biomarkers

Short communication.

1995-06-01

31

The MonoPrep Pap test for the detection of cervical cancer and its precursors. Part I: results of a multicenter clinical trial.

Pancreatic Cancer; Head and Neck Cancer; Breast Cancer

2011-04-03

32

Cancer mortality among French atomic energy commission workers

The MonoPrep Pap Test (MPPT; MonoGen, Lincolnshire, IL) is a novel, liquid-based specimen collection and processing technology for cytologic and molecular testing. Its usefulness in the detection of cervical cancer and its precursors was evaluated in a multicenter, masked, adjudicated, split-sample study of 10,739 samples. After preparation of a conventional smear, the residuum on the collection device was rinsed into a collection vial from which an MPPT slide was prepared. Accuracy was assessed by masked reference interpretation by an independent pathologist. Slides prepared by MPPT, compared with smears, yielded statistically significant increases in relative sensitivity for atypical squamous cells of undetermined significance and worse, atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion/atypical glandular cells and worse, and low-grade squamous intraepithelial lesion and worse. There was no significant ...

2008-02-01

33

Application of 18F-fluorodeoxyglucose positron emission tomography to detection of proximal lesions of obstructive colorectal cancer

An analysis of the mortality of workers employed at the Commissariat a l'Energie Atomique (CEA) between 1946 and 1994 is presented. Standardized Mortality Ratios (SMR) are computed with reference to the French national population for the period 1968-1994. 51 286 workers are included in the study. 3 784 deaths occurred between 1968 and 1994. A healthy worker effect is observed for men (SMR=0.53 Cl{sub 90%}=[0.52; 0.55]) and for women (SMR=0.70 Cl{sub 90%}=[0.64; 0.76]). An excess is observed for male pleural cancers (SMR=1.54, Cl{sub 90%}=[1.03; 2.21]). An excess of breast cancer is observed among women, statistically significant for the 1980-1994 period (SMR=1.30, Cl{sub 90%}=[1.04; 1.61]). An excess is observed for malignant melanoma for both sexes (SMR=1.38, Cl{sub 90%}=[0.95; 1.96]), stronger for the 1990-1994 period (SMR=2.11, Cl{sub 90%}=[1.25; 3.34]). It diminishes with age. (orig.)

2000-07-01

34

Name techniques in Canada: current trends in utilization rates and recommendations for their inclusion at the Canadian Memorial Chiropractic College

In cases of obstructive colorectal cancer (CRC), preoperative diagnosis of the proximal lesion is often difficult when the primary lesion impedes the passage of the endoscope. The aim of this study was to evaluate the usefulness of fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET) in such cases. A total of 52 obstructive CRC patients who underwent preoperative FDG-PET and subsequent surgical resection were retrospectively reviewed. The correlation between characteristics of the proximal lesion and FDG-PET findings was analyzed statistically. There was a significant correlation between the proximal lesion size and the maximum standardized uptake value (P=0.00016). Abnormal FDG accumulation in the proximal colon indicated the existence of proximal cancer or adenoma with a sensitivity of 50% and a specificity of 100%. There was a significant difference in the distribution of tumor size between the cases ...

2010-10-01

35

Injuries at a Canadian National Taekwondo Championships: a prospective study

Since its establishment in 1945, the Canadian Memorial Chiropractic College (CMCC) has predominately adhered to a Diversified model of chiropractic technique in the core curriculum; however, many students...Full Text Available

2000-09-01

36

Does It Matter What You Measure? Neighbourhood Effects in a Canadian Setting

BackgroundThe purpose of this prospective study was to assess the injury rates in male and female adult Canadian Taekwondo athletes relative to total number of injuries, type and...Full Text Available

37

Canadian Emergency DepartmentTriage and Acuity Scale: implementation in a tertiary care center in Saudi Arabia

Data from 8,032 Manitoba respondents to the 1996/97 Canadian National Population Health Survey were linked to the 1996 census to study whether measures of morbidity, both self-reported and objectively...Full Text Available

2010-08-01

38

Current situation of steel industry and coking coal industry and expectations for Canadian coal

BackgroundThe Canadian Emergency Department Triage and Acuity Scale (CTAS) is a well recognized and validated triage system that prioritizes patient care by severity of illness....Full Text Available

39

Monitoring of DNA and cytogenetic damage in lymphocytes from persons with skin cancer diseases

The world steel industry and market and the current status and prospects for the Japanese steel industry are discussed with particular reference to China, Europe, and the US. Trends in coking coal supply from Australia, Canada, and Mongolia and changes in demand for hard and semi-soft coking coals are considered. Canadian coal plays a significant role in the hard coking coal and PCI coal markets. This is expected to continue. Emerging concerns include the strong Canadian dollar and increases in fuel and materials costs. Canadian suppliers are asked to improve efficiencies, be competitive in the overall coal chain, and diversify their PCI coal reserves. 14 figs.

2006-07-01

40

Future of the Japanese steel industry and a suggestion to the Canadian coal industry

There is a lot of interest in the studies that would help to understand whether there is a casual association between cancer and various types of molecular or cytogenetic damage detected in human cells. One major oncogenesis process is activation of proto-oncogenes by point mutations or chromosomal translocation. There are substantial evidence that indicates that the loss of heterozygosity of certain chromosomes is involved in human cancerogenesis. Our study aimed to elicit the possible association between cancer and DNA and cytogenetic abnormalities induced in lymphocytes of people bearing various categories of skin cancer cells. Fresh blood was collected by venipuncture from 25 individuals (including nine prior to cancer treatment). All patients were nonsmoking males, however 42.3 % of them were former smokers. Blood samples were divided into two parts and in the first part of samples cytogenetic ...

2004-11-01

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APPLICATION OF STATISTICAL METHODS IN WEATHER PREDICTION.

Discussion is presented of world crude steel production, the Japanese steel industry and its expectations of the Canadian coal industry. It is concluded that the Canadian coal industry should pay attention to the trend in customer's requirements regarding coal quality, maintain price competitiveness in the international market place, and remain flexible with regard to the market trend.

1989-01-01

42

Coffee and tea consumption and endometrial cancer risk in a population-based study in New Jersey

PMID:16589753

1955-11-15

43

British Library Electronic Table of Contents (United Kingdom)

We evaluated the role of tea and coffee and substances added (sugar/honey, creamers, and milk) on endometrial cancer risk in a population-based case?control study in six counties in New Jersey, including 417 cases and 395 controls. Multivariate odds ratios (OR) and 95% confidence intervals (CI) were computed using unconditional logistic regression. There was a moderate inverse association with coffee consumption, with an adjusted OR of 0.65 (95% CI: 0.36?1.17) for women who reported more than two cups/day of coffee compared to none. Tea consumption appeared to increase risk (OR: 1.93; 95% CI: 1.08?3.45), but after including the variables sugar/honey and cream/milk added to tea in the model, the risk estimate was attenuated and no longer statistically significant (OR: 1.77; 95% CI: 0.96?3.2...

2010-01-01

44

Analysis of heterogeneous cell populations: A density-based modeling and identification framework

British Library Electronic Table of Contents (United Kingdom)

Abstract: In many biological processes heterogeneity within clonal cell populations is an important issue. One of the most striking examples is a population of cancer cells in which after a common, identical death signal some cells die whereas others survive. The reason for this heterogeneity is intrinsic and extrinsic noise. In this paper we present a mechanistic multi-scale modeling framework for cell populations, in which the dynamics of every individual cell is captured by a parameter dependent stochastic differential equation (SDE). Heterogeneity among individual cells is accounted for by differences in parameter values, modeling extrinsic influences. Based on the statistical properties of the extrinsic noise and the SDE model for the individual cell, a partial differential equation (...

2011-01-01

45

Radiation Therapy in Treating Patients With Prostate Cancer

Prostate Cancer; Psychosocial Effects of Cancer and Its Treatment; Radiation Toxicity; Sexual Dysfunction and Infertility

2011-09-13

46

An evaluation of current methods of diagnosing colorectal cancer in the United Kingdom

Purpose: To conduct a retrospective analysis within a large university teaching hospital, comparing outcomes between patients receiving either radical surgery or radiotherapy as curative treatment for bladder cancer. Patients and Methods: Between March 1996 and December 2000, 169 patients were treated radically for muscle-invasive bladder cancer. Data were collected from patient notes. Statistical analyses were performed using Kaplan-Meier methods and Cox proportional hazards regression analysis to compare radiotherapy and surgical outcome data. Results: There was no difference in overall, cause-specific, and distant recurrence-free survival at 5 years between the two groups, despite the radiotherapy group being older (median age, 75.3 years vs. 68.2 years). There were 31 local bladder recurrences in the radiotherapy group (24 solitary), but there was no significant difference in distant recurrence-free survival. In a more ...

2008-02-01

47

"3H thymidine an indicator of benzo(a)pyrene induced lung carcinogenesis: role of quercetin and curcumin

Colorectal cancer (CRC) is a highly conversed topic, particularly since implementation of screening for CRC is imminent within the U.K. Aims: The aim of this research project was to examine the diagnostic tools currently used within the UK to detect CRC and their impact on the aetiology and epidemiology of CRC. Methodology: The complexity of the research topic lent itself towards a literature review. A systematic approach of researching was therefore adopted to analyse and critically evaluate the reliability and validity of articles. Electronic databases including AMED, Cancerlit, CINHAL, the Cochrane Library, EMBASE, MEDLINE and EBM-Reviews were utilised to provide a wide spectrum of recent and relevant articles. Other research strategies involved looking for books relating to the topics, which were kept to within 6 years of publication to maintain accuracy of information. Selected websites, such as NICE, the Department of Health, NHS websites and ...

2009-05-15

48

Thyroid cancer after Chernobyl; and reply

Full text: Lung cancer is responsible for most of the cancer related deaths and calls for new approaches to control the menace. In the present study chemopreventive efficacy of curcumin and quercetin was investigated against benzo(a)pyrene (BP) induced lung carcinogenesis. The mice were segregated into five groups which included normal control, BP treated, BP+curcumin treated, BP+quercetin treated and BP+curcumin+quercetin treated groups. The morphological and histological analyses of tumor nodules confirmed lung carcinogenesis, after 22 weeks of single i.p. injection of BP at a dose of 100 mg/Kg body weight to mice. Tumor incidence and tumor multiplicity were observed to be 88% and 1.75, respectively in the BP treated mice. A statistically significant increase in the uptake of "3H thymidine indicative of increased DNA synthesis which in turn is the marker of uncontrolled cancer cell proliferation, was ...

49

Surgical management of pancreatic cancer

Short communication.

1992-09-03

50

State Cancer Profiles Home Page

Full Text Available

2008-02-01

51

Childhood thyroid cancer in Belarus

Washington West Virginia Wisconsin Wyoming Cancer --- Choose a Cancer Site --- All Cancer Sites Bladder Brain & ONS Breast (Female) Breast (Female in situ) Cervix Childhood...

2011-10-15

52

An investigation into the profitability of energy management in office buildings

Short communication.

1992-10-22

53

Pain and self-reported health in Canadian children

This thesis examines the costs and benefits of energy management in office buildings and investigates the relationships between operating costs, space lease contracts, and building value. Energy management be building owners and managers begins with monitoring and analysing building energy, use and continues by reducing energy consumption through operating procedure changes, equipment replacement and control personnel training and continued monitoring. The cost to complete energy management projects in 12 British Columbia office buildings is analyzed. The average before-tax internal rate of return for the 12 energy management programs was 22.1% on total expenditures of Canadian $1.2 million. Nine of the buildings are owned and occupied by the provincial government, and the return on investment directly benefits the public. However, in the three prvately owned and tenant-occupied buildings, the owners have a less direct method of receiving the benefits due to net ...

1988-01-01

54

Nonmedical use of opioid analgesics among Ontario students

BACKGROUND:Despite increasing attention to the epidemiology of pain, relatively little is known about the association between pain and health in children. In particular, no studies...Full Text Available

2008-09-01

55

Statistical Inference, Econometric Analysis and Matrix Algebra

ABSTRACTOBJECTIVETo explore the prevalence and the demographic predictors of nonmedical use of opioid analgesics in the Canadian adolescent population.DESIGNData...Full Text Available

2010-03-01

56

Radiation epidemiological analysis of late effects of population exposure at northern part of east ural radioactive trace

Statistical Inference, Econometric Analysis and Matrix Algebra

2008-01-01

57

Activation of rapid signaling pathways and the subsequent transcriptional regulation for the proliferation of breast cancer MCF-7 cells by the treatment with an extract of Glycyrrhiza glabra root.

Population residing in the northern part of the Chelyabinsk oblast and the south eastern part of the Sverdlovsk oblast of Russia affected to accidental exposure since 1957. The territory (East Ural Radioactive Trace - EURT) was contaminated after explosion of container with highly radioactive wastes at the Mayak Production Association. Studies of health effects of exposure in the southern, head part of EURT are conducted in the Ural Research and Practical Center of Radiation Medicine (U.R.P.R.M.). In the 1990's U.R.P.C.R.M. formed a cohort of EURT within Chelyabinsk oblast (14,500 cases and 19,400 external controls). The cohort was followed in 1957-1987 and the results of the study are discussed by Crestinina et al. First results of study on exposure late health effects among rural population in the northern part of the EURT are presented in this paper. Firstly, or the period 1958-2000 a statistically significant increase in cancer ...

2006-07-01

58

Utilization of Fluorescent Microspheres and a Green Fluorescent Protein-Marked Strain for Assessment of Microbiological Contamination of Permafrost and Ground Ice Core Samples from the Canadian High Arctic

Glycyrrhiza glabra root is one of the common traditional Chinese medicines and used as flavoring and sweetening agents for tobaccos, chewing gums, candies, toothpaste and beverages. While glycyrrhizin is one of the main components in the extract of G. glabra root and has been characterized, the other components have not been well characterized. The mechanism of growth activation of breast cancer MCF-7 cells, including the activation of Erk1/2 and Akt, and the transcriptional regulation of estrogen-responsive genes, was examined by means of sulforhodamine B, luciferase reporter gene, real-time RT-PCR and Western blotting assays after the induction of the cells with the extract of G. glabra root. The extract has similar activity to that induced by 17beta-estradiol (E(2)), although glycyrrhizin did not show such an activity. Moreover, the estrogen receptor alpha-dependent neurite outgrowth induced by the extract was similar to that by E(2), whereas glycyrrhizin had no ...

2007-06-24

59

A legal-historical consideration of links between Canadian and South African racial policies

Fluorescent microspheres were applied in a novel fashion during subsurface drilling of permafrost and ground ice in the Canadian High Arctic to monitor the exogenous microbiological contamination of...Full Text Available

2005-02-01

60

British Library Electronic Table of Contents (United Kingdom)

Significant recent writings have suggested strong parallels and actual links between the historical legal architectures of Canadian Aboriginal policy and South African apartheid. This article's further probing of these claims shows them to be very doubtful. At the same time, some more limited legal parallels between the two systems shows the importance of undertaking further analysis of the transmission and exchange of legal ideas and norms within the Commonwealth order.

2010-01-01

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Off-road compression-ignition engine emission regulations under the Canadian Environmental Protection Act 1999 : guidance document

Off-road compression-ignition engine emission regulations under the Canadian Environmental Protection Act 1999 : guidance document

This guide explained the requirements for Off-Road Compression Ignition Engine Emission Regulations established under the Canadian Environmental Protection Act. The regulations are enforced by Environment Canada, which authorizes and monitors the use of the national emissions mark. The regulations prescribe standards for off-road engines that operate as reciprocating, internal combustion engines, other than those that operate under characteristics similar to the Otto combustion cycle and that use a spark plug or other sparking device. The regulations apply to engines that are typically diesel-fuelled and found in construction, mining, farming and forestry machines such as tractors, excavators and log skidders. Four different types of persons are potentially affected by the regulations: Canadian engine manufacturers; distributors of Canadian engines or machines containing Canadian engines; importers of ...

2006-03-15

62

Recent Reviews in Carcinogenesis 1981.

This guide explained the requirements for Off-Road Compression Ignition Engine Emission Regulations established under the Canadian Environmental Protection Act. The regulations are enforced by Environment Canada, which authorizes and monitors the use of the national emissions mark. The regulations prescribe standards for off-road engines that operate as reciprocating, internal combustion engines, other than those that operate under characteristics similar to the Otto combustion cycle and that use a spark plug or other sparking device. The regulations apply to engines that are typically diesel-fuelled and found in construction, mining, farming and forestry machines such as tractors, excavators and log skidders. Four different types of persons are potentially affected by the regulations: Canadian engine manufacturers; distributors of Canadian engines or machines containing Canadian engines; importers of ...

1999-01-01

63

Recent Reviews in Carcinogenesis is a service of the International Cancer Research Data Bank (ICRDB) Program of the National Cancer Institute, intended to facilitate and promote the exchange of information between cancer scientists. It contains abstracts ...

1982-01-01

64

Managing Cancer Pain

A case of Meigs syndrome mimicking metastatic breast carcinoma

Despite the existence of effective analgesic drugs, many cancer patients live and die with ineffective pain control. The control of cancer pain is largely achievable with the appropriate use of available...Full Text Available

1984-02-01

65

Statistical and Thermal Physics with Computer Applications, by Harvey Gould and Jan Tobochnik

BackgroundAdnexal masses are not uncommon in patients with breast cancer. Breast cancer and ovarian malignancies are known to be associated. In patients with breast cancer and co-existing...Full Text Available

66

Applied survey methods a statistical perspective

Not Available

2011-09-01

67

A review of Monte Carlo criticality calculations - convergence, bias, statistics

Applied survey methods

2009-01-01

68

OFFICE OF NEW DRUGS OFFICE OF PHARMACOEPIDEMIOLOGY AND STATISTICAL ...

No abstract prepared.

2008-01-01

69

Improved Mechanical Properties and Ozone Resistance of ...

... The pharmacologist/toxicologist and the statistician will jointly determine if a statistical review is needed and when the review should be done. ...

70

How to overestimate risks of ionizing radiations

... 31 5.4 FACTORIAL DESIGN STATISTICAL ANALYSIS..... ... resistance. o Factorial design statistical analysis gave the ...

1991-08-01

71

A review of conservatism for the Canadian exclusion area boundary calculation methodology

Ignoring the numerous, known and mainly unknown, interactions between chemicals and ionizing radiations, causes strong controversy about the risks of ionizing radiations. Yet the best known interactions between chemicals and radiations is that between radon and tobacco smoke. Although it is and it will be always impossible to derive quite quantitative laws for this interaction, it has been possible to derive some semi-quantitative relationships based on reasonable assumptions and statistics on lung cancer deaths in developed countries. They show that ignoring the dangers of tobacco smoking as we did still long after we had recognised the dangers of radiations, could asses to radiations thirty or forty times more risks than reality. As present world is flown by tens of thousands chemicals, little or not present in a natural environment, and as it would be very surprising that some hundreds of these do not behave like those contained in tobacco ...

72

[A giant ulcer of the stomach with perforation into the liver simulating cancer].

At present, two types of reactors, Pressurized Light Water Reactor(PLWR) and Pressurized Heavy Water Reactor(PHWR), are operating and under construction in Korea. They are much different in design concepts and inherent features from each other so that the calculation methods for Exclusion Area Boundary(EAB) are also different from each other. Thus, the domestic calculation methodology has been applied to PHWR, Wolsung 2, 3 and 4. In this report, the regulatory requirements and methodologies for EAB of Canadian methodology for EAB has been also investigated. It has been examined that the Canadian methodology which has been applied to the calculation of EAB of Wolsung 2, 3 and 4 can be said to be conservative enough compared to physical phenomena. 4 tabs., 3 figs., 22 refs. (Author).

1996-06-01

73

The Differential Expression of Aqueous Soluble Proteins in Breast Normal and Cancerous Tissues in Relation to Stage and Grade of Patients

PMID:9163165

1996-01-01

74

Sampling the Spatial Patterns of Cancer: Optimized Biopsy Procedures for Estimating Prostate Cancer Volume and Gleason Score

Breast cancer is a leading cause of female deaths worldwide. In Malaysia, it is the most common form of female cancer while Infiltrating ductal carcinoma (IDC) is the most common form of breast cancer....Full Text Available

2010-01-01

75

Permanent Brachytherapy of Localized Prostate Cancer: Preliminary Results

Prostate biopsy is the current gold-standard procedure for prostate cancer diagnosis. Existing prostate biopsy procedures have been mostly focusing on detecting cancer presence. However, they...Full Text Available

2009-08-01

76

Monitoring of Tumor Promotion and Progression in a Mouse Model of Inflammation-Induced Colon Cancer with Magnetic Resonance Colonography1

Full Text Available

2011-06-01

77

Modulation of MnSOD in Cancer: Epidemiological and Experimental Evidences

Early detection of precancerous tissue has significantly improved survival of most cancers including colorectal cancer (CRC). Animal models designed to study the early stages of cancer are valuable...Full Text Available

2009-03-01

78

Modulation of Benzene Metabolism by Exposure to Environment

Full Text Available

2010-06-01

79

Military workingn> dogs may be a sentinel for human cancer.

Lung Diseases; Cancer

2005-06-23

80

Current National Cancer Institute Center programs.

PMID:2348465

1990-06-20

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81

Change of telomerase activity in rectal cancer with chemoradiation therapy.

PMID:5017351

1972-04-01

82

A Feasibility Study of Smoking Cessation Program in Radiation Oncology

Full Text Available

2000-04-01

83

Regulation of Cancer-Causing Food Additives-Time for a ...

Cancer and Tobacco Abuse

2007-10-29

84

Radiation Therapy and Cisplatin With or Without Amifostine in Treating Patients With Stage IIIB or Stage IVA Cancer of the Cervix

... Accession Number : ADA145145. Title : Regulation of Cancer-Causing Food Additives-Time for a Change? Corporate Author ...

1981-12-11

85

Correlation of angiogenesis with "1"8F-FMT and "1"8F-FDG uptake in non-small cell lung cancer

Cervical Cancer; Radiation Toxicity

2011-09-09

86

A radiation hybrid map of the BRCA1 region of chromosome 17q12-q21

L-[3-"1"8F]-#alpha#-methyltyrosine ("1"8F-FMT) is an amino-acid tracer for positron-emission tomography (PET). We have conducted a clinicopathologic study to elucidate the correlation of angiogenesis with "1"8F-FMT and 2-["1"8F]-fluoro-2-deoxy-D-glucose ("1"8F-FDG) uptake in patients with non-small cell lung cancer (NSCLC). Thirty-seven NSCLC patients were enrolled in this study, and two PET studies with "1"8F-FMT and "1"8F-FDG were performed. Uptake of PET tracers was evaluated with standardized uptake value. Vascular endothelial growth factor (VEGF), CD31, CD34, L-type amino acid transporter 1 (LAT1) and Ki-67 labeling index of the resected tumors were analyzed by immunohistochemical staining, and correlated with the clinicopathologic variables and the uptake of PET tracers. The median VEGF rate was 45% (range, 10-78%). High expression was seen in 30 patients (81%, 30/37). VEGF expression was statistically associated with progressively ...

2009-04-01

87

Use of oral miltefosine for cutaneous leishmaniasis in Canadian soldiers returning from Afghanistan

The chromosomal region 17q12-q21 contains a gene (BRCA1) conferring susceptibility to early-onset familial breast and ovarian cancer. An 8000-rad radiation-reduced hybrid (RH) panel was constructed to provide a resource for long-range mapping of this region. A large fraction of the hybrids ([approximately]90%) retained detectable human chromosome 17 sequences. The complete panel of 76 hybrids was scored for the presence or absence of 22 markers from this chromosomal region, including 14 cloned genes, seven microsatellite repeats, and one anonymous DNA segment. Statistical analysis of the marker retention data employing multipoint methods provided both comprehensive and framework maps of this chromosomal region, including distance estimates between adjacent markers. The comprehensive RH map includes 17 loci and spans 179 cRays[sub (8000)]. Likelihood ratios of at least 1000:1 support the 10-locus framework order: cen-D17S250-ERBB2-(THRA1, ...

1993-09-01

88

The Optical Videodisc in Computer Based Education

Old world cutaneous leishmaniasis (CL) is caused by Leishmania major and Leishmania tropica, and is endemic to several Asian and Middle-Eastern countries where the...Full Text Available

2008-11-01

89

The Canadian Beef Industry

In a new approach to medical computer based education (CBE) students at several U.S. and Canadian health professions schools have been using an optical videodisc under computer control to study basic...Full Text Available

1984-11-07

90

Technology assessment and resource allocation for predictive genetic testing: A study of the perspectives of Canadian genetic health care providers

The cattle industry in Canada has changed greatly over the past several decades. Size of the national dairy herd has reduced steadily but this reduction has been more than offset by an increase in...Full Text Available

1980-02-01

91

Prevalence and determinants of pain and pain-related disability in urban and rural settings in southeastern Ontario

BackgroundWith a growing number of genetic tests becoming available to the health and consumer markets, genetic health care providers in Canada are faced with the challenge of developing...Full Text Available

92

Nutrient needs and feeding of premature infants. Nutrition Committee, Canadian Paediatric Society.

BACKGROUND:Canadian chronic pain prevalence estimates range from 11% to 66%, are affected by sampling and measurement bias, and largely represent urban settings.OBJECTIVES:To...Full Text Available

2006-01-01

93

Molecular and Kinetic Comparison of the Novel Extended-Spectrum ?-Lactamases CTX-M-25 and CTX-M-26

OBJECTIVE: To recommend appropriate intake of nutrients, food sources and feeding practices for premature infants. OPTIONS: Unfortified milk from the premature infant's own mother, fortified milk from...Full Text Available

1995-06-01

94

Medical fund took off like a rocket, but will budget bring it down to earth?

CTX-M-25 is a novel extended-spectrum β-lactamase isolated from a single Canadian Escherichia coli isolate. Susceptibility testing demonstrated that this enzyme confers resistance...Full Text Available

2004-12-01

95

Cordoba and Wolsung Projects: A Progress Report.

In 18 months the Canadian Medical Discoveries Fund (CMDF) has attracted investments worth $180 million to spend on biotechnology and medical research. Although eight initial investments totalled only...Full Text Available

1996-08-15

96

Canadian wind energy research and development status and perspectives

The Cordoba and Wolsung projects mark the entry into the international sales arena of the standardized Canadian 600 MWe CANDU-PHW reactor design. The Cordoba station experienced a setback in the early stages when severe inflation in Argentina led to a ren...

1977-01-01

97

Canadian infants' nutrient intakes from complementary foods during the first year of life

A general overview is provided of the Wind Energy Research and Development Program (WERD) structure, status, and current perspectives, and a highlight of recent achievements. The broad objectives of WERD are to: determine under what circumstances wind energy can make a viable contribution to Canadian energy supplies; establish the technology of wind energy conversion systems (WECS) to appropriate Canadian conditions; and to encourage and support Canadian industrial initiatives in the design and manufacture of WECS for both domestic and export markets. Field trials supported by WERD include: six small scale Savonius/Darrieus vertical axis wind turbines (VAWT) rated at 1 to 3 kW installed throughout Canada; a 37 kW VAWT mechanically coupled to a 50 kW diesel-electric set as part of a 100 kW remote community powerplant; five 50 kW grid-coupled VAWT generating systems; a 224 kW VAWT grid-coupled system in cooperation with Hydro ...

1983-05-01

98

Canada in the world power market

BackgroundComplementary feeding is currently recommended after six months of age, when the nutrients in breast milk alone are no longer adequate to support growth. Few studies have...Full Text Available

99

Benchmarking of refinery emissions performance : Executive summary

Canadian power and industrial projects world-wide are highlighted in this annual feature. A short section on the CANDU Wolsung Reactor in the Republic of Korea mentions that it went critical in November 1982 after taking only 60 months to complete.

1983-01-01

100

The regional control of the canadian energy production; Le contraste provincial de la production energetique canadienne

This study was undertaken to collect emissions performance data for Canadian and comparable American refineries. The objective was to examine parameters that affect refinery air emissions performance and develop methods or correlations to normalize emissions performance. Another objective was to correlate and compare the performance of Canadian refineries to comparable American refineries. For the purpose of this study, benchmarking involved the determination of levels of emission performance that are being achieved for generic groups of facilities. A total of 20 facilities were included in the benchmarking analysis, and 74 American refinery emission correlations were developed. The recommended benchmarks, and the application of those correlations for comparison between Canadian and American refinery performance, were discussed. The benchmarks were: sulfur oxides, nitrogen oxides, carbon monoxide, particulate, volatile ...

2003-01-01

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101

Refiners wrestle with air pollution

This document provides information and presents data on the energy situation in many regions of Canada. The first part deals with the petroleum and the bitumen shales of Alberta (reserves, exploitation and production, environmental impacts), the second part discusses with the hydroelectricity choice of Quebec and the 2004 crisis. The nuclear situation of Ontario is presented in the third part (nuclear park, programs, uranium reserves, research and development on Candu reactors), while the fourth part deals with the renewable energies (wind power and biomass). The canadian situation facing the Kyoto protocol is discussed in the last part. (A.L.B.)

2004-12-01

102

Thyroid cancer stem cells

Survey report: The Petroleum Association for the Conservation of the Canadian Environment is an organization of petroleum refiners that works closely with the Canadian government to set realistic air pollution control standards for refinery emissions. To date, the refiners have made a substantial investment in pollution abatement equipment. As a result, there have been no major pollution incidents traceable to refinery emissions. In the future, it will be essential that refiners continue to invest in air pollution abatement measures and continue to cooperate with the government in setting achievable pollution control standards. (1 photo, 1 table)

1980-01-01

103

British Library Electronic Table of Contents (United Kingdom)

Thyroid cancer is the most frequently diagnosed endocrine cancer and causes more deaths than all other endocrine cancers combined. Research findings support the concept that a subpopulation of thyroid cancer cells displays properties characteristic of stem cells. These putative cancer-forming entities drive tumorigenesis as a result of their dual ability to undergo self-renewal and to differentiate into various types of cancer cells; they also mediate metastasis and are resistant to the effects of chemotherapy and radiation therapy. This Review discusses the cellular origin of thyroid cancer and the properties of the thyroid cancer stem cell niche. The article critically evaluates the methods used to identify molecular markers expressed by thyroid-cancer-initiating cells and outlines prosp...

2011-01-01

104

Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation

British Library Electronic Table of Contents (United Kingdom)

Colorectal cancer is the second most common cause of cancer death in the world and about half of the patients with colorectal cancer require adjuvant therapy after surgical resection. Therefore, the eradication of cancer cells via chemotherapy constitutes a viable approach to treating patients with colorectal cancer. In this study, the effects of bufalin isolated from a traditional Chinese medicine were evaluated and characterized in HT-29 and Caco-2 human colon cancer cells. Contrary to its well-documented apoptosis-promoting activity in other cancer cells, bufalin did not cause caspase-dependent cell death in colon cancer cells, as indicated by the absence of significant early apoptosis as well as poly(ADP-ribose) polymerase and caspase-3 cleavage. Instead, bufalin activated an autophagy...

2011-01-01

105

Securing co-operation from persons supplying statistical data

Removal Sampling to Calculate Population Statistics

Securing the co-operation of persons supplying information required for medical statistics is essentially a problem in human relations, and an understanding of the motivations, attitudes, and behaviour...Full Text Available

1954-01-01

106

Predation and fragmentation portrayed in the statistical structure of prey time series

Removal Sampling is an easy-to-use Windows program which calculates population statistics from removal trapping experiment data. Using maximum likelihood methods it ... ...

107

Photon statistics of the free-electron--laser startup

BackgroundStatistical autoregressive analyses of direct and delayed density dependence are widespread in ecological research. The models suggest that changes in ecological factors...Full Text Available

108

Fermion-boson symmetry through superluminal transformations

We show that, for the high electron currents used in present-day free-electron lasers, spontaneous radiation is distributed according to thermal statistics.

1983-09-01

109

Advances in Statistical Methods for Substance Abuse Prevention Research

We consider the Pauli theorem on the spin-statistics connection for faster-than-light particles. As the consequence of the unlocalizability of tachyons in space we conclude that their spin-statistics correlations are inverted.

1985-08-01

110

Treatment with LL-37 Peptide Enhances Antitumor Effects Induced by CpG Oligodeoxynucleotides Against Ovarian Cancer

The paper describes advances in statistical methods for prevention research with a particular focus on substance abuse prevention. Standard analysis methods are extended to the typical research...Full Text Available

2003-09-01

111

Red and Processed Meat and Colorectal Cancer Incidence: Meta-Analysis of Prospective Studies

AbstractThere is an urgent need for innovative therapies against ovarian cancer, one of the leading causes of death from gynecological cancers in the United States. Immunotherapy employing...Full Text Available

2009-04-01

112

Quality-of-Life and Surgical Treatments for Rectal Cancer-a Longitudinal Analysis Using the California Cancer Registry

BackgroundThe evidence that red and processed meat influences colorectal carcinogenesis was judged convincing in the 2007 World Cancer Research Fund/American Institute of Cancer...Full Text Available

113

Prognostic features and markers for testicular cancer management

BackgroundHeterogeneous results for research investigating health-related quality of life (HRQL) in patients undergoing sphincter-ablating procedures for rectal cancer...Full Text Available

2010-08-01

114

Preliminary Evaluation of Psychoeducational Support Interventions on Quality of Life in Rural Breast Cancer Survivors Post-Primary Treatment

Testicular neoplasm accounts for about 1% of all cancers in men. Over the last 40 years, the incidence of testicular cancer has increased in northern European male populations for unknown reasons. When...Full Text Available

2010-01-01

115

Oral cancer awareness amongst hospital nursing staff: a pilot study

While most cancer survivors are at risk for being lost in the transition from treatment to survivorship, rural breast cancer survivors face special challenges that might place them at particular...Full Text Available

2009-01-01

116

Molecular conservation of estrogen-response associated with cell cycle regulation, hormonal carcinogenesis and cancer in zebrafish and human cancer cell lines

BackgroundOral cancer is as prevalent as cervical and testicular cancer in the United Kingdom. Nursing staff provide the oral health care for the patient population in hospital....Full Text Available

117

Minimally invasive surgery for rectal cancer: Are we there yet?

BackgroundThe zebrafish is recognized as a versatile cancer and drug screening model. However, it is not known whether the estrogen-responsive genes and signaling pathways that are...Full Text Available

118

Metagenes Associated with Survival in Non-Small Cell Lung Cancer

Laparoscopic colon surgery for select cancers is slowly evolving as the standard of care but minimally invasive approaches for rectal cancer have been viewed with significant skepticism. This procedure...Full Text Available

2011-02-21

119

Knowledge and Awareness about Cervical Cancer and Its Prevention amongst Interns and Nursing Staff in Tertiary Care Hospitals in Karachi, Pakistan

NSCLC (non-small cell lung cancer) comprises about 80% of all lung cancer cases worldwide. Surgery is most effective treatment for patients with early-stage disease. However, 30%–55% of these...Full Text Available

120

Immortalizing the Complexity of Cancer Metastasis Genetic Features of Lethal Metastatic Pancreatic Cancer Obtained from Rapid Autopsy

Background and ObjectiveCervical cancer is one of the leading causes of morbidity and mortality amongst the gynecological cancers worldwide, especially in developing countries. It...Full Text Available

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121

High-Risk Populations Identified in Childhood Cancer Survivor Study Investigations: Implications for Risk-Based Surveillance

The virtual lack of well-characterized metastatic pancreatic cancer tissues for study has limited systematic studies of the metastatic process of this deadly disease. To address this important...Full Text Available

2005-05-01

122

Frequency of ocular metastases in patients dying of cancer in eye bank populations.

Childhood cancer survivors often experience complications related to cancer and its treatment that may adversely affect quality of life and increase the risk of premature death. The purpose of this...Full Text Available

2009-05-10

123

Fecal microRNAs as novel biomarkers for colon cancer screening

AIMS: To examine the frequency of intraocular metastases in patients who had died of cancer, in an eye bank and necropsy population sample. METHODS: The first group included 302 cancer cases received...Full Text Available

1996-02-01

124

Excessive Soft Tissue Reaction after Stereotactic Body Radiation Therapy in a Woman with Four Different Cancer Diagnoses

IntroductionColorectal cancer (CRC) is the second leading cause of cancer-related deaths, but currently available non-invasive screening programs have achieved only...Full Text Available

2010-07-01

125

Epidemiologic studies of electric and magnetic fields and cancer: strategies for extending knowledge.

Patients experiencing several cancers can be a challenge, as optimal treatment options for the different cancers might interfere with each other. In this case report, we present a woman diagnosed with...Full Text Available

126

Customizing systemic therapy in patients with advanced non-small cell lung cancer

Epidemiologic research concerning electric and magnetic fields in relation to cancer has focused on the potential etiologic roles of residential exposure on childhood cancer and occupational exposure...Full Text Available

1993-12-01

127

Current practices in spatial analysis of cancer data: data characteristics and data sources for geographic studies of cancer

Lung cancer is the leading cause of cancer deaths worldwide. Standard chemotherapy has been shown to improve quality of life and has a modest influence on overall survival. This modest improvement in...Full Text Available

2011-07-01

128

Colorectal Cancer Association of Canada consensus meeting: raising the standards of care for early-stage rectal cancer

The use of spatially referenced data in cancer studies is gaining in prominence, fueled by the development and availability of spatial analytic tools and the broadening recognition of the linkages between...Full Text Available

129

Change in HER-2/neu Status from Negative to Positive following Treatment in Breast Cancer: A Case Report

The purpose of the meeting reported here was to develop a set of national evidence-based standards for assessing and managing patients with potentially resectable rectal cancer. This report represents...Full Text Available

2009-12-01

130

Breast Cancer Stem-Like Cells Are Inhibited by a Non-Toxic Aryl Hydrocarbon Receptor Agonist

IntroductionApproximately 25–30% of breast cancers are assumed to be HER-2/neu positive. It is well known that HER-2/neu-positive cancers after treatment with trastuzumab...Full Text Available

131

An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer

BackgroundCancer stem cells (CSCs) have increased resistance to cancer chemotherapy. They can be enriched as drug-surviving CSCs (D-CSCs) by growth with chemotherapeutic drugs, and/or...Full Text Available

132

An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer

Cancers are highly heterogeneous and contain many passenger and driver mutations. To functionally identify tumor suppressor genes relevant to human cancer, we compiled pools of short harpin...Full Text Available

2008-11-28

133

Alcoholic Beverages and Prostate Cancer in a Prospective US Cohort Study

BackgroundGenomics has substantially changed our approach to cancer research. Gene expression profiling, for example, has been utilized to delineate subtypes of cancer, and facilitated...Full Text Available

134

Despite numerous investigations, the correlation between alcohol consumption and prostate cancer risk remains uncertain. This report investigated the association between alcohol use and prostate cancer...Full Text Available

2010-10-01

135

Acne, dairy and cancer

A DNA transposon-based approach to validate oncogenic mutations in the mouse

A potent link to dairy seems to exist for three hormone-responsive glands. Acne, breast cancer and prostate cancer have all been linked epidemiologically to dairy intake. Although mechanisms postulated...Full Text Available

2009-01-01

136

Large-scale cancer genome projects will soon be able to sequence many cancer genomes to comprehensively identify genetic changes in human cancer. Genome-wide association studies have also identified...Full Text Available

2008-12-16

137

Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer

... York, 7/15/2008) Cancers Adrenal Gland Cancer Laparoscopic Adrenalectomy (Shawnee Mission Medical Center, Shawnee Mission, KS, ... MN, 1/24/2007) Colorectal Cancer Advances in Laparoscopic Colorectal Surgery (Charles E. Schmidt College of Biomedical ...

138

DEFF Research Database (Denmark)

Purpose Cisplatin plus gemcitabine is a standard regimen for first-line treatment of advanced non-small-cell lung cancer (NSCLC). Phase II studies of pemetrexed plus platinum compounds have also shown activity in this setting. Patients and Methods This noninferiority, phase III, randomized study compared the overall survival between treatment arms using a fixed margin method (hazard ratio [HR] < 1.176) in 1,725 chemotherapy-naive patients with stage IIIB or IV NSCLC and an Eastern Cooperative Oncology Group performance status of 0 to 1. Patients received cisplatin 75 mg/m(2) on day 1 and gemcitabine 1,250 mg/m(2) on days 1 and 8 (n = 863) or cisplatin 75 mg/m(2) and pemetrexed 500 mg/m(2) on day 1 (n = 862) every 3 weeks for up to six cycles. Results Overall survival for cisplatin/pemetrexed was noninferior to cisplatin/ gemcitabine (median survival, 10.3 v 10.3 months, respectively; HR = 0.94; 95% CI, 0.84 to 1.05). Overall survival was ...

2008-01-01

139

Toward a theory of the initiation of cancer by ionizing radiation: the twin doublet pair model

The Challenges of Colorectal Cancer Survivorship

Models are proposed which explain the mechanism of action on a molecular level for the initiation of cancer by electrons or alpha particles. (ACR)

1980-01-01

140

Role of Positron Emission Mammography (PEM) Flex Solo II Positron Emission Tomography (PET) Scanner in Evaluating Neoadjuvant Chemotherapy Response in Patients With Breast Cancer

With advances in treatment, colorectal cancer is being transformed from a deadly disease to an illness that is increasingly curable. With this transformation has come increased interest in the...Full Text Available

2009-09-01

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141

Role of Obesity in Prostate Cancer Development

Breast Cancer

2011-06-14

142

Reducing the Cancer Burden of Lifestyle Factors: Opportunities and Challenges of the Internet

... estrogen receptor status. Cancer Lett., 253, 291-300. 39. Xin,X ... and resistant mice. Brain Res.Bull., 52, 235-242. 40. Foster,BA ...

2011-04-01

143

Prognostic Indicators of Surgery for Esophageal Cancer: A 5 Year Experience

This paper focuses on the Internet as a tool for enhancing behavior and lifestyle changes to reduce the burden of cancer at a population level. The premise of this paper is that the Internet...Full Text Available

144

Localised breast cancers may have systemic influences on skin and hair

Background/Aim:To assess the prognostic indicators preoperatively presenting and influencing the mortality rate following esophagectomy for esophageal cancer.Full Text Available

2010-10-01

145

Laparoscopic surgery for rectal cancer: The state of the art

HypothesisBiomarkers, commonly expressed in breast cancer cells, may be correlated with their expression in breast skin of the same subjects.MethodsThe...Full Text Available

2007-02-01

146

Humoral BMP-2 is Sufficient for Inducing Breast Cancer Microcalcification

At present time, there is evidence from randomized controlled studies of the success of laparoscopic resection for the treatment of colon cancer with reported smaller incisions, lower morbidity rate...Full Text Available

2010-09-27

147

EFFECT OF ANATOMIC MOTION ON PROTON THERAPY DOSE DISTRIBUTIONS IN PROSTATE CANCER TREATMENT

Microcalcifications are an important diagnostic marker for breast cancer on mammograms, yet the mechanism of their formation is poorly understood. Indeed, there is presently no short-latency,...Full Text Available

2008-01-01

148

Dietary Lipids, Cells Adhesion and Breast Cancer Metastasis

PurposeTo determine the dosimetric impact of inter-fraction anatomical movements in prostate cancer patients receiving proton therapy.Full Text Available

2007-02-01

149

Diabetes and risk of incident colorectal cancer in a prospective cohort of women

... Accession Number : ADA396364. Title : Dietary Lipids, Cells Adhesion and Breast Cancer Metastasis. Descriptive Note : Annual rept. ...

2000-10-01

150

DNA Hypermethylation Patterns Detected in Serum as a Tool ...

ObjectiveTo determine whether accounting for the time dynamics of diabetes exposure will change the risk estimates for colorectal cancer.Full Text Available

2010-08-01

151

Content analysis of cancer blog posts*

... Grant support: National Cancer Institute Center grant CA 16087 and National Cancer Institute grant CA091892, Department of Defense grant ...

2009-09-01

152

Cancer cells cause vascular endothelial cell (vEC) retraction via 12(S)HETE secretion; the possible role of cancer cell derived microparticle.

Objectives:The efficacy of user-defined subject tagging and software-generated subject tagging for describing and organizing cancer blog contents was explored.Methods:The...Full Text Available

2009-10-01

153

Cancer as a metabolic disease

PMID:17103063

2006-11-12

154

Cancer Patients' Self-Reported Attitudes About the Internet

Emerging evidence indicates that impaired cellular energy metabolism is the defining characteristic of nearly all cancers regardless of cellular or tissue origin. In contrast to normal cells, which...Full Text Available

155

CDC - Cancer - NPCR - Registry Plus(tm) Software Programs for...

Background Increasing numbers of cancer patients are using the Internet, but little is known about their attitudes toward online health care.Full Text Available

156

CDC - Cancer - NPCR - NPCR-EDITS Technical Support

Malignancies Breast Malignancies Bladder, Prostate, and Testicular Malignancies Uses of Cancer Registry Data Brain Tumor Reporting Training Materials Overview Presentation and...

2011-10-15

157

CDC - Cancer - NPCR - NPCR-EDITS Downloads

Malignancies Breast Malignancies Bladder, Prostate, and Testicular Malignancies Uses of Cancer Registry Data Brain Tumor Reporting Training Materials Overview Presentation and...

2011-10-15

158

Breast cancer in the elderly.

Malignancies Breast Malignancies Bladder, Prostate, and Testicular Malignancies Uses of Cancer Registry Data Brain Tumor Reporting Training Materials Overview Presentation and...

2011-10-15

159

Anxiety and Cancer Treatment: Response to Stressful Radiotherapy

Breast cancer in the elderly has attracted considerable interest in recent years for three main reasons. Firstly, information concerning the profile (clinical and biological) of the disease in the geriatric...Full Text Available

1995-11-01

160

Adaptive Radiation for Lung Cancer

Previous research with individuals undergoing surgery or diagnostic procedures provided a conceptual framework for analysis of radiation therapy, a common form of cancer treatment. The present...Full Text Available

1984-01-01

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161

Adaptive Management of Liver Cancer Radiotherapy

The challenges of lung cancer radiotherapy are intra/inter-fraction tumor/organ anatomy/motion changes and the need to spare surrounding critical structures. Evolving radiotherapy technologies, such...Full Text Available

2011-01-01

162

Abnormal chromosome repair and risk of developing cancer.

Adaptive radiation therapy for liver cancer has the potential to reduce normal tissue complications and enable dose escalation, allowing the potential for tumor control in this challenging site....Full Text Available

2010-04-01

163

A Dose- and Time-Controllable Syngeneic Animal Model of Breast Cancer Microcalcification

Several scientists have proposed that DNA repair deficiencies and the induction of a mutator phenotype are responsible for the generation of multiple mutagenic alterations in cancer cells. I propose...Full Text Available

1993-10-01

164

US/Japan workshop on global change land disposal of CO{sub 2}

IntroductionThe development of novel diagnostic agents for the detection of breast cancer microcalcifications requires a reliable animal model. Based on previous...Full Text Available

2010-07-01

165

The Thai-Canadian nuclear human resources development linkage project

The general responses proposed to reduce CO{sub 2} emissions to the atmosphere are conservation, improved efficiency and fuel substitution. These are valid options but other alternatives such as CO{sub 2} capture and disposal may be more attractive for specific areas. There are good reasons why the capture and disposal option fits the situation in Western Canada. The first and obvious reason is the importance of hydrocarbon energy to the regional economy. Here the economy is based on the production, utilization and sale of hydrocarbons such as coal, oil and natural gas and we intend to stay in business. Besides meeting the Canadian demand, natural gas from Alberta is used in the US as far away as Boston and Los Angeles. Canadian heavy crude oil serves much of the American Midwest and coal from the Canadian Rocky Mountains is exported to Japan. Although many may consider these hydrocarbon reserves and fossil fuel production ...

1993-12-31

166

Heated lipiodol as an embolization agent for transhepatic arterial embolization in VX2 rabbit liver cancer model

The Thai-Canadian Nuclear Human Resources Development Linkage Project (the ''Project'') was initiated in 1994 in order to develop the engineering and scientific expertise needed for Thailand to decide whether and how the country can best benefit from the establishment of a nuclear power program. The Project was designed to upgrade current academics and people in industry, and to develop an adequate supply of new technical personnel for academic, industry, utility, regulatory and other government institutions. The key Project objectives included the establishment of a Chair in Nuclear Engineering at Chulalongkorn University, the upgrading of the current Masters level curriculum, the establishment of undergraduate and doctorate level curricula, development and delivery of an industrial training program for people in industry and government, exchanges of Thai and Canadian academics and industry experts to ...

1998-07-01

167

The present status of the Japanese steel industry and our expectations for Canadian coal

Purpose: To evaluate the therapeutic effect of heated (60 deg. C) lipiodol via hepatic artery administration in a rabbit model of VX2 liver cancer. Materials and methods: Thirty male New Zealand white rabbits were randomly divided into three groups with 10 rabbits assigned to each group. VX2 carcinoma cells were surgically implanted into the left hepatic lobe. The tumors were allowed to grow for 2 weeks, and studies were performed until the diameter of the tumors detected by ultrasonograph reached 2-3 cm. Under anesthesia, trans-catheter hepatic arterial embolization was performed and doxorubicin-lipiodol (37 deg. C) (1 mL), lipiodol (60 deg. C) (1 mL) or control (physiological saline (37 deg. C) (1 mL)) solution was injected into the hepatic arteries of animals in the three groups. One week later, the volume of the tumor was measured by ultrasonograph again. The serum of all rabbits was collected before injection and at 4 and 7 days after injection, and the level ...

2010-02-15

168

Sustainable development at Canadian Electrolytic Zinc -- recent improvements

The current status and prospects for Japan`s economy and steel industry, forecast for demand and supply of coking coal, directions in steel making technology, and Japan`s expectations for Canadian coal are discussed. The PCI system, the Coal Moisture Control System (CMC) to increase coke density before it is fed into coke ovens, a feeder that allows use of lower quality coke on the outskirts of blast furnaces, the Direct Iron Ore Smelting (DIOS) Process, and the `Next Generation Coke Oven`, where coke is heated rapidly and coked at 700-800{degree}C are considered. By 2000, semi-soft coking coals are expected to account for over half of total coal consumption by Japanese steel mills.

1995-09-01

169

Support required from Canada in the operation and maintenance of CANDU stations overseas

A series of modifications which increased the capacity of Canadian Electrolytic Zinc's Valleyfield plant from 220,000 MT/year to 260,000 MT/year during the last decade is discussed, combined with an an overview of the plant's operations. The modifications included modernisation of the waste disposal methods and facilities, such as a new high-density sludge wastewater treatment process, a new process to remove selenium from weak acid solutions and the jarofix process. Roasting capacity also has been improved by recent investments in new cooling coils, rebricking, oxygen enrichment and process automation. In addition to increases in refining capacity, the improvements also enabled the company to minimize its impact on the environment and the community.

2001-07-01

170

Impact of the regulation on information about new substances derived from the Canadian Environmental Protection Act (CEPA) on the application of biotechnological treatment of AMD : a case study; Impact du reglement sur les renseignements concernant les substances nouvelles de la LCPE sur l'application d'une biotechnologie de traitement du DMA : etude de cas

The long-term support required from Canada in the operation and maintenance of overseas CANDU nuclear generating stations after commercial operation has commenced is described, with reference entirely to the KANUPP reactor. This includes: technical support to station staff to increase plant reliability and maintainability; assistance with plant improvements; procurement of spares and consumables; and assistance with training programmes. This technical support may be provided by a small number of Canadian staff actually resident at the power station; by short-term visits of Canadian specialists to site and by technical and procurement services provided from Canada. Examples of technical problems experienced are given, showing typical services required from Canada.

171

Canadian fuel development program in 1997/98

This poster presentation covered a number of issues related to the new regulations concerning information on new substances derived from the Canadian Environmental Protection Act (CEPA). The authors described the background, and the objectives of the research project. A brief overview of the Acid Mine Drainage (AMD) process was provided, as well as the sulphate reduction process. The general methodology was explained, and the results of the bioactivation presented. The process followed for the bioaugmentation and the results obtained were presented. The regulations concerning information on new substances derived from the CEPA were described. The authors then presented their conclusions and perspectives. 26 figs.

2000-07-01

172

Canadian R&D on oil-fired combustion systems

This paper describes the CANDU fuel development activities in Canada during 1997 through 1998. The activities include those of the Fuel Technology Program sponsored by the CANDU Owners Group. The goal of the Fuel Technology Program is to maintain and improve the reliability, economics and safety of CANDU fuel in operating reactors. These activities, therefore, concentrate on the present designs of 28-element and 37-element fuel bundles. The Canadian fuel development activities also include those of the Advanced Fuel and Fuel Cycle Technology Program at AECL. These activities concentrate on the development of advanced fuel designs and advanced fuel cycles, which among other advantages, can reduce the capital and fuelling costs, maintain operating margins in aging reactors, improve natural-uranium utilization, and reduce the amount of spent fuel. (author)

1997-09-21

173

An introduction to climate change: a Canadian perspective

This paper describes research and development presently being conducted on oil-fired space and tap water heating systems by the Advanced Combustion Technology Group, CCRL/ERL/CANMET, in Ottawa, Canada. The presentation will focus on R&D activities at CCRL in support of the Canadian Oil Heat Association (COHA) and of the energy policy initiatives of Natural Resources Canada. Progress will be reported on activities to develop suitable oil-fired integrated systems to satisfy the low energy demands of new homes. The utilization of fuzzy logic-based control heating systems including fan coils for a complete range of old and new North American housing will be discussed. Additional activities to be discussed in the presentation will relate to the development of appropriate seasonal efficiency standards for complex integrated space/water heating systems, as well as an evaluation of alternative sidewall venting technologies and their implications for seasonal energy ...

1996-07-01

174

Statistical cut-off criterion

Current scientific knowledge of climate change and its global impact is summarized in the first four chapters. The earth's natural climate, greenhouse gases, climate prediction models, and impact of a warmer world on natural terrestrial ecosystems, agricultural ecosystems, and coastal regions are discussed. The possible impacts on Canada are described in chapter five, which considers forests, agriculture, water resources, fisheries, coastal zones, transportation, human health and well being, energy production and use, and global security. Chapter six considers ways to respond to climate change. These include enhancing knowledge of climate change, working toward a consensus on the need for action, global political response, the Canadian response, and the role of the individual. 15 refs., 35 figs.

2005-10-15

175

Parameter Regionalization of Semi-Distributed Runoff Model Using Multivariate Statistical Analysis

... radiation effects human populations low dose irradiation neoplasms radiation

1980-01-01

176

Minimization on Stochastic Matroids

Full Text Available

2009-02-01

177

HIGH ORDER STATISTICAL SIGNATURES FROM SOURCE-DRIVEN MEASUREMENTS OF SUBCRITICAL FISSILE SYSTEMS

... Note that the terminal ... Probability and Statistics with Reliability, Queueing, and Computer ... Weiss, G., "Stochastic Bounds on Distributions of Optimal ...

1990-07-01

178

No abstract prepared.

1998-04-01

179

Environmental Economics

Multicolor FISH mapping with Alu-PCR-amplified YAC clone DNA determines the order of markers in the BRCA1 region on chromosome 17q12-q21

environmental burden is studied by testing the Environmental Kuznets Curve hypothesis as well as application of statistical decomposition

180

Identification and characterization of populations living near high-voltage transmission lines: A pilot study

A gene designated BRCA1, implicated in the susceptibility to early-onset familial breast cancer, has recently been localized to chromosome 17q12-q21. To date, the order of DNA markers mapped within this region has been based on genetic linkage analysis. The authors report the use of multicolor fluorescence in situ hybridization to establish a physically based map of five polymorphic DNA markers and 10 cloned genes spanning this region. Three cosmid clones and Alu-PCR-Generated products derived from 12 yeast artificial chromosome clones representing each of these markers were used in two-color mapping experiments to determine an initial proximity of markers relative to each other on metaphase chromosomes. Interphase mapping was then employed to determine the order and orientation of closely spaced loci by direct visualization of fluorescent signals following hybridization of three probes, each detected in a different color. Statistical analysis ...

1993-09-01

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181

Comparison of the radiobiological effect of carbon ion beam therapy and conventional radiation therapy on cervical cancer

Populations living close to high-voltage transmission lines often have residential magnetic field exposures in excess of 1 [mu]T, and sometimes over 2 [mu]T. Yet, populations studied in most epidemiologic investigations of the association between residential magnetic field exposure and cancer typically have exposures below 1 [mu]T and frequently below 0.5 [mu]T. To improve statistical power and precision, it would be useful to compare high exposure populations with low exposure population. Toward this end, we have developed an automated method for identifying populations living near high-voltage transmissions lines. These populations likely have more highly exposed individuals that the population at large. The method uses a geographic information system (GIS) to superimpose digitized transmission line locations on U.S. Census block location data and then extract relevant demographic data. Analysis of data from a pilot study of the population ...

1993-12-01

182

Vocational rehabilitation services for patients with cancer: design of a feasibility study incorporating a pilot randomised controlled trial among women with breast cancer following surgery

Little clinical evidence has been provided to show the minimization of radiation resistance of tumors using high linear energy transfer radiation. We therefore investigated the radiobiological and molecular pathological aspects of carbon beam therapy. A total of 27 patients with squamous cell carcinoma (SCC) of the cervix were treated using a carbon beam and 50 control patients with SCC of the cervix using a photon beam. The expression of Ki-67, p53, and p27 proteins before radiotherapy and 5 and 15 days after therapy initiation were investigated using immunohistochemistry. Similar changes were observed in Ki-67 labeling index (LI) and p53 LI during carbon and photon beam therapies. However, for carbon beam therapy, the mean p27 LI significantly decreased from 25.2% before treatment to 18.6% on the 5th day after treatment initiation, followed by a significant increase to 36.1% on the 15th day. In contrast, for photon beam therapy, the p27 LI consistently decreased from the initial ...

2008-09-01

183

Usefulness of High-B-value Diffusion - Weighted MR Imaging for the Pre-operative Detection of Rectal Cancers

BackgroundDue to improvements in cancer survival the number of people of working age living with cancer across Europe is likely to increase. UK governments have made commitments...Full Text Available

184

Road to Recovery from Prostate Cancer

Full Text Available

2009-12-01

185

... have the support of the hospital, from the CEO to administration, to the chief of urology that ...

186

Ovarian Cancer

Occult brain metastases in HER2-positive breast cancer patients: Frequency and response to radiotherapy

... opening the abdomen surgically. This surgery may be laparoscopic, using special scopes. It could also be an ...

187

Intrathecal Catheter and Subcutaneous Access Port Implantation in Pain Management for Terminal Cancer Patient - A case report -

No abstract prepared.

2007-10-15

188

Hypodiploidy, Ki-67 growth fraction and prognosis of surgically resected lung cancers.

Full Text Available

2007-12-01

189

High grade prostatic intraepithelial neoplasia in military workingn> dogs with and without prostate cancer.

One hundred and thirty-seven lung cancer patients (123 non-small-cell lung cancers (NSCLC), 10 small-cell lung cancers (SCLC) and four carcinoid tumours) who underwent surgery in an attempt at complete...Full Text Available

1996-09-01

190

G2 checkpoint siRNA screen in irradiated cancer cells: validation of candidate positive hits

PMID:9687991

1998-08-01

191

Norwegian Open Research Archives (NORA)

Full Text Available

192

DNA adducts and cancer risk in prospective studies: a pooled analysis and a meta-analysis

DEFF Research Database (Denmark)

Udgivelsesdato: 2008-May

2008-01-01

193

Clinical Usefulness of Implanted Fiducial Markers for Hypofractionated Radiotherapy of Prostate Cancer

Clinical Experience of 3T Breast MRI in Detecting the Additional Lesions in Breast Cancer Patients

Full Text Available

2011-06-01

194

Capsaicin induced apoptosis and the enhanced anticancer effect of anticancer drugs in cancer cells

Full Text Available

2010-12-01

195

Assesment of guardian node in breast cancer

Full Text Available

2008-03-01

196

Antiproliferation Effects of Germinated-Korean Rough Rice Extract on Human Cancer Cells

2004 p. 32 Poland Jastrzebski, T. Klinika Chirurgii Onkologicznej, Akademia

197

Human papillomavirus: science and technologies for the elimination of cervical cancer

Full Text Available

2010-03-01

198

British Library Electronic Table of Contents (United Kingdom)

Introduction: Academic research has made a significant advancement in understanding the viral causes of cervical cancer and generating the technology for prevention, both at the primary and secondary levels. Human papillomaviruses (HPVs) have been recognized as the first necessary cause of cervical cancer, the second most common cancer in women worldwide. Areas covered: This paper reviews the epidemiological evidence of the causality of HPV in relation to cervical cancer, other genital tract cancers and some cancers of the oral cavity and oropharynx. The review also covers HPV DNA testing as a screening tool. DNA probes of high-risk HPV types in different formats have been fully validated as primary screening tests, as secondary triage tests and as a prognostic marker following treatment o...

2011-01-01

199

BUBL LINK: Skin cancer

Senate vote to kill Climate Act disrespects Canadians and democracy | Notes from the Panther Lounge | David Suzuki Foundation

...CanCom Dermatology Image Bank Dermatology Online Atlas Introduction to Skin Cancer Malignant Melanoma Skin Cancer (Not Melanoma) Comments: bubl@bubl.ac.... Covers anatomy, melanoma, infections, and dermatological disorders in AIDS. Author: University of Utah ...994 Resource type: document Malignant Melanoma This leaflet on malignant melanoma covers early detection, causes, clinical signs and symptoms, and provides ...9 Resource type: document Skin Cancer (Not Melanoma) Information on basal cell and squamous cell skin cancers. Author: ...

200

Novel Staphylococcal Cassette Chromosome mec Type, Tentatively Designated Type VIII, Harboring Class A mec and Type 4 ccr Gene Complexes in a Canadian Epidemic Strain of Methicillin-Resistant Staphylococcus aureus?

... This is an amount less that the measurement accuracy of even the best meteorological instruments . So, is it really worth committing to 40 years of drastic carbon emissions reductions (which necessarily involves increasing the cost of hydrocarbon fuels in order to reduce fuel consumption, and force an industry-wide conversion to much more expensive alternative energy sources), all so that after nearly all of us are ...

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201

Getting to grips with remote handling and robotics

Staphylococcal cassette chromosome mec (SCCmec) is a mobile genetic element characterized by flanking terminal direct and, in most cases, inverted repeat sequences,...Full Text Available

2009-02-01

202

Entering the Canadian mainstream. [The independent energy market in Canada

A report on the Canadian Nuclear Society Conference on robotics and remote handling in the nuclear industry, September 1984. Remote handling in reactor operations, particularly in the Candu reactors is discussed, and the costs and benefits of use of remote handling equipment are considered. Steam generator inspection and repair is an area in which practical application of robotic technology has made a major advance. (U.K.).

203

Coal deposits in the front ranges and foothills of the Canadian Rocky Mountains, southern Canadian Cordillera

This article examines the developing market for independent power projects in Canada. The topics of the article include bidding in Ontario, the Quebec market, powering British Columbia, and market forces at work in Canada. Discussed are current projects in all stages of completion from bidding to production and includes gas-fired cogeneration, gas-fired combined-cycle electricity generation and cogeneration, wood-waste fired plants, repowering of existing utility plants, and hydroelectric power plants.

1992-04-01

204

Canadian natural gas winter 2006-07 outlook

Over one-third of Canada's coal resources occurs in the southern Canadian Rocky Mountains, with major deposits in the Front Ranges, Inner Foothills and Outer Foothills. In the Front Ranges, deposits of metallurgical and thermal, high-volatile bituminous to semi-anthracite coal occur in the Late Jurassic-Early Cretaceous Mist Mountain Formation. In the Inner Foothills of northeastern British Columbia and west-central Alberta, resources of metallurgical and thermal medium- and low-volatile bituminous coal occur in Early Cretaceous strata of the Gething and Gates Formations. In the Outer Foothills resources of thermal, high-volatile bituminous coal occur in Late Cretaceous and Paleocene strata of the Belly River Coalspur and Paskapoo Formations. The major deposits of the Front Ranges and Inner Foothills accumulated within the coastal plains of the Fernie and Moosebar-Clearwater seas. Shorelines prograded to the north and northeast into a foreland basin that ...

1993-09-01

205

Achieving cholesterol targets by individualizing starting doses of statin according to baseline low-density lipoprotein cholesterol and coronary artery disease risk category: The CANadians Achieve Cholesterol Targets Fast with Atorvastatin Stratified Titration (CanACTFAST) study

This paper provided an outline of the Canadian natural gas commodity market and a forecast for Canadian natural gas supply and prices for the 2007 winter heating season. Since 2001, steady demand growth and slow supply growth have contributed to higher North American natural gas commodity prices. The loss of natural gas supply due to hurricanes pushed North American natural gas commodity prices to record levels in 2005. Canadian natural gas production levels currently exceed domestic gas consumption. In 2005, Canada produced 16.5 billion cubic feet per day of marketable natural gas. Approximately 45 per cent was consumed domestically, and the remainder was exported to the United States. Despite high levels of drilling activity, production of natural gas from western Canada has flattened out since 2001. In 2006, natural gas prices in Canada declined due to the restoration of United States Gulf Coast natural gas production; ...

206

44th Canadian geotechnical conference: Preprint volume. 44th conference canadienne de geotechnique

BACKGROUND:Despite an increasing body of evidence on the benefit of lowering elevated levels of low-density lipoprotein cholesterol (LDL-C), there is still considerable concern that...Full Text Available

2010-02-01

207

Identification of prostate cancer antigens by automated high-throughput filter immunoscreening

A conference on geotechnics presented papers on soil properties, soil liquefaction, slope stability, pile foundations, numerical modelling, engineering geology, rock mechanics, cold regions engineering, oil sands, irrigation, environmental engineering, geosynthetics, and geotechnical case histories. Separate abstracts have been prepared for 29 papers from the conference.

1991-01-01

208

British Library Electronic Table of Contents (United Kingdom)

There is a need for earlier and more accurate cancer diagnostics as well as new targets for cancer immunotherapy. To this end, it is important to identify sets of tumour antigens specific for different cancer forms. Several methods that identify potential tumour antigens in an arrayed and high-throughput format have been developed during the last years of SEREX (serological identification of antigens by recombinant expression cloning) related research. Such techniques may hold the potential to describe the complete immunogenic part of the cancer proteome, also called the cancer immunoproteome.We have developed a powerful platform for automated serological high-throughput filter screening of tumour cDNA libraries. The screening format of this method is 18,000 single cDNAs clones, which is s...

2008-01-01

209

Green Tea Extract (Epigallocatechin-3-Gallate) Reduces Efficacy of Radiotherapy on Prostate Cancer Cells

British Library Electronic Table of Contents (United Kingdom)

ObjectivesTo assess the influence of epigallocatechin-3-gallate (EGCG) on the efficacy of ionizing radiation on prostate cancer cells because of the increased use of dietary interventions, especially by patients with prostate cancer. Radiotherapy is used to treat localized prostate cancer. Some people consume green tea (EGCG) as a chemopreventive agent against prostate cancer. Green tea can act as an antioxidant and induce superoxide dismutase enzymes, which could scavenge the free oxygen radicals generated by radiotherapy. MethodsProstate cancer cell line DU145 cells were treated with EGCG or radiotherapy, or both. Cell death was assessed using trypan blue cell counting, and apoptosis was confirmed by assessing poly (adenosine phosphate ribose) polymerase cleavage. The antioxidant potenti...

2011-01-01

210

Epidemiological studies concerned with exposure to extremely low frequency electromagnetic fields and the risk of cancer

Consumption of filtered and boiled coffee and the risk of incident cancer: a prospective cohort study

Extensive epidemiological studies have been carried out in recent years to examine the possible effects of exposure to extremely low frequency electromagnetic fields on the development of cancer. In some studies, both residential and occupational, a number of cancers, in particular leukaemia and brain cancer, have occurred at an increased incidence at higher levels of exposure. In general, however, no consistent and coherent pattern of results has been obtained and no clear evidence of a cancer risk has been demonstrated. A better understanding of any effect of electromagnetic fields on the development of cancer must await the results of more informative epidemiological studies and an improved understanding of the mechanisms by which these fields may interact with the body and their likely consequences. (author)

1997-12-01

211

British Library Electronic Table of Contents (United Kingdom)

Background Despite potentially relevant chemical differences between filtered and boiled coffee, this study is the first to investigate consumption in relation to the risk of incident cancer. Methods Subjects were from the V?sterbotten Intervention Project (64,603 participants, including 3,034 cases), with up to 15?years of follow-up. Hazard ratios (HR) were calculated by multivariate Cox regression. Results No associations were found for all cancer sites combined, or for prostate or colorectal cancer. For breast cancer, boiled coffee ?4 versus <1 occasions/day was associated with a reduced risk (HR?=?0.52, CI?=?0.30?0.88, p trend?=?0.247). An increased risk of premenopausal and a reduced risk of postmenopausal breast cancer were found for both total (HRpremenopausal?=?1.69, CI?=?0.96?2.98...

2010-01-01

212

High-dose radiation therapy for inoperable non-small cell lung cancer without mediastinal involvement (clinical stage N0, N1)

Statistical treatment of the inner M-shell excitation in heavy ion-atom collisions

To evaluate the usefulness of radiation therapy alternative to surgery for clinical N0-N1 non-small cell lung cancer (NSCLC). From 1976 through 1989, 116 patients with NSCLC without mediastinal involvement were treated with definitive radiation therapy alone at Gunma University Hospital. All patients were treated with once-daily standard fractionation using 10 MV X-rays. The total dose ranged from 60 Gy to 80 Gy. The actuarial 2- and 5-year survival rates of the entire group were 43% and 20%, respectively with a median survival time of 19 months. The survival of 76 patients with stage T2 tumors was significantly better than that of 28 patients with T3 tumors (mean survival time 21 versus 15.5 months; p<0.05). Sixty-two patients with tumors less than 5 cm in diameter had a 2-year progression rate of 20%, in comparison with 39% of 54 patients with tumors greater than 5 cm. The difference of survivals for these 2 groups was statistically ...

1996-09-01

213

Statistical Support Document for Proposed Effluent Limitations Guidelines and Standards for the Metal Products and Machinery Industry.

A statistical treatment has been applied to interpret the experimental data on the Xe M-shell vacancy production in slow 1.05 MeV Xe-Xe collisions and is shown to give better agreement with experiment than that of the molecular-orbital models.

1983-06-27

214

SEGMENTING CT PROSTATE IMAGES USING POPULATION AND PATIENT-SPECIFIC STATISTICS FOR RADIOTHERAPY

Table of Contents: Overview of Organization and Contents of Document; Analytical Data Collection Efforts and Definition of Options; Description of Data Conventions; Statistical Methodology: Modified Delta-Lognormal Model; Estimation Under the Modified Del...

2000-01-01

215

OECD Pakistan Aid Statistics

This paper presents a new deformable model using both population and patient-specific statistics to segment the prostate from CT images. There are two novelties in the proposed method. First,...Full Text Available

2009-08-07

216

Profile of aid statistics to Pakistan. Shows the amount of aid received, the major donors and the form in which the majority of the aid is given. Especially useful when compared to the aid profile of similar countries. Shows that ODA accounts for about 1.5% of Pakistani GDP and that it is distributed over various sectors.

217

NAME=\\

A statistical framework for modeling gene expression using chromatin features and application to modENCODE datasets

...Programme Manager Interests Multilevel Statistical Modelling Geography of Health and Health Care Geographical Data Analysis Census Data Analysis Health Services Research (in particular Research Design, Statistical Analysis and Epidemiology) people/mgould.html Homepage | Contacts | Site Map | Privacy Statement | Webmaster | ...

218

THE APPLICATION OF STATISTICS TO THE FLIGHT ...

We develop a statistical framework to study the relationship between chromatin features and gene expression. This can be used to predict gene expression of protein coding genes, as well as microRNAs....Full Text Available

2011-01-01

219

Statistical Indicators Report.

... Measuring Instruments ..... 7-18 7.4 Power Spectral Density Measurements of Random DaL. .... 7-19 7 ...

1961-12-01

220

SAMS Research and Development

... Sick leave usage amounts to 72.4 hours per employee. ... Quits are resignations and individual tran;fers to other Federal Agencies. ...

2011-05-14

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221

A quantum-statistical-mechanical extension of Gaussian mixture model

... resolution video. RESULTS Statistics describing the typical inertial navigation error growth were collected. Typical errors ...

2008-08-06

222

X-Ray Phase Imaging for Breast Cancer Detection

We propose an extension of Gaussian mixture models in the statistical-mechanical point of view. The conventional Gaussian mixture models are formulated to divide all points in given data to some kinds of classes. We introduce some quantum states constructed by superposing conventional classes in linear combinations. Our extension can provide a new algorithm in classifications of data by means of linear response formulas in the statistical mechanics.

2008-01-15

223

Whole-genome cancer analysis as an approach to deeper understanding of tumour biology

... Accession Number : ADA535309. Title : X-Ray Phase Imaging for Breast Cancer Detection. Descriptive Note : Annual rept. 1 Sep 2009-31 Aug 2010 ...

2010-09-01

224

Whipple Procedure for Pancreatic Cancer

Recent advances in DNA sequencing technology are providing unprecedented opportunities for comprehensive analysis of cancer genomes, exomes, transcriptomes, as well as epigenomic components. The integration...Full Text Available

2010-01-19

225

Voiding and Sexual Function after Autonomic-Nerve-Preserving Surgery for Rectal Cancer in Disease-Free Male Patients

... be able to watch the many intricate steps Dr. Richard Alexander must accomplish to remove the cancer. ... door to informed medical care. Now let's join Dr. Richard Alexander at the University of Maryland Medical ...

226

Variants in Inflammation Genes and the Risk of Biliary Tract Cancers and Stones: A Population-based Study in China

PurposeWe evaluated the effects of surgery for rectal cancer on postoperative voiding and sexual function over the course of time.Materials and MethodsData...Full Text Available

2010-12-01

227

Urinary symptoms and impact on quality of life in women after treatment for endometrial cancer

To evaluate the role of chronic inflammation in the development of gallstones and biliary tract cancer, we examined the risk associated with 62 single nucleotide polymorphisms (SNPs), including...Full Text Available

2008-08-01

228

Tumor-derived extracellular mutations of PTPRT/PTP? are deficient in cell adhesion

The primary objective of our study is to describe urinary symptoms in women treated for endometrial cancer. We performed a cross-sectional survey of women who had undergone surgical treatment...Full Text Available

2009-02-01

229

Tumor-Endothelial Interaction Links the CD44⁺/CD24^- Phenotype with Poor Prognosis in Early-Stage Breast Cancer1

Receptor protein tyrosine phosphatase T (PTPRT/PTPρ) is frequently mutated in human cancers including colon, lung, gastric and skin cancers. More than half of the identified tumor-derived...Full Text Available

2008-07-01

230

Transposons for cancer gene discovery: Sleeping Beauty and beyond

Materials and MethodsThe genomic effects of tumor-endothelial interactions in cancer are not yet well characterized. To study this interaction in breast...Full Text Available

2009-10-01

231

Transposon-based screens for cancer gene discovery in mouse models

The use of Sleeping Beauty transposons as somatic mutagens to discover cancer genes in hematopoietic tumors and sarcomas has been documented. Here, we discuss the future of Sleeping...Full Text Available

2007-01-01

232

Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo

Significant emphasis has recently been placed on the characterization of the human cancer genome. This effort has been assisted by the development of new DNA sequencing technologies that allow...Full Text Available

2010-08-01

233

Therapy of Primary Breast Cancer

BackgroundThymoquinone (TQ) is a compound extracted from Black Caraway seeds of Nigella Sativa and is active against various cancers. Cisplatin (CDDP) is the most...Full Text Available

234

The workplace: Monitoring and prevention of occupational hazards. Volume 4

Most breast cancers are multicentric in origin. They drain into two primary lymphatic depots—the axilla and internal mammary chain of nodes. The incidence of metastasis to the internal mammary...Full Text Available

1970-04-01

235

The Perceived Care Needs of Breast Cancer Patients in Korea

This book examines the occupational health hazards imposed by neoplasms. Topics considered include: cancer as an occupational hazard; an overview; epidemiological evidence; and interaction of host and lifestyle factors with occupational chemicals in cancer causation.

1985-01-01

236

The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes

By analyzing the data of 459 patients who completed the Supportive Care Needs Survey (SCNS), the prevalence, medical and non-medical predictors of unmet needs were investigated. Breast cancer patients...Full Text Available

2006-08-31

237

Targeting Prostate Cancer Cells In Vivo Using a Rapidly Internalizing Novel Human Single-Chain Antibody Fragment

Objective. Cervical cancer patients who had an abandoned radical hysterectomy were evaluated for preoperative clinical predictors, complication rates, and outcomes. Study...Full Text Available

2010-01-01

238

TJ-41 Induces Apoptosis and Potentiates the Apoptotic Effects of 5-FU in Breast Cancer Cell Lines

Human antibodies targeting prostate cancer cell surface epitopes may be useful for imaging and therapy. The objective of this study was to evaluate the tumor targeting of an internalizing human...Full Text Available

2010-03-01

239

T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells

Recent studies suggest that TJ-41, a herbal drug, possesses chemotherapeutic effects. Accordingly, this study was undertaken to investigate the anticarcinogenic effects of TJ-41 on human breast cancer...Full Text Available

2009-01-01

240

Surveillance for the detection of early lung cancer in patients with bronchial dysplasia

Epidermal growth factor receptor (EGFR)-specific monoclonal antibodies predominantly inhibit colorectal cancer (CRC) growth by interfering with receptor signaling. Recent analyses have shown that patients...Full Text Available

2010-07-13

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241

Sphincter preservation for distal rectal cancer - a goal worth achieving at all costs?

BackgroundThe natural history of bronchial preinvasive lesions and the risk of developing lung cancer in patients with these lesions are not clear. Previous studies have treated...Full Text Available

2007-01-01

242

Smoking cessation and lung cancer risk in an Asian population: Findings from the Singapore Chinese Health Study

To assess the merits of currently available treatment options in the management of patients with low rectal cancer, a review of the medical literature pertaining to the operative and non-operative management...Full Text Available

2011-02-21

243

Skin Cancer in Skin of Color

Background:Smoking cessation is an important strategy for reducing the harmful effects of tobacco, particularly in the prevention of lung cancer; however, prospective data on the...Full Text Available

2010-09-28

244

SirT1 brings stemness closer to cancer and aging

Skin cancers in skin of color often present atypically or with advanced stage in comparison to Caucasian patients. Health care providers must maintain a high index of suspicion when examining...Full Text Available

2009-01-01

245

Serum HER2 Level Measured by Dot Blot: A Valid and Inexpensive Assay for Monitoring Breast Cancer Progression

Sirtuin 1 acts in various cell processes, deacetylating both chromatin and non-histone proteins, and its role in cancer and aging has long been studied and debated. Here we discuss another aspect of...Full Text Available

246

Sequential Molecular and Cellular Events during Neoplastic Progression: A Mouse Syngeneic Ovarian Cancer Model1

Human epidermal growth factor receptor 2 (HER2) is one of the most important prognostic and predictive factors for breast cancer patients. Recently, serum HER2...Full Text Available

247

Second primary cancers of the breast: incidence and risk factors.

AbstractStudies performed to identify early events of ovarian cancer and to establish molecular markers to support early detection and development of chemopreventive regimens have been...Full Text Available

2005-10-01

248

Romantic and Sexual Relationships, Body Image, and Fertility in Adolescent and Young Adult Testicular Cancer Survivors: A Review of the Literature

Between 1946 and 1976 over 9,000 women with breast cancer were seen within one year of diagnosis at the A. Maxwell Evans Clinic (AMEC) in Vancouver, British Columbia. By 1978, 275 had a subsequent diagnosis...Full Text Available

1984-01-01

249

Role of Estrogen Receptor-? in the Regulation of Claudin-6 Expression in Breast Cancer Cells

This review presents a summary of existing knowledge regarding the impact of testicular cancer along four broad domains, including romantic and sexual relationships, body image, and fertility....Full Text Available

2010-08-01

250

Risk of cancer after low doses of ionising radiation: retrospective cohort study in 15 countries

PurposeIn our previous studies we showed that upregulating claudin-6 (CLDN6) expression may contribute to preventing breast cancer, and that 17β-estradiol induces a concentration-...Full Text Available

2011-03-01

251

Reproductive factors and risks of biliary tract cancers and stones: a population-based study in Shanghai, China

Objectives To provide direct estimates of risk of cancer after protracted low doses of ionising radiation and to strengthen the scientific basis of radiation protection standards for environmental,...Full Text Available

2005-07-09

252

Relevance of circulating nucleosomes and oncological biomarkers for predicting response to transarterial chemoembolization therapy in liver cancer patients

Background:Parity has been linked to gallbladder cancer and gallstones, but the effects of other reproductive factors are less clear.Methods:We examined...Full Text Available

2010-03-30

253

Rapid detection of epidermal growth factor receptor mutations with multiplex PCR and primer extension in lung cancer

BackgroundTransarterial chemoembolization (TACE) therapy is an effective locoregional treatment in hepatocellular cancer (HCC) patients. For early modification of therapy, markers...Full Text Available

254

Radical Resection After IORT-Containing Multimodality Treatment is the Most Important Determinant for Outcome in Patients Treated for Locally Recurrent Rectal Cancer

Epidermal growth factor receptor (EGFR) kinase domain mutations hyperactivate the kinase and confer kinase addiction of the non-small-cell lung cancer (NSCLC) tumor...Full Text Available

255

Quality of life in patients with head and neck cancers.

BackgroundThe optimal treatment for locally recurrent rectal cancer (LRRC) is still a matter of debate. This study assessed the outcome of LRRC patients treated with multimodality...Full Text Available

2008-07-01

256

Quality of life in patients with esophageal stenting for the palliation of malignant dysphagia

OBJECTIVE: The aim was to assess the psychosocial effects on the quality of life (QOL) of adults with head and neck cancer (HNC) and any gender variations with predictive factors that may influence...Full Text Available

2006-05-01

257

Putative Biomarkers and Targets of Estrogen Receptor Negative Human Breast Cancer

Incidence of esophageal cancer (EC) is rising more rapidly in the Western world than that of any other cancer. Despite advances in therapy, more than 50% of patients have incurable disease at the time...Full Text Available

2011-01-14

258

Protocadherin-PC Promotes Androgen-Independent Prostate Cancer Cell Growth

Breast cancer is a progressive and potentially fatal disease that affects women of all ages. Like all progressive diseases, early and reliable diagnosis is the key for successful treatment and annihilation....Full Text Available

259

Proteomic patterns analysis with multivariate calculations as a promising tool for prompt differentiation of early stage lung tissue with cancer and unchanged tissue material

BACKGROUNDProtocadherin-PC (PCDH-PC) expression is upregulated in apoptosis-resistant sublines of the LNCaP human prostate cancer (CaP) cell line. Here, we assess...Full Text Available

2006-07-01

260

Proteome of human colon cancer stem cells: A comparative analysis

BackgroundLung cancer diagnosis in tissue material with commonly used histological techniques is sometimes inconvenient and in a number of cases leads to ambiguous conclusions. Frequently...Full Text Available

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261

Protein expression based multimarker analysis of breast cancer samples

AIM: To isolate and identify the biological characteristics of human colon cancer stem cells (SW1116 cells) and further study their proteome.METHODS: SW1116 cells were isolated and cultured with...Full Text Available

2011-03-14

262

Prognostic Significance of Peritumoral Lymphatic Vessel Density and Vascular Endothelial Growth Factor Receptor 3 in Invasive Squamous Cell Cervical Cancer

BackgroundTissue microarray (TMA) data are commonly used to validate the prognostic accuracy of tumor markers. For example, breast cancer TMA data have led to the identification...Full Text Available

263

Prediction and diagnosis of bladder cancer recurrence based on urinary content of hTERT, SENP1, PPP1CA, and MCM5 transcripts

Cervical cancer is known to metastasize primarily by the lymphatic system. Dissemination through lymphatic vessels represents an early step in regional tumor progression, and the presence of lymphatic...Full Text Available

264

Phytoestrogens: epidemiology and a possible role in cancer protection.

BackgroundIdentification of urinary biomarkers for detection of bladder cancer recurrence would be beneficial to minimize the frequency of cystoscopy. Our objective was to determine...Full Text Available

265

Phosphatidic acid signaling to mTOR: Signals for the survival of human cancer cells

Because many diseases of the Western Hemisphere are hormone-dependent cancers, we have postulated that the Western diet, compared to a vegetarian or semivegetarian diet, may alter hormone production,...Full Text Available

1995-10-01

266

Pancreatic cancer: molecular pathogenesis and new therapeutic targets

During the past decade elevated phospholipase D (PLD) activity has been reported in virtually all cancers where it has been examined. PLD catalyzes the hydrolysis of phosphatidylcholine to generate...Full Text Available

2009-09-01

267

PLESIOTHERAPY FOR NON-MELANOMA SKIN CANCER: INNOVATING TO OVERCOME!

Patients with pancreatic cancer normally present with advanced disease that is lethal and notoriously difficult to treat. Survival has not improved dramatically, despite routine use of chemotherapy...Full Text Available

2009-07-01

268

Ovarian cancer mouse models: a summary of current models and their limitations

Background:The non-surgical management of non-melanoma skin cancers is an area requiring clinical investigation. Radiotherapy has a role in treatment for a defined subset...Full Text Available

2010-10-01

269

Oligomycin-induced Bioenergetic Adaptation in Cancer Cells with Heterogeneous Bioenergetic Organization

Development of mouse models representing human spontaneous ovarian cancer has been hampered by the lack of understanding of the etiology of this very complex disease. Mouse models representing the different...Full Text Available

270

Nucleoside Drugs Induce Cellular Differentiation by Caspase-Dependent Degradation of Stem Cell Factors

Cancer cells constantly adapt to oxidative phosphorylation (OXPHOS) suppression resulting from hypoxia or mitochondria defects. Under the OXPHOS suppression, AMP-activated protein kinase (AMPK) regulates...Full Text Available

2010-04-23

271

Nuclear ? catenin as a potential prognostic and diagnostic marker in patients with colorectal cancer from Hong Kong

BackgroundStem cell characteristics are an important feature of human cancer cells and play a major role in the therapy resistance of tumours. Strategies to target cancer stem cells...Full Text Available

272

Nonbacterial thrombotic endocarditis associated with cancer of unknown origin complicated with thrombus in the left auricular appendage: case report

Aims: To study the expression of nuclear β catenin in patients with colorectal cancer, colorectal adenoma, and colorectal polyps to elucidate its role in carcinogenesis, and its...Full Text Available

2003-12-01

273

Neoadjuvant vs adjuvant pelvic radiotherapy for locally advanced rectal cancer: Which is superior?

A 63-year-old man was admitted to our hospital with a complaint of right lateroabdominal pain. He was diagnosed with metastatic colon cancer, and then developed multiple brain embolic infarctions 7...Full Text Available

274

Nanochemoprevention: Sustained Release of Bioactive Food Components for Cancer Prevention

The treatment of locally advanced rectal cancer including timing and dosage of radiotherapy, degree of sphincter preservation with neoadjuvant radiotherapy, and short and long term effects of radiotherapy...Full Text Available

2011-02-21

275

Morbidity using subcutaneous ports and efficacy of vancomycin flushing in cancer.

Chemoprevention, especially through the use of naturally occurring phytochemicals capable of impeding the process of carcinogenesis at one or more steps, is an ideal approach for cancer management....Full Text Available

2010-10-01

276

Mechanisms of confluence-dependent expression of CD26 in colon cancer cell lines

An evaluation of totally implanted venous access systems inserted in 163 consecutive children with cancer is reported. From 1988 to 1994, 180 subcutaneous ports were inserted in children more than 1...Full Text Available

1995-04-01

277

Massachusetts' approach to the prevention of heart disease, cancer, and stroke.

BackgroundCD26 (dipeptidyl peptidase IV, DPPIV) is a 110 kDa surface glycoprotein expressed in most normal tissues, and is a potential novel therapeutic target for selected cancers....Full Text Available

278

Mass spectrometry-based analysis of therapy-related changes in serum proteome patterns of patients with early-stage breast cancer

Heart disease, cancer, and cerebrovascular disease together cause more than two out of three deaths in the United States annually. These three diseases are largely a result of widespread risk factors...Full Text Available

1986-01-01

279

Luminal and basal-like breast cancer cells show increased migration induced by hypoxia, mediated by an autocrine mechanism

BackgroundThe proteomics approach termed proteome pattern analysis has been shown previously to have potential in the detection and classification of breast cancer. Here we aimed...Full Text Available

280

Long-term disease-free survival after surgical resection for multiple bone metastases from rectal cancer

BackgroundSome breast cancer patients receiving anti-angiogenic treatment show increased metastases, possibly as a result of induced hypoxia. The effect of hypoxia on tumor cell...Full Text Available

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281

Life-Span Exposure to Low Doses of Aspartame Beginning during Prenatal Life Increases Cancer Effects in Rats

Bone metastasis of primary colorectal cancer is uncommon. When it occurs, it is usually a late manifestation of disease and is indicative of poor prognosis. We describe a patient with multiple metachronous...Full Text Available

2011-08-10

282

Life after Breast Cancer: Dealing with Lymphoedema

BackgroundIn a previous study conducted at the Cesare Maltoni Cancer Research Center of the European Ramazzini Foundation (CMCRC/ERF), we demonstrated for the first time that aspartame...Full Text Available

2007-09-01

283

Lessons to be Learned from 25 Years of Research Investigating Psychosocial Interventions for Cancer Patients

Background:In recent years, breast cancer (BC) mortality rates have declined, reflecting advances in early detection. Prevention and management of treatment sequelae that could impair...Full Text Available

284

Lack of Osteoradionecrosis of the Mandible after IMRT for Head and Neck Cancer: Likely Contributions of both Dental Care and Improved Dose Distributions

Conducting rigorous psychosocial intervention research with cancer patients has many challenges including encouraging them to join studies, asking them to engage in interventions or be part...Full Text Available

2009-01-01

285

Initial Report of the Cancer PROMIS Supplement Sexual Function Committee: Review of Sexual Function Measures and Domains Used in Oncology

PurposeTo assess the prevalence and the dosimetric and clinical predictors of mandibular osteoradionecrosis (ORN) in patients with head and neck (HN) cancer who underwent...Full Text Available

2007-06-01

286

Incidence of cancer among Finnish airline cabin attendants, 1967-92.

ObjectiveThis report describes initial activities of the Cancer Patient-Reported Outcomes Measurement Information System (PROMIS) Sexual Function domain group (CaPS-SF),...Full Text Available

2009-03-15

287

Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice

OBJECTIVE--To assess whether occupational exposure among commercial airline cabin attendants are associated with risk of cancer. DESIGN--Record linkage study. SETTING--Finland. SUBJECTS-1577 female...Full Text Available

1995-09-09

288

Improvement of a Dendritic Cell-Based Therapeutic Cancer Vaccine with Components of Toxoplasma gondii?

Hyperproliferation of the colonic epithelium, leading to expansion of colonic crypt progenitors, is a recognized risk factor for colorectal cancer. Overexpression of progastrin, a nonamidated and incompletely...Full Text Available

2009-09-01

289

Impact of intraoperative lung-protective interventions in patients undergoing lung cancer surgery

The use of dendritic cells (DCs) as a cellular adjuvant is a promising approach to the immunotherapy of cancer. It has previously been demonstrated that DCs pulsed ex vivo with Toxoplasma gondii...Full Text Available

2009-10-01

290

If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice

IntroductionIn lung cancer surgery, large tidal volume and elevated inspiratory pressure are known risk factors of acute lung (ALI). Mechanical ventilation with low tidal volume...Full Text Available

2009-01-01

291

Identification and Functional Relevance of de novo DNA Methylation in Cancerous B-Cell Populations

Hyperglycemia and hyperinsulinemia accelerate both aging and cancer. Antidiabetic biguanides such as metformin decrease glucose, insulin and IGF-1 level. Metformin increases lifespan and prevents cancer...Full Text Available

292

Hormone Receptor Status in Breast Cancer and its Relation to Age and Other Prognostic Factors

Epigenetic remodeling is a hallmark of cancer, with the frequent acquisition of de novo DNA methylation in CpG islands. However, the functional relevance of de novo...Full Text Available

2010-03-01

293

Background:Increasing evidence shows the importance of young age, estrogen receptor (ER), progesterone receptor (PR) status, and HER-2 expression in patients with breast cancers.Patients...Full Text Available

294

Haplotype of N-Acetyltransferase 1 and 2 and Risk of Pancreatic Cancer

PurposeIntestinal stomas can pose significant challenges for long-term (≥ 5 years) rectal cancer (RC) survivors. Specifying common challenges and sociodemographic or clinical...Full Text Available

2009-10-01

295

Green tea polyphenols for prostate cancer chemoprevention: A translational perspective

We examined the association between N-acetyltransferase 1 and 2 (NAT1 and NAT2) haplotype and risk of pancreatic cancer by genotyping eight...Full Text Available

2007-11-01

296

Genetically-engineered mouse models for pancreatic cancer: Advances and current limitations

Every year nearly 200,000 men in the United States are diagnosed with prostate cancer (PCa), and another 29,000 men succumb to the disease. Within certain regions of the world population based...Full Text Available

2010-01-01

297

Genetic association between the COMT genotype and urinary levels of tea polyphenols and their metabolites among daily green tea drinkers

Recently, there has been significant progress in the development of genetically-engineered mouse (GEM) models. By introducing genetic alterations and/or signaling alterations of human pancreatic cancer...Full Text Available

2011-05-10

298

Functional Enhancers at the Gene-Poor 8q24 Cancer-Linked Locus

Available in vitro and animal studies have shown cancer protective effects of tea polyphenols. Recent study suggests a greater protective effect of green tea intake on breast cancer...Full Text Available

299

Follow-up of patients with curatively resected colorectal cancer: a practice guideline

Multiple discrete regions at 8q24 were recently shown to contain alleles that predispose to many cancers including prostate, breast, and colon. These regions are far from any annotated gene and their...Full Text Available

2009-08-01

300

First line targeted therapies in breast cancer: focus on bevacizumab

BackgroundA systematic review was conducted to evaluate the literature regarding the impact of follow-up on colorectal cancer patient survival and, in a second phase, recommendations...Full Text Available

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301

Figuring Out Sex in a Reconfigured Body: Experiences of Female Colorectal Cancer Survivors with Ostomies

The heterogeneity of metastatic breast cancer mandates the need to select therapies taking into account tumor and patient characteristics. Chemotherapy is indicated in the palliative setting especially...Full Text Available

2007-03-01

302

Fatigue and Functional Impairment in Early-Stage Non-Small Cell Lung Cancer Survivors

Colorectal cancer (CRC) survivors with ostomies can face complex concerns regarding sexuality. We used an anthropological perspective to examine the experiences of 30 female CRC survivors with...Full Text Available

2009-12-01

303

Expression Signatures of Metastatic Capacity in a Genetic Mouse Model of Lung Adenocarcinoma

ContextFatigue is the most common sequela among non-small cell lung cancer (NSCLC) survivors 1–6 years post-treatment and is associated with functional limitations.Full Text Available

2011-02-01

304

Evaluation of support groups for women with breast cancer: importance of the navigator role

BackgroundNon-small cell lung cancer (NSCLC) is the foremost cause of cancer-related death in Western countries, which is due partly to the propensity of NSCLC cells to metastasize....Full Text Available

305

Estimation of cancer incidence and mortality attributable to alcohol drinking in china

BackgroundAt least some forms of breast cancer are increasingly being viewed as a chronic illness, where an emphasis is placed on meeting the various ongoing needs of people living...Full Text Available

306

Epigenetic Therapies for Chemoresensitization of Epithelial Ovarian Cancer

BackgroundCancer constitutes a serious burden of disease worldwide and has become the second leading cause of death in China. Alcohol consumption is causally associated with the...Full Text Available

307

Epidemiological appraisal of studies of residential exposure to power frequency magnetic fields and adult cancers.

SummaryEpigenetic drugs have been shown to enhance gene expression and drug sensitivity in ovarian cancer cell lines and animal models. Based on promising pre-clinical studies,...Full Text Available

2010-02-01

308

Enhancing return-to-work in cancer patients, development of an intervention and design of a randomised controlled trial

OBJECTIVES: To appraise epidemiological evidence of the purported association between residential exposure to power frequency magnetic fields and adult cancers. METHODS: Literature review and epidemiological...Full Text Available

1996-08-01

309

Endobronchial Stent Insertion to Manage Hemoptysis caused by Lung Cancer

BackgroundCompared to healthy controls, cancer patients have a higher risk of unemployment, which has negative social and economic impacts on the patients and on society at large....Full Text Available

310

Diverging trends in incidence and mortality of testicular cancer in Denmark, 1943-1982.

Hemoptysis in patients with lung cancer is not uncommon and sometimes have dangerous consequences. Hemoptysis has been managed with various treatment options other than surgery and medicine, such as...Full Text Available

2010-08-01

311

Differing prognosis of cervical cancer patients with high risk of treatment failure after radical hysterectomy warrants trial treatment modification

Between 1943 and 1982, 5,140 new cases of testicular cancer were diagnosed in Denmark. The age-standardized incidence rate more than doubled in the period. Striking variations is seen in the age-relationship...Full Text Available

1986-04-01

312

Diesel engine exhaust and lung cancer: an unproven association.

ObjectiveThe aim of this study was to ascertain whether all cervical cancer patients who received adjuvant concurrent chemoradiation (CCRT) for high risk of treatment failure after...Full Text Available

2009-03-01

313

Development and validation of a high performance liquid chromatography method for the simultaneous determination of aspirin and folic acid from nano-particulate systems

The risk of lung cancer associated with diesel exhaust has been calculated from 14 case-control or cohort studies. We evaluated the findings from these studies to determine whether there is sufficient...Full Text Available

1995-09-01

314

Cytotoxicity of Atriplex confertifolia

Attention has shifted from the treatment of colorectal cancer (CRC) to chemoprevention using aspirin and folic acid as agents capable of preventing the onset of colon cancer. However, no sensitive...Full Text Available

2010-09-01

315

Current status of therapy for breast cancer worldwide and in Japan

The search for cancer treatment continues to be a global effort. As part of this global effort, many natural products have been tested against cancer cell lines, mostly from tropically located plants....Full Text Available

2010-01-01

316

Current practices in the spatial analysis of cancer: flies in the ointment

The results of clinical trials conducted in Europe and North America have been incorporated into treatment strategies for breast cancer in Japan. Despite the use of similar treatment regimens, why has...Full Text Available

2011-02-10

317

Comprehensive Management of Upper Tract Urothelial Carcinoma

While many lessons have been learned from the spatial analysis of cancer, there are several caveats that apply to many, if not all such analyses. As "flies in the ointment", these can substantially...Full Text Available

318

Common mitochondrial polymorphisms as risk factor for endometrial cancer

Urothelial carcinoma of the upper urinary tract represents only 5% of all urothelial cancers. The 5-year cancer-specific survival in the United States is roughly 75% with grade and stage being the most...Full Text Available

2009-01-01

319

Common Familial Colorectal Cancer Linked to Chromosome 7q31: a genome-wide analysis

Endometrial carcinoma is the most commonly diagnosed gynaecological cancer in developed countries. Although the molecular genetics of this disease has been in the focus of many research laboratories...Full Text Available

320

Colonic polyps: inheritance, susceptibility, risk evaluation, and diagnostic management

Present investigations suggest that approximately 30% of colorectal cancer (CRC) cases arise on the basis of inherited factors. We hypothesize that the majority of inherited factors are moderately...Full Text Available

2008-11-01

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321

Clinical Implications of Immunohistochemically Demonstrated Lymph Node Micrometastasis in Resectable Pancreatic Cancer

Colorectal cancer (CRC) is the third-ranked neoplasm in order of incidence and mortality, worldwide, and the second cause of cancer death in industrialized countries. One of the most important environmental...Full Text Available

322

Childhood cancer mortality and radon concentration in drinking water in North Carolina.

The purpose of this study was to determine the clinical significance of nodal micrometastasis detected by immunohistochemistry in patients that had undergone curative surgery for pancreatic cancer....Full Text Available

2011-07-01

323

Childhood cancer and overhead powerlines: a case-control study.

We explored the association between groundwater radon levels and childhood cancer mortality in North Carolina. Using data from two state-wide surveys of public drinking water supplies, counties were...Full Text Available

1991-04-01

324

Chemoprevention of Nonmelanoma Skin Cancer With Celecoxib: A Randomized, Double-Blind, Placebo-Controlled Trial

A case-control study has been carried out to examine the occurrence of childhood cancer in relation to the proximity of overhead power lines to a child's home address at birth and to the calculated...Full Text Available

1990-12-01

325

Catalyzing Social Support for Breast Cancer Patients

BackgroundPreclinical studies indicate that the enzyme cyclooxygenase 2 plays an important role in ultraviolet-induced skin cancers. We evaluated the efficacy and safety of celecoxib,...Full Text Available

2010-12-15

326

Carcinoma in situ of contralateral testis in patients with testicular germ cell cancer: study of 27 cases in 500 patients.

Social support is a critical, yet underutilized resource when undergoing cancer care. Underutilization occurs in two conditions: (a) when patients fail to seek out information, material assistance,...Full Text Available

2010-01-01

327

Cancer in young people in the north of England, 1968-85: analysis by census wards.

Carcinoma in situ in the contralateral testis was diagnosed in 27 of 500 patients (5.4%) with unilateral testicular germ cell cancer. Eight of the 27 patients received intensive chemotherapy for spread...Full Text Available

1986-11-29

328

CDC - Annual Report to the Nation on the Status of Cancer, 1975...

OBJECTIVE--To determine whether the seeming excess of childhood leukaemia and lymphoma identified in Seascale, Cumbria, UK, remains unusual when put into a wider context. DESIGN--Analysis of cancer...Full Text Available

1993-04-01

329

Breast cancer and human papillomavirus infection: No evidence of HPV etiology of breast cancer in Indian women

tumors make up two-thirds of all adult brain tumors and one-third of childhood brain tumors. Cancer Among Men, 2003-2007 Incidence rates decreased for lung, colorectal,...

2011-10-15

330

Blood leukocyte DNA hypomethylation and gastric cancer risk in a high-risk Polish population

BackgroundTwo clinically relevant high-risk HPV (HR-HPV) types 16 and 18 are etiologically associated with the development of cervical carcinoma and are also reported to be present...Full Text Available

331

Blood Storage Duration and Biochemical Recurrence of Cancer After Radical Prostatectomy

Global hypomethylation has been shown to increase genome instability potentially leading to increased cancer risk. We determined whether global methylation in blood leukocyte DNA was associated...Full Text Available

2010-10-15

332

Autofluorescence bronchoscopy for lung cancer surveillance based on risk assessment

OBJECTIVE: To test the hypothesis that perioperative transfusion of allogeneic and autologous red blood cells (RBCs) stored for a prolonged period speeds biochemical recurrence of prostate cancer...Full Text Available

2011-02-01

333

Association between intratumoral lymphatic microvessel density (LMVD) and clinicopathologic features in endometrial cancer: a retrospective cohort study

BackgroundThis is a preliminary report of an ongoing prospective bimodality lung cancer surveillance trial for high‐risk patients. Bimodality surveillance incorporates autofluorescence...Full Text Available

2007-04-01

334

Assessment of nodal target definition and dosimetry using three different techniques: implications for re-defining the optimal pelvic field in endometrial cancer

BackgroundLymph node metastasis in endometrial cancer significantly decreases survival rate. Few data on the influence of intratumoral lymphatic microvessel density (LMVD) on survival...Full Text Available

335

An Analysis of Heavy Utilizers of Opioids for Chronic Non-Cancer Pain in the TROUP Study

Purposes1. To determine the optimal pelvic nodal clinical target volume for post-operative treatment of endometrial cancer. 2. To compare the DVH of different treatment planning...Full Text Available

336

Alcohol-folate interactions in women's oral cancer risk: A prospective cohort study

ContextWhile opioids are increasingly used for chronic non-cancer pain (CNCP), we know little about opioid dosing patterns among individuals with CNCP in usual care...Full Text Available

2010-08-01

337

Acute aortic thrombosis in patients receiving cisplatin-based chemotherapy

BackgroundThe aim of this cohort study was to quantify the effect of alcohol in the risk of oral cancer in different strata of folate intake, controlling for known...Full Text Available

2010-10-01

338

Activation of Cytotoxic and Regulatory Functions of NK Cells by Sindbis Viral Vectors

The increased risk of thrombosis in patients with active cancer has multiple causes. Acute thrombosis of the aorta is an exceedingly rare but potentially devastating complication in patients with cancer...Full Text Available

2011-04-01

339

A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer

Oncolytic viruses (OVs) represent a relatively novel anti-cancer modality. Like other new cancer treatments, effective OV therapy will likely require combination with conventional treatments. In order...Full Text Available

340

A decision-analytic approach to define poor prognosis patients: a case study for non-seminomatous germ cell cancer patients

IntroductionVarious multigene predictors of breast cancer clinical outcome have been commercialized, but proved to be prognostic only for hormone receptor (HR) subsets overexpressing...Full Text Available

2010-01-01

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341

A church-based intervention to promote informed decision-making for prostate cancer screening among African-American men

BackgroundClassification systems may be useful to direct more aggressive treatment to cancer patients with a relatively poor prognosis. The definition of 'poor prognosis' often lacks...Full Text Available

342

A Multi-Method Process Evaluation for a Skin Cancer Prevention Diffusion Trial

ObjectivesThis feasibility study developed and pilot tested an intervention to: (1) increase knowledge about prostate cancer (CaP) screening; and (2) promote self-efficacy...Full Text Available

2010-03-01

343

This article describes process evaluation methods for the Pool Cool Diffusion Trial across four years. Pool Cool is a skin cancer prevention program that was...Full Text Available

2009-06-01

344

?H2AX and cancer

Vitamin C increases the apoptosis via up-regulation p53 during cisplatin treatment in human colon cancer cells

Histone H2AX phosphorylation on a serine four residues from the carboxyl terminus (producing γH2AX) is a sensitive marker for DNA double-strand breaks (DSBs). DSBs may lead to cancer...Full Text Available

2008-12-01

345

Triptolide-induced suppression of phospholipase D expression inhibits proliferation of MDA-MB-231 breast cancer cells.

Full Text Available

2011-03-01

346

The reirradiation of the cavum cancer. Experience of the oncology center Ibn-Rochd of Casablanca (C.O.I.R.); La reirradiation du cancer du cavum. Experience du centre d'oncologie Ibn-Rochd de Casablanca (COIR)

Full Text Available

2009-09-01

347

New mass screening project for lung cancer with mobile spiral computed tomography (CT) and computed radiography (CR) in Ehime district

The radiotherapy is the prime treatment for the cavum cancer. It is also useful to treat the tumor recurrences, in this case the reirradiation stays the only efficient therapy option to give a correct local control. The reirradiation, exclusive or in association with other therapies can contribute to the local control of cavum cancer recurrences with a survival rate at five years of 36 to 58%. (N.C.)

2006-11-15

348

Detection of Mitochondrial DNA Mutations in Mammary ...

To improve the detection rate of lung cancer, we have introduced low-dose CT and CR technique into a population-based annual mass screening. From December 1999, 3868 and 12618 individuals participated in this screening program with CT and with CR, respectively. Primary lung cancer was detected in 15 (0.39%) by CT and 8 (0.06%) by CR. This results show high detection rate of primary lung cancer as had been previously reported. (author)

2002-01-01

349

Synergistic epigenetic reactivation of estrogen receptor-? (ER?) by combined green tea polyphenol and histone deacetylase inhibitor in ER?-negative breast cancer cells

... Loss of Heterozygosity in Normal Breast Epithelial Tissue and Benign Breast Lesions in BRCA1/2 Carriers with Breast Cancer. ...

2004-09-01

350

Proton beam therapy for cancer in deep-seated organs

BackgroundThe status of estrogen receptor-α (ERα) is critical to the clinical prognosis and therapeutic approach in breast cancer. ERα-negative breast cancer...Full Text Available

351

Mammography: limits of a technique

Radiation therapy has shown definite technical improvement due to application of proton beam irradiation. Clinical results of proton beam therapy also suggested enlargement of indication ranges in radial treatment and decrease of post radiation damages of the treatment of cancers in deep-seated organs. Inprovement of result in cancer therapy could be expected by this treatment technique in the future.

1988-10-01

352

Long-term chemical carcinogenesis experiments for identifying potential human cancer hazards: collective database of the National Cancer Institute and National Toxicology Program (1976-1991).

Breast cancer represents today more than 30% of all cancers and is responsible for about 20% of deaths due to cancer. The potentialities of mammography have increased in recent years through improvements in equipment and methodologies. In this paper the conventional mammography using film and image intensifiers is compared with digital mammography. Digital mammography presents clear advantages in storage and handling of information. Also its higher sensitivity will lead to an earlier detection of anomalies and a decrease in the number of invasive exams and surgeries

2001-05-01

353

LY294002 may overcome 5-FU resistance via down-regulation of activated p-AKT in Epstein-Barr virus-positive gastric cancer cells

The carcinogenicity database used for this paper originated in the late 1960s by the National Cancer Institute (NCI) and since 1978 has been continued and made more comprehensive by the National Toxicology...Full Text Available

1991-12-01

354

Indian Academy of Sciences - Summer Fellowships 2005

BackgroundAs EBV-associated gastric cancer has unique features that are different from EBV (-) gastric cancer, EBV is considered to have a key role in gastric carcinogenesis. It...Full Text Available

355

Indian Academy of Sciences (India)

kodali, mr (iii b.tech.) anil neerukonda inst. of science and chandrashekaran ramachandra reddy shekhar c mande lang="en-gb">kandavelmani, reg. cancer cen., trivandrum panda panda lang="en-gb">dr anand imtech, chandigarh lang="en-gb">ravichandran, reg. cancer cen., trivandrum reg. cancer cen., trivandrum chandrasekar, dr (lecturer) psg college of arts & science, imtech, chandigarh ...

356

Update on well-baby and well-child care from 0 to 5 years

Light duty mobile, portable and stationary power for military applications

AbstractOBJECTIVETo provide an overview of the 2009 edition of the Rourke Baby Record (RBR), which incorporates recent research in the literature relating to preventive health care for children aged 0 to 5 years.QUALITY OF EVIDENCERecommendations are identified as supported by good, fair, or consensus evidence, according to the classification of the Canadian Task Force on Preventive Health Care.MAIN MESSAGENew information and recommendations are given for growth monitoring, nutrition, developmental surveillance, physical examination maneuvers, immunization schedules, and advice for parents. Anticipatory guidance updates relate to injury prevention, infant swaddling, literacy facilitation, nonparental child care, parenting skills programs, serum lead levels, over-the-counter cough and cold medications, pacifiers, antipyretics, insect repellents, and dental care and oral health. The 2009 RBR is available in English and French in both National and Ontario versions and ...

2010-12-01

357

Challenges in environmental monitoring and reporting

Hydrogenics is a leading global developer of hydrogen and fuel cell products for onsite generation and power and test systems. Hydrogenics has been working with the Canadian military since 1996, and also has contracts for portable hydrogen systems with the National American Space Agency (NASA), and the United States Army. This presentation highlighted a number of Hydrogenics' fuel cell technologies for military and commercial applications. Products included portable military generators, electrolysers and reformers, backup power systems, and regenerative satellite systems. Specifications, warranties and power capabilities for the batteries and systems were presented. Details of the company's testing facilities and procedures were provided, as well as a case study of a fuel cell hybrid vehicle. Details of the HyPORT-E 5 kW Regenerative Fuel Cell Auxiliary Power Unit were presented, as well as a feasibility study for the use of fuel cells in ...

2006-07-01

358

Canadian upstream oil and gas industry fire and explosion incident analysis based on the investigative work of the IRP18 Committee working with the University of Calgary Department of Chemical and Petroleum Engineering. Revision 1

The Canadian Association of Petroleum Producers (CAPP) represents about 170 crude oil and natural gas exploration, development and production companies in regulatory hearings and legal proceedings. Its principal role is to enhance the economic well-being and sustainability of the Canadian upstream petroleum industry. This presentation explores the role that information technology (IT) plays in knowledge and information management and how this role relates to meeting Canada`s target for greenhouse gas emissions reductions set by the Kyoto Protocol. Actions such as the Voluntary Challenge Registry (VCR) and emissions reductions trading are re-visited and the information requirements associated with these actions are highlighted. It is shown that among others, emissions databases between jurisdictions (provincial, national, international) have to be integrated, reduction claims must be tracked, verified and cross-referenced to eliminate double ...

1998-12-31

359

Augmenting the Core Battery with Supplementary Subtests: Wechsler Adult Intelligence Scale-IV Measurement Invariance across the United States and Canada

This report presented an analysis of incidents gathered by the Canadian upstream oil and gas industry committee in relation to explosive atmospheres in wellbores, vessels, tanks, and piping systems. The aim of the report was to develop industry recommended practices for oil and gas industry fires and explosions. Two accident theory models were used to set out the relationships between hazards, defenses, and losses. Three levels of defenses were identified based on organizational, local workplace, and human factors. An organizational responsibility approach was used to examine the activities of key people with the system. Incidents were analyzed based on an expanded fire triangle used to identify fire and explosion hazards. The study showed that the ignition of hydrocarbons into the air was a factor in nearly 50 per cent of the incidents. A lack of understanding of liquid-hydrocarbon properties was demonstrated in incidents involving oxidized hydrocarbons. A lack of ...

2005-05-15

360

Examination of measurement invariance provides a powerful method to evaluate the hypothesis that the same set of psychological constructs underlies a set of test scores in different populations. If measurement invariance is observed, then the same psychological meaning can be ascribed to scores in both populations. In this study, the measurement model including core and supplementary subtests of the Wechsler Adult Intelligence Scale-Fourth edition (WAIS-IV) were compared across the U.S. and Canadian standardization samples. Populations were compared on the 15 subtest version of the test in people aged 70 and younger and on the 12 subtest version in people aged 70 or older. Results indicated that a slightly modified version of the four-factor model reported in the WAIS-IV technical manual provided the best fit in both populations and in both age groups. The null hypothesis of measurement invariance across populations was not rejected, and the results provide direct ...

2011-06-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

361

The RooStats Project

Year 2000 preparedness: a presentation to the House of Commons Standing Committee on Industry

RooStats is a project to create advanced statistical tools required for the analysis of LHC data, with emphasis on discoveries, confidence intervals, and combined measurements. The idea is to provide the major statistical techniques as a set of C++ classes with coherent interfaces, which can be used on arbitrary model and datasets in a common way. The classes are built on top of RooFit, which provides a very convenient functionality for modeling the probability density functions or the likelihood functions, required as inputs for any statistical technique. Furthermore, RooFit provides the functionality for easily creating models, for analysis combination and for digital publication of the likelihood function and the data. We will present in detail the design and the implementation of the different statistical methods of RooStats. These include various classes for interval estimation and for hypothesis ...

2010-01-01

362

Tritium bioassay and dosimetry at a CANDU reactors

An overview of the Canadian mining industry`s state of preparedness for the Year 2000 is presented. Committees within the mining industry are working on scheduling and implementing activities, defining criticality, monitoring remedial action, and contingency planning. The Mining Association of Canada is working with the Federal Government`s National Contingency Planning Group to deal with potential threats to health and security. Survey results suggest that mining poses a low to medium risk based on the state of planning for Y2K. The results of a survey of member preparedness is tabulated. 1 tab.

1999-05-13

363

The calculation of derived release limit on Wolsung NPPs based on reduced public dose limit

Tritium dose management is an important aspect of the radiation protection program at CANDU type reactor sites. This paper describes the bioassay and dosimetry of tritium at CANDU reactor sites, especially for Wolsung Nuclear Power Plant. It presents a compilation of information drawn from published papers, technical reports, international and national guidelines as well as practical experience both in Korean and Canadian CANDU Nuclear Power Plants. The implementation of this program would provide a technical basis for calculations and records should be of acceptable quality and should meet overall radiation protection program objectives.

1996-07-01

364

Proceedings of the fourth international airborne remote sensing conference and exhibition/ 21st Canadian symposium on remote sensing

According to enactment of reduced dose limit based on ICRP-60, the calculation of Derived Release Limits(DRL) on Wolsung NPPs was carried out. There are two methods of determination on DRL; that is MPC(Maximum Permissible Concentration) method and system analysis method. In order to use the system analysis method, lots of environmental data are necessary and complicated exposure pathway are considered. So we intend to apply MPC method that is sort of simple. In addition the calculated results were compared with derived release limit on Canadian nuclear power plant.

2000-10-01

365

Proceedings of the Canadian Society for Bioengineering CSBE/SCGAB 2009 annual general meeting and technical conference

The theme of the conference was recent developments in airborne remote sensing and their applications. The proceedings contain the papers presented at 14 general sessions and 13 interactive sessions covering airborne platforms, sensor systems, airborne/spaceborne synergy, atmospheric and oceanic measurements, land cover/land use, emergency response and reconnaissance, data handling, forestry, agriculture, water resources, geospatial reference, system calibration, environmental monitoring and planning, and information product advancements. Two papers are abstracted separately.

1999-07-01

366

Proceedings of the Canadian Society for Bioengineering CSBE/SCGAB 2008 annual meeting

This conference was attended by experts on current issues in engineering of an urban ecosystem, composting, biofuels and green energy. The meeting provided a forum to discuss advances in the application of engineering principles and practices dealing with biological systems for the production of food, bioproducts and energy. The discussions focused on engineering practices in agriculture, forestry, bioresources, biochemistry and biosystems. The 7 technical sessions of the conference were entitled: aquaculture; safety and training; bioprocessing; energy production and biofuels; environment and ecology; soil and water; and development of technologies. The conference feature 58 presentations, of which 9 have been catalogued separately for inclusion in this database. refs., tabs., figs.

2009-07-01

367

Proceedings of CanWEA's 2006 conference and trade show

This conference provided a forum to discuss advances in the application of bioengineering principles and practices dealing with biological systems for the production of food, bioproducts and energy. The topics of discussion ranged from engineering practices in agriculture, forestry, bioresources, biochemistry and biosystems. The sessions of the conference were entitled: renewable energy; waste management; soil and water; machinery systems; building and storage systems; and bioproducts and food. The conference also featured a workshop on integrated biomass supply and logistics. In addition to 20 posters, the conference featured 67 presentations, of which 3 have been catalogued separately for inclusion in this database. refs., tabs., figs.

2008-07-01

368

The Canadian wind energy industry is experiencing rapid and unprecedented growth. The year 2006 saw the installation of 534 MW of wind energy across Canada, representing approximately $1 billion in new investment. It is anticipated that the wind energy industry will help to create jobs and training opportunities for many Canadians, as well as provide ongoing economic benefits to local communities through municipal tax and land lease payments. However, many challenges remain if Canada is to meet, or exceed, its objective of a total of 10,000 MW in installed wind energy by 2015. This conference provided a forum for wind industry member, academics and representatives of both governmental and non-governmental agencies to discuss issues related to wind energy development. The conference was divided into 3 streams. The policy stream examined issues related to the Canadian Wind Power Production Incentive (WPPI) program, as well as ...

2006-10-22

369

Canadian nuclear review

A study for good regulation of the CANDU's in Korea

Progress in the construction of Candu reactors at home and abroad is surveyed. Some A.E.C.L. research projects are also mentioned. During 1979, Candu reactors again showed their superior capacity factors, four of them being among the ten most reliable reactors in the world. Progress in construction at Pickering B, Bruce B, Point Lepreau, Gentilly-2, Darlington, Wolsung (Korea), Cordoba (Argentina), and Cernavoda (Romania) is recounted. In 1979, it was unfortunately necessary to replace installed steam generators at Pickering B, Bruce B, Point Lepreau and Gentilly-2. At Wolsung, the reactor was pre-assembled before installation, which is a new technique. (N.D.H.).

1979-01-01

370

Validation of the Canadian atmospheric dispersion model for small exclusion area boundaries

The objective of project is to derive the policy recommendations to improve the efficiency of CANDU plants regulation. These policy recommendations will eventually contribute to the upgrading of Korean nuclear regulatory system and safety enhancement. During the second phase of this 2 years study, following research activities were done. Review the technical basis and framework of the new Canadian Regulation System and IAEA. Analysis on the interview of Wolsung operation staffs to identify important safety issues and regulation problems experienced at operation. Providing a plan of CANDU regulation system enhancement program.

2002-03-15

371

Reply to comments on the proposed on-road vehicle and engine emission regulations

AECL is undertaking the validation of ADDAM, an atmospheric dispersion and dose code based on the Canadian Standards Association model CSA N288.2. The key component of the validation program involves the comparison of air concentrations predicted by the model with measured values. Measurements are available from field studies at two Canadian reactor sites and from a wind tunnel study of the CANDU site at Wol song, Korea. The measurements were obtained close enough to the release points to test the model for exclusion area boundaries as small as 500 m. Model predictions were higher than the observations almost 75 percent of the time and the magnitude of the over predictions was typically much larger than the magnitude of the under predictions. The effect of the topography at the Wol song site was limited to small changes in plume trajectory due to channeling in valleys and a small reduction in the lateral spread of the plume. The terrain did not ...

1999-11-04

372

Ground-level ozone: Our new environmental policy

In February 2001, the Minister of Environment Canada outlined a series of measures to be implemented over the next decades to reduce emissions from vehicles, engines and fuels. The agenda includes the development of new regulations under the authority of Part 7, Division 5 of the Canadian Environmental Protection Act (CEPA) to align Canada's emission standards for on-road vehicles with those of the United States Environmental Protection Agency. This paper presents a detailed summary of comments received by the interested parties that appeared at a public consultation in November 2001 to discuss and raise issues about the proposed regulations. The parties that provided submissions included: governments; the vehicle and engine manufacturing industry; the oil industry; other groups of associations such as the Canadian Trucking Alliance, David Suzuki Foundation, and West Coast Environmental Law; and, five private individuals. The report ...

2002-12-01

373

Engineering masterpieces : from the Andes to Siberia, Canadian talent is in demand

The environmental problem of ground level ozone is discussed, and the Canadian strategy for dealing with it is explained. Ozone in the troposphere can cause serious health problems in susceptible persons, and is estimated to cause up to $70 million in crop damage per year. The Canadian Council of Ministers of the Environment (CCME) Plan calls for less than 82 ppB by volume of ozone in any one-hour period in all areas of Canada by 2005. Three areas of Canada regularly exceed this value: the Lower Frazer valley in British Columbia, Saint John in New Brunswick, and the Windsor-Quebec corridor along the lower Great Lakes and the St. Lawrence River. Ozone is formed by a photochemical reaction of ammonia gases, nitrogen oxides, hydrogen sulfide or sulfur dioxide. Historically, ozone control has concentrated on controlling hydrocarbon emissions, but to little effect. In most locations close to large cities, ozone production is nitrogen oxide-limited, ...

374

After inventory and assessment : what was found out and what was done about it

Canadian oilfields are a prime breeding ground for talent, technology and industrial management. This paper described how Canadian talent was recognized in 2001 for three major projects which included a cold-ocean production platform in the Sea of Okhotsk in Siberia, a mountain pipeline project in South America, and an in-situ underground extraction technology in the oilsands of Alberta. The cold-ocean production platform project was recruited by Sakhalin Energy Investment Co., an international consortium originally led by Marathon Oil Co which is now led by Royal Dutch Shell. The oil production platform is stationed 16 kilometres offshore of Sakhalin Island in the Sea of Okhotsk. Sakhalin Energy bought and converted the Molikpaq, an innovative platform made in the 1980s for the Beaufort Sea by Gulf Canada Resources Ltd. The second project included Calgary's Hydroconsult EN3 Services Ltd. which was responsible for the construction of ...

2001-03-05

375

Selective changes of retroelement expression in human prostate cancer

Some of the methodologies, techniques, dependencies and lessons learned regarding the year 2000 (Y2K) project currently underway at PanCanadian are described. The Y2K problem, which is a date related malfunction associated with the turn of the century, may affect computers and automated control systems. The cost of fixing this world wide problem ranges from $52 billion to $2 trillion. At PanCanadian, central to ensuring that the entire corporation is ready for the Year 2000 is a dedicated project team in the information technology (IT) department who manage all the life-cycle software for the company. IT staff purchase, install and remove all obsolete software and data. Inventory, testing and remediation of all software, hardware and embedded systems are the basis of the plan of action adopted by the I.T. Y2K project team. Dealing with Y2K problems of business partners, and planning for business interruption are special problems for which ...

376

British Library Electronic Table of Contents (United Kingdom)

Retroelements constitute a large part of the human genome. These sequences are mostly silenced in normal cells, but genome-wide DNA hypomethylation in cancers might lead to their re-expression. Whether this re-expression really occurs in human cancers is largely unkown. We therefore investigated expression and DNA methylation of several classes of retroelements in human prostate cancer tissues and cell lines by quantitative reverse transcription-polymerase chain reaction and pyrosequencing, respectively. The most striking finding was strong and generalized increased expression of the HERV-K_22q11.23 provirus in cancers, including de novo expression of a spliced accessory Np9 transcript in some tumors. In parallel, DNA methylation in the long terminal repeat (LTR) decreased. Conversely, HER...

2011-01-01

377

Quality of life after surgery for rectal cancer with special reference to pelvic floor dysfunction

British Library Electronic Table of Contents (United Kingdom)

Abstract Aim- Conventional outcomes such as survival, tumour recurrence and complication rates after surgery for rectal cancer have been rigorously assessed, but the importance of maintaining quality of life (QOL) after surgery for rectal cancer has received less attention. The aim of the current study was to analyse QOL and the occurrence of pelvic dysfunction after the surgical treatment of rectal cancer. Method- Between May 2005 and May 2008, 150 patients with rectal cancer underwent abdominoperineal resection (APR) or anterior resection (AR). Seventy-four answered two preoperative questionnaires. At a follow up of 1-year, 65 were alive without sign of recurrence and answered the same questionnaires: (a) validated RAND 36-item health survey QOL questionnaire; and (b) self-administered d...

2011-01-01

378

Pain measurement: the affective dimensional measure of the McGill pain questionnaire with a cancer pain population.

Isoflavone content and apoptotic effect in HT-29 cancer cells of a soy germ extract

Two experiments used the McGill Pain Questionnaire (MPQ) to examine the affective dimension of pain in patients whose pain was secondary to malignancy. In experiment I, segregating groups of cancer patients on the basis of extreme scores (high versus low) on the MPQ failed to produce segregation on independent measures of affect and infirmity. This outcome contrasts with earlier work with chronic benign pain patients. Experiment II compared cancer pain patients matched with benign pain patients on intensity of pain report on the affective dimension of the MPQ. Cancer pain patients reported a reliably higher affective loading to their pain. These data suggest that cancer pain patients employ different criteria than benign pain patients in selecting affective pain descriptors. Possible explanations for this difference are discussed. PMID:7070825

1982-02-01

379

British Library Electronic Table of Contents (United Kingdom)

Colon cancer is one of the leading causes of death and a major public health problem in western countries. We examined the isoflavone content of 70% ethanol extract of soy germ (SG) and its apoptotic effect in HT-29 colon cancer cells. Our results showed that the major isoflavones of the SG extract were daidzein and genistein, and it effectively induced apoptosis in HT-29 cancer cells. In addition, nuclear factor-kappa B (NF-kB) expression was reduced in cells treated with the SG extract, which reduced cyclooxygenase-2 (COX-2) and nitric oxide synthase (iNOS) expression. These combined effects ultimately resulted in apoptosis via caspase-3 activation. In addition, daidzein and genistein, the major isoflavones of SG extract, also exerted the apoptotic effect against HT-29 cancer cells. Thes...

2012-01-01

380

Application of microvascular free osteocutaneous flaps in the management of post-radiation recurrent oral cancer

Some thoughts on stem cells and carcinogenesis. The thyroid gland

Fifty-nine patients underwent free flap osteocutaneous reconstruction that consisted of flaps of the dorsum of the foot in 26 patients and iliac crest flaps in 33 with a success rate of 92 percent and a mortality rate of 1.6 percent. These flaps, which require the expertise of microvascular surgeons, are time-consuming and complicate operating room and time management, but they represent a remarkable advance in reconstruction that can facilitate cosmetic and functional recovery of the patient. In particular, they promote healing in radiation-recurrent oral cancer and represent a definitive form of management for established radionecrosis of the mandible. The large volume of tissue available with iliac crest osteocutaneous grafts permits the management of patients with extensive cancer involving the skin, mucosa, and bone, but cancer control may still be disappointing and there is a need for improved adjuvant chemotherapy ...

1985-10-01

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381

Efficacy of MR mammography (MRM) in providing preoperative locoregional information on breast cancer. Correlation between MRM and histological findings

The purpose of this review is to consider the hypothesis that cancer frequently originates from stem cells. Using the spleen transplantation assay where stem cells were transplanted in the spleen of mice lethally irradiated by ionizing radiation, the author undertook a study aimed at defining the risk of radiogenic cancer per susceptible cells with use of rat radiogenic mammary and thyroid cancers because of the high incidences of these cancers in a-bomb survivors. Measured were the number of cancer-susceptible cells initially present in the tissue, the number of such cells that survived at a given dose and the number of cancers that developed per surviving cell. Thyroid cell differentiation and proliferation in rats transplanted with thyroid cells were enhanced by thyroidectomy and low iodine diet. Further, the relationship between the low LET radiation dose ...

2000-07-01

382

Childhood cancer in the surroundings of German nuclear power plants: report of an ongoing epidemiological study; Krebs bei Kindern in der Umgebung von Kernkraftwerken: Bericht zu einer laufenden epidemiologischen Studie

The purpose of this study was to assess the efficacy of MRM in providing preoperative locoregional information on patients with breast cancer. MRI was performed on 62 female breast cancer patients. A 1.5 T MR-system was used to acquire fat-suppressed T{sub 1}WI, T{sub 2}WI and dynamic-contrast-enhanced images with an SPGR pulse sequence. The extent of the cancer measured with MRM was confirmed histologically in all patients. The size obtained from MRM correlated well with the size obtained histologically, including intraductal spread of cancer (R: 0.853). As for shape, the round/oval type evident from MRM correlated more accurately (R: 0.934) than the ill-defined type associated with a linear and/or clumped enhanced area (R:0.744). The difference between the size obtained from MRM and the size obtained histologically, including IDS, was less than 15 mm in the majority of patients (93.5%). MRM accurately ...

2002-07-01

383

In-vitro radioimmunoassay of prostate specific antigen (PSA) for the screening and management of prostate cancer in Lebanon

Epidemiological studies could not show an association between ionising radiation of nuclear power stations in routine operation and the incidence of childhood cancer, yet. The following report presents a case control study conducted by the German Childhood Cancer Registry since autumn 2003. All children in the study region, who were diagnosed with cancer between 1980 and 2003 at an age below five are included. In the first part of the study we investigate whether children with cancer (cases) lived closer to the respective nuclear power stations compared to random children without cancer (controls). In the second part, for a subgroup of cases and controls we conduct computer assisted telephone interviews regarding confounders possibly associated with the exposure of ionising radiation and childhood cancer. Results are expected by the end of 2006. (orig.)

2006-07-01

384

Full text: Immunoassays for prostate-specific antigen (PSA) are used to detect early-stage prostate cancer, monitor disease progress, and evaluate therapeutic response. At least two forms of PSA, free PSA (F-PSA) and PSA complexed to alpha-1 anti-chymotrypsin (PSA-ACT) are detected by commercial PSA assays. The fraction of F-PSA is shown to be smaller in patients with untreated prostate cancer than in patients with benign prostate hyperplasia (BPH). Thus, combined measurements of both total and free PSA are used for a better discrimination between BPH and prostate cancer. Detection of PSA for screening of prostate cancer has been a subject of debate for many years. The reason of this debate is mainly because screening for prostate cancer is not cost-effective, as was shown by studies undertaken in Europe and United States. In Lebanon, no previous programs of screening for prostate ...

2004-01-01

385

unido.org

Theory of the crystal-liquid phase transition

...Events Archive Worldwide Africa Programme Arab Programme Asia and Pacific Programme Europe and NIS Programme Latin American and Caribbean Programme Least-Developed Countries South-South Cooperation Human Security Directory of Offices Research & Statistics Publications Research and Statistics Subsites Annual Report Evaluation Group Investment and Technology Promotion Policymaking Organs Legal Resources Goodwill Ambassadors Industrial Competitiveness and Trade Private Sector Development Environmental Management Energy and Climate Change Research and Statistics Financial Institutions Partnerships Thematic ...Events Archive Worldwide Africa Programme Arab Programme Asia and Pacific Programme Europe and NIS Programme Latin American and Caribbean Programme Least-Developed Countries South-South Cooperation Human Security Directory of Offices Research & Statistics Publications Research and ...

386

The Natural Statistics of Audiovisual Speech

The SCF approximation is used in a statistical theory of melting based on equality of the chemical potentials. The results for the melting points of the inert gases are close to the observed values.

1967-02-01

387

Streams of solid municipal wastes. Evaluation of data on the basis of waste follow-up system; Kiinteaen yhdyskuntajaetteen virrat: aineistotarkastelua jaetealan seurantajaerjestelmaen avulla

Humans, like other animals, are exposed to a continuous stream of signals, which are dynamic, multimodal, extended, and time varying in nature. This complex input space must be transduced and sampled...Full Text Available

2009-07-01

388

Statistical methods for environmental pollution monitoring

The follow-up system for wastes (JAeSTI), developed at the end of the 1990s, forms a basis for today's followup activities in Finland. JAeSTI relies on an environmental protection database, the compliance monitoring system VAHTI operated by the environmental authorities. Waste followup and waste statistics depend very much on the annual waste quantities recorded in the VAHTI system. In the KYJ-project the coverage and reliability of the data in the VAHTI system was evaluated as for the streams of solid municipal waste. The project also included the compiling of national statistics on municipal waste for the year 2000. The project used other information sources, too, such as statistics compiled when the National Waste Plan and regional waste plans were revised in 2002. In addition, the extent and quantity of in-situ (household) composting and incineration were assessed on the basis of a separate study (Annex 2, In ...

2004-07-01

389

Statistical estimation of the lifetimes of charmed particles

This volume covers planning, design, and data analysis. It offers statistical methods for designing environmental sampling and monitoring programs as well as analyzing the resulting data. Statistical sample survey methods to problems of estimating average and total amounts of environmental pollution are presented in detail. The book also provides a broad array of statistical analysis methods for many purposes...numerous examples...three case studies...end-of-chapter questions...computer codes (showing what output looks like along with its interpretation)...a discussion of Kriging methods for estimating pollution concentration contours over space and/or time...nomographs for determining the number of samples required to detect hot spots with specified confidence...and a description and tables for conducting Rosner's test to identify outlaying (usually large) pollution measurements in a data set.

1986-01-01

390

Sample manuscript showing specifications and style - NASA ...

Various statistical methods for the estimation of the mean lifetimes of charmed particles have been considered. It is shown that the usual estimates of the maximum likelihood in some cases do not exist or may have rather great positive bias, if the statistics are low. Alternative estimates of the mean lifetime tau are discussed. Among them the 'jackknife' estimate of tau is considered. The minimum variance unbiased estimates of the average rate of decay 1/tau have been derived for some particular cases. It is also shown that the usual estimate of the ratio of the mean lifetimes of different kinds of particles may also have a bias when the statistics are poor. Two methods of reducing this bias have been proposed.

1984-12-15

391

Reduction of statistic error in Mihalczo subcriticality measurement

Figure 7: Horak Cost Estimating Relationship with Statistical Details. For this comparison, we ignore the Material (glass vs metal) and Design (on vs ...

392

Quantum field theory of particles with braid group statistics in 2+1 dimensions

The theoretical formula for the statistical error estimation in Mihalczo method was derived, and the dependence of the error were investigated on the facility to be measured and on the parameter in the data analysis. The formula was derived based on the reactor noise theory and the error theory for the frequency analysis, and found that the error depends on such parameters as the prompt neutron decay constant, detector efficiencies, and the frequency bandwidth. Statistical errors estimated with the formula was compared with experimental values and verified to be reasonable. Through parameter surveys, it is found that there is an optimum combination of the parameters to reduce the magnitude of the errors. In the experiment performed in DCA subcriticality measurement facility, it is estimated experimentally that the measurement requires 20 minutes to obtain the statistic error of 1% for the keff 0.9. According to the error ...

1998-08-01

393

Physics of chemoreception.

The present thesis is concerned with the local quantum physics of relativistic particles and fields in three space-time dimensions, whose statistics is to be described by a representation of the braid group -- so-called plektons or, if the representation is Abelian, anyons. In particular the issue of the existence of free anyonic fields is addressed. In our context, these are operators affiliated with the 'local' field algebras and creating only single particle vectors from the vacuum. (Localizability here refers to regions extending to infinity in some spacelike direction.) Under a mild regularity condition for these fields, we can derive commutation relations which are not compatible with braid group statistics. Further, model-independent results concerning the PCT operator and the connection of spin and statistics are obtained. Assuming the observable algebra to satisfy the Bisognano-Wichmann theorem, a PCT theorem for ...

1997-01-01

394

On the statistical estimation of the lifetimes of charmed particles

Statistical fluctuations limit the precision with which a microorganism can, in a given time T, determine the concentration of a chemoattractant in the surrounding medium. The best a cell can do is...Full Text Available

1977-11-01

395

Nuclear power plant personnel training in France

Various statistical methods for the estimation of the mean lifetimes of charmed particles have been considered. It is shown that the usual estimates of the maximum likelihood in some cases do not exist or may have rather great positive bias, if the statistics are low. Alternative estimates of the mean lifetime tau are discussed. Among them the 'jackknife' estimate of tau is considered. The minimum variance unbiased estimates of the average rate of decay 1/tau have been derived for some particular cases. It is also shown that the usual estimate of the ratio of the mean lifetimes of different kinds of particles may alos have a bias when the statistics are poor. Two methods of reducing this bias have been proposed. (orig.).

1984-12-15

396

NURE aerial gamma-ray and magnetic reconnaissance survey: southeastern area-Alaska, Port Alexander Quadrangle

Data on French nuclear electricity generation sites, nuclear power plant operations personnel, operation simulators, nuclear training centers and training statistics are presented.

1994-03-21

397

The flight line profile data and statistical analysis results for the Port Alexander Quadrangle in southeast Alaska are presented.

398

Energy statistics manual

Development Statistics for the UH-1 Ada Feasibility Study

Detailed, complete, timely and reliable statistics are essential to monitor the energy situation at a country level as well as at an international level. Energy statistics on supply, trade, stocks, transformation and demand are indeed the basis for any sound energy policy decision. For instance, the market of oil -- which is the largest traded commodity worldwide -- needs to be closely monitored in order for all market players to know at any time what is produced, traded, stocked and consumed and by whom. In view of the role and importance of energy in world development, one would expect that basic energy information to be readily available and reliable. This is not always the case and one can even observe a decline in the quality, coverage and timeliness of energy statistics over the last few years.

2010-07-01

399

Comparing healthcare outcomes.

... to the actual size base on the terminal semicolon counting ... I Queue and stack control. ... analysis: highly accurate analysis of noisy, stochastic data. ...

1992-01-01

400

CHANEXTDFS - Chandra Extended Deep Field South Survey Point Source ...

Governments are increasingly concerned to compare the quality and effectiveness of healthcare interventions but find this a complex matter. Crude hospital statistics can be dangerously misleading and...Full Text Available

1994-06-04

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401

CDC Data & Statistics | Feature: Drowning Risks in Natural Water...

Jan 25, 2006 ... Source positions are determined using matched-filter and centroiding .... The upper 1-sigma statistical error in the full-band counts. ...

402

CBSD Version 2 Component Models of the IR Celestial ...

swimmers in or around the water. Designate a responsible adult who can swim and knows CPR to watch swimmers in or around water. The supervisor should not be involved in any...

2011-09-24

403

A proposition of 3D inertial tolerancing to consider the statistical combination of the location and orientation deviations

... 1-sigma ZOHF pixel-to-plxel statistical fluctuations ... Spatial frequency filtering shows distinct bands, but miss ... LOS emissivity at the point of closest ...

1990-12-07

404

caCORE version 3: Implementation of a model driven, service-oriented architecture for semantic interoperability.

Tolerancing of assembly mechanisms is a major interest in the product life cycle. One can distinguish several models with growing complexity, from 1-dimensional (1D) to 3-dimensional (3D) (including form deviations), and two main tolerancing assumptions, the worst case and the statistical hypothesis. This paper presents an approach to 3D statistical tolerancing using a new acceptance criterion. Our approach is based on the 1D inertial acceptance criterion that is extended to 3D and form acceptance. The modal characterisation is used to describe the form deviation of a geometry as the combination of elementary deviations (location, orientation and form). The proposed 3D statistical tolerancing is applied on a simple mechanism with lever arm. It is also compared to the traditional worst-case tolerancing using a tolerance zone.

2010-01-01

405

New dimensions in our understanding of the human health effects of environmental pollutants

One of the requirements for a federated information system is interoperability, the ability of one computer system to access and use the resources of another system. This feature is particularly important in biomedical research systems, which need to coordinate a variety of disparate types of data. In order to meet this need, the National Cancer Institute Center for Bioinformatics (NCICB) has created the cancer Common Ontologic Representation Environment (caCORE), an interoperability infrastructure based on Model Driven Architecture. The caCORE infrastructure provides a mechanism to create interoperable biomedical information systems. Systems built using the caCORE paradigm address both aspects of interoperability: the ability to access data (syntactic interoperability) and understand the data once retrieved (semantic interoperability). This infrastructure consists of an integrated set of three major components: a controlled terminology service ...

2007-04-02

406

Evaluation of Toll-like receptors 3 (c.1377C/T) and 9 (G2848A) gene polymorphisms in cervical cancer susceptibility

The term {open_quotes}hazardous{close_quotes} waste is used primarily in reference to potential hazards to human health and, to a lesser decree, hazards to wildlife and the ecosystem. Many of the chemicals associated with hazardous waste sites are also widely distributed throughout the environment; therefore, the health hazards associated with hazardous waste sites are not different from those associated with general environmental contamination. Until recently, it was generally assumed that cancer was the human disease of greatest concern associated with toxic chemicals. In fact, most governmental regulations related to exposure are designed on the basis of presumed cancer risks. Since the evidence that hazardous chemicals can cause cancer is strong, it is appropriate to be concerned about cancer risk. Recent evidence, however, has triggered a reevaluation of the assumption that only ...

1996-12-31

407

British Library Electronic Table of Contents (United Kingdom)

Cervical cancer is emerging as a leading cause of morbidity and mortality in women worldwide. Toll-like Receptor (TLR) gene polymorphisms may contribute to subsequent inter-individual variability in cancer susceptibility. The present study aimed to identify the role of TLR 3 (c.1377C/T) [rs3775290] and TLR 9 (G2848A) [rs352140] gene polymorphisms in the risk of developing cervical cancer in North India. Peripheral blood samples were collected from 200 histopathologically confirmed cervical cancer patients from North India and 200 unrelated, cancer-free, age-matched healthy female controls of similar ethnicity. Genomic DNA was extracted using the salting-out method, and genotyped for TLR 3 and TLR 9 using polymerase chain reaction-based restriction fragment length polymorphism (PCR-RFLP). O...

2011-01-01

408

Dietary Cholesterol and Prostate Cancer Risk: Inhibition of prostate Cancer in Rats by the Administration of some Antioxidants

Accuracy of patient dose calculation for lung IMRT: A comparison of Monte Carlo, convolution/superposition, and pencil beam computations

The present work was carried out to illuminate the relation between high cholesterol diet and incidence of prostate caner. Also, in this study, the effect of DHEA, selenium or oxygen therapy were tested in order to show to what extent they are valid to ameliorate the deleterious effects of prostate cancer. The obtained results revealed that prostate cancer caused a significant (p<0.01) elevation of TAP, PAP, PSA, total cholesterol, triglyceride, HDL-cholesterol and LDL-cholesterol and prostate COX-2, whereas, testosterone, free testosterone, DHEA-S, FT_4 and FT_3 were decreased significantly as compared with the corresponding levels in control rats in both normal and high cholesterol diet. Supplementation of DHEA, selenium or oxygen therapy ameliorated all variables recorded herein but, their values did not revert to normal. Any how, the results of this investigation showed that the above mentioned antioxidants possess potential benefits in ...

2009-07-01

409

Detection of mice lung cancer by neutron radiography

The accuracy of dose computation within the lungs depends strongly on the performance of the calculation algorithm in regions of electronic disequilibrium that arise near tissue inhomogeneities with large density variations. There is a lack of data evaluating the performance of highly developed analytical dose calculation algorithms compared to Monte Carlo computations in a clinical setting. We compared full Monte Carlo calculations (performed by our Monte Carlo dose engine MCDE) with two different commercial convolution/superposition (CS) implementations (Pinnacle-CS and Helax-TMS's collapsed cone model Helax-CC) and one pencil beam algorithm (Helax-TMS's pencil beam model Helax-PB) for 10 intensity modulated radiation therapy (IMRT) lung cancer patients. Treatment plans were created for two photon beam qualities (6 and 18 MV). For each dose calculation algorithm, patient, and beam quality, the following set of clinically relevant dose-volume values was reported: ...

2006-09-01

410

A case study of trastuzumab treatment for metastatic breast cancer in pregnancy: fetal risks and management of cerebral metastases

Thermal neutron beam from the TNRF of JRR-3M was utilized for detection of mice lung cancer in vivo. Both the static and real-time neutron imaging were tried. Very strong thermal neutron beam is necessary to detect lung cancers because small changes are hidden by the very large attenuation of thermal neutron beam by the hydrogens in the tissues. The detection was successfully performed. Especially, the Super Eye of Hamamatsu Photonics contributed very effectively. Bone marrows and cartilages were also shown clearly. If an efficient and compact neutron source will become available in future, this method will grow up as a powerful tool for biomedical application. (author).

1995-11-01

411

British Library Electronic Table of Contents (United Kingdom)

Trastuzumab increases survival amongst women with human epidermal growth factor receptor (HER)-2 receptor positive metastatic breast cancer, but maternal and fetal risks are associated with advanced disease and its treatment in pregnancy. We present a case of a primigravid with HER-2 positive metastatic breast cancer who received trastuzumab throughout pregnancy. She presented with cerebral metastases, requiring surgical decompression and resection. Reversible oligohydramnios developed during pregnancy. Fetal safety data on trastuzumab in pregnancy is limited, but case reports suggest a recurring pattern of (mostly reversible) oligohydramnios.

2011-01-01

412

[caCORE: core architecture of bioinformation on cancer research in America].

What Is Most Important to Patients when Deciding about Colorectal Screening?

A critical factor in the advancement of biomedical research is the ease with which data can be integrated, redistributed and analyzed both within and across domains. This paper summarizes the Biomedical Information Core Infrastructure built by National Cancer Institute Center for Bioinformatics in America (NCICB). The main product from the Core Infrastructure is caCORE--cancer Common Ontologic Reference Environment, which is the infrastructure backbone supporting data management and application development at NCICB. The paper explains the structure and function of caCORE: (1) Enterprise Vocabulary Services (EVS). They provide controlled vocabulary, dictionary and thesaurus services, and EVS produces the NCI Thesaurus and the NCI Metathesaurus; (2) The Cancer Data Standards Repository (caDSR). It provides a metadata registry for common data elements. (3) Cancer Bioinformatics Infrastructure Objects ...

2006-04-18

413

Updates on Osteonecrosis of the Jaw

BACKGROUNDColorectal cancer (CRC) screening can be administered through tests with varied characteristics and is a preference-sensitive decision.OBJECTIVETo...Full Text Available

2010-07-01

414

Tumor necrosis factor-? is associated with positive lymph node status in patients with recurrence of colorectal cancer?indications for anti-TNF-? agents in cancer treatment

Purpose of reviewOsteonecrosis of the Jaw (ONJ) in an uncommon condition noted to occur in patients with cancer receiving intravenous bisphosphonates. The etiology...Full Text Available

2010-09-01

415

British Library Electronic Table of Contents (United Kingdom)

Introduction The progressive growth of malignancies is accompanied by a decline in the immune response through mechanisms which are poorly understood. Apoptosis and induction of inflammation by tumor released cytokines as tumor escape mechanisms have been proposed to play an important role in colorectal carcinogenesis. Methods Expression of Tumor necrosis factor-alpha (TNF-?) was analyzed in colorectal cancer specimen and the cancer cell line HT-29 by immunohistochemistry and RT-PCR. TNF-? expression on protein and mRNA level were correlated with clinical characteristics and impact on survival. TNFR-1 was co-labelled with TNF-? and CD8+ cytotoxic T cells in immunofluorescence double staining experiments. Results: 94% (n?=?98/104) of the patients with CRC expressed TNF-?. High TNF-? express...

2011-01-01

416

Towards a more functional concept of causality in cancer research

The pros and cons of phytoestrogens

Advances in molecular technologies challenge the different concepts of causality in biology, epidemiology and multistage mathematical models. The lack of integration of the different aspects of causality...Full Text Available

417

The multiple roles of autophagy in cancer

Phytoestrogens are plant derived compounds found in a wide variety of foods, most notably soy. A litany of health benefits including a lowered risk of osteoporosis, heart disease, breast cancer,...Full Text Available

2010-10-01

418

The Importance of Mitochondrial DNA in Aging and Cancer

Autophagy is an evolutionarily conserved, catabolic process that involves the entrapment of cytoplasmic components within characteristic vesicles for their delivery to and degradation within lysosomes....Full Text Available

2011-07-01

419

Telomeric recombination induced by dysfunctional telomeres

Mitochondrial dysfunction has been implicated in premature aging, age-related diseases, and tumor initiation and progression. Alterations of the mitochondrial genome accumulate both in aging tissue...Full Text Available

420

Telomeres in cancer and ageing

Telomere maintenance is essential for cellular immortality, and most cancer cells maintain their telomeres through the enzyme telomerase. Telomeres and telomerase represent promising anticancer...Full Text Available

2011-01-15

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

421

Telomeres and telomerase in cancer

Telomeres protect the chromosome ends from unscheduled DNA repair and degradation. Telomeres are heterochromatic domains composed of repetitive DNA (TTAGGG repeats) bound to an array of specialized...Full Text Available

2011-01-12

422

Spectral Analysis of Breast Cancer on Tissue Microarrays ...

Myriad genetic and epigenetic alterations are required to drive normal cells toward malignant transformation. These somatic events commandeer many signaling pathways that cooperate to endow aspiring...Full Text Available

2010-01-01

423

Site-Specific Methylation of the Promoter Alters Deoxyribonucleic Acid-Protein Interactions and Prevents ...

... Although cytologic evaluation of urine specimens is a standard Cesar Angeletti, MD ... 3. Rodriguez-Alonso A, Pita-Fernandez S, Gonzalez-Carrero J, ...

2005-04-01

424

Sirtuins, Bioageing, and Cancer

... and R. L. Momparler. DNA methylation of retinoic acid receptor beta in breast cancer and possible therapeutic role of ... ...

425

Role of early phase helical CT images in the evaluation of wall invasion of colorectal cancer. Pathological correlation

The Sirtuins are a family of orthologues of yeast Sir2 found in a wide range of organisms from bacteria to man. They display a high degree of conservation between species, in both sequence and function,...Full Text Available

426

Regulation of Senescence in Cancer and Aging

The usefulness of helical CT early phase images optimized by the SmartPrep method for evaluation of wall invasion by colorectal cancer was investigated. Between August 1997 and September 1998, CT was performed to evaluate the primary tumor and local extension in 10 consecutive patients with colorectal cancer confirmed by barium enema- and/or colonoscopy. Early-phase images were acquired by using SmartPrep application software. This method allows the optimal scan delay time to be obtained by continuous monitoring of increases in CT values after injection of contrast medium. Sections of the surgical specimens, close to the same plane as the CT images, and of the same slice thickness, were analyzed histopathologically. All 10 cancers, regardless of size, showed strong enhancement on the early-phase images (81.4-112 HU, mean: 95.1 HU). The strongly enhanced image areas on CT corresponded to the primary ...

2000-02-01

427

Recent advances in the management of carcinoma of the rectum

Senescence is regarded as a physiological response of cells to stress, including telomere dysfunction, aberrant oncogenic activation, DNA damage, and oxidative stress. This stress response has an antagonistically...Full Text Available

428

In the last two decades rectal cancer has changed from a surgically managed disease into a multidisciplinary treatment model resulting in considerable improvements in the survival and outcome. This...Full Text Available

429

Ras history

Radiolabelled peanut lectin for the scintigraphy detection of cancer

Although the roots of Ras sprouted from the rich history of retrovirus research, it was the discovery of mutationally activated RAS genes in human cancer in 1982 that stimulated an...Full Text Available

2010-07-01

430

Prognostic Factors for Failure after Prostatectomy

To investigate the role of intravenously administered, radioiodinated peanut lectin ("1"3"1I-PNA) in the non-invasive detection of cancer, the pharmacokinetics and scintigraphic distribution of this novel tumor-seeking compound were studied in 8 patients with metastatic cancer of the colon, breast or lung. Scintigraphic localization of "1"3"1I-PNA was apparent at certain anatomical sites of known metastases in 2 patients and in a further 2 patients an adjacent malignant pleural effusion was visualized. The rapid clearance of radioactivity from the whole body and plasma with marked renal concentration and rapid urinary excretion of significant amounts of intact "1"3"1I-PNA (mol.wt. 107,000,pI 5.95) implied that this molecule was excreted selectively by the renal tubules. PNA or other lectins may find a role in the scintigraphic detection of selected types of cancer. (author).

1984-01-01

431

Primary lymphoma of the brain: MedlinePlus Medical Encyclopedia

Several randomized studies have been completed in prostate cancer that show a benefit to immediate postoperative treatment in patients undergoing prostatectomy. In one of the studies, there was even...Full Text Available

432

Preclinical Models for Neuroblastoma: Establishing a Baseline for Treatment

brain Printer-friendly version Email this page to a friend Share Primary lymphoma of the brain is cancer of the lymph cells that starts in the brain. Causes The cause of primary...

2011-10-13

433

Polymorphisms in fatty acid metabolism-related genes are associated with colorectal cancer risk

BackgroundPreclinical models of pediatric cancers are essential for testing new chemotherapeutic combinations for clinical trials. The most widely used ...Full Text Available

434

DEFF Research Database (Denmark)

Colorectal cancer is the third most common malignant tumor and the fourth-leading cause of cancer death worldwide. The crucial role of fatty acids for a number of important biological processes suggests a more in depth analysis of inter-individual differences in fatty acid metabolizing genes as contributing factor to colon carcinogenesis. We examined the association between genetic variability in 43 fatty acid metabolism-related genes and colorectal risk in 1225 CRC cases and 2032 controls participating in the European Prospective Investigation into Cancer and Nutrition study. 392 single nucleotide polymorphisms were selected using pairwise tagging with an r(2) cutoff of 0.8 and a minor allele frequency of >5%. Conditional logistic regression models were used to estimate odds ratios and corresponding 95% confidence intervals. Haplotype analysis was performed using a generalized linear model framework. On the genotype ...

2010-01-01

435

Peritonectomy procedures.

Oral Exposure to Bisphenol A Increases Dimethylbenzanthracene-Induced Mammary Cancer in Rats

OBJECTIVE: New surgical procedures designed to assist in the treatment of peritoneal surface malignancy were sought. BACKGROUND: Decisions regarding the treatment of cancer depend on the anatomic location...Full Text Available

1995-01-01

436

Novel Magnetic Fluids for Breast Cancer Therapy

BackgroundBisphenol A (BPA) is widely used in the manufacture of polycarbonate plastics, including infant formula bottles.ObjectivesBased on the...Full Text Available

2009-06-01

437

Novel Cytotoxic Vectors Based on Adeno-Associated Virus

... metal-oleate complexes. At this point, this method has been reported only for iron nanoparticles [15]. We have demonstrated ...

2008-01-01

438

Monoclonal antibodies: new agents for cancer detection and targeted therapy

positive primary PymT breast cancer cells in primary co-cultured tumor tissue, suggesting target specificity of

439

Molecular marks for epigenetic identification of developmental and cancer stem cells

Antibodies directed against markers on cancer cells are gaining in importance for the purpose of targeting diagnostic and therapeutic agents. In the past, this approach has had very limited success principally because the classical methods for producing antibodies from blood serum of animals immunized with cancer cells or extracts were unsatisfactory. The situation has changed dramatically since 1975 following the design of procedures for 'immortalizing' antibody-producing cells (lymphocytes) by fusing them with cultured myeloma cells to form hybridomas which continuously secrete antibodies. Since these hybridomas produce antibodies coded for by a single antibody-producing cell, the antibodies are called monoclonal. Building on these advances in biomedical research, it is now possible to reproducibly manufacture monoclonal antibodies on a scale suitable for use in cancer detection and therapy.

440

British Library Electronic Table of Contents (United Kingdom)

Epigenetic regulations of genes by reversible methylation of DNA (at the carbon-5 of cytosine) and numerous reversible modifications of histones play important roles in normal physiology and development, and epigenetic deregulations are associated with developmental disorders and various disease states, including cancer. Stem cells have the capacity to self-renew indefinitely. Similar to stem cells, some malignant cells have the capacity to divide indefinitely and are referred to as cancer stem cells. In recent times, direct correlation between epigenetic modifications and reprogramming of stem cell and cancer stem cell is emerging. Major discoveries were made with investigations on reprogramming gene products, also known as master regulators of totipotency and inducer of pluoripotency, na...

2011-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

441

Modeling survival in colon cancer: a methodological review

Management of Concomitant Cancer and Abdominal Aortic Aneurysm

The Cox proportional hazards model is the most widely used model for survival analysis because of its simplicity. The fundamental assumption in this model is the proportionality of the hazard function....Full Text Available

442

Liver Carcinogenesis Unit

Background. The coexistence of neoplasm and abdominal aortic aneurysm (AAA) presents a real management challenge. This paper reviews the literature on the prevalence, diagnosis,...Full Text Available

443

Lipiodol solution of a lipophilic agent, {sup 188}Re-TDD, for the treatment of liver cancer

The Liver Carcinogenesis Section uses the modern technologies of molecular biology, cell biology, protein chemistry and genetics to investigate the biochemical and genetic pathways involved in human liver cancer.

444

Lack of Association of the Genotype in the GNAS Fok I Polymorphism and Prostate Cancer

Radiolabeled lipiodol has been used for targeting liver cancer. We developed a lipiodol solution of {sup 188}Re-TDD (2,2,9,9-tetramethyl-4,7-diaza-1,10-decanedithiol) and investigated its feasibility for the treatment of liver cancer. The lipiodol solution of {sup 188}Re-TDD was well-retained in the lipiodol phase in vitro. After injection through the tail veins of mice, high lung-uptake was investigated which is evidence of embolizing activity. We also found high accumulation in hepatoma after injection through the hepatic arteries of hepatoma-bearing rats. In conclusion, the lipiodol solution of {sup 188}Re-TDD is a promising agent for liver cancer therapy.

2001-02-01

445

British Library Electronic Table of Contents (United Kingdom)

Abstract Background: G proteins are ubiquitously expressed signal transduction proteins playing a key role in multiple signal transduction pathways. The Gas subunit has been considered as an apoptosis factor. In this study the role of GNAS T393C genotypes of the GNAS gene encoding Gas was analyzed for its influence on the development and progression of prostate cancer. Methods: Genotyping of the GNAS T393C polymorphism in 196 prostate cancer patients and 200 healthy controls was performed by DNA extraction followed by PCR and restriction analysis. Results: We observed no evidence of effects related to GNAS T393C genotype as demonstrated by a comparison of the genotype distribution in prostate cancer patients and healthy controls, the genotype distribution dependent on grade of the primary ...

2011-01-01

446

Isoprinosine augmentation of phytohemagglutinin-induced lymphocyte proliferation.

Interdisciplinary Breast Cancer Training Program

The need for agents designed to modify immune response in the treatment of patients with viral infection, immunodeficiency, or cancer prompted the present study on the mechanisms of action of isoprinosine,...Full Text Available

1976-02-01

447

Growth of mammary epithelial cells in breast-cancer biopsies correlates with EGF binding

... equal volume of vehicle, sesame oil only (n = 10). At 75 days 2.0. ... thracene IDMBA) and sesame oil were purchased from Sigma ...

2005-09-01

448

Four faces of cellular senescence

In order to understand the role of EGF in the development of human mammary epithelial tissue, we analysed the binding of /sup 125/I-EGF to sections of breast cancer biopsies. A mean specific /sup 125/I-EGF binding of 8.9 fmol per mg protein was estimated in thin sections of 17 breast cancer biopsies. Microautoradiographic analysis of /sup 125/I-EGF binding to the tissue sections was applied to demonstrate that EGF was bound predominantly to mammary epithelial cells. The binding was clearly correlated to the number of mitoses of mammary epithelial cells in the same samples. The highest EGF binding and proliferation rates were found in biopsies from breast cancer with axillary lymph-node metastases.

1987-03-15

449

Effect of Smoking Scenes in Films on Immediate Smoking

Cellular senescence is an important mechanism for preventing the proliferation of potential cancer cells. Recently, however, it has become apparent that this process entails more than a simple cessation...Full Text Available

2011-02-21

450

Effect of COX-2 (PGE2) and IL-6 on Prostate Cancer Bone ...

BackgroundThe National Cancer Institute has concluded that exposure to smoking in movies causes adolescent smoking and there are similar results for young adults.Full Text Available

2010-04-01

451

EMFs: cutting through the controversy.

... of the AR (25). Dihydrotestosterone increases Wnt signaling activity in preosteoblasts. Functional interactions between ...

2008-02-02

452

Dysregulation of the mevalonate pathway promotes transformation

SOME SCIENTISTS ALLEGE that exposure to electric and magnetic fields generated by electric power delivery systems is responsible for certain cancers (particularly among children), reproductive dysfunction,...Full Text Available

1996-05-01

453

Distribution of domestic radon concentrations and lung cancer mortality in England and Wales

The importance of cancer metabolism has been appreciated for many years, but the intricacies of how metabolic pathways interconnect with oncogenic signaling are not fully understood. With a clear understanding...Full Text Available

2010-08-24

454

Using aggregate data for the counties of England and Wales, a negative association is found between mean radon concentrations in dwellings and lung cancer standardised mortality ratios, when regional smoking variations, diet variations, social class variations and population density are controlled. Cornwall and Devon have the highest mean domestic radon gas concentrations, yet the number of lung cancer deaths there was within the range to be expected from relationships not involving radon observed in the rest of the country. While high values of radon exposure appear to concentrate in particular localities, the variations in lung cancer mortality between districts in Cornwall and Devon are small. These findings do not refute the linear exposure-risk hypothesis, but the evidence suggests that relatively few, if any, radon related deaths were associated with the dwellings where radon gas concentrations exceed the recommended ...

1988-01-01

455

Colonoscopy

Cell proliferation and chemical carcinogenesis: symposium overview.

... experts agree-- a colonoscopy is the most accurate test to detect the cancer, but because of cost ... method. Dr. Randall Burt: Colonoscopy is the best test. The question is therefore shouldn't everyone, since ...

456

Carcinogens and cancers in freshwater fishes.

Cancer, by definition, is a proliferative disease. The fundamental scientific issue explored at the international symposium "Cell Proliferation and Chemical Carcinogenesis" was the impact of chemically...Full Text Available

1993-12-01

457

Cancer-cell-specific cytotoxicity of non-oxidized iron elements in iron core-gold shell NPs

Epizootics of neoplasms in freshwater fish species are considered in relation to circumstantial and experimental evidence that suggest that some epizootics of neoplasia of hepatocellular, cholangiocellular,...Full Text Available

1991-01-01

458

British Library Electronic Table of Contents (United Kingdom)

Gold-coated iron nanoparticles (NPs) selectively and significantly (P <0.0001) inhibit proliferation of oral- and colorectal-cancer cells in vitro at doses as low as 5 mg/mL, but have little adverse effect on normal healthy control cells. The particle treatment caused delay in cell-cycle progression, especially in the S-phase. There was no significant difference in the NP uptake between cancer and control cells, and cytotoxicity resulted primarily from the iron core, before oxidation, rather than from the Fe ions released from the core. In contrast with magnetic NPs that usually serve as drug carriers, diagnostic probes or hyperthermia media, the iron, before oxidation, in the NPs selectively suppressed cancer cell growth and left healthy control cells unaffected in vitro and in vivo. This...

2011-01-01

459

Cancer gene discovery in mouse and man

AbstractThe elucidation of the human and mouse genome sequence and developments in high-throughput genome analysis, and in computational tools, have made it possible to profile entire...Full Text Available

2009-12-01

460

Breast Cancer Treatment

Body mass index and risk of colorectal cancer in Chinese Singaporeans

... mammography or on ultrasound but not found on physical examination, we consider them non-palpable or not ... lot of this. We send every patient for physical therapy, no matter what type of reconstruction we ...

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

461

British Library Electronic Table of Contents (United Kingdom)

AbstractBACKGROUND: The authors chose to examine the association between body mass index (BMI) and incident colorectal cancer across the spectrum of BMI, including underweight persons, because detailed prospective cohort data on this topic in Asians is scarce, as is data on underweight persons (BMI, <18.5 kg/m2) in any population. METHODS: Analysis of the Singapore Chinese Health Study included 51,251 men and women aged 45-74 years enrolled in 1993-1998 and followed through 2007. Incident cancer cases and deaths among cohort members were identified through record linkage, and 980 cases were identified. Cox regression models were used to investigate the association of baseline BMI with risk of incident colorectal cancer during a mean of 11.5 years of follow-up. RESULTS: A significant, U-sha...

2011-01-01

462

Attributes of Interactive Online Health Information Systems

Arterial and Venous Thrombosis in Cancer Patients

The development of online communication systems related to prevention, decision making, and coping with cancer has outpaced theoretical attention to the attributes that appeal to system...Full Text Available

463

Antitumor Activity of Noscapine in Combination with Doxorubicin in Triple Negative Breast Cancer

The most frequent ultimate cause of death is myocardial arrest. In many cases this is due to myocardial hypoxia, generally arising from failure of the coronary macro- and microcirculation to deliver...Full Text Available

464

Anesthetic considerations of central airway obstruction

BackgroundThe aim of this study was to investigate the anticancer activity and mechanism of action of Noscapine alone and in combination with Doxorubicin against triple negative...Full Text Available

465

Adenopathies in lung cancer: a comparison of pathology, Computed Tomography and endoscopic ultrasound findings

Central airway obstruction (CAO) is a serious presentation of lung cancer and associated chest diseases. It presents a real challenge to the anesthesiologist because usually the patient admitted to...Full Text Available

2011-07-01

466

APOPTOSIS BY DIETARY AGENTS FOR PREVENTION AND TREATMENT OF CANCER

A prospective comparative study with pathology was performed to assess the clinical value of Computed Tomography (CT) and endoscopic ultrasound (EUS) for nodal staging in lung cancer. A total of 329 nodal stations were dissected or sampled and 755 lymph nodes were examined at histology. On a pre-station basis, CT had greater sensitivity (74%) than EUS (56%), but EUS was more specific (83% versus 93%). The accuracy rates of the two techniques were similar. In conclusion, endoscopic ultrasound should be part of a routine preoperative diagnostic approach to non-small-cell lung cancer., because of its high specificity. Results can be improved when EUS and CT are combined., which suggests that these imaging modalities should be used together in selected patients for the noninvasive staging of non-small-cell lung cancer to identify local lymphatic spread.

1999-01-01

467

A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Advanced Solid Tumors and Metastatic Brain Cancer

The role of apoptosis or programmed cell death in the regulation of development and maintenance of homeostasis in multicellular organisms is well established. During the last decade, naturally...Full Text Available

2008-12-01

468

The effects of soil type and chemical treatment on nickel speciation in refinery enriched soils: A multi-technique investigation

Advanced Solid Tumors With and Without Brain Metastases

2010-06-03

469

British Library Electronic Table of Contents (United Kingdom)

Aerial deposition of Ni from a refinery in Port Colborne, Ontario, Canada has resulted in the enrichment of 29km2 of land with Ni concentrations exceeding the Canadian Ministry of the Environment's remedial action level of 200mgkg-1. Several studies on these soils have shown that making the soils calcareous was effective at reducing chemically extractable Ni, as well as alleviating Ni phytotoxicity symptoms in vegetable crops grown in the vicinity of the refinery. Conversely, dolomitic limestone additions resulted in increased uptake of Ni in the Ni hyperaccumulator Alyssum murale `Kotodesh', a plant whose use was proposed as a remediation strategy for this area. In this paper we use multiple techniques to directly assess the role soil type and lime treatments play in altering the speciati...

2007-01-01

470

Research and development environmental activities at CANMET; Les activites environnementales de R et D chez CANMET

Psychometric properties of a scale measuring negative attitudes toward overweight individuals.

The Canada Centre for Mineral and Energy Technology (CANMET) is a research organization dedicated to the advancement of the Canadian mining industry. It specializes in the development of new technologies and the coordination of scientific partnerships in the fields of mines, metallurgical processes, and the environment. CANMET supports a number of research and development activities related to the mining industry. In this poster presentation, the author described the mandate of CANMET by first introducing the organization chart with a special emphasis placed on the Mining and Mineral Sciences Laboratories. A description of the different types of partnerships was included, followed by specific details concerning all the projects related to the mining industry, such as terrain control, automation of mines, underground mining environment, processes and services, analytical support, environmental programs, mine effluent, waste rock and tailings, and metals and the ...

2000-07-01

471

Proceedings of the PHEV 2007 conference : where the grid meets the road

This study examined the psychometric properties of the Anti-fat Attitudes Scale (AFAS), a 5-item instrument developed by the authors to measure negative attitudes toward overweight individuals. A total of 4 studies were conducted among Canadian adolescents (n = 1,452) and university students (n = 424). Results suggested that the AFAS possessed a unidimensional factor structure and satisfactory reliability for both men and women. As predicted, men obtained higher scores than women on the AFAS, and antifat attitudes were positively associated with authoritarianism, homonegativity, and political conservatism. Participants who were overweight had lower scores on the AFAS than participants who were thin or average weight. Responses on the AFAS did not appear to be contaminated by social desirability bias. PMID:10457760

1999-08-01

472

Proceedings of the Canadian Society for Bioengineering CSBE/SCGAB 2006 national technical conference

This conference examined the potential role of plug-in hybrid electric vehicles (PHEVs) which are gaining interest around the world. Emerging PHEV technologies were reviewed along with the role that biofuels and electricity play in their widespread use. It was attended by members of industry, academia, utilities, government and institutions to review on-going research and demonstrations of PHEV projects across North America. The purpose was to understand how PHEV technologies can be integrated into current and future transportation systems and the electrical power grid. Other objectives were to establish a primarily-Canadian network focused on PHEV-related issues to promote public engagement for the plug-in highway. The possible role of government support for PHEV research, development and commercialization was also discussed. In addition to workshops and poster sessions, this conference featured 75 presentations, of which 37 have been catalogued separately for ...

2007-11-01

473

This conference provided a forum for discussing advances in the application of engineering principles and practices dealing with biological systems for the production of food, bioproducts and energy. The discussions focused on engineering practices in agriculture, forestry, bioresources, biochemistry and biosystems. The sessions of the conference were entitled: renewable energy and biofuels; food and bioproducts; odour and greenhouse gases; soil and water; waste management and bioresiduals; animal welfare and production; grain storage; machinery systems; structures and biocomposites; and, agricultural production. The conference also featured a workshop on modeling material and energy flows through agro-ecosystems. In addition to 22 posters, the conference featured 100 presentations, of which 8 have been catalogued separately for inclusion in this database. refs., tabs., figs.

2006-07-01

474

Korea's Team CANDU

Hydrogen absorption behavior of Zr-2.5Nb pressure tubes in Wolsung Unit 1

KEPCO (Korean Electric Power Corp.) with the support of AECL and other Korean and Canadian subcontractors has created a strong multi-company team to execute design and construction of the Wolsung-2 CANDU 6 power plant. Key concepts of the project team are: 1. KEPCO is the project manager, and AECL is the major engineering and supply contractor; 2. Significant participation by Korean companies in design work in Canada and Korea; 3. Significant manufacturing in both Canada and Korea; 4. Construction by Korean contractors. Key concepts of the Wolsung 2 design are: 1. Evolutionary improvement of the Wolsung-1 plant which balances proven technology and necessary design improvements including current codes and standards. 2. Sharing some structures with the Wolsung-1 plant. This paper describes the successful establishment and operation of the complex project interfaces along with the current project status and plans.

1992-06-07

475

Highlights from the III International Symposium of Thrombosis and Anticoagulation (ISTA), October 14?16, 2010, S?o Paulo, Brazil

The deuterium uptake behavior of Zr-2.5Nb pressure tubes in Wolsung Unit 1 was analyzed in terms of longitudinal location, operation time, and coolant temperature. The results were compared with those obtained from Canadian CANDU reactors. The amount of deuterium uptake was higher at the outlet part than at the inlet part and was also higher when subjected to a longer operation time and a higher coolant temperature. The hydrogen uptake of Zr-2.5Nb in a hydrogen gas atmosphere was dependent on the microstructure of the alloy. The aged Zr-2.5Nb consisting of {alpha}-Zr and {beta}-Zr phases. The hydrogen in the alloy decreased the rate of oxidation. This could be explained in terms of the cathodic controlled reaction of Zr-2.5Nb oxidation. (author)

1998-08-01

476

British Library Electronic Table of Contents (United Kingdom)

To discuss and share knowledge around advances in the care of patients with thrombotic disorders, the Third International Symposium of Thrombosis and Anticoagulation was held in S?o Paulo, Brazil, from October 14?16, 2010. This scientific program was developed by clinicians for clinicians, and was promoted by four major clinical research institutes: the Brazilian Clinical Research Institute, the Duke Clinical Research Institute of the Duke University School of Medicine, the Canadian VIGOUR Centre, and the Uppsala Clinical Research Center. Comprising 3?days of academic presentations and open discussion, the symposium had as its primary goal to educate, motivate, and inspire internists, cardiologists, hematologists, and other physicians by convening national and international visionaries, th...

2011-01-01

477

Generalized Linear Models in Family Studies

Evaluation of soil moisture derived from passive microwave remote sensing over agricultural sites in Canada using ground-based soil moisture monitoring networks

Generalized linear models (GLMs), as defined by J. A. Nelder and R. W. M. Wedderburn (1972), unify a class of regression models for categorical, discrete, and continuous response variables. As an extension of classical linear models, GLMs provide a common body of theory and methodology for some seemingly unrelated models and procedures, such as the logistic, Poisson, and probit models, that are increasingly used in family studies. This article provides an overview of the principle and the key components of GLMs, such as the exponential family of distributions, the linear predictor, and the link function. To illustrate the application of GLMs, this article uses Canadian national survey data to build an example focusing on the number of close friends among older adults. The article concludes with a discussion of the strengths and weaknesses of GLMs.

2005-11-01

478

British Library Electronic Table of Contents (United Kingdom)

Passive microwave soil moisture datasets can be used as an input to provide an integrated assessment of climate variability as it relates to agricultural production. The objective of this research was to examine three passive microwave derived soil moisture datasets over multiple growing seasons in contrasting Canadian agricultural environments. Absolute and relative soil moisture was evaluated from two globally available datasets from the Advanced Microwave Scanning Radiometer for EOS (AMSR-E) sensor using different retrieval algorithms, as well as relative soil wetness at a weekly scale from the Special Sensor Microwave/Imager (SSM/I) sensor. At a daily scale, the Land Parameter Retrieval Model (LPRM) provides a better estimate of surface soil moisture conditions than the National Snow a...

2010-01-01

479

Environmental Radiation Effects: A Need to Question Old Paradigms

Development of reliability-based design and assessment standards for onshore gas transmission pipelines

A historical perspective is given of the current paradigm that does not explicitly protect the environment from radiation, but instead, relies on the concept that if dose limits are set to protect humans then the environment is automatically protected as well. We summarize recent international questioning of this paradigm and briefly present three different frameworks for protecting biota that are being considered by the U.S. DOE, the Canadian government and the International Commission on Radiological Protection. We emphasize that an enhanced collaboration is required between what has traditionally been separated disciplines of radiation biology and radiation ecology if we are going to properly address the current environmental radiation problems. We then summarize results generated from an EMSP grant that allowed us to develop a Low Dose Irradiation Facility that specifically addresses effects of low-level, chronic irradiation on multiple levels of biological ...

2003-03-27

480

De-icing technologies: Introduction to Manitoba Hydro's use of ice melting and ice rolling technologies to remove ice from subtransmission and 115 kV transmission lines

Onshore pipelines have traditionally been designed with a deterministic stress based methodology. The changing operating environment has however imposed many challenges to the pipeline industry, including heightened public awareness of risk, more challenging natural hazards and increased economic competitiveness. To meet the societal expectation of pipeline safety and enhance the competitiveness of the pipeline industry, significant efforts have been spent for the development of reliability-based design and assessment (RBDA) methodology. This paper will briefly review the technology development in the RBDA area and the focus will be on the progresses in the past years in standard development within the American Society of Mechanical Engineers (ASME) and the Canadian Standard Association (CSA) organizations. (author)

2005-07-01

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481

Canadian soil quality criteria for lead, copper, arsenic, cadmium and mercury

Manitoba Hydro's Ice Storm Management Program to reduce ice damage to overhead power lines in the voltage range of 8 kV to 115 kV is described. Overhead power lines are de-iced either by AC ice melting, which involves placing a three-phase short at a calculated point, or ice rolling, which is a process of mechanically stripping ice from conductors. Direct current heating and underground distribution systems are also accepted prevention measures. Advantages and disadvantages of each of these methods of de-icing are reviewed. Material for this paper has been extracted from a workshop manual prepared for the 1993 and 1998 Ice Storm Management workshops organized by Manitoba Hydro through the Canadian Electrical Association. 1 ref.

1999-03-29

482

Beneficial management practices and mitigation of greenhouse gas emissions in the agriculture of the Canadian Prairie: a review

National soil quality criteria for the protection of ecological receptors, including livestock and wildlife, are currently under development in Canada. Based on an evaluation of direct soil contact and soil and food ingestion pathways for sensitive species, soil quality criteria for lead, copper, arsenic, cadmium and mercury for three land use categories have been derived. The draft values, in mg/kg soil, for agricultural, residential/parkland, commercial/industrial land uses are: mercury, 4, 4, 30; copper, 62, 62, 100; cadmium, 10, 10, 27; lead, 70, 250, 400; arsenic, 17, 17, 26. Critical data requirements in developing soil quality criteria are also reviewed.

1995-12-31

483

British Library Electronic Table of Contents (United Kingdom)

Climate change is one of the main global issues of modern time. Ever increasing demand for food/feed and the need for higher environmental standards require shaping of the agricultural activities toward ecological and more sustainable efficient systems. One of the principal ways of attaining higher productivity and environmental standards is identification and adoption of beneficial management practices (BMP) by reviewing the conventional agricultural activities. The BMP are agricultural practices that promote sustainable land stewardship and maintain/increase profitability of farms. The BMP are from both crop and animal production systems and tradeoffs between the two systems could provide several opportunities in reducing, removing and/or avoiding of greenhouse gases (GHG) emissions. Des...

2011-01-01

484

Anderson introduces a new biomass baler

Canadian-based Anderson Group Company has developed an innovative round baler for harvesting a large variety of woody biomass. The baler was initially developed in 2005 in collaboration with the University Laval and Agriculture and Agri-Food Canada. The third generation BIOBALER{sup TM} is currently built, engineered and commercialized by Anderson. It can produce up to 40 bales/hr in short rotations woody crops such as willow and hybrid poplar. The unit can harvest brushes up to 125 mm in diameter. A standard tractor can pull the BIOBALER in fallow or abandoned land, under power transmission lines, and between planted trees. The patented BIOBALER includes a mulcher head attachment, a choice of long or short swivel tongue, a fixed chamber and an undercarriage frame.

2010-07-01

485

Achieving success abroad

1982 International Geoscience and Remote Sensing Symposium, Munich, West Germany, June 1-4, 1982, Digest. Volumes 1 and 2

Department of Foreign Affairs and International Trade services designed to assist businesses to effectively operate in global markets, were described. The goal of the Department is to give strategic targeted information that extends beyond export opportunities to include market access, investment, strategic alliances, technology transfer and competitiveness issues. These services constitute the Department`s Trade Commissioner Service, a network of 600 officers, deployed in 128 embassies and consulates worldwide to support Canadian business development initiatives across 16 sectors of the government`s International Trade Business Plan (ITBP). The Trade Commissioner Service programs include the WIN exporters database, a trade inquiries sourcing team, International Financial Institutions (IFI) projects, and the Program for Export Market Development (PEMD). A series of Sectoral Advisory Groups on International Trade (SAGIT) have been established to facilitate the needs ...

1995-12-31

486

Tube problems: worldwide statistics reviewed

Theoretical and experimental data which have defined and/or extended the effectiveness of remote sensing operations are explored, with consideration given to both scientific and commercial activities. The remote sensing of soil moisture, the sea surface, and oil slicks is discussed, as are programs using satellites for studying geodynamics and geodesy, currents and waves, and coastal zones. NASA, Canadian, and Japanese radar and microwave passive and active systems are described, together with algorithms and techniques for image processing and classification. The SAR-580 project is outlined, and attention is devoted to satellite applications in investigations of the structure of the atmosphere, agriculture and land use, and geology. Design and performance features of various optical scanner, radar, and multispectral data processing systems and procedures are detailed.

1982-01-01

487

The world energy consumption in 2001. Statistical yearbook ENERDATA 2002

EPRI's Steam Generator Strategic Management Project issues an annual report on the progress being made in tackling steam generator problems worldwide, containing a wealth of detailed statistics on the status of operating units and degradation mechanisms encountered. A few highlights are presented from the latest report, issued in October 1993, which covers the period to 31 December 1992. (Author).

488

Technical Documentation and Verification for the Buildings Module in the Visual Sample Plan (VSP) Software

Statistical data on the world energy consumption are given to illustrate the following situation in 2001: the deceleration of the world economic growth and the high prices of oil slowed down the progression of the energy consumption: 0,7 % in 2001; stagnation of the gas and oil consumption and strong progression for coal and electricity in 2001; the deceleration for gas marks a strong inflection compared to the past trends. (A.L.B.)

2002-07-01

489

Statistical support document for proposed effluent limitations guidelines and standards for the pulp, paper, and paperboard. Point source category

Visual Sample Plan (VSP) is an easy-to-use visual and graphic statistically-based software tool being developed by the Pacific Northwest National Laboratory (PNNL) to help determine the appropriate number and location of environmental samples so that environmental decisions can be made with the required confidence. The VSP software, which is available free at http://dqo.pnl.gov/vsp, is a significant aid in developing probability-based sampling designs (number and location of samples and measurements) using the Data Quality Objectives (DQO) planning process developed by the U.S. Environmental Protection Agency (EPA). VSP also has the capability of conducted statistical analyses to provide descriptive statistical summaries of data sets, to test whether data are normally distributed, and to compute upper confidence limits on means. This report is the latest in a series of reports that document the ...

2005-06-30

490

Statistical study of pulsar rotational braking

The document describes the statistical analyses of data on pollutant loadings in effluent wastestreams from pulp, paper, and paperboard facilities. Included are the analyses that support the revised subcategorization and proposed effluent limitations for biochemical oxygen demand and total suspended solids based upon the best practicable control technology currently available.

1993-11-01

491

Statistical mapping analysis of serotonin synthesis images generated in healthy volunteers using positron-emission tomography and alpha-[11C]methyl-L-tryptophan.

Pacini (1973) has considered basic theoretical expectations regarding the magnetic dipole radiation and unipolar induction of pulsars, taking into account observational results. The present investigation is concerned with the difference between the two braking mechanisms. Attention is also given to a statistical study involving a comparison of the two braking mechanisms with observations. The study makes use of the observational data for the distribution of apparent beamwidth, and a geometrical method. The obtained results agree with the theory of magnetic dipole radiation.

492

Software for Data Analysis Programming with R

OBJECTIVES: To assess the suitability of analyzing functional images of brain serotonin (5-HT) synthesis with statistical parametric mapping (SPM), and to investigate further possible sex-related regional...Full Text Available

2000-09-01

493

Monthly energy review, October 1998

Although statistical design is one of the oldest branches of statistics, its importance is ever increasing, especially in the face of the data flood that often faces statisticians. It is important to recognize the appropriate design, and to understand how to effectively implement it, being aware that the default settings from a computer package can easily provide an incorrect analysis. The goal of this book is to describe the principles that drive good design, paying attention to both the theoretical background and the problems arising from real experimental situations. Designs are motivated t

2008-01-01

494

The Monthly Energy Review (MER) presents an overview of the Energy Information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. 37 figs., 61 tabs.

1998-10-01

495

Monthly Energy Review

Generalized supersymmetry on Riemann surfaces and the associated string models

This publication presents an overview of the Energy information Administration`s recent monthly energy statistics. The statistics cover the major activities of US production, consumption, trade, stocks, and prices for petroleum, natural gas, coal, electricity, and nuclear energy. Also included are international energy and thermal and metric conversion factors. Two brief ``energy plugs`` (reviews of EIA publications) are included, as well.

1996-05-28

496

Electricity supply in the United Kingdom. Brief details and statistics

The authors propose a generalization of the concept of supersymmetry non Riemann surfaces. Generators of this symmetry intermix M fields of different spin. Two types of statistics, i.e., bosonic and fermionic statistics, are allowed for parameters of infinitesimal transformations. They also study the possibility of string models associated with these symmetries. The algebraic structure of a part of generalized supersymmetry is regarded as a sort of an M-th root of the Virasoro algebra.

1988-11-01

497

ADAPTATION OF THE ADVANCED STATISTICAL TRAJECTORY REGIONAL AIR POLLUTION (ASTRAP) MODEL TO THE EPA VAX COMPUTER - MODIFICATIONS AND TESTING

Statistical detail is given of the electricity generation and transmission systems in the UK. Breakdown by type of station, by fuel and the proportion generated by others apart from the generating or area boards is presented. Figures are provided for the various high voltage transmission lines in terms of route and circuit length as well as the number of towers and the capacity of mains transformers.

1987-06-01

498

A statistical study of pulsar rotational braking

The Advanced Statistical Trajectory Regional Air Pollution (ASTRAP) model simulates long-term transport and deposition of oxides of and nitrogen. t is a potential screening tool for assessing long-term effects on regional visibility from sulfur emission sources. owever, a rigorou...

499

A statistical pattern recognition paradigm for structural health monitoring

A previous study described the basic theoretical expectations of the magnetic dipole radiation and unipolar induction of pulsars and presented observational results. This paper further discusses the difference between the two braking mechanisms and analyses the results of a statistical study through observed data of apparent beamwidth's distributions and a geometrical method. The theory of magnetic dipole radiation of pulsars agrees with the observations. Unipolar induction as a braking mechanism is not consistent with the observations.

500