MEQALAC development at Brookhaven

International Nuclear Information System (INIS)

Gammel, G.; Brodowski, J.; Keane, J.; Maschke, A.; Meier, E.; Mobley, R.; Sanders, R.

1981-01-01

A novel method of transporting and accelerating high brightness ion beams, called MEQALAC, has been developed at Brookhaven. The concept and its motivation will be described first, with reference to other sources for detail, and then the performance of two operating MEQALAC's will be presented

Clinical trials of boron neutron capture therapy [in humans] [at Beth Israel Deaconess Medical Center][at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Wallace, Christine

2001-01-01

Assessment of research records of Boron Neutron Capture Therapy was conducted at Brookhaven National Laboratory and Beth Israel Deaconess Medical Center using the Code of Federal Regulations, FDA Regulations and Good Clinical Practice Guidelines. Clinical data were collected FR-om subjects' research charts, and differences in conduct of studies at both centers were examined. Records maintained at Brookhaven National Laboratory were not in compliance with regulatory standards. Beth Israel's records followed federal regulations. Deficiencies discovered at both sites are discussed in the reports

BROOKHAVEN: Booster commissioned

Energy Technology Data Exchange (ETDEWEB)

Bleser, Ed

1992-03-15

The construction and first commissioning phase of the Booster synchrotron to inject into Brookhaven's veteran Alternating Gradient Synchrotron (AGS) were completed last year. Scheduled to come into operation this year, the new Booster will extend the research capabilities AGS, and with its ability to accelerate partially stripped heavy ions will play an essential role in the chain of accelerators serving the Relativistic Heavy Ion Collider (RHIC)

BROOKHAVEN: High energy gold

International Nuclear Information System (INIS)

Bleser, Ed

1992-01-01

On April 24, Brookhaven's Alternating Gradient Synchrotron (AGS) started to deliver gold ions at 11.4 GeV per nucleon (2,000 GeV per ion) to experimenters who were delighted not only to receive the world's highest energy gold beam but also to receive it on schedule

BROOKHAVEN: Glueballs, hybrids and exotics

Energy Technology Data Exchange (ETDEWEB)

Chung, S. -U.

1988-12-15

A workshop at Brookhaven from August 29 to September 1 looked at the current status of hadron spectroscopy beyond the realm of states conventionally built up from quarks and discussed future experimental effort to explore such exotic states.

Brookhaven Highlights, January 1982-March 1983

Energy Technology Data Exchange (ETDEWEB)

Kuper, J.B.H.; Rustad, M.C. (eds.)

1983-01-01

Research at Brookhaven National Laboratory is summarized. Major headings are high energy physics, physics and chemistry, life sciences, applied energy science, support activities and administration. (GHT)

Brookhaven National Laboratory site environmental report for calendar year 1996

Energy Technology Data Exchange (ETDEWEB)

Schroeder, G.L.; Paquette, D.E.; Naidu, J.R.; Lee, R.J.; Briggs, S.L.K.

1998-01-01

This report documents the results of the Environmental Monitoring Program at Brookhaven National Laboratory and summarizes information about environmental compliance for 1996. To evaluate the effect of Brookhaven National Laboratory`s operations on the local environment, measurements of direct radiation, and of a variety of radionuclides and chemical compounds in the ambient air, soil, sewage effluent, surface water, groundwater, fauna, and vegetation were made at the Brookhaven National Laboratory site and at adjacent sites. The report also evaluates the Laboratory`s compliance with all applicable guides, standards, and limits for radiological and non-radiological emissions and effluents to the environment.

Brookhaven: RHIC magnets

International Nuclear Information System (INIS)

Heppelman, Steve

1990-01-01

Last year, Brookhaven's proposal for a Relativistic Heavy Ion Collider - RHIC - was scrutinized by the US Department of Energy and deemed to be ready for construction funding. The hope is that the money will be voted soon so that construction can get underway at the start of the new US financial year in October. The 3.8 kilometre RHIC tunnel was completed ten years ago for the doomed Isabelle/CBA proton collider project

Brookhaven highlights for fiscal year 1991, October 1, 1990--September 30, 1991

Energy Technology Data Exchange (ETDEWEB)

Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L.; Kuper, J.B.H.

1991-01-01

This report highlights Brookhaven National Laboratory's activities for fiscal year 1991. Topics from the four research divisions: Computing and Communications, Instrumentation, Reactors, and Safety and Environmental Protection are presented. The research programs at Brookhaven are diverse, as is reflected by the nine different scientific departments: Accelerator Development, Alternating Gradient Synchrotron, Applied Science, Biology, Chemistry, Medical, National Synchrotron Light Source, Nuclear Energy, and Physics. Administrative and managerial information about Brookhaven are also disclosed. (GHH)

Brookhaven highlights for fiscal year 1991, October 1, 1990--September 30, 1991

Energy Technology Data Exchange (ETDEWEB)

Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L.; Kuper, J.B.H.

1991-12-31

This report highlights Brookhaven National Laboratory`s activities for fiscal year 1991. Topics from the four research divisions: Computing and Communications, Instrumentation, Reactors, and Safety and Environmental Protection are presented. The research programs at Brookhaven are diverse, as is reflected by the nine different scientific departments: Accelerator Development, Alternating Gradient Synchrotron, Applied Science, Biology, Chemistry, Medical, National Synchrotron Light Source, Nuclear Energy, and Physics. Administrative and managerial information about Brookhaven are also disclosed. (GHH)

Brookhaven highlights for fiscal year 1991, October 1, 1990--September 30, 1991

International Nuclear Information System (INIS)

Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L.; Kuper, J.B.H.

1991-01-01

This report highlights Brookhaven National Laboratory's activities for fiscal year 1991. Topics from the four research divisions: Computing and Communications, Instrumentation, Reactors, and Safety and Environmental Protection are presented. The research programs at Brookhaven are diverse, as is reflected by the nine different scientific departments: Accelerator Development, Alternating Gradient Synchrotron, Applied Science, Biology, Chemistry, Medical, National Synchrotron Light Source, Nuclear Energy, and Physics. Administrative and managerial information about Brookhaven are also disclosed

Brookhaven at 40 - looking forward as well as back

International Nuclear Information System (INIS)

Anon.

1987-01-01

In 1947, the famous Camp Upton Army Base on New York's Long Island switched to a new career as Brookhaven National Laboratory. The reputation the Laboratory has established as a world-class research centre and its continued attraction for scientists looking for exciting possibilities were highlighted on 9-11 September at a symposium and celebration marking forty years of Brookhaven and its parent organization, AUI (Associated Universities Inc)

Brookhaven leak reactor to close

CERN Multimedia

MacIlwain, C

1999-01-01

The DOE has announced that the High Flux Beam Reactor at Brookhaven is to close for good. Though the news was not unexpected researchers were angry the decision had been taken before the review to assess the impact of reopening the reactor had been concluded (1 page).

MWPC data acquisition in the Brookhaven FASTBUS

International Nuclear Information System (INIS)

Black, J.K.; Blatt, S.R.; Campbell, M.C.

1983-01-01

For Brookhaven AGS Experiment No. 749, a data acquisition system to accommodate 12, 256 wire multiwire proportional chambers (MWPCs) has been built in the context of the Brookhaven FASTBUS. Information about wires hit or continuous clusters of wires hit is encoded as the centroids of the clusters and number of wires in those clusters. The encoded information is stored in a stack memory in a FASTBUS module where it can be accessed by a FASTBUS Master. Encoding time is less than 4 microseconds. Also, information (in the form of front panel outputs) as to the nature of the data is available in less than 200 nanoseconds

Barrier Cavities in the Brookhaven AGS

International Nuclear Information System (INIS)

Blaskiewicz, M.; Brennan, J. M.; Roser, T.; Smith, K.; Spitz, R.; Zaltsman, A.; Fujieda, M.; Iwashita, Y.; Noda, A.; Yoshii, M.; Mori, Y.; Ohmori, C.; Sato, Y.

1999-01-01

In collaboration with KEK two barrier cavities, each generating 40 kV per turn have been installed in the Brookhaven AGS. Machine studies are described and their implications for high intensity operations are discussed

Upgrade of the controls for the Brookhaven linac

International Nuclear Information System (INIS)

Buxton, W.E.

1995-01-01

The control of the magnets, rf system, and other components at the Brookhaven Linac uses a system that was developed at Brookhaven in the late 1960's. This system will be retired in the summer of 1995. The Linac controls are being upgraded using modem VME-based hardware compatible with RHIC generation controls, and an existing serial field bus. The timing for the Linac will also be upgraded and will use components developed for RHIC. The controls in general, the timing for the Linac, and the modules developed will be described

TRISTAN-II at Brookhaven

International Nuclear Information System (INIS)

Chrien, R.E.; Stelts, M.L.; Manzella, V.; Gill, R.; Wohn, F.; Hill, J.C.

1979-01-01

The mass separator TRISTAN has been moved to Brookhaven HFBR. A flux of up to 10 11 neutrons/cm 2 /sec will be available on target, and improvements in the ion source and beam optics have been made. A computer system with a CAMAC interface allows data collection from eight independent sources, while a PDP-11/34 computer is available for extensive off-line analysis

Brookhaven: Ready for RHIC

International Nuclear Information System (INIS)

Ludlam, Tom

1990-01-01

With its RHIC - Relativistic Heavy Ion Collider - project now part of the budget proposed by US President Bush for fiscal year 1991, Brookhaven is about to start construction of a unique kind of high energy collider. At a time when accelerators handling particles - electrons, protons and their antimatter counterparts - are boosting beam energies for microscopes to probe evershorter distances, RHIC is envisioned as a great pressure-cooker for strongly interacting matter

Brookhaven: Ready for RHIC

Energy Technology Data Exchange (ETDEWEB)

Ludlam, Tom

1990-04-15

With its RHIC - Relativistic Heavy Ion Collider - project now part of the budget proposed by US President Bush for fiscal year 1991, Brookhaven is about to start construction of a unique kind of high energy collider. At a time when accelerators handling particles - electrons, protons and their antimatter counterparts - are boosting beam energies for microscopes to probe evershorter distances, RHIC is envisioned as a great pressure-cooker for strongly interacting matter.

Brookhaven highlights, October 1979-September 1980

International Nuclear Information System (INIS)

1980-01-01

Highlights are given for the research areas of the Brookhaven National Laboratory. These areas include high energy physics, physics and chemistry, life sciences, applied energy science (energy and environment, and nuclear energy), and support activities (including mathematics, instrumentation, reactors, and safety)

BROOKHAVEN: Spin rotator to boost polarization

International Nuclear Information System (INIS)

Anon.

1991-01-01

The Alternating Gradient Synchrotron (AGS) at Brookhaven holds the world record energy for spin polarized proton beams at 22 GeV. However this required a complicated two-week commissioning effort to overcome 39 imperfection depolarizing resonances and six intrinsic depolarizing resonances

Brookhaven highlights, October 1979-September 1980

Energy Technology Data Exchange (ETDEWEB)

1980-01-01

Highlights are given for the research areas of the Brookhaven National Laboratory. These areas include high energy physics, physics and chemistry, life sciences, applied energy science (energy and environment, and nuclear energy), and support activities (including mathematics, instrumentation, reactors, and safety). (GHT)

The Brookhaven Accelerator Test Facility

International Nuclear Information System (INIS)

Batchelor, K.; Ben-Zvi, I.; Fernow, R.C.; Fischer, J.; Fisher, A.S.; Gallardo, J.; Jialin, Xie; Kirk, H.G.; Parsa, Z.; Palmer, R.B.; Rao, T.; Rogers, J.; Sheehan, J.; Tsang, T.Y.F.; Ulc, S.; Van Steenbergen, A.; Woodle, M.; Zhang, R.S.; McDonald, K.T.; Russell, D.P.; Jiang, Z.Y.; Pellegrini, C.; Wang, X.J.

1990-01-01

The Accelerator Test Facility (ATF), presently under construction at Brookhaven National laboratory, is described. It consists of a 50-MeV electron beam synchronizable to a high-peak power CO 2 laser. The interaction of electrons with the laser field will be probed, with some emphasis on exploring laser-based acceleration techniques. 5 refs., 2 figs

BROOKHAVEN: Japanese collaboration

International Nuclear Information System (INIS)

Thieberger, Peter

1995-01-01

Full text: The Japanese RIKEN Laboratory is contributing $20 million to help construct the RHIC Relativistic Heavy Ion Collider now being built at Brookhaven and due to be completed in 1999. In return, RIKEN will participate in research at RHIC. RHIC is being built to collide beams of heavy ions at energies of about 100 GeV per nucleon to explore hot and dense states of nuclear matter, with the ultimate aim of finding the quark-gluon plasma, the medium which existed in the fiery aftermath of the Big Bang before subsequently 'freezing' into nucleons. However another long-time Brookhaven speciality is handling beams of polarized (spin-oriented) protons in the 30 GeV AGS Alternating Gradient Synchrotron, which will act as the injector for RHIC. With the involvement of RIKEN, the RHIC programme now expands to cover polarized protons. Half of the RIKEN support will be used to build and install the special hardware needed to handle the polarized beams in RHIC. This includes 'Siberian Snakes' to negotiate depolarizing resonances which would otherwise mar beam acceleration (September 1994, page 27). The remaining RIKEN funding will go towards additional equipment for the PHENIX detector (May 1992, page 10) to enable it to cover spin physics. This equipment includes a second muon arm, with a magnet and tracking chamber. A multidisciplinary laboratory, RIKEN - Rikagaku Kenkyusho, or the Institute of Physical and Chemical Research - near Tokyo is currently the scene of construction of an 8 GeV synchrotron X-ray source

New Brookhaven chief seeks cross-cutting research

CERN Multimedia

Jones, D

2003-01-01

Brookhaven National Laboratory will pursue opportunities for promoting commercial development of energy systems and other technologies while focusing on the lab's primary mission of basic science research, according to the incoming BNL director, Praveen Chaudhari (1 page).

Brookhaven National Laboratory site environmental report for calendar year 1995

Energy Technology Data Exchange (ETDEWEB)

Naidu, J.R.; Paquette, D.E.; Schroeder, G.L. [eds.] [and others

1996-12-01

This report documents the results of the Environmental Monitoring Program at Brookhaven National Laboratory and summarizes information about environmental compliance for 1995. To evaluate the effect of Brookhaven National Laboratory`s operations on the local environment, measurements of direct radiation, and of a variety of radionuclides and chemical compounds in the ambient air, soil, sewage effluent, surface water, groundwater, fauna, and vegetation were made at the Brookhaven National Laboratory site and at adjacent sites. The report also evaluates the Laboratory`s compliance with all applicable guides, standards, and limits for radiological and nonradiological emissions and effluents to the environment. Areas of known contamination are subject to Remedial Investigation/Feasibility Studies under the Inter Agency Agreement established by the Department of Energy, Environmental Protection Agency and the New York Department of Environmental Conservation. Except for identified areas of soil and groundwater contamination, the environmental monitoring data has continued to demonstrate that compliance was achieved with the applicable environmental laws and regulations governing emission and discharge of materials to the environment. Also, the data show that the environmental impacts at Brookhaven National Laboratory are minimal and pose no threat to the public nor to the environment. This report meets the requirements of Department of Energy Orders 5484.1, Environmental Protection, Safety, and Health Protection Information reporting requirements and 5400.1, General Environmental Protection Programs.

Brookhaven highlights, October 1, 1989--September 30, 1990

Energy Technology Data Exchange (ETDEWEB)

Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L.; Kuper, J.B.H. (eds.)

1990-01-01

This report discusses research being conducted at Brookhaven National Laboratory. Highlights from all the department are illustrated. The main topics are on accelerator development and applications. (LSP)

Applied programs at Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

1991-09-01

This document overviews the areas of current research at Brookhaven National Laboratory. Technology transfer and the user facilities are discussed. Current topics are presented in the areas of applied physics, chemical science, material science, energy efficiency and conservation, environmental health and mathematics, biosystems and process science, oceanography, and nuclear energy. (GHH)

Practical considerations for effective microendoscopy

Science.gov (United States)

Papaioannou, Thanassis; Papazoglou, Theodore G.; Daykhovsky, Leon; Gershman, Alex; Segalowitz, Jacob; Reznik, G.; Beeder, Clain; Chandra, Mudjianto; Grundfest, Warren S.

1991-07-01

This paper reports on the application of angioscopic technology to the endoscopy of previously inaccessible body cavities. Necessary instruments including endoscopes, light sources, cameras, video recorders, monitors, and other accessories are described. Practical considerations for effective instrumentation are discussed. An overview of our clinical microendoscopic applications in more than 630 patients is presented.

A woman like you: Women scientists and engineers at Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Benkovitz, Carmen; Bernholc, Nicole; Cohen, Anita; Eng, Susan; Enriquez-Leder, Rosario; Franz, Barbara; Gorden, Patricia; Hanson, Louise; Lamble, Geraldine; Martin, Harriet; Mastrangelo, Iris; McLane, Victoria; Villela, Maria-Alicia; Vivirito, Katherine; Woodhead, Avril

1991-01-01

This publication by the women in Science and Engineering introduces career possibilities in science and engineering. It introduces what work and home life are like for women who have already entered these fields. Women at Brookhaven National Laboratory work in a variety of challenging research roles -- from biologist and environmental scientist to safety engineer, from patent lawyer to technician. Brookhaven National Laboratory is a multi-program laboratory which carries out basic and applied research in the physical, biomedical and environmental sciences and in selected energy technologies. The Laboratory is managed by Associated University, Inc., under contract with the US Department of Energy. Brookhaven and the other national laboratories, because of their enormous research resources, can play a critical role in a education and training of the workforce.

The Amtex DAMA Project: The Brookhaven contribution

Energy Technology Data Exchange (ETDEWEB)

Peskin, A.M.

1995-01-01

The Amtex Partnership organized in 1993 as a Technology Transfer Collaboration among members of the integrated textile industry, the DOE National Laboratories, a number of universities, and several research/education/technology transfer organizations (RETTs). Under the Amtex umbrella organization, a number of technology areas were defined and individual projects were launched addressing various aspects of improving the health and competitiveness of the American textile industry. The first and, to date, the largest of these has been the computer-based Demand Activated Manufacturing Architecture (DAMA) project. Brookhaven National Laboratory became involved in DAMA beginning in March of 1993 and remained an active participant through January of 1995. It was staffed almost exclusively with personnel of the Computing and Communications Division. This document summarizes the activities and accomplishments of the Brookhaven team in working with the larger collaboration. Detailed information about the Amtex Partnership, the DAMA Project, and specific BNL contributions are documented elsewhere.

The Brookhaven electron analogue, 1953--1957

Energy Technology Data Exchange (ETDEWEB)

Plotkin, M.

1991-12-18

The following topics are discussed on the Brookhaven electron analogue: L.J. Haworth and E.L. VanHorn letters; Original G.K. Green outline for report; General description; Parameter list; Mechanical Assembly; Alignment; Degaussing; Vacuum System; Injection System; The pulsed inflector; RF System; Ferrite Cavity; Pick-up electrodes and preamplifiers; Radio Frequency power amplifier; Lens supply; Controls and Power; and RF acceleration summary.

The Brookhaven electron analogue, 1953--1957

International Nuclear Information System (INIS)

Plotkin, M.

1991-01-01

The following topics are discussed on the Brookhaven electron analogue: L.J. Haworth and E.L. VanHorn letters; Original G.K. Green outline for report; General description; Parameter list; Mechanical Assembly; Alignment; Degaussing; Vacuum System; Injection System; The pulsed inflector; RF System; Ferrite Cavity; Pick-up electrodes and preamplifiers; Radio Frequency power amplifier; Lens supply; Controls and Power; and RF acceleration summary

BROOKHAVEN NATIONAL LABORATORY INSTITUTIONAL PLAN FY2003-2007.

Energy Technology Data Exchange (ETDEWEB)

NONE

2003-06-10

This document presents the vision for Brookhaven National Laboratory (BNL) for the next five years, and a roadmap for implementing that vision. Brookhaven is a multidisciplinary science-based laboratory operated for the U.S. Department of Energy (DOE), supported primarily by programs sponsored by the DOE's Office of Science. As the third-largest funding agency for science in the U.S., one of the DOE's goals is ''to advance basic research and the instruments of science that are the foundations for DOE's applied missions, a base for U.S. technology innovation, and a source of remarkable insights into our physical and biological world, and the nature of matter and energy'' (DOE Office of Science Strategic Plan, 2000 http://www.osti.gov/portfolio/science.htm). BNL shapes its vision according to this plan.

BROOKHAVEN: Booster boost

International Nuclear Information System (INIS)

Anon.

1993-01-01

After three months of intensive dedicated machine studies, Brookhaven's new Booster accelerated 5 x 10 13 protons over four cycles, about 85% of the design intensity. This was made possible by careful matching of Linac beam into the Booster and by extensive resonance stop band corrections implemented during Booster acceleration. The best single cycle injection into the AGS Alternating Gradient Synchrotron was 1.14 x 10 13 protons from the Booster. 1.05 x 10 13 protons were kept in the AGS, a 92% combined efficiency of extraction, transfer, and injection. The maximum injected 1994 shutdown period, enabling the 1994 physics run to make use of the full Booster intensity and go for the stated AGS objective of 4x10 13 protons per pulse

Protocols for BNCT of glioblastoma multiforme at Brookhaven: Practical considerations

Energy Technology Data Exchange (ETDEWEB)

Chanana, A.D.; Coderre, J.A.; Joel, D.D.; Slatkin, D.N.

1996-12-31

In this report we discuss some issues considered in selecting initial protocols for boron neutron capture therapy (BNCT) of human glioblastoma multiforme. First the tolerance of normal tissues, especially the brain, to the radiation field. Radiation doses limits were based on results with human and animal exposures. Estimates of tumor control doses were based on the results of single-fraction photon therapy and single fraction BNCT both in humans and experimental animals. Of the two boron compounds (BSH and BPA), BPA was chosen since a FDA-sanctioned protocol for distribution in humans was in effect at the time the first BNCT protocols were written and therapy studies in experimental animals had shown it to be more effective than BSH.

BROOKHAVEN NATIONAL LABORATORY SITE ENVIRONMENTAL REPORT FOR CALENDAR YEAR 1994.

Energy Technology Data Exchange (ETDEWEB)

NAIDU,J.R.; ROYCE,B.A.

1995-05-01

This report documents the results of the Environmental Monitoring Program at Brookhaven National Laboratory and presents summary information about environmental compliance for 1994. To evaluate the effect of Brookhaven National Laboratory's operations on the local environment, measurements of direct radiation, and a variety of radionuclides and chemical compounds in ambient air, soil, sewage effluent, surface water, groundwater, fauna and vegetation were made at the Brookhaven National Laboratory site and at sites adjacent to the Laboratory. Brookhaven National Laboratory's compliance with all applicable guides, standards, and limits for radiological and nonradiological emissions and effluents to the environment were evaluated. Among the permitted facilities, two instances of pH exceedances were observed at recharge basins, possibly related to rain-water run-off to these recharge basins. Also, the discharge from the Sewage Treatment Plant to the Peconic River exceeded. on ten occasions, one each for fecal coliform and 5-day Biochemical Oxygen Demand (avg.) and eight for ammonia nitrogen. The ammonia and Biochemical Oxygen Demand exceedances were attributed to the cold winter and the routine cultivation of the sand filter beds which resulted in the hydraulic overloading of the filter beds and the possible destruction of nitrifying bacteria. The on-set of warm weather and increased aeration of the filter beds via cultivation helped to alleviate this condition. The discharge of fecal coliform may also be linked to this occurrence, in that the increase in fecal coliform coincided with the increased cultivation of the sand filter beds. The environmental monitoring data has identified site-specific contamination of groundwater and soil. These areas are subject to Remedial Investigation/Feasibility Studies under the Inter Agency Agreement. Except for the above, the environmental monitoring data has continued to demonstrate that compliance was achieved with

Brookhaven highlights

International Nuclear Information System (INIS)

Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L.

1992-01-01

This publication provides a broad overview of the research programs and efforts being conducted, built, designed, and planned at Brookhaven National Laboratory. This work covers a broad range of scientific disciplines. Major facilities include the Alternating Gradient Synchrotron (AGS), with its newly completed booster, the National Synchrotron Light Source (NSLS), the High Flux Beam Reactor (HFBR), and the RHIC, which is under construction. Departments within the laboratory include the AGS department, accelerator development, physics, chemistry, biology, NSLS, medical, nuclear energy, and interdepartmental research efforts. Research ranges from the pure sciences, in nuclear physics and high energy physics as one example, to environmental work in applied science to study climatic effects, from efforts in biology which are a component of the human genome project to the study, production, and characterization of new materials. The paper provides an overview of the laboratory operations during 1992, including staffing, research, honors, funding, and general laboratory plans for the future

Brookhaven highlights

Energy Technology Data Exchange (ETDEWEB)

Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L. (eds.)

1992-01-01

This publication provides a broad overview of the research programs and efforts being conducted, built, designed, and planned at Brookhaven National Laboratory. This work covers a broad range of scientific disciplines. Major facilities include the Alternating Gradient Synchrotron (AGS), with its newly completed booster, the National Synchrotron Light Source (NSLS), the High Flux Beam Reactor (HFBR), and the RHIC, which is under construction. Departments within the laboratory include the AGS department, accelerator development, physics, chemistry, biology, NSLS, medical, nuclear energy, and interdepartmental research efforts. Research ranges from the pure sciences, in nuclear physics and high energy physics as one example, to environmental work in applied science to study climatic effects, from efforts in biology which are a component of the human genome project to the study, production, and characterization of new materials. The paper provides an overview of the laboratory operations during 1992, including staffing, research, honors, funding, and general laboratory plans for the future.

Video Games - Did They Begin at Brookhaven

Science.gov (United States)

dropdown arrow Site Map A-Z Index Menu Synopsis Video Games – Did They Begin at Brookhaven? Additional Web program led to the pioneering development of video games. William Higinbotham William Higinbotham First Pong, now Space Invaders, next Star Castle – video games have mesmerized children of at all ages

Proposed Brookhaven accelerator-based neutron generator

International Nuclear Information System (INIS)

Grand, P.; Batchelor, K.; Chasman, R.; Rheaume, R.

1976-01-01

The d-Li Neutron Source concept, which includes a high-current dueteron linac, is an outgrowth of attempts made to use the BNL, 200-MeV proton linac BLIP facility to do radiation damage studies. It included a 100 mA, 30-MeV deuteron linear accelerator and a fast-flowing liquid lithium jet as the target. The latest design is not very different, except that the current is now 200 mA and the linac energy has been raised to 35 MeV. Both parameters, were changed to optimize the effectiveness of the facility with respect to flux, experimental volume and match to 14 MeV neutron-radiation-damage effects. The proposed Brookhaven Accelerator-based Neutron Generator is described with particular emphasis on the linear accelerator. The proposed facility is a practical and efficient way of producing the intense, high energy neutron beams needed for CTR material studies. The accelerator and liquid-metal technologies are well proven, state-of-the-art technologies. The fact that no new technology is required guarantees the possibility of meeting construction schedules, and more importantly, guarantees a high level of operational reliability

Accelerator timing at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Oerter, B.; Conkling, C.R.

1995-01-01

Accelerator timing at Brookhaven National Laboratory has evolved from multiple coaxial cables transmitting individual pulses in the original Alternating Gradient Synchrotron (AGS) design, to serial coded transmission as the AGS Booster was added. With the implementation of this technology, the Super Cycle Generator (SCG) which synchronizes the AGS, Booster, LINAC, and Tandem accelerators was introduced. This paper will describe the timing system being developed for the Relativistic Heavy Ion Collider (RHIC)

From heavy ions to light sources at Brookhaven

International Nuclear Information System (INIS)

Anon.

1985-01-01

The Brookhaven National Laboratory, recovered from the debacle of the cancelled CBA proton-proton collider project, is now more than busy with an excellent physics programme at the 33 GeV Alternating Gradient Synchrotron and with solid projects for the years to come. (orig.).

Vertical velocity variances and Reynold stresses at Brookhaven

DEFF Research Database (Denmark)

Busch, Niels E.; Brown, R.M.; Frizzola, J.A.

1970-01-01

Results of wind tunnel tests of the Brookhaven annular bivane are presented. The energy transfer functions describing the instrument response and the numerical filter employed in the data reduction process have been used to obtain corrected values of the normalized variance of the vertical wind v...

Constraining Anomaly Mediated Supersymmetry Breaking Framework via Ongoing Muon g-2 Experiment at Brookhaven

CERN Document Server

Chattopadhyay, U; Roy, S; PH; Chattopadhyay, Utpal; Ghosh, Dilip Kumar; Roy, Sourov

2000-01-01

The ongoing high precision E821 Brookhaven National Laboratory experiment on muon g-2 is promising to probe a theory involving supersymmetry. We have studied the constraints on minimal Anomaly Mediated Supersymmetry Breaking (AMSB) model using the current data of muon g-2 from Brookhaven. A scenario of seeing no deviation from the Standard Model is also considered, within $2\\sigma$ limit of the combined error from the Standard Model result and the Brookhaven predicted uncertainty level. The resulting constraint is found to be complementary to what one obtains from $b \\to s+ \\gamma$ bounds within the AMSB scenario, since only a definite sign of $\\mu$ is effectively probed via $b \\to s+ \\gamma$. A few relevant generic features of the model are also described for disallowed regions of the parameter space.

Brookhaven National Laboratory moves to the fast lane

CERN Multimedia

2006-01-01

"The U.S. Department of Energy's energy sciences network (ESnet) continues to roll out its next-generation architecture on schedule with the March 14 completion of the Long Island Metropolitan Area Network, connecting Brookhaven National Laboratory (BNL) to the ESnet point of presente (PO) 60 miles away in New York City." (1 page)

Database activities at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Trahern, C.G.

1995-01-01

Brookhaven National Laboratory is a multi-disciplinary lab in the DOE system of research laboratories. Database activities are correspondingly diverse within the restrictions imposed by the dominant relational database paradigm. The authors discuss related activities and tools used in RHIC and in the other major projects at BNL. The others are the Protein Data Bank being maintained by the Chemistry department, and a Geographical Information System (GIS)--a Superfund sponsored environmental monitoring project under development in the Office of Environmental Restoration

A woman like you: Women scientists and engineers at Brookhaven National Laboratory. Careers in action

Energy Technology Data Exchange (ETDEWEB)

1991-12-31

This publication by the women in Science and Engineering introduces career possibilities in science and engineering. It introduces what work and home life are like for women who have already entered these fields. Women at Brookhaven National Laboratory work in a variety of challenging research roles -- from biologist and environmental scientist to safety engineer, from patent lawyer to technician. Brookhaven National Laboratory is a multi-program laboratory which carries out basic and applied research in the physical, biomedical and environmental sciences and in selected energy technologies. The Laboratory is managed by Associated University, Inc., under contract with the US Department of Energy. Brookhaven and the other national laboratories, because of their enormous research resources, can play a critical role in a education and training of the workforce.

Searching for the H dibaryon at Brookhaven

Energy Technology Data Exchange (ETDEWEB)

Schwartz, A.J. [Princeton Univ., NJ (United States)

1994-12-01

This paper reviews the status of current experiments at Brookhaven, searching for the six-quark H dibaryon postulated by R. Jaffe in 1977. Two experiments, E813 and E888, have recently completed running and two new experiments, E836 and E885, are approved to run. The data recorded so far is under analysis and should have good sensitivity to both short-lived and long-lived Hs.

Description of the intense, low energy, monoenergetic positron beam at Brookhaven

International Nuclear Information System (INIS)

Lynn, K.G.; Mills, A.P. Jr.; Roellig, L.O.; Weber, M.

1985-01-01

An intense (4 x 10 7 s -1 ), low energy (approx. =1.0 eV), monoenergetic (ΔE approx. = 75 MeV) beam of positrons has been built at the Brookhaven National Laboratory. This flux is more than 10 times greater than any existing beam from radioactive sources. Plans are underway to increase further the flux by more than an order of magnitude. The intense low energy positron beam is made by utilizing the High Flux Beam Reactor at Brookhaven to produce the isotope 64 Cu with an activity of 40 curies of positrons. Source moderation techniques are utilized to produce the low energy positron beam from the high energy positrons emitted from 64 Cu. 31 refs., 7 figs

Small Modular Reactors (468th Brookhaven Lecture)

International Nuclear Information System (INIS)

Bari, Robert

2011-01-01

With good reason, much more media attention has focused on nuclear power plants than solar farms, wind farms, or hydroelectric plants during the past month and a half. But as nations around the world demand more energy to power everything from cell phone batteries to drinking water pumps to foundries, nuclear plants are the only non-greenhouse-gas producing option that can be built to operate almost anywhere, and can continue to generate power during droughts, after the sun sets, and when winds die down. To supply this demand for power, designers around the world are competing to develop more affordable nuclear reactors of the future: small modular reactors. Brookhaven Lab is working with DOE to ensure that these reactors are designed to be safe for workers, members of surrounding communities, and the environment and to ensure that the radioactive materials and technology will only be used for peaceful purposes, not weapons. In his talk, Bari will discuss the advantages and challenges of small modular reactors and what drives both international and domestic interest in them. He will also explain how Brookhaven Lab and DOE are working to address the challenges and provide a framework for small modular reactors to be commercialized.

The Brookhaven National Laboratory Accelerator Test Facility

International Nuclear Information System (INIS)

Batchelor, K.

1992-01-01

The Brookhaven National Laboratory Accelerator Test Facility comprises a 50 MeV traveling wave electron linear accelerator utilizing a high gradient, photo-excited, raidofrequency electron gun as an injector and an experimental area for study of new acceleration methods or advanced radiation sources using free electron lasers. Early operation of the linear accelerator system including calculated and measured beam parameters are presented together with the experimental program for accelerator physics and free electron laser studies

Relay testing at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Bandyopadhyay, K.; Hofmayer, C.

1989-01-01

Brookhaven National Laboratory (BNL) is conducting a seismic test program on relays. The purpose of the test program is to investigate the influence of various designs, electrical and vibration parameters on the seismic capacity levels. The first series of testing has been completed and performed at Wyle Laboratories. The major part of the test program consisted of single axis, single frequency sine dwell tests. Random multiaxis, multifrequency tests were also performed. Highlights of the test results as well as a description of the testing methods are presented in this paper. 10 figs

Brookhaven Lab and Argonne Lab scientists invent a plasma valve

CERN Multimedia

2003-01-01

Scientists from Brookhaven National Laboratory and Argonne National Laboratory have received U.S. patent number 6,528,948 for a device that shuts off airflow into a vacuum about one million times faster than mechanical valves or shutters that are currently in use (1 page).

Study of ν interactions at Brookhaven using counter techniques

International Nuclear Information System (INIS)

Williams, H.H.

1977-01-01

A review is presented of neutrino elastic scattering, νp → νp and anti νp → anti νp, as observed by the Harvard-Pennsylvania-Wisconsin (HPW) and Columbia-Illinois-Rockefeller (CIR) experiments at Brookhaven National Laboratory. Results from the CIR experiment on (anti) νN → (anti) νNπsup(o) are also discussed. (orig.) [de

The Brookhaven Accelerator Test Facility

International Nuclear Information System (INIS)

Batchelor, K.; Chou, T.S.; Fernow, R.C.

1988-01-01

The Brookhaven Accelerator Test Facility (ATF) will consist of a 50--100 MeV/c electron linac and a 100 GW CO 2 laser system. A high brightness RF-gun operating at 2856 MHz is to be used as the injector into the linac. The RF-gun contains a Nd:Yag-laser-driven photocathode capable of producing a stream of six ps electron pulses separated by 12.5 ns. The maximum charge in a micropulse will be one nano-Coulomb. The CO 2 laser pulse length will be a few picoseconds and will be synchronized with the electron pulse. The first experimental beam is expected in Fall 89. The design electron beam parameters are given and possible initial experiments are discussed. 9 refs., 1 fig., 3 tabs

Activities of the cross-section compilation and evaluation centers at the Brookhaven National Laboratory

International Nuclear Information System (INIS)

Chernick, J.

1967-01-01

The growth of the compilation and evaluation efforts at the Brookhaven National Laboratory are reviewed. The current work of the Sigma Center is discussed, including the status of the publication of supplements to BNL-325 and the current state of the SCISRS-I tape. Future needs for BNL-325 type publications and SCISRS-II cross-section tapes are outlined. The history of the Cross-Section Evaluation Center at the Brookhaven National Laboratory is similarly reviewed. The status of current work is discussed, including the growth of the ENDF/A tape. The status of US efforts to produce a cross-section tape (ENDF7B) at an early date to satisfy the needs of US reactor designers is discussed. The continued importance of integral experiments and their accurate analysis to provide checks of the cross-section tapes is pointed out. The role of the Brookhaven National Laboratory in collaboration on an international basis is reviewed, including its current relationship to the ENEA Neutron Data Compilation Centre, the International Atomic Energy Agency and other nuclear centres. (author)

Brookhaven National Laboratory's Accelerator Test Facility: research highlights and plans

Science.gov (United States)

Pogorelsky, I. V.; Ben-Zvi, I.

2014-08-01

The Accelerator Test Facility (ATF) at Brookhaven National Laboratory has served as a user facility for accelerator science for over a quarter of a century. In fulfilling this mission, the ATF offers the unique combination of a high-brightness 80 MeV electron beam that is synchronized to a 1 TW picosecond CO2 laser. We unveil herein our plan to considerably expand the ATF's floor space with an upgrade of the electron beam's energy to 300 MeV and the CO2 laser's peak power to 100 TW. This upgrade will propel the ATF even further to the forefront of research on advanced accelerators and radiation sources, supporting the most innovative ideas in this field. We discuss emerging opportunities for scientific breakthroughs, including the following: plasma wakefield acceleration studies in research directions already active at the ATF; laser wakefield acceleration (LWFA), where the longer laser wavelengths are expected to engender a proportional increase in the beam's charge while our linac will assure, for the first time, the opportunity to undertake detailed studies of seeding and staging of the LWFA; proton acceleration to the 100-200 MeV level, which is essential for medical applications; and others.

The High Flux Beam Reactor at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Shapiro, S.M.

1994-01-01

Brookhaven National Laboratory's High Flux Beam Reactor (HFBR) was built because of the need of the scientist to always want 'more'. In the mid-50's the Brookhaven Graphite reactor was churning away producing a number of new results when the current generation of scientists, led by Donald Hughes, realized the need for a high flux reactor and started down the political, scientific and engineering path that led to the BFBR. The effort was joined by a number of engineers and scientists among them, Chemick, Hastings, Kouts, and Hendrie, who came up with the novel design of the HFBR. The two innovative features that have been incorporated in nearly all other research reactors built since are: (i) an under moderated core arrangement which enables the thermal flux to peak outside the core region where beam tubes can be placed, and (ii) beam tubes that are tangential to the core which decrease the fast neutron background without affecting the thermal beam intensity. Construction began in the fall of 1961 and four years later, at a cost of $12 Million, criticality was achieved on Halloween Night, 1965. Thus began 30 years of scientific accomplishments

Brookhaven National Laboratory Institutional Plan FY2001--FY2005

Energy Technology Data Exchange (ETDEWEB)

Davis, S.

2000-10-01

Brookhaven National Laboratory is a multidisciplinary laboratory in the Department of Energy National Laboratory system and plays a lead role in the DOE Science and Technology mission. The Laboratory also contributes to the DOE missions in Energy Resources, Environmental Quality, and National Security. Brookhaven strives for excellence in its science research and in facility operations and manages its activities with particular sensitivity to environmental and community issues. The Laboratory's programs are aligned continuously with the goals and objectives of the DOE through an Integrated Planning Process. This Institutional Plan summarizes the portfolio of research and capabilities that will assure success in the Laboratory's mission in the future. It also sets forth BNL strategies for our programs and for management of the Laboratory. The Department of Energy national laboratory system provides extensive capabilities in both world class research expertise and unique facilities that cannot exist without federal support. Through these national resources, which are available to researchers from industry, universities, other government agencies and other nations, the Department advances the energy, environmental, economic and national security well being of the US, provides for the international advancement of science, and educates future scientists and engineers.

Technical considerations and problems associated with long-term storage of low-level waste

International Nuclear Information System (INIS)

Siskind, B.

1991-01-01

If a state or regional compact does not have adequate disposal capacity for low-level radioactive waste (LLRW), then extended storage of certain LLRW may be necessary. The Nuclear Regulatory Commission (NRC) contracted with Brookhaven National Laboratory (BNL) several years ago (1984--86) to address the technical issues of extended storage. The dual objectives of this study were (1) to provide practical technical assessments for NRC to consider in evaluating specific proposals for extended storage and (2) to help ensure adequate consideration by NRC, Agreement States, and licensees of potential problems that may arise from existing or proposed extended storage practices. In this summary of that study, the circumstances under which extended storage of LLRW would most likely result in problems during or after the extended storage period are considered and possible mitigative measures to minimize these problems are discussed. These potential problem areas include: (1) the degradation of carbon steel and polyethylene containers during storage and the subsequent need for repackaging (resulting in increased occupational exposure), (2) the generation of hazardous gases during storage, and (3) biodegradative processes in LLRW

Summary of some work on high temperature superconductors at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Strongin, M.

1987-01-01

A summary is presented of recent high T/sub c/ superconductivity work by the Brookhaven staff. Significant work done by outside users on the major facilities is not discussed here. Theoretical work on mechanisms of superconductivity, is discussed separately elsewhere in this proceedings. The experimental work can be divided into two major categories; scattering and spectroscopy experiments at the Brookhaven facilities, and measurements of the macroscopic electrical and magnetic properties of the superconductors, as well as an additional contribution on sample preparation. An example of the complimentary nature of these techniques is shown for the case of penetration depth measurements, where the value of λ obtained using mu mesons as a microscopic probe of the internal fields is different than that obtained inductively. This difference leads to some insight into the inter-granular coupling

The Brookhaven Accelerator Test Facility

International Nuclear Information System (INIS)

Batchelor, K.; Chou, T.S.; Fernow, R.C.; Fischer, J.; Gallardo, J.; Kirk, H.G.; Koul, R.; Palmer, R.B.; Pellegrini, C.; Sheehan, J.; Srinivasan-Rao, T.; Ulc, S.; Woodle, M.; Bigio, I.; Kurnit, N.; McDonald, K.T.

1989-01-01

The Brookhaven Accelerator Test Facility ATF will consist of a 50-100 MeV/c electron linac and a 100 GW CO 2 laser system. A high brightness RF-gun operating at 2,856 MHz is to be used as the injector into the linac. The RF-gun contains a Nd:Yag-laser-driven photocathode capable of producing a stream of six ps electron pulses separated by 12.5 ns. The maximum charge in a micropulse will be one nano-Coulomb. The CO 2 laser pulse length will be a few picoseconds and will be synchronized with the electron pulse. The first experimental beam is expected in Fall 89. The design electron beam parameters are given and possible initial experiments are discussed. 9 refs., 1 fig., 3 tabs

Brookhaven National Laboratory's multiparticle spectrometer drift chamber system

International Nuclear Information System (INIS)

Etkin, A.; Kramer, M.A.

1979-01-01

A system of drift chambers is being built to replace the present spark chambers in the Brookhaven National Laboratory's Multiparticle Spectrometer. This system will handle a beam of approx. 3 million particles per second and have a resolution of 200 μm. A summary of the status of the chambers and the custom integrated circuits is presented. The data acquisition system is described. Prototype chambers have been built and tested with results that are consistent with the expected chamber properties

The Brookhaven ATF low-emittance beam line

International Nuclear Information System (INIS)

Wang, X.J.; Kirk, H.G.

1991-01-01

One component of the experimental program at the Brookhaven Accelerator Test Facility (ATF) consists of a class of experiments which will study the acceleration of electrons through micron-size structures which are exposed in coincidence to a 100 GW CO 2 laser beam. These experiments require the development and control of an electron beam with geometric emittances on the order of 10 -10 m-rad and intensities on the order of 10 6 electrons. In this paper, the authors describe the strategies for producing such beams and the effects of higher-order aberrations. Particle tracking results are presented for the final-focus system

Polarized proton acceleration at the Brookhaven AGS

International Nuclear Information System (INIS)

Ahrens, L.A.

1986-01-01

At the conclusion of polarized proton commissioning in February 1986, protons with an average polarization of 45%, momentum of 21.7 GeV/c, and intensity of 2 x 10 10 protons per pulse, were extracted to an external polarimeter at the Brookhaven AGS. In order to maintain this polarization, five intrinsic and nearly forty imperfection depolarizing resonances had to be corrected. An apparent interaction between imperfection and intrinsic resonances occurring at very nearly the same energy was observed and the correction of imperfection resonances using ''beat'' magnetic harmonics discovered in the previous AGS commissioning run was further confirmed

Neutron detector development at Brookhaven

International Nuclear Information System (INIS)

Yu, B.; Harder, J.A.; Mead, J.A.; Radeka, V.; Schaknowski, N.A.; Smith, G.C.

2003-01-01

Two-dimensional thermal neutron detectors have been the subject of research and development at Brookhaven for over 20 years. Based primarily on multi-wire chambers filled with a gas mixture containing 3 He, these detectors have been used in wide-ranging studies of molecular biology and material science samples. At each phase of development, experimenters have sought improvements in key parameters such as position resolution, counting rate, efficiency, solid-angle coverage and stability. A suite of detectors has been developed with sensitive areas ranging from 5x5 to 50x50 cm 2 . These devices incorporate low-noise-position readout and the best position resolution for thermal neutron gas detectors. Recent developments include a 1.5 mx20 cm detector containing multiple segments with continuously sensitive readout, and detectors with unity gain for ultra-high rate capability and long-term stability

A neutronic feasibility study for LEU conversion of the Brookhaven Medical Research Reactor (BMRR).

Energy Technology Data Exchange (ETDEWEB)

Hanan, N. A.

1998-01-14

A neutronic feasibility study for converting the Brookhaven Medical Research Reactor from HEU to LEU fuel was performed at Argonne National Laboratory in cooperation with Brookhaven National Laboratory. Two possible LEU cores were identified that would provide nearly the same neutron flux and spectrum as the present HEU core at irradiation facilities that are used for Boron Neutron Capture Therapy and for animal research. One core has 17 and the other has 18 LEU MTR-type fuel assemblies with uranium densities of 2.5g U/cm{sup 3} or less in the fuel meat. This LEU fuel is fully-qualified for routine use. Thermal hydraulics and safety analyses need to be performed to complete the feasibility study.

Data acquisition system for Experiment E866 at the Brookhaven AGS

International Nuclear Information System (INIS)

Ashktorab, K.; LeVine, M.J.; Scheetz, R.A.

1993-01-01

Experiment E866 consists of two spectrometers and related detectors for investigations of collisions of relativistic beams of Au ions with fixed targets at the Brookhaven AGS. The data acquisition system, consisting of 11 CPUs in a single VME crate, gathers data from 8 Camac crates and 6 Fastbus crates

The superconducting x-ray lithography source program at Brookhaven

Energy Technology Data Exchange (ETDEWEB)

Williams, G. P.; Heese, R. N.; Vignola, G.; Murphy, J. B.; Godel, J. B.; Hsieh, H.; Galayda, J.; Seifert, A.; Knotek, M. L.

1989-07-01

A compact electron storage ring with superconducting dipole magnets, is being developed at the National Synchrotron Light Source at Brookhaven. The parameters of the source have been optimized for its future use as an x-ray source for lithography. This first ring is a prototype which will be used to study the operating characteristics of machines of this type with particular attention being paid to low-energy injection and long beam lifetime.

Performance of the Brookhaven photocathode rf gun

International Nuclear Information System (INIS)

Batchelor, K.; Ben-Zvi, I.; Fernow, R.C.; Fischer, J.; Fisher, A.S.; Gallardo, J.; Ingold, G.; Kirk, H.G.; Leung, K.P.; Malone, R.; Pogorelsky, I.; Srinivasan-Rao, T.; Rogers, J.; Tsang, T.; Sheehan, J.; Ulc, S.; Woodle, M.; Xie, J.; Zhang, R.S.; Lin, L.Y.; McDonald, K.T.; Russell, D.P.; Hung, C.M.; Wang, X.J.

1991-01-01

The Brookhaven Accelerator Test Facility (ATF) uses a photocathode rf gun to provide a high-brightness electron beam intended for FEL and laser-acceleration experiments. The rf gun consists of 1 1/2 cells driven at 2856 MHz in π-mode with a maximum cathode field of 100 MV/m. To achieve long lifetimes, the photocathode development concentrates on robust metals such as copper, yttrium and samarium. We illuminate these cathodes with a 10-ps, frequency-quadrupled Nd:YAG laser. We describe the initial operation of the gun, including measurements of transverse and longitudinal emittance, quantum efficiencies, and peak current. The results are compared to models

The Brookhaven ATF low-emittance beam line

International Nuclear Information System (INIS)

Wang, X.J.

1991-01-01

One component of the experimental program at the Brookhaven Accelerator Test Facility (ATF) consists of a class of experiments which will study the acceleration of electrons through micron-size structures which are exposed in coincidence to a 100 GW CO 2 laser beam. These experiments require the development and control of an electron beam with geometric emittances on the order of 10 -10 m-rad and intensities on the order of 10 6 electrons. In this paper, we describe the strategies for producing such beams and the effects of high-order aberrations. Particle tracking results are presented for the final-focus system. 9 refs., 6 figs., 2 tabs

The Relativistic Heavy Ion Collider at Brookhaven

International Nuclear Information System (INIS)

Hahn, H.

1989-01-01

The conceptual design of a collider capable of accelerating and colliding heavy ions and to be constructed in the existing 3.8 km tunnel at Brookhaven has been developed. The collider has been designed to provide collisions of gold ions at six intersection points with a luminosity of about 2 x 10 26 cm -2 sec -1 at an energy per nucleon of 100 GeV in each beam. Collisions with different ion species, including protons, will be possible. The salient design features and the reasons for major design choices of the proposed machine are discussed in this paper. 28 refs., 2 figs., 1 tab

The neutrino horn 300 kiloampere pulsed power supply at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Sandberg, J.; Smith, G.A.; Carroll, A.S.

1987-01-01

A 300 Kiloampere pulsed power system used to energize the Brookhaven focusing neutrino horn is described. The constant current switching section, coaxial power feed and low level control system are presented. Calculations determining system performance are compared with measured values. Plans for future systems are discussed

Brookhaven highlights, fiscal year 1985, October 1, 1984-September 30, 1985

Energy Technology Data Exchange (ETDEWEB)

1985-01-01

Activities at Brookhaven National Laboratory are briefly discussed. These include work at the National Synchrotron Light Source, the High Flux Beam Reactor, and the Alternating Gradient Synchrotron. Areas of research include heavy ion reactions, neutrino oscillations, low-level waste, nuclear data, medicine, biology, chemistry, parallel computing, optics. Also provided are general and administrative news, a financial report. (LEW)

Brookhaven highlights, fiscal year 1985, October 1, 1984-September 30, 1985

International Nuclear Information System (INIS)

1985-01-01

Activities at Brookhaven National Laboratory are briefly discussed. These include work at the National Synchrotron Light Source, the High Flux Beam Reactor, and the Alternating Gradient Synchrotron. Areas of research include heavy ion reactions, neutrino oscillations, low-level waste, nuclear data, medicine, biology, chemistry, parallel computing, optics. Also provided are general and administrative news, a financial report

ATLAS Overview Week at Brookhaven

CERN Multimedia

Pilcher, J

Over 200 ATLAS participants gathered at Brookhaven National Laboratory during the first week of June for our annual overview week. Some system communities arrived early and held meetings on Saturday and Sunday, and the detector interface group (DIG) and Technical Coordination also took advantage of the time to discuss issues of interest for all detector systems. Sunday was also marked by a workshop on the possibilities for heavy ion physics with ATLAS. Beginning on Monday, and for the rest of the week, sessions were held in common in the well equipped Berkner Hall auditorium complex. Laptop computers became the norm for presentations and a wireless network kept laptop owners well connected. Most lunches and dinners were held on the lawn outside Berkner Hall. The weather was very cooperative and it was an extremely pleasant setting. This picture shows most of the participants from a view on the roof of Berkner Hall. Technical Coordination and Integration issues started the reports on Monday and became a...

Quasi-experimental designs in practice-based research settings: design and implementation considerations.

Science.gov (United States)

Handley, Margaret A; Schillinger, Dean; Shiboski, Stephen

2011-01-01

Although randomized controlled trials are often a gold standard for determining intervention effects, in the area of practice-based research (PBR), there are many situations in which individual randomization is not possible. Alternative approaches to evaluating interventions have received increased attention, particularly those that can retain elements of randomization such that they can be considered "controlled" trials. Methodological design elements and practical implementation considerations for two quasi-experimental design approaches that have considerable promise in PBR settings--the stepped-wedge design, and a variant of this design, a wait-list cross-over design, are presented along with a case study from a recent PBR intervention for patients with diabetes. PBR-relevant design features include: creation of a cohort over time that collects control data but allows all participants (clusters or patients) to receive the intervention; staggered introduction of clusters; multiple data collection points; and one-way cross-over into the intervention arm. Practical considerations include: randomization versus stratification, training run in phases; and extended time period for overall study completion. Several design features of practice based research studies can be adapted to local circumstances yet retain elements to improve methodological rigor. Studies that utilize these methods, such as the stepped-wedge design and the wait-list cross-over design, can increase the evidence base for controlled studies conducted within the complex environment of PBR.

Searching for the H-dibaryon at Brookhaven

International Nuclear Information System (INIS)

Bassalleck, B.; Athanas, M.; Berdoz, A.

1996-01-01

At the Brookhaven AGS several experiments are searching for the unique strangeness S = -2 H-dibaryon with the quark composition (uuddss). The E813/E836 collaboration, in particular, is using a high-intensity, separated 1.8 GeV/c K - beam and two different target configurations. In E836 the reaction K - + 3 He → K + + H + n is used to search for a relatively deeply-bound H. Complementary to E836 the reactions K - + p → Ξ + K + , followed by (Ξ - , d) atom → H + n are used to search near twice the Λ mass. The status of these two experiments is summarized, and other H-dibaryon searches are briefly reviewed. (author)

Proceedings of Brookhaven National Laboratory's fusion/synfuel workshop

International Nuclear Information System (INIS)

Fillo, J.A.; Powell, J.R.

1979-01-01

The fusion synfuels workshop held at Brookhaven National Laboratory (BNL) on August 27-29, 1979 examined the current status of candidate synfuel processes and the R and D required to develop the capability for fusion synfuel production. Participants divided into five working groups, covering the following areas: (1) economics and applications; (2) high-temperature electrolysis; (3) thermochemical processes (including hybrid thermo-electrochemical); (4) blanket and materials; and (5) high-efficiency power cycles. Each working group presented a summary of their conclusions and recommendations to all participants during the third day of the Workshop. These summaries are given

Current Practices in Global/International Advanced Pharmacy Practice Experiences: Preceptor and Student Considerations.

Science.gov (United States)

Dornblaser, Emily K; Ratka, Anna; Gleason, Shaun E; Ombengi, David N; Tofade, Toyin; Wigle, Patricia R; Zapantis, Antonia; Ryan, Melody; Connor, Sharon; Jonkman, Lauren J; Ochs, Leslie; Jungnickel, Paul W; Abrons, Jeanine P; Alsharif, Naser Z

2016-04-25

The objective of this article is to describe the key areas of consideration for global/international advanced pharmacy practice experience (G/I APPE) preceptors, students and learning objectives. At the 2013 Annual Meeting of the American Association of Colleges of Pharmacy (AACP), the GPE SIG prepared and presented an initial report on the G/IAPPE initiatives. Round table discussions were conducted at the 2014 AACP Annual Meeting to document GPE SIG member input on key areas in the report. Literature search of PubMed, Google Scholar and EMBASE with keywords was conducted to expand this report. In this paper, considerations related to preceptors and students and learning outcomes are described. Preceptors for G/I APPEs may vary based on the learning outcomes of the experience. Student learning outcomes for G/I APPEs may vary based on the type of experiential site. Recommendations and future directions for development of G/IAPPEs are presented. Development of a successful G/I APPE requires significant planning and consideration of appropriate qualifications for preceptors and students.

Science with multiply-charged ions at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Jones, K.W.; Johnson, B.M.; Meron, M.; Thieberger, P.

1987-01-01

The production of multiply-charged heavy ions at Brookhaven National Laboratory and their use in different types of experiments are discussed. The main facilities that are used are the Double MP Tandem Van de Graaff and the National Synchrotron Light Source. The capabilities of a versatile Atomic Physics Facility based on a combination of the two facilities and a possible new heavy-ion storage ring are summarized. It is emphasized that the production of heavy ions and the relevant science necessitates very flexible and diverse apparatus

Brookhaven National Laboratory site report for calendar year 1988

Energy Technology Data Exchange (ETDEWEB)

Miltenberger, R.P.; Royce, B.A.; Naidu, J.R.

1989-06-01

Brookhaven National Laboratory (BNL) is managed by Associated Universities Inc. (AUI). AUI was formed in 1946 by a group of nine universities whose purpose was to create and manage a laboratory in the Northeast in order to advance scientific research in areas of interest to universities, industry, and government. On January 31, 1947, the contract for BNL was approved by the Manhattan District of the Army Corps of Engineers and BNL was established on the former Camp Upton army camp. 54 refs., 21 figs., 78 tabs.

Brookhaven National Laboratory site report for calendar year 1988

International Nuclear Information System (INIS)

Miltenberger, R.P.; Royce, B.A.; Naidu, J.R.

1989-06-01

Brookhaven National Laboratory (BNL) is managed by Associated Universities Inc. (AUI). AUI was formed in 1946 by a group of nine universities whose purpose was to create and manage a laboratory in the Northeast in order to advance scientific research in areas of interest to universities, industry, and government. On January 31, 1947, the contract for BNL was approved by the Manhattan District of the Army Corps of Engineers and BNL was established on the former Camp Upton army camp. 54 refs., 21 figs., 78 tabs

The Fiftieth Anniversary of Brookhaven National Laboratory: A Turbulent Time

Science.gov (United States)

Bond, Peter D.

2018-03-01

The fiftieth anniversary year of Brookhaven National Laboratory was momentous, but for reasons other than celebrating its scientific accomplishments. Legacy environmental contamination, community unrest, politics, and internal Department of Energy issues dominated the year. It was the early days of perhaps the most turbulent time in the lab's history. The consequences resulted in significant changes at the lab, but in addition they brought a change to contracts to manage the Department of Energy laboratories.

Current Practices in Global/International Advanced Pharmacy Practice Experiences: Home/Host Country or Site/Institution Considerations.

Science.gov (United States)

Alsharif, Naser Z; Dakkuri, Adnan; Abrons, Jeanine P; Williams, Dennis; Ombengi, David N; Zheng, HaiAn; Al-Dahir, Sara; Tofade, Toyin; Gim, Suzanna; O'Connell, Mary Beth; Ratka, Anna; Dornblaser, Emily

2016-04-25

International outreach by schools and colleges of pharmacy is increasing. In this paper, we provide current practice guidelines to establish and maintain successful global/international advanced pharmacy practice experiences (G/I APPEs) with specific recommendations for home/host country and host site/institution. The paper is based on a literature review (2000-2014) in databases and Internet searches with specific keywords or terms. Educational documents such as syllabi and memoranda of understanding (MoUs) from pharmacy programs were also examined. In addition, a preliminary draft was developed and the findings and recommendations were reviewed in a 90-minute roundtable discussion at the 2014 American Association of Colleges of Pharmacy Annual Meeting. Recommendations for the host country include travel considerations (eg, passport, visa, air travel), safety, housing, transportation, travel alerts and warnings, health issues, and financial considerations. For the home country, considerations for establishment of G/I APPE site (eg, vetting process, MoU, site expectations) are described. The paper is a resource for development of new G/I APPEs and provides guidance for continuous quality improvement of partnerships focusing on G/I pharmacy education.

Brookhaven highlights, October 1978-September 1979

International Nuclear Information System (INIS)

1979-01-01

These highlights present an overview of the major research and development achievements at Brookhaven National Laboratory from October 1978 to September 1979. Specific areas covered include: accelerator and high energy physics programs; high energy physics research; the AGS and improvements to the AGS; neutral beam development; heavy ion fusion; superconducting power cables; ISABELLE storage rings; the BNL Tandem accelerator; heavy ion experiments at the Tandem; the High Flux Beam Reactor; medium energy physics; nuclear theory; atomic and applied physics; solid state physics; neutron scattering studies; x-ray scattering studies; solid state theory; defects and disorder in solids; surface physics; the National Synchrotron Light Source ; Chemistry Department; Biology Department; Medical Department; energy sciences; environmental sciences; energy technology programs; National Center for Analysis of Energy Systems; advanced reactor systems; nuclear safety; National Nuclear Data Center; nuclear materials safeguards; Applied Mathematics Department; and support activities

Brookhaven Reactor Experiment Control Facility, a distributed function computer network

International Nuclear Information System (INIS)

Dimmler, D.G.; Greenlaw, N.; Kelley, M.A.; Potter, D.W.; Rankowitz, S.; Stubblefield, F.W.

1975-11-01

A computer network for real-time data acquisition, monitoring and control of a series of experiments at the Brookhaven High Flux Beam Reactor has been developed and has been set into routine operation. This reactor experiment control facility presently services nine neutron spectrometers and one x-ray diffractometer. Several additional experiment connections are in progress. The architecture of the facility is based on a distributed function network concept. A statement of implementation and results is presented

Effective mass trigger at the Brookhaven Multi-Particle Spectrometer (MPS)

International Nuclear Information System (INIS)

Willen, E.H.

1980-01-01

An effective mass trigger for use at the Brookhaven Multiparticle Spectrometer (MPS) is described. It is a microprocessor based device using extensive fast memory attached to proportional wire chambers in the MPS magnetic field. It will select kinematic quantities unique to the reaction being studied, thereby permitting higher sensitivities and a reduction in data-processing cost for MPS experiments. The principles of operation for this trigger, and the results of simulations to assess its performance, are presented

Practical Considerations Informing Teachers' Technology Integration Decisions: The Case of Tablet PCs

Science.gov (United States)

Pareja Roblin, Natalie; Tondeur, Jo; Voogt, Joke; Bruggeman, Bram; Mathieu, Griet; van Braak, Johan

2018-01-01

The unique characteristics of tablet PCs promise important benefits for education. Yet, little is known about the rationale underlying teachers' decisions concerning their educational uses within the constraints of daily classroom practice. The current multiple case study investigated the practical considerations informing nine secondary school…

Elastic neutrino-electron scattering: a progress report on Exp734 at Brookhaven

International Nuclear Information System (INIS)

Abe, K.; Ahrens, L.A.; Amako, K.

1983-01-01

I will report preliminary results on elastic neutrino-electron scattering from data taken with the 200 ton segmented liquid scintillator - proportional drift-tube neutrino detector at Brookhaven. Features of the detector (such as the active target and long radiation length) permit a uniquely clean signal. Prospects of results from the completed analysis and further data taking are discussed

Practical considerations in developing an instrument-maintenance plan--

International Nuclear Information System (INIS)

Guth, M.A.S.

1989-01-01

The author develops a general set of considerations to explain how a consistent, well-organized, prioritized, and adequate time-allowance program plan for routine maintenance can be constructed. The analysis is supplemented with experience from the high flux isotope reactor (HFIR) at US Oak Ridge National Laboratory (ORNL). After the preventive maintenance (PM) problem was defined, the instruments on the schedule were selected based on the manufacturer's design specifications, quality-assurance requirements, prior classifications, experiences with the incidence of breakdowns or calibration, and dependencies among instruments. The effects of repair error in PM should be also studied. The HFIR requires three full-time technicians to perform both PM and unscheduled maintenance. A review is presented of concepts from queuing theory to determine anticipated breakdown patterns. In practice, the pneumatic instruments have a much longer lifetime than the electric/electronic instruments on various reactors at ORNL. Some special considerations and risk aversion in choosing a maintenance schedule

From nuclei to hypernuclei: A retrospective view of medium energy physics at Brookhaven

International Nuclear Information System (INIS)

Chrien, R.E.

2000-01-01

A new frontier in physics originated with programs at two Brookhaven National Laboratory facilities--the Cosmotron and the Alternating Gradient Synchrotron. The development of this frontier over a half century is described, as it turned from conventional nuclear physics to the hypernuclei and the study of strange matter

Brookhaven highlights. Report on research, October 1, 1992--September 30, 1993

Energy Technology Data Exchange (ETDEWEB)

Rowe, M.S.; Belford, M.; Cohen, A.; Greenberg, D.; Seubert, L. [eds.

1993-12-31

This report highlights the research activities of Brookhaven National Laboratory during the period dating from October 1, 1992 through September 30, 1993. There are contributions to the report from different programs and departments within the laboratory. These include technology transfer, RHIC, Alternating Gradient Synchrotron, physics, biology, national synchrotron light source, applied science, medical science, advanced technology, chemistry, reactor physics, safety and environmental protection, instrumentation, and computing and communications.

75 FR 55631 - U. S. Rail Corporation-Construction and Operation Exemption-Brookhaven Rail Terminal

Science.gov (United States)

2010-09-13

... the proposed construction is to enable U. S. Rail to serve the BRT as a common carrier and to deliver... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35141] U. S. Rail Corporation--Construction and Operation Exemption-- Brookhaven Rail Terminal AGENCY: Surface Transportation...

Brookhaven Lab physicist William Willis wins the 2003 W.K.H. Panofsky prize

CERN Multimedia

2003-01-01

William Willis, a senior physicist Brookhaven National Laboratory, has won the American Physical Society's 2003 W.K.H. Panofsky Prize in Experimental Particle Physics. He received the prize, which consists of $5,000 and a certificate citing his contributions to physics, at the APS meeting in Philadelphia on April 6 (1 page).

Early history of the Cosmotron and AGS at Brookhaven

International Nuclear Information System (INIS)

Courant, E.D.

1989-01-01

Early work is described on the design and construction of the two Brookhaven particle accelerators of the 1950s, the Cosmotron and the AGS (alternating-gradient synchrotron). The Cosmotron, finished by the Spring of 1952, was the smaller machine reaching 3GeV and was the first to pass the billion electron volt mark. Suggested alterations to magnet orientations meant that the alternating gradients produced would stabilize the design. This ''strong-focusing'' idea was central to the second AGS machine, which also overcame the problems of resonances and transition energy, with the inclusion of an electron analog accelerator. (UK)

First experiences with a fastbus system at Brookhaven

International Nuclear Information System (INIS)

Leipuner, L.B.; Larsen, R.C.; Makowiecki, D.S.

1980-01-01

A new concept in high energy data acquisition systems called Fastbus has been developed and implemented at Brookhaven. The system which is capable of sub-gigabit/sec speeds has been operating for some time now. A number of modules including an on-bus processor, a PDP11 interface, 32 channel coincidence latches, a 16 channel scaler, a 32 channel μ-clock device, a 60 nsec memory and a predetermined time module have been developed and built. Features of the system include extensive use of ECL logic and a water cooled crate with conduction heat transfer within a module. The system is used in an on-line experiment at the AGS. Operating experience will be discussed

Digital transverse beam dampers from the Brookhaven AGS

International Nuclear Information System (INIS)

Smith, G.A.; Castillo, V.; Roser, T.; Van Asselt, W.; Witkover, R.; Wong, V.

1995-01-01

A wide band, digital damper system has been developed and is in use at the Brookhaven Alternating Gradient Synchrotron (AGS). The system consists of vertical and horizontal capacitive pickups, analog and digital processing electronics, four 500 Watt wide band power amplifiers, and two pairs of strip line beam kickers. The system is currently used to damp transverse coherent instabilities and injection errors, in both planes, for protons and all species of heavy ions. This paper discusses the system design and operation, particularly with regard to stabilization of the high intensity proton beam. The analog and digital signal processing techniques used to achieve optimum results are discussed. Operational data showing the effect of the damping are presented

"Journal of Space Economics - theoretical and practical considerations"

Science.gov (United States)

Beldavs, VZ; Sommers, J.

2017-09-01

This paper will address theoretical and practical considerations for the emerging field of space economics and propose an editorial policy for a journal of space economics to provide a forum for the discussion of space economics issues. It is anticipated that initially the Journal of Space Economics will operate from two different nodes one offering a European perspective (University of Latvia) and the other a U.S. perspective (University of Wisconsin at Milwaukee). The first edition of the Journal of Space Economics will focus on issues likely to arise during the course of the International Lunar Decade 2020-2030.

Brookhaven four-stage accel-decel production of low-energy highly stripped heavy ions

International Nuclear Information System (INIS)

Barrette, J.; Thieberger, P.

1981-01-01

The dual MP tandem facility at Brookhaven has been used in a four-stage accel-decel mode to produce highly stripped S ion beams (Q = 10-16 + ). Fully stripped S ions were obtained at energies down to 8 MeV. The low energy limit is presently due to the inclined field configuration of the last acceleration tube

The Grumman/Brookhaven high-brightness, high-duty factor RF gun

International Nuclear Information System (INIS)

Lehrman, I.S.; Birnbaum, I.A.; Cole, M.; Fixler, S.Z.; Heuer, R.L.; Siddiqi, S.; Sheedy, E.; Waren, G.D.

1992-01-01

Under a joint collaboration between Brookhaven National Laboratory and the Grumman Corporation, a high-duty (>1%) photocathode RF gun is under construction for use at the ATF facility at BNL. The gun will be capable of producing short ( 300 A (after compression) and a total bunch charge in excess of 3 nC. The gun consists of 3-1/2 cells constructed from GlidCop, an alumina dispersion strengthened copper alloy. Two individually phased waveguides are used to power the first two and final two cells. (Author) 10 refs., 8 figs., 2 tabs

The Brookhaven Radiation Effects Facility

Energy Technology Data Exchange (ETDEWEB)

Grand, P.; Snead, C.L.; Ward, T.

1988-01-01

The Neutral Particle Beam (NPB) Radiation Effects Facility (REF), funded by the Strategic Defense Initiative Office (SDIO) through the Defense Nuclear Agency (DNA) and the Air Force Weapons Laboratory (AFWL), has been constructed at Brookhaven National Laboratory (BNL). Operation started in October 1986. The facility is capable of delivering pulsed H{sup -}, H{sup o}, and H{sup +} beams of 100 to 200 MeV energy up to 30 mA peak current. Pulses can be adjusted from 5 {mu}s to 500 {mu}s length at a repetition rate of 5 pps. The beam spot on target is adjustable from 3 to 100 cm diameter (2 {sigma}) resulting in a maximum dose of about 10 MRads (Si) per pulse (small beam spot). Experimental use of the REF is being primarily supported by the SDI lethality (LTH-4) program. The program has addressed ionization effects in electronics, both dose rate and total dose dependence, radiation-sensitive components, and dE/dx effects in energetic materials including propellants and high explosives (HE). This paper describes the facility, its capabilities and potential, and the experiments that have been carried out to date or are being planned. 2 refs., 10 figs.

The Brookhaven Radiation Effects Facility

International Nuclear Information System (INIS)

Grand, P.; Snead, C.L.; Ward, T.

1988-01-01

The Neutral Particle Beam (NPB) Radiation Effects Facility (REF), funded by the Strategic Defense Initiative Office (SDIO) through the Defense Nuclear Agency (DNA) and the Air Force Weapons Laboratory (AFWL), has been constructed at Brookhaven National Laboratory (BNL). Operation started in October 1986. The facility is capable of delivering pulsed H - , H/sup o/, and H + beams of 100 to 200 MeV energy up to 30 mA peak current. Pulses can be adjusted from 5 μs to 500 μs length at a repetition rate of 5 pps. The beam spot on target is adjustable from 3 to 100 cm diameter (2 σ) resulting in a maximum dose of about 10 MRads (Si) per pulse (small beam spot). Experimental use of the REF is being primarily supported by the SDI lethality (LTH-4) program. The program has addressed ionization effects in electronics, both dose rate and total dose dependence, radiation-sensitive components, and dE/dx effects in energetic materials including propellants and high explosives (HE). This paper describes the facility, its capabilities and potential, and the experiments that have been carried out to date or are being planned. 2 refs., 10 figs

BROOKHAVEN: Major detectors for RHIC under construction

International Nuclear Information System (INIS)

Ludlam, Thomas W.

1994-01-01

On March 9-10, a cost and schedule review at Brookhaven verified construction readiness for the PHENIX detector (May 1993, page 10). PHENIX thus joins STAR (Solenoidal Tracking at RHIC - November 1991, page 17), whose construction plan was ratified in January 1993, as a major detector to take data when the RHIC heavy ion collider is completed in mid-1999. The goal of both detectors is to search for the transition from ordinary nuclear matter to a new state of matter consisting of (momentarily) unconfined quarks and gluons. This transition to a ''quark-gluon plasma'' (QGP) is predicted to occur under extreme conditions of temperature and energy density, as is likely to be the case in the collision of heavy ions of sufficient energy. RHIC is expected to produce the highest energy densities ever observed on the nuclear scale

The new Brookhaven $(g-2)_{\\mu}$ experiment

CERN Document Server

Hertzog, D W; Bunce, G M; Carey, R M; Cushman, P B; Danby, G T; Debevec, P T; Deng, H; Deninger, W J; Dhawan, S K; Druzhinin, V P; Duong, L; Earle, W; Efstathiadis, E F; Farley, Francis J M; Fedotovich, G V; Giron, S; Gray, F; Grosse-Perdekamp, M; Grossmann, A; Haeberlen, U; Hare, M; Hazen, E S; Hughes, V W; Iwassaki, M; Jungmann, Klaus; Kawall, D; Kawamura, M; Khazin, B I; Kindem, J; Krienen, F; Kronkvist, I J; Larsen, R; Lee, Y Y; Liu, W; Logashenko, I B; McNabb, R; Meng, W; Mi, J L; Miller, J P; Morse, W M; Onderwater, Gerco; Orlov, Yu F; Pai, C; Polly, C; Pretz, J; Prigl, R; zu Putlitz, Gisbert; Redin, S I; Rind, O; Roberts, B L; Ryskulov, N M; Sanders, R; Sedykh, S N; Semertzidis, Y K; Serednyakov, S I; Shatunov, Yu M; Solodov, E P; Sossong, M; Steinmetz, A; Sulak, Lawrence R; Timmermans, C; Trofimov, A V; Urner, D; Warburton, D; Winn, D; Xu, Q; Yamamoto, A; Zimmerman, D

1999-01-01

A new assault on the muon's anomalous magnetic moment has begun with a vigorous effort by the Brookhaven E821 collaboration. The present group has refined the design used in a series of successful CERN experiments in order to lower the systematic uncertainties. Consequently it will be possible to take advantage of the greatly increased muon flux provided for at the AGS. Several novel techniques are employed, of which the most significant is a direct muon injection scheme. Upon reaching the goal of the experiment, comparison with theory will offer sensitive teats of both the electroweak corrections and physics beyond the standard model. At the time of this symposium, data from the first engineering run has been analyzed, yielding a result whose precision and value are comparable to those generated by the last CERN effort. (23 refs).

Is Overeating Behavior Similar to Drug Addiction? (427th Brookhaven Lecture)

Energy Technology Data Exchange (ETDEWEB)

Wang, Gene-Jack

2007-09-27

The increasing number of obese individuals in the U.S. and other countries world-wide adds urgency to the need to understand the mechanisms underlying pathological overeating. Research by the speaker and others at Brookhaven National Laboratory and elsewhere is compiling evidence that the brain circuits disrupted in obesity are similar to those involved in drug addiction. Using positron emission tomography (PET), the speaker and his colleagues have implicated brain dopamine in the normal and the pathological intake of food by humans. During the 427th Brookhaven Lecture, speaker will review the findings and implications of PET studies of obese subjects and then compare them to PET research involving drug-addicted individuals. For example, in pathologically obese subjects, it was found that reductions in striatal dopamine D2 receptors are similar to those observed in drug-addicted subjects. The speaker and his colleagues have postulated that decreased levels of dopamine receptors predisposed subjects to search for strongly rewarding reinforcers, be it drugs for the drug-addicted or food for the obese, as a means to compensate for decreased sensitivity of their dopamine-regulated reward circuits. As the speaker will summarize, multiple but similar brain circuits involved in reward, motivation, learning and inhibitory control are disrupted both in drug addiction and obesity, resulting in the need for a multimodal approach to the treatment of obesity.

The Next Generation of Heavy Ion Sources (447th Brookhaven Lecture)

International Nuclear Information System (INIS)

Okamura, Masahiro

2009-01-01

Imagine if, by staying in your lane when driving on the expressway, you could help fight cancer or provide a new, clean energy source. You would clench the steering wheel with both hands and stay in your lane, right? Unlike driving on the expressway where you intentionally avoid hitting other cars, scientists sometimes work to steer particle beams into head-on collisions with other oncoming particle beams. However, the particles must be kept 'in their lanes' for cleaner, more frequent collisions. Some scientists propose starting the whole process by using lasers to heat a fixed target as a way to get particles with higher charge, which are more steerable. These scientists believe the new methods could be used to develop particle beams for killing cancer cells or creating usable energy from fusion. Join Masahiro Okamura of Brookhaven's Collider-Accelerator Department for the 447th Brookhaven Lecture, titled 'The Next Generation of Heavy Ion Sources.' Okamura will explain how lasers can be used to create plasma, neutral mixtures of positive ions and negative electrons, from different materials, and how using this plasma leads to beams with higher charge states and currents. He will also discuss how this efficient, simpler method of producing particle beams might be used for cancer therapy, to develop new energy sources, or in synchrotrons.

Is Overeating Behavior Similar to Drug Addiction? (427th Brookhaven Lecture)

International Nuclear Information System (INIS)

Wang, Gene-Jack

2007-01-01

The increasing number of obese individuals in the U.S. and other countries world-wide adds urgency to the need to understand the mechanisms underlying pathological overeating. Research by the speaker and others at Brookhaven National Laboratory and elsewhere is compiling evidence that the brain circuits disrupted in obesity are similar to those involved in drug addiction. Using positron emission tomography (PET), the speaker and his colleagues have implicated brain dopamine in the normal and the pathological intake of food by humans. During the 427th Brookhaven Lecture, speaker will review the findings and implications of PET studies of obese subjects and then compare them to PET research involving drug-addicted individuals. For example, in pathologically obese subjects, it was found that reductions in striatal dopamine D2 receptors are similar to those observed in drug-addicted subjects. The speaker and his colleagues have postulated that decreased levels of dopamine receptors predisposed subjects to search for strongly rewarding reinforcers, be it drugs for the drug-addicted or food for the obese, as a means to compensate for decreased sensitivity of their dopamine-regulated reward circuits. As the speaker will summarize, multiple but similar brain circuits involved in reward, motivation, learning and inhibitory control are disrupted both in drug addiction and obesity, resulting in the need for a multimodal approach to the treatment of obesity.

1995 Annual epidemiologic surveillance report for Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-12-31

The US Department of Energy`s (DOE) conduct of epidemiologic surveillance provides an early warning system for health problems among workers. This program monitors illnesses and health conditions that result in an absence of five or more consecutive workdays, occupational injuries and illnesses, and disabilities and deaths among current workers. This report summarizes epidemiologic surveillance data collected from Brookhaven National Laboratory (BNL) from January 1, 1995 through December 31, 1995. The data were collected by a coordinator at BNL and submitted to the Epidemiologic Surveillance Data Center, located at Oak Ridge Institute for Science and Education, where quality control procedures and data analyses were carried out.

Interactive radiopharmaceutical facility between Yale Medical Center and Brookhaven National Laboratory. Progress report, October 1976-June 1979

Energy Technology Data Exchange (ETDEWEB)

Gottschalk, A.

1979-01-01

DOE Contract No. EY-76-S-02-4078 was started in October 1976 to set up an investigative radiochemical facility at the Yale Medical Center which would bridge the gap between current investigation with radionuclides at the Yale School of Medicine and the facilities in the Chemistry Department at the Brookhaven National Laboratory. To facilitate these goals, Dr. Mathew L. Thakur was recruited who joined the Yale University faculty in March of 1977. This report briefly summarizes our research accomplishments through the end of June 1979. These can be broadly classified into three categories: (1) research using indium-111 labelled cellular blood components; (2) development of new radiopharmaceuticals; and (3) interaction with Dr. Alfred Wolf and colleagues in the Chemistry Department of Brookhaven National Laboratory.

Interactive radiopharmaceutical facility between Yale Medical Center and Brookhaven National Laboratory. Progress report, October 1976-June 1979

International Nuclear Information System (INIS)

Gottschalk, A.

1979-01-01

DOE Contract No. EY-76-S-02-4078 was started in October 1976 to set up an investigative radiochemical facility at the Yale Medical Center which would bridge the gap between current investigation with radionuclides at the Yale School of Medicine and the facilities in the Chemistry Department at the Brookhaven National Laboratory. To facilitate these goals, Dr. Mathew L. Thakur was recruited who joined the Yale University faculty in March of 1977. This report briefly summarizes our research accomplishments through the end of June 1979. These can be broadly classified into three categories: (1) research using indium-111 labelled cellular blood components; (2) development of new radiopharmaceuticals; and (3) interaction with Dr. Alfred Wolf and colleagues in the Chemistry Department of Brookhaven National Laboratory

Practical Consideration Factors to Design Array Configuration of Direction Finding System for Airborne Signal Intelligence

Directory of Open Access Journals (Sweden)

Jong-Hwan Lee

2018-01-01

Full Text Available Airborne signal intelligence (SIGINT systems must be capable of locating radio signal sources. Direction finding (DF to support this capability is an important factor. There are some practical considerations to be taken when designing the array configuration of a DF system for airborne SIGINT systems. This paper summarizes the practical factors when designing the array configuration of the DF system for airborne SIGINT. In particular, it focuses on four areas: antenna consideration factors when installing the DF system for airborne SIGINT from a practical point of view, array configuration methods for airborne communications intelligence and electronic intelligence, and a numerical analysis to select the optimum antenna position for airborne SIGINT.

The first picosecond terawatt CO2 laser at the Brookhaven Accelerator Test Facility

International Nuclear Information System (INIS)

Pogorelsky, I.V.; Ben-Zvi, I.; Babzien, M.

1998-02-01

The first terawatt picosecond CO 2 laser will be brought to operation at the Brookhaven Accelerator Test Facility in 1998. System consists of a single-mode TEA oscillator, picosecond semiconductor optical switch, multi-atmosphere. The authors report on design, simulation, and performance tests of the 10 atm final amplifier that allows for direct multi-joule energy extraction in a picosecond laser pulse

A microwiggler Free-Electron Laser at the Brookhaven Accelerator Test Facility

International Nuclear Information System (INIS)

Batchelor, K.; Ben-Zvi, I.; Fernow, R.; Gallardo, J.; Kirk, H.; Pellegrini, C.; van Steenbergen, A.; Bhowmik, A.; Rockwell International Corp., Canoga Park, CA

1989-01-01

We report the design and status of an FEL experiment at the Brookhaven National Laboratory Accelerator Test Facility. A 50 MeV high brightness electron beam will be utilized for an oscillator experiment in the visible wavelength region. The microwiggler to be used is a superferric planar undulator with a 0.88 cm period, 60 cm length and K = 0.35. The optical cavity is a 368 cm long stable resonator with broadband dielectric coated mirrors. 8 refs., 2 figs., 4 tabs

Nuclear medicine at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Atkins, H.L.

1976-01-01

The Nuclear Medicine Program at the Brookhaven National Laboratory seeks to develop new materials and methods for the investigation of human physiology and disease processes. Some aspects of this research are related to basic research of how radiopharmaceuticals work. Other aspects are directed toward direct applications as diagnostic agents. It is likely that cyclotron-produced positron emitting nuclides will assume greater importance in the next few years. This can be attributed to the ability to label biologically important molecules with high specific activity without affecting biological activity, using 11 C, 13 N, and 15 O. Large quantities of these short-lived nuclides can be administered without excessive radiation dose and newer instrumentation will permit reconstructive axial tomography, providing truly quantitative display of distribution of radioactivity. The 122 Xe- 122 I generator has the potential for looking at rapid dynamic processes. Another generator, the 68 Ge- 68 Ga generator produces a positron emitter for the use of those far removed from cyclotrons. The possibilities for 68 Ga radiopharmaceuticals are as numerous as those for /sup 99m/Tc diagnostic agents

Proto-2, an ALICE detector prototype, part of the STAR experiment at the Brookhaven National Laboratory

CERN Multimedia

2002-01-01

Proto-2, an LAICE detector prototype, overcame its prototype status to become a real part of the SDTAR, epxeriment at the US Brookhaven National Laboratory. After more than two years across the ocean, it has just arrived back at CERN.

Brookhaven National Laboratory site environmental report for calendar year 1990

International Nuclear Information System (INIS)

Miltenberger, R.P.; Royce, B.A.; Naidu, J.R.

1992-01-01

Brookhaven National Laboratory (BNL) carries out basic and applied research in the following fields: high-energy nuclear and solid state physics; fundamental material and structure properties and the interactions of matter; nuclear medicine, biomedical and environmental sciences; and selected energy technologies. In conducting these research activities, it is Laboratory policy to protect the health and safety of employees and the public, and to minimize the impact of BNL operations on the environment. This document is the BNL environmental report for the calendar year 1990 for the safety and Environmental Protection division and corners topics on effluents, surveillance, regulations, assessments, and compliance

Brookhaven National Laboratory site environmental report for calendar year 1990

Energy Technology Data Exchange (ETDEWEB)

Miltenberger, R.P.; Royce, B.A.; Naidu, J.R.

1992-01-01

Brookhaven National Laboratory (BNL) carries out basic and applied research in the following fields: high-energy nuclear and solid state physics; fundamental material and structure properties and the interactions of matter; nuclear medicine, biomedical and environmental sciences; and selected energy technologies. In conducting these research activities, it is Laboratory policy to protect the health and safety of employees and the public, and to minimize the impact of BNL operations on the environment. This document is the BNL environmental report for the calendar year 1990 for the safety and Environmental Protection division and corners topics on effluents, surveillance, regulations, assessments, and compliance.

Mechanical support and transport system used for the neutrino horn system at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Walker, J.C.; Carroll, A.S.; Leonhardt, W.

1987-01-01

The study of neutrinos at the Alternating Gradient Synchrotron (AGS), Brookhaven National Laboratory (BNL), requires hardware for their initiation and control. The basics consist of a target, two horns and three collimators. This paper describes the installation, support and positioning of these components within a settling concrete blockhouse

POLARIZED BEAMS: 2 - Partial Siberian Snake rescues polarized protons at Brookhaven

International Nuclear Information System (INIS)

Huang, Haixin

1994-01-01

To boost the level of beam polarization (spin orientation), a partial 'Siberian Snake' was recently used to overcome imperfection depolarizing resonances in the Brookhaven Alternating Gradient Synchrotron (AGS). This 9-degree spin rotator recently permitted acceleration with no noticeable polarization loss. The intrinsic AGS depolarizing resonances (which degrade the polarization content) had been eliminated by betatron tune jumps, but the imperfection resonances were compensated by means of harmonic orbit corrections. However, at high energies these orbit corrections are difficult and tedious and a Siberian Snake became an attractive alternative

X-ray holographic microscopy experiments at the Brookhaven synchrotron light source

International Nuclear Information System (INIS)

Howells, M.R.; Iarocci, M.; Kenney, J.; Kirz, J.; Rarback, H.

1983-01-01

Soft x-ray holographic microscopy is discussed from an experimental point of view. Three series of measurements have been carried out using the Brookhaven 750 MeV storage ring as an x-ray source. Young slits fringes, Gabor (in line) holograms and various data pertaining to the soft x-ray performance of photographic plates are reported. The measurements are discussed in terms of the technique for recording them and the experimental limitations in effect. Some discussion is also given of the issues involved in reconstruction using visible light

Assessment and d/Deaf and Hard of Hearing Multilingual Learners: Considerations and Promising Practices.

Science.gov (United States)

Pizzo, Lianna; Chilvers, Amanda

2016-01-01

The authors address considerations and promising practices relating to assessment of d/Deaf and Hard of Hearing Multilingual Learners. DMLs' unique culture(s), language(s), and learning needs must be considered when assessments of this population are being planned, conducted, and interpreted. The authors address theory and research on (a) general considerations for the overarching assessment process, (b) specific assessment approaches used to assess DMLs, and (c) assessment of language proficiency for diverse language learners. In addition, basic recommendations for the assessment of DMLs are made, including increased availability of assessments in various languages, use of multiple sources of individual and family data, assessment of all languages, and incorporation of a strong assessment component (that includes nondiscrimination practices) into teacher preparation programs.

Physician to investigator: clinical practice to clinical research--ethical, operational, and financial considerations.

Science.gov (United States)

Pierre, Christine

2008-01-01

Physicians who participate in clinical research studies gain benefits for themselves, their practice, and their patients. Historically, private practice physicians have chosen to defer to their counterparts in academic medicine when it comes to contributing to scientific advancement through clinical studies. A growing number of private practice physicians are now taking a serious second look and deciding that there are unique benefits for both the practice and the patient. Physicians who decide to participate in clinical research should give serious consideration to the time and resources that are required to meet both federal regulations and industry standards. In addition, ethical and scientific principles for assuring the protection of human research subjects must be a paramount commitment.

Development of H- sources at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Prelec, K.

1977-01-01

Negative hydrogen ion sources have been developed at Brookhaven National Laboratory for several years, with the initial goal to design a source for accelerator applications and later on to design a large unit for applications in neutral beam injectors of magnetic fusion devices. Three types of sources were investigated, a hollow discharge duoplasmatron yielding H - currents up to 60 mA, a Penning source yielding H - currents up to 440 mA, and a magnetron source yielding H - currents up to 1 A. All sources operate with a mixture of hydrogen gas and cesium vapors, and H - ions are most likely produced on cesium covered electrode surfaces. A larger model of a Penning/magnetron source was constructed and will be tested soon; it incorporates among other new features a system for the cooling of the cathode

Beam vacuum system of Brookhaven's muon storage ring

International Nuclear Information System (INIS)

Hseuth, H.C.; Snydstrup, L.; Mapes, M.

1995-01-01

A storage ring with a circumference of 45 m is being built at Brookhaven to measure the g-2 value of the muons to an accuracy of 0.35 ppm.. The beam vacuum system of the storage ring will operate at 10 -7 Torr and has to be completely non-magnetic. It consists of twelve sector chambers. The chambers are constructed of aluminum and are approximately 3.5 m in length with a rectangular cross-section of 16.5 cm high by 45 cm at the widest point. The design features, fabrication techniques and cleaning methods for these chambers are described. The beam vacuum system will be pumped by forty eight non-magnetic distributed ion pumps with a total pumping speed of over 2000 ell/sec. Monte Carlo simulations of the pressure distribution in the muon storage region are presented

Brookhaven National Laboratory site environmental report for calendar year 1991

International Nuclear Information System (INIS)

Naidu, J.R.; Royce, B.A.; Miltenberger, R.P.

1992-09-01

This publication presents the results of BNL's environmental monitoring and compliance effort and provides an assessment of the impact of Brookhaven National Laboratory (BNL) operations on the environment. This document is the responsibility of the Environmental Protection Section of the Safety and Envirorunental Protection Division. Within this Section, the Environmental Monitoring Group (EMG) sample the environment, interpreted the results, performed the impact analysis of the emissions from BNL, and compiled the information presented here. In this effort, other groups of the Section: Compliance; Analytical; Ground Water; and Quality played a key role in addressing the regulatory aspects and the analysis and documentation of the data, respectively

Toward Catalyst Design from Theoretical Calculations (464th Brookhaven Lecture)

Energy Technology Data Exchange (ETDEWEB)

Liu, Ping (BNL Chemistry Dept)

2010-12-15

Catalysts have been used to speed up chemical reactions as long as yeast has been used to make bread rise. Today, catalysts are used everywhere from home kitchens to industrial chemical factories. In the near future, new catalysts being developed at Brookhaven Lab may be used to speed us along our roads and highways as they play a major role in solving the world’s energy challenges. During the lecture, Liu will discuss how theorists and experimentalists at BNL are working together to formulate and test new catalysts that could be used in real-life applications, such as hydrogen-fuel cells that may one day power our cars and trucks.

Brookhaven National Laboratory site environmental report for calendar year 1991

Energy Technology Data Exchange (ETDEWEB)

Naidu, J.R.; Royce, B.A.; Miltenberger, R.P.

1992-09-01

This publication presents the results of BNL's environmental monitoring and compliance effort and provides an assessment of the impact of Brookhaven National Laboratory (BNL) operations on the environment. This document is the responsibility of the Environmental Protection Section of the Safety and Envirorunental Protection Division. Within this Section, the Environmental Monitoring Group (EMG) sample the environment, interpreted the results, performed the impact analysis of the emissions from BNL, and compiled the information presented here. In this effort, other groups of the Section: Compliance; Analytical; Ground Water; and Quality played a key role in addressing the regulatory aspects and the analysis and documentation of the data, respectively.

Brookhaven National Laboratory site environmental report for calendar year 1991

Energy Technology Data Exchange (ETDEWEB)

Naidu, J.R.; Royce, B.A.; Miltenberger, R.P.

1992-09-01

This publication presents the results of BNL`s environmental monitoring and compliance effort and provides an assessment of the impact of Brookhaven National Laboratory (BNL) operations on the environment. This document is the responsibility of the Environmental Protection Section of the Safety and Envirorunental Protection Division. Within this Section, the Environmental Monitoring Group (EMG) sample the environment, interpreted the results, performed the impact analysis of the emissions from BNL, and compiled the information presented here. In this effort, other groups of the Section: Compliance; Analytical; Ground Water; and Quality played a key role in addressing the regulatory aspects and the analysis and documentation of the data, respectively.

2003 Brookhaven National Laboratory Annual Illness and Injury Surveillance Report, Revised September 2007

Energy Technology Data Exchange (ETDEWEB)

U.S. Department of Energy, Office of Health, Safety and Security, Office of Illness and Injury Prevention Programs

2007-10-02

Annual Illness and Injury Surveillance Program report for 2003 for Brookhaven National Lab. The U.S. Department of Energy’s (DOE) commitment to assuring the health and safety of its workers includes the conduct of epidemiologic surveillance activities that provide an early warning system for health problems among workers. The IISP monitors illnesses and health conditions that result in an absence of workdays, occupational injuries and illnesses, and disabilities and deaths among current workers.

Assessment of Energy Efficiency Project Financing Alternatives for Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Hunt, W. D.; Hail, John C.; Sullivan, Gregory P.

2000-02-14

This document provides findings and recommendations that resulted from an assessment of the Brookhaven National Laboratory by a team from Pacific Northwest National Laboratory to assess the site's potential for various alternative financing options as a means to implement energy-efficiency improvements. The assessment looked for life-cycle cost-effective energy-efficiency improvement opportunities, and through a series of staff interviews, evaluated the various methods by which these opportunities may be financed, while considering availability of funds, staff, and available financing options. This report summarizes the findings of the visit and the resulting recommendations.

Brookhaven National Laboratory electron beam test stand

International Nuclear Information System (INIS)

Pikin, A.; Alessi, J.; Beebe, E.; Kponou, A.; Prelec, K.; Snydstrup, L.

1998-01-01

The main purpose of the electron beam test stand (EBTS) project at the Brookhaven National Laboratory is to build a versatile device to develop technologies that are relevant for a high intensity electron beam ion source (EBIS) and to study the physics of ion confinement in a trap. The EBTS will have all the main attributes of EBIS: a 1-m-long, 5 T superconducting solenoid, electron gun, drift tube structure, electron collector, vacuum system, ion injection system, appropriate control, and instrumentation. Therefore it can be considered a short prototype of an EBIS for a relativistic heavy ion collider. The drift tube structure will be mounted in a vacuum tube inside a open-quotes warmclose quotes bore of a superconducting solenoid, it will be at room temperature, and its design will employ ultrahigh vacuum technology to reach the 10 -10 Torr level. The first gun to be tested will be a 10 A electron gun with high emission density and magnetic compression of the electron beam. copyright 1998 American Institute of Physics

Geothermal materials development at Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Kukacka, L.E. [Brookhaven National Lab., Upton, NY (United States)

1997-12-31

As part of the DOE/OGT response to recommendations and priorities established by industrial review of their overall R&D program, the Geothermal Materials Program at Brookhaven National Laboratory (BNL) is focusing on topics that can reduce O&M costs and increase competitiveness in foreign and domestic markets. Corrosion and scale control, well completion materials, and lost circulation control have high priorities. The first two topics are included in FY 1997 BNL activities, but work on lost circulation materials is constrained by budgetary limitations. The R&D, most of which is performed as cost-shared efforts with U.S. geothermal firms, is rapidly moving into field testing phases. FY 1996 and 1997 accomplishments in the development of lightweight CO{sub 2}-resistant cements for well completions; corrosion resistant, thermally conductive polymer matrix composites for heat exchange applications; and metallic, polymer and ceramic-based corrosion protective coatings are given in this paper. In addition, plans for work that commenced in March 1997 on thermally conductive cementitious grouting materials for use with geothermal heat pumps (GHP), are discussed.

Charge exchange studies with Gold ions at the Brookhaven Booster and AGS

International Nuclear Information System (INIS)

Ahrens, L.A.; Hseuh, H.C.; Roser, T.

1994-01-01

Efficient acceleration of Gold ions to ll GeV/nucleon places strong constraints on the vacuum and also on the choice of thickness and material of the necessary stripping foils. Results of a number of detailed experimental studies performed with the Gold beam at the Brookhaven Booster and AGS to determine the relevant electron stripping and pick-up probabilities are presented. Of particular interest is the lifetime of the relatively low energy, partially stripped Gold beam in the Booster and the stripping efficiency to Helium-like AU +77 for injection into the AGS

Risk-based priority scoring for Brookhaven National Laboratory environmental restoration programs

International Nuclear Information System (INIS)

Morris, S.C.; Meinhold, A.F.

1995-05-01

This report describes the process of estimating the risk associated with environmental restoration programs under the Brookhaven National Laboratory Office of Environmental Restoration. The process was part of an effort across all Department of Energy facilities to provide a consistent framework to communicate risk information about the facilities to senior managers in the DOE Office of Environmental Management to foster understanding of risk activities across programs. the risk evaluation was a qualitative exercise. Categories considered included: Public health and safety; site personnel safety and health; compliance; mission impact; cost-effective risk management; environmental protection; inherent worker risk; environmental effects of clean-up; and social, cultural, political, and economic impacts

Testing of a cryogenic recooler heat exchanger at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Nicoletti, A.; Wu, K.C.

1993-01-01

Brookhaven National Laboratory has tested a recooler heat exchanger intended to be used in the cryogenic system of the Relativistic Heavy Ion Collider. The unit is required to transfer 225 Watts from a supercritical helium stream flowing at 100 g/s to a helium bath boiling at 4.25 K. Measurements made with heat loads of 50 to over 450 Watts on the unit indicate its cooling capacity is greater than 400 Watts, as expected, and it will be suitable for use in the RHIC ring. Presented are the modifications made to BNL's MAGCOOL test facility that were necessary for testing, test procedure, and recooler performance

[Theoretical and practical considerations in rational polytherapy for epilepsy].

Science.gov (United States)

Rajna, Péter

2011-11-30

Author analyses the consideration of rational polytherapy for epilepsy. Among the theoretical aspects he points the different effect of seizure inhibitory drugs on the epilepsy models but didn't find data enough for the basis of any successful combination. Combinations of compounds having different way of action are more promising. Rational polytherapy can serve also the epileptic patients' tailored therapy in the daily routine. There have already been some proved synergisms concerning drug interactions. Based on detailed analysis of side effects a possibility occurs for neutralization of side effects when anticonvulsants with side effects of opposite nature are combined. Considering both the side effect profiles and the different (somatic and psychic) habits of the patients we can create a special list of favourable combinations. Co-morbid states and their treatments play a significant role in the application of rational polytherapy. Combination of anticonvulsants of lower potential but without drug-interactions can be the choice in these cases. The non-epileptic indications of the anticonvulsants can also be utilized in polymorbid patients. Based on the theoretical and practical considerations the author defines the ten-step-cognitive-preparation-process in planning the optimal (poly)therapy. On speculative basis he suggests eight beneficial versions of seizure inhibitory rational polytherapy.

Summary of failure analysis activities at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Cowgill, M.G.; Czajkowski, C.J.; Franz, E.M.

1996-10-01

Brookhaven National Laboratory has for many years conducted examinations related to the failures of nuclear materials and components. These examinations included the confirmation of root cause analyses, the determination of the causes of failure, identification of the species that accelerate corrosion, and comparison of the results of nondestructive examinations with those obtained by destructive examination. The results of those examinations, which had previously appeared in various formats (formal and informal reports, journal articles, etc.), have been collected together and summarized in the present report. The report is divided into sections according to the general subject matter (for example, corrosion, fatigue, etc.). Each section presents summaries of the information contained in specific reports and publications, all of which are fully identified as to title, authors, report number or journal reference, date of publication, and FIN number under which the work was performed

WILDLAND FIRE MANAGEMENT PLAN FOR BROOKHAVEN NATIONAL LABORATORY.

Energy Technology Data Exchange (ETDEWEB)

ENVIRONMENTAL AND WASTE MANAGEMENT SERVICES DIVISION

2003-09-01

This Wildland Fire Management Plan (FMP) for Brookhaven National Lab (BNL) and the Upton Ecological and Research Reserve (Upton Reserve) is based on the U.S. Fish & Wildlife Service (FWS) fire management planning procedures and was developed in cooperation with the Department of Energy (DOE) by Brookhaven Science Associates. As the Upton Reserve is contained within the BNL 5,265-acre site, it is logical that the plan applies to both the Upton Reserve and BNL. The Department of the Interior policy for managing wildland fires requires that all areas managed by FWS that can sustain fire must have an FMP that details fire management guidelines for operational procedures and specifies values to be protected or enhanced. Fire management plans provide guidance on fire preparedness, fire prevention, wildfire suppression, and the use of controlled, ''prescribed'' fires and mechanical means to control the amount of available combustible material. Values reflected in the BNL/Upton Reserve Wildland FMP include protecting life and public safety; Lab properties, structures and improvements; cultural and historical sites; neighboring private and public properties; and endangered and threatened species and species of concern. Other values supported by the plan include the enhancement of fire-dependent ecosystems at BNL and the Upton Reserve. This FMP will be reviewed periodically to ensure the fire program advances and evolves with the missions of FWS, BNL, and the Upton Reserve. This Fire Management Plan is a modified version of the Long Island National Wildlife Refuge Complex Fire plan (updated in 2000), which contains all FWS fire plan requirements and is presented in the format specified by the national template for fire management plans adopted under the National Fire Plan. The DOE is one of the signatory agencies on the National Fire Plan. FWS shall be, through an Interagency Agreement dated November 2000 (Appendix C), responsible for coordinating and

Use of Neutron Irradiations in the Brookhaven Mutations Programme; Irradiation Neutronique dans le Cadre du Programme de Mutations Radioinduites de Brookhaven; Primenenie nejtronnogo izlucheniya v brukkhejvenskoj programme po ispol'zovaniyu mutatsij; La Irradiacion Neutronica en el Marco del Programa de Mutaciones Radioinducidas de Brookhaven

Energy Technology Data Exchange (ETDEWEB)

Miksche, J. P.; Shapiro, S. [Biology Department, Brookhaven National Laboratory, Upton, NY (United States)

1964-03-15

The Co-operative Radiation-Mutations Programme was established at Brookhaven National Laboratory approximately ten years ago to enable plant breeders and agriculturalists to make use of irradiation techniques in plant improvement programmes. The radiation facilities used in the programme are the thermal neutron column at the BGRR reactor, the 250-kVp X-ray machine in the Biology Department, the kilocurie gamma-sources in the Nuclear Engineering Department, a 12 c Co{sup 60} gamma-source in the greenhouse, and a 4000 c Co{sup 60} source located in a 13-acre field. The development of facilities, techniques, and theory represent Brookhaven's role in this cooperative project whereas the plant material and seed are provided by agricultural experts who are responsible for growing the irradiated material and screening for mutations. More than 150 scientists in 45 states and Puerto Rico are availing themselves of the programme's facilities. Projects have also initiated with Australia, Belgium, Chile, Costa Rica, Denmark, Ecuador, Formosa, Greece, Guatemala, India, Ireland, Italy, Japan, Kenya, Mexico, the Netherlands, Pakistan, Peru, the Philippines, Romania, South Africa.Thailand, Venezuela, West Germany and Yugoslavia. A review of the above cc-operative projects is presented with emphasis on the use of neutrons in mutation induction. (author) [French] Le programme commun de mutations radioinduites a ete mis en oeuvre, il y a une dizaine d'annees, au Laboratoire national de Brookhaven pour permettre aux phytogeneticiens et aux agronomes d'ameliorer les cultures a l 'aide des rayonnements. Les installations utilisees dans le cadre de ce programme sont les suivantes: colonne thermique du reacteur BGRR, appareil a rayons X de 250 kV-crete du Departement de biologie, sources de rayons gamma de 1000 c du Departement du genie nucleaire, source au {sup 60}Co de 12 c dans la serre et source au {sup 60}Co de 4000 c dans un champ experimental de 5 ha. Le role du Laboratoire deBrookhaven

Deriving cleanup guidelines for radionuclides at Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Meinhold, A.F.; Morris, S.C.; Dionne, B.; Moskowitz, P.D.

1997-01-01

Past activities at Brookhaven National Laboratory (BNL) resulted in soil and groundwater contamination. As a result, BNL was designated a Superfund site under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA). BNL`s Office of Environmental Restoration (OER) is overseeing environmental restoration activities at the Laboratory. With the exception of radium, there are no regulations or guidelines to establish cleanup guidelines for radionuclides in soils at BNL. BNL must derive radionuclide soil cleanup guidelines for a number of Operable Units (OUs) and Areas of Concern (AOCs). These guidelines are required by DOE under a proposed regulation for radiation protection of public health and the environment as well as to satisfy the requirements of CERCLA. The objective of this report is to propose a standard approach to deriving risk-based cleanup guidelines for radionuclides in soil at BNL. Implementation of the approach is briefly discussed.

Deriving cleanup guidelines for radionuclides at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Meinhold, A.F.; Morris, S.C.; Dionne, B.; Moskowitz, P.D.

1997-01-01

Past activities at Brookhaven National Laboratory (BNL) resulted in soil and groundwater contamination. As a result, BNL was designated a Superfund site under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA). BNL's Office of Environmental Restoration (OER) is overseeing environmental restoration activities at the Laboratory. With the exception of radium, there are no regulations or guidelines to establish cleanup guidelines for radionuclides in soils at BNL. BNL must derive radionuclide soil cleanup guidelines for a number of Operable Units (OUs) and Areas of Concern (AOCs). These guidelines are required by DOE under a proposed regulation for radiation protection of public health and the environment as well as to satisfy the requirements of CERCLA. The objective of this report is to propose a standard approach to deriving risk-based cleanup guidelines for radionuclides in soil at BNL. Implementation of the approach is briefly discussed

Assessment and d/Deaf and Hard of Hearing Multilingual Learners: Considerations and Promising Practices

Science.gov (United States)

Pizzo, Lianna; Chilvers, Amanda

2016-01-01

The authors address considerations and promising practices relating to assessment of d/Deaf and Hard of Hearing Multilingual Learners. DMLs' unique culture(s), language(s), and learning needs must be considered when assessments of this population are being planned, conducted, and interpreted. The authors address theory and research on (a) general…

Pulsed-neutron production at the Brookhaven 200-MeV linac

International Nuclear Information System (INIS)

Ward, T.E.; Alessi, J.; Brennan, J.; Grand, P.; Lankshear, R.; Montemurro, P.; Snead, C.L. Jr.; Tsoupas, N.

1988-01-01

The new 750-kV RFQ preinjector and double chopper system capable of selecting single nanosecond micropulses with repetition rates of 0.1--20 MHz has been installed at the Brookhaven 200-MeV proton linac. The micropulse intensity is approximately 1 x 10 9 p/μpulse. Neutron time-of-flight path lengths of 30--100 meter at 0/degree/, 12/degree/, 30/degree/, 45/degree/, 90/degree/ and 135/degree/ are available, as well as a zero degree swinger capable of an angular range of 0--25/degree/. Pulsed neutron beams of monoenergetic (p 7 Li → n 7 Be) and spallation (p 238 U → nx) sources will be discussed in the present paper, as well as detailing the chopped-beam capabilities. 11 refs., 5 figs., 1 tab

The Quest for High Luminosity in Hadron Colliders (413th Brookhaven Lecture)

International Nuclear Information System (INIS)

Fischer, Wolfram

2006-01-01

In 1909, by bombarding a gold foil with alpha particles from a radioactive source, Ernest Rutherford and coworkers learned that the atom is made of a nucleus surrounded by an electron cloud. Ever since, scientists have been probing deeper and deeper into the structure of matter using the same technique. With increasingly powerful machines, they accelerate beams of particles to higher and higher energies, to penetrate more forcefully into the matter being investigated and reveal more about the contents and behavior of the unknown particle world. To achieve the highest collision energies, projectile particles must be as heavy as possible, and collide not with a fixed target but another beam traveling in the opposite direction. These experiments are done in machines called hadron colliders, which are some of the largest and most complex research tools in science. Five such machines have been built and operated, with Brookhaven's Relativistic Heavy Ion Collider (RHIC) currently the record holder for the total collision energy. One more such machine is under construction. Colliders have two vital performance parameters on which their success depends: one is their collision energy, and the other, the number of particle collisions they can produce, which is proportional to a quantity known as the luminosity. One of the tremendous achievements in the world's latest collider, RHIC, is the amazing luminosity that it produces in addition to its high energy. To learn about the performance evolution of these colliders and the way almost insurmountable difficulties can be overcome, especially in RHIC, join Wolfram Fischer, a physicist in the Collider-Accelerator (C-A) Department, who will give the next Brookhaven Lecture, on 'The Quest for High Luminosity in Hadron Colliders.'

CULTURAL RESOURCE MANAGEMENT PLAN FOR BROOKHAVEN NATIONAL LABORATORY.

Energy Technology Data Exchange (ETDEWEB)

DAVIS, M.

2005-04-01

The Cultural Resource Management Plan (CRMP) for Brookhaven National Laboratory (BNL) provides an organized guide that describes or references all facets and interrelationships of cultural resources at BNL. This document specifically follows, where applicable, the format of the U.S. Department of Energy (DOE) Environmental Guidelines for Development of Cultural Resource Management Plans, DOE G 450.1-3 (9-22-04[m1]). Management strategies included within this CRMP are designed to adequately identify the cultural resources that BNL and DOE consider significant and to acknowledge associated management actions. A principal objective of the CRMP is to reduce the need for additional regulatory documents and to serve as the basis for a formal agreement between the DOE and the New York State Historic Preservation Officer (NYSHPO). The BNL CRMP is designed to be a ''living document.'' Each section includes identified gaps in the management plan, with proposed goals and actions for addressing each gap. The plan will be periodically revised to incorporate new documentation.

Tiger Team assessment of the Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

1990-06-01

This report documents the results of the Department of Energy's (DOE's) Tiger Team Assessment conducted at Brookhaven National Laboratory (BNL) in Upton, New York, between March 26 and April 27, 1990. The BNL is a multiprogram laboratory operated by the Associated Universities, Inc., (AUI) for DOE. The purpose of the assessment was to provide the status of environment, safety, and health (ES H) programs at the laboratory. The scope of the assessment included a review of management systems and operating procedures and records; observations of facility operations; and interviews at the facilities. Subteams in four areas performed the review: ES H, Occupational Safety and Health, and Management and Organization. The assessment was comprehensive, covering all areas of ES H activities and waste management operations. Compliance with applicable Federal, State, and local regulations; applicable DOE Orders; and internal BNL requirements was assessed. In addition, the assessment included an evaluation of the adequacy and effectiveness of the DOE and the site contractor, Associated Universities, Inc. (AUI), management, organization, and administration of the ES H programs at BNL. This volume contains appendices.

Tiger Team assessment of the Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

1990-06-01

This report documents the results of the Department of Energy's (DOE's) Tiger Team Assessment conducted at Brookhaven National Laboratory (BNL) in Upton, New York, between March 26 and April 27, 1990. The BNL is a multiprogram laboratory operated by the Associated Universities, Inc., (AUI) for DOE. The purpose of the assessment was to provide the status of environment, safety, and health (ES H) programs at the Laboratory. The scope of the assessment included a review of management systems and operating procedures and records; observations of facility operations; and interviews at the facilities. Subteams in four areas performed the review: ES H, Occupational Safety and Health, and Management and Organization. The assessment was comprehensive, covering all areas of ES H activities and waste management operations. Compliance with applicable Federal, State, and local regulations; applicable DOE Orders; and internal BNL requirements was assessed. In addition, the assessment included an evaluation of the adequacy and effectiveness of the DOE and the site contractor, Associated Universities, Inc. (AUI), management, organization, and administration of the ES H programs at BNL.

Practical considerations for disaster preparedness and continuity management in research facilities.

Science.gov (United States)

Mortell, Norman; Nicholls, Sam

2013-10-01

Many research facility managers, veterinarians and directors are familiar with the principles of Good Laboratory Practice, requirements of the Association for Assessment and Accreditation of Laboratory Animal Care International, tenets of biosecurity and standards of animal welfare and housing but may be less familiar with the ideas of business continuity. But business continuity considerations are as applicable to research facilities as they are to other institutions. The authors discuss how business continuity principles can be applied in the research context and propose that such application, or 'research continuity management,' enables a focused but wide-reaching approach to disaster preparedness.

Korean older intimate partner violence survivors in North America: cultural considerations and practice recommendations.

Science.gov (United States)

Shim, Woochan S; Nelson-Becker, Holly

2009-01-01

While literature on elder abuse has expanded, elder abuse by intimate partners has been less investigated. Even less is known about intimate partner violence among older Koreans living in North America. This article identifies important cultural considerations for individuals helping the Korean older adult community, beginning with the definition of intimate partner violence in this community and barriers to leaving that include traditional views of the East Asian self. Current practice interventions are discussed and recommendations for future practice such as healing han, the accumulated suffering from years of abuse, are suggested. The ultimate goal of this paper is to expand awareness in order to develop the best culturally competent prevention and intervention practice for Korean older intimate partner violence survivors in North America.

Short-lived radionuclide production capability at the Brookhaven Linac Isotope Producer

International Nuclear Information System (INIS)

Mausner, L.F.; Richards, P.

1985-01-01

The Brookhaven National Linac Isotope Producer is the first facility to demonstrate the capability of a large linear accelerator for efficient and economical production of difficult-to-make, medically useful radionuclides. The linac provides a beam of 200-MeV protons at an integrated beam current of up to 60 μA. The 200-MeV proton energy is very suitable for isotope production because the spallation process can create radionuclides unavailable at lower energy accelerators or reactors. Several medically important short-lived radionuclides are presently being prepared for on-site and off-site collaborative research programs. These are iodine-123, iron-52, manganese-52m, ruthenium-97, and the rubidium-81-krypton-81m system. The production parameters for these are summarized

Seismic hazard studies for the high flux beam reactor at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Costantino, C.J.; Heymsfield, E.; Park, Y.J.; Hofmayer, C.H.

1991-01-01

This paper presents the results of a calculation to determine the site specific seismic hazard appropriate for the deep soil site at Brookhaven National Laboratory (BNL) which is to be used in the risk assessment studies being conducted for the High Flux Beam Reactor (HFBR). The calculations use as input the seismic hazard defined for the bedrock outcrop by a study conducted at Lawrence Livermore National Laboratory (LLNL). Variability in site soil properties were included in the calculations to obtain the seismic hazard at the ground surface and compare these results with those using the generic amplification factors from the LLNL study

Laser ion source with solenoid for Brookhaven National Laboratory-electron beam ion source.

Science.gov (United States)

Kondo, K; Yamamoto, T; Sekine, M; Okamura, M

2012-02-01

The electron beam ion source (EBIS) preinjector at Brookhaven National Laboratory (BNL) is a new heavy ion-preinjector for relativistic heavy ion collider (RHIC) and NASA Space Radiation Laboratory (NSRL). Laser ion source (LIS) is a primary ion source provider for the BNL-EBIS. LIS with solenoid at the plasma drift section can realize the low peak current (∼100 μA) with high charge (∼10 nC) which is the BNL-EBIS requirement. The gap between two solenoids does not cause serious plasma current decay, which helps us to make up the BNL-EBIS beamline.

Laser ion source with solenoid for Brookhaven National Laboratory-electron beam ion source

International Nuclear Information System (INIS)

Kondo, K.; Okamura, M.; Yamamoto, T.; Sekine, M.

2012-01-01

The electron beam ion source (EBIS) preinjector at Brookhaven National Laboratory (BNL) is a new heavy ion-preinjector for relativistic heavy ion collider (RHIC) and NASA Space Radiation Laboratory (NSRL). Laser ion source (LIS) is a primary ion source provider for the BNL-EBIS. LIS with solenoid at the plasma drift section can realize the low peak current (∼100 μA) with high charge (∼10 nC) which is the BNL-EBIS requirement. The gap between two solenoids does not cause serious plasma current decay, which helps us to make up the BNL-EBIS beamline.

Laser ion source with solenoid for Brookhaven National Laboratory-electron beam ion sourcea)

Science.gov (United States)

Kondo, K.; Yamamoto, T.; Sekine, M.; Okamura, M.

2012-02-01

The electron beam ion source (EBIS) preinjector at Brookhaven National Laboratory (BNL) is a new heavy ion-preinjector for relativistic heavy ion collider (RHIC) and NASA Space Radiation Laboratory (NSRL). Laser ion source (LIS) is a primary ion source provider for the BNL-EBIS. LIS with solenoid at the plasma drift section can realize the low peak current (˜100 μA) with high charge (˜10 nC) which is the BNL-EBIS requirement. The gap between two solenoids does not cause serious plasma current decay, which helps us to make up the BNL-EBIS beamline.

Pulsed-neutron production at the Brookhaven 200-MeV linac

International Nuclear Information System (INIS)

Ward, T.E.; Alessi, J.; Brennan, J.; Grand, P.; Lankshear, R.; Montemurro, P.; Snead, C.L. Jr.; Tsoupas, N.

1989-01-01

The new 750-kV RFQ preinjector and double chopper system capable of selecting single nanosecond micropulses with repetition rates of 0.1 to 20 MHz has been installed at the Brookhaven 200-MeV proton linac. The micropulse intensity is approximately 1 x 10 9 p/μpulse. Neutron time-of-flight path lengths of 30 to 100 meters at 0 degree, 12 degree, 30 degree, 45 degree, 90 degree and 135 degree are available as well as a zero-degree beam swinger capable of an angular range of 0 degree to 25 degree. Pulsed neutron beams of monoenergetic (p 7 Li → n 7 Be) and spallation (p 238 U → nx) sources will be discussed in the present paper as well as detailing the chopped-beam capabilities. 11 refs., 5 figs., 1 tab

Summer school in nuclear and radiochemistry at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Kolsky, K.L.

2005-01-01

The U.S. Department of Energy supports 24 fellowships for students to attend six-week programs at either San Jose State University in California, or Brookhaven National Laboratory (BNL) in New York. The American Chemical Society through the Division of Nuclear Science and Technology operates both schools. The twelve students at the BNL program are enrolled in the State University of New York at Stony Brook (SUNYSB) and receive 3 college credits for the lecture course (CHE-361) and 3 additional credits for the laboratory course (CHE-362). In addition to lectures and laboratories, students tour various nuclear facilities offsite, at BNL, and at SUNYSB. Opportunities are given the students to interact with faculty and scientists within the profession through the Guest Lecture Program. Further details are discussed along with results of student surveys for the years 1999 through 2002. (author)

Report on the Brookhaven solar neutrino experiment

International Nuclear Information System (INIS)

Davis, R. Jr.; Evans, J.C. Jr.

1976-01-01

This report is intended as a brief statement of the recent developments and results of the Brookhaven Solar Neutrino Experiment communicated through Professor G. Kocharov to the Leningrad conference on active processes on the sun and the solar neutrino problem. The report summarizes the results of experiments performed over a period of 6 years, from April 1970 to January 1976. Neutrino detection depends upon the neutrino capture reaction 37 Cl(ν,e - ) 37 Ar producing the isotope 37 Ar (half life of 35 days). The detector contains 3.8 x 10 5 liters of C 2 Cl 4 (2.2 x 10 30 atoms of 37 Cl) and is located at a depth of 4400 meters of water equivalent (m.w.e.) in the Homestake Gold Mine at Lead, South Dakota, U.S.A. The procedures for extracting 37 Ar and the counting techniques used were described in previous reports. The entire recovered argon sample was counted in a small gas proportional counter. Argon-37 decay events were characterized by the energy of the Auger electrons emitted following the electron capture decay and by the rise-time of the pulse. Counting measurements were continued for a period sufficiently long to observe the decay of 37 Ar

Increased intensity performance of the Brookhaven AGS

International Nuclear Information System (INIS)

Raka, E.; Ahrens, L.; Frey, W.; Gill, E.; Glenn, J.W.; Sanders, R.; Weng, W.

1985-05-01

With the advent of H - injection into the Brookhaven AGS, circulating beams of up to 3 x 10 13 protons at 200 MeV have been obtained. Rf capture of 2.2 x 10 13 and acceleration of 1.73 x 10 13 up to the transition energy (approx. = 8 GeV) and 1.64 x 10 13 to full energy (approx. = 29 GeV) has been achieved. This represents a 50% increase over the best performance obtained with H + injection. The increase in circulation beam current is obtained without filling the horizontal aperture. This allows the rf capture process to utilize a larger longitudinal phase space area (approx. = 1 eV sec/bunch vs less than or equal to 0.6 eV sec with H + operation). The resulting reduction in relative longitudinal density partially offsets the increase in space charge effects at higher currents. In order to make the capture process independent of injected beam current, a dynamic beam loading compensation loop was installed on the AGS rf system. This is the only addition to the synchrotron itself that was required to reach the new intensity records. A discussion of injection, the rf capture process, and space charge effects is presented. 9 refs., 5 figs

Financial remuneration for clinical and behavioral research participation: ethical and practical considerations.

Science.gov (United States)

Permuth-Wey, Jennifer; Borenstein, Amy R

2009-04-01

Although the practice of providing payment to clinical research participants has been ongoing for more than a century, it remains an ethically controversial topic among members of the research community. The aims of this commentary are to summarize ethical and practical considerations regarding financial remuneration of research participants and to make recommendations for researchers contemplating this practice. A PubMed search was conducted to explore the ethical implications surrounding financial remuneration and review the body of empiric data on this topic. Financial remuneration is perceived to be ethically acceptable by many researchers and research participants and can be helpful in the recruitment process. It is recommended that when investigators are contemplating whether to offer payment to research participants, they should consider the nature of the study and the potential benefits and risks to the participants, institutional or organizational guidelines, and cultural and societal norms specific to the population being studied. Financial remuneration has the ability to serve as a sign of appreciation for the contributions of research participants and a way to facilitate clinical and behavioral research.

Summary update of the Brookhaven tritium toxicity program with emphasis on recent cytogenetic and lifetime-shortening studies

International Nuclear Information System (INIS)

Carsten, A.L.; Benz, R.D.; Hughes, W.P.; Ichimasa, Yusuke; Ikushima, Takaji; Tezuka, Hideo.

1988-01-01

A number of years ago a multiparameter program to evaluate the toxicity of tritiated water (HTO) was undertaken in the Medical Department at Brookhaven National Laboratory. The results of most of these studies have been published and will receive brief attention. Emphasis will be placed on the unpublished studies involving the induction of sister chromatid exchanges (SCE's) in bone marrow of mice, new biochemical information, and preliminary results on lifetime-shortening and carcinogenesis. In brief, male Hale-Stoner Brookhaven (HSB) mice maintained on HTO concentrations ranging from 3.0 to 30.0 μCi/ml exhibited essentially the same number of SCE's per cell throughout their lifetime. Control mice showed a decrease in number of SCE's with age. The lack of a dose-response effect and the constant level of SCE's in HTO mice as compared to controls will be discussed. In the carcinogenesis study C57BL/6J male mice received various x-ray or HTO regimens. Mortality data from these and other studies in which CBA/Ca/BNL mice received single x-ray exposures or equivalent integrated dose exposures by single HTO injections will be discussed. 25 refs., 4 figs

Final environmental impact statement. Proton--Proton Storage Accelerator Facility (ISABELLE), Brookhaven National Laboratory, Upton, New York

International Nuclear Information System (INIS)

1978-08-01

An Environmental Impact Statement for a proposed research facility (ISABELLE) to be built at Brookhaven National Laboratory (BNL) is presented. It was prepared by the Department of Energy (DOE) following guidelines issued for such analyses. In keeping with DOE policy, this statement presents a concise and issues-oriented analysis of the significant environmental effects associated with the proposed action. ISABELLE is a proposed physics research facility where beams of protons collide providing opportunities to study high energy interactions. The facility would provide two interlaced storage ring proton accelerators, each with an energy up to 400 GeV intersecting in six experimental areas. The rings are contained in a tunnel with a circumference of 3.8 km (2.3 mi). The facility will occupy 250 ha (625 acres) in the NW corner of the existing BNL site. A draft Environmental Impact Statement for this proposed facility was issued for public review and comment by DOE on February 21, 1978. The principal areas of concern expressed were in the areas of radiological impacts and preservation of cultural values. After consideration of these comments, appropriate actions were taken and the text of the statement has been amended to reflect the comments. The text was annotated to indicate the origin of the comment. The Appendices contain a glossary of terms and listings of metric prefixes and conversions and symbols and abbreviations

Applications of nuclear techniques for in vivo body composition studies at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Cohn, S.H.; Ellis, K.J.; Vartsky, D.; Vaswani, A.N.; Wielopolski, L.

1981-01-01

A series of technical developments and their clinical applications in various nuclear technologies at Brookhaven National Laboratory is described. These include the development of a portable neutron activation facility for measuring cadmium in vivo in kidney and liver, a technique for the measurement of body iron utilizing nuclear resonant scattering of gamma rays, a non-invasive measure of the skeletal levels of lead by an x-ray fluorescence technique, and the development of a pulsed Van de Graaff generator as a source of pulsed neutrons for the measurement of lung silicon

Applications of nuclear techniques for in vivo body composition studies at Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Cohn, S.H.; Ellis, K.J.; Vartsky, D.; Vaswani, A.N.; Wielopolski, L.

1981-01-01

A series of technical developments and their clinical applications in various nuclear technologies at Brookhaven National Laboratory is described. These include the development of a portable neutron activation facility for measuring cadmium in vivo in kidney and liver, a technique for the measurement of body iron utilizing nuclear resonant scattering of gamma rays, a non-invasive measure of the skeletal levels of lead by an x-ray fluorescence technique, and the development of a pulsed Van de Graaff generator as a source of pulsed neutrons for the measurement of lung silicon. (ACR)

Corrosion analysis of decommissioned carbon steel waste water tanks at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Soo, P.; Roberts, T.C.

1995-07-01

A corrosion analysis was carried out on available sections of carbon steels taken from two decommissioned radioactive waste water tanks at Brookhaven National Laboratory. One of the 100,000 gallon tanks suffered from a pinhole failure in the wall which was subsequently patched. From the analysis it was shown that this leak, and two adjacent leaks were initiated by a discarded copper heating coil that had been dropped into the tank during service. The failure mechanism is postulated to have been galvanic attack at points of contact between the tank structure and the coil. Other leaks in the two tanks are also described in this report

Specialty Practice and Cost Considerations in the Management of Uveitis Associated With Juvenile Idiopathic Arthritis.

Science.gov (United States)

Palestine, Alan G; Singh, Jasleen K; Kolfenbach, Jason R; Ozzello, Daniel J

2016-07-01

To evaluate whether cost, prior insurance authorization concerns, and subspecialty practice influence therapeutic decisions in the treatment of uveitis associated with juvenile idiopathic arthritis. A total of 2,965 pediatric ophthalmologists, uveitis specialists, retina specialists, and rheumatologists across the United States were surveyed via e-mail regarding their choice in long-term therapy for a hypothetical patient with uveitis associated with juvenile idiopathic arthritis. Outcomes of interest were differences in therapy choice based on cost/prior authorization and specialty practice. There were significant differences in the use of methotrexate and biologics among specialists, both with and without consideration for cost and prior authorization. Physicians in four different specialties who treat uveitis associated with juvenile idiopathic arthritis agree on methotrexate as a first-line treatment choice and a biologic immunosuppressive medication as a second choice, but there are significant differences between the specialties in their use of these medications. Cost and insurance considerations did not affect therapy selection. [J Pediatr Ophthalmol Strabismus. 2016;53(4):246-251.]. Copyright 2016, SLACK Incorporated.

MO-E-BRC-00: Online Adaptive Radiotherapy - Considerations for Practical Clinical Implementation

International Nuclear Information System (INIS)

2016-01-01

Online adaptive radiation therapy has the potential to ensure delivery of optimal treatment to the patient by accounting for anatomical and potentially functional changes that occur from one fraction to the next and over the course of treatment. While on-line adaptive RT (ART) has been a topic of many publications, discussions, and research, it has until very recently remained largely a concept and not a practical implementation. However, recent advances in on-table imaging, use of deformable image registration for contour generation and dose tracking, faster and more efficient plan optimization, as well as fast quality assurance method has enabled the implementation of ART in the clinic in the past couple of years. The introduction of these tools into routine clinical use requires many considerations and progressive knowledge to understand how processes that have historically taken hours/days to complete can now be done in less than 30 minutes. This session will discuss considerations to perform real time contouring, planning and patient specific QA, as well as a practical workflow and the required resources. Learning Objectives: To understand the difficulties, challenges and available technologies for online adaptive RT. To understand how to implement online adaptive therapy in a clinical environment and to understand the workflow and resources required. To understand the limitations and sources of uncertainty in the online adaptive process I have research funding from ViewRay Inc. and Philips Medical Systems.; R. Kashani, I have research funding from ViewRay Inc. and Philips Medical Systems.; X. Li, Research supported by Elekta Inc.

MO-E-BRC-00: Online Adaptive Radiotherapy - Considerations for Practical Clinical Implementation

Energy Technology Data Exchange (ETDEWEB)

NONE

2016-06-15

Online adaptive radiation therapy has the potential to ensure delivery of optimal treatment to the patient by accounting for anatomical and potentially functional changes that occur from one fraction to the next and over the course of treatment. While on-line adaptive RT (ART) has been a topic of many publications, discussions, and research, it has until very recently remained largely a concept and not a practical implementation. However, recent advances in on-table imaging, use of deformable image registration for contour generation and dose tracking, faster and more efficient plan optimization, as well as fast quality assurance method has enabled the implementation of ART in the clinic in the past couple of years. The introduction of these tools into routine clinical use requires many considerations and progressive knowledge to understand how processes that have historically taken hours/days to complete can now be done in less than 30 minutes. This session will discuss considerations to perform real time contouring, planning and patient specific QA, as well as a practical workflow and the required resources. Learning Objectives: To understand the difficulties, challenges and available technologies for online adaptive RT. To understand how to implement online adaptive therapy in a clinical environment and to understand the workflow and resources required. To understand the limitations and sources of uncertainty in the online adaptive process I have research funding from ViewRay Inc. and Philips Medical Systems.; R. Kashani, I have research funding from ViewRay Inc. and Philips Medical Systems.; X. Li, Research supported by Elekta Inc.

Ion Sources, Preinjectors and the Road to EBIS (459th Brookhaven Lecture)

International Nuclear Information System (INIS)

Alessi, James

2010-01-01

To meet the requirements of the scientific programs of the Relativistic Heavy Ion Collider and the NASA Space Radiation Lab, BNL's Collider-Accelerator Department needs a variety of ion sources. Although these sources are a relatively small and inexpensive part of an accelerator, they can have a big impact on the machine's overall performance. For the 459th Brookhaven Lecture, James Alessi will describe C-AD's long history of developing state-of-the-art ion sources for its accelerators, and its current process for source and pre-injector development. He will follow up with a discussion of the features and development status of EBIS, which, as the newest source and preinjector, is in the final stages of commissioning at the end of a five-year construction project.

Summary update of the Brookhaven tritium toxicity program with emphasis on recent cytogenetic and lifetime-shortening studies

Energy Technology Data Exchange (ETDEWEB)

Carsten, A.L.; Benz, R.D.; Hughes, W.P.; Ichimasa, Yusuke; Ikushima, Takaji; Tezuka, Hideo

1988-01-01

A number of years ago a multiparameter program to evaluate the toxicity of tritiated water (HTO) was undertaken in the Medical Department at Brookhaven National Laboratory. The results of most of these studies have been published and will receive brief attention. Emphasis will be placed on the unpublished studies involving the induction of sister chromatid exchanges (SCE's) in bone marrow of mice, new biochemical information, and preliminary results on lifetime-shortening and carcinogenesis. In brief, male Hale-Stoner Brookhaven (HSB) mice maintained on HTO concentrations ranging from 3.0 to 30.0 ..mu..Ci/ml exhibited essentially the same number of SCE's per cell throughout their lifetime. Control mice showed a decrease in number of SCE's with age. The lack of a dose-response effect and the constant level of SCE's in HTO mice as compared to controls will be discussed. In the carcinogenesis study C57BL/6J male mice received various x-ray or HTO regimens. Mortality data from these and other studies in which CBA/Ca/BNL mice received single x-ray exposures or equivalent integrated dose exposures by single HTO injections will be discussed. 25 refs., 4 figs.

On some practical consideration of the electron beam breakup transit time oscillator

International Nuclear Information System (INIS)

Kwan, T.J.T.

1992-01-01

The electron beam breakup transit time oscillator (BTO) makes use of the interaction between an electron beam and the azimuthally azimuthally asymmetric transverse magnetic mode (TM 110 ) of a cavity to facilitate the exchange of energy between them. Linear theory has shown a large growth rate in the regime where space-charge effects can be ignored. In this study, we have investigated the non-ideal elements in the BTO and evaluated their effects accordingly. The practical issues under consideration are electron beam quality, energy, and space-charge potential. Our calculations indicate only a modest unfavorable scalings with respect to these parameters

HOM identification by bead pulling in the Brookhaven ERL cavity

CERN Document Server

Hahn, H; Jain, Puneet; Johnson, Elliott C; Xu, Wencan

2014-01-01

Exploratory measurements of the Brookhaven Energy Recovery Linac (ERL) cavity at superconducting temperature produced a long list of high order modes (HOMs). The niobium 5-cell cavity is terminated at each end with HOM ferrite dampers that successfully reduce the Q-factors to levels required to avoid beam break up (BBU) instabilities. However, a number of un-damped resonances with Q≥106 were found at 4 K and their mode identification forms the focus of this paper. The approach taken here consists of bead pulling on a copper (Cu) replica of the ERL cavity with dampers involving various network analyzer measurements. Several different S21 transmission measurements are used, including those taken from the fundamental input coupler to the pick-up probe across the cavity, others between beam-position monitor probes in the beam tubes, and also between probes placed into the cells. The bead pull technique suitable for HOM identification with a metallic needle or dielectric bead is detailed. This paper presents the...

Nurse and midwifery prescribing in Ireland: A scope-of-practice development for worldwide consideration.

Science.gov (United States)

Wilson, Donna M; Murphy, Jill; Nam, Mavis A; Fahy, Anne; Tella, Susanna

2018-01-29

For 10 years, select Irish nurses and midwives who pass a rigorous 6 month theory and practical program can prescribe medications and other medicinal products. Given the need for timely, accessible, and affordable health-care services in all countries, this nursing/midwifery education and practice development is worthy of examination. Irish nurse/midwife prescribing occurred following long-term deliberative nursing profession advocacy, nursing education planning, nursing administration and practice planning, interdisciplinary health-care team support and complementary efforts, and government action. A review of documents, research, and other articles was undertaken to examine this development process and report evaluative information for consideration by other countries seeking to improve their health-care systems. Nurse/midwife prescribing was accomplished successfully in Ireland, with the steps taken there to initiate and establish nurse/midwife prescribing of value internationally. © 2018 John Wiley & Sons Australia, Ltd.

Brookhaven highlights, October 1978-September 1979. [October 1978 to September 1979

Energy Technology Data Exchange (ETDEWEB)

1979-01-01

These highlights present an overview of the major research and development achievements at Brookhaven National Laboratory from October 1978 to September 1979. Specific areas covered include: accelerator and high energy physics programs; high energy physics research; the AGS and improvements to the AGS; neutral beam development; heavy ion fusion; superconducting power cables; ISABELLE storage rings; the BNL Tandem accelerator; heavy ion experiments at the Tandem; the High Flux Beam Reactor; medium energy physics; nuclear theory; atomic and applied physics; solid state physics; neutron scattering studies; x-ray scattering studies; solid state theory; defects and disorder in solids; surface physics; the National Synchrotron Light Source ; Chemistry Department; Biology Department; Medical Department; energy sciences; environmental sciences; energy technology programs; National Center for Analysis of Energy Systems; advanced reactor systems; nuclear safety; National Nuclear Data Center; nuclear materials safeguards; Applied Mathematics Department; and support activities. (GHT)

RHIC: What We Have Learned So Far (434th Brookhaven Lecture)

International Nuclear Information System (INIS)

O'Brien, Edward

2008-01-01

One of the world's premiere nuclear research facilities, the Relativistic Heavy Ion Collider (RHIC) at Brookhaven Lab is just completing its eighth year of physics operation. During the past eight years, RHIC's primary physics program has emphasized the creation, observation and explanation of nuclear matter created at temperatures and densities that last existed in the universe some 13.7 billion years ago. RHIC was built to study the strong force, which holds quarks and gluons together within the nucleus of an atom, with the goal of observing a plasma of quarks and gluons freed from the atomic nucleus. The new state of matter that was created, however, was quite different. Dr. O'Brien will discuss what RHIC scientists expected versus what they discovered, and how this finding both challenges existing theory and provides an opportunity to understand the strong force better.

Irvine-Michigan-Brookhaven (I.M.B.) nucleon decay search status report

International Nuclear Information System (INIS)

Bratton, C.B.; Gajewski, W.; Kropp, W.R.

1981-01-01

The Irvine-Michigan-Brookhaven collaboration is currently constructing a 8700 tonne water Cerenkov detector to measure, or establish a lower limit to, the nucleon lifetime. The detector, which should be complete by the middle of October, is located at a depth of 1670 m.w.e. in the Morton Salt Mine near Cleveland, Ohio. Activities during the past year have been dominated by the construction of the laboratory and of the phototube, electronic and software systems. In house tests of the phototubes and data acquisition chain have demonstrated their reliability, the feasibility of on-line rejection of cosmic ray muons, and have yielded information relevant to off-line methods of event reconstruction. This report will concentrate on these activities and point out where actual experience or measurement has confirmed or modified features of the proposed detector as described previously in several articles

Practical considerations in voltage stability assessment

Energy Technology Data Exchange (ETDEWEB)

Kundur, P; Gao, B [Powertech Labs. Inc., Surrey, BC (Canada)

1994-12-31

This paper deals with some of the most important practical issues related to voltage stability assessment of large practical systems. A brief discussion of the practical aspects of voltage stability problem and prevention of voltage instability is given first, followed by descriptions of different analytical techniques and tools for voltage stability analysis. Presentations of analytical tools is focused on the VSTAB program which incorporates the modal analysis, continuation power flow, and shortest distance to instability techniques, Finally, an example case study of a practical large system is presented. The case study illustrates how modal analysis is used to determine the most effective load shedding scheme for preventing voltage instability. (author) 15 refs., 2 figs., 2 tabs.

Aerial radiological survey of the Brookhaven National Laboratory and surrounding area, May 1980

International Nuclear Information System (INIS)

Hobaugh, J.L.; Steiner, P.A.

1984-01-01

An aerial radiological survey was performed from 15 to 18 May 1980 over approximately a 21-square-kilometer (8-square-mile) area surrounding the Brookhaven National Laboratory (BNL). BNL is located in the center of Suffolk County, Long Island, New York. All gamma radiation data were collected by flying north-south lines spaced 91 meters (300 feet) apart at an altitude of 61 meters (200 feet) above ground level. A total of 17 anomalous areas were identified. The dominant isotopes found over these areas were cesium-137, manganese-54, and cobalt-60. All anomalies identified by the aerial measurements were correlated to site activities and storage facilities. 4 references, 18 figures, 1 table

Building the Nonuniversity, Tertiary Care Center Hepatobiliary and Pancreatic Surgery Practice: Structural and Financial Considerations.

Science.gov (United States)

Baker, Erin H; Siddiqui, Imran; Vrochides, Dionisios; Iannitti, David A; Martinie, John B; Rorabaugh, Lauren; Jeyarajah, D Rohan; Swan, Ryan Z

2016-12-01

Early in their careers, many new surgeons lack the background and experience to understand essential components needed to build a surgical practice. Surgical resident education is often devoid of specific instruction on the business of medicine and practice management. In particular, hepatobiliary and pancreatic (HPB) surgeons require many key components to build a successful practice secondary to significant interdisciplinary coordination and a scope of complex surgery, which spans challenging benign and malignant disease processes. In the following, we describe the required clinical and financial components for developing a successful HPB surgery practice in the nonuniversity tertiary care center. We discuss significant financial considerations for understanding community need and hospital investment, contract establishment, billing, and coding. We summarize the structural elements and key personnel necessary for establishing an effectual HPB surgical team. This article provides useful, essential information for a new HPB surgeon looking to establish a surgical practice. It also provides insight for health-care administrators as to the value an HPB surgeon can bring to a hospital or health-care system.

17 CFR 201.401 - Consideration of stays.

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Consideration of stays. 201... PRACTICE Rules of Practice Appeal to the Commission and Commission Review § 201.401 Consideration of stays... consideration. Where the action complained of has already taken effect and the motion for stay is filed within...

Department of Energy’s ARM Climate Research Facility External Data Center Operations Plan Located At Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Cialella, A. [Brookhaven National Lab. (BNL), Upton, NY (United States); Gregory, L. [Brookhaven National Lab. (BNL), Upton, NY (United States); Lazar, K. [Brookhaven National Lab. (BNL), Upton, NY (United States); Liang, M. [Brookhaven National Lab. (BNL), Upton, NY (United States); Ma, L. [Brookhaven National Lab. (BNL), Upton, NY (United States); Tilp, A. [Brookhaven National Lab. (BNL), Upton, NY (United States); Wagener, R. [Brookhaven National Lab. (BNL), Upton, NY (United States)

2015-05-01

The External Data Center (XDC) Operations Plan describes the activities performed to manage the XDC, located at Brookhaven National Laboratory (BNL), for the Department of Energy’s Atmospheric Radiation Measurement (ARM) Climate Research Facility. It includes all ARM infrastructure activities performed by the Data Management and Software Engineering Group (DMSE) at BNL. This plan establishes a baseline of expectation within the ARM Operations Management for the group managing the XDC.

Structural biology facilities at Brookhaven National Laboratory`s high flux beam reactor

Energy Technology Data Exchange (ETDEWEB)

Korszun, Z.R.; Saxena, A.M.; Schneider, D.K. [Brookhaven National Laboratory, Upton, NY (United States)

1994-12-31

The techniques for determining the structure of biological molecules and larger biological assemblies depend on the extent of order in the particular system. At the High Flux Beam Reactor at the Brookhaven National Laboratory, the Biology Department operates three beam lines dedicated to biological structure studies. These beam lines span the resolution range from approximately 700{Angstrom} to approximately 1.5{Angstrom} and are designed to perform structural studies on a wide range of biological systems. Beam line H3A is dedicated to single crystal diffraction studies of macromolecules, while beam line H3B is designed to study diffraction from partially ordered systems such as biological membranes. Beam line H9B is located on the cold source and is designed for small angle scattering experiments on oligomeric biological systems.

Highway accident involving radiopharmaceuticals near Brookhaven, Mississippi on December 3, 1983

International Nuclear Information System (INIS)

Mohr, P.B.; Mount, M.E.; Schwartz, M.W.

1985-04-01

A rear-end collision occurred between a passenger automobile and a luggage trailer carrying 84 packages, 76 of which contained radiopharmaceuticals, on US Highway 84 near Brookhaven, Mississippi on the afternoon of December 3, 1983. The purpose of this report is to document the mechanical circumstances of the accident, confirm the nature and quantity of radioactive materials involved, and assess the nature of the physical environment to which the packages were exposed and the response of the packages. The report consists of three major sections. The first deals wth the nature and circumstances of the accident and findings of fact. The second gives an accounting and description of the materials involved and the consequences of their exposure. The third gives an assessment and analysis of the mechanisms of damage and the conclusions which may be drawn from the investigation. 4 refs., 24 figs., 4 tabs

In vivo neutron activation facility at Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Ma, R.; Yasumura, Seiichi; Dilmanian, F.A.

1997-11-01

Seven important body elements, C, N, Ca, P, K, Na, and Cl, can be measured with great precision and accuracy in the in vivo neutron activation facilities at Brookhaven National Laboratory. The facilities include the delayed-gamma neutron activation, the prompt-gamma neutron activation, and the inelastic neutron scattering systems. In conjunction with measurements of total body water by the tritiated-water dilution method several body compartments can be defined from the contents of these elements, also with high precision. In particular, body fat mass is derived from total body carbon together with total body calcium and nitrogen; body protein mass is derived from total body nitrogen; extracellular fluid volume is derived from total body sodium and chlorine; lean body mass and body cell mass are derived from total body potassium; and, skeletal mass is derived from total body calcium. Thus, we suggest that neutron activation analysis may be valuable for calibrating some of the instruments routinely used in clinical studies of body composition. The instruments that would benefit from absolute calibration against neutron activation analysis are bioelectric impedance analysis, infrared interactance, transmission ultrasound, and dual energy x-ray/photon absorptiometry.

In-situ containment of buried waste at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Dwyer, B.P.; Heiser, J.; Stewart, W.; Phillips, S.

1997-01-01

The primary objective of this project was to further develop close-coupled barrier technology for the containment of subsurface waste or contaminant migration. A close-coupled barrier is produced by first installing a conventional cement grout curtain followed by a thin inner lining of a polymer grout. The resultant barrier is a cement polymer composite that has economic benefits derived from the cement and performance benefits from the durable and chemically resistant polymer layer. The technology has matured from a regulatory investigation of issues concerning barriers and barrier materials to a pilot-scale, multiple individual column injections at Sandia National Labs (SNL) to full scale demonstration. The feasibility of this barrier concept was successfully proven in a full scale 'cold test' demonstration at Hanford, WA. Consequently, a full scale deployment of the technology was conducted at an actual environmental restoration site at Brookhaven National Lab (BNL), Long Island, NY. This paper discusses the installation and performance of a technology deployment implemented at OU-1 an Environmental Restoration Site located at BNL

Rebuilding the Brookhaven high flux beam reactor: A feasibility study

International Nuclear Information System (INIS)

Brynda, W.J.; Passell, L.; Rorer, D.C.

1995-01-01

After nearly thirty years of operation, Brookhaven's High Flux Beam Reactor (HFBR) is still one of the world's premier steady-state neutron sources. A major center for condensed matter studies, it currently supports fifteen separate beamlines conducting research in fields as diverse as crystallography, solid-state, nuclear and surface physics, polymer physics and structural biology and will very likely be able to do so for perhaps another decade. But beyond that point the HFBR will be running on borrowed time. Unless appropriate remedial action is taken, progressive radiation-induced embrittlement problems will eventually shut it down. Recognizing the HFBR's value as a national scientific resource, members of the Laboratory's scientific and reactor operations staffs began earlier this year to consider what could be done both to extend its useful life and to assure that it continues to provide state-of-the-art research facilities for the scientific community. This report summarizes the findings of that study. It addresses two basic issues: (i) identification and replacement of lifetime-limiting components and (ii) modifications and additions that could expand and enhance the reactor's research capabilities

The program of the ALARA Center at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Khan, T.A.; Baum, J.W.

1993-01-01

In 1984 the Brookhaven National Laboratory was asked by the Nuclear Regulatory Commission to set up a Center to monitor dose-reduction efforts in the US and abroad and to focus the industry's attention on ALARA. The paper summarizes the main work of the ALARA Center between 1984 and 1992. The Center maintains nine data bases for the NRC and the Nuclear Power Industry. These databases are constantly updated and access to them is provided through a personal computer and a modem and by periodic publications in the form of a newsletter and NUREG reports. Also described briefly are eight other projects related to dose-reduction at nuclear power plants that the Center has carried out for the NRC. Among these are projects that analyze the cost-effectiveness of engineering modifications, look at worldwide activities at dose reduction and compare US and foreign dose experience, examine high-dose worker groups and high-dose jobs, develop optimum techniques to control contamination at nuclear plants, and look at the doses being received by men and women in all sectors of the nuclear industry

Seismic upgrading of the Brookhaven High Flux Beam Research Reactor

International Nuclear Information System (INIS)

Subudhi, M.

1985-01-01

In recent years the High Flux Beam Research (HFBR) reactor facility at Brookhaven National Laboratory (BNL) was upgraded from 40 to 50 MW power level. The reactor plant was built in the early sixties to the seismic design requirements of the period, using the static load approach. While the plant power level was upgraded, the seismic design was also improved according to current design criteria. This included the development of new floor response spectra for the facility and an overall seismic analysis of those systems important to the safe shutdown of the reactor. Items included in the reanalysis are the containment building with its internal structure, the piping systems, tanks, equipment, and heat exchangers. This paper describes the procedure utilized in developing the floor response spectra for the existing facility. Also included in the paper are the findings and recommendations, based on the seismic analysis, regarding the seismic adequacy of structural and mechanical systems vital to achieving the safe shutdown of the reactor. 11 references, 4 figures, 1 table

Practical Considerations for Clinical PET/MR Imaging.

Science.gov (United States)

Galgano, Samuel; Viets, Zachary; Fowler, Kathryn; Gore, Lael; Thomas, John V; McNamara, Michelle; McConathy, Jonathan

2018-01-01

Clinical PET/MR imaging is currently performed at a number of centers around the world as part of routine standard of care. This article focuses on issues and considerations for a clinical PET/MR imaging program, focusing on routine standard-of-care studies. Although local factors influence how clinical PET/MR imaging is implemented, the approaches and considerations described here intend to apply to most clinical programs. PET/MR imaging provides many more options than PET/computed tomography with diagnostic advantages for certain clinical applications but with added complexity. A recurring theme is matching the PET/MR imaging protocol to the clinical application to balance diagnostic accuracy with efficiency. Copyright © 2017 Elsevier Inc. All rights reserved.

Addressing the paradox of the team innovation process: A review and practical considerations.

Science.gov (United States)

Thayer, Amanda L; Petruzzelli, Alexandra; McClurg, Caitlin E

2018-01-01

Facilitating team innovation is paramount to promoting progress in the science, technology, engineering, and math fields, as well as advancing national health, safety, prosperity, and welfare. However, innovation teams face a unique set of challenges due to the novelty and uncertainty that is core to the definition of innovation, as well as the paradoxical nature of idea generation and idea implementation processes. These and other challenges must be overcome for innovation teams to realize their full potential for producing change. The purpose of this review is, thus, to provide insight into the unique context that these teams function within and provide an integrative, evidence-based, and practically useful, organizing heuristic that focuses on the most important considerations for facilitating team innovation. Finally, we provide practical guidance for psychologists, organizations, practitioners, scientists, educators, policymakers, and others who employ teams to produce novel, innovative solutions to today's problems. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Omalizumab: Practical considerations regarding the risk of anaphylaxis

Directory of Open Access Journals (Sweden)

Kim Harold L

2010-12-01

Full Text Available Abstract Omalizumab has demonstrated efficacy among patients with moderate to severe persistent allergic asthma, whose symptoms are inadequately controlled with other controller agents. This therapy is generally well tolerated, but there are some safety considerations, the most important of which is the rare, but potentially life-threatening, occurrence of omalizumab-associated anaphylaxis. In Canada, data from the manufacturer of omalizumab indicate that the frequency of anaphylaxis attributed to Xolair in post-marketing use is approximately 0.2%. Other researchers, including the American Omalizumab Joint Task Force (OJTF, have suggested a lower overall frequency of 0.09%. This paper provides a summary of the epidemiologic research carried out to date and presents a concise, practical set of recommendations for the prevention, monitoring and management of omalizumab-associated anaphylaxis. Prevention tips include advice on patient education measures, concomitant medications and optimal administration. For the first three injections, the recommendation is to monitor in clinic for two hours after the omalizumab injection; for subsequent injections, the monitoring period should be 30 minutes or an appropriate time agreed upon by the individual patient and healthcare professional. In the event that a patient does experience omalizumab-associated anaphylaxis, the paper provides recommendations for handling the situation in-clinic and recommendations on how to counsel patients to recognize the potential signs and symptoms in the community and react appropriately.

Consideration of children with intellectual disability as candidates for solid organ transplantation-A practice in evolution.

Science.gov (United States)

Wightman, Aaron; Diekema, Douglas; Goldberg, Aviva

2018-02-01

Children with intellectual disability were historically excluded from consideration as recipients of solid organ transplants. In light of an evolution in provider practices, this commentary will define intellectual disability and review the relevant provider attitudes and guidelines and known outcomes of solid organ transplant in this population. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Brookhaven highlights. [Fiscal year 1992, October 1, 1991--September 30, 1992

Energy Technology Data Exchange (ETDEWEB)

Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L. [eds.

1992-12-31

This publication provides a broad overview of the research programs and efforts being conducted, built, designed, and planned at Brookhaven National Laboratory. This work covers a broad range of scientific disciplines. Major facilities include the Alternating Gradient Synchrotron (AGS), with its newly completed booster, the National Synchrotron Light Source (NSLS), the High Flux Beam Reactor (HFBR), and the RHIC, which is under construction. Departments within the laboratory include the AGS department, accelerator development, physics, chemistry, biology, NSLS, medical, nuclear energy, and interdepartmental research efforts. Research ranges from the pure sciences, in nuclear physics and high energy physics as one example, to environmental work in applied science to study climatic effects, from efforts in biology which are a component of the human genome project to the study, production, and characterization of new materials. The paper provides an overview of the laboratory operations during 1992, including staffing, research, honors, funding, and general laboratory plans for the future.

Articles on Practical Cybernetics. Computer-Developed Computers; Heuristics and Modern Sciences; Linguistics and Practice; Cybernetics and Moral-Ethical Considerations; and Men and Machines at the Chessboard.

Science.gov (United States)

Berg, A. I.; And Others

Five articles which were selected from a Russian language book on cybernetics and then translated are presented here. They deal with the topics of: computer-developed computers, heuristics and modern sciences, linguistics and practice, cybernetics and moral-ethical considerations, and computer chess programs. (Author/JY)

Guide to nondestructive assay standards: Preparation criteria, availability, and practical considerations

International Nuclear Information System (INIS)

Stewart, J.E.; Hsue, S.T.; Sampson, T.E.

1997-01-01

For certification and measurement control, nondestructive assay (NDA) instruments and methods used for verification measurement of special nuclear materials (SNMs) require calibrations based on certified reference materials (CRMs), or working reference materials (WRMs), traceable to the national system of measurements, and adequately characteristic of the unknowns. The Department of Energy Office of Safeguards and Security is sponsoring production of a comprehensive guide to preparation of NDA standards. The scope of the report includes preparation criteria, current availability of CRMs and WRMs, practical considerations for preparation and characterization, and an extensive bibliography. In preparing the report, based primarily on experience at Los Alamos, we have found that standards preparation is highly dependent on the particular NDA method being applied. We therefore include sections that contain information specific to commonly used neutron and gamma-ray NDA techniques. 16 refs., 4 figs., 2 tabs

DOE handbook: Design considerations

International Nuclear Information System (INIS)

1999-04-01

The Design Considerations Handbook includes information and suggestions for the design of systems typical to nuclear facilities, information specific to various types of special facilities, and information useful to various design disciplines. The handbook is presented in two parts. Part 1, which addresses design considerations, includes two sections. The first addresses the design of systems typically used in nuclear facilities to control radiation or radioactive materials. Specifically, this part addresses the design of confinement systems and radiation protection and effluent monitoring systems. The second section of Part 1 addresses the design of special facilities (i.e., specific types of nonreactor nuclear facilities). The specific design considerations provided in this section were developed from review of DOE 6430.1A and are supplemented with specific suggestions and considerations from designers with experience designing and operating such facilities. Part 2 of the Design Considerations Handbook describes good practices and design principles that should be considered in specific design disciplines, such as mechanical systems and electrical systems. These good practices are based on specific experiences in the design of nuclear facilities by design engineers with related experience. This part of the Design Considerations Handbook contains five sections, each of which applies to a particular engineering discipline

DOE handbook: Design considerations

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-04-01

The Design Considerations Handbook includes information and suggestions for the design of systems typical to nuclear facilities, information specific to various types of special facilities, and information useful to various design disciplines. The handbook is presented in two parts. Part 1, which addresses design considerations, includes two sections. The first addresses the design of systems typically used in nuclear facilities to control radiation or radioactive materials. Specifically, this part addresses the design of confinement systems and radiation protection and effluent monitoring systems. The second section of Part 1 addresses the design of special facilities (i.e., specific types of nonreactor nuclear facilities). The specific design considerations provided in this section were developed from review of DOE 6430.1A and are supplemented with specific suggestions and considerations from designers with experience designing and operating such facilities. Part 2 of the Design Considerations Handbook describes good practices and design principles that should be considered in specific design disciplines, such as mechanical systems and electrical systems. These good practices are based on specific experiences in the design of nuclear facilities by design engineers with related experience. This part of the Design Considerations Handbook contains five sections, each of which applies to a particular engineering discipline.

Initial experiments with the Nevis Cyclotron, the Brookhaven Cosmotron, the Brookhaven AGS and their effects on high energy physics

International Nuclear Information System (INIS)

Lindenbaum, S.J.

1988-01-01

The first experiment at the Nevis Cyclotron by Bernardini, Booth and Lindenbaum demonstrated that nuclear stars are produced by a nucleon-nucleon cascade within the nucleon. This solved a long standing problem in Cosmic rays and made it clear that where they overlap cosmic ray investigation would not be competitive with accelerator investigations. The initial experiments at the Brookhaven Cosmotron by Lindenbaum and Yuan demonstrated that low energy pion nucleon scattering and pion production were unexpectedly mostly due to excitation of the isotopic spin = angular momentum = 3/2 isobaric state of the nucleon. This contradicted the Fermi statistical theory and led to the Isobar model proposed by the author and a collaborator. The initial experiments at the AGS by the author and collaborators demonstrated that the Pomeronchuck Theorem would not come true till at least several hundred GeV. These scattering experiments led to the development of the ''On-line Computer Technique'' by the author and collaborators which is now the almost universal technique in high energy physics. The first accomplishment which flowed from this technique led to contradiction of the Regge pole theory as a dynamical asymptotic theory, by the author and collaborators. The first critical experimental proof of the forward dispersion relation in strong interactions was accomplished by the author and collaborators. They were then used as a crystal ball to predict that ''Asymptopia''---the theoretically promised land where all asymptotic theorems come true---would not be reached till at least 25,000 BeV and probably not before 1,000,000 BeV. 26 refs., 11 figs., 2 tabs

Summary of proposed approach for deriving cleanup guidelines for radionuclides in soil at Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Meinhold, A.F.; Morris, S.C.; Dionne, B.; Moskowitz, P.D.

1996-11-01

Past activities at Brookhaven National Laboratory (BNL) resulted in soil and groundwater contamination. As a result, BNL was designated a Superfund site under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA). BNL`s Office of Environmental Restoration (OER) is overseeing environmental restoration activities at the Laboratory, carried out under an Interagency Agreement (IAG) with the United States Department of Energy (DOE), the United States Environmental Protection Agency (EPA) and the New York State Department of Environmental Conservation (NYSDEC). The objective of this paper is to propose a standard approach to deriving risk-based cleanup guidelines for radionuclides in soil at BNL.

Summary of proposed approach for deriving cleanup guidelines for radionuclides in soil at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Meinhold, A.F.; Morris, S.C.; Dionne, B.; Moskowitz, P.D.

1996-11-01

Past activities at Brookhaven National Laboratory (BNL) resulted in soil and groundwater contamination. As a result, BNL was designated a Superfund site under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA). BNL's Office of Environmental Restoration (OER) is overseeing environmental restoration activities at the Laboratory, carried out under an Interagency Agreement (IAG) with the United States Department of Energy (DOE), the United States Environmental Protection Agency (EPA) and the New York State Department of Environmental Conservation (NYSDEC). The objective of this paper is to propose a standard approach to deriving risk-based cleanup guidelines for radionuclides in soil at BNL

Practical considerations in the development and application of reference levels

International Nuclear Information System (INIS)

Selby, J. M.; Kennedy, W. E. Jr.; Swinth, K. L.; Gilbert, R. O.; Soldat, J. K.

1988-05-01

Radiological exposures to the public during an accident that releases radioactive materials to the environment occur initially through the air pathway, secondly through a water pathway, and finally, through the food chain. From these exposure pathways, reference levels of radionuclides must be applied to limit public radiation doses. Such reference levels are difficult to develop and apply, particularly if the contaminants are transuranic elements such as plutonium. The reference level must be related to a resultant theoretical dose to the public through generic calculations. However, to permit rapid decisions after an accident, the reference levels need to be related to conditions or media in the environment that can be directly measured. They must also be tied to specific countermeasures such as sheltering, evacuation, or interdiction of drinking water or food supplies. This paper discusses the practical considerations in the development and application of reference levels for transuranic in the environment and the present capability to rapidly detect and quantify their concentrations following accidental contamination events. 16 refs., 3 tabs

Guide to nondestructive assay standards: Preparation criteria, availability, and practical considerations

International Nuclear Information System (INIS)

Hsue, S.T.; Stewart, J.E.; Sampson, T.E.; Butler, G.W.; Rudy, C.R.; Rinard, P.M.

1997-10-01

For certification and measurement control, nondestructive assay (NDA) instruments and methods used for verification measurements of special nuclear materials (SNMs) require calibrations based on certified reference materials (CRMs), or working reference materials (WRMs), traceable to the national system of measurements, and adequately characteristic of the unknowns. The Department of Energy Office of Safeguards and Security is sponsoring production of a comprehensive guide to preparation of NDA standards. The scope of the report includes preparation criteria, current availability of CRMs and WRMs, practical considerations for preparation and characterization, and an extensive bibliography. In preparing the report, based primarily on experience at Los Alamos, they have found that standards preparation is highly dependent on the particular NDA method being applied. They therefore include sections that contain information specific to commonly used neutron and gamma-ray NDA techniques. They also present approaches that are alternatives to, or minimize requirements for physical standards

New newtron time-of-flight (NTOF) facilities at the Brookhaven 200-MeV Linac

International Nuclear Information System (INIS)

Ward, T.E.; Alessi, J.; Brennan, J.; Grand, P.; Lankshear, R.; Snead, C.L.; Tsoupas, N.; Zucker, M.

1988-01-01

The installation of a new beam chopper and radio-frequency quadrupole (RFQ) preinjector (750 keV) at the Brookhaven National Laboratory (BNL) 200-MeV Linac will enable single micropulse selection (pulse width 9 pμ pulse with dc-average beam currents of 50 nA-1 μA routinely available. The NTOF facilities consists of 30-100 meter flight paths at angles of 0, 12, 30, 45, 90, and 135/degree/. Lower energies of 93, 117, 139, 161, and 181 MeV are also available as well as polarized beams at much reduced intensities. The present paper describes the new facilities, and the capabilities of future improvements and upgrades, for use in the BNL intermediate energy (p,n) experimental program. 7 refs., 2 figs., 1 tab

Practical aspects of telehealth: financial considerations.

Science.gov (United States)

Loh, P K; Sabesan, S; Allen, D; Caldwell, P; Mozer, R; Komesaroff, P A; Talman, P; Williams, M; Shaheen, N; Grabinski, O; Withnall, D

2013-07-01

The second in a series of articles about the practical aspects of telehealth, this paper includes information and a case history on the cost-benefits for patients and practitioners using telehealth. The case history demonstrates that telehealth can save travel time for patients, carers and specialists, and can reduce out-of-pocket expenses. The practical aspects of telehealth article series considers the contextual, clinical, technical and ethical components of online video consultations. © 2013 The Authors; Internal Medicine Journal © 2013 Royal Australasian College of Physicians.

Relative Binding Free Energy Calculations in Drug Discovery: Recent Advances and Practical Considerations.

Science.gov (United States)

Cournia, Zoe; Allen, Bryce; Sherman, Woody

2017-12-26

Accurate in silico prediction of protein-ligand binding affinities has been a primary objective of structure-based drug design for decades due to the putative value it would bring to the drug discovery process. However, computational methods have historically failed to deliver value in real-world drug discovery applications due to a variety of scientific, technical, and practical challenges. Recently, a family of approaches commonly referred to as relative binding free energy (RBFE) calculations, which rely on physics-based molecular simulations and statistical mechanics, have shown promise in reliably generating accurate predictions in the context of drug discovery projects. This advance arises from accumulating developments in the underlying scientific methods (decades of research on force fields and sampling algorithms) coupled with vast increases in computational resources (graphics processing units and cloud infrastructures). Mounting evidence from retrospective validation studies, blind challenge predictions, and prospective applications suggests that RBFE simulations can now predict the affinity differences for congeneric ligands with sufficient accuracy and throughput to deliver considerable value in hit-to-lead and lead optimization efforts. Here, we present an overview of current RBFE implementations, highlighting recent advances and remaining challenges, along with examples that emphasize practical considerations for obtaining reliable RBFE results. We focus specifically on relative binding free energies because the calculations are less computationally intensive than absolute binding free energy (ABFE) calculations and map directly onto the hit-to-lead and lead optimization processes, where the prediction of relative binding energies between a reference molecule and new ideas (virtual molecules) can be used to prioritize molecules for synthesis. We describe the critical aspects of running RBFE calculations, from both theoretical and applied perspectives

Design of the beryllium window for Brookhaven Linac Isotope Producer

International Nuclear Information System (INIS)

Nayak, S.; Mapes, M.; Raparia, D.

2015-01-01

In the Brookhaven Linac Isotope Producer (BLIP) beam line, there were two Beryllium (Be) windows with an air gap to separate the high vacuum upstream side from low vacuum downstream side. There had been frequent window failures in the past which affected the machine productivity and increased the radiation dose received by workers due to unplanned maintenance. To improve the window life, design of Be window is reexamined. Detailed structural and thermal simulations are carried out on Be window for different design parameters and loading conditions to come up with better design to improve the window life. The new design removed the air gap and connect the both beam lines with a Be window in-between. The new design has multiple advantages such as 1) reduces the beam energy loss (because of one window with no air gap), 2) reduces air activation due to nuclear radiation and 3) increased the machine reliability as there is no direct pressure load during operation. For quick replacement of this window, an aluminum bellow coupled with load binder was designed. There hasn't been a single window failure since the new design was implemented in 2012.

Ethics and values in health care practice: philosophical, educational, and political considerations.

Science.gov (United States)

Carvalho, Vilma de

2011-12-01

This paper presents philosophical, pedagogical and political considerations on Ethics and Values in Professional Health Care Practice. The current changes and crises in the world, intensified by economic turmoil, have affected social justice issues affecting health and education. to clarify nurses' role in the context of the art to take care of clients both as individuals and community; to urge nurses for attention to laws and codes/norms as established in the profession; and to suggest the application of basic laws of the Philosophy of Art to nursing care. The study presents critical analysis on ethics and values involved in nursing actions and may affect the art of learning-to-be and becoming an expert professional in nursing care. The author's epistemological position is presented to build competencies in the nursing as a health science.

Heat leak testing of a superconducting RHIC dipole magnet at Brookhaven National Laboratory

International Nuclear Information System (INIS)

DeLalio, J.T.; Brown, D.P.; Sondericker, J.H.

1993-01-01

Brookhaven National Laboratory is currently performing heat load tests on a superconducting dipole magnet. The magnet is a prototype of the 360, 8 cm bore, arc dipole magnets that will be used in the Relativistic Heavy Ion Collider (RMC). An accurate measurement of the heat load is needed to eliminate cumulative errors when determining the REUC cryogenic system load requirements. The test setup consists of a dipole positioned between two quadrupoles in a common vacuum tank and heat shield. Piping and instrumentation are arranged to facilitate measurement of the heat load on the primary 4.6 K magnet load and the secondary 55 K heat shield load. Initial results suggest that the primary heat load is well below design allowances. The secondary load was found to be higher than estimated, but remained close to the budgeted amount. Overall, the dipole performed to specifications

Using Smartphones to Collect Behavioral Data in Psychological Science: Opportunities, Practical Considerations, and Challenges.

Science.gov (United States)

Harari, Gabriella M; Lane, Nicholas D; Wang, Rui; Crosier, Benjamin S; Campbell, Andrew T; Gosling, Samuel D

2016-11-01

Smartphones now offer the promise of collecting behavioral data unobtrusively, in situ, as it unfolds in the course of daily life. Data can be collected from the onboard sensors and other phone logs embedded in today's off-the-shelf smartphone devices. These data permit fine-grained, continuous collection of people's social interactions (e.g., speaking rates in conversation, size of social groups, calls, and text messages), daily activities (e.g., physical activity and sleep), and mobility patterns (e.g., frequency and duration of time spent at various locations). In this article, we have drawn on the lessons from the first wave of smartphone-sensing research to highlight areas of opportunity for psychological research, present practical considerations for designing smartphone studies, and discuss the ongoing methodological and ethical challenges associated with research in this domain. It is our hope that these practical guidelines will facilitate the use of smartphones as a behavioral observation tool in psychological science. © The Author(s) 2016.

Some practical considerations in finite element-based digital image correlation

KAUST Repository

Wang, Bo

2015-04-20

As an alternative to subset-based digital image correlation (DIC), finite element-based (FE-based) DIC method has gained increasing attention in the experimental mechanics community. However, the literature survey reveals that some important issues have not been well addressed in the published literatures. This work therefore aims to point out a few important considerations in the practical algorithm implementation of the FE-based DIC method, along with simple but effective solutions that can effectively tackle these issues. First, to better accommodate the possible intensity variations of the deformed images practically occurred in real experiments, a robust zero-mean normalized sum of squared difference criterion, instead of the commonly used sum of squared difference criterion, is introduced to quantify the similarity between reference and deformed elements in FE-based DIC. Second, to reduce the bias error induced by image noise and imperfect intensity interpolation, low-pass filtering of the speckle images with a 5×5 pixels Gaussian filter prior to correlation analysis, is presented. Third, to ensure the iterative calculation of FE-based DIC converges correctly and rapidly, an efficient subset-based DIC method, instead of simple integer-pixel displacement searching, is used to provide accurate initial guess of deformation for each calculation point. Also, the effects of various convergence criteria on the efficiency and accuracy of FE-based DIC are carefully examined, and a proper convergence criterion is recommended. The efficacy of these solutions is verified by numerical and real experiments. The results reveal that the improved FE-based DIC offers evident advantages over existing FE-based DIC method in terms of accuracy and efficiency. © 2015 Elsevier Ltd. All rights reserved.

Practical considerations in the development of hemoglobin-based oxygen therapeutics.

Science.gov (United States)

Kim, Hae Won; Estep, Timothy N

2012-09-01

The development of hemoglobin based oxygen therapeutics (HBOCs) requires consideration of a number of factors. While the enabling technology derives from fundamental research on protein biochemistry and biological interactions, translation of these research insights into usable medical therapeutics demands the application of considerable technical expertise and consideration and reconciliation of a myriad of manufacturing, medical, and regulatory requirements. The HBOC development challenge is further exacerbated by the extremely high intravenous doses required for many of the indications contemplated for these products, which in turn implies an extremely high level of purity is required. This communication discusses several of the important product configuration and developmental considerations that impact the translation of fundamental research discoveries on HBOCs into usable medical therapeutics.

Practical and clinical considerations in Cobalt-60 tomotherapy

Directory of Open Access Journals (Sweden)

Joshi Chandra

2009-01-01

Full Text Available Cobalt-60 (Co-60 based radiation therapy continues to play a significant role in not only developing countries, where access to radiation therapy is extremely limited, but also in industrialized countries. Howver, technology has to be developed to accommodate modern techniques, in-clud-ing image guided and adaptive radiation therapy (IGART. In this paper we describe some of the practical and clinical considerations for Co-60 based tomotherapy by comparing Co-60 and 6 MV linac-based tomotherapy plans for a head and neck (HandN cancer and a prostate cancer case. The tomotherapy IMRT plans were obtained by modeling a MIMiC binary multi-leaf collimator attached to a Theratron-780c Co-60 unit and a 6 MV linear accelerator (CL2100EX. The EGSnrc/BEAMnrc Monte Carlo (MC code was used for the modeling of the treatment units with the MIMiC collimator and EGSnrc/DOSXYZnrc code was used for beamlet dose data. An in-house inverse treatment planning program was then used to generate optimized tomotherapy dose distributions for the H and N and prostate cases. The dose distributions, cumulative dose area histograms (DAHs and dose difference maps were used to evaluate and compare Co-60 and 6 MV based tomotherapy plans. A quantitative analysis of the dose distributions and dose-volume histograms shows that both Co-60 and 6 MV plans achieve the plan objectives for the targets (CTV and nodes and OARs (spinal cord in HandN case, and rectum in prostate case.

Neutron data compilation. Report of a Panel sponsored by the International Atomic Energy Agency and held in Brookhaven, 10-14 February 1969

Energy Technology Data Exchange (ETDEWEB)

NONE

1969-02-15

The IAEA organized and convened a Panel on Neutron Data Compilation. This Panel was organized by the Agency following the recommendations made by the International Nuclear Data Committee (INDC) which agreed that a general review of world neutron data compilation activities was desirable. In this context neutron data compilation encompasses the collection, storage and dissemination of bibliographic information and of qualitative and numerical data on the interaction of neutrons with nuclei and atoms for all incident energies. Such information and data have important applications in low energy neutron physics and many important. areas of nuclear technology. The principal objective of the Panel on Neutron Data Compilation, Which was held at Brookhaven National Laboratory during 10-14 February 1969, was to review how the world's principal data centers located at Brookhaven, Saclay, Obninsk and Vienna could ideally meet the demands and needs of experimental and theoretical neutron physicists, evaluators, reactor physicists as well as other existing and potential users. Fourteen papers were considered during formal sessions of the Panel and are reported on the following pages. The members of the Panel separated into five working groups to consider specific terms of references and make recommendations. Their reports were discussed.

Best research practices in psychology: Illustrating epistemological and pragmatic considerations with the case of relationship science.

Science.gov (United States)

Finkel, Eli J; Eastwick, Paul W; Reis, Harry T

2015-02-01

In recent years, a robust movement has emerged within psychology to increase the evidentiary value of our science. This movement, which has analogs throughout the empirical sciences, is broad and diverse, but its primary emphasis has been on the reduction of statistical false positives. The present article addresses epistemological and pragmatic issues that we, as a field, must consider as we seek to maximize the scientific value of this movement. Regarding epistemology, this article contrasts the false-positives-reduction (FPR) approach with an alternative, the error balance (EB) approach, which argues that any serious consideration of optimal scientific practice must contend simultaneously with both false-positive and false-negative errors. Regarding pragmatics, the movement has devoted a great deal of attention to issues that frequently arise in laboratory experiments and one-shot survey studies, but it has devoted less attention to issues that frequently arise in intensive and/or longitudinal studies. We illustrate these epistemological and pragmatic considerations with the case of relationship science, one of the many research domains that frequently employ intensive and/or longitudinal methods. Specifically, we examine 6 research prescriptions that can help to reduce false-positive rates: preregistration, prepublication sharing of materials, postpublication sharing of data, close replication, avoiding piecemeal publication, and increasing sample size. For each, we offer concrete guidance not only regarding how researchers can improve their research practices and balance the risk of false-positive and false-negative errors, but also how the movement can capitalize upon insights from research practices within relationship science to make the movement stronger and more inclusive. PsycINFO Database Record (c) 2015 APA, all rights reserved.

Viscous liquid barrier demonstration at the Brookhaven National Laboratory Linac Isotope Producer

International Nuclear Information System (INIS)

Heiser, J.H.; Sullivan, T.; Ludewig, H.; Brower, J.; North-Abbott, M.; Manchester, K.; Zaluski, M.; Penny, G.

2000-01-01

Groundwater monitoring has detected tritium ( 3 H) and 22 Na contamination down gradient from the Brookhaven LINAC Isotope Producer (BLIP), located at Brookhaven National Laboratory (BNL). Site characterization studies indicate that the BLIP is the source of contamination. The highest measured values for 3 H were 52,400 pCi/L recorded less than 100 feet south (down gradient) of the BLIP facility. The BLIP produces radioisotopes that are crucial in nuclear medicine for both research and clinical use. The BLIP also supports research on diagnostic and therapeutic radiopharmaceuticals. During operation a proton beam impinges a target (typically salts encapsulated in stainless steel) to produce the required radioisotopes. The proton beam is completely absorbed prior to reaching the soils surrounding the target shaft. However, secondary neutrons are produced that reach the soil causing activation products to form. Among the longer-lived isotopes of concern are tritium and 22 Na. Both of these isotopes have the potential to negatively impact the groundwater below the BLIP. Several corrective actions have been implemented at the BLIP facility in response to tritium detection in the groundwater. The first actions were to improve surface water management (e.g. storm water down spouts) and the installation of a gunite cap around the BLIP facility. These measures are designed to minimize water flow through the activated soils in the vicinity of BLIP. In conjunction with these improvements, BNL is installing a close-proximity subsurface barrier in the activated soils beneath the BLIP facility. The barrier will prevent water migration through the activated soil zone as well as prevent activation product migration out of the zone. To minimize impacts on the operation of the BLIP requires in-situ barrier installation using low energy techniques that will not disturb the alignment of the BLIP or nearby accelerator beams. BNL chose an innovative barrier technology termed Viscous

Construction and operation of a 10 MeV electron accelerator and associated experimental facilities at Brookhaven National Laboratory, Upton, New York. Environmental assessment

International Nuclear Information System (INIS)

1994-02-01

The purpose of this environmental impact statement is to determine whether there would be significant environmental impacts associated with the construction of an experimental facility at Brookhaven National Laboratory for radiation chemistry research and operation of the 10-MeV electron accelerator proposed for it. The document describes the need for action, alternative actions, the affected environment, and potential environmental impacts

Decommissioning of the High Flux Beam Reactor at Brookhaven Lab

Energy Technology Data Exchange (ETDEWEB)

Hu, J. P. [Brookhaven National Lab. (BNL), Upton, NY (United States); Reciniello, R. N. [Brookhaven National Lab. (BNL), Upton, NY (United States); Holden, N. E. [Brookhaven National Lab. (BNL), Upton, NY (United States)

2011-05-27

The High Flux Beam Reactor at the Brookhaven National Laboratory was a heavy water cooled and moderated reactor that achieved criticality on October 31, 1965. It operated at a power level of 40 mega-watts. An equipment upgrade in 1982 allowed operations at 60 mega-watts. After a 1989 reactor shutdown to reanalyze safety impact of a hypothetical loss of coolant accident, the reactor was restarted in 1991 at 30 mega-watts. The HFBR was shutdown in December 1996 for routine maintenance and refueling. At that time, a leak of tritiated water was identified by routine sampling of ground water from wells located adjacent to the reactor’s spent fuel pool. The reactor remained shutdown for almost three years for safety and environmental reviews. In November 1999 the United States Department of Energy decided to permanently shutdown the HFBR. The decontamination and decommissioning of the HFBR complex, consisting of multiple structures and systems to operate and maintain the reactor, were complete in 2009 after removing and shipping off all the control rod blades. The emptied and cleaned HFBR dome which still contains the irradiated reactor vessel is presently under 24/7 surveillance for safety. Details of the HFBR cleanup conducted during 1999-2009 will be described in the paper.

Environmental Survey preliminary report, Brookhaven National Laboratory, Upton, New York

Energy Technology Data Exchange (ETDEWEB)

1988-06-01

This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Brookhaven National Laboratory (BNL) conducted April 6 through 17, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team components are being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with BNL. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at BNL, and interviews with site personnel. The Survey team developed a Sampling and Analysis Plan to assist in further assessing specific environmental problems identified during its on-site activities. The Sampling and Analysis Plan will be executed by Oak Ridge National Laboratory. When completed, the results will be incorporated into the BNL Environmental Survey Interim Report. The Interim Report will reflect the final determinations of the BNL Survey. 80 refs., 24 figs., 48 tabs.

Environmental Survey preliminary report, Brookhaven National Laboratory, Upton, New York

International Nuclear Information System (INIS)

1988-06-01

This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Brookhaven National Laboratory (BNL) conducted April 6 through 17, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team components are being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with BNL. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at BNL, and interviews with site personnel. The Survey team developed a Sampling and Analysis Plan to assist in further assessing specific environmental problems identified during its on-site activities. The Sampling and Analysis Plan will be executed by Oak Ridge National Laboratory. When completed, the results will be incorporated into the BNL Environmental Survey Interim Report. The Interim Report will reflect the final determinations of the BNL Survey. 80 refs., 24 figs., 48 tabs

Game theoretic considerations for Kenyan health governance ...

African Journals Online (AJOL)

Game theoretic considerations for Kenyan health governance. ... theoretic considerations in their practice in order to achieve market-driven competition ... Key words: Game theory, social capital, good governance, health policy, health systems.

Recombinant Science: The Birth of the Relativistic Heavy Ion Collider (431st Brookhaven Lecture)

International Nuclear Information System (INIS)

Crease, Robert P.

2007-01-01

As part of the celebration of Brookhaven Lab's 60th anniversary, Robert P. Crease, the Chair of the Philosophy Department at Stony Brook University and BNL's historian, will present the second of two talks on the Lab's history. In 'Recombinant Science: The Birth of the Relativistic Heavy Ion Collider,' Dr. Crease will focus on the creation of the world's most powerful colliding accelerator for nuclear physics. Known as RHIC, the collider, as Dr. Crease will recount, was formally proposed in 1984, received initial construction funding from the U.S. Department of Energy in 1991, and started operating in 2000. In 2005, the discovery at RHIC of the world's most perfect liquid, a state of matter that last existed just moments after the Big Bang, was announced, and, since then, this perfect liquid of quarks and gluons has been the subject of intense study.

Measurement of ac electrical characteristics of SSC dipole magnets at Brookhaven

International Nuclear Information System (INIS)

Smedley, K.

1992-04-01

The SSC collider is designed to have circumference of 87 km. The superconducting magnets along the collider ring are grouped into ten sectors. Each sector, a string of average length of 8.7 km,m is powered by one power source located near the center of the sector. Because of the alternating-current (ac) electrical characteristics of the magnets, the power supply ripple currents and transients form a time and space distribution in the magnet string which affects particle motions. Additionally, since the power supply load is a magnet string, the current regulation loop design is highly dependent upon the ac electrical characteristics of the magnets. A means is needed to accurately determine the ac electrical characteristics of the superconducting magnets. The ac characteristics of magnets will be used to predict the ripple distribution of the long string of superconducting magnets. Magnet ac characteristics can also provide necessary information for the regulation loop design. This paper presents a method for measuring the ac characteristics of superconducting magnets. Two collider dipole magnets, one superconducting and one at room temperature, were tested at Brookhaven National Lab

Retrospective review of the clinical BNCT trial at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Diaz, A.Z.; Chanana, A.D.; Coderre, J.A.; Ma, R.

2000-01-01

The primary objective of the phase I/II dose escalation studies was to evaluate the safety of the boronophenylalanine-fructose (BPA-F) mediated boron neutron capture therapy (BNCT) in subjects with glioblastoma multiforme (GBM). A secondary objective was to retrospectively assess the palliation of GBM by BNCT. Fifty-three subjects with GBM were treated under multiple dose escalation protocols at the Brookhaven Medical Research Reactor (BMRR). Twenty-six subjects were treated using one field, 17 subjects were treated using 2 fields and 10 subjects were treated using 3 fields. BPA-F related toxicity was not observed. The maximum radiation dose to a volume of approximately 1 cc of the normal brain varied from 8.9 to 15.9 gray-equivalent (Gy-Eq). The volume-weighted average radiation dose to normal brain varied from 1.9 to 9.5 Gy-Eq. Six RTOG (Radiation Therapy Oncology Group) grade 3 or 4 toxicities were attributed to BNCT. Four of the 53 subjects are still alive with 3 of them free of recurrent disease with over two years follow-up. The median times to progression and median survival time from diagnosis were 28.4 weeks and 12.8 months respectively. (author)

The Shape and Flow of Heavy Ion Collisions (490th Brookhaven Lecture)

Energy Technology Data Exchange (ETDEWEB)

Schenke, Bjoern [BNL Physics Department

2014-12-18

The sun can’t do it, but colossal machines like the Relativistic Heavy Ion Collider (RHIC) at Brookhaven Lab and Large Hadron Collider (LHC) in Europe sure can. Quarks and gluons make up protons and neutrons found in the nucleus of every atom in the universe. At heavy ion colliders like RHIC and the LHC, scientists can create matter more than 100,000 times hotter than the center of the sun—so hot that protons and neutrons melt into a plasma of quarks and gluons. The particle collisions and emerging quark-gluon plasma hold keys to understanding how these fundamental particles interact with each other, which helps explain how everything is held together—from atomic nuclei to human beings to the biggest stars—how all matter has mass, and what the universe looked like microseconds after the Big Bang. Dr. Schenke discusses theory that details the shape and structure of heavy ion collisions. He will also explain how this theory and data from experiments at RHIC and the LHC are being used to determine properties of the quark-gluon plasma.

Direct-Acting Oral Anticoagulants: Practical Considerations for Emergency Medicine Physicians

Directory of Open Access Journals (Sweden)

W. Frank Peacock

2016-01-01

Full Text Available Nonvalvular atrial fibrillation- (NVAF- related stroke and venous thromboembolism (VTE are cardiovascular diseases associated with significant morbidity and economic burden. The historical standard treatment of VTE has been the administration of parenteral heparinoid until oral warfarin therapy attains a therapeutic international normalized ratio. Warfarin has been the most common medication for stroke prevention in NVAF. Warfarin use is complicated by a narrow therapeutic window, unpredictable dose response, numerous food and drug interactions, and requirements for frequent monitoring. To overcome these disadvantages, direct-acting oral anticoagulants (DOACs—dabigatran, rivaroxaban, apixaban, and edoxaban—have been developed for the prevention of stroke or systemic embolic events (SEE in patients with NVAF and for the treatment of VTE. Advantages of DOACs include predictable pharmacokinetics, few drug-drug interactions, and low monitoring requirements. In clinical studies, DOACs are noninferior to warfarin for the prevention of NVAF-related stroke and the treatment and prevention of VTE as well as postoperative knee and hip surgery VTE prophylaxis, with decreased bleeding risks. This review addresses the practical considerations for the emergency physician in DOAC use, including dosing recommendations, laboratory monitoring, anticoagulation reversal, and cost-effectiveness. The challenges of DOACs, such as the lack of specific laboratory measurements and antidotes, are also discussed.

NATURAL RESOURCE MANAGEMENT PLAN FOR BROOKHAVEN NATIONAL LABORATORY.

Energy Technology Data Exchange (ETDEWEB)

GREEN,T.ET AL.

2003-12-31

Brookhaven National Laboratory (BNL) is located near the geographic center of Long Island, New York. The Laboratory is situated on 5,265 acres of land composed of Pine Barrens habitat with a central area developed for Laboratory work. In the mid-1990s BNL began developing a wildlife management program. This program was guided by the Wildlife Management Plan (WMP), which was reviewed and approved by various state and federal agencies in September 1999. The WMP primarily addressed concerns with the protection of New York State threatened, endangered, or species of concern, as well as deer populations, invasive species management, and the revegetation of the area surrounding the Relativistic Heavy Ion Collider (RHIC). The WMP provided a strong and sound basis for wildlife management and established a basis for forward motion and the development of this document, the Natural Resource Management Plan (NRMP), which will guide the natural resource management program for BNL. The body of this plan establishes the management goals and actions necessary for managing the natural resources at BNL. The appendices provide specific management requirements for threatened and endangered amphibians and fish (Appendices A and B respectively), lists of actions in tabular format (Appendix C), and regulatory drivers for the Natural Resource Program (Appendix D). The purpose of the Natural Resource Management Plan is to provide management guidance, promote stewardship of the natural resources found at BNL, and to integrate their protection with pursuit of the Laboratory's mission. The philosophy or guiding principles of the NRMP are stewardship, adaptive ecosystem management, compliance, integration with other plans and requirements, and incorporation of community involvement, where applicable.

The first terawatt picosecond CO2 laser for advanced accelerator studies at the Brookhaven ATF

International Nuclear Information System (INIS)

Pogorelsky, I.V.; Ben-Zvi, I.; Skaritka, J.

1996-10-01

The first terawatt picosecond C0 2 laser system is under development at the Brookhaven Accelerator Test Facility. Presently operational 1 Joule 100-ps ATF laser will be upgraded with a 10 atm amplifier capable of delivery ∼ 15 Joules of laser energy in a 3 ps pulse. We describe the design of the x-ray preionized 10 atm amplifier of a 10 liter active volume energized by a 1 MV, 200 kA transverse electric discharge. The amplifier, equipped with internal optics, permits the accommodation of a regenerative stage and a multi-pass booster in a relatively compact single discharge volume. The ATF terawatt C0 2 laser shall become operational in 1997 to serve for laser acceleration, x-ray generation and other strong-field physics experiments

Production of platinum radioisotopes at Brookhaven Linac Isotope Producer (BLIP

Directory of Open Access Journals (Sweden)

Smith Suzanne V.

2017-01-01

Full Text Available The accelerator production of platinum isotopes was investigated at the Brookhaven Linac Isotope Producer (BLIP. In this study high purity natural platinum foils were irradiated at 53.2, 65.7, 105.2, 151.9, 162.9 and 173.3.MeV. The irradiated foils were digested in aqua regia and then converted to their hydrochloride salt with concentrated hydrochloric acid before analyzing by gamma spectrometry periodically for at least 10 days post end of bombardment. A wide range of platinum (Pt, gold (Au and iridium (Ir isotopes were identified. Effective cross sections at BLIP for Pt-188, Pt-189, Pt-191 and Pt-195m were compared to literature and theoretical cross sections determined using Empire-3.2. The majority of the effective cross sections (<70 MeV confirm those reported in the literature. While the absolute values of the theoretical cross sections were up to a factor of 3 lower, Empire 3.2 modeled thresholds and maxima correlated well with experimental values. Preliminary evaluation into a rapid separation of Pt isotopes from high levels of Ir and Au isotopes proved to be a promising approach for large scale production. In conclusion, this study demonstrated that with the use of isotopically enriched target material accelerator production of selected platinum isotopes is feasible over a wide proton energy range.

Risk assessment and optimization (ALARA) analysis for the environmental remediation of Brookhaven National Laboratory's hazardous waste management facility

International Nuclear Information System (INIS)

Dionne, B.J.; Morris, S. III; Baum, J.W.

1998-03-01

The Department of Energy's (DOE) Office of Environment, Safety, and Health (EH) sought examples of risk-based approaches to environmental restoration to include in their guidance for DOE nuclear facilities. Extensive measurements of radiological contamination in soil and ground water have been made at Brookhaven National Laboratory's Hazardous Waste Management Facility (HWMF) as part of a Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) remediation process. This provided an ideal opportunity for a case study. This report provides a risk assessment and an open-quotes As Low as Reasonably Achievableclose quotes (ALARA) analysis for use at other DOE nuclear facilities as an example of a risk-based decision technique

Telerehabilitation store and forward applications: a review of applications and privacy considerations in physical and occupational therapy practice.

Science.gov (United States)

Peterson, Christopher; Watzlaf, Valerie

2014-01-01

An overview of store and forward applications commonly used in physical and occupational therapy practice is reviewed with respect to regulation, privacy, security, and clinical applications. A privacy and security checklist provides a clear reference of pertinent regulatory issues regarding these software applications. A case study format is used to highlight clinical applications of store and forward software features. Important considerations of successful implementation of store and forward applications are also identified and discussed.

Neutrino oscillation study in the muon neutrino → electron neutrino channel at the Brookhaven accelerator

International Nuclear Information System (INIS)

Astier, P.

1987-09-01

The E816 experiment described in this thesis is devoted to a neutrino oscillation search at the Brookhaven AGS. The method used here is to look with a fine grained calorimeter for the appearence of electron neutrino in a muon neutrino beam. After recalling the theoretical treatment of the neutrino mass problem, the experimental phenomenology of massive neutrinos and more specifically neutrino oscillations is reviewed. The experiment itself is then extensively described, both on the technical side (detector, beam, simulation) and on the analysis side. In particular the statistical separation of the electromagnetic showers from electrons - our signal - and from photons - our background - treated in detail. The present analysis is based on 2/3 of the final statistics and it leads to the - preliminary - observation of an electron excess in the neutrino interactions yielding 19 ± 15.6 (stat) ± 7 (syst) [fr

Brookhaven National Laboratory 2008 Site Environment Report Volume 1

Energy Technology Data Exchange (ETDEWEB)

Brookhaven National Laboratory

2009-10-01

Brookhaven National Laboratory (BNL) prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1A, Environment, Safety and Health Reporting of the U.S. Department of Energy. The report is written to inform the public, regulators, employees, and other stakeholders of the Laboratory's environmental performance during the calendar year in review. Volume I of the SER summarizes environmental data; environmental management performance; compliance with applicable DOE, federal, state, and local regulations; and performance in restoration and surveillance monitoring programs. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inception in 1947. Volume II of the SER, the Groundwater Status Report, also is prepared annually to report on the status of and evaluate the performance of groundwater treatment systems at the Laboratory. Volume II includes detailed technical summaries of groundwater data and its interpretation, and is intended for internal BNL users, regulators, and other technically oriented stakeholders. A brief summary of the information contained in Volume II is included in this volume in Chapter 7, Groundwater Protection. Both reports are available in print and as downloadable files on the BNL web page at http://www.bnl.gov/ewms/ser/. An electronic version on compact disc is distributed with each printed report. In addition, a summary of Volume I is prepared each year to provide a general overview of the report, and is distributed with a compact disc containing the full report.

IEEE 1394 CAMERA IMAGING SYSTEM FOR BROOKHAVENS BOOSTER APPLICATION FACILITY BEAM DIAGNOSTICS

International Nuclear Information System (INIS)

BROWN, K.A.; FRAK, B.; GASSNER, D.; HOFF, L.; OLSEN, R.H.; SATOGATA, T.; TEPIKIAN, S.

2002-01-01

Brookhaven's Booster Applications Facility (BAF) will deliver resonant extracted heavy ion beams from the AGS Booster to short-exposure fixed-target experiments located at the end of the BAF beam line. The facility is designed to deliver a wide range of heavy ion species over a range of intensities from 10 3 to over 10 8 ions/pulse, and over a range of energies from 0.1 to 3.0 GeV/nucleon. With these constraints we have designed instrumentation packages which can deliver the maximum amount of dynamic range at a reasonable cost. Through the use of high quality optics systems and neutral density light filters we will achieve 4 to 5 orders of magnitude in light collection. By using digital IEEE1394 camera systems we are able to eliminate the frame-grabber stage in processing and directly transfer data at maximum rates of 400 Mb/set. In this note we give a detailed description of the system design and discuss the parameters used to develop the system specifications. We will also discuss the IEEE1394 camera software interface and the high-level user interface

Review of the {sup 60}Co Source. Development Program at Brookhaven National Laboratory; Le Programme de Mise au Point des Sources au {sup 60}Co au Laboratoire National de Brookhaven; Obzor programmy po razrabotke istochnikov {sup 60}Co v brukkhejvenskoj natsional'noj laboratorii; El Programa de Preparacion de Fuentes de {sup 60}Co del Laboratorio Nacional de Brookhaven

Energy Technology Data Exchange (ETDEWEB)

Kuhl, O. A. [Brookhaven National Laboratory, Upton, NY (United States)

1966-11-15

Early in the 1950's, at the request of the United States Atomic Energy Commission, Brookhaven National Laboratory (BNL) undertook the development of radiation sources. These sources were mainly of two types: large tubes, and flat strips. Initially these were used for research at BNL. Later, other institutions were permitted to use the irradiation facilities designed for these sources. As interest grew, source-irradiator combinations were made available to other researchers. Shipping containers for sources were developed. Small hot cells and water-filled pools were constructed to utilize the sources. Methods of dosimetry, curie evaluation, and irradiator design for these sources are discussed in this paper. During the research stages, economics were not usually important; however, the trend toward large- scale radiation processing in the field of food, chemicals and medical supplies will require careful consideration of the technical and economic aspects of source design. The development of the BNL Standard Mark I and Mark II Sources, already in use in a number of' facilities, is to satisfy these important requirements. The Mark I and Mark II sources are interchangeable. An improvement in the Mark II element design is that the inner cladding is metallurgically bonded to the cobalt core. It is now possible, for the first time, to reactivate these source elements after a period of use. Individual strips are sized for easy arrangement in plaques of various dimensions and shapes. The design philosophy, fabrication techniques, and test procedures, together with source analysis and curie evaluation, are described. Comparisons are made with other source types currently in use and economical and technical advantages are discussed. (author) [French] A la demande de la Commission de l'energie atomique des Etats-Unis, le Laboratoire national de Brookhaven a entrepris des les annees 50 la mise au point de sources de rayonnement. Ces sources etaient principalement de deux types

Telerehabilitation Store and Forward Applications: A Review of Applications and Privacy Considerations in Physical and Occupational Therapy Practice

Directory of Open Access Journals (Sweden)

Christopher Peterson

2015-01-01

Full Text Available An overview of store and forward applications commonly used in physical and occupational therapy practice is reviewed with respect to regulation, privacy, security, and clinical applications. A privacy and security checklist provides a clear reference of pertinent regulatory issues regarding these software applications. A case study format is used to highlight clinical applications of store and forward software features. Important considerations of successful implementation of store and forward applications are also identified and discussed.

Higher-order-mode absorbers for energy recovery linac cryomodules at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Hahn, H.; Ben-Zvi, I.; Calaga, R.; Hammons, L.; Johnson, E.C.; Kewisch, J.; Litvinenko, V.N.; Xu, W.

2010-01-01

Several future accelerator projects at Brookhaven for the Relativistic Heavy Ion Collider (RHIC) are based on energy recovery linacs (ERLs) with high-charge high-current electron beams. Their stable operation mandates effective higher-order-mode (HOM) damping. The development of HOM dampers for these projects is pursued actively at this laboratory. Strong HOM damping was experimentally demonstrated both at room and at superconducting (SC) temperatures in a prototype research and development (R and D) five-cell niobium superconducting rf (SRF) cavity with ferrite dampers. Two room-temperature mock-up five-cell copper cavities were used to study various damper configurations with emphasis on capacitive antenna dampers. An innovative type of ferrite damper over a ceramic break for an R and D SRF electron gun also was developed. For future SRF linacs longer cryomodules comprised of multiple superconducting cavities with reasonably short intercavity transitions are planned. In such a configuration, the dampers, located closer to the cavities, will be at cryogenic temperatures; this will impose additional constraints and complications. This paper presents the results of simulations and measurements of several damper configurations.

Higher-order-mode absorbers for energy recovery linac cryomodules at Brookhaven National Laboratory

Science.gov (United States)

Hahn, H.; Ben-Zvi, I.; Calaga, R.; Hammons, L.; Johnson, E. C.; Kewisch, J.; Litvinenko, V. N.; Xu, Wencan

2010-12-01

Several future accelerator projects at Brookhaven for the Relativistic Heavy Ion Collider (RHIC) are based on energy recovery linacs (ERLs) with high-charge high-current electron beams. Their stable operation mandates effective higher-order-mode (HOM) damping. The development of HOM dampers for these projects is pursued actively at this laboratory. Strong HOM damping was experimentally demonstrated both at room and at superconducting (SC) temperatures in a prototype research and development (R&D) five-cell niobium superconducting rf (SRF) cavity with ferrite dampers. Two room-temperature mock-up five-cell copper cavities were used to study various damper configurations with emphasis on capacitive antenna dampers. An innovative type of ferrite damper over a ceramic break for an R&D SRF electron gun also was developed. For future SRF linacs longer cryomodules comprised of multiple superconducting cavities with reasonably short intercavity transitions are planned. In such a configuration, the dampers, located closer to the cavities, will be at cryogenic temperatures; this will impose additional constraints and complications. This paper presents the results of simulations and measurements of several damper configurations.

Higher-order-mode absorbers for energy recovery linac cryomodules at Brookhaven National Laboratory

Directory of Open Access Journals (Sweden)

H. Hahn

2010-12-01

Full Text Available Several future accelerator projects at Brookhaven for the Relativistic Heavy Ion Collider (RHIC are based on energy recovery linacs (ERLs with high-charge high-current electron beams. Their stable operation mandates effective higher-order-mode (HOM damping. The development of HOM dampers for these projects is pursued actively at this laboratory. Strong HOM damping was experimentally demonstrated both at room and at superconducting (SC temperatures in a prototype research and development (R&D five-cell niobium superconducting rf (SRF cavity with ferrite dampers. Two room-temperature mock-up five-cell copper cavities were used to study various damper configurations with emphasis on capacitive antenna dampers. An innovative type of ferrite damper over a ceramic break for an R&D SRF electron gun also was developed. For future SRF linacs longer cryomodules comprised of multiple superconducting cavities with reasonably short intercavity transitions are planned. In such a configuration, the dampers, located closer to the cavities, will be at cryogenic temperatures; this will impose additional constraints and complications. This paper presents the results of simulations and measurements of several damper configurations.

Massachusetts Institute of Technology School of Chemical Engineering Practice, Brookhaven station: Summary of projects, 1983-1986

International Nuclear Information System (INIS)

1987-11-01

The MIT Graduate School of Chemical Engineering Practice stresses engineering problem solving. The Practice School program, as it is commonly called, develops in a unique and particularly effective way the student's ability to apply fundamentals to problems in the chemical industry and thus accelerates one's professional development. The themes of atomization, emthanol production and utilization, hydrogen production and compression, localized electrochemical corrosion and biochemical engineering reflect some of the major programs at the Laboratory. The titles of all the projects are listed in chronological order in the index at the end of this document. Brief summaries are presented for each project with related projects grouped together

DECOMMISSIONING THE BROOKHAVEN NATIONAL LABORATORY BUILDING 830 GAMMA IRRADIATION FACILITY.

Energy Technology Data Exchange (ETDEWEB)

BOWERMAN, B.S.; SULLIVAN, P.T.

2001-08-13

The Building 830 Gamma Irradiation Facility (GIF) at Brookhaven National Laboratory (BNL) was decommissioned because its design was not in compliance with current hazardous tank standards and its cobalt-60 sources were approaching the end of their useful life. The facility contained 354 stainless steel encapsulated cobalt-60 sources in a pool, which provided shielding. Total cobalt-60 inventory amounted to 24,000 Curies when the sources were shipped for disposal. The decommissioning project included packaging, transport, and disposal of the sources and dismantling and disposing of all other equipment associated with the facility. Worker exposure was a major concern in planning for the packaging and disposal of the sources. These activities were planned carefully according to ALARA (As Low As Reasonably Achievable) principles. As a result, the actual occupational exposures experienced during the work were within the planned levels. Disposal of the pool water required addressing environmental concerns, since the planned method was to discharge the slightly contaminated water to the BNL sewage treatment plant. After the BNL evaluation procedure for discharge to the sewage treatment plant was revised and reviewed by regulators and BNL's Community Advisory Council, the pool water was discharged to the Building 830 sanitary system. Because the sources were sealed and the pool water contamination levels were low, most of the remaining equipment was not contaminated; therefore disposal was straightforward, as scrap metal and construction debris.

Risk assessment and optimization (ALARA) analysis for the environmental remediation of Brookhaven National Laboratory's hazardous waste management facility

International Nuclear Information System (INIS)

Dionne, B.J.; Morris, S.C. III; Baum, J.W.

1998-01-01

The Department of Energy's (DOE) Office of Environment, Safety, and Health (EH) sought examples of risk-based approaches to environmental restoration to include in their guidance for DOE nuclear facilities. Extensive measurements of radiological contamination in soil and ground water have been made at Brookhaven National Laboratory's Hazardous Waste Management Facility (HWMF) as part of a Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) remediation process. This provided an ideal opportunity for a case study. This report provides a risk assessment and an open-quotes As Low as Reasonably Achievableclose quotes (ALARA) analysis for use at other DOE nuclear facilities as an example of a risk-based decision technique. This document contains the Appendices for the report

32 CFR 643.83 - Consideration.

Science.gov (United States)

2010-07-01

... consideration in an amount equal to the fair market value as established by recognized appraisal practices. As... thereof, will not require fair market value when the purpose of the easement is to serve the public...

Landscape analysis: Theoretical considerations and practical needs

Science.gov (United States)

Godfrey, A.E.; Cleaves, E.T.

1991-01-01

Numerous systems of land classification have been proposed. Most have led directly to or have been driven by an author's philosophy of earth-forming processes. However, the practical need of classifying land for planning and management purposes requires that a system lead to predictions of the results of management activities. We propose a landscape classification system composed of 11 units, from realm (a continental mass) to feature (a splash impression). The classification concerns physical aspects rather than economic or social factors; and aims to merge land inventory with dynamic processes. Landscape units are organized using a hierarchical system so that information may be assembled and communicated at different levels of scale and abstraction. Our classification uses a geomorphic systems approach that emphasizes the geologic-geomorphic attributes of the units. Realm, major division, province, and section are formulated by subdividing large units into smaller ones. For the larger units we have followed Fenneman's delineations, which are well established in the North American literature. Areas and districts are aggregated into regions and regions into sections. Units smaller than areas have, in practice, been subdivided into zones and smaller units if required. We developed the theoretical framework embodied in this classification from practical applications aimed at land use planning and land management in Maryland (eastern Piedmont Province near Baltimore) and Utah (eastern Uinta Mountains). ?? 1991 Springer-Verlag New York Inc.

Considerations for use of dental photography and electronic media in dental education and clinical practice.

Science.gov (United States)

Stieber, Jane C; Nelson, Travis; Huebner, Colleen E

2015-04-01

Photography and electronic media are indispensable tools for dental education and clinical practice. Although previous research has focused on privacy issues and general strategies to protect patient privacy when sharing clinical photographs for educational purposes, there are no published recommendations for developing a functional, privacy-compliant institutional framework for the capture, storage, transfer, and use of clinical photographs and other electronic media. The aims of this study were to research patient rights relating to electronic media and propose a framework for the use of patient media in education and clinical care. After a review of the relevant literature and consultation with the University of Washington's director of privacy and compliance and assistant attorney general, the researchers developed a privacy-compliant framework to ensure appropriate capture, storage, transfer, and use of clinical photography and electronic media. A four-part framework was created to guide the use of patient media that reflects considerations of patient autonomy and privacy, informed consent, capture and storage of media, and its transfer, use, and display. The best practices proposed for capture, storage, transfer, and use of clinical photographs and electronic media adhere to the health care code of ethics (based on patient autonomy, nonmaleficence, beneficence, justice, and veracity), which is most effectively upheld by a practical framework designed to protect patients and limit institutional liability. Educators have the opportunity and duty to convey these principles to students who will become the next generation of dentists, researchers, and educators.

Identification of important ''PIUS'' design considerations and accident sequences using qualitative plant assessment techniques

International Nuclear Information System (INIS)

Higgins, J.; Fullwood, R.; Kroeger, P.; Youngblood, R.

1992-01-01

The PIUS (Process Inherent Ultimate Safety) reactor is an advanced design nuclear power plant that uses passive safety features and basic physical processes to address safety concerns. Brookhaven National Laboratory (BNL) performed a detailed study of the PIUS design for the NRC using primarily qualitative engineering analysis techniques. Some quantitative methods were also employed. There are three key initial areas of analysis: FMECA, HAZOP, and deterministic analyses, which are described herein. Once these three analysis methods were completed, the important findings from each of the methods were assembled into thePIUS Interim Table (PIT). This table thus contains a first cut sort of the important design considerations and features of the PIUS reactor. The table also identifies some potential initiating events and systems used for mitigating these initiators. The next stage of the analysis was the construction of event trees for each of the identified initiators. The most significant sequences were then determined qualitatively, using, some quantitative input. Finally, overall insights on the PIUS design developed from the PIT and from the event tree analysis were developed and presented

Decommissioning of the High Flux Beam Reactor at Brookhaven National Laboratory.

Science.gov (United States)

Hu, Jih-Perng; Reciniello, Richard N; Holden, Norman E

2012-08-01

The High Flux Beam Reactor (HFBR) at the Brookhaven National Laboratory was a heavy-water cooled and moderated reactor that achieved criticality on 31 October 1965. It operated at a power level of 40 mega-watts. An equipment upgrade in 1982 allowed operations at 60 mega-watts. After a 1989 reactor shutdown to reanalyze safety impact of a hypothetical loss of coolant accident, the reactor was restarted in 1991 at 30 mega-watts. The HFBR was shut down in December 1996 for routine maintenance and refueling. At that time, a leak of tritiated water was identified by routine sampling of ground water from wells located adjacent to the reactor's spent fuel pool. The reactor remained shut down for almost 3 y for safety and environmental reviews. In November 1999, the United States Department of Energy decided to permanently shut down the HFBR. The decontamination and decommissioning of the HFBR complex, consisting of multiple structures and systems to operate and maintain the reactor, were complete in 2009 after removing and shipping off all the control rod blades. The emptied and cleaned HFBR dome, which still contains the irradiated reactor vessel is presently under 24/7 surveillance for safety. Details of the HFBR's cleanup performed during 1999-2009, to allow the BNL facilities to be re-accessed by the public, will be described in the paper.

Dental considerations in cardiovascular patients: A practical perspective

OpenAIRE

Chaudhry, Swantika; Jaiswal, Ritika; Sachdeva, Surender

2016-01-01

Cardiovascular disease trends, complications, and associated therapeutics impact the dental health and treatment. Such patients require special consideration with regard to when and which dental treatment is appropriate and what precautions are required. Alertness to potential oral adverse drug reactions enables referral of patient's to his physician or cardiologist. Cardiovascular drugs are also known to have mild to potentially fatal drug interactions. Dental professionals may be the first ...

OPTIMIZATION OF THE EPITHERMAL NEUTRON BEAM FOR BORON NEUTRON CAPTURE THERAPY AT THE BROOKHAVEN MEDICAL RESEARCH REACTOR.

Energy Technology Data Exchange (ETDEWEB)

HU,J.P.; RORER,D.C.; RECINIELLO,R.N.; HOLDEN,N.E.

2002-08-18

Clinical trials of Boron Neutron Capture Therapy for patients with malignant brain tumor had been carried out for half a decade, using an epithermal neutron beam at the Brookhaven's Medical Reactor. The decision to permanently close this reactor in 2000 cut short the efforts to implement a new conceptual design to optimize this beam in preparation for use with possible new protocols. Details of the conceptual design to produce a higher intensity, more forward-directed neutron beam with less contamination from gamma rays, fast and thermal neutrons are presented here for their potential applicability to other reactor facilities. Monte Carlo calculations were used to predict the flux and absorbed dose produced by the proposed design. The results were benchmarked by the dose rate and flux measurements taken at the facility then in use.

A survey of the high energy physics program at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Hahn, H.; Rau, R.R.; Wanderer, P.

1977-01-01

About fifteen years ago the Alternating Gradient Synchrotron (AGS) at Brookhaven National Laboratory began operating for high energy particle physics experiments. A wealth of important results has been published, capped by four discoveries which have changed the field dramatically. These discoveries are: the muon neutrino, γsub(μ); the strangeness minus three Ω - baryon; CP violation in K 0 decay; and recently the totally unpredicted J/psi particle. The experimental program has broadened, matured and increased in scope following a large improvement program at the AGS. Major developments included: replacement of the original 50 MeV linear accelerator injector by a modern 200 MeV linac; construction of two new experimental areas, one for neutrino experiments and the other for counter-spark chamber electronics experiments, with the philosophy that nearly all circulating protons would be extracted from the machine and directed onto targets external to the machine; raising the circulating proton intensity to a maximum of 10 13 protons, and installation of a new magnet supply allowing a cycle of 2.4 seconds with a 1 second flat-top, or a 40% duty cycle. The paper also describes a crucial function of any particle physics laboratory, the plans and research directed toward new facilities to make available new regions for particle physics research. (Auth.)

A new high resolution neutron powder diffractometer at the Brookhaven high flux beam reactor

International Nuclear Information System (INIS)

Passell, L.; Bar-Ziv, S.; Gardner, D.W.; Cox, D.E.; Axe, J.D.

1991-01-01

A high resolution neutron powder diffractometer under construction at the Brookhaven HFBR is expected to be completed by mid-1991. The new machine will have a Ge (511) monochromator with a take-off angle of 120 o (λ=1.89A) and 64 3 He counters in the detector bank. There will be interchangeable collimators before the monochromator allowing a choice of 5 or 11' horizontal divergence, and 10 cm-high, 5' collimators in front of the detectors. In the higher resolution mode, Δd/d is expected to be about 6x10 -4 at the resolution minimum. The diffractometer is generally similar to D2B at the Institut Laue-Langevin except for the monochromator. This will consist of a vertically focussing array of segments 3x1.27 cm in dimensions cut from stacks of 20 0.43 mm wafers that have been pressed and brazed together. Preliminary measurements indicate that a mosaic width of 0.1-0.15 o and a peak reflectivity of 25% can be achieved in this way. (author) 2 figs., 22 refs

Practical considerations in the calculation of orientation distribution functions from electron back-scattered diffraction patterns

International Nuclear Information System (INIS)

Bowen, A.W.

1994-01-01

Using model data sets for the Brass orientation, the importance of scatter width, angular accuracy and grain size and volume fraction on the sensitivity of the calculated Orientation Distribution Functions have been determined in order to highlight some of the practical considerations needed in the processing of experimental data from individual grain orientation measurements determined by the Electron Back-Scattered Diffraction technique. It is suggested that the most appropriate scatter width can be calculated from the maximum function height versus scatter width curve in order to accommodate variations in texture sharpness. The sensitivity of the ODF to careful sample preparation, mounting and pattern analysis, in order to keep errors in angular accuracy to 1 or less is demonstrated, as is the imperative need to correct for the size of grains, and their volume fractions. (orig.)

Risk assessment and optimization (ALARA) analysis for the environmental remediation of Brookhaven National Laboratory`s hazardous waste management facility

Energy Technology Data Exchange (ETDEWEB)

Dionne, B.J.; Morris, S. III; Baum, J.W. [and others

1998-03-01

The Department of Energy`s (DOE) Office of Environment, Safety, and Health (EH) sought examples of risk-based approaches to environmental restoration to include in their guidance for DOE nuclear facilities. Extensive measurements of radiological contamination in soil and ground water have been made at Brookhaven National Laboratory`s Hazardous Waste Management Facility (HWMF) as part of a Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) remediation process. This provided an ideal opportunity for a case study. This report provides a risk assessment and an {open_quotes}As Low as Reasonably Achievable{close_quotes} (ALARA) analysis for use at other DOE nuclear facilities as an example of a risk-based decision technique.

Actor-Network Theory as a sociotechnical lens to explore the relationship of nurses and technology in practice: methodological considerations for nursing research.

Science.gov (United States)

Booth, Richard G; Andrusyszyn, Mary-Anne; Iwasiw, Carroll; Donelle, Lorie; Compeau, Deborah

2016-06-01

Actor-Network Theory is a research lens that has gained popularity in the nursing and health sciences domains. The perspective allows a researcher to describe the interaction of actors (both human and non-human) within networked sociomaterial contexts, including complex practice environments where nurses and health technology operate. This study will describe Actor-Network Theory and provide methodological considerations for researchers who are interested in using this sociotechnical lens within nursing and informatics-related research. Considerations related to technology conceptualization, levels of analysis, and sampling procedures in Actor-Network Theory based research are addressed. Finally, implications for future nursing research within complex environments are highlighted. © 2015 John Wiley & Sons Ltd.

16 CFR 1012.1 - General policy considerations; scope.

Science.gov (United States)

2010-01-01

... Policy, sets forth requirements for advance public notice, public attendance, and recordkeeping for... 16 Commercial Practices 2 2010-01-01 2010-01-01 false General policy considerations; scope. 1012.1 Section 1012.1 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL MEETINGS POLICY-MEETINGS...

Nevi and lasers: Practical considerations.

Science.gov (United States)

Rogers, Tova; Krakowski, Andrew C; Marino, Maria L; Rossi, Anthony; Anderson, Richard R; Marghoob, Ashfaq A

2018-01-01

Lasers are increasingly used for elective ablation of melanocytic nevi (MN). However, the associated risks of treating MN with lasers are debated and not well studied. Theoretical risks include inadvertently treating a melanoma mistaken for a nevus, the inability to remove all nevus cells and the possibility for residual cells to undergo malignant transformation, and the difficulty in clinically monitoring the remnant nevus for melanoma progression. Additional concerns include the morphological suitability of a lesion for laser removal and managing patients' expectations about the variable cosmetic outcomes. These potential issues have prompted us to outline some practical suggestions for clinicians and patients to consider when determining the suitability of a nevus for laser ablation. The choice to perform laser removal of a nevus is personal, both from the perspective of the treating physician and that of the person being treated. While acknowledging some uncertainty, we believe that these suggestions can help mitigate risk and improve patient outcomes. Lasers Surg. Med. 50:7-9, 2018. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Statistical considerations in practical contamination monitoring

International Nuclear Information System (INIS)

Brodsky, A.; Gallaghar, R.G.

1991-01-01

This paper reports on an examination of smear survey practices which indicates that many radiation safety programs are lacking in important aspects of contamination monitoring. In order to satisfy regulatory and potential litigatory requirements, smear surveys should include the measurement and recording of the flowing data: area of each smear and smear procedure (by reference); total counts on smear and counting procedure; total counts on appropriate blanks and description of blank; total counts on standard and specifications of standard; and all counting times. The rationale for these smear survey requirements is obtained by examining the formulation of the minimum detectable amount (MDA) on a smear

Consideration of climate change impacts and adaptation in EIA practice — Perspectives of actors in Austria and Germany

International Nuclear Information System (INIS)

Jiricka, Alexandra; Formayer, Herbert; Schmidt, Anna; Völler, Sonja; Leitner, Markus; Fischer, Thomas B.; Wachter, Thomas F.

2016-01-01

Current political discussions and developments indicate the importance and urgency of incorporating climate change considerations into EIA processes. The recent revision of the EU Directive 2014/52/EU on Environmental Impact Assessment (EIA) requires changes in the EIA practice of the EU member states. This paper investigates the extent to which the Environmental Impact Assessment (EIA) can contribute to an early consideration of climate change consequences in planning processes. In particular the roles of different actors in order to incorporate climate change impacts and adaptation into project planning subject to EIA at the appropriate levels are a core topic. Semi-structured expert interviews were carried out with representatives of the main infrastructure companies and institutions responsible in these sectors in Austria, which have to carry out EIA regularly. In a second step expert interviews were conducted with EIA assessors and EIA authorities in Austria and Germany, in order to examine the extent to which climate-based changes are already considered in EIA processes. This paper aims to discuss the different perspectives in the current EIA practice with regard to integrating climate change impacts as well as barriers and solutions identified by the groups of actors involved, namely project developers, environmental competent authorities and consultants (EIA assessors/practitioners). The interviews show that different groups of actors consider the topic to different degrees. Downscaling of climate change scenarios is in this context both, a critical issue with regards to availability of data and costs. Furthermore, assistance for the interpretation of relevant impacts, to be deducted from climate change scenarios, on the specific environmental issues in the area is needed. The main barriers identified by the EIA experts therefore include a lack of data as well as general uncertainty as to how far climate change should be considered in the process without

Consideration of climate change impacts and adaptation in EIA practice — Perspectives of actors in Austria and Germany

Energy Technology Data Exchange (ETDEWEB)

Jiricka, Alexandra, E-mail: alexandra.jiricka@boku.ac.at [University of Natural Resources and Applied Life Sciences, Vienna (Austria); Department of Landscape, Spatial and Infrastructure Sciences, Institute for Landscape Development, Recreation and Conservation Planning, Peter-Jordan-Straße 82, 1190 Vienna (Austria); Formayer, Herbert; Schmidt, Anna [University of Natural Resources and Applied Life Sciences, Vienna (Austria); Department of Landscape, Spatial and Infrastructure Sciences, Institute for Landscape Development, Recreation and Conservation Planning, Peter-Jordan-Straße 82, 1190 Vienna (Austria); Völler, Sonja; Leitner, Markus [Environment Agency Austria, Environmental Impact Assessment and Climate Change, Spittelauer Lände 5, 1090 Wien (Austria); Fischer, Thomas B. [Environmental Assessment and Management, School of Environmental Sciences, University of Liverpool, 74 Bedford Street South, Liverpool L69 7ZQ (United Kingdom); Wachter, Thomas F. [Büro für Umweltplanung Dr. Wachter, Wiesnerring 2c, Hamburg (Germany)

2016-02-15

Current political discussions and developments indicate the importance and urgency of incorporating climate change considerations into EIA processes. The recent revision of the EU Directive 2014/52/EU on Environmental Impact Assessment (EIA) requires changes in the EIA practice of the EU member states. This paper investigates the extent to which the Environmental Impact Assessment (EIA) can contribute to an early consideration of climate change consequences in planning processes. In particular the roles of different actors in order to incorporate climate change impacts and adaptation into project planning subject to EIA at the appropriate levels are a core topic. Semi-structured expert interviews were carried out with representatives of the main infrastructure companies and institutions responsible in these sectors in Austria, which have to carry out EIA regularly. In a second step expert interviews were conducted with EIA assessors and EIA authorities in Austria and Germany, in order to examine the extent to which climate-based changes are already considered in EIA processes. This paper aims to discuss the different perspectives in the current EIA practice with regard to integrating climate change impacts as well as barriers and solutions identified by the groups of actors involved, namely project developers, environmental competent authorities and consultants (EIA assessors/practitioners). The interviews show that different groups of actors consider the topic to different degrees. Downscaling of climate change scenarios is in this context both, a critical issue with regards to availability of data and costs. Furthermore, assistance for the interpretation of relevant impacts, to be deducted from climate change scenarios, on the specific environmental issues in the area is needed. The main barriers identified by the EIA experts therefore include a lack of data as well as general uncertainty as to how far climate change should be considered in the process without

Risk assessment and optimization (ALARA) analysis for the environmental remediation of Brookhaven National Laboratory`s hazardous waste management facility

Energy Technology Data Exchange (ETDEWEB)

Dionne, B.J.; Morris, S.C. III; Baum, J.W. [and others

1998-01-01

The Department of Energy`s (DOE) Office of Environment, Safety, and Health (EH) sought examples of risk-based approaches to environmental restoration to include in their guidance for DOE nuclear facilities. Extensive measurements of radiological contamination in soil and ground water have been made at Brookhaven National Laboratory`s Hazardous Waste Management Facility (HWMF) as part of a Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) remediation process. This provided an ideal opportunity for a case study. This report provides a risk assessment and an {open_quotes}As Low as Reasonably Achievable{close_quotes} (ALARA) analysis for use at other DOE nuclear facilities as an example of a risk-based decision technique. This document contains the Appendices for the report.

Upgrades of the epithermal neutron beam at the Brookhaven Medical Research Reactor

Energy Technology Data Exchange (ETDEWEB)

Liu, Hungyuan B.; Brugger, R.M.; Rorer, D.C.

1994-12-31

The first epithermal neutron beam at the Brookhaven Medical Research Reactor (BMRR) was installed in 1988 and produced a neutron beam that was satisfactory for the development of NCT with epithermal neutrons. This beam was used routinely until 1992 when the beam was upgraded by rearranging fuel elements in the reactor core to achieve a 50% increase in usable flux. Next, after computer modeling studies, it was proposed that the Al and Al{sub 2}O{sub 3} moderator material in the shutter that produced the epithermal neutrons could be rearranged to enhance the beam further. However, this modification was not started because a better option appeared, namely to use fission plates to move the source of fission neutrons closer to the moderator and the patient irradiation position to achieve more efficient moderation and production of epithermal neutrons. A fission plate converter (FPC) source has been designed recently and, to test the concept, implementation of this upgrade has started. The predicted beam parameters will be 12 x 10{sup 9} n{sub epi}/cm{sup 2}sec accompanying with doses from fast neutrons and gamma rays per epithermal neutron of 2.8 x 10{sup -11} and < 1 x 10{sup -11} cGycm{sup 2}/n, respectively, and a current-to-flux ratio of epithermal neutrons of 0.78. This conversion could be completed by late 1996.

Installation and testing of an optimized epithermal neutron beam at the Brookhaven Medical Research Reactor (BMRR)

Energy Technology Data Exchange (ETDEWEB)

Fairchild, R.G.; Kalef-Ezra, J.; Saraf, S.K.; Fiarman, S.; Ramsey, E.; Wielopolski, L.; Laster, B.; Wheeler, F. (Brookhaven National Lab., Upton, NY (USA); Ioannina Univ. (Greece); Brookhaven National Lab., Upton, NY (USA); State Univ. of New York, Stony Brook, NY (USA). Health Science Center; Brookhaven National Lab., Upton, NY (USA); EG and G Idaho, Inc., Idaho Falls, ID (USA))

1989-01-01

Various calculations indicate that an optimized epithermal neutron beam can be produced by moderating fission neutrons either with a combination of Al and D{sub 2}O, or with Al{sub 2}O{sub 3}. We have designed, installed and tested an Al{sub 2}O{sub 3} moderated epithermal neutron beam at the Brookhaven Medical Research Reactor (BMRR). The epithermal neutron fluence rate of 1.8 {times} 10{sup 9} n/cm{sup 2}-sec produces a peak thermal neutron fluence rate of 1.9 to 2.8 {times} 10{sup 9} n/cm{sup 2}-sec in a tissue equivalent (TE) phantom head, depending on the configuration. Thus a single therapy treatment of 5 {times} 10{sup 12} n/cm{sup 2} can be delivered in 30--45 minutes. All irradiation times are given for a BMRR power of 3 MW, which is the highest power which can be delivered continuously. 18 refs., 8 figs., 4 tabs.

[Revised practice guideline 'Anaemia in midwifery practice'

NARCIS (Netherlands)

Beentjes, M.; Jans, S.M.P.J.

2012-01-01

The practice guideline of the Royal Dutch Organization of Midwives 'Anaemia in primary care midwifery practice' published in 2000, has recently been revised. The revised guideline takes physiological haemodilution during pregnancy into consideration and provides gestation specific reference values

Implant-assisted removable partial dentures: practical considerations.

Science.gov (United States)

Omura, Aaron J; Latthe, Vaibhav; Marin, Mark M; Cagna, David R

2016-01-01

At the heart of prosthodontic treatment planning must be a sound understanding of the quality and reliability of the prosthodontic foundation. Implant prosthodontics relies almost entirely on the biological and mechanical properties of an osseous foundation. Initiation of therapy in the absence of a healthy and stable prosthodontic foundation risks unintended and suboptimal treatment outcomes. For conventional removable partial denture (RPD) therapy, consideration must be given to interactions between the soft and hard tissues available to support and stabilize planned prostheses. The strategic addition of implants to the partially edentulous foundation can improve the support, comfort, and esthetics of an RPD, resulting in elevated patient satisfaction and greater therapeutic success. This article discusses aspects of diagnosis, treatment planning, clinical management, laboratory execution, and maintenance that must be considered in order to obtain optimal results with implant-assisted RPDs.

Wildland Fire Management Plan for Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Green,T.

2009-10-23

This Wildland Fire Management Plan (FMP) for Brookhaven National Lab (BNL) updates the 2003 plan incorporating changes necessary to comply with DOE Order 450.1 and DOE P 450.4, Federal Wildland Fire Management Policy and Program Review; Wildland and Prescribed Fire Management Policy and implementation Procedures Reference Guide. This current plan incorporates changes since the original draft of the FMP that result from new policies on the national level. This update also removes references and dependence on the U.S. Fish & Wildlife Service and Department of the Interior, fully transitioning Wildland Fire Management responsibilities to BNL. The Department of Energy policy for managing wildland fires requires that all areas, managed by the DOE and/or its various contractors, that can sustain fire must have a FMP that details fire management guidelines for operational procedures associated with wild fire, operational, and prescribed fires. Fire management plans provide guidance on fire preparedness, fire prevention, wildfire suppression, and the use of controlled, 'prescribed' fires and mechanical means to control the amount of available combustible material. Values reflected in the BNL Wildland FMP include protecting life and public safety; Lab properties, structures and improvements; cultural and historical sites; neighboring private and public properties; and endangered, threatened, and species of concern. Other values supported by the plan include the enhancement of fire-dependent ecosystems at BNL. This FMP will be reviewed periodically to ensure the fire program advances and evolves with the missions of the DOE and BNL. This Fire Management Plan is presented in a format that coverers all aspects specified by DOE guidance documents which are based on the national template for fire management plans adopted under the National Fire Plan. The DOE is one of the signatory agencies on the National Fire Plan. This FMP is to be used and implemented for the

Practical design considerations for photovoltaic power station

Science.gov (United States)

Swanson, T. D.

Aspects of photovoltaic (PV) technology are discussed along with generic PV design considerations, taking into account the resource sunlight, PV modules and their reliability, questions of PV system design, the support structure subsystem, and a power conditioning unit subsystem. A description is presented of two recent projects which demonstrate the translation of an idea into actual working PV systems. A privately financed project in Denton, Maryland, went on line in early December, 1982, and began providing power to the local utility grid. It represents the first intermediate size, grid-connected, privately financed power station in the U.S. Based on firm quotes, the actual cost of this system is about $13/W peak. The other project, called the PV Breeder, is an energy independent facility which utilizes solar power to make new solar cells. It is also the first large industrial structure completely powered by the sun.

Advanced practice nurses: starting an independent practice.

Science.gov (United States)

Lambert, V A; Lambert, C E

1996-01-01

Independent or private practice is the delivery of nursing services provided by nurses over which nurses have full control. With a changing healthcare system, nurses are in a prime position to negotiate the delivery of appropriate, acceptable, and cost-effective health care as independent practitioners. This article addresses the mission and goals of independent practice, community need, business structure of the practice, housing the practice, legal considerations, financing the practice, marketing issues, clientele, record keeping, and reimbursement.

ACCELERATED SITE TECHNOLOGY DEPLOYMENT COST AND PERFORMANCE REPORT COMPARABILITY OF ISOCS INSTRUMENT IN RADIONUCLIDE CHARACTERICATION AT BROOKHAVEN NATIONAL LABORATORY

Energy Technology Data Exchange (ETDEWEB)

KALB,P.; LUCKETT,L.; MILLER,K.; GOGOLAK,C.; MILIAN,L.

2001-03-01

This report describes a DOE Accelerated Site Technology Deployment project being conducted at Brookhaven National Laboratory to deploy innovative, radiological, in situ analytical techniques. The technologies are being deployed in support of efforts to characterize the Brookhaven Graphite Research Reactor (BGRR) facility, which is currently undergoing decontamination and decommissioning. This report focuses on the deployment of the Canberra Industries In Situ Object Counting System (ISOCS) and assesses its data comparability to baseline methods of sampling and laboratory analysis. The battery-operated, field deployable gamma spectrometer provides traditional spectra of counts as a function of gamma energy. The spectra are then converted to radionuclide concentration by applying innovative efficiency calculations using monte carlo statistical methods and pre-defined geometry templates in the analysis software. Measurement of gamma emitting radionuclides has been accomplished during characterization of several BGRR components including the Pile Fan Sump, Above Ground Ducts, contaminated cooling fans, and graphite pile internals. Cs-137 is the predominant gamma-emitting radionuclide identified, with smaller quantities of Co-60 and Am-241 detected. The Project used the Multi-Agency Radiation Survey and Site Investigation Manual guidance and the Data Quality Objectives process to provide direction for survey planning and data quality assessment. Analytical results have been used to calculate data quality indicators (DQI) for the ISOCS measurements. Among the DQIs assessed in the report are sensitivity, accuracy, precision, bias, and minimum detectable concentration. The assessment of the in situ data quality using the DQIs demonstrates that the ISOCS data quality can be comparable to definitive level laboratory analysis when the field instrument is supported by an appropriate Quality Assurance Project Plan. A discussion of the results obtained by ISOCS analysis of

ACCELERATED SITE TECHNOLOGY DEPLOYMENT COST AND PERFORMANCE REPORT COMPARABILITY OF ISOCS INSTRUMENT IN RADIONUCLIDE CHARACTERICATION AT BROOKHAVEN NATIONAL LABORATORY

International Nuclear Information System (INIS)

KALB, P.; LUCKETT, L.; MILLER, K.; GOGOLAK, C.; MILIAN, L.

2001-01-01

This report describes a DOE Accelerated Site Technology Deployment project being conducted at Brookhaven National Laboratory to deploy innovative, radiological, in situ analytical techniques. The technologies are being deployed in support of efforts to characterize the Brookhaven Graphite Research Reactor (BGRR) facility, which is currently undergoing decontamination and decommissioning. This report focuses on the deployment of the Canberra Industries In Situ Object Counting System (ISOCS) and assesses its data comparability to baseline methods of sampling and laboratory analysis. The battery-operated, field deployable gamma spectrometer provides traditional spectra of counts as a function of gamma energy. The spectra are then converted to radionuclide concentration by applying innovative efficiency calculations using monte carlo statistical methods and pre-defined geometry templates in the analysis software. Measurement of gamma emitting radionuclides has been accomplished during characterization of several BGRR components including the Pile Fan Sump, Above Ground Ducts, contaminated cooling fans, and graphite pile internals. Cs-137 is the predominant gamma-emitting radionuclide identified, with smaller quantities of Co-60 and Am-241 detected. The Project used the Multi-Agency Radiation Survey and Site Investigation Manual guidance and the Data Quality Objectives process to provide direction for survey planning and data quality assessment. Analytical results have been used to calculate data quality indicators (DQI) for the ISOCS measurements. Among the DQIs assessed in the report are sensitivity, accuracy, precision, bias, and minimum detectable concentration. The assessment of the in situ data quality using the DQIs demonstrates that the ISOCS data quality can be comparable to definitive level laboratory analysis when the field instrument is supported by an appropriate Quality Assurance Project Plan. A discussion of the results obtained by ISOCS analysis of

Brookhaven National Laboratory site environmental report for calendar year 1993

International Nuclear Information System (INIS)

Naidu, J.R.; Royce, B.A.

1994-05-01

This report documents the results of the Environmental Monitoring Program at BNL and presents summary information about environmental compliance for 1993. To evaluate the effect of BNL operations on the local environment, measurements of direct radiation, and a variety of radionuclides and chemical compounds in ambient air, soil, sewage effluent, surface water, ground water and vegetation were made at the BNL site and at sites adjacent to the Laboratory. Brookhaven National Laboratory's compliance with all applicable guides, standards, and limits for radiological and nonradiological emissions to the environment were evaluated. Among the permitted facilities, two instances, of pH exceedances were observed at recharge basins, possible related to rain-water run-off to these recharge basins. Also, the discharge from the Sewage Treatment Plant (STP) to the Peconic River exceeded on five occasions, three for residual chlorine and one each for iron and ammonia nitrogen. The chlorine exceedances were related to a malfunctioning hypochlorite dosing pump and ceased when the pump was repaired. While the iron and ammonia-nitrogen could be the result of disturbances to the sand filter beds during maintenance. The environmental monitoring data has identified site-specific contamination of ground water and soil. These areas are subject to Remedial Investigation/Feasibility Studies (RI/FS) under the Inter Agency Agreement (IAG). Except for the above, the environmental monitoring data has continued to demonstrate that compliance was achieved with applicable environmental laws and regulations governing emission and discharge of materials to the environment, and that the environmental impacts at BNL are minimal and pose no threat to the public or to the environment. This report meets the requirements of DOE Orders 5484. 1, Environmental Protection, Safety, and Health Protection Information reporting requirements and 5400.1, General Environmental Protection Programs

Practical considerations and effects of metallic screen fluorescence and backscatter control in gamma computed radiography

International Nuclear Information System (INIS)

Mango, Steven

2016-01-01

It is a fairly common misconception that the role of metallic screens used with computed radiography is primarily that of scatter control, and that any amplification of the image signal is minimal. To the contrary, this paper shows how the physical interaction between gamma rays and front metallic screens can yield a significant boost in signal and whether that increased signal is, in fact, beneficial or detrimental to image quality. For rear metallic screens, this signal boost is differentiated from backscatter, and image quality considerations should be more carefully thought out because of the separation between the screen and the imaging layer provided by the imaging plate support. Various physical interactions are explained, and a series of practical experiments show the various changes in signal level and image quality with various thicknesses of lead and copper screens. Recommendations are made for the configuration of the imaging plate and screens for optimum image quality and for the control and monitoring of scatter.

PROJECT-SPECIFIC TYPE A VERIFICATION FOR THE HIGH FLUX BEAM REACTOR UNDERGROUND UTILITIES REMOVAL PHASE 2 D/F WASTE LINE REMOVAL, BROOKHAVEN NATIONAL LABORATORY UPTON, NEW YORK

International Nuclear Information System (INIS)

Weaver, P.C.

2010-01-01

Oak Ridge Institute for Science and Education (ORISE) has reviewed the project documentation and data for the High Flux Beam Reactor (HFBR) Underground Utilities removal Phase 2; the D/F Waste Line removal at Brookhaven National Laboratory (BNL) in Upton, New York. The Brookhaven Survey Group (BSG) has completed removal and performed the final status survey (FSS) of the D/F Waste Line that provided the conduit for pumping waste from Building 750 to Building 801. Sample results have been submitted as required to demonstrate that the cleanup goals of 15 mrem/yr above background to a resident in 50 years have been met. Four rounds of sampling, from pre-excavation to final status survey (FSS), were performed as specified in the Field Sampling Plan (FSP) (BNL 2010a). It is the policy of the US Departmental of Energy (DOE) to perform independent verifications of decontamination and decomissioning activities conducted at DOE facilities. ORISE has been designated as the organization responsible for this task at the HFBR. ORISE together with DOE determined that a Type A verification of the D/F Waste Line was appropriate based on its method of construction and upon the minimal potential for residual radioactivity in the area. The removal of underground utilities is being performed in three stages in the process to decommission the HFBR facility and support structures. Phase 2 of this project included the grouting and removal of 1100 feet of 2-inch pipe and 640 feet of 4-inch pipe that served as the D/F Waste Line. Based on the pre-excavation sample results of the soil overburden, the potential for contamination of the soil surrounding the pipe is minimal (BNL 2010a). ORISE reviewed the BNL FSP and identified comments for consideration (ORISE 2010). BNL prepared a revised FSP that addressed each ORISE comment adequately (BNL 2010a). ORISE referred to the revised Phase 2 D/F Waste Line removal FSP FSS data to conduct the Type A verification and determine whether the intent odf

Advanced R ampersand D for electron and photon beams at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Kirk, H.G.

1989-08-01

The Brookhaven Accelerator Test Facility consists of a 50-MeV linear accelerator and a laser system capable of generating short (a few picoseconds) laser pulses at both UV (266 nm) and infrared (10 μm) wavelengths. With these systems in place, the ATF has unique capabilities for the study of fundamental interactions between charged-particle beams and intense electromagnetic radiation. The principal research goals of the Accelerator Test Facility (ATF) axe the following. Laser Acceleration Program: We wig study the principles and techniques of particle acceleration at ultra-high frequencies (up to 30 THz) and with very high acceleration gradients (up to 1 GV/m). Production of Coherent Radiation: We wish to develop the next generation of photon sources with features like (a) short pulses (picoseconds or less), (b) coherence, and (c) high peak power. All of these attributes can be provided by free-electron lasers. High-brightness sources: A common denominator for the above programs is the need for electron beams with very small transverse and longitudinal emittances. We will devote a substantial amount of our resources to the production and understanding of electron beams that have these attributes. We will build advanced electron sources such as switched-power devices and rf guns with photocathodes. Important applications of this line of research include the development of high-luminosity linear colliders and free-electron lasers in the XUV regime

The RaDIATE High-Energy Proton Materials Irradiation Experiment at the Brookhaven Linac Isotope Producer Facility

Energy Technology Data Exchange (ETDEWEB)

Ammigan, Kavin; et al.

2017-05-01

The RaDIATE collaboration (Radiation Damage In Accelerator Target Environments) was founded in 2012 to bring together the high-energy accelerator target and nuclear materials communities to address the challenging issue of radiation damage effects in beam-intercepting materials. Success of current and future high intensity accelerator target facilities requires a fundamental understanding of these effects including measurement of materials property data. Toward this goal, the RaDIATE collaboration organized and carried out a materials irradiation run at the Brookhaven Linac Isotope Producer facility (BLIP). The experiment utilized a 181 MeV proton beam to irradiate several capsules, each containing many candidate material samples for various accelerator components. Materials included various grades/alloys of beryllium, graphite, silicon, iridium, titanium, TZM, CuCrZr, and aluminum. Attainable peak damage from an 8-week irradiation run ranges from 0.03 DPA (Be) to 7 DPA (Ir). Helium production is expected to range from 5 appm/DPA (Ir) to 3,000 appm/DPA (Be). The motivation, experimental parameters, as well as the post-irradiation examination plans of this experiment are described.

Dental considerations in cardiovascular patients: A practical perspective

Directory of Open Access Journals (Sweden)

Swantika Chaudhry

2016-07-01

Full Text Available Cardiovascular disease trends, complications, and associated therapeutics impact the dental health and treatment. Such patients require special consideration with regard to when and which dental treatment is appropriate and what precautions are required. Alertness to potential oral adverse drug reactions enables referral of patient's to his physician or cardiologist. Cardiovascular drugs are also known to have mild to potentially fatal drug interactions. Dental professionals may be the first line of defense in the detection and referral of a patient suspected of having cardiovascular disease, an uncontrolled disease status, or oral adverse drug reactions, and they have a key role to play in oral and systemic disease prevention and treatment, in partnership with the patient and his physician.

Design of small-animal thermal neutron irradiation facility at the Brookhaven Medical Research Reactor

International Nuclear Information System (INIS)

Liu, H.B.

1996-01-01

The broad beam facility (BBF) at the Brookhaven Medical Research Reactor (BMRR) can provide a thermal neutron beam with flux intensity and quality comparable to the beam currently used for research on neutron capture therapy using cell-culture and small-animal irradiations. Monte Carlo computations were made, first, to compare with the dosimetric measurements at the existing BBF and, second, to calculate the neutron and gamma fluxes and doses expected at the proposed BBF. Multiple cell cultures or small animals could be irradiated simultaneously at the so-modified BBF under conditions similar to or better than those individual animals irradiated at the existing thermal neutron irradiation Facility (TNIF) of the BMRR. The flux intensity of the collimated thermal neutron beam at the proposed BBF would be 1.7 x 10 10 n/cm 2 ·s at 3-MW reactor power, the same as at the TNIF. However, the proposed collimated beam would have much lower gamma (0.89 x 10 -11 cGy·cm 2 /n th ) and fast neutron (0.58 x 10 -11 cGy·cm 2 /n th ) contaminations, 64 and 19% of those at the TNIF, respectively. The feasibility of remodeling the facility is discussed

Practicing uneven age management: does it pay? Some economic considerations

Science.gov (United States)

Gary W. Miller

1991-01-01

Unevenage silvicultural practices can be used to regenerate and manage many eastern hardwood stands. Single-tree cutting methods are feasible in stands where a desirable shade tolerant commercial species can be regenerated following periodic harvests. A variety of partial harvest practices, including single-tree selection and diameterlimit cutting have been used for 30...

Workshop: Linac90

Energy Technology Data Exchange (ETDEWEB)

Van Dyck, Olin

1990-12-15

In 1960 the first linear accelerator (linac) conference was organized at Brookhaven by John Blewett. In the few years following, linear accelerator energies jumped from 50 MeV (at Brookhaven and CERN) to 2 GeV at Stanford. With the realization that, at least for electrons, circular accelerators have reached their practical limits, linacs are once more in the spotlight.

Workshop: Linac90

International Nuclear Information System (INIS)

Van Dyck, Olin

1990-01-01

In 1960 the first linear accelerator (linac) conference was organized at Brookhaven by John Blewett. In the few years following, linear accelerator energies jumped from 50 MeV (at Brookhaven and CERN) to 2 GeV at Stanford. With the realization that, at least for electrons, circular accelerators have reached their practical limits, linacs are once more in the spotlight

Natural Resource Management Plan for Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

green, T.

2011-08-15

This comprehensive Natural Resource Management Plan (NRMP) for Brookhaven National Laboratory (BNL) was built on the successful foundation of the Wildlife Management Plan for BNL, which it replaces. This update to the 2003 plan continues to build on successes and efforts to better understand the ecosystems and natural resources found on the BNL site. The plan establishes the basis for managing the varied natural resources located on the 5,265 acre BNL site, setting goals and actions to achieve those goals. The planning of this document is based on the knowledge and expertise gained over the past 10 years by the Natural Resources management staff at BNL in concert with local natural resource agencies including the New York State Department of Environmental Conservation, Long Island Pine Barrens Joint Planning and Policy Commission, The Nature Conservancy, and others. The development of this plan is an attempt at sound ecological management that not only benefits BNL's ecosystems but also benefits the greater Pine Barrens habitats in which BNL is situated. This plan applies equally to the Upton Ecological and Research Reserve (Upton Reserve). Any difference in management between the larger BNL area and the Upton Reserve are noted in the text. The purpose of the Natural Resource Management Plan (NRMP) is to provide management guidance, promote stewardship of the natural resources found at BNL, and to sustainably integrate their protection with pursuit of the Laboratory's mission. The philosophy or guiding principles of the NRMP are stewardship, sustainability, adaptive ecosystem management, compliance, integration with other plans and requirements, and the incorporation of community involvement, where applicable. The NRMP is periodically reviewed and updated, typically every five years. This review and update was delayed to develop documents associated with a new third party facility, the Long Island Solar Farm. This two hundred acre facility will result in

Practical considerations for obtaining high quality quantitative computed tomography data of the skeletal system.

Science.gov (United States)

Troy, Karen L; Edwards, W Brent

2018-05-01

Quantitative CT (QCT) analysis involves the calculation of specific parameters such as bone volume and density from CT image data, and can be a powerful tool for understanding bone quality and quantity. However, without careful attention to detail during all steps of the acquisition and analysis process, data can be of poor- to unusable-quality. Good quality QCT for research requires meticulous attention to detail and standardization of all aspects of data collection and analysis to a degree that is uncommon in a clinical setting. Here, we review the literature to summarize practical and technical considerations for obtaining high quality QCT data, and provide examples of how each recommendation affects calculated variables. We also provide an overview of the QCT analysis technique to illustrate additional opportunities to improve data reproducibility and reliability. Key recommendations include: standardizing the scanner and data acquisition settings, minimizing image artifacts, selecting an appropriate reconstruction algorithm, and maximizing repeatability and objectivity during QCT analysis. The goal of the recommendations is to reduce potential sources of error throughout the analysis, from scan acquisition to the interpretation of results. Copyright © 2018 Elsevier Inc. All rights reserved.

Practical considerations in clinical strategy to support the development of injectable drug-device combination products for biologics.

Science.gov (United States)

Li, Zhaoyang; Easton, Rachael

2018-01-01

The development of an injectable drug-device combination (DDC) product for biologics is an intricate and evolving process that requires substantial investments of time and money. Consequently, the commercial dosage form(s) or presentation(s) are often not ready when pivotal trials commence, and it is common to have drug product changes (manufacturing process or presentation) during clinical development. A scientifically sound and robust bridging strategy is required in order to introduce these changes into the clinic safely. There is currently no single developmental paradigm, but a risk-based hierarchical approach has been well accepted. The rigor required of a bridging package depends on the level of risk associated with the changes. Clinical pharmacokinetic/pharmacodynamic comparability or outcome studies are only required when important changes occur at a late stage. Moreover, an injectable DDC needs to be user-centric, and usability assessment in real-world clinical settings may be required to support the approval of a DDC. In this review, we discuss the common issues during the manufacturing process and presentation development of an injectable DDC and practical considerations in establishing a clinical strategy to address these issues, including key elements of clinical studies. We also analyze the current practice in the industry and review relevant and status of regulatory guidance in the DDC field.

Epithermal beam development at the BMRR [Brookhaven Medical Research Reactor]: Dosimetric evaluation

International Nuclear Information System (INIS)

Saraf, S.K.; Fairchild, R.G.; Kalef-Ezra, J.; Laster, B.H.; Fiarman, S.; Ramsey, E.; Ioannina Univ.; Brookhaven National Lab., Upton, NY; State Univ. of New York, Stony Brook, NY

1989-01-01

The utilization of an epithermal neutron beam for neutron capture therapy (NCT) is desirable because of the increased tissue penetration relative to a thermal neutron beam. Over the past few years, modifications have been and continue to be made at the Brookhaven Medical Research Reactor (BMRR) by changing its filter components to produce an optimal epithermal beam. An optimal epithermal beam should contain a low fast neutron contamination and no thermal neutrons in the incident beam. Recently a new moderator for the epithermal beam has been installed at the epithermal port of the BMRR and has accomplished this task. This new moderator is a combination of alumina (Al 2 O 3 ) bricks and aluminum (Al) plates. A 0.51 mm thick cadmium (Cd) sheet has reduced the thermal neutron intensity drastically. Furthermore, an 11.5 cm thick bismuth (Bi) plate installed at the port surface has reduced the gamma dose component to negligible levels. Foil activation techniques have been employed by using bare gold and cadmium-covered gold foil to determine thermal as well as epithermal neutron fluence. Fast neutron fluence has been determined by indium foil counting. Fast neutron and gamma dose in soft tissue, free in air, is being determined by the paired ionization chamber technique, using tissue equivalent (TE) and graphite chambers. Thermoluminescent dosimeters (TLD-700) have also been used to determine the gamma dose independently. This paper describes the methods involved in the measurements of the above mentioned parameters. Formulations have been developed and the various corrections involved have been detailed. 12 refs

Ethical considerations of therapeutic hypnosis and children.

Science.gov (United States)

Etzrodt, Christine M

2013-04-01

Historically, therapeutic hypnosis has been met with skepticism within some fields, although acceptance has expanded in recent decades. Development and application of ethical standards and principles has contributed to increased acceptance of hypnosis with children. The Ethics Code of the American Psychological Association (APA, 2002) and the Code of Conduct of the American Society of Clinical Hypnosis (ASCH, 2000) serve as guides to ethical considerations when treating children. From a developmental and practical perspective, children have limited decision-making capacities, therefore special attention should be paid to their rights and welfare. Important ethical considerations relevant to children and hypnosis have emerged, including competence, supervision, informed consent, confidentiality, and boundaries. Considerations are reviewed from a normal and abnormal child development perspective.

Measuring energy metabolism in the mouse – theoretical, practical and analytical considerations

Directory of Open Access Journals (Sweden)

John Roger Speakman

2013-03-01

Full Text Available The mouse is one of the most important model organisms for understanding human genetic function and disease. This includes characterisation of the factors that influence energy expenditure and dysregulation of energy balance leading to obesity and its sequalae. Measuring energy metabolism in the mouse presents a challenge because the animals are small, and in this respect it presents similar challenges to measuring energy demands in many other species of small mammal. This paper considers some theoretical, practical and analytical considerations to be considered when measuring energy expenditure in mice. Theoretically total daily energy expenditure is comprised of several different components: basal or resting expenditure, physical activity, thermoregulation and the thermic effect of food. Energy expenditure in mice is normally measured using open flow indirect calorimetry apparatus. Two types of system are available – one of which involves a single small Spartan chamber linked to a single analyser, which is ideal for measuring the individual components of energy demand. The other type of system involves a large chamber which mimics the home cage environment and is generally configured with several chambers per analyser. These latter systems are ideal for measuring total daily energy expenditure but at present do not allow accurate decomposition of the total expenditure into its components. The greatest analytical challenge for mouse expenditure data is how to account for body size differences between individuals. This has been a matter of some discussion for at least 120 years. The statistically most appropriate approach is to use ANCOVA with individual aspects of body composition as independent predictors.

Exceptions to the Stark law: practical considerations for surgeons.

Science.gov (United States)

Satiani, Bhagwan

2006-03-01

The purpose of this study was to provide an understanding of the applicable legislative exceptions to prohibitions under the Stark law, which governs common legitimate business relationships in surgical practice. Stark I and II prohibits all referrals (and claims) for the provision of designated health services for federal reimbursement if a physician or immediate family member has any financial relationship with the entity. Regardless of intent (unlike the antikickback statute), any financial relationship is illegal unless specifically excepted by statute. These exceptions are relevant to ownership, compensation arrangements, or both. The most important ones relevant to surgeons are as follows: physician service exception (services rendered in an intragroup referral); in-office ancillary services exception (office-based vascular laboratory); the whole hospital exception (ownership interest in a hospital or department); lease exception (conditions that must be met for a lease not to be considered illegal); bona fide employment exception (important to academic medical centers); personal services arrangement exception (vascular laboratory medical directorship); physician incentive plans exception (if volume or value of referrals are an issue); hospital-affiliated group practice exception (physician services billed by a hospital); recruitment arrangement exception (inducements by hospitals to relocate); items/services exception (transcription services purchased from a hospital); fair market value exception (covers services provided to health care entities); indirect compensation arrangements (dealings between a hospital and entity owned by physicians); and academic medical centers exception (new phase II rules broaden the definition of academic medical centers and ease the requirement that practice plans be tax-exempt organizations, among other changes. Although expert legal advice is required for navigation through the maze of Stark laws, it is incumbent on surgeons

Analytical Frameworks of Cooperative and Cognitive Radio Systems with Practical Considerations

KAUST Repository

Khan, Fahd Ahmed

2013-08-01

the performance of a network where two sources communicate with each other via fixed-gain amplify-and-forward relays is studied and for a Rayleigh faded channel, closed-form expressions for the outage probability (OP), moment generating function (MGF) and SER are derived. Relay location is also taken into consideration and it is shown that the performance can be improved by placing the relay closer to the source whose channel is more outdated. Some practical issues encountered in cognitive radio systems (CRS) are also investigated. The QoS of CRS can be improved through spatial diversity which can be achieved by either using multiple antennas or exploiting the independent channels of each user in a multi-user network. In this dissertation, both approaches are examined and in multi-antenna CRS, transmit antenna selection (TAS) is proposed where as in a multi-user CRS, user selection is proposed to achieve performance gains. TAS reduces the implementation cost and complexity and thus makes CRS more feasible. Additionally, unlike previous works, in accordance with real world systems, the transmitter is assumed to have limited peak transmit power. For both these schemes, considering practical channel models, closed-form expression for the OP performance, SER performance and ergodic capacity (EC) are obtained and the performance in the asymptotic regimes is also studied. Furthermore, the OP performance is also analyzed taking into account the interference from the primary network on the cognitive network.

Practical considerations in clinical strategy to support the development of injectable drug-device combination products for biologics

Science.gov (United States)

Easton, Rachael

2018-01-01

ABSTRACT The development of an injectable drug-device combination (DDC) product for biologics is an intricate and evolving process that requires substantial investments of time and money. Consequently, the commercial dosage form(s) or presentation(s) are often not ready when pivotal trials commence, and it is common to have drug product changes (manufacturing process or presentation) during clinical development. A scientifically sound and robust bridging strategy is required in order to introduce these changes into the clinic safely. There is currently no single developmental paradigm, but a risk-based hierarchical approach has been well accepted. The rigor required of a bridging package depends on the level of risk associated with the changes. Clinical pharmacokinetic/pharmacodynamic comparability or outcome studies are only required when important changes occur at a late stage. Moreover, an injectable DDC needs to be user-centric, and usability assessment in real-world clinical settings may be required to support the approval of a DDC. In this review, we discuss the common issues during the manufacturing process and presentation development of an injectable DDC and practical considerations in establishing a clinical strategy to address these issues, including key elements of clinical studies. We also analyze the current practice in the industry and review relevant and status of regulatory guidance in the DDC field. PMID:29035675

Dedicated search for the time evolution of an electron neutrino beam at the Brookhaven AGS

International Nuclear Information System (INIS)

Bionta, R.; LoSecco, J.; Ong, R.; Stone, J.; Sulak, L.; Watts, R.; Cortez, B.; Foster, G.W.

1981-01-01

An experiment dedicated to the study of the time evolution of a neutrino beam enriched with ν/sub e/'s is suggested as feasible. It appears that the highest fluxes can be achieved with current beam lines at the Brookhaven AGS or the CERN PS. A configuration optimized for good sensitivity to neutrino eigenmass differences from 1 eV to 20 eV and mixing (Pontecorvo) angles down to 15 0 (comparable to the Cabibbo angle) is considered. The ν/sub e/ beam is formed using K/sub e3/ 0 decays. A simultaneously produced ν/sub μ/ beam from K/sub μ3/ 0 decay serves as the normalizer. Pion generated ν/sub μ/'s are suppressed to limit background. A massive detector is employed to obtain sufficient statistical power. It consists of a series of seven water Cerenkov modules (each with 180T fiducial mass), judiciously spaced along the ν line to provide flight paths from 40 m to 1000 m. The detector elements duplicate a recently developed technology that is eminently suited to this investigation. Simulation and reconstruction of neutrino events in a detector similar to the one suggested show sufficient resolution in angle, energy, position and event timing relative to the beam

RHIC and quark matter: proposal for a relativistic heavy ion collider at Brookhaven National Laboratory

International Nuclear Information System (INIS)

1984-08-01

This document describes the Brookhaven National Laboratory Proposal for the construction of a Relativistic Heavy Ion Collider (RHIC). The construction of this facility represents the natural continuation of the laboratory's role as a center for nuclear and high-energy physics research and extends and uses the existing AGS, Tandem Van de Graaff and CBA facilities at BNL in a very cost effective manner. The Administration and Congress have approved a project which will provide a link between the Tandem Van de Graaf and the AGS. Completion of this project in 1986 will provide fixed target capabilities at the AGS for heavy ions of about 14 GeV/amu with masses up to approx. 30 (sulfur). The addition of an AGS booster would extend the mass range to the heaviest ions (A approx. 200, e.g., gold); its construction could start in 1986 and be completed in three years. These two new AGS experimental facilities can be combined with the proposed Relativistic Heavy Ion Collider to extend the energy range to 100 x 100 GeV/amu for the heaviest ions. BNL proposes to start construction of RHIC in FY 86 with completion in FY 90 at a total cost of 134 M$

Ideology and community social psychology: theoretical considerations and practical implications.

Science.gov (United States)

Montenegro, Marisela

2002-08-01

This paper addresses the importance of the concept of ideology in community work. The implications of a Marxist approach to ideology in community practice are analyzed in terms of the concepts of problematization (P. Freire, 1979) and consciousness-raising (J. Barreiro, 1976), illustrating the point with some examples. The traditional Marxist perspective is also examined in relation to the perspectives of social constructionism (I. Ibáñez, 1996), cultural studies (A. McRobbie, 1992), post-Marxism (E. Laclau & C. Mouffe, 1985), and feminism (D. Haraway, 1991). It is argued that the concepts of hegemony and habitus (P. Bourdieu, 1985) can be useful to community social psychology theory and practice. A "situated perspective"--in which it is possible to dialogue from different "subject positions," and articulate transformation and political action--is argued. The implications of this shifting in the concept of ideology by means of theoretical developments outside social communitypsychology can help to define the external (outside) agent's position in community practice.

Technical note - Considerations for MR imaging of small animals

International Nuclear Information System (INIS)

Baker, Martin A.

2011-01-01

Routine clinical veterinary use of MR scanning is becoming more common. This article addresses the major technical considerations for radiographers performing MR examinations on small animals and provides practical advice for scanning techniques.

Practical considerations in radionuclide imaging of pediatric patients

International Nuclear Information System (INIS)

Conway, J.J.

1984-01-01

A certain proportion of the patients encountered in the practice of nuclear medicine will fall within the pediatric age group. The pediatric age range is usually defined as extending from birth to 18 years. Therefore, the specialist in nuclear medicine may have to deal with pediatric patients weighing as little as 800 g or as much as 300 lb. This encounter may be pleasant or unpleasant, depending upon the physician's knowledge of the techniques required for handling children and obtaining an adequate study and a basic understanding of specific pediatric disorders. Among the issues that must be considered are the equipment, which must be suitable for handling and obtaining optimal images of small children; the development of a basic understanding of the peculiarities of radiopharmaceutical distribution in children, which differs from that in adults; and, importantly, a knowledge of radiation dosimetry as it relates to the pediatric patient. It is beyond the scope of this chapter to present a comprehensive dissertation on the topic of pediatric nuclear medicine. The theme therefore is limited to the general principles and techniques required for nuclear medicine studies on pediatric patients. In addition, studies that exhibit unique characteristics when performed on children are highlighted in an effort to define that essence of pediatric nuclear medicine that differentiates it from the practice of nuclear medicine in adults

Special Consideration in Post-Secondary Institutions: Trends at a Canadian University

Science.gov (United States)

Zimmermann, Joelle; Kamenetsky, Stuart B.; Pongracic, Syb

2015-01-01

This study examined trends in the practice of granting special consideration for missed tests and late papers in colleges and universities. We analyzed a database of 4,183 special consideration requests at a large Canadian university between 1998 and 2008. Results show a growing rate of requests per enrolment between 2001 and 2007. Although…

Cathode cooling systems for the magnetron and Penning H- sources: a progress report of work at Brookhaven National Laboratory

International Nuclear Information System (INIS)

McKenzie-Wilson, R.B.

1977-01-01

The magnetron/Penning H - sources being developed at Brookhaven National Laboratory have produced ion currents up to 1 A with pulse lengths of 10 ms. The pulse length is limited by heating of the cathode surface. Cathode thermal conditions were investigated and lead to the conclusion that a cathode cooling system must be capable of handling 3 kW cm -2 of heated cathode surface. A review of cooling fluid requirements coupled with an examination of possible cooling fluids, leads to the conclusion that demineralized water is a suitable cooling fluid when used under pressurized nucleated boiling conditions. A correlation is used to show that heat-flux of 1.25 kW cm -2 could be removed using current technology and that this heat flux may be extended to 3 kW cm -2 by use of the Hyper-Vapotron effect. The temperature of the working surface of the cathode may be varied over a small temperature range by varying the system pressure during operation

Dynamic design matter[s] : Practical considerations for interactive architecture

NARCIS (Netherlands)

Jaskiewicz, T.

2008-01-01

This paper explores the concept of interactive architecture. The first section begins by formulating a daring vision of a radically new kind of architecture. In the second chapter this vision is further elaborated upon, by proposing a generic approach towards practically accomplishing the originally

Ethical Considerations in College Admission Practices: A Proposal for Dialogic Involvement.

Science.gov (United States)

Gallagher, Victoria

1992-01-01

Notes that current surge in promotional activities has called into question the social responsibility of colleges and universities. Focuses specifically on admission and promotional practices. Begins by reviewing the current practice, then goes on to discuss self-regulation, counseling, and the role of marketing in the college admission process.…

Practical considerations in planning a cath-lab | Schulenburg | SA ...

African Journals Online (AJOL)

Planning a vascular laboratory depends on various factors like the geographic environment of the radiology practice, the need for interventional procedures, types of angiography procedures, the number of patients, building size, and lastly the budget available for equipment and running costs. Usually the suppliers of the ...

Practical considerations in realizing a magnetic centrifugal mass filter

Energy Technology Data Exchange (ETDEWEB)

Gueroult, Renaud; Fisch, Nathaniel J. [Princeton Plasma Physics Laboratory, Princeton University, Princeton, New Jersey 08543 (United States)

2012-12-15

The magnetic centrifugal mass filter concept represents a variation on the plasma centrifuge, with applications that are particularly promising for high-throughput separation of ions with large mass differences. A number of considerations, however, constrain the parameter space in which this device operates best. The rotation speed, magnetic field intensity, and ion temperature are constrained by the ion confinement requirements. Collisions must also be large enough to eject ions, but small enough not to eject them too quickly. The existence of favorable regimes meeting these constraints is demonstrated by a single-particle orbit code. As an example of interest, it is shown that separation factors of about 2.3 are achievable in a single pass when separating Aluminum from Strontium ions.

Ethical Issues and Best Practice Considerations for Internet Research

Science.gov (United States)

Colvin, Jan; Lanigan, Jane

2005-01-01

With rapidly increasing public use of the Internet and advances in Web technologies, family and consumer sciences researchers have the opportunity to conduct Internet-based research. However, online research raises critical ethical issues concerning human subjects that have an impact on research practices. This article provides a review of the…

Clinical and practical considerations in the pharmacologic management of narcolepsy.

Science.gov (United States)

Thorpy, Michael J; Dauvilliers, Yves

2015-01-01

Despite published treatment recommendations and the availability of approved and off-label pharmacologic therapies for narcolepsy, the clinical management of this incurable, chronic neurologic disorder remains challenging. While treatment is generally symptomatically driven, decisions regarding which drug(s) to use need to take into account a variety of factors that may affect adherence, efficacy, and tolerability. Type 1 narcolepsy (predominantly excessive daytime sleepiness with cataplexy) or type 2 narcolepsy (excessive daytime sleepiness without cataplexy) may drive treatment decisions, with consideration given either to a single drug that targets multiple symptoms or to multiple drugs that each treat a specific symptom. Other drug-related characteristics that affect drug choice are dosing regimens, tolerability, and potential drug-drug interactions. Additionally, the patient should be an active participant in treatment decisions, and the main symptomatic complaints, treatment goals, psychosocial setting, and use of lifestyle substances (ie, alcohol, nicotine, caffeine, and cannabis) need to be discussed with respect to treatment decisions. Although there is a lack of narcolepsy-specific instruments for monitoring therapeutic effects, clinically relevant subjective and objective measures of daytime sleepiness (eg, Epworth Sleepiness Scale and Maintenance of Wakefulness Test) can be used to provide guidance on whether treatment goals are being met. These considerations are discussed with the objective of providing clinically relevant recommendations for making treatment decisions that can enhance the effective management of patients with narcolepsy. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

Practical considerations in the design and operation of superconducting structures

International Nuclear Information System (INIS)

Schwettman, H.A.

1975-01-01

During the past few years, considerable experience has been gained in the operation of prototype superconducting accelerators under beam line conditions. As a result of this experience, important aspects of structure design and important questions related to the long term operation of superconducting structures have been brought into sharper focus. For applications where low power loss and high duty factor, or exceptional beam quality and stable operation, are essential properties, and where modest energy gradients can be tolerated, superconducting structures are distinctly superior to conventional room temperature structures. (auth)

Epigenetic considerations in aquaculture

Directory of Open Access Journals (Sweden)

Mackenzie R. Gavery

2017-12-01

Full Text Available Epigenetics has attracted considerable attention with respect to its potential value in many areas of agricultural production, particularly under conditions where the environment can be manipulated or natural variation exists. Here we introduce key concepts and definitions of epigenetic mechanisms, including DNA methylation, histone modifications and non-coding RNA, review the current understanding of epigenetics in both fish and shellfish, and propose key areas of aquaculture where epigenetics could be applied. The first key area is environmental manipulation, where the intention is to induce an ‘epigenetic memory’ either within or between generations to produce a desired phenotype. The second key area is epigenetic selection, which, alone or combined with genetic selection, may increase the reliability of producing animals with desired phenotypes. Based on aspects of life history and husbandry practices in aquaculture species, the application of epigenetic knowledge could significantly affect the productivity and sustainability of aquaculture practices. Conversely, clarifying the role of epigenetic mechanisms in aquaculture species may upend traditional assumptions about selection practices. Ultimately, there are still many unanswered questions regarding how epigenetic mechanisms might be leveraged in aquaculture.

[Innovative Prenatal Testing: Clinical Applications and Ethical Considerations].

Science.gov (United States)

Huang, Mei-Chih; Lin, Shio-Jean; Chen, Chih-Ling; Huang, Tzu-Jung

2017-10-01

The biomedical technology related to prenatal screen/diagnosis has developed rapidly in recent decades. Many prenatal genetic examinations are now available to assist pregnant women to better understand the status and development of their fetus. Moreover, many commercial advertisements for innovative prenatal examinations are now shown in the media. Cell-free DNA Screening (cfDNA screening), a non-invasive prenatal testing (NIPT) procedure, is a safe and high accuracy test that may be done at an earlier gestational age to screen for fetal aneuploidy. The following questions should be considered when applying cfDNA screening in clinical practice: 1. what is cfDNA screening, 2. who are its potential users, and 3. what ethical and policy considerations are associated with this examination? This article provides relevant information, clinical practice guidelines, and ethical / policy considerations related to cfDNA screening. Discussing cases involving different clinical situations helps promote understanding of cfDNA screening and maternal-care quality.

Telecommuting: Occupational health considerations for employee health and safety.

Science.gov (United States)

Healy, M L

2000-06-01

1. Information technology has moved "work" out of a centralized location. Employees who telecommute pose significant challenges and considerations for the practice of occupational health nursing. 2. Employer and employee benefits associated with telecommuting are reportedly associated with high levels of job satisfaction. However, the occupational health and safety risks of this new work environment need to be fully assessed and understood. 3. The ergonomic controls to minimize the risk of repetitive motion injuries are the same for both office and home locations. Additional attention need to be paid to implementing risk controls for other physical hazards and psychosocial considerations, as well as personal safety and security issues. 4. The scope of occupational health nursing practice needs to remain dynamic, recognizing the impact new technologies have on the workplace, to continue to meet the needs of the changing workplace.

Aerial radiological survey of the Shoreham Nuclear Power Station and surrounding area Brookhaven, New York

International Nuclear Information System (INIS)

1984-03-01

An aerial radiological survey was performed over the area surrounding the Shoreham Nuclear Power Station during 5 to 9 June 1983. The survey, which covered an area of 338 square kilometers (131 square miles), also encompassed the entire Brookhaven National Laboratory (BNL) facility. The highest radiation exposure rate, over 1 milliroentgen per hour (mR/h), was inferred from data measured directly over the BNL facility. This detected activity was due to the presence of cobalt-58, cobalt-60 and cesium-137, which was consistent with normal BNL operations. With the exception of the BNL facility, the only detected man-made radioactivity was found near a cottage in Moriches, New York and was due to the presence of cobalt-60. For the remainder of the survey area, the inferred radiation exposure rates varied generally from 6 to 12 microroentgens per hour (μR/h). The reported exposure rate values include an estimated cosmic ray contribution of 3.7 μR/h. Ground-based measurements, conducted concurrently with the aerial survey, were compared to the inferred aerial results. Pressurized ionization chamber readings and a group of soil samples were acquired from five locations within the survey area. The exposure rate values obtained from these measurements were consistent with those inferred from the aerial results. 11 references, 12 figures, 3 tables

PROJECT-SPECIFIC TYPE A VERIFICATION FOR THE HIGH FLUX BEAM REACTOR UNDERGROUND UTILITIES REMOVAL PHASE 3 TRENCH 5, BROOKHAVEN NATIONAL LABORATORY UPTON, NEW YORK

International Nuclear Information System (INIS)

Weaver, P.C.

2010-01-01

The Oak Ridge Institute for Science and Education (ORISE) has reviewed the project documentation and data for the High Flux Beam Reactor (HFBR) Underground Utilities removal Phase 3; Trench 5 at Brookhaven National Laboratory (BNL) in Upton, New York. The Brookhaven Survey Group (BSG) has completed removal and performed Final Status Survey (FSS) of the concrete duct from Trench 5 from Building 801 to the Stack. Sample results have been submitted as required to demonstrate that the cleanup goal of (le)15 mrem/yr above background to a resident in 50 years has been met. Four rounds of sampling, from pre-excavation to FSS, were performed as specified in the Field Sampling Plan (FSP) (BNL 2010a). It is the policy of the U.S. Department of Energy (DOE) to perform independent verifications of decontamination and decommissioning activities conducted at DOE facilities. ORISE has been designated as the organization responsible for this task for the HFBR Underground Utilities. ORISE, together with DOE, determined that a Type A verification of Trench 5 was appropriate based on recent verification results from Trenches 2, 3, and 4, and the minimal potential for residual radioactivity in the area. The removal of underground utilities is being performed in three stages to decommission the HFBR facility and support structures. Phase 3 of this project included the removal of at least 200 feet of 36-inch to 42-inch pipe from the west side to the south side of Building 801, and the 14-inch diameter Acid Waste Line that spanned from 801 to the Stack within Trench 5. Based on the pre-excavation sample results of the soil overburden the potential for contamination of the soil surrounding the pipe is minimal (BNL 2010a). ORISE reviewed the BNL FSP and identified comments for consideration (ORISE 2010). BNL prepared a revised FSP that resolved each ORISE comment adequately (BNL 2010a). ORISE referred to the revised HFBR Underground Utilities FSP FSS data to conduct the Type A verification

THEORETICAL AND PRACTICAL CONSIDERATIONS REGARDING THE COST CALCULATION USING DIRECT COSTING

Directory of Open Access Journals (Sweden)

Cristina Aurora, Bunea-Bontaş

2012-01-01

Full Text Available The definition of the cost of production as applied to inventories refers to the acquisition and production cost, and its determination involves many considerations. This article emphasizes a comparative approach of the calculation of production cost under direct costing and absorption costing, and examines the impact of using these calculation systems on the financial performance of the companies presented in the income statement.

Euthanasia of Cattle: Practical Considerations and Application.

Science.gov (United States)

Shearer, Jan Keith

2018-04-17

Acceptable methods for the euthanasia of cattle include overdose of an anesthetic, gunshot and captive bolt. The use of anesthetics for euthanasia is costly and complicates carcass disposal. These issues can be avoided by use of a physical method such as gunshot or captive bolt; however, each requires that certain conditions be met to assure an immediate loss of consciousness and death. For example, the caliber of firearm and type of bullet are important considerations when gunshot is used. When captive bolt is used, a penetrating captive bolt loaded with the appropriate powder charge and accompanied by a follow up (adjunctive) step to assure death are required. The success of physical methods also requires careful selection of the anatomic site for entry of a “free bullet” or “bolt” in the case of penetrating captive bolt. Disease eradication plans for animal health emergencies necessitate methods of euthanasia that will facilitate rapid and efficient depopulation of animals while preserving their welfare to the greatest extent possible. A portable pneumatic captive bolt device has been developed and validated as effective for use in mass depopulation scenarios. Finally, while most tend to focus on the technical aspects of euthanasia, it is extremely important that no one forget the human cost for those who may be required to perform the task of euthanasia on a regular basis. Symptoms including depression, grief, sleeplessness and destructive behaviors including alcoholism and drug abuse are not uncommon for those who participate in the euthanasia of animals.

Euthanasia of Cattle: Practical Considerations and Application

Directory of Open Access Journals (Sweden)

Jan Keith Shearer

2018-04-01

Full Text Available Acceptable methods for the euthanasia of cattle include overdose of an anesthetic, gunshot and captive bolt. The use of anesthetics for euthanasia is costly and complicates carcass disposal. These issues can be avoided by use of a physical method such as gunshot or captive bolt; however, each requires that certain conditions be met to assure an immediate loss of consciousness and death. For example, the caliber of firearm and type of bullet are important considerations when gunshot is used. When captive bolt is used, a penetrating captive bolt loaded with the appropriate powder charge and accompanied by a follow up (adjunctive step to assure death are required. The success of physical methods also requires careful selection of the anatomic site for entry of a “free bullet” or “bolt” in the case of penetrating captive bolt. Disease eradication plans for animal health emergencies necessitate methods of euthanasia that will facilitate rapid and efficient depopulation of animals while preserving their welfare to the greatest extent possible. A portable pneumatic captive bolt device has been developed and validated as effective for use in mass depopulation scenarios. Finally, while most tend to focus on the technical aspects of euthanasia, it is extremely important that no one forget the human cost for those who may be required to perform the task of euthanasia on a regular basis. Symptoms including depression, grief, sleeplessness and destructive behaviors including alcoholism and drug abuse are not uncommon for those who participate in the euthanasia of animals.

Brookhaven National Laboratory source water assessment for drinking water supply wells

International Nuclear Information System (INIS)

Bennett, D.B.; Paquette, D.E.; Klaus, K.; Dorsch, W.R.

2000-01-01

The BNL water supply system meets all water quality standards and has sufficient pumping and storage capacity to meet current and anticipated future operational demands. Because BNL's water supply is drawn from the shallow Upper Glacial aquifer, BNL's source water is susceptible to contamination. The quality of the water supply is being protected through (1) a comprehensive program of engineered and operational controls of existing aquifer contamination and potential sources of new contamination, (2) groundwater monitoring, and (3) potable water treatment. The BNL Source Water Assessment found that the source water for BNL's Western Well Field (comprised of Supply Wells 4, 6, and 7) has relatively few threats of contamination and identified potential sources are already being carefully managed. The source water for BNL's Eastern Well Field (comprised of Supply Wells 10, 11, and 12) has a moderate number of threats to water quality, primarily from several existing volatile organic compound and tritium plumes. The g-2 Tritium Plume and portions of the Operable Unit III VOC plume fall within the delineated source water area for the Eastern Well Field. In addition, portions of the much slower migrating strontium-90 plumes associated with the Brookhaven Graphite Research Reactor, Waste Concentration Facility and Building 650 lie within the Eastern source water area. However, the rate of travel in the aquifer for strontium-90 is about one-twentieth of that for tritium and volatile organic compounds. The Laboratory has been carefully monitoring plume migration, and has made adjustments to water supply operations. Although a number of BNL's water supply wells were impacted by VOC contamination in the late 1980s, recent routine analysis of water samples from BNL's supply wells indicate that no drinking water standards have been reached or exceeded. The high quality of the water supply strongly indicates that the operational and engineered controls implemented over the past

Manufacture of Third-Generation Lentivirus for Preclinical Use, with Process Development Considerations for Translation to Good Manufacturing Practice.

Science.gov (United States)

Gándara, Carolina; Affleck, Valerie; Stoll, Elizabeth Ann

2018-02-01

Lentiviral vectors are used in laboratories around the world for in vivo and ex vivo delivery of gene therapies, and increasingly clinical investigation as well as preclinical applications. The third-generation lentiviral vector system has many advantages, including high packaging capacity, stable gene expression in both dividing and post-mitotic cells, and low immunogenicity in the recipient organism. Yet, the manufacture of these vectors is challenging, especially at high titers required for direct use in vivo, and further challenges are presented by the process of translating preclinical gene therapies toward manufacture of products for clinical investigation. The goals of this paper are to report the protocol for manufacturing high-titer third-generation lentivirus for preclinical testing and to provide detailed information on considerations for translating preclinical viral vector manufacture toward scaled-up platforms and processes in order to make gene therapies under Good Manufacturing Practice that are suitable for clinical trials.

Introduction of organic/hydro-organic matrices in inductively coupled plasma optical emission spectrometry and mass spectrometry: A tutorial review. Part II. Practical considerations

Energy Technology Data Exchange (ETDEWEB)

Leclercq, Amélie, E-mail: amelie.leclercq@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Nonell, Anthony, E-mail: anthony.nonell@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Todolí Torró, José Luis, E-mail: jose.todoli@ua.es [Universidad de Alicante, Departamento de Quimica Analitica, Nutricion y Bromatología, Ap. de Correos, 99, 03080 Alicante (Spain); Bresson, Carole, E-mail: carole.bresson@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Vio, Laurent, E-mail: laurent.vio@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Vercouter, Thomas, E-mail: thomas.vercouter@cea.fr [CEA Saclay, DEN, DANS, DPC, SEARS, Laboratoire de développement Analytique Nucléaire Isotopique et Elémentaire, 91191 Gif-sur-Yvette (France); Chartier, Frédéric, E-mail: frederic.chartier@cea.fr [CEA Saclay, DEN, DANS, DPC, 91191 Gif-sur-Yvette (France)

2015-07-23

Graphical abstract: This tutorial review is dedicated to the analysis of organic/hydro-organic matrices by ICP techniques. A state-of-the-art focusing on sample introduction, relevant operating parameters optimization and analytical strategies for elemental quantification is provided. - Highlights: • Practical considerations to perform analyses in organic/hydro-organic matrices. • Description, benefits and drawbacks of recent introduction devices. • Optimization to improve plasma tolerance towards organic/hydro-organic matrices. • Analytical strategies for elemental quantification in organic/hydro-organic matrices. - Abstract: Inductively coupled plasma optical emission spectrometry (ICP-OES) and mass spectrometry (ICP-MS) are increasingly used to carry out analyses in organic/hydro-organic matrices. The introduction of such matrices into ICP sources is particularly challenging and can be the cause of numerous drawbacks. This tutorial review, divided in two parts, explores the rich literature related to the introduction of organic/hydro-organic matrices in ICP sources. Part I provided theoretical considerations associated with the physico-chemical properties of such matrices, in an attempt to understand the induced phenomena. Part II of this tutorial review is dedicated to more practical considerations on instrumentation, instrumental and operating parameters, as well as analytical strategies for elemental quantification in such matrices. Two important issues are addressed in this part: the first concerns the instrumentation and optimization of instrumental and operating parameters, pointing out (i) the description, benefits and drawbacks of different kinds of nebulization and desolvation devices and the impact of more specific instrumental parameters such as the injector characteristics and the material used for the cone; and, (ii) the optimization of operating parameters, for both ICP-OES and ICP-MS. Even if it is at the margin of this tutorial review

Introduction of organic/hydro-organic matrices in inductively coupled plasma optical emission spectrometry and mass spectrometry: A tutorial review. Part II. Practical considerations

International Nuclear Information System (INIS)

Leclercq, Amélie; Nonell, Anthony; Todolí Torró, José Luis; Bresson, Carole; Vio, Laurent; Vercouter, Thomas; Chartier, Frédéric

2015-01-01

Graphical abstract: This tutorial review is dedicated to the analysis of organic/hydro-organic matrices by ICP techniques. A state-of-the-art focusing on sample introduction, relevant operating parameters optimization and analytical strategies for elemental quantification is provided. - Highlights: • Practical considerations to perform analyses in organic/hydro-organic matrices. • Description, benefits and drawbacks of recent introduction devices. • Optimization to improve plasma tolerance towards organic/hydro-organic matrices. • Analytical strategies for elemental quantification in organic/hydro-organic matrices. - Abstract: Inductively coupled plasma optical emission spectrometry (ICP-OES) and mass spectrometry (ICP-MS) are increasingly used to carry out analyses in organic/hydro-organic matrices. The introduction of such matrices into ICP sources is particularly challenging and can be the cause of numerous drawbacks. This tutorial review, divided in two parts, explores the rich literature related to the introduction of organic/hydro-organic matrices in ICP sources. Part I provided theoretical considerations associated with the physico-chemical properties of such matrices, in an attempt to understand the induced phenomena. Part II of this tutorial review is dedicated to more practical considerations on instrumentation, instrumental and operating parameters, as well as analytical strategies for elemental quantification in such matrices. Two important issues are addressed in this part: the first concerns the instrumentation and optimization of instrumental and operating parameters, pointing out (i) the description, benefits and drawbacks of different kinds of nebulization and desolvation devices and the impact of more specific instrumental parameters such as the injector characteristics and the material used for the cone; and, (ii) the optimization of operating parameters, for both ICP-OES and ICP-MS. Even if it is at the margin of this tutorial review

Practical considerations and patient selection for intrathecal drug delivery in the management of chronic pain

Directory of Open Access Journals (Sweden)

Saulino M

2014-11-01

assessed in three double-blind, placebo-controlled trials of 457 patients, and safety has been assessed in 1,254 patients overall, with severe chronic cancer, noncancer, and acquired immunodeficiency syndrome pain types. Both agents are highlighted as first-line intrathecal therapy for the management of neuropathic or nociceptive pain. The purpose of this review is to discuss practical considerations for intrathecal drug delivery, delineate criteria for the identification and selection of candidates for intrathecal drug delivery, and consider which agent may be more appropriate for individual patients. Keywords: review, patient selection, chronic pain, intrathecal, drug delivery

Local Anesthetics: Review of Pharmacological Considerations

Science.gov (United States)

Becker, Daniel E; Reed, Kenneth L

2012-01-01

Local anesthetics have an impressive history of efficacy and safety in medical and dental practice. Their use is so routine, and adverse effects are so infrequent, that providers may understandably overlook many of their pharmacotherapeutic principles. The purpose of this continuing education article is to provide a review and update of essential pharmacology for the various local anesthetic formulations in current use. Technical considerations will be addressed in a subsequent article. PMID:22822998

Civic ecology practices: insights from practice theory

Directory of Open Access Journals (Sweden)

Marianne E. Krasny

2015-06-01

Full Text Available Our aim was to explore the use of practice theory as an approach to studying urban environmental stewardship. Urban environmental stewardship, or civic ecology practice, contributes to ecosystem services and community well-being and has been studied using social-ecological systems resilience, property rights, communities of practice, and governance frameworks. Practice theory, which previously has been applied in studies of consumer behaviors, adds a new perspective to urban stewardship research, focusing on how elements of a practice, such as competencies, meanings, and physical resource, together define the practice. We applied practice theory to eight different civic ecology practices, including oyster gardening in New York City, a civil society group engaged in litter cleanup in Iran, and village grove restoration in South Korea. Our analysis suggests that in applying practice theory to the civic ecology context, consideration should be given to social and communication competencies, how meanings can motivate volunteers and sustain practice, and the nature of the resource that is being stewarded. Future studies may want to focus on how practice elements interact within and vary across practices and may be used to more systematically analyze and share ideas among diverse civic ecology practices.

Evaluating programs that address ideological issues: ethical and practical considerations for practitioners and evaluators.

Science.gov (United States)

Lieberman, Lisa D; Fagen, Michael C; Neiger, Brad L

2014-03-01

There are important practical and ethical considerations for organizations in conducting their own, or commissioning external, evaluations and for both practitioners and evaluators, when assessing programs built on strongly held ideological or philosophical approaches. Assessing whether programs "work" has strong political, financial, and/or moral implications, particularly when expending public dollars, and may challenge objectivity about a particular program or approach. Using a case study of the evaluation of a school-based abstinence-until-marriage program, this article discusses the challenges, lessons learned, and ethical responsibilities regarding decisions about evaluation, specifically associated with ideologically driven programs. Organizations should consider various stakeholders and views associated with their program to help identify potential pitfalls in evaluation. Once identified, the program or agency needs to carefully consider its answers to two key questions: Do they want the answer and are they willing to modify the program? Having decided to evaluate, the choice of evaluator is critical to assuring that ethical principles are maintained and potential skepticism or criticism of findings can be addressed appropriately. The relationship between program and evaluator, including agreements about ownership and eventual publication and/or promotion of data, should be addressed at the outset. Programs and organizations should consider, at the outset, their ethical responsibility when findings are not expected or desired. Ultimately, agencies, organizations, and programs have an ethical responsibility to use their data to provide health promotion programs, whether ideologically founded or not, that appropriately and effectively address the problems they seek to solve.

Some practical considerations in finite element-based digital image correlation

KAUST Repository

Wang, Bo; Pan, Bing; Lubineau, Gilles

2015-01-01

effectively tackle these issues. First, to better accommodate the possible intensity variations of the deformed images practically occurred in real experiments, a robust zero-mean normalized sum of squared difference criterion, instead of the commonly used sum

Regulatory good practices relating to inspection and enforcement. A compilation of the 1989/90 Peer Group discussion considerations as they relate to operational plants. Working material

International Nuclear Information System (INIS)

1993-01-01

In 1974 the IAEA established a special Nuclear Safety Standards (NUSS) programme under which 5 Codes and 55 Safety Guides have been produced in the areas of Governmental Organization, Siting, Design, Operation and Quality Assurance. The NUSS Codes and Guides are a collection of basic and derived requirements for the safety of nuclear power plants with thermal neutron reactors. They have been developed in a complex manner which ensured the best possible international consensus. This broad consensus is one of the reasons for a relatively general wording of the main principles and is sometimes a cause of problems in their application to the detailed design of nuclear power plants. The requirements, particularly those of the Codes, often need interpretation when applied to specific cases. In many areas national regulations and technical standards are available, but often even these do not answer all questions and only the practice used in applying certain rules fully reflects the outcome of the detailed consideration given to solving individual cases. In order to present further information on the application and interpretation in the NUSS Codes and Safety Guides, the preparation of a series of Safety Practice publications has been initiated. It is hoped that many Member States will be able to benefit from the experience presented in these documents. It is hoped that this publication will be useful for regulators and will also provide information for operating organizations. The document is a compilation of the reports of all of the 1989/90 Peer Group discussions held to consider regulatory inspection and enforcement of good practices. Therefore names of participated countries or the situation of regulatory practices reflect those at time when discussions took place. It identifies those common regulatory features which require continuous reinforcement and the examples of good regulatory practices which were recommended by the senior regulators attending the Peer Group

Regulatory good practices relating to inspection and enforcement. A compilation of the 1989/90 Peer Group discussion considerations as they relate to operational plants. Working material

Energy Technology Data Exchange (ETDEWEB)

NONE

1993-07-01

In 1974 the IAEA established a special Nuclear Safety Standards (NUSS) programme under which 5 Codes and 55 Safety Guides have been produced in the areas of Governmental Organization, Siting, Design, Operation and Quality Assurance. The NUSS Codes and Guides are a collection of basic and derived requirements for the safety of nuclear power plants with thermal neutron reactors. They have been developed in a complex manner which ensured the best possible international consensus. This broad consensus is one of the reasons for a relatively general wording of the main principles and is sometimes a cause of problems in their application to the detailed design of nuclear power plants. The requirements, particularly those of the Codes, often need interpretation when applied to specific cases. In many areas national regulations and technical standards are available, but often even these do not answer all questions and only the practice used in applying certain rules fully reflects the outcome of the detailed consideration given to solving individual cases. In order to present further information on the application and interpretation in the NUSS Codes and Safety Guides, the preparation of a series of Safety Practice publications has been initiated. It is hoped that many Member States will be able to benefit from the experience presented in these documents. It is hoped that this publication will be useful for regulators and will also provide information for operating organizations. The document is a compilation of the reports of all of the 1989/90 Peer Group discussions held to consider regulatory inspection and enforcement of good practices. Therefore names of participated countries or the situation of regulatory practices reflect those at time when discussions took place. It identifies those common regulatory features which require continuous reinforcement and the examples of good regulatory practices which were recommended by the senior regulators attending the Peer Group

Transition to Office-based Obstetric and Gynecologic Procedures: Safety, Technical, and Financial Considerations.

Science.gov (United States)

Peacock, Lisa M; Thomassee, May E; Williams, Valerie L; Young, Amy E

2015-06-01

Office-based surgery is increasingly desired by patients and providers due to ease of access, overall efficiency, reimbursement, and satisfaction. The adoption of office-based surgery requires careful consideration of safety, efficacy, cost, and feasibility within a providers practice. This article reviews the currently available data regarding patient and provider satisfaction as well as practical considerations of staffing, equipment, and supplies. To aid the practitioner, issues of office-based anesthesia and safety with references to currently available national guidelines and protocols are provided. Included is a brief review of billing, coding, and reimbursement. Technical procedural aspects with information and recommendations are summarized.

PREVENTING POLLUTION USING ISO 14001 AT A PARTICLE ACCELERATOR THE RELATIVISTIC HEAVY ION COLLIDER PROJECT

International Nuclear Information System (INIS)

BRIGGS, S.L.K.; MUSOLINO, S.V.

2001-01-01

In early 1997 Brookhaven National Laboratory (BNL) discovered that the spent fuel pool of their High Flux Beam Reactor was leaking tritium into the groundwater. Community members, activist groups, politicians and regulators were outraged with the poor environmental management practices at BNL. The reactor was shut down and the Department of Energy (DOE) terminated the contract with the existing Management Company. At this same time, a major new scientific facility, the Relativistic Heavy Ion Collider (RHIC), was nearing the end of construction and readying for commissioning. Although environmental considerations had been incorporated into the design of the facility; some interested parties were skeptical that this new facility would not cause significant environmental impacts. RHIC management recognized that the future of its operation was dependent on preventing pollution and allaying concerns of its stakeholders. Although never done at a DOE National Laboratory before Brookhaven Science Associates, the new management firm, committed to implementing an Environmental Management System (EMS) and RHIC managers volunteered to deploy it within their facility on an extremely aggressive schedule. Several of these IS0 requirements contribute directly to preventing pollution, an area where particular emphasis was placed. This paper describes how Brookhaven used the following key IS0 14001 elements to institutionalize Pollution Prevention concepts: Environmental Policy, Aspects, Objectives and Targets, Environmental Management Program, Structure and Responsibility, Operational Controls, Training, and Management Review. In addition, examples of implementation at the RHIC Project illustrate how BNL's premiere facility was able to demonstrate to interested parties that care had been taken to implement technological and administrative controls to minimize environmental impacts, while at the same time reduce the applicability of regulatory requirements to their operations

Practical Considerations in Creating School-Wide Positive Behavior Support in Public Schools

Science.gov (United States)

Handler, Marcie W.; Rey, Jannette; Connell, James; Thier, Kimberly; Feinberg, Adam; Putnam, Robert

2007-01-01

School-wide positive behavior support (SWPBS) has been identified as an effective and efficient method to teach students prosocial skills. It requires both effective behavior support practices and systems that will support these changes, including data-based decision making among the school leadership team. There are many practical and systemic…

Headaches of otolaryngological interest: current status while awaiting revision of classification. Practical considerations and expectations.

Science.gov (United States)

Farri, A; Enrico, A; Farri, F

2012-04-01

In 1988, diagnostic criteria for headaches were drawn up by the International Headache Society (IHS) and is divided into headaches, cranial neuralgias and facial pain. The 2(nd) edition of the International Classification of Headache Disorders (ICHD) was produced in 2004, and still provides a dynamic and useful instrument for clinical practice. We have examined the current IHC, which comprises 14 groups. The first four cover primary headaches, with "benign paroxysmal vertigo of childhood" being the forms of migraine of interest to otolaryngologists; groups 5 to 12 classify "secondary headaches"; group 11 is formed of "headache or facial pain attributed to disorder of cranium, neck, eyes, ears, nose, sinuses, teeth, mouth or other facial or cranial structures"; group 13, consisting of "cranial neuralgias and central causes of facial pain" is also of relevance to otolaryngology. Neither the current classification system nor the original one has a satisfactory collocation for migraineassociated vertigo. Another critical point of the classification concerns cranio-facial pain syndromes such as Sluder's neuralgia, previously included in the 1988 classification among cluster headaches, and now included in the section on "cranial neuralgias and central causes of facial pain", even though Sluder's neuralgia has not been adequately validated. As we have highlighted in our studies, there are considerable similarities between Sluder's syndrome and cluster headaches. The main features distinguishing the two are the trend to cluster over time, found only in cluster headaches, and the distribution of pain, with greater nasal manifestations in the case of Sluder's syndrome. We believe that it is better and clearer, particularly on the basis of our clinical experience and published studies, to include this nosological entity, which is clearly distinct from an otolaryngological point of view, as a variant of cluster headache. We agree with experts in the field of headaches, such as

Starting a business as a nurse consultant: practical considerations.

Science.gov (United States)

Papp, E M

2000-03-01

Nursing experience translates well to self employment in the occupational and environmental health field. However, nurses must conduct a self assessment to determine whether owning a business is a good fit for their personality and work style. Exploring which services to offer is the next step in starting a business and consists of determining not only which service to offer (e.g., writing policies or protocols, providing clinical services) but also which type of consultation model to use (i.e., purchase of expertise, doctor/client, process consultation). Every business must have a plan. A business plan is essential to starting a business. It solidifies the entrepreneur's focus, lays the foundation for the business, provides a tool for evaluating success, and is a strong tool for soliciting financial support. The name of the business is an important consideration because it is often the first contact the customers have with the occupational health nurse consultant. The name must be descriptive, appropriate, and memorable.

Effect of the solenoid in various conditions of the laser ion source at Brookhaven National Laboratory

Science.gov (United States)

Ikeda, S.; Kumaki, M.; Kanesue, T.; Okamura, M.

2016-02-01

In the laser ion source (LIS) at the Brookhaven National Laboratory (BNL), a solenoid is used to guide the laser ablation plasma and modulate the extracted beam current. Many types of ion species are guided. In some cases, the plasma plume is injected into the solenoid away from the solenoidal axis. To investigate the effects of the solenoid on the beam extracted from the plasma that has different properties, the beam current was measured in the setup of the LIS at the BNL. The beam current of Li, Al, Si, Fe, and Au increased when the magnetic field was applied. For most of the species the peak current and the total charge within a single beam pulse increased around 10 times with a magnetic field less than 100 G. In addition, for some species the rate of increase of the peak currents became smaller when the magnetic flux densities were larger than certain values depending on the species. In this case, the current waveforms were distorted. At the same magnetic field value, the field was more effective on lighter species than on heavier ones. When plasma was injected offset from the axis of the solenoid, peak current and total charge became half of those without offset. The experimental data are useful for the operation of the LIS at the BNL.

Effect of the solenoid in various conditions of the laser ion source at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Ikeda, S.; Kumaki, M.; Kanesue, T.; Okamura, M.

2016-01-01

In the laser ion source (LIS) at the Brookhaven National Laboratory (BNL), a solenoid is used to guide the laser ablation plasma and modulate the extracted beam current. Many types of ion species are guided. In some cases, the plasma plume is injected into the solenoid away from the solenoidal axis. To investigate the effects of the solenoid on the beam extracted from the plasma that has different properties, the beam current was measured in the setup of the LIS at the BNL. The beam current of Li, Al, Si, Fe, and Au increased when the magnetic field was applied. For most of the species the peak current and the total charge within a single beam pulse increased around 10 times with a magnetic field less than 100 G. In addition, for some species the rate of increase of the peak currents became smaller when the magnetic flux densities were larger than certain values depending on the species. In this case, the current waveforms were distorted. At the same magnetic field value, the field was more effective on lighter species than on heavier ones. When plasma was injected offset from the axis of the solenoid, peak current and total charge became half of those without offset. The experimental data are useful for the operation of the LIS at the BNL

Effect of the solenoid in various conditions of the laser ion source at Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Ikeda, S., E-mail: ikeda.s.ae@m.titech.ac.jp [Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, Yokohama, Kanagawa 216-8502 (Japan); Nishina Center for Accelerator-Based Science, RIKEN, Wako, Saitama 351-0108 (Japan); Kumaki, M. [Nishina Center for Accelerator-Based Science, RIKEN, Wako, Saitama 351-0108 (Japan); Kanesue, T.; Okamura, M. [Collider-Accelerator Department, Brookhaven National Laboratory, Upton, New York 11973-5000 (United States)

2016-02-15

In the laser ion source (LIS) at the Brookhaven National Laboratory (BNL), a solenoid is used to guide the laser ablation plasma and modulate the extracted beam current. Many types of ion species are guided. In some cases, the plasma plume is injected into the solenoid away from the solenoidal axis. To investigate the effects of the solenoid on the beam extracted from the plasma that has different properties, the beam current was measured in the setup of the LIS at the BNL. The beam current of Li, Al, Si, Fe, and Au increased when the magnetic field was applied. For most of the species the peak current and the total charge within a single beam pulse increased around 10 times with a magnetic field less than 100 G. In addition, for some species the rate of increase of the peak currents became smaller when the magnetic flux densities were larger than certain values depending on the species. In this case, the current waveforms were distorted. At the same magnetic field value, the field was more effective on lighter species than on heavier ones. When plasma was injected offset from the axis of the solenoid, peak current and total charge became half of those without offset. The experimental data are useful for the operation of the LIS at the BNL.

Practical consideration of nuclear fuel spiking for proliferation deterrence

International Nuclear Information System (INIS)

Selle, J.E.; Angelini, P.; Rainey, R.H.; Federer, J.I.; Olsen, A.R.

1978-10-01

The use of a gamma active radionuclide with nuclear fuel has been proposed as a way to inhibit unauthorized diversion of the fuel and thus provide proliferation deterrence. The purpose of this report is to examine some of the practical aspects of incorporating spikants into nuclear fuel in an attempt to identify any adverse consequences of their use. Selection of potential spikants was made by the application of some somewhat arbitrary radiation criteria to 64 candidate spikants followed by an analysis of the chemical and physical state of each potential spikant. As a result of this analysis the list of candidates was narrowed to 60 Co, 106 Ru, and 144 Ce. Following this, we investigated the practical aspects of the use of these three spikants in nuclear fuel. Among the subjects considered are: dose rates available from fuel elements, fission product buildup, chemical behavior of spikants during reproecssing, and possible effects of spikants on refabrication and on the fuel properties. No single radionuclide was found to be preferred in all stages of reprocessing and refabriaction. In order to provide deterrence in all stages of reprocessing and refabrication, a duplex spiking process appears necessary, in which two different spikants, 106 Ru and 60 Co, are used in different portions of reprocessing. The use of nominal amounts of ruthenium or cobalt as spikants is not expected to adversely affect fuel performance

Play therapy: considerations and applications for the practitioner.

Science.gov (United States)

Kool, Ritesh; Lawver, Timothy

2010-10-01

Play therapy represents a unique form of treatment that is not only geared toward young children, but is translated into a language children can comprehend and utilize-the language of play. For the referring provider or practitioner, questions may remain regarding the nature, course, and efficacy of play therapy. This article reviews the theoretical underpinnings of play therapy, some practical considerations, and finally a summary of the current state of research in regard to play therapy. The authors present the practicing psychiatrist with a road map for referring a patient to play therapy or initiating it in appropriate cases.

How strategic considerations influence decision making on e-HRM applications

NARCIS (Netherlands)

Schalk, R.; Timmerman, V.; van den Heuvel, S.R.H.

2013-01-01

Although numerous studies indicate that the added value of human resource management is strongest when HRM decisions are linked to the organizational strategy, practical knowledge about how strategic considerations influence decision-making processes relating to e-HRM is limited. Therefore, the

Practical Considerations Concerning the Interleaved Transition Mode Single-stage Ballast

DEFF Research Database (Denmark)

Teodorescu, Remus; Kjær, Søren Bækhøj; Munk-Nielsen, Stig

2002-01-01

The aim of this paper is to present a novel single-stage interleaved ballast focusing on practical design aspects like: key current expression, overall losses, harmonic analysis of the differential-mode EMI current and preheating ballast function. A new preheating method is also presented. A PSPICE...

Disclosure of information and informed consent: ethical and practical considerations.

Science.gov (United States)

Steinberg, Avraham

2009-12-01

Disclosure of information and informed consent are relatively new concepts in the patient-physician relationship. They are based primarily on the principle of autonomy and they have many favorable practical advantages. However, the practical implementation of these requirements is fraught with difficulties, some of which can cause harm to the patient or be obstacles in fulfilling the moral obligation of beneficence. This is particularly true when disclosure of information and informed consent are done by physicians in a defensive way for fear of malpractice suits. The most ethically defensible approach is to tailor and navigate the information according to the needs and desires of each individual patient in a sensitive and empathic manner. The informed consent should be a process of mutually shared responsibility by the patient and the physician, ensuring adequate and relevant information that is well comprehended by the individual patient, and is used correctly for his or her decision making.

Paediatricians, social media and blogs: Ethical considerations

OpenAIRE

St-Laurent-Gagnon, Thérèse; Coughlin, Kevin W

2012-01-01

The use of blogs, Facebook and similar social networking sites is rapidly expanding and, when compared with e-mail, may be having a significantly different impact on the traditional doctor-patient relationship. Characteristics specific to these online platforms have major implications for professional relationships, including the ‘Facebook effect’ (the relative permanence of postings) and the ‘online disinhibition effect’. The present practice point illustrates relevant ethical considerations...

Assessment: Examining Practice in Entrepreneurship Education

Science.gov (United States)

Pittaway, Luke; Edwards, Corina

2012-01-01

Purpose: The purpose of this paper is to develop knowledge about the nature of student assessment practice in entrepreneurship education. Design/methodology/approach: This paper introduces general assessment practice issues and highlights key considerations. It explains prior research on assessment practice in entrepreneurship education and argues…

Ethical considerations for field research on fishes

Directory of Open Access Journals (Sweden)

Rhett H. Bennett

2016-12-01

Full Text Available Collection of data from animals for research purposes can negatively impact target or by-catch species if suitable animal ethics practices are not followed. This study aimed to assess the ethical requirements of peer-reviewed scientific journals that publish primary literature on fishes, and review the ethical considerations and animal care guidelines of national and international documents on the ethical treatment of animals for research, to provide an overview of the general ethical considerations for field research on fishes. A review of 250 peer-reviewed, ISI-rated journals publishing primary research on fishes revealed that nearly half (46% had no mention of ethics, treatment of animals or ethical requirements for publication in their author guidelines or publication policies. However, 18% of the journals reviewed identify a specific set of ethical guidelines to be followed before publishing research involving animals. Ethical considerations for investigators undertaking field research on fishes, common to most animal care policies, legislation and guiding documents, include adhering to relevant legislation, minimising sample sizes, reducing or mitigating pain and distress, employing the most appropriate and least invasive techniques and accurately reporting methods and findings. This information will provide potential investigators with a useful starting point for designing and conducting ethical field research. Application of ethical best practices in field sampling studies will improve the welfare of study animals and the conservation of rare and endangered species. Conservation implications: This article provides a list of ethical considerations for designing and conducting field research on fishes. By reviewing sampling techniques and processes that are frequently used in field research on fishes and by highlighting the potential negative impacts of these sampling techniques, this article is intended to assist researchers in planning

Particulate Matter Filtration Design Considerations for Crewed Spacecraft Life Support Systems

Science.gov (United States)

Agui, Juan H.; Vijayakumar, R.; Perry, Jay L.

2016-01-01

Particulate matter filtration is a key component of crewed spacecraft cabin ventilation and life support system (LSS) architectures. The basic particulate matter filtration functional requirements as they relate to an exploration vehicle LSS architecture are presented. Particulate matter filtration concepts are reviewed and design considerations are discussed. A concept for a particulate matter filtration architecture suitable for exploration missions is presented. The conceptual architecture considers the results from developmental work and incorporates best practice design considerations.

Acceleration of cardiovascular MRI using parallel imaging: basic principles, practical considerations, clinical applications and future directions

International Nuclear Information System (INIS)

Niendorf, T.; Sodickson, D.

2006-01-01

Cardiovascular Magnetic Resonance (CVMR) imaging has proven to be of clinical value for non-invasive diagnostic imaging of cardiovascular diseases. CVMR requires rapid imaging; however, the speed of conventional MRI is fundamentally limited due to its sequential approach to image acquisition, in which data points are collected one after the other in the presence of sequentially-applied magnetic field gradients and radiofrequency coils to acquire multiple data points simultaneously, and thereby to increase imaging speed and efficiency beyond the limits of purely gradient-based approaches. The resulting improvements in imaging speed can be used in various ways, including shortening long examinations, improving spatial resolution and anatomic coverage, improving temporal resolution, enhancing image quality, overcoming physiological constraints, detecting and correcting for physiologic motion, and streamlining work flow. Examples of these strategies will be provided in this review, after some of the fundamentals of parallel imaging methods now in use for cardiovascular MRI are outlined. The emphasis will rest upon basic principles and clinical state-of-the art cardiovascular MRI applications. In addition, practical aspects such as signal-to-noise ratio considerations, tailored parallel imaging protocols and potential artifacts will be discussed, and current trends and future directions will be explored. (orig.)

Bioanalytical method transfer considerations of chromatographic-based assays.

Science.gov (United States)

Williard, Clark V

2016-07-01

Bioanalysis is an important part of the modern drug development process. The business practice of outsourcing and transferring bioanalytical methods from laboratory to laboratory has increasingly become a crucial strategy for successful and efficient delivery of therapies to the market. This chapter discusses important considerations when transferring various types of chromatographic-based assays in today's pharmaceutical research and development environment.

Safe practices and financial considerations in using oral chemotherapeutic agents.

Science.gov (United States)

Bartel, Sylvia B

2007-05-01

Safe handling practices and financial concerns associated with oral chemotherapy in non-traditional settings are discussed. Oral chemotherapy may pose a risk to patients because of a narrow therapeutic index, complex dosing regimen, dispensing by community pharmacists without prescription order review by an oncology pharmacist or nurse, or self-administration in the home or another nontraditional setting, where patient monitoring is infrequent. Errors in prescribing, dispensing, and administration and patient or caregiver misunderstandings are potential problems with the use of oral chemotherapy that need to be addressed when developing safe practices. Changes in Medicare pharmaceutical reimbursement rates and rules need to be monitored because they have the potential to affect patient care and outcomes. Patient assistance programs and advocacy groups can help alleviate financial concerns associated with oral chemotherapy. Consensus guidelines specific to safe handling of oral chemotherapy in the home or other nontraditional setting need to be developed. Also, healthcare providers must understand reimbursement and provide direction to patients when patient assistance programs or advocacy groups can assist with the financial challenges of oral chemotherapy.

Justification and radiology: some ethical considerations.

Science.gov (United States)

Sia, Santiago

2009-07-01

This paper, which seeks to address the issue of justification in radiology, intends firstly to comment on the current discussion of the ethical foundation of radiological practice that focuses on the move from utilitarianism to the rights-centred criterion. Secondly, and this constitutes the bulk of the paper, it aims to offer a philosophical perspective, which is hoped will lead to a consideration of certain specific areas in ethical decision-making in the attempts here to deal with the main issue of justification in radiology.

Justification and radiology: Some ethical considerations

International Nuclear Information System (INIS)

Sia, S.

2009-01-01

This paper, which seeks to address the issue of justification in radiology, intends firstly to comment on the current discussion of the ethical foundation of radiological practice that focuses on the move from utilitarianism to the rights-centred criterion. Secondly, and this constitutes the bulk of the paper, it aims to offer a philosophical perspective, which is hoped will lead to a consideration of certain specific areas in ethical decision-making in the attempts here to deal with the main issue of justification in radiology. (authors)

Clinical social work practice and technology: personal, practical, regulatory, and ethical considerations for the twenty-first century.

Science.gov (United States)

Dombo, Eileen A; Kays, Lisa; Weller, Katelyn

2014-10-01

The world that social work exists in is no longer defined by traditional physical settings and boundaries, such as schools, agencies, or even offices. With the advent of the Internet and digital communications, social work now exists in a far more complex reality, with clients and social workers engaging across multiple platforms, and sometimes even unintentionally and without one another's awareness. The implications of this can be ethical, practical, regulatory, and personal. This article explores these areas of concern and suggests strategies professionals can use to navigate these complex issues related to technology and clinical practice.

Modelling Practice

DEFF Research Database (Denmark)

Cameron, Ian; Gani, Rafiqul

2011-01-01

This chapter deals with the practicalities of building, testing, deploying and maintaining models. It gives specific advice for each phase of the modelling cycle. To do this, a modelling framework is introduced which covers: problem and model definition; model conceptualization; model data...... requirements; model construction; model solution; model verification; model validation and finally model deployment and maintenance. Within the adopted methodology, each step is discussedthrough the consideration of key issues and questions relevant to the modelling activity. Practical advice, based on many...

General practitioners' management of mental disorders: A rewarding practice with considerable obstacles

Directory of Open Access Journals (Sweden)

Fleury Marie-Josée

2012-03-01

Full Text Available Abstract Background Primary care improvement is the cornerstone of current reforms. Mental disorders (MDs are a leading cause of morbidity worldwide and widespread in industrialised countries. MDs are treated mainly in primary care by general practitioners (GPs, even though the latter ability to detect, diagnose, and treat patients with MDs is often considered unsatisfactory. This article examines GPs' management of MDs in an effort to acquire more information regarding means by which GPs deal with MD cases, impact of such cases on their practices, factors that enable or hinder MD management, and patient-management strategies. Methods This study employs a mixed-method approach with emphasis on qualitative investigation. Based on a previous survey of 398 GPs in Quebec, Canada, 60 GPs representing a variety of practice settings were selected for further study. A 10-minute-long questionnaire comprising 27 items was administered, and 70-minute-long interviews were conducted. Quantitative (SPSS and qualitative (NVivo analyses were performed. Results At least 20% of GP visits were MD-related. GPs were comfortable managing common MDs, but not serious MDs. GPs' based their treatment of MDs on pharmacotherapy, support therapy, and psycho-education. They used clinical intuition with few clinical tools, and closely followed their patients with MDs. Practice features (salary or hourly fees payment; psycho-social teams on-site; strong informal networks, and GPs' individual characteristics (continuing medical education; exposure and interest in MDs; traits like empathy favoured MD management. Collaboration with psychologists and psychiatrists was considered key to good MD management. Limited access to specialists, system fragmentation, and underdeveloped group practice and shared-care models were impediments. MD management was seen as burdensome because it required more time, flexibility, and emotional investment. Strategies exist to reduce the burden (one

Construction and operation of an improved radiation calibration facility at Brookhaven National Laboratory. Environmental assessment

International Nuclear Information System (INIS)

1994-10-01

Calibration of instruments used to detect and measure ionizing radiation has been conducted over the last 20 years at Brookhaven National Laboratory's (BNL) Radiation Calibration Facility, Building 348. Growth of research facilities, projects in progress, and more stringent Department of Energy (DOE) orders which involve exposure to nuclear radiation have placed substantial burdens on the existing radiation calibration facility. The facility currently does not meet the requirements of DOE Order 5480.4 or American National Standards Institute (ANSI) N323-1978, which establish calibration methods for portable radiation protection instruments used in the detection and measurement of levels of ionizing radiation fields or levels of radioactive surface contaminations. Failure to comply with this standard could mean instrumentation is not being calibrated to necessary levels of sensitivity. The Laboratory has also recently obtained a new neutron source and gamma beam irradiator which can not be made operational at existing facilities because of geometry and shielding inadequacies. These sources are needed to perform routine periodic calibrations of radiation detecting instruments used by scientific and technical personnel and to meet BNL's substantial increase in demand for radiation monitoring capabilities. To place these new sources into operation, it is proposed to construct an addition to the existing radiation calibration facility that would house all calibration sources and bring BNL calibration activities into compliance with DOE and ANSI standards. The purpose of this assessment is to identify potential significant environmental impacts associated with the construction and operation of an improved radiation calibration facility at BNL

Sri Lankan English O Level: Lever for Change. Practical Considerations.

Science.gov (United States)

Nanayakkara, Ethel; Webber, Richard

A discussion of the new Sri Lankan General Certificate of Education (GCE) O-Level standardized test of English focuses on how new ideas in testing have been implemented in the test and on their effect on classroom practice and the quality of English instruction. The discussion begins with a brief outline of the history and context in which the new…

Scientific, statistical, practical, and regulatory considerations in design space development.

Science.gov (United States)

Debevec, Veronika; Srčič, Stanko; Horvat, Matej

2018-03-01

The quality by design (QbD) paradigm guides the pharmaceutical industry towards improved understanding of products and processes, and at the same time facilitates a high degree of manufacturing and regulatory flexibility throughout the establishment of the design space. This review article presents scientific, statistical and regulatory considerations in design space development. All key development milestones, starting with planning, selection of factors, experimental execution, data analysis, model development and assessment, verification, and validation, and ending with design space submission, are presented and discussed. The focus is especially on frequently ignored topics, like management of factors and CQAs that will not be included in experimental design, evaluation of risk of failure on design space edges, or modeling scale-up strategy. Moreover, development of a design space that is independent of manufacturing scale is proposed as the preferred approach.

Impunity for International Terrorists? Key Legal Questions and Practical Considerations

Directory of Open Access Journals (Sweden)

Christophe Paulussen

2012-04-01

Full Text Available This Research Paper discusses several of the key questions related to the subject of impunity of international terrorists, taking both a fundamental and a more practical approach within the context of international law. First, it reflects on a number of core definitional and theoretical questions which have been pushed into the background of day‐to‐day reality, by the actual fight against terrorism. For instance: what does the concept of impunity entail exactly and which kinds of standards could be used in measuring impunity? Is it clear what falls under the header of international terrorism and can it in fact be argued that international terrorists enjoy impunity? In practical terms, the paper explores a number of questions related to the actual prosecution of terrorism. What are the obstacles that national prosecutors face every day when prosecuting suspects of international terrorism? To what extent does a rule that prima facie seems ideal to fight terrorism (aut dedere aut judicare: either extradite or prosecute apply to terrorist offences? And what is the role of international criminal law – and the international criminal tribunals – in fighting terrorism? The Paper concludes with a series of recommendations.

The Value of Literacy Practices

Science.gov (United States)

Esposito, Lucio; Kebede, Bereket; Maddox, Bryan

2015-01-01

The concepts of literacy events and practices have received considerable attention in educational research and policy. In comparison, the question of value, that is, "which literacy practices do people most value?" has been neglected. With the current trend of cross-cultural adult literacy assessment, it is increasingly important to…

Initial Freudian theories and practices: considerations on discovery of the unconscious

Directory of Open Access Journals (Sweden)

Daniel Polimeni Maireno

2014-06-01

Full Text Available This article compares some theoretical postulates and some clinical practices of early moments of Freudian works, favoring production periods of Studies on Hysteria and the Interpretation of Dreams. Other works are cited in order to complement. The study highlights the role of concepts such as repression, resistance and transference before the emergence of the concept of the unconscious – without which all previous lose much of their senses; suggests that, rather than a Freud’s willful disposition in the formulation of concept of the unconscious, what we see is, instead, his reluctance to admit such a concept, which justifies its late appearance compared to the others. We conclude, finally, that such reluctance itself, conveys a valuable model to psychoanalysts about how theoretical and practical developments of psychoanalysis must happens.

Good Practice Standards – a Regulation Tool

DEFF Research Database (Denmark)

Sørensen, Marie Jull

2013-01-01

The purpose of this article is to identify the considerations weighed in regulation with good practice standards. In this article, potential due process problems with regulation via legal standards are identified and compared to other considerations, which this regulation technique meets....

Use of the NASA Space Radiation Laboratory at Brookhaven National Laboratory to Conduct Charged Particle Radiobiology Studies Relevant to Ion Therapy.

Science.gov (United States)

Held, Kathryn D; Blakely, Eleanor A; Story, Michael D; Lowenstein, Derek I

2016-06-01

Although clinical studies with carbon ions have been conducted successfully in Japan and Europe, the limited radiobiological information about charged particles that are heavier than protons remains a significant impediment to exploiting the full potential of particle therapy. There is growing interest in the U.S. to build a cancer treatment facility that utilizes charged particles heavier than protons. Therefore, it is essential that additional radiobiological knowledge be obtained using state-of-the-art technologies and biological models and end points relevant to clinical outcome. Currently, most such ion radiotherapy-related research is being conducted outside the U.S. This article addresses the substantial contributions to that research that are possible at the NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory (BNL), which is the only facility in the U.S. at this time where heavy-ion radiobiology research with the ion species and energies of interest for therapy can be done. Here, we briefly discuss the relevant facilities at NSRL and how selected charged particle biology research gaps could be addressed using those facilities.

Design Considerations of Fast Kicker Systems for High Intensity Proton Accelerators

International Nuclear Information System (INIS)

Zhang, W.; Sandberg, J.; Parson, W.M.; Walstrom, P.; Murray, M.M.; Cook, E.; Hartouni, E.

2001-01-01

In this paper, we discuss the specific issues related to the design of the Fast Kicker Systems for high intensity proton accelerators. To address these issues in the preliminary design stage can be critical since the fast kicker systems affect the machine lattice structure and overall design parameters. Main topics include system architecture, design strategy, beam current coupling, grounding, end user cost vs. system cost, reliability, redundancy and flexibility. Operating experience with the Alternating Gradient Synchrotron injection and extraction kicker systems at Brookhaven National Laboratory and their future upgrade is presented. Additionally, new conceptual designs of the extraction kicker for the Spallation Neutron Source at Oak Ridge and the Advanced Hydrotest Facility at Los Alamos are discussed

Americans with Disabilities Act considerations for the practice of occupational medicine

Science.gov (United States)

St.clair, Steven; Shults, Theodore

1993-01-01

The Americans with Disabilities Act (ADA), although developed in the context of civil rights legislation, is likely to have notable impact on the practice of occupational medicine. The ADA contains provisions limiting the use of preplacement examinations to determinations of the capability to perform the essential functions of the job and of direct threat to the health and safety of the job applicant and others. The Title 1 employment provisions of the ADA established definitions and requirements similar to those found in section 504 of the Rehabilitation Act of 1973, as amended; leading cases that have been litigated under the Rehabilitation Act, as amended, are described. The limitations of available scientific and medical information related to determinations of job capability and direct threat and ramifications of the ADA on the practice of occupational medicine are discussed.

Some practical and theoretical considerations of personal alpha-particle dosimetry. Joint panel on occupational and environmental research for uranium production in Canada (JP-2)

Energy Technology Data Exchange (ETDEWEB)

Bigu, J [Department of Energy, Mines and Resources, Elliot Lake, ON (Canada). Elliot Lake Lab.; Duport, P [Atomic Energy Control Board, Ottawa, ON (Canada)

1990-12-31

The status of personal {alpha}-particle dosimetry in the uranium industry is presented. A brief description of personal dosimeters and prototypes is followed by some theoretical considerations regarding their practical use under steady-state and time-dependent field conditions. It is suggested that, at present, more effort should be placed on the evaluation of dosimeters than in the development of new ones. Also, more information should be gathered from countries which use personal {alpha}-particle dosimeters routinely. Furthermore, emphasis is recommended on comparison of personal dosimetry data with experimental data by area monitoring, using continuous monitoring systems, as well as with data by grab-sampling techniques. (author). 44 refs., 1 tab.

Some practical and theoretical considerations of personal alpha-particle dosimetry. Joint panel on occupational and environmental research for uranium production in Canada (JP-2)

International Nuclear Information System (INIS)

Bigu, J.

1989-01-01

The status of personal α-particle dosimetry in the uranium industry is presented. A brief description of personal dosimeters and prototypes is followed by some theoretical considerations regarding their practical use under steady-state and time-dependent field conditions. It is suggested that, at present, more effort should be placed on the evaluation of dosimeters than in the development of new ones. Also, more information should be gathered from countries which use personal α-particle dosimeters routinely. Furthermore, emphasis is recommended on comparison of personal dosimetry data with experimental data by area monitoring, using continuous monitoring systems, as well as with data by grab-sampling techniques. (author). 44 refs., 1 tab

Spirituality and medical practice: using the HOPE questions as a practical tool for spiritual assessment.

Science.gov (United States)

Anandarajah, G; Hight, E

2001-01-01

The relationship between spirituality and medicine has been the focus of considerable interest in recent years. Studies suggest that many patients believe spirituality plays an important role in their lives, that there is a positive correlation between a patient's spirituality or religious commitment and health outcomes, and that patients would like physicians to consider these factors in their medical care. A spiritual assessment as part of a medical encounter is a practical first step in incorporating consideration of a patient's spirituality into medical practice. The HOPE questions provide a formal tool that may be used in this process. The HOPE concepts for discussion are as follows: H--sources of hope, strength, comfort, meaning, peace, love and connection; O--the role of organized religion for the patient; P--personal spirituality and practices; E--effects on medical care and end-of-life decisions.

Simple and multiple linear regression: sample size considerations.

Science.gov (United States)

Hanley, James A

2016-11-01

The suggested "two subjects per variable" (2SPV) rule of thumb in the Austin and Steyerberg article is a chance to bring out some long-established and quite intuitive sample size considerations for both simple and multiple linear regression. This article distinguishes two of the major uses of regression models that imply very different sample size considerations, neither served well by the 2SPV rule. The first is etiological research, which contrasts mean Y levels at differing "exposure" (X) values and thus tends to focus on a single regression coefficient, possibly adjusted for confounders. The second research genre guides clinical practice. It addresses Y levels for individuals with different covariate patterns or "profiles." It focuses on the profile-specific (mean) Y levels themselves, estimating them via linear compounds of regression coefficients and covariates. By drawing on long-established closed-form variance formulae that lie beneath the standard errors in multiple regression, and by rearranging them for heuristic purposes, one arrives at quite intuitive sample size considerations for both research genres. Copyright © 2016 Elsevier Inc. All rights reserved.

Practical Considerations for Optic Nerve Estimation in Telemedicine

Energy Technology Data Exchange (ETDEWEB)

Karnowski, Thomas Paul [ORNL; Aykac, Deniz [ORNL; Chaum, Edward [ORNL; Giancardo, Luca [ORNL; Li, Yaquin [University of Tennessee, Knoxville (UTK); Tobin Jr, Kenneth William [ORNL

2009-01-01

The projected increase in diabetes in the United States and worldwide has created a need for broad-based, inexpensive screening for diabetic retinopathy (DR), an eye disease which can lead to vision impairment. A telemedicine network with retina cameras and automated quality control, physiological feature location, and lesion / anomaly detection is a low-cost way of achieving broad-based screening. In this work we report on the effect of quality estimation on an optic nerve (ON) detection method with a confidence metric. We report on an improvement of the fusion technique using a data set from an ophthalmologists practice then show the results of the method as a function of image quality on a set of images from an on-line telemedicine network collected in Spring 2009 and another broad-based screening program. We show that the fusion method, combined with quality estimation processing, can improve detection performance and also provide a method for utilizing a physician-in-the-loop for images that may exceed the capabilities of automated processing.

The Relativistic Heavy Ion Collider (RHIC) cryogenic system at Brookhaven National Laboratory: Review of the modifications and upgrades since 2002 and planned improvements

International Nuclear Information System (INIS)

Than, R.; Tuozzolo, Joseph; Sidi-Yekhlef, Ahmed; Ganni, Venkatarao; Knudsen, Peter; Arenius, Dana

2008-01-01

Brookhaven National Laboratory continues its multi-year program to improve the operational efficiency, reliability, and stability of the cryogenic system, which also resulted in an improved beam availability of the Relativistic Heavy Ion Collider (RHIC). This paper summarizes the work and changes made after each phase over the past four years to the present, as well as proposed future improvements. Power usage dropped from an initial 9.4 MW to the present 5.1 MW and is expected to drop below 5 MW after the completion of the remaining proposed improvements. The work proceeded in phases, balancing the Collider's schedule of operation, time required for the modifications and budget constraints. The main changes include process control, compressor oil removal and management, elimination of the use of cold compressors and two liquid-helium storage tanks, insulation of the third liquid-helium storage tank, compressor-bypass flow reduction and the addition of a load turbine (Joule-Thomson)

Development of an x-ray fluorescence microprobe at the National Synchrotron Light Source, Brookhaven National Laboratory: Early results: Comparison with data from other techniques

International Nuclear Information System (INIS)

Smith, J.V.; Rivers, M.L.; Sutton, S.R.; Jones, K.W.; Hanson, A.L.; Gordon, B.M.

1986-01-01

Theoretical predictions for the detection levels in x-ray fluorescence analysis with a synchrotron storage ring are being achieved experimentally at several laboratories. This paper is deliberately restricted to the state of development of the Brookhaven National Laboratory/University of Chicago instruments. Analyses at the parts per million (ppM) level are being made using white light apertured to 20 μm and an energy dispersive system. This system is particularly useful for elements with Z > 20 in materials dominated by elements with Z < 20. Diffraction causes an interference for crystalline materials. Development of a focusing microprobe for tunable monochromatic x-rays and a wavelength dispersive spectrometer (WDS) is delayed by problems in shaping an 8:1 focusing mirror to the required accuracy. Reconnaissance analyses with a wiggler source on the CHESS synchrotron have been made in the K spectrum up to Z = 80

Brookhaven Regional Energy Facility Siting Model (REFS): model development and application

Energy Technology Data Exchange (ETDEWEB)

Meier, P.; Hobbs, B.; Ketcham, G.; McCoy, M.; Stern, R.

1979-06-01

A siting methodology developed specifically to bridge the gap between regional-energy-system scenarios and environmental transport models is documented. Development of the model is described in Chapter 1. Chapter 2 described the basic structure of such a model. Additional chapters on model development cover: generation, transmission, demand disaggregation, the interface to other models, computational aspects, the coal sector, water resource considerations, and air quality considerations. These subjects comprise Part I. Part II, Model Applications, covers: analysis of water resource constraints, water resource issues in the New York Power Pool, water resource issues in the New England Power Pool, water resource issues in the Pennsylvania-Jersey-Maryland Power Pool, and a summary of water resource constraint analysis. (MCW)

Ethics of social media research: common concerns and practical considerations.

Science.gov (United States)

Moreno, Megan A; Goniu, Natalie; Moreno, Peter S; Diekema, Douglas

2013-09-01

Social media Websites (SMWs) are increasingly popular research tools. These sites provide new opportunities for researchers, but raise new challenges for Institutional Review Boards (IRBs) that review these research protocols. As of yet, there is little-to-no guidance regarding how an IRB should review the studies involving SMWs. The purpose of this article was to review the common risks inherent in social media research and consider how researchers can consider these risks when writing research protocols. We focused this article on three common research approaches: observational research, interactive research, and survey/interview research. Concomitant with these research approaches, we gave particular attention to the issues pertinent to SMW research, including privacy, consent, and confidentiality. After considering these challenges, we outlined key considerations for both researchers and reviewers when creating or reviewing SMW IRB protocols. Our goal in this article was to provide a detailed examination of relevant ethics and regulatory issues for both researchers and those who review their protocols.

Ethics of Social Media Research: Common Concerns and Practical Considerations

Science.gov (United States)

Goniu, Natalie; Moreno, Peter S.; Diekema, Douglas

2013-01-01

Abstract Social media Websites (SMWs) are increasingly popular research tools. These sites provide new opportunities for researchers, but raise new challenges for Institutional Review Boards (IRBs) that review these research protocols. As of yet, there is little-to-no guidance regarding how an IRB should review the studies involving SMWs. The purpose of this article was to review the common risks inherent in social media research and consider how researchers can consider these risks when writing research protocols. We focused this article on three common research approaches: observational research, interactive research, and survey/interview research. Concomitant with these research approaches, we gave particular attention to the issues pertinent to SMW research, including privacy, consent, and confidentiality. After considering these challenges, we outlined key considerations for both researchers and reviewers when creating or reviewing SMW IRB protocols. Our goal in this article was to provide a detailed examination of relevant ethics and regulatory issues for both researchers and those who review their protocols. PMID:23679571

Evidence-Based Practices in Special Education: Current Assumptions and Future Considerations

Science.gov (United States)

Russo-Campisi, Jacqueline

2017-01-01

Background: The research on evidence-based practices (EBP) in special education has shifted over the last decade from identifying efficacious interventions to exploring issues that impede implementation in the classroom. Common barriers to implementation include absence of training and resources, limited collaboration between researchers and…

Systems considerations in seismic margin evaluations

International Nuclear Information System (INIS)

Buttermer, D.R.

1987-01-01

Increasing knowledge in the geoscience field has led to the understanding that, although highly unlikely, it is possible for a nuclear power plant to be subjected to earthquake ground motion greater than that for which the plant was designed. While it is recognized that there are conservatisms inherent in current design practices, interest has developed in evaluating the seismic risk of operating plants. Several plant-specific seismic probabilistic risk assessments (SPRA) have been completed to address questions related to the seismic risk of a plant. The results from such SPRAs are quite informative, but such studies may entail a considerable amount of expensive analysis of large portions of the plant. As an alternative to an SPRA, it may be more practical to select an earthquake level above the design basis for which plant survivability is to be demonstrated. The principal question to be addressed in a seismic margin evaluation is: At what ground motion levels does one have a high confidence that the probability of seismically induced core damage is sufficiently low? In a seismic margin evaluation, an earthquake level is selected (based on site-specific geoscience considerations) for which a stable, long-term safe shutdown condition is to be demonstrated. This prespecified earthquake level is commonly referred to as the seismic margin earthquake (SME). The Electric Power Research Institute is currently supporting a research project to develop procedures for use by the utilities to allow them to perform nuclear plant seismic margin evaluations. This paper describes the systems-related aspects of these procedures

The theory–practice distinction and the complexity of practical knowledge

Directory of Open Access Journals (Sweden)

Bonnie Miller-McLemore

2016-08-01

Full Text Available Over the past few decades, theologians have recognised the value of practice but have been optimistic about the ease with which practice is incorporated into theology. People use all sorts of adjectives to characterise the complex relationship – ‘integrally related’, a ‘deeper reciprocity’, ‘bound up in thickly intertwined ways’ – but connecting the two is not as easy as these words suggest. This article returns to the age-old question about the relationship between theory and practice. But it studies this question from the angle of practice. Although many scholars have analysed the distinction between theory and practice as it functions conceptually, few have examined challenges in relating the two as they emerge in practice. The article argues that there is an inevitable distinction between theory and practice that receives considerably less attention and needs more understanding and even respect. It also argues that the discipline of practical theology adds a distinctive angle on this discussion because it considers how the concepts function practically.

Future management of hazardous wastes generated at Brookhaven National Laboratory, Upton, New York. Environmental assessment

International Nuclear Information System (INIS)

1994-09-01

This document assesses the potential environmental impacts of a variety of alternatives which could provide a Resource Conservation and Recovery Act (RCRA) permitted waste packaging and storage facility that would handle all hazardous, radioactive, and mixed wastes generated at Brookhaven National Laboratory (BNL) and would operate in full compliance with all federal, state, and local laws and regulations. Location of the existing Hazardous Waste Management Facility (HWMF) with respect to ground water and the site boundary, technical and capacity limitations, inadequate utilities, and required remediation of the area make the existing facility environmentally unacceptable for long term continued use. This Environmental Assessment (EA) describes the need for action by the Department of Energy (DOE). It evaluates the alternatives for fulfilling that need, including the alternative preferred by DOE, a no-action alternative, and other reasonable alternatives. The EA provides a general description of BNL and the existing environment at the current HWMF and alternative locations considered for a new Waste Management Facility (WMF). Finally, the EA describes the potential environmental impacts of the alternatives considered. The preferred alternative, also identified as Alternative D, would be to construct and operate a new WMF on land formerly occupied by barracks during Camp Upton operations, in an area north of Building 830 and the High Flux Beam Reactor/Alternating Gradient Synchrotron (AGS) recharge basins, east of North Railroad Street, and south of East Fifth Avenue. The purpose of this new facility would be to move all storage and transfer activities inside buildings and on paved and curbed areas, consolidate facilities to improve operations management, and provide improved protection of the environment

Technical considerations during disinfection by UV

International Nuclear Information System (INIS)

Ekhtiarzadeh, Z.; Sadeghpur, H.

2002-01-01

The use of new methods for treatment of water and wastewater in the country is one the rise and therefore the theoretical and practical knowledge of the industry's engineers should increase simultaneously. Ultraviolet is one of the new technologies used both for treatment of water as well as wastewater. The UV disinfection system consists of different components such as the lamp, ballast and the lamp fixtures. Each has a specification, which should be taken into account prior to design, order and purchase. The subject of price is also among the important considerations. The article presents figures cost comparison in various sections. It does not try to either approve or reject other disinfection systems such as chlorination, but the writer believes that any method should find its own practice and conditions of use, and the disinfection system designers should opt for the best system suited to their plans and avoid limiting themselves to a single one

Epithermal neutron beam design for neutron capture therapy at the Power Burst Facility and the Brookhaven Medical Research Reactor

International Nuclear Information System (INIS)

Wheeler, F.J.; Parsons, D.K.; Rushton, B.L.; Nigg, D.W.

1990-01-01

Nuclear design studies have been performed for two reactor-based epithermal neutron beams for cancer treatment by neutron capture therapy (NCT). An intermediate-intensity epithermal beam has been designed and implemented at the Brookhaven Medical Research Reactor (BMRR). Measurements show that the BMRR design predictions for the principal characteristics of this beam are accurate. A canine program for research into the biological effects of NCT is now under way at BMRR. The design for a high-intensity epithermal beam with minimal contamination from undesirable radiation components has been finalized for the Power Burst Facility (PBF) at the Idaho National Engineering Laboratory. This design will be implemented when it is determined that human NCT trials are advisable. The PBF beam will exhibit approximately an order of magnitude improvement in absolute epithermal flux intensity over that available in the BMRR, and its angular distribution and spectral characteristics will be more advantageous for NCT. The combined effects of beam intensity, angular distribution, spectrum, and contaminant level allow the desired tumor radiation dose to be delivered in much shorter times than are possible with the currently available BMRR beam, with a significant reduction (factor of 3 to 5) in collateral dose due to beam contaminants

Paediatricians, social media and blogs: Ethical considerations.

Science.gov (United States)

St-Laurent-Gagnon, Thérèse; Coughlin, Kevin W

2012-05-01

The use of blogs, Facebook and similar social networking sites is rapidly expanding and, when compared with e-mail, may be having a significantly different impact on the traditional doctor-patient relationship. Characteristics specific to these online platforms have major implications for professional relationships, including the 'Facebook effect' (the relative permanence of postings) and the 'online disinhibition effect'. The present practice point illustrates relevant ethical considerations and provides guidance to paediatricians and others concerning the prudent professional and personal use of social networking media.

Considerable variability of procedural sedation and analgesia practices for gastrointestinal endoscopic procedures in Europe

NARCIS (Netherlands)

Vaessen, Hermanus H B; Knape, Johannes T A

2016-01-01

Background/Aims: The use of moderate to deep sedation for gastrointestinal endoscopic procedures has increased in Europe considerably. Because this level of sedation is a risky medical procedure, a number of international guidelines have been developed. This survey aims to review if, and if so

Deadline pressure and human error: a study of human failures on a particle accelerator at Brookhaven National Laboratory

International Nuclear Information System (INIS)

Tiagha, E.A.

1982-01-01

The decline in industrial efficiency may be linked to decreased reliability of complex automatic systems. This decline threatens the viability of complex organizations in industrialized economies. Industrial engineering techniques that minimize system failure by increasing the reliability of systems hardware are well developed in comparison with those available to reduce human operator errors. The problem of system reliability and the associated costs of breakdown can be reduced if we understand how highly skilled technical personnel function in complex operations and systems. The purpose of this research is to investigate how human errors are affected by deadline pressures, technical communication and other socio-dynamic factors. Through the analysis of a technologically complex particle accelerator prototype at Brookhaven National Laboratory, two failure mechanisms: (1) physical defects in the production process and (2) human operator errors were identified. Two instruments were used to collect information on human failures: objective laboratory data and a human failure questionnaire. The results of human failures from the objective data were used to test for the deadline hypothesis and also to validate the human failure questionnaire. To explain why the human failures occurred, data were collected from a four-part, closed choice questionnaire administered to two groups of scientists, engineers, and technicians, working together against a deadline to produce an engineering prototype of a particle accelerator

Consideration of climate change on environmental impact assessment in Spain

Energy Technology Data Exchange (ETDEWEB)

Enríquez-de-Salamanca, Álvaro, E-mail: aenriquez@draba.org [Escuela de Doctorado, Universidad Nacional de Educación a Distancia, UNED, Draba Ingeniería y Consultoría Medioambiental, Cañada Nueva, 29, 28200 San Lorenzo de El Escorial (Spain); Martín-Aranda, Rosa M., E-mail: rmartin@ccia.uned.es [Departamento de Química Inorgánica y Química Técnica, Facultad de Ciencias, Universidad Nacional de Educación a Distancia, UNED, Paseo Senda del Rey, 9, 28040, Madrid (Spain); Díaz-Sierra, Rubén, E-mail: sierra@dfmf.uned.es [Departamento de Física Matemática y de Fluidos, Facultad de Ciencias, Universidad Nacional de Educación a Distancia, UNED, Paseo Senda del Rey, 9, 28040, Madrid (Spain)

2016-02-15

Most of the projects subject to environmental impact assessment (EIA) are closely related to climate change, as they contribute to or are affected by it. The growing certainty about climate change and its impacts makes its consideration an essential part of the EIA process, as well as in strategic environmental assessment (SEA). This paper examines how climate change (CC) has been taken into account in EIA in Spain through the analysis of 1713 environmental records of decision (RODs) of projects submitted for EIA. In 2013 Spain approved one of the most advanced laws in terms of CC consideration in environmental assessment, although it had not yet accumulated extensive practice on the issue. This contrasts with the situation of countries like Canada or the USA, which have a significant body of experience without specific legal requirements. Only 14% of the RODs analysed included references to CC, and in more than half of the cases it was a mere citation. Thermal power plants, which are subject to specific GHG regulations, show the highest consideration, while transport infrastructures, which are important contributors to CC, show a very low consideration. Almost all the references are related to their contribution to CC, while consideration of the effects of CC is minimal. The increasingly common incorporation of CC into SEA, should not imply its exclusion from EIA, because both processes have different aims and uses. Including the obligation to consider CC in the EIA regulations is highly desirable, but probably not enough without other measures, such as practical guidance, training and motivational programmes for practitioners and evaluators. But even these actions cannot ensure effective and adequate assessments of CC. Probably more resources should be spent on creating greater awareness in all the agents involved in EIA. - Highlights: • We analyse how the climate change is considered in EIA in Spain. • Few projects seriously assess climate change. �

Consideration of climate change on environmental impact assessment in Spain

International Nuclear Information System (INIS)

Enríquez-de-Salamanca, Álvaro; Martín-Aranda, Rosa M.; Díaz-Sierra, Rubén

2016-01-01

Most of the projects subject to environmental impact assessment (EIA) are closely related to climate change, as they contribute to or are affected by it. The growing certainty about climate change and its impacts makes its consideration an essential part of the EIA process, as well as in strategic environmental assessment (SEA). This paper examines how climate change (CC) has been taken into account in EIA in Spain through the analysis of 1713 environmental records of decision (RODs) of projects submitted for EIA. In 2013 Spain approved one of the most advanced laws in terms of CC consideration in environmental assessment, although it had not yet accumulated extensive practice on the issue. This contrasts with the situation of countries like Canada or the USA, which have a significant body of experience without specific legal requirements. Only 14% of the RODs analysed included references to CC, and in more than half of the cases it was a mere citation. Thermal power plants, which are subject to specific GHG regulations, show the highest consideration, while transport infrastructures, which are important contributors to CC, show a very low consideration. Almost all the references are related to their contribution to CC, while consideration of the effects of CC is minimal. The increasingly common incorporation of CC into SEA, should not imply its exclusion from EIA, because both processes have different aims and uses. Including the obligation to consider CC in the EIA regulations is highly desirable, but probably not enough without other measures, such as practical guidance, training and motivational programmes for practitioners and evaluators. But even these actions cannot ensure effective and adequate assessments of CC. Probably more resources should be spent on creating greater awareness in all the agents involved in EIA. - Highlights: • We analyse how the climate change is considered in EIA in Spain. • Few projects seriously assess climate change. �

An overview of age estimation in forensic anthropology: perspectives and practical considerations.

Science.gov (United States)

Márquez-Grant, Nicholas

2015-01-01

Information on methods of age estimation in physical anthropology, in particular with regard to age-at-death from human skeletal remains, is widely available in the literature. However, the practicalities and real challenges faced in forensic casework are not always highlighted. To provide a practitioner's perspective, regarding age estimation in forensic anthropology (both in the living as well as the dead), with an emphasis on the types of cases, the value of such work and its challenges and limitations. The paper reviews the current literature on age estimation with a focus on forensic anthropology, but it also brings the author's personal perspective derived from a number of forensic cases. Although much is known about what methods to use, but not always how to apply them, little attention has been given in the literature to the real practicalities faced by forensic anthropologists, for example: the challenges in different types of scenarios; how to report age estimations; responsibilities; and ethical concerns. This paper gathers some of these aspects into one overview which includes the value of such work and the practical challenges, not necessarily with the methods themselves, but also with regard to how these are applied in the different cases where age estimation is required.

A cylindrical drift chamber with azimuthal and axial position readout

International Nuclear Information System (INIS)

Bar-Yam, Z.; Cummings, J.P.; Dowd, J.P.; Eugenio, P.; Hayek, M.; Kern, W.; King, E.; Shenhav, N.; Chung, S.U.; Hackenburg, R.W.; Olchanski, C.; Weygand, D.P.; Willutzki, H.J.; Brabson, B.B.; Crittenden, R.R.; Dzierba, A.R.; Gunter, J.; Lindenbusch, R.; Rust, D.R.; Scott, E.; Smith, P.T.; Sulanke, T.; Teige, S.; Denisov, S.; Dushkin, A.; Kochetkov, V.; Lipaev, V.; Popov, A.; Shein, I.; Soldatov, A.; Anoshina, E.V.; Bodyagin, V.A.; Demianov, A.I.; Gribushin, A.M.; Kodolova, O.L.; Korotkikh, V.L.; Kostin, M.A.; Ostrovidov, A.I.; Sarycheva, L.I.; Sinev, N.B.; Vardanyan, I.N.; Yershov, A.A.; Adams, T.; Bishop, J.M.; Cason, N.M.; Sanjari, A.H.; LoSecco, J.M.; Manak, J.J.; Shephard, W.D.; Stienike, D.L.; Taegar, S.A.; Thompson, D.R.; Brown, D.S.; Pedlar, T.; Seth, K.K.; Wise, J.; Zhao, D.; Adams, G.S.; Napolitano, J.; Nozar, M.; Smith, J.A.; Witkowski, M.

1997-01-01

A cylindrical multiwire drift chamber with axial charge-division has been constructed and used in experiment E852 at Brookhaven National Laboratory. It serves as a trigger element and as a tracking device for recoil protons in π - p interactions. We describe the chamber's design considerations, details of its construction, electronics, and performance characteristics. (orig.)

A situated practice of ethics for participatory visual and digital methods in public health research and practice: a focus on digital storytelling.

Science.gov (United States)

Gubrium, Aline C; Hill, Amy L; Flicker, Sarah

2014-09-01

This article explores ethical considerations related to participatory visual and digital methods for public health research and practice, through the lens of an approach known as "digital storytelling." We begin by briefly describing the digital storytelling process and its applications to public health research and practice. Next, we explore 6 common challenges: fuzzy boundaries, recruitment and consent to participate, power of shaping, representation and harm, confidentiality, and release of materials. We discuss their complexities and offer some considerations for ethical practice. We hope this article serves as a catalyst for expanded dialogue about the need for high standards of integrity and a situated practice of ethics wherein researchers and practitioners reflexively consider ethical decision-making as part of the ongoing work of public health.

PRACTICE POINTS: AIDS Vaccine 2001: Looking to the Future ...

African Journals Online (AJOL)

PRACTICE POINTS: AIDS Vaccine 2001: Looking to the Future. ... The 3-day meeting in Philadelphia provided considerable information on the preclinical ... deal of effort and considerable expertise is now being directed towards dissecting the ...

Theoretical and Practical Considerations for Combating Mental Illness Stigma in Health Care.

Science.gov (United States)

Ungar, Thomas; Knaak, Stephanie; Szeto, Andrew C H

2016-04-01

Reducing the stigma and discrimination associated with mental illness is becoming an increasingly important focus for research, policy, programming and intervention work. While it has been well established that the healthcare system is one of the key environments in which persons with mental illnesses experience stigma and discrimination there is little published literature on how to build and deliver successful anti-stigma programs in healthcare settings, towards healthcare providers in general, or towards specific types of practitioners. Our paper intends to address this gap by providing a set of theoretical considerations for guiding the design and implementation of anti-stigma interventions in healthcare.

An audit of health products advertised for sale on chiropractic Web sites in Canada and consideration of these practices in the context of Canadian chiropractic codes of ethics and conduct.

Science.gov (United States)

Page, Stacey A; Grod, Jaroslaw P

2009-01-01

This study describes the extent to which chiropractors with Web sites practicing in Canada advertise health products for sale and considers this practice in the context of chiropractic codes of ethics and conduct. Chiropractic Web sites in Canada were identified using a public online business directory (Canada 411). The Web sites were searched, and an inventory of the health products for sale was taken. The influences of type of practice and province of practice on the sale of health product were assessed. Textual comments about health product marketing were summarized. National and provincial codes of ethics were reviewed, and the content on health product advertising was summarized. Two hundred eighty-seven Web sites were reviewed. Just more than half of the Web sites contained information on health products for sale (n = 158, 54%). Orthotics were advertised most often (n = 136 practices, 47%), followed by vitamins/nutritional supplements (n = 53, 18%), pillows and supports (n = 40, 14%), and exercise/rehabilitation products (n = 20, 7%). Chiropractors in solo or group chiropractic practices were less likely to advertise health products than those in multidisciplinary practice (P advertise nutritional supplements (P ethics and conduct varied in their guidelines regarding health product sales. Variations in codes of ethics and in the proportions of practitioners advertising health products for sales across the country suggest that opinions may be divided on the acceptability of health product sales. Such practices raise questions and considerations for the chiropractic profession.

Study on Students' Impression Data in Practical Training Using Text Mining Method-Analysis of Considerable Communication.

Science.gov (United States)

Teramachi, Hitomi; Sugita, Ikuto; Ino, Yoko; Hayashi, Yuta; Yoshida, Aki; Otsubo, Manami; Ueno, Anri; Katsuno, Hayato; Noguchi, Yoshihiro; Iguchi, Kazuhiro; Tachi, Tomoya

2017-09-01

We analyzed impression data and the scale of communication skills of students using text mining method to clarify which area a student was conscious of in communication in practical training. The results revealed that students tended to be conscious of the difference between practical hospital training and practical pharmacy training. In practical hospital training, specific expressions denoting relationships were "patient-visit", "counseling-conduct", "patient-counseling", and "patient-talk". In practical pharmacy training, specific expressions denoting relationships were "patient counseling-conduct", "story-listen", "patient-many", and "patient-visit". In practical hospital training, the word "patient" was connected to many words suggesting that students were conscious of a patient-centered communication. In practical pharmacy training, words such as "patient counseling", "patient", and "explanation" were placed in center and connected with many other words and there was an independent relationship between "communication" and "accept". In conclusion, it was suggested that students attempted active patient-centered communication in practical hospital training, while they were conscious of listening closely in patient counseling in practical pharmacy training.

PROJECT-SPECIFIC TYPE A VERIFICATION FOR THE HIGH FLUX BEAM REACTOR UNDERGROUND UTILITIES REMOVAL PHASE 3 TRENCH 1, BROOKHAVEN NATIONAL LABORATORY UPTON, NEW YORK

International Nuclear Information System (INIS)

Harpenau, E.M.

2010-01-01

The Oak Ridge Institute for Science and Education (ORISE) has reviewed the project documentation and data for the High Flux Beam Reactor (HFBR) Underground Utilities removal Phase 3; Trench 1 at Brookhaven National Laboratory (BNL) in Upton, New York. The Brookhaven Survey Group (BSG) has completed removal and performed Final Status Survey (FSS) of the 42-inch duct and 14-inch line in Trench 1 from Building 801 to the Stack. Sample results have been submitted as required to demonstrate that the cleanup goal of (le)15 mrem/yr above background to a resident in 50 years has been met. Four rounds of sampling, from pre-excavation to FSS, were performed as specified in the Field Sampling Plan (FSP) (BNL 2010a). It is the policy of the U.S. Department of Energy (DOE) to perform independent verifications of decontamination and decommissioning activities conducted at DOE facilities. ORISE has been designated as the organization responsible for this task for the HFBR Underground Utilities. ORISE, together with DOE, determined that a Type A verification of Trench 1 was appropriate based on recent verification results from Trenches 2, 3, 4, and 5, and the minimal potential for residual radioactivity in the area. The removal of underground utilities has been performed in three stages to decommission the HFBR facility and support structures. Phase 3 of this project included the removal of at least 200 feet of 36-inch to 42-inch duct from the west side to the south side of Building 801, and the 14-inch diameter Acid Waste Line that spanned from 801 to the Stack within Trench 1. Based on the pre-excavation sample results of the soil overburden, the potential for contamination of the soil surrounding the pipe is minimal (BNL 2010a). ORISE reviewed the gamma spectroscopy results for 14 FSS soil samples, four core samples, and one duplicate sample collected from Trench 1. Sample results for the radionuclides of concern were below the established cleanup goals. However, in sample PH-3

Librarian contributions to clinical practice guidelines.

Science.gov (United States)

Cruse, Peggy; Protzko, Shandra

2014-01-01

Librarians have become more involved in developing high quality systematic reviews. Evidence-based practice guidelines are an extension of systematic reviews and offer another significant area for librarian involvement. This column highlights opportunities and challenges for the librarian working on guideline panels and provides practical considerations for meaningful contributions to the guideline creation process.

Presenting practice financial information.

Science.gov (United States)

Webster, Lee Ann H

2007-01-01

Medical practice leadership teams, often consisting primarily of physicians with limited financial backgrounds, must make important business decisions and continuously monitor practice operations. In order to competently perform this duty, they need financial reports that are relevant and easy to understand. This article explores financial reporting and decision-making in a physician practice. It discusses reports and tools, such as ratios, graphs, and comparisons, that practices typically include in their reports. Because profitability and cash flow are often the most important financial considerations for physician practices, reports should generally focus on the impact of various activities and potential decisions upon these concerns. This article also provides communication tips for both those presenting practice financial information and those making the decisions. By communicating effectively, these leaders can best use financial information to improve decision-making and maximize financial performance.

Multi-MW accelerator target material properties under proton irradiation at Brookhaven National Laboratory linear isotope producer

Science.gov (United States)

Simos, N.; Ludewig, H.; Kirk, H.; Dooryhee, E.; Ghose, S.; Zhong, Z.; Zhong, H.; Makimura, S.; Yoshimura, K.; Bennett, J. R. J.; Kotsinas, G.; Kotsina, Z.; McDonald, K. T.

2018-05-01

The effects of proton beams irradiating materials considered for targets in high-power accelerator experiments have been studied using the Brookhaven National Laboratory's (BNL) 200 MeV proton linac. A wide array of materials and alloys covering a wide range of the atomic number (Z) are being scoped by the high-power accelerator community prompting the BNL studies to focus on materials representing each distinct range, i.e. low-Z, mid-Z and high-Z. The low range includes materials such as beryllium and graphite, the midrange alloys such as Ti-6Al-4V, gum metal and super-Invar and finally the high-Z range pure tungsten and tantalum. Of interest in assessing proton irradiation effects are (a) changes in physiomechanical properties which are important in maintaining high-power target functionality, (b) identification of possible limits of proton flux or fluence above which certain materials cease to maintain integrity, (c) the role of material operating temperature in inducing or maintaining radiation damage reversal, and (d) phase stability and microstructural changes. The paper presents excerpt results deduced from macroscopic and microscopic post-irradiation evaluation (PIE) following several irradiation campaigns conducted at the BNL 200 MeV linac and specifically at the isotope producer beam-line/target station. The microscopic PIE relied on high energy x-ray diffraction at the BNL NSLS X17B1 and NSLS II XPD beam lines. The studies reveal the dramatic effects of irradiation on phase stability in several of the materials, changes in physical properties and ductility loss as well as thermally induced radiation damage reversal in graphite and alloys such as super-Invar.

Proposed ultraviolet free-electron laser at Brookhaven National Laboratory: A source for time-resolved biochemical spectroscopy

International Nuclear Information System (INIS)

Johnson, E.D.; Sutherland, J.C.; Laws, W.R.

1992-01-01

Brookhaven National Laboratory is designing an ultraviolet free- electron laser (UV-FEL) user facility that will provide pico-second and sub-picosecond pulses of coherent ultraviolet radiation for wavelengths from 300 to 75 nm. Pulse width will be variable from abut 7 ps to ∼ 200 fs, with repetition rates as high as 10 4 Hz, single pulse energies > 1 mJ and hence peak pulse power >200 MW and average beam power > 10 W. The facility will be capable of ''pump-probe'' experiments utilizing the FEL radiation with: (1) synchronized auxiliary lasers, (2) a second, independently tunable FEL beam, or (3) broad-spectrum, high-intensity x-rays from the adjacent National Synchrotron Light Source. The UV-FEL consists of a high repetition rate recirculating superconducting linear accelerator which feeds pulses of electrons to two magnetic wigglers. Within these two devices, photons from tunable ''conventional'' laser would be frequency multiplied and amplified. By synchronously tuning the seed laser and modulating the energy of the electron beam, tuning of as much as 60% in wavelength is possible between alternating pulses supplied to different experimental stations, with Fourier transform limited resolution. Thus, up to four independent experiments may operate at one time, each with independent control of the wavelength and pulse duration. The UV-FEL will make possible new avenues of inquiry in time studies of diverse field including chemical, surface, and solid state physics, biology and materials science. The experimental area is scheduled to include a station dedicated to biological research. The complement of experimental and support facilities required by the biology station will be determined by the interests of the user community. 7 refs., 5 figs

Euthanasia of Cattle: Practical Considerations and Application

Science.gov (United States)

Shearer, Jan Keith

2018-01-01

type of bullet are important considerations when gunshot is used. When captive bolt is used, a penetrating captive bolt loaded with the appropriate powder charge and accompanied by a follow up (adjunctive) step to assure death are required. The success of physical methods also requires careful selection of the anatomic site for entry of a “free bullet” or “bolt” in the case of penetrating captive bolt. Disease eradication plans for animal health emergencies necessitate methods of euthanasia that will facilitate rapid and efficient depopulation of animals while preserving their welfare to the greatest extent possible. A portable pneumatic captive bolt device has been developed and validated as effective for use in mass depopulation scenarios. Finally, while most tend to focus on the technical aspects of euthanasia, it is extremely important that no one forget the human cost for those who may be required to perform the task of euthanasia on a regular basis. Symptoms including depression, grief, sleeplessness and destructive behaviors including alcoholism and drug abuse are not uncommon for those who participate in the euthanasia of animals. PMID:29673140

Best Practices for the Security of Radioactive Materials

Energy Technology Data Exchange (ETDEWEB)

Coulter, D.T.; Musolino, S.

2009-05-01

This work is funded under a grant provided by the US Department of Health and Human Services, Centers for Disease Control. The Department of Health and Mental Hygiene (DOHMH) awarded a contract to Brookhaven National Laboratory (BNL) to develop best practices guidance for Office of Radiological Health (ORH) licensees to increase on-site security to deter and prevent theft of radioactive materials (RAM). The purpose of this document is to describe best practices available to manage the security of radioactive materials in medical centers, hospitals, and research facilities. There are thousands of such facilities in the United States, and recent studies suggest that these materials may be vulnerable to theft or sabotage. Their malevolent use in a radiological-dispersion device (RDD), viz., a dirty bomb, can have severe environmental- and economic- impacts, the associated area denial, and potentially large cleanup costs, as well as other effects on the licensees and the public. These issues are important to all Nuclear Regulatory Commission and Agreement State licensees, and to the general public. This document outlines approaches for the licensees possessing these materials to undertake security audits to identify vulnerabilities in how these materials are stored or used, and to describe best practices to upgrade or enhance their security. Best practices can be described as the most efficient (least amount of effort/cost) and effective (best results) way of accomplishing a task and meeting an objective, based on repeatable procedures that have proven themselves over time for many people and circumstances. Best practices within the security industry include information security, personnel security, administrative security, and physical security. Each discipline within the security industry has its own 'best practices' that have evolved over time into common ones. With respect to radiological devices and radioactive-materials security, industry best practices

Best Practices for the Security of Radioactive Materials

International Nuclear Information System (INIS)

Coulter, D.T.; Musolino, S.

2009-01-01

This work is funded under a grant provided by the US Department of Health and Human Services, Centers for Disease Control. The Department of Health and Mental Hygiene (DOHMH) awarded a contract to Brookhaven National Laboratory (BNL) to develop best practices guidance for Office of Radiological Health (ORH) licensees to increase on-site security to deter and prevent theft of radioactive materials (RAM). The purpose of this document is to describe best practices available to manage the security of radioactive materials in medical centers, hospitals, and research facilities. There are thousands of such facilities in the United States, and recent studies suggest that these materials may be vulnerable to theft or sabotage. Their malevolent use in a radiological-dispersion device (RDD), viz., a dirty bomb, can have severe environmental- and economic- impacts, the associated area denial, and potentially large cleanup costs, as well as other effects on the licensees and the public. These issues are important to all Nuclear Regulatory Commission and Agreement State licensees, and to the general public. This document outlines approaches for the licensees possessing these materials to undertake security audits to identify vulnerabilities in how these materials are stored or used, and to describe best practices to upgrade or enhance their security. Best practices can be described as the most efficient (least amount of effort/cost) and effective (best results) way of accomplishing a task and meeting an objective, based on repeatable procedures that have proven themselves over time for many people and circumstances. Best practices within the security industry include information security, personnel security, administrative security, and physical security. Each discipline within the security industry has its own 'best practices' that have evolved over time into common ones. With respect to radiological devices and radioactive-materials security, industry best practices encompass

Deployment of Smart 3D Subsurface Contaminant Characterization at the Brookhaven Graphite Research Reactor

International Nuclear Information System (INIS)

Sullivan, T.; Heiser, J.; Kalb, P.; Milian, L.; Newson, C.; Lilimpakas, M.; Daniels, T.

2002-01-01

The Brookhaven Graphite Research Reactor (BGRR) Historical Site Assessment (BNL 1999) identified contamination inside the Below Grade Ducts (BGD) resulting from the deposition of fission and activation products from the pile on the inner carbon steel liner during reactor operations. Due to partial flooding of the BGD since shutdown, some of this contamination may have leaked out of the ducts into the surrounding soils. The baseline remediation plan for cleanup of contaminated soils beneath the BGD involves complete removal of the ducts, followed by surveying the underlying and surrounding soils, then removing soil that has been contaminated above cleanup goals. Alternatively, if soil contamination around and beneath the BGD is either non-existent/minimal (below cleanup goals) or is very localized and can be ''surgically removed'' at a reasonable cost, the BGD can be decontaminated and left in place. The focus of this Department of Energy Accelerated Site Technology Deployment (DOE ASTD) project was to determine the extent (location, type, and level) of soil contamination surrounding the BGD and to present this data to the stakeholders as part of the Engineering Evaluation/Cost Analysis (EE/CA) process. A suite of innovative characterization tools was used to complete the characterization of the soil surrounding the BGD in a cost-effective and timely fashion and in a manner acceptable to the stakeholders. The tools consisted of a tracer gas leak detection system that was used to define the gaseous leak paths out of the BGD and guide soil characterization studies, a small-footprint Geoprobe to reach areas surrounding the BGD that were difficult to access, two novel, field-deployed, radiological analysis systems (ISOCS and BetaScint) and a three-dimensional (3D) visualization system to facilitate data analysis/interpretation. All of the technologies performed as well or better than expected and the characterization could not have been completed in the same time or at

Students who are deaf and hard of hearing and use sign language: considerations and strategies for developing spoken language and literacy skills.

Science.gov (United States)

Nussbaum, Debra; Waddy-Smith, Bettie; Doyle, Jane

2012-11-01

There is a core body of knowledge, experience, and skills integral to facilitating auditory, speech, and spoken language development when working with the general population of students who are deaf and hard of hearing. There are additional issues, strategies, and challenges inherent in speech habilitation/rehabilitation practices essential to the population of deaf and hard of hearing students who also use sign language. This article will highlight philosophical and practical considerations related to practices used to facilitate spoken language development and associated literacy skills for children and adolescents who sign. It will discuss considerations for planning and implementing practices that acknowledge and utilize a student's abilities in sign language, and address how to link these skills to developing and using spoken language. Included will be considerations for children from early childhood through high school with a broad range of auditory access, language, and communication characteristics. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Practical considerations for maximizing heat production in a novel thermobrachytherapy seed prototype

Energy Technology Data Exchange (ETDEWEB)

Gautam, Bhoj; Warrell, Gregory; Shvydka, Diana; Ishmael Parsai, E., E-mail: e.parsai@utoledo.edu [University of Toledo Medical Center, 3000 Arlington Avenue, MS1151, Toledo, Ohio 43614 (United States); Subramanian, Manny [BEST Medical International, Inc., 7643 Fullerton Road, Springfield, Virginia 22153 (United States)

2014-02-15

images, and a preliminary experiment demonstrates thermal self-regulation and adequate heating of a tissue-mimicking phantom by seed prototypes. The effect of self-shielding of the seed against the external magnetic field is small, and only minor thermal stress is induced in heating of the seeds from room temperature to well above the seed operating temperature. With proper selection of magnetic field parameters, the thermal dose distribution of an arrangement of TB and hyperthermia-only seeds may be made to match with its radiation dose distribution. Conclusions: The presented analyses address several practical considerations for manufacturing of the proposed TB seeds and identify critical issues for the prototype implementation. The authors’ preliminary experiments demonstrate close agreement with the modeling results, confirming the feasibility of combining sources of heat and radiation into a single thermobrachytherapy seed.

Practical considerations for maximizing heat production in a novel thermobrachytherapy seed prototype

International Nuclear Information System (INIS)

Gautam, Bhoj; Warrell, Gregory; Shvydka, Diana; Ishmael Parsai, E.; Subramanian, Manny

2014-01-01

, and a preliminary experiment demonstrates thermal self-regulation and adequate heating of a tissue-mimicking phantom by seed prototypes. The effect of self-shielding of the seed against the external magnetic field is small, and only minor thermal stress is induced in heating of the seeds from room temperature to well above the seed operating temperature. With proper selection of magnetic field parameters, the thermal dose distribution of an arrangement of TB and hyperthermia-only seeds may be made to match with its radiation dose distribution. Conclusions: The presented analyses address several practical considerations for manufacturing of the proposed TB seeds and identify critical issues for the prototype implementation. The authors’ preliminary experiments demonstrate close agreement with the modeling results, confirming the feasibility of combining sources of heat and radiation into a single thermobrachytherapy seed

Development of Radhard VLSI electronics for SSC calorimeters

International Nuclear Information System (INIS)

Dawson, J.W.; Nodulman, L.J.

1989-01-01

A new program of development of integrated electronics for liquid argon calorimeters in the SSC detector environment is being started at Argonne National Laboratory. Scientists from Brookhaven National Laboratory and Vanderbilt University together with an industrial participants are expected to collaborate in this work. Interaction rates, segmentation, and the radiation environment dictate that front-end electronics of SSC calorimeters must be implemented in the form of highly integrated, radhard, analog, low noise, VLSI custom monolithic devices. Important considerations are power dissipation, choice of functions integrated on the front-end chips, and cabling requirements. An extensive level of expertise in radhard electronics exists within the industrial community, and a primary objective of this work is to bring that expertise to bear on the problems of SSC detector design. Radiation hardness measurements and requirements as well as calorimeter design will be primarily the responsibility of Argonne scientists and our Brookhaven and Vanderbilt colleagues. Radhard VLSI design and fabrication will be primarily the industrial participant's responsibility. The rapid-cycling synchrotron at Argonne will be used for radiation damage studies involving response to neutrons and charged particles, while damage from gammas will be investigated at Brookhaven. 10 refs., 6 figs., 2 tabs

Practical considerations for a second-order directional hearing aid microphone system

Science.gov (United States)

Thompson, Stephen C.

2003-04-01

First-order directional microphone systems for hearing aids have been available for several years. Such a system uses two microphones and has a theoretical maximum free-field directivity index (DI) of 6.0 dB. A second-order microphone system using three microphones could provide a theoretical increase in free-field DI to 9.5 dB. These theoretical maximum DI values assume that the microphones have exactly matched sensitivities at all frequencies of interest. In practice, the individual microphones in the hearing aid always have slightly different sensitivities. For the small microphone separation necessary to fit in a hearing aid, these sensitivity matching errors degrade the directivity from the theoretical values, especially at low frequencies. This paper shows that, for first-order systems the directivity degradation due to sensitivity errors is relatively small. However, for second-order systems with practical microphone sensitivity matching specifications, the directivity degradation below 1 kHz is not tolerable. A hybrid order directive system is proposed that uses first-order processing at low frequencies and second-order directive processing at higher frequencies. This hybrid system is suggested as an alternative that could provide improved directivity index in the frequency regions that are important to speech intelligibility.

Qualitative Parameters of Practice during University Studies

Science.gov (United States)

Stasiunaitiene, Egle; Norkute, Odeta

2011-01-01

In this article, relevance of practice during university studies is highlighted, as well as the main stages of its organisation, qualitative parameters, as well as criteria and indicators that validate them are defined. Discussion on the idea that taking into consideration qualitative parameters of organising practice as a component of studies…

Breast milk sharing via the internet: the practice and health and safety considerations.

Science.gov (United States)

Keim, Sarah A; McNamara, Kelly A; Jayadeva, Chenali M; Braun, Ashlea C; Dillon, Chelsea E; Geraghty, Sheela R

2014-08-01

To characterize the practice of breast milk sharing via the internet in the US and examine factors associated with participants' communication regarding potential health and safety risks. This cross-sectional study examined all original postings (n = 254) placed during 1 week in 2011 on four websites to facilitate the sharing of breast milk. Postings were characterized for intent and health and safety topics (i.e., selling vs. donating milk, hygiene/handling practices, infectious disease screening, diet/exercise habits, substance and pharmaceutical use, milk quality claims, price) communicated between milk providers and recipients. Approximately 69% of postings were providing milk and 31% were seeking milk; 47% included identifiers. Few provider postings reflected measures to potentially reduce risks to recipients: 20% mentioned using a healthy handling/hygiene practice, 11% offered specifics about infectious disease screening, 51% mentioned limiting/abstaining from 1+ substances. The presence of indications about handling/hygiene, diet/exercise, and abstaining from substances were strongly positively associated with each other (ORs 7.42-13.80), with the odds of selling (ORs 6.03-∞), and with making quality claims (ORs 3.14-13.54), but not with disease screening. One-fifth of recipients sought milk for a child with a medical condition or poor birth outcome. Most recipients (90%) did not specify any health and safety practices of a provider in their posting. Health behaviors and screening for diseases that may affect milk safety are not prominent topics in postings seeking to share milk. This lack of communication may exacerbate the health risks to recipient infants, especially infants at increased risk due to pre-existing health conditions.

Memory Interventions in the Criminal Justice System: Some Practical Ethical Considerations.

Science.gov (United States)

Cabrera, Laura Y; Elger, Bernice S

2016-03-01

In recent years, discussion around memory modification interventions has gained attention. However, discussion around the use of memory interventions in the criminal justice system has been mostly absent. In this paper we start by highlighting the importance memory has for human well-being and personal identity, as well as its role within the criminal forensic setting; in particular, for claiming and accepting legal responsibility, for moral learning, and for retribution. We provide examples of memory interventions that are currently available for medical purposes, but that in the future could be used in the forensic setting to modify criminal offenders' memories. In this section we contrast the cases of (1) dampening and (2) enhancing memories of criminal offenders. We then present from a pragmatic approach some pressing ethical issues associated with these types of memory interventions. The paper ends up highlighting how these pragmatic considerations can help establish ethically justified criteria regarding the possibility of interventions aimed at modifying criminal offenders' memories.

Considerations in using radiation dosimetry data in epidemiologic studies

International Nuclear Information System (INIS)

Hudson, D.H.; Beck, W.L.; Fry, S.A.; Lushbaugh, C.C.; Watson, J.

1983-01-01

From experience to date, it is concluded that cohorts can be divided into useable risk groups without need for extensive calculations of individual doses. Several possible risk group classification schemes are presented for use with standard methods of data analysis. The rationale, advantages, and disadvantages of each are discussed with respect to possible classification biases, and statistical and practical considerations. Data from a cohort of nuclear material workers are used to illustrate these dichotomous and ordinal schemes

Counseling Issues: Addressing Behavioral and Emotional Considerations in the Treatment of Communication Disorders.

Science.gov (United States)

Lieberman, Aaron

2018-02-06

Counseling is an important fundamental professional activity and an established component of the speech-language pathology/audiology scope of practice as documented by the American Speech-Language-Hearing Association (2004a, 2016a). Appropriate incorporation of counseling into practice can optimize service provision, help address comorbid behavioral and emotional reactions to communication disorders, and enhance prognosis. Practitioner insecurity in incorporating counseling into practice has been documented by Phillips and Mendel (2008), as well as Atkins (2007). This tutorial seeks to present general counseling constructs and treatment applications primarily utilizing a humanistic counseling perspective. This tutorial incorporated relevant publications from communication disorders and counseling psychology literature databases over a 3-year period. The tutorial evolved through interviews with practicing speech-language pathology practitioners and educators and was undertaken to provide transparency and clarity to support the assertions and recommendations offered. This tutorial organizes and presents general counseling considerations along with specific suggestions, which can help practitioners who are seeking to expand their understanding, skill, and confidence in incorporating counseling into their practice. The tutorial identifies some of the potential and impactful comorbid emotional and behavioral responses to experiencing a communication disorder and/or to the treatment process for the communication disorder issue(s). Theoretically grounded considerations for mitigating such potentially impactful responses are offered. Continued and enhanced efforts may be necessary to meet American Speech-Language-Hearing Association's mandate for universal incorporation of empirically supported counseling approaches and in advancing universal speech-language pathology/audiology training in this area. It is hoped that this tutorial serves as an initial guide for addressing

Deliberate interventions in the availability and circulation of practice elements

DEFF Research Database (Denmark)

Quitzau, Maj-Britt; Hoffmann, Birgitte

competences in relation to the heating system. Otherwise, the circulating ideas about comfort and the daily practices performed in the house remained unchanged. On the basis of these findings, we highlight how the considerations done by the urban government prior to the project and the negotiations undertaken...... of practices can help to inform policy makers in this regard, there is a need for more detailed insight into how such deliberate interventions are performed in practice and intersect with the availability and circulation of practice elements, among others. The aim of this paper is to explore the considerations...... area by setting up very strict requirements to the energy performance of the new buildings. Through qualitative interviews with the urban government, the building companies and the involved families, we have studied how this intervention hindered the circulation of certain practice elements, while...

The Psychological Benefits from Reconceptualizing Music-Making as Mindfulness Practice.

Science.gov (United States)

Steinfeld, Matthew; Brewer, Judson

2015-06-01

While the music psychology and education literatures have devoted considerable attention to how musical instrumentalists practice their instruments, less formal scholarly attention has been given in consideration of what it means to maintain a musical "practice" over time and across context. In this paper, the practice of mindfulness meditation is used as heuristic, arguing for a view of mindfulness meditation as a formalized de-specialization of the infinite number of other activities with which people can achieve mindfulness. Sitting meditation, requiring of one to observe the contents of their mind unmediated, can serve as a useful model for the musician in understanding the phenomenology of the music-making process and the "flow" states that can result from an embodied musical practice. Finally, reconceptualizing music-making as a mindfulness practice is considered with psychological and pedagogical implications relevant for developing musicians.

Structural considerations for solar installers : an approach for small, simplified solar installations or retrofits.

Energy Technology Data Exchange (ETDEWEB)

Richards, Elizabeth H.; Schindel, Kay (City of Madison, WI); Bosiljevac, Tom; Dwyer, Stephen F.; Lindau, William (Lindau Companies, Inc., Hudson, WI); Harper, Alan (City of Madison, WI)

2011-12-01

Structural Considerations for Solar Installers provides a comprehensive outline of structural considerations associated with simplified solar installations and recommends a set of best practices installers can follow when assessing such considerations. Information in the manual comes from engineering and solar experts as well as case studies. The objectives of the manual are to ensure safety and structural durability for rooftop solar installations and to potentially accelerate the permitting process by identifying and remedying structural issues prior to installation. The purpose of this document is to provide tools and guidelines for installers to help ensure that residential photovoltaic (PV) power systems are properly specified and installed with respect to the continuing structural integrity of the building.

Practical considerations for solar energy thermally enhanced photo-luminescence (TEPL) (Conference Presentation)

Science.gov (United States)

Kruger, Nimrod; Manor, Assaf; Kurtulik, Matej; Sabapathy, Tamilarasan; Rotschild, Carmel

2017-04-01

While single-junction photovoltaics (PV's) are considered limited in conversion efficiency according to the Shockley-Queisser limit, concepts such as solar thermo-photovoltaics aim to harness lost heat and overcome this barrier. We claim the novel concept of Thermally Enhanced Photoluminescence (TEPL) as an easier route to achieve this goal. Here we present a practical TEPL device where a thermally insulated photo-luminescent (PL) absorber, acts as a mediator between a photovoltaic cell and the sun. This high temperature absorber emits blue-shifted PL at constant flux, then coupled to a high band gap PV cell. This scheme promotes PV conversion efficiencies, under ideal conditions, higher than 62% at temperatures lower than 1300K. Moreover, for a PV and absorber band-gaps of 1.45eV (GaAs PV's) and 1.1eV respectively, under practical conditions, solar concentration of 1000 suns, and moderate thermal insulation; the conversion efficiencies potentially exceed 46%. Some of these practical conditions belong to the realm of optical design; including high photon recycling (PR) and absorber external quantum efficiency (EQE). High EQE values, a product of the internal QE of the active PL materials and the extraction efficiency of each photon (determined by the absorber geometry and interfaces), have successfully been reached by experts in laser cooling technology. PR is the part of emitted low energy photons (in relation to the PV band-gap) that are reabsorbed and consequently reemitted with above band-gap energies. PV back-reflector reflectivity, also successfully achieved by those who design the cutting edge high efficiency PV cells, plays a major role here.

Extended storage of low-level radioactive waste: an update

International Nuclear Information System (INIS)

Siskind, B.

1986-01-01

If a state or regional compact does not have adequate disposal capacity for low-level radioactive waste (LLRW), then extended storage of certain LLRW may be necessary. The Nuclear Regulatory Commission (NRC) has contracted with Brookhaven National Laboratory to address the technical issues of extended storage. The dual objectives of this study are (1) to provide practical technical assessments for NRC to consider in evaluating specific proposals for extended storage and (2) to help ensure adequate consideration by NRC, Agreement States, and licensees of potential problems that may arise from existing or proposed extended storage practices. The circumstances under which extended storage of LLRW would most likely result in problems during or after the extended storage period are considered and possible mitigative measures to minimize these problems are discussed. These potential problem areas include: (1) the degradation of carbon steel and polyethylene containers during storage and the subsequent need for repackaging (resulting in increased occupational exposure), (2) the generation of hazardous gases during storage, and (3) biodegradative processes in LLRW

Extended storage of low-level radioactive waste: an update

Energy Technology Data Exchange (ETDEWEB)

Siskind, B.

1986-01-01

If a state or regional compact does not have adequate disposal capacity for low-level radioactive waste (LLRW), then extended storage of certain LLRW may be necessary. The Nuclear Regulatory Commission (NRC) has contracted with Brookhaven National Laboratory to address the technical issues of extended storage. The dual objectives of this study are (1) to provide practical technical assessments for NRC to consider in evaluating specific proposals for extended storage and (2) to help ensure adequate consideration by NRC, Agreement States, and licensees of potential problems that may arise from existing or proposed extended storage practices. The circumstances under which extended storage of LLRW would most likely result in problems during or after the extended storage period are considered and possible mitigative measures to minimize these problems are discussed. These potential problem areas include: (1) the degradation of carbon steel and polyethylene containers during storage and the subsequent need for repackaging (resulting in increased occupational exposure), (2) the generation of hazardous gases during storage, and (3) biodegradative processes in LLRW.

One dozen considerations when working with women in substance abuse groups.

Science.gov (United States)

Bright, Charlotte Lyn; Osborne, Victoria A; Greif, Geoffrey L

2011-01-01

Women and men have different histories, presentations, and behaviors in substance abuse groups. Twelve considerations are offered for the beginning group leader when encountering women with substance abuse issues. These include understanding sexism, what brings women to treatment, and how women behave in group treatment. Implications for clinical practice with women in single-gender and mixed-gender groups are included.

Emergency medicine and general practice

OpenAIRE

Abela, Gunther

2005-01-01

Emergency Medicine and Immediate Medical Care are relatively new specialties. In Malta, there is quite a considerable area of overlap between these specialties and general practice. Indeed, the family physician is confronted with some sort of medical emergency quite regularly. The brief of this article is to go through recent developments in Emergency Medicine as applied to General Practice. The areas considered are Basic Life Support, Head Injury, Asthma, Anaphylaxis, Community Acquired Pneu...

Practical steps toward integrating economic, social and institutional elements in fisheries policy and management

DEFF Research Database (Denmark)

Stephenson, Robert L.; Benson, Ashleen J.; Brooks, Kate

2017-01-01

of explicit social, economic and institutional objectives; a general lack of process (frameworks, governance) for routine integration of all four pillars of sustainability; and a bias towards biological considerations. Practical integration requires a ‘systems’ approach with explicit consideration...... of strategic and operational aspects of management; multidisciplinary or transdisciplinary evaluations; practical objectives for the four pillars of sustainability; appropriate participation; and a governance system that is able to integrate these diverse considerations in management. We challenge all involved...... governance....

Nigerian Hospital Practice: Submissions

African Journals Online (AJOL)

It also publishes miscellaneous articles – hospital administration, business practice, accounting, Law for health practitioners and letters about published papers. All manuscript will be subject to blinded peer-review and the decision of the editor would be final. Articles submitted for consideration by the author should not have ...

Practical considerations for image-based PSF and blobs reconstruction in PET

International Nuclear Information System (INIS)

Stute, Simon; Comtat, Claude

2013-01-01

Iterative reconstructions in positron emission tomography (PET) need a model relating the recorded data to the object/patient being imaged, called the system matrix (SM). The more realistic this model, the better the spatial resolution in the reconstructed images. However, a serious concern when using a SM that accurately models the resolution properties of the PET system is the undesirable edge artefact, visible through oscillations near sharp discontinuities in the reconstructed images. This artefact is a natural consequence of solving an ill-conditioned inverse problem, where the recorded data are band-limited. In this paper, we focus on practical aspects when considering image-based point-spread function (PSF) reconstructions. To remove the edge artefact, we propose to use a particular case of the method of sieves (Grenander 1981 Abstract Inference New York: Wiley), which simply consists in performing a standard PSF reconstruction, followed by a post-smoothing using the PSF as the convolution kernel. Using analytical simulations, we investigate the impact of different reconstruction and PSF modelling parameters on the edge artefact and its suppression, in the case of noise-free data and an exactly known PSF. Using Monte-Carlo simulations, we assess the proposed method of sieves with respect to the choice of the geometric projector and the PSF model used in the reconstruction. When the PSF model is accurately known, we show that the proposed method of sieves succeeds in completely suppressing the edge artefact, though after a number of iterations higher than typically used in practice. When applying the method to realistic data (i.e. unknown true SM and noisy data), we show that the choice of the geometric projector and the PSF model does not impact the results in terms of noise and contrast recovery, as long as the PSF has a width close to the true PSF one. Equivalent results were obtained using either blobs or voxels in the same conditions (i.e. the blob�

Considerations for restoring temperate forests of tomorrow: Forest restoration, assisted migration, and bioengineering

Science.gov (United States)

Kas Dumroese; Mary I. Williams; John A. Stanturf; Brad St. Clair

2015-01-01

Tomorrow’s forests face extreme pressures from contemporary climate change, invasive pests, and anthropogenic demands for other land uses. These pressures, collectively, demand land managers to reassess current and potential forest management practices. We discuss three considerations, functional restoration, assisted migration, and bioengineering, which are currently...

Ethical considerations in sexual health research: A narrative review

Directory of Open Access Journals (Sweden)

Maryam Shirmohammadi

2018-01-01

Full Text Available Background: There is an assumption that sexual health research has great influence on the quality of human life through elevating sexual health standards, and their results will eliminate the burden of sexual health challenges on family relationships. The aim of this study was to review ethical considerations in sexual health research. Materials and Methods: This narrative review was conducted between January 1990 and December 2017 based on the five-step approach of York University. The keywords used to search for the studies included ethical issues, research, sexual health, reproductive health, and sensitive topics. The language of the literatures was English and the search process was performed on PubMed, Elsevier, Ovid, Springer, Google Scholar, ResearchGate, SAGE Publishing, ProQuest, WHO website, Kinsey Confidential, and Worldsexology. Results: After assessing the quality and eligibility of 94 articles, 13 were selected. The results of the present study showed that the most important ethical considerations were protecting the confidentiality and privacy of participants, obtaining informed consent, and paying attention to vulnerable people. Conclusions: The review of literature exhibited several considerations that sexual health researchers are faced with. In order to manage these considerations, the researcher should have sufficient understanding of them. The important matter is that strategies to manage these challenges should be completely rational and practical according to each context. These strategies can also be applied in other societies with great similarities in their context.

From research to practice: one organisational model for promoting research based practice.

Science.gov (United States)

Kitson, A

1997-01-01

This paper describes a framework used by the National Institute for Nursing in Oxford to integrate research, development and practice. With the increasing attention given to the topic of how research findings are implemented into clinical practice, it was felt important to share the challenges that have arisen in attempting to combine traditional research activities with more practice based development work. The emerging conceptual framework, structures and functions are described highlighting the variety of partnerships to be established in order to achieve the goal of integrating research into practice. While the underpinning principles of the framework--generating knowledge, implementing research into practice and evaluating the effectiveness of programmes--are not new, it is the way they have been combined within an organisational structure that could be helpful to others considering such a strategy. Both the strengths and weaknesses of the model are discussed, a number of conclusions drawn as to its robustness and consideration given to its replication.

Orthodontic practices in Australasia: practice activity.

Science.gov (United States)

Mathew, Rachael; Sampson, Wayne J; Spencer, A John

2005-05-01

To collect baseline data on practice types and services provided by orthodontists in Australia and New Zealand. A total of 510 questionnaires was sent and 258 were returned. The response rate was 53 per cent. The average age of respondents was 50 years (SD: 9.8 years) with female orthodontists being younger (Mean: 42.3 years; SD: 6.5). The ratio of responding female to male orthodontists was 1:8.8. Overall, more orthodontists were in solo private practice than associateships or partnerships. New Zealand orthodontists were more likely to be in associateships. Australian orthodontists had twice the number of practices (Mean: 2.4; SD: 1.4) than their New Zealand counterparts (Mean: 1.1; SD: 0.3). Orthodontists estimated they saw a mean of 21.3 (SD: 11.3) patients per day. Older orthodontists saw few patients in a day and spent fewer hours in any practice activity in a week. The mean waiting time for a consultation appointment in the private sector in New Zealand was nearly twice that in Australia. There was a significant association between male orthodontists and referral of patients by general dental practitioners. More than three quarters of respondents incorporated retention fees into the treatment fee. Overall, orthodontists were satisfied with the workload and did not want more orthodontists in their geographical area. This study provides a sound basis for consideration of challenges in practice and changes over time.

High performance work practices, innovation and performance

DEFF Research Database (Denmark)

Jørgensen, Frances; Newton, Cameron; Johnston, Kim

2013-01-01

Research spanning nearly 20 years has provided considerable empirical evidence for relationships between High Performance Work Practices (HPWPs) and various measures of performance including increased productivity, improved customer service, and reduced turnover. What stands out from......, and Africa to examine these various questions relating to the HPWP-innovation-performance relationship. Each paper discusses a practice that has been identified in HPWP literature and potential variables that can facilitate or hinder the effects of these practices of innovation- and performance...

Self-adapting the success rate when practicing math

NARCIS (Netherlands)

Jansen, B.R.J.; Hofman, A.D.; Savi, A.; Visser, I.; van der Maas, H.L.J.

2016-01-01

Use and benefits of the possibility to choose a success rate are studied in a math-practice application that is used by a considerable percentage of Dutch primary school children. Study 1 uses data that were collected with the application, using children's practice data (N = 40,329; grades 1–6).

An audit of health products and services marketed on chiropractic websites in Alberta and consideration of these practices in the context of chiropractic codes of conduct and ethics.

Science.gov (United States)

Page, Stacey A

2007-06-01

Chiropractic's success as a health care profession is evidenced in part by the rising number of practitioners. Paradoxically, this success may start to cost the profession, as the number of consumers may not be increasing proportionally. Fewer patients mean less income for practitioners. Some chiropractors are responding to these pressures by marketing health products, and services. To describe the extent to which Alberta chiropractors with websites sold health products and the extent to which fee discounts/service inducements were advertised. To consider these practices in the context of chiropractic codes of conduct and ethics. Chiropractic websites in the province of Alberta were identified using the online Telus Business Finder and cross-referenced with the Yellow Pages print directories. The websites were searched and an inventory of the health products for sale was recorded. Fee discounts and service inducements were also recorded. 56 websites were identified and reviewed. Just under two-thirds of the chiropractic websites surveyed contained information on health products for sale. Orthotics were sold most often (N = 29 practices; 51.8%), followed by pillows and supports (N = 15: 26.8%), vitamins/nutritional supplements (N = 15; 26.8%) and exercise/rehabilitation products (N = 10; 17.9%). Nine practices (16.1%) offered some type of inducement to potential customers. These included discounts on treatment packages (N = 2; 3.6%), free gait/ posture analyses (N = 2; 3.6%) and free general consultations with the chiropractors (N = 3; 5.4%) The marketing of health care products and services by chiropractors in Alberta is common. Such practices raise ethical considerations for the profession. Professional guidelines vary on the acceptability of these practices. Consumer and practitioner perspectives and practices regarding retailing need to be further examined.

Introduction of organic/hydro-organic matrices in inductively coupled plasma optical emission spectrometry and mass spectrometry: a tutorial review. Part II. Practical considerations.

Science.gov (United States)

Leclercq, Amélie; Nonell, Anthony; Todolí Torró, José Luis; Bresson, Carole; Vio, Laurent; Vercouter, Thomas; Chartier, Frédéric

2015-07-23

Inductively coupled plasma optical emission spectrometry (ICP-OES) and mass spectrometry (ICP-MS) are increasingly used to carry out analyses in organic/hydro-organic matrices. The introduction of such matrices into ICP sources is particularly challenging and can be the cause of numerous drawbacks. This tutorial review, divided in two parts, explores the rich literature related to the introduction of organic/hydro-organic matrices in ICP sources. Part I provided theoretical considerations associated with the physico-chemical properties of such matrices, in an attempt to understand the induced phenomena. Part II of this tutorial review is dedicated to more practical considerations on instrumentation, instrumental and operating parameters, as well as analytical strategies for elemental quantification in such matrices. Two important issues are addressed in this part: the first concerns the instrumentation and optimization of instrumental and operating parameters, pointing out (i) the description, benefits and drawbacks of different kinds of nebulization and desolvation devices and the impact of more specific instrumental parameters such as the injector characteristics and the material used for the cone; and, (ii) the optimization of operating parameters, for both ICP-OES and ICP-MS. Even if it is at the margin of this tutorial review, Electrothermal Vaporization and Laser Ablation will also be shortly described. The second issue is devoted to the analytical strategies for elemental quantification in such matrices, with particular insight into the isotope dilution technique, particularly used in speciation analysis by ICP-coupled separation techniques. Copyright © 2015 Elsevier B.V. All rights reserved.

Predicting Use of Outdoor Fall Prevention Strategies: Considerations for Prevention Practices.

Science.gov (United States)

Chippendale, Tracy

2018-01-01

Outdoor falls are just as common as indoor falls, but have received less attention in research and practice. Behavioral strategies play an important role in outdoor fall prevention. The purpose of this study was to examine predictors of strategy use. Backward stepwise regression was used to study factors associated with use of outdoor fall prevention strategies among a random sample ( N = 120) of community-dwelling seniors. Significant negative predictors of strategy use included higher education levels ( p outdoor fallers and nonfallers in the use of three different types of strategies ( ps outdoor fall prevention strategies. Further study of additional factors is warranted.

Employer Requirements to Work during Emergency Responses: Key Ethics Considerations.

Science.gov (United States)

Rutkow, Lainie; Taylor, Holly A; Powell, Tia

2017-03-01

Local health departments and their employees are at the forefront of emergency preparedness and response. Yet, recent studies have found that some local public health workers are unwilling to report to work in a variety of disaster scenarios. This can greatly compromise a response, as many local health departments need "all hands on deck" to effectively meet increased demands. To address these concerns, local health departments have employed varied policy strategies to ensure that employees do report to work. After describing different approaches taken by local health departments throughout the United States, we briefly identify and explore key ethics considerations that arise for local health departments when employees are required to report to work for emergency responses. We then discuss how these ethics considerations may inform local health department practices intended to promote a robust emergency response.

Multicultural and Diversity Considerations in the New "Code of Professional Ethics for Rehabilitation Counselors"

Science.gov (United States)

Cartwright, Brenda Y.; Fleming, Christine L.

2010-01-01

As the demographic transformation of the U.S. population continues, the challenges of multicultural and diversity-based considerations remain a central focus, as does the need to incorporate cultural competencies into the practice of rehabilitation. The Commission on Rehabilitation Counselor Certification's 2010 "Code of Professional Ethics for…

CMOS sigma-delta converters practical design guide

CERN Document Server

De la Rosa, Jose M

2013-01-01

A comprehensive overview of Sigma-Delta Analog-to-Digital Converters (ADCs) and a practical guide to their design in nano-scale CMOS for optimal performance. This book presents a systematic and comprehensive compilation of sigma-delta converter operating principles, the new advances in architectures and circuits, design methodologies and practical considerations - going from system-level specifications to silicon integration, packaging and measurements, with emphasis on nanometer CMOS implementation. The book emphasizes practical design issues - from high-level behavioural modelling i

Structuring group medical practices: shareholder and partnership agreements.

Science.gov (United States)

Gassman, A S

1992-01-01

This article is the second in a series addressing the structuring of group medical entities, shareholder relationships, and general representation factors. In this article, a number of the legal and business considerations for entering into shareholder and partnership agreements are discussed, and various types of practice structures and recommended group practice agreement provisions are described.

Evidence-based practice curriculum in allied health professions for teaching-research-practice nexus.

Science.gov (United States)

Asokan, G V

2012-11-01

Allied healthcare workers are from diverse professions and the key skill required is providing evidence-based care but this concept has not permeated enough for using it skillfully in their professions. A well structured curriculum in allied health professions is needed to strengthen concerted teaching, research, and practice to empower their professionals and make considerable differences in the lives of people by adopting evidence-based practice. Information sources for allied health professionals have relied on advice of their supervisors and colleagues, personal experiences, authoritative theory and texts for practice. Because of "research-practice" gap, often the use of evidence is not reflected in an individual day to day professional practice. Although allied health professionals work in resource and evidence challenged settings, there are certain barriers and facilitators, which need to be addressed. To implement practice-related research findings and uptake of evidence requires two essential components, namely, practical component and knowledge component. Research bench marking and research metrics for quality assurance and standardization through evidence-based practice will promote academic status and credibility of allied health profession. © 2012 Wiley Publishing Asia Pty Ltd and Chinese Cochrane Center, West China Hospital of Sichuan University.

Using a Locum Tenens in a Private Practice

Directory of Open Access Journals (Sweden)

Magda Slabbert

2013-12-01

Full Text Available Many medical practitioners in private practice use a locum tenens when they themselves are not available to practice. The locums are often appointed without consideration of the legal consequences or requirements. Legislation distinguishes between an employee and an independent contractor. If the locum is appointed as an employee the doctrine of vicarious liability comes into play which is not the case with an independent contractor. Contracts currently available to appoint a locum give the contracting parties a choice between being appointed as an employee or an independent contractor; this should be changed in that all locums should be appointed as independent contractors especially if the working of the Consumer Protection Act is also taken into consideration. Furthermore, according to the rules of the Health Professions Council of South Africa (HPCSA the onus to ensure that the locum tenens is registered and fit to practice, rests with the principal.

Eleven essential steps to purchasing or selling a medical practice.

Science.gov (United States)

Barrett, William

2014-01-01

Based on our experience in representing more than 100 doctors and medical specialists in practice sales and acquisitions, we have identified 11 key considerations important to a deal. There are several issues to consider while going through the process of buying or selling a practice including the implementation of a "letter of intent" as a first step rather than drafting a contract, securing a lease, and verifying the property is not in violation of the local zoning requirements. There are also considerations with regard to the patients, which range from how will the accounts receivable at the time of the closing be handled to who is responsible for the handling of continued treatment in an ongoing case after a deal is finalized. This article details these considerations and more.

Using the Environmental Kuznets Curve to evaluate energy policy: Some practical considerations

International Nuclear Information System (INIS)

Brown, Stephen P.A.; McDonough, Ian K.

2016-01-01

The Environmental Kuznets Curve (EKC) is a widely applied empirical model that is used to assess the effect of country's increased income on its emissions (such as CO 2 ). Typical estimation is of a reduced form model relating per capita emissions to per capita GDP (and sometimes to energy consumption) with an eye toward determining whether a country's per capita emissions increase or decrease with per capita GDP. In this article, we consider a number of practical issues in estimating and using the EKC for energy policy analysis. Proper estimation procedures should be used if the empirical work is to provide valid estimates of the EKC's shape. In addition, policymakers should proceed with caution when crafting policy on the basis of reduced form estimates of the EKC because the reduced form model provides limited insight into the policy implications of the relationship between income, energy consumption and emissions. - Highlights: • Many practical issues need to be considered when estimating the EKC. • Concerns expressed by some about use of polynomial functions are misplaced. • Confidence bands on EKC turning points should be provided. • Differences in short and long-run elasticities are not indicative of EKC shape. • Reduced-form estimates should be interpreted cautiously by policymakers.

Patient attributes warranting consideration in clinical practice guidelines, health workforce planning and policy

Directory of Open Access Journals (Sweden)

Segal Leonie

2011-09-01

Full Text Available Abstract Background In order for clinical practice guidelines (CPGs to meet their broad objective of enhancing the quality of care and supporting improved patient outcomes, they must address the needs of diverse patient populations. We set out to explore the patient attributes that are likely to demand a unique approach to the management of chronic disease, and which are crucial if evidence or services planning is to reflect clinic populations. These were incorporated into a new conceptual framework; using diabetes mellitus as an exemplar. Methods The patient attributes that informed the framework were identified from CPGs, the diabetes literature, an expert academic panel, and two cross-disciplinary panels; and agreed upon using a modified nominal group technique. Results Full consensus was reached on twenty-four attributes. These factors fell into one of three themes: (1 type/stage of disease, (2 morbid events, and (3 factors impacting on capacity to self-care. These three themes were incorporated in a convenient way in the workforce evidence-based (WEB model. Conclusions While biomedical factors are frequently recognised in published clinical practice guidelines, little attention is given to attributes influencing a person's capacity to self-care. Paying explicit attention to predictable threats to effective self-care in clinical practice guidelines, by drawing on the WEB model, may assist in refinements that would address observed disparities in health outcomes across socio-economic groups. The WEB model also provides a framework to inform clinical training, and health services and workforce planning and research; including the assessment of healthcare needs, and the allocation of healthcare resources.

Waste in Education: The Potential of Materiality and Practice

Science.gov (United States)

Jørgensen, Nanna Jordt; Madsen, Katrine Dahl; Laessøe, Jeppe

2018-01-01

This article explores how waste materials and waste practices figure in education, pointing to educational potentials of waste which have hitherto received little consideration in environmental and sustainability education practice and research. Building on empirical research on waste education in Danish schools and preschools, we discuss how an…

Integrating Motivational Interviewing and Brief Behavioral Activation Therapy: Theoretical and Practical Considerations

OpenAIRE

Balán, Iván C.; Lejuez, C. W.; Hoffer, Marcela; Blanco, Carlos

2016-01-01

Behavioral Activation and specifically the Brief Behavioral Activation Therapy for Depression (BATD) has a strong record of empirical support but its focus on practical out of session activation-based assignments can lead to poor levels of adherence if efforts to enhance motivation are not prioritized. Towards this end, this manuscript describes the assimilative integration of Motivational Interviewing (MI) and BATD to improve clinical outcomes by integrating MI's focus on building and mainta...

Practical considerations on frenectomy

Science.gov (United States)

Moldoveanu, Lucia; Badea, Florin Ciprian; Odor, Alin A.

2014-01-01

Besides surgically classical frenectomy, modern dentistry currently allows its approach by dental laser. Materials and Method: We proposed clinical observation of the results obtained by frenectomy with/without frenoplasty made by laser Er,Cr:YSGG 2780 nm. Results: The patients reported no pain, bleeding, swelling or major discomfort during the postoperative control of the following day. In terms of psycho-emotional reactions, both patients well behave well, the calm being given by no pain, bleeding, suture or edema. Discussions: The accuracy of this method, as well as the use of additional means of healing, allow satisfactory results both for patient and physician. Working parameters depend on the type of laser that is used, in our case Biolase Waterlase MD Turbo, regularly used in Toldimed Clinic in Constanta. Conclusions: Our study reveals that the possibilities regarding the surgical modeling of the lower lip frenulum are higher due to laser than the classical surgical approach. Moreover, a major role in the prevention of relapse by inappropriate healing is represented by the approach of frenectomy accompanied by frenuloplasty.

Derivation of residual radioactive material guidelines for 13 radionuclides present in Operable Unit IV at Brookhaven National Laboratory, Upton, New York

International Nuclear Information System (INIS)

Faillace, E.; Nimmagadda, M.; Yu, C.

1994-12-01

Residual radioactive material guidelines for 13 radionuclides (americium-241; cobalt-60; cesium-137; europium-152, -154, and -155; plutonium-238, -239, and -240; strontium-90; and uranium-234, -235, and -238) were derived for Operable Unit (OU) IV at Brookhaven National Laboratory. This site has been identified for remedial action under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980, as amended by the Superfund Amendments and Reauthorization Act of 1986. Single-nuclide guidelines were derived on the basis of the requirement that the 50-year committed effective dose equivalent to a hypothetical individual who lives or works in the immediate vicinity of OU IV should not exceed a dose constraint of 30 mrem/yr following remedial action for the current use and plausible future use scenarios or a dose limit of 100 mrem/yr for plausible but less likely future use scenarios. The US Department of Energy (DOE) residual radioactive material guideline computer code, RESRAD, was used in this evaluation; RESRAD implements the methodology described in the DOE manual for determining residual radioactive material guidelines. Four potential scenarios were considered; each assumed that, for a period of 1,000 years following remedial action, the site would be used without radiological restrictions. The four scenarios varied with regard to the type of site use, time spent at the site, and sources of food consumed

Exploring the Gaps in Practical Ethical Guidance for Animal Welfare Considerations of Field Interventions and Innovations Targeting Dogs and Cats

Science.gov (United States)

Tasker, Louisa; Getty, Susan F.; Briggs, Joyce R.; Benka, Valerie A.W.

2018-01-01

Simple Summary Large populations of domestic dogs and cats are found living, or in close association with humans. They are often targeted by field interventions or innovations to enhance their welfare or to reduce conflict with communities or wildlife. Ethical review is a cornerstone of responsible engagement that aims to promote animal and human wellbeing. For the review process to be robust, identifying and understanding the ethical dilemmas that may be encountered when working with dogs and cats in field contexts, together with their human communities and in multi-stakeholder partnerships would be advantageous. We explored existing guidance from other disciplines (regulated animal research, veterinary and human clinical trials, and research conducted on wildlife) and identified gaps in ethical frameworks that do not adequately address the specific and practical needs of nongovernmental or intergovernmental organizations, government agencies or independent researchers working with dogs and cats in field contexts. Navigating practical ethical concerns in complex, highly variable field contexts necessitates the development of additional resources that can better inform reliable ethical review processes, and subsequently enhance the humaneness and effectiveness of future interventions and innovations. Abstract Domestic dogs (Canis lupus familiaris) and cats (Felis silvestris catus) are common species targeted by nongovernmental or intergovernmental organizations, veterinarians and government agencies worldwide, for field interventions (e.g., population management, rabies vaccination programs) or innovations (e.g., development of technologies or pharmaceuticals to improve animal welfare). We have a moral responsibility to ensure that the conduct of this work is humane for dogs or cats, and to consider the human communities in which the animals live. Ethical review is widely accepted as being integral to responsible practice, and it is fundamental to good science that

Special considerations for electric submersible pump applications in underpressured reservoirs

International Nuclear Information System (INIS)

Powers, M.L.

1991-01-01

This paper investigates the effect of electric submersible pump performance tolerances and minor speed variations on the producing rate of wells completed in underpressured reservoirs, and presents ESP design considerations which are unique for this class of wells. These wells require considerable head to initiate flow and have relatively flat well-load curves. Pumps that operate near their maximum recommended rate have steep performance curves. it is shown that this minimizes the effect of an underperforming pump on producing rate. Equations are developed for calculating the effects of pump performance and speed. Application requires evaluating the slopes of the pump performance curve and well-load curve at design rate. Utility of these equations is demonstrated by practical examples. It is also demonstrated that flow-stall can easily occur in underpressured reservoir applications when pumps designed to operate near their minimum recommended rate are installed

Research design considerations for single-dose analgesic clinical trials in acute pain

DEFF Research Database (Denmark)

Cooper, Stephen A; Desjardins, Paul J; Turk, Dennis C

2016-01-01

This article summarizes the results of a meeting convened by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) on key considerations and best practices governing the design of acute pain clinical trials. We discuss the role of early phase clinical trials......, including pharmacokinetic-pharmacodynamic (PK-PD) trials, and the value of including both placebo and active standards of comparison in acute pain trials. This article focuses on single-dose and short-duration trials with emphasis on the perioperative and study design factors that influence assay...... sensitivity. Recommendations are presented on assessment measures, study designs, and operational factors. Although most of the methodological advances have come from studies of postoperative pain after dental impaction, bunionectomy, and other surgeries, the design considerations discussed are applicable...

Vital Involvement Practice: strengths as more than tools for solving problems.

Science.gov (United States)

Kivnick, Helen Q; Stoffel, Sharon A

2005-01-01

This article describes Vital Involvement Practice, a strength-based approach to clinical practice with elders, including those who are extremely frail. Using this approach, practitioners have been able to help elders increase later-life vitality and associated positive quality of life through: (1) systematic identification of individual strengths and assets (found both in the person and in the surrounding environment), and (2) consideration of these strengths alongside the individual and environmental deficits that are the subject of most geriatric practice. The approach utilizes original data-gathering tools (Occupational Profile; Life Strengths Interview Guide) and a stepwise, worksheet- structured consideration of these data in order to formulate action strategies for achieving client goals (Domain Scan; Domain Goals; Life Plan/Strategy). All elements of VIP emerged in pilot work with gerontological practitioners and their elder clients in such settings as: primary health care; government social service; subsidized senior housing; private clinical practice; community recreation. Limitations, implications, and promise are noted, with respect to practice and research.

29 CFR 780.140 - Place of performing the practice as a factor.

Science.gov (United States)

2010-07-01

... practice is performed with respect to products of farming operations, the controlling consideration is... rather than at what place or on whose land he produced them. Ordinarily, a practice performed by a farmer...

SU-E-I-68: Practical Considerations On Implementation of the Image Gently Pediatric CT Protocols

International Nuclear Information System (INIS)

Zhang, J; Adams, C; Lumby, C; Dillon, J; Woods, E; Richer, E

2014-01-01

Purpose: One limitation associated with the Image Gently pediatric CT protocols is practical implementation of the recommended manual techniques. Inconsistency as a result of different practice is a possibility among technologist. An additional concern is the added risk of data error that would result in over or underexposure. The Automatic Exposure Control (AEC) features automatically reduce radiation for children. However, they do not work efficiently for the patients of very small size and relative large size. This study aims to implement the Image Gently pediatric CT protocols in the practical setting while maintaining the use of AEC features for pediatric patients of varying size. Methods: Anthropomorphological abdomen phantoms were scanned in a CT scanner using the Image Gently pediatric protocols, the AEC technique with a fixed adult baseline, and automatic protocols with various baselines. The baselines were adjusted corresponding to patient age, weight and posterioranterior thickness to match the Image Gently pediatric CT manual techniques. CTDIvol was recorded for each examination. Image noise was measured and recorded for image quality comparison. Clinical images were evaluated by pediatric radiologists. Results: By adjusting vendor default baselines used in the automatic techniques, radiation dose and image quality can match those of the Image Gently manual techniques. In practice, this can be achieved by dividing pediatric patients into three major groups for technologist reference: infant, small child, and large child. Further division can be done but will increase the number of CT protocols. For each group, AEC can efficiently adjust acquisition techniques for children. This implementation significantly overcomes the limitation of the Image Gently manual techniques. Conclusion: Considering the effectiveness in clinical practice, Image Gently Pediatric CT protocols can be implemented in accordance with AEC techniques, with adjusted baselines, to

Ethical Considerations of Preclinical Testing

Directory of Open Access Journals (Sweden)

Allen Goldenthal

2015-12-01

Full Text Available The numbers of animal tests being conducted are on a sharp incline.  Much of this increase is directly due to our ability to generate transgenic models and knock-outs, thereby increasing the validity of the animal model but not necessarily correlating directly with any translational medical benefits to the human counterpart.  In spite of our best efforts, there still exist species differences that prevent the application directly from animal to human, and in some examples having a completely different and adverse effect from that seen in the animal model. There are several ways in which we can improve the opportunity for a positive test outcome and at the same time reduce the animal usage which is associated with our current animal testing practices. The benefit of the 3R’s is that they encourage us not only to avoid wastage of life but that they require us to provide considerable foresight and extrapolated thought before directly engaging in the preclinical testing phase.

Best Practices for Management of Biocontaminated Waste ...

Science.gov (United States)

Report The purpose of these best practices is to provide federal, state, territorial, and local waste management entities information on techniques and methodologies that have the potential to improve the handling and management of biocontaminated waste streams after a biological agent incident. These best practices are intended to be general in nature serving as a resource to a variety of biological agents in a variety of situations; however, these best practices also present a specific homeland security scenario – a biological attack with Bacillus anthracis (B. anthracis) – to help illustrate specific waste management considerations.

Parental Perceptions and Practices toward Childhood Asthma

OpenAIRE

Abu-Shaheen, Amani K.; Nofal, Abdullah; Heena, Humariya

2016-01-01

Introduction. Parental perceptions and practices are important for improving the asthma outcomes in children; indeed, evidence shows that parents of asthmatic children harbor considerable misperceptions of the disease. Objective. To investigate the perceptions and practices of parents toward asthma and its management in Saudi children. Methods. Using a self-administered questionnaire, a two-stage cross-sectional survey of parents of children aged between 3 and 15 years, was conducted from sch...

Considerations for Clinical Neuropsychological Evaluation in Amyotrophic Lateral Sclerosis.

Science.gov (United States)

Woolley, Susan C; Rush, Beth K

2017-11-01

The clinical neuropsychologist has the opportunity to be uniquely involved in the evaluation and treatment of individuals with amyotrophic lateral sclerosis (ALS). We review the current literature that defines cognitive and behavioral symptoms in ALS, including current knowledge of the neuropathological and genetic underpinning for these symptoms. There are unique considerations for clinical neuropsychological evaluation and clinical research in ALS and we highlight these in this review. Specifically, we shed light on special factors that contribute to our understanding of cognitive and behavioral impairment in ALS, including co-morbid symptoms, differential diagnosis, and considerations for longitudinal tracking of phenotypes. We discuss the rationale for proposing a specific approach to such as cognitive screening, test selection, response modality consideration, and test-retest intervals. With this didactic overview, the clinical neuropsychologist has the potential to learn more about the heterogeneous presentation of motor and neuropsychological symptoms in ALS. Furthermore, the reader has the opportunity to understand what it takes to develop a valid assessment approach particularly when the phenotype of ALS remains undefined in some regards. This clinical practice review sets the stage for the clinical neuropsychologist to further contribute to our clinical and scientific understanding of ALS and cognition. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Generalized causal mediation and path analysis: Extensions and practical considerations.

Science.gov (United States)

Albert, Jeffrey M; Cho, Jang Ik; Liu, Yiying; Nelson, Suchitra

2018-01-01

Causal mediation analysis seeks to decompose the effect of a treatment or exposure among multiple possible paths and provide casually interpretable path-specific effect estimates. Recent advances have extended causal mediation analysis to situations with a sequence of mediators or multiple contemporaneous mediators. However, available methods still have limitations, and computational and other challenges remain. The present paper provides an extended causal mediation and path analysis methodology. The new method, implemented in the new R package, gmediation (described in a companion paper), accommodates both a sequence (two stages) of mediators and multiple mediators at each stage, and allows for multiple types of outcomes following generalized linear models. The methodology can also handle unsaturated models and clustered data. Addressing other practical issues, we provide new guidelines for the choice of a decomposition, and for the choice of a reference group multiplier for the reduction of Monte Carlo error in mediation formula computations. The new method is applied to data from a cohort study to illuminate the contribution of alternative biological and behavioral paths in the effect of socioeconomic status on dental caries in adolescence.

Proposing a Center on Aging and Well-Being: Research, Education, and Practice Considerations

Science.gov (United States)

Lindenbach, Jeannette M.; Jessup-Falcioni, Heather

2016-01-01

This environmental scan aimed to discover research interests and educational needs of faculty, graduate, and undergraduate students to inspire research, education, and practice in the development of a center on aging and well-being for older adults. The scan consisted of a search of university faculty and researchers regarding research on aging; a…

Journalism in new clothes: considerations on the identity and professional practice based on Prêmio Imprensa Embratel

Directory of Open Access Journals (Sweden)

Milton Julio Faccin

2013-12-01

Full Text Available This article addresses some ideas about current journalistic practices and their consequent interventions in redefining the professional ethos of the business environment in the Brazilian press. As in other professions, the journalistic identity results from a network of social representations that, through a set of concepts, techniques and procedures, reproduces and is produced by everyday practices originated in their field. Among these practices are the awards granted to professionals. Certain awards have become so relevant that they are taken as benchmarks for good professional practice and, concomitantly, evidence of journalistic practice paradigms. This is the case of Prêmio Imprensa Embratel, chosen here as the object of study. The choice is guided not only by the sponsoring company, but also by its connection with the associations. With different aspects from the most traditional prize in the field, Prêmio Esso de Jornalismo, Prêmio Imprensa Embratel emphasizes the ramifications of the reportage practice, through the categories that do not concern solely on the content of the coverages, but also seek recognition as a kind of prize made by and for journalists.

Cardiovascular diseases in dental practice : Practical considerations

OpenAIRE

Margaix Muñoz, María; Jiménez Soriano, Yolanda; Poveda Roda, Rafael; Sarrión Pérez, María Gracia

2008-01-01

Coronary heart disease is the principal cause of death in the industrialized world. Its most serious expression, acute myocardial infarction, causes 7.2 million deaths each year worldwide, and it is estimated that 20% of all people will suffer heart failure in the course of their lifetime. The control of risk cardiovascular factors, including arterial hypertension, obesity and diabetes mellitus is the best way to prevent such diseases. The most frequent and serious cardiovascular emergenc...

Transplanting the Body: Preliminary Ethical Considerations.

Science.gov (United States)

Miller, Lantz Fleming

2017-11-01

A dissociated area of medical research warrants bioethical consideration: a proposed transplantation of a donor's entire body, except head, to a patient with a fatal degenerative disease. The seeming improbability of such an operation can only underscore the need for thorough bioethical assessment: Not assessing a case of such potential ethical import, by showing neglect instead of facing the issue, can only compound the ethical predicament, perhaps eroding public trust in ethical medicine. This article discusses the historical background of full-body transplantation, documents the seriousness of its current pursuit, and builds an argument for why prima facie this type of transplant is bioethically distinct. Certainly, this examination can only be preliminary, indicating what should be a wide and vigorous discussion among practitioners and ethicists. It concludes with practical suggestions for how the medical and bioethics community may proceed with ethical assessment.

Some considerations in the handling of fluorine and the chlorine fluorides

International Nuclear Information System (INIS)

Farrar, R.L. Jr.; Barber, E.J.

1979-01-01

This paper reviews many considerations in the safe handling of fluorine and the chlorine fluorides. The physical, chemical, and toxicological properties of the materials are reviewed. Proper choice of materials of construction and materials in contact with the active gases are considered. The survey includes safe practices in design and operation of experiments and processes. Soda lime traps and caustic scrubbing are reviewed for fluorine disposal methods. Finally some explosive reactions and explosive situations are discussed

Diet and Blood Pressure Control in Chinese Canadians: Cultural Considerations.

Science.gov (United States)

Zou, Ping

2017-04-01

Hypertension is highly prevalent in Chinese Canadians and diet has been identified as an important modifiable risk factor for hypertension. The current anti-hypertensive dietary recommendations in hypertension care guidelines lack examination of cultural factors, are not culturally sensitive to ethnic populations, and cannot be translated to Chinese Canadian populations without cultural considerations. Guided by Leininger's Sunrise Model of culture care theory, this paper investigates how cultural factors impact Chinese Canadians' dietary practice. It is proposed that English language proficiency, health literacy, traditional Chinese diet, migration and acculturation, and Traditional Chinese Medicine influence Chinese Canadians' dietary practices. A culturally congruent nursing intervention should be established and tailored according to related cultural factors to facilitate Chinese Canadians' blood pressure control. In addition, further study is needed to test the model adapted from Sunrise Model and understand its mechanism.

Connecting to Experience: High-Impact Practices for Leadership Development.

Science.gov (United States)

Priest, Kerry L; Clegorne, Nicholas A

2015-01-01

Leadership educators can leverage high-impact experiences to enhance student leadership development. This chapter describes three key practices--sociocultural conversations with peers, mentoring, and membership in off-campus organizations--as levers of leadership learning. Illustrations of the practice in context and reflections from practitioners and students are also included. The chapter concludes with considerations of context, developmental readiness, and best practices of experiential education. © 2015 Wiley Periodicals, Inc., A Wiley Company.

Capital budgeting practices in Indian companies

Directory of Open Access Journals (Sweden)

Roopali Batra

2017-03-01

Full Text Available The volatility of the global economy, changing business practices, and academic developments have created a need to re-examine Indian corporate capital budgeting practices. Our research is based on a sample of 77 Indian companies listed on the Bombay Stock Exchange. Results reveal that corporate practitioners largely follow the capital budgeting practices proposed by academic theory. Discounted cash flow techniques of net present value and internal rate of return and risk adjusted sensitivity analysis are most popular. Weighted average cost of capital as cost of capital is most favoured. Nevertheless, the theory-practice gap remains in adoption of specialised techniques of real options, modified internal rate of return (MIRR, and simulation. Non-financial criteria are also given due consideration in project selection.

Surgical practice in a maximum security prison – unique and ...

African Journals Online (AJOL)

The practice of general surgery in a prison population differs considerably from that in a general surgical practice. We audited surgical consultations at the Mangaung Correctional Centre from December 2003 to April 2009. We found a high incidence of foreign object ingestion and anal pathology. Understanding the medical ...

A Practical Approach for Parameter Identification with Limited Information

DEFF Research Database (Denmark)

Zeni, Lorenzo; Yang, Guangya; Tarnowski, Germán Claudio

2014-01-01

A practical parameter estimation procedure for a real excitation system is reported in this paper. The core algorithm is based on genetic algorithm (GA) which estimates the parameters of a real AC brushless excitation system with limited information about the system. Practical considerations are ...... parameters. The whole methodology is described and the estimation strategy is presented in this paper....

Ethical considerations regarding the implementation of new technologies and techniques in surgery.

Science.gov (United States)

Strong, Vivian E; Forde, Kenneth A; MacFadyen, Bruce V; Mellinger, John D; Crookes, Peter F; Sillin, Lelan F; Shadduck, Phillip P

2014-08-01

Ethical considerations relevant to the implementation of new surgical technologies and techniques are explored and discussed in practical terms in this statement, including (1) How is the safety of a new technology or technique ensured?; (2) What are the timing and process by which a new technology or technique is implemented at a hospital?; (3) How are patients informed before undergoing a new technology or technique?; (4) How are surgeons trained and credentialed in a new technology or technique?; (5) How are the outcomes of a new technology or technique tracked and evaluated?; and (6) How are the responsibilities to individual patients and society at large balanced? The following discussion is presented with the intent to encourage thought and dialogue about ethical considerations relevant to the implementation of new technologies and new techniques in surgery.

Tests of an environmental and personnel safe cleaning process for Brookhaven National Laboratory accelerator and storage ring components

International Nuclear Information System (INIS)

Foerster, C.L.; Lanni, C.; Lee, R.; Mitchell, G.; Quade, W.

1997-01-01

A large measure of the successful operation of the National Synchrotron Light Source (NSLS) at Brookhaven National Laboratory (BNL) for over a decade can be attributed to the cleaning of its ultrahigh vacuum (UHV) components during and after construction. A new UHV cleaning process, which has to be environmentally and personnel safe, is needed to replace the harsh, unfriendly process which is still in use. Dow Advanced Cleaning Systems was contracted to develop a replacement process without the use of harsh chemicals and which must clean vacuum surfaces as well as the existing process. Acceptance of the replacement process was primarily based on photon stimulated desorption (PSD) measurements of beam tube samples run on NSLS beam line U10B. One meter long beam tube samples were fabricated from aluminum, 304 stainless steel, and oxygen-free copper. Initially, coupon samples were cleaned and passed preliminary testing for the proposed process. Next, beam tube samples of each material were cleaned, and the PSD measured on beam line U10B using white light with a critical energy of 487 eV. Prior to cleaning, the samples were contaminated with a mixture of cutting oils, lubricants, vacuum oils, and vacuum grease. The contaminated samples were then baked. Samples of each material were also cleaned with the existing process after the same preparation. Beam tube samples were exposed to between 10 22 and 10 23 photons per meter for a PSD measurement. Desorption yields for H 2 , CO, CO 2 , CH 4 , and H 2 O are reported for both the existing cleaning and for the replacement cleaning process. Preliminary data, residual gas scans, and PSD results are given and discussed. The new process is also compared with new cleaning methods developed in other laboratories. After modification, the new UHV cleaning process was accepted by BNL

How to build the practice you want, not just the practice that walks through the door.

Science.gov (United States)

Jackson, Rem

2013-01-01

The first step in transforming your patient mix is to recognize that it is appropriate to prefer to see a specific type of patient over other types. You may enjoy working in a particular practice niche more than others, and there may be financial considerations as well. The second step is to change your marketing so that it focuses on your preferred, or "perfect," patient. This strategy will allow you to build a patient database that will enable you to change, over time, the type of patients you are seeing in your practice.

Aerial radiological survey of the Brookhaven National Laboratory and surrounding area, Upton, New York. Date of survey: June 1983

International Nuclear Information System (INIS)

Hobaugh, J.L.

1985-02-01

An aerial radiological survey was performed from 11 to 13 June 1983, over approximately a 64-square-kilometer (25-square-mile) area surrounding the Brookhaven National Laboratory (BNL). BNL is located in the center of Suffolk County, Long Island, New York. All gamma radiation data were collected by flying east-west lines spaced 76 meters (250 feet) apart at an altitude of 46 meters (150 feet) above ground level. Count rates obtained from the aerial platform were converted to exposure rates at 1 meter above the ground. The average background exposure rate in the survey area ranged from 5 to 10 microroentgens per hour (μR/h). The reported exposure rate values include an estimated cosmic ray contribution of 4.0 μR/h. Ground-based measurements made during the same time period were compared to the aerial survey results. Pressurized ion chamber readings and soil samples were taken from two locations within the aerial survey boundaries. Exposure rate values obtained from these measurement techniques were in agreement with those obtained from the aerial data. A total of 23 areas of man-made radioactivity were identified. The dominant isotopes found over these areas were cesium-137, sodium-22, manganese-54, and cobalt-60. A similar survey was conducted in May 1980. The 1983 survey results were similar to the 1980 results. Three areas of low level man-made activity were not reproduced by the 1983 data. Ten new areas were detected. The major difference occurred because of the increased sensitivity and spatial reduction brought on by lowering the altitude and decreasing the line spacing. 8 refs., 28 figs., 4 tabs

Safety issues in established predisposal waste management practices

International Nuclear Information System (INIS)

Thomas, W.

2000-01-01

Radioactive wastes generated at various stages in the nuclear fuel cycle vary considerably in relation to volume, physical and chemical properties, and radioactivity. The management of these wastes prior to disposal has to be adapted to these conditions, which calls for suitable characterization and minimization, collection, interim storage and conditioning of the wastes. Experience gained over decades shows that current predisposal waste management practices are well advanced. Whereas problems related to inadequate waste management practices in the past have been encountered at several sites and need ongoing remedial actions, modern practices have good safety records. Considerable development and improvement of waste management practices have been achieved and as a consequence of delays in implementing repositories in several countries they remain important tasks. Decommissioning and dismantling of nuclear facilities also have to be taken into account. In most cases, these activities can be performed using existing technical means and practices. No significant safety concerns have been found for the long term storage of spent fuel and vitrified waste. Dry storage has reached technical maturity and appears to be attractive, especially for aged fuel. It has, however, to be stressed that long term storage is not the ultimate solution. Continued efforts to implement repositories are mandatory in order to maintain a credible and responsible strategy for waste management. (author)

Ideological Considerations in Official Dubbing in Iran

Directory of Open Access Journals (Sweden)

Masood Khoshsaligheh

2016-02-01

Full Text Available In our globalizing world, audiovisual products are understandably considered tools that advertise their original language and culture. Most societies do not stand any interference from the outside, especially if it considerably opposes the socio-cultural norms. Translation is a practice of cross-cultural communication which most often complies with the socio-cultural guidelines and norms of the recipient society. However, translated products might face resistance as they can be regarded threatening and hostile by the ruling gatekeepers. Given the dramatic disparities between most languages and cultures, translators are not the only decision-makers and other agents have pivotal roles in the process of adapting the translated product to the dominant conventions and socio-cultural norms. This paper aims at shedding some light on the role which agents play in the process of dubbing, both for public access national television and for private home distribution. The study explores the effects of preliminary and operational norms, and cultural appropriation conducted at both textual and visual levels through a method including interview data and textual analysis. The results show that foreign movies dubbed into Persian in the religious context of the contemporary Iran are strictly controlled both before the process of dubbing and during and after the process of dubbing due to a number of socio-cultural, political, and ideological considerations.

Bridging Body and Mind: Considerations for Trauma-Informed Yoga.

Science.gov (United States)

Justice, Lauren; Brems, Christiane; Ehlers, Karrie

2018-02-08

Individuals who suffer from trauma-related symptoms are a unique population that could benefit from the mind-body practice of yoga-or have their symptoms reactivated by it, depending on the type of yoga. Trauma-informed yoga (TIY), that is, yoga adapted to the unique needs of individuals working to overcome trauma, may ameliorate symptoms by creating a safe, tailored practice for students to learn how to respond, rather than react, to symptoms and circumstances. Yoga not thus adapted, on the other hand, may increase reactivity and activate symptoms such as hyperarousal or dissociation. This article reports on expert input about adapting yoga for individuals with trauma, with special considerations for military populations. Eleven experts, recruited based on literature review and referrals, were interviewed in person or via telephone and asked seven questions about trauma-informed yoga. Verbatim transcripts were subjected to open-coding thematic analysis and a priori themes. Findings revealed that TIY needs to emphasize beneficial practices (e.g., diaphragmatic breath and restorative postures), consider contraindications (e.g., avoiding sequences that overly engage the sympathetic nervous system), adapt to limitations and challenges for teaching in unconventional settings (e.g., prisons, VA hospitals), and provide specialized training and preparation (e.g., specialized TIY certifications, self-care of instructors/therapists, adaptions for student needs). TIY for veterans must additionally consider gender- and culture-related barriers, differing relationships to pain and injury, and medication as a barrier to practice.

High energy physics at Brookhaven National Lab

International Nuclear Information System (INIS)

Samios, N.P.

1982-01-01

The AGS is supporting an exciting, vibrant, and vital program. There are at present two modes of operation, Fast Extracted Beam (FEB) with a 1.4 second repetition rate and Slow Extracted Beam (SEB) with a 2 second repetition rate. The average intensity is 8 x 10/sup 12/ protons per pulse with peaks at 10/sup 13/ ppp. The FEB mode is mainly utilized for neutrino physics involving large detectors, 100-200 tons, placed at varying distances from the target, 300 meters and 1 kilometer. In the slow mode there is a one second flat top during which the beam emerges uniformly in time and it is split into four target stations: A, B, C, and D. These four are simultaneously illuminated and the fractions on each can be varied. A listing of the types of approved experiments is presented with their appropriate beam locations. The experimental program ran for 22 weeks. Over 200 users practice their trade at the AGS and the program is sufficiently rich that there is a reasonable chance that one or more experimenters will uncover new results that will change the way we think about particle physics

Behavioral Medicine and University Departments of Family Practice

OpenAIRE

Grantham, Peter

1983-01-01

Behavioral medicine brings knowledge and skills from the social sciences to the practice of medicine. Modifying behavior which causes a health problem, disease prevention and health promotion, improving the relationship between patients and health professionals, understanding cultural and ethical issues, and the effect of illness on behavior are all aspects of behavioral medicine. Such `whole person' medicine fits well into family practice. However, careful consideration of the risks, challen...

Online Finding Aids: Are They Practical?

Science.gov (United States)

Hostetter, Christina J.

2004-01-01

This article explores the uses, practicality, and problems involved in creating online finding aids by state-funded university archivists across the nation. It examines various aspects of online finding aids such as financial considerations, its importance as a research tool, timelines, demographics, and use. The more technical side is also…

[Digital radiography in young children. Considerations based on experiences in practice].

Science.gov (United States)

Berkhout, W E R; Mileman, P A; Weerheijm, K L

2004-10-01

In dentistry, digital radiology techniques, such as a charge-coupled device and a storage phosphor plate, are gaining popularity. It was the objective of this study to assess the importance of the advantages and disadvantages of digital radiology techniques for bitewing radiography in young children, when compared to conventional film. A group of dentists received a questionnaire regarding their experiences with digital radiology techniques or conventional films among young children. Using the Simple Multi-Attributive Rating Technique (SMART) a final weighted score was calculated for the charge-coupled device, the phosphor plate, and conventional film. The scores were 7.40, 7.38, and 6.98 respectively. The differences were not statistically significant (p > 0.47). It could be concluded that, on the basis of experiences in practice, there are no statistically significant preferences for the use of digital radioogy techniques for bitewing radiography in young children.

46 CFR 114.550 - Special consideration.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Special consideration. 114.550 Section 114.550 Shipping... consideration. In applying the provisions of this subchapter, the OCMI may give special consideration to... vessel operates must approve any special consideration granted to the vessel. ...

Risk management in clinical practice. Part 5. Ethical considerations for dental enhancement procedures.

Science.gov (United States)

Ahmad, I

2010-09-11

After the demise of the Industrial Age, we currently live in an 'Information Age' fuelled mainly by the Internet, with an ever-increasing medically and dentally literate population. The media has played its role by reporting scientific advances, as well as securitising medical and dental practices. Reality television such as 'Extreme makeovers' has also raised public awareness of body enhancements, with a greater number of people seeking such procedures. To satiate this growing demand, the dental industry has flourished by introducing novel cosmetic products such as bleaching kits, tooth coloured filling materials and a variety of dental ceramics. In addition, one only has to browse through a dental journal to notice innumerable courses and lectures on techniques for providing cosmetic dentistry. The incessant public interest, combined with unrelenting marketing by companies is gradually shifting the balance of dental care from a healing to an enhancement profession. The purpose of this article is to endeavour to answer questions such as, What is aesthetic or cosmetic dentistry? Why do patients seek cosmetic dentistry? Are enhancement procedures a part of dental practice? What, if any, ethical guidelines and constraints apply to elective enhancement procedures? What is the role of the dentist in providing or encouraging this type of 'therapy'? What treatment modalities are available for aesthetic dental treatment?

Discrete modeling considerations in multiphase fluid dynamics

International Nuclear Information System (INIS)

Ransom, V.H.; Ramshaw, J.D.

1988-01-01

The modeling of multiphase flows play a fundamental role in light water reactor safety. The main ingredients in our discrete modeling Weltanschauung are the following considerations: (1) Any physical model must be cast into discrete form for a digital computer. (2) The usual approach of formulating models in differential form and then discretizing them is potentially hazardous. It may be preferable to formulate the model in discrete terms from the outset. (3) Computer time and storage constraints limit the resolution that can be employed in practical calculations. These limits effectively define the physical phenomena, length scales, and time scales which cannot be directly represented in the calculation and therefore must be modeled. This information should be injected into the model formulation process at an early stage. (4) Practical resolution limits are generally so coarse that traditional convergence and truncation-error analyses become irrelevant. (5) A discrete model constitutes a reduced description of a physical system, from which fine-scale details are eliminated. This elimination creates a statistical closure problem. Methods from statistical physics may therefore be useful in the formulation of discrete models. In the present paper we elaborate on these themes and illustrate them with simple examples. 48 refs

32 CFR 643.53 - Consideration.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Consideration. 643.53 Section 643.53 National... Leases § 643.53 Consideration. (a) Unless otherwise authorized by this regulation or directed by the SA, the consideration for a lease of real estate will be the appraised fair market rental value. However...

28 CFR 51.34 - Expedited consideration.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Expedited consideration. 51.34 Section 51... consideration. (a) When a submitting authority is required under State law or local ordinance or otherwise finds... the submission be given expedited consideration. The submission should explain why such consideration...

Considerations on the assessment of economic benefits of industrial tracer application

International Nuclear Information System (INIS)

Guizerix, J.; Margrita, R.

1990-01-01

The benefit of a particular tracer study which can always theoretically be derived is practically very difficult to assess for decision-making which is more often based on rough estimates of it. Other criteria, as safety, environmental protection, 'social benefit', may replace the purely economic considerations. The economic benefits of industrial tracer applications can clearly be perceived through the commercial success of businesses offering tracer services, which implies that all factors involved in the law of supply and demand have (tacitly or explictly) been accounted. (orig.) [de

General Considerations on Leadership in the Hospitality Industry. Conceptual Analysis and Practical Studies

OpenAIRE

Andreia ISPAS

2010-01-01

Leadership in the hospitality industry is still an open research field especially in describing the effects of leadership style on hotel employees. The purpose of the paper is to present and analyze the following concepts: leadership and leadership style, hospitality industry; the practical aspects of leadership in the hospitality industry and to identify relevant studies regarding the importance of leadership styles applied in this industry. The research methodology consists of analyzing the...

32 CFR 643.74 - Consideration.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Consideration. 643.74 Section 643.74 National... Licenses § 643.74 Consideration. When a license is granted under the authority of an easement or leasing statute, the same rules will apply in regard to consideration as is applicable to the granting of an...

Attending physician work hours: ethical considerations and the last doctor standing.

Science.gov (United States)

Mercurio, Mark R; Peterec, Steven M

2009-08-01

Based at least in part on concerns for patient safety and evidence that long shifts are associated with an increased risk of physician error, residents' and fellows' work hours have been strictly limited for the past several years. Little attention has been paid, however, to excessive attending physician shift duration, although there seems to be no reason to assume that this common practice poses any less risk to patients. Potential justifications for allowing attending physicians to work without hourly limits include physician autonomy, workforce shortages in certain communities or subspecialties, continuity of care, and financial considerations. None of these clearly justify the apparent increased risk to patients, with the exception in some settings of workforce shortage. In many hospital settings, the practice of allowing attending physicians to work with no limit on shift duration could pose an unnecessary risk to patients.

Lyme Disease: Emergency Department Considerations.

Science.gov (United States)

Applegren, Nathan D; Kraus, Chadd K

2017-06-01

Lyme disease (LD) is the most common vector-borne illness in North America. Reported cases of LD have increased from approximately 10,000 cases annually in 1991 to >25,000 cases in 2014. Greater recognition, enhanced surveillance, and public education have contributed to the increased prevalence, as have geographic expansion and the number of infected ticks. Cases are reported primarily in the Northeastern United States, Wisconsin, and Minnesota, with children having the highest incidence of LD among all age groups. The increased incidence and prevalence of LD in the United States makes it increasingly more common for patients to present to the emergency department (ED) for tick bites and LD-related chief complaints, such as the characteristic erythema migrans skin manifestation. We sought to review the etiology of LD, describe its clinical presentations and sequela, and provide a practical classification and approach to ED management of patients with LD-related presentations. In this review, ED considerations for LD are presented and clinical presentations and management of the disease at different stages is discussed. Delayed sequelae that have significant morbidity, including Lyme carditis and Lyme neuroborreliosis, are discussed. Diagnostic tests and management are described in detail. The increasing prevalence and growing geographic reach of Lyme disease makes it critically important for emergency physicians to consider the diagnosis in patients presenting with symptoms suggestive of LD and to initiate appropriate treatment to minimize the potential of delayed sequelae. Special consideration should be made for the epidemiology of LD and a high clinical suspicion should be present for patients in endemic areas or with known exposures to ticks. Emergency physicians can play a critical role in the recognition, diagnosis, and treatment of LD. Copyright © 2017 Elsevier Inc. All rights reserved.

Ethical considerations in stem cell research on neurologic and orthopedic conditions.

Science.gov (United States)

Banja, John Dennis

2015-04-01

The range and gravity of ethical considerations in stem cell research are remarkable and, quite possibly, unprecedented. From the point of securing stem cells for implantation, through the translational and first-in-humans process, and then proceeding through clinical trials culminating in product or service line launch, the entire research trajectory is replete with risk, uncertainty, and problems overweighing foreseeable harms against hoped-for benefits. This article offers an overview of some of the most salient ethical challenges of stem cell research, including ones involving moral status, the intersection of research risks and informed consent processes, methodologic considerations in early phase 1 trials, the temptation to exaggerate the benefits of research discoveries, managing conflicts of interest, and the ethical obligation to conduct various monitoring practices throughout a trial, which could last years. The article will conclude with a glimpse into the future of these technologies wherein the need for ethical scrutiny will likely not diminish. Copyright © 2015. Published by Elsevier Inc.

Criteria for the use of monoclonal antibodies, legislation and ethical considerations

International Nuclear Information System (INIS)

Cox, P.H.

1993-01-01

The criteria governing the in vivo use of monoclonal antibodies in humans are based upon a number of legal requirements with respect to radiation hygiene, pharmaceutical legislation, radiopharmaceutical legislation and regulations with respect to products arising from biotechnology. This in itself has led to a complicated situation which has undoubtedly restricted the development of valuable diagnostic and potential therapeutic agents. From the ethical point of view there are also important considerations, firstly with respect to the methods of producing antibodies, which has resulted in the discontinuation of the raising of antibodies in murine ascites, and secondly in consideration of the ethics of administering labelled antibodies to healthy volunteers and to patients who may not necessarily benefit personally from the procedure. These factors must be evaluated in the light of the EEC document 'Good clinical practice for trials in medicinal products in the European Community from the CPMP working party on Efficacy of Medicinal Products'. (author)