Optimization of the BNCT filter
The Czech Boron Neutron Capture Therapy (BNCT) facility works by an epithermal neutron beam installed at the LVR-15 reactor at Rez near Prague. Several configurations of moderating and shielding materials have been designed in order to ensure appropriate parameters of the beam. The beam filter consists of cylindrical layers of Al, AlF3 and Ti. To decrease the gamma two layers of Pb are implemented. The filter geometry and composition has been optimized with the aim to increase the epithermal neutron fluence rate and decrease the fast neutron dose rate using the MCNP-4B Monte Carlo code with the DLC-189 library. Suitable patterns of the reactor core were also studied especially in regard to a possible installation of fuel units close to the filter input. Results of calculations show that the optimized variant of the reactor core is able to increase the intensity of the fast neutron source incident to the filter by a factor of 2.0. An experimental verification of the beam parameters was performed using different measurement techniques. The neutron energy spectrum was measured with a set of activation foils, by a Bonner spheres spectrometer and a fast neutron spectrometer with a stilbene crystal. The fast neutron kerma rate was calculated from the spectral measurement. Al-P TLD were used to measure the photon absorbed dose. The beam parameters were measured at 10 MW and were found as follows: the epithermal neutron fluence rate (an energy range from 1 eV to 10 keV) of 9.29 x 1012 m-2 s-1, the fast neutron kerma rate in tissue of 2.63 Gy h-1 and the incident gamma dose rate in tissue of 29 Gy h-1. (author)
Design of a BNCT facility at HANARO
Based on the feasibility study of the BNCT at HANARO, it was confirmed that only thermal BNCT is possible at the IR beam tube if appropriate filtering system be installed. Medical doctors in Korea Cancer Center Hospital agreed that the thermal BNCT facility would be worthwhile for the BNCT technology development in Korea as well as superficial cancer treatment. For the thermal BNCT to be effective, the thermal neutron flux should be high enough for patient treatment during relatively short time and also the fast neutron and gamma-ray fluxes should be as low as possible. In this point of view, the following design requirements are set up: 1) thermal neutron flux at the irradiation position should be higher than 3x109 n/cm2-sec, 2) ratio of the fast neutrons and gamma-rays to the thermal neutrons should be minimized, and 3) patient treatment should be possible without interrupt to the reactor operation. To minimize the fast neutrons and gamma-rays with the required thermal neutrons at the irradiation position, a radiation filter consisting of single crystals of silicon and bismuth at liquid nitrogen temperature is designed. For the shielding purpose around the irradiation position, polyethylene, lead, LiF, etc., are appropriately arranged around the radiation filter. A water shutter in front of the radiation filter is adopted so as to avoid interrupt to the reactor operation. At present, detail design of the radiation filter is ongoing. Cooling capabilities of the filter will be tested through a mockup experiment. Dose rate distributions around the radiation filter and a prompt gamma-ray activation analysis system for the analyses of boron content in the biological samples are under design. The construction of this facility will be started from next year if it is permitted from the regulatory body this year. Some other future works exist and are described in the paper. (author)
Design of a BNCT facility at HANARO
Based on the feasibility study of the BNCT at HANARO, it was confirmed that only thermal BNCT is possible at the IR beam tube if appropriate filtering system be installed. Medical doctors in Korea Cancer Center Hospital agreed that the thermal BNCT facility would be worthwhile for the BNCT technology development in Korea as well as superficial cancer treatment. For the thermal BNCT to be effective, the thermal neutron flux should be high enough for patient treatment during relatively short time and also the fast neutron and gamma-ray fluxes should be as low as possible to avoid high dose on the patient during treatment. In this point of view, the following design requirements are set up; 1) thermal neutron flux at the irradiation position should be higher than 2 X 109 n/cm2 . sec, 2) ration of the fast neutrons and gamma-rays to the thermal neutrons should be minimized, and 3) patient treatment should be possible during reactor operation. To minimize the fast neutrons and gamma-rays with the required thermal neutrons at the irradiation position, a radiation filter consisting of single crystals of silicon and bismuth at liquid nitrogen temperature is design d. For the shielding purpose around the irradiation position, polyethylene, lead, LiF, etc., are appropriately arranged around the radiation filter. A water shutter in front of the radiation filter is adopted so as to avoid interrupt to the reactor operation. While the shutter is filled in water during on power, the radiation level in the irradiation room is sufficiently low for the preparation work for patient irradiation including temporary surgery. At present, detail design of the radiation filter is ongoing. cooling capabilities of the filter will be tested through a mockup experiment. Dose rate distributions around the radiation filter are under analysis for the configuration of the irradiation room. A prompt gamma-ray activation analysis system for the analyses of boron content in the biological samples, is
Application of multiprocessor calculations in IRT BNCT channel design
The Research Reactor IRT (IRT) Sofia, of the Institute for Nuclear Research and Nuclear Energy of the Bulgarian Academy of Sciences (INRNE) is in a process of reconstruction. The technical project includes an arrangement of Boron Neutron Capture Therapy (NCT) facility. The development of BNCT for head and neck cancer, and liver cancer is one of the main tasks in the Program for sustainable application of the reactor. The physical design of the BNCT channel proved itself to be a heavy demanding task in terms of investigation of the filter/moderator materials' physical behaviour that will be suitable for the IRT reactor's specific conditions. The IRT-Sofia NCT beam tube optimization study and the followed investigations of different filter/moderator materials and in-phantom biological doses would require a big number of sophisticated 3-dimensional calculations. The computational time for performing these calculations with the current computer setup would be unacceptably great. That is why a new version of the MCNP code with extensive capabilities for multiprocessor calculations was introduced. The compatibility with the results obtained in calculations with previous version is shown. The inheritance between the calculations sequence is justified. The gain in speed is demonstrated. (authors)
Spatial and spectral characteristics of a compact system neutron beam designed for BNCT facility
The development of suitable neutron sources and neutron beam is critical to the success of Boron Neutron Capture Therapy (BNCT). In this work a compact system designed for BNCT is presented. The system consists of 252Cf fission neutron source and a moderator/reflector/filter/shield assembly. The moderator/reflector/filter arrangement has been optimized to maximize the epithermal neutron component which is useful for BNCT treatment of deep seated tumors with the suitably low level of beam contamination. The MCMP5 code has been used to calculate the different components of neutrons, secondary gamma rays originating from 252Cf source and the primary gamma rays emitted directly by this source at the exit face of the compact system. The fluence rate distributions of such particles were also computed along the central axis of a human head phantom
Spatial and spectral characteristics of a compact system neutron beam designed for BNCT facility
Ghassoun, J. [EPRA, Departement de Physique, Faculte des Sciences Semlalia, B.P. 2390, 40000 Marrakech (Morocco)], E-mail: ghassoun@ucam.ac.ma; Chkillou, B.; Jehouani, A. [EPRA, Departement de Physique, Faculte des Sciences Semlalia, B.P. 2390, 40000 Marrakech (Morocco)
2009-04-15
The development of suitable neutron sources and neutron beam is critical to the success of Boron Neutron Capture Therapy (BNCT). In this work a compact system designed for BNCT is presented. The system consists of {sup 252}Cf fission neutron source and a moderator/reflector/filter/shield assembly. The moderator/reflector/filter arrangement has been optimized to maximize the epithermal neutron component which is useful for BNCT treatment of deep seated tumors with the suitably low level of beam contamination. The MCMP5 code has been used to calculate the different components of neutrons, secondary gamma rays originating from {sup 252}Cf source and the primary gamma rays emitted directly by this source at the exit face of the compact system. The fluence rate distributions of such particles were also computed along the central axis of a human head phantom.
Spatial and spectral characteristics of a compact system neutron beam designed for BNCT facility.
Ghassoun, J; Chkillou, B; Jehouani, A
2009-04-01
The development of suitable neutron sources and neutron beam is critical to the success of Boron Neutron Capture Therapy (BNCT). In this work a compact system designed for BNCT is presented. The system consists of (252)Cf fission neutron source and a moderator/reflector/filter/shield assembly. The moderator/reflector/filter arrangement has been optimized to maximize the epithermal neutron component which is useful for BNCT treatment of deep seated tumors with the suitably low level of beam contamination. The MCMP5 code has been used to calculate the different components of neutrons, secondary gamma rays originating from (252)Cf source and the primary gamma rays emitted directly by this source at the exit face of the compact system. The fluence rate distributions of such particles were also computed along the central axis of a human head phantom. PMID:19168369
Following the formation in 1987, of both the European Collaboration group on Boron Neutron Capture Therapy (BNCT) and the Petten BNCT group, steps were taken to design and implement an epithermal neutron beam for BNCT applications at the High Flux Reactor (HFR) at Petten. The installation would serve as a European facility, while once the modality of BNCT is proven would be the pathfinder for implementation of BNCT at other European nuclear sites. Due to its favorable nuclear and geometric characteristics, the beam tube HB11 was chosen as the candidate beam tube for BNCT applications. To reconfigure the beam tube to produce the required epithermal neutrons, it was first necessary to remove the existing mirror system and then to install the appropriate filter materials. Due to the fixed operating schedule of the HFR, with only one long shut-down period per year during the summer weeks for maintenance and upgrading actions, installation of the new facility was planned for the summer stop period in 1990
A multi-dimensional procedure for BNCT filter optimization
An initial version of an optimization code utilizing two-dimensional radiation transport methods has been completed. This code is capable of predicting material compositions of a beam tube-filter geometry which can be used in a boron neutron capture therapy treatment facility to improve the ratio of the average radiation dose in a brain tumor to that in the healthy tissue surrounding the tumor. The optimization algorithm employed by the code is very straightforward. After an estimate of the gradient of the dose ratio with respect to the nuclide densities in the beam tube-filter geometry is obtained, changes in the nuclide densities are made based on: (1) the magnitude and sign of the components of the dose ratio gradient, (2) the magnitude of the nuclide densities, (3) the upper and lower bound of each nuclide density, and (4) the linear constraint that the sum of the nuclide density fractions in each material zone be less than or equal to 1.0. A local optimal solution is assumed to be found when one of the following conditions is satisfied in every material zone: (1) the maximum positive component of the gradient corresponds to a nuclide at its maximum density and the sum of the density fractions equals 1.0 or, and (2) the positive and negative components of the gradient correspond to nuclides densities at their upper and lower bounds, respectively, and the remaining components of the gradient are sufficiently small. The optimization procedure has been applied to a beam tube-filter geometry coupled to a simple tumor-patient head model and an improvement of 50% in the dose ratio was obtained
Epithermal BNCT neutron beam design for a TRIGA II reactor
In Finland a collaborative effort by Helsinki University Central Hospital, MAP Medical Technologies Inc. and VTT Reactor Laboratory has started aiming at BNCT of glioma patients. For this the capabilities of the FiR-1 TRIGA II 250 kW research reactor have been evaluated. The FiR-1 is located in the middle of the Otaniemi campus eight kilometers from the center of Helsinki and four kilometers from the Central Hospital. The power of the reactor was increased in 1965 to 250 kW and the instrumentation modernised in 1981. It is a pool reactor with graphite reflector and a core loading of 3 kg 20w% 235U in the special TRIGA uranium-zirconium hydride fuel (8-12 w% U, 91% Zr, 1% H). The advantages of using a TRIGA reactor for BNCT have already been pointed out earlier by Whittemore and have been verified in practice by the thermal neutron treatment work done at the Musashi 100 kW reactor. The advantages include a wide core face area and a wide spatial angle covered by the thermal-epithermal column system, large flux-per-Watt feature and inherent safety of the TRIGA fuel. Because of its wider applicability and less stringent requirements for clinical operation conditions, an epithermal neutron beam has been selected as the design goal. The epithermal flux should be sufficient for glioblastoma patient treatment: 109 epithermal neutrons/cm2/s with low enough fast neutron (-13Gy/epithermal n/cm2) and gamma contamination
Neutron collimator design of neutron radiography based on the BNCT facility
Yang, XP.; Yu, BX; Li, YG; Peng, D; Lu, J.; Zhang, GL.; Zhao, H.; Zhang, AW.; Li, CY.; Liu, WJ; Hu, T.; Lv, JG.
2013-01-01
For the research of CCD neutron radiography, a neutron collimator was designed based on the exit of thermal neutron of the Boron Neutron Capture Therapy (BNCT) reactor. Based on the Geant4 simulations, the preliminary choice of the size of the collimator was determined. The materials were selected according to the literature data. Then, a collimator was constructed and tested on site. The results of experiment and simulation show that the thermal neutron flux at the end of theneutron collimat...
INEL BNCT Research Program annual report 1994
This report is a summary of the progress and research produced for the Idaho National Engineering Laboratory (INEL) Boron Neutron Capture Therapy (BNCT) Research Program for calendar year 1994. Contributions from the principal investigators about their individual projects are included, specifically, chemistry (pituitary tumor studies, boron drug development including liposomes, lipoproteins, and carboranylalanine derivatives), pharmacology (murine screenings, toxicity testing, ICP-AES analysis of biological samples), physics (treatment planning software, neutron beam and filter design, neutron beam measurement dosimetry), and radiation biology (small and large animal models tissue studies and efficacy studies). Information on the potential toxicity of BSH and BPA is presented and results of 21 spontaneous tumor bearing dogs that have been treated with BNCT at Brookhaven National Laboratory (BNL) are discussed. Several boron carrying drugs exhibiting good tumor uptake are described. Significant progress in the potential of treating pituitary tumors is presented. Highlights from the First International Workshop on Accelerator-Based Neutron Sources for BNCT are included
BNCT facility development in HANARO
An irradiation facility for boron neutron capture therapy (BNCT) was developed using one of the typical tangential beam tubes in HANARO. Thermal neutron was chosen because of the impossibility of sufficient epithermal neutrons for BNCT at the exit of the beam tube. The facility is designed not only for BNCT study but also for dynamic neutron radiography (DNR) and other experiments requiring pure thermal neutrons. Silicon and bismuth single crystals cooled by liquid nitrogen are selected to filter out fast neutrons and γ-rays and to penetrate the thermal neutrons as much as possible. A water shutter is installed in front of the radiation filter to keep the radiation level low in the irradiation room while it is filled with water. A prompt gamma neutron activation analysis (PGNAA) system was also developed to measure the boron concentration quickly from patient's blood samples. A spare neutron beam from a dedicated beam instrument was diffracted upward using pyrolytic graphite to obtain almost pure thermal neutrons at the target position. (author)
This work reports on the characterisation of a neutron beam shaping assembly (BSA) prototype and on the preliminary modelling of a treatment room for BNCT within the framework of a research programme for the development and construction of an accelerator-based BNCT irradiation facility in Buenos Aires, Argentina. The BSA prototype constructed has been characterised by means of MCNP simulations as well as a set of experimental measurements performed at the Tandar accelerator at the National Atomic Energy Commission of Argentina. - Highlights: ► Characterisation of a neutron beam shaping assembly for accelerator-based BNCT. ► Measurements: total and epi-cadmium neutron fluxes and beam homogeneity. ► Calculations: Monte Carlo simulations with the MCNP code. ► Measured and calculated figure-of-merit parameters in agreement with those of IAEA. ► Initial MCNP dose calculations for a treatment room to define future design actions.
A cavity filter was developed for the SSRF 0-mode beam feedback. The filter is used to pick up the 500 MHz signal from the storage ring beam. The Superfish was used to simulate the model of the cavity bandpass filter. The design method, parameters of the filter and results of beam measurements are described in this paper. (authors)
Neutron collimator design of neutron radiography based on the BNCT facility
Yang, XP; Li, YG; Peng, D; Lu, J; Zhang, GL; Zhao, H; Zhang, AW; Li, CY; Liu, WJ; Hu, T; Lv, JG
2013-01-01
For the research of CCD neutron radiography, a neutron collimator was designed based on the exit of thermal neutron of the Boron Neutron Capture Therapy (BNCT) reactor. Based on the Geant4 simulations, the preliminary choice of the size of the collimator was determined. The materials were selected according to the literature data. Then, a collimator was constructed and tested on site. The results of experiment and simulation show that the thermal neutron flux at the end of theneutron collimator is greater than 10^6 n/cm^2/s, the maximum collimation ratio (L/D) is 58, the Cd-ratio(Mn) is 160 and the diameter of collimator end is 10 cm. This neutron collimator is considered to be applicable for neutron radiography.
Neutron collimator design of neutron radiography based on the BNCT facility
For the research of CCD neutron radiography, a neutron collimator was designed based on the exit of thermal neutron of the Boron Neutron Capture Therapy (BNCT) reactor. Based on the Geant4 simulations, the preliminary choice of the size of the collimator was determined. The materials were selected according to the literature data. Then, a collimator was constructed and tested on site. The results of experiment and simulation show that the thermal neutron flux at the end of the neutron collimator is greater than 1.0×106 n/cm2/s, the maximum collimation ratio (L/D) is 58, the Cd-ratio(Mn) is 160 and the diameter of collimator end is 10 cm. This neutron collimator is considered to be applicable for neutron radiography. (authors)
Highlights: ► The possibility of using natural uranium as a neutron multiplier for D–T neutron generator is examined. ► To optimize output neutron beam, a moderator/filter/reflector arrangement was designed. ► The MCNP4C code has been used for BSA optimization and other simulations. ► The results show that using this system the BNCT in-air recommended parameters are met. - Abstract: Extensive research has recently been carried out for the development of high-energy D–T neutron generators as neutron sources for BNCT. The energy of these high-energy neutrons must be reduced by designing a Beam Shaping Assembly (BSA) to make them usable for BNCT. However, the neutron flux decreases drastically as neutrons pass through different materials of BSA. Therefore, it is very important to find ways to treat the neutrons economically. In this paper the possibility of using natural uranium as a neutron multiplier is investigated in order to increase the number of neutrons emitted from D–T neutron generator. According to the simulations and performed calculations, a sphere containing natural uranium as neutron multiplier was used to increase the number of neutrons generated by the D–T neutron generator. The energy of fast neutrons that are generated by D–T fusion reaction and amplified by neutron multiplier system is decreased using proper materials as moderators and fast neutron filters in BSA. The gamma rays which are generated as a result of neutron interaction with moderators are removed from neutron spectrum using bismuth as the gamma filter. Also, a thermal neutron absorber omits undesired low-energy neutrons which lead to a high radiation dose for the skin and soft tissues. The results show that passing neutrons through such a BSA causes the establishment of free beam parameters yet the reduction of the output beam intensity is unavoidable. The neutron spectrum related to our BSA has a proper epithermal flux and the fast and thermal neutron fluxes are
IRT-Sofia BNCT beam tube optimization study
An optimization study of IRT-Sofia BNCT beam tube is presented. In the study we used the MIT/FCB experience. The enlarging of filter/moderator cross section dimensions and the decreasing of collimator length within the limits of the IRT-Sofia reactor design were analyzed. The influence of beam and reactor core axes non-coincidence on the beam properties was also evaluated. The irradiation resistance of polytetrafluoroethylene (Teflon®) was also evaluated. The results provide information for making decisions on the IRT-Sofia BNCT beam construction.
IRT-Sofia BNCT beam tube optimization study
Belousov, S., E-mail: belousov@inrne.bas.bg [Institute for Nuclear Research and Nuclear Energy (INRNE) of the Bulgarian Academy of Sciences, Tsarigradsko 72, Sofia (Bulgaria); Mitev, M.; Ilieva, K. [Institute for Nuclear Research and Nuclear Energy (INRNE) of the Bulgarian Academy of Sciences, Tsarigradsko 72, Sofia (Bulgaria); Riley, K. [Radiation Monitoring Devices, Watertown, MA (United States); Harling, O. [Nuclear Science and Engineering Department, Massachusetts Institute of Technology, Cambridge, MA (United States)
2011-12-15
An optimization study of IRT-Sofia BNCT beam tube is presented. In the study we used the MIT/FCB experience. The enlarging of filter/moderator cross section dimensions and the decreasing of collimator length within the limits of the IRT-Sofia reactor design were analyzed. The influence of beam and reactor core axes non-coincidence on the beam properties was also evaluated. The irradiation resistance of polytetrafluoroethylene (Teflon{sup Registered-Sign }) was also evaluated. The results provide information for making decisions on the IRT-Sofia BNCT beam construction.
Simplified design of filter circuits
Lenk, John
1999-01-01
Simplified Design of Filter Circuits, the eighth book in this popular series, is a step-by-step guide to designing filters using off-the-shelf ICs. The book starts with the basic operating principles of filters and common applications, then moves on to describe how to design circuits by using and modifying chips available on the market today. Lenk's emphasis is on practical, simplified approaches to solving design problems.Contains practical designs using off-the-shelf ICsStraightforward, no-nonsense approachHighly illustrated with manufacturer's data sheets
Simulation of the BNCT of Brain Tumors Using MCNP Code: Beam Designing and Dose Evaluation
BNCT is an effective method to destroy brain tumoral cells while sparing the healthy tissues. The recommended flux for epithermal neutrons is 109 n/cm2s, which has the most effectiveness on deep-seated tumors. In this paper, it is indicated that using D-T neutron source and optimizing of Beam Shaping Assembly leads to treating brain tumors in a reasonable time where all International Atomic Energy Agency recommended criteria are met. The proposed Beam Shaping Assembly based on a D-T neutron generator consists of a neutron multiplier system, moderators, reflector, and collimator. The simulated Snyder head phantom is used to evaluate dose profiles in tissues due to the irradiation of designed beam. Monte Carlo Code, MCNP-4C, was used in order to perform these calculations. The neutron beam associated with the designed and optimized Beam Shaping Assembly has an adequate epithermal flux at the beam port and neutron and gamma contaminations are removed as much as possible. Moreover, it was showed that increasing J/Φ, as a measure of beam directionality, leads to improvement of beam performance and survival of healthy tissues surrounding the tumor. According to the simulation results, the proposed system based on D-T neutron source, which is suitable for in-hospital installations, satisfies all in-air parameters. Moreover, depth-dose curves investigate proper performance of designed beam in tissues. The results are comparable with the performances of other facilities.
Filter Bank Design for Subband Adaptive Filtering
Haan, Jan Mark de
2001-01-01
Adaptive filtering is an important subject in the field of signal processing and has numerous applications in fields such as speech processing and communications. Examples in speech processing include speech enhancement, echo- and interference- cancellation, and speech coding. Subband filter banks have been introduced in the area of adaptive filtering in order to improve the performance of time domain adaptive filters. The main improvements are faster convergence speed and the reduction of co...
Conceptual design of epithermal neutron beam for BNCT in the thermalizing column of TRIGA reactor
The Monte Carlo feasibility study of development of the epithermal neutron beam for BNCT clinical trials in thermalising column (TC) of TRIGA reactor is presented. The investigation of the possible use of fission converter as well as the set-up of TRIGA reactor core is performed. The optimization of the irradiation facility components is carried out and the configuration with the most favorable cost/performance ratio is proposed. The results prove, that a BNCT irradiation facility with performances, comparable to existing beams throughout the world, could be installed in TC/DC of the TRIGA reactor, quite suitable for the clinical treatments of human patients.(author)
INEL BNCT Research Program annual report 1994
Venhuizen, J.R. [ed.
1995-11-01
This report is a summary of the progress and research produced for the Idaho National Engineering Laboratory (INEL) Boron Neutron Capture Therapy (BNCT) Research Program for calendar year 1994. Contributions from the principal investigators about their individual projects are included, specifically, chemistry (pituitary tumor studies, boron drug development including liposomes, lipoproteins, and carboranylalanine derivatives), pharmacology (murine screenings, toxicity testing, ICP-AES analysis of biological samples), physics (treatment planning software, neutron beam and filter design, neutron beam measurement dosimetry), and radiation biology (small and large animal models tissue studies and efficacy studies). Information on the potential toxicity of BSH and BPA is presented and results of 21 spontaneous tumor bearing dogs that have been treated with BNCT at Brookhaven National Laboratory (BNL) are discussed. Several boron carrying drugs exhibiting good tumor uptake are described. Significant progress in the potential of treating pituitary tumors is presented. Highlights from the First International Workshop on Accelerator-Based Neutron Sources for BNCT are included. Selected papers have been indexed separately for inclusion in the Energy Science and Technology Database.
Automated Integrated Analog Filter Design Issues
Karolis Kiela; Romualdas Navickas
2015-01-01
An analysis of modern automated integrated analog circuits design methods and their use in integrated filter design is done. Current modern analog circuits automated tools are based on optimization algorithms and/or new circuit generation methods. Most automated integrated filter design methods are only suited to gmC and switched current filter topologies. Here, an algorithm for an active RC integrated filter design is proposed, that can be used in automated filter designs. The algorithm is t...
Design of epithermal neutron beam for clinical BNCT treatment at Slovenian TRIGA research reactor
The Monte Carlo feasibility study of development of epithermal neutron beam for BNCT clinical trials on Jozef Stefan Institute (JSI) TRIGA reactor is presented. The investigation of the possible use of fission converter for the purpose of enhancement of neutron beam, as well as the set-up of TRIGA reactor core is performed. The optimization of the irradiation facility components is carried out and the configuration with the most favorable cost/performance ratio is proposed. The simulation results prove that a BNCT irradiation facility with performances, comparable to existing beams throughout the world, could be installed in the thermalizing column of the TRIGA reactor, quite suitable for the clinical treatments of human patients. (author)
Design of epithermal neutron beam for clinical BNCT treatment at Slovenian TRIGA research reactor
Maucec, Marko [Jozef Stefan Institute, Reactor Physics Division, Lubljana (Slovenia). E-mail: marko.mauce@ijs.si
1999-07-01
The Monte Carlo feasibility study of development of epithermal neutron beam for BNCT clinical trials on Jozef Stefan Institute (JSI) TRIGA reactor is presented. The investigation of the possible use of fission converter for the purpose of enhancement of neutron beam, as well as the set-up of TRIGA reactor core is performed. The optimization of the irradiation facility components is carried out and the configuration with the most favorable cost/performance ratio is proposed. The simulation results prove that a BNCT irradiation facility with performances, comparable to existing beams throughout the world, could be installed in the thermalizing column of the TRIGA reactor, quite suitable for the clinical treatments of human patients. (author)
Evaluation of D(d,n)3 He reaction neutron source models for BNCT irradiation system design
YAO Ze'en; LUO Peng; Tooru KOBAYASHI; Gerard BENGUA
2007-01-01
A mathematical method was developed to calculatc the yield.energy spectrum and angular distribution of neutrons from D(d,n)3 He(D-D)reaction in a thick deuterium-titanium target for incident deuterons in energies lower than 1.0MeV.The data of energy spectrum and angular distribution wefe applied to set up the neutron source model for the beam-shaping-assembly(BSA)design of Boron-Neutron-Capture-Therapy(BNCT)using MCNP-4C code.Three cases of D-D neutron source corresponding to incident deuteron energy of 1000.400 and 150 kaV were investigated.The neutron beam characteristics were compared with the model of a 2.45 MeV mono-energetic and isotropic neutron source using an example BSA designed for BNCT irradiation.The results show significant differences in the neutron beam characteristics,particularly the fast neutron component and fast neutron dose in air,between the non-isotropic neutron source model and the 2.5 MeV mono-energetic and isotropic neutron source model.
HF filter design and computer simulation
Rhea, Randall W
1994-01-01
A book for engineers who design and build filters of all types, including lumped element, coaxial, helical, dielectric resonator, stripline and microstrip types. A thorough review of classic and modern filter design techniques, containing extensive practical design information of passband characteristics, topologies and transformations, component effects and matching. An excellent text for the design and construction of microstrip filters.
The geometry of reactor core, thermal column, collimator and shielding system for BNCT application of TRIGA MARK II Reactor were simulated with MCNP5 code. Neutron particle lethargy and dose were calculated with MCNPX code. Neutron flux in a sample located at the end of collimator after normalized to measured value (Eid Mahmoud Eid Abdel Munem, 2007) at 1 MW power was 1.06 x 108 n/ cm2/ s. According to IAEA (2001) flux of 1.00 x 109 n/ cm2/ s requires three hours of treatment. Few modifications were needed to get higher flux. (Author)
Theory and design of microwave filters
Hunter, Ian
2000-01-01
This is a thorough, graduate-level text which provides a single source for filter design including basic circuit theory, network synthesis and the design of a variety of microwave filter structures. The aim is to present design theories followed by specific examples with numerical simulations of the designs, with pictures of real devices wherever possible. The book is aimed at designers, engineers and researchers working in microwave electronics who need to design or specify filters.
A model of multiple lung metastases in BDIX rats is under study at CNEA (Argentina) to evaluate the feasibility of BNCT for multiple, non-surgically resectable lung metastases. A practical shielding device that comfortably houses a rat, allowing delivery of a therapeutic, uniform dose in lungs while protecting the body from the neutron beam is presented. Based on the final design obtained by numerical simulations, the shield was constructed, experimentally characterized and recently used in the first in vivo experiment at RA-3. - Highlights: • A practical shielding device that comfortably houses a rat is presented. • The shield allows a uniform and useful dose in the rat thoracic area. • A novel computational dosimetry in animals based on Multicell is presented. • Experimental characterization evidences the good performance of the shield. • An irradiation based on a diffuse lung metastases model in rats was performed
Design of a SPECT tomographic image system for online dosimetry in BNCT
We present here a numerical analysis of a projected tomographic image system for online dose measurements in Boron Neutron Capture Therapy. In 94% of neutron capture reactions in boron, the 7Li ion is emitted in an excited state which decays through a characteristic 478 keV prompt gamma ray. In BNCT a large fraction of this radiation escapes from the patient body. Its detection is thus attractive for a noninvasive boron dose measurement and an online absorbed dose evaluation. For this purpose we have proposed a dedicated SPECT (Single Photon Emission Computed Tomography) imaging system. The proposed system can obtain images of 21x21cm2 divided in 1x1cm2 pixels by measuring 20 projections with 41 bins each, with 8% uncertainties in reconstructed dose. (author)
Filter and Filter Bank Design for Image Texture Recognition
Randen, Trygve
1997-12-31
The relevance of this thesis to energy and environment lies in its application to remote sensing such as for instance sea floor mapping and seismic pattern recognition. The focus is on the design of two-dimensional filters for feature extraction, segmentation, and classification of digital images with textural content. The features are extracted by filtering with a linear filter and estimating the local energy in the filter response. The thesis gives a review covering broadly most previous approaches to texture feature extraction and continues with proposals of some new techniques. 143 refs., 59 figs., 7 tabs.
Active resistance capacitance filter design
Kerwin, W. J.
1970-01-01
Filters, formed by combinations of distributed RC elements with positive-feedback voltage amplifiers, provide transfer functions similar to those the heavier LC filters ordinarily employ. They also provide signal amplification.
Design and construction of electronic filters
The design and construction of very low frequencies electronic filters which will be used for carrying out analysis of pile noise at Mexico's Nuclear Center Triga Mark III Reactor, in order to realize measurements of its parameters is presented. NIM norms and active filters with lineal integrated circuits were used: a. Band pass filter from 10 to 500 hertz, band width 50. b. Low pass filter from 0.001 to 10 hertz in 3 steps. c. Kalman Bucy filter, an analogical simulation of this filter was undertaken, obtained from a mathematical model of a Zero power experimental reactor, with the purpose to establish a control searching. (author)
INEL BNCT Research Program annual report, 1992
Venhuizen, J.R. [ed.
1993-05-01
This report is a summary of the progress and research produced for the Idaho National Engineering Laboratory Boron Neutron Capture Therapy (BNCT) Research Program for calendar year 1992. Contributions from all the principal investigators about their individual projects are included, specifically, chemistry (pituitary tumor targeting compounds, boron drug development including liposomes, lipoproteins, and carboranylalanine derivatives), pharmacology (murine screenings, toxicity testing, inductively coupled plasma-atomic emission spectroscopy (ICP-AES) analysis of biological samples), physics (radiation dosimetry software, neutron beam and filter design, neutron beam measurement dosimetry), and radiation biology (small and large animal models tissue studies and efficacy studies). Information on the potential toxicity of borocaptate sodium and boronophenylalanine is presented, results of 21 spontaneous-tumor-bearing dogs that have been treated with BNCT at the Brookhaven National Laboratory (BNL) Medical Research Reactor (BMRR) are discussed, and predictions for an epithermal-neutron beam at the Georgia Tech Research Reactor (GTRR) are shown. Cellular-level boron detection and localization by secondary ion mass spectrometry, sputter-initiated resonance ionization spectroscopy, low atomization resonance ionization spectroscopy, and alpha track are presented. Boron detection by ICP-AES is discussed in detail. Several boron carrying drugs exhibiting good tumor uptake are described. Significant progress in the potential of treating pituitary tumors with BNCT is presented. Measurement of the epithermal-neutron flux at BNL and comparison to predictions are shown. Calculations comparing the GTRR and BMRR epithermal-neutron beams are also presented. Individual progress reports described herein are separately abstracted and indexed for the database.
INEL BNCT Research Program annual report, 1992
This report is a summary of the progress and research produced for the Idaho National Engineering Laboratory Boron Neutron Capture Therapy (BNCT) Research Program for calendar year 1992. Contributions from all the principal investigators about their individual projects are included, specifically, chemistry (pituitary tumor targeting compounds, boron drug development including liposomes, lipoproteins, and carboranylalanine derivatives), pharmacology (murine screenings, toxicity testing, inductively coupled plasma-atomic emission spectroscopy (ICP-AES) analysis of biological samples), physics (radiation dosimetry software, neutron beam and filter design, neutron beam measurement dosimetry), and radiation biology (small and large animal models tissue studies and efficacy studies). Information on the potential toxicity of borocaptate sodium and boronophenylalanine is presented, results of 21 spontaneous-tumor-bearing dogs that have been treated with BNCT at the Brookhaven National Laboratory (BNL) Medical Research Reactor (BMRR) are discussed, and predictions for an epithermal-neutron beam at the Georgia Tech Research Reactor (GTRR) are shown. Cellular-level boron detection and localization by secondary ion mass spectrometry, sputter-initiated resonance ionization spectroscopy, low atomization resonance ionization spectroscopy, and alpha track are presented. Boron detection by ICP-AES is discussed in detail. Several boron carrying drugs exhibiting good tumor uptake are described. Significant progress in the potential of treating pituitary tumors with BNCT is presented. Measurement of the epithermal-neutron flux at BNL and comparison to predictions are shown. Calculations comparing the GTRR and BMRR epithermal-neutron beams are also presented. Individual progress reports described herein are separately abstracted and indexed for the database
Satisfactory Optimization Design of IIR Digital Filters
Jin Weidong; Zhang Gexiang; Zhao Duo
2005-01-01
A new method called satisfactory optimization method is proposed to design IIR (Infinite Impulse Response) digital filters, and the satisfactory optimization model is presented. The detailed algorithm of designing IIR digital filters using satisfactory optimization method is described. By using quantum genetic algorithm characterized by rapid convergence and good global search capability, the satisfying solutions are achieved in the experiment of designing lowpass and bandpass IIR digital filters. Experimental results show that the performances of IIR filters designed by the introduced method are better than those by traditional methods.
FPGA design and implementation of Gaussian filter
Yang, Zhihui; Zhou, Gang
2015-12-01
In this paper , we choose four different variances of 1,3,6 and 12 to conduct FPGA design with three kinds of Gaussian filtering algorithm ,they are implementing Gaussian filter with a Gaussian filter template, Gaussian filter approximation with mean filtering and Gaussian filter approximation with IIR filtering. By waveform simulation and synthesis, we get the processing results on the experimental image and the consumption of FPGA resources of the three methods. We set the result of Gaussian filter used in matlab as standard to get the result error. By comparing the FPGA resources and the error of FPGA implementation methods, we get the best FPGA design to achieve a Gaussian filter. Conclusions can be drawn based on the results we have already got. When the variance is small, the FPGA resources is enough for the algorithm to implement Gaussian filter with a Gaussian filter template which is the best choice. But when the variance is so large that there is no more FPGA resources, we can chose the mean to approximate Gaussian filter with IIR filtering.
Design Procedure for Compact Folded Waveguide Filters
Dong, Yunfeng; Johansen, Tom Keinicke; Zhurbenko, Vitaliy;
Waveguide filters are widely used in communication systems due to low losses and high power handling capabilities. One drawback of the conventional waveguide filters is their large size, especially for low-frequency and high-order realizations. It has been shown that the footprint of conventional...... waveguide resonators can be reduced to one quarter by folding the electric and magnetic fields inside the cavity (J. S. Hong, Microwave Symposium Digest, 2004, Vol. 1, pp. 213-216). This paper presents a novel systematic procedure for designing compact low-loss bandpass filters by using folded waveguide...... resonators. As a design example, a scaled version of a filter specified for a TETRA (Terrestrial Trunked Radio) system has been considered. The folded waveguide filter is designed to fulfil specific requirements, and the design procedure can be easily applied to other folded waveguide filter designs...
Performance analysis and design of filtering hydrocyclones
L. G. M. Vieira
2005-03-01
Full Text Available The filtering hydrocyclone is a solid-liquid separation device patented by the Chemical Engineering Department at the Federal University of Uberlândia, which consists of a hydrocyclone whose conical section was replaced by a conical filtering wall. The objective of this work is to compare the performances of the filtering hydrocyclones designed by Bradley and by Rietema. The experimental results obtained with the filtering hydrocyclones under the same operational conditions as those used with the conventional device allow the conclusion that performance of the Bradley and Rietema types is significantly influenced by the filtering medium. Rietema's filtering hydrocyclones had a lower volumetric feed flowrate than the conventional device and Bradley's filtering hydrocyclones showed increases in this same variable. In both designs, overall efficiency was influenced by the underflow-to-throughput ratio.
Design of energy filters for electron microscopes
Tsuno, Katsushige
1999-11-01
Software for simulating 3D electric and magnetic fields followed by the direct ray tracing in individual field and combined fields (EO3D, MO3D and CO3D) are well applied to the design of energy filters attached to electron microscopes. When we had designed a high resolution EELS instrument, we had no 3D software, and encountered problems in designing a retarding Wien filter used as the monochromator and analyzer. At that time, electric field homogeneity inside the gap of magnet and the deflection of beam at the fringing region due to the deviation of the Wien condition were unsolved problems. When we designed a low energy reflection electron microscope (LEEM), we had 3D software, and some of the above problems were solved. We used an arc shaped electrode for the beam separator and an eight-pole filter for the analyzer. The coincidence of the magnetic and electric fringing field distributions at the fringing regions (Wien condition) was not perfect but was improved. We have designed an omega filter for in-column energy filtered transmission electron microscope (EFTEM). The omega filter consists of four sector magnets. Optical behavior of the system is very complicated. First, we designed the filter by 2D approximation and then checked by electron trajectories by the 3D software. The designed omega filter works successfully.
Digital filter design for radar image formation
Adams, John W.; Nelson, Jeffrey E.; Banh, N. D.; Moncada, John J.; Bayma, Robert W.
1989-01-01
Novel weighted-least-squares approaches to the design of digital filters for SAR applications are presented. The filters belong to three different categories according to their combinations of minimax passband, least-squares stopband, minimax stopband, and maximally-flat passband. For real-time applications, it is important to design the sets of digital filter coefficient tables in an offline environment; the appropriate precomputed filter is then selected for each SAR signal-processing function, as a function of both mode and mapping geometry during real-time processing.
Analog Electronic Filters Theory, Design and Synthesis
Dimopoulos, Hercules G
2012-01-01
Filters are essential subsystems in a huge variety of electronic systems. Filter applications are innumerable; they are used for noise reduction, demodulation, signal detection, multiplexing, sampling, sound and speech processing, transmission line equalization and image processing, to name just a few. In practice, no electronic system can exist without filters. They can be found in everything from power supplies to mobile phones and hard disk drives and from loudspeakers and MP3 players to home cinema systems and broadband Internet connections. This textbook introduces basic concepts and methods and the associated mathematical and computational tools employed in electronic filter theory, synthesis and design. This book can be used as an integral part of undergraduate courses on analog electronic filters. Includes numerous, solved examples, applied examples and exercises for each chapter. Includes detailed coverage of active and passive filters in an independent but correlated manner. Emphasizes real filter...
Design of New SAW DQPSK Matched Filter
无
2006-01-01
A new surface acoustic wave differential quadraphase shift key(SAW DQPSK) spread spectrum(SS) signal matched filter based on the fusion of SS and differential modulation is reported. The design of multi-phase coded SAW matched filter is proposed rather than another design of SAW DQPSK filter, which can cut in a half of the delay time of SAW DQPSK matched filter and SAW fixed delay line(FDL) used for differential demodulation. This breakthrough is made the system largely reduce a size and process much easily. This method can also be feasible in other SAW MPSK matched filter design especially when the modulation phase number is larger than 4. The design example and its experimental results are given.
Design of Kalman filters for mobile robots
Larsen, Thomas Dall; Hansen, Karsten L.; Andersen, Nils Axel;
1999-01-01
Kalman filters have for a long time been widely used on mobile robots as a location estimator. Many different Kalman filter designs have been proposed, using models of various complexity. In this paper, two different design methods are evaluated and compared. Focus is put on the common setup where...... the mobile robot is equipped with a dual encoder system supported by some additional absolute measurements. A common filter type for this setup is the odometric filter, where readings from the odometry system on the robot are used together with the geometry of the robot movement as a model of the robot....... If additional kinematic assumptions are made, for instance regarding the velocity of the robot, an augmented model can be used instead. This kinematic filter has some advantages when used intelligently, and it is shown how this type of filter can be used to suppress noise on encoder readings and velocity...
Preliminary modeling of BNCT beam tube on IRT in Sofia
Belousov, S. [Institute for Nuclear Research and Nuclear Energy (INRNE) of the Bulgarian Academy of Sciences, Tsarigradsko 72, Sofia (Bulgaria)], E-mail: belousov@inrne.bas.bg; Ilieva, K. [Institute for Nuclear Research and Nuclear Energy (INRNE) of the Bulgarian Academy of Sciences, Tsarigradsko 72, Sofia (Bulgaria)
2009-07-15
The technical design of the research reactor IRT in Sofia is in progress. It includes an arrangement for a BNCT facility for tumor treatment. Modeling of geometry and material composition of filter/collimator for the BNCT beam tube on IRT has been carried out following the beam tube configuration of the Massachusetts Institute of Technology Reactor [Harling et al., 2002. The fission converter-based epithermal neutron irradiation facility at the Massachusetts Institute of Technology Reactor. Nucl. Sci. Eng. 140, 223-240.] and taking into account an ability to include the tube into the IRT reactor geometry. The results of neutron and gamma transport calculations performed for the model have shown that the facility will be able to supply an epithermal neutron flux of about 5x10{sup 9} n cm{sup -2} s{sup -1}, with low contamination from fast neutrons and gamma rays that would be among the best facilities currently available. An optimiziation study has been performed for the beam collimator, following similar studies for the TAPIRO research reactor in Italy. [Nava et al., 2005. Monte Carlo optimization of a BNCT facility for treating brain gliomas at the TAPIRO reactor. Radiat. Prot. Dosim. 116 (1-4), 475-481.].
Preliminary modeling of BNCT beam tube on IRT in Sofia
The technical design of the research reactor IRT in Sofia is in progress. It includes an arrangement for a BNCT facility for tumor treatment. Modeling of geometry and material composition of filter/collimator for the BNCT beam tube on IRT has been carried out following the beam tube configuration of the Massachusetts Institute of Technology Reactor [Harling et al., 2002. The fission converter-based epithermal neutron irradiation facility at the Massachusetts Institute of Technology Reactor. Nucl. Sci. Eng. 140, 223-240.] and taking into account an ability to include the tube into the IRT reactor geometry. The results of neutron and gamma transport calculations performed for the model have shown that the facility will be able to supply an epithermal neutron flux of about 5x109 n cm-2 s-1, with low contamination from fast neutrons and gamma rays that would be among the best facilities currently available. An optimiziation study has been performed for the beam collimator, following similar studies for the TAPIRO research reactor in Italy. [Nava et al., 2005. Monte Carlo optimization of a BNCT facility for treating brain gliomas at the TAPIRO reactor. Radiat. Prot. Dosim. 116 (1-4), 475-481.
BNCT activities at Slovenian TRIGA research reactor
It has been reported that satisfactory thermal/epithermal neutron beams for Boron Neutron Capture Therapy (BNCT) could be designed at TRIGA research reactors These reactors are generally perceived as being safe to install and operate in populated areas. This contribution presents the most recent BNCT research activities on the 'Jozef Stefan' Institute, where epithermal neutron beam for 'in-vitro' irradiation has been developed and experimentally verified. Furthermore, The Monte Carlo feasibility study of development of the epithermal neutron beam for BNCT clinical trials of human patients in thermalising column (TC) of TRIGA reactor has been carried out. The simulation results prove, that a BNCT irradiation facility with performances, comparable to existing beam throughout the world, could be installed in TC of the TRIGA reactor. (author)
Ridge filter design for carbon radiotherapy
The design of a ridge filter intended for forming the uniform spread-out Bragg peak within a tumor at carbon radiotherapy is described. The computation of the ridge filter shape was carried out by an analytical algorithm and tested by MC simulation (GEANT4 code). Two kinds of the ridge filter were considered: stationary and movable. The influence on a ridge filter shape of the carbon beam energy and type of relative biological effectiveness dependence on the carbon ion linear energy transfer in tissue were examined
Moisture reduction of filter cake by improved filter design
Dahlstrom, D.A.; Davis, S.S.; Garlick, L.D.
1983-10-01
With the redesign of the Agidisc filter, several improvements have been achieved as follows: Internal velocities of filtrate and air have been greatly reduced in the PIPPED sectors, ferrules, internal channels and filter valve. This will maximize pressure drop across the cake resulting in lower moistures and decreased wear. The PIPPED sector achieves better cake discharge because of the flexing action while increasing bag life. Moisture content reduction for the PIPPED sectors alone appear to have the potential for about 1 1/2 percentage points lower then redwood sectors. By indexing the two halves of the disc filter so each half discharges separately, shock wear on the cake conveyor should be reduced. More air volume will also go to less sectors resulting in better discharge. Using a sudden blow with a low pressure blower for cake discharge, energy consumption is reduced. Overall maintenance costs for the new design should be reduced through less wear due to appreciably reduced velocities.
Design rules for dislocation filters
The efficacy of strained layer threading dislocation filter structures in single crystal epitaxial layers is evaluated using numerical modeling for (001) face-centred cubic materials, such as GaAs or Si1−xGex, and (0001) hexagonal materials such as GaN. We find that threading dislocation densities decay exponentially as a function of the strain relieved, irrespective of the fraction of threading dislocations that are mobile. Reactions between threading dislocations tend to produce a population that is a balanced mixture of mobile and sessile in (001) cubic materials. In contrast, mobile threading dislocations tend to be lost very rapidly in (0001) GaN, often with little or no reduction in the immobile dislocation density. The capture radius for threading dislocation interactions is estimated to be approximately 40 nm using cross section transmission electron microscopy of dislocation filtering structures in GaAs monolithically grown on Si. We find that the minimum threading dislocation density that can be obtained in any given structure is likely to be limited by kinetic effects to approximately 104–105 cm−2
Design rules for dislocation filters
Ward, T.; Sánchez, A. M.; Beanland, R., E-mail: r.beanland@warwick.ac.uk [Department of Physics, University of Warwick, Coventry CV4 7AL (United Kingdom); Tang, M.; Wu, J.; Liu, H. [Department of Electronic and Electrical Engineering, University College London, Torrington Place, London WC1E 7JE (United Kingdom); Dunstan, D. J. [School of Physics and Astronomy, Queen Mary University of London, London E1 4NS (United Kingdom)
2014-08-14
The efficacy of strained layer threading dislocation filter structures in single crystal epitaxial layers is evaluated using numerical modeling for (001) face-centred cubic materials, such as GaAs or Si{sub 1−x}Ge{sub x}, and (0001) hexagonal materials such as GaN. We find that threading dislocation densities decay exponentially as a function of the strain relieved, irrespective of the fraction of threading dislocations that are mobile. Reactions between threading dislocations tend to produce a population that is a balanced mixture of mobile and sessile in (001) cubic materials. In contrast, mobile threading dislocations tend to be lost very rapidly in (0001) GaN, often with little or no reduction in the immobile dislocation density. The capture radius for threading dislocation interactions is estimated to be approximately 40 nm using cross section transmission electron microscopy of dislocation filtering structures in GaAs monolithically grown on Si. We find that the minimum threading dislocation density that can be obtained in any given structure is likely to be limited by kinetic effects to approximately 10{sup 4}–10{sup 5 }cm{sup −2}.
Polychromator filter design with genetic algorithm
In Thomson scattering (TS) diagnostics, polychromators are equipped with several optical band-pass filters which cover the spectral region where the radiation from the incident laser beam is expected to be Doppler shifted. The spectral location of the transmission band of individual filters has a strong influence on the measured electron temperature (Te) since the latter is derived from a previously computed lookup table including the spectral specifications of the filters. Here, we present the design of the set of polychromator filters through genetic algorithms (GAs). We examine the developed algorithm under two specific target conditions, and optimized filter sets covering the wavelength region longer than the wavelength of the incident laser seem to be more effective in improving the accuracy of the Te calculations provided by the diagnostic. (paper)
Design of withdrawal-weighted SAW filters.
Lee, Youngjin; Lee, Seunghee; Roh, Yongrae
2002-03-01
This paper presents a new design algorithm for a withdrawal-weighted surface acoustic wave (SAW) transversal filter. The proposed algorithm is based on the effective transmission loss theory and a delta function model of a SAW transversal filter. The design process consists of three steps, which eventually determine eight geometrical design parameters for the filter in order to satisfy given performance specifications. First, the number of fingers in the input and output interdigital transducers (IDTs), plus their geometrical sizes is determined using the insertion loss specification. Second, the number and positions of the polarity reverses in the output IDT are determined using the bandwidth and ripple specifications. Third, the number and position for withdrawing and switching specific fingers in the output IDT and attached electrode area are determined to achieve the desired sidelobe level. The efficiency of the technique is illustrated using a sample design of an IF filter consisting of a uniform input IDT and withdrawal-weighted output IDT. The proposed algorithm is distinct from conventional techniques in that it can optimize the structural geometry of a withdrawal-weighted SAW filter in a direct manner by considering all the performance specifications simultaneously. PMID:12322883
Quenching the anion generated from a 2-(ω-carboranylalkyl)dithiane with 2H2O at -78oC and at 0oC introduced deuterium exclusively at C-2 of the carborane. Extension of this model reaction to a bioreductively-targetted carborane allowed the synthesis of 2-[2H]- and 2-[3H]-isotopomers of a nitroimidazole-carborane which is of interest in boron neutron capture therapy (BNCT) of cancer. (author)
The activity in accelerator development for accelerator-based BNCT (AB-BNCT) both worldwide and in Argentina is described. Projects in Russia, UK, Italy, Japan, Israel, and Argentina to develop AB-BNCT around different types of accelerators are briefly presented. In particular, the present status and recent progress of the Argentine project will be reviewed. The topics will cover: intense ion sources, accelerator tubes, transport of intense beams, beam diagnostics, the 9Be(d,n) reaction as a possible neutron source, Beam Shaping Assemblies (BSA), a treatment room, and treatment planning in realistic cases. - Highlights: • The activity in accelerator development for accelerator-based BNCT (AB-BNCT) both worldwide and in Argentina is described. • Projects in Russia, UK, Italy, Japan, Israel, and Argentina to develop AB-BNCT around different types of accelerators are briefly presented. • The present status and recent progress of the Argentine project will be reviewed. • Topics cover intense ion sources, accelerator tubes, transport of intense beams and beam diagnostics, among others
BNCT with linac, feasibility study
High energy photon beams from Medical Linear Accelerators (linacs) which are used in radiotherapy produce undesirable neutrons, beside the clinically useful electron and photon beams. Neutrons are produced from the photonuclear reaction (γ,n) of high energy photons with high Z-materials which compose the accelerator head. In this paper the possible use of these undesirable neutrons for BNCT is investigated, making use of high energy linacs already installed in hospitals, primarily for high energy electron and photon therapy and applying them in the context of BNCT. The photoneutron components emitted by the accelerator is the source for Monte Carlo simulations of the interactions that take place within the head of a voxel-based phantom. The neutron flux across the phantom head is calculated using different moderator arrangements and different techniques in the aim of increasing the thermal neutron flux at the targeted site. Also, we shall test different configurations of the linac head to maximize the exposure of high-Z materials to the photon beam, including the removal of the flattening filter, so as to boost the photoneutron production in the linac head. Experimental work will be conducted in hospitals to validate the Monte Carlo simulations. To make use of linacs for BNCT will be advantageous in the sense that the setting in a hospital department is much more acceptable by the public than a reactor installation. This will mean less complications regarding patient positioning and movement with respect to the beams, additional patient transportation and management will be more cost effective. (author)
High neutronic efficiency, low current targets for accelerator-based BNCT applications
The neutronic efficiency of target/filters for accelerator-based BNCT applications is measured by the proton current required to achieve a desirable neutron current at the treatment port (109 n/cm2/s). In this paper the authors describe two possible targeyt/filter concepts wihch minimize the required current. Both concepts are based on the Li-7 (p,n)Be-7 reaction. Targets that operate near the threshold energy generate neutrons that are close tothe desired energy for BNCT treatment. Thus, the filter can be extremely thin (∼ 5 cm iron). However, this approach has an extremely low neutron yield (n/p ∼ 1.0(-6)), thus requiring a high proton current. The proposed solutino is to design a target consisting of multiple extremely thin targets (proton energy loss per target ∼ 10 keV), and re-accelerate the protons between each target. Targets operating at ihgher proton energies (∼ 2.5 MeV) have a much higher yield (n/p ∼ 1.0(-4)). However, at these energies the maximum neutron energy is approximately 800 keV, and thus a neutron filter is required to degrade the average neutron energy to the range of interest for BNCT (10--20 keV). A neutron filter consisting of fluorine compounds and iron has been investigated for this case. Typically a proton current of approximately 5 mA is required to generate the desired neutron current at the treatment port. The efficiency of these filter designs can be further increased by incorporating neutron reflectors that are co-axial with the neutron source. These reflectors are made of materials which have high scattering cross sections in the range 0.1--1.0 MeV
A Novel Filter Bank Design Method with CEM FRM Technique
Li-Zhi Zhang; Wen-Yu Luo
2009-01-01
Modulation filter banks can be obtained by modulating one or two prototype filters, which reduce the design complexity of the filter banks. Furthermore, this kind of filter can be realized by using DFT or FFT with very high computationally efficiency. The proposition of a modulation filter bank reduces the computation complexity of designing the filter bank consumedly, which has very high computation efficiency. However, with the increasing of channels, the request for transition of the proto...
Design of spectral filtering for tissue classification
Narayanan, Ajay; Shah, Pratik; Das, Bipul
2012-02-01
Tissue characterization from imaging studies is an integral part of clinical practice. We describe a spectral filter design for tissue separation in dual energy CT scans obtained from Gemstone Spectral Imaging scanner. It enables to have better 2D/3D visualization and tissue characterization in normal and pathological conditions. The major challenge to classify tissues in conventional computed tomography (CT) is the x-ray attenuation proximity of multiple tissues at any given energy. The proposed method analyzes the monochromatic images at different energy levels, which are derived from the two scans obtained at low and high KVp through fast switching. Although materials have a distinct attenuation profile across different energies, tissue separation is not trivial as tissues are a mixture of different materials with range of densities that vary across subjects. To address this problem, we define spectral filtering, that generates probability maps for each tissue in multi-energy space. The filter design incorporates variations in the tissue due to composition, density of individual constituents and their mixing proportions. In addition, it also provides a framework to incorporate zero mean Gaussian noise. We demonstrate the application of spectral filtering for bone-free vascular visualization and calcification characterization.
BNCT. Computational Analysis; BNCT. Analisis computacional
Caro, R.
2004-07-01
The BNCT (Boron Neutron Capture Therapy) is a new oncologic radiotherapy technique in the process of research which consists of injecting a non-poisonous pharmacovector into an ill patient in such a way that the tumor receives isotope boron-10, so that the tumoral area can later be bombarded with a beam of neutrons, many of which are captured the isotope in question. (Author)
Design and application of finite impulse response digital filters
The finite impulse response (FIR) digital filter is a spatial domain filter with a frequency domain representation. The theory of the FIR filter is presented and techniques are described for designing FIR filters with known frequency response characteristics. Rational design principles are emphasized based on characterization of the imaging system using the modulation transfer function and physical properties of the imaged objects. Bandpass, Wiener, and low-pass filters were designed and applied to 201Tl myocardial images. The bandpass filter eliminates low-frequency image components that represent background activity and high-frequency components due to noise. The Wiener, or minimum mean square error filter 'sharpens' the image while also reducing noise. The Wiener filter illustrates the power of the FIR technique to design filters with any desired frequency reponse. The low-pass filter, while of relative limited use, is presented to compare it with a popular elementary 'smoothing' filter. (orig.)
Design of Microwave Multibandpass Filters with Quasilumped Resonators
Dejan Miljanović; Milka Potrebić; Tošić, Dejan V.
2015-01-01
Design of RF and microwave filters has always been the challenging engineering field. Modern filter design techniques involve the use of the three-dimensional electromagnetic (3D EM) solvers for predicting filter behavior, yielding the most accurate filter characteristics. However, the 3D EM simulations are time consuming. In this paper, we propose electric-circuit models, instead of 3D EM models, suitable for design of RF and microwave filters with quasilumped coupled resonators. Using the d...
American brain tumor patients treated with BNCT in Japan
The purpose of this work is to establish and maintain a database for patients from the United States who have received BNCT in Japan for malignant gliomas of the brain. This database will serve as a resource for the DOE to aid in decisions relating to BNCT research in the United States, as well as assisting the design and implementation of clinical trials of BNCT for brain cancer patients in this country. The database will also serve as an information resource for patients with brain tumors and their families who are considering this form of therapy
American brain tumor patients treated with BNCT in Japan
Laramore, G.E.; Griffin, B.R.; Spence, A.
1995-11-01
The purpose of this work is to establish and maintain a database for patients from the United States who have received BNCT in Japan for malignant gliomas of the brain. This database will serve as a resource for the DOE to aid in decisions relating to BNCT research in the United States, as well as assisting the design and implementation of clinical trials of BNCT for brain cancer patients in this country. The database will also serve as an information resource for patients with brain tumors and their families who are considering this form of therapy.
Dose estimation of the THOR BNCT treatment room
BNCT beam of Tsing Hua Open-pool Reactor (THOR) was designed and constructed since 1998. A treatment room for the newly modified THOR BNCT beam was constructed for the next clinical-stage trials in 2004. Dose distribution in a patient (or a phantom) is important as irradiated with the BNCT beam. The dose distributions for different type of radiations such as neutron and photons in the treatment room are strongly becoming the index or reference of success for a BNCT facility. An ART head phantom was placed in front of the THOR BNCT beam port and was irradiated. In each section of the head phantom, numbers of small holes are inside and separated uniformly. Dual detector: TLD-600 and TLD-700 chips were placed inside these holes within the phantom to distinct doses of neutron and photon. Besides, Dual-TLD chips were latticed placed in the horizontal plane of beam central axis, in the treatment room to estimate the spatial dose distribution of neutron and photon. Gold foils were assisted in TLD dose calibrations. Neutron and photon dose distributions in phantom and spatial dose distributions in the THOR BNCT treatment room were both estimated in this work. Testing and improvement in THOR BNCT beam were continuative during these years. Results of this work could be the reference and be helpful for the further clinical trials in nearly future. (author)
Ackermann, A.L. (ed.)
1991-08-01
This Bulletin presents a summary of accomplishments and highlights in the Idaho National Engineering Laboratory's (INEL) Boron Neutron Capture Therapy (BNCT) Program for August 1991. This bulletin includes information on the brain tumor and melanoma research programs, Power Burst Facility (PBF) technical support and modifications, PBF operations, and updates to the animal data charts.
BNCT-RTPE: BNCT radiation treatment planning environment
Wessol, D.E.; Wheeler, F.J. [Idaho National Engineering Lab., Idaho Fall, ID (United States); Babcock, R.S. [and others
1995-11-01
Several improvements have been developed for the BNCT radiation treatment planning environment (BNCT-Rtpe) during 1994. These improvements have been incorporated into Version 1.0 of BNCT-Rtpe which is currently installed at the INEL, BNL, Japanese Research Center (JRC), and Finland`s Technical Research Center. Platforms supported by this software include Hewlett-Packard (HP), SUN, International Business Machines (IBM), and Silicon Graphics Incorporated (SGI). A draft version of the BNCT-Rtpe user manual is available. Version 1.1 of BNCT-Rtpe is scheduled for release in March 1995. It is anticipated that Version 2.x of BNCT-Rtpe, which includes the nonproprietary NURBS library and data structures, will be released in September 1995.
New EORTC clinical trials for BNCT
Due to ethical reasons, a separated optimization of the two components of BNCT in the frame of clinical investigations can only be performed applying the whole binary system. The ongoing trial at HFR (High Flux Reactor Petten) has proven the feasibility of BNCT under defined conditions. On that basis the European Commission supported a comprehensive research project on boron imaging including three further clinical studies. In the first trial the boron uptake related to the blood boron concentration and surrounding normal tissue in various solid tumours will be examined using BSH (Sodiumborocaptate), BPA (Boronophenylalanine) or both in order to explore tumour entities, which may gain benefit from BNCT. The major objectives of the second trial are to define the maximum tolerated single and cumulative dose, and the dose limiting toxicity of BSH. The third clinical trial, a phase II study is designed to evaluate the anti-tumour effect of fractionated BNCT at the Petten treatment facility against cerebral metastasis of malignant melanoma using BPA. (author)
Optimization of the irradiation beam in the BNCT research facility at IEA-R1 reactor
Boron Neutron Capture Therapy (BNCT) is a radiotherapeutic technique for the treatment of some types of cancer whose useful energy comes from a nuclear reaction that occurs when thermal neutron impinges upon a Boron-10 atom. In Brazil there is a research facility built along the beam hole number 3 of the IEA-R1 research reactor at IPEN, which was designed to perform BNCT research experiments. For a good performance of the technique, the irradiation beam should be mostly composed of thermal neutrons with a minimum as possible gamma and above thermal neutron components. This work aims to monitor and evaluate the irradiation beam on the sample irradiation position through the use of activation detectors (activation foils) and also to propose, through simulation using the radiation transport code, MCNP, new sets of moderators and filters which shall deliver better irradiation fields at the irradiation sample position In this work, a simulation methodology, based on a MCNP card, known as wwg (weight window generation) was studied, and the neutron energy spectrum has been experimentally discriminated at 5 energy ranges by using a new set o activation foils. It also has been concluded that the BNCT research facility has the required thermal neutron flux to perform studies in the area and it has a great potential for improvement for tailoring the irradiation field. (author)
Design of high frequency integrated analogue filters
Sun, Yichuang
2002-01-01
This book brings together leading researchers to highlight recent advances and identify promising directions for future development. Motivated by the market for mobile and wireless communications, fully integrated analog filters for high-frequency applications are now receiving great interest world-wide. Chapters are dedicated to MOSFET-C and Gm-C filters, current-mode continuous-time filters, log-domain filters, switched-current filters, adaptive filters and on-chip automatic tuning. The topical nature of the book and caliber of the authors ensures that this book will be of wide interest to t
Design of LCL-Filter Based Three-level Active Power Filter
Shilan Chen
2013-07-01
Full Text Available This paper proposes an improved design of LCL-Filters for Three-Level Shunt Active power filters (APF. Available design principles are presented to achieve high compensation bandwidth and low switching frequency current. Then, affecitons of different parameters are taken into consideration of constraints on LCL-Filter design with detail analysis of ripple current. A simple and practical design procedure of LCL-Filter for Three-Level APF is subsequently proposed. The first step is to choose the resonant frequency of LCL-Filter according to the highest order harmonic needed to be compensated. Then it is aim to optimize the parameters of the LCL-Filter based on the design principles and constraints. The simulation results verify the effectiveness of the proposed method.
As part of the joint project on extra-corporal treatment of liver cancer by BNCT between JRC Petten and the University Hospital Essen, a facility has been designed and built to contain the liver during its irradiation treatment at the HFR Petten. The design consists of a rotating spheroid shaped PMMA holder, manufactured to open at the equator and closed by screwing together, surrounded by PMMA and graphite blocks. A validation exercise has been performed regarding both the nuclear conditions and the physical conditions. For the former, activation foil sets of Au, Cu and Mn, were irradiated at positions inside the liver holder filled with water, whilst a second measurement campaign has been performed using gel dosimetry. For the physical test, it is required to operate (rotate) the facility for up to 4 hours and to maintain the liver at approximately 4degC. The latter test was performed using 'cold gun sprays' that inject cold air near the liver holder. Both the nuclear and physical validation tests were performed successfully. (author)
Researches on Parameters Calculation of Designing Double-tuned Filter
HE Yi-hong; Su, Heng
2013-01-01
Aiming at the question of parameter of double-tuned filter, A new method of designing double-tuned filter was proposed based on resonance frequency, by using the relationship that the impedance of double-tund filter and two parallel single tuned filters is equal and the resonance frequency of single tuned filter is the zero of the impedance of double-tuned filter. A simulation was established to prove the correctness of this method by using the software MATLAB in a power system. Simulation r...
An Accelerator Neutron Source for BNCT
The overall goal of this project was to develop an accelerator-based neutron source (ABNS) for Boron Neutron Capture Therapy (BNCT). Specifically, our goals were to design, and confirm by measurement, a target assembly and a moderator assembly that would fulfill the design requirements of the ABNS. These design requirements were (1) that the neutron field quality be as good as the neutron field quality for the reactor-based neutron sources for BNCT, (2) that the patient treatment time be reasonable, (3) that the proton current required to treat patients in reasonable times be technologically achievable at reasonable cost with good reliability, and accelerator space requirements which can be met in a hospital, and finally (4) that the treatment be safe for the patients
An Accelerator Neutron Source for BNCT
Blue, Thomas, E
2006-03-14
The overall goal of this project was to develop an accelerator-based neutron source (ABNS) for Boron Neutron Capture Therapy (BNCT). Specifically, our goals were to design, and confirm by measurement, a target assembly and a moderator assembly that would fulfill the design requirements of the ABNS. These design requirements were 1) that the neutron field quality be as good as the neutron field quality for the reactor-based neutron sources for BNCT, 2) that the patient treatment time be reasonable, 3) that the proton current required to treat patients in reasonable times be technologially achievable at reasonable cost with good reliability, and accelerator space requirements which can be met in a hospital, and finally 4) that the treatment be safe for the patients.
Some portion of the radiation dose received by a patient during BNCT consists of primary and secondary gammas. The biological effect of that portion of the dose will depend upon the time history of the delivered dose. The well-known models for relating time-dose effects to clinical experience, are of questionable value in understanding dose effects in the time regime of a few hours, and for doses of less than tolerance. In order to examine the time-dose effect in the regime of interest to BNCT a simple phenomenological model was developed and normalized to the accepted body of clinical experience. The model has been applied to the question of fractionation of BNCT and the results are presented. The model is simply a linear healing model with two time constants. In other words, a first hit of radiation is assumed to wound (or potentiate) a cell. Given time, the cell will fully repair itself. If a second hit occurs before the cell has healed, the cell is killed. Apparently, there are two kinds of healing, one which occurs in 30 to 60 minutes, the other in two to four days. A small fraction of the cells will die on the first hit
Design of Microwave Multibandpass Filters with Quasilumped Resonators
Dejan Miljanović
2015-01-01
Full Text Available Design of RF and microwave filters has always been the challenging engineering field. Modern filter design techniques involve the use of the three-dimensional electromagnetic (3D EM solvers for predicting filter behavior, yielding the most accurate filter characteristics. However, the 3D EM simulations are time consuming. In this paper, we propose electric-circuit models, instead of 3D EM models, suitable for design of RF and microwave filters with quasilumped coupled resonators. Using the diakoptic approach, the 3D filter structure is decomposed into domains that are modeled by electric networks. The coupling between these domains is modeled by capacitors and coupled inductors. Furthermore, we relate the circuit-element values to the physical dimensions of the 3D filter structure. We propose the filter design procedure that is based on the circuit models and fast circuit-level simulations, yielding the element values from which the physical dimensions can be obtained. The obtained dimensions should be slightly refined for achieving the desired filter characteristics. The mathematical problems encountered in the procedure are solved by numerical and symbolic computations. The procedure is exemplified by designing a triple-bandpass filter and validated by measurements on the fabricated filter. The simulation and experimental results are in good agreement.
Frequency weighting filter design for automotive ride comfort evaluation
Du, Feng
2016-04-01
Few study gives guidance to design weighting filters according to the frequency weighting factors, and the additional evaluation method of automotive ride comfort is not made good use of in some countries. Based on the regularities of the weighting factors, a method is proposed and the vertical and horizontal weighting filters are developed. The whole frequency range is divided several times into two parts with respective regularity. For each division, a parallel filter constituted by a low- and a high-pass filter with the same cutoff frequency and the quality factor is utilized to achieve section factors. The cascading of these parallel filters obtains entire factors. These filters own a high order. But, low order filters are preferred in some applications. The bilinear transformation method and the least P-norm optimal infinite impulse response(IIR) filter design method are employed to develop low order filters to approximate the weightings in the standard. In addition, with the window method, the linear phase finite impulse response(FIR) filter is designed to keep the signal from distorting and to obtain the staircase weighting. For the same case, the traditional method produces 0.330 7 m • s-2 weighted root mean square(r.m.s.) acceleration and the filtering method gives 0.311 9 m • s-2 r.m.s. The fourth order filter for approximation of vertical weighting obtains 0.313 9 m • s-2 r.m.s. Crest factors of the acceleration signal weighted by the weighting filter and the fourth order filter are 3.002 7 and 3.011 1, respectively. This paper proposes several methods to design frequency weighting filters for automotive ride comfort evaluation, and these developed weighting filters are effective.
Design and Analysis of Robust Active Damping for LCL Filters using Digital Notch Filters
Yao, Wenli; Yang, Yongheng; Zhang, Xiaobin;
2016-01-01
resonance, where the notch frequency should be aligned exactly to the resonant frequency of the LCL filter. However, parameter variations of the LCL filter as well as the time delay appearing in digital control systems will induce resonance drifting, and thus break this alignment, possibly deteriorating the......Resonant poles of LCL filters may challenge the entire system stability especially in digital-controlled Pulse Width Modulation (PWM) inverters. In order to tackle the resonance issues, many active damping solutions have been reported. For instance, a notch filter can be employed to damp the......-connected PWM inverter verify the effectiveness of the proposed design for robust active damping using digital notch filters....
Design and control of LCL-filter with active damping for Active Power Filter
Zeng, Guohong; Rasmussen, Tonny Wederberg; Ma, L;
2010-01-01
In the application of shunt Active Power Filter (APF) to compensate nonlinear load's harmonic, reactive and negative sequence current, it is more effective to use a LCL-filter than an L-filter as an interface between the Voltage Source Converter (VSC) and grid. In this paper, a designing procedure...... of LCL-filter for APF is introduced, which is aimed for simplified the implementation. To suppress the resonance that may be excited in the system, which brings in stability problems, an active damping control strategy using the current feed-back of the filter capacitor is adopted. By selecting two equal...... or similar inductances, the filter designing become more simple and effective, meanwhile the capacitance requirement is minimized. A pole-zero automatic cancellation phenomenon is discussed in this paper, which can be applied to simplify the current regulator designing. The tuning method is presented, based...
A virtual model of the patient's head for BNCT
The aim of the present work was creating a virtual phantom of a human head for BNCT, as a part of the BNCT programme project. This model is an amplification of the simple model described in earlier publications. It takes into account the major head organs as well as the scalp and skull. The chemical composition of all tissues was modelled according to the recommendations of the ICRP. The organs were parameterized using mathematical formulas based on the human head magnetic resonance images. The model was used for calculating the thermal neutron flux and the injuring (fast neutron, nitrogen and gamma) dose components for the head irradiated using the therapeutic neutron beam, whose parameters were obtained as the result of the modelling of the filter/moderator system for the BNCT therapeutic beam from the MARIA reactor. (authors)
Noniterative Design of 2-Channel FIR Orthogonal Filters
Jiménez M Elena Domínguez
2007-01-01
Full Text Available This paper addresses the problem of obtaining an explicit expression of all real FIR paraunitary filters. In this work, we present a general parameterization of 2-channel FIR orthogonal filters. Unlike other approaches which make use of a lattice structure, we show that our technique designs any orthogonal filter directly, with no need of iteration procedures. Moreover, in order to design an -tap 2-channel paraunitary filterbank, it suffices to choose independent parameters, and introduce them in a simple expression which provides the filter coefficients directly. Some examples illustrate how this new approach can be used for designing filters with certain desired properties. Further conditions can be eventually imposed on the parameters so as to design filters for specific applications.
Asis Mazumder; Pankaj Kumar Roy; Rabindra Nath Barman; Biswajit Mukhopadhay; Mrinmoy Majumder
2008-01-01
The general objective of this study is to estimate the performance of the Horizontal Roughing Filter (HRF) by using Weglin's design criteria based on 1/3–2/3 filter theory. The main objective of the present study is to validate HRF developed in the laboratory with Slow Sand Filter (SSF) as a pretreatment unit with the help of Weglin's design criteria for HRF with respect to raw water condition and neuro-genetic model developed based on the filter dataset. The results achieved from t...
Filter Design With Secrecy Constraints: The MIMO Gaussian Wiretap Channel
Reboredo, Hugo; Xavier, Joao; Rodrigues, Miguel R. D.
2013-08-01
This paper considers the problem of filter design with secrecy constraints, where two legitimate parties (Alice and Bob) communicate in the presence of an eavesdropper (Eve), over a Gaussian multiple-input-multiple-output (MIMO) wiretap channel. This problem involves designing, subject to a power constraint, the transmit and the receive filters which minimize the mean-squared error (MSE) between the legitimate parties whilst assuring that the eavesdropper MSE remains above a certain threshold. We consider a general MIMO Gaussian wiretap scenario, where the legitimate receiver uses a linear Zero-Forcing (ZF) filter and the eavesdropper receiver uses either a ZF or an optimal linear Wiener filter. We provide a characterization of the optimal filter designs by demonstrating the convexity of the optimization problems. We also provide generalizations of the filter designs from the scenario where the channel state is known to all the parties to the scenario where there is uncertainty in the channel state. A set of numerical results illustrates the performance of the novel filter designs, including the robustness to channel modeling errors. In particular, we assess the efficacy of the designs in guaranteeing not only a certain MSE level at the eavesdropper, but also in limiting the error probability at the eavesdropper. We also assess the impact of the filter designs on the achievable secrecy rates. The penalty induced by the fact that the eavesdropper may use the optimal non-linear receive filter rather than the optimal linear one is also explored in the paper.
Review on Desing Beam Shaping Assembly Based on the D-T Reaction for BNCT
Boron Neutron Capture Therapy (BNCT) can be achieved using a compact high energy neutron generator, in which the neutron energy should be in the epithermal range (1 eV < E < 10 keV) with high epithermal flux for treating Glioblastoma Multiforme (GBM). For this purpose, a suitable Beam Shaping Assembly (BSA) of a D-T neutron source is required. A major advantage of a D-T neutron source is the low energy required for the deuteron beam, namely 400 keV. The BSA design consists of a neutron multiplier, a moderator, a reflector, a fast neutron filter, a thermal neutron filter, gamma shielding and a collimator. In this work, the simulation code MCNP-4C is used to simulate the suggested BSA design as given in the literature. Beam parameters obtained by the proposed BSA design for the D-T neutron generator are investigated based on the IAEA recommendation. The results will be presented and discussed, which can provide an appropriate neutron beam for BNCT and suitable for planning in-hospital installations.
Optimal wavelet filter bank design for image fusion
Gang Liu; Xueqin Lü; Guohong Huang
2007-01-01
A novel optimization-based method for designing wavelet filter banks in image fusion is proposed. The filter bank design is formulated as a nonlinear optimization problem. The objective function of the optimization problem consists of both the performance metrics of the image fusion, such as the root mean square error (RMSE), and those of individual filters. The optimization problem is solved using simulating annealing.
Development of Graphical User Interface For Microwave Filter Design
Gerard, Djengomemgoto
2016-01-01
This research project aims at developing a low-cost, time-effective and a stand-alone graphical user interface (GUI) that will be used to design microwave filters. Throughout the projects, the main theory behind the technology of microwave filters, their generalized mathematical equations and the analysis of their different circuit topologies have been reviewed. This review helps to extract the necessary information needed for the design of microwave filters. Besides, the guiding principles a...
The Hardware Design of Parameter-Adjustable FIR Filter System
Guosheng Xu
2013-01-01
This design using FPGA parallel architecture, high computing speed and high-speed reliability of USB2.0 interface, designed an FPGA + USB2.0 + computer FIR digital filter system, organically combining the speed of FPGA and flexibility of Computer through USB2.0 bus. The results demonstrated that the coefficients configuring of the system is easy, which can adjust the filter coefficients flexibly according to the actual demand, that it can effectively filter out the noise signals.
Software Would Largely Automate Design of Kalman Filter
Chuang, Jason C. H.; Negast, William J.
2005-01-01
Embedded Navigation Filter Automatic Designer (ENFAD) is a computer program being developed to automate the most difficult tasks in designing embedded software to implement a Kalman filter in a navigation system. The most difficult tasks are selection of error states of the filter and tuning of filter parameters, which are timeconsuming trial-and-error tasks that require expertise and rarely yield optimum results. An optimum selection of error states and filter parameters depends on navigation-sensor and vehicle characteristics, and on filter processing time. ENFAD would include a simulation module that would incorporate all possible error states with respect to a given set of vehicle and sensor characteristics. The first of two iterative optimization loops would vary the selection of error states until the best filter performance was achieved in Monte Carlo simulations. For a fixed selection of error states, the second loop would vary the filter parameter values until an optimal performance value was obtained. Design constraints would be satisfied in the optimization loops. Users would supply vehicle and sensor test data that would be used to refine digital models in ENFAD. Filter processing time and filter accuracy would be computed by ENFAD.
Design of Compact UWB Bandpass Filter with Sharp Rejection Characteristics
Gyuje Sung
2014-07-01
Full Text Available This study presents an Ultra-Wideband (UWB filter with sharp rejection characteristics at the upper Wireless Local Area Network (WLAN band. The filter adopts the modified Composite Right/Left-Handed (CRLH Transmission Lines (TLs, the unit cell of which is theoretically analyzed to derive the design formulas. Subsequently, a UWB bandpass filter is designed using these formulas. The measurement results show that the fabricated UWB bandpass filter has an insertion loss of less than 1.1 dB, bandwidth of 3.1~4.9 GHz and a rejection of more than 50 dB at 5.8 GHz.
An Ant Colony Optimization Algorithm for Microwave Corrugated Filters Design
Mantilla-Gaviria, Ivan A.; Alejandro Díaz-Morcillo; Balbastre-Tejedor, Juan V.
2013-01-01
A practical and useful application of the Ant Colony Optimization (ACO) method for microwave corrugated filter design is shown. The classical, general purpose ACO method is adapted to deal with the microwave filter design problem. The design strategy used in this paper is an iterative procedure based on the use of an optimization method along with an electromagnetic simulator. The designs of high-pass and band-pass microwave rectangular waveguide filters working in the C-band and X-band, res...
Design of Tunable Multiple- Cavity Filter for Optical Fiber Communication
Vahideh Khadem Hosseini Ghasemi
2013-07-01
Full Text Available In this paper a new type of cavity filter is investigated. The device is based on a Fabry–Perot interferometer which employing a cavity and two dielectric Bragg mirrors. The cavity filter uses multi layers of ( and (ZnS to produce a multi -layers ZnS/ cavity filter operating in the center wavelength of 1550 (nm. Zinc sulfide is used in this paper due to its high refractive index, while due to its low refractive index material. The filter is to be coated on Fused Silica having the index of 1.55 and operates at normal incidence. The ZnS/ thin film structure was designed using the Thin Film Design software (TF Calc. The simulation results show that the transmittance of the ZnS/ filter is about 95% for central wavelength of 1550 nm. This filter is essential for monitoring and reconfiguring optical networks.
Design of HTS transmit filter using step impedance resonators
Sekiya, N., E-mail: nsekiya@yamanashi.ac.j [University of Yamanashi, 4-3-11 Takeda, Kofu 400-8511 (Japan); Nakagawa, Y. [University of Yamanashi, 4-3-11 Takeda, Kofu 400-8511 (Japan); Ohshima, S. [Yamagata University, 4-3-16 Johnan, Yonezawa 992-8510 (Japan)
2010-11-01
We have designed a high-temperature superconducting (HTS) transmit filter with step impedance resonators (SIRs). A transmit filter using half-wavelength straight-line resonators requires substantial spacing between adjacent resonators. This means that the filter needs a large substrate and that the number of poles is limited. Using SIRs overcomes this problem because SIRs are compact and have weak coupling. An electromagnetic simulator based on the moment method was used to design the SIR filter, which has a center frequency of 5 GHz and a bandwidth of 120 MHz. Simulation showed that it is approximately 19% smaller than a conventional half-wavelength straight-line resonator filter. Additionally, the maximum surface current is approximately 17% less than that of the conventional filter.
Robust Two-Dimensional FIR Filter Design for Broadband Beamformers
Nordebo, Sven
1995-01-01
With conventional least squares or Chebyshev approximation methods in the design of a fixed, broadband, delay{and{sum beamformer, the filter weight values may become excessively large. This anomaly is due to large, unspecified regions of the corresponding two{dimensional FIR filter frequency plane. With large filter weight values, the frequency response of the resulting beamformer may be severely degraded due to inaccuracies in sensor positions and/or sensor frequency response. For an adaptiv...
BNCT irradiation facility at the JRR-4
Torii, Y.; Kishi, T.; Kumada, H.; Yamamoto, K.; Sakurai, F.; Takayanagi, M. [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment
2000-10-01
The JRR--4 was modified for fuel enrichment reducing and reactor equipment renewal. And also a medical irradiation facility for the Boron Neutron Capture Therapy (BNCT) was installed at the JRR--4 in that time. The medical irradiation facility has been composed of a heavy water tank, a collimator and an irradiation room. The heavy water tank has four layers of heavy water for spectrum shifter and 75cm-thickness aluminum for the shield of fast neutron. The collimator is for collimating thermal neutron and epithermal neutron using polyethylene with lithium-fluoride and shielding gamma ray by bismuth. The irradiation room has sufficient space at exit side of the beam, to accommodate a large working area for setting the patient. Both of the medical treatment room and the patient-monitoring area were prepared adjacent to the irradiation room. The medical irradiation facility in the JRR-4 is designed to permit selection of neutron energies from thermal neutron to epithermal neutron by changing the thickness of heavy water layers. Therefore it is available to continue the same kind of BNCT with thermal neutron used to perform in the JRR-2, as well as to commence the research and development of BNCT with epithermal neutron, which will make the brain tumor treatment possible at a deep part of brain. The full power operation of the JRR-4 was resumed with LEU fuel in October 1998 and currently performing some experiments to measure the neutron fluxes and physical doses for determinate characterization of the medical irradiation facility. The first medical irradiation for BNCT was carried out on 25th October 1999. The patient was treated by Tsukuba University group using thermal neutron beam included epi-thermal neutrons. (author)
Contourlet Filter Design Based on Chebyshev Best Uniform Approximation
Ming Hou
2010-01-01
Full Text Available The contourlet transform can deal effectively with images which have directional information such as contour and texture. In contrast to wavelets for which there exists many good filters, the contourlet filter design for image processing applications is still an ongoing work. Therefore, this paper presents an approach for designing the contourlet filter based on the Chebyshev best uniform approximation for achieving an efficient image denoising applications using hidden Markov tree models in the contourlet domain. Here, we design both the optimal 9/7 wavelet filter banks with rational coefficients and new pkva 12 filter. In this paper, the Laplacian pyramid followed by the direction filter banks decomposition in the contourlet transform using the two filter banks above and the image denoising applications in the contourlet hidden Markov tree model are implemented, respectively. The experimental results show that the denoising performance of the test image Zelda in terms of peak signal-to-noise ratio is improved by 0.33 dB than using CDF 9/7 filter banks with irrational coefficients on the JPEG2000 standard and standard pkva 12 filter, and visual effects are as good as compared with the research results of Duncan D.-Y. Po and Minh N. Do.
Contourlet Filter Design Based on Chebyshev Best Uniform Approximation
Fang Xiaofeng
2010-01-01
Full Text Available Abstract The contourlet transform can deal effectively with images which have directional information such as contour and texture. In contrast to wavelets for which there exists many good filters, the contourlet filter design for image processing applications is still an ongoing work. Therefore, this paper presents an approach for designing the contourlet filter based on the Chebyshev best uniform approximation for achieving an efficient image denoising applications using hidden Markov tree models in the contourlet domain. Here, we design both the optimal 9/7 wavelet filter banks with rational coefficients and new pkva 12 filter. In this paper, the Laplacian pyramid followed by the direction filter banks decomposition in the contourlet transform using the two filter banks above and the image denoising applications in the contourlet hidden Markov tree model are implemented, respectively. The experimental results show that the denoising performance of the test image Zelda in terms of peak signal-to-noise ratio is improved by 0.33 dB than using CDF 9/7 filter banks with irrational coefficients on the JPEG2000 standard and standard pkva 12 filter, and visual effects are as good as compared with the research results of Duncan D.-Y. Po and Minh N. Do.
Filter-and-Forward Transparent Relay Design for OFDM Systems
Kim, Donggun; Sung, Youngchul
2012-01-01
In this paper, the filter-and-forward (FF) relay design for orthogonal frequency-division multiplexing (OFDM) transmission systems is considered to improve the system performance over simple amplify-and-forward (AF) relaying. Unlike conventional OFDM relays performing OFDM demodulation and remodulating, to reduce processing complexity, the proposed FF relay directly filters the incoming signal with a finite impulse response (FIR) and forwards the filtered signal to the destination. Two design criteria are considered to optimize the relay filter for given source power allocation. One is to minimize the relay transmit power subject to per-subcarrier signal-to-noise ratio (SNR) constraints and the other is to maximize the worst subcarrier channel SNR subject to the total relay transmit power constraint. It is shown that the two problems reduce to semi-definite programming (SDP) problems. Furthermore, the problem of joint source power allocation and relay filter design is considered for the second criterion, and ...
Digital IIR Filter Design using Real Coded Genetic Algorithm
Ranjit Kaur
2013-06-01
Full Text Available The paper develops a technique for the robust and stable design of digital infinite impulse response (IIR filters. As the error surface of IIR filters is generally multi-modal, global optimization techniques are required to design efficient digital IIR filter in order to avoid local minima. In this paper a real-coded genetic algorithm (RCGA with arithmetic-average-bound-blend crossover and wavelet mutation is applied to design the digital IIR filter. A multicriterion optimization is employed as the design criterion to obtain the optimal stable IIR filter that satisfies the different performance requirements like minimizing the Lp-norm approximation error and minimizing the ripple magnitude. The proposed real-coded genetic algorithm is effectively applied to solve the multicriterion, multiparameter optimization problems of low-pass, high-pass, band-pass, and band-stop digital filters design. The computational experiments show that the proposed method is superior or atleast comparable to other algorithms and can be efficiently used for higher order filter design.
Modern analog filter analysis and design a practical approach
Raut, R
2011-01-01
Starting from the fundamentals, the present book describes methods of designing analog electronic filters and illustrates these methods by providing numerical and circuit simulation programs. The subject matters comprise many concepts and techniques that are not available in other text books on the market. To name a few - principle of transposition and its application in directly realizing current mode filters from well known voltage mode filters; an insight into the technological aspect of integrated circuit components used to implement an integrated circuit filter; a careful blending of basi
Rirang Uranium Ore Processing System Design Horizontal Belt Filter
Horizontal belt filter one of the solid-liquid separation process equipment. The design of Horizontal Belt Filter have been conducted for capacity of 250 g/minute. The result obtained was filtering velocity of 0,4 g/cm2 minute. The linear belt speeds 100 cm/minute. The length and width of the belt 125 cm also the filtering cycle of 1,25 minute. The operation of that equipment give result about 77,9 - 79,1% of product cake
Design and Development of Low Pass Filter at 60 GHz
Sanjeev Kumar Shah
2013-07-01
Full Text Available This paper describes the design and development of low pass filter (LPF at 60 GHz. The present design uses stepped impedance method in suspended strip line. The design is modeled and optimized using CST (Computer Simulation Technology microwave studio. The design of a filter types that Tchebysheve 0.1 dB ripple in the passband with the standard bandwidth of 2% and 30 dB attenuation at 94 GHz. The 60 GHz low pass filter exhibits an insertion loss of 1 dB with 3 dB relative bandwidth at a cut-off frequency of 60 GHz and the return loss is better than -18 dB at a cut-off frequency. The designed and fabricated low pass filter shows the good performance for planar integrated millimeter-wave circuits
Chirped-cavity dispersion-compensation filter design
Li, Ya-Ping; Chen, Sheng-Hui; Lee, Cheng-Chung
2006-03-01
A new basic structure of a dispersive-compensation filter, called a chirped-cavity dispersion-compensator (CCDC) filter, was designed to offer the advantages of small ripples in both reflectance and group-delay dispersion (GDD). This filter provides a high dispersion compensation, like the Gires-Tournois interferometer (GTI) filter, and a wide working bandwidth, like the chirped mirror (CM). The structure of the CCDC is a cavity-type Fabry-Perot filter with a spacer layer (2 mH or 2 mL) and a chirped high reflector. The CCDC filter can provide a negative GDD of -50 fs2 over a bandwidth of 56 THz with half the optical thickness of the CM or the GTI.
Accelerator technology and SPECT developments for BNCT
Accelerator-Based BNCT (AB-BNCT) is establishing itself worldwide as the future modality to start the phase of in-hospital facilities. There are projects in Russia, UK, Italy, Japan, Israel, and Argentina to develop AB-BNCT around different types of accelerators. They will be briefly mentioned. In particular, the present status and recent progress of the Argentine project will be presented. The topics will cover: high power ion sources, power and voltage generation systems for a Tandem- Electrostatic Quadrupole (TES Q) accelerator, acceleration tubes, transport of intense beams, beam diagnostics, control systems, high power targets, the 9Be(d,n) reaction as a possible neutron source, Beam Shaping Assemblies (BSA.s), treatment room design, treatment planning assessment of clinical cases, etc. A complete test stand has been built and commissioned for intense proton beam production and characterization. Beams of 10 to 30 m A have been produced and transported during variable periods of operation by means of a pre accelerator and an electrostatic quadrupole doublet to a suppressed Faraday cup. The beam diagnostics has been performed through the observation with digital cameras of induced fluorescence in the residual gas. A 200 kV TES Q accelerator prototype has been constructed and tested and a 600 keV prototype is under construction. Self consistent space charge beam transport simulations have been performed and compared with experimental results. In addition to the traditional 7Li(p,n)7Be reaction, 9Be(d,n)10B using a thin Be target has been thoroughly studied as a candidate for a possible neutron source for deep seated tumors, showing a satisfactory performance. BSA.s and production targets and a treatment room complying with regulations have also been designed. Realistic clinical treatment planning cases for AB-BNCT have been studied showing very good results. Finally we will present advances in the development of a Single Photon Emission Computed Tomography (SPECT
Summary of recent BNCT Polish programme and future plans.
Gryziński, M A; Maciak, M; Wielgosz, M
2015-12-01
In this work we present Polish achievements on the ground of BNCT research. Starting from preliminary built therapeutic stand at MARIA reactor going through designing of unique detectors for in-phantom and in-beam measurements for mixed radiation fields and finally coming to boron carriers synthesizing and examination in cellular and animal models. Now it is planned to restart research on boron compounds in specially designed BIMA line, to set up epithermal neutron irradiation facility for BNCT research and education and to improve recombination detectors for neutron beams characterisation. PMID:26293009
Mechanical design of the TripleWave debris filter
This paper presents the design of the TripleWave debris filter. The function of the debris filter is to reduce the amount of debris that can enter the active fuel region and thereby reduce the risk for damage of the fuel cladding by fretting. The design is aimed at catching long and thin debris as this has proved to constitute the largest fretting risk. The trapping efficiency tests demonstrate that the TripleWave debris filter reduces the risk for harmful debris to enter the fuel assembly significantly compared with the current filter design. Fuel assemblies equipped with the TripleWave filter are thermal hydraulic compatible with assemblies equipped with current filter design even with large amounts of debris trapped in the filter. A full-scale endurance test showed no signs of wear between the components in the lower part of the test assembly. The design is robust and redundant, it is subjected to very small stresses and a very well known and proven material is used and reactor operation without mechanical problems can be expected. (author)
Software Engineering-Based Design for a Bayesian Spam Filter
Mumtaz Mohammed Ali AL-Mukhtar
2010-01-01
Full Text Available The rapid spread and the easy availability of a free e-mail service have made it the medium of choice for the sending of unsolicited advertising and bulk e-mail in general. These messages, known as junk e-mail or spam mail, are an increasing problem to both Internet users and Internet service providers (ISPs. The research resolves one aspect of the spam problem by developing an appropriate filter for the e-mail client. The proposed filter is a combination of three forms of filters: Whitelist, Blacklist, and a Bayesian filter. Whitelist-based filter only accepts e-mails from known addresses. Blacklist filter blocks e-mails from addresses known to send out spam. Bayesian content-based filter makes estimations of spam probability based on the text and filters messages based on a pre-selected threshold.The Bayesian filter is selected to be the main filter. The Bayesian filter is manually trained on a set of gathered e-mails; some of them are spam and the others are legitimate based on the contents of an e-mail. Thereafter the classification phase has been implemented for new entered e-mails. All the required databases are constructed in form of tables stored in the Structured Query Language (SQL server. The filter at the client side can transparently access the database in order to carry on the intended filtering. The proposed system (e-mail client interface and the filters can manage messages written in both Arabic and English languages which is crucial for the users in our region.Software engineering principals are implemented throughout the design process to make the system less vulnerable to faults and easily maintained. The design steps have followed the Waterfall-model using the ASCENT software. A user-friendly interface has been developed to access the features of the spam filter at the client side. Visual Basic version 6 has been used to develop the system. As well, the SQL server has been implemented to build and process the database
Design and Efficient Implementation of Oversampled GDFT Filter Banks for Subband Adaptive Filtering
Weiss, S; Harteneck, M; Stewart, R W
1998-01-01
This paper introduces a polyphase implementation and design of an oversampled K-channel generalized DFT (GDFT) filter bank, which can be employed for subband adaptive filtering, and therefore is required to have a low aliasing level in the subband signals. A polyphase structure is derived which can be factorized into a real valued polyphase network and a GDFT modulation. For the latter, an FFT realization may be used, yielding a highly efficient polyphase implementation for arbitrary integer ...
An in-phantom comparison of neutron fields for BNCT
Previously, the authors have developed the in-phantom neutron field assessment parameters T and D (Tumor) for the evaluation of epithermal neutron fields for use in BNCT. These parameters are based on an energy-spectrum-dependent neutron normal-tissue RBE and the treatment planning methodology of Gahbauer and his co-workers, which includes the effects of dose fractionation. In this paper, these neutron field assessment parameters were applied to The Ohio State University (OSU) design of an Accelerator Based Neutron Source (ABNS) (hereafter called the OSU-ABNS) and the Brookhaven Medical Research Reactor (BMRR) epithermal neutron beam (hereafter called the BMRR-ENB), in order to judge the suitability of the OSU-ABNS for BNCT. The BMRR-ENB was chosen as the basis for comparison because it is presently being used in human clinical trials of BNCT and because it is the standard to which other neutron beams are most often compared
INEEL BNCT Research Program Annual Report, CY-2000
Venhuizen, James Robert
2001-03-01
This report is a summary of the activities conducted in conjunction with the Idaho National Engineering and Environmental Laboratory (INEEL) Boron Neutron Capture Therapy (BNCT) Research Program for calendar year 2000. Applications of supportive research and development, as well as technology deployment in the fields of chemistry, radiation physics and dosimetry, neutron source design and demonstration, and support the Department of Energy’s (DOE) National BNCT Program goals are the goals of this Program. Contributions from the individual contributors about their projects are included, specifically described are the following, chemistry: analysis of biological samples and an infrared blood-boron analyzer, and physics: progress in the patient treatment planning software, measurement of neutron spectra for the Argentina RA-6 reactor, and recalculation of the Finnish research reactor FiR 1 neutron spectra, BNCT accelerator technology, and modification to the research reactor at Washington State University for an epithermal-neutron beam.
A comparison of methods for DPLL loop filter design
Aguirre, S.; Hurd, W. J.; Kumar, R.; Statman, J.
1986-01-01
Four design methodologies for loop filters for a class of digital phase-locked loops (DPLLs) are presented. The first design maps an optimum analog filter into the digital domain; the second approach designs a filter that minimizes in discrete time weighted combination of the variance of the phase error due to noise and the sum square of the deterministic phase error component; the third method uses Kalman filter estimation theory to design a filter composed of a least squares fading memory estimator and a predictor. The last design relies on classical theory, including rules for the design of compensators. Linear analysis is used throughout the article to compare different designs, and includes stability, steady state performance and transient behavior of the loops. Design methodology is not critical when the loop update rate can be made high relative to loop bandwidth, as the performance approaches that of continuous time. For low update rates, however, the miminization method is significantly superior to the other methods.
Quality assurance of BNCT dosimetry
The Phase I clinical trials for boron neutron capture therapy (BNCT) started in May 1999 in Otaniemi, Espoo. For BNCT no uniform international guidance for the quality assurance of dosimetry exists, so far. Because of the complex dose distribution with several different dose components, the international recommendations on conventional radiotherapy dosimetry are not applicable in every part. Therefore, special guidance specifically for BNCT is needed. To obtain such guidelines a European collaboration project has been defined. The aim of the project is a generally accepted Code of Practice for use by all European BNCT centres. This code will introduce the traceability of the dosimetric methods to the international measurement system. It will also ensure the comparability of the results in various BNCT beams and form the basis for the comparison of the treatment results with the conventional radiotherapy or other treatment modalities. The quality assurance of the dosimetry in BNCT in Finland covers each step of the BNCT treatment, which include dose planning imaging, dose planning, boron infusion, boron kinetics, patient positioning, monitoring of the treatment beam, characterising the radiation spectrum, calibration of the beam model and the dosimetric measurements both in patients (in viva measurements) and in various phantoms. The dose planning images are obtained using a MR scanner with MRI sensitive markers and the dose distribution is computed with a dose planning software BNCTRtpe. The program and the treatment beam (DORT) model used have been verified with measurements and validated with MCNP calculations in phantom. Dosimetric intercomparison has been done with the Brookhaven BNCT beam (BMRR). Before every patient irradiation the relationship between the beam monitor pulse rate and neutron fluence rate in the beam is checked by activation measurements. Kinetic models used to estimate the time-behavior of the blood boron concentration have been verified
A Transmission-Filter Coronagraph: Design and Test
Ren, Deqing; Zhu, Yongtian
2015-01-01
We propose a transmission-filter coronagraph for direct imaging of Jupiter-like exoplanets with ground-based telescopes. The coronagraph is based on a transmission filter that consists of finite number of transmission steps. A discrete optimization algorithm is proposed for the design of the transmission filter that is optimized for ground-based telescopes with central obstructions and spider structures.We discussed the algorithm that is applied for our coronagraph design. To demonstrate the performance of the coronagraph, a filter was manufactured and laboratory tests were conducted. The test results show that the coronagraph can achieve a high contrast of 10 to -6.5 at an inner working angle of 5{\\lambda}/D, which indicates that our coronagraph can be immediately used for the direct imaging of Jupiter-like exoplanets with ground-based telescopes.
Design and Analysis of Parallel-Coupled Line Bandpass Filter
Talib Mahmood Ali
2013-01-01
A compact microwave parallel coupled line resonator seventh order bandpass filter (BPF) is presented in this paper, consist a 8-parallel coupled line pairs designed for a maximally flat response or Butterworth response at a center frequency of 2.44175 GHz and with a fractional bandwidth, Δ= 0.035. The filter was implemented in a microstrip platform with a permittivity of the substrate Er=4.4 and a substrate height h=1.5mm. The physical parameters of the parallel coupled line filter sections w...
Broadband notch filter design for millimeter-wave plasma diagnostics
Furtula, Vedran; Michelsen, Poul; Leipold, Frank;
2010-01-01
Notch filters are integrated in plasma diagnostic systems to protect millimeter-wave receivers from intensive stray radiation. Here we present a design of a notch filter with a center frequency of 140 GHz, a rejection bandwidth of ∼ 900 MHz, and a typical insertion loss below 2 dB in the passband...... in the cylindrical cavities is the fundamental TE11. The performance of the constructed filter is measured using a vector network analyzer monitoring a total bandwidth of 30 GHz. We compare the measurements with numerical simulations. © 2010 EURATOM...
An Ant Colony Optimization Algorithm for Microwave Corrugated Filters Design
Ivan A. Mantilla-Gaviria
2013-01-01
Full Text Available A practical and useful application of the Ant Colony Optimization (ACO method for microwave corrugated filter design is shown. The classical, general purpose ACO method is adapted to deal with the microwave filter design problem. The design strategy used in this paper is an iterative procedure based on the use of an optimization method along with an electromagnetic simulator. The designs of high-pass and band-pass microwave rectangular waveguide filters working in the C-band and X-band, respectively, for communication applications, are shown. The average convergence performance of the ACO method is characterized by means of Monte Carlo simulations and compared with that obtained with the well-known Genetic Algorithm (GA. The overall performance, for the simulations presented herein, of the ACO is found to be better than that of the GA.
Mandal, Subhra [Department of Tumor Immunology, Radboud University Nijmegen Medical Centre (Netherlands); Bakeine, Gerald J., E-mail: Jamesbakeine1@yahoo.com [Department of Internal Medicine and Therapeutics-Section of Clinical Toxicology, University of Pavia, Piazza Botta 10, 27100 Pavia (Italy); Krol, Silke [Institute of Neurology, Fondazione IRCCS Carlo Besta, Milan (Italy); Ferrari, Cinzia; Clerici, Anna M.; Zonta, Cecilia; Cansolino, Laura [Department of Surgery, Laboratory of Experimental Surgery, University of Pavia (Italy); Ballarini, Francesca [Department of Nuclear and Theoretical Physics, University of Pavia (Italy); Bortolussi, Silva [Department of Nuclear and Theoretical Physics, University of Pavia (Italy)] [National Institute of Nuclear Physics (INFN), Section of Pavia (Italy); Stella, Subrina; Protti, Nicoletta [Department of Nuclear and Theoretical Physics, University of Pavia (Italy); Bruschi, Piero [National Institute of Nuclear Physics (INFN), Section of Pavia (Italy); Altieri, Saverio [Department of Nuclear and Theoretical Physics, University of Pavia (Italy)] [National Institute of Nuclear Physics (INFN), Section of Pavia (Italy)
2011-12-15
The aim of this study is to optimize targeted boron delivery to cancer cells and its tracking down to the cellular level. To this end, we describe the design and synthesis of novel nanovectors that double as targeted boron delivery agents and fluorescent imaging probes. Gold nanoparticles were coated with multilayers of polyelectrolytes functionalized with the fluorescent dye (FITC), boronophenylalanine and folic acid. In vitro confocal fluorescence microscopy demonstrated significant uptake of the nanoparticles in cancer cells that are known to overexpress folate receptors. - Highlights: Black-Right-Pointing-Pointer Synthesis of multi-labeled gold nanoparticles for selective boron delivery to tumor cells. Black-Right-Pointing-Pointer Tumor selectivity is achieved through folic acid receptor targeting. Black-Right-Pointing-Pointer Optical fluorescent microscopy allows tracking of cellular uptake of the gold nanoparticle. Black-Right-Pointing-Pointer In vitro tests demonstrate selective nanoparticle up in folate receptor positive tumor cells.
The aim of this study is to optimize targeted boron delivery to cancer cells and its tracking down to the cellular level. To this end, we describe the design and synthesis of novel nanovectors that double as targeted boron delivery agents and fluorescent imaging probes. Gold nanoparticles were coated with multilayers of polyelectrolytes functionalized with the fluorescent dye (FITC), boronophenylalanine and folic acid. In vitro confocal fluorescence microscopy demonstrated significant uptake of the nanoparticles in cancer cells that are known to overexpress folate receptors. - Highlights: ►Synthesis of multi-labeled gold nanoparticles for selective boron delivery to tumor cells. ► Tumor selectivity is achieved through folic acid receptor targeting. ► Optical fluorescent microscopy allows tracking of cellular uptake of the gold nanoparticle. ► In vitro tests demonstrate selective nanoparticle up in folate receptor positive tumor cells.
Novel design method for generalized lattice filters
Agger, Søren; Povlsen, Jørn Hedegaard; Leick, Lasse; Zauner, Dan Anker
2003-01-01
A new design method for wide-band gain equalizers using cascaded MZI's is proposed. The method achieves a given accuracy with fewer stages than previously described methods. Furthermore, the method is capable of minimizing PDL.
Novel design method for generalized lattice filters
Agger, Søren; Povlsen, Jørn Hedegaard; Leick, Lasse; Zauner, Dan Anker
A new design method for wide-band gain equalizers using cascaded MZI's is proposed. The method achieves a given accuracy with fewer stages than previously described methods. Furthermore, the method is capable of minimizing PDL.......A new design method for wide-band gain equalizers using cascaded MZI's is proposed. The method achieves a given accuracy with fewer stages than previously described methods. Furthermore, the method is capable of minimizing PDL....
A dog was diagnosed with osteosarcoma (8x6x5cm) in the right wing of ilium by radiography, radionuclide scintigraphy and histological study of biopsy material. The treatment plan was as follows: γ-therapy in combination with chemotherapy; prevention of hematogenous pulmonary metastases by the transfusion of 130 ml of allogenic marrow from a healthy donor; administration of 11.4g 10B-boronphenylalanine into the right iliac artery; resection of the right iliac wing with the osteosarcoma lesion; neutron irradiation (MEPhI Reactor) of the bone fragment (dose on healthy osteocytes - 15±4 Gy (W), on tumor - 50±9 Gy (W); reimplantation and fixation of the fragment; three courses of adjuvant chemotherapy. The doses were determined in full-scale calculations of the reactor radiation fields with a model of the bone under the code RADUGA. The 10B concentration (μg/g) in the bone was: normal tissue - 9±3, tumor - 28±5. In 24 hours post operation the dog was able to walk using the treated limb, and 6 months later it moved freely. The patient has been under observation for 30 months. The results of the research demonstrate complete cure. The use of similar treatment plans improves the therapeutic efficiency of BNCT. (author)
FULL SCALE REGENERABLE HEPA FILTER DESIGN USING SINTERED METAL FILTER ELEMENTS
A Department of Energy funded contract involved the development of porous metal as a HEPA filter, and the subsequent design of a full-scale regenerable HEPA filtration system (RHFS). This RHFS could replace the glass fiber HEPA filters currently being used on the high level waste (HLW) tank ventilation system with a system that would be moisture tolerant, durable, and cleanable in place. The origins of the contract are a 1996 investigation at the Savannah River Technology Center (SRTC) regarding the use of porous metal as a HEPA filter material. This contract was divided into Phases I, IIA and IIB. Phase I of the contract evaluated simple filter cylinders in a simulated High Level Waste (HLW) environment and the ability to clean and regenerate the filter media after fouling. Upon the successful completion of Phase I, Phase IIA was conducted, which included lab scale prototype testing and design of a full-scale system. The work completed under Phase IIA included development of a full-scale system design, development of a filter media meeting the HEPA filtration efficiency that would also be regenerable using prescribed cleaning procedures, and the testing of a single element system prototype at Savannah River. All contract objectives were met. The filter media selected was a nickel material already under development at Mott, which met the HEPA filtration efficiency standard. The Mott nickel media met and exceeded the HEPA requirement, providing 99.99% removal against a requirement of 99.97%. Double open-ended elements of this media were provided to the Savannah River Test Center for HLW simulation testing in the single element prototype filter. These elements performed well and further demonstrated the practicality of a metallic media regenerable HEPA filter system. An evaluation of the manufacturing method on many elements demonstrated the reproducibility to meet the HEPA filtration requirement. The full-scale design of the Mott RHFS incorporated several important
FULL SCALE REGENERABLE HEPA FILTER DESIGN USING SINTERED METAL FILTER ELEMENTS
Gil Ramos; Kenneth Rubow; Ronald Sekellick
2002-11-27
A Department of Energy funded contract involved the development of porous metal as a HEPA filter, and the subsequent design of a full-scale regenerable HEPA filtration system (RHFS). This RHFS could replace the glass fiber HEPA filters currently being used on the high level waste (HLW) tank ventilation system with a system that would be moisture tolerant, durable, and cleanable in place. The origins of the contract are a 1996 investigation at the Savannah River Technology Center (SRTC) regarding the use of porous metal as a HEPA filter material. This contract was divided into Phases I, IIA and IIB. Phase I of the contract evaluated simple filter cylinders in a simulated High Level Waste (HLW) environment and the ability to clean and regenerate the filter media after fouling. Upon the successful completion of Phase I, Phase IIA was conducted, which included lab scale prototype testing and design of a full-scale system. The work completed under Phase IIA included development of a full-scale system design, development of a filter media meeting the HEPA filtration efficiency that would also be regenerable using prescribed cleaning procedures, and the testing of a single element system prototype at Savannah River. All contract objectives were met. The filter media selected was a nickel material already under development at Mott, which met the HEPA filtration efficiency standard. The Mott nickel media met and exceeded the HEPA requirement, providing 99.99% removal against a requirement of 99.97%. Double open-ended elements of this media were provided to the Savannah River Test Center for HLW simulation testing in the single element prototype filter. These elements performed well and further demonstrated the practicality of a metallic media regenerable HEPA filter system. An evaluation of the manufacturing method on many elements demonstrated the reproducibility to meet the HEPA filtration requirement. The full-scale design of the Mott RHFS incorporated several important
Our research group at the Radiation Pathology Division of the Department of Radiobiology (National Atomic Energy Commission) has previously demonstrated the therapeutic efficacy of different BNCT protocols to treat oral cancer in an experimental hamster cheek pouch model. In particular, to perform studies in this experimental model at the thermal facility constructed at RA-3, we designed and constructed a shielding device for thermal neutrons, to be able to expose the cheek pouch while minimizing the dose to the rest of the body. This device allowed for the irradiation of one animal at a time. Given the usage rate of the device, the aim of the present study was to design and construct an optimized version of the existing shielding device that would allow for the simultaneous irradiation of 2 animals at the thermal facility of RA-3. Taking into account the characteristics of the neutron source and preliminary biological assays, we designed the shielding device for the body of the animal, i.e. a rectangular shaped box with double acrylic walls. The space between the walls contains a continuous filling of 6Li2CO3 (95% enriched in 6Li), approximately 6 mm thick. Two small windows interrupt the shield at one end of the box through which the right pouch of each hamster is everted out onto an external acrylic shelf for exposure to the neutron flux. The characterization of the shielding device showed that the neutron flux was equivalent at both irradiation positions confirming that we were able to design and construct a new shielding device that allows for the irradiation of 2 animals at the same time at the thermal facility of RA-3. This new version of the shielding device will reduce the number of interventions of the reactor operators, reducing occupational exposure to radiation and will make the procedure more efficient for researchers. In addition, we addressed the generation of tritium as a product of the capture reaction in lithium. It was considered as a potential
Principles and Design Rationale of Composition Filters
Bergmans, Lodewijk; Aksit, Mehmet; Filman, Robert E.; Elrad, Tzilla; Clarke, Siobhán; Akşit, Mehmet
2004-01-01
A wide range of aspect-oriented programming languages has appeared in the past years [7]. Current research on future generation AOP languages is addressing issues like flexibility, expressive power and safety. We think that it is important to understand the motivations and design decisions of the fi
Design and control of hybrid active power filters
Lam, Chi-Seng
2014-01-01
Design and Control of Hybrid Active Power Filters presents an overview of the current quality problems and their compensators. To get a balance between the system cost and performance, hybrid active power filters (HAPFs) are valuable. The book presents the coverage of resonance phenomena prevention capability, filtering performance and system robustness analysis of HAPF; nonlinear inverter current slope characteristics and their linear operation region requirement analysis of the hysteresis PWM for the HAPF; minimum inverter capacity design procedure of HAPF, adaptive dc-link voltage controller for the HAPF and the real design example of a 220V 10kVA HAPF, in which the system performance analysis method, minimum dc voltage deduction concept and adaptive dc voltage idea can be further extended into the other active compensators, such as APF, static synchronous compensator STATCOM, etc. This book will benefit researchers, graduate students, and electrical power engineers in the field of power-quality compensati...
Ken Smigielski; Farhang Akbar-Khanzadeh
2009-01-01
An air filter is a significant element of any mechanical ventilation system. However, the importance and performance evaluation of air filters have not been well publicized and related scientific reports are scarce. In this study, a transportable, off-line, air filter-testing unit (the Unit) was designed and utilized to simulate the filter housing of a mechanical ventilation system. The Unit was designed, assembled, and operated in a laboratory. To demonstrate the applications of the Unit, a ...
UWB microstrip filter design using a time-domain technique
Tekin, İbrahim; TEKIN Ibrahim
2005-01-01
A time-domain technique is proposed for ultra-wideband (UWB) microstrip-filter design. The design technique uses the reflection coefficient (S11) specified in the frequency domain. When the frequency response of the UWB filter is given, the response will be approximated by a series of UWB pulses in the time domain. The UWB pulses are Gaussian pulses of the same bandwidth with different time delays. The method tries to duplicate the reflection scenario in the time domain for very narrow Gaussi...
NEW DESIGN OF ROBUST OPTIMAL ARBITRARY TIME-DELAY FILTER
WANG Xiaojun; SHAO Huihe
2007-01-01
Zero placement method in the frequency domain is utilized to design robust multi-hump EI optimal arbitrary time-delay filter (OATF) by placing two or more filter zeros near the system poles. A total insensitive OATF can be also achieved if the problem of insensitivity to damping errors is considered. This design strategy is easier to derive and implement. Applications in the anti-swing control of overhead cranes verify the fine performance of this strategy. A better suppression of the load vibrations is obtained using the proposed new OATF, which is more robust to the variation of the cable length.
Designing Asynchronous Circuits for Low Power: An IFIR Filter
Nielsen, Lars Skovby; Sparsø, Jens
1999-01-01
This paper addresses the design of asynchronous circuits for low power through an example: a filter bank for a digital hearing aid. The asynchronous design re-implements an existing synchronous circuit which is used in a commercial product. For comparison, both designs have been fabricated in the...... by numerically small samples). Apart from the improved RAM design, these measures are only viable in an asynchronous design. The principles and techniques explained in this paper are of a general nature, and they apply to the design of asynchronous low-power digital signal-processing circuits in a...
Shailendra Singh Ojha
2013-04-01
Full Text Available The purpose of this paper is to design a microstrip patch antenna with low pass filter for efficient rectenna design this structure having the property of rejecting higher harmonics than 2GHz. As the design frequency is 2GHz.in first step we design a patch antenna in second step we design patch antenna with low pass filter and combine these two. The IE3D software is used for the simulation of this structure.
Shailendra Singh Ojha; P. K. Singhal; Anshul agarawal; Akhilesh Gupta
2013-01-01
The purpose of this paper is to design a microstrip patch antenna with low pass filter for efficient rectenna design this structure having the property of rejecting higher harmonics than 2GHz. As the design frequency is 2GHz.in first step we design a patch antenna in second step we design patch antenna with low pass filter and combine these two. The IE3D software is used for the simulation of this structure.
Design of Microstrip UWB bandpass Filter using Multiple Mode Resonator
Vinay Kumar Sharma
2014-10-01
Full Text Available In this letter, we present a design of microstrip ultrawideband (UWB bandpass filter (BPF for the use in UWB wireless communication application set by Federal Communications Commission (FCC. The UWB filter is realized with a Basic MMR (Multiple Mode Resonators structure feed by interdigital coupled lines for achieving higher degree of coupling. The structure is optimized for high selectivity, inband and stopband performance. Finally for fabrication of this structure Rogers RT5880 substrate of thickness 0.4mm with Dielectric constant 2.2 is used. The electromagnetic simulation software, Computer Simulation Technology Microwave Studio (CST MWS is used for the simulation and analysis of the designed structure. The comparison between simulated and fabricated measured result shows good agreement. The insertion loss of proposed filter is greater then 0.2 dB at 6.8 GHz and very flat over whole pass band also returns loss is less then -12db.
Design of Low Pass Digital FIR Filter Using Cuckoo Search Algorithm
Taranjit Singh; Harvinder Singh Josan
2014-01-01
This paper presents a novel approach of designing linear phase FIR low pass filter using cuckoo Search Algorithm (CSA). FIR filter design is a multi-modal optimization problem. The conventional optimization techniques are not efficient for digital filter design. An iterative method is introduced to find the best solution of FIR filter design problem.Flat passband and high stopband attenuation are the major characteristics required in FIR filter design. To achieve these charact...
Design and Analysis of Parallel-Coupled Line Bandpass Filter
Talib Mahmood Ali
2013-09-01
Full Text Available A compact microwave parallel coupled line resonator seventh order bandpass filter (BPF is presented in this paper, consist a 8-parallel coupled line pairs designed for a maximally flat response or Butterworth response at a center frequency of 2.44175 GHz and with a fractional bandwidth, Δ= 0.035. The filter was implemented in a microstrip platform with a permittivity of the substrate Er=4.4 and a substrate height h=1.5mm. The physical parameters of the parallel coupled line filter sections were optimized using the Microwave Office software to provide the closest values of the bandpass filter prototype values and electrical lengths for a given set of filter specifications. The simulation of direct calculation, show the attenuation S11 response was observed at 2.44175 GHz with a value of -25 dB and the corresponding Insertion Loss S21 is - 1.8dB while the optimized design S11 response at the centre frequency with a value of -113 dB and the corresponding Insertion Loss S21 is -2.2dB.
Gravitation search algorithm: Application to the optimal IIR filter design
Suman Kumar Saha
2014-01-01
Full Text Available This paper presents a global heuristic search optimization technique known as Gravitation Search Algorithm (GSA for the design of 8th order Infinite Impulse Response (IIR, low pass (LP, high pass (HP, band pass (BP and band stop (BS filters considering various non-linear characteristics of the filter design problems. This paper also adopts a novel fitness function in order to improve the stop band attenuation to a great extent. In GSA, law of gravity and mass interactions among different particles are adopted for handling the non-linear IIR filter design optimization problem. In this optimization technique, searcher agents are the collection of masses and interactions among them are governed by the Newtonian gravity and the laws of motion. The performances of the GSA based IIR filter designs have proven to be superior as compared to those obtained by real coded genetic algorithm (RGA and standard Particle Swarm Optimization (PSO. Extensive simulation results affirm that the proposed approach using GSA outperforms over its counterparts not only in terms of quality output, i.e., sharpness at cut-off, smaller pass band ripple, higher stop band attenuation, but also the fastest convergence speed with assured stability.
105 GHz Notch Filter Design for Collective Thomson Scattering
Furtula, Vedran; Michelsen, Poul; Leipold, Frank; Johansen, T.; Korsholm, Søren Bang; Meo, Fernando; Moseev, Dmitry; Nielsen, Stefan Kragh; Salewski, Mirko; Stejner Pedersen, Morten
2011-01-01
A millimeter-wave notch filter with 105-GHz center frequency, >20-GHz passband coverage, and 1-GHz rejection bandwidth has been constructed. The design is based on a fundamental rectangular waveguide with cylindrical cavities coupled by narrow iris gaps, i.e., small elongated holes of negligible...
Design and analysis of electromagnetic interference filters and shields
McDowell, Andrew Joel
Electromagnetic interference (EMI) is a problem of rising prevalence as electronic devices become increasingly ubiquitous. EMI filters are low pass filters intended to prevent the conducted electric currents and radiated electromagnetic fields of a device from interfering with the proper operation of other devices. Shielding is a method, often complementary to filtering, that typically involves enclosing a device in a conducting box in order to prevent radiated EMI. This dissertation includes three chapters related to the use of filtering and shielding for preventing electromagnetic interference. The first chapter deals with improving the high frequency EMI filtering performance of surface mount capacitors on printed circuit boards (PCBs). At high frequencies, the impedance of a capacitor is dominated by a parasitic inductance, thus leading to poor high frequency filtering performance. Other researchers have introduced the concept of parasitic inductance cancellation and have applied this concept to improving the filtering performance of volumetrically large capacitors at frequencies up to 100 MHz. The work in this chapter applies the concept of parasitic inductance cancellation to much smaller surface mount capacitors at frequencies up to several gigahertz. The second chapter introduces a much more compact design for applying parasitic inductance cancellation to surface mount capacitors that uses inductive coupling between via pairs as well as coplanar traces. This new design is suited for PCBs having three or more layers including solid ground and/or power plane(s). This design is demonstrated to be considerably more effective in filtering high frequency noise due to crosstalk than a comparable conventional shunt capacitor filter configuration. Finally, chapter 3 presents a detailed analysis of the methods that are used to decompose the measure of plane wave shielding effectiveness into measures of absorption and reflection. Textbooks on electromagnetic
Sagar R. Patil; Prof. Sachin V. Lomte
2015-01-01
In automobile vehicles mostly plastic molded panel filters used for the purpose of engine air filtration. Fibrous structured cellulose media were being used with different permeability’s according to requirement of rated air flow rate required for the engine. To optimize the filter pleat design of automotive panel air filter, it is important to study correlation of pressure drop, dust holding capacity & efficiency. The main role of a filter is to provide least pressure drop with h...
Three different criteria for the design of two-dimensional zero phase FIR digital filters
Gislason, E.; Johansen, M.; Conradsen, Knut;
1993-01-01
An error criterion for the design of FIR filters is proposed. Filters with relatively many free filter coefficients are designed using the Chebyshev, the weighted-least-squares (WLS), and a new partitioned minimax error criterion, and the performance of the filters is compared. A general and fast...... technique for the WLS design is also presented.>...
An Applied Method for Designing Maximally Decimating Non-uniform Filter Banks
无
2003-01-01
Assembling individual line phase filters to form a multi-channel filter bank allows the synthesis filter to be similar to corresponding analysis filters, and the design calculation can be simple. The appropriate relations between synthesis filters and analysis filters eliminate most aliasing resulting from decimation in non-uniform maximally decimating filter banks, and LS algorithm and Remez algorithm are used to optimize the composite character. This design method can achieve approximate Perfect-Reconstruction. An example is given in which the general parameter filters with approximate line phase are used as units of a filter bank.
Some Aspects on Filter Design for Target Tracking
Bertil Ekstrand
2012-01-01
Tracking filter design is discussed. It is argued that the basis of the present stochastic paradigm is questionable. White process noise is not adequate as a model for target manoeuvring, stochastic least-square optimality is not relevant or required in practice, the fact that requirements are necessary for design is ignored, and root mean square (RMS) errors are insufficient as performance measure. It is argued that there is no process noise and that the covariance of the assumed process noi...
Design Optimization of Diesel Particulate Filter Using CFD
Mr. Y. Rajasekhar Reddy; Mr. K. Srinivasa Chalapathi
2015-01-01
The diesel particulate filter (DPF) is a device designed to remove diesel particulate matter or soot from the exhaust gas of a diesel engine. A series of tests have been performed on a downscaled DPF prototype. This prototype had high filtration efficiency. Then the next step is to study the soot and ash handling capacity of DPF system and perform tests on a full-scale prototype. In order to move forward to the next step the functionality of the filter should be investigated. More...
Analysis and Design of Offset QPSK Using Redundant Filter Banks
This paper considers the analysis and design of OQPSK digital modulation. We first establish the discrete time formulation, which allows us to find the equivalent redundant filter banks. It is well known that redundant filter banks are related with redundant transformation of the Frame theory. According to the Frame theory, the redundant transformations and corresponding representations are not unique. In this way, we show that the solution to the pulse shaping problem is not unique. Then we use this property to minimize the effect of the channel noise in the reconstructed symbol stream. We evaluate the performance of the digital communication using numerical examples.
Providing Eligibility Criteria On Turbocharger Filter Silencer Design Processes
Adem GÜLERYÜZ
2013-06-01
Full Text Available Supply of ventilation air to either the engine room or diesel engine directly affects engine performances. Main criteria is supply of air volume and pressure into the cylinder. When Air starts to come until the cylinders, there many points which behave as restrictions. These are ventilation grills. ventilation fans, ventilation casings, misteliminators, manual or pneumatically adjusted fan dampers, number of bending of ventilation casing, cleanness of casings, air flow speed, air filters, turbocharger filter and silencers, engine’s scavenge air cooler restrictions. Here, we focused on optimum required air need through turbocharger for local diesel engine. While researching actual need, new turbocharger filter were designed and manufactured for engine manufacturer.
Ken Smigielski
2009-04-01
Full Text Available An air filter is a significant element of any mechanical ventilation system. However, the importance and performance evaluation of air filters have not been well publicized and related scientific reports are scarce. In this study, a transportable, off-line, air filter-testing unit (the Unit was designed and utilized to simulate the filter housing of a mechanical ventilation system. The Unit was designed, assembled, and operated in a laboratory. To demonstrate the applications of the Unit, a series of air filter handling and installation scenarios was performed to determine the characteristic curve and capture efficiencies of a selected set of HEPA filters. The research project produced a transportable, closed system air filter testing unit. The Unit incorporated a fan, a damper to adjust air flowrate, a filter-housing (consisting of a mixing chamber, a filter-frame, and a pressure-gauge, and ducting with ports to introduce challenge particles and monitor them after filtration. By using the Unit, the detrimental effects of damaged filter-media, damaged filter-gasket, and improper installation of air filters on their capture efficiencies were clearly demonstrated. An air filter testing unit, similar to the Unit presented here, can readily be designed, fabricated, and assembled to simulate the filter-housing of mechanical ventilation systems. The assembled unit can be used (1 to determine capture efficiency of air filters and their characteristic curve, (2 to demonstrate the negative effects of improper handling and installation of air filters, and (3 as an effective investigative and educational tool.
Choi, Hee Dong; Kim, Chang Shuk; Byun, Soo Hyun; Lee, Jae Yun; Sun, Gwang Min; Kim, Suk Kwon [Seoul National University, (Korea)
2000-04-01
I. Objectives and Necessity of the Project. Development of a boron concentration analysis system used for BNCT. Development of test techniques for BNCT facility. II. Contents and Scopes of the Project. (1) Design of a boron concentration analysis system at HANARO. (2) Component machining and instruments purchase, performance test. (3) Calculation and measurement of diffracted polychromatic beam quality. (4) Test procedures for boron concentration analysis system and BNCT facility. III. Result of the Project (1) Diffracted neutron beam quality for boron concentration analysis. (neutron flux: 1.2 * 10{sup 8} n/cm{sup 2}s, Cd-ratio : 1,600) (2) Components and instruments of the boron concentration analysis system. (3) Diffracted neutron spectrum and flux. (4) Test procedures for boron concentration analysis system and BNCT facility. 69 refs., 44 figs., 14 tabs. (Author)
Ridge filter design for a particle therapy line
Kim, Chang Hyeuk; Han, Garam; Lee, Hwa-Ryun; Kim, Hyunyong; Jang, Hong Suk; Kim, Jeong Hwan; Park, Dong Wook; Jang, Sea Duk; Hwang, Won Taek; Kim, Geun-Beom; Yang, Tae-Keun
2014-05-01
The beam irradiation system for particle therapy can use a passive or an active beam irradiation method. In the case of an active beam irradiation, using a ridge filter would be appropriate to generate a spread-out Bragg peak (SOBP) through a large scanning area. For this study, a ridge filter was designed as an energy modulation device for a prototype active scanning system at MC-50 in Korea Institute of Radiological And Medical Science (KIRAMS). The ridge filter was designed to create a 10 mm of SOBP for a 45-MeV proton beam. To reduce the distal penumbra and the initial dose, [DM] determined the weighting factor for Bragg Peak by applying an in-house iteration code and the Minuit Fit package of Root. A single ridge bar shape and its corresponding thickness were obtained through 21 weighting factors. Also, a ridge filter was fabricated to cover a large scanning area (300 × 300 mm2) by Polymethyl Methacrylate (PMMA). The fabricated ridge filter was tested at the prototype active beamline of MC-50. The SOBP and the incident beam distribution were obtained by using HD-810 GaF chromatic film placed at a right triangle to the PMMA block. The depth dose profile for the SOBP can be obtained precisely by using the flat field correction and measuring the 2-dimensional distribution of the incoming beam. After the flat field correction is used, the experimental results show that the SOBP region matches with design requirement well, with 0.62% uniformity.
On the 252Cf primary and secondary gamma rays and epithermal neutron flux for BNCT
Ghassoun, J.; Merzouki, A.; El Morabiti, A.; Jehouani, A.
2007-10-01
Monte Carlo simulation has been used to calculate the different components of neutrons and secondary gamma rays originated by 252Cf fission and also the primary gamma rays emitted directly by the 252Cf source at the exit face of a compact system designed for the BNCT. The system consists of a 252Cf source and a moderator/reflector/filter assembly. To study the material properties and configuration possibilities, the MCNP code has been used. The moderator/reflector/filter arrangement is optimised to moderate neutrons to epithermal energy and, as far as possible, to get rid of fast and thermal neutrons and photons from the therapeutic beam. To reduce the total gamma contamination and to have a sufficiently high epithermal neutron flux we have used different photon filters of different thickness. Our analysis showed that the use of an appropriate filter leads to a gamma ray flux reduction without affecting the epithermal neutron beam quality at the exit face of the system.
On the {sup 252}Cf primary and secondary gamma rays and epithermal neutron flux for BNCT
Ghassoun, J. [LPTN, Departement de Physique, Faculte des Sciences Semlalia, BP 2390, 40000 Marrakech (Morocco)], E-mail: ghassoun@ucam.ac.ma; Merzouki, A. [LPTN, Departement de Physique, Faculte des Sciences Semlalia, BP 2390, 40000 Marrakech (Morocco); Remote Sensing and Geomatics of the Environnement Laboratory, Ottawa-Carleton Geoscience Centre, Marion Hall-140Louis Pasteur Ottawa, ON, KIN 6N5 (Canada); El Morabiti, A.; Jehouani, A. [LPTN, Departement de Physique, Faculte des Sciences Semlalia, BP 2390, 40000 Marrakech (Morocco)
2007-10-15
Monte Carlo simulation has been used to calculate the different components of neutrons and secondary gamma rays originated by {sup 252}Cf fission and also the primary gamma rays emitted directly by the {sup 252}Cf source at the exit face of a compact system designed for the BNCT. The system consists of a {sup 252}Cf source and a moderator/reflector/filter assembly. To study the material properties and configuration possibilities, the MCNP code has been used. The moderator/reflector/filter arrangement is optimised to moderate neutrons to epithermal energy and, as far as possible, to get rid of fast and thermal neutrons and photons from the therapeutic beam. To reduce the total gamma contamination and to have a sufficiently high epithermal neutron flux we have used different photon filters of different thickness. Our analysis showed that the use of an appropriate filter leads to a gamma ray flux reduction without affecting the epithermal neutron beam quality at the exit face of the system.
On the 252Cf primary and secondary gamma rays and epithermal neutron flux for BNCT
Monte Carlo simulation has been used to calculate the different components of neutrons and secondary gamma rays originated by 252Cf fission and also the primary gamma rays emitted directly by the 252Cf source at the exit face of a compact system designed for the BNCT. The system consists of a 252Cf source and a moderator/reflector/filter assembly. To study the material properties and configuration possibilities, the MCNP code has been used. The moderator/reflector/filter arrangement is optimised to moderate neutrons to epithermal energy and, as far as possible, to get rid of fast and thermal neutrons and photons from the therapeutic beam. To reduce the total gamma contamination and to have a sufficiently high epithermal neutron flux we have used different photon filters of different thickness. Our analysis showed that the use of an appropriate filter leads to a gamma ray flux reduction without affecting the epithermal neutron beam quality at the exit face of the system
Design of switched-capacitor filter circuits using low gain amplifiers
Serra, Hugo Alexandre de Andrade
2015-01-01
This book describes the design of switched-capacitor filter circuits using low gain amplifiers and demonstrates some techniques that can minimize the effects of parasitic capacitances during the design phase. Focus is given in the design of low-pass and band-pass SC filters, and how higher order filters can be achieved using cascaded biquadratic filter sections. The authors also describe a low voltage implementation of a low-pass SC filter.
INEL BNCT research program: Annual report, 1995
Venhuizen, J.R. [ed.
1996-04-01
This report is a summary of the progress and research produced for the Idaho National Engineering Laboratory (INEL) Boron Neutron Capture Therapy (BNCT) Research Program for calendar year 1995. Contributions from the principal investigators about their individual projects are included, specifically, physics (treatment planning software, real-time neutron beam measurement dosimetry), and radiation biology (large animal models efficacy studies). Design of a reactor based epithermal neutron extraction facility is discussed in detail. Final results of boron magnetic resonance imagining is included for both borocaptate sodium (BSH) and boronophenylalanine (BPA) in rats, and BSH in humans. Design of an epithermal neutron facility using electron linear accelerators is presented, including a treatise on energy removal from the beam target. Information on the multiple fraction injection of BSH in rats is presented.
INEL BNCT research program: Annual report, 1995
This report is a summary of the progress and research produced for the Idaho National Engineering Laboratory (INEL) Boron Neutron Capture Therapy (BNCT) Research Program for calendar year 1995. Contributions from the principal investigators about their individual projects are included, specifically, physics (treatment planning software, real-time neutron beam measurement dosimetry), and radiation biology (large animal models efficacy studies). Design of a reactor based epithermal neutron extraction facility is discussed in detail. Final results of boron magnetic resonance imagining is included for both borocaptate sodium (BSH) and boronophenylalanine (BPA) in rats, and BSH in humans. Design of an epithermal neutron facility using electron linear accelerators is presented, including a treatise on energy removal from the beam target. Information on the multiple fraction injection of BSH in rats is presented
Dynamical decoupling sequence construction as a filter-design problem
Biercuk, M J
2010-01-01
Over the past decade we have seen an explosion of demonstrations of quantum coherence in atomic, optical, and condensed matter systems. These developments have placed a new emphasis on the production of robust and optimal quantum control techniques in the presence of environmental noise. We discuss the use of dynamical decoupling as a form of open-loop quantum control capable of suppressing the effects of decoherence in quantum coherent systems. We introduce the concept of dynamical decoupling pulse-sequence construction as a filter-design problem, making connections with radiofrequency filter design from electrical engineering in the analysis of pulse-sequence performance. Our work takes this perspective in addressing both "standard" sequences derived from nuclear magnetic resonance and novel optimized sequences developed in the context of quantum information. We describe the physics underlying the functionality of various sequences, and compare their relative capabilities. Additionally, we review new techni...
Lee, Woong-Bi; Kim, Cheolsun; Ju, Gun Wu; Lee, Yong Tak; Lee, Heung-No
2016-05-01
Miniature spectrometers have been widely developed in various academic and industrial applications such as bio-medical, chemical and environmental engineering. As a family of spectrometers, optical filter-array based spectrometers fabricated using CMOS or Nano technology provide miniaturization, superior portability and cost effectiveness. In filterarray based spectrometers, the resolution which represents the ability how closely resolve two neighboring spectra, depends on the number of filters and the characteristics of the transmission functions (TFs) of the filters. In practice, due to the small-size and low-cost fabrication, the number of filters is limited and the shape of the TF of each filter is nonideal. As a development of modern digital signal processing (DSP), the spectrometers are equipped with DSP algorithms not only to alleviate distortions due to unexpected noise or interferences among filters but also reconstruct the original signal spectrum. For a high-resolution spectrum reconstruction by the DSP, the TFs of the filters need to be sufficiently uncorrelated with each other. In this paper, we present a design of optical thin-film filters which have the uncorrelated TFs. Each filter consists of multiple layers of high- and low-refractive index materials deposited on a substrate. The proposed design helps the DSP algorithm to improve resolution with a small number of filters. We demonstrate that a resolution of 5 nm within a range from 500 nm to 1100 nm can be achieved with only 64 filters.
XIE Xuemei
2007-01-01
In this paper, a method is proposed to construct recombination nonuniform cosine-modulated filter banks (CMFBs)with a perfect-reconstruction property and with arbitrary filter lengths. In this filter bank (FB) structure, certain channels of an original M-channel uniform FB are merged by a set of transmultiplexers (TMUXs), yielding nonuniform outputs, and the length restrictions on the original CMFB and the recombination TMUXs are avoided, allowing them to have arbitrary filter lengths. By imposing certain improved matching conditions on the prototype filters, nonuniform FBs with arbitrary filter lengths and with good properties can be obtained.As a result, the flexibility of selecting modulation types and filter lengths is greatly increased in the design of recombination nonuniform CMFBs. Another benefit due to the flexibility is that the system delay can be reduced.
A feasibility study of the Tehran research reactor as a neutron source for BNCT
Investigation on the use of the Tehran Research Reactor (TRR) as a neutron source for Boron Neutron Capture Therapy (BNCT) has been performed by calculating and measuring energy spectrum and the spatial distribution of neutrons in all external irradiation facilities, including six beam tubes, thermal column, and the medical room. Activation methods with multiple foils and a copper wire have been used for the mentioned measurements. The results show that (1) the small diameter and long length beam tubes cannot provide sufficient neutron flux for BNCT; (2) in order to use the medical room, the TRR core should be placed in the open pool position, in this situation the distance between the core and patient position is about 400 cm, so neutron flux cannot be sufficient for BNCT; and (3) the best facility which can be adapted for BNCT application is the thermal column, if all graphite blocks can be removed. The epithermal and fast neutron flux at the beginning of this empty column are 4.12×109 and 1.21×109 n/cm2/s, respectively, which can provide an appropriate neutron beam for BNCT by designing and constructing a proper Beam Shaping Assembly (BSA) structure. - Highlights: • The feasibility of using of TRR for BNCT has been investigated. • Neutron energy spectrum at all external irradiation facilities of TRR have been measured and calculated. • Spatial distribution of neutrons have been measured using copper wire activation method
Sagar R. Patil
2015-11-01
Full Text Available In automobile vehicles mostly plastic molded panel filters used for the purpose of engine air filtration. Fibrous structured cellulose media were being used with different permeability’s according to requirement of rated air flow rate required for the engine. To optimize the filter pleat design of automotive panel air filter, it is important to study correlation of pressure drop, dust holding capacity & efficiency. The main role of a filter is to provide least pressure drop with high dust holding and efficiency. A channel made for the testing of different pleat designs. This research comprises of experimental design & evaluation of filter element with variable pleat depth and pleat density. This assessment offers the selection of pleat design according to the performance requirements.
Design and optimization of multipole lens and Wien filter systems
The differential algebra (DA) method has been employed to compute the optical properties and aberrations up to the fifth order of multipole systems containing electrostatic and magnetic round, quadrupole, hexapole and octopole lenses, and Wien filters. A new software package has been developed, which computes the geometrical and chromatic aberrations up to the fifth order by using a single DA ray trace. It also has an optimization module where a weighted set of aberrations can be minimized by the automatic adjustment of a set of user-defined system variables. In this paper, we present our new method for designing and optimizing multipole systems including Wien filters, and illustrate its application with three relevant examples.
Combination of fractionated photon radiation and BNCT
Because of the relatively low normal brain dose, BNCT allows additional photon radiation sufficient to maintain a total normal brain dose below the tolerance limit. We started a new protocol with a combination of fractionated, extended local photon radiation, and BPA- and BSH-mediated BNCT. In this protocol, newly diagnosed glioblastoma were treated with BPA (250 mg/kg) - and BSH (100 mg/kg) - mediated BNCT followed by fractionated photon radiation. The BNCT dose for the normal brain was restricted to less than 13 GyEq. The fractionated photon radiation at a dose of 30/15 fr or 30.6 Gy/17 fr was planned to irradiate a T2 high-intensity area of post-BNCT MRI. So far, 6 patients have been treated by this protocol. The clinical course, dose distribution, tumor response, and adverse events will be discussed herein. (author)
Fixed-Point Design of Generalized Comb Filters: A Statistical Approach
Laddomada, Massimiliano
2008-01-01
This paper is concerned with the problem of designing computationally efficient Generalized Comb Filters (GCF). Basically, GCF filters are anti-aliasing filters that guarantee superior performance in terms of selectivity and quantization noise rejection compared to classical comb filters, when used as decimation filters in multistage architectures. Upon employing a partial polyphase (PP) architecture proposed in a companion paper, we develop a sensitivity analysis in order to investigate the effects of the coefficients' quantization on the frequency response of the designed filters. We show that the sensitivity of the filter response to errors in the coefficients is dependent on the particular split of the decimation factor between the two sub-filters constituting the PP architecture. The sensitivity analysis is then used for developing a fixed-point implementation of a sample filter from the class of GCF filters, used as reference filter throughout the paper. Finally, we present computer simulations in order...
SkyMapper Filter Set: Design and Fabrication of Large Scale Optical Filters
Bessell, Michael; Schmidt, Brian; Keller, Stefan; Tisserand, Patrick; Francis, Paul
2011-01-01
The SkyMapper Southern Sky Survey will be conducted from Siding Spring Observatory with u, v, g, r, i and z filters that comprise glued glass combination filters of dimension 309x309x15 mm. In this paper we discuss the rationale for our bandpasses and physical characteristics of the filter set. The u, v, g and z filters are entirely glass filters which provide highly uniform band passes across the complete filter aperture. The i filter uses glass with a short-wave pass coating, and the r filter is a complete dielectric filter. We describe the process by which the filters were constructed, including the processes used to obtain uniform dielectric coatings and optimized narrow band anti-reflection coatings, as well as the technique of gluing the large glass pieces together after coating using UV transparent epoxy cement. The measured passbands including extinction and CCD QE are presented.
A geometric method for optimal design of color filter arrays.
Hao, Pengwei; Li, Yan; Lin, Zhouchen; Dubois, Eric
2011-03-01
A color filter array (CFA) used in a digital camera is a mosaic of spectrally selective filters, which allows only one color component to be sensed at each pixel. The missing two components of each pixel have to be estimated by methods known as demosaicking. The demosaicking algorithm and the CFA design are crucial for the quality of the output images. In this paper, we present a CFA design methodology in the frequency domain. The frequency structure, which is shown to be just the symbolic DFT of the CFA pattern (one period of the CFA), is introduced to represent images sampled with any rectangular CFAs in the frequency domain. Based on the frequency structure, the CFA design involves the solution of a constrained optimization problem that aims at minimizing the demosaicking error. To decrease the number of parameters and speed up the parameter searching, the optimization problem is reformulated as the selection of geometric points on the boundary of a convex polygon or the surface of a convex polyhedron. Using our methodology, several new CFA patterns are found, which outperform the currently commercialized and published ones. Experiments demonstrate the effectiveness of our CFA design methodology and the superiority of our new CFA patterns. PMID:20858581
Design Of EMI Filter For Flash Lamp Power Supply
Amrita Bhatt
2015-08-01
Full Text Available Abstract Conducted and radiated electromagnetic interference in embedded and VLSI systems have become important in recent years with increase in clock frequency and reduction in physical dimensions of interconnects. It is important to understand the noise components in terms of current paths and the mitigation techniques. Although the common mode and differential mode components of conducted noise are analyzed in the context of a power electronics system the analytical and theoretical techniques hold good for other domains as well such as embedded systems and VLSI. This paper deals with modelling design and development of an EMI filter for conducted mode noise in flash lamp power supply. Also a design procedure of EMI filters sustaining to the military standard 461E is presented and it is based on practical measurement of conducted emissions. Design procedure in this paper considers common mode and differential mode separately. The paper also consists of considerations for magnetic core material integrated common mode CM common mode choke size optimization and differential mode DM choke etc. Design examples are given and are experimentally verified.
AESOP- INTERACTIVE DESIGN OF LINEAR QUADRATIC REGULATORS AND KALMAN FILTERS
Lehtinen, B.
1994-01-01
AESOP was developed to solve a number of problems associated with the design of controls and state estimators for linear time-invariant systems. The systems considered are modeled in state-variable form by a set of linear differential and algebraic equations with constant coefficients. Two key problems solved by AESOP are the linear quadratic regulator (LQR) design problem and the steady-state Kalman filter design problem. AESOP is designed to be used in an interactive manner. The user can solve design problems and analyze the solutions in a single interactive session. Both numerical and graphical information are available to the user during the session. The AESOP program is structured around a list of predefined functions. Each function performs a single computation associated with control, estimation, or system response determination. AESOP contains over sixty functions and permits the easy inclusion of user defined functions. The user accesses these functions either by inputting a list of desired functions in the order they are to be performed, or by specifying a single function to be performed. The latter case is used when the choice of function and function order depends on the results of previous functions. The available AESOP functions are divided into several general areas including: 1) program control, 2) matrix input and revision, 3) matrix formation, 4) open-loop system analysis, 5) frequency response, 6) transient response, 7) transient function zeros, 8) LQR and Kalman filter design, 9) eigenvalues and eigenvectors, 10) covariances, and 11) user-defined functions. The most important functions are those that design linear quadratic regulators and Kalman filters. The user interacts with AESOP when using these functions by inputting design weighting parameters and by viewing displays of designed system response. Support functions obtain system transient and frequency responses, transfer functions, and covariance matrices. AESOP can also provide the user
Design of a Symmetrical Microstrip Bandpass Filter for S-Band Frequency Range
Mohd F. Ain; Mandeep S.J. Singh; Prabhu; Syed I. S. Hassan
2007-01-01
A new type of microstrip bandpass filter is presented with a center frequency operation at 2.5GHz which lies in the S-band frequency range. The filter is designed to be much smaller compared to the same type of parallel-coupled bandpass filter. The simulation results are excellent and the filter is suitable for integration within various microwave subsystems.
Dynamical decoupling sequence construction as a filter-design problem
Biercuk, M J; Doherty, A C [Centre for Engineered Quantum Systems, School of Physics, University of Sydney, NSW 2006 (Australia); Uys, H, E-mail: michael.biercuk@sydney.edu.au, E-mail: andrew.doherty@sydney.edu.au, E-mail: huys@csir.co.za [National Laser Centre, Council for Scientific and Industrial Research, Pretoria (South Africa)
2011-08-14
Over the past decade we have seen an explosion of demonstrations of quantum coherence in atomic, optical and condensed matter systems. These developments have placed a new emphasis on the production of robust and optimal quantum control techniques in the presence of environmental noise. We discuss the use of dynamical decoupling as a form of open-loop quantum control capable of suppressing the effects of dephasing in quantum coherent systems. We introduce the concept of dynamical decoupling pulse-sequence construction as a filter-design problem, making connections with filter design from control theory and electrical engineering in the analysis of pulse-sequence performance for the preservation of the phase degree of freedom in a quantum superposition. A detailed mathematical description of how dephasing and its suppression can be reduced to a linear control problem is provided, and used as motivation and context for studies of the filtration properties of various dynamical decoupling sequences. Our work then takes this practical perspective in addressing both 'standard' sequences derived from nuclear magnetic resonance and novel optimized sequences developed in the context of quantum information. Additionally, we review new techniques for the numerical construction of optimized pulse sequences in this light. We show how the filter-design perspective permits concise comparisons of the relative capabilities of these sequences and reveals the physics underlying their functionality. The use of this new analytical framework allows us to derive new insights into the performance of these sequences and reveals important limiting issues, such as the effect of digital clocking on optimized sequence performance.
Dynamical decoupling sequence construction as a filter-design problem
Over the past decade we have seen an explosion of demonstrations of quantum coherence in atomic, optical and condensed matter systems. These developments have placed a new emphasis on the production of robust and optimal quantum control techniques in the presence of environmental noise. We discuss the use of dynamical decoupling as a form of open-loop quantum control capable of suppressing the effects of dephasing in quantum coherent systems. We introduce the concept of dynamical decoupling pulse-sequence construction as a filter-design problem, making connections with filter design from control theory and electrical engineering in the analysis of pulse-sequence performance for the preservation of the phase degree of freedom in a quantum superposition. A detailed mathematical description of how dephasing and its suppression can be reduced to a linear control problem is provided, and used as motivation and context for studies of the filtration properties of various dynamical decoupling sequences. Our work then takes this practical perspective in addressing both 'standard' sequences derived from nuclear magnetic resonance and novel optimized sequences developed in the context of quantum information. Additionally, we review new techniques for the numerical construction of optimized pulse sequences in this light. We show how the filter-design perspective permits concise comparisons of the relative capabilities of these sequences and reveals the physics underlying their functionality. The use of this new analytical framework allows us to derive new insights into the performance of these sequences and reveals important limiting issues, such as the effect of digital clocking on optimized sequence performance.
Dynamical decoupling sequence construction as a filter-design problem
Biercuk, M. J.; Doherty, A. C.; Uys, H.
2011-08-01
Over the past decade we have seen an explosion of demonstrations of quantum coherence in atomic, optical and condensed matter systems. These developments have placed a new emphasis on the production of robust and optimal quantum control techniques in the presence of environmental noise. We discuss the use of dynamical decoupling as a form of open-loop quantum control capable of suppressing the effects of dephasing in quantum coherent systems. We introduce the concept of dynamical decoupling pulse-sequence construction as a filter-design problem, making connections with filter design from control theory and electrical engineering in the analysis of pulse-sequence performance for the preservation of the phase degree of freedom in a quantum superposition. A detailed mathematical description of how dephasing and its suppression can be reduced to a linear control problem is provided, and used as motivation and context for studies of the filtration properties of various dynamical decoupling sequences. Our work then takes this practical perspective in addressing both 'standard' sequences derived from nuclear magnetic resonance and novel optimized sequences developed in the context of quantum information. Additionally, we review new techniques for the numerical construction of optimized pulse sequences in this light. We show how the filter-design perspective permits concise comparisons of the relative capabilities of these sequences and reveals the physics underlying their functionality. The use of this new analytical framework allows us to derive new insights into the performance of these sequences and reveals important limiting issues, such as the effect of digital clocking on optimized sequence performance.
TL detectors in BNCT dosimetry
The main detectors for characterising and controlling of BNCT beams are activation foils and paired ionisation chambers. Thermoluminescent (TL) dosimeters are also of interest because of their following advantages: i) small physical size, ii) no need for high voltage or cables, i.e. stand alone character, and iii) suitability for large scale measurements; with TL dosimeters it is possible to measure depth dose curves and profiles at the same time, with one irradiation. Also, TL dosimeters may be possible detectors for in vivo use. At the Finnish BNCT facility, a TL detector MTS-Ns of TLD Niewiadomski and Co. (Krakow, Poland) with an ultrathin active LiF:Mg,Ti layer for small self-shielding of thermal neutrons was selected for use as a neutron sensitive dosimeter. A TL detector MCP-7s (7LiF:Mg,Cu,P) of the same manufacturer was used for gamma detection because of its high sensitivity to gamma radiation compared to that to high LET radiation. The gamma dose and neutron fluence distributions have been measured in PMMA, water and brain substitute liquid phantoms at the BNCT beam. Gamma dose and neutron fluence profiles measured with TL detectors correlate with those calculated using DORT (Two Dimensional Discrete Ordinates Transport Code) and measured with ionisation chambers. NITS-Ns TL detectors were found to measure accurately (8%, 1 S.D.) the relative neutron fluence, and therefore to be a useful addition to the activation foils in BNCT neutron dosimetry. Due to the high uncertainty of the thermal neutron sensitivity of the MCP-7s TL detectors, the absorbed gamma doses can be measured with MCP-7s detectors within 20% in the mixed neutron-gamma field of BNCT. The treatments of glioma patients at the Finnish BNCT facility will start in the spring 1999. The doses to the target volume and sensitive organs, i.e. brain, will be calculated individually in the dose planning. Since it is also necessary to monitor the absorbed doses to the head and to the body, in vivo
An accelerator-based BNCT (Boron Neutron Capture Therapy) facility is being constructed at the Ibaraki Neutron Medical Research Center. It consists of a proton linac (8 MeV energy and 10 mA average current), a beryllium target, and a moderator system to provide an epi-thermal neutron flux for patient treatment. The technology choices for this present system were driven by the need to site the facility in a hospital and where low residual activity is essential. The maximum neutron energy produced from an 8 MeV-proton is 6 MeV, which is below the threshold energy of the main nuclear reactions which produce radioactive products. The down side of this technology choice is that it produces a high density heat load on the target so that cooling and hydrogen blistering amelioration prevent sever challenges requiring successful R and D progress. The latest design of the target and moderator system shows that a flux of 2.5x109 epi-thermal neutrons/cm2/sec can be obtained. This is two times higher than the flux from the existing nuclear reactor based BNCT facility at JAEA (JRR-4). (author)
A Practical Design of Lumped, Semi-lumped & Microwave Cavity Filters
Natarajan, Dhanasekharan
2013-01-01
This book presents the application of microwave literature for designing lumped/semi-lumped filters and combline/iris-coupled microwave cavity filters. It provides the physical understanding of the terms and characteristics of radio frequency (RF) filters. The book complements engineering text books on RF components and provides support for the project assignments of students. In addition to the functional design of RF filters, the integrated design approach for produceability and reliability is explained.
Design of Low Pass Digital FIR Filter Using Cuckoo Search Algorithm
Taranjit Singh
2014-08-01
Full Text Available This paper presents a novel approach of designing linear phase FIR low pass filter using cuckoo Search Algorithm (CSA. FIR filter design is a multi-modal optimization problem. The conventional optimization techniques are not efficient for digital filter design. An iterative method is introduced to find the best solution of FIR filter design problem.Flat passband and high stopband attenuation are the major characteristics required in FIR filter design. To achieve these characteristics, a Cuckoo Search algorithm (CSA is proposed in this paper. CSA have been used here for the design of linear phase finite impulse response (FIR filters. Results are presented in this paper that seems to be promising tool for FIR filter design
Implementation of BNCT treatment planning procedures
Estimation of radiation doses delivered during boron neutron capture therapy (BNCT) requires combining data on spatial distribution of both the thermal neutron fluence and the 10B concentration, as well as the relative biological effectiveness of various radiation dose components in the tumor and normal tissues. Using the treatment planning system created at Idaho National Engineering and Environmental Laboratory and the procedures we had developed for clinical trials, we were able to optimize the treatment position, safely deliver the prescribed BNCT doses, and carry out retrospective analyses and reviews. In this paper we describe the BNCT treatment planning process and its implementation in the ongoing dose escalation trials at Brookhaven National Laboratory. (author)
Stella, S.; Bazani, A.; Ballarini, F.; Bortolussi, S.; Protti, N.; Altieri, S. [Department of Nuclear and Theoretical Physics, University of Pavia (Italy); Istituto Nazionale di Fisica Nucleare (INFN), Section of Pavia (Italy); Bruschi, P. [Department of Nuclear and Theoretical Physics, University of Pavia (Italy)
2011-07-01
In preclinical and clinical Boron Neutron Capture Therapy studies the knowledge of the amount of {sup 10}B in blood and tissues is very important. The boron concentration measurements method used in Pavia (Italy) is based on the charged particles spectrometry of thin tissue cuts irradiated in the Thermal Column of the TRIGA reactor of the University. In order to perform measurements in biological liquids such as blood and urine, or in other tissue that cannot be cut in slices, a Prompt Gamma Neutron Activation Analysis (PGNAA) facility is being designed, which measures {sup 10}B concentration detecting the prompt gamma from boron nuclear capture reaction. At the TRIGA reactor in Pavia, there are four horizontal channels, potentially available for PGNAA. The choice of the suitable channel, and the design of its configuration, were achieved using the Monte Carlo neutron transport code MCNP4c2. To perform the simulations, an input code already validated, describing the reactor structure and the neutron source, was used. The calculations were implemented applying non-analog techniques for the neutron transport, that are necessary to obtain a sufficient statistic in every positions along the channel and especially at its end. The selection of the channel for PGNAA installation was carried out by comparing the simulated fluxes obtained in the different channels at the present configuration. The channel shielded by the core reflector was chosen, because the graphite lowers the fast component of the neutrons, with no need to insert additional material in the facility. The thermal flux at its end is 1.7 x 10{sup 8} n/cm{sup 2} s with thermal-to-total neutron flux ratio around 0.8. Subsequently a bismuth block for gamma radiation shielding and blocks of single crystal sapphire as filter for fast neutron component were inserted in the channel. Other components of the facility that are under study are a collimator and the beam catcher. (author)
Modernization of sump filters design on ROVNO NPP
Taking into account the major importance to solve sump plugging in case of primary break, modernization of sump filters design on ROVNO NPP has been engaged. This action has been realized using a > approach, which had been proposed by the Commission of the European Community (CEC) in 1998, with the purpose of effectiveness increase of activities under realization of TACIS program projects. This paper gives a short summary of the different actions performed by the Technical Support Organization (IRSN, France), the State Scientific and Technical Center for Nuclear and Radiation Safety (SSTC NRS, Ukraine), the State Nuclear Regulatory Committee of Ukraine (SNRCU), the ROVNO NPP, assisted by EDF and the designer (FORTUM and FRAMATOME). (authors)
Gabor Filter Optimization Design for Iris Texture Analysis
Tao Xu; Xing Ming; Xiaoguang Yang
2004-01-01
This paper deals with an optimization design method for the Gabor filters based on the analysis of an iris texture model. By means of analyzing the properties of an iris texture image, the energy distribution regularity of the iris texture image measured by the average power spectrum density is exploited, and the theoretical ranges of the efficient valued frequency and orientation parameters can also be deduced. The analysis shows that the energy distribution of the iris texture is generally centralized around lower frequencies in the spatial frequency domain. Accordingly, an iterative algorithm is designed to optimize the Gabor parameter field. The experimental results indicate the validity of the theory and efficiency of the algorithm.
Design of the LC+trap filter for a current source rectifier
Min, Huang; Wang, Xiongfei; Loh, Poh Chiang; Blaabjerg, Frede
2015-01-01
capacitor voltage and the line current THD for space vector modulation. The resonance of the input filter can be excited by the Pulse Width Modulation (PWM) and a simple passive damping can damp the resonances. The analysis and design of the input filter have been verified by simulations in MATLAB/Simulink.......This paper investigates an LC + trap filter for current source converters to improve the switching harmonic attenuation. The resonant frequency characteristics of the filter of current source rectifier are analyzed. A filter design procedure is proposed based on the input power factor, filter...
Measurement and simulation of the TRR BNCT beam parameters
Bavarnegin, Elham; Sadremomtaz, Alireza; Khalafi, Hossein; Kasesaz, Yaser; Golshanian, Mohadeseh; Ghods, Hossein; Ezzati, Arsalan; Keyvani, Mehdi; Haddadi, Mohammad
2016-09-01
Recently, the configuration of the Tehran Research Reactor (TRR) thermal column has been modified and a proper thermal neutron beam for preclinical Boron Neutron Capture Therapy (BNCT) has been obtained. In this study, simulations and experimental measurements have been carried out to identify the BNCT beam parameters including the beam uniformity, the distribution of the thermal neutron dose, boron dose, gamma dose in a phantom and also the Therapeutic Gain (TG). To do this, the entire TRR structure including the reactor core, pool, the thermal column and beam tubes have been modeled using MCNPX Monte Carlo code. To measure in-phantom dose distribution a special head phantom has been constructed and foil activation techniques and TLD700 dosimeter have been used. The results show that there is enough uniformity in TRR thermal BNCT beam. TG parameter has the maximum value of 5.7 at the depth of 1 cm from the surface of the phantom, confirming that TRR thermal neutron beam has potential for being used in treatment of superficial brain tumors. For the purpose of a clinical trial, more modifications need to be done at the reactor, as, for example design, and construction of a treatment room at the beam exit which is our plan for future. To date, this beam is usable for biological studies and animal trials. There is a relatively good agreement between simulation and measurement especially within a diameter of 10 cm which is the dimension of usual BNCT beam ports. This relatively good agreement enables a more precise prediction of the irradiation conditions needed for future experiments.
DESIGN OF STEPPED IMPEDANCE LOW PASS FILTER AT 2.4GHz
Vishakha Dayal Shrivastava*, Vandana Vikas Thakare
2016-01-01
In this era, life can't be envisioned without wireless communication. The microwave filter is a component which gives frequency selectivity in mobile, radar, satellite communication systems working at microwave frequency. Microwave low pass filter attenuates the unwanted signal above cut off frequency. For stepped impedance filter design high and low impedance lines are used. This paper describes designing of Chebyshev approximated stepped impedance low pass filter at 2.4 GHz with t...
Design and analysis of microstrip photonic band gap filter without etching ground plane
R. N. Baral; P. K. Singhal
2009-01-01
A design of microstrip photonic band gap (PBG) filter is presented in this paper. The band reject filter is compact in structure and provides accurate band gap. The proposed filter has a periodic configuration; the impedance distribution over the length of each period is varied according to a designated sinusoidal function. Both theoretical and experimental results indicate that a bandstop filter with an extremely wide bandwidth can be achieved. Detailed analysis of the frequency response of ...
Criteria for calculating the efficiency of HEPA filters during and after design basis accidents
We have reviewed the literature on the performance of high efficiency particulate air (HEPA) filters under normal and abnormal conditions to establish criteria for calculating the efficiency of HEPA filters in a DOE nonreactor nuclear facility during and after a Design Basis Accident (DBA). The literature review included the performance of new filters and parameters that may cause deterioration in the filter performance such as filter age, radiation, corrosive chemicals, seismic and rough handling, high temperature, moisture, particle clogging, high air flow and pressure pulses. The deterioration of the filter efficiency depends on the exposure parameters; in severe exposure conditions the filter will be structurally damaged and have a residual efficiency of 0%. Despite the many studies on HEPA filter performance under adverse conditions, there are large gaps and limitations in the data that introduce significant error in the estimates of HEPA filter efficiencies under DBA conditions. Because of this limitation, conservative values of filter efficiency were chosen when there was insufficient data
USING GENETIC ALGORITHMS FOR DESIGNING OF FIR DIGITAL FILTERS
Alireza Rezaee
2010-07-01
Full Text Available In this paper, a new technique is presented for the design and optimization of digital FIR filters with coefficients that are presented in canonic signed-digit (CSD format. Since such implementation requires no multipliers, it reduces the hardware cost and lowers the power consumption. The proposed technique considers three goals, the optimum number of coefficients, the optimum wordlength, and the optimum set of coefficients which satisfies the desirable frequency response and ensures the minimum hardware cost by minimizing the number of nonzero digits in CSD representation of the coefficients using Genetic Algorithms (GA. Comparing with equiripple method, the proposed technique results in about 30-40 percent reduction in hardware cost.
Design of Reversible Multipliers for Linear Filtering Applications in DSP
Rakshith Saligram
2013-01-01
Full Text Available Multipliers in DSP computations are crucial. Thus modern DSP systems need to develop low powermultipliers to reduce the power dissipation. One of the efficient ways to reduce power dissipation is by theuse of bypassing technique. If a bit in the multiplier and/or multiplicand is zero the whole array of rowand/or diagonal will be bypassed and hence the name bypass multipliers. This paper presents the columnBypass multiplier and 2-D bypass multiplier using reversible logic; Reversible logic is a more prominenttechnology, having its applications in Low Power CMOS and quantum computations. The switchingactivity of any component in the bypass multiplier depends only on the input bit coefficients. Thesemultipliers find application in linear filtering FFT computational units, particularly during zero paddingwhere there will be umpteen numbers of zeros. A bypass multiplier reduces the number of switchingactivities as well as the power consumption, above which reversible logic design acts to further almostnullify the dissipations
Hydraulic design optimization for hollow fiber filter system
An analytical model has been developed to describe hydraulic characteristics of a hollow fiber membrane filter (HFF) for condensate purification in BWR power plants. Using this model, a module structure was proposed to minimize pressure drop at the beginning of HFF operation. That is, given flow rate of a module, both dimensions of the inner diameter and the length of a single fiber membrane were designed to have optimal values, giving minimum volume for the module. The mechanism of Fe ion crystallization on HFF surface which determines operation life time was clarified and a countermeasure against it was developed. Precoating of amorphous iron crud effectively inhibited crystallization. Taking account of the crystallization, a simulation code was developed to predict pressure drop trend in the course of HFF operation. (author)
Characterisation of an accelerator-based neutron source for BNCT versus beam energy
Agosteo, S; D'Errico, F; Nath, R; Tinti, R
2002-01-01
Neutron capture in sup 1 sup 0 B produces energetic alpha particles that have a high linear energy transfer in tissue. This results in higher cell killing and a higher relative biological effectiveness compared to photons. Using suitably designed boron compounds which preferentially localize in cancerous cells instead of healthy tissues, boron neutron capture therapy (BNCT) has the potential of providing a higher tumor cure rate within minimal toxicity to normal tissues. This clinical approach requires a thermal neutron source, generally a nuclear reactor, with a fluence rate sufficient to deliver tumorcidal doses within a reasonable treatment time (minutes). Thermal neutrons do not penetrate deeply in tissue, therefore BNCT is limited to lesions which are either superficial or otherwise accessible. In this work, we investigate the feasibility of an accelerator-based thermal neutron source for the BNCT of skin melanomas. The source was designed via MCNP Monte Carlo simulations of the thermalization of a fast ...
Clinical results of BNCT for malignant meningiomas
Malignant meningiomas is difficult pathology to be controlled as well as GBM. Since June of 2005, we applied BNCT for 7 cases of malignancy related meningiomas with 13 times neutron irradiation. Five were anaplastic, one was atypical meningiomas and one was sarcoma transformed from meningioma with cervical lymph node metastasis. All cases were introduced after repetitive surgeries and XRT or SRS. Follow-up images were available for 6 cases with observation duration between 2 to 9 months. We applied F-BPA-PET before BNCT in 6 out of 7 cases. One case was received methionine-PET. Five out of 6 cases who received BPA-PET study showed good BPA uptake more than 3 of T/N ratio. One atypical meningiomas cases showed 2.0 of T/N ratio. Original tumor sizes were between 9.2 to 92.7 ml. Two out of 5 anaplastic meningiomas showed CR and all six cases showed radiographic improvements. Clinical symptoms before BNCT such as hemiparesis and facial pain were improved after BNCT, except one case. An huge atypical meningiomas which arisen from tentorium and extended bilateral occipital lobes and brain stem, visual problems were worsened after repetitive BNCT with increase of peritumoral edema. Malignant meningiomas are seemed to be good candidate for BNCT. (author)
Feasibility study of using laser-generated neutron beam for BNCT
The feasibility of using a laser-accelerated proton beam to produce a neutron source, via (p,n) reaction, for Boron Neutron Capture Therapy (BNCT) applications has been studied by MCNPX Monte Carlo code. After optimization of the target material and its thickness, a Beam Shaping Assembly (BSA) has been designed and optimized to provide appropriate neutron beam according to the recommended criteria by International Atomic Energy Agency. It was found that the considered laser-accelerated proton beam can provide epithermal neutron flux of ∼2×106 n/cm2 shot. To achieve an appropriate epithermal neutron flux for BNCT treatment, the laser must operate at repetition rates of 1 kHz, which is rather ambitious at this moment. But it can be used in some BNCT researches field such as biological research. - Highlights: • Feasibility of using laser-accelerated proton beam for BNCT has been investigated. • The considered beam can provide epithermal neutron flux of ~2×106 (n/cm2.shot). • For BNCT treatment, the laser must operate at repetition rates of 1 kHz
Design a Micro-Strip Band Pass Filter for 6 GHz
Ashish Duvey
2012-01-01
Purpose of this paper described about the design of microwave band pass filter by using microstrip layout. A microwave filter is two port network used to control the frequency response. The developments after micro-strip filter are simulated by using IE3D simulator software. Photolithographic process is used for fabrication and after fabrication final testing had done by using the spectrum analyzer.
Design of digital trapezoidal shaping filter based on LabVIEW
It describes the design of a digital trapezoidal shaping filter to nuclear signals based on LabVIEW. A method of optimizing the trapezoidal shaping filter's parameters was presented and tested, and the test results of the effect of shaping filter algorithm were studied. (authors)
Masoudi, S. Farhad, E-mail: masoudi@kntu.ac.ir; Rasouli, Fatemeh S.
2015-08-01
Recent studies in BNCT have focused on investigating appropriate neutron sources as alternatives for nuclear reactors. As the most prominent facilities, the electron linac based photoneutron sources benefit from two consecutive reactions, (e, γ) and (γ, n). The photoneutron sources designed so far are composed of bipartite targets which involve practical problems and are far from the objective of achieving an optimized neutron source. This simulation study deals with designing a compact, optimized, and geometrically simple target for a photoneutron source based on an electron linac. Based on a set of MCNPX simulations, tungsten is found to have the potential of utilizing as both photon converter and photoneutron target. Besides, it is shown that an optimized dimension for such a target slows-down the produced neutrons toward the desired energy range while keeping them economy, which makes achieving the recommended criteria for BNCT of deep-tumors more available. This multi-purpose target does not involve complicated designing, and can be considered as a significant step toward finding application of photoneutron sources for in-hospital treatments. In order to shape the neutron beam emitted from such a target, the beam is planned to pass through an optimized arrangement of materials composed of moderators, filters, reflector, and collimator. By assessment with the recommended in-air parameters, it is shown that the designed beam provides high intensity of desired neutrons, as well as low background contamination. The last section of this study is devoted to investigate the performance of the resultant beam in deep tissue. A typical simulated liver tumor, located within a phantom of human body, was subjected to the irradiation of the designed spectrum. The dosimetric results, including evaluated depth-dose curves and carried out in-phantom parameters show that the proposed configuration establishes acceptable agreement between the appropriate neutron intensity, and
On the Polyphase Decomposition for Design of Generalized Comb Decimation Filters
Laddomada, Massimiliano
2007-01-01
Generalized comb filters (GCFs) are efficient anti-aliasing decimation filters with improved selectivity and quantization noise (QN) rejection performance around the so called folding bands with respect to classical comb filters. In this paper, we address the design of GCF filters by proposing an efficient partial polyphase architecture with the aim to reduce the data rate as much as possible after the Sigma-Delta A/D conversion. We propose a mathematical framework in order to completely char...
Intelligent Optimize Design of LCL Filter for Three-Phase Voltage-Source PWM Rectifier
Sun, Wei; Chen, Zhe; Wu, Xiaojie
2009-01-01
Compared to traditional L filter, a LCL filter is more effective on reducing harmonic distortion at switch frequency. So it is important to choose the LCL filter parameters to achieve good filtering effect. This paper introduces some traditional design methods. Design of a LCL filter by genetic...... algorithm (GA) and particle swam optimization (PSO) are presented in this paper and comparison of the two intelligent optimization. Simulation result and calculate data are provided to prove that intelligent optimization are more effective and simple than traditional methods....
Design of Miniaturized Multiband Filters Using Zero Order Resonators for WLAN Applications
Maryam Shafiee
2015-01-01
Full Text Available The objective of this paper is to design miniaturized narrow- and dual-band filters for WLAN application using zero order resonators by the method of least squares. The miniaturization of the narrow-band filter is up to 70% and that of the dual-band filter is up to 64% compared to the available models in the literature. Two prototype models of the narrow-band and dual-band filters are fabricated and measured, which verify the proposed structure for the filter and its design by the presented method, using an equivalent circuit model.
The experience from the construction of BNCT facility at the LVR-15 reactor
The BNCT project at LVR-15 reactor of NRI for treatment of human brain gliomas is before start of clinical trials. A survey of present conditions is included, the attention is devoted to BNCT facility with epithermal neutron beam first of all. The different materials for filter composition were studied, the calculational methods have been used for the determination of neutron and gamma rays in the reactor geometry. Some configurations were experimentally verified. The effort for improvement of epithermal neutron beam parameters in configuration 1998 was concentrated to block of filters remodelling, improvement of collimator-shutter geometry, the choice of optimal reactor core edge configuration. Awaited results from experiment in June 1999 are described. (author)
The Design of Polymer Planar Optical Triplexer with MMI Filter and Directional Coupler
V. Jerabek
2013-12-01
Full Text Available Optical bidirectional WDM transceiver is a key component of the Passive Optical Network of the Fiber to the Home topology. Essential parts of such transceivers are filters that combine multiplexing and demultiplexing function of optical signal (triplexing filters. In this paper we report about a design of a new planar optical multi-wavelength selective system triplexing filter, which combines a multimode interference filter with directional coupler based on the epoxy polymer SU-8 on Si/SiO2 substrate. The optical triplexing filter was designed using the Beam Propagation Method. The aim of this project was to optimize the triplexing filter optical parameters and to minimize the planar optical wavelength selective system dimensions. The multimode interference filter was used for separation of downstream optical signal in designed optoelectronic integrated WDM transceiver. The directional coupler was used for adding of upstream optical signal.
A Proficient Design of Hybrid Synchronous and Asynchronous Digital FIR Filter using FPGA
B.Paulchamy
2012-07-01
Full Text Available In this paper, a hybrid synchronous and asynchronous digital FIR filter is designed and implemented in FPGA using VHDL. The digital FIR filter of high throughput, low latency operating at above 1.3 GHz was designed. An adaptive high capacity pipelined was introduced in the hybrid synchronous asynchronous design of the filter. The degree of the pipelining is dynamically variable depending upon the input. Concurrent execution of software or program can be achieved in FPGA through parallel processing. The designed digital FIR filter is simulated using ModelSim and implemented using Xilinx. The simulation results are presented for different order such as 3, 6 and 15. The FIR filter designed is synthesized in Xilinx 9.1i and the device utilization report is presented for filter of order 3, 6 and 15.
Interpolation Filter Design for Hearing-Aid Audio Class-D Output Stage Application
Pracný, Peter; Bruun, Erik; Muntal, Pere Llimós
2012-01-01
This paper deals with a design of a digital interpolation filter for a 3rd order multi-bit ΣΔ modulator with over-sampling ratio OSR = 64. The interpolation filter and the ΣΔ modulator are part of the back-end of an audio signal processing system in a hearing-aid application. The aim in this paper...... is to compare this design to designs presented in other state-of-the-art works ranging from hi-fi audio to hearing-aids. By performing comparison, trends and tradeoffs in interpolation filter design are indentified and hearing-aid specifications are derived. The possibilities for hardware reduction...... in the interpolation filter are investigated. Proposed design simplifications presented here result in the least hardware demanding combination of oversampling ratio, number of stages and number of filter taps among a number of filters reported for audio applications....
Construction of a BNCT facility using an 8-MeV high power proton linac in Ibaraki
An accelerator-based BNCT (Boron Neutron Capture Therapy) facility is now under construction and the entire system including the patient treatment system will be installed in the Ibaraki Neutron Advanced Medical Research Center (tentative name). BNCT is expected to give good results for inoperable cancers. In BNCT, pharmaceuticals carry a neutron capture agent containing 10B (Boron 10) selectively into tumor cells. Next thermal or epi-thermal neutrons interact with the 10B and produce α and 7Li-particles. Both of these particles have a very high Linear Energy Transfer (LET) and therefore lose almost all of their energy within a distance comparable to the size of a tumor cell. So far, BNCT has been provided only by nuclear reactors. The promising results shown there by BNCT give the hope that it may become an indispensable treatment modality for many types of cancers. From solely the neutron intensity point of view, nuclear reactors are excellent neutron sources. But as nuclear reactors regularly require long maintenance shut-downs and are subject to strict regulations, hospital operation is completely impractical. Thus we recognize the desirability of an accelerator-based BNCT facility well adapted for use by hospitals. We are aiming at the design and construction of a 'Hospital and Patient friendly' BNCT system. The development of such a BNCT requires multi-disciplinary input and collaboration from a wide spectrum of scientific and technical specialties. To obtain the needed breath and strength, we have organized our team with contributing specialists from diverse institutes and companies. The Ibaraki Medical Center for Advanced Neutron Therapy will be on the IQBRC (Ibaraki Quantum Beam Research Center) campus, which is near the JAEA and KEK Tokai campuses. The building for the BNCT is now under renovation by the Ibaraki prefectural government. We are tentatively calling this project 'I-BNCT' because of the Ibaraki prefectural sponsorship. Investigation of an 8
Non-linear and signal energy optimal asymptotic filter design
Josef Hrusak
2003-10-01
Full Text Available The paper studies some connections between the main results of the well known Wiener-Kalman-Bucy stochastic approach to filtering problems based mainly on the linear stochastic estimation theory and emphasizing the optimality aspects of the achieved results and the classical deterministic frequency domain linear filters such as Chebyshev, Butterworth, Bessel, etc. A new non-stochastic but not necessarily deterministic (possibly non-linear alternative approach called asymptotic filtering based mainly on the concepts of signal power, signal energy and a system equivalence relation plays an important role in the presentation. Filtering error invariance and convergence aspects are emphasized in the approach. It is shown that introducing the signal power as the quantitative measure of energy dissipation makes it possible to achieve reasonable results from the optimality point of view as well. The property of structural energy dissipativeness is one of the most important and fundamental features of resulting filters. Therefore, it is natural to call them asymptotic filters. The notion of the asymptotic filter is carried in the paper as a proper tool in order to unify stochastic and non-stochastic, linear and nonlinear approaches to signal filtering.
Sandeep Mukherjee
2012-11-01
Full Text Available Filters play an important role in most RF and Microwave applications. Currently, the electromagnetic spectrum is limited, and the applications are restricted to occupy just a portion of frequency range without affecting the equipment working out of band and also, without being affected by adjacent devices. Emerging applications such as wireless communications continue challenging RF/Microwave filters performance with even more stringent requirements, higher performance, smaller size, lighter weights, and low cost. Depending on the requirements and specifications, filters can mainly be designed with lumped or distributed elements. This paper describes the design of a newly proposed wide band micro strip band stop filter with open circuited stubs. This paper represents the design, simulation and fabrication of wideband bandstop filter using microstrip which is designed to have a center frequency of 2.5GHz. The filter is fabricated on a FR-4 substrate having dielectric constant
Design of FIR Filter Using Particle Swarm Optimization Algorithm for Audio Processing
Amanpreet Kaur
2012-08-01
Full Text Available In this paper, an optimal design of linear phase digital finiteimpulse response (FIR filter using Modified Particle SwarmOptimization (MPSO has been presented. In the designprocess, the filter length, pass band and stop band frequencies,pass band and stop band ripple sizes are specified. Sometimesthe gradient based optimization techniques are not effectivefor designing filter. An evolutionary method is introduced tofind the optimal solution of FIR filter design problem. MPSOis a global stochastic searching technique that can find out theglobal optima of the problem. A simulation results reveals theoptimization efficacy of the algorithm for the solution of,highly non-linear, and constrained filter design problems. Thedesigned filter is then applied on the audio application for upsampling of the audio signal. MATLAB toolkit functions areused for implementation of proposed algorithm.
All-Pole Recursive Digital Filters Design Based on Ultraspherical Polynomials
N. Stojanovic
2014-09-01
Full Text Available A simple method for approximation of all-pole recursive digital filters, directly in digital domain, is described. Transfer function of these filters, referred to as Ultraspherical filters, is controlled by order of the Ultraspherical polynomial, nu. Parameter nu, restricted to be a nonnegative real number (nu ≥ 0, controls ripple peaks in the passband of the magnitude response and enables a trade-off between the passband loss and the group delay response of the resulting filter. Chebyshev filters of the first and of the second kind, and also Legendre and Butterworth filters are shown to be special cases of these allpole recursive digital filters. Closed form equations for the computation of the filter coefficients are provided. The design technique is illustrated with examples.
Design of Reversible Multipliers for Linear Filtering Applications in DSP
Rakshith Saligram
2012-12-01
Full Text Available Multipliers in DSP computations are crucial. Thus modern DSP systems need to develop low power multipliers to reduce the power dissipation. One of the efficient ways to reduce power dissipation is by the use of bypassing technique. If a bit in the multiplier and/or multiplicand is zero the whole array of rowand/or diagonal will be bypassed and hence the name bypass multipliers. This paper presents the column Bypass multiplier and 2-D bypass multiplier using reversible logic; Reversible logic is a more prominent technology, having its applications in Low Power CMOS and quantum computations. The switching activity of any component in the bypass multiplier depends only on the input bit coefficients. The semultipliers find application in linear filtering FFT computational units, particularly during zero padding where there will be umpteen numbers of zeros. A bypass multiplier reduces the number of switching activities as well as the power consumption, above which reversible logic design acts to further almost nullify the dissipations
We present design optimization of wavelength filters based on long period waveguide gratings (LPWGs) using the adaptive particle swarm optimization (APSO) technique. We demonstrate optimization of the LPWG parameters for single-band, wide-band and dual-band rejection filters for testing the convergence of APSO algorithms. After convergence tests on the algorithms, the optimization technique has been implemented to design more complicated application specific filters such as erbium doped fiber amplifier (EDFA) amplified spontaneous emission (ASE) flattening, erbium doped waveguide amplifier (EDWA) gain flattening and pre-defined broadband rejection filters. The technique is useful for designing and optimizing the parameters of LPWGs to achieve complicated application specific spectra. (paper)
Sakurai, Yoshinori; Tanaka, Hiroki; Takata, Takushi; Fujimoto, Nozomi; Suzuki, Minoru; Masunaga, Shinichiro; Kinashi, Yuko; Kondo, Natsuko; Narabayashi, Masaru; Nakagawa, Yosuke; Watanabe, Tsubasa; Ono, Koji; Maruhashi, Akira
2015-07-01
At the Kyoto University Research Reactor Institute (KURRI), a clinical study of boron neutron capture therapy (BNCT) using a neutron irradiation facility installed at the research nuclear reactor has been regularly performed since February 1990. As of November 2014, 510 clinical irradiations were carried out using the reactor-based system. The world's first accelerator-based neutron irradiation system for BNCT clinical irradiation was completed at this institute in early 2009, and the clinical trial using this system was started in 2012. A shift of BCNT from special particle therapy to a general one is now in progress. To promote and support this shift, improvements to the irradiation system, as well as its preparation, and improvements in the physical engineering and the medical physics processes, such as dosimetry systems and quality assurance programs, must be considered. The recent advances in BNCT at KURRI are reported here with a focus on physical engineering and medical physics topics.
Generalized Design Method for Voltage-Controlled Current-Mode Multifunction Filters
I. Lattenberg
2009-11-01
Full Text Available In the article, the Generalized Current Follower Transconductance Amplifier (GCFTA element for generalized frequency filter design and a novel active element, the Programmable Current Amplifier (PCA for the realization of the current-mode analog blocks, are presented. The paper also presents a method of general frequency filter design, whereas the basic circuit is a general autonomous circuit using GCFTA, PCA elements and general admittances. The properties of the proposed filter have been verified using PSPICE simulations.
Min-Max Design of FIR Digital Filters by Semidefinite Programming
Nagahara, Masaaki
2011-01-01
In this article we consider two problems: FIR (Finite Impulse Response) approximation of IIR (Infinite Impulse Response) filters and inverse FIR filtering of FIR or IIR filters. By means of Kalman-Yakubovich-Popov (KYP) lemma and its generalization (GKYP), the problems are reduced to semidefinite programming described in linear matrix inequalities (LMIs). MATLAB codes for these design methods are given. An design example shows the effectiveness of these methods.
BNCT Technology Development on HANARO Reactor
So as to establish the biological effects of BNCT in the HANARO Reactor, biological damages in cells and animals with treatment of boron/neutron were investigated. And 124I-BPA animal PET image, analysis technology of the boron contents in the mouse tissues by ICP-AES was established. A Standard clinical protocol, a toxicity evaluation report and an efficacy investigation report of BNCT has been developed. Based on these data, the primary permission of clinical application was acquired through IRB of our hospital. Three cases of pre-clinical experiment for boron distribution and two cases of medium-sized animal simulation experiment using cat with verifying for 2 months after BNCT was performed and so the clinical demonstration with a patient was prepared. Also neutron flux, fast neutron flux and gamma ray dose of BNCT facility were calculated and these data will be utilized good informations for clinical trials and further BNCT research. For the new synthesis of a boron compound, o-carboranyl ethylamine, o-carboranylenepiperidine, o-carboranyl-THIQ and o-carboranyl-s-triazine derivatives were synthesized. Among them, boron uptake in the cancer cell of the triazine derivative was about 25 times than that of BPA and so these three synthesized methods of new boron compounds were patented
BNCT Technology Development on HANARO Reactor
Chun, Ki Jung; Park, Kyung Bae; Whang, Seung Ryul; Kim, Myong Seop
2007-06-15
So as to establish the biological effects of BNCT in the HANARO Reactor, biological damages in cells and animals with treatment of boron/neutron were investigated. And 124I-BPA animal PET image, analysis technology of the boron contents in the mouse tissues by ICP-AES was established. A Standard clinical protocol, a toxicity evaluation report and an efficacy investigation report of BNCT has been developed. Based on these data, the primary permission of clinical application was acquired through IRB of our hospital. Three cases of pre-clinical experiment for boron distribution and two cases of medium-sized animal simulation experiment using cat with verifying for 2 months after BNCT was performed and so the clinical demonstration with a patient was prepared. Also neutron flux, fast neutron flux and gamma ray dose of BNCT facility were calculated and these data will be utilized good informations for clinical trials and further BNCT research. For the new synthesis of a boron compound, o-carboranyl ethylamine, o-carboranylenepiperidine, o-carboranyl-THIQ and o-carboranyl-s-triazine derivatives were synthesized. Among them, boron uptake in the cancer cell of the triazine derivative was about 25 times than that of BPA and so these three synthesized methods of new boron compounds were patented.
Spectrum shaping of accelerator-based neutron beams for BNCT
Montagnini, B; Esposito, J; Giusti, V; Mattioda, F; Varone, R
2002-01-01
We describe Monte Carlo simulations of three facilities for the production of epithermal neutrons for Boron Neutron Capture Therapy (BNCT) and examine general aspects and problems of designing the spectrum-shaping assemblies to be used with these neutron sources. The first facility is based on an accelerator-driven low-power subcritical reactor, operating as a neutron amplifier. The other two facilities have no amplifier and rely entirely on their primary sources, a D-T fusion reaction device and a conventional 2.5 MeV proton accelerator with a Li target, respectively.
Radio Frequency Seeker Modelling and Seeker Filter Design
Prashant Vora
2005-07-01
Full Text Available Radio frequency seeker model, including receiver angle error noise modelling and filtering of noise from seeker measurement, is presented in this paper. The effects of eclipsing, radar cross section fluctuation, etc on seeker sight-line rate measurement are highlighted. The formulation for colour noise modelling of sight-line rate noise is derived based on the knowledge of seeker receiver angle error noise model. Two Kalman filter configurations for filtering of noise from seeker output have been considered in this paper, based on sight-line rate kinematics and noise characteristic. It has been observed from the simulation studies that sight-line rate signal varies slowly at higher interceptor-target ranges; with severe colour noise in sight line rate measurement, and therefore higher weightage for noise attenuation is beneficial in Kalman filter configuration. So, kinematic plus state augmentation for colour noise are considered for adequate filtering for higher interceptor-target ranges. Whereas for lower interceptor-target ranges, sight-line rate changes appreciably, which have been tracked by a simplified/modified spherical coordinate model, which uses knowledge of interceptor-target engagement dynamics. For both the filters, benefits of colour noise modelling and process model augmentation through coloured noise states, for filtering severe colour noise of seeker, has been demonstrated.
Designing Microstrip Low Pass Filter In ISM Band For Rectenna System
Pavan Sharma
2012-08-01
Full Text Available The filter is required in all RF-communication techniques. Low Pass Filters play an important role in wireless power transmission systems. Transmitted and received signals have to be filtered at a certain frequency with a specific bandwidth. In this paper the design of filter is done in the ISM (Industrial, Scientific and Medical band whose frequency lies between 1.55GHz- 3.99GHz. After getting the specifications required, we realized the filter structure with the help of CST-MW software.
Line filter design of parallel interleaved VSCs for high power wind energy conversion systems
Gohil, Ghanshyamsinh Vijaysinh; Bede, Lorand; Teodorescu, Remus; Kerekes, Tamas; Blaabjerg, Frede
2015-01-01
for the two parallel interleaved VSCs is derived in order to obtain the worst case voltage magnitude of the individual harmonic components. The required value of the filter admittance for the specific harmonic component is obtained by using the worst case voltage magnitude and the allowable harmonic...... injection limit. In order to achieve the desired filter performance with optimal values of the filter parameters, the use of a LC trap branch with the conventional LCL filter is proposed. The expressions for the resonant frequencies of the proposed line filter are derived and used in the design to...
Software Engineering-Based Design for a Bayesian Spam Filter
Mumtaz Mohammed Ali AL-Mukhtar
2010-01-01
The rapid spread and the easy availability of a free e-mail service have made it the medium of choice for the sending of unsolicited advertising and bulk e-mail in general. These messages, known as junk e-mail or spam mail, are an increasing problem to both Internet users and Internet service providers (ISPs). The research resolves one aspect of the spam problem by developing an appropriate filter for the e-mail client. The proposed filter is a combination of three forms of filters: Whitelist...
Design of Microstrip Band Pass Fractal Filter for Suppression of Spurious Band
P. K. Singhal
2008-12-01
Full Text Available In this paper, the design and subsequent fabrication of a hairpin-line band pass filter has been proposed. This filter exhibits periodic frequency response. By proper design, the spurious bands are being suppressed significantly through the implementation of Koch fractal on the microstrip coupled line.
New optimal design method for trap damping sections in grid-connected LCL filters
Beres, Remus Narcis; Wang, Xiongfei; Blaabjerg, Frede;
2014-01-01
A straightforward method is proposed in this paper to optimally design the damping sections of the LCL or LCL plus trap filters. The proposed method simplifies the iterative design procedure of the overall filter while ensuring minimum resonance peaking and smaller capacitor than otherwise would ...
The time-of-flight epithermal neutron spectrum measurement from accelerator based BNCT facility
Results of epithermal neutrons spectrum measurement by time-of-flight method for different beam shaping assembly designed for BNCT purposes are presented. Discuss method to realize time-of-flight measurement at accelerator. Results looks are important for beam shaping assembly optimization and accurate and reliable treatment planning. (author)
Design and Simulation of Edge-Coupled Stripline Band Pass Filter for U band
Pawan Shakdwipee
2013-08-01
Full Text Available In this paper, a band pass filter structure using Ansoft designer software and Matlab software simulation tool are presented. The filter is operated at U Band range in higher order 50 GHz edge-coupled Stripline band pass filter for different microwave application. For the proposed work we consider simulation using Roger R03203 substrate with dielectric constant of 3.02, Conductor Thickness 0.035 mm and Substrate Height 0.787 mm. This filter is design at a center frequency of 50 GHz with 8 GHz bandwidth. Simulation results show that the filter operation is optimum and best in this range and results show good performance and agree well with the high frequency EM full wave simulation. In this paper, band pass filter development with the assistance of the Richards-Kuroda Transformation method, is used. Moreover, measured S parameters denote the center frequency is also strongly influenced by the variation of Roger's material's dielectric constants. By analyzing the characteristics at center frequency of the filter, both theoretical and simulated data are accumulated for broadening application filed. The band pass filter exhibits advantages of small size and high reliability compared to conventional planar filter structure, which makes the band pass filter suitable for U Band communicational application. This filter shows attractive characteristics for BPF applications.
A Top-Down Optimization Methodology for SC Filter Circuit Design Using Varying Goal Specifications
Serra, Hugo; Santos-Tavares, Rui; Paulino, Nuno
2014-01-01
Part 19: Electronics: Design International audience The design of Switched-Capacitor (SC) filters can be an arduous process, which becomes even more complex when the high gain amplifier is replaced by a low gain amplifier or a voltage follower. This eliminates the virtual ground node, requiring the compensation of the parasitic capacitances during the design phase. This paper proposes an automatic procedure for the design of SC filters using low gain amplifiers, based on a Genetic Algor...
The design of digital all-pass filters using second-order cone programming (SOCP)
Chan, SC; Chen, HH; Pun, CKS
2005-01-01
This brief proposes a new method for designing digital all-pass filters with a minimax design criterion using second-order cone programming (SOCP). Unlike other all-pass filter design methods, additional linear constraints can be readily incorporated. The overall design problem can be solved through a series of linear programming subproblems and the bisection search algorithm. The convergence of the algorithm is guaranteed. Nonlinear constraints such as the pole radius constraint of the filte...
Design of Super-resolution Filters with a Gaussian Beam in Optical Data Storage Systems
Super-resolution filters based on a Gaussian beam are proposed to reduce the focusing spot in optical data storage systems. Both of amplitude filters and pure-phase filters are designed respectively to gain the desired intensity distributions. Their performances are analysed and compared with those based on plane wave in detail. The energy utilizations are presented. The simulation results show that our designed super-resolution filters are favourable for use in optical data storage systems in terms of performance and energy utilization
Design and Simulation of Edge-Coupled Stripline Band Pass Filter for U band
Pawan Shakdwipee
2013-01-01
In this paper, a band pass filter structure using Ansoft designer software and Matlab software simulation tool are presented. The filter is operated at U Band range in higher order 50 GHz edge-coupled Stripline band pass filter for different microwave application. For the proposed work we consider simulation using Roger R03203 substrate with dielectric constant of 3.02, Conductor Thickness 0.035 mm and Substrate Height 0.787 mm. This filter is design at a center frequency of 50 GHz with 8 GHz...
A Robust Filter Design for Uncertain Singular Systems with Unreliable Channels
Ching-Min Lee
2011-06-01
Full Text Available This paper considers the problem of robust H_∞ filter design in uncertain discrete-time singular systems with possible missing measurements due to unreliable network transmission channels. The stochastic variable satisfying Bernoulli random binary distribution is introduced to model the missing phenomena and the corresponding filtering error dynamics with delay is then induced. We provide a set of sufficient conditions for the existence of the desired filter, and propose a robust filter design method under a strict linear matrix inequality framework. A numerical example is given to illustrate the effectiveness of the proposed method
Effect of the Design Parameters on the Performance of Inner Recycling Continuous Sand Filter
CHEN Zhi-qiang; WEN Qin-xue; Lü Bing-nan
2002-01-01
A novel integrated water treatment facility, innerrecycling continuous sand filter, is discussed. The theory of micro-flocculation is applied in the sand-washing circulation system with continuous filtration and backwashing. The design and operation parameters,which affect the performance of the filter, are discussed.The key design parameters are provided as follows:diameter of filter material is 0.7 to 1.0 mm, depth of filter bed is 0.6 m, filtration velocity is less than 12 m/h,ratio of gas to water is 9:11 and sand recycling rate is 2 to 4 mm/min.
BNCT for malignant brain tumors in children
BSH-based intra-operative BNCT as an initial treatment underwent in 4 children with malignant brain tumors since 1998. There were 2 glioblastomas, one primitive neuroectodermal tumor (PNET) and one anaplastic ependymoma patient. They included two children under 3-year-old. All GBM patients were died of CSF dissemination without tumor regrowth in the primary site. Another PNET and anaplastic ependymoma patients are still alive without tumor recurrence. We can consider BNCT is optimal treatment modality for malignant brain tumor in children. (author)
Production of epithermal neutron beams for BNCT
Bisceglie, E; Colonna, N; Paticchio, V; Santorelli, P; Variale, V
2002-01-01
The use of boron neutron capture therapy (BNCT) for the treatment of deep-seated tumors requires neutron beams of suitable energy and intensity. Simulations indicate the optimal energy to reside in the epithermal region, in particular between 1 and 10 keV. Therapeutic neutron beams with high spectral purity in this energy range could be produced with accelerator-based neutron sources through a suitable neutron-producing reaction. Herein, we report on different solutions that have been investigated as possible sources of epithermal neutron beams for BNCT. The potential use of such sources for a hospital-based therapeutic facility is discussed.
Effect of shaped filter design on dose and image quality in breast CT
The purpose of this study was to investigate the effect of shaped filters specifically designed for dedicated breast computed tomography (CT) scanners on dose and image quality. Optimization of filter shape and material in fan direction was performed using two different design methods, one aiming at homogeneous noise distributions in the CT images and the other aiming at a uniform dose distribution in the breast. The optimal filter thickness as a function of fan angle was determined iteratively to fulfil the above mentioned criteria for each breast diameter. Different filter materials (aluminium, copper, carbon, polytetrafluoroethylene) and breast phantoms with diameters between 80–180 mm were investigated. Noise uniformity in the reconstructed images, obtained from CT simulations based on ray-tracing methods, and dose in the breast, calculated with a Monte Carlo software tool, were used as figure of merit. Furthermore, CT-value homogeneity, the distribution of noise in cone direction, spatial resolution from centre to periphery and the contrast-to-noise ratio weighted by dose (CNRD) were evaluated. In addition, the decrease of scatter due to shaped filters was investigated. Since only few or one filter are practical in clinical CT systems, the effects of one shaped filter for different breast diameters were also investigated. In this case the filter, designed for the largest breast diameter, was simulated at variable source-to-filter distances depending on breast diameter. With the filter design method aiming at uniform noise distribution best results were obtained for aluminium as the filter material. Noise uniformity improved from 20% down to 5% and dose was reduced by about 30–40% for all breast diameters. No decrease of noise uniformity in cone direction, CT-value homogeneity, spatial resolution and the CNRD was detected with the shaped filter. However, a small improvement of CNRD was observed. Furthermore, a scatter reduction of about 20–30% and a more
On the Polyphase Decomposition for Design of Generalized Comb Decimation Filters
Laddomada, Massimiliano
2007-01-01
Generalized comb filters (GCFs) are efficient anti-aliasing decimation filters with improved selectivity and quantization noise (QN) rejection performance around the so called folding bands with respect to classical comb filters. In this paper, we address the design of GCF filters by proposing an efficient partial polyphase architecture with the aim to reduce the data rate as much as possible after the Sigma-Delta A/D conversion. We propose a mathematical framework in order to completely characterize the dependence of the frequency response of GCFs on the quantization of the multipliers embedded in the proposed filter architecture. This analysis paves the way to the design of multiplier-less decimation architectures. We also derive the impulse response of a sample 3rd order GCF filter used as a reference scheme throughout the paper.
Resilient Minimum Entropy Filter Design for Non-Gaussian Stochastic Systems
Lei Guo; Hong Wang; Yan Wang
2013-01-01
In this paper, the resilient minimum entropy filter problem is investigated for the stochastic systems with non-Gaussian disturbances. The goal of designing the filter is to guarantee that the entropy of the estimation error is monotonically decreasing, moreover, the error system is exponentially ultimately bounded in the mean square. Based on the entropy performance function, a filter gain updating algorithm is presented to make the entropy decrease at every sampling instant k. Then the boun...
Designing a Microwave Filter by Studying and Simulating the Discontinuity in the Waveguide
Ghafir Ibrahim; Přenosil Václav
2013-01-01
This research aims to design a microwave filter by studying and simulating the discontinuity in the waveguide. We suggest a filter consists of three waveguides connected to each other and different dimensions. Changing the dimensions of the waveguide will change the conditions of propagation of microwaves and in our suggested filter we have two discontinuity regions affecting on the modes of frequencies propagated through the waveguide. We apply Galerkin method for studying the discontinuity ...
Design and Efficiency Analysis of one Class of Uniform Linear Phase FIR Filter Banks
R. D. Pantić
2013-11-01
Full Text Available One class of uniform linear phase filter banks with different numbers of band-pass channels will be considered in this study, concentrating on 5, 9 and 17-band filter banks and their mutual comparison concerning delay and implementation complexity. Designed banks are based on the FIR filters and frequency response masking technique and are also compared to the banks with direct realization considering complementarity and delay.
Performance and environmental characteristics of a compact, high-capacity HEPA filter design
An improved version of the HEPA filter has been developed and evaluated for conformity with MIL-51068. In this design, the filter paper (conforming to MIL-F-51079) is pleated to a depth of only 18 mm. Ribbons essentially the same material as the filter paper form inter-pleat spacers, providing a crest-to-crest spacing of 3 mm. The resultant filter has the same DOP penetration level as the standard MIL-F-51068 HEPA filter, but about half its pressure drop at the same airflow. Materials of construction, adhesives, gaskets and faceguards match MIL-f-51068. Both flat-panel and zig-zag configurations of the filter meet the rough handling test of MIL-F-51068. Preliminary indications are that both filters will meet the overpressure tests of MIL-F-51068D and the flammability requirements of UL 586; these tests are in progress. Filters can be supplied to interchange with existing HEPA filter sizes. The improved pressure drop characteristic of these filters can be used to provide longer intervals between filter changes, or equal life at greater capacity
Neutron and photon fields in the BNCT room with closed beam shutters
The epithermal neutron beam at the LVR-15 reactor was designed for the Boron Neutron Capture Therapy (BNCT) of cancers, but it has also been used for material testing. In the case where the beam is closed with two designed shutters, there is still an indispensable background in the irradiation room, which limits the movement of persons during patient positioning before exposure or during the preparation of the samples. Because the epithermal filter of the beam was designed in a former thermal column, as a multi-layer system, it was suspected that both fast neutrons and photons penetrated the filter shielding into the room. The purpose of this study was to determine the causes of potential faulty shielding and to estimate the doses to persons who perform the irradiation experiments and/or exposure of patients. The quality of the shielding was evaluated from two-dimensional measurements of both neutron and photon distribution on the surface of the beam shutter. During the measurement both the shutters of the epithermal beam were closed and the reactor was operated at the nominal power of 9 MW. This experimental arrangement is similar to the conditions that exist when either the irradiation experiments or the exposure of patients is performed in this room. The neutron space distribution was measured using a Bonner sphere of φ 76.2 mm diameter with an LiI(Tl) scintillation detector of φ 4 x 8 mm. A small Geiger-Muller tube was used for the measurement of photon distribution. The detectors were placed on a three-dimensional positioning equipment controlled by a computer, which enabled automatic measurement with 1 cm mesh step. Results of the measurement show that the background profile in the irradiation room has reasonable maximum only at the beam aperture. Published by Univ. of Press. All rights reserved. (authors)
Characteristics of the new THOR epithermal neutron beam for BNCT
A characterization of the new Tsing Hua open-pool reactor (THOR) epithermal neutron beam designed for boron neutron capture therapy (BNCT) has been performed. The facility is currently under construction and expected in completion in March 2004. The designed epithermal neutron flux for 1 MW power is 1.7x109 n cm-2 s-1 in air at the beam exit, accompanied by photon and fast neutron absorbed dose rates of 0.21 and 0.47 mGy s-1, respectively. With 10B concentrations in normal tissue and tumor of 11.4 and 40 ppm, the calculated advantage depth dose rate to the modified Snyder head phantom is 0.53 RBE-Gy min-1 at the advantage depth of 85 mm, giving an advantage ratio of 4.8. The dose patterns determined by the NCTPlan treatment planning system using the new THOR beam for a patient treated in the Harvard-MIT clinical trial were compared with results of the MITR-II M67 beam. The present study confirms the suitability of the new THOR beam for possible BNCT clinical trials
Hintzen, E.; Vennemann, T.; Mathis, W.
2014-11-01
In this paper a new filter design concept is proposed and implemented which takes into account the complex loudspeaker impedance. By means of techniques of broadband matching, that has been successfully applied in radio technology, we are able to optimize the reconstruction filter to achieve an overall linear frequency response. Here, a passive filter network is inserted between source and load that matches the complex load impedance to the complex source impedance within a desired frequency range. The design and calculation of the filter is usually done using numerical approximation methods which are known as Real Frequency Techniques (RFT). A first approach to systematic design of reconstruction filters for class-D amplifiers is proposed, using the Simplified Real Frequency Technique (SRFT). Some fundamental considerations are introduced as well as the benefits and challenges of impedance matching between class-D amplifiers and loudspeakers. Current simulation data using MATLAB is presented and supports some first conclusions.
Design of generalised orthogonal filters: application to the modelling of dynamical systems
Nikolić, Saša S.; Antić, Dragan S.; Perić, Staniša Lj.; Danković, Nikola B.; Milojković, Marko T.
2016-02-01
In this article, we define a new class of orthogonal filters with complex poles and zeroes inside their transfer function. This further improvement of classical orthogonal filters allows the possibility to model a wider range of real systems, that is, the systems whose mathematical models have complex zeroes besides real ones. These filters can be applied in the following areas: circuit theory, telecommunications, signal processing, bond graphs, theory approximations and control system theory. First, we describe the rational functions with complex poles and zeroes, and prove their orthogonality. Based on these functions, we designed the block diagram of orthogonal Legendre-type filter with complex poles and zeroes. After that an appropriate analogue scheme of this filter for practical realisation is derived. To validate theoretical results, we performed an experiment with a cascade-connected system designed and practically realised in our laboratories. The experiments proved the quality of the designed orthogonal model in terms of accuracy and simplicity.
Clinical results of boron neutron capture therapy (BNCT) for glioblastoma
The purpose of this study was to evaluate the clinical outcome of BSH-based intra-operative BNCT (IO-BNCT) and BSH and BPA-based non-operative BNCT (NO-BNCT). We have treated 23 glioblastoma patients with BNCT without any additional chemotherapy since 1998. The median survival time (MST) of BNCT was 19.5 months, and 2-year, 3-year and 5-year survival rates were 26.1%, 17.4% and 5.8%, respectively. This clinical result of BNCT in patients with GBM is superior to that of single treatment of conventional radiotherapy compared with historical data of conventional treatment. - Highlights: ► In this study, we evaluate the clinical outcome of boron neutron capture therapy (BNCT) for malignant brain tumors. ► We have treated 23 glioblastoma (GBM) patients with BNCT without any additional chemotherapy. ► Clinical results of BNCT in patients with GBM are superior to that of single treatment of conventional radiotherapy compared with historical data of conventional treatment.
Computer aided design of reentrant coaxial filters including coaxial excitation
Boria, V.; Gerini, G.; Guglielmi, M.
1999-01-01
An advanced EM based CAD tool is used for the detailed characterisation of a family of reentrant coaxial waveguide filters. The EM analysis includes the effects of tuning screws and of the input/output coaxial excitation. The software is essentially used as an efficient replacement for the tradition
INEL BNCT Program: Volume 5, No. 9
Ackermann, A.L. (ed.)
1991-01-01
This Bulletin presents a summary of accomplishments and highlights of the Idaho National Engineering Laboratory's (INEL) Boron Neutron Capture Therapy (BNCT) Program for September 1991. This bulletin includes information on the brain tumor and melanoma research programs, Power Burst Facility (PBF) technical support and modifications, PBF operations, and updates to the animal data charts.
Introducing BNCT treatment in new treatment facilities
The physical and radiobiological studies that should be performed before the initiation of BNCT are discussed. The need for dose-escalation versus response studies in large animal models is questioned. These studies are time consuming, expensive and legally difficult in some countries and may be dispensable. (author)
Optimal design and performance verification of a broadband waveguide filter using ANN-GA algorithm
Manidipa Nath
2013-09-01
Full Text Available In this work design and optimization of EBGstructure having multiple dielectric posts uniformly placed insidea rectangular waveguide is done to extract filter responses.Frequency response of BPF configuration using trained ANNmodel of multipost rectangular waveguide are studied andoptimized using GA. The geometrical and positional dimensionof post parameters are varied in accordance to the requirementof reflectance and transmittance of the filter.
Optimal design and performance verification of a broadband waveguide filter using ANN-GA algorithm
Manidipa Nath; Sudhabindu Ray; Bhaskar Gupta
2013-01-01
In this work design and optimization of EBGstructure having multiple dielectric posts uniformly placed insidea rectangular waveguide is done to extract filter responses.Frequency response of BPF configuration using trained ANNmodel of multipost rectangular waveguide are studied andoptimized using GA. The geometrical and positional dimensionof post parameters are varied in accordance to the requirementof reflectance and transmittance of the filter.
Design of efficient circularly symmetric two-dimensional variable digital FIR filters.
Bindima, Thayyil; Elias, Elizabeth
2016-05-01
Circularly symmetric two-dimensional (2D) finite impulse response (FIR) filters find extensive use in image and medical applications, especially for isotropic filtering. Moreover, the design and implementation of 2D digital filters with variable fractional delay and variable magnitude responses without redesigning the filter has become a crucial topic of interest due to its significance in low-cost applications. Recently the design using fixed word length coefficients has gained importance due to the replacement of multipliers by shifters and adders, which reduces the hardware complexity. Among the various approaches to 2D design, transforming a one-dimensional (1D) filter to 2D by transformation, is reported to be an efficient technique. In this paper, 1D variable digital filters (VDFs) with tunable cut-off frequencies are designed using Farrow structure based interpolation approach, and the sub-filter coefficients in the Farrow structure are made multiplier-less using canonic signed digit (CSD) representation. The resulting performance degradation in the filters is overcome by using artificial bee colony (ABC) optimization. Finally, the optimized 1D VDFs are mapped to 2D using generalized McClellan transformation resulting in low complexity, circularly symmetric 2D VDFs with real-time tunability. PMID:27222739
Equalization of Loudspeaker and Room Responses Using Kautz Filters: Direct Least Squares Design
Tuomas Paatero
2007-01-01
Full Text Available DSP-based correction of loudspeaker and room responses is becoming an important part of improving sound reproduction. Such response equalization (EQ is based on using a digital filter in cascade with the reproduction channel to counteract the response errors introduced by loudspeakers and room acoustics. Several FIR and IIR filter design techniques have been proposed for equalization purposes. In this paper we investigate Kautz filters, an interesting class of IIR filters, from the point of view of direct least squares EQ design. Kautz filters can be seen as generalizations of FIR filters and their frequency-warped counterparts. They provide a flexible means to obtain desired frequency resolution behavior, which allows low filter orders even for complex corrections. Kautz filters have also the desirable property to avoid inverting dips in transfer function to sharp and long-ringing resonances in the equalizer. Furthermore, the direct least squares design is applicable to nonminimum-phase EQ design and allows using a desired target response. The proposed method is demonstrated by case examples with measured and synthetic loudspeaker and room responses.