WorldWideScience
1

?2 integrins are required for skin homing of primed T cells but not for priming naive T cells  

UK PubMed Central (United Kingdom)

b2;2 integrins are of critical importance for leukocyte extravasation through vascular endothelia and for T cell activation. To elucidate the role of b2;2 integrins...Full Text Available

2002-01-15

2

Transforming growth factor-?1 induces intestinal myofibroblast differentiation and modulates their migration  

UK PubMed Central (United Kingdom)

AIM: To investigate the effects of transforming growth factor b2;1 (TGF-b2;1) on the differentiation of colonic lamina propria fibroblasts (CLPF) into myofibroblasts in vitro.METHODS:...Full Text Available

2009-03-28

3

The Pseudoreceptor BMP and Activin Membrane-bound Inhibitor Positively Modulates Wnt/?-Catenin Signaling*  

UK PubMed Central (United Kingdom)

The canonical Wnt/b2;-catenin pathway plays a pivotal role in regulating embryogenesis and tumorigenesis by promoting cell proliferation. BAMBI (BMP and activin membrane-bound inhibitor) has...Full Text Available

2008-11-28

6

Tissue structure, nuclear organization and gene expression in normal and malignant breast  

Energy Technology Data Exchange (ETDEWEB)

Because every cell within the body has the same genetic information, a significant problem in biology is to understand how cells within a tissue express genes selectively. A sophisticated network of physical and biochemical signals converge in a highly orchestrated manner to bring about the exquisite regulation that governs gene expression in diverse tissues. Thus, the ultimate decision of a cell to proliferate, express tissue-specific genes, or apoptose must be a coordinated response to its adhesive, growth factor, and hormonal milieu. The unifying hypothesis examined in this overview is that the unit of function in higher organisms is neither the genome nor the cell alone but the complex, three-dimensional tissue. This is because there are bidirectional connections between the components of the cellular microenvironment (growth factors, hormones, and extracellular matrix) and the nucl2048 These connections are made via membrane-bound receptors and transmitted to the nucleus, where ...

2000-01-27

7

Interaction of ?V?3 and ?V?6 Integrins with Human Parechovirus 1?  

UK PubMed Central (United Kingdom)

Human parechovirus (HPEV) infections are very common in early childhood and can be severe in neonates. It has been shown that integrins are important for cellular infectivity of HPEV1 through experiments...Full Text Available

2010-09-01

8

Extracellular Protein Disulfide Isomerase Regulates Feedback Activation of Platelet Thrombin Generation Via Modulation of Coagulation Factor Binding.  

Science.gov (United States)

Background: Protein disulfide isomerase (PDI) controls platelet integrin function, tissue-factor (TF) activation, and concentrates at fibrin and thrombus formation sites of vascular injury. Objective: We investigated involvement of surface thiol isomerases and especially PDI, in thrombin-mediated thrombin amplification on human platelets. Methods/Results: Using a new developed thrombin-dependent platelet thrombin generation assay we observed that the feedback activation of thrombin generation on the platelet surface does not depend on TF, as anti-TF antibodies inhibiting TF-induced thrombin formation in platelet-depleted plasma had no effect compared to vehicle-treated controls. Feedback activation of thrombin generation in the presence of platelets was significantly diminished by membrane impermeant thiol blockers or by the thiol isomerase-inhibitors bacitracin and anti-PDI antibody RL90, respectively. Platelet thrombin formation depends on binding of coagulation ...

2011-09-19

9

The inhibition of tumor cell intravasation and subsequent metastasis through the regulation of in vivo tumor cell motility by the tetraspanin CD151  

UK PubMed Central (United Kingdom)

SummaryIn vivo tumor cell migration through integrin-dependent pathways is key to the metastatic behavior of malignant cells. Using quantitative in vivo...Full Text Available

2008-03-01

10

Identification of Human Prostate Cancer Stem Cells by ...  

Science.gov (United States)

... The basal markers CK5, alpha 6 integrin (CD49f), CD44, and p63 were strongly expressed by the majority of sphere-forming cells. ... p63 p63 PSCA ...

2008-04-01

11

Effects of an Alpha-4 Integrin Inhibitor on Restenosis in a New Porcine Model Combining Endothelial Denudation and Stent Placement  

UK PubMed Central (United Kingdom)

Restenosis remains the main complication of balloon angioplasty and/or stent implantation. Preclinical testing of new pharmacologic agents preventing restenosis largely rely on porcine models, where...Full Text Available

12

Study on the crystallization behaviour and thermal stability of glass-ceramics used as solid oxide fuel cell-sealing materials  

British Library Electronic Table of Contents (United Kingdom)

Glass ceramics are commonly used as sealing materials for planar solid oxide fuel cells (SOFCs). The major requirements of stack and module builders for these materials are the stability of the coefficient of thermal expansion (CTE), excellent bonding (sticking) behaviour and the absence of volatile ingredients, which can lead to changes of the material properties and the sealing ability. SCHOTT Electronic Packaging has developed special glasses and glass-ceramics for various solid oxide fuel cell designs and operating temperatures. The glass compositions are based on the system MgO-Al2O3-BaO-SiO2-B2O3. In this study the evaluation of the developed materials was done by high temperature aging tests for up to 1000h, high temperature XRD-studies and Rietveld calculations, combined with scann...

2011-01-01

14

Use of integrin-linked kinase to extend function of encapsulated pancreatic tissue  

Energy Technology Data Exchange (ETDEWEB)

We have studied the impact of overexpression of an intracellular signaling protein, integrin-linked kinase (ILK), on the survival and function of encapsulated islet tissue used for the treatment of type 1 diabetes. The dimensions of the encapsulated tissue can impact the stresses placed on the tissue and ILK overexpression shows the ability to extend function of dissociated cells as well as intact islets. These results suggest that lost cell-extracellular matrix interactions in cell encapsulation systems can lead to decreased insulin secretion and ILK signaling is a target to overcome this phenomenon. (communication)

2010-12-15

15

Test de levage module QRL  

CERN Multimedia

Test de levage module QRL

2004-01-01

16

All focused ion beam fabricated MgB_2 inter-grain nanobridge dc SQUIDs  

International Nuclear Information System (INIS)

We have fabricated MgB_2 dc SQUIDs (superconducting quantum interference devices) containing inter-grain nanobridges as Josephson elements by a focused ion beam (FIB) etching method and measured their transport properties. The entire structure including the SQUID loop was patterned only using a FIB. The beam energy was 30 kV and the current was 0.9 nA for larger structures and 34 and 1.5 pA for the nanobridge pattern. Each bridge with a nominal width of 100 nm crossed a single grain boundary in the normal direction. The SQUID loop had a 3.1 #mu#m x 3.1 #mu#m hole with a 2 #mu#m average linewidth, corresponding to an inductance of 5.1 pH. The nanobridges had a two-step transition with an increase in the resistivity of more than a decade and a substantial decrease in the critical current density. Current-voltage characteristics showed a resistively shunted junction behavior at all temperatures below T_c, which implies that the current in the ...

2009-06-01

17

B-1 Primary Safety  

Science.gov (United States)

... Page 2. Boston Scientific CRM 11/17/09 MADIT-CRT Clinical Report APPENDIX B 2 CONFIDENTIAL ... B-2 Primary Effectiveness B-2.1 Validation of Assumptions ...

18

Neuropilin-1/GIPC1 Signaling Regulates ?5?1 Integrin Traffic and Function in Endothelial Cells  

UK PubMed Central (United Kingdom)

Neuropilin 1 (Nrp1) is a coreceptor for vascular endothelial growth factor A165 (VEGF-A165, VEGF-A164 in mice) and semaphorin 3A (SEMA3A). Nevertheless, Nrp1 null embryos display vascular...Full Text Available

2009-01-01

19

Role of B2 Adrenergic Receptors in Labor Pain  

Science.gov (United States)

Pain; Pain Threshold; Labour Pain

2010-10-01

20

Cellular Sources of Transforming Growth Factor-? Isoforms in Early and Chronic Radiation Enteropathy  

UK PubMed Central (United Kingdom)

The three mammalian transforming growth factor (TGF)-b2; isoforms (TGF-b2;1, TGF-b2;2, and TGF-b2;3) differ in their putative roles in radiation-induced fibrosis in intestine...Full Text Available

1998-11-01

21

Development of a business-to-business critical success factors (B2B CSFs) framework for Chinese SMEs  

British Library Electronic Table of Contents (United Kingdom)

Purpose - The purpose of this paper is to critically explore business-to-business critical success factors (B2B CSFs) for small and medium-sized enterprises (SMEs) operating in the Chinese B2B marketplace, evaluate the findings, and use the generated CSFs to propose a framework to assist in the marketing management of B2B in China. The proposed framework provides a guideline for academics and practitioners and highlights the significant role of each factor in developing and sustaining effective B2B electronic commerce (B2B e-commerce) practice for SMEs. Design/methodology/approach - The proposed framework is constructed by combining the empirical findings and B2B literature. The quantitative (online survey) was targeted at, proprietors, ...

2011-01-01

22

Detection of constitutive heterodimerization of the integrin Mac-1 subunits by fluorescence resonance energy transfer in living cells  

International Nuclear Information System (INIS)

Macrophage differentiation antigen associated with complement three receptor function (Mac-1) belongs to #beta#_2 subfamily of integrins that mediate important cell-cell and cell-extracellular matrix interactions. Biochemical studies have indicated that Mac-1 is a constitutive heterodimer in vitro. Here, we detected the heterodimerization of Mac-1 subunits in living cells by means of two fluorescence resonance energy transfer (FRET) techniques (fluorescence microscopy and fluorescence spectroscopy) and our results demonstrated that there is constitutive heterodimerization of the Mac-1 subunits and this constitutive heterodimerization of the Mac-1 subunits is cell-type independent. Through FRET imaging, we found that heterodimers of Mac-1 mainly localized in plasma membrane, perinuclear, and Golgi area in living cells. Furthermore, through analysis of the estimated physical distances between cyan fluorescent protein (CFP) and yellow fluorescent protein (YFP) fused ...

2006-08-04

23

Bacterial Pili exploit integrin machinery to promote immune activation and efficient blood-brain barrier penetration.  

Science.gov (United States)

Group B Streptococcus (GBS) is the leading cause of meningitis in newborn infants. Bacterial cell surface appendages, known as pili, have been recently described in streptococcal pathogens, including GBS. The pilus tip adhesin, PilA, contributes to GBS adherence to blood-brain barrier (BBB) endothelium; however, the host receptor and the contribution of PilA in central nervous system (CNS) disease pathogenesis are unknown. Here we show that PilA binds collagen, which promotes GBS interaction with the ?(2)?(1) integrin resulting in activation of host chemokine expression and neutrophil recruitment during infection. Mice infected with the PilA-deficient mutant exhibit delayed mortality, a decrease in neutrophil infiltration and bacterial CNS dissemination. We find that PilA-mediated virulence is dependent on neutrophil influx as neutrophil depletion results in a decrease in BBB permeability and GBS-BBB penetration. Our results suggest that the bacterial pilus, ...

2011-09-06

24

Spatially resolved IR absorption spectroscopy by optical Stark modulation  

Energy Technology Data Exchange (ETDEWEB)

The first application of optical Stark modulation has been applied to measure spatially precise Stark-modulated IR absorption spectra in a flame.

1982-12-01

25

The biosynthesis of rubber from ?-hydroxy-?-methylglutaryl-coenzyme A in Hevea brasiliensis latex  

UK PubMed Central (United Kingdom)

1. b2;-Hydroxy-b2;-methyl[3-14C]glutaryl-CoA is efficiently incorporated into rubber on incubation with Hevea brasiliensis latex, and the incorporation is diminished...Full Text Available

1969-09-01

26

Physicochemical Characterization of Berberine Chloride: A Perspective in the Development of a Solution Dosage Form for Oral Delivery  

UK PubMed Central (United Kingdom)

The objective of the present research was to evaluate the physicochemical characteristics of berberine chloride and to assess the complexation of drug with 2-hydroxypropyl-b2;-cyclodextrin (HPb2;CD),...Full Text Available

27

Effects of ?-Cyclodextrin on the Structure of Sphingomyelin/Cholesterol Model Membranes  

UK PubMed Central (United Kingdom)

The interaction of b2;-cyclodextrin (b2;-CD) with mixed bilayers composed of sphingomylein and cholesterol (Chol) above and below the accepted stable complexation...Full Text Available

2010-09-08

28

The Effects of ?-Helical Structure and Cyanylated Cysteine on Each Other  

UK PubMed Central (United Kingdom)

b2;-Thiocyanatoalanine, or cyanylated cysteine, is an artificial...Full Text Available

2010-04-15

30

The K3 Fragment of Amyloidogenic ?2-Microglobulin Forms Ion Channels: Implication for Dialysis Related Amyloidosis  

UK PubMed Central (United Kingdom)

b2;2-microglobulin (b2;2m) amyloid deposits are linked to dialysis related amyloidosis (DRA) in hemodialysis patients. The mechanism by which b2;2m...Full Text Available

2009-10-21

31

Specific Sequence Motif of 8-Cys Repeats of TGF-? Binding Proteins, LTBPs, Creates a Hydrophobic Interaction Surface for Binding of Small Latent TGF-?  

UK PubMed Central (United Kingdom)

Transforming growth factor (TGF)-b2;s are secreted in large latent complexes consisting of TGF-b2;, its N-terminal latency-associated peptide (LAP) propeptide, and latent TGF-b2;...Full Text Available

2000-08-01

32

Molecular and functional characterization of a novel chromoplast-specific lycopene ?-cyclase from Citrus and its relation to lycopene accumulation  

UK PubMed Central (United Kingdom)

Carotenoids are the main pigments responsible of the colouration of Citrus fruits. The b2;-cyclization of lycopene, catalysed by the lycopene b2;-cyclases (b2;-LCY),...Full Text Available

2009-04-01

33

Mice With a Deletion in the Gene for CCAAT/Enhancer-Binding Protein ? are Protected Against Diet-Induced Obesity  

UK PubMed Central (United Kingdom)

The CCAAT/enhancer-binding protein b2; (C/EBPb2;) is required for adipocyte differentiation and maturation. We have studied the role of the transcription factor, C/EBPb2;,...Full Text Available

2007-01-01

34

Degradation of ?-Hexachlorocyclohexane by Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26  

UK PubMed Central (United Kingdom)

b2;-Hexachlorocyclohexane (b2;-HCH) is the most recalcitrant among the α-, b2;-, γ-, and δ-isomers of HCH and causes serious environmental pollution problems....Full Text Available

2005-04-01

35

Crystal Structure of the Mycobacterium fortuitum Class A ?-Lactamase: Structural Basis for Broad Substrate Specificity  

UK PubMed Central (United Kingdom)

b2;-Lactamases are the main cause of bacterial resistance to penicillins and cephalosporins. Class A b2;-lactamases, the largest group of b2;-lactamases, have been found in many bacterial...Full Text Available

2006-07-01

36

Contribution of Gene Amplification to Evolution of Increased Antibiotic Resistance in Salmonella typhimurium  

UK PubMed Central (United Kingdom)

The use of b2;-lactam antibiotics has led to the evolution and global spread of a variety of resistance mechanisms, including b2;-lactamases, a group of enzymes that degrade the b2;-lactam...Full Text Available

2009-08-01

39

Id theft module  

Science.gov (United States)

Web Security and Online Identity Theft

2009-02-03

41

Wideband Modulation and Tuning of Semiconductor Lasers ...  

Science.gov (United States)

... Tunable semiconductor lasers are essential components for links employing optical frequency modulation (OFM) for enhanced dynamic range or ...

1996-07-01

42

Zonal differences in DNA synthesis activity and cytochrome P450 gene expression in livers of male F344 rats treated with five nongenotoxic carcinogens  

Energy Technology Data Exchange (ETDEWEB)

Both increased cell proliferation and {open_quotes}altered{close_quotes}CYP gene expression are prominent phenomena associated with liver tumor promotion by nongenotoxic carcinogen treatment. BRDU-labeled parenchymal nuclei were observed primarily in the periportal area of groups of rats, independent of nongenotoxic carcinogen treatment. Treatment with each of the 5 nongenotoxic carcinogens resulted in profound alterations in CPY gene expression at both the transcriptional and translational levels. Expression of CYP1A1, 1A1/2, 3A1, 2B1/2, and 4A immunoproteins demonstrated nongenotoxic carcinogen-specific patterns in both magnitude and zonal distribution. In agreement with the CYP immunoprotein data, treatment with each of the five nongenotoxic carcinogens resulted in a unique composition of mRNAs of CYP2B1, 2B2, 2C6, 2C11, 3A1, 3A2, and 4A1, which were variably increased or decreased relative to the untreated control livers, depending on the ...

1995-12-31

43

Cell fate regulation by coupling mechanical cycles to biochemical signaling pathways  

British Library Electronic Table of Contents (United Kingdom)

Many aspects of cellular motility and mechanics are cyclic in nature such as the extension and retraction of lamellipodia or filopodia. Inherent to the cycles of extension and retraction that test the environment is the production of mechano-chemical signals that can alter long-term cell behavior, transcription patterns, and cell fate. We are just starting to define such cycles in several aspects of cell motility, including periodic contractions, integrin cycles of binding and release as well as the normal oscillations in motile activity. Cycles of local cell contraction and release are directly coupled to cycles of stressing and releasing extracellular contacts (matrix or cells) as well as cytoplasmic mechanotransducers. Stretching can alter external physical properties or sites exposed b...

2009-01-01

44

Transport and superconducting properties of RNi_2B_2C (R=Y, Lu) single crystals  

International Nuclear Information System (INIS)

The in-plane resistivity, in-plane absolute thermopower, and upper critical field measurements are reported for single-crystal samples of YNi_2B_2C and LuNi_2B_2C superconductors. The in-plane resistivity shows metallic behavior and varies approximately linearly with temperature near room temperature (RT) but shows nearly quadratic behavior in temperature at low temperatures. The YNi_2B_2C and LuNi_2B_2C single-crystal samples exhibit large transverse magnetoresistance (#approx#6 8% at 45 kOe) in the ab plane. The absolute thermopower S(T) is negative from RT to the superconducting transition temperature T_c. Its magnitude at RT is a few times of the value for a typical good metal. S(T) is approximately linear in temperature between #approx#150 K and RT. Extrapolation to T=0 gives large intercepts (few #mu#V/K) for both ...

46

Comparing Radiation Treatments Using Intensity-Modulated Beams, Multiple Arcs and Single Arc  

UK PubMed Central (United Kingdom)

PurposeA dosimetric comparison between multiple static-field intensity-modulated radiation therapy (IMRT), multi-arc intensity-modulated arc therapy (IMAT) and single-arc...Full Text Available

2010-04-01

47

Circuit design of PMT readout module for detector prototype of Daya Bay reactor neutrino experiment  

International Nuclear Information System (INIS)

This paper describes the design of PMT readout module for detector prototype of Daya Bay Reactor Neutrino Experiment. According to the design requirements of the readout module, the basic structure of the readout module is discussed. This paper also discusses how to realize the charge measurement and time measurement and data processing using a high performance FPGA. The DAQ system including three readout modules and one trigger module are well commissioned and doing data taking now. (authors)

2006-10-21

48

Computer Controlled Telerobot Wrist Module  

Science.gov (United States)

Disclosed in this proposal are plans to construct a patent pending wrist module with computer control, configurable to form high-dexerity telerobotic arms ...

49

A conceptual design for the module design and disc support structure for the ATLAS forward SCT tracker  

CERN Document Server

A conceptual design for the module design and disc support structure for the ATLAS forward SCT tracker

1996-01-01

50

Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidines as EGFR and ErbB-2 inhibitors  

British Library Electronic Table of Contents (United Kingdom)

A novel class of pyrrolidinyl-acetyleneic thieno[3,2-d]pyrimidines has been identified which potently inhibit the EGFR and ErbB-2 receptor tyrosine kinases. Synthetic modifications of the pyrrolidine carbamate moiety result in a range of effects on enzyme and cellular potency. In addition, the impact of the absolute stereochemical configuration on cellular potency and oral mouse pharmacokinetics is described.

2009-01-01

51

On the Origins of the Weak Folding Cooperativity of a Designed ??? Ultrafast Protein FSD-1  

UK PubMed Central (United Kingdom)

FSD-1, a designed small ultrafast folder with a b2;b2;α fold, has been actively studied in the last few years as a model system for studying protein folding mechanisms and for testing...Full Text Available

2010-11-01

52

Enhanced ?2-adrenergic receptor (?2AR) signaling by adeno-associated viral (AAV)-mediated gene transfer  

UK PubMed Central (United Kingdom)

Backgroundb2;2-Adrenergic receptors (b2;2AR) play important regulatory roles in a variety of cells and organ systems and are important therapeutic...Full Text Available

53

Dramatic Effects of 2-Bromo-5,6-Dichloro-1-?-d-Ribofuranosyl Benzimidazole Riboside on the Genome Structure, Packaging, and Egress of Guinea Pig Cytomegalovirus  

UK PubMed Central (United Kingdom)

The halogenated benzimidazoles BDCRB (2-bromo-5,6-dichloro-1-b2;-d-riborfuranosyl benzimidazole riboside) and TCRB (2,5,6-trichloro-1-b2;-d-riborfuranosyl benzimidazole...Full Text Available

2004-02-01

54

Design, synthesis, and testing of difluoroboron derivatized curcumins as near infrared probes for in vivo detection of amyloid-? deposits  

UK PubMed Central (United Kingdom)

Amyloid-b2; (Ab2;) deposits have been identified as key players in the progression of Alzheimer’s disease (AD). Recent evidence indicates that the deposits probably precede...Full Text Available

2009-10-28

55

Clavulanic Acid, a Novel Inhibitor of ?-Lactamases  

UK PubMed Central (United Kingdom)

Clavulanic acid, Z-(2R,5R)-3-(b2;-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0] heptane-2-carboxylic acid, has been shown to be an effective inhibitor of the b2;-lactamases of the...Full Text Available

1978-11-01

56

A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice  

UK PubMed Central (United Kingdom)

Amyloid plaques are a characteristic feature in Alzheimer’s disease (AD). A novel non-toxic contrast agent is presented, Gd-DTPA-K6Ab2;1–30, which is homologous to Ab2;,...Full Text Available

2008-06-01

62

Electrostatic simulation of the modulated electron beam interaction with inhomogeneous plasma  

International Nuclear Information System (INIS)

... Union (INTAS), Brussels (Belgium) Science and Technology Center in Unkraine,

2006-09-11

65

Resonantlike phenomenon in short-pulse free-electron-laser oscillators with modulated desynchronism  

International Nuclear Information System (INIS)

Recently a new method of controlling the pulse length of a short-pulse free-electron laser (FEL) has been developed. By modulating the synchronism between the optical and electron pulses in the FEL cavity, it was found that the output power and the micropulse length of the FEL beam oscillates at the modulation frequency. In this paper, we study theoretically the behavior of the micropulse length, both in the high loss (steady state) regime and the low loss (limit cycle) regime, when a modulated desynchronism is applied. In order to do this, we analyze the dynamics of a short-pulse FEL oscillator. The modulation frequency value plays an important role in the dynamics. We find that there is a resonantlike phenomenon between the externally applied desynchronism modulation and the limit cycle oscillation without modulation of a free-electron laser.

2002-01-01

66

Design of multifunction anti-terrorism robotic system based on police dog  

Science.gov (United States)

Aimed at some typical constraints of police dogs and robots used in the areas of reconnaissance and counterterrorism currently, the multifunction anti-terrorism robotic system based on police dog has been introduced. The system is made up of two parts: portable commanding device and police dog robotic system. The portable commanding device consists of power supply module, microprocessor module, LCD display module, wireless data receiving and dispatching module and commanding module, which implements the remote control to the police dogs and takes real time monitor to the video and images. The police dog robotic system consists of microprocessor module, micro video module, wireless data transmission module, power supply module and offence weapon module, which real time collects ...

2007-11-01

67

Luminescent properties of Eu3+-activated Sr3B2SiO8: A red-emitting phosphor for white light-emitting diodes  

International Nuclear Information System (INIS)

Single-phased Sr3B2SiO8:Eu3+ phosphor was prepared by a solid-state method at 1020 oC. The luminescence spectra showed that Sr3B2SiO8:Eu3+ phosphor can be effectively excited by near ultraviolet light (393 nm) and blue light (464 nm). When excited at 393 or 464 nm Sr3B2SiO8:Eu3+ exhibited the main emission peaks at 611 and 620 nm, which resulted from the supersensitive 5D0#->#7F2 transition of Eu3+. The luminescence intensity of Sr3B2SiO8:Eu3+ at 611 and 620 nm reached the maximum when the doping content of Eu3+ was 4.5 mol%. Its chromaticity coordinates (0.646, 0.354) were very close to the NTSC standard values (0.67, 0.33). Thus, Sr3B2SiO8:Eu3+ is considered to be an efficient red-emitting phosphor for long-UV InGaN-based light-emitting diodes. - Highlights: ? ...

2011-07-01

68

Lithium isotope separation by cryptand (2 sub(B), 2, 1) polymer  

Energy Technology Data Exchange (ETDEWEB)

Single stage separation factors ..cap alpha.. have been determined for /sup 6/Li and /sup 7/Li between lithium ions in methanol and complexed ions with a cryptand (2 sub(B), 2, 1) polymer. The /sup 6/Li was concentrated in the cryptand. The separation factors were compared with the values of other chemical exchange systems. The maximum enrichment factor obtained was epsilon = 0.047 +- 0.002. The figure is one of the greatest in the chemical exchange reactions without valence change and almost 10 times larger than the values of ion exchangers. The variation in ..cap alpha.. depending on the chemical species was small in the non-aqueous system. High enrichment of lithium isotopes was expected to be achievable by means of the chromatographic application of the cryptand (2 sub(B), 2, 1).

1984-02-01

69

Performance, Operation and Maintenance Management System ``POMMS``: EPRI`s monitoring system for gas turbines and combined cycle plants  

Energy Technology Data Exchange (ETDEWEB)

This paper describes EPRI`s computer based Performance, Operation and Maintenance Management System (``POMMS``) consisting of four (4) modules (``Modules``). These Modules are used to monitor, evaluate and analyze the cost effective operation of simple cycle and combined cycle gas turbine power plants. Inputs to POMMS relating to plant performance, availability and maintenance are monitored, stored in a data acquisition system and analyzed to determine their impact on performance and cost parameters. POMMS was developed by EPRI, Project Manager Fluor Daniel Power Generation Company and by the subcontractors who, together, engineered the individual POMMS Modules while working on EPRI`s Durability Surveillance of Advanced Gas Turbines Project (``Project``). The following modules are described in this paper and may be applied together or individually: Rotating Blade Temperature ...

1994-12-31

70

Integration of turbo-generator modules in digital transient network analyzer  

Science.gov (United States)

The behavior of a small power system consisting of two interconnected generators is simulated in real-time by a prototype Digital Transient Network Analyzer (TNA). The prototype Digital TNA consists of two Computational Modules and one I/O Module. The Modules communicate with each other through ribbon cables. Each Computational Module simulates one Turbo-Generator, its Transformer, its Governor, Exciter, and Power System Stabilizer Systems. The numerical integration is shared by two TMS320C30 DSPs at a step-size of 100 microseconds in real-time. The I/O module post-processes the state variables and presents selected information for analog display. The paper presents oscillograms from a test program which includes symmetry checks and behavioral checks against well known waveforms of hunting oscillations, synchronization out-of-phase torques, and subsynchronous resonance phenomena. ...

1994-05-01

71

Proteomic analysis of the shistosome tegument and its surface membranes  

Scientific Electronic Library Online (English)

Abstract in english The tegument surface of the adult schistosome, bounded by a normal plasma membrane overlain by a secreted membranocalyx, holds the key to understanding how schistosomes evade host immune responses. Recent advances in mass spectrometry (MS), and the sequencing of the Schistosoma mansoni transcriptome/genome, have facilitated schistosome proteomics. We detached the tegument from the worm body and enriched its surface membranes by differential extraction, before subjecting t (more) he preparation to liquid chromatography-based proteomics to identify its constituents. The most exposed proteins on live worms were labelled with impearmeant biotinylation reagents, and we also developed methods to isolate the membranocalyx for analysis. We identified transporters for sugars, amino acids, inorganic ions and water, which confirm the importance of the tegument plasma membrane in nutrient acquisition and solute balance. Enzymes, including phosphohydrolases, esterases and ...

2006-10-01

72

Technical evaluation of Solar Cells, Inc., CdTe module and array at NREL  

Energy Technology Data Exchange (ETDEWEB)

The Engineering and Technology Validation Team at the National Renewable Energy Laboratory (NREL) conducts in-situ technical evaluations of polycrystalline thin-film photovoltaic (PV) modules and arrays. This paper focuses on the technical evaluation of Solar Cells, Inc., (SCI) cadmium telluride (CdTe) module and array performance by attempting to correlate individual module and array performance. This is done by examining the performance and stability of the modules and array over a period of more than one year. Temperature coefficients for module and array parameters (P{sub max}, V{sub oc}, V{sub max}, I{sub sc}, I{sub max}) are also calculated.

1996-05-01

73

Solar energy modulator  

Energy Technology Data Exchange (ETDEWEB)

A module is described with a receiver having a solar energy acceptance opening and supported by a mounting ring along the optic axis of a parabolic mirror in coaxial alignment for receiving solar energy from the mirror, and a solar flux modulator plate for varying the quantity of solar energy flux received by the acceptance opening of the module. The modulator plate is characterized by an annular, plate-like body, the internal diameter of which is equal to or slightly greater than the diameter of the solar energy acceptance opening of the receiver. Slave cylinders are connected to the modulator plate for supporting the plate for axial displacement along the axis of the mirror thereby shading the opening with respect to solar energy flux reflected from the surface of the mirror to the solar energy acceptance opening.

1981-07-01

74

Navy Occupational Health Information Management System (NOHIMS). Hazardous Materials Control Module. Users' manual  

Energy Technology Data Exchange (ETDEWEB)

The Hazardous Materials Control Module (HMC) is one module of four for the Industrial Health component. The HMC module was designed to inform employees of health and safety hazards in the workplace and to track the movement of hazardous materials through the facility. The module performs these functions by maintaining health and safety data on hazardous materials used in the facility, and by tracking who requests information about any hazardous materials. The HMC module gets its information from two sources. The first one is the Hazardous Materials Information System (HMIS), this is a national system that is used by the Department of Defense. It is loaded on to the system via tapes that contain all safety, health and transportation information about a particular product. The second is Material Safety Data Sheets (MSDS) that are procured by a particular site. This information is ...

1987-01-16

75

MINERGIE modules: heat pump - heat pump/solar - wood - wood/solar; Minergie-Module Waermepumpe - Waermepumpe/Solar - Holz - Holz/Solar  

Energy Technology Data Exchange (ETDEWEB)

This research report for the Swiss Federal Office of Energy (SFOE) presents the results of a project that examined the feasibility of setting up 'MINERGIE' low-energy-consumption module standards for the production of heat in small residential buildings. The aims of the standards and the basic idea behind the MINERGIE-modules are discussed. The concepts of the modules for heat pumps and wood-fired heating systems and their combination with solar installations are examined, as are their areas of application. The requirements placed on the modules are listed. System concepts, including simple schematics for typical installations, are presented for wood-log, wood-chippings and pellets-fired systems as well as for ground-loop and air-water heat pump systems as well as their solar-aided counterparts. The results of cost-benefit analyses are presented and questions regarding system guarantee ...

2005-07-01

76

Disruptive core relocation analysis of PHEBUS/FPT0 test with SAMPSON code  

International Nuclear Information System (INIS)

SAMPSON is an integration of twelve analysis modules under the final development phase (phase-2) and will be capable of simulating hypothesized severe accidents in a nuclear power plant. One of these modules, the Molten Core Relocation Analysis (MCRA) module, simulates the relocation behavior of a molten core during a severe accident. MCRA models severe accident phenomena by using mechanistic formulations for multi-phase, multi-component, and multi-velocity field. As one of the verification studies of SAMPSON in Phase-1, the in-core phenomena of PHEBUS/FPT0 was analyzed with three modules, MCRA, fuel rod heat up analysis (FRHA) module, and the analysis control module (ACM) of SAMPSON. (author)

2000-10-01

77

Stabilization of ?-catenin induces pancreas tumor formation  

UK PubMed Central (United Kingdom)

Background & Aimsb2;-catenin signaling within the canonical Wnt pathway is essential for pancreas development. However, the pathway is normally down-regulated...Full Text Available

2008-10-01

78

Selecting Folded Proteins from a Library of Secondary Structural Elements  

UK PubMed Central (United Kingdom)

A protein evolution strategy is described by which double-stranded DNA fragments encoding defined E. coli protein secondary structural elements (α-helices, b2;-strands...Full Text Available

2008-01-09

79

Role of Estrogen Receptor-? in the Regulation of Claudin-6 Expression in Breast Cancer Cells  

UK PubMed Central (United Kingdom)

PurposeIn our previous studies we showed that upregulating claudin-6 (CLDN6) expression may contribute to preventing breast cancer, and that 17b2;-estradiol induces a concentration-...Full Text Available

2011-03-01

80

Renal functions in pediatric patients with beta-thalassemia major: relation to chelation therapy: original prospective study  

UK PubMed Central (United Kingdom)

BackgroundIn b2;-thalassemia, profound anemia and severe hemosiderosis cause functional and physiological abnormalities in various organ systems. In recent years, there have...Full Text Available

81

Relation between regional and global systolic function in patients with ischemic cardiomyopathy after ?-Blocker therapy or revascularization  

UK PubMed Central (United Kingdom)

BackgroundTo assess the relationship between improved regional and global myocardial function in patients with ischemic cardiomyopathy in response to b2;-blocker therapy or...Full Text Available

82

Nuclear ? catenin as a potential prognostic and diagnostic marker in patients with colorectal cancer from Hong Kong  

UK PubMed Central (United Kingdom)

Aims: To study the expression of nuclear b2; catenin in patients with colorectal cancer, colorectal adenoma, and colorectal polyps to elucidate its role in carcinogenesis, and its...Full Text Available

2003-12-01

83

Noncooperativity of the ?? Dimer in the Reaction of Hemoglobin with Oxygen  

UK PubMed Central (United Kingdom)

The theory that the αb2; dimer is the functional unit of cooperativity in hemoglobin has been tested by determination of the oxygen equilibrium curve of stable deoxy dimers, obtained by...Full Text Available

1972-01-01

84

Neutron shielding and constructional characteristics of a new type concrete and from borated clinker  

International Nuclear Information System (INIS)

A boron containing cement, which can be used as nuclear shielding material, is produced at pilot plant scale applying two different methods. In the first method, the raw mixture of a normal portland cement is mixed with pre-calcined colemanite, a calcium borate mineral, and clinkerized in a rotary kiln (borated-clinker). In the second method, the colemanite is mixed with an admixture, which contains mainly limestone and marl, and burnt in the rotary kiln to obtain a borated-lime composite. The borated-lime composite is then added to the normal portland cement clinker up to 2% B_2O_3 content for shielding purpose. The results have shown that the borated-clinker contained untolerable amount of free lime resulting in a decrease in compressive strength. The addition of the borated-lime composite to the normal portland cement clinker up to 1% B_2O_3 content did not alter the setting time and the volume ...

1994-11-07

85

Molecular and Kinetic Comparison of the Novel Extended-Spectrum ?-Lactamases CTX-M-25 and CTX-M-26  

UK PubMed Central (United Kingdom)

CTX-M-25 is a novel extended-spectrum b2;-lactamase isolated from a single Canadian Escherichia coli isolate. Susceptibility testing demonstrated that this enzyme confers resistance...Full Text Available

2004-12-01

86

Molecular Epidemiology of Escherichia coli Producing Extended-Spectrum ?-Lactamases Isolated in Rome, Italy?  

UK PubMed Central (United Kingdom)

Escherichia coli strains producing extended-spectrum b2;-lactamases (ESBLs) are a major problem in many different hospitals worldwide, causing outbreaks as well as sporadic infections....Full Text Available

2008-01-01

87

Loss of ?-III spectrin leads to Purkinje cell dysfunction recapitulating the behaviour and neuropathology of SCA5 in humans  

UK PubMed Central (United Kingdom)

Mutations in SPTBN2, the gene encoding b2;-III spectrin, cause spinocerebellar ataxia type 5 in humans (SCA5), a neurodegenerative disorder resulting in loss of motor...Full Text Available

2010-04-07

88

Insulin and Glucagon Regulate Pancreatic ?-Cell Proliferation  

UK PubMed Central (United Kingdom)

Type 2 diabetes mellitus (T2DM) results from insulin resistance and b2;-cell dysfunction, in the setting of hyperglucagonemia. Glucagon is a 29 amino acid peptide hormone, which is secreted from...Full Text Available

89

Influence of microenvironment on engraftment of transplanted ?-cells  

UK PubMed Central (United Kingdom)

Pancreatic islet transplantation into the liver provides a possibility to treat selected patients with brittle type 1 diabetes mellitus. However, massive early b2;-cell death increases the number...Full Text Available

2011-02-01

90

Infected foot ulcers in male and female diabetic patients: a clinico-bioinformative study  

UK PubMed Central (United Kingdom)

BackgroundThe study aimed at (i) characterizing the mode of transmission of blaCTX-M and blaTEM-1 among extended-spectrum-b2;-lactamase...Full Text Available

91

Identifying and validating biomarkers for Alzheimer's disease  

UK PubMed Central (United Kingdom)

The identification and validation of biomarkers for diagnosing Alzheimer's disease (AD) and other forms of dementia are increasingly important. To date, ELISA measurement of b2;-amyloid(1–42),...Full Text Available

2011-01-01

92

Identification of CTX-M-Type Extended-Spectrum-?-Lactamase Genes Using Real-Time PCR and Pyrosequencing?  

UK PubMed Central (United Kingdom)

CTX-M extended-spectrum b2;-lactamases (ESBLs) are increasingly prevalent worldwide among Escherichia coli bacteria, mostly in community-acquired urinary tract infections. Finding...Full Text Available

2007-01-01

93

Identification of CTX-M-14 Extended-Spectrum ?-Lactamase in Clinical Isolates of Shigella sonnei, Escherichia coli, and Klebsiella pneumoniae in Korea  

UK PubMed Central (United Kingdom)

CTX-M-14 b2;-lactamase was identified in a stool isolate of Shigella sonnei and in blood isolates of Escherichia coli (one isolate) and Klebsiella pneumoniae...Full Text Available

2001-10-01

94

Genetic Variation at the Mitochondrial DNA 9-bp Repeat Locus in the Sakha of Siberia  

Science.gov (United States)

... 16223, 16292, and 16295, which classify them as haplogroup W (Richards et al. 2000). The sample that was ... belonged to haplogroup B, 2 individuals belonged to haplogroup W, and 1 individual belonged to ...

95

Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages  

UK PubMed Central (United Kingdom)

Dectin-1, the major b2;-glucan receptor in leukocytes, triggers an effective immune response upon fungal recognition. Here we use sortase-mediated transpeptidation, a technique that allows placement...Full Text Available

2011-08-23

96

Flexible responses to visual and olfactory stimuli by foraging Manduca sexta: larval nutrition affects adult behaviour  

UK PubMed Central (United Kingdom)

Here, we show that the consequences of deficient micronutrient (b2;-carotene) intake during larval stages of Manduca sexta are carried across metamorphosis, affecting adult behaviour....Full Text Available

2009-08-07

97

Emergence of Enterobacteriaceae Isolates Producing CTX-M Extended-Spectrum ?-Lactamase in Austria  

UK PubMed Central (United Kingdom)

Among 149 extended-spectrum b2;-lactamase (ESBL)-producing Enterobacteriaceae isolates collected from patients in southeast Austria from 1998 to 2004, 38 Escherichia coli...Full Text Available

2006-02-01

98

Effect of iron and boron carbide on the densification and mechanical properties of titanium diboride ceramics  

International Nuclear Information System (INIS)

The effects of Fe and B_4C on the sintering behavior and mechanical properties of TiB_2 ceramics have been studied. Sintering was performed in an Ar atmosphere at 2000 degrees C using attrition-milled TiB_2 powder. When a small amount of Fe (0.5 wt%) was added, abnormal grain growth occurred and the sintered density was low. In the case of B_4C added along with 0.5 wt% Fe, however, abnormal grain growth was remarkably suppressed, and the sintered density was increased up to 95% of theoretical. But with excess Fe addition (5 wt%), B_4C grains did not act as a grain growth inhibitor, and B_4C grains were frequently trapped in large TiB_2 grains. The best mechanical properties were obtained for the TiB_2-10 wt% B_4C-0.5 wt% Fe ceramics, which exhibited a three-point bending strength of 400 MPa and a fracture toughness of ...

99

Effect of Li-Al co-doping on the energy gaps of MgB2  

International Nuclear Information System (INIS)

We studied the effects of co-doping with Li and Al on the energy gaps of MgB2 by performing point-contact Andreev-reflection spectroscopy (PCAR) in polycrystalline Mg1-x(Al?Li1-?)xB2 samples with x?0.4. Even though the lattice parameters and the critical temperature of the compound simply scale with the effective Al content ?x, irrespective of the Li concentration, the energy gaps do not. In particular, for a given effective Al content, the comparison with Mg1-y(Al)yB2 with y = ?x shows that the ? bandgap is practically the same while the ? bandgap is higher. A clear gap merging is observed in the most doped sample (x = 0.4) when Tc<20 K. The results are discussed within the two-band Eliashberg theory and compared to the outcomes of first-principles calculations of the effects of Li and Al co-doping on the electronic structure of magnesium diboride.

2009-02-01

100

EPR and FT-IR spectroscopic studies of Bi2O3-B2O3-CuO glasses  

International Nuclear Information System (INIS)

EPR and FT-IR absorption measurements have been performed for xCuO.(100-x)[2Bi2O3.B2O3] glass system, with 0?x?50 mol%. The mode in which the addition of the copper ions influences the structure of 2Bi2O3.B2O3 glass matrix was analyzed. The EPR absorption spectra revealed the presence in the glass structure of Cu2+ ions in axially distorted octahedral environments. EPR data pointed out the simultaneous presence of Cu2+ and Cu+ ionic species in the glasses with x?5 mol%. For x>10 mol%, the Cu2+ ions participate in the superexchange magnetic interactions, which increase with CuO content. The FT-IR spectra showed the presence of some bands that are assigned to vibrations of Bi-O bonds from BiO3 pyramidal and BiO6 octahedral units and B-O bonds from BO3 and BO4 units. The data obtained by these measurements reveal the structural changes in the 2Bi2O3.B2O3 glass ...

2008-10-01

101

Dissemination of CTX-M-Type Extended-Spectrum ?-Lactamase Genes to Unusual Hosts  

UK PubMed Central (United Kingdom)

A Citrobacter amalonaticus and a Morganella morganii producing the CTX-M-1 extended-spectrum b2;-lactamase (ESBL) were isolated from an area where this enzyme...Full Text Available

2005-08-01

102

Characterization of a Chromosomally Encoded Extended-Spectrum Class A ?-Lactamase from Kluyvera cryocrescens  

UK PubMed Central (United Kingdom)

A chromosomally located b2;-lactamase gene, cloned and expressed in Escherichia coli from a reference strain of the enterobacterial species Kluyvera cryocrescens,...Full Text Available

2001-12-01

103

Characterization of Terfestatin A, a New Specific Inhibitor for Auxin Signaling1[w  

UK PubMed Central (United Kingdom)

Terfestatin A (TrfA), terphenyl-b2;-glucoside, was isolated from Streptomyces sp. F40 in a forward screen for compounds that inhibit the expression of auxin-inducible...Full Text Available

2005-10-01

104

Characterization of Multidrug Resistant ESBL-Producing Escherichia coli Isolates from Hospitals in Malaysia  

UK PubMed Central (United Kingdom)

The emergence of Escherichia coli that produce extended spectrum b2;-lactamases (ESBLs) and are multidrug resistant (MDR) poses antibiotic management problems....Full Text Available

2009-01-01

105

CTX-M-Type Extended-Spectrum ?-Lactamases in Italy: Molecular Epidemiology of an Emerging Countrywide Problem  

UK PubMed Central (United Kingdom)

A nationwide survey of extended-spectrum b2;-lactamase (ESBL) production among Enterobacteriaceae, carried out in 2003, showed that CTX-M-type enzymes have achieved a sizeable...Full Text Available

2006-08-01

106

CTX-M ?-Lactamases in Escherichia coli from Community-acquired Urinary Tract Infections, Cambodia  

UK PubMed Central (United Kingdom)

Despite the recent global spread of CTX-M b2;-lactamases in Escherichia coli isolates from community-acquired urinary tract infections (CA-UTIs), their dissemination has been...Full Text Available

2009-05-01

107

Beyond AICA Riboside: In Search of New Specific AMP-activated Protein Kinase Activators  

UK PubMed Central (United Kingdom)

Summary5-Aminoimidazole-4-carboxamide-1-b2;-d-ribofuranoside (AICA riboside) has been extensively used in vitro and in vivo to...Full Text Available

2009-01-01

108

Behavioral Defects in Chaperone-Deficient Alzheimer's Disease Model Mice  

UK PubMed Central (United Kingdom)

Molecular chaperones protect cells from the deleterious effects of protein misfolding and aggregation. Neurotoxicity of amyloid-beta (Ab2;) aggregates and their deposition in senile plaques are...Full Text Available

109

Antagonistic crosstalk between APC and HIF-1?  

UK PubMed Central (United Kingdom)

Most colorectal cancers have mutations in the tumor suppressor APC. The best-understood function of APC is its participation in a protein complex that regulates the availability of b2;-catenin....Full Text Available

2011-05-15

110

Animal Models in Carotenoids Research and Lung Cancer Prevention1  

UK PubMed Central (United Kingdom)

Numerous epidemiological studies have consistently demonstrated that individuals who eat more fruits and vegetables (which are rich in carotenoids) and who have higher serum b2;-carotene levels...Full Text Available

111

Analysis of the Pharmacokinetic Interaction between Cephalexin and Quinapril by a Nonlinear Mixed-Effect Model  

UK PubMed Central (United Kingdom)

Oligopeptidic drugs such as b2;-lactams and angiotensin-converting enzyme inhibitors share the same carriers in humans and animals, which results in possible pharmacokinetic interactions. To model...Full Text Available

1998-06-01

112

A Dominant Role for the Immunoproteasome in CD8+ T Cell Responses to Murine Cytomegalovirus  

UK PubMed Central (United Kingdom)

Murine cytomegalovirus (MCMV) is an important animal model of human cytomegalovirus (HCMV), a b2;-Herpesvirus that infects the majority of the world's population and causes disease in neonates...Full Text Available

113

Theoretical study of the phonon properties of SrS  

International Nuclear Information System (INIS)

Using an ab initio pseudopotential method within a generalized gradient approximation of the density functional theory, the structural, electronic, and phonon properties of SrS in the B1 (NaCl) and B2 (CsCl) structures have been studied. The calculated lattice constants, static bulk modulus, and first-order pressure derivative of the bulk modulus are reported for both the B1 and B2 structures and compared with previous experimental and theoretical calculations. Electronic band structures and densities of states have been derived for SrS. Subsequently, a linear-response approach to the density functional theory is used to derive the phonon frequencies and densities of states.

2009-05-25

114

Vitamins B2 and B6 and genetic polymorphisms related to one-carbon metabolism as risk factors for gastric adenocarcinoma in the European prospective investigation into cancer and nutrition  

DEFF Research Database (Denmark)

B vitamins and polymorphisms in genes coding for enzymes involved in one-carbon metabolism may affect DNA synthesis and methylation and thereby be implicated in carcinogenesis. Previous data on vitamins B2 and B6 and genetic polymorphisms other than those involving MTHFR as risk factors for gastric cancer (GC) are sparse and inconsistent. In this case-control study nested within the European Prospective Investigation into Cancer and Nutrition cohort, cases (n = 235) and controls (n = 601) were matched for study center, age, sex, and time of blood sampling. B2 and B6 species were measured in plasma, and the sum of riboflavin and flavin mononucleotide was used as the main exposure variable for vitamin B2 status, whereas the sum of pyridoxal 5'-phosphate, pyridoxal, and 4-pyridoxic acid was used to define vitamin B6 status. In addition, we determined eight ...

2010-01-01

115

Thymol, a constituent of thyme essential oil, is a positive allosteric modulator of human GABAA receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster  

UK PubMed Central (United Kingdom)

The GABA-modulating and GABA-mimetic activities of the monoterpenoid thymol were explored on human GABAA and Drosophila melanogaster...Full Text Available

2003-12-01

116

Selective estrogen receptor modulator (SERM) for the treatment of osteoporosis in postmenopausal women: focus on lasofoxifene  

UK PubMed Central (United Kingdom)

Selective estrogen receptor modulators (SERMs) represent a class with a growing number of compounds that act as either estrogen receptor agonists or antagonists in a tissue-specific manner. This article...Full Text Available

2010-01-01

117

Rate of allosteric change in hemoglobin measured by modulated excitation using fluorescence detection.  

UK PubMed Central (United Kingdom)

We have measured the forward and reverse rates of the allosteric transition of hemoglobin A with three CO molecules bound by using modulated excitation coupled with fluorescence quenching of the DPG...Full Text Available

1989-10-01

118

NAME=\\  

Wastenet

...this pathway study the following two focus modules (in addition to the six core modules) and carry out a research investigation within this theme: Agricultural Production Systems Considers the type of farming systems that have evolved globally in relation to the prevailing agro-climatic zones, the influences of economic factors ...

119

Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants  

UK PubMed Central (United Kingdom)

Many lifespan-modulating genes are involved in either generation of oxidative substrates and end-products, or their detoxification and removal. Among such metabolites, only lipoperoxides have the ability...Full Text Available

120

Modulation of Expression of the ToxR Regulon in Vibrio cholerae by a Member of the Two-Component Family of Response Regulators  

UK PubMed Central (United Kingdom)

The ToxRS system in Vibrio cholerae plays a central role in the modulation of virulence gene expression in response to environmental stimuli. An integration of multiple signalling inputs...Full Text Available

1998-12-01

121

Intensity modulated radiotherapy: advantages, limitations and future developments  

UK PubMed Central (United Kingdom)

Intensity modulated radiotherapy (IMRT) is widely used in clinical applications in developed countries, for the treatment of malignant and non-malignant diseases. This technique uses multiple radiation...Full Text Available

122

Construction of a Continuous Wave Frequency Modulation ...  

Science.gov (United States)

... Steady State 16.0-28.0 5.05 to 5.36 0 Key switch turned on. ... version may have been the better choice since the acousto-optic modulator also ...

1997-03-01

123

Comparison of coplanar and noncoplanar intensity-modulated radiation therapy and helical tomotherapy for hepatocellular carcinoma  

UK PubMed Central (United Kingdom)

BackgroundTo compare the differences in dose-volume data among coplanar intensity modulated radiotherapy (IMRT), noncoplanar IMRT, and helical tomotherapy (HT) among patients with...Full Text Available

124

A Picture Archiving and Communication System Module for Radiology  

UK PubMed Central (United Kingdom)

This paper presents the design and implementation of a clinical picture archiving and communication system (PACS) module within the radiology department of a 700-bed teaching hospital. The system is...Full Text Available

1988-11-09

125

Transverse velocity modulated e-beam propagating through an undulator as a source of coherent spontaneous radiation  

International Nuclear Information System (INIS)

A new kind of e-beam bunching enabling the production of coherent spontaneous emission (CSE) is proposed and considered. It is shown that an e-beam in passing through an undulator will induce CSE along with incoherent spontaneous radiation on the same wavelength if the e-beam transverse velocity is modulated with a spatial period twice as long as the radiation wavelength. Such angular modulated beams can be regarded as alternatives to conventionally density modulated beams for CSE production. Requirements for e-beams are similar in both cases.

1999-06-01

126

Photovoltaic module energy rating procedure. Final subcontract report  

Energy Technology Data Exchange (ETDEWEB)

This document describes testing and computation procedures used to generate a photovoltaic Module Energy Rating (MER). The MER consists of 10 estimates of the amount of energy a single module of a particular type (make and model) will produce in one day. Module energy values are calculated for each of five different sets of weather conditions (defined by location and date) and two load types. Because reproduction of these exact testing conditions in the field or laboratory is not feasible, limited testing and modeling procedures and assumptions are specified.

1998-01-01

127

Femtosecond Photonics: Fundamental Phenomena and ...  

Science.gov (United States)

... concentrated on the construction of switches using fiber ... been chosen for a switch realized in ... of these techniques using acousto-optic modulators or ...

1992-02-10

128

Transverse velocity modulator and generator schemes based on non-collinear radiation and electron beams  

International Nuclear Information System (INIS)

New non-collinear schemes are suggested for transverse velocity modulation of electron beams and for the generation of coherent spontaneous radiation by these transversely modulated beams. It is shown that due to the non-collinearity some orders of magnitude enhancement can be achieved for the coherent spontaneous radiation (CSR) power at both the fundamental and harmonic frequencies.

2000-05-01

129

Quasifinite highest weight modules over the super W 1 + #infinity#algebra  

International Nuclear Information System (INIS)

We study quasifinite highest weight modules over the supersymmetric extension of the W_1_+_#infinity# algebra on the basis of the analysis by Kac and Radul. We find that the quasifiniteness of the modules is again characterized by polynomials, and obtain the differential equations for highest weights. The spectral flow, free field realization over the (B, C)-system, and the embedding into gl(#infinity#vertical stroke #infinity#) are also presented. (orig.).

1995-01-01

130

Modulation instability of linearly polarized laser pulse in relativistic plasma  

International Nuclear Information System (INIS)

Based on the nonlinear dispersion relation of electromagnetic wave in relativistic plasma, the nonlinear controlling equation for linearly polarized mode is obtained using Karpman's method. The modulation instability of intense laser pulse propagating through relativistic plasma is analyzed and the modulation instability growth rate as a function of perturbation wave number for laser beam propagating through relativistic plasma is given. (authors)

2008-10-01

131

MIZAR mz8310  

Science.gov (United States)

The mz8310 device support module provides support for the following record types: event, pulseCounter, pulseDelay, and pulseTrain. No driver support is needed. Up to 4 mz8310 modules are supported. Each 8310 module contains 10 channels, which are identified as signals O,...9. Each channel is individually configurable. Each mz83 10 has two Am9513 Timing Controller chips. Each Am9513 has 5 counters.

1992-07-09

132

Modeling of an Inductive Adder Kicker Pulser for a Proton Radiography System  

Energy Technology Data Exchange (ETDEWEB)

An all solid-state kicker pulser for a proton radiography system has been designed. Multiple solid-state modulators stacked in an inductive-adder configuration are utilized in this kicker pulser design. Each modulator is comprised of multiple metal-oxide-semiconductor field-effect transistors (MOSFETs) which quickly switch the energy storage capacitors across a magnetic induction core. Metglas is used as the core material to minimize loss. Voltage from each modulator is inductively added by a voltage summing stalk. A circuit model of a prototype inductive adder kicker pulser modulator has been developed to predict the performance of the pulser modulator. The modeling results are compared with experimental data.

2001-06-12

133

GABAB Receptors Modulate NMDA Receptor Calcium Signals in Dendritic Spines  

British Library Electronic Table of Contents (United Kingdom)

Summary Metabotropic GABAB receptors play a fundamental role in modulating the excitability of neurons and circuits throughout the brain. These receptors influence synaptic transmission by inhibiting presynaptic release or activating postsynaptic potassium channels. However, their ability to directly influence different types of postsynaptic glutamate receptors remains unresolved. Here we examine GABAB receptor modulation in layer 2/3 pyramidal neurons from the mouse prefrontal cortex. We use two-photon laser-scanning microscopy to study synaptic modulation at individual dendritic spines. Using two-photon optical quantal analysis, we first demonstrate robust presynaptic modulation of multivesicular release at single synapses. Using two-photon glutamate uncaging, we then reveal that GABAB r...

2010-01-01

134

Design and operating experience of a 40 MW, highly-stabilized power supply  

Energy Technology Data Exchange (ETDEWEB)

Four 10 MW, highly-stabilized power supply modules have been installed at the National High Magnetic Field Laboratory in Tallahassee, FL, to energize water-cooled, resistive, high-field research magnets. The power supply modules achieve a long term current stability if 10 ppM over a 12 h period with a short term ripple and noise variation of <10 ppM over a time period of one cycle. The power supply modules can operate independently, feeding four separate magnets, or two, three or four modules can operate in parallel. Each power supply module consists of a 12.5 kV vacuum circuit breaker, two three-winding, step-down transformers, a 24-pulse rectifier with interphase reactors, and a passive and an active filter. Two different transformer tap settings allow rated dc supply output voltages of 400 and 500 V. The rated current of a supply module is 17 kA and each ...

1995-07-01

135

Time-dependent infrared emission following photodissociation of nitromethane and chloropicrin.  

Science.gov (United States)

Nitromethane (CH(3)NO(2)) and its chlorinated analogue, chloropicrin (CCl(3)NO(2)), were photolyzed at 193, 248, and 266 nm, and the products were observed by time-dependent Fourier transform infrared emission spectroscopy. At 193 and 248 nm, the primary photodissociation pathway for nitromethane was cleavage of the C-N bond to produce CH(3) + NO(2)(A (2)B(2)). At 266 nm, weak emission was observed following photodissociation of nitromethane, but an infrared spectrum could not be obtained. The photodissociation of chloropicrin at 193 nm produced the analogous product channel CCl(3) + NO(2)(A (2)B(2)) in addition to several other product channels. At 248 and 266 nm, only CCl(3) + NO(2)(A (2)B(2)) was observed. The production of phosgene (CCl(2)O) from chloropicrin photodissociation was not observed in this study. PMID:16571044

2006-04-01

136

The pressure- and temperature dependence of the electrical resistivity of some amorphous Fe-B alloys  

International Nuclear Information System (INIS)

We report measurements of the electrical resistivity of the amorphous alloys Fe"4"0Ni"4"0P"1"4B"6 (Metglas 2826), Fe"3"2Ni"3"6Cr"1"4Pr"1"2B"6 (Metglas 2826A) Fe"8"0B"2"0 (Metgals 2605) and Fe"7"5B"2"5 as a function of pressure and temperature. The pressure is varied between 0 and 12 GPa, the temperature between 1.2 and 380 K. At low temperatures the pressure dependence yields additional information on the scattering mechanism. (orig.).

137

Revenue management: the impact on business-to-business relationships  

British Library Electronic Table of Contents (United Kingdom)

Purpose - This paper aims to explore the links between revenue management and business-to-business (B2B) relationships and explains how revenue management can both support and damage B2B relationships. Design/methodology/approach - A single case study method was employed to conduct qualitative research into a company and its key accounts. In-depth data were collected from three divergent sources (company revenue managers, company account managers and nine of the company's key accounts) through semi-structured interviews, observations and document studies. Findings - The research findings reveal that from the company's perspective, managers acknowledge that revenue management has positively influenced the process of identifying and analysing key account activities and conducting contractual...

2009-01-01

138

Mechanical properties, interface reactions and transport current densities of multi-core MgB_2/Ti/Cu/SS wire  

International Nuclear Information System (INIS)

Multi-core MgB_2/Ti/Cu/SS composite wire has been made by the in situ approach. Mechanical properties, interdiffusion reactions and critical currents were studied after heat treatments at temperatures between 500 and 850 "0C. Cu diffusion into the Ti layer occurs for all samples, resulting in the formation of intermetallic compounds at the Cu/Ti interface. EDX analysis has revealed the temperature dependence of all interface reactions. In spite of element reactions the critical current densities 10"5 A cm"-"2 and 10"4 A cm"-"2 were measured in liquid helium at magnetic fields 5 T and 9.5 T, respectively. 10"4 A cm"-"2 at 20 K is measured in an external field of 4 T.

2010-07-01

139

Optimization algorithm for linearity enhancement in the design of continuous-time sigma-delta modulators  

Science.gov (United States)

This paper proposes an optimization algorithm to reduce the distortion produced in the loop-filter of Continuous-Time Sigma-Delta Modulators. The aim of the algorithm is to find the loop-filter implementation that minimizes distortion at the output of the modulator, by modifying the output swing of every integrator. The algorithm is implemented in Matlab as an evolutive searching. During each step of the searching, the algorithm evaluates the harmonical distortion of a tone when it is applied to the modulator with a certain loop-filter implementation. The output of the algorithm is an optimum linear state-space representation of the loop-filter. This particular state-space representation leads to minimum distortion at the output of the modulator when the loop-filter is implemented with some specific circuitry previously defined. As long as the search is of evolutive type, the solution represents a local ...

2005-06-01

140

CAMAC 488 module: 68,000 based GPIB interface module  

Energy Technology Data Exchange (ETDEWEB)

What kind of hardware and software should be used to interface GPIB devices with the existing computer system. One idea was to use a commercially available Multibus card, BLC 8488 from National Semiconductor, whose on-board Z80 would manage the GPIB read/write functions and handshakes. With this card, one could make a hardware system which would consist of (1) CAMAC 080, (2) Multibus crate, (3) M. Shea's M68000, (4) M080, (5) BLC 8488 and (6) memory board. And the software considered for such a hardware package was GAS, which had been an established software package for communication between the ACNET computer system and smart CAMAC modules. However, a second idea was to put everything on a two-wide CAMAC module. The author pursued the second idea and came up with a two-wide CAMAC module called C488. The author describes the hardware - block diagrams, circuit blocks, front panel and hardware tests. He also refers ...

1985-03-01

141

A Plan to Diffuse Instructional Materials for Use by Transportation Educators.  

Science.gov (United States)

A plan to diffuse instructional modules for the preparation of transportation professionals is presented, based on research and demonstration projects sponsored by the Urban Mass Transportation Administration (UMTA). The diffusion/adoption plan involves: developing instructional modules; disseminating the modules to professors teaching transportation courses at the college level; promoting the use and adoption of the modules; and evaluating and revising the plan. Transportation educators teach in a variety of disciplines (e.g., engineering, public administration, urban planning, and technology). Eight design and evaluation criteria for the instructional modules are listed, along with the procedures used by West Virginia University in developing the five instructional modules. The diffusion strategy involves repackaging UMTA research findings, change agents, and ...

1986-01-01

142

Real time estimation of photovoltaic modules characteristics and its application to maximum power point operation  

Energy Technology Data Exchange (ETDEWEB)

In this paper, an approximate curve fitting method for photovoltaic modules is presented. The operation is based on solving a simple solar cell electrical model by a microcontroller in real time. Only four voltage and current coordinates are needed to obtain the solar module parameters and set its operation at maximum power in any conditions of illumination and temperature. Despite its simplicity, this method is suitable for low cost real time applications, as control loop reference generator in photovoltaic maximum power point circuits. The theory that supports the estimator together with simulations and experimental results are presented. (author)

2007-05-15

143

GPLS VME MODULE: A DIAGNOSTIC AND DISPLAY TOOL FOR NSLS MICRO SYSTEMS.  

Energy Technology Data Exchange (ETDEWEB)

The General Purpose Light Source VME module is an integral part of every front-end micro in the NSLS control system. The board incorporates features such as a video character generator, clock signals, time-of-day clock, a VME bus interrupter and general-purpose digital inputs and outputs. This module serves as a valuable diagnostic and real-time display tool for the micro development as well as for the final operational systems. This paper describes the functions provided by the board for the NSLS micro control monitor software.

1999-03-29

144

Fiber optic feedthrough module and method of making same  

International Nuclear Information System (INIS)

A fiber optic feedthrough module which comprises a metal sleeve, a fiber optic element extending through the sleeve in spaced relation thereto, and a tandem series of centrally-apertured mating annular sealant bodies of thermoplastic material surrounding the fiber optic element and compressed between it and the sleeve. The module is made by first providing a loose subassembly of a plurality of individual but interfitting sealant bodies on the fiber optic element and then inserting this subassembly into a metal sleeve, following by swaging the whole assembly which eliminates clearances and provides sealed interfaces between the various contacting components. (author).

1983-05-25

145

A new calculation of the cosmic-ray antiproton spectrum in the Galaxy and heliospheric modulation effects on this spectrum using a drift plus wavy current sheet model  

Energy Technology Data Exchange (ETDEWEB)

The expected interstellar antiproton spectrum arising from cosmic-ray interactions in the Galaxy is recalculated, and the modulation of both antiprotons and protons is calculated using a two-dimensional modulation model incorporating gradient and curvature drifts and a wavy current sheet as well as the usual diffusion, convection, and energy-loss effects. Significant differences in the antiproton/proton ratio for different solar magnetic field polarities are predicted as well as a 'low-energy' component for antiprotons below about 1 GeV. 28 refs.

1989-09-01

146

Structure design of human factor data management system for Daya Bay NPP  

International Nuclear Information System (INIS)

Collection, analysis and quantification of human factor data are important compositions of human reliability analysis (HRA) and probabilistic risk assessment (PRA). Various human factor databases have been set up, but there are comparatively little human factor data management systems which can be uses for collection, classification, analysis, calculation and predication of the human factor data. Therefore, the human factor data management system for Daya Bay NPP is developed, with the following three modules and four databases: original data module, computing module, introduced data module, and basic database, other data source of the plant, external database and introduced database. The foundational problems about human factor data and the systemic structure and function are described. The data structure in the database is also discussed, because it is of the most importance in the system

2000-04-01

147

Stress Tolerance of Photosystem II in Vivo  

UK PubMed Central (United Kingdom)

The in vivo photochemical activity of photosystem II was inferred from modulated chlorophyll fluorescence and photoacoustic measurements in intact leaves of several plant species (Lycopersicon...Full Text Available

1992-09-01

148

Splinter Protection for Airbase Firefighting Resources  

Science.gov (United States)

... 36 7 Corrugated Steel Pipe Concept Layout--Elevation ..... 37 viii ... revetment. 3. Land Use ... Corner modules and capping blocks are available. ...

1989-12-01

149

Salt modulates the stability and lipid binding affinity of the adipocyte lipid-binding proteins  

Science.gov (United States)

Adipocyte lipid-binding protein (ALBP or aP2) is an intracellular fatty acid-binding protein that is

2003-01-01

150

Purinergic receptors in the splanchnic circulation  

UK PubMed Central (United Kingdom)

There is considerable evidence that purines are vasoactive molecules involved in the regulation of blood flow. Adenosine is a well known vasodilator that also acts as a modulator of the response to...Full Text Available

2008-09-01

152

On the Impact of Longitudinal Breathing Motion Randomness for Tomotherapy Delivery  

UK PubMed Central (United Kingdom)

The purpose of this study is to explain the unplanned longitudinal dose modulations that appear in helical tomotherapy (HT) dose distributions in the presence of irregular patient breathing....Full Text Available

2008-09-21

153

Neuroprotective Actions of Brain Aromatase  

UK PubMed Central (United Kingdom)

The steroidal regulation of vertebrate neuroanatomy and neurophysiology includes a seemingly unending list of brain areas, cellular structures and behaviors modulated by these hormones. Estrogens,...Full Text Available

2009-07-01

154

Liquid nitrogen temperature operation of a switching power converter  

Science.gov (United States)

The performance of a 42/28 V, 175 W, 50 kHz pulse-width modulated buck dc/dc switching power

1995-01-01

155

Laboratory Description of Harbor Idealized Tests. Volume 1 ...  

Science.gov (United States)

... modules 2 and 3, 45 ft from each end) in a ... The toe of the stone revetment was 2 ft out from the ... in parentheses are for the current meters in layout 2. ...

1993-03-01

156

Is It Time To Give The US Engineer Battalion (Combat) (Heavy ...  

Science.gov (United States)

... revetment construction, water well drilling, mobile facility assets construction using ... five days, and establish site layout for the follow-on RH ... modules. ...

2001-02-01

157

Hypothalamic and dietary control of temperature-mediated longevity  

UK PubMed Central (United Kingdom)

Temperature is an important modulator of longevity and aging in both poikilotherms and homeotherm animals. In homeotherms, temperature homeostasis is regulated primarily in the preoptic area...Full Text Available

2010-01-01

158

High-power rf-pulsed modulators for the Los Alamos free-electron laser  

Energy Technology Data Exchange (ETDEWEB)

In the rf-driven free-electron laser (FEL) at the Los Alamos National Laboratory, there are two pulsed-power rf modulators as sources for two tandem, side-coupled 20-MeV linear accelerators. The rf power used to control the cavity fields is supplied by two 5.5-MW modulating anode klystrons operating at a center frequency of 1300.2 MHz. The modulation of the 125 kV klystron is achieved by using a triode switch tube that provides a pulse width up to 300 ..mu..s and a pulse repetition rate up to 10 Hz. This paper describes the present configuration of these two duplicate systems and presents plans for meeting the requirements of future rf FEL experiments at Los Alamos. 12 refs., 5 figs.

1987-09-01

159

Guideline for Sampling and Analysis of Tar and Particles in Biomass Producer Gases. Version 3.3  

Energy Technology Data Exchange (ETDEWEB)

This Guideline provides a set of procedures for the measurement of organic contaminants and particles in producer gases from biomass gasifiers. The procedures are designed to cover different gasifier types (updraft or downdraft fixed bed or fluidised bed gasifiers), operating conditions (0 - 900C and 0.6-60 bars) and concentration ranges (1 mg/m{sub n}{sup 3} to 300 g/m{sub n}{sup 3}). The Guideline describes a modular sampling train, and a set of procedures, which include: planning and preparation of the sampling, sampling and post-sampling, analysis, calculations, error analysis and reporting. The modular sampling train consists of 4 modules. Module 1 is a preconditioning module for isokinetic sampling and gas cooling. Module 2 is a particle collection module including a heated filter. Module 3 is a tar collection module with a gas quench ...

2002-07-01

160

Growth factor signalling in the regulation of -cell fate  

British Library Electronic Table of Contents (United Kingdom)

Glucagon plays critical roles in regulating glucose homeostasis, mainly by counteracting the effects of insulin. Consequently, the dysregulated glucagon secretion that is evident in type 2 diabetes has significant implications in the pathophysiology of the disease. Glucagon secretion from pancreatic -cells has been suggested to be modulated by blood glucose, signals from the nervous system and endocrine components. In addition to these regulators, intraislet factors acting in a paracrine manner from neighbouring -cells are emerging as central modulator(s) of -cell biology. One of the most important of these paracrine factors, insulin, modulates glucagon secretion. Indeed, the -cell-specific insulin receptor knockout (IRKO) mouse manifests hypersecretion of glucagon in the postprandial stag...

2011-01-01

161

FINAL REPORT CONTINUOUS SCANNING METEOROLOGICAL CAMERA SYSTEM FOR ...  

Science.gov (United States)

was deemed adequate and a cooling system designed utilizing the Melcor CP2-15- 10B thermoelectric module. Wall temperature achieved with this system was - 36 ...

162

Extensions to the VME hardware and software standards for the physics community  

Energy Technology Data Exchange (ETDEWEB)

With the ubiquitous availability of commercial VME modules and interface chips many experiments in all branches of Experimental Physics are turning to VME as the module packaging and backplane protocol of choice for application specific modules. The current VME backplane, electrical, and mechanical standards are clearly lacking when it comes to implementing the analogue and digital front end modules that Physics experiments rely on to provide the needed high speed and intelligent solutions to their data collection requirements. To address these needs the European ESONE and American VME-P committees are collaborating with the ANSII and ISO standards committees, and the VME VITA/VSO manufacturers associations, to define standard extensions to the VME protocols for such HEP needs as ``sparse data scans``, standard uses and implementations of previously user defined pins and connectors, standardization of ...

1995-10-01

163

Efficiency study of different photovoltaic plant connection schemes under dynamic shading  

Energy Technology Data Exchange (ETDEWEB)

An important growth in the power of the photovoltaic systems connected to a grid has recently been observed. In spite of the advances in module technology, the problems in the system design increased, especially regarding the surface of the earth they occupy. In this work we propose a complete model for plant simulation with different wiring diagrams and under dynamic shading. Results obtained from simulations showed that the configuration with the lowest performance was that of only one serial-parallel group, whereas the highest efficiency corresponded to a design of groups of modules in parallel connected then in series. In general, a higher efficiency was obtained diminishing the quantity of modules in series and increasing their number in parallel. The simulation model proposed allows exploring different alternatives of wiring modules and finding the most efficient configurations for photovoltaic ...

2010-06-15

164

Development status of Severe Accident Analysis Code SAMPSON  

International Nuclear Information System (INIS)

The Four years of the IMPACT, 'Integrated Modular Plant Analysis and Computing Technology' project Phase 1 have been completed. The verification study of Severe Accident Analysis Code SAMPSON prototype developed in Phase 1 was conducted in two steps. First, each analysis module was run independently and analysis results were compared and verified against separate-effect test data with good results. Test data are as follows: CORA-13 (FZK) for the Core Heat-up Module; VI-3 of HI/VI Test (ORNL) for the FP Release from Fuel Module; KROTOS-37 (JRC-ISPRA) for the Molten Core Relocation Module; Water Spread Test (UCSB) for the Debris Spreading Model and Benard's Melting Test for Natural Convection Model in the Debris Cooling Module; Hydrogen Burning Test (NUPEC) for the Ex-Vessel Thermal Hydraulics Module; PREMIX, PM10 (FZK) for the Steam Explosion ...

2000-11-01

165

Coupling calculation of CFD-ACE computational fluid dynamics code and DeCART whole-core neutron transport code for development of numerical reactor  

Energy Technology Data Exchange (ETDEWEB)

Code coupling activities have so far focused on coupling the neutronics modules with the CFD module. An interface module for the CFD-ACE/DeCART coupling was established as an alternative to the original STAR-CD/DeCART interface. The interface module for DeCART/CFD-ACE was validated by single-pin model. The optimized CFD mesh was decided through the calculation of multi-pin model. It was important to consider turbulent mixing of subchannels for calculation of fuel temperature. For the parallel calculation, the optimized decompose process was necessary to reduce the calculation costs and setting of the iteration and convergence criterion for each code was important, too.

2005-03-15

166

Compact ... - Earth Science Technology Office (ESTO) - NASA  

Science.gov (United States)

switch when this cavity matching condition is determined. This results is a ... MHz offset is provided by an acousto-optic modulator. (AOM). The AOM will be shut ...

167

Cholinergic modulation of multivesicular release regulates striatal synaptic potency and integration  

UK PubMed Central (United Kingdom)

The pleiotropic actions of neuromodulators on pre- and postsynaptic targets present challenges to disentangling the mechanisms underlying regulation of synaptic transmission. Within the striatum,...Full Text Available

2009-09-01

168

CAAX-box protein, prenylation process and carcinogenesis  

UK PubMed Central (United Kingdom)

CAAX proteins are widely involved in global cellular functions such as proliferation, differentiation, and carcinogenesis. As an important modulator of biological activity, signal transduction via protein...Full Text Available

169

Bonding of the Inner Tracker Silicon Microstrip Modules  

CERN Document Server

Microbonding of the CMS Tracker Inner Barrel (TIB) and Tracker Inner Disks (TID) modules was shared among six different Italian Institutes. The organization devised and the infrastructure deployed to handle this task is illustrated. Microbonding specifications and procedures for the different types of TIB and TID modules are given. The tooling specially designed and developed for these types of modules is described. Experience of production is presented. Attained production rates are given. An analysis of the microbonding quality achieved is presented, based on bond strengths measured in sample bond pull tests as well as on rates of bonding failures. Italian Bonding Centers routinely performed well above minimum specifications and a very low global introduced failure rate, at the strip level, of only $\\sim$0.015 \\% is observed.

2008-01-01

170

Benchmark analysis of rapid boron dilution transient by the PLASHY impact code  

International Nuclear Information System (INIS)

This paper describes the benchmark analysis results of Rapid Boron Dilution (RBD) transient tests. The RBD transient tests were carried out at University of Maryland. The data were obtained as a part of the International Standard Problem No. 43, ISP-43, for code assessment. Nuclear Power Engineering Corporation (NUPEC) participated the benchmark analysis of ISP443 with the PLASHY code. The PLASHY code is a general purpose single-phase fluid analysis code, developed by NUPEC. The code has two types of module, Cartesian/Cylindrical coordinate system module and BFC module. In order to reduce the computing time, the Cartesian/Cylindrical coordinate system module was employed. All calculations were done on a parallel computer, IBM SP2, by using the 12 of 76 CPU units. (author)

2000-10-01

171

Association and expression study of synapsin III and schizophrenia  

UK PubMed Central (United Kingdom)

The synapsin III gene, SYN3, which belongs to the family of synaptic vesicle-associated proteins, has been implicated in the modulation of neurotransmitter...Full Text Available

2009-11-20

172

A cost of energy comparison of single and multi cavity solar central receiver systems  

Energy Technology Data Exchange (ETDEWEB)

Variations in thermal energy costs of single module solar central receiver systems using one, two, three, and four aperture cavity receivers at a location corresponding to Barstow, California are investigated for nominal power ratings ranging from 100 MWt to 900 MWt. Also considered are the effects on energy costs of changes in plant latitude, and the energy cost impact of the replacement of the single module design with multiple connected modules producing the same thermal power. The results, obtained with the aid of the DELSOL2 computer program, indicate that solar central receiver plant energy costs are insensitive functions of power level, latitude, and configuration. No clear cost of energy advantage between single and multiple modules is seen.

1983-06-01

173

Telomerase-immortalized non-malignant human prostate epithelial cells retain the properties of multipotent stem cells  

International Nuclear Information System (INIS)

Understanding prostate stem cells may provide insight into the origin of prostate cancer. Primary cells have been cultured from human prostate tissue but they usually survive only 15-20 population doublings before undergoing senescence. We report here that RC-170N/h/clone 7 cells, a clonal cell line from hTERT-immortalized primary non-malignant tissue-derived human prostate epithelial cell line (RC170N/h), retain multipotent stem cell properties. The RC-170N/h/clone 7 cells expressed a human embryonic stem cell marker, Oct-4, and potential prostate epithelial stem cell markers, CD133, integrin #alpha#2#beta#1"h"i and CD44. The RC-170N/h/clone 7 cells proliferated in KGM and Dulbecco's Modified Eagle Medium with 10% fetal bovine serum and 5 #mu#g/ml insulin (DMEM + 10% FBS + Ins.) medium, and differentiated into epithelial stem cells that expressed epithelial cell markers, including CK5/14, CD44, p63 and cytokeratin 18 (CK18); as well as the mesenchymal cell ...

2008-01-01

174

Genome Sequence of a Lancefield Group C Streptococcus zooepidemicus Strain Causing Epidemic Nephritis: New Information about an Old Disease  

Science.gov (United States)

Outbreaks of disease attributable to human error or natural causes can provide unique opportunities to gain new information about host-pathogen interactions and new leads for pathogenesis research. Poststreptococcal glomerulonephritis (PSGN), a sequela of infection with pathogenic streptococci, is a common cause of preventable kidney disease worldwide. Although PSGN usually occurs after infection with group A streptococci, organisms of Lancefield group C and G also can be responsible. Despite decades of study, the molecular pathogenesis of PSGN is poorly understood. As a first step toward gaining new information about PSGN pathogenesis, we sequenced the genome of Streptococcus equi subsp. zooepidemicus strain MGCS10565, a group C organism that caused a very large and unusually severe epidemic of nephritis in Brazil. The genome is a circular chromosome of 2,024,171 bp. The genome shares extensive gene content, including many virulence factors, with genetically related group A ...

2008-08-21

175

XRF and PIXE method as trols for the element analysis of metallic glasses  

International Nuclear Information System (INIS)

The radionuclide X-ray fluorescence and particle induced X-ray emission methods were used for rapid and nondestructive analysis of metallic glasses. The methods were compared for accuracy and precision with the atomic absorption method. Some results of the analyses of Fe_xNi_8_0_-_xB_2_0 materials are briefly reviewed. The distribution of elements along the width as well as the length and a qualitative analysis of the composition of material surfaces are considered. (author).

1986-01-01

176

XRF and PIXE analysis of metallic glasses  

International Nuclear Information System (INIS)

Radionuclide X-ray fluorescence and particle induced X-ray emission methods were used for a rapid and nondestructive analysis of metallic glasses. The methods are compared in accuracy and precision with the atomic absorption method. Some results of analyses of Fe_xNi_8_0_-_xB_2_0 materials are briefly reviewed. The distribution of elements along the width and length, and a qualitative analysis of the composition of material surfaces are considered. (author) 3 refs.

1987-05-01

177

Widespread Dissemination of Aminoglycoside Resistance Genes armA and rmtB in Klebsiella pneumoniae Isolates in Taiwan Producing CTX-M-Type Extended-Spectrum ?-Lactamases ?  

UK PubMed Central (United Kingdom)

Among 235 extended-spectrum b2;-lactamase-producing Klebsiella pneumoniae (ESBL) isolates collected from a nationwide surveillance performed in Taiwan, 102 (43.4%) were...Full Text Available

2009-01-01

178

Transforming growth factor-? signaling mediates hypoxia-induced pulmonary arterial remodeling and inhibition of alveolar development in newborn mouse lung  

UK PubMed Central (United Kingdom)

Hypoxia causes abnormal neonatal pulmonary artery remodeling (PAR) and inhibition of alveolar development (IAD). Transforming growth factor (TGF)-b2; is an important regulator of lung development...Full Text Available

2008-07-01

179

The YTH Domain Is a Novel RNA Binding Domain*  

UK PubMed Central (United Kingdom)

The YTH (YT521-B homology) domain was identified by sequence comparison and is found in 174 different proteins expressed in eukaryotes. It is characterized by 14 invariant residues within an α-helix/b2;-sheet...Full Text Available

2010-05-07

180

TGFB1-Induced Extracellular Expression of TGFBIp and Inhibition of TGFBIp Expression by RNA Interference in a Human Corneal Epithelial Cell Line  

UK PubMed Central (United Kingdom)

Purpose.To report the increased production of extracellular transforming growth factor b2;-induced protein (TGFBIp) by human corneal epithelial cells (HCECs) after induction...Full Text Available

2011-02-01

181

Sinterable powders  

International Nuclear Information System (INIS)

A description is given of sinterable powders and methods of producing sintered products using such powders. The powders consist of (a) a particulate ceramic material, e.g. SiC, having specified particle size and surface area; (b) a carbon source material, e.g. sugar or a phenol-formaldehyde resin; and (c) a residue from a solution of H3BO3, B2O3, or mixtures of these as sintering aid. (U.K.).

182

Silver nanoparticles inhibit VEGF-and IL-1?-induced vascular permeability via Src dependent pathway in porcine retinal endothelial cells  

UK PubMed Central (United Kingdom)

The aim of this study is to determine the effects of silver nanoparticles (Ag-NP) on vascular endothelial growth factor (VEGF)-and interleukin-1 beta (IL-1b2;)-induced vascular permeability, and...Full Text Available

183

Purinergic receptors are involved in tooth-pulp evoked nocifensive behavior and brainstem neuronal activity  

UK PubMed Central (United Kingdom)

BackgroundTo evaluate whether P2X receptors are involved in responses to noxious pulp stimulation, the P2X3 and P2X2/3 receptor agonist α,b2;-methyleneATP...Full Text Available

184

Polygalacturonase ?-Subunit Antisense Gene Expression in Tomato Plants Leads to a Progressive Enhanced Wound Response and Necrosis in Leaves and Abscission of Developing Flowers  

UK PubMed Central (United Kingdom)

Tomato (Lycopersicon esculentum var. Better Boy) plants were transformed with a tomato leaf wound-inducible polygalacturonase (PG) b2;-subunit gene in the antisense orientation...Full Text Available

2003-10-01

185

Physiological effects of manipulating the level of insulin-degrading enzyme in insulin-producing cells of Drosophila  

UK PubMed Central (United Kingdom)

Insulin-degrading enzyme (IDE) degrades insulin and other peptides, including the Ab2; peptide of Alzheimer’s disease. However, the mechanism by which IDE acts on its substrates...Full Text Available

2011-01-01

186

Nationwide Survey of CTX-M-Type Extended-Spectrum ?-Lactamases among Klebsiella pneumoniae Isolates in Slovenian Hospitals ?  

UK PubMed Central (United Kingdom)

Among 177 extended-spectrum b2;-lactamase-producing Klebsiella pneumoniae isolates collected from 11 Slovenian hospitals in 2005 and 2006, 60 (34%), from eight hospitals,...Full Text Available

2009-01-01

187

Molecular identification of CTX-M and blaOXY/K1 ?-lactamase genes in Enterobacteriaceae by sequencing of universal M13-sequence tagged PCR-amplicons  

UK PubMed Central (United Kingdom)

BackgroundPlasmid encoded blaCTX-M enzymes represent an important sub-group of class A b2;-lactamases causing the ESBL phenotype which is increasingly...Full Text Available

188

Medical i2b2 NLP Smoking Challenge: The A-Life System Architecture and Methodology  

UK PubMed Central (United Kingdom)

We describe the architecture of LifeCode® (A-Life Medical, Inc.), a natural language processing system for free-text clinical information extraction, our methodology in applying LifeCode®...Full Text Available

2008-01-01

189

Klebsiella pneumoniae Strains Producing Extended-Spectrum ?-Lactamases in Spain: Microbiological and Clinical Features?  

UK PubMed Central (United Kingdom)

Extended-spectrum b2;-lactamases (ESBL) of the CTX-M, SHV, and TEM families were recognized in 76 (67%), 31 (27%), and 6 (5%) isolates, respectively, among 162 ESBL-producing Klebsiella...Full Text Available

2011-03-01

190

Kinetic Parameters of Efflux of Penicillins by the Multidrug Efflux Transporter AcrAB-TolC of Escherichia coli?  

UK PubMed Central (United Kingdom)

The multidrug efflux transporter AcrAB-TolC is known to pump out a diverse range of antibiotics, including b2;-lactams. However, the kinetic constants of the efflux process, needed for the quantitative...Full Text Available

2010-05-01

191

Isomerization of 1-O-Indol-3-Ylacetyl-?-d-Glucose 1  

UK PubMed Central (United Kingdom)

The first compound in the series of reactions leading to the ester conjugates of indole-3-acetic acid (IAA) in kernels of Zea mays sweet corn is the acyl alkyl acetal, 1-O-indol-3-ylacetyl-b2;-d-glucose...Full Text Available

1990-09-01

192

Interferon-? expressed by a rabies virus-based HIV-1 vaccine vector serves as a molecular adjuvant and decreases pathogenicity  

UK PubMed Central (United Kingdom)

Type I interferon is important in anti-viral responses and in coordinating the innate immune response. Here we explore the use of interferon-b2; to adjuvant the response to a rabies virus...Full Text Available

2008-12-20

193

Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages  

UK PubMed Central (United Kingdom)

LRP1 is a type-1 transmembrane receptor that mediates the endocytosis of diverse ligands. LRP1 b2;-chain proteolysis results in release of sLRP1 that is present in human plasma. In this study,...Full Text Available

2010-10-01

194

Highly Ordered Spatial Organization of the Structural Long Noncoding NEAT1 RNAs within Paraspeckle Nuclear Bodies  

UK PubMed Central (United Kingdom)

Paraspeckles (PSPs) are nuclear bodies associated with the retention in the nucleus of specific mRNAs. Two isoforms of a long noncoding RNA (NEAT1_v1/Menε and NEAT1_v2/Menb2;)...Full Text Available

2010-11-15

195

Growth differentiation factor-9 stimulates progesterone synthesis in granulosa cells via a prostaglandin E2/EP2 receptor pathway  

UK PubMed Central (United Kingdom)

Growth differentiation factor-9 (GDF-9), an oocyte-secreted member of the transforming growth factor b2; superfamily, progesterone receptor, cyclooxygenase 2 (Cox2; Ptgs2), and the EP2 prostaglandin...Full Text Available

2000-08-29

196

Global analysis of estrogen receptor beta binding to breast cancer cell genome reveals an extensive interplay with estrogen receptor alpha for target gene regulation  

UK PubMed Central (United Kingdom)

BackgroundEstrogen receptors alpha (ERα) and beta (ERb2;) are transcription factors (TFs) that mediate estrogen signaling and define the hormone-responsive phenotype...Full Text Available

197

First Report of the Emergence of CTX-M-Type Extended-Spectrum ?-Lactamases (ESBLs) as the Predominant ESBL Isolated in a U.S. Health Care System?  

UK PubMed Central (United Kingdom)

CTX-M-type extended-spectrum b2;-lactamases (ESBLs) have become increasingly common worldwide, with the notable exception of the United States, where TEM- and SHV-type ESBLs have appeared to predominate....Full Text Available

2007-11-01

198

First Outbreak of Multidrug-Resistant Klebsiella pneumoniae Producing both SHV-12-Type Extended-Spectrum ?-Lactamase and DHA-1-Type AmpC ?-Lactamase at a Korean Hospital  

UK PubMed Central (United Kingdom)

PurposeCoexistence of different classes of b2;-lactamases in a single bacterial isolate may pose diagnostic and therapeutic challenges. We investigated a spread of Klebsiella...Full Text Available

2008-02-29

199

Extended Spectrum ?-Lactamases among Gram-negative bacteria of nosocomial origin from an Intensive Care Unit of a tertiary health facility in Tanzania  

UK PubMed Central (United Kingdom)

BackgroundResistance to third generation cephalosporins due to acquisition and expression of extended spectrum b2;-lactamase (ESBL) enzymes among Gram-negative bacteria is...Full Text Available

200

Evolution of a cluster of innate immune genes (?-defensins) along the ancestral lines of chicken and zebra finch  

UK PubMed Central (United Kingdom)

BackgroundAvian b2;-defensins (AvBDs) represent a group of innate immune genes with broad antimicrobial activity. Within the chicken genome, previous work identified 14 AvBDs...Full Text Available

201

Enzymic Synthesis of Indole-3-Acetyl-1-O-?-d-Glucose 1  

UK PubMed Central (United Kingdom)

The first enzyme-catalyzed reaction leading from indole-3-acetic acid (IAA) to the myo-inositol esters of IAA is the synthesis of indole-3-acetyl-1-O-b2;-d-glucose...Full Text Available

1988-12-01

202

Effects of exogenous female sex-steroid hormones on lymphocyte ?2-adrenoceptors in normal females  

UK PubMed Central (United Kingdom)

We have previously shown that lymphocyte b2;2-adrenoceptors (AR) are under cyclical control of sex-steroid hormones with greater receptor density during the luteal phase of the menstrual...Full Text Available

1996-05-01

203

Comparison of Human Serum Dopamine-?-Hydroxylase Levels by Radioimmunoassay and Enzymatic Assay  

UK PubMed Central (United Kingdom)

Human serum dopamine-b2;-hydroxylase (3,4-dihydroxyphenylethylamine, ascorbate:oxygen oxidoreductase, EC 1.14.17.1) has been measured in a normal adult population by both enzymatic assay and by...Full Text Available

1974-03-01

204

Chromosome-Encoded Ambler Class A ?-Lactamase of Kluyvera georgiana, a Probable Progenitor of a Subgroup of CTX-M Extended-Spectrum ?-Lactamases  

UK PubMed Central (United Kingdom)

A chromosome-encoded b2;-lactamase gene, cloned and expressed in Escherichia coli from Kluyvera georgiana reference strain CUETM 4246-74 (DSM 9408), encoded the...Full Text Available

2002-12-01

205

Chromosomal Integration of the Extended-Spectrum ?-Lactamase Gene blaCTX-M-15 in Salmonella enterica Serotype Concord Isolates from Internationally Adopted Children?  

UK PubMed Central (United Kingdom)

We report the emergence of Salmonella enterica isolates of serotype Concord (and its monophasic variant 6,7:l,v:-) producing the extended-spectrum b2;-lactamases (ESBLs) SHV-12...Full Text Available

2009-05-01

206

Besarhanamides A and B from the marine cyanobacterium Lyngbya majuscula  

British Library Electronic Table of Contents (United Kingdom)

Besarhanamides A (1) and B (2) are fatty acid amides purified from the marine cyanobacterium, Lyngbya majuscula, collected from Pulau Hantu, Singapore. The structure determination of these secondary metabolites was carried out using extensive 2D NMR spectral data as well as chemical manipulations including the Marfey's method. In addition, besarhanamide A exhibited moderate toxicity with LD50 at 13mM in the brine shrimp toxicity bioassay.

2008-01-01

207

Association between Handling of Pet Treats and Infection with Salmonella enterica Serotype Newport Expressing the AmpC ?-Lactamase, CMY-2  

UK PubMed Central (United Kingdom)

Resistance to the extended-spectrum cephalosporins can occur in Salmonella species via the production of extended-spectrum and AmpC b2;-lactamases. We describe human infections...Full Text Available

2003-10-01

208

Active Site of ?-Chymotrypsin Activation by Association-Desolvation  

UK PubMed Central (United Kingdom)

High reactivity toward α-chymotrypsin is observed for derivatives of b2;-arylpropionic acids of varied structure—L-α-acylamido compounds, D-cyclized compounds, and, now,...Full Text Available

1970-06-01

209

A New Metal-Binding Site for Yeast Phosphoglycerate Kinase as Determined by the Use of a Metal-ATP Analog  

UK PubMed Central (United Kingdom)

Suicide substrate b2;, γ-bidentate Rh(III)ATP (RhATP) was used to map the metal ion-binding site in yeast phosphoglycerate kinase (PGK). Cleavage of the RhATP-inactivated enzyme with...Full Text Available

1997-02-01

210

Verification of the Gaspar dose assessment module used in Maxigasp and Popgasp  

Energy Technology Data Exchange (ETDEWEB)

The GASPAR module utilized in MAXIGASP and POPGASP has been verified by hand calculations. The program operates as documented by the NRC [Eckerman et. al. 1980]. Equations used in the code to calculate downwind deposition rates, concentrations in air, on ground surfaces, and in vegetables, meat, and milk are provided in this report.

1992-12-31

211

The mGluR2 Positive Allosteric Modulator BINA Decreases Cocaine Self-Administration and Cue-Induced Cocaine-Seeking and Counteracts Cocaine-Induced Enhancement of Brain Reward Function in Rats  

UK PubMed Central (United Kingdom)

Metabotropic glutamate receptor 2/3 (mGluR2/3) agonists were shown previously to nonselectively decrease both cocaine- and food-maintained responding in rats. mGluR2 positive allosteric modulators (PAMs)...Full Text Available

2010-09-01

212

Surface-plasmon voltammetry using a gold grating  

Energy Technology Data Exchange (ETDEWEB)

Using a sensitive optical wavelength modulation technique the surface-plasmon excited on a gold grating surface immersed in sulfuric acid is studied at the same time as cyclic voltammetry is undertaken. Because of the optical sensitivity of the modulation technique significant optical effects are observed at potentials well below those at which any gross oxidation effects occur.

2010-09-29

213

Spin Modulation in Semiconductor Lasers  

CERN Document Server

We provide an analytic study of the dynamics of semiconductor lasers with injection (pump) of spin-polarized electrons, previously considered in the steady-state regime. Using complementary approaches of quasi-static and small signal analyses, we elucidate how the spin modulation in semiconductor lasers can improve performance, as compared to the conventional (spin-unpolarized) counterparts. We reveal that the spin-polarized injection can lead to an enhanced bandwidth and desirable switching properties of spin-lasers.

2010-01-01

214

Spectroscopic detection  

Energy Technology Data Exchange (ETDEWEB)

In embodiments, spectroscopic monitor monitors modulated light signals to detect low levels of contaminants and other compounds in the presence of background interference. The monitor uses a spectrometer that includes a transmissive modulator capable of causing different frequency ranges to move onto and off of the detector. The different ranges can include those with the desired signal and those selected to subtract background contributions from those with the desired signal. Embodiments of the system are particularly useful for monitoring metal concentrations in combustion effluent.

2003-01-01

215

Shaping pulses using frequency conversion with a modulated picosecond free electron laser  

Energy Technology Data Exchange (ETDEWEB)

Computer simulations and experiments indicate that we can shape the infrared picosecond pulses of the Mark III FEL in amplitude, frequency, and phase. Strongly modulated fundamental and second harmonic pulses have been generated by operating the Mark III FEL in the regime of strong sideband growth. In this paper, we present the results of simulations and experiments for second harmonic generation with fundamental inputs from 2 to 3 {mu}m.

1995-12-31

216

SHIELD certification package  

Energy Technology Data Exchange (ETDEWEB)

Certification as applied to existing computer codes includes the verification and validation process, placing the code in configuration control, establishing user qualification standards and training requirements. All software intended for use in critical calculations must be certified. This report is intended to fulfill the requirements for the certification of the SHIELD, SHLDED, GEDIT, GENPRT, FIPROD, FPCALC, and PROCES modules of the SHIELD system built February, 1992, by W.S. Parks. These modules are used for burnup, cooling, separate, and edit calculations.

1992-02-01

217

On the homology of exotic Springer fibers  

CERN Document Server

We determine the structure of the total homology groups of exotic Springer fibers as affine Weyl group representations. As applications, we provide single top/socle property of standard modules in the exotic Deligne-Langlands correspondence (except for root of unity case), an analogue of Verma's theorem, the coincidence of analytic/geometric gradings in the $C ^{\\infty}$-realization of anti-spherical modules of graded Hecke algebras of type $\\mathsf{BC}$ with unequal parameters, among others.

2011-01-01

218

Laser monitoring of the size and polarization of the gamma beams of #gamma##gamma# and e#gamma# colliders  

International Nuclear Information System (INIS)

It is proposed to measure the spot sizes and polarization of #gamma# beams of future #gamma#e and #gamma##gamma# colliders detecting e"+e"- pairs produced as a result of interaction of high energy #gamma# quanta with density modulated and not modulated laser photons. The quantum electrodynamics cross sections, necessary numerical results as well as a short comparison of the proposed method with some other methods are given. (orig.).

219

Influence of chemical substitutions on the charge instability of Formula Not Shown  

British Library Electronic Table of Contents (United Kingdom)

We study the influence of Sr substitutions on the structural counterpart of the MI transition of Formula Not Shown . When Sr content increases, the commensurate CDW modulation of pure Formula Not Shown is changed into an incommensurate short range modulation that we attribute to a charge ordering of the Formula Not Shown electrons. The same features are observed in S deficient samples.

2008-01-01

220

In vivo modulation of murine serum tumour necrosis factor and interleukin-6 levels during endotoxemia by oestrogen agonists and antagonists.  

UK PubMed Central (United Kingdom)

Oestrogen has been reported to modulate tumour necrosis factor (TNF), interleukin (IL)-1 and IL-6 cytokine levels in human mononuclear cell cultures. In the present study, the effects of exogenous oestrogen...Full Text Available

1995-09-01

221

Comparing two strategies of dynamic intensity modulated radiation therapy (dIMRT) with 3-dimensional conformal radiation therapy (3DCRT) in the hypofractionated treatment of high-risk prostate cancer  

UK PubMed Central (United Kingdom)

BackgroundTo compare two strategies of dynamic intensity modulated radiation therapy (dIMRT) with 3-dimensional conformal radiation therapy (3DCRT) in the setting of hypofractionated...Full Text Available

222

Adiabatic quantum computing with phase modulated laser pulses  

Energy Technology Data Exchange (ETDEWEB)

Implementation of quantum logical gates for multilevel systems is demonstrated through decoherence control under the quantum adiabatic method using simple phase modulated laser pulses. We make use of selective population inversion and Hamiltonian evolution with time to achieve such goals robustly instead of the standard unitary transformation language. (letter to the editor)

2005-09-23

223

17th Workshop on Crystalline Silicon Solar Cells and Modules: Materials and Processes; Workshop Proceedings  

Energy Technology Data Exchange (ETDEWEB)

The National Center for Photovoltaics sponsored the 17th Workshop on Crystalline Silicon Solar Cells & Modules: Materials and Processes, held in Vail, CO, August 5-8, 2007. This meeting provided a forum for an informal exchange of technical and scientific information between international researchers in the photovoltaic and relevant non-photovoltaic fields. The theme of this year's meeting was 'Expanding Technology for a Future Powered by Si Photovoltaics.'

2007-08-01

224

Photovoltaic performance and reliability workshop  

Energy Technology Data Exchange (ETDEWEB)

This proceedings is the compilation of papers presented at the ninth PV Performance and Reliability Workshop held at the Sheraton Denver West Hotel on September 4--6, 1996. This years workshop included presentations from 25 speakers and had over 100 attendees. All of the presentations that were given are included in this proceedings. Topics of the papers included: defining service lifetime and developing models for PV module lifetime; examining and determining failure and degradation mechanisms in PV modules; combining IEEE/IEC/UL testing procedures; AC module performance and reliability testing; inverter reliability/qualification testing; standardization of utility interconnect requirements for PV systems; need activities to separate variables by testing individual components of PV systems (e.g. cells, modules, batteries, inverters,charge controllers) for individual reliability and then test them in ...

1996-10-01

225

Optical modules for the neutrino telescope KM3NeT  

Energy Technology Data Exchange (ETDEWEB)

KM3NeT is a future deep-sea research infrastructure hosting a neutrino telescope with a volume of at least one cubic kilometer to be constructed in the Mediterranean Sea. The experiment aims to detect high-energy cosmic neutrinos using a 3D array of optical modules to collect the Cherenkov light induced by charged particles in the water. Upward going muons and showers produced in neutrino interactions with the surrounding matter will allow the search and study of possible sources of extra-terrestrial neutrinos. The design of optical modules makes an important impact on the performance and cost of the KM3NeT project. Several different optical module configurations are under consideration; based on glass pressure spheres containing: a large (10 in.) hemispherical photomultiplier tube (with a multi-anode version as an option); 25-31 3 in. photomultiplier tubes, or a crystal scintillator-based hybrid device (X-HPD). The ...

2010-11-01

226

Development of flame retardant PV module encapsulants: Volume 1. Final report  

Energy Technology Data Exchange (ETDEWEB)

This Phase 1 final report covers the work performed by Springborn Testing and Research, Inc., for the period October 1, 1997 to June 30, 1998 under the Department of Energy Cooperative Agreement Number DE-FC36-97GO10255, entitled Development of Flame Retardant PV Module Encapsulants. While use of roof-mounted arrays has always been an attractive means of deploying PV, only within recent years have such building integrated concepts (BIPV) found renewed interest among module makers and end-users. Prior to building integrated and rooftop applications, flammability requirements for modules have not been a great industry concern. However, with growing interest in BIPV and the requirement for building code requirements for commercial and industrial structures, flammability issues have become a barrier to entry for many module constructions into this potentially huge domestic market for PV. The overall goal of ...

1998-06-01

227

Using Multimedia Learning Modules in a Hybrid-Online Course in Electricity and Magnetism  

Science.gov (United States)

We have been piloting web-based multimedia learning modules (MLMs), developed by the Physics Education Research Group at the University of Illinois at Urbana Champaign (UIUC), as a "prelecture assignment" in several introductory physics courses at California State Polytechnic University at Pomona. In this study, we report the results from a controlled study utilizing modules on electricity and magnetism as a part of a blended hybrid-online course. We asked students in the experimental section to view the MLMs prior to attending the face-to-face class, and to make sure this would not result in additional instructional time, we reduced the weekly class time by one-third. We found that despite reduced class time, student-learning outcomes were not hindered; in fact, the implementation of the UIUC MLMs resulted in a positive effect on student performance on conceptual tests and classroom discussion questions. (Contains 4 figures and 1 table.)

2010-12-01

228

User's guide for the BNW-III optimization code for modular dry/wet-cooled power plants  

Energy Technology Data Exchange (ETDEWEB)

This user's guide describes BNW-III, a computer code developed by the Pacific Northwest Laboratory (PNL) as part of the Dry Cooling Enhancement Program sponsored by the US Department of Energy (DOE). The BNW-III code models a modular dry/wet cooling system for a nuclear or fossil fuel power plant. The purpose of this guide is to give the code user a brief description of what the BNW-III code is and how to use it. It describes the cooling system being modeled and the various models used. A detailed description of code input and code output is also included. The BNW-III code was developed to analyze a specific cooling system layout. However, there is a large degree of freedom in the type of cooling modules that can be selected and in the performance of those modules. The costs of the modules are input to the code, giving the user a great deal of flexibility.

1984-09-01

229

The envelope order spectrum based on generalized demodulation time-frequency analysis and its application to gear fault diagnosis  

British Library Electronic Table of Contents (United Kingdom)

The generalized demodulation time-frequency analysis is a novel signal processing method, which is particularly suitable for the processing of multi-component amplitude-modulated and frequency-modulated (AM-FM) signals as it can decompose a multi-component signal into a set of single-component signals whose instantaneous frequencies own physical meaning. While fault occurs in gear, the vibration signals measured from gearbox would exactly display AM-FM characteristics. Therefore, targeting the modulation feature of gear vibration signal in run-ups and run-downs, a fault diagnosis method in which generalized demodulation time-frequency analysis and envelope order spectrum technique are combined is put forward and applied to the transient analysis of gear vibration signal. Firstly the multi-...

2010-01-01

230

Recent advances in silicon-germanium alloy technology and an assessment of the problems of building the modules for a radioisotope thermoelectric generator  

International Nuclear Information System (INIS)

This paper reviews the state of the art of silicon-germanium technology and assesses the problems of building thermoelectric modules in Europe, based upon silicon-germanium alloys, for use in multihundred watt radio-isotope thermoelectric generator. The generator developed in the United States for the International Solar Polar mission has been used as a reference system. The essential features of an alternative system, which employs thermocouples fabricated from improved silicon-germanium alloys based upon a design by the Fairchild Space and Electronics Company, is also described. It is concluded that although the fabrication of reliable electrical contacts will present a major problem, the technology is available in Europe to build thermoelectric modules similar to those developed for the International Solar Polar mission. (orig.).

231

PLZT spatial light modulator for a 1-D hologram memory.  

Science.gov (United States)

A 100-bit slitlike aperture array spatial light modulator has been developed using 8.8/65/35 PLZT for a high-bit-density 1-D hologram memory. The most desirable characteristics, such as distortion-free diffraction-limited Fourier transform patterns and good uniformity of displayed bit patterns over 100 bits, have been realized. The lowest SNR was 86, and rise time and fall time have been 30 microsec and 8 microsec, respectively, at 190-V halfwave voltage. One-dimensional holographic storage experiments have been successfully performed using this PLZT spatial light modulator. PMID:20216813

1980-01-01

232

Negative frequency and complex-carrier modulation and demodulation  

CERN Document Server

Negative frequency has a physical meaning, the complete description of a frequency signal is a rotating complex signal, in complete description, positive frequency signal exp(iwt) and negative frequency signal exp(-iwt) is two distinguishable and independent frequency signals. Because the real-carrier modulation and demodulation do not distinguish positive and negative frequency, so half of the spectrum resources and signal energy are wasted. The complex-carrier modulation uses the distinguishable positive frequency signal exp(iwt) and negative frequency signal exp(-iwt) as the carrier signals, they can carry different information, so the spectrum resources is full used, the complex-carrier demodulation does not lose signal energy, so the spectrum efficiency is improved.

2010-01-01

233

Manufacture and first wall joining for an ITER primary wall module prototype: R and D phase with small scale mock-ups  

International Nuclear Information System (INIS)

In the frame of the Primary Wall Module prototype manufacturing for ITER, a consistent R and D phase was conducted in order to identify the industrial allowable tolerances and manufacturing problems which would occur when joining pieces by HIPping process during the PW module manufacturing. The purpose of this development was to give as industrial as possible manufacturing routes for joining together large Stainless Steel or DS-Copper pieces with Stainless Steel tubes and for bonding Beryllium tiles onto a curved component surface. The study concerned surface preparations, allowable gaps and joint geometry, Beryllium tile geometry, Titanium interlayer thickness, etc. This R and D phase also allowed the development and validation of different ultrasonic inspection tools needed for plate-plate, tube-plate, edge to edge plate bonding.

2001-10-01

234

High concentration low wattage solar arrays and their applications  

Energy Technology Data Exchange (ETDEWEB)

Midway Labs currently produces a 335x concentrator module that has reached as high as 19{percent} active area efficiency in production. The current production module uses the single crystal silicon back contact SunPower cell. The National Renewable Energy Lab has developed a multi junction cell using GalnP/GaAs technologies. The high efficiency ({gt}30{percent}) and high cell voltage offer an opportunity for Midway Labs to develop a tracking concentrator module that will provide 24 volts in the 140 to 160 watt range. This voltage and wattage range is applicable to a range of small scale water pumping applications that make up the bulk of water pumping solar panel sales. {copyright} {ital 1997 American Institute of Physics.}

1997-02-01

235

External quality control for immunocytochemistry on cytology samples: a review of UK NEQAS ICC (cytology module) results  

British Library Electronic Table of Contents (United Kingdom)

I. S. Kirbis, P. Maxwell, M. S. Flear, K. Miller and M. Ibrahim External quality control for immunocytochemistry on cytology samples: a review of UK NEQAS ICC (cytology module) results Objective:- To date, external quality control for immunocytochemistry on cytology samples is provided only by the United Kingdom national external quality assessment service for immunocytochemistry and in situ hybridisation (UK NEQAS ICC & ISH). For the purpose of this study a retrospective analysis of a comprehensive collection of quality-related data regarding immunocytochemistry on cytology samples collected through this service was analysed. Methods:- The quality of immunocytochemical reactions, using on-line collected data, was analysed for the last 23 UK NEQAS ICC cytology module external quality asses...

2011-01-01

236

Development of process technology for large-area thin-film solar modules based on compound semiconductors. Final report; Entwicklung der technologischen Grundlagen fuer grosse Photovoltaikmodule auf Basis von Duennschicht-Verbindungshalbleitern. Abschlussbericht  

Energy Technology Data Exchange (ETDEWEB)

A cooperative effort of the Center for Solar Energy and Hydrogen Research (ZSW) and Phototronics Solartechnik GmbH (PST) aimed at the transfer of highly efficient solar cells developed on a laboratory scale, to large-area thin-film solar modules suitable for production. This work was based on research and development at the Institute for Physical Electronics (IPE) of Stuttgart University and ZSW on one hand, and on the know-how of PST in regard to large-area module fabrication on the other hand. The various thin-film layers of the cells and modules comprize molybdenum as rear contact, copper-indium(gallium)-diselenide (CIGS) as absorber material, the combination of cadmium sulphide (CdS) and ZnO as window layer. To produce these layers on large areas (30x30 cm{sup 2}), equipment was constructed and procedures were developed. Monolithic series connection of cells, used in other thin-film technologies, was studied and ...

1998-06-01

237

Demonstration of zinc/air fuel battery to enhance the range and mission of fleet electric vehicles: Preliminary results in the refueling of a multicell module  

Energy Technology Data Exchange (ETDEWEB)

We report progress in an effort to develop and demonstrate a refuelable zinc/air battery for fleet electric vehicle applications. A refuelable module consisting of twelve bipolar cells with internal flow system has been refueled at rates of nearly 4 cells per minute refueling time of 10 minutes for a 15 kW, 55 kWh battery. The module is refueled by entrainment of 0.5-mm particles in rapidly flowing electrolyte, which delivers the particles into hoppers above each cell in a parallel-flow hydraulic circuit. The concept of user-recovery is presented as an alternative to centralized service infrastructure during market entry.

1994-08-08

238

Susceptible gene single nucleotide polymorphism and hemorrhage risk in patients with brain arteriovenous malformation  

British Library Electronic Table of Contents (United Kingdom)

The relationship between single nucleotide polymorphism (SNP) of interleukin-17 (IL-17A), transforming growth factor @b (TGF-@b), as well as its receptor (TGFR-@b2) and susceptibility to intracerebral hemorrhage in patients with brain arteriovenous malformation (BAVM) was investigated in the present study. A total of 53 patients with BAVM and 120 healthy controls were recruited, all of whom were Han Chinese from South China. There were no statistically significant differences in the IL-17A-197 guanine/adenine (G/A) or TGF-@b1-509 cytosine/thymine (C/T) genotypes or gene frequencies between BAVM patients and controls (p>0.05), but the gene frequency of the TGFR-@b2-875 A/G genotype in patients with BAVM was significantly higher (p<0.05). Furthermore, the frequencies of the G allele of IL-17...

2011-01-01

239

Spectroscopic properties of Er"3"+ ions in cadmium and alkali cadmium borosulphate glasses  

International Nuclear Information System (INIS)

Spectroscopic properties of Er"3"+ : CBS (CdSO_4 + B_2O_3 and R_2SO_4 + CdSO_4 + B_2O_3, R_2SO_4 = Li_2SO_4.H_2O, Na_2SO_4, K_2SO_4 and Gd_2(SO_4)_3.8H_2O) glasses are reported. The assigned energy level data of Er"3"+(4f"1"1) in these glasses are analysed in terms of a parametrized model Hamiltonian. The standard deviations of the data fits are between 39 and 47 cm"-"1 so that the energy level schemes of the Er"3"+(4f"1"1) ions in borosulphate (CBS) glasses are reasonably well reproduced. Radiative properties for the fluorescent levels of Er"3"+ : CBS glasses are determined by using the Judd-Ofelt theory. The potential laser transitions are identified with the help of predicted radiative properties which are compared and discussed with similar results. (author).

1997-01-01

240

Molybdenum complexes of biochemical interest. New coordination complexes of oxomolybdenum(V) with the tridentate ONO donor Schiff bases derived from salicylaldehydes and ethanolamine  

International Nuclear Information System (INIS)

New oxomolybdenum(V) complexes MoOClL (where LH_2 = Schiff base) derived from ethanolamine and salicylaldehyde, 5-chlorosalicylaldehyde, 5-bromosalicylaldehyde, 5-nitrosalicylaldehyde, 3-ethoxysalicylaldehyde and 2-hydroxy-1-naphthaldehyde have been synthesized and characterised by elemental analyses, conductance, molecular weight, i.r. and electronic spectra and magnetic measurements. The Schiff bases behave as dibasic tridentate ONO donor ligands. The complexes are non-electrolytes and dimers. The complexes exhibit subnormal magnetic moments and are involved in antiferromagnetic exchange with S = 0 ground state. The complexes exhibit electronic spectral bands at ca. 13000 and ca. 17000 cm"-"1 due to the transitions dsub(xy)->dsub(xz,yz) ("2B_2->"2E) and dsub(xy)->dsub(x2-y2) ("2B_2->"2B_1), respectively. The #nu#(Mo=O) frequency of the complexes is observed in the 900-970 cm"-"1 region. On ...

1985-01-01

241

Microstructural development inside the stress induced martensite variant in a Ti-Ni-Nb shape memory alloy  

Energy Technology Data Exchange (ETDEWEB)

The microstructural development inside the stress induced martensite (SIM) variants in Ti-Ni-Nb alloy with various degrees of deformation have been revealed by electron microscopic observations. The orientation relationship between the SIM and the parent phase has been found: [1{bar 1}0]{sub M}{parallel}[11{bar 1}]{sub B2}, (001){sub M} 5{degree} away from (101){sub B2}. The lattice invariant shear of the SIM variants at the slightly deformed stage is dominantly (11{bar 1}) Type I twin. Besides the ordinary slip, the adjustment and development of the internal secondary twinning from (11{bar 1}) Type I twin to {l_angle}011{r_angle} Type II/ or (011) Type I twin, (001)compound twin and (111) Type I twin happen concurrently or in combination inside the SIM variants with the further deformation. The corresponding deformation mechanisms include stress induced reorientation of SIM substructural bands by the ...

2000-04-03

242

Electrical breakdown at low pressure in the presence of a weak magnetic field  

Energy Technology Data Exchange (ETDEWEB)

Electron trapping in crossed electric and magnetic fields is an important mechanism by which electrical discharges can develop in low pressure gases. The authors report observations of discharges produced by this mechanism around a spherical anode in two space simulation chambers, namely the Space Plasma Interaction Experiment (SPIE) at the University of Maryland, and the NASA-Lewis B-2 chamber. They have identified two types of discharges in these experiments. In the B-2 chamber, the breakdown takes the form of a runaway dischage with spherical topology, limited only by the ability of the power supply to provide the current. In the SPIE chamber this type of discharge also occurs, in addition to a low current toroidal discharge which is observed at higher magnetic fields. They present measurements of both types of discharge and show how the trapping effect of the magnetic field together with secondary ...

1990-05-01

243

EPR, optical, infrared and Raman studies of VO"2"+ ions in polyvinylalcohol films  

International Nuclear Information System (INIS)

Electron paramagnetic resonance (EPR), optical, infrared and Raman spectral studies have been carried out on vanadyl ions doped in polyvinylalcohol (PVA) films. The spin-Hamiltonian parameters (g and A) and the molecular orbital coefficients (#beta#_2"*"2 and k) have been evaluated. The values of spin-Hamiltonian parameters confirm that the vanadyl ions are present in PVA films as VO"2"+ molecular ions in an octahedral site with a tetragonal compression (C_4_v). The temperature variation EPR studies reveal that the variation of number of spins with temperature is in accordance with Boltzmann law. It is interesting to observe that the variation of susceptibility with temperature obeys Curie-Weiss law. The FT-IR and FT-Raman spectrum exhibits few bands, which are attributed to O-H, C-H, C-C and C-O groups of stretching and bending vibrations. The optical absorption spectrum exhibits two bands, which are assigned to "2B_2_g->"2B_1_g and ...

2007-01-15

244

Crystal electric field excitations in the cerium compound CeRh_3B_2 studied by inelastic neutron scattering  

International Nuclear Information System (INIS)

We have performed inelastic neutron scattering (INS) experiments on CeRh_3B_2 at various temperatures to obtain direct information on the crystal electric field (CEF) in this compound, which exhibits some very peculiar magnetic properties for a Ce system: it is ferromagnetic with an unusually high Curie temperature (115 K), which contrasts with a strongly reduced and anisotropic magnetization (0.4 #mu#_B/fu within the c-plane of the hexagonal structure). Measurements with high incident energies show only one well defined magnetic excitation around 150 meV, its exact position varying with the temperature. These results, combined with our previous data of magnetization and magnetic form factor, have permitted us to determine the CEF energy level scheme taking into account the two J multiplets of the Ce"3"+ ion. Information on the ground state (quasielastic contribution and ground state moment) has also been obtained by experiments at low incident ...

2007-12-19

245

Assessment of epidermal growth factor receptor (EGFR, ErbB1) and HER2 (ErbB2) protein expression levels and response to lapatinib (Tykerb, GW572016) in an expanded panel of human normal and tumour cell lines  

British Library Electronic Table of Contents (United Kingdom)

Abstract. Objective: Lapatinib (Tykerb, GW572016), a potent inhibitor of the catalytic activities of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) (ErbB2), inhibits population growth of selected EGFR and HER2 overexpressing cell lines. Previous studies with a small number of cell lines suggest a correlation between overexpression of EGFR and/or HER2 and sensitivity to growth inhibition by lapatinib; however, the precise determinants of lapatinib selectivity for tumour and/or other cells remain unclear. Materials and methods: To clarify the determinants of its selectivity in cultured cells, lapatinib-induced cell population growth inhibition and relative EGFR and HER2 protein expression were quantified in 61 different human tumour cell lines fro...

2007-01-01

246

Two new paeciloxocins from a mangrove endophytic fungus Paecilomyces sp.  

British Library Electronic Table of Contents (United Kingdom)

Paeciloxocins A and B (2-(1-hydroxy-3-methylbutyl)- and 2-(1-acetoxy-3-methylbutyl)- 11-hydroxy-9-methyl-1-methoxy-5H,7H-dibenzo[b,g]-1,5-dioxocin-5-ones), viz., two new metabolites, were isolated from the mangrove fungus Paecilomyces sp. collected from the Taiwan Strait. Their structures were elucidated by spectral methods. Paeciloxocin A exhibited strong cytotoxicity against the hepG2 cell line.

2010-01-01

247

PDS_VERSION_ID = PDS3 FILE_NAME = "M1102254.IMQ" RECORD_TYPE ...  

Science.gov (United States)

UUv/4sQ d92aa%bvBR 6C7*?+'dI 1Yy! bd*O NdmD $t6b ,2Bw P,. ...... a] ULtd *w rD*M>93y eLeh "l;BdDCd u$g4rA&[` 3zD# a%robOT 9y[1 "$ngz f&6|D&" /(KUH() fG$f ...

248

Simulation of dopant diffusion and activation during flash lamp annealing  

International Nuclear Information System (INIS)

A set of advanced models implemented into the simulator Sentaurus Process was applied to simulate ultra shallow junction formation by flash lamp annealing (FLA). The full path transient enhanced diffusion model includes equations for small interstitial clusters (I_2, I_3, I_4), #left brace#3 1 1#right brace# defects and dislocation loops. A dopant-point defect clustering model is used for dopant activation simulation. Several cluster types are considered: B_2, B_2I, B_2I_2, B_3I, B_3I_2, B_3I_3 for boron and As_2, As_2V, As_3, As_3V, As_4, As_4V for arsenic. Different point defect and dopant-point defect pair charge states are taken into account to obtain accurate results in the high doping level region. The flux expressions in the three-phase segregation model include a dependence on the doping level and point defect supersaturation. The FLA process was ...

2008-12-05

249

Assessment of the PIUS physics and thermal-hydraulic experimental data bases  

Energy Technology Data Exchange (ETDEWEB)

The PIUS reactor utilizes simplified, inherent, passive, or other innovative means to accomplish safety functions. Accordingly, the PIUS reactor is subject to the requirements of 10CFR52.47(b)(2)(i)(A). This regulation requires that the applicant adequately demonstrate the performance of each safety feature, interdependent effects among the safety features, and a sufficient data base on the safety features of the design to assess the analytical tools used for safety analysis. Los Alamos has assessed the quality and completeness of the existing and planned data bases used by Asea Brown Boveri to validate its safety analysis codes and other relevant data bases. Only a limited data base of separate effect and integral tests exist at present. This data base is not adequate to fulfill the requirements of 10CFR52.47(b)(2)(i)(A). Asea Brown Boveri has stated that it plans to conduct more separate effect and ...

1993-12-31

250

A technique for determining the spatial and temporal distributions of surface fluxes of heat and moisture over the Southern Great Plains Cloud and Radiation Testbed  

Energy Technology Data Exchange (ETDEWEB)

Land surface parameterization schemes such as the Simple Biosphere Model (SiB2) have found considerable use in climate simulation models, where they provide lower boundary conditions in the form of surface sensible and latent heat fluxes. A methodology is described to apply models of this type at high resolution, using data from the Department of Energy{close_quote}s Cloud and Radiation Testbed in Oklahoma and Kansas, to determine the spatial variations of heat fluxes over the domain and to determine area-weighted flux averages for use in single-column model studies. Data from a dense array of meteorological instruments are interpolated to provide the wind, temperature, vapor pressure, radiation, and precipitation values needed by SiB2. The state of the vegetation is characterized through the use of the normalized difference vegetation index determined from satellites. The performance of the ...

1998-03-01

251

Understanding Enzyme Activity Using Single Molecule Tracking (Poster)  

Energy Technology Data Exchange (ETDEWEB)

This poster describes single-molecule tracking and total internal reflection fluorescence microscopy. It discusses whether the carbohydrate-binding module (CBM) moves on cellulose, how the CBM binds to cellulose, and the mechanism of cellulosome assembly.

2009-06-01

252

Triosephosphates Modulate Leaf Mitochondrial Phosphorylation by Inhibition and Uncoupling of Electron Transport 1  

UK PubMed Central (United Kingdom)

The effect of TP (triosephosphates:glyceraldehyde-3 phosphate, GAP, +dihydroxyacetone phosphate, DHAP) on respiration, phosphorylation and matrix ATP/ADP ratios of isolated oat mesophyll mitochondria...Full Text Available

1985-11-01

253

Top-down and bottom-up modulation in processing bimodal face/voice stimuli  

UK PubMed Central (United Kingdom)

BackgroundProcessing of multimodal information is a critical capacity of the human brain, with classic studies showing bimodal stimulation either facilitating or interfering in perceptual...Full Text Available

254

Time-limited modulation of appetitive Pavlovian memory by D1 and NMDA receptors in the nucleus accumbens  

UK PubMed Central (United Kingdom)

Recent research has implicated the nucleus accumbens (NAc) in consolidating recently acquired goal-directed appetitive memories, including spatial learning and other instrumental processes. However,...Full Text Available

2005-04-26

255

The use of EPID-measured leaf sequence files for IMRT dose reconstruction in adaptive radiation therapy  

UK PubMed Central (United Kingdom)

For intensity modulated radiation treatment (IMRT) dose reconstruction, multileaf collimator (MLC) log files have been shown applicable for deriving delivered fluence maps. However, MLC log files are...Full Text Available

2008-11-01

256

The requirement of yeast replication origins for pre-replication complex proteins is modulated by transcription  

UK PubMed Central (United Kingdom)

The mini-chromosome maintenance proteins Mcm2–7 are essential for DNA replication. They are loaded onto replication origins during G1 phase of the cell cycle to form a pre-replication complex...Full Text Available

2005-01-01

257

The opiorphin gene (ProL1) and its homologues function in erectile physiology  

UK PubMed Central (United Kingdom)

OBJECTIVETo determine if ProL1, a member of the opiorphin family of genes, can modulate erectile physiology, as it encodes a peptide which acts as...Full Text Available

2008-09-01

258

The implication of Sir2 in replicative aging and senescence in Saccharomyces cerevisiae  

UK PubMed Central (United Kingdom)

The target of rapamycin (TOR) pathway regulates cell growth and aging in various organisms. In Saccharomyces cerevisiae, silent information regulator 2 (Sir2) modulates cellular senescence. Moreover,...Full Text Available

259

The detection of spiral arm modulation in the stellar disk of an optically flocculent and an optically grand design galaxy  

CERN Document Server

Two dimensional Fourier spectra of near-infrared images of galaxies provide a powerful diagnostic tool for the detection of spiral arm modulation in stellar disks. Spiral arm modulation may be understood in terms of interference patterns of outgoing and incoming density wave packets or modes. The brightness along a spiral arm will be increased where two wave crests meet and constructively interfere, but will be decreased where a wave crest and a wave trough destructively interfere. Spiral arm modulation has hitherto only been detected in grand design spirals (such as Messier 81). Spiral arm amplitude variations have the potential to become a powerful constraint for the study of galactic dynamics. We illustrate our method in two galaxies: NGC 4062 and NGC 5248. In both cases, we have detected trailing and leading m=2 waves with similar pitch angles. This suggests that the amplification mechanism is the WASER type II. In this ...

2000-01-01

260

The Fermilab Linac Upgrade  

Energy Technology Data Exchange (ETDEWEB)

The Fermilab Linac Upgrade is planned to increase the energy of the H- linac from 200 to 400 MeV. This is intended to reduce the incoherent space-charge tuneshift at injection into the 8 GeV Booster which can limit either the brightness or the total intensity of the beam. The Linac Upgrade will be achieved by replacing the last four 201.25 MHz drift-tube tanks which accelerate the beam from 116 to 200 MeV, with seven 805 MHz side-coupled cavity modules operating at an average axial field of abut 7.5 MV/m. This will allow acceleration to 400 MeV in the existing Linac enclosure. Each accelerator module will be driven with a klystron-based rf power supply. A prototype rf modulator has been built and tested at Fermilab, and a prototype 12 MW klystron is being fabricated by Litton Electron Devices. Fabrication of production accelerator modules is in progress. 8 figs., 4 tabs.

1991-02-01

261

Temperature regulates limb length in homeotherms by directly modulating cartilage growth  

UK PubMed Central (United Kingdom)

Allen's Rule documents a century-old biological observation that strong positive correlations exist among latitude, ambient temperature, and limb length in mammals. Although genetic selection for thermoregulatory...Full Text Available

2008-12-09

262

Synchrony between orientation-selective neurons is modulated during adaptation-induced plasticity in cat visual cortex  

UK PubMed Central (United Kingdom)

BackgroundVisual neurons respond essentially to luminance variations occurring within their receptive fields. In primary visual cortex, each neuron is a filter for stimulus features...Full Text Available

263

Successful Launches to Orbit on U.S. Launch Vehicles  

Science.gov (United States)

Milstar 2. (USA 115). 60A. Titan IV. Nov. 12, 1995. Install Docking Module on the Mir space. 396 km. Second of 9 planned flights. Space Shuttle Atlantis ...

264

SH2-B Is Required for Both Male and Female Reproduction  

UK PubMed Central (United Kingdom)

Many growth factors and hormones modulate the reproductive status in mammals. Among these, insulin and insulin-like growth factor I (IGF-I) regulate the development of gonadal tissues. SH2-B has been...Full Text Available

2002-05-01

265

Rate of Dehydration and Cumulative Desiccation Stress Interacted to Modulate Desiccation Tolerance of Recalcitrant Cocoa and Ginkgo Embryonic Tissues1  

UK PubMed Central (United Kingdom)

Rate of dehydration greatly affects desiccation tolerance of recalcitrant seeds. This effect is presumably related to two different stress vectors: direct mechanical or physical stress because of the...Full Text Available

2002-04-01

266

Rapid Modulation of Spinach Leaf Nitrate Reductase by Photosynthesis 1  

UK PubMed Central (United Kingdom)

Assimilatory nitrate reductase activity (NRA) in crude spinach leaf (Spinacia oleracea) extracts undergoes rapid changes following fluctuations in photosynthesis brought about by changes...Full Text Available

1991-06-01

267

Range and modulation dependencies for proton beam dose per monitor unit calculations  

UK PubMed Central (United Kingdom)

Calculations of dose per monitor unit (D∕MU) are required in addition to measurements to increase patient safety in the clinical practice of proton radiotherapy. As in conventional photon and...Full Text Available

2009-02-01

268

PyEEG: An Open Source Python Module for EEG/MEG Feature Extraction  

UK PubMed Central (United Kingdom)

Computer-aided diagnosis of neural diseases from EEG signals (or other physiological signals that can be treated as time series, e.g., MEG) is an emerging field that has gained much attention in past...Full Text Available

2011-01-01

269

Prognostic gene network modules in breast cancer hold promise  

UK PubMed Central (United Kingdom)

A substantial proportion of lymph node-negative patients who receive adjuvant chemotherapy do not derive any benefit from this aggressive and potentially toxic treatment. However, standard histopathological...Full Text Available

2010-01-01

270

Priroda module docks with Mir station today - Johnson Space Center ...  

Science.gov (United States)

Apr 26, 1996 ... StainlesssteelJenn-Air cooktop w/4 burners, $20. Sam,332-3168. Sale:Condo, Friendswood,3-2-2A,1411sq It,. 409-925-4862. ...

271

Power system stabilizer system having improved integrity checking scheme  

Energy Technology Data Exchange (ETDEWEB)

This patent describes improvement in a system for stabilizing the operation of an electrical generator connected to a power distribution network of the type including a power system stabilizer for providing an oscillation signal having a value which normally represents generator oscillations and a modulator circuit responsive to input signals including the oscillation signal to provide a modulated output signal for varying generator excitation, means for checking for operational integrity of the power system stabilizer. It comprises: means for applying, to the power system stabilizer, a test signal of known amplitude and frequency, the test signal simulating generator oscillations and serving to produce a simulated oscillation signal for employment as the oscillation signal, means to store representations of time related values of the test signal; means to demodulate the modulated output signal to develop a demodulated ...

1991-03-12

272

Polymorphisms in the epidermal growth factor receptor gene and the risk of primary lung cancer: a case-control study  

UK PubMed Central (United Kingdom)

BackgroundPolymorphisms in Epidermal Growth Factor Receptor (EGFR) gene may influence EGFR production and/or activity, thereby modulating susceptibility to lung...Full Text Available

273

On the performances of Intensity Modulated Protons, RapidArc and Helical Tomotherapy for selected paediatric cases  

UK PubMed Central (United Kingdom)

BackgroundTo evaluate the performance of three different advanced treatment techniques on a group of complex paediatric cancer cases.MethodsCT...Full Text Available

274

Nonsteroidal Selective Androgen Receptor Modulators Enhance Female Sexual Motivation  

UK PubMed Central (United Kingdom)

Women experience a decline in estrogen and androgen levels after natural or surgically induced menopause, effects that are associated with a loss of sexual desire and bone mineral density. Studies in...Full Text Available

2010-08-01

275

Multiple Genes on Chromosome 7 Regulate Dopaminergic Amacrine Cell Number in the Mouse Retina  

UK PubMed Central (United Kingdom)

PurposeThe size of neuronal populations is modulated by gene variants that influence cell production and survival, in turn influencing neuronal connectivity, function,...Full Text Available

2009-05-01

276

Multilevel support vector regression analysis to identify condition-specific regulatory networks  

UK PubMed Central (United Kingdom)

Motivation: The identification of gene regulatory modules is an important yet challenging problem in computational biology. While many computational methods have been proposed to identify...Full Text Available

2010-06-01

277

Modulation of the human hair follicle pigmentary unit by corticotropin-releasing hormone and urocortin peptides  

UK PubMed Central (United Kingdom)

Human skin is a local source of corticotropin-releasing hormone (CRH) and expresses CRH and CRH receptors (CRH-R) at mRNA and protein levels. Epidermal melanocytes respond to CRH by induction...Full Text Available

2006-05-01

278

Modulation of leg muscle function in response to altered demand for body support and forward propulsion during walking  

UK PubMed Central (United Kingdom)

A number of studies have examined the functional roles of individual muscles during normal walking, but few studies have examined which are the primary muscles that respond to changes in external...Full Text Available

2009-05-11

279

Modulation of B-cell endoplasmic reticulum calcium homeostasis by Epstein-Barr virus Latent Membrane Protein-1  

UK PubMed Central (United Kingdom)

BackgroundCalcium signaling plays an important role in B lymphocyte survival and activation, and is critically dependent on the inositol-1,4,5-tris-phosphate-induced...Full Text Available

280

Modulation of Aire regulates the expression of tissue-restricted antigens  

UK PubMed Central (United Kingdom)

AbstractIntrathymic expression of tissue-restricted antigens (TRAs) has been viewed as the key element in the induction of central tolerance and recently, a central role for the autoimmune...Full Text Available

2008-01-01

281

Modulation of ASK1 expression during overexpression of Trx and HSP70 in stressed fish liver mitochondria  

UK PubMed Central (United Kingdom)

Mitochondrial heat shock protein 70 (mtHSP70) is found to play a primary role in cellular defense against physiological stress like exposure to environmental contaminants and helpful in the maintenance...Full Text Available

2009-09-01

282

Modular control of human walking: Adaptations to altered mechanical demands  

UK PubMed Central (United Kingdom)

Studies have shown that the nervous system may adopt a control scheme in which synergistic muscle groups are controlled by common excitation patters, or modules, to simplify the coordination...Full Text Available

2010-02-10

283

Membrane Efflux and Influx Modulate both Multidrug Resistance and Virulence of Klebsiella pneumoniae in a Caenorhabditis elegans Model?  

UK PubMed Central (United Kingdom)

Cross-resistance to cefoxitin (FOX), chloramphenicol (CMP), and quinolones (nalidixic acid [NAL]) related to a putative efflux system overexpression has recently been reported for Klebsiella...Full Text Available

2010-10-01

284

Mammalian target of rapamycin signaling modulates photic entrainment of the suprachiasmatic circadian clock  

UK PubMed Central (United Kingdom)

Inducible gene expression appears to be an essential event that couples light to entrainment of the master mammalian circadian clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus....Full Text Available

2010-05-05

285

Lipocalin 2 in the central nervous system host response to systemic lipopolysaccharide administration  

UK PubMed Central (United Kingdom)

BackgroundLipocalin 2 (Lcn2) is a bacteriostatic factor that may also modulate cellular function, however, little is known concerning the expression or role of Lcn2 in CNS inflammation....Full Text Available

286

Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor  

UK PubMed Central (United Kingdom)

Mammals possess multiple insulin-like growth factor (IGF) binding proteins (IGFBPs), and related proteins, that modulate the activity of insulin/IGF signalling (IIS), a conserved neuroendocrine signalling...Full Text Available

2011-02-01

287

Kinetic Complexity of the Global Response to Glucocorticoid Receptor Action  

UK PubMed Central (United Kingdom)

We have characterized the kinetic response of gene targets throughout the murine genome to transcriptional modulation by the glucocorticoid receptor (GR). In contrast to a model in which multiple genes...Full Text Available

2009-04-01

288

Intra- and extracellular calcium modulates stereocilia stiffness on chick cochlear hair cells.  

UK PubMed Central (United Kingdom)

Segments of the chick basilar papilla were isolated and maintained in culture medium. The sensory hair bundle of individual hair cells was observed with light microscopy and stimulated with a water...Full Text Available

1994-02-01

289

Integrative Analysis of Epigenetic Modulation in Melanoma Cell Response to Decitabine: Clinical Implications  

UK PubMed Central (United Kingdom)

Decitabine, an epigenetic modifier that reactivates genes otherwise suppressed by DNA promoter methylation, is effective for some, but not all cancer patients, especially those with solid tumors. It...Full Text Available

290

Infection of Dendritic Cells by a ?2-Herpesvirus Induces Functional Modulation1  

UK PubMed Central (United Kingdom)

The murine γ-herpesvirus-68 (γHV68) establishes viral latency in dendritic cells (DCs). In the present study, we examined the specific consequences...Full Text Available

2005-09-01

291

In-vivo coronary flow profiling based on biplane angiograms: influence of geometric simplifications on the three-dimensional reconstruction and wall shear stress calculation  

UK PubMed Central (United Kingdom)

BackgroundClinical studies suggest that local wall shear stress (WSS) patterns modulate the site and the progression of atherosclerotic lesions. Computational fluid dynamics (CFD)...Full Text Available

292

In Vivo Modulation of T-DNA Encoded Amidohydrolase Activity in Transformed Tobacco Cells 1  

UK PubMed Central (United Kingdom)

Auxin autonomous growth of most crown gall tumor cells requires the expression of two auxin biosynthesizing genes (tms 1 and tms 2) from the T-DNA of Agrobacterium...Full Text Available

1991-04-01

293

Identification of inhibitors of auxin transcriptional activation by means of chemical genetics in Arabidopsis  

UK PubMed Central (United Kingdom)

Auxin modulates diverse plant developmental pathways through direct transcriptional regulation and cooperative signaling with other plant hormones. Genetic and biochemical approaches have clarified...Full Text Available

2004-10-12

294

Huo-Luo-Xiao-Ling Dan modulates antigen-directed immune response in adjuvant-induced inflammation  

UK PubMed Central (United Kingdom)

Ethnopharmacological relevanceHLXL is a traditional Chinese medicine that has long been used in folk medicine for the treatment of chronic inflammatory diseases....Full Text Available

2009-05-04

295

Homeostasis of intrinsic excitability in hippocampal neurones: dynamics and mechanism of the response to chronic depolarization  

UK PubMed Central (United Kingdom)

In order to maintain stable functionality in the face of continually changing input, neurones in the CNS must dynamically modulate their electrical characteristics. It has been hypothesized that in...Full Text Available

2010-01-01

296

Head position modulates optokinetic nystagmus  

UK PubMed Central (United Kingdom)

Orientation and movement relies on both visual and vestibular information mapped in separate coordinate systems. Here, we examine how coordinate systems interact to guide eye movements of rabbits....Full Text Available

2011-08-01

297

Growth temperature reversibly modulates the virulence of Legionella pneumophila.  

UK PubMed Central (United Kingdom)

In chemostat culture, the virulence of two strains of Legionella pneumophila was shown to be significantly (P < 0.05) reduced when the culture temperature was lowered from 37 to 24 degrees C....Full Text Available

1994-07-01

298

Gravitropism: Interaction of Sensitivity Modulation and Effector Redistribution 1  

UK PubMed Central (United Kingdom)

Our increasing capabilities for quantitative hormone analysis and automated high resolution growth studies have allowed a reassessment of the classical Cholodny-Went hypothesis of gravitropism. According...Full Text Available

1991-01-01

299

Gonadal hormones modulate sex differences in judgments of relative numerousness in meadow voles, Microtus pennsylvanicus  

UK PubMed Central (United Kingdom)

Animals in a variety of taxa discriminate between a greater quantity and a lesser quantity of the same object, an ability that is referred to as relative numerousness judgment. For example,...Full Text Available

2009-01-01

300

Genetic Modulation of GABA Levels in the Anterior Cingulate Cortex by GAD1 and COMT  

UK PubMed Central (United Kingdom)

γ-Aminobutyric acid (GABA)-ergic transmission is critical for normal cortical function and is likely abnormal in a variety of neuropsychiatric disorders. We tested the in...Full Text Available

2010-07-01

301

Generalized support varieties for finite group schemes  

CERN Document Server

We construct two families of refinements of the (projectivized) support variety of a finite dimensional module $M$ for a finite group scheme $G$. For an arbitrary finite group scheme, we associate a family of {\\it non maximal rank varieties} $\\Gamma^j(G)_M$, $1\\leq j \\leq p-1$, to a $kG$-module $M$. For $G$ infinitesimal, we construct a finer family of locally closed subvarieties $V^{\\ul a}(G)_M$ of the variety of one parameter subgroups of $G$ for any partition $\\ul a$ of $\\dim M$. For an arbitrary finite group scheme $G$, a $kG$-module $M$ of constant rank, and a cohomology class $\\zeta$ in $\\HHH^1(G,M)$ we introduce the {\\it zero locus} $Z(\\zeta) \\subset \\Pi(G)$. We show that $Z(\\zeta)$ is a closed subvariety, and relate it to the non-maximal rank varieties. We also extend the construction of $Z(\\zeta)$ to an arbitrary extension class $\\zeta \\in \\Ext^n_G(M,N)$ whenever $M$ and $N$ are ...

2011-01-01

302

Functional significance of UDP-glucuronosyltransferase (UGT) variants in the metabolism of active tamoxifen metabolites  

UK PubMed Central (United Kingdom)

Tamoxifen (TAM) is a selective estrogen receptor modulator widely used in the prevention and treatment of breast cancer. A major mode of metabolism of the major active metabolites of TAM, 4-OH-TAM...Full Text Available

2009-03-01

303

Exercise Decreases Myelin-Associated Glycoprotein Expression in the Spinal Cord and Positively Modulates Neuronal Growth  

UK PubMed Central (United Kingdom)

To successfully grow, neurons need to overcome the effects of hostile environments, such as the inhibitory action of myelin. We have evaluated the potential of exercise to overcome the intrinsic...Full Text Available

2007-07-01

304

Engineering ligand-responsive RNA controllers in yeast through the assembly of RNase III tuning modules  

UK PubMed Central (United Kingdom)

The programming of cellular networks to achieve new biological functions depends on the development of genetic tools that link the presence of a molecular signal to gene-regulatory activity. Recently,...Full Text Available

2011-07-01

305

Emotional enhancement of memory: how norepinephrine enables synaptic plasticity  

UK PubMed Central (United Kingdom)

Changes in synaptic strength are believed to underlie learning and memory. We explore the idea that norepinephrine is an essential modulator of memory through its ability to regulate synaptic mechanisms....Full Text Available

306

Effects of removal of dietary polyunsaturated fatty acids on plasma extravasation and mechanical allodynia in a trigeminal neuropathic pain model  

UK PubMed Central (United Kingdom)

BackgroundNeuropathic pain (NP) is partially mediated by neuroinflammatory mechanisms, and also modulates local neurogenic inflammation. Dietary lipids, in particular the total amount...Full Text Available

307

EDISA: extracting biclusters from multiple time-series of gene expression profiles  

UK PubMed Central (United Kingdom)

BackgroundCells dynamically adapt their gene expression patterns in response to various stimuli. This response is orchestrated into a number of gene expression modules consisting...Full Text Available

308

Dose verification of helical tomotherapy intensity modulated radiation therapy planning using 2D-array ion chambers  

UK PubMed Central (United Kingdom)

Purpose:To investigate the clinical usage of dose verification of Helical Tomotherapy plans by using 2D-array ion chambers, and to develop an efficient way to validate the dose delivered...Full Text Available

309

Diagnosing mechanical changes: A test of the machine condition monitoring concept  

Energy Technology Data Exchange (ETDEWEB)

BC Hydro recently conducted a demonstration test of a bearing condition monitor. The test, at the 529-MW Kootenay Canal project, proved the ability of the monitor to detect machine condition faults. The capability to detect changing conditions during normal operation of hydroelectric machines gives hydro plant owners the opportunity to anticipate needed maintenance and ultimately to reduce the number of equipment failures. BC Hydro intends to install bearing condition monitors, as well as windings monitors, brushgear monitors, environmental monitors, and other selected systems in as many as 46 of its hydro generators. BC Hydro analyzed forced outages between 1985 and 1989 in its hydro system to identify which parts of a generating unit resulted in the highest number of hours of outage. From there, the utility has formulated a concept for a machine condition monitoring system. To keep the system cost effective, it will be developed in modules. In this way, users can ...

1993-05-01

310

Development of an Accelerated Weathering Protocol using Weatherometers for Reliability Study of Mini-Modules and Encapsulation Materials  

Energy Technology Data Exchange (ETDEWEB)

This paper describes the needs, reasoning, approaches, and technical details to establish a practical accelerated weathering test (AWT) protocol for indoor testing of the photothermal stability of encapsulation materials and encapsulated solar cells and minimodules.

2000-01-01

311

Development of a Selective Modulator of Aryl Hydrocarbon (Ah) Receptor Activity that Exhibits Anti-Inflammatory Properties  

UK PubMed Central (United Kingdom)

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. However, the role of the AHR...Full Text Available

2010-05-17

312

Detection of Streptococcus mutans Genomic DNA in Human DNA Samples Extracted from Saliva and Blood  

UK PubMed Central (United Kingdom)

Caries is a multifactorial disease, and studies aiming to unravel the factors modulating its etiology must consider all known predisposing factors. One major factor is bacterial colonization,...Full Text Available

2011-01-01

313

Current Role and Future Perspectives of Magnetic Resonance Spectroscopy in Radiation Oncology for Prostate Cancer  

UK PubMed Central (United Kingdom)

Prostatic neoplasms are not uniformly distributed within the prostate volume. With recent developments in three-dimensional intensity-modulated and imageguided radiation therapy, it is possible to treat...Full Text Available

2007-06-01

314

Construction of the ATLAS end cap electromagnetic calorimeter and study of its performances; Construction du bouchon du calorimetre electromagnetique d'ATLAS et etudes de ses performances  

Energy Technology Data Exchange (ETDEWEB)

ATLAS is one of the four experiments which will take place at the LHC, the CERN future protons collider. This accelerator, which should start in 2007, will allow to continue the studies carried out by its predecessors, as the standard model Higgs boson and new physics searches. The very high luminosity -10 fb{sup -1} during the first three functioning years, then 100 fb{sup -1}- and the 14 TeV in the frame center will ease these studies. The Centre de Physique des Particules de Marseille took part in the ATLAS collaboration, taking in charge half of the End-cap electromagnetic calorimeter modules construction. The description of this sub-detector and the construction steps, in particular the electrical tests which allow the stacking validation, are presented in this document. These tests results, obtained for the live first production modules, are analysed. The pre-series module (module 0) performances, ...

2002-09-01

315

Conjugated linoleic acid modulation of risk factors associated with atherosclerosis  

UK PubMed Central (United Kingdom)

Conjugated linoleic acid (CLA) has been the subject of extensive investigation regarding its possible benefits on a variety of human diseases. In some animal studies, CLA has been shown to have a beneficial...Full Text Available

316

Compressed-shell integrity measurements in spherical implosion experiments  

International Nuclear Information System (INIS)

The shell integrity near peak compression of spherical implosions using the 60-beam, 30-kJ UV OMEGA laser system [Opt. Commun. 133, 495 (1997)] has been measured. Hot core emission backlights a shell with a thin titanium-doped layer that is imaged at x-ray photon energies above and below the titanium K edge. The x-ray intensity ratio between the two images is related to perturbations in the cold, or absorbing, part of the shell. The measured cold-shell areal-density modulations, integrated over the time of peak compression, are of the order of 25% to 50% with nonuniformity spectra peaked at spatial wavelengths of 30 to 50 #mu#m and with the smallest detectable nonuniformity features extending down to spatial wavelengths of 12 to 15 #mu#m. Hot-shell areal-density modulations of the emitting part of the shell (inner edge) are of the order of 13% to 20%. The measured shell modulations are in agreement with the results of ...

2001-06-01

317

Comparative Structural Analysis of Lipid Binding START Domains  

UK PubMed Central (United Kingdom)

BackgroundSteroidogenic acute regulatory (StAR) protein related lipid transfer (START) domains are small globular modules that form a cavity where lipids and lipid hormones bind....Full Text Available

318

Colour television, an imitation of the human visual system.  

UK PubMed Central (United Kingdom)

Colour television is examined as an attempt to imitate the human visual system in image formation, spectral sensitivities, adaptation, contrast effects, signal processing, signal modulation, signal...Full Text Available

1975-07-01

319

Chromosome X modulates incidence of testicular germ cell tumors in Ter mice  

UK PubMed Central (United Kingdom)

Germ cell tumor development in humans has been proposed to be part of testicular dysgenesis syndrome (TDS), which manifests as undescended testes, sterility, hypospadias, and, in extreme cases,...Full Text Available

2007-12-01

320

Chemotherapy-induced alopecia in mice. Induction by cyclophosphamide, inhibition by cyclosporine A, and modulation by dexamethasone.  

UK PubMed Central (United Kingdom)

We introduce cyclophosphamide-induced alopecia (CYP-IA) in C57BL-6 mice as a clinically relevant model for studying the biology of chemotherapy-induced alopecia and for developing anti-alopecia drugs....Full Text Available

1994-04-01

321

Cerebrospinal fluid zinc concentrations in febrile convulsions.  

UK PubMed Central (United Kingdom)

Zinc modulates the activity of glutamic acid decarboxylase, the rate limiting enzyme in the synthesis of gamma-aminobutyric acid (GABA), which is a major inhibitory neurotransmitter. Low cerebrospinal...Full Text Available

1995-10-01

322

Castration and training in a spatial task alter the number of immature neurons in the hippocampus of male mice  

UK PubMed Central (United Kingdom)

New neurons are generated in the granule cell layer of the dentate gyrus (GCL) throughout adulthood. This process is modulated by many environmental and neurochemical factors. We previously...Full Text Available

2010-05-06

323

Camouflage by Artificial Foliage.  

Science.gov (United States)

A program was conducted to develop a pop-up artificial-foliage system compatible with the rural Maryland (summertime) background environment. The result of this Phase I effort was a self-expanding leaf module, a number of which are stored flat in a simple...

1974-01-01

324

Calcium Effects on Stomatal Movement in Commelina communis L. 1  

UK PubMed Central (United Kingdom)

Stomatal movements depend on both ion influx and efflux; attainment of steady state apertures reflects modulation of either or both processes. The role of Ca2+ in those two processes was...Full Text Available

1988-07-01

325

CRF receptors in the nucleus accumbens modulate partner preference in prairie voles  

UK PubMed Central (United Kingdom)

Recent evidence suggests a role for corticotropin-releasing factor (CRF) in the regulation of pair bonding in prairie voles. We have previously shown that monogamous and non-monogamous vole...Full Text Available

2007-04-01

326

Binary Pseudo-Random Gratings and Arrays for Calibration of Modulation Transfer Function of Surface Profilometers  

Energy Technology Data Exchange (ETDEWEB)

In the present work, we describe application of binary pseudo-random gratings (BPRG) and arrays (BPRA) as effective 1D and 2D test surfaces suitable for calibration of different surface profilometers, including a number of interferometric microscopes and scatterometers.

2009-06-17

327

Basic models and verification study on fuel rod heat-up and fission product release analysis modules in SAMPSON for the IMPACT project  

International Nuclear Information System (INIS)

The super simulator 'SAMPSON' has been developed to show that there exist certain safety margins for light water reactors under hypothetical severe accidents and to investigate realistic measures of accident management by simulating accidents with a parallel computer. Heat-up of fuel rods and release of fission products from fuels are important factors to evaluate source terms. Models for fuel rod heat-up, hydrogen production due to cladding oxidation and cladding deformation and failure in the core region have been developed in the fuel rod heat-up analysis module. Fuel temperatures were calculated by solving the heat conduction equation. The calculated results for fuel temperature and hydrogen production were compared with CORA-13 experiment results. The comparisons showed prediction capability for the heat-up of fuel rods. The fission product release analysis module incorporates with models for fission product transport within fuel pellets, ...

1999-04-19

328

Basic models and verification study on debris coolability analysis module in SAMPSON for IMPACT project  

Energy Technology Data Exchange (ETDEWEB)

Debris coolability in the lower plenum of the reactor pressure vessel is an important factor for evaluation of debris in-vessel retention. The debris coolability analysis module is developed for the accurate prediction of the safety margin of the present reactor vessels in a severe accident. The module calculates debris spreading and cooling through melting and solidification in combination with a temperature distribution and failure evaluation of the vessel wall. Debris spreading is solved by the explicit method on a quasi-three-dimensional scheme and debris coolability is solved on the basis of natural convection analysis. The calculation for spreading is compared with a water spreading experiment on the floor and the calculation for coolability is compared with a n-octadecane melting experiment in a rectangular vessel. The comparisons show capabilities for predictions of spearhead transportation in the debris spreading process and of melting ...

1999-07-01

329

Basic models and verification study on debris coolability analysis module in SAMPSON for IMPACT project  

International Nuclear Information System (INIS)

Debris coolability in the lower plenum of the reactor pressure vessel is an important factor for evaluation of debris in-vessel retention. The debris coolability analysis module is developed for the accurate prediction of the safety margin of the present reactor vessels in a severe accident. The module calculates debris spreading and cooling through melting and solidification in combination with a temperature distribution and failure evaluation of the vessel wall. Debris spreading is solved by the explicit method on a quasi-three-dimensional scheme and debris coolability is solved on the basis of natural convection analysis. The calculation for spreading is compared with a water spreading experiment on the floor and the calculation for coolability is compared with a n-octadecane melting experiment in a rectangular vessel. The comparisons show capabilities for predictions of spearhead transportation in the debris spreading process and of melting ...

1999-04-19

330

Average output lasing power of a He-Ne laser as a function of the modulation frequency of resonator losses  

Science.gov (United States)

The frequency dependence of the lasing power of a He-Ne laser was studied using the electrooptic effect in a KDP crystal. The gain profile of the power curve was found to differ noticeably between the high-frequency and low-frequency edges. (AIP). (AIP)

1976-09-01

331

Attenuation of Cocaine's Reinforcing and Discriminative Stimulus Effects via Muscarinic M1 Acetylcholine Receptor StimulationS?  

UK PubMed Central (United Kingdom)

Muscarinic cholinergic receptors modulate dopaminergic function in brain pathways thought to mediate cocaine's abuse-related effects. Here, we sought to confirm and ...Full Text Available

2010-01-01

332

Association of serum markers with improvement in clinical response measures after treatment with golimumab in patients with active rheumatoid arthritis despite receiving methotrexate: results from the GO-FORWARD study  

UK PubMed Central (United Kingdom)

IntroductionThe goal of this study was to identify serum markers that are modulated by treatment with golimumab with or without methotrexate (MTX) and are associated with clinical...Full Text Available

2010-01-01

333

Association Analysis of the Tryptophan Hydroxylase 2 Gene Polymorphisms in Patients with Methamphetamine Dependence/Psychosis  

UK PubMed Central (United Kingdom)

There is a growing evidence that serotoninergic systems modulate dopaminergic neurotransmission. We analyzed the association between the variations in the brain tryptophan hydroxylase 2 (TPH2)...Full Text Available

2011-03-01

334

Aspirin Treatment of Mice Infected with Trypanosoma cruzi and Implications for the Pathogenesis of Chagas Disease  

UK PubMed Central (United Kingdom)

Chagas disease, caused by infection with Trypanosoma cruzi, is an important cause of cardiovascular disease. It is increasingly clear that parasite-derived prostaglandins potently modulate...Full Text Available

335

Adrenaline modulates the global transcriptional profile of Salmonella revealing a role in the antimicrobial peptide and oxidative stress resistance responses  

UK PubMed Central (United Kingdom)

BackgroundThe successful interaction of bacterial pathogens with host tissues requires the sensing of specific chemical and physical cues. The human gut contains a huge number of...Full Text Available

336

Absence of Ataxin-3 Leads to Enhanced Stress Response in C. elegans  

UK PubMed Central (United Kingdom)

Ataxin-3, the protein involved in Machado-Joseph disease, is able to bind ubiquitylated substrates and act as a deubiquitylating enzyme in vitro, and it has been involved in the modulation of protein...Full Text Available

337

Ab binding alters gene expression in Cryptococcus neoformans and directly modulates fungal metabolism  

UK PubMed Central (United Kingdom)

Abs facilitate humoral immunity via the classical mechanisms of opsonization, complement activation, Ab-dependent cellular cytotoxicity, and toxin/viral neutralization. There is also evidence that some...Full Text Available

2010-04-01

338

A randomized-controlled trial of low-dose doxycycline for periodontitis in smokers  

UK PubMed Central (United Kingdom)

Background/AimTobacco use reduces the effect of non-surgical periodontal therapy. Host-modulation with low-dose doxycycline (LDD) might favour repair and promote...Full Text Available

2007-04-01

339

A frequency-based approach to locate common structure for 2D-3D intensity-based registration of setup images in prostate radiotherapy  

UK PubMed Central (United Kingdom)

In many radiotherapy clinics, geometric uncertainties in the delivery of 3D conformal radiation therapy and intensity modulated radiation therapy of the prostate are reduced by aligning the...Full Text Available

2007-07-01

340

A conserved switch in sensory processing prepares developing neocortex for vision  

UK PubMed Central (United Kingdom)

Developing cortex generates endogenous activity that modulates the formation of functional units, but how this activity is altered to support mature function is poorly understood. Using recordings...Full Text Available

2010-08-12

341

A Cellular J-Domain Protein Modulates Polyprotein Processing and Cytopathogenicity of a Pestivirus  

UK PubMed Central (United Kingdom)

Pestiviruses are positive-strand RNA viruses closely related to human hepatitis C virus. Gene expression of these viruses occurs via translation of a polyprotein, which is further processed by cellular...Full Text Available

2001-10-01

342

Results of thermal performance evaluation of the Owens-Illinois Sunpak liquid solar collector at indoor conditions  

Science.gov (United States)

This report provides test results on the thermal performance of an Owens-Illinois Sunpak liquid, evacuated tube, solar collector under simulated conditions. The test was conducted using the Marshall Space Flight Center Solar Simulator in accordance with the test requirements specified in ASHRAE 93-77 (Method of Testing to Determine the Thermal Performance of Solar Collectors) and the procedures contained in MTCP-FA-SHAC-400 (Procedure for Operation of the MSFC Solar Simulator Facility). The tests were performed on a module used on the early demonstration projects. A current production module is undergoing tests with results to be in a subsequent report.

1979-10-10

343

Plasma Dynamics in the Vicinity of the Local Plasma resonance Point Excited by Pumping Electric Field or Modulated Electron Beam  

International Nuclear Information System (INIS)

Excitation of the HF electric field in the local plasma resonance region (LPRR) of inhomogeneous plasma by pumping electric field or modulated electron beam results to appearance of the ponderomotive force that presses plasma out of this region. Density cavity is formed in the LPRR due to this field. Further dynamics in this region depends on the plasma properties. For plasma with hot electrons ion-acoustic pulses run away from the cavity. at the local density maximum the new peak of electric field is excited. It results to the formation of new density cavity, etc. For isothermal plasma the density jump is formed.

2006-01-01

344

Observation of stochastic resonance near a subcritical bifurcation  

Energy Technology Data Exchange (ETDEWEB)

A hysteretic subcritical period-doubling bifurcation is observed in the nonlinear strain dynamics of a magnetostrictive oscillator. The dynamic strain response of the magnetostrictive oscillator was observed with a high-resolution fiber optic interferometer. The effects of low-frequency modulation and band-limited stochastic fluctuations on such a bifurcation are investigated. Power spectral density measurements show that for an optimal value of externally injected noise the signal-to-noise ratio of a low-frequency modulation signal is enhanced by greater than 14 dB, thus indicating the first experimental observation of stochastic resonance near a bistable period-doubling bifurcation. 10 refs., 7 figs.

1993-01-01

345

Nuclear data activity at Atomic Energy Research Establishment, Savar, Dhaka  

Energy Technology Data Exchange (ETDEWEB)

The nuclear data activity at AERE, Savar is briefly presented in this paper. Major thrust is on the customization of cross section libraries for general purpose reactor and shielding calculations. The processing codes that are available are NJOY91.91, some AMPX-Modules and the modules in SCALE-PC. Recent measurements on cross section data over the energy range 13-15 MeV at the Institute of Nuclear science and Technology have been reviewed. Measurements and calculations are based on the determination of excitation functions of neutron induced reactions on the elements and isotopes of FRT-relevant structural materials. (author).

1995-03-01

346

New low pressure exhaust modules for the MAN steam turbine product line. High performance bladings for highest efficiency levels; Neue Niederdruck-Module fuer die MAN-Dampfturbinenproduktlinie. Hochentwickelte Beschaufelungen fuer hoechste Leistungsdichten und Wirkungsgrade  

Energy Technology Data Exchange (ETDEWEB)

Currently it can be observed that in the case of generator drives as well as 'mechanical drives' smaller units are demanded with a steam turbine capacity of up to 150 MW and clearly higher efficiencies. MAN TURBO is meeting the challenge through realisation of a comprehensive development project aiming at the extension of the application range of the current steam turbine series.

2008-07-01

347

Final design and manufacturing of the Cryolegs of the W7-X-superconducting coil support system  

Energy Technology Data Exchange (ETDEWEB)

One of the most complicated tasks during the assembly of the Wendelstein W7-X is the installation of the superconductive coil system. The entire magnet system is enclosed between the Outer Vessel and the plasma vessel in high vacuum at 4 K. The coils are supported by a support structure, the Central Support Structure (CSS). The CSS carries all 70 coils, and it is designed as a closed ring made of 5 modules (10 half modules). The whole structure is supported by 10 Cryolegs which rest on the machine base. This paper describes the final design and manufacture of these Cryolegs.

2008-12-15

348

Experimental generation of non-Kolmogorov turbulence using a liquid crystal spatial light modulator  

Science.gov (United States)

Several experiments showed that the classical Kolmogorov power spectral density of the refractive-index sometimes does not properly describe the statistics of the atmosphere. In this paper we show an experimental testbed able to generate non-classical Kolmogorov turbulence by using a liquid crystal spatial light modulator. The testbed is used at Naval Postgraduate School for laboratory investigation of laser beam propagation in maritime environment where a power law different from classical Kolmogorov, 11/ 3, could be present. Applications of this testbed are ship to-ship free space optical communication, imaging and high energy laser weapons.

2011-09-01

349

Development of the EE-1 small community solar thermal power system  

Science.gov (United States)

The development status of the EE-1 Small Community Solar Thermal Power Experiment (SCSE Program) is presented. Current activities on the Phase II single module development effort are presented, together with plans for a Phase III 1 MW/sub e/ demonstration plant. A description of the various subsystems and components is given with a brief review of their development background. Latest performance figures are given for a 1 MW/sub e/ plant, based on 56 power modules, each consisting of a 12m parabolic dish concentrator, a cavity receiver, an organic Rankine power conversion subsystem and a ground-mounted solid-state rectifier.

1981-01-01

350

Coherent state quantum key distribution with multi letter phase-shift keying  

International Nuclear Information System (INIS)

We present a protocol for quantum key distribution using discrete modulation of coherent states of light. Information is encoded in the variable phase of coherent states which can be chosen from a regular discrete set ranging from binary to continuous modulation similar to phase-shift keying in classical communication. Information is decoded by simultaneous homodyne measurement of both quadratures and requires no active choice of basis. The protocol utilizes either direct or reverse reconciliation both with and without postselection. We analyze the security of the protocol and show how to enhance it by the optimal choice of all variable parameters of the quantum signal.

2010-05-01

351

Bases for the derivation modules of two-dimensional multi-Coxeter arrangements and universal derivations  

CERN Document Server

Let $\\A$ be an irreducible Coxeter arrangement and $\\bfk$ be a multiplicity of $\\A$. We study the derivation module $D(\\A, \\bfk)$. Any two-dimensional irreducible Coxeter arrangement with even number of lines is decomposed into two orbits under the action of the Coxeter group. In this paper, we will {explicitly} construct a basis for $D(\\A, \\bfk)$ assuming $\\bfk$ is constant on each orbit. Consequently we will determine the exponents of $(\\A, \\bfk)$ under this assumption. For this purpose we develop a theory of universal derivations and introduce a map to deal with our exceptional cases.

2010-01-01

352

An energy management teaching module for management education in the Higher Vocational Education schools in the Netherlands. Lesmodule energiebeheer voor managementgericht onderwijs in het Hoger Beroepsonderwijs; Fase 1: Market research (Final report)  

Energy Technology Data Exchange (ETDEWEB)

The demand for energy management in teaching packages of Higher Vocational schools in the Netherlands and the possibilities to implement energy management into the different sectors of this school type have been investigated. The results are based on interviews with representative of the above-mentioned school types. Recommendations are made for a follow-up of this investigation in order to set up an energy management teaching module. 1 tab., 1 appendix

1992-02-01

353

2D Electrostatic Simulation of the Modulated Electron Beam Interaction with Inhomogeneous Plasma  

International Nuclear Information System (INIS)

Electrostatic plasma simulation code for 2D rectangular geometry is presented. Main distinguishing feature of the code is its orientation on the beam-plasma interaction. The code and its graphical interface were developed using MATLAB programming language. Simulation results of inhomogeneous plasma interaction with modulated electron beams of different width are compared. In case of wide beam the front of Langmuir waves generated in point of local plasma resonance is planar and in case of thin beam (or ribbon beam) the front has approximately half-circular form.

2006-01-01

354

The feasibility study of hot cell decontamination by the PFC spray method  

International Nuclear Information System (INIS)

The characteristics of per-fluorocarbon compounds (PFC) are colorless, non-toxic, easily vaporized and nonflammable. Also, some of them are liquids of a high density, low surface tension, low latent heat and low specific heat. These particular chemical and physical properties of fluoro-organic compounds permit their use in very different fields such as electronics, medicine, tribology, nuclear and material science. The Sonatol process was developed under a contract with the DOE. The Sonatol process uses an ultrasonic agitation in a PFC solution that contains a fluorinated surfactant to remove radioactive particles from surfaces. Filtering the suspended particles allows the solutions to be reused indefinitely. They applied the Sonatol process to the decontamination of a heterogeneous legacy Pu-238 waste that exhibited an excessive hydrogen gas generation, which prevents a transportation of such a waste to a Waste Isolation Pilot Plant. Korea Atomic Energy Research Institute (KAERI) is ...

2008-01-01

355

Pulse power considerations for the generation of 45 #mu#s, 200 keV electron beams for CO_2 lasers  

International Nuclear Information System (INIS)

A two module electron beam source operating over a wide range of output parameters has been designed and fabricated to be used in conjunction with a pair of electron beam sustained CO_2 lasers. Each module comprised a grid-controlled thermionic electron beam gun including a compact grid pulser for control of the electron beam, a 250 kV thyratron switched modulator for acceleration of the electron beam, a 1 kHz filament heater and a complex computerized control system. The system was designed to reliably produce 45 #mu#s wide electron pulses of 150-200 keV energy, operate at repetition rates of 1-10 pps and current densities of 5-20 mA/cm"2. Additional parameters are listed. The high voltage cathode assembly employs 132 thoriated tungsten filaments distributed over the area of the 250 cm x 10 cm output window. The cathode assembly including the control grids is supported by two high voltage ceramic bushings in a stainless ...

1989-01-19

356

A simple 5-DoF MR-compatible motion signal measurement system.  

Science.gov (United States)

The purpose of this study was to develop a simple motion measurement system with magnetic resonance (MR) compatibility and safety. The motion measurement system proposed here can measure 5-DoF motion signals without deteriorating the MR images, and it has no effect on the intense and homogeneous main magnetic field, the temporal-gradient magnetic field (which varies rapidly with time), the transceiver radio frequency (RF) coil, and the RF pulse during MR data acquisition. A three-axis accelerometer and a two-axis gyroscope were used to measure 5-DoF motion signals, and Velcro was used to attach a sensor module to a finger or wrist. To minimize the interference between the MR imaging system and the motion measurement system, nonmagnetic materials were used for all electric circuit components in an MR shield room. To remove the effect of RF pulse, an amplifier, modulation circuit, and power supply were located in a shielded case, which was made ...

2011-09-01

357

A 3-D hydrodynamic dispersion model for modeling tracer transport in Geothermal Reservoirs  

International Nuclear Information System (INIS)

A 3-D hydrodynamic dispersion model for tracer transport is developed and implemented into the TOUGH2 EOS3 (T2R3D) module. The model formulation incorporates a full dispersion tensor, based on a 3-D velocity field with a 3-D, irregular grid in a heterogeneous geological system. Two different weighting schemes are proposed for spatial average of 3-D velocity fields and concentration gradients to evaluate the mass flux by dispersion and diffusion of a tracer or a radionuclide. This new module of the TOUGH2 code is designed to simulate processes of tracer/radionuclide transport using an irregular, 3-D integral finite difference grid in non-isothermal, three-dimensional, multiphase, porous/fractured subsurface systems. The numerical method for this transport module is based on the integral finite difference scheme, as in the TOUGH2 code. The major assumptions of the tracer transport module are: (a) a tracer ...

358

Thermokinetic investigation of effects of carbon source on petroleum bacterial growth  

Energy Technology Data Exchange (ETDEWEB)

The growth power-time curves of a strain of petroleum bacteria, B-2, in various kinds of cultures containing different kinds of carbon sources, glucose, n-tetradecane, n-hexadecane and n-octadecane, and different kinds of microemulsions have been determined by using a 2277 Thermal Activity Monitor. The curves showed a single peak for cultures containing a single carbon source, glucose, and two peaks for cultures containing two kinds of carbon sources, glucose and one of the n-alkanes. The first peak indicated that bacteria grew by consuming glucose and the second peak indicated that bacteria grew by consuming n-alkane. The curves were complex when the bacterium grows in a microemulsion culture. According to a kinetic equation of bacterial growth under limited conditions, the rate constants of bacterial growth were obtained. The results showed that the microemulsion culture was more appropriate to bacteria to grow on n-alkanes.

2002-02-07

359

The deformation behavior of DyCu ductile intermetallic compound under compression  

British Library Electronic Table of Contents (United Kingdom)

In this study polycrystalline specimens of as-cast DyCu with B2 crystal structure were compressed to different strains at room temperature to test if stress-induced phase transformation and twinning occur during deformation. In these tests DyCu exhibited high ductility with plastic strain as high as 35% and ultimate compressive strength of ~790MPa. X-ray diffraction and transmission electron microscopy (TEM) showed no indications that DyCu had undergone stress-induced phase transformation or twinning. -type dislocations have been observed to play an important role for imparting the ductile behavior. TEM analyses showed the presence of second phases, Dy2O3 and DyCu2 within the DyCu. The mechanisms of ductility and impurity phase formation are discussed.

2011-01-01

360

Texture transformations in thermomechanically treated steels having increased nitrogen content and alloys  

International Nuclear Information System (INIS)

In this study the results of mathematical simulation and experimental research of texture transition in stress assisted shear phase transformations are discussed. The orientation distribution function (ODF) calculation model to the any type crystalline lattice symmetry materials has been suggested. By crystalline lattice symmetry analysis this computer program determines necessary amount of the initial experimental data. The experimental verification supports this model well. The ODF calculation model after shear phase transformation with equal use of all possible variants of orientation relationship or with various degrees of variant selection worked out. In this study the experimental and calculating data of the direct and reversal shear transformations #alpha# <=> #gamma# in Fe-alloys and B2 <=> B19' in Ti-Ni alloys are discussed. The stress assisted shear phase transformation model and computer program to calculate ODF after ...

361

Porous b2;-SiAlON Ceramic with Closed Packed Macropore  

British Library Electronic Table of Contents (United Kingdom)

Porous ?-SiAlON ceramics are synthesized by reaction bonded method using hollow alumina spheres (HASs) as both sintering aids and pore-forming agents. Both micropores and macropores, which are constructured by SiAlON grains with different morphologies, are formed in the final SiAlON samples. The micropores are three-dimentional, and are built by equiaxial grains. While the hollow macropores, which have the similar morphology to hollow alumina sphere, are packed by elongated grains. In the sintering process, the solid dissolution process takes place, giving rise to the different alumina concentration of liquid phase, and thus resulting in the formation of two kinds of grains, the equiaxial grain and the elongated grain.

2011-01-01

362

Point-contact Andreev spectroscopy on thin Ni_2MnIn Heusler films  

International Nuclear Information System (INIS)

Heusler films with L2_1 and B2 structure are deposited simultaneously on amorphous carbon films, Si(100) surfaces, and in situ cleaved InAs(110) surfaces by coevaporation of Ni and the alloy MnIn. Morphology, structure, and stoichiometry are investigated with transmission-electron microscopy, electron diffraction, and X-ray spectroscopy. The almost perfect lattice match supports highly oriented growth of Ni_2MnIn on InAs, which is proven by electron diffraction under grazing incidence. The electrical resistivity of thin films on Si show metallic behavior. At temperatures of liquid helium point-contact Andreev reflection spectroscopy is performed on films grown on Si(100) and in situ cleaved InAs(110) surfaces yielding spin polarizations comparable to the ones of Fe, Ni, Co, and permalloy (Ni_8_0Fe_2_0).

2007-09-01

363

Phase stability, electronic and elastic properties of ScN  

International Nuclear Information System (INIS)

The structural stability, electronic and elastic properties of ScN under high pressure were investigated by using full-potential linearized augmented plane-wave (FP-LAPW) method. Our calculations indicate that there exists a pressure-induced structural phase transformation from the ambient rock-salt (B1) phase to CsCl-type (B2) phase above 335 GPa. The origin of moderate high bulk modulus, mechanical and high melting point was analyzed by electronic properties. The variations of elastic constants (C_i_j) with volume and pressure have been investigated. Moreover, the volume dependencies of Debye temperature, the longitudinal and transverse elastic wave velocities have been presented.

2010-06-01

364

Online consumer communities, collaborative learning and innovation  

British Library Electronic Table of Contents (United Kingdom)

Purpose - The paper aims to outline the managerial challenges faced by the organizations interested in leveraging knowledge and creative talent embedded in online customers' communities to sustain innovation in b-2-c industries. Design/methodology/approach - Through a detailed case study analysis of a leading food producer who launched an online open collaborative platform to gather users' idea for new products the paper aims to highlight the transformational effort that firms have to make in order to leverage knowledge absorption from customers in the context of innovation. Findings - The paper suggests potential strategies for conventional companies to engage consumers in knowledge (co-creation) and collaborative innovation processes, formulating some hypothesis that could support an int...

2011-01-01

365

Oak Ridge Research Reactor. Quarterly report, July, August, and September 1984  

Energy Technology Data Exchange (ETDEWEB)

The ORR operated at an average power level of 29.7 MW for 85.3% of the time during this period. The reactor was shut down on fifteen occasions, nine of which were unscheduled. Reactor downtime needed for refueling and checks was normal. The reactor remained available for operation 88.3% of the time. Special tests completed during the quarter included: (1) transfer of LEU fuel elements CLE-202 and NLE-201 from core positions B-9 and B-2 to core positions C-5 and C-6 for continued operation; and (2) calculation of maximum heat flux in LEU elements CLE-201 and NLE-202 in core positions A-2 and A-8. In-service inspections included inspections of ORR decay tank, primary heat exchanger No. 4, and the 24-in. strainer.

1985-03-01

366

Moessbauer investigation of the magnetic anisotropy and electronic structure of a metallic glass  

International Nuclear Information System (INIS)

The temperature dependence of the average magnetization direction in an Fe_8_0B_2_0 glassy alloy (METGLAS 2605) is investigated by Moessbauer spectroscopy. Moessbauer spectra were recorded between 77 K and 363 K using a conventional constant-acceleration Moessbauer spectrometer with 10 mCi "5"7Co in Pd source. The direction of the easy magnetization is found to be strongly terperature dependent and the out-of-plane component turned to be unusually large. Comparing the magnetic moments some similarities between the electronic structure of the glassy alloy and the Fe_2B and FeB intermetallic compounds are established and discussed. (Sz.N.Z.).

367

Microstructure characterization and tensile properties of b phase containing TiAl pancake  

British Library Electronic Table of Contents (United Kingdom)

The microstructure and tensile properties of Ti-44Al-6V-3Nb-0.3Y (at.%) alloy after canned forging were investigated. SEM results showed that the TiAl pancake exhibits inhomogeneous microstructure, which can be ascribed to the temperature drop and friction between billet and outer pack during forging, as well as the intrinsic anisotropy of lamellar colony. By means of TEM observation and EBSD analysis, the microstructure in the dominant area of the pancake was further characterized. This deformation area consists of 87.7% content of g grains plus some refined lamellar colonies and the rest of B2 grains. The grain size ranges between 1mm and 8.5mm. High-angle boundaries dominate the deformation microstructure, several substructures and twins are observed as well. Additionally, current forge...

2011-01-01

368

Mechanisms of Reproductive Thermotolerance in Gossypium hirsutum: The Effect of Genotype and Exogenous Calcium Application  

British Library Electronic Table of Contents (United Kingdom)

Abstract Although photosynthetic thermotolerance has been investigated extensively in cotton leaves, reports on the biochemical influence of the pistil in promoting fertilization thermostability are limited. To evaluate the effect of temperature, genotype, and exogenous calcium application on fertilization and pistil biochemistry in cotton, thermosensitive (cv. ST4554 B2RF) and thermotolerant (cv. VH260) plants were grown under control (30/20-C) or high-temperature (38/20-C) conditions during flowering, and exogenous CaCl2 was applied to flowers 1-day prior to anthesis. Measured pistil parameters included fertilization efficiency; protein concentration; glutathione reductase, superoxide dismutase (SOD) and NADPH oxidase activities; and ATP and calcium levels. Exogenous calcium had no effec...

2011-01-01

369

Interaction studies between Crofer-22APU alloy and P2O5 containing barium calcium alumino-borosilicate (BCABS) sealant glass-ceramics  

International Nuclear Information System (INIS)

We present the effect of P2O5 addition on barium calcium aluminum borosilicate BCABS glasses of composition (mol %) 35BaO-15CaO-5Al2O3-(37-x)SiO2-8B2O3-xP2O5 (0?x?5). The incorporation of P2O5 increased network polymerization and crystallization tendency. However, addition of P2O5 leads to the formation of Cr2O3 at the interface, saturating it in the ions of the metal. This improves glass-to-metal bonding. (author)

2010-09-01

370

Hydrogen lines in the high-luminosity quasar B2 1225+31  

International Nuclear Information System (INIS)

The emission lines H#alpha#, H#beta#+[OIII], and L#alpha# have been observed in the high-redshift quasar 1225+31. The ratios of line intensities in 1225+31 are found to be L#alpha#/H#alpha#approx.0.8, H#alpha#/(H#beta#+[OIII]) approx.4, and 4

371

G-factor of the 21/2/sup +/ isomer in /sup 203/Pb  

Energy Technology Data Exchange (ETDEWEB)

The g-factor of the 21/2/sup +/ state at 1921.9 keV in /sup 203/Pb has been measured through the time differential perturbed angular distribution technique in an external magnetic field B=2.028 T. The measured g-factor g=-0.063(2) indicates a predominantly three neutron hole configuration described by the wave function 0.68vertical strokei/sup -1//sub 13/2/f/sup -2//sub 5/2/>+-0.73vertical strokei/sup -1//sub 13/2/f/sup -1//sub 5/2/p/sup -1//sub 3/2/>.

1986-12-01

372

Feasibility investigations of growing and characterizing gallium arsenide crystals in ribbon form. Quarterly progress report 1 Jan-31 Mar 1975  

International Nuclear Information System (INIS)

The feasibility of continuous production of gallium arsenide ribbon single crystals, by passage of a molten zone through boron-oxide encapsulated GaAs feedstock, is being investigated. Polycrystalline GaAs ribbons have been grown in graphite boats by passage of a wide zone through B2O3-encapsulated feed-stock, confined by a quartz cover plate. Failure to remove the encapsulant above its glass transition temperature, however, resulted in cracking of the ribbons on cooling to room temperature. In order to study the crucial zone melting step in isolation from the encapsulation steps of the continuous process, a constrained-zone melting apparatus has been constructed in which the boron oxide serves only as a sealant to suppress arsenic vaporization. Large grained polycrystalline samples have been produced with this apparatus.

373

Effect of alloying on the phase transformations and properties of a nickel alloy  

Energy Technology Data Exchange (ETDEWEB)

The phase transformations and properties of a precipitation-hardened Ni-Cr-based alloy are investigated as a function of C, B, Nb, and Cr contents. It is found that the primary role of Nb consists in the formation of an independent phase, delta-Ni3Nb, a part of a gamma/gamma-prime-delta eutectoid (for high C and B concentrations) and in stimulating the gamma-sigma reaction consecutively with the gamma double prime-delta reaction (for low C and B concentrations). In both cases, the long-term strength characteristics of the Nb-alloyed system are relatively low. The substitution of boron for carbon contributes to a reduction in the number of nucleation sites for topologically close-packed phases and to the formation of more stable (with respect to excess compounds) M3B2 and MB2 borides. The high-boron material exhibits better properties and phase stability under mechanical and thermal loading. 13 references.

1986-07-01

374

Development of Point Arguello field, offshore California  

Energy Technology Data Exchange (ETDEWEB)

Development drilling from Chevron-operated Platform Hermosa, located on OCS-P 0316 of the Point Arguello field, began on January 30, 1987. To date, seven development wells have been drilled in to the northwest-southeast-trending, doubly plunging anticlinal structure. The results from drilling have confirmed the presence of intense folding and fracturing in the targeted Monterey Formation. Over 700 ft of conventional core were recovered from the B-2 well in the lower Sisquoc and Monterey Formations. Analysis of the core material has yielded important information on lithologic variations and fracture patterns in the productive Monterey Formation. Initial results of core studies, DST data, and wireline studies indicate a correlation between rock type and fracturing. Fracture trends and directional permeability suggested by drill-stem testing may affect future drilling patterns in the field.

1988-03-01

375

Combining climate with other influential factors for modelling the impact of climate change on species distribution  

British Library Electronic Table of Contents (United Kingdom)

We tested two approaches to forecast species distributions while balancing the impact of climate change against the inertia promoted by other influential factors that have been forecast as not changing. Given that mountain species are presumed to be more at risk due to climate warming, we selected an amphibian, a reptile, a bird, and a mammal species present in the Spanish mountains, to model their distributional response to climate change during this century. The climatic forecasts were made according to the general circulation models CGCM2 and ECHAM4 and to the A2 and B2 emission scenarios. We modelled the response of the species to spatial, topographic, human, and climatic variables separately. In our first approach, we compared each of these single-factor models using the Akaike Inform...

2011-01-01

376

Catalytic effect of oxides and sulfides of metallic minerals on hydrogenation of Kansk-Achinsk brown coal  

Energy Technology Data Exchange (ETDEWEB)

Discusses results of investigations into catalytic properties of various minerals during hydrogenation of Kansk-Achinsk brown coal with a view to replacing synthetic compositions based on molybdenum. Describes tests and equipment used in hydrogenation of grade B-2 Borodinsk deposit coal in tetralin (hydrogen donor). Various by-products of metallurgical processes and compounds separated from tailings containing mainly iron and sulfur and other metals were used as catalysts. States that: minerals containing iron compounds in the form of pyrites, hematites and magnetites exhibit catalytic properties when used in the hydrogenation of brown coal; pyritic catalysts enrich liquid products with hydrogen while sulfur and nitrogen content remains the same; the yield of malthenes with pyritic catalysts is no lower than with alumocobaltmolybdenum catalysts. 18 refs.

1988-05-01

377

A strategy for implementing non-perturbative renormalisation of heavy-light four-quark operators in the static approximation  

Energy Technology Data Exchange (ETDEWEB)

We discuss the renormalisation properties of the complete set of {delta}B=2 four-quark operators with the heavy quark treated in the static approximation. We elucidate the role of heavy quark symmetry and other symmetry transformations in constraining their mixing under renormalisation. By employing the Schroedinger functional, a set of non-perturbative renormalisation conditions can be defined in terms of suitable correlation functions. As a first step in a fully non-perturbative determination of the scale-dependent renormalisation factors, we evaluate these conditions in lattice perturbation theory at one loop. Thereby we verify the expected mixing patterns and determine the anomalous dimensions of the operators at NLO in the Schroedinger functional scheme. Finally, by employing twisted-mass QCD it is shown how finite subtractions arising from explicit chiral symmetry breaking can be avoided completely. (Orig.)

2006-04-15

378

Transmission electron microscope characterization of AlGaInP grown by organometallic vapor phase epitaxy  

Energy Technology Data Exchange (ETDEWEB)

AlGaInP epitaxial layers grown at 690 {degree}C by atmospheric pressure organometallic vapor phase epitaxy are investigated by transmission electron microscopy. For the first time, compositionally modulated and ordered structures are simultaneously observed in AlGaInP alloys. The ordering is of the CuPt type with ordering along the {l brace}111{r brace} directions. The ordered regions appear as plate-like microdomains, while the composition modulation takes the form of a fine columnar constrast oriented along the growth direction. In addition, from the results of (001) plan-view diffraction contrast examination, the principal strain direction associated with the modulation structures is found to be perpendicular to the growth direction and lies in the surface plane. Thus, it is concluded that the spinodal decomposition is initiated and developed on the surface during the growth of the AlGaInP epitaxial layers and, finally, ...

1990-04-09

379

Transmission electron microscope characterization of AlGaInP grown by organometallic vapor phase epitaxy  

International Nuclear Information System (INIS)

AlGaInP epitaxial layers grown at 690 degree C by atmospheric pressure organometallic vapor phase epitaxy are investigated by transmission electron microscopy. For the first time, compositionally modulated and ordered structures are simultaneously observed in AlGaInP alloys. The ordering is of the CuPt type with ordering along the #left brace#111#right brace# directions. The ordered regions appear as plate-like microdomains, while the composition modulation takes the form of a fine columnar constrast oriented along the growth direction. In addition, from the results of (001) plan-view diffraction contrast examination, the principal strain direction associated with the modulation structures is found to be perpendicular to the growth direction and lies in the surface plane. Thus, it is concluded that the spinodal decomposition is initiated and developed on the surface during the growth of the AlGaInP epitaxial layers and, ...

380

Solar-powered unmanned aerial vehicles  

Energy Technology Data Exchange (ETDEWEB)

An analysis was performed to determine the impact of various power system components and mission requirements on the size of solar-powered high altitude long endurance (HALE)-type aircraft. The HALE unmanned aerial vehicle (UAV) has good potential for use in many military and civil applications. The primary power system components considered in this study were photovoltaic (PV) modules for power generation and regenerative fuel cells for energy storage. The impact of relevant component performance on UAV size and capability were considered; including PV module efficiency and mass, power electronics efficiency, and fuel cell specific energy. Mission parameters such as time of year, flight altitude, flight latitude, and payload mass and power were also varied to determine impact on UAV size. The aircraft analysis method used determines the required aircraft wing aspect ratio, wing area, and total mass based on maximum endurance or minimum ...

1996-12-31

381

Mixed waste solidification testing on polymer and cement-based waste forms in support of Hanford`s WRAP 2A facility  

Energy Technology Data Exchange (ETDEWEB)

A testing program has been conducted by the Westinghouse Hanford Company to confirm the baseline waste form selection for use in Waste Receiving and Processing (WRAP) Module 2A. WRAP Module 2A will provide treatment required to properly dispose of containerized contact-handled, mixed low-level waste at the US Department of Energy Hanford Site in south-central Washington State. Solidification/stabilization has been chosen as the appropriate treatment for this waste. This work is intended to test cement-based, thermosetting polymer, and thermoplastic polymer solidification media to substantiate the technology approach for WRAP Module 2A. Screening tests were performed using the major chemical constituent of each waste type to measure the gross compatibility with the immobilization media and to determine formulations for more detailed testing. Surrogate materials representing each of the eight waste types were prepared in the ...

1993-10-01

382

Low concentration ratio solar array for low Earth orbit multi-100kW application. Volume 2: Drawings. Final Report  

Energy Technology Data Exchange (ETDEWEB)

A preliminary design effort directed toward a low concentration ratio photovoltaic array system based on 1984 technology and capable of delivering multi-hundred kilowatts (300 kW to 100 kW range) in low Earth orbit is described. The array system consists of two or more array modules each capable of delivering between 113 kW to 175 kW using silicon solar cells or gallium arsenide solar cells, respectively. The array module deployed area is 1320 square meters and consists of 4356 pyramidal concentrator elements. The module, when stowed in the Space Shuttle's payload bay, has a stowage volume of a cube with 3.24 meters on a side. The concentrator elements are sized for a geometric concentration ratio (GCR) of six with an aperture area of 0.5 meters x 0.5 meters. Drawings for the preliminary design configuration and for the test hardware that was fabricated for design evaluation and test are provided.

1982-07-01

383

Low concentration ratio solar array for low Earth orbit multi-100 kW application. Volume 1: Design, analysis and development tests. Final Report  

Energy Technology Data Exchange (ETDEWEB)

A preliminary design effort directed toward a low concentration ratio photovoltaic array system capable of delivering multihundred kilowatts (300 kW to 1000 kW range) in low earth orbit is described. The array system consists of two or more array modules each capable of delivering between 113 kW to 175 kW using silicon solar cells or gallium arsenide solar cells, respectively. The array module deployed area is 1320 square meters and consists of 4356 pyramidal concentrator elements. The module, when stowed in the Space Shuttle's payload bay, has a stowage volume of a cube with 3.24 meters on a side. The concentrator elements are sized for a geometric concentration ratio (GCR) of six with an aperture area of .25 sq. m. The structural analysis and design trades leading to the baseline design are discussed. It describes the configuration, as well as optical, thermal and electrical performance analyses that support the ...

1983-07-01

384

IGENPRO knowledge-based digital system for process transient diagnostics and management  

Energy Technology Data Exchange (ETDEWEB)

Verification and validation issues have been perceived as important factors in the large scale deployment of knowledge-based digital systems for plant transient diagnostics and management. Research and development (R&D) is being performed on the IGENPRO package to resolve knowledge base issues. The IGENPRO approach is to structure the knowledge bases on generic thermal-hydraulic (T-H) first principles and not use the conventional event-basis structure. This allows for generic comprehensive knowledge, relatively small knowledge bases and above all the possibility of T-H system/plant independence. To demonstrate concept feasibility the knowledge structure has been implemented in the diagnostic module PRODIAG. Promising laboratory testing results have been obtained using data from the full scope Braidwood PWR operator training simulator. This knowledge structure is now being implemented in the transient management module PROMANA to treat ...

1997-12-31

385

Development of functional foods for radiation workers  

Energy Technology Data Exchange (ETDEWEB)

In searching modulators of immunity and hematopoiesis among natural products, being used as foods, six herbs exhibited lymphocyte proliferation in vitro, and six exhibited augmentation of hematopoietic cell growth. The combined treatments showed synergistic effects of lymphocyte proliferation and of hematopoietic cell growth. On the other hand, we found four effective oriental medicinal prescriptions, used as energy tonic or blood-building decoctions, for survival and regeneration of hematopoietic cells and for protection of stem cells of intestinal crypt in irradiated mice. On the basis of these results, extracts from combinations of herbs were made in expectation of higher effects in the three respects. In immuno modulation activity by the two combinations of herbs was confirmed in mice. In culture of bone narrow cells, growth improvement of non-adherent precursor and induction of cytokine expression by herb mixture extracts were observed. In ...

2000-03-01

386

Development of an efficient, low-NOx domestic gas-range cooktop. Phase 3. Annual technical report, January 1986-December 1986  

Science.gov (United States)

The objective of the program is to develop a domestic cooktop with low-NOx emissions and high efficiency. During the first two phases of the program, three design concepts were developed, and two versions of developmental prototypes using the IR-Jet approach were fabricated and tested. The third phase was initiated to address the design issues of burner turndown and modulation and to conduct the field test of a prototype with one IR-Jet and three conventional burners. Two prototypes containing one IR-Jet and three conventional burners and utilizing blower speed control for air/gas modulation were fabricated. One unit employed a brushless dc motor and the other a 2-pole ac motor. The ac motor prototype was field tested. Field testing showed the need for a mechanical air/gas valve for modulation and for a 1500 Btu/hr simmer setting. A 4-inch-diameter stepped-tile configuration provided input rates from 1500 to 8000 Btu/hr. A ...

1987-06-01

387

Carbon dioxide absorption contactors: hollow fibre membranes and packed absorption columns  

Energy Technology Data Exchange (ETDEWEB)

One of the important aspects in an absorption system is the effectiveness in which the gas and liquid phases come into contact with each other. An effective absorption process will provide sufficient contacting area for the gas and liquid phases to interact upon. With this in mind, work was conducted to evaluate carbon dioxide (CO{sub 2}) absorption into aqueous solutions of monoethanolamine (MEA) using two different types of contacting devices: gas absorption membrane (GAM) modules and traditional packed columns. The performance of these two absorption devices was compared to one another using the overall mass transfer coefficient (K{sub G}a{sub v}) as a basis. The GAM module contained microporous polypropylene hollow fibre membranes and the packed absorption column contained Sulzer DX structured packing. The results indicate that GAM modules tend to have slightly larger K{sub G}a{sub v} values, potentially opening the ...

2003-07-01

388

Boat sampling technique for assessment of ageing of components  

International Nuclear Information System (INIS)

Boat sampling technique (BST) is a surface sampling technique, which has been developed for obtaining, in-situ, metal samples from the surface of an operating component without affecting its operating service life. The BST is non-destructive in nature and the sample is obtained without plastic deformation or without thermal degradation of the parent material. The shape and size of the sample depends upon the shape of the cutter and the surface geometry of the parent material. Miniature test specimens are generated from the sample and the specimens are subjected to various tests, viz. Metallurgical Evaluation, Metallographic Evaluation, Micro-hardness Evaluation, sensitisation test, small punch test etc. to confirm the integrity and assessment of safe operating life of the component. This paper highlights design objective of boat sampling technique, description of sampling module, sampling cutter and its performance evaluation, cutting process, boat samples, ...

2006-11-01

389

Blind source separation of convolutive mixtures of non circular linearly modulated signals with unknown baud rates  

CERN Document Server

This paper addresses the problem of blind separation of convolutive mixtures of BPSK and circular linearly modulated signals with unknown (and possibly different) baud rates and carrier frequencies. In previous works, we established that the Constant Modulus Algorithm (CMA) is able to extract a source from a convolutive mixture of circular linearly modulated signals. We extend the analysis of the extraction capabilities of the CMA when the mixing also contains BPSK signals. We prove that if the various source signals do not share any non zero cyclic frequency nor any non conjugate cyclic frequencies, the local minima of the constant modulus cost function are separating filters. Unfortunately, the minimization of the Godard cost function generally fails when considering BPSK signals that have the same rates and the same carrier frequencies. This failure is due to the existence of non-separating local minima of the Godard cost function. In order ...

2011-01-01

390

15th Workshop on Crystalline Silicon Solar Cells and Modules: Materials and Processes; Extended Abstracts and Papers  

Energy Technology Data Exchange (ETDEWEB)

The National Center for Photovoltaics sponsored the 15th Workshop on Crystalline Silicon Solar Cells & Modules: Materials and Processes, held in Vail, CO, August 7-10, 2005. This meeting provided a forum for an informal exchange of technical and scientific information between international researchers in the photovoltaic and relevant non-photovoltaic fields. The workshop addressed the fundamental properties of PV silicon, new solar cell designs, and advanced solar cell processing techniques. A combination of oral presentations by invited speakers, poster sessions, and discussion sessions reviewed recent advances in crystal growth, new cell designs, new processes and process characterization techniques, and cell fabrication approaches suitable for future manufacturing demands. The theme of this year's meeting was 'Providing the Scientific Basis for Industrial Success.' Specific sessions during the workshop included: Advances in crystal ...

2005-11-01

391

Using n-ZnO-Al as window layer in pilot production of CIGSSe solar modules: Status and trends. Status of CIGSSe pilot scale production at Munich; Einsatz von n-ZnO:Al als Fensterschicht in der Pilotfertigung von CIGSSe-Solarmodulen: Status and Entwicklung. Status der CIGSSe-Pilotfertigung in Muenchen  

Energy Technology Data Exchange (ETDEWEB)

Shell Solar GmbH is working on a variant of the so-called stacked elemental layer process for CIGSSe absorber production. The metal films resp. the selenium are deposited on the Mb electrode at room temperature by DC sputtering (CIG) or evaporation (Se) and then processed into semiconductors by rapid thermal annealing (RTP). Currently, the mean efficiency of the pilot plant is i 12.6 {+-} 0.2 % for non-sealed 30 x 30 cm{sup 2} modules, the key efficiency is 13.0 %. In addition to the 30 x 30 cm{sup 2} pilot line, a small series of 60x90cm2 modules was constructed in December 2004. Here, the mean efficiency was 13.0 percent while the average module power was higher than 60 W. The contribution also describes investigations of ceramically sputtered n-ZnO:Al layers with reduced Al concedntrations of 1 percent and on reactively sputtered n-ZnO.Al layers from the double roller magnetron. (orig.) [German] Bei Shell Solar GmbH wird ...

2005-07-01

392

Wettability and osteoblast cell response modulation through UV laser processing of nylon 6,6  

British Library Electronic Table of Contents (United Kingdom)

With an ageing population the demand for cheap, efficient implants is ever increasing. Laser surface treatment offers a unique means of varying biomimetic properties to determine generic parameters to predict cell responses. This paper details how a KrF excimer laser can be employed for both laser-induced patterning and whole area irradiative processing to modulate the wettability characteristics and osteoblast cell response following 24h and 4 day incubation. Through white light interferometry (WLI) it was found that the surface roughness had considerably increased by up to 1.5mm for the laser-induced patterned samples and remained somewhat constant at around 0.1mm for the whole area irradiative processed samples. A sessile drop device determined that the wettability characteristics diffe...

2011-01-01

393

Wear particles, periprosthetic osteolysis and the immune system  

British Library Electronic Table of Contents (United Kingdom)

The immune system modulates many key biological processes in humans. However, the exact role of the immune system in particle-associated periprosthetic osteolysis is controversial. Human tissue retrieval studies, in vivo and in vitro experiments suggest that the immune response to polymer particles is non-specific and macrophage-mediated. Lymphocytes may modulate this response. However direct lymphocyte activation by polymer particle-protein complexes seems unlikely. However, metallic byproducts may complex with serum proteins and lead to a Type IV, lymphocyte-mediated immune reaction. In predisposed individuals, this reaction may rarely lead to persistent painful joint effusions, necessitating debridement and excision of the bearing surfaces of the prosthesis. In these patients, retrieved...

2007-01-01

394

Waste Receiving and Processing Facility Module 2A: Advanced Conceptual Design Report. Volume 1  

Energy Technology Data Exchange (ETDEWEB)

This ACDR was performed following completed of the Conceptual Design Report in July 1992; the work encompassed August 1992 to January 1994. Mission of the WRAP Module 2A facility is to receive, process, package, certify, and ship for permanent burial at the Hanford site disposal facilities the Category 1 and 3 contact handled low-level radioactive mixed wastes that are currently in retrievable storage at Hanford and are forecast to be generated over the next 30 years by Hanford, and waste to be shipped to Hanford from about DOE sites. This volume provides an introduction to the ACDR process and the scope of the task along with a project summary of the facility, treatment technologies, cost, and schedule. Major areas of departure from the CDR are highlighted. Descriptions of the facility layout and operations are included.

1994-03-01

395

Undergraduate teaching of nuclear medicine: a comparison between Central and Eastern Europe and European Union countries  

International Nuclear Information System (INIS)

This paper overviews the curricula of nuclear medicine (NM) undergraduate training in 34 Central and Eastern European (CEE) and 37 European Union (EU) medical faculties. The data show enormous variation in the number of hours devoted to nuclear medicine, varying between 1-2 to 40 hours and highly differentiated concepts/ideas of nuclear medicine training in particular countries. In most EU countries this teaching is integrated with that of radiology or clinical modules, also with training in clinical physiology. In many CEE countries teaching and testing of NM are independent, although integration with other teaching modules is frequent. The paper discusses the differences in particular approaches to nuclear medicine teaching. (author)

396

Thermal-mechanical behavior of the bonding wire for a power module subjected to the power cycling test  

British Library Electronic Table of Contents (United Kingdom)

Two analytical methods were proposed in this research, coupled electro-thermal finite element (FE) analysis and thermal-mechanical FE analysis, to analyze the mechanical behavior of bonding wire of power module under cyclic power loads, and the International Electrotechnical Commission standard is adopted in conducting a power cycling test. The exterior temperature distribution was measured by an infrared thermometer. Moreover, the junction temperature is calculated from the given thermal impedance of the semiconductor chip, chip power loss, and case temperature. Subsequently, the simulated temperature distribution via electro-thermal FE analysis is compared with experimental results to validate the methodology used in the aforementioned analysis. The analysis shows compressive stress at t...

2011-01-01

397

The development of technology on chicken yard design and its environment control  

Energy Technology Data Exchange (ETDEWEB)

The objective of this study is development of technology on chicken yard design and its environment control. For this objective, the micro processor interface techniques and related programming techniques have been surveyed, and the chicken yard environment monitoring system has been developed that equipped with micro computer and signal measurement module. Software has also been developed that operated the system and analyzes measured data. By using micro computer and signal input/output module, the system can have various functions, such as monitoring, alarm, and data analysis function. Three dimensional graphic modeling of a chicken yard is performed using graphic package in this study. Application of three dimensional modeling technique make it easy to design chicken yard. 9 figs. (Author)

1996-04-01

398

The Benchmark Test Results of QNX RTOS  

International Nuclear Information System (INIS)

A Real-Time Operating System(RTOS) is an Operating System(OS) intended for real-time applications. Benchmarking is a point of reference by which something can be measured. The QNX is a Real Time Operating System(RTOS) developed by QSSL(QNX Software Systems Ltd.) in Canada. The ELMSYS is the brand name of commercially available Personal Computer(PC) for applications such as Cabinet Operator Module(COM) of Digital Plant Protection System(DPPS) and COM of Digital Engineered Safety Features Actuation System(DESFAS). The ELMSYS PC Hardware is being qualified by KTL(Korea Testing Lab.) for use as a Cabinet Operator Module(COM). The QNX RTOS is being dedicated by Korea Atomic Energy Research Institute (KAERI). This paper describes the outline and benchmarking test results on Context Switching, Message Passing, Synchronization and Deadline Violation of QNX RTOS under the ELMSYS PC platform

2010-10-01

399

TUNABLE FIBER FABRY-PEROT FILTER FOR OPTICAL CARRIER-SUPPRESSION AND SINGLE-SIDEBAND MODULATION IN RADIO OVER FIBER LINKS  

British Library Electronic Table of Contents (United Kingdom)

A novel method of simultaneous realization of optical carrier-suppression and single-sideband modulation using fiber Fabry-Perot tunable filter is presented. In order to enhance transmission performance of radio over fiber links, we use a fiber Fabry-Perot tunable filter to filter out one sideband as well as suppress the optical carrier power. The results demonstrate 20.5dB and 14.2dB improvement in the signal noise ratios when 18GHz and 10GHz microwave signals carrying 5Mbit/s quadrature-phase-shift-keyed (QPSK) format data is transmitted over 35 km single mode fiber, respectively.

2006-01-01

400

Stability of modulation transfer function calibration of surface profilometers using binary pseudo-random gratings and arrays with nonideal groove shapes  

Energy Technology Data Exchange (ETDEWEB)

The major problem of measurement of a power spectral density (PSD) distribution of surface heights with surface profilometers arises due to the unknown Modulation Transfer Function (MTF) of the instruments, which tends to distort the PSD at higher spatial frequencies. The special mathematical properties of binary pseudo-random patterns make them an ideal basis for developing MTF calibration test surfaces. Two-dimensional binary pseudo-random arrays (BPRAs) have been fabricated and used for the MTF calibration of the MicroMap{trademark}-570 interferometric microscope with all available objectives. An investigation into the effects of fabrication imperfections on the quality of the MTF calibration and a procedure for accounting for such imperfections are presented.

2010-03-31

401

Spin qubits in antidot lattices  

DEFF Research Database (Denmark)

We suggest and study designed defects in an otherwise periodic potential modulation of a two-dimensional electron gas as an alternative approach to electron spin based quantum information processing in the solid-state using conventional gate-defined quantum dots. We calculate the band structure and density of states for a periodic potential modulation, referred to as an antidot lattice, and find that localized states appear, when designed defects are introduced in the lattice. Such defect states may form the building blocks for quantum computing in a large antidot lattice, allowing for coherent electron transport between distant defect states in the lattice, and for a tunnel coupling of neighboring defect states with corresponding electrostatically controllable exchange coupling between different electron spins.

2008-01-01

402

Spatial fluorescence cross correlation spectroscopy by means of a spatial light modulator  

CERN Document Server

Spatial Fluorescence Cross Correlation Spectroscopy is a rarely investigated version of Fluorescence Correlation Spectroscopy, in which the fluorescence signals from differ-ent observation volumes are cross-correlated. In the reported experiments, two observation volumes, typically shifted by a few $\\mu$m, are produced, with a Spatial Light Modulator and two adjustable pinholes. We illustrated the feasibility and potentiality of this technique by: i) measuring molecular flows, in the range 0.2 - 1.5 $\\mu$m/ms, of solutions seeded with fluorescent nanobeads or rhodamine molecules (simulating active transport phenomenons); ii) investigating the perme-ability of phospholipidic membrane of Giant Unilamellar Vesicles versus hydrophilic or hydrophobic molecules (in that case the laser spots were set on both sides of the mem-brane). Theoretical descriptions are proposed together with a discussion about FCS based, alternative methods.

2008-01-01

403

Private power in the country -- a chronology  

Energy Technology Data Exchange (ETDEWEB)

The chronology of installing solar power in a rural area of Ontario is described. The installation took all of seven years, and was characterized by a lot of joy, but also a lot of heartache and hardship, all of which are chronicled in this article. The project started with four solar modules generating 300 watts, nickel cadmium batteries of 225 Ah, an inverter of 600 watt, and a three-cylinder 6.5 Kw water-cooled propane generator. Today, nearly seven years later, the installation consists of 18 solar modules supplying 1350 watts of power, lead-acid batteries of 2770 Ah, a 2500 watt inverter, a one cylinder, 5.5 kw propane-gasoline generator, a heated, underground generator house, complete with an amp-hour meter and MPPT charge controller.

2003-06-30

404

Photobioreactor for cultivation and real-time, in-situ measurement of O2 and CO2 exchange rates, growth dynamics, and of chlorophyll fluorescence emission of photoautotrophic microorganisms  

British Library Electronic Table of Contents (United Kingdom)

A detailed knowledge about the dynamics of phytoplanktonic photosynthesis and respiration is crucial for the determination of primary productivity in open oceans as well as for biotechnological applications. The dynamics are best studied in photobioreactors that are able to simulate natural conditions in such, that light can be modulated not only diurnally but also mimicking effects of solar elevation angle from sunrise to sunset, variable cloudiness, light modulation in refractory sun flecks due to water waves, or light intermittence due to turbulent flow in dense suspensions. In addition, high performance photobioreactors ought to be able to monitor in real time photosynthetic and respiratory activities as well as culture growth. Here, we demonstrate performance of a newly designed bench...

2009-01-01

405

P2Y receptors on astrocytes and microglia mediate opposite effects in astroglial proliferation  

British Library Electronic Table of Contents (United Kingdom)

Nucleotides released upon brain injury signal to astrocytes and microglia playing an important role in astrogliosis, but the participation of microglia in the purinergic modulation of astrogliosis is still unclear. Highly enriched astroglial cultures and co-cultures of astrocytes and microglia were used to investigate the influence of microglia in the modulation of astroglial proliferation mediated by nucleotides. In highly enriched astroglial cultures, adenosine-5?-triphosphate (ATP), adenosine 5?-O-(3-thio)-triphosphate (ATP?S), adenosine 5?-O-(3-thio)-diphosphate (ADP?S; 0.01?1?mM), and adenosine-5?-diphosphate (ADP; 0.1?1?mM) increased proliferation up to 382%, an effect abolished in co-cultures containing 8% of microglia. The loss of ATP proliferative effect in co-cultures is supporte...

2011-01-01

406

On the role of the Jeffreys'sheltering mechanism in the sustain of extreme water waves  

CERN Document Server

The effect of the wind on the sustain of extreme water waves is investigated experimentally and numerically. A series of experiments conducted in the Large Air-Sea Interactions Facility (LASIF) showed that a wind blowing over a strongly nonlinear short wave group due to the linear focusing of a modulated wave train may increase the life time of the extreme wave event. The expriments suggested that the air flow separation that occurs on the leeward side of the steep crests may sustain longer the maximum of modulation of the focusing-defocusing cycle. Based on a Boundary-Integral Equation Method and a pressure distribution over the steep crests given by the Jeffreys'sheltering theory, similar numerical simulations have confirmed the experimental results

2006-01-01

407

On and off-axis ECH modulation experiments on RTP  

Energy Technology Data Exchange (ETDEWEB)

In a new series of modulated electron cyclotron heating (MECH) on RTP the MECH power was deposited either on-axis or off-axis in plasmas with different values of the plasma current (I{sub p}). Besides confirming all previous MECH results on RTP, the new data can be simulated by assuming a radial profile of the incremental diffusivity ({chi}{sup inc}) that is constant ({chi}{sup inc} < 1 m{sup 2}/s) inside the sawtooth region, makes a sharp step near the inversion radius, and has an offset parabolic profile elsewhere with a value of {chi}{sup inc} {approx} 6 m{sup 2}/s at r/a {approx} 0.6. No significant dependence of {chi}{sup inc} on q{sub a} is observed apart from the position of the transition from low to high {chi}{sup inc}. (author) 5 refs., 4 figs.

1994-12-31

408

Nonlinear evolution of protostellar disks and light modulations in young stellar objects  

International Nuclear Information System (INIS)

An evolutionary model of dynamical processes in protostellar disks is described and illustrated with graphs of typical results. The effective transport mechanisms are discussed, including thermal convection, nonaxisymmetric gravitational instabilities in the outer regions of disks, and wave propagation. Consideration is then given to the stages of dynamical evolution, FU Ori outburst phenomena, unsteady accretion-disk flows, and nonlinear feedback as a mechanism to modulate mass transfer. The simulations show that mass redistribution is determined by angular-momentum transfer, which in turn is regulated by the effective viscosity generated by convectively driven turbulence. Significant mass transfer occurs as a result of mixing of infalling material with disk gas and is affected by the tidal torque associated with the growth of nonaxisymmetric disturbances in the outer disk. The time scale for disk evolution is found to be about 1 Myr. 72 refs.

1989-10-05

409

Naval Sea Systems Command occupational safety and health record-keeping system. Hazardous Materials Control Module. Program maintenance manual  

Energy Technology Data Exchange (ETDEWEB)

Since August 1984, the MITRE Corporation has been supporting the Naval Sea Systems Command (NAVSEA) and the Naval Medical Command (NAVMEDCOM) in their joint efforts to enhance the Navy Occupational Health Information Management System (NOHIMS). The goal of the enhancement effort was to create a comprehensive occupational health and safety system for Navy industrial facilities by expanding upon the original NOHIMS functions and adding modules for hazard deficiency abatement, hazardous-material control, injury claims and compensation, and safety and health training. To meet this goal, MITRE developed an enhanced industrial subsystem, referred to as the Occupational Safety and Health Record Keeping System (OSHRKS), using a prototyping approach and a public-domain data base-management software package, the Veterans Administration's (VA's) FileManager (FileMan).

1987-06-01

410

Microwave excitation of a CO/sub 2/ laser. Master's thesis  

Energy Technology Data Exchange (ETDEWEB)

A flowing carbon dioxide laser was operated at low pressures up to 4 torr. Excitation of the laser was provided using various combinations of direct current (DC), pulsed microwave, and continuous wave (CW) microwave excitation. The microwaves were in the 2.45 GHz band and were coupled into the gas using a slow-wave interdigital transmission line. Laser output of 25 milliwatts (mw) was achieved using a DC discharge only. A combination of a DC discharge and pulsed microwaves doubled the output and resulted in some modulation. Changing the laser gas mixture and pulsed microwave field characteristics allowed some flexibility in the modulation. Lasing was not achieved with excitation from the CW microwaves alone due to the formation of localized discharges. Using pulsed microwaves to sustain the discharge and CW microwaves to pump the laser, a quasi-CW output of 55 mw was achieved.

1983-12-01

411

Mechanical design of a PERMCAT reactor module  

International Nuclear Information System (INIS)

The PERMCAT is a membrane reactor proposed for processing fusion reactor plasma exhaust gas: tritium removal is obtained by isotopic swamping operating in counter-current mode. In this work, a membrane reactor using a permeator tube of length about 500 mm produced via diffusion welding of Pd-Ag thin foils is described. An appropriate mechanical design of the membrane module has been developed in order to avoid any significant compressive and bending stresses on the very long and thin wall permeator tube: two expanded bellows have been applied to the Pd-Ag tube, so that it has been pre-tensioned before operating. The elongation of the metal permeator under hydrogenation has been theoretically estimated and experimentally verified for properly designing the membrane reactor.

2007-02-01

412

MSHA (Mine Safety and Health Administration) approved mine rescue - training module (coal): fires, fire fighting, and explosions. Mine rescue team series  

Science.gov (United States)

Mine rescue teams frequently must fight fires and guard against the propagation of fires or explosions during a rescue and recovery operation. The team's ability to fight fires depends a great deal on hands-on experience with different fire fighting agents and equipment. The team's work includes an assessment of fire conditions, mine fire gases and other potential hazards associated with fire fighting activity. This training module covers the underlying principles of the fire triangle and the different methods for controlling, containing and extinguishing fires in a mine. The manual also covers fire-fighting equipment, considerations involved in a sealing operation and the cause-effect of explosions.

1984-01-01

413

Implementation of an OFDM underwater acoustic communication system on an underwater vehicle with multiprocessor structure  

British Library Electronic Table of Contents (United Kingdom)

Orthogonal frequency division multiplexing (OFDM) can fully use the frequency band and transmit data at high speeds. The ADSP-TS101 is a high performance digital signal processor (DSP) with good properties that include parallel processing and a high speed. Aimed at the real-time processing requirement of the OFDM algorithm, an underwater acoustic communication system with real-time processing capability is carried out. The system is mainly composed of multiple ADSP-TS101s, a multi-channel synchronous sample module and a field programmable gate array (FPGA) chip. The multiprocessor structure is made up of a cluster/data flow associated multiprocessing parallel processing structure as the operation kernel, and a multi-channel synchronous sample module is designed to realize no phase warp amo...

2007-01-01

414

Gonadal hormone modulation of neurogenesis in the dentate gyrus of adult male and female rodents  

British Library Electronic Table of Contents (United Kingdom)

Gonadal hormones modulate neurogenesis in the dentate gyrus differentially in male and female adult rodents. Neurogenesis is comprised of at least two components: cell proliferation (the production of new cells) and cell survival (the number of new neurons that survive to maturity). Previous studies have found sex differences in the level of cell proliferation in the dentate gyrus only when comparing females in a high estrogen state to males. This review focuses on the effects of acute and chronic levels of estrogens or androgens on hippocampal neurogenesis in the adult male and female rodent. Evidence is also reviewed for the co-localization of androgen receptors and estrogen receptors (ER) with markers for cell proliferation or immature new cell survival. Briefly, evidence suggests that ...

2008-01-01

415

Forkhead box protein P1 as a downstream target of transforming growth factor-b induces collagen synthesis and correlates with a more stable plaque phenotype  

British Library Electronic Table of Contents (United Kingdom)

Objective: Atherosclerosis is an inflammatory disease, modulated by plaque stabilizing and de-stabilizing cell populations such as infiltrating monocytes and vascular smooth muscle cells (vSMCs). Transcription factors regulating proliferation and differentiation of atherosclerosis relevant cell types are of interest in this context. The forkhead box transcription factor FoxP1 modulates monocyte differentiation. We studied FoxP1 expression in atherosclerotic tissue, correlated FoxP1 expression with plaque characteristics and identified associations between FoxP1 and plaque proteins. Methods: 116 Atherosclerotic plaques from carotid endarterectomy samples were histologically classified (fibrous, fibroatheromatous, atheromatous) and subjected to semi-quantitative protein analysis. Macrophage,...

2011-01-01

416

Episodic Future Thinking Reduces Reward Delay Discounting through an Enhancement of Prefrontal-Mediotemporal Interactions  

British Library Electronic Table of Contents (United Kingdom)

Summary Humans discount the value of future rewards over time. Here we show using functional magnetic resonance imaging (fMRI) and neural coupling analyses that episodic future thinking reduces the rate of delay discounting through a modulation of neural decision-making and episodic future thinking networks. In addition to a standard control condition, real subject-specific episodic event cues were presented during a delay discounting task. Spontaneous episodic imagery during cue processing predicted how much subjects changed their preferences toward more future-minded choice behavior. Neural valuation signals in the anterior cingulate cortex and functional coupling of this region with hippocampus and amygdala predicted the degree to which future thinking modulated individual preference fu...

2010-01-01

417

Demonstration drop test and design enhancement of the CANDU spent fuel storage basket in dry storage facility  

British Library Electronic Table of Contents (United Kingdom)

A dry interim storage facility has been constructed at the Wolsung power plant in Korea. This dry storage facility has seven separated modules. There are 40 long slender cylinders in one module. In one cylinder, ten baskets where sixty CANDU spent fuel bundles are loaded are stacked and stored. For this dry storage facility, analyses and tests for hypothetical accident conditions that might occur while moving and storing the baskets into a cylinder were performed. In a demonstration test, one of test basket models did not satisfy one of the safety-related requirements. Thus, the revised basket designs were generated using a structural evaluation based on finite element analyses and specimen tests. Among these revised designs, one design was chosen as a final revised basket design. The fina...

2011-01-01

418

Conceptual design of a low-temperature radiation-hard tracker detector  

CERN Document Server

Silicon sensors have about ten times improved radiation hardness around 130 K temperature, compared with the state-of-art sensors close to room temperature. This is based on the Lazarus effect studied by the RD39 Collaboration of CERN. Other benefits of low temperatures will also be discussed. We shall describe the conceptual design of low-mass detector modules cooled using two-phase flow of argon in miniature cooling pipes integrated in the module structure between the sensors and the readout hybrid circuit. The main engineering features of the cooling system and mechanical support structures are discussed, as well as the benefits arising from the operation of the tracker under cryogenic vacuum. 4 Refs.

2003-01-01

419

Binary pseudo-random grating as a standard test surface formeasurement of modulation transfer function of interferometricmicroscopes  

Energy Technology Data Exchange (ETDEWEB)

The task of designing high performance X-ray optical systemsrequires the development of sophisticated X-ray scattering calculationsbased on rigorous information about the optics. One of the mostinsightful approaches to these calculations is based on the powerspectral density (PSD) distribution of the surface height. The majorproblem of measurement of a PSD distribution with an interferometricand/or atomic force microscope arises due to the unknown ModulationTransfer Function (MTF) of the instruments. The MTF characterizes theperturbation of the PSD distribution at higher spatial frequencies. Here,we describe a new method and dedicated test surfaces for calibration ofthe MTF of a microscope. The method is based on use of a speciallydesigned Binary Pseudo-random (BPR) grating. Comparison of atheoretically calculated PSD spectrum of a BPR grating with a spectrummeasured with the grating provides the desired calibration of theinstrumental MTF. The theoretical ...

2007-07-25

420

Application of Vertically Integrated Electronics to Intelligent Trackers  

CERN Document Server

At Super-LHC luminosity it is expected that the standard suite of L1 triggers for CMS will saturate. Information from the tracker will be needed to reduce trigger rates to satisfy the L1 bandwidth. Tracking trigger modules which correlate information from closely-spaced sensor layers to form an on-detector momentum filter are being developed by several groups. We report on a trigger module design which utilizes three dimensional IC technology to incorporate chips which are connected both to the top and bottom sensor, providing the ability to filter information locally. A demonstration chip, the VICTR, has been submitted to the Chartered/Tezzaron two-tier 3D run coordinated by Fermilab. We report on the 3D design concept, the status of the VICTR chip and associated sensor integration utilizing oxide bonding.

2010-01-01

421

Adding channels with PSBT format at 40Gbit/s in an existing 10Gbit/s optical network  

British Library Electronic Table of Contents (United Kingdom)

Until recently, the wavelength-division-multiplexed (WDM) transmission system has reached record capacities and distances due to innovations such as FEC (Forward Error Correction), distributed Raman amplification, new transmission fiber and advanced optical format. Optical-communication systems exclusively employed conventional On-Off Keying signals in either Non-Return-To-Zero (NRZ) or Return-To-Zero (RZ) format. Recently a number of advanced modulation formats have attracted attention. Some of these formats carry information through On-Off-Keying but also modulate the optical phase in order to enhance the robustness of signal to chromatic dispersion, optical filtering and non-linearities. Through extensive sets of simulation results, we showed that it is possible to replace a channel wit...

2011-01-01

422

Adalimumab treatment in Crohn's disease does not induce early changes in regulatory T cells  

British Library Electronic Table of Contents (United Kingdom)

Abstract Objective. Anti-TNF-a antibodies has been suggested to modulate regulatory T cell (Treg) percentages in rheumatoid arthritis, but results from studies of Crohn's disease (CD) are conflicting. We investigated dynamic changes of circulating Tregs in CD during treatment with the anti-TNF-a-antibody adalimumab (Humira, Abbott Laboratories A/S, Emdrupvej 28C, DK-2100 Copenhagen). Material and methods. Blood samples from 26 CD patients were analysed using flow cytometry before and 1 and 26 weeks after initiation of adalimumab treatment to determine the percentage of Tregs among CD4++ T cells. Results. In spite of a significant decline in disease activity scores and biochemical markers of inflammation, during the first week of treatment, we did not observe early modulating effects of ada...

2011-01-01

423

A numerical study on the long term thermo-poroelastic effects of cold water injection into naturally fractured geothermal reservoirs  

British Library Electronic Table of Contents (United Kingdom)

The residing fracture system and the prevailing in situ stresses have a significant impact on fluid flow and heat transfer in crystalline rocks. The long term response of fracture systems to changes in effective stresses, in particular the long term geo-mechanical effects of thermal stresses on reservoir characteristics is of particular interest to the geothermal industry.In this paper, a geothermal reservoir model is presented, in which a thermo-poroelastic finite element module is coupled to a fracture geomechanical module. This describes fracture closure as a function of effective stress and the changes in parameters, such as effective permeability, porosity and discrete fracture apertures. The novelty of this approach lies in its dynamic treatment of the characteristic properties of in...

2011-01-01

424

A comprehensive condition monitoring system for hydro-electric generating units  

Energy Technology Data Exchange (ETDEWEB)

This paper describes a comprehensive MCM [machine condition monitoring] program and suggested system for implementation in hydroelectric generating units. The system addresses all the major subsystems which make up the generating unit. A modular design means that it could be applicable in a wide variety of situations. Different subsystems may be included or excluded from the monitoring system as required. It may be used at individual plants as a stand alone system or network wide. An advanced processing and diagnostic module is included, again for use as an integral part of the system or as a stand alone analysis tool. Examples of the system's proposed data analysis and diagnostic abilities are also described using vibration signals as would be provided by the bearing module. (Author)

1994-04-01

425

Transverse and longitudinal excitation modes in interacting multispin systems  

International Nuclear Information System (INIS)

Magnetic excitation in coupled multispin system is studied theoretically focusing on Cu_2Fe_2Ge_4O_1_3 and Cu_2CdB_2O_6 as typical examples of such system. These compounds consist of spin dimer and spin monomer parts and show an antiferromagnetic phase transition at low temperatures due to the spin monomer part. A multispin containing a spin dimer and spin monomers is treated as a basis unit. The multispin forms a spin multiplet and its energy levels are separated into high and low regions reflecting the characteristic energies of the dimer and monomer parts. We regard the system as interacting multispins and apply an extended Holstein-Primakoff theory by introducing bosons for each energy level of a spin multiplet. In the low-energy region, the obtained magnon dispersion and dynamical spin correlation function agree quantitatively with experimental results of inelastic neutron scattering performed in Cu_2Fe_2Ge_4O_1_3. Analyzing dynamical spin ...

2010-08-01

426

The crystal structure of YPdSi, the isotopic compounds LnPdSi (Ln=Gd-Lu), and their structural relation to some other equiatomic compounds of the rare earth and transition metals with main group elements  

International Nuclear Information System (INIS)

The nine title compounds were prepared from the elements by arc-melting and subsequent heat treatment in resistance and high-frequency furnaces. The crystal structure of these isotypic compounds was determined for YPdSi from single-crystal X-ray diffractometer data: Pmmn, a = 430.8(1) pm, b = 1391.2(1) pm, c = 743.1(1) pm, Z = 8, R = 0.024 for 417 structure factors and 40 variable parameters. The crystal structures of the isotypic compounds GdPdSi and ErPdSi were also refined from single-crystal data. The structure is of a new type. It consists of condensed, six-membered rings of alternating palladium and silicon atoms with Pd-Si bond distances varying between 249.6 and 258.8 pm. These two-dimensionally infinite nets are connected to each other via weak Pd-Si and Si-Si bonds with bond distances of 276.3 and 259.5 pm. The rare earth atoms are situated above and below the six-membered palladium-silicon rings in a manner as it is known for the aluminum atoms in the ...

427

c-JUN N-TERMINAL KINASE MODULATES OXIDANT STRESS AND PEROXYNITRITE FORMATION INDEPENDENT OF INDUCIBLE NITRIC OXIDE SYNTHASE IN ACETAMINOPHEN HEPATOTOXICITY  

UK PubMed Central (United Kingdom)

Acetaminophen (APAP) overdose, which causes liver injury in animals and humans, activates c-jun N-terminal kinase (JNK). Although it was shown that the JNK inhibitor SP600125 effectively reduced...Full Text Available

2010-07-01

428

Waste management facilities cost information for hazardous waste. Revision 1  

Energy Technology Data Exchange (ETDEWEB)

This report contains preconceptual designs and planning level life-cycle cost estimates for managing hazardous waste. The report`s information on treatment, storage, and disposal modules can be integrated to develop total life-cycle costs for various waste management options. A procedure to guide the US Department of Energy and its contractor personnel in the use of cost estimation data is also summarized in this report.

1995-06-01

429

Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, open-label, parallel group study in healthy subjects  

UK PubMed Central (United Kingdom)

The effect of abatacept, a selective T-cell co-stimulation modulator, on vaccination has not been previously investigated. In this open-label, single-dose, randomized, parallel-group, controlled study,...Full Text Available

2007-01-01

430

Up-Regulation of the RhoA/Rho-Kinase Signaling Pathway in Corpus Cavernosum from Endothelial Nitric-Oxide Synthase (NOS), but Not Neuronal NOS, Null Mice  

UK PubMed Central (United Kingdom)

We tested the hypothesis that the basal release of nitric oxide (NO) from endothelial cells modulates contractile activity in the corpus cavernosum (CC) via inhibition of the RhoA/Rho-kinase signaling...Full Text Available

2010-04-01

431

Unique Bell-shaped Voltage-dependent Modulation of Na+ Channel Gating by Novel Insect-selective Toxins from the Spider Agelena orientalis*  

UK PubMed Central (United Kingdom)

Spider venoms provide a highly valuable source of peptide toxins that act on a wide diversity of membrane-bound receptors and ion channels. In this work, we report isolation, biochemical analysis, and...Full Text Available

2010-06-11

432

Targeting AMP-activated protein kinase in adipocytes to modulate obesity-related adipokine production associated with insulin resistance and breast cancer cell proliferation  

UK PubMed Central (United Kingdom)

BackgroundAdipokines, e.g. TNFα, IL-6 and leptin increase insulin resistance, and consequent hyperinsulinaemia influences breast cancer progression. Beside its mitogenic...Full Text Available

433

Stabilization of synchrotron radiation x-ray beam by MOSTAB  

International Nuclear Information System (INIS)

Monochromator stabilization (MOSTAB) is a feedback control system to stabilize an x-ray beam of synchrotron radiation. It applies a feedback voltage to a piezo electric transducer attached to a double-crystal monochromator. We developed MOSTAB modules and examined their performances using SPring-8 beamlines. The x-ray beam position stabilization using MOSTAB was realized simultaneously with the x-ray beam intensity stabilization. As an example of its application, we performed EXAFS measurement with MOSTAB. (author)

2003-05-01

434

Single-mode 30 MW CO/sub 2/ laser system for 16. mu. m Raman scattering in parahydrogen  

Energy Technology Data Exchange (ETDEWEB)

A CO/sub 2/ laser chain able to supply approx.=30 MW on a single mode TEM/sub 00/ is described. The coupling of a modified Lumonics 101 module with a low-pressure cell constitues the oscillator and two further Lumonics 103 stages two amplifiers. The final pulse achieves the energy of 4.0 J with 90% of this energy in a peak of 100 ns FWHM.

1983-01-11

435

Single Particle Tracking of ?7 Nicotinic AChR in Hippocampal Neurons Reveals Regulated Confinement at Glutamatergic and GABAergic Perisynaptic Sites  

UK PubMed Central (United Kingdom)

α7 neuronal nicotinic acetylcholine receptors (α7-nAChR) form Ca2+-permeable homopentameric channels modulating cortical network activity and cognitive processing....Full Text Available

436

Single Atom Detection With Optical Cavities  

CERN Document Server

We present a thorough analysis of single atom detection using optical cavities. The large set of parameters that influence the signal-to-noise ratio for cavity detection is considered, with an emphasis on detunings, probe power, cavity finesse and photon detection schemes. Real device operating restrictions for single photon counting modules and standard photodiodes are included in our discussion, with heterodyne detection emerging as the clearly favourable technique, particularly for detuned detection at high power.

2008-01-01

437

Shuttle Showcase: STS-124  

National Aeronautics and Space Administration (NASA)

The second in a series of flights to assemble the Japanese segment of the International Space Station saw the mammoth Kibo module delivered to the complex complements of Discovery and its crew on the STS-124 mission. Kibo, the Japanese word for u201chopeu201d would house dozens of experiments and serve as a platform for external payloads brought to the complex on subsequent Shuttle flights and the Japanese u201cKounotoriu201d H-2 Transfer Vehicle cargo ship.

2011-07-10

438

Searches for Fast Radio Transients  

CERN Document Server

We discuss optimal detection of fast radio transients from astrophysical objects while taking into account the effects of propagation through intervening ionized media, including dispersion, scattering and scintillation.Our analysis applies to the giant-pulse phenomenon exhibited by some pulsars, for which we show examples, and to radio pulses from other astrophysical sources, such as prompt radio emission from gamma-ray burst sources and modulated signals from extra-terrestrial civilizations.

2003-01-01

439

SAMFT1D: Single-phase and multiphase flow and transport in 1 dimension. Version 2.0, Documentation and user`s guide  

Energy Technology Data Exchange (ETDEWEB)

This report documents a one-dimensional numerical model, SAMFT1D, developed to simulate single-phase and multiphase fluid flow and solute transport in variably saturated porous media. The formulation of the governing equations and the numerical procedures used in the code for single-phase and multiphase flow and transport are presented. The code is constructed to handle single-phase as well as two or three-phase flow conditions using two integrated sets of computational modules. The fully implicit scheme is used in the code for both single-phase and multiphase flow simulations. Either the Crank-Nicholson scheme or the fully implicit scheme may be used in the transport simulation. The single-phase modules employ the Galerkin and upstream weighted residual finite element techniques to model flow and transport of water (aqueous phase) containing dissolved single-species contaminants concurrently or sequentially, and include the treatment of ...

1991-09-01

440

Representations of the conformal Lie algebra in the space of tensor densities on the sphere  

CERN Document Server

Let ${\\mathcal F}_\\lambda(\\mathbb{S}^n)$ be the space of tensor densities on $\\mathbb{S}^n$ of degree $\\lambda$. We consider this space as an induced module of the nonunitary spherical series of the group $\\mathrm{SO}_0(n+1,1)$ and classify $(\\mathrm{so}(n+1,1),\\mathrm{SO}(n+1))$-sim$unitary submodules of ${\\mathcal F}_\\lambda(\\mathbb{S}^n)$ as a function of $\\lambda$.

2003-01-01

441

Radiations against tumors: a bit old-fashioned?; Rayonnements contre tumeurs: un rien demode?  

Energy Technology Data Exchange (ETDEWEB)

The proton therapy gives an irradiation adapted to the shape and the depth of tumors ( eyes, head and neck) with a millimetric, even sub millimetric precision for the ophthalmological tumors. It is equally an excellent tool for the pediatrics tumors. For numerous treatments in France the proton therapy is associated to the photons treatments (x radiation). however, others physical treatments could modulate the medical offer, such thermal therapy or treatments by ultrasonic waves. (N.C.)

2004-09-01

442

Pore properties and pharmacological features of the P2X receptor channel in airway ciliated cells  

UK PubMed Central (United Kingdom)

Airway ciliated cells express an ATP-gated P2X receptor channel of unknown subunit composition (P2Xcilia) which is modulated by Na+ and by long exposures to ATP. P2Xcilia...Full Text Available

2006-03-15

443

PhET Teacher Ideas and Activities: Images from Convex Lenses  

Science.gov (United States)

This is an inquiry-based module created specifically for use with the PhET simulation Geometric Optics. It includes a lesson plan for teaching about convex lenses, step-by-step student directions, and a set of Power Point "clicker" questions for use as warm-up questions or informal assessment. This resource is part of a larger collection of interactive Java simulations for students of physics, developed by the Physics Education Technology project at the University of Colorado.

2009-05-20

444

Optimization of doubly Q-switched lasers with both an acousto-optic modulator and a GaAs saturable absorber  

Science.gov (United States)

A doubly Q-switched laser with both an acousto-optic (AO) modulator and a GaAs saturable absorber can obtain a more symmetric and shorter pulse with high pulse peak power, which has been experimentally proved. The key parameters of an optimally coupled doubly Q-switched laser with both an AO modulator and a GaAs saturable absorber are determined, and a group of general curves are generated for what we believe is the first time, when the single-photon absorption (SPA) and two-photon absorption (TPA) processes of GaAs are combined, and the Gaussian spatial distributions of the intracavity photon density and the initial population-inversion density as well as the influence of the AO Q-switch are considered. These key parameters include the optimal normalized coupling parameter, the optimal normalized GaAs saturable absorber parameters, and the normalized parameters of the AO Q-switch, which can maximize the output energy. Meanwhile, the ...

2007-08-20

445

Optical voltage reference  

Energy Technology Data Exchange (ETDEWEB)

An optical voltage reference for providing an alternative to a battery source. The optical reference apparatus provides a temperature stable, high precision, isolated voltage reference through the use of optical isolation techniques to eliminate current and impedance coupling errors. Pulse rate frequency modulation is employed to eliminate errors in the optical transmission link while phase-lock feedback is employed to stabilize the frequency to voltage transfer function.

1992-12-31

446

Optical measurement of electron bunching in vacuum  

International Nuclear Information System (INIS)

We report the homodyne detection of phase modulation sidebands induced on a laser beam by a coherently bunched electron beam. This provides a sensitive and nonperturbing measurement of complex Fourier time series components of the electron density. A proof-of-principle measurement of the microwave frequency component of electron density in a crossed-field device, which agrees well with a calculation of the same quantity, is reported.

447

Motor drive chassis for the plutonium protection system  

International Nuclear Information System (INIS)

A motor drive chassis has been developed for use in the Plutonium Protection System. Rotation of the desired carrousel in a secure storage module is controlled by this chassis which supplies the power and drive pulses required by the carrousel motor. This work was sponsored by the Department of Energy/Office of Safeguards and Security (DOE/OSS) as part of the overall Sandia Fixed Physical Protection Program.

1998-10-12

448

Modulation of the axial water hydrogen-bonding properties by chemical modification of the substrate in resting state, substrate-bound heme oxygenase from Neisseria meningitidis; Coupling to the distal H-bond network via ordered water molecules  

UK PubMed Central (United Kingdom)

The hydrogen bonding of ligated water in ferric, high-spin, resting-state substrate complexes of heme oxygenase from Neisseria meningitidis has been systematically perturbed...Full Text Available

2006-05-17

449

Modulation of Retinoic Acid Receptor-related Orphan Receptor ? and ? Activity by 7-Oxygenated Sterol Ligands*  

UK PubMed Central (United Kingdom)

The retinoic acid receptor-related orphan receptors α and γ (RORα (NR1F1) and RORγ (NR1F3)) are orphan nuclear receptors and perform critical roles in regulation of development,...Full Text Available

2010-02-12

450

MicroRNAs Regulate Human Hepatocyte Nuclear Factor 4?, Modulating the Expression of Metabolic Enzymes and Cell Cycle*  

UK PubMed Central (United Kingdom)

Hepatocyte nuclear factor (HNF) 4α is a key transcription factor regulating endo/xenobiotic-metabolizing enzymes and transporters. We investigated whether microRNAs are involved in the regulation...Full Text Available

2010-02-12

451

Local analysis of three-dimensional air cooled condenser using a two-phase flow diagram  

Energy Technology Data Exchange (ETDEWEB)

This paper is concerned with the development and application of an analytical method for the performance prediction of air cooled condensers. A local analysis is employed in which the condenser is considered as a matrix of small basic heat transfer modules. For each element, local film coefficients for both the air and the condensing fluid are determined according to the existing local conditions, including the two-phase flow regime. The paper considers an application of the method to heat pump condensing.

1983-07-01

452

Live Brucella spp. fail to induce tumor necrosis factor alpha excretion upon infection of U937-derived phagocytes.  

UK PubMed Central (United Kingdom)

Tumor necrosis factor alpha (TNF-alpha) plays a central role in activation of first-line defenses of a host against foreign organisms. To determine whether Brucella infection modulated TNF-alpha production,...Full Text Available

1994-12-01

453

Isolated PWM DC-AC SICAM with an active capacitive voltage clamp[Pulse Density Modulated; Pulse Width Modulation  

Energy Technology Data Exchange (ETDEWEB)

In this report an isolated PWM DC-AC SICAM with an active capacitive voltage clamp is presented. AC-DC power supply is implemented in its simplest form: diode rectifier followed by a medium-size charge-storage capacitors and possibly with an EMC filter on the mains entrance. Isolation from the AC mains is achieved using a high frequency (HF) transformer, whose voltages are not audio-modulated. The latter simplifies the design and is expected to have many advantages over the approach where the transformer voltages are modulated in regards to the audio signal reference. Input stage is built as a DC-AC inverter (push-pull, half-bridge or a full-bridge) and operated with 50% duty cycle, with all the challenges to avoid transformer saturation and obtain symmetrical operation. On the secondary side the output section is implemented as rectifier+inverter AC-AC stage, i.e. a true bidirectional bridge, which operation is aimed towards amplification of ...

2004-03-15

454

How does immune challenge inhibit ingestion of palatable food? Evidence that systemic lipopolysaccharide treatment modulates key nodal points of feeding neurocircuitry  

UK PubMed Central (United Kingdom)

Immune challenge induces behavioral changes including reduced ingestion of palatable food. Multiple pathways likely contribute to this effect, including viscerosensory pathways controlling hypothalamic...Full Text Available

2008-11-01

455

Homocysteine effects classical pathway of GPCR down regulation: G?q/11, G?12/13, Gi/o  

UK PubMed Central (United Kingdom)

G protein-coupled receptors (GPCRs) are known to modulate intracellular effectors involved in cardiac function. We recently reported homocysteine (Hcy)-induced ERK-phosphorylation was suppressed...Full Text Available

2009-01-01

456

Feasibility Study of Hydrogen Production from Existing Nuclear Power Plants Using Alkaline Electrolysis  

Energy Technology Data Exchange (ETDEWEB)

The mid-range industrial market currently consumes 4.2 million metric tons of hydrogen per year and has an annual growth rate of 15% industries in this range require between 100 and 1000 kilograms of hydrogen per day and comprise a wide range of operations such as food hydrogenation, electronic chip fabrication, metals processing and nuclear reactor chemistry modulation.

2008-12-31

457

Extending purchasing with document management, workflow and the internet  

Energy Technology Data Exchange (ETDEWEB)

Sandia is a national security laboratory operated for the U.S. department of Energy by the Sandia Corporation, a Lockheed Martin Company. Sandia designs all non-nuclear components for the nation's nuclear weapons, performs a wide variety of energy research and development projects, and works on assignments that respond to national security threats - both military and economic. They encourage and seek partnerships with appropriate U.S. industry and government groups to collaborate on emerging technologies that support their mission. Today, Sandia has two primary facilities, one in Albuquerque, New Mexico, and one in Livermore, California. They employ about 7,600 people and manage about $1.4 billion of work per year. In 1995, a decision was made to move from their in-house developed systems to commercial software. This decision was driven partly by Y2K compliance issues associated with the existing operating system and support environment. Peoplesoft was selected for human ...

2000-02-09

458

Dynamics of electrooptic bistable devices with delayed feedback  

Science.gov (United States)

The dynamic behavior of electrooptic bistable devices with delayed feedback is investigated theoretically and experimentally. The operation principle of the system is analyzed by the method of iterated maps. Stable, bistable, periodic, higher periodic, and chaotic solutions are discussed and realized experimentally by using an integrated Mach-Zehnder interferometer on LiNbO3 as a basic nonlinear element. Taking into account the periodic modulator characteristic, the application of this device as a simple and fast bistable and monostable multivibrator is demonstrated. In addition, the synchronization properties of the astable multivibrator are investigated.

1982-12-01

459

Drying of medicinal plants with solar energy utilization  

Energy Technology Data Exchange (ETDEWEB)

In the paper, a potential of solar energy for drying of medicinal plants in Polish conditions is estimated and development of solar drying technologies is presented. The results of economic assessment of flat-plate solar collectors applied for drying of medicinal plants on a farm are promising. In some specific conditions, e.g. drying of wild grown medicinal plants in remote areas, even application of photovoltaic modules for driving of a fan of a solar dryer is a profitable option and enables easy control of the drying air temperature.

1997-10-01

460

Differential decay of parent-of-origin-specific genomic sharing in cystic fibrosis-affected sib pairs maps a paternally imprinted locus to 7q34  

UK PubMed Central (United Kingdom)

Cystic fibrosis (CF) is a monogenic disease characterized by a high variability of disease severity and outcome that points to the role of environmental factors and modulating genes that shape the course...Full Text Available

2010-05-01

461

Dietary effects on body composition, glucose metabolism, and longevity are modulated by skeletal muscle mitochondrial uncoupling in mice  

UK PubMed Central (United Kingdom)

Little is known about how diet and energy metabolism interact in determination of lifespan under ad libitum feeding. From 12 weeks of age until death, male and female wild-type (WT) and transgenic (TG)...Full Text Available

2011-02-01

462

Development of solar agricultural dryers combined with PV modules and solar collectors  

Energy Technology Data Exchange (ETDEWEB)

The intention of the research carried out was to develop photovoltaic driven solar heating systems applied for drying of medicinal plants in remote areas. Identification of hybrid photovoltaic - photothermal systems was done and discussion of technical features and applicability of such systems in agriculture is presented. Detail technical specification of PV powered medicinal plants solar dryer and cost effectiveness parameters are given. Operational and economic results obtained during testing of the dryer are promising. (orig.) 4 refs.

1997-12-31

463

Development of a solution method for the differential equations arising in the biosphere module of the BNFL's suite of codes MONDRIAN  

International Nuclear Information System (INIS)

British Nuclear Fuels plc owns and operates the near-surface Drigg disposal facility for low level radioactive waste. The long-term performance of the site is modelled by a suite of computer codes called MONDRIAN. One of the modules of MONDRIAN deals with the transport of radionuclides through the environment, and this paper reports on the current status of this module (BIOS). We derive the basic set of working equations from first principles and show clearly how the approximate nature of the final equations is arrived at. This is done by an averaging process leading to compartments, in and out of which radionuclides, solids and water can flow. The equations allow radioactive decay chains and an arbitrary number of compartments. There is also the facility to deal with changes in the rate coefficients, thereby simulating different environmental states. It is also possible to include the creation of new compartments arising as a consequence of ...

2002-06-01

464

Designing Human m1 Muscarinic Receptor-Targeted Hydrophobic Eigenmode Matched Peptides as Functional Modulators  

UK PubMed Central (United Kingdom)

A new proprietary de novo peptide design technique generated ten 15-residue peptides targeting and containing the leading nontransmembrane hydrophobic autocorrelation wavelengths, “modes”,...Full Text Available

2004-03-01

465

Design and performance of radioisotope space power systems based on OSC multitube AMTEC converter designs  

Energy Technology Data Exchange (ETDEWEB)

This paper extends the analytical procedure described in another paper in these proceedings to analyze a variety of compact and light-weight OSC-designed radioisotope-heated generators. Those generators employed General Purpose Heat Source (GPHS) modules and a converter containing sixteen AMTEC cells of OSC`s revised five-tube design with enhanced cell wall reflectivity described in a companion paper in these proceedings. OSC found that the performance of the generator is primarily a function of the thermal insulation between the outside of the generator`s 16 cells and the inside of its wall. After examining a variety of insulation options, it was found that the generator`s performance is optimized by employing a hybrid insulation system, in which the space between the cells is filled with fibrous Min-K insulation, and the generator walls are lined with tapered (i.e., graded-length) multifoil insulation. The OSC design results in a very compact generator, with ...

1997-12-31

466

Decreased 7,12-dimethylbenz[a]anthracene-induced carcinogenesis coincides with the induction of antitumor immunities in adult female B6C3F1 mice pretreated with genistein  

UK PubMed Central (United Kingdom)

The objective of this study was to determine if genistein (GEN) modulation of the immune responses might contribute to the increased host resistances to tumors. A time-course study was performed...Full Text Available

2007-12-01

467

Comparative study of convolution, superposition, and fast superposition algorithms in conventional radiotherapy, three-dimensional conformal radiotherapy, and intensity modulated radiotherapy techniques for various sites, done on CMS XIO planning system  

UK PubMed Central (United Kingdom)

The aim of this study is to compare the dosimetry results that are obtained by using Convolution, Superposition and Fast Superposition algorithms in Conventional Radiotherapy, Three-Dimensional Conformal...Full Text Available

2009-01-01

468

Circadian and circatrigintan respiratory and related intermodulations in the crab Barytelphusa guerini.  

Science.gov (United States)

Respiration and related physiologic variables in different tissues of Barytelphusa guerini and the respiration of this freshwater crab as a whole are closely synchronized in phase and in frequency along the circadian scale, in the face of large differences in circadian amplitude. A very close timing of most of the 36 variables examined in 2 separate circadian profiles and a modulation of some of these variables in added profiles as a function of lunar stage are clearly demonstrable, statistically significant and illustrative of time relations at 2 interacting frequencies. PMID:6745009

469

CAPSULE REPORT: BAHCO FLUE GAS DESULFURIZATION AND PARTICULATE REMOVAL SYSTEM  

Science.gov (United States)

This capsule report describes a Research-Cottrell/Bahco scrubber module for sulfur dioxide and particulate emission control located at the central heat plant of Rickenbacker Air Force Base. he report also describes flue gas desulfurization technology using any fuel, including hig...

470

Alterations in Adenylate Kinase Activity in Human PBMCs after In Vitro Exposure to Electromagnetic Field: Comparison between Extremely Low Frequency Electromagnetic Field (ELF) and Therapeutic Application of a Musically Modulated Electromagnetic Field (TAMMEF)  

UK PubMed Central (United Kingdom)

This study investigated the effects of electromagnetic fields on enzymes involved in purine metabolism in human peripheral blood mononuclear cells in vitro. Cells were obtained from 20 volunteers. We...Full Text Available

2009-01-01

471

ARSENIC TRIOXIDE INDUCES A BECLIN-1 INDEPENDENT AUTOPHAGIC PATHWAY VIA MODULATION OF SNON/SKIL EXPRESSION IN OVARIAN CARCINOMA CELLS  

UK PubMed Central (United Kingdom)

Arsenic trioxide (As2O3), used to treat promyelocytic leukemia, triggers cell death via unknown mechanisms. To further our understanding of As2O3-induced...Full Text Available

2010-12-01

472

A simple and continuous on-state current model of polysilicon thin-film transistors for circuit simulation  

Energy Technology Data Exchange (ETDEWEB)

A simple and continuous model for the on-state current of polysilicon thin-film transistors, suitable for implementation in circuit simulators, is presented. The model includes the potential barrier at the grain boundaries, the channel length modulation and the excess current due to impact ionization. Comparison between measured output characteristics and the model shows excellent agreement over wide range of bias voltages and for devices with different gate lengths.

2005-01-01

473

A Genetic Screen for Ribosomal DNA Silencing Defects Identifies Multiple DNA Replication and Chromatin-Modulating Factors  

UK PubMed Central (United Kingdom)

Transcriptional silencing in Saccharomyces cerevisiae occurs at several genetic loci, including the ribosomal DNA (rDNA). Silencing at telomeres (telomere position effect [TPE])...Full Text Available

1999-04-01

474

Thermal spraying of reactive materials to form wear-resistant composite coatings  

Energy Technology Data Exchange (ETDEWEB)

The dispersion of more than 20 vol pct submicrometer ceramic particles within a metallic matrix and the deposition of such a cermet to form a thick and tough coating presents problems. Most of the coating techniques have failed in attempting to homogeneously disperse very fine and hard particles in large amounts while avoiding their decomposition or reaction with the metal matrix during the deposition process. A simple and efficient method has been developed for producing ceramic-containing composite coatings. It consists in synthesizing cermet-based materials and in depositing them by a rapid solidification process, such as thermal spraying. Boride- and carbide-based materials have been successfully obtained by plasma spraying reactive powders comprising the basic reagents. These materials, with a microstructure of submicrometer ceramic particles dispersed in a metallic matrix, exhibit good wear-resistant properties (abrasion and sliding wear). Finally, reactive core wire arc spraying ...

1992-03-01

475

Theoretical approach to initial growth kinetics of GaN on GaN(001)  

British Library Electronic Table of Contents (United Kingdom)

We carried out theoretical analyses based on ab initio calculations incorporates in which free energy of the vapor phase is incorporated in order to determine the initial growth kinetics of c-GaN on GaN(001)-(4x1). The feasibility of the theoretical approach had been confirmed by calculations of Ga adsorption-desorption transition temperature and transition beam equivalent pressures on the GaAs(001)-(4x2)b2 surface in our previous work [Y. Kangawa, T. Ito, A. Taguchi, K. Shiraishi, T. Ohachi, Surf. Sci. 493 (2001) 178]. The results of calculations suggest that no Ga adsorption occurs on the initial surface under typical growth conditions but that a Ga adsorption site appears after N adsorption on GaN(001)-(4x1). That is, in the initial growth stage of c-GaN on GaN(001)-(4x1), a N-adsorbed ...

2007-01-01

476

Structural studies of some phospho-borate glasses using ultrasonic pulse-echo technique, DSC and IR spectroscopy  

International Nuclear Information System (INIS)

Glasses in the system (95-x) [0.25 Na2O-0.75 B2O3]-x P2O5-5 Fe2O3 (0?x?15 mol%), have been prepared by the melt quenching technique. Elastic properties and FT-IR spectroscopic studies have been employed to study the role of P2O5 on the structure of the glass system. Elastic properties Poisson's ratio, micro-hardness and Debye temperature have been investigated using sound wave velocity measurements at 4 MHz (both longitudinal and shear) at room temperature. The results showed that the density and the molar volume increase as both sound velocities and the determined glass transition temperatures decrease with increasing the contents of P2O5. Infrared spectra of the glasses reveal that the borate network consists of diborate units and is affected by the increase in the concentration of P2O5 content as a second network former. These results are interpreted in terms of the replacement of the diborate units with B-O-B bridges by phosphate units with ...

2009-06-01

477

Spark plasma sintered tantalum carbide: Effect of pressure and nano-boron carbide addition on microstructure and mechanical properties  

British Library Electronic Table of Contents (United Kingdom)

TaC and TaC-1wt.% B4C powders were consolidated using spark plasma sintering (SPS) at 1850^oC and varying pressure of 100, 255 and 363MPa. The effect of pressure on the densification and grain size is evaluated. The role of nano-sized B4C as sintering aid and grain growth inhibitor is studied by means of XRD, SEM and high resolution TEM. Fully dense TaC samples were produced at a pressure of 255MPa and higher at 1850^oC. The increasing pressure also resulted in an increase in TaC grain size. Addition of B4C leads to an increase in the density of 100MPa sample from 89% to 97%. B4C nano-powder resists grain growth even at high pressure of 363MPa. The formation of TaB2/Carbon at TaC grain boundaries helps in pinning the grain boundary and inhibiting grain growth. The effect of B4C addition on...

2011-01-01

478

Principe local-global pour les z\\'ero-cycles sur certaines fibrations au-dessus d'une courbe: II  

CERN Document Server

We consider an admissible fibration $\\pi:X\\to\\mathbb{P}^1$ over a curve over a number field, of which the generic fiber $X_\\eta$ is geometrically rationally connected. We suppose that there exists a generalized Hilbertian subset $\\textsf{Hil}$ of $\\mathbb{P}^1$, such that the Brauer-Manin obstruction is the only obstruction to the Hasse principle (resp. to the weak approximation) for $X_\\theta(\\theta\\in \\textsf{Hil}).$ We prove that the Brauer-Manin obstruction is the only obstruction to the Hasse principle (resp. to the strong approximation) for zero-cycles of degree 1 on $X$ in the following cases: $(B_1)$ the index of the generic fibre $X_\\eta$ is equal to 1; $(B_2)$ all fibers are geometrically integral. Then, we obtain some similar results for certain fibrations over $\\mathbb{P}^n$. As a consequence, we obtain the following result: let $X$ be a smooth projective geometrically rationally connected variety over a number field ...

2010-01-01

479

On the band gap dependence of refractive indices of some quaternary III-V and II-VI compounds of device interest  

International Nuclear Information System (INIS)

The credibility of the model proposed by Ghosh in predicting the refractive indices of mixed semiconductor crystals of technological importance within their miscibility range as a function of band gap is demonstrated. The high-frequency refractive indices of four quaternary alloys Al_xGa_1_-_x_-_yIn_yP (y = 0.49, 0 #<=# x #<=# 0.51), InSb_xAs_1_-_x_-_yP_y (y = 2.2x, 0 #<=# x #<=# 0.313, 0 #<=# y #<=# 0.638), Cd_xZn_1_-_x_-_yHg_ySe (x + y = 1, 0.153 #<=# x #<=# 0.684, 0.316 #<=# y #<=# 0.847), and CdS_1_-_x_-_ySe_xTe_y (x + y = 1, 0.15 #<=# x #<=# 0.93, 0.07 #<=# y #<=# 0.85) are calculated according to the relation n"2-1 = A/(E_g + B)"2 where A is an energy gap dependent constant and B is a constant depending on crystal ionicity. The calculated values show excellent agreement with the experimental data thus justifying the validity of the model.

480

Magnetic properties of Pr_2PdSi_3 single crystals  

International Nuclear Information System (INIS)

Ternary R_2TSi_3 intermetallic compounds (R=Rare Earth, T=Transition Metal) with hexagonal AlB_2-type crystallographic structure are known because of their interesting physical properties. Pr_2PdSi_3 single crystals were grown by a vertical floating zone method. The compound exhibits congruent melting behavior at a liquidus temperature of about 1770 C. Single crystalline samples show a huge anisotropy at low temperatures due to the crystal electric field effect and order antiferromagnetically below the Neel temperature T_N=2.17 K. This value approximately obeys the linear de Gennes scaling for this class of compounds. The [001] orientation was identified as the magnetic easy axis at room temperature. At lower temperature (#approx#20 K) magnetic easy and hard axes interchange with each other. Two additional magnetic phase transitions were observed at temperatures below 1 K.

2010-03-21

481

Lysozyme dimer formation on lysozyme oxidation with B./2 as studied by fluorescence evolution  

International Nuclear Information System (INIS)

Lysozyme dimers produced on oxidation of lysozyme with Br_2anion radicals in aqueous solutions exhibit a fluorescence spectrum (lambdasub(max) = 400 nm) closely similar to that of bi-tyrosine. This suggests that the dimer is likely to have a tyrosine-tyrosine bond resulting from the combination of tyrosine phenoxy radicals of two lysozyme molecules. Kinetic studies on dimer formation were made by measuring time-dependent fluorescence after pulsed-electron irradiation over wide pH range. The results lead to the following conclusions. The second-order growth of the dimer fluorescence observed at pH 10.7-12.5 reflects the combination process of the lysozyme radicals, which is rate-determining in the pH range. On the other hand, the first-order growth observed at pH 6.8-10.2 is attributable to the enolization of the keto-form of the dimer. A tentative reaction scheme is proposed for the dimer formation. (author).

482

Is nest-drifting behaviour an insurance policy for maximising indirect fitness in primitively eusocial paper wasps?  

Environmental Research Database

ObjectivesThe main objectives of this project are: 1. To determine whether nest-drifting behaviour allows helpers to maximise their indirect fitness in the paper wasp Polistes canadensis. Specifically, I will test a) whether nest-drifters apportion helping effort in relation to the productivity benefits of different nests (hypothesis 1a), and b) whether nest-drifters can adjust their investment in response to changes in the productivity payoffs of different nests (hypothesis 1b). 2. To determine [continued...]DescriptionDarwin's theory of natural selection predicts that organisms should act selfishly in order to pass on as many of their genes to the next generation as possible. The evolution of social behaviour is a paradox because it requires that some individuals forgo reproduction in order to help raise the offspring of others. Explaining the evolution of helping behaviour in animal societies has been a major focus for evolutionary ...

2011-01-20

483

Glass-ceramic sealants for solid oxide fuel cells: Part I. Physical properties  

International Nuclear Information System (INIS)

A family of sealant materials has been developed for use in the solid oxide fuel cell (SOFC) and in other applications in the temperature range of 800 endash 1000 degree C. These materials are based on glasses and glass-ceramics in the SrO endash La_2O_3 endash Al_2O_3 endash B_2O_3 endash SiO_2 system. The coefficients of thermal expansion (CTE) for these materials are in the range of 8 endash 13x10"-"6/degree C, a good match with those of the SOFC components. These sealant materials bond well with the ceramics of the SOFC and, more importantly, form bonds that can be thermally cycled without failure. At the fuel cell operating temperature, the sealants have viscosities in the range of 10"4-10"6 Pa-s, which allow them to tolerate a CTE mismatch of about 20% among the bonded substrates. The gas tightness of a sample seal was demonstrated in a simple zirconia-based oxygen concentration cell. copyright 1996 Materials Research Society.

484

Genetic organization of Bungarus multicinctus protease inhibitor-like proteins.  

Science.gov (United States)

The structural organization of the genes encoding Bungarus multicinctus protease inhibitor-like proteins (PILPs), PILP-1, PILP-2 and PILP-3, are reported in this study. Unlike PILP-2 and PILP-3, recombinant PILP-1 exhibited inhibitory activity on trypsin. PILP genes and B chain genes shared identical organization with three exons interrupted by two introns in similar positions. On the contrary, intron 1 of these genes had a similar size, a notable variation with the size of intron 2 was observed. It was found that two regions at the second intron of B1 chain and B2 chain genes were absent in that of PILP genes. Noticeably, intronic insertion in the second intron of B chain genes appeared in the promoter region of PILP-1 gene, but not in that of PILP-2 and PILP-3 genes. Comparative analyses of PILP genes and B chain genes showed that the protein-coding regions of the exons are more diverse than introns, except for in the signal peptide domain. ...

2008-03-27

485

Elastic properties and structural studies on some zinc-borate glasses derived from ultrasonic, FT-IR and X-ray techniques  

International Nuclear Information System (INIS)

Glasses in the system (1 - x) [29Na2O- 4Al2O3- 67B2O3]- xZnO (0 ? x ? 35 mol%), have been prepared by the melt quenching technique. Elastic properties, X-ray and FT-IR spectroscopic studies have been employed to study the role of ZnO on the structure of the investigated glass system. Elastic properties and Debye temperature have been investigated using sound wave velocity measurements at 4 MHz at room temperature. The results showed that the density increases and the molar volume decreases while both sound velocities and the determined glass transition temperatures decrease with increase in x. X-ray and infrared spectra of the glasses reveal that the borate network consists of diborate units and is affected by the increase in the concentration of ZnO content. These results are interpreted in terms of the decrease in the N4 values (fraction of tetrahedral coordinated boron atoms), and substitution of longer bond lengths of Zn-O in place of ...

2009-05-05

486

Effect of heat transfer augmentation by square rod array in impinging air jet system(heat transfer characteristic of potential core region)  

Energy Technology Data Exchange (ETDEWEB)

This research has been proceeded over the potential core region (H/B=2) of two-dimensional impinging air jet system, in which square rods(width of 6 mm) has been set up in front of heating surface in order to increase heat transfer. The objective of this research was to investigate the characteristics of heat transfer and air flow, in cases of the clearance from rods to heating surface (C = 1, 2, 4, 6 mm) and the pitch between each rods(P = 30, 40, 50 mm) changed. And this research compared the above with the experimentation without rods. As result, heat transfer performance was best under the condition of C = 1 mm, in case clearance changed, and there was no serious difference in the effect of heat transfer augmentation in the case of pitch of rods changed. (author) 11 refs. 12 figs.

1995-07-01

487

Alternate alloying for environmental resistance; Proceedings of the Symposium, New Orleans, LA, Mar. 2-6, 1986  

Energy Technology Data Exchange (ETDEWEB)

Papers are presented on the development of oxidation- and sulfidation-resistant ferritic alloys; the microstructural stability of sulfidation-resistant FeCrAl stainless steels around 500 C; age hardening in Fe-Mn-Al-C austenitic alloys; the oxidation/corrosion behavior of low-Cr Fe-Cr-Ni alloys containing Zr or Nb; the high temperature oxidation/corrosion of iron-based superalloys; and the role of Mo in the Na/sub 2/SO/sub 4/ induced corrosion of superalloys at high temperature. Topics discussed include the effect of variations of Co content on the cyclic oxidation resistance of selected Ni-base superalloys; high temperature oxidation of Fe based alloys; the morphological development of high temperature oxide scales of Fe-Mn-Al base alloys; and the oxidation of an Fe-Mn-Al-C alloy at 1000 C. Consideration is given to the corrosion properties of Fe-Mn-Al alloys; passive films formed on nonmagnetic Cr-Mn-N stainless steels in chloride containing environments; the tubo 25 nickel base ...

1987-01-01

488

Ultrashallow P"+/N junction formation by plasma ion implantation  

International Nuclear Information System (INIS)

We investigated the electrical characteristics and the junction depth of ultra-shallow junctions formed by using the plasma-doping method. Compared with ultra-low energy boron-ion implantation at 500 eV, the junctions formed with the plasma-doping process exhibited shallow junction depths and low sheet resistances. The junction depths of the plasma-doped samples were 150 A and 330 A after annealing for 10 s at 900 .deg. C and 950 .deg. C, respectively. For the same junction depth, the sheet resistance of the B_2H_6 plasma-doped sample was an order of magnitude less than that of the 500-eV B-ion implanted sample. Cross-sectional transmission electron microscopy and deep level transient spectroscopy showed that the defects formed by the B_2H_6 plasma-doping process could be removed by annealing at 950 .deg. C for 10 s. The scaling of metal-oxide-semiconductor field-effect-transistor (MOSFET) device ...

2000-12-01

489

Synthesis, crystal structure and optical properties of a novel sodium lead pentaborate, NaPbB5O9  

International Nuclear Information System (INIS)

A novel sodium lead pentaborate, NaPbB5O9, has been successfully synthesized by standard solid-state reaction. The single-crystal X-ray structural analysis showed that NaPbB5O9 crystallizes in the monoclinic space group P21/c with a=6.5324(10) A, b=13.0234(2) A, c=8.5838(10) A, ?=104.971(10)o, and Z=4. The crystal structure is composed of double ring [B5O9]3- units, [PbO7] and [NaO7] polyhedra. [B5O9]3- groups connect with each other forming two-dimensional infinite ?[B5O9]3- layers, while [PbO7] and [NaO7] polyhedra are located between the layers. [PbO7] polyhedra linked together via corner-sharing O atom forming novel infinite ?[PbO6] chains along the c axis. The thermal behavior, IR spectrum and the optical diffuse reflectance spectrum of NaPbB5O9 were reported. -- Graphical abstract: A new phase, NaPbB5O9, has been discovered in the ternary M2O-PbO-B2O3 (M=alkali-metal) system. The crystal structure consists of a novel infinite ?[PbO6] ...

2011-04-01

490

United States Geological Survey (USGS) FM cassette seismic-refraction recording system  

Energy Technology Data Exchange (ETDEWEB)

In this two chapter report, instrumentation used to collect seismic data is described. This data acquisition system has two parts: (1) portable anolog seismic recorders and related ``hand-held-testers`` (HHT) and (2) portable digitizing units. During the anolog recording process, ground motion is sensed by a 2-Hz vertical-component seismometer. The voltage output from the seismometer is split without amplification and sent to three parallel amplifier circuit boards. Each circuit board amplifiers the seismic signal in three stages and then frequency modulates the signal. Amplification at the last two stages can be set by the user. An internal precision clock signal is also frequency modulated. The three data carrier frequencies, the clock carrier frequency, and a tape-speed compensation carrier frequency are summed and recorded on a recorded on a cassette tape. During the digitizing process, the cassette tapes are played back and the signals are ...

1988-12-31

491

FY1999 Meeting of The Society of Heating, Air-Conditioning and Sanitary Engineering of Japan. Thermal simulation I; 1999 nendo gakujutsu koenkai gaiyo. Onnetsu simulation 1  

Energy Technology Data Exchange (ETDEWEB)

E-35 reported the specific air flow analysis program using a CFSV model (including a human body model) to develop a high-accuracy evaluation simulator for heterogeneous thermal environment based on human thermal physiological conditions. E-36 reported development of the radiation heat transfer analysis module by using a numerical integral method to calculate shape factors. Radiation heat transfer characteristics every body part were clarified quantitatively by this module. E-37 reported the results on continuous measurement of physiological conditions and thermal environment factors every monitor under controlled indoor thermal environment, to collect measurement data necessary for improving the accuracy of a prediction program for human body temperatures. E-38 reported the study result on physiological reaction and subjective evaluation through an examinee experiment in a blood controlled region, to collect basic data for the above ...

1999-12-05

492

Donut-shaped high-dose configuration for proton beam radiation therapy  

Energy Technology Data Exchange (ETDEWEB)

Background: the authors report on the conception and first clinical application of a donut-shaped high-dose configuration for proton therapy (PT). This approach allows one to intensify target volume dose coverage for targets encompassing a critical, dose-limiting structure - like here, the cauda equina -, whilst delivering minimal dose to other healthy structures surrounding the target, thereby reducing the integral dose. Methods and results: intensity-modulated PT methods (IMPT) for spot scanning were applied to create and deliver a donut-shaped high-dose configuration with protons, allowing treating > 75% of the target with at least 95% of the prescribed dose of 72.8 CGE, whilst restricting dose to the cauda equina to 60-65 CGE. Integral dose was lower by a factor of 3.3 as compared to intensity-modulated radiotherapy with photons (IMXT). Conclusion: IMPT and spot scanning technology allow a potentially clinically useful approach which ...

2005-01-01

493

Donut-shaped high-dose configuration for proton beam radiation therapy  

International Nuclear Information System (INIS)

Background: the authors report on the conception and first clinical application of a donut-shaped high-dose configuration for proton therapy (PT). This approach allows one to intensify target volume dose coverage for targets encompassing a critical, dose-limiting structure - like here, the cauda equina -, whilst delivering minimal dose to other healthy structures surrounding the target, thereby reducing the integral dose. Methods and results: intensity-modulated PT methods (IMPT) for spot scanning were applied to create and deliver a donut-shaped high-dose configuration with protons, allowing treating > 75% of the target with at least 95% of the prescribed dose of 72.8 CGE, whilst restricting dose to the cauda equina to 60-65 CGE. Integral dose was lower by a factor of 3.3 as compared to intensity-modulated radiotherapy with photons (IMXT). Conclusion: IMPT and spot scanning technology allow a potentially clinically useful approach which is ...

2005-01-01

494

Compact Dielectric Wall Accelerator Development For Intensity Modulated Proton Therapy And Homeland Security Applications  

Energy Technology Data Exchange (ETDEWEB)

Compact dielectric wall (DWA) accelerator technology is being developed at the Lawrence Livermore National Laboratory. The DWA accelerator uses fast switched high voltage transmission lines to generate pulsed electric fields on the inside of a high gradient insulating (HGI) acceleration tube. Its high electric field gradients are achieved by the use of alternating insulators and conductors and short pulse times. The DWA concept can be applied to accelerate charge particle beams with any charge to mass ratio and energy. Based on the DWA system, a novel compact proton therapy accelerator is being developed. This proton therapy system will produce individual pulses that can be varied in intensity, energy and spot width. The system will be capable of being sited in a conventional linac vault and provide intensity modulated rotational therapy. The status of the developmental new technologies that make the compact system possible will be reviewed. These include, high ...

2009-06-17

495

Calibration of the modulation transfer function of surface profilometers with binary pseudo-random test standards: expanding the application range  

Energy Technology Data Exchange (ETDEWEB)

A modulation transfer function (MTF) calibration method based on binary pseudo-random (BPR) gratings and arrays [Proc. SPIE 7077-7 (2007), Opt. Eng. 47, 073602 (2008)] has been proven to be an effective MTF calibration method for a number of interferometric microscopes and a scatterometer [Nucl. Instr. and Meth. A616, 172 (2010)]. Here we report on a further expansion of the application range of the method. We describe the MTF calibration of a 6 inch phase shifting Fizeau interferometer. Beyond providing a direct measurement of the interferometer's MTF, tests with a BPR array surface have revealed an asymmetry in the instrument's data processing algorithm that fundamentally limits its bandwidth. Moreover, the tests have illustrated the effects of the instrument's detrending and filtering procedures on power spectral density measurements. The details of the development of a BPR test sample suitable for calibration of scanning and ...

2011-03-14

496

Calibration of the modulation transfer function of surface profilometers with binary pseudo-random test standards: Expanding the application range  

Energy Technology Data Exchange (ETDEWEB)

A modulation transfer function (MTF) calibration method based on binary pseudo-random (BPR) gratings and arrays [Proc. SPIE 7077-7 (2007), Opt. Eng. 47(7), 073602-1-5 (2008)] has been proven to be an effective MTF calibration method for a number of interferometric microscopes and a scatterometer [Nucl. Instr. and Meth. A 616, 172-82 (2010]. Here we report on a significant expansion of the application range of the method. We describe the MTF calibration of a 6 inch phase shifting Fizeau interferometer. Beyond providing a direct measurement of the interferometer's MTF, tests with a BPR array surface have revealed an asymmetry in the instrument's data processing algorithm that fundamentally limits its bandwidth. Moreover, the tests have illustrated the effects of the instrument's detrending and filtering procedures on power spectral density measurements. The details of the development of a BPR test sample suitable for calibration of scanning ...

2010-07-26

497

Binary pseudo-random gratings and arrays for calibration of the modulation transfer function of surface profilometers: recent developments  

Energy Technology Data Exchange (ETDEWEB)

The major problem of measurement of a power spectral density (PSD) distribution of the surface heights with surface profilometers arises due to the unknown Modulation Transfer Function (MTF) of the instruments. The MTF tends to distort the PSD at higher spatial frequencies. It has been suggested [Proc. SPIE 7077-7, (2007), Opt. Eng. 47 (7), 073602-1-5 (2008)] that the instrumental MTF of a surface profiler can be precisely measured using standard test surfaces based on binary pseudo-random (BPR) patterns. In the cited work, a one dimensional (1D) realization of the suggested method based on use of BPR gratings has been demonstrated. Here, we present recent achievements made in fabricating and using two-dimensional (2D) BPR arrays that allow for a direct 2D calibration of the instrumental MTF. The 2D BPRAs were used as standard test surfaces for 2D MTF calibration of the MicromapTM-570 interferometric microscope with all available objectives. The effects of ...

2009-07-07

498

BINERY PSEUDO-RANDOM GRATING AS A STANDARD TEST SURFACE FOR MEASUREMENT OF MODULATION TRANSFER FUNCTION OF INTERFEROMETRIC MICROSCOPES.  

Energy Technology Data Exchange (ETDEWEB)

The task of designing high performance X-ray optical systems requires the development of sophisticated X-ray scattering calculations based on rigorous information about the optics. One of the most insightful approaches to these calculations is based on the power spectral density (PSD) distribution of the surface height. The major problem of measurement of a PSD distribution with an interferometric and/or atomic force microscope arises due to the unknown Modulation Transfer Function (MTF) of the instruments. The MTF characterizes the perturbation of the PSD distribution at higher spatial frequencies. Here, we describe a new method and dedicated test surfaces for calibration of the MTF of a microscope. The method is based on use of a specially designed Binary Pseudo-random (BPR) grating. Comparison of a theoretically calculated PSD spectrum of a BPR grating with a spectrum measured with the grating provides the desired calibration of the instrumental MTF. The ...

2007-08-01

499

A Compact Linac for Proton Therapy Based on a Dielectric Wall Accelerator  

Energy Technology Data Exchange (ETDEWEB)

A novel compact CT-guided intensity modulated proton radiotherapy (IMPT) system is described. The system is being designed to deliver fast IMPT so that larger target volumes and motion management can be accomplished. The system will be ideal for large and complex target volumes in young patients. The basis of the design is the dielectric wall accelerator (DWA) system being developed at the Lawrence Livermore National Laboratory (LLNL). The DWA uses fast switched high voltage transmission lines to generate pulsed electric fields on the inside of a high gradient insulating (HGI) acceleration tube. High electric field gradients are achieved by the use of alternating insulators and conductors and short pulse times. The system will produce individual pulses that can be varied in intensity, energy and spot width. The IMPT planning system will optimize delivery characteristics. The system will be capable of being sited in a conventional linac vault and provide intensity ...

2007-10-29