Sample records for association

  1. Hunting association

    Marval, Miroslav


    Czech hunting has come during its existence through substantial changes dependent on the political development in the country. Hunting as we know it presently has evolved since 1993 when hunting districts started to be leased to hunting associations as well as to individuals or companies. This is one of the reasons why hunting districts in the Czech Republic are most often used by hunting associations. These associations are founded by members on the ground of articles written with regard to ...

  2. Staff Association

    Staff Association


    Remove of the staff association office   The Staff Association offices are going to be renovated during the coming four months, February to May 2014. The physical move from our current premises 64/R-002 to our temporary office in  510/R-010 will take place on Friday January 31st, so the Secretariat will be closed on that day. Hence, from Monday February 3rd until the end of May 2014 the Staff Association Secretariat will be located in 510/R-010 (entrance just across the CERN Printshop).    

  3. Alzheimer's Association

    ... will not share your information. * Required. View archives. Alzheimer's impact is growing Alzheimer's disease is the sixth- ... Last Updated: Our vision is a world without Alzheimer's Formed in 1980, the Alzheimer's Association advances research ...

  4. CHARGE Association

    Semanti Chakraborty


    Full Text Available We present here a case of 17-year-old boy from Kolkata presenting with obesity, bilateral gynecomastia, mental retardation, and hypogonadotrophic hypogonadism. The patient weighed 70 kg and was of 153 cm height. Facial asymmetry (unilateral facial palsy, gynecomastia, decreased pubic and axillary hair, small penis, decreased right testicular volume, non-palpable left testis, and right-sided congenital inguinal hernia was present. The patient also had disc coloboma, convergent squint, microcornea, microphthalmia, pseudohypertelorism, low set ears, short neck, and choanalatresia. He had h/o VSD repaired with patch. Laboratory examination revealed haemoglobin 9.9 mg/dl, urea 24 mg/dl, creatinine 0.68 mg/dl. IGF1 77.80 ng/ml (decreased for age, GH <0.05 ng/ml, testosterone 0.25 ng/ml, FSH-0.95 ΅IU/ml, LH 0.60 ΅IU/ml. ACTH, 8:00 A.M cortisol, FT3, FT4, TSH, estradiol, DHEA-S, lipid profile, and LFT was within normal limits. Prolactin was elevated at 38.50 ng/ml. The patient′s karyotype was 46XY. Echocardiography revealed ventricularseptal defect closed with patch, grade 1 aortic regurgitation, and ejection fraction 67%. Ultrasound testis showed small right testis within scrotal sac and undescended left testis within left inguinal canal. CT scan paranasal sinuses revealed choanalatresia and deviation of nasal septum to the right. Sonomammography revealed bilateral proliferation of fibroglandular elements predominantly in subareoalar region of breasts. MRI of brain and pituitary region revealed markedly atrophic pituitary gland parenchyma with preserved infundibulum and hypothalamus and widened suprasellar cistern. The CHARGE association is an increasingly recognized non-random pattern of congenital anomalies comprising of coloboma, heart defect, choanal atresia, retarded growth and development, genital hypoplasia, ear abnormalities, and/or deafness. [1] These anomalies have a higher probability of occurring together. In this report, we have

  5. IC Associated Conditions

    ... Intimacy & IC Support for Men Children & IC La Cistitis Intersticial IC in Other Languages Associated Conditions Allergies and ... Intimacy & IC Support for Men Children & IC La Cistitis Intersticial IC in Other Languages Associated Conditions Allergies and ...

  6. Associated Health Allocation

    Department of Veterans Affairs — The Associated Health Allocation Database is used to determine the allocation of positions and funds for VA Associated Health programs offered by Veterans Affairs...

  7. Intended Brand Associations

    Koll, Oliver; von Wallpach, Sylvia


    (attitudinal and behavioral). The results show that consumers with high brand association match show more positive brand response. However, after accounting for the valence of associations match does not add explanatory power. This outcome challenges a key foundation of brand management. The discussion......Brand managers exhibit considerable effort to define intended brand associations to anchor in consumers' minds. They follow a credo deeply rooted in branding literature: intended brand associations drive consumer response and brand equity. This article investigates the benefits of a strong overlap...... of actual consumer brand associations and management-intended brand associations (brand association match). The article presents results from two large-scale studies (3353 and 1201 respondents) involving one consumer goods and one service brand with multiple operationalizations of consumer response...

  8. Italian library associations

    Ksenija Petaros-Kmetec


    Full Text Available In Italy, five library associations of national significance function at present. There are special associations of ecclesiastic libraries, prison libraries, architecture libraries and libraries with artistic material. The role of the general national association, covering all types of libraries including documentation centres, is played by the Italian Library Association. It strive for the development of a contemporary Italian library system comparable to international standards, monitors library legislation, promotes education for librarians and keeps the librarians and the broader public informed about the importance of libraries and librarianship for society. The activity and efforts of the association are reflected through their website offering much information and links to similar sites. ILA presents and realises its activities for both, the librarians and the public users. A great deal of actions promoting libraries and the Library Association might be interesting for Slovenia and perhaps transferred to our environment.

  9. Associative Analysis in Statistics

    Mihaela Muntean


    Full Text Available In the last years, the interest in technologies such as in-memory analytics and associative search has increased. This paper explores how you can use in-memory analytics and an associative model in statistics. The word “associative” puts the emphasis on understanding how datasets relate to one another. The paper presents the main characteristics of “associative” data model. Also, the paper presents how to design an associative model for labor market indicators analysis. The source is the EU Labor Force Survey. Also, this paper presents how to make associative analysis.

  10. American College Health Association

    ... Dollars at Work Recognizing Donors Find us on social media! Home Contact Us Marketplace Cart Copyright © 2016 American College Health Association | Privacy and Usage Policies | Spokesperson and ...

  11. Today's Associations, Tomorrow's Unions.

    Ichniowski, Casey; Zax, Jeffrey S.


    Analysis of census data on local government departments investigated the effects of association-style unionism on union membership. Found that in all local government services, the presence of an association in 1977 was a strong predictor of the formation of a bargaining unit by 1982--holding constant other important determinants of public…

  12. Neuroscience: Incepting Associations.

    deBettencourt, Megan T; Norman, Kenneth A


    A recent study has used real-time fMRI neurofeedback to induce color-specific activity patterns in early visual cortex as participants viewed achromatic gratings. This procedure resulted in an association between the color and the displayed grating orientation, suggesting that early visual cortex can support associative learning of this type. PMID:27458913

  13. Civic Engagement and Associationalism

    Alexander, Damon Timothy; Barraket, Jo; Lewis, Jenny;


    The relationship between participation in civic and political activities and membership of voluntary associations is now well established. What is less clear is the relative impacts of how much time people spend on group activities (associational intensity), and the number and type of groups...... forms have the same impact....

  14. Graphs: Associated Markov Chains

    Murthy, Garimella Rama


    In this research paper, weighted / unweighted, directed / undirected graphs are associated with interesting Discrete Time Markov Chains (DTMCs) as well as Continuous Time Markov Chains (CTMCs). The equilibrium / transient behaviour of such Markov chains is studied. Also entropy dynamics (Shannon entropy) of certain structured Markov chains is investigated. Finally certain structured graphs and the associated Markov chains are studied.

  15. Migraine Associated Vertigo

    Cha, Yoon-Hee (Laureate Institute for Brain Research); Baloh, Robert W.


    The interrelations of migraine and vertigo are complex, eluding a simple localization either centrally or peripherally. Spontaneous episodic vertigo, benign paroxysmal positional vertigo, and Meniere's disease all occur more frequently in patients with migraine than in those without. Family studies support a hereditary predisposition to migraine associated vertigo. In this review, we discuss definitions, epidemiology, associated syndromes, neurootological abnormalities, genetics and treatment...

  16. Network Consistent Data Association.

    Chakraborty, Anirban; Das, Abir; Roy-Chowdhury, Amit K


    Existing data association techniques mostly focus on matching pairs of data-point sets and then repeating this process along space-time to achieve long term correspondences. However, in many problems such as person re-identification, a set of data-points may be observed at multiple spatio-temporal locations and/or by multiple agents in a network and simply combining the local pairwise association results between sets of data-points often leads to inconsistencies over the global space-time horizons. In this paper, we propose a Novel Network Consistent Data Association (NCDA) framework formulated as an optimization problem that not only maintains consistency in association results across the network, but also improves the pairwise data association accuracies. The proposed NCDA can be solved as a binary integer program leading to a globally optimal solution and is capable of handling the challenging data-association scenario where the number of data-points varies across different sets of instances in the network. We also present an online implementation of NCDA method that can dynamically associate new observations to already observed data-points in an iterative fashion, while maintaining network consistency. We have tested both the batch and the online NCDA in two application areas-person re-identification and spatio-temporal cell tracking and observed consistent and highly accurate data association results in all the cases. PMID:26485472

  17. Employers' Gas Association (ZPZ)

    Employers' Gas Association (ZPZ) is the institution which main task is to maintain the optimum conditions for dynamic development of its members' activities, their business activities and to maintain the common or individual interests o fits members. To meet this objective, the association: - maintains the interests of association members during discussions with representative authorities, central state administration bodies and the trade unions regarding the economic and social policy and the questions which are to be the subject matter of collective bargaining, conclusion of contracts and the collective agreements of higher force; - is the member of enterprising, negotiating and advisory authorities; - coordinates the procedure and promotes the common interests of its members in relation to the representative authorities and the central state administration bodies, central trade union authorities and in relation to the international organisation of employers and the International Labour Organisation; maintains the commercial and business activities of the members of association; submits the proposals, filling with the courts and makes interventions regarding the preparation of economic and political decisions on the national and international level; engages with the legal entities in the Slovak Republic and enters the foreign international organisations. ZPZ, originally Gas Association (PZ), was founded by the General Assembly on 27th January 1995. It was registered in compliance with the Act No. 83/1990 Coll. on Association of Citizens as amended by the act No. 300/90 Coll., as the organisation of employers with the legal personality. The Employer's Gas Association was a member of the Employers' Associations in Slovak Republic till 31st March 2004, after this date it is represented by the Republican Union of Employers in SR (RUZ SR), which was established to maintain employer's associations interests on more qualitative level. The list of members

  18. Associative Analysis in Statistics

    Mihaela Muntean


    In the last years, the interest in technologies such as in-memory analytics and associative search has increased. This paper explores how you can use in-memory analytics and an associative model in statistics. The word “associative” puts the emphasis on understanding how datasets relate to one another. The paper presents the main characteristics of “associative” data model. Also, the paper presents how to design an associative model for labor market indicators analysis. The source is the EU L...

  19. Syndicats et associations

    Bars, Loïc Le; Barthélémy, Martine; Bellanger, Emmanuel; Béroud, Sophie; Béthouart, Bruno; Boussion, Samuel; Brodiez, Axelle; Brouster, Pascale Le; Capdevielle, Jacques; Chatriot, Alain; Coffin, Jean-Christophe; Diebolt, Évelyne; Dreyfus, Michel; Faniel, Jean; Frajerman, Laurent


    Les syndicats sont et demeurent des associations dans la large acceptiondu terme. Ils émergent et se développent dans l'espace du travail où préexistent nombre d'associations, d'initiatives et d'intitulés divers. Syndicats et associations remplissent de surcroît, souvent, les mêmes fonctions et nourrissent, parfois, des objectifs similaires. L'ouvrage qui rassemble des contributions émanant d'historiens, de sociologues et de politistes s'essaie à analyser la diversité des relations qui se son...

  20. Algae associated with mangroves

    Dhargalkar, V.K.

    The algae associated with mangroves is described. Substrate plays very important role in algal establishment in intertidal and subtidal areas. Algae colonising the mud surface are seasonal because of the unstable conditions causEd. by the erosion...

  1. American Music Therapy Association

    American Music Therapy Association Home Contact News Help/FAQ Members Only Login Quick Links Facts About Music Therapy Qualifications ... with AMTA Sponsor AMTA Events Social Networking Support Music Therapy When you shop at AmazonSmile, Amazon will ...

  2. American Therapeutic Recreation Association

    ... Remember Me I forgot my password American Therapeutic Recreation Association Promoting Health & Wellness Services Annual Conference 2016 ... and leave your opinion Join thousands of Therapeutic Recreation specialists today Join Now Renew your membership today ...

  3. European Hematology Association

    Alexander, Walter


    Attendees at the 19th Congress of the European Hematology Association in Milan, Italy, heard reports on new therapies for acute myeloid leukemia, chronic lymphocytic leukemia, β-thalassemia, multiple myeloma, and polycythemia vera.

  4. American Sleep Association

    ... Public Health Professionals Join ASA Press Room American Sleep Association Share What is Sleep ? Insight into the ... Forums Contact Us Login Join ASA – for FREE Sleep Blog ASA Charitable Work – Sleeping Children Around the ...

  5. Interstitial Cystitis Association

    ... Video ICA’s Online Support Community A place for peace, hope, and advice. Join the Community ICA’s Healthcare ... urine test for diagnosing IC (similar to a pregnancy test), the Interstitial Cystitis Association (ICA) partnered with ...

  6. Generalized Multidimensional Association Rules

    周傲英; 周水庚; 金文; 田增平


    The problem of association rule mining has gained considerable prominence in the data mining community for its use as an important tool of knowl-edge discovery from large-scale databases. And there has been a spurt of research activities around this problem. Traditional association rule mining is limited to intra-transaction. Only recently the concept of N-dimensional inter-transaction as-sociation rule (NDITAR) was proposed by H.J. Lu. This paper modifies and extends Lu's definition of NDITAR based on the analysis of its limitations, and the general-ized multidimensional association rule (GMDAR) is subsequently introduced, which is more general, flexible and reasonable than NDITAR.

  7. Lewy Body Dementia Association

    ... promoting scientific advances. Featured LBD Stories & Tributes Dad's Dementia Journey It's been years since my father passed ... I received an email from the Lewy Body Dementia Association about a benefit... Read Story The Lewy ...

  8. Healthcare Associated Infections - State

    U.S. Department of Health & Human Services — The Healthcare-Associated Infections (HAI) measures - state data. These measures are developed by Centers for Disease Control and Prevention (CDC) and collected...

  9. Healthcare Associated Infections - National

    U.S. Department of Health & Human Services — The Healthcare-Associated Infections (HAI) measures - national data. These measures are developed by Centers for Disease Control and Prevention (CDC) and...

  10. National Rural Health Association

    ... Programs Overview State Rural Health Associations Rural Medical Education Rural Health Fellows Rural Health Fellows Program Application Volunteer Options NRHA Social Media Rural Health Students Education Liason Program National Rural Task Force NRHA Internships Government Affairs Save Rural ...

  11. Healthcare Associated Infections - Hospital

    U.S. Department of Health & Human Services — The Healthcare-Associated Infection (HAI) measures - provider data. These measures are developed by Centers for Disease Control and Prevention (CDC) and...

  12. Medical Library Association

    ... 11th, 2016 Patricia Flatley Brennan, registered nurse, informatician, industrial engineer, and renowned researcher is appointed as Director of the National Library of Medicine Tweets Copyright © 2016 Medical Library Association. ...

  13. Muscular Dystrophy Association

    ... 26.2 Miles For a Cure: Runner With Muscular Dystrophy Joins Team Momentum Ahead of Chicago Marathon Michelle ... FAQs Media Careers Contact Us Connect with MDA Muscular Dystrophy Association USA National Office 222 S. Riverside Plaza, Suite ...

  14. National Military Family Association

    ... 931.6632 © 2016 - National Military Family Association Twitter Facebook Pinterest Instagram Charity Navigator Four Star Charity GuideStar Exchange Better Business Bureau Charity Watch Independent Charity of America nonprofit ...

  15. American Tinnitus Association

    American Tinnitus Association Donate Become A Member Member Login Find A Provider Search form Search Menu Close Understanding The Facts Managing Your Tinnitus Research Toward A Cure About Us Initiatives News & ...

  16. American Lung Association

    ... Association's 'Tobacco 21' Initiative to Save Lives of Millennials, Future Generations by Raising Tobacco Sales Age to ... by lung disease. Help us continue to deliver education, advocacy and research to those who need it. $ ...

  17. Star clusters and associations

    All 33 papers presented at the symposium were inputted to INIS. They dealt with open clusters, globular clusters, stellar associations and moving groups, and local kinematics and galactic structures. (E.S.)

  18. Tourette Association Chapters

    ... TS in a classroom Symptoms occurring in classroom Executive Function Challenges Speech Therapies and Pathologies ADHD and OCD/ ... com/groups/311427567715/ Tourette Association Center of Excellence University of California, Los Angeles, Los Angeles, CA Director: ...

  19. Transverse Myelitis Association

    ... first large-scale North-American study of pediatric transverse myelitis LEARN MORE We are seeking over 100 patients ... TMA QUALITY OF LIFE FAMILY CAMP 2016 THE TRANSVERSE MYELITIS ASSOCIATION ADVOCATING FOR THOSE WITH ACUTE DISSEMINATED ENCEPHALOMYELITIS, ...

  20. Thyroid associated orbitopathy

    Rajat Maheshwari


    Full Text Available Thyroid associated orbitopathy, also known as Graves′ orbitopathy, is typically a self-limiting autoimmune process associated with dysthyroid states. The clinical presentation may vary from very mild disease to severe irreversible sight-threatening complications. Despite ongoing basic science and clinical research, the pathogenesis and highly effective therapeutic strategies remain elusive. The present article reviews the pathophysiology, clinical presentation, and management of this common, yet poorly understood disease, which remains a challenge to the ophthalmologist.

  1. Priapism Associated with Olanzapine

    S.H. Hosseini; A.K. Polonowita


    Priapism is a rare but serious adverse effect of psychotropic drugs where antipsychotic agents were implicated in 15 to 26% of priapism associated with medications. Among atypical antipsychotic, clozapine, risperidone and olanzapine have been reported to be associated with the condition. The patient was a 24 years old male referred to the OPD Clinic at Zare Psychiatry Hospital in 2007 with symptoms of delusion of control, delusion of persecution, delusion of somatic and auditory hallucination...

  2. Staff Association Information Meetings


    Staff Association Information Meetings: - Thursday 29 September at 2 p.m., Meyrin, Kjell Johnsen Auditorium, 30-7-017 (in French) - Friday 30 September at 10 a.m., Prévessin, BE Auditorium, 864-1-D02 (in French) - Monday 3 October at 2 p.m., Meyrin, IT Auditorium, 31-3-004 (in French) - Tuesday 4 October at 2 p.m., Meyrin, Filtration Plant, 222-R-001 (in English)   Staff Association

  3. Blastogenetic associations: General considerations.

    Lubinsky, Mark


    Associations of anomalies, with VACTERL as the prototype, have been the source of much debate, including questions about the validity and definition of this category. Evidence is presented for a teratologic basis for associations involving interactions between disruptive events and specific vulnerabilities. Because the embryo is organized in time and space, differences in the timing, location, and severity of exposures will create variable sequelae for any specific vulnerability, creating associations. The blastogenetic stage of development involves distinct properties that affect the nature of associations arising during this time, including relatively undifferentiated developmental fields and causally nonspecific malformations. With this, single anomalies can be part of the spectrum of findings that comprise a specific association. A specific defect defines a subset of disturbances, biasing frequencies of other defects. Processes are basic, integrated, and general, so disruptions are often lethal, and can have multiple effects, accounting for high incidences of multiple anomalies, and overlaps between associations. Blastogenetic disturbances also do not affect the late "fine tuning" of minor anomalies, although pathogenetic sequences can occur. This model suggests that certain combinations of congenital anomalies can arise from causally nonspecific teratogenetic fields determined by timing, location, and vulnerabilities, rather than polytopic developmental fields. PMID:26174333

  4. Immunological memory is associative

    Smith, D.J.; Forrest, S. [New Mexico Univ., Albuquerque, NM (United States). Dept. of Computer Science; Perelson, A.S. [Los Alamos National Lab., NM (United States)


    The purpose of this paper is to show that immunological memory is an associative and robust memory that belongs to the class of sparse distributed memories. This class of memories derives its associative and robust nature by sparsely sampling the input space and distributing the data among many independent agents. Other members of this class include a model of the cerebellar cortex and Sparse Distributed Memory (SDM). First we present a simplified account of the immune response and immunological memory. Next we present SDM, and then we show the correlations between immunological memory and SDM. Finally, we show how associative recall in the immune response can be both beneficial and detrimental to the fitness of an individual.

  5. Fibromyalgia syndrome. New associations.

    Waylonis, G W; Heck, W


    Previous research has demonstrated a number of conditions, such as sleep disturbance, fatigue, depression, spastic colon and mitral valve prolapse, associated with fibromyalgia. The present report describes additional symptoms and medical conditions that appear to be associated with the syndrome based on a survey of 554 individuals with fibromyalgia compared with a group of 169 controls. Individuals with fibromyalgia self report a greater incidence of bursitis, chondromalacia, constipation, diarrhea, temporomandibular joint dysfunction, vertigo, sinus and thyroid problems. Symptomatic complaints found statistically more prevalent in fibromyalgia patients included concentration problems, sensory symptoms, swollen glands and tinnitus. Other associations occurring with significant increased frequency were chronic cough, coccygeal and pelvic pain, tachycardia and weakness. Our previous report on inheritance patterns in fibromyalgia was reaffirmed with 12% reporting symptomatic children and 25% reporting symptomatic parents. Of the respondents, 70% noted that their symptoms were aggravated by noise, lights, stress, posture and weather. PMID:1466872

  6. Towards Predictive Association Theories

    Kontogeorgis, Georgios; Tsivintzelis, Ioannis; Michelsen, Michael Locht;


    Association equations of state like SAFT, CPA and NRHB have been previously applied to many complex mixtures. In this work we focus on two of these models, the CPA and the NRHB equations of state and the emphasis is on the analysis of their predictive capabilities for a wide range of applications...... phase equilibria in mixtures containing glycols. The importance of considering the solvation of CO2–water (in CPA) when the model is applied to multicomponent mixtures as well as of the multiple associations in heavy glycol–water mixtures (in NRHB) is investigated....

  7. Vaccine-Associated Uveitis.

    Benage, Matthew; Fraunfelder, Frederick W


    All of the widely administered vaccines have been reported to cause uveitis. The ocular inflammation is usually temporary and resolves with topical ocular steroids. During a 26-year period, a total of 289 cases of vaccine-associated uveitis were reported to three adverse reaction reporting databases. Hepatitis B vaccine, either alone or administered with other vaccines, appears to be the leading offender. Clinicians are encouraged to report cases of vaccine- or drug-associated ocular adverse reactions to PMID:27039491

  8. Acromegaly associated with gangliocytoma.

    Crowley, R K


    BACKGROUND: Acromegaly secondary to growth hormone-releasing hormone (GHRH) excess is rare. AIMS\\/CASE DESCRIPTION: We report two patients with acromegaly who were diagnosed with sellar gangliocytomas that were immunopositive for GHRH. Tumour tissue persisted after debulking surgery and in the second case this was associated with persistent growth hormone hypersecretion, successfully suppressed by a somatostatin analogue. CONCLUSIONS: The development of functional pituitary adenomas in association with sellar gangliocytomas is poorly understood. We present a brief discussion of the possible aetiology of these unusual pituitary tumours.

  9. The National Education Association.

    Sewall, Gilbert


    Examines how the National Education Association (NEA) has shifted from a conservative position to a more progressive one, which emphasizes militancy on such issues as equity and abolition of normative testing. Suggests that, in concentrating on politically charged matters, NEA has neglected a more important concern: the successful schooling of…

  10. AIDS and associated malignancies

    Charles; WOOD; William; HARRINGTON; Jr


    AIDS associated malignancies (ARL) is a major complication associated with AIDS patients upon immunosuppression.Chronically immunocompromised patients have a markedly increased risk of developing lymphoproliferative disease. In the era of potent antiretrovirals therapy (ARV), the malignant complications due to HIV- 1 infection have decreased in developed nations where ARV is administered, but still poses a major problem in developing countries where HIV- 1incidence is high and ARV is still not yet widely available. Even in ARV treated individuals there is a concern that the prolonged survival of many HIV- 1 carriers is likely to eventually result in an increased number of malignancies diagnosed.Malignancies that were found to have high incidence in HIV-infected individuals are Kaposi's sarcoma (KS), Hodgkin's disease (HD) and non-Hodgkin's lymphoma (NHL). The incidence of NHL has increased nearly 200 fold in HIV-positive patients, and accounts for a greater percentage of AIDS defining illness in the US and Europe since the advent of HAART therapy. These AIDS related lymphomas are distinct from their counterparts seen in HIV- 1 seronegative patients.For example nearly half of all cases of ARL are associated with the presence of a gamma herpesvirus, Epstein Barr virus (EBV) or human herpesvirus-8 (HHV-8)/Kaposi's sarcoma associated herpesvirus (KSHV). The pathogenesis of ARLs is complex. B-cell proliferation driven by chronic antigenemia resulting in the induction of polyclonal and ultimately monoclonal lymphoproliferation may occur in the setting of severe immunosuppression.

  11. JWST Associated Science Data Products

    Swade, D.; Alexov, A.; Bushouse, H.; Greene, G.; Swam, M.


    Associated science data products for the James Webb Space Telescope (JWST) will be generated within the Data Management Subsystem (DMS) of the Science and Operations Center at the Space Telescope Science Institute. Associations capture the relationship between exposures and higher level data products. Association Pools are generated to capture a list of exposures that could potentially form an association and provide relevant information about those exposures. The Association Generator runs within the calibration software to generate association definitions in an Association Table format. Based on the Association Table content, the calibration software creates the Associated Science Data Products.

  12. Amenorrhea associated with carotenemia.

    Kemmann, E; Pasquale, S A; Skaf, R


    Data are presented for ten women with anovulation, nine of them with amenorrhea, who have associated carotenemia. Classic explanations for carotenemia in amenorrheic patients have been weight loss or anorexia nervosa, yet carotenemia in our patients appeared to be diet induced. All patients consumed a pure or predominantly vegetarian diet; there was no intake of red meats. Clinical and laboratory data of the patients are presented. The amenorrhea of the patient is consistent with hypothalamic hypogonadotropic anovulation (HHA). It appeared that diet modification not only led to reduction in carotene levels, but also improved the menstrual status. The association of carotenemia and menstrual disorders is reviewed. The possibility that carotenemia is related to the development of HHA is discussed. PMID:6823046

  13. Fellows, Associates & Students Programmes


    The present document reviews the CERN Fellows, Associates and Students Programmes emphasizing the developments since 2000, when the previous review was presented to the Scientific Policy Committee, Finance Committee and Council (CERN/2325), and makes proposals for the coming five years. In summary, it is proposed to â?¢ Simplify the payment scheme for the Paid Scientific Associates Programme, which will no longer depend on candidateâ??s home support and age; â?¢ Broaden the scope of the Fellowship Programme, in order to facilitate the recruitment of young graduates in computing and engineering. Age-related eligibility conditions and payment levels will be replaced with experience-based criteria; â?¢ Modify subsistence rates for the Doctoral and Technical Student Programme in order to harmonize CERNâ??s payment levels with those offered by other research establishments. This document is presented for discussion and recommendation by the Scientific Policy Committee and approval by the Council. Additiona...

  14. Hom-power associative algebras

    Yau, Donald


    A generalization of power associative algebra, called Hom-power associative algebra, is studied. The main result says that a multiplicative Hom-algebra is Hom-power associative if and only if it satisfies two identities of degrees three and four. It generalizes Albert's result that power associativity is equivalent to third and fourth power associativity. In particular, multiplicative right Hom-alternative algebras and non-commutative Hom-Jordan algebras are Hom-power associative.

  15. Carcinoma-associated antigens

    This invention relates to novel antigens associated with breast carcinoma, anti-sera specific to said antigens, 125I-labeled forms of said antigens and methods of detecting said antigens in serum or plasma. The invention also relates to a diagnostic kit containing standardised antigens or antisera or marked forms thereof for the detection of said antigens in human blood, serum or plasma. (author)

  16. Myeloma associated systemic amyloidosis

    Lakshmi Kumari N


    Full Text Available This is a case report of myeloma associated systemic amyloidosis in a 45 years old man. The patient presented with asymptomatic plaques and papules around the eyes, nostrils, anus, inguinal region and tongue. Purpuric lesions were noticed on and off over the lesions. When thorough investigations were undertaken they revealed multiple myeloma. Histopathology with amyloid stain positivity and bone marrow examination confirmed the diagnosis.

  17. Infliximab-associated Chiasmopathy

    Farrell, Erin; Sacks, Joel G.


    Optic neuropathy has been reported in association with the use of tumor necrosis factor-alpha antagonists such as etanercept, infliximab, and adalimumab. This is a report of a patient who began experiencing decreased vision approximately 1 month after starting infliximab therapy for rheumatoid arthritis. Visual field testing showed bitemporal hemianopic scotomas, indicating involvement of the nerve fibers in the optic chiasm. The infliximab was discontinued, and the patient experienced substa...

  18. Time and Associative Learning

    Balsam, Peter D; Drew, Michael R.; Gallistel, C.R.


    In a basic associative learning paradigm, learning is said to have occurred when the conditioned stimulus evokes an anticipatory response. This learning is widely believed to depend on the contiguous presentation of conditioned and unconditioned stimulus. However, what it means to be contiguous has not been rigorously defined. Here we examine the empirical bases for these beliefs and suggest an alternative view based on the hypothesis that learning about the temporal relationships between eve...

  19. Angioedema Associated with Haloperidol

    AlMadhyan, Abdulmajeed Brahim


    Haloperidol is one of the antipsychotic medications which are widely used in the emergency department and its association with angioedema which is very rarely reported in scientific literature. One of the serious situations in the emergency department is angioedema and it bends airway obstruction which is need early attention and treatment. A case was reported which was observed at a governmental hospital in Riyadh. An adult female developed angioedema after single dose of Haloperidol intramu...

  20. Quantum Associative Memory

    Ventura, Dan; Martinez, Tony


    This paper combines quantum computation with classical neural network theory to produce a quantum computational learning algorithm. Quantum computation uses microscopic quantum level effects to perform computational tasks and has produced results that in some cases are exponentially faster than their classical counterparts. The unique characteristics of quantum theory may also be used to create a quantum associative memory with a capacity exponential in the number of neurons. This paper combi...

  1. Reminders Through Association.

    Rogers, Todd; Milkman, Katherine L


    People often fail to follow through on good intentions. While limited self-control is frequently the culprit, another cause is simply forgetting to enact intentions when opportunities arise. We introduce a novel, potent approach to facilitating follow-through: the reminders-through-association approach. This approach involves associating intentions (e.g., to mail a letter on your desk tomorrow) with distinctive cues that will capture attention when you have opportunities to act on those intentions (e.g., Valentine's Day flowers that arrived late yesterday, which are sitting on your desk). We showed that cue-based reminders are more potent when the cues they employ are distinctive relative to (a) other regularly encountered stimuli and (b) other stimuli encountered concurrently. Further, they can be more effective than written or electronic reminder messages, and they are undervalued and underused. The reminders-through-association approach, developed by integrating and expanding on past research on self-control, reminders, and prospective memory, can be a powerful tool for policymakers and individuals. PMID:27207873

  2. Scoliosis Associated With Syringomyelia

    Gh Fathi


    Full Text Available Introduction: The differential diagnosis of idiopathic and syringomyelia associated scoliosis is important because corrective surgery for scoliosis associated with syringomyelia prior to management of syringomyelia can be dangerous. There are important imaging indicators for diagnosis of syringomyelia associated with scoliosis. A few of these indicators have been assessed in our study. Methods: A retrospective descriptive study including 38 patients with both scoliosis and syringomyelia was performed at the Shafa Yahyaeian center. Standard scoliosis series radiographs and MRI of all patients were studied. The type of scoliosis, location and magnitude of deformity, kyphosis or lordosis in the sagittal plane, location and size of syrinx were assessed. Results: Thoracic kyphosis was present in 94.7% of patients. 37% of patients had scoliosis with convexity to left. Arnold –chiari malformation was present in 36% and cord tethering in 21% of patients. The locations of syrinx were as follows: 47.4%cervical, 44.6 thoracic, 2.7% lumbar and 5.3% were holocord. Conclusion: Kyphosis, abscence of lordosis in sagittal plane, progressive scoliosis and scoliosis with convexity to left are atypical findings and could be indicators of the presence of syringomyelia. If these indicators are present, a diagnosis of idiopathic scoliosis should be made with caution.

  3. Osteosarcoma associated with hyperparathyroidism

    Jutte, Paul C. [Istituti Orthopedici Rizzoli, Via Pupilli 1, 40136, Bologna (Italy); University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen (Netherlands); Rosso, Renato [Anatomia Patologica Universita di Pavia, via Forlanini 16, 27100, Pavia (Italy); Paolis, Massimiliano de; Errani, Costatino; Pasini, Elisabetta; Campanacci, Laura; Bacci, Gaetano; Bertoni, Franco; Mercuri, Mario [Istituti Orthopedici Rizzoli, Via Pupilli 1, 40136, Bologna (Italy)


    The fourth case in the literature is presented of a patient with the rare association of hyperparathyroidism and osteosarcoma. A 56-year-old woman presented with hyperparathyroidism and a lesion in the tibia. Initial diagnosis was brown tumor. Histology, however, revealed osteosarcoma, and the patient was treated accordingly. The experimental induction of osteosarcoma by parathormone in rodent studies makes this finding alarming, considering the increasing use of parathormone in the treatment of osteoporosis. The mechanism by which osteosarcoma is induced in humans cannot be explained based on current knowledge of mechanisms of action of parathyroid hormone. (orig.)

  4. Osteosarcoma associated with hyperparathyroidism

    The fourth case in the literature is presented of a patient with the rare association of hyperparathyroidism and osteosarcoma. A 56-year-old woman presented with hyperparathyroidism and a lesion in the tibia. Initial diagnosis was brown tumor. Histology, however, revealed osteosarcoma, and the patient was treated accordingly. The experimental induction of osteosarcoma by parathormone in rodent studies makes this finding alarming, considering the increasing use of parathormone in the treatment of osteoporosis. The mechanism by which osteosarcoma is induced in humans cannot be explained based on current knowledge of mechanisms of action of parathyroid hormone. (orig.)

  5. Perindopril-associated pneumonitis.

    Benard, A; Melloni, B; Gosselin, B; Bonnaud, F; Wallaert, B


    We report two cases of perindopril-associated pneumonitis with typical drug-induced clinical features. In the first case, biopsies showed granulomatous sarcoid-like lesions; in the second, bronchial wall eosinophil infiltratf2p4was reported with increased blood eosinophil count. In these two cases, improvement was obtained by withdrawal of the drug and was completed with steroids. All other causes were ruled out. Angiotensin-converting enzyme inhibitor (ACEI)-induced pneumonitis is still rare but has to be recognized as a real side-effect. PMID:8804953

  6. Selective association rule generation

    Hahsler, Michael; Hornik, Kurt


    Mining association rules is a popular and well researched method for discovering interesting relations between variables in large databases. A practical problem is that at medium to low support values often a large number of frequent itemsets and an even larger number of association rules are found in a database. A widely used approach is to gradually increase minimum support and minimum confidence or to filter the found rules using increasingly strict constraints on additional measures of interestingness until the set of rules found is reduced to a manageable size. In this paper we describe a different approach which is based on the idea to first define a set of ``interesting'' itemsets (e.g., by a mixture of mining and expert knowledge) and then, in a second step to selectively generate rules for only these itemsets. The main advantage of this approach over increasing thresholds or filtering rules is that the number of rules found is significantly reduced while at the same time it is not necessary to increa...

  7. Hemimyeloschisis associated with hydrocephalus.

    Izci, Yusuf


    Hemimyeloschisis is a very rare congenital malformation of the spine which is characterized by a split cord malformation associated with complete exposureof the one hemicord to the exterior. We report a case of hemimyeloschisis on the right hemicord in a patient with hydrocephalus. The patient was a female neonate with myeloschisis, skin defect, and hypertrichosis visible at birth in the upper lumbar region. There was also skin defect around the myeloschisis. Computed tomography (CT) revealed a bony septum at the L2 level as well as the myeloschisis on the right hemicord, which enabled us to make a precise preoperative diagnosis of this rare malformation. There was also mild hydrocephalus in cranial CT scan. Closure of the myeloschisis and removal of the septum were successfully performed associated with the closure of the skin in one stage surgery to prevent subsequent infection and neurological deterioration. Ventriculoperitoneal shunt insertion was performed for hydrocephalus. The presence of combined split cord malformation and myeloschisis is consistent with the hypothesis of an ontogenic basis of development. This combination also emphasizes the importance of early imaging for diagnosis in this complex malformation. PMID:26607795

  8. The All Sky Young Association (ASYA): a new young association

    Torres, C A O; Montes, D


    To analyze the SACY (Search for Associations Containing Young stars) survey we developed a method to find young associations and to define their high probability members. These bona fide members enable to obtain the kinematical and the physical properties of each association in a proper way. Recently we noted a concentration in the UV plane and we found a new association we are calling ASYA (All Sky Young Association) for its overall distribution in the sky with a total of 38 bonafide members and an estimated age of 110 Myr, the oldest young association found in the SACY survey. We present here its kinematical, space and Li distributions and its HR diagram.

  9. Urolithiasis associated with topiramate

    Scott Eggener


    Full Text Available OBJECTIVE: Topiramate is a sulfamate-substituted monosaccharide anticonvulsant used as adjunctive therapy for intractable refractory seizures. It is report a case of topiramate-induced urolithiasis. CASE REPORT: A 35-year-old man presented with acute, right-sided, colicky flank pain. He denied hematuria or dysuria. He was in use of phenytoin, risperidone, phenobarbital, and topiramate. The total daily dose of topiramate was 375 mg. A CT scan showed a 7 x 1 mm curvilinear density at the right ureterovesical junction with proximal hydrouretronephrosis. He was managed with rigid ureteroscopic stone extraction and the calculus metabolic analysis revealed the stone was composed of carbonate apatite (70%, calcium oxalate dihydrate (20%, and calcium oxalate monohydrate (10%. COMMENTS: The present case typifies many features of topiramate-induced urolithiasis. Those who care for patients with urinary stone disease should be aware of this association.

  10. MUTYH Associated Polyposis (MAP)

    Poulsen, Marie Louise Mølgaard; Bisgaard, M L


    MUTYH Associated Polyposis (MAP), a Polyposis predisposition caused by biallelic mutations in the Base Excision Repair (BER) gene MUTYH, confers a marked risk of colorectal cancer (CRC). The MAP phenotype is difficult to distinguish from other hereditary CRC syndromes. Especially from Familial...... Adenomatous Polyposis (FAP) and to a lesser extend Lynch Syndrome, which are caused by germline mutations in the APC and Mismatch Repair (MMR) genes, respectively.Here we review research findings regarding MUTYH interactions, genotypic and phenotypic characteristics of MAP, as well as surveillance and...... treatment of the disease. The applied papers, published between 1/1 2002- 1/2 2008, were found through PubMed.The exact role of MUTYH in CRC tumorgenesis is still uncertain, although MAP tumors show distinct molecular features, including somatic G:C>T:A transversions in the APC gene. Furthermore...

  11. Pancytopenia associated with clonazepam

    Hsueh Chung-Tsen


    Full Text Available Abstract We report a case of a 48-year-old Chinese female with end-stage renal disease and chronic anemia on hemodialysis. Clonazepam was prescribed for myoclonus disorder two weeks prior to her hospitalization. Subsequently, she was hospitalized for neutropenic fever with thrombocytopenia and worsening anemia. Bone marrow examination demonstrated a markedly hypocellular marrow (10-20% total cellularity. Clonazepam was discontinued, with gradual improvement of thrombocytopenia, and neutropenia in 1-2 weeks. To our knowledge, this is the first reported case of pancytopenia associated with clonazepam. We recommend patients taking clonazepam to be monitored with regular complete blood count to check for clinically significant pancytopenia or thrombocytopenia.

  12. TILLING and Associated Technologies

    Trevor Wang; Cristobal Uauy; Brad Till; Chun-Ming Liu


    @@ As part of a collaboration between the John Innes Centre(JIC),Norwich,UK and the Centre for Signal Transduction and Metabolomics(C-STM)at the Institute of Botany(IOB),the Chinese Academy of Sciences,Beijing,a workshop on 'TILLING and Associated Technologies' was held at the IOB on 15-16 April 2010.Through sponsorship from the UK Biotechnology and Biological Sciences Research Council(BBSRC),Resarch Councils UK,China Office,and the Transgenic Research Project of China,experts were drawn from the USA,Europe and China to present their latest information on technology development for targeted single nucleotide polymorphism(SNP)detection to over 60 registered participants.

  13. HIV-Associated Tuberculosis.

    Naidoo, Kogieleum; Naidoo, Kasavan; Padayatchi, Nesri; Abdool Karim, Quarraisha


    The intersecting HIV and Tuberculosis epidemics in countries with a high disease burden of both infections pose many challenges and opportunities. For patients infected with HIV in high TB burden countries, the diagnosis of TB, ARV drug choices in treating HIV-TB coinfected patients, when to initiate ARV treatment in relation to TB treatment, managing immune reconstitution, minimising risk of getting infected with TB and/or managing recurrent TB, minimizing airborne transmission, and infection control are key issues. In addition, given the disproportionate burden of HIV in women in these settings, sexual reproductive health issues and particular high mortality rates associated with TB during pregnancy are important. The scaleup and resource allocation to access antiretroviral treatment in these high HIV and TB settings provide a unique opportunity to strengthen both services and impact positively in meeting Millennium Development Goal 6. PMID:20871843

  14. On the associative Nijenhuis Relation

    Ebrahimi-Fard, Kurusch


    In this brief note we would like to give the construction of a free commutative unital associative Nijenhuis algebra on a commutative unital associative algebra based on an augmented modified quasi-shuffle product.

  15. Submanifolds Weakly Associated with Graphs

    A Carriazo; L M Fernández; A Rodríguez-Hidalgo


    We establish an interesting link between differential geometry and graph theory by defining submanifolds weakly associated with graphs. We prove that, in a local sense, every submanifold satisfies such an association, and other general results. Finally, we study submanifolds associated with graphs either in low dimensions or belonging to some special families.

  16. The Growth-Inequality Association:

    Bjørnskov, Christian


    This note suggests that the association between income inequality and economic growth rates might arguably depend on the political ideology of incumbent governments. Estimates indicate that under leftwing governments, inequality is negatively associated with growth while the association is positive...... under rightwing governments. This may provide a qualification to recent studies of inequality....

  17. Associative Hierarchical Random Fields.

    Ladický, L'ubor; Russell, Chris; Kohli, Pushmeet; Torr, Philip H S


    This paper makes two contributions: the first is the proposal of a new model-The associative hierarchical random field (AHRF), and a novel algorithm for its optimization; the second is the application of this model to the problem of semantic segmentation. Most methods for semantic segmentation are formulated as a labeling problem for variables that might correspond to either pixels or segments such as super-pixels. It is well known that the generation of super pixel segmentations is not unique. This has motivated many researchers to use multiple super pixel segmentations for problems such as semantic segmentation or single view reconstruction. These super-pixels have not yet been combined in a principled manner, this is a difficult problem, as they may overlap, or be nested in such a way that the segmentations form a segmentation tree. Our new hierarchical random field model allows information from all of the multiple segmentations to contribute to a global energy. MAP inference in this model can be performed efficiently using powerful graph cut based move making algorithms. Our framework generalizes much of the previous work based on pixels or segments, and the resulting labelings can be viewed both as a detailed segmentation at the pixel level, or at the other extreme, as a segment selector that pieces together a solution like a jigsaw, selecting the best segments from different segmentations as pieces. We evaluate its performance on some of the most challenging data sets for object class segmentation, and show that this ability to perform inference using multiple overlapping segmentations leads to state-of-the-art results. PMID:26353271

  18. Associated particle imaging (API)



    Associated Particle Imaging (API) is an active neutron probe technique that provides a 3-D image with elemental composition of the material under interrogation, and so occupies a unique niche in the interrogation of unknown objects. The highly penetrating nature of neutrons enables API to provide detailed information about targets of interest that are hidden from view. Due to the isotropic nature of the induced reactions, radiation detectors can be set on the same side of the object as the neutron source, so that the object can be interrogated from a single side. At the heat of the system is a small generator that produces a continuous, monoenergetic flux of neutrons. By measuring the trajectory of coincident alpha particles that are produced as part of the process, the trajectory of the neutron can be inferred. Interactions between a neutron and the material in its path often produce a gamma ray whose energy is characteristic of that material. When the gamma ray is detected, its energy is measured and combined with the trajectory information to produce a 3-D image of the composition of the object being interrogated. During the course of API development, a number of improvements have been made. A new, more rugged sealed Tube Neutron Generator (STNG) has been designed and fabricated that is less susceptible to radiation damage and better able to withstand the rigors of fielding than earlier designs. A specialized high-voltage power supply for the STNG has also been designed and built. A complete package of software has been written for the tasks of system calibration, diagnostics and data acquisition and analysis. A portable system has been built and field tested, proving that API can be taken out of the lab and into real-world situations, and that its performance in the field is equal to that in the lab.

  19. Lexical Creativity from Word Associations

    Gross, Oskar; Toivonen, Hannu; Toivanen, Jukka; Valitutti, Alessandro


    A fluent ability to associate tasks, concepts, ideas, knowledge and experiences in a relevant way is often considered an important factor of creativity, especially in problem solving. We are interested in providing computational support for discovering such creative associations. In this paper we design minimally supervised methods that can perform well in the remote associates test (RAT), a well-known psychometric measure of creativity. We show that with a large corpus of text and some relat...

  20. Interfacial Protein-Protein Associations

    Langdon, Blake B.; Kastantin, Mark; Walder, Robert; Schwartz, Daniel K.


    While traditional models of protein adsorption focus primarily on direct protein-surface interactions, recent findings suggest that protein-protein interactions may play a central role. Using high-throughput intermolecular resonance energy transfer (RET) tracking, we directly observed dynamic, protein-protein associations of bovine serum albumin on poly(ethylene glycol) modified surfaces. The associations were heterogeneous and reversible, and associating molecules resided on the surface for ...

  1. Dengue-associated neuromuscular complications

    Ravindra Kumar Garg; Hardeep Singh Malhotra; Amita Jain; Kiran Preet Malhotra


    Dengue is associated with many neurological dysfunctions. Up to 4% of dengue patients may develop neuromuscular complications. Muscle involvement can manifest with myalgias, myositis, rhabdomyolysis and hypokalemic paralysis. Diffuse myalgia is the most characteristic neurological symptom of dengue fever. Dengue-associated myositis can be of varying severity ranging from self-limiting muscle involvement to severe dengue myositis. Dengue-associated hypokalemic paralysis often has a rapidly evo...

  2. Associative learning and animal cognition

    Dickinson, Anthony


    Associative learning plays a variety of roles in the study of animal cognition from a core theoretical component to a null hypothesis against which the contribution of cognitive processes is assessed. Two developments in contemporary associative learning have enhanced its relevance to animal cognition. The first concerns the role of associatively activated representations, whereas the second is the development of hybrid theories in which learning is determined by prediction errors, both direc...

  3. Hiding Sensitive Association Rule Using Clusters of Sensitive Association Rule

    Sanjay keer


    Full Text Available The security of the large database that contains certain crucialinformation, it will become a serious issue when sharing data to thenetwork against unauthorized access. Association rules hidingalgorithms get strong and efficient performance for protectingconfidential and crucial data. The objective of the proposedAssociation rule hiding algorithm for privacy preserving datamining is to hide certain information so that they cannot bediscovered through association rule mining algorithm. The mainapproached of association rule hiding algorithms to hide somegenerated association rules, by increase or decrease the support orthe confidence of the rules. The association rule items whether inLeft Hand Side (LHS or Right Hand Side (RHS of the generatedrule, that cannot be deduced through association rule miningalgorithms. The concept of Increase Support of Left Hand Side(ISL algorithm is decrease the confidence of rule by increase thesupport value of LHS. It doesn’t work for both side of rule. Itworks only for modification of LHS. In this paper, we propose aheuristic algorithm named ISLRC (Increase Support of L.H.S. itemof Rule Clusters based on ISL approach to preserve privacy forsensitive association rules in database. Proposed algorithmmodifies fewer transactions and hides many rules at a time. Theefficiency of the proposed algorithm is compared with ISLalgorithms.

  4. Rhabdomyolysis Associated with Parainfluenza Virus

    Miltiadis Douvoyiannis


    Full Text Available Influenza virus is the most frequently reported viral cause of rhabdomyolysis. A 7-year-old child is presented with rhabdomyolysis associated with parainfluenza type 2 virus. Nine cases of rhabdomyolysis associated with parainfluenza virus have been reported. Complications may include electrolyte disturbances, acute renal failure, and compartment syndrome.

  5. African Diaspora Associations in Denmark

    Vammen, Ida Marie; Trans, Lars Ove


    Since the early 1990s, an increasing number of African migrants have come to Denmark, where they have formed a large number of migrant associations. This chapter presents selected findings from a comprehensive survey of African diaspora associations in Denmark and focuses specifically on their...

  6. Domain Bridging Associations Support Creativity

    Kötter, Tobias; Thiel, Kilian; Berthold, Michael R


    This paper proposes a new approach to support creativity through assisting the discovery of unexpected associations across different domains. This is achieved by integrating information from heterogeneous domains into a single network, enabling the interactive discovery of links across the corresponding information resources. We discuss three different pattern of domain crossing associations in this context.




  8. Weak associativity and deformation quantization

    V.G. Kupriyanov


    Full Text Available Non-commutativity and non-associativity are quite natural in string theory. For open strings it appears due to the presence of non-vanishing background two-form in the world volume of Dirichlet brane, while in closed string theory the flux compactifications with non-vanishing three-form also lead to non-geometric backgrounds. In this paper, working in the framework of deformation quantization, we study the violation of associativity imposing the condition that the associator of three elements should vanish whenever each two of them are equal. The corresponding star products are called alternative and satisfy important for physical applications properties like the Moufang identities, alternative identities, Artin's theorem, etc. The condition of alternativity is invariant under the gauge transformations, just like it happens in the associative case. The price to pay is the restriction on the non-associative algebra which can be represented by the alternative star product, it should satisfy the Malcev identity. The example of nontrivial Malcev algebra is the algebra of imaginary octonions. For this case we construct an explicit expression of the non-associative and alternative star product. We also discuss the quantization of Malcev–Poisson algebras of general form, study its properties and provide the lower order expression for the alternative star product. To conclude we define the integration on the algebra of the alternative star products and show that the integrated associator vanishes.

  9. Weak associativity and deformation quantization

    Kupriyanov, V. G.


    Non-commutativity and non-associativity are quite natural in string theory. For open strings it appears due to the presence of non-vanishing background two-form in the world volume of Dirichlet brane, while in closed string theory the flux compactifications with non-vanishing three-form also lead to non-geometric backgrounds. In this paper, working in the framework of deformation quantization, we study the violation of associativity imposing the condition that the associator of three elements should vanish whenever each two of them are equal. The corresponding star products are called alternative and satisfy important for physical applications properties like the Moufang identities, alternative identities, Artin's theorem, etc. The condition of alternativity is invariant under the gauge transformations, just like it happens in the associative case. The price to pay is the restriction on the non-associative algebra which can be represented by the alternative star product, it should satisfy the Malcev identity. The example of nontrivial Malcev algebra is the algebra of imaginary octonions. For this case we construct an explicit expression of the non-associative and alternative star product. We also discuss the quantization of Malcev-Poisson algebras of general form, study its properties and provide the lower order expression for the alternative star product. To conclude we define the integration on the algebra of the alternative star products and show that the integrated associator vanishes.



  11. Discovering fuzzy spatial association rules

    Kacar, Esen; Cicekli, Nihan K.


    Discovering interesting, implicit knowledge and general relationships in geographic information databases is very important to understand and use these spatial data. One of the methods for discovering this implicit knowledge is mining spatial association rules. A spatial association rule is a rule indicating certain association relationships among a set of spatial and possibly non-spatial predicates. In the mining process, data is organized in a hierarchical manner. However, in real-world applications it may not be possible to construct a crisp structure for this data, instead some fuzzy structures should be used. Fuzziness, i.e. partial belonging of an item to more than one sub-item in the hierarchy, could be applied to the data itself, and also to the hierarchy of spatial relations. This paper shows that, strong association rules can be mined from large spatial databases using fuzzy concept and spatial relation hierarchies.

  12. Association models for petroleum applications

    Kontogeorgis, Georgios


    thermodynamic models like cubic equations of state have been the dominating tools in the petroleum industry, the focus of this review is on the association models. Association models are defined as the models of SAFT/CPA family (and others) which incorporate hydrogen bonding and other complex interactions. Such...... association models have been, especially over the last 20 years, proved to be very successful in predicting many thermodynamic properties in the oil & gas industry. They have not so far replaced cubic equations of state, but the results obtained by using these models are very impressive in many cases, e.......g., for gas hydrate related systems, CO2/H2S mixtures, water/hydrocarbons and others. This review highlights both the major advantages of these association models and some of their limitations, which we believe should be discussed in the future....

  13. Information Retrieval Using Association Lists

    Marek Gajecki


    The paper presents the main models of information retrieval in text. The idea of association list and its use for information retrieval is introduced. The paper contains the evaluation results of the algorithms under discussion.

  14. Information Retrieval Using Association Lists

    Marek Gajecki


    Full Text Available The paper presents the main models of information retrieval in text. The idea of association list and its use for information retrieval is introduced. The paper contains the evaluation results of the algorithms under discussion.

  15. Anencephaly and its Associated Malformations

    Gole, Ravikiran Ashok; Meshram, Pritee Madan; Hattangdi, Shanta Sunil


    Introduction: Anencephaly is a serious neural tube defect in which parts of the brain and skull are not developed. But apart from this it is also associated with other malformations which are not related to neural tube in development.

  16. American Association Of State Climatologists

    National Oceanic and Atmospheric Administration, Department of Commerce — Records documenting the business, membership, and meetings of the American Association of State Climatologists, from 1976-92. Material donated in 2008 by the estate...

  17. Business Associations and Private Ordering

    Prüfer, J.


    Abstract: We study the capacity of business associations - private, formal, noncommercial organizations designed to promote the common business interests of their members - to support contract enforcement and collective action. Inspired by recent empirical literature, our theoretical framework conne

  18. Thrombocytopenia Associated with Levodopa Treatment

    Ku-Eun Lee


    Full Text Available There were few cases of thrombocytopenia associated with levodopa. Herein, we report a patient with Parkinson’s disease, who suffered thrombocytopenia related to long-term use of levodopa.

  19. HPV-Associated Cancers Statistics

    ... What CDC Is Doing Related Links Stay Informed Statistics for Other Kinds of Cancer Breast Cervical Colorectal ( ... Vaginal and Vulvar Cancer Home HPV-Associated Cancer Statistics Language: English Español (Spanish) Recommend on Facebook Tweet ...

  20. Health Conditions Associated with Psoriasis

    ... Zipcode Comorbidities Associated with Psoriatic Disease People with psoriasis and psoriatic arthritis are at an elevated risk ... conditions. Psoriasis and Psoriatic Arthritis Psoriasis Psoriatic Arthritis Psoriasis and Psoriatic Arthritis Cancer A number of studies ...

  1. Associated with Health Care-Associated Infections in Cardiac Surgery

    Greco, Giampaolo; Shi, Wei; Michler, Robert E.; Meltzer, David O.; Ailawadi, Gorav; Hohmann, Samuel F.; Thourani, Vinod; Argenziano, Michael; Alexander, John; Sankovic, Kathy; Gupta, Lopa; Blackstone, Eugene H.; Acker, Michael A.; Russo, Mark J.; Lee, Albert; Burks, Sandra G.; Gelijns, Annetine C.; Bagiella, Emilia; Moskowitz, Alan J.; Gardner, Timothy J.


    BACKGROUND Health care-associated infections (HAIs) are the most common noncardiac complications after cardiac surgery and are associated with increased morbidity and mortality. Current information about their economic burden is limited. OBJECTIVES To determine the cost associated with major types of HAIs during the first 2 months after cardiac surgery. METHODS Prospectively collected data from a multicenter observational study of the Cardiothoracic Surgery Clinical Trials Network, in which patients were monitored for infections for 65 days after surgery, were merged with related financial data, routinely collected by the University HealthSystem Consortium. Incremental length of stay (LOS) and cost associated with HAIs were estimated using generalized linear models, adjusting for patient demographics, clinical history, baseline laboratory values, and surgery type. RESULTS Among 4,320 cardiac surgery patients, mean age of 64 ± 13 years, 119 (2.8%) experienced a major HAI during the index hospitalization. The most common HAIs were pneumonia (48%), sepsis (20%) and C. Difficile colitis (18%). On average, the estimated incremental cost associated with a major HAI was nearly $38,000, of which 47% was related to intensive care unit services. The incremental LOS was 14 days. Overall, there were 849 readmissions, among these, 8.7% were attributed to major HAIs. The cost of readmissions due to major HAI was on average nearly three times as much as readmissions not related to HAI. CONCLUSIONS Hospital cost, length of stay, and readmissions are strongly associated with HAIs. These associations suggest the potential for large reductions in costs if HAIs following cardiac surgery can be reduced. PMID:25572505

  2. Clostridium difficile-associated diarrhoea.

    Wight, N.; Curtis, H.; Hyde, J.; Borriello, S P; Mahida, Y R


    At our hospital, the number of cases of Clostridium difficile-associated diarrhoea increased from 29 in 1993 to 210 in 1995. The case notes of 110 patients with C difficile-associated diarrhoea during the first 6 months of 1995 were analysed retrospectively. The majority of the patients (106) had received antibiotics before the onset of diarrhoea; 46 had received three or more different antibiotics and 28 had received metronidazole. In 19 patients, the first stool sample after the onset of di...

  3. Associative memories in nuclear physics

    Experiments in nuclear physics involve the use of large size 'memories'. After showing the difficulties arising from the use of such memories, the authors give the principles of the various programming methods which make it possible to operate the memories associatively thus benefiting from a reduction in size and better operational conditions. They attempt to estimate the shape and dimensions of an associative memory with cable connections which could be designed specially for nuclear research, contrary to those actually in service. (authors)

  4. Insomnia: prevalence and associated factors

    Lopes, Cátia; Lopes, Daniela; Ferreira, Sofia; Correia, Teresa; Pinto, Isabel C.


    Nowadays sleep disorders are very common and affect most of the population, the most common may be insomnia. Insomnia is defined as the difficulty of initiating or maintaining sleep it, may also be reflected in an early wake up and by the presence of a non-restful sleep and it is associated with impairment in social and occupational functioning of the individual. Knowing the prevalence and the associated factors of insomnia. This is a cross-sectional epidemiological study. The pop...

  5. Vitiligo associated with esophageal adenocarcinoma

    Ali Asilian


    Full Text Available Vitiligo is a disease that results in depigmented areas in the skin. It may develop at any age but the average age at onset is 20 years. Association of vitiligo and melanoma has been commonly reported, but malignancies other than melanoma have been rarely associated with vitiligo. We report a 73-year-old patient with new onset vitiligo who developed esophageal adenocarcinoma in the following years.

  6. Phenomena Associated With EIT Waves

    Thompson, B. J.; Biesecker, D. A.; Gopalswamy, N.


    We discuss phenomena associated with "EIT Wave" transients. These phenomena include coronal mass ejections, flares, EUV/SXR dimmings, chromospheric waves, Moreton waves, solar energetic particle events, energetic electron events, and radio signatures. Although the occurrence of many phenomena correlate with the appearance of EIT waves, it is difficult to mfer which associations are causal. The presentation will include a discussion of correlation surveys of these phenomena.

  7. Pyoderma Gangrenosum - Variants And Associations

    Sentamilselvi G


    Full Text Available Six cases of pyoderma gangrenosum encountered with in a period of 2 years are described here with their clinical presentations and associations. Three patients were cases of superficial granulomatous pyoderma and three were of ulcerative type. Rheumatoid arthritis was found to be the associated disease in one of the cases of ulcerative type. Response to therapy was satisfactory in all of them expect in one case of ulcerative pyoderma gangrenosum who was resistant to most of the available therapeutic modalities.

  8. Associative Concept Learning in Animals

    Zentall, Thomas R; Wasserman, Edward A.; Urcuioli, Peter J


    Nonhuman animals show evidence for three types of concept learning: perceptual or similarity-based in which objects/stimuli are categorized based on physical similarity; relational in which one object/stimulus is categorized relative to another (e.g., same/different); and associative in which arbitrary stimuli become interchangeable with one another by virtue of a common association with another stimulus, outcome, or response. In this article, we focus on various methods for establishing asso...

  9. HIV-associated anal cancer

    Newsom-Davis, Thomas; Bower, Mark


    HIV-associated anal carcinoma, a non-AIDS-defining cancer, is a human papillomavirus-associated malignancy with a spectrum of preinvasive changes. The standardized incidence ratio for anal cancer in patients with HIV/AIDS is 20-50. Algorithms for anal cancer screening include anal cytology followed by high-resolution anoscopy for those with abnormal findings. Outpatient topical treatments for anal intraepithelial neoplasia include infrared coagulation therapy, trichloroacetic acid, and imiqui...

  10. Disability associated with mental disorders

    Chaudhury, Pranit K.; Deka, Kamala; Chetia, Dhrubajyoti


    Background: Disability associated with mental illness is a major contributor to the global burden of disease. The present study looks at some aspects of disability associated with 7 psychiatric disorders: schizophrenia, bipolar affective disorder, anxiety disorders, depression, obsessive–compulsive disorder, dementia, and mental and behavioural disorders due to the use of alcohol. Aims: (i) To evaluate the nature and quantity of disabilities in the study groups; (ii) to compare the degree of ...

  11. Measuring Linear and Nonlinear Associations

    Masoud Yarmohammadi


    In this study, we propose a new approach based on two nonparametric techniques to capture the linear and nonlinear associations. The singular spectrum analysis technique, which is a powerful method for filtering noisy series, is used as a noise reduction method and mutual information is considered for measuring the level of association. The performance of the proposed approach is assessed using the simulated and real time series.

  12. Dengue-associated neuromuscular complications

    Ravindra Kumar Garg


    Full Text Available Dengue is associated with many neurological dysfunctions. Up to 4% of dengue patients may develop neuromuscular complications. Muscle involvement can manifest with myalgias, myositis, rhabdomyolysis and hypokalemic paralysis. Diffuse myalgia is the most characteristic neurological symptom of dengue fever. Dengue-associated myositis can be of varying severity ranging from self-limiting muscle involvement to severe dengue myositis. Dengue-associated hypokalemic paralysis often has a rapidly evolving course; benign nature; excellent response to potassium; and, often leads to diagnostic confusion with other dengue-associated neuromuscular disorders. Rhabdomyolysis is the most severe form of muscle involvement and may be life-threatening. Guillain-Barrι syndrome is another frequent neuromuscular dengue-associated complication. Dengue-associated Guillain-Barrι syndrome responds very well to intravenous immunoglobulins. Predominant spinal gray matter involvement has been reported in a patient presenting with areflexic paraparesis. Mononeuropathies often manifest with paralysis of the diaphragm due to phrenic nerve dysfunction. Brachial plexopathy, in the form of neuralgic amyotrophy, has been described much more frequently than lumbo-sacral plexopathy. Early recognition of these neuromuscular complications is needed for successful treatment and to prevent further disabilities.

  13. Dengue-associated neuromuscular complications.

    Garg, Ravindra Kumar; Malhotra, Hardeep Singh; Jain, Amita; Malhotra, Kiran Preet


    Dengue is associated with many neurological dysfunctions. Up to 4% of dengue patients may develop neuromuscular complications. Muscle involvement can manifest with myalgias, myositis, rhabdomyolysis and hypokalemic paralysis. Diffuse myalgia is the most characteristic neurological symptom of dengue fever. Dengue-associated myositis can be of varying severity ranging from self-limiting muscle involvement to severe dengue myositis. Dengue-associated hypokalemic paralysis often has a rapidly evolving course; benign nature; excellent response to potassium; and, often leads to diagnostic confusion with other dengue-associated neuromuscular disorders. Rhabdomyolysis is the most severe form of muscle involvement and may be life-threatening. Guillain-Barrι syndrome is another frequent neuromuscular dengue-associated complication. Dengue-associated Guillain-Barrι syndrome responds very well to intravenous immunoglobulins. Predominant spinal gray matter involvement has been reported in a patient presenting with areflexic paraparesis. Mononeuropathies often manifest with paralysis of the diaphragm due to phrenic nerve dysfunction. Brachial plexopathy, in the form of neuralgic amyotrophy, has been described much more frequently than lumbo-sacral plexopathy. Early recognition of these neuromuscular complications is needed for successful treatment and to prevent further disabilities. PMID:26238884

  14. Weak associativity and deformation quantization

    Kupriyanov, V G


    Non-commutativity is quite natural in string theory. For open strings it appears due to the presence of non-vanishing background two-form in the world volume of Dirichlet brane, while in closed string theory the flux compactifications with non-vanishing three-form also lead to non-commutativity. Except for some specific cases, like the constant $B$-field in open strings, the string coordinates are not only non-commutative, but also non-associative. It manifests the non-geometric nature of the consistent string vacua. The aim of this paper is to study the mathematical tools necessary to deal with non-associativity in physics. Working in the framework of deformation quantization we admit non-associative star products, but keep the violation of associativity under control. We require that the star associator of three functions should vanish whenever each two of them are iqual. Such a star product is called alternative. This condition imposes the restriction on non-associative algebras, the star commutator should...

  15. Family-based association tests for genomewide association scans.

    Chen, Wei-Min; Abecasis, Goncalo R


    With millions of single-nucleotide polymorphisms (SNPs) identified and characterized, genomewide association studies have begun to identify susceptibility genes for complex traits and diseases. These studies involve the characterization and analysis of very-high-resolution SNP genotype data for hundreds or thousands of individuals. We describe a computationally efficient approach to testing association between SNPs and quantitative phenotypes, which can be applied to whole-genome association scans. In addition to observed genotypes, our approach allows estimation of missing genotypes, resulting in substantial increases in power when genotyping resources are limited. We estimate missing genotypes probabilistically using the Lander-Green or Elston-Stewart algorithms and combine high-resolution SNP genotypes for a subset of individuals in each pedigree with sparser marker data for the remaining individuals. We show that power is increased whenever phenotype information for ungenotyped individuals is included in analyses and that high-density genotyping of just three carefully selected individuals in a nuclear family can recover >90% of the information available if every individual were genotyped, for a fraction of the cost and experimental effort. To aid in study design, we evaluate the power of strategies that genotype different subsets of individuals in each pedigree and make recommendations about which individuals should be genotyped at a high density. To illustrate our method, we performed genomewide association analysis for 27 gene-expression phenotypes in 3-generation families (Centre d'Etude du Polymorphisme Humain pedigrees), in which genotypes for ~860,000 SNPs in 90 grandparents and parents are complemented by genotypes for ~6,700 SNPs in a total of 168 individuals. In addition to increasing the evidence of association at 15 previously identified cis-acting associated alleles, our genotype-inference algorithm allowed us to identify associated alleles at 4

  16. Hypereosinophilia associated with genital sarcomas

    Eosinophils are phagocytic leukocytes, regulators reactions Mast cell mediated hypersensitivity. toxicity and primarily responsible antiparasitic. Predominate in epithelial tissues near the interface surface (skin, digestive tract) .The cytotoxic reaction exerted by deposit cell surface substances from the granules themselves: peroxidases, neurotoxins, and other cationic proteins. Hypereosinophilia is defined as the increase in eosinophils above 1500 / m m3. The most common causes are parasitic infections and reactions allergic. About 60% of tumors may be associated with an elevation eosinophil discrete but marked eosinophilia in these patients is little frequent. Tumors are most associated lung cancer and tumors hematology. There are few reports of this entity associated with uterine sarcomas. Although the pathophysiologic mechanism is unclear, it is assumed that the base is the increased secretion of cytokines eosinofilopoiétics: interleukins (Il) I L-3, Il-5 and G M-CSFR among other possible. Self-morbidity is primarily maintained hypereosinophilic heart, and is derived from the cytotoxic action, with endomyocardial fibrosis and thrombosis. Treatment should be directed at the control of the underlying disease, as good Tumor response was associated with the account and normalizaciónd eosinófiles. Los corticosteroids prednisone, 60 mg / day po) may be effective because antagonize The stimulatory effect of cytokines. In the vast majority of cases, the disease is associated with hypereosinophilia disseminated and poor overall prognosis We present a case of vaginal sarcoma with pulmonary metastases and hypereosinophilia seniors who responded to treatment with chemotherapy

  17. Forward Association, Backward Association, and the False-Memory Illusion

    Brainerd, C. J.; Wright, Ron


    In the Deese-Roediger-McDermott false-memory illusion, forward associative strength (FAS) is unrelated to the strength of the illusion; this is puzzling, because high-FAS lists ought to share more semantic features with critical unpresented words than should low-FAS lists. The authors show that this null result is probably a truncated range…

  18. Other bioenergy associations in Finland - Wood Energy Association

    The Wood Energy Association (WEA) was founded in August 1994 by seven Finnish organizations to promote wood-based energy production. To achieve the objectives, the association maintains contacts to authorities and organizations in items related to the use of wood fuels, assists members and companies in matter concerning business economics and commercialization. When possible, the WEA participates in research projects as well. WEA acts as an umbrella for wood energy producers, energy consumers and other users of wood energy. The association has also participated in a research project which examined the preconditions to establish a field biomass centre in Finland. Taxation policy is one of the association's key-note issues when promoting wood energy. At present, wood fuels, such as bark, sawmill dust, waste wood and black liquor are used. The largest so far unutilized source of wood energy are chips produced of forest residues from timber felling and chips from thinnings of whole trees. As the most important renewable energy resource commercially viable for large-scale production, wood energy can be made commercially more attractive when district heating and electricity production are combined. There is also a large potential in local heating. The initial position of environmental taxes is to reduce emissions when generating heat and power

  19. Microfibrillar-Associated Protein 4

    Sækmose, Susanne Gjørup; Mössner, Belinda; Christensen, Peer Brehm;


    associations between plasma MFAP4 (pMFAP4) and transient elastography or chronic hepatitis C virus infection in drug users and in a mixed patient cohort with increased risk of liver disease. Moreover, the study aimed to identify comorbidities that significantly influence pMFAP4. METHODS: pMFAP4 was measured in......BACKGROUND AND AIMS: A method for assessment of liver fibrosis and cirrhosis without the need for a liver biopsy is desirable. Microfibrillar-associated protein 4 (MFAP4) is a suggested biomarker for identification of high-risk patients with severe fibrosis stages. This study aimed to examine...... for pMFAP4. Univariate and subgroup analyses were performed using non-parametric methods. RESULTS: pMFAP4 increased significantly with liver fibrosis score. pMFAP4 was significantly associated with chronic viral infection in the drug users and with transient elastography in both cohorts. In the mixed...

  20. Microfibrillar-associated protein 4

    Johansson, Sofie Lock; Roberts, Nassim Bazeghi; Schlosser, Anders;


    BACKGROUND: Microfibrillar-associated protein 4 (MFAP4) is a matricellular glycoprotein that co-localises with elastic fibres and is highly expressed in the lungs. The aim of this study was to test the hypothesis that plasma MFAP4 (pMFAP4) reflects clinical outcomes in chronic obstructive pulmonary...... disease (COPD). METHODS: pMFAP4 was measured by an AlphaLISA immunoassay in stable COPD (n = 69) at baseline and at follow-up until 24 months after inclusion and in acute exacerbations of COPD (AECOPD) (n = 14) at baseline and until 6 months after inclusion. RESULTS: The majority of patients (89%) were in...... GOLD II and III. Multiple linear regressions showed positive associations between pMFAP4 and the Global initiative for Obstructive Lung Disease (GOLD) grade (p = 0.01), modified Medical Research Council score (p < 0.0001) and BODE index (p = 0.04). Negative associations were found with 6-min walking...

  1. The Staff Association and you

    Staff Association


    The Staff Association, your representative with the Management and the Member States The article VII 1.01 of the Staff Rules and Regulations (SR&R) provides that “the relations between the Director-General and the personnel shall be established either on an individual basis or on a collective basis with the Staff Association as intermediary”. This essential role of the Staff representatives, of being the spokesperson of the entire staff of the Organization vis-à-vis the Director-General and the Members States, is achieved through regular participation in the various joint advisory committees defined in the SR&R. The most important are the Standing Concertation Committee and the TREF, tripartite forum where your representatives meet with the Member States delegates, in the presence of the Management, to explain the position of the staff on the various issues concerning employment conditions. The Finance Committee also gives the opportunity to the Staff Association to ...

  2. Dissecting hydrophobic hydration and association.

    Remsing, Richard C; Weeks, John D


    We use appropriately defined short-ranged reference models of liquid water to clarify the different roles local hydrogen bonding, van der Waals attractions, and long-ranged electrostatic interactions play in the solvation and association of apolar solutes in water. While local hydrogen bonding interactions dominate hydrophobic effects involving small solutes, longer-ranged electrostatic and dispersion interactions are found to be increasingly important in the description of interfacial structure around large solutes. The hydrogen bond network sets the solute length scale at which a crossover in solvation behavior between these small and large length scale regimes is observed. Unbalanced long-ranged forces acting on interfacial water molecules are also important in hydrophobic association, illustrated here by analysis of the association of model methane and buckminsterfullerene solutes. PMID:23944226

  3. [Direct oral anticoagulant associated bleeding].

    Godier, A; Martin, A-C; Rosencher, N; Susen, S


    Direct oral anticoagulants (DOAC) are recommended for stroke prevention in atrial fibrillation and for the treatment of venous thromboembolism. However, they are associated with hemorrhagic complications. Management of DOAC-induced bleeding remains challenging. Activated or non-activated prothrombin concentrates are proposed, although their efficacy to reverse DOAC is uncertain. Therapeutic options also include antidotes: idarucizumab, antidote for dabigatran, has been approved for use whereas andexanet alpha, antidote for anti-Xa agents, and aripazine, antidote for all DOAC, are under development. Other options include hemodialysis for the treatment of dabigatran-associated bleeding and administration of oral charcoal if recent DOAC ingestion. DOAC plasma concentration measurement is necessary to guide DOAC reversal. We propose an update on DOAC-associated bleeding, integrating the availability of dabigatran antidote and the critical place of DOAC concentration measurements. PMID:27297642

  4. Observational Calculi and Association Rules

    Rauch, Jan


    Observational calculi were introduced in the 1960’s as a tool of logic of discovery. Formulas of observational calculi correspond to assertions on analysed data. Truthfulness of suitable assertions can lead to acceptance of new scientific hypotheses. The general goal was to automate the process of discovery of scientific knowledge using mathematical logic and statistics. The GUHA method for producing true formulas of observational calculi relevant to the given problem of scientific discovery was developed. Theoretically interesting and practically important results on observational calculi were achieved. Special attention was paid to formulas - couples of Boolean attributes derived from columns of the analysed data matrix. Association rules introduced in the 1990’s can be seen as a special case of such formulas. New results on logical calculi and association rules were achieved. They can be seen as a logic of association rules. This can contribute to solving contemporary challenging problems of data minin...

  5. Rhombencephalitis associated with Dengue fever.

    Verma, Rajesh; Bharti, Kavita; Mehta, Mannan; Bansod, Amrit


    Dengue infection is gradually disseminating throughout the world in alarming proportions. It is a arbovirus infection,transmitted by aedes mosquitoes. It is a multi-systemic disorder associated with varied neurological complications. There is increased trend of development of neurological complications in dengue fever. The neurological complications arising due to dengue infection can be categorized into central and neuromuscular complications. The central nervous system disorders reported with dengue fever are encephalopathy,encephalitis and myelitis.Here we report a case of rhombencephalitis associated with dengue fever. The literature does not mention rhombencephalitis occurring with dengue illness. PMID:27015434

  6. Pattern Discovery Using Association Rules

    Ms Kiruthika M,


    Full Text Available The explosive growth of Internet has given rise to many websites which maintain large amount of user information. To utilize this information, identifying usage pattern of users is very important. Web usage mining is one of the processes of finding out this usage pattern and has many practical applications. Our paper discusses how association rules can be used to discover patterns in web usage mining. Our discussion starts with preprocessing of the given weblog, followed by clustering them and finding association rules. These rules provide knowledge that helps to improve website design, in advertising, web personalization etc.

  7. Hebeloma species associated with Cistus.

    Eberhardt, Ursula; Beker, Henry J; Vila, Jordi; Vesterholt, Jan; Llimona, Xavier; Gadjieva, Rena


    The genus Hebeloma has a number of species highly specific to Cistus and others that occur with several host genera. This paper discusses the species of Hebeloma that appear to be ectomycorrhizal with Cistus, judging from their occurrence when Cistus is the only available host. The previously unknown species H. plesiocistum spec. nov. is described. We also provide a key to the known Hebeloma associates of Cistus. Molecular analyses based on ITS sequence data further illustrate the distinctness of the newly described species and difficulties in the species delimitation with view to H. erumpens. Specific associations with Cistus may have evolved more than once within the genus Hebeloma. PMID:18940258

  8. [Nephrotic syndrome associated with ampulloma].

    López-Navidad, A; Colomina, J; Domingo, P; Franco, M; Algaba, F


    A patient is reported who presented simultaneously classic nephrotic syndrome and adenocarcinoma of the Vater ampulla. Morphological study of the renal biopsy revealed changes characteristic of membranous glomerulonephritis and subepithelial deposits. These deposits stained specifically for IgG and C'3 with a granular pattern, but deposits of CEA-antiCEA immune complexes were not found in glomerular capillaries. The association of nephrotic syndrome with lymphoproliferative diseases and a large variety of solid tumors, like carcinoma of the breast, bronchogenic, colon and stomach has been communicated, but the present case constitutes the first known association with adenocarcinoma of the Vater ampulla. PMID:2772382

  9. Asymptotics for Associated Random Variables

    Oliveira, Paulo Eduardo


    The book concerns the notion of association in probability and statistics. Association and some other positive dependence notions were introduced in 1966 and 1967 but received little attention from the probabilistic and statistics community. The interest in these dependence notions increased in the last 15 to 20 years, and many asymptotic results were proved and improved. Despite this increased interest, characterizations and results remained essentially scattered in the literature published in different journals. The goal of this book is to bring together the bulk of these results, presenting

  10. Montessori Transformation at Computer Associates.

    Mars, Lisa


    Describes the growth of the all-day Montessori program for children ages 6 weeks to 6 years at Computer Associates' corporate headquarters and multiple sites worldwide. Focuses on placement of AMI Montessori-trained teachers, refurbishing of the child development centers to fit Montessori specifications, and the Nido--the children's community--and…

  11. Spectrophotometric determination of association constant

    Spanget-Larsen, Jens


    Least-squares 'Systematic Trial-and-Error Procedure' (STEP) for spectrophotometric evaluation of association constant (equilibrium constant) K and molar absorption coefficient E for a 1:1 molecular complex, A + B = C, with error analysis according to Conrow et al. (1964). An analysis of the Charg...

  12. Spina Bifida Association of America

    Exceptional Parent, 1974


    The Statement of the Spina Bifida Association of America (SBAA) explains SB as a malformation of the central nervous system, reports the formation of SBAA in 1974, explains SBAA's emphasis on local chapter organization, and describes SBAA services, including a bimonthly publication, public education efforts, and research validation projects. (GW)

  13. Congenital anomalies associated with hypothyroidism.

    Bamforth, J S; Hughes, I; Lazarus, J; John, R.


    Seven of the 34 infants identified through the Welsh Hypothyroid Screening Programme have additional congenital abnormalities. Two infants have a previously undescribed syndrome, two have chromosomal abnormalities, two have congenital heart disease, and one has a myelomeningocoele. Congenital hypothyroidism often seems to be associated with other congenital abnormalities.

  14. Brain Injury Association of America

    ... Only) 1-800-444-6443 Welcome to the Brain Injury Association of America (BIAA) Brain injury is not an event or an outcome. ... misunderstood, under-funded neurological disease. People who sustain brain injuries must have timely access to expert trauma ...

  15. Automatic Association of News Items.

    Carrick, Christina; Watters, Carolyn


    Discussion of electronic news delivery systems and the automatic generation of electronic editions focuses on the association of related items of different media type, specifically photos and stories. The goal is to be able to determine to what degree any two news items refer to the same news event. (Author/LRW)

  16. Unveiling new associations in Puppis

    Orsatti, A. M.; Vega, A. M.; Martí nez, R. E.


    A combined photometric and polarimetric analysis of OB stars known from two searches of OB stars in the Puppis region resulted in the identification of a new OB association located at a distance of 2.6 kpc from the Sun and with a main concentration at l=249fdg 3, b=-4fdg 6. There is another young group at a greater distance (4.4 kpc) that partially overlaps the first one on the (l,b) plane. The polarization efficiency of the dust towards the association is very low (1.25). The parameters of the ISM in the central region of the association are P_V=1.21± 0.18(%) and theta_V=140fdg 2± 3fdg 3; the dust grains are of normal size, similar to the mean for the ISM (0.55 μm). We discuss the location of both groups and propose the OB association as part of the local arm, while the other group would be part of the Perseus arm, according to the four-arm model of Hou & Han.

  17. Antibiotic associated diarrhoea: Infectious causes

    Ayyagari A


    Full Text Available Nearly 25% of antibiotic associated diarrhoeas (AAD is caused by Clostridium difficile, making it the commonest identified and treatable pathogen. Other pathogens implicated infrequently include Clostridium perfringens, Staphylococcus aureus, Klebsiella oxytoca, Candida spp. and Salmonella spp. Most mild cases of AAD are due to non-infectious causes which include reduced break down of primary bile acids and decrease metabolism of carbohydrates, allergic or toxic effects of antibiotic on intestinal mucosa and pharmacological effect on gut motility. The antibiotics most frequently associated with C. difficile associated diarrhoea are clindamycin, cephalosporin, ampicillin and amoxicillin. Clinical presentation may vary from mild diarrhoea to severe colitis and pseudomembranous colitis associated with high morbidity and mortality. The most sensitive and specific diagnostic test for C. difficile infection is tissue culture assay for cytotoxicity of toxin B. Commercial ELISA kits are available. Though less sensitive, they are easy to perform and are rapid. Withdrawal of precipitating antibiotic is all that is needed for control of mild to moderate cases. For severe cases of AAD, oral metronidazole is the first line of treatment, and oral vancomycin is the second choice. Probiotics have been used for recurrent cases.

  18. Association between attachment and schizotypy

    Dunne, Colm


    Background: The human genome project has affirmed the importance of non-genetic factors in human development. Attachment style is considered to be a diathesis for psychopathology and an important determinant regarding interpersonal functioning. Epidemiological research has indicated that there is significant aetiological continuity between symptoms of schizotypy and clinical symptoms of schizophrenia. Limited research has investigated the association between attachment and schi...


    Rolly Intan


    Full Text Available Association rules that involve two or more dimensions or predicates can be referred as multidimensional association rules. Rather than searching for frequent itemsets (as is done in mining single-dimensional association rules, in multidimensional association rules, we search for frequent predicate sets. In general, there are two types of multidimensional association rules, namely interdimension association rules and hybrid-dimension association rules. Interdimension association rules are multidimensional association rules with no repeated predicates. This paper introduces a method for generating interdimension association rules. A more meaningful association rules can be provided by generalizing crisp value of attributes to be fuzzy value. To generate the multidimensional association rules implying fuzzy value, this paper introduces an alternative method for mining the rules by searching for the predicate sets.

  20. Associativity and normative credal probability.

    Snow, P


    Cox's Theorem is a widely cited motivation for probabilistic models of uncertain belief. The theorem relates the associativity of the logical connectives to that of the arithmetic operations of probability. Recent questions about the correctness of Cox's Theorem have been resolved, but there are new questions about one functional equation used by Cox in 1946. This equation is missing from his later work. Advances in knowledge since 1946 and changes in Cox's research interests explain the equation's disappearance. Other associativity-based motivations avoid functional equations altogether, and so may be more transparently applied to finite domains and discrete beliefs. A discrete counterpart of Cox's Theorem can be assembled from results that have been in the literature since 1959. PMID:18238098

  1. Association theories for complex thermodynamics

    Kontogeorgis, Georgios; Rafiqul Gani


    promising direction for a general and useful for engineering purposes modeling of complex thermodynamics is via the use of association theories e.g. those based on chemical theory (like APACT), or on the lattice theory (like NRHB) or those based on perturbation theory (like SAFT and CPA). The purpose of......Thermodynamics of complex systems (e.g. with associating molecules, multicomponent mixtures, multiphase equilibria, wide ranges of conditions, estimation of many different properties simultaneously) is a topic of great importance in chemical engineering and for a wide range of industrial...... applications. While specialized models can handle different cases, even complex ones, with the advent of powerful theories and computers there is the hope that a single or a few models could be suitable for a general modeling of complex thermodynamics. After more than 100 years with active use of thermodynamic...

  2. Association between Frailty and Dementia

    Kulmala, J; Nykänen, I; Mänty, Minna Regina;


    of the participants was assessed using the Cardiovascular Health Study criteria. Cognitive function was assessed with the Mini-Mental State Examination (MMSE). Clinically diagnosed dementia was assessed by specialists using diagnostic criteria. The associations between frailty and cognition were investigated using...... logistic regression. Results: A total of 93 (14%) participants were classified as frail. Cognitive impairment (MMSE score disease, 19 (3%) had vascular dementia, 12 (2%) had.......0-15.9), almost 6 times more likely to have vascular dementia (OR 5.6, 95% CI 1.2-25.8) and over 4 times more likely to have Alzheimer's disease (OR 4.5, 95% CI 2.1-9.6) than persons who were robust. Conclusion: Frailty is strongly associated with cognitive impairment and clinically diagnosed dementia among...

  3. Radiation-Associated Kidney Injury

    The kidneys are the dose-limiting organs for radiotherapy to upper abdominal cancers and during total body irradiation. The incidence of radiotherapy-associated kidney injury is likely underreported owing to its long latency and because the toxicity is often attributed to more common causes of kidney injury. The pathophysiology of radiation injury is poorly understood. Its presentation can be acute and irreversible or subtle, with a gradual progressive dysfunction over years. A variety of dose and volume parameters have been associated with renal toxicity and are reviewed to provide treatment guidelines. The available predictive models are suboptimal and require validation. Mitigation of radiation nephropathy with angiotensin-converting enzyme inhibitors and other compounds has been shown in animal models and, more recently, in patients.

  4. Osteogenesis imperfecta: an atypical association

    Snehal Mallakmir


    Full Text Available Osteogenesis Imperfecta (OI also known as and lsquo;brittle bone disease', is a clinically heterogeneous connective tissue disorder with defect in type I collagen. The more prevalent autosomal dominant forms of OI are caused by primary defects in type I collagen, while autosomal recessive forms are caused by deficiency of proteins which interact with type I procollagen for post-translational modification and/or folding. Few cases of OI associated with atypical features have been reported. We report a case of 54 days male child of OI associated with pyloric stenosis. The case probably is a form of autosomal recessive OI with severe phenotype. [Int J Res Med Sci 2015; 3(3.000: 783-785

  5. Polynomials Associated with Dihedral Groups

    Charles F. Dunkl


    Full Text Available There is a commutative algebra of differential-difference operators, with two parameters, associated to any dihedral group with an even number of reflections. The intertwining operator relates this algebra to the algebra of partial derivatives. This paper presents an explicit form of the action of the intertwining operator on polynomials by use of harmonic and Jacobi polynomials. The last section of the paper deals with parameter values for which the formulae have singularities.

  6. Bacterial Associations: Antagonism to Symbiosis

    Nair, S.

    of gene exchange to produce diversity of genotype and thus this enduring coevolutionary history shared by symbiotic partners has resulted in a major evolutionary transition: a symbiont?s loss of independent growth, and possibly also the sexual phase of its... partnerships between entirely separate organisms. The article examines some examples of interactions at different levels of associations. The marine environment is the abode of many groups of organisms and also is a complex milieu of interactions among many...

  7. EGAN: exploratory gene association networks

    Paquette, Jesse; Tokuyasu, Taku


    Summary: Exploratory Gene Association Networks (EGAN) is a Java desktop application that provides a point-and-click environment for contextual graph visualization of high-throughput assay results. By loading the entire network of genes, pathways, interactions, annotation terms and literature references directly into memory, EGAN allows a biologist to repeatedly query and interpret multiple experimental results without incurring additional delays for data download/integration. Other compelling...

  8. Clostridium difficile-associated colitis.

    Hull, Mark W.; Beck, Paul L


    OBJECTIVE: To review the basic microbiology, pathogenesis of disease, and diagnosis of the nosocomial pathogen Clostridium difficile and to examine therapies recommended by the Canadian Task Force on Preventive Health Care. QUALITY OF EVIDENCE MEDLINE: was searched using MeSH headings. Controlled trials for therapy were sought, but case-control studies and observational reviews were included. MAIN MESSAGE: Clostridium difficile causes approximately 20% of cases of diarrhea associated with ant...

  9. Pantothenate Kinase-Associated Neurodegeneration

    Meitinger, Thomas; Prokisch, Holger; Hartig, Monika B.; Klopstock, Thomas


    Pantothenate kinase-associated neurodegeneration (PKAN) is a hereditary progressive disorder and the most frequent form of neurodegeneration with brain iron accumulation (NBIA). PKAN patients present with a progressive movement disorder, dysarthria, cognitive impairment and retinitis pigmentosa. In magnetic resonance imaging, PKAN patients exhibit the pathognonomic "eye of the tiger" sign in the globus pallidus which corresponds to iron accumulation and gliosis as shown in neuropathological e...

  10. Sweet syndrome associated with interferon

    Rodriguez-Lojo, Romina; Castineiras, Iria; Juarez, Yolanda; Lueiro, Mercedes; Armesto, Ana; Fernandez-Diaz, M. Luisa


    Although still very rare, drug-related cases of Sweet’s syndrome have been reported. The more frequent associated medications with drug induced Sweet´s syndrome was: tetracyclines, trimethoprim-sulphamethaxazol, azatioprine, all trans retinoic acid, nitrofurantoin, granulocyte colony-stimulating factor, hydralazine, tripharil, lithium, oral contraceptives, furosemide, celecoxib and azathioprine. We only found one case of drug-induced Sweet´s syndrome secondary to pegylated interferon...

  11. Pseudogap associated with precursor pairing

    De Cao, Tian


    This work argues that the off-diagonal long range order (ODLRO) is not necessary for showing superconductivity while the electron pairing around Fermi surface is sufficient for superconductivity. It is shown that there exists the pseudogap state associated with the electron pairing in real space and the high temperature superconductivity could be only found in the metallic region near the Mott metal insulator transition (MIT).

  12. Stimulus control and associative learning.

    Williams, B. A.


    Interest in operant research on stimulus control has declined at the same time that much interest has burgeoned in nonoperant areas. Several examples of this shift toward traditional learning theory are considered, all of which have sponsored theoretical approaches that attempt to characterize the underlying associative units. These theoretical approaches are defended on the grounds that they have generated a deeper understanding of a variety of often puzzling phenomena. My projection is that...

  13. Antibiotic associated diarrhoea: Infectious causes

    Ayyagari A; Agarwal J; Garg A


    Nearly 25% of antibiotic associated diarrhoeas (AAD) is caused by Clostridium difficile, making it the commonest identified and treatable pathogen. Other pathogens implicated infrequently include Clostridium perfringens, Staphylococcus aureus, Klebsiella oxytoca, Candida spp. and Salmonella spp. Most mild cases of AAD are due to non-infectious causes which include reduced break down of primary bile acids and decrease metabolism of carbohydrates, allergic or toxic effects of antibiotic ...

  14. Molecular Mechanisms Underlying Associative Learning

    Koekkoek, Bas


    textabstractThis thesis primarily attempts to solve some long standing issues regarding classical eyelid conditioning. More specifically, what is the specific role of cerebellar LTD in classical eyeblink conditioning, and how does the answer change the view on cerebellar functioning on associative motor learning. The approach used in this thesis is a combination of the above mentioned genetic approach with classical conditioning experiments. The genetic techniques are by far best possible in mi...

  15. Psoriasis and Associated Psychiatric Disorders

    Abreu, José Luís Pio Da Costa; Reis, José Pedro Gaspar Dos; Figueiredo, Américo Manuel Da Costa


    Introduction and objective: Psoriasis is a chronic skin disease with a high impact on self-esteem and patients’ health-related quality of life. In the last decades some studies have pointed out mental disorders associated with psoriasis and the etiopathogenic mechanisms behind that co-existence. This work compiles psychopathology associated with psoriasis and further analyzes the etiopathogenesis of psoriasis and mental disorders. Methods: A systematic review of the literature was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and using the “5S” levels of organization of evidence from healthcare research, as previously described. Results: Psoriasis is linked with many mental disorders, both in the psychotic and neurotic sprectrum. Chronic stress diminishes hypothalamic-pituitary-adrenal axis and upregulates sympathetic-adrenal-medullary responses, stimulating pro-inflammatory cytokines. Then, it maintains and exacerbates psoriasis and some of its mental disorders. High levels of pro-inflammatory cytokines connect psoriasis, psychiatric conditions, and other comorbidities of psoriasis (such as atherosclerosis) within a vicious cycle. Furthermore, the etiopathogenesis of the link between each psychiatric comorbidity and psoriasis has its own subtleties, including the cooccurrence of other comorbidities, the parts of the body affected by psoriasis, treatments, and biological and psychosocial factors. Conclusion: The study of psychopathology can amplify our understanding about the etiopathogenesis of psoriasis and associated mental disorders. Patients would benefit from a psychodermatologic approach. The adequate treatment should take into account the mental disorders associated with psoriasis as well as the circumstances under which they occur.

  16. Angioneurotic Edema Associated with Haloperidol

    Samrina Kahlon; Cathy Lee; Roger Chirurgi; Getaw Worku Hassen


    Background. Angioneurotic edema is a life-threatening medical emergency that requires urgent diagnosis and treatment. Haloperidol is in the butyrophenone class of antipsychotic medications. Acute anaphylaxis to Haloperidol is very rare and no cases have been reported in literature. Objective. To report the association of life-threatening angioneurotic edema with intramuscular Haloperidol. Case Report. We present a case of an adult with no known allergies in whom angioneurotic edema with tongu...

  17. Dissecting Hydrophobic Hydration and Association

    Remsing, Richard C.; Weeks, John D.


    We use appropriately defined short ranged reference models of liquid water to clarify the different roles local hydrogen bonding, van der Waals attractions, and long ranged electrostatic interactions play in the solvation and association of apolar solutes in water. While local hydrogen bonding in- teractions dominate hydrophobic effects involving small solutes, longer ranged electrostatic and dis- persion interactions are found to be increasingly important in the description of interfacial st...

  18. Achondroplasia Associated with Bilateral Keratoconus

    Samar A. Al-Swailem; Al Bin Ali, Ghada Y.; Al Katan, Hind M.; Al Mahmood, Ammar M.


    We report a rare case of bilateral keratoconus in association with achondroplasia. A 26-year-old male, with a known case of achondroplasia, complained of bilateral gradual deterioration in vision for the past few years. Slit lamp biomicroscopy showed bilateral central corneal protrusion and stromal thinning at the apex consistent with keratoconus. a trial of hard contact lens fitting failed to improve VA in the left eye (LE). Right eye (RE) improved to 20/25. The patient underwent penetrating...

  19. Variables Associated with Export Profitability

    Warren J Bilkey


    This study is an analysis of variables associated with the profitability of exporting. Such information is useful both for export management and for government agencies that wish to promote business commitment of exporting. The methodology utilizes a multiple regression analysis of data in questionnaire responses from 168 Wisconsin manufacturing firms in 1979. It provides a means for evaluating difficult-to-measure export marketing considerations (such as, export marketing channels, export me...

  20. Lithium-Associated Kidney Microcysts

    Jennifer Tuazon; David Casalino; Ehteshamuddin Syed; Daniel Batlle


    Long-term lithium therapy is associated with impairment in concentrating ability and, occasionally, progression to advanced chronic kidney disease from tubulointerstitial nephropathy. Biopsy findings in patients with lithium-induced chronic tubulointerstitial nephropathy include tubular atrophy and interstitial fibrosis interspersed with tubular cysts and dilatations. Recent studies have shown that cysts are seen in 33––62.5% of the patients undergoing lithium therapy. MR imaging is highly ca...

  1. Histograms and Associated Point Processes

    Jacob, Pierre; Oliveira, Paulo


    Non parametric inference for point processes is approached using histograms, which provide a nice tool for the analysis of on-line data. The construction of histograms depend on a sequence of partitions, which we take to be non embedded. This is quite natural in what regards applications, but presents some theoretical problems. On another direction, we drop the usual independence assumption on the sample, replacing it by an association hypothesis. Under this setting, we study t...

  2. Communicable diseases associated with water

    The diseases associated with contaminated water remain among the most serious public health problems for much of the world's population living in developing countries. Most of the disease agents that contaminated water and food are biological and come from animal or human faeces. They include bacteria, viruses, protozoa and helminths and multiply in the alimentary tract and are excreted with the faeces. Without proper sanitation they find their way into other water bodies from where they can infect other people. Most of the diseases associated with water are communicable. According to Bradley the diseases associated with water can be classified in four categories: waterborne water-washed, water-based and water related and a fifth category emerging in developed countries could be called water-dispersed. The experiences of these diseases in various in various parts of Pakistan and the role played by National Institute of Health (NIH) in investigation will be discussed: some of them being hepatitis E epidemic in Islamabad (1993,94,95), experience at Nawabshah and some others will be discussed in detail along with their preventive and control measures. (author)

  3. Why join the Staff Association

    Association du personnel


    Becoming a member of the Staff Association (SA) is above all a personal choice, showing that the joining person’s commitment and adherence to values such as solidarity, social cohesion, etc.In September, the SA launches a membership campaign to convince a maximum number to join, to inform, arouse interest and support. Posters, emails and individual contacts are part of the campaign programme, just like this editorial. As far as individual contacts are concerned, we ask you to give time and lend an ear to the delegates of your department in the Staff Council, who will approach you, in order to make an open and constructive discussion possible. Do not hesitate to ask questions and let them know your thoughts about the SA, as (constructive) criticism enables us to progress. The Staff Association and its role of collective representation The Staff Association, via its delegates, represents collectively all staff of the Organization before the Director-General and Member States. To do this, staff rep...

  4. Are cataracts associated with osteoporosis?

    Nemet AY


    Full Text Available Arie Y Nemet,1 Joel Hanhart,2 Igor Kaiserman,3,4 Shlomo Vinker5,6 1Department of Ophthalmology, Meir Medical Center, Kfar Saba, 2Department of Ophthalmology, Shaare Zedek Medical Center, Jerusalem, 3Department of Ophthalmology, Barzilai Medical Center, Ashkelon, 4Faculty of Health Sciences, Ben Gurion University, Be'er Sheba, 5Department of Family Medicine, Clalit Health Services, Rehovot, 6Department of Family Medicine, Tel Aviv University, Tel Aviv, Israel Background: Calcium is considered an important factor in the development of both osteoporosis and cataract. This study evaluated the association between osteoporosis and cataracts. Objective: To evaluate the prevalence of osteoporosis among patients undergoing cataract surgery, and the association between the two. Patients and methods: This was a retrospective observational case-control study, conducted in the Central District of Clalit Health Services (a district of the largest health maintenance organization in Israel. All Clalit members in the district older than 50 years who underwent cataract surgery from 2000 to 2007 (n=12,984 and 25,968 age- and sex-matched controls comprised the sample. Electronic medical records of all patients in the study were reviewed. The main outcome measure was the prevalence of osteoporosis and the odds ratio of having osteoporosis among cataract patients compared with controls. Results: Demographically, 41.8% were men with a mean age of 68.7 ± 8.2 years. A logistic regression model for osteoporosis showed that age, female sex, higher socioeconomic class, smoking, chronic renal failure, hyperthyroidism, rheumatoid arthritis, inflammatory bowel diseases, and cataract are all associated with increased prevalence of osteoporosis. Obesity is a protective factor for osteoporosis. In all age-groups, osteoporosis was more prevalent in cataract patients than in the control group. Conclusion: Among other well-known risk factors, osteoporosis is associated with the

  5. Covariance Association Test (CVAT) Identifies Genetic Markers Associated with Schizophrenia in Functionally Associated Biological Processes

    Rohde, Palle Duun; Demontis, Ditte; Castro Dias Cuyabano, Beatriz;


    Schizophrenia is a psychiatric disorder with large personal and social costs, and understanding the genetic etiology is important. Such knowledge can be obtained by testing the association between a disease phenotype and individual genetic markers; however, such single-marker methods have limited...... power to detect genetic markers with small effects. Instead, aggregating genetic markers based on biological information might increase the power to identify sets of genetic markers of etiological significance. Several set test methods have been proposed: Here we propose a new set test derived from...... among the top performers. When extending CVAT to utilize a mixture of SNP effects, we found an increase in power to detect the causal sets. Applying the methods to a Danish schizophrenia case–control data set, we found genomic evidence for association of schizophrenia with vitamin A metabolism and...

  6. Cancer-associated lysosomal changes

    Kallunki, T; Olsen, O D; Jaattela, Marja


    Rapidly dividing and invasive cancer cells are strongly dependent on effective lysosomal function. Accordingly, transformation and cancer progression are characterized by dramatic changes in lysosomal volume, composition and cellular distribution. Depending on one's point of view, the cancer......-targeting anti-cancer drugs. In this review we compile our current knowledge on cancer-associated changes in lysosomal composition and discuss the consequences of these alterations to cancer progression and the possibilities they can bring to cancer therapy.Oncogene advance online publication, 9 July 2012; doi...

  7. Hypersensitivity reaction associated with phenytoin.

    Indu, T H; Basutkar, Roopa Satyanarayan


    Hypersensitivity reactions with antiepileptic drugs (AEDs) are generally associated with aromatic AEDs. We present a case of hypersensitivity reactions followed by administration of phenytoin with diazepam and ranitidine in a patient with generalized tonic-clonic seizures. Antigen-antibody reactions or decreased levels of epoxide hydrolase are well known with phenytoin. Increased level of serum phenytoin causing toxicities due to competitive inhibition with diazepam on co-administration was also reported in the literature. Prevention of the adverse effects with AEDs is a multi-stage process, which requires implementation of preventive measures through careful monitoring and prompts interventions. PMID:26692739

  8. Idiosyncratic Pancreatitis Associated with Perindopril

    Giuseppe Famularo; Giovanni Minisola; Giulio Cesare Nicotra; Claudio De Simone


    The use of angiotensin-converting enzyme (ACE) inhibitors is not associated with an increased risk of acute pancreatitis [1] and, so far, only one case has been linked with the use of perindopril [2]. We report on a second patient with perindopril-induced pancreatitis. A 72-year-old man presented with a 10-day history of nausea, vomiting, and constant pain in the epigastrium which radiated to the sides. Four weeks before admission, perindopril (4 mg/day) had been added to the usual regimen of...

  9. Associative programming language and virtual associative access manager

    Price, C.


    APL provides convenient associative data manipulation functions in a high level language. Six statements were added to PL/1 via a preprocessor: CREATE, INSERT, FIND, FOR EACH, REMOVE, and DELETE. They allow complete control of all data base operations. During execution, data base management programs perform the functions required to support the APL language. VAAM is the data base management system designed to support the APL language. APL/VAAM is used by CADANCE, an interactive graphic computer system. VAAM is designed to support heavily referenced files. Virtual memory files, which utilize the paging mechanism of the operating system, are used. VAAM supports a full network data structure. The two basic blocks in a VAAM file are entities and sets. Entities are the basic information element and correspond to PL/1 based structures defined by the user. Sets contain the relationship information and are implemented as arrays.

  10. HIV-associated neurocognitive disorders.

    Sanmarti, Montserrat; Ibáñez, Laura; Huertas, Sonia; Badenes, Dolors; Dalmau, David; Slevin, Mark; Krupinski, Jerzy; Popa-Wagner, Aurel; Jaen, Angeles


    Currently, neuropsychological impairment among HIV+ patients on antiretroviral therapy leads to a reduction in the quality of life and it is an important challenge due to the high prevalence of HIV-associated neurocognitive disorders and its concomitant consequences in relation to morbidity and mortality- including those HIV+ patients with adequate immunological and virological status. The fact that the virus is established in CNS in the early stages and its persistence within the CNS can help us to understand HIV-related brain injury even when highly active antiretroviral therapy is effective. The rising interest in HIV associated neurocognitive disorders has let to development new diagnostic tools, improvement of the neuropsychological tests, and the use of new biomarkers and new neuroimaging techniques that can help the diagnosis. Standardization and homogenization of neurocognitive tests as well as normalizing and simplification of easily accessible tools that can identify patients with increased risk of cognitive impairment represent an urgent requirement. Future efforts should also focus on diagnostic keys and searching for useful strategies in order to decrease HIV neurotoxicity within the CNS. PMID:25945248

  11. Random Distances Associated with Rhombuses

    Zhuang, Yanyan


    Parallelograms are one of the basic building blocks in two-dimensional tiling. They have important applications in a wide variety of science and engineering fields, such as wireless communication networks, urban transportation, operations research, etc. Different from rectangles and squares, the coordinates of a random point in parallelograms are no longer independent. As a case study of parallelograms, the explicit probability density functions of the random Euclidean distances associated with rhombuses are given in this report, when both endpoints are randomly distributed in 1) the same rhombus, 2) two parallel rhombuses sharing a side, and 3) two rhombuses having a common diagonal, respectively. The accuracy of the distance distribution functions is verified by simulation, and the correctness is validated by a recursion and a probabilistic sum. The first two statistical moments of the random distances, and the polynomial fit of the density functions are also given in this report for practical uses.

  12. Diseases associated with leaky hemichannels

    Retamal, Mauricio A.; Reyes, Edison P.; García, Isaac E.; Pinto, Bernardo; Martínez, Agustín D.; González, Carlos


    Hemichannels (HCs) and gap junction channels (GJCs) formed by protein subunits called connexins (Cxs) are major pathways for intercellular communication. While HCs connect the intracellular compartment with the extracellular milieu, GJCs allow the interchange of molecules between cytoplasm of two contacting cells. Under physiological conditions, HCs are mostly closed, but they can open under certain stimuli allowing the release of autocrine and paracrine molecules. Moreover, some pathological conditions, like ischemia or other inflammation conditions, significantly increase HCs activity. In addition, some mutations in Cx genes associated with human diseases, such as deafness or cataracts, lead to the formation of more active HCs or “leaky HCs.” In this article we will revise cellular and molecular mechanisms underlying the appearance of leaky HCs, and the consequences of their expression in different cellular systems and animal models, in seeking a common pattern or pathological mechanism of disease. PMID:26283912

  13. Corneal amyloidosis associated with keratoconus.

    Stern, G A; Knapp, A; Hood, C I


    Nodular, gray-white, central corneal opacities which extended from the subepithelial zone through the anterior four fifths of the stroma developed in a 50-year-old man with a longstanding history of hard contact lens wear for keratoconus. Results of histopathologic analysis of the corneal button obtained at the time of penetrating keratoplasty disclosed that the opacities were composed of amyloid. Corneal amyloidosis is rarely found in association with keratoconus. Although there were some similarities in the pattern of amyloid deposition to that seen in primary familial amyloidosis of the cornea, the authors believe that their patient is more likely to have had a secondary amyloidosis. Corneal amyloidosis should be considered in keratoconus patients with development of unusual forms of central corneal opacification. PMID:3278260

  14. Tilings and associated relational structures

    Oger, Francis


    In the present paper, as we did previously in [5], we investigate the relations between the geometric properties of tilings and the algebraic and model-theoretic properties of associated relational structures. Our study is motivated by the existence of aperiodic tilings. In [5], we considered tilings of the euclidean spaces of finite dimension, and isomorphism was defined up to translation. Here, we consider, more generally, tilings of a metric space, and isomorphism is defined modulo an arbitrary group of isometries. The results of Sections 1 and 2 concern, in particular, the characterization of relational structures which can be represented by tilings of some given type, local isomorphism and the extraction preorder. In Section 3, we show that the notions of periodicity and invariance through a translation, defined for tilings of the euclidean spaces of finite dimension, can be generalized, with appropriate hypotheses, to relational structures, and in particular to tilings of non-euclidean spaces. In Sectio...

  15. Gastrointestinal lesions associated with spondyloarthropathies

    Ambrogio Orlando; Sara Renna; Giovanni Perricone; Mario Cottone


    Subclinical gut inflammation has been described in up to two-thirds of patients with spondyloarthropathies (SpA). Arthritis represents an extra-intestinal manifestation of several gastrointestinal diseases,including inflammatory bowel disease (IBD), Whipple's disease, Behcet's disease, celiac disease, intestinal bypass surgery, parasitic infections of the gut and pseudomembranous colitis. Moreover about twothirds of nonsteroidal anti-inflammatory drug users demonstrate intestinal inflammation. Arthritis may manifest as a peripheral or axial arthritis. The spondyloarthropathy family consists of the following entities:ankylosing spondylitis, undifferentiated spondyloar thr i t is, react ive ar thr i t is, psor iat i c arthritis, spondyloarthritis associated with IBD,juvenile onset spondyloarthritis. This topic reviews the major gastrointestinal manifestations that can occur in patients with SpA and in nonsteroidal antiinflammatory drugs users.

  16. Costs Associated With Residency Training.

    Bready, Lois L; Luber, M Philip


    Texas needs more physicians to care for a rapidly growing population, and new physicians who complete medical training in Texas are likely to remain in the state to practice. The expansion of existing Texas medical schools, along with the development of new schools, has created a need for a corresponding increase in residency and fellowship (graduate medical education, or GME) positions in Texas, and the 2013 and 2015 legislative sessions have funded expanded GME support. While the Centers for Medicare & Medicaid Services pays for the majority of GME positions nationally, those numbers were capped in 1997. Growing populations, particularly in the southern states, have led many institutions--when funds are available--to increase GME positions "over the cap." Texas physicians need to be aware of costs associated with development of accredited GME positions, as well as other measures being taken to support the growth of the physician workforce in the state. PMID:26859373

  17. Significant variables associated with epilepsy

    Objective: To study the characteristics of the epileptics and the risk factors contributing to the development of epilepsy. Results: Majority of the subjects were single (77.84%), 1st born among their siblings (25.95%), belonged to low social class (50.63%), and unemployed(25.31%). The major risk factors were family history of illness (23.52%) and positive medical problem around birth (12.66%). The presence of family history of illness, positive medical problem around birth and advanced maternal age at birth were associated with early onset of epilepsy. Vulnerability for the epilepsy also increases among hospital deliveries. Conclusion: Although the present study has identified various risk factors, yet the results need to be further confirmed through case-control studies. (author)

  18. European Nuclear Education Network Association

    Regarding nuclear engineering education in Europe, indicators like declining university enrolment, changing industry personnel profiles, dilution of university course content, and high retirement expectations show that future of nuclear technology expertise seems at risk (OECD/NEA 2000). The European Nuclear Education Network (ENEN), started as a project under the fifth framework programme (FP5) of the European Commission in January 2002. It established the basis for conserving nuclear knowledge and expertise, created a European High Education Area for nuclear disciplines, and initiated the implementation of the Bologna declaration in nuclear disciplines. Pursuing the sustainability of the concept, the ENEN partners organized themselves into a non-profitable legal association called ENEN, in 2003 under the French law of 1901. The first general assembly was held on 11 November 2003 in Luxemburg, with representatives from the European Commission, the Nuclear Energy Agency of the Organization of Economic Cooperation and Development and the International Atomic Energy Agency

  19. [Cystic fibrosis and associated complications].

    Schwarz, C; Staab, D


    Cystic fibrosis (CF) is an autosomal recessive inherited metabolic disease. The mutation is located on the long arm of chromosome 7. Due to a defect in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, chloride ion transport is reduced across the cell membrane. As a result, the disease can be described as an exocrinopathy. In all organs with exocrine glands, disorders occur in association with the defective chloride transport. The main impact of this defect is manifested in the lungs. Therefore, the most common cause of death is pulmonary disease with respiratory insufficiency due to recurrent infections. Unfortunately, a cure for the disease is still not available. However, new therapies that may affect the CFTR mutation more specifically give new hope for better therapeutic options in the future. The long-term goal of therapy is to develop a causal therapy for all six different mutation classes and thus for about 2000 mutations. PMID:25693903

  20. Obesity associated noncommunicable disease burden

    Jyoti Bala Banjare


    Full Text Available World is facing rapid transition in health sector for under nutrition and over nutrition. Obesity is a challenging epidemic and increased Body Mass Index (BMI influences on almost all body systems leading to development of non-communicable diseases. Chronic but slow growing non-infectious pathology of body organization give upsurge onset of non-communicable disorders. Obesity related Non-communicable diseases (NCDs leads to millions of deaths all around the world, rapidly becoming economic burden worldwide. Pathophysiology and extend of obesity is responsible for ill effects of health. In obesity Low grade Inflammation and antioxidant disproportion plays vital role in development of NCDs. Effective health education, professional counselling from public health authorities, free health care, and social insurance can be effective in controlling growing non communicable disease globally. The present analysis attempts to study association of obesity with different NCDs in terms of prevalence and underlying mechanisms.

  1. Association between competing interests and authors' conclusions

    Kjaergard, Lise L; Als-Nielsen, Bodil


    To assess the association between competing interests and authors' conclusions in randomised clinical trials.......To assess the association between competing interests and authors' conclusions in randomised clinical trials....

  2. Characterization of melanoma associated spongiform scleropathy

    Alyahya, Ghassan Ayish Jabur; Heegaard, Steffen; Prause, J.U.

    ophthalmology, melanoma associated spongiform scleropathy (MASS), MASS, malignant uveal melanoma, sclera, ciliary body, choroid, histopathology......ophthalmology, melanoma associated spongiform scleropathy (MASS), MASS, malignant uveal melanoma, sclera, ciliary body, choroid, histopathology...

  3. 7 CFR 1219.2 - Association.


    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.2 Association. Association means an avocado organization established by State statute in a State with...

  4. 7 CFR 1219.58 - Importer associations.


    ... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Budgets, Expenses, and Assessments § 1219.58 Importer associations. (a) An association of avocado importers is eligible to...

  5. Introducing the Australian Uranium Association

    The Australian Uranium Association was formed in September last year in the midst of a very exciting period of change for the industry. What forged this new grouping was the industry's belief that it needed a strong representative organisation to play an advocacy role for uranium exploration and mining, at a very important moment of opportunity for the industry. That 'moment of opportunity' was the result of some critical trends and events, First, the very rapid increase in the price of uranium was driving renewed exploration and investment across Australia and the world. In the previous twelve months, the spot price of uranium had risen more than 90%. Second, the Federal Government had established the Uranium Industry Framework as a means by which government and industry could discuss a better regulatory framework. This led to some very fruitful interchanges between industry players. While the UIF talks were continuing, the Federal Government announced a parallel inquiry into whether Australia ought to move further into the nuclear power cycle. Third, the new interest in Australia in climate change and greenhouse gas emissions had led to a steep increase in public interest in the nuclear power option, with many former opponents now willing to listen to the argument

  6. Ketamine-snorting associated cystitis.

    Chen, Chung-Hsien; Lee, Ming-Huei; Chen, Yi-Chang; Lin, Ming-Fong


    Ketamine hydrochloride, commonly used as a pediatric anesthetic agent, is an N-methyl-D-aspartic (NMDA) acid receptor antagonist with rapid onset and short duration of action. It produces a cataleptic-like state where the patient is dissociated from the surrounding environment by direct action on the cortex and limbic system. It has emerged as an increasingly popular choice among young drug users, especially within dance club venues. Cases of bladder dysfunction among recreational ketamine users were reported since Shahani et al first reported nine cases of ketamine-associated ulcerative cystitis in 2007. We report on four patients who had history of ketamine abuse, presenting with dysuria, fluctuating lower urinary tract symptoms (LUTS), lower abdominal or perineal pain, and impaired functional bladder capacities. Urinalysis showed pyuria and microhematuria. Urine culture was sterile. Bladder ulceration with severe diffuse hemorrhage and low bladder capacity were noted under anesthetized cystoscopic examination. Transurethral bladder mucosa biopsy was consistent with chronic cystitis. Cessation of ketamine abuse was the milestone of treatment, followed by the administration of mucosal protective agents, such as pentosan polysulphate or hyaluronic acid. Suprapubic pain was improved in three patients during follow-up. However, the outcome of treatment depends on the severity of the disease process, similar to that of interstitial cystitis (IC). PMID:22248834

  7. Association studies in consanguineous populations

    Genin, E.; Clerget-Darpous, F. [Institut National d`Etudes Demographiques, Paris (France)


    To study the genetic determinism of multifactorial diseases in large panmictic populations, a strategy consists in looking for an association with markers closely linked to candidate genes. A distribution of marker genotypes different in patients and controls may indicate that the candidate gene is involved in the disease. In panmictic populations, the power to detect the role of a candidate gene depends on the gametic disequilibrium with the marker locus. In consanguineous populations, we show that it depends on the inbreeding coefficient F as well. Inbreeding increases the power to detect the role of a recessive or quasi-recessive disease-susceptibility factor. The gain in power turns out to be greater for small values of the gametic disequilibrium. Moreover, even in the absence of gametic disequilibrium, the presence of inbreeding may allow to detect the role of a recessive factor. Ignoring inbreeding when it exists may lead to reject falsely a recessive model if the mode of inheritance is inferred on the distribution of genotypes among patients. 5 refs., 6 figs., 1 tab.

  8. Fusion Power Associates annual meeting

    The Fusion Power Associates symposium, 'The Search for Attractive Fusion Concepts', was held January 31 - February 1 1985 in La Jolla, California. The purpose of this meeting was to bring together industry, university and government managers of the US fusion program to discuss the state of fusion development and the direction in which the program should be heading, given the cutbacks in the US fusion budget. There was a strong, minority opinion that until the best concept could be identified, the program should be broadly based. But there was also widespread criticism, aimed mainly at the largest segment of the magnetic fusion program, the tokamak. It was felt by many that the tokamak would not develop into a reactor that would be attractive to a utility and therefore should be phased out of the program. If the tokamak will indeed not lead to a commercial product then this meeting shows the US fusion program to be in a healthy state, despite the declining budgets

  9. Seven fatalities associated with ethylphenidate.

    Maskell, P D; Smith, P R; Cole, R; Hikin, L; Morley, S R


    Ethylphenidate is a stimulant novel psychoactive substance that is an analogue of the prescription drug methylphenidate (Ritalin(®)). Methylphenidate is used commonly for the treatment of attention deficit hyperactivity disorder. Due to its stimulant effects ethylphenidate is being abused. There is a single case report of a death associated with ethylphenidate in Germany, and a case series of 19 deaths in the East of Scotland, but otherwise, the contribution of ethylphenidate to death is poorly documented. We report the analytical results of 7 cases (between February 2013 and January 2015) in which ethylphenidate was detected and quantitated with a validated liquid chromatography tandem mass spectrometry method (LC-MS/MS). The individuals (all male) ranged in age from 23 to 49 years (median 25 years). The concentration of ethylphenidate in the cases ranged from 0.026mg/L to 2.18mg/L in unpreserved post-mortem femoral blood. Only one case had ethylphenidate present as a sole drug. All other cases had at least 2 other drug classes present (benzodiazepines, heroin, methadone antipsychotics, other new psychoactive compounds). Ethylphenidate toxicity was the sole contribution to the cause of death in one case. Hanging was the cause of death in 2 cases, with the other 4 cases being reported as having occurred due to mixed drug toxicity. These data will further help with the interpretation of post-mortem ethylphenidate levels. PMID:26829338

  10. Pantothenate kinase-associated neurodegeneration.

    Hartig, Monika B; Prokisch, Holger; Meitinger, Thomas; Klopstock, Thomas


    Pantothenate kinase-associated neurodegeneration (PKAN) is a hereditary progressive disorder and the most frequent form of neurodegeneration with brain iron accumulation (NBIA). PKAN patients present with a progressive movement disorder, dysarthria, cognitive impairment and retinitis pigmentosa. In magnetic resonance imaging, PKAN patients exhibit the pathognonomic "eye of the tiger" sign in the globus pallidus which corresponds to iron accumulation and gliosis as shown in neuropathological examinations. The discovery of the disease causing mutations in PANK2 has linked the disorder to coenzyme A (CoA) metabolism. PANK2 is the only one out of four PANK genes encoding an isoform which localizes to mitochondria. At least two other NBIA genes (PLA2G6, C19orf12) encode proteins that share with PANK2 a mitochondrial localization and all are suggested to play a role in lipid homeostasis. With no causal therapy available for PKAN until now, only symptomatic treatment is possible. A multi-centre retrospective study with bilateral pallidal deep brain stimulation in patients with NBIA revealed a significant improvement of dystonia. Recently, studies in the PANK Drosophila model "fumble" revealed improvement by the compound pantethine which is hypothesized to feed an alternate CoA biosynthesis pathway. In addition, pilot studies with the iron chelator deferiprone that crosses the blood brain barrier showed a good safety profile and some indication of efficacy. An adequately powered randomized clinical trial will start in 2012. This review summarizes clinical presentation, neuropathology and pathogenesis of PKAN. PMID:22515741

  11. Chemical evolution of OB associations

    Schramm, D. N.; Olive, K. A.


    It is determined that the existence of Al-26 and Pd-107 in meteorites in the early solar system indicates that our solar system probably formed inside an OB association that had been contaminated by the debris of at least one supernova. In addition to these radioactive tracers, the contamination of the material out of which the solar system formed would have significantly enriched the heavy element composition of the solar system relative to that of the average interstellar medium. It is found that the solar system would be enriched in those isotopes which are produced by the more massive stars, such as O-16, C-12, Ne-20, and some other r-process material. It is proposed that specific isotopic ratios and elemental ratios reflecting these differences would include the Ne-20/Ne-22 ratio, which would be higher in the solar system than in the interstellar medium and the cosmic rays, the C-12/C-13 ratio which would be higher in the solar system than in the interstellar medium, and the oxygen-to-carbon ratio, which would also be higher in the solar system than in the typical interstellar medium.

  12. Discoid Meniscus Associated With Achondroplasia.

    Hoernschemeyer, Daniel G; Atanda, Alfred; Dean-Davis, Ellen; Gupta, Sumit K


    Achondroplasia is the most common skeletal dysplasia. This form of dwarfism is caused by a point mutation in the fibroblast growth factor receptor 3 (FGFR3) gene, leading to inhibition of endochondral ossification for these patients. This results in a normal trunk height but shortened limbs. The discoid meniscus may be an important associated finding to better understand the common complaints of leg pain for these patients. Although the incidence for a discoid meniscus is between 3% and 5% for the general population, it is unknown with achondroplasia. This case series includes 4 patients, with ages ranging from adolescence to early adulthood, with symptoms of knee pain that were not attributable to some of the more common findings seen in this patient population. Typically, patients with achondroplasia who experience knee pain are evaluated for more common and well-known etiologies such as genu varum, ligamentous instability, and neurogenic claudication. However, the authors propose that symptomatic discoid lateral meniscus should be added to the differential diagnosis for lower-extremity pain in the achondroplasia population. A thorough history and physical examination, in combination with magnetic resonance imaging, can aid in making the diagnosis. Treatment with arthroscopic debridement, saucerization of the meniscus, and repair for unstable injuries has yielded good outcomes for this patient population. [Orthopedics. 2016; 39(3):e498-e503.]. PMID:27135452

  13. Nelarabine Associated Myotoxicity and Rhabdomyolysis

    Mahnur Haider


    Full Text Available Nelarabine (ara-G; Arranon; compound 506U78 is an antineoplastic purine analog used for the treatment of refractory or relapsed T-cell acute lymphoblastic leukemia (T-ALL and T-cell lymphoblastic lymphoma (T-LBL. The drug was granted accelerated approval in October 2005 by the US Food and Drug Administration (FDA given the efficacy (induction of complete responses noted in 2 single-arm trials (one in pediatric setting and one in adult patient population. The main spectra of toxicities that have been reported in these clinical trials and subsequent studies are hematological and neurological. Nelarabine induced rhabdomyolysis and increased creatinine phosphokinase (CK; CPK levels apparently have been reported and this side effect has been added as an adverse reaction in the product monograph from the drug company during postmarketing surveillance. However, the true extent and incidence of the myotoxicity from the drug are unclear. In this paper we report a grade IV CK elevation and rhabdomyolysis in a patient with T-ALL treated with nelarabine. Given the reported finding, we examined the literature further for myotoxicity, increased CK, and/or rhabdomyolysis associated with the use of the nelarabine and report our findings.

  14. Rethinking actions: implementation and association.

    Quandt, Lorna C; Chatterjee, Anjan


    Action processing allows us to move through and interact with the world, as well as understand the movements performed by other people. In recent years, there has been increasing interest in the semantics of actions as differentiated from the semantics of objects. However, as the understanding of action semantics has evolved, it is evident that the existing literature conflates two senses of the word 'action'-one that stems from studies of tool use and the other from event representation. In this paper, we suggest that this issue can be clarified by closely examining differences in how the human parietal and temporal cortices of the brain process action-related stimuli. By contrasting the posterior parietal cortex to the posterolateral temporal cortex, we characterize two complementary action systems in the human brain, each with its own specialization of function. We suggest that these two systems be referred to as the parietal Action Implementation System, and the posterolateral temporal Action Association System. While the frontoparietal system is concerned primarily with how we perform actions, and simulate others' actions, the temporal action system is more involved with processing actions from a third-person, conceptual standpoint. Recent work in cognitive neuroscience of perception and language, as well as the neuroanatomical organization of these brain regions support this distinction. We will discuss the implications of this work for cognition-, language-, and neuroscience-based action research. PMID:26352170

  15. Infections associated with body modification.

    Wong, Samson Sai-Yin; Wong, Sally Cheuk-Ying; Yuen, Kwok-Yung


    Although exact statistics are lacking, body modifications for cosmetic purposes are performed in many countries. The commonest forms include tattooing, body piercing, and breast and facial augmentation using implants or injectable fillers. Liposuction and, to a lesser extent, mesotherapy are also practiced in many countries. Infective complications of these procedures include local infections, transmission of bloodborne pathogens (viral hepatitis and human immunodeficiency virus), and distant infections such as infective endocarditis. Presence of foreign bodies, long healing time of piercing wounds, and poor compliance with infection control practices of some practitioners all predispose the recipients to infections. Apart from the endogenous microbial flora of the skin and mucosae, atypical mycobacteria, especially the rapid growers, have emerged as some of the most important pathogens in such settings. Outbreaks of infection are commonly reported. We hereby review the current knowledge of the topic with specific focus on infections associated with tattooing, body piercing, breast augmentation, mesotherapy, liposuction, and tissue filler injections. Greater awareness among consumers and health-care professionals, as well as more stringent regulations by the health authorities, is essential to minimize the health risks arising from these procedures. PMID:23265745

  16. Lithium-Associated Kidney Microcysts

    Jennifer Tuazon


    Full Text Available Long-term lithium therapy is associated with impairment in concentrating ability and, occasionally, progression to advanced chronic kidney disease from tubulointerstitial nephropathy. Biopsy findings in patients with lithium-induced chronic tubulointerstitial nephropathy include tubular atrophy and interstitial fibrosis interspersed with tubular cysts and dilatations. Recent studies have shown that cysts are seen in 33––62.5% of the patients undergoing lithium therapy. MR imaging is highly capable of defining renal morphological features and has been demonstrated to be superior to US and CT scan for the visualization of small renal cysts. The microcysts are found in both cortex and medulla, particularly in the regions with extensive atrophy and fibrosis, and can be multiple and bilateral. They tend to be sparse and do not normally exceed 1–2 mm in diameter. The renal microcysts in the image here reported are subtle, but consistent with lithium-induced chronic nephropathy. An MRI of the kidneys provides noninvasive evidence that strengthens the diagnosis of lithium-induced nephropathy.

  17. [Autoimmune Associated Encephalitis and Dementia].

    Watanabe, Osamu


    Antibodies against various neural surface antigens induce cognitive impairments. Anti-VGKC (voltage gated potassium channel) complex antibodies are well known as one of the causative autoantibodies. An anti-VGKC antibody was identified as the autoantibody in acquired neuromyotonia (Isaacs' syndrome), which causes muscle cramps and difficulty in opening the palm of the hands. However, this antibody also tests positive in autoimmune limbic encephalitis, which has a subacute progress and causes poor memory or epilepsy attacks. Typical cases have a distinctive adult-onset, frequent, brief dystonic seizure semiology that predominantly affects the arms and ipsilateral face. It has now been termed faciobrachial dystonic seizures. In recent years, the true target antigens of the anti-VGKC antibody of this VGKC limbic encephalitis have been recognized as leucine rich glioma inactivated protein (LGI)-1 and others. These antibodies to amnesia-related LGI-1 in limbic encephalitis neutralize the LGI-1-ADAM22 (an anchor protein) interaction and reduce synaptic AMPA receptors. There have been reports of limbic encephalitis associated with anti-VGKC complex antibodies mimicking Creutzfeldt-Jakob disease (CJD). Less than 2% of the patients with sporadic CJD (sCJD) develop serum anti-VGKC complex antibodies and, when positive, only at low titres. Low titres of these antibodies occur only rarely in suspected patients with sCJD, and when present, should be interpreted with caution. PMID:27056852

  18. Alagille Syndrome Associated with Xerophthalmia

    Elad Moisseiev


    Full Text Available Purpose: To report the occurrence of xerophthalmia and keratomalacia in a patient with Alagille syndrome. Methods: The patient's record and relevant literature were reviewed. Results: A 3-year-old boy with Alagille syndrome was examined at our institution due to severe bilateral ocular irritation. A corneal ulcer and keratomalacia were found in the right eye and severe dryness with corneal opacification was found in the left eye. He was treated with topical fortified antibiotics in the right eye, followed by amniotic membrane transplantation. Due to his systemic condition, characterized by severe cholestasis and intestinal malabsorption, a suspicion of vitamin A deficiency was raised and was later confirmed in serum analysis. Conclusion: This is the first report of xerophthalmia in a patient with Alagille syndrome. Vitamin A deficiency leading to xerophthalmia is common in developing countries; however, its occurrence in the West is rare, leading to a reduced awareness of this disorder amongst clinicians. Unusual eating habits, intestinal malabsorption and liver disease are possible causes for such a deficiency. The purpose of this case report is to raise awareness to the possibility of vitamin A deficiency in children with keratopathy, especially when associated with these disorders.

  19. Radiation problems associated with Skylab

    Braly, J. E.; Heaton, T. R.


    Radiation tests were conducted on the various types of Skylab film to establish the total radiation dosages compatible with an acceptable level of film fogging, and on the S190 borosilicate window to establish radiation limits for an acceptable darkening level. The results verified that most of the films would be unusable when returned to earth, and that the borosilicate window would be darkened beyond allowable limit, unless additional protection was provided. The operational solutions to these problems involve protecting the film with five film vaults and protecting the window with a radiation shield. The largest vault is made of aluminum and weighs over 2000 lb (its thickest compartment wall is 3.4 in.). The window radiation shield is a light honeycomb structure which is swung away for limited astronaut viewing or when the S190 experiment is in operation. Although the shield is light weight, it is heavy enough to stop the large number of low energy electrons making up a major part of the external environment and which are potentially damaging to the window. A brief description is given of the Skylab mission and some of the associated experiments. The radiation environment the spacecraft will encounter is discussed.

  20. Exploring branding associations in festival branding

    Dreyer, Adriana; Slabbert, Elmarie


    Arts festivals in South Africa are growing tremendously and it has become more important for these types of tourism products to position themselves competitively. Branding plays a major role in positioning and the associations made with the brand. It is necessary to understand these associations as well as factors influencing the associations. Therefore, the purpose of this research is to explore brand associations in festival branding and to determine the influence of demographic characteris...

  1. SNP Set Association Analysis for Familial Data

    Schifano, Elizabeth D.; Epstein, Michael P.; Bielak, Lawrence F.; Jhun, Min A; Kardia, Sharon L. R.; Peyser, Patricia A; Lin, Xihong


    Genome-wide association studies (GWAS) are a popular approach for identifying common genetic variants and epistatic effects associated with a disease phenotype. The traditional statistical analysis of such GWAS attempts to assess the association between each individual Single Nucleotide Polymorphism (SNP) and the observed phenotype. Recently, kernel machine-based tests for association between a SNP set (e.g., SNPs in a gene) and the disease phenotype have been proposed as a useful alternative...

  2. Association Between Diabetes Mellitus And Glaucoma

    Oshitari T


    It has not been determined definitively whether there is a significant association between diabetes mellitus (DM) and glaucoma. Some population-based studies have shown a positive association between diabetes and glaucoma, and others have shown negative association between diabetes and glaucoma. However in many studies that showed a lack of a significant association between diabetes and glaucoma, the diagnosis of DM was made by self-presentation.




    In this paper, a review of four different association rule mining algorithmsApriori, AprioriTid,Apriori hybrid and tertius algorithms and their drawbacks which would be helpful to find new solution for the Problems found in these algorithms and also presents a comparison between different association mining algorithms. Association rule mining is the one of the most important technique of the data mining. Its aim is to extract interesting correlations, frequent patterns and association among s...

  4. Efficient Mining of Intertransaction Association Rules

    Tung, A.K.H.; Lu, H.J.; Han, J.W.; Feng, L.


    Most of the previous studies on mining association rules are on mining intratransaction associations, i.e., the associations among items within the same transaction where the notion of the transaction could be the items bought by the same customer, the events happened on the same day, etc. In this s

  5. Review of Pain Associated with Minimal Endometriosis

    Demco, Larry


    Endometriosis has been examined in numerous ways and, primarily, it presents in two forms: painful, often associated with minimal findings; and non-painful, often associated with marked disease. The focus of this review article is to examine the pain aspect associated with minimal endometriosis.

  6. Action Tremor Associated with Lamotrigine Monotherapy

    Ji-Hye Yang


    Full Text Available Lamotrigine (LTG is associated with a tremor when given in combination with valproic acid; however, a tremor associated with lamotrigine monotherapy is rare. Here, we report a case of positional and action tremor associated with lamotrigine use. Based on the temporal relationship, it is conceivable that lamotrigine increases serotonin transmission or affects basal ganglia dopamine activity, thereby causing the tremor.

  7. Adrenomyeloneuropathy associated with congenital cataract

    Two cases of adrenomyeloneuropathy (AMN) in a family and the results of their MRI study are reported. Case 1, a 24-year-old male proband, was admitted to our hospital because of gait disturbance for three years. Bilateral cataracts were pointed out at birth, which required left side lenticotomy at age four. Neurological examinations on admission revealed a marked spastic paraparesis with pathological reflexes and a mild hypesthesia in the distal part of the left leg. No abnormal findings were detected in X-ray studies on the spine and spinal cord, electromyography and nerve conduction test. Serum very long chain fatty acids (VLCFAs) levels were apparently elevated, and the serum cortisol response to ACTH was low. Case 2, a 53-year-old woman, is the mother of Case 1 having a complaint of gait disturbance since age 51. She presented a mild spastic paraparesis with localized hypesthesia in the distal part of the both legs. She also had bilateral congenital cataracts. Her serum VLCFAs analysis indicated the intermediate levels between that of AMN and the normal control. Adrenal functions were normal. Cranial MRI (TR 2,000 msec/TE 80 msec) study disclosed high signal intensity areas in bilateral internal capsules in Case 1. These findings, suggesting the pathological change of dysmyelination, seemed to be well compatible with the clinical pictures. With these clinical findings and the laboratory data, these two cases were diagnosed as AMN. In addition, association of congenital cataract with AMN in both cases was characteristic in this family, which hasn't been reported in the literature. On regarding the genetic background of these two disorders, AMN and congenital cataract, it was speculated that each gene could be closely located on the same or very adjacent locus, possibly on Xq. (author)

  8. Analyze of Ventilator Associated Pneumonia

    Aysel Sunnetcioglu


    Full Text Available Aim: Ventilator-associated pneumonia (VAP is the infection that is an important cause of morbidity and mortality developed in patients whom the invasive mechanical ventilation (MV were performed in intensive care units (ICU. In this study, the factors of VAP developing in patients whom the mechanical ventilation of ICU performed, antibiotic susceptibility to these factors and determining the risk factors were aimed. Material and Method: Between January 2009 and March 2013, 79 cases, followed with the mechanical ventilation for at least for 48 hours and developed VAP, were retrospectively reviewed at Anesthesiology and Intensive Care Unit of Reanimation at Faculty of Medicine at Yuzuncu Yil University, performing endotracheal intubation. The cases were evaluated in terms of microorganisms, antibiotic susceptibility and risk factors. Results: The rate of our VAP speed was calculated to be 19.68 on the day of 1000 ventilator. While a single microorganism could be isolated in 81.1% of the 74 VAP cases whose the active pathogen could be isolated, two or more than two microorganisms were isolated in 18.9% of them.While 83 of the strains (90.2% were gram-negative bacteria, 7 of them (7.6% were gram-positive bacteria. Acinetobacter spp. (40.2% was most commonly isolated as a gram-negative factor, but methicillin-resistant S. aureus (4.3% was isolated as a gram-positive factor. It was determined that the isolated factors in VAP cases were significantly resistant to the broad-spectrum antibiotics. Discussion: As a result, in patients with high-risk factors for the development of VAP, early and appropriate empirical antibiotic treatment should be started according to the results of the sensitivity of the unit and for the multi-drug-resistant microorganisms with common and high mortality.

  9. Idiosyncratic Pancreatitis Associated with Perindopril

    Giuseppe Famularo


    Full Text Available The use of angiotensin-converting enzyme (ACE inhibitors is not associated with an increased risk of acute pancreatitis [1] and, so far, only one case has been linked with the use of perindopril [2]. We report on a second patient with perindopril-induced pancreatitis. A 72-year-old man presented with a 10-day history of nausea, vomiting, and constant pain in the epigastrium which radiated to the sides. Four weeks before admission, perindopril (4 mg/day had been added to the usual regimen of glyburide (5 mg/day, metformin (1 g/day and carvedilol (6.25 mg/day which the patient had been taking for three years for the treatment of diabetes mellitus and moderate hypertension. His previous history was otherwise unremarkable, except for psoriasis; he did not report any acute or chronic pancreatic disease and denied alcohol use, toxic habits or taking any other medications including over-the-counter medications or herbal remedies. Upon admission, the patient was fully alert and oriented, apyrexial and had normal vital parameters; physical examination yielded normal findings apart from a severely tender abdomen with no bowel sounds. Laboratory data showed increased blood amylase (556 IU/L; reference range: 0-115 IU/L and lipase (1,396 IU/L; reference range: 0-190 IU/L levels; electrolytes, hematological variables, cholesterol, triglycerides, liver and renal function tests, and blood gases were normal. The results of serologic tests for the Mycoplasma and Chlamydia species, viral hepatitis, and a wide range of other viral infections were also negative. Abdominal ultrasonography and computed tomography showed a moderately enlarged and edematous pancreas; furthermore, at imaging techniques no alterations such as stones or sludge of the gallbladder and of the common bile duct were detected. A chest X-ray was also normal.


    Kasthuri S


    Full Text Available Data mining is the process of identifying patterns from large amount of data. Association rule mining aims to discover dependency relationships across attributes. It may also disclose sensitive information. With extensive application of data mining techniques to various domains, privacy preservation becomes mandatory. Association rule hiding is one of the techniques of privacy preserving data mining to protect the sensitive association rules generated by association rule mining. This paper adopts heuristic approach for hiding sensitive association rules. The proposed technique makes the representative rules and hides the sensitive rules.

  11. Associative learning for a robot intelligence

    Andreae, John H


    The explanation of brain functioning in terms of the association of ideas has been popular since the 17th century. Recently, however, the process of association has been dismissed as computationally inadequate by prominent cognitive scientists. In this book, a sharper definition of the term "association" is used to revive the process by showing that associative learning can indeed be computationally powerful. Within an appropriate organization, associative learning can be embodied in a robot to realize a human-like intelligence, which sets its own goals, exhibits unique unformalizable behaviou

  12. Association Rules in the Relational Calculus

    Schulte, Oliver; Ester, Martin; Lu, Zhiyong


    One of the most utilized data mining tasks is the search for association rules. Association rules represent significant relationships between items in transactions. We extend the concept of association rule to represent a much broader class of associations, which we refer to as \\emph{entity-relationship rules.} Semantically, entity-relationship rules express associations between properties of related objects. Syntactically, these rules are based on a broad subclass of safe domain relational calculus queries. We propose a new definition of support and confidence for entity-relationship rules and for the frequency of entity-relationship queries. We prove that the definition of frequency satisfies standard probability axioms and the Apriori property.

  13. 75 FR 73076 - National Gas Supply Association, American Forest and Paper Association, Inc., American Public Gas...


    ...., American Public Gas Association, Independent Petroleum Association of America, Process Gas Consumers Group... Petroleum Association of America, and Process Gas Consumers Group (collectively, the Associations), filed in... desiring to intervene or to protest in this proceeding must file in accordance with Rules 211 and 214...

  14. Mesh Association by Projection along Smoothed-Normal-Vector Fields: Association of Closed Manifolds

    van Brummelen, E.H.


    The necessity to associate two geometrically distinct meshes arises in many engineering applications. Current mesh-association algorithms are generally unsuitable for the high-order geometry representations associated with high-order finite-element discretizations. In the present work we therefore propose a mesh-association method for high-order geometry representations. The associative map defines the image of a point on a mesh as its projection along a so-called smoothed normal-vector field...

  15. Helicobacter heilmannii-associated Gastritis: Clinicopathologic Findings and Comparison with Helicobacter pylori-associated Gastritis

    Joo, Mee; Kwak, Ji Eun; Chang, Sun Hee; Kim, Hanseong; Chi, Je G.; Kim, Kyung-Ah; Yang, Jeon Ho; Lee, June Sung; Moon, Young-Soo; Kim, Kyoung-Mee


    The aims of this study were to evaluate the clinicopathologic features of Helicobacter heilmannii-associated gastritis and to compare H. heilmannii-associated gastritis with H. pylori-associated gastritis. We reviewed 5,985 consecutive gastric biopsy specimens. All cases of chronic gastritis with Helicobacter infection were evaluated with the Updated Sydney System, and the grades of all gastritis variables were compared between H. heilmannii-associated gastritis and H. pylori-associated gastr...

  16. Association between γ-glutamyltransferase and prehypertension

    Qin, Xuzhen; Tang, Guodong; Qiu, Ling; XU, TAO; Cheng, Xinqi; Han, Shaomei; Zhu, Guangjin; Liu, Yajun


    Researchers have identified an association between baseline γ-glutamyltransferase (GGT) and prehypertension. However, data from China are limited. A cross-sectional study was performed among 2,205 subjects from Heilongjiang Province in China. Multiple logistic regression analyses revealed a significant association between baseline GGT and prehypertension [1.59, 95% confidence interval (CI), 1.18–2.16], comparing quartile 4 to quartile 1. Subgroup analyses showed a stronger association between...

  17. Severe Aplastic Anemia Associated With Eosinophilic Fasciitis

    de Masson, Adèle; Bouaziz, Jean-David; de Latour, Régis Peffault; Benhamou, Ygal; Moluçon-Chabrot, Cécile; Bay, Jacques-Olivier; Laquerrière, Annie; Picquenot, Jean-Michel; Michonneau, David; Leguy-Seguin, Vanessa; Rybojad, Michel; Bonnotte, Bernard; Jardin, Fabrice; Lévesque, Hervé; Bagot, Martine


    Abstract Diffuse eosinophilic fasciitis (Shulman disease) is a rare sclerodermiform syndrome that, in most cases, resolves spontaneously or after corticosteroid therapy. It has been associated with hematologic disorders, such as aplastic anemia. The clinical features and long-term outcomes of patients with eosinophilic fasciitis and associated aplastic anemia have been poorly described. We report the cases of 4 patients with eosinophilic fasciitis and associated severe aplastic anemia. For 3 ...

  18. Measuring degree-degree association in networks

    Raschke, Mathias; Schläpfer, Markus; Nibali, Roberto


    The Pearson correlation coefficient is commonly used for quantifying the global level of degree-degree association in complex networks. Here, we use a probabilistic representation of the underlying network structure for assessing the applicability of different association measures to heavy-tailed degree distributions. Theoretical arguments together with our numerical study indicate that Pearson's coefficient often depends on the size of networks with equal association structure, impeding a sy...

  19. Reliability analysis of an associated system

    陈长杰; 魏一鸣; 蔡嗣经


    Based on engineering reliability of large complex system and distinct characteristic of soft system, some new conception and theory on the medium elements and the associated system are created. At the same time, the reliability logic model of associated system is provided. In this paper, through the field investigation of the trial operation, the engineering reliability of the paste fill system in No.2 mine of Jinchuan Non-ferrous Metallic Corporation is analyzed by using the theory of associated system.


    Venkateswari S,


    Full Text Available Association Rule mining is one of the most popular data mining techniques which can be defined as extracting the interesting correlation and relation among large volume of transactions. E-commerce applications generate huge amount of operational and behavioral data. Applying association rule mining in e-commerce application can unearth the hidden knowledge from these data. In this paper a survey of association rule mining and its various applications in e-commerce environment are made.

  1. Mining association rules using formal concept analysis

    Pasquier, Nicolas


    In this paper, we give an overview of the use of Formal Concept Analysis in the framework of association rule extraction. Using frequent closed itemsets and their generators, that are defined using the Galois closure operator, we address two major problems: response times of association rule extraction and the relevance and usefulness of discovered association rules. We quickly review the Close and the A-Close algorithms for extracting frequent closed itemsets using their generators that redu...

  2. Improved Apriori Algorithm for Mining Association Rules

    Darshan M. Tank


    Association rules are the main technique for data mining. Apriori algorithm is a classical algorithm of association rule mining. Lots of algorithms for mining association rules and their mutations are proposed on basis of Apriori algorithm, but traditional algorithms are not efficient. For the two bottlenecks of frequent itemsets mining: the large multitude of candidate 2- itemsets, the poor efficiency of counting their support. Proposed algorithm reduces one redundant pruning operations of C...

  3. An Improved Technique for Ranking Semantic Associations

    S Narayana


    Full Text Available The primary focus of the search techniques in the first generation of the Web is accessing relevant documents from the Web. Though it satisfies user requirements, but it is insufficient as the user sometimes wishes to access actionable information involving complex relationships between two given entities. Finding such complex relationships (also known as semantic associations is especially useful in applications such as National Security, Pharmacy, Business Intelligence etc. Therefore the next frontier is discovering relevant semantic associations between two entities present in large semantic metadata repositories. Given two entities, there exist a huge number of semantic associations between two entities. Hence ranking of these associations is required in order to find more relevant associations. For this Aleman Meza et al. proposed a method involving six metrics viz. context, subsumption, rarity, popularity, association length and trust. To compute the overall rank of the associations this method computes context, subsumption, rarity and popularity values for each component of the association and for all the associations. However it is obvious that, many components appears repeatedly in many associations therefore it is not necessary to compute context, subsumption, rarity, popularity, and trust values of the components every time for each association rather the previously computed values may be used while computing the overall rank of the associations. This paper proposes a method to reuse the previously computed values using a hash data structure thus reduce the execution time. To demonstrate the effectiveness of the proposed method, experiments were conducted on SWETO ontology. Results show that the proposed method is more efficient than the other existing methods.

  4. Thyroid Associated Ophthalmopathy – A Review

    Mallika, PS; Tan, AK; Aziz, S.; Alwi, SAR Syed; Chong, MS; Vanitha, R.; Intan, G


    Thyroid associated ophthalmopathy is an autoimmune disorder affecting the orbital and periorbital tissues. Hyperthyroidism is commonly associated with thyroid associated ophthalmopathy, however in 5% to 10% of cases it is euthyroid. Genetic, environmental and endogenous factors play a role in the initiation of the thyroid ophthalmopathy. Smoking has been identified as the strongest risk factor for the development of the disorder. The pathogenesis involves activation of both humoral and cell m...

  5. Colourful Language: Measuring Word-Colour Associations

    Mohammad, Saif


    Since many real-world concepts are associated with colour, for example danger with red, linguistic information is often complimented with the use of appropriate colours in information visualization and product marketing. Yet, there is no comprehensive resource that captures concept-colour associations. We present a method to create a large word-colour association lexicon by crowdsourcing. We focus especially on abstract concepts and emotions to show that even though they cannot be physically ...

  6. An adaptive association test for microbiome data

    Wu, Chong; Chen, Jun; Kim, Junghi; Pan, Wei


    There is increasing interest in investigating how the compositions of microbial communities are associated with human health and disease. Although existing methods have identified many associations, a proper choice of a phylogenetic distance is critical for the power of these methods. To assess an overall association between the composition of a microbial community and an outcome of interest, we present a novel multivariate testing method called aMiSPU, that is joint and highly adaptive over ...

  7. Multi-Valued Associative Memory Neural Network

    修春波; 刘向东; 张宇河


    A novel learning method for multi-valued associative memory network is introduced, which is based on Hebb rule, but utilizes more information. According to the current probe vector, the connection weights matrix could be chosen dynamically. Double-valued and multi-valued associative memory are all realized in our simulation experiment. The experimental results show that the method could enhance the associative success rate.

  8. Association and Centrality in Criminal Networks

    Petersen, Rasmus Rosenqvist

    analyze the structural richness required to model and investigate criminal network entities and their associations. We demonstrate a need to rethink entity associations with one specific case (inspired by \\textit{The Wire}, a tv series about organized crime in Baltimore, United States) and corroborated by...... three of these associations and extend and test two centrality measures using CrimeFighter Investigator, a novel tool for criminal network investigation. Our findings show that the extended centrality measures offer new insights into criminal networks....

  9. How Associative Material Characteristics Create Textile Reflection

    Hasling, Karen Marie; Bang, Anne Louise


    materials and to reflect on, how personal associations can be embodied in [textile] materials. The discussion and results of the study stressed the coherence and differences of textile techniques used to express the given keywords and how the assignment has influenced the students’ material practice. How...... Associative Material Characteristics Create Textile Reflection (PDF Download Available). Available from: [accessed Dec 21, 2015]....

  10. American Speech-Language-Hearing Association

    ... Careers Certification Publications Events Advocacy Continuing Education Practice Management Research American Speech-Language-Hearing Association (ASHA) Making effective communication, a human ...

  11. Association Rule Mining and Its Application


    Several algorithms in data mining technique have been studied recently, among which association is one of the most important techniques. In this paper, we introduce theory of association rule in data mining, and analyze the characteristics of postal EMS service. We create a data warehouse model for EMS services and give the procedure of applying association rule mining based on it. In the end, we give an example of the whole mining procedure. This EMS-Data warehouse model and association rule mining technique have been applied in a practical Postal CRM System.

  12. A Unifying Probabilistic View of Associative Learning.

    Gershman, Samuel J


    Two important ideas about associative learning have emerged in recent decades: (1) Animals are Bayesian learners, tracking their uncertainty about associations; and (2) animals acquire long-term reward predictions through reinforcement learning. Both of these ideas are normative, in the sense that they are derived from rational design principles. They are also descriptive, capturing a wide range of empirical phenomena that troubled earlier theories. This article describes a unifying framework encompassing Bayesian and reinforcement learning theories of associative learning. Each perspective captures a different aspect of associative learning, and their synthesis offers insight into phenomena that neither perspective can explain on its own. PMID:26535896

  13. Chronic inflammatory demyelinating polyneuropathy associated with carcinoma.

    Antoine, J C; Mosnier, J. F.; Lapras, J; Convers, P.; Absi, L; Laurent, B.; Michel, D


    The association of chronic inflammatory demyelinating polyneuropathy (CIDP) and carcinoma has rarely been reported and its relevance is debated. Thirty three consecutive patients with probable or definite CIDP (idiopathic or associated with M protein) were investigated. Three patients with definite CIDP had a concomitant carcinoma. One had an IgM paraprotein. Steroids and intravenous immunoglobulins were effective.

  14. Lactation associated with herpes zoster pectoralis.

    Bhattacharya, S K; Girgla, H S


    The phenomenon of lactation associated with herpes zoster is unexpected. To our knowledge such an association has been reported only once. A case is reported in whom spontaneous lactation occurred in the ipsilateral breast following herpes zoster. It is believed to have resulted from stimulation of the intercostal nerve endings supplying the overlying skin of the breast. PMID:945354

  15. Complex radiation diagnosis of associated intracardiac abnormality

    It is shown that patients with congenital heart diseases having signs of cardiodismorphic complex in form of associated intercardiac abnormalities require special attention after surgical correction of the principal defect. It is connected with the fact that the associated abnormalities may become with time the basic factors influencing the progress and forecast of the disease

  16. Demographic and Lifestyle Variables Associated with Obesity

    Worthy, Sheri L.; Lokken, Kristine; Pilcher, Kenneth; Boeka, Abbe


    Objective: Overweight and obesity rates are associated with chronic diseases and higher rates of disability and continue to rise in the United States and worldwide. The purpose of this study was to build on past research and further investigate demographic and lifestyle variables associated with increased body mass index (BMI: kg/m[squared]).…

  17. Cross-cultural color-odor associations

    Levitan, C.A.; Ren, J.; Boesveldt, S.; Chan, J.; McKenzie, K.J.; Levin, J.A.; Leong, C.X.; Bosch, van den J.F.


    Colors and odors are associated; for instance, people typically match the smell of strawberries to the color pink or red. These associations are forms of crossmodal correspondences. Recently, there has been discussion about the extent to which these correspondences arise for structural reasons (i.e.

  18. Neutron Star/Supernova Remnant Associations

    Kaspi, V. M.


    The evidence for associations between neutron stars and supernova remnants is reviewed. After summarizing the situation for young radio pulsars, I consider the evidence from associations that young neutron stars can have properties very different from those of radio pulsars. This, though still controversial, shakes our simple perception of the Crab pulsar as prototypical of the young neutron star population.

  19. Adverse Reproductive Outcomes Associated With Teenage Pregnancy

    Yadav, Siddhartha; Choudhary, Dilip; Narayan, K.C.; Mandal, Rajesh Kumar; Sharma, Achyut; Chauhan, Siddharth Singh; Agrawal, Pawan


    Introduction It is debated whether teenage pregnancy is associated with an adverse reproductive outcome. This study assessed the reproductive outcomes in teenage pregnancy in Nepal, a developing setting. Methods A hospital based retrospective cohort study of 4,101 deliveries to compare the outcomes between teenage and non-teenage pregnancies. Results Pregnancy in teenagers was associated with significantly increased risk (P

  20. Theory of chain association versus liquid condensation

    Roij, R. van


    We combine the original van der Waals description for liquid condensation with the association theory of ideal particles into a simple association theory of nonideal chains. The theory shows that vapor-liquid coexistence becomes metastable if the tendency to form weakly interacting chains is suffici

  1. Genetic association studies in lumbar disc degeneration

    Eskola, Pasi J; Lemmelä, Susanna; Kjær, Per;


    Low back pain is associated with lumbar disc degeneration, which is mainly due to genetic predisposition. The objective of this study was to perform a systematic review to evaluate genetic association studies in lumbar disc degeneration as defined on magnetic resonance imaging (MRI) in humans....

  2. Monoclonal gammopathy associated with visceral leishmaniasis

    Vishal Sharma


    Full Text Available Monoclonal gammopathy can accompany diverse conditions and is usually benign. It should be distinguished from monoclonal gammopathy of undetermined significance (MGUS which can rarely turn malignant. Visceral leishmaniasis has only rarely been associated with monoclonal gammopathy. We describe the case of a 55-year-old male who had monoclonal gammopathy associated with visceral leishmanisais, which reversed with stibogluconate therapy.

  3. Catheter-Associated Urinary Tract Infections

    ... Top of page What is a urinary tract infection? A urinary tract infection (UTI) is an infection that involves ... page What is a catheter-associated urinary tract infection (CAUTI)? A catheter-associated urinary tract infection (CAUTI) occurs when germs (usually bacteria) ...

  4. Salmonella Typhimurium Outbreak Associated with Veterinary Clinic

    Cherry, Bryan; Burns, Amy; Johnson, Geraldine S.; Pfeiffer, Heidi; Dumas, Nellie; Barrett, Donna; McDonough, Patrick L.; Eidson, Millicent


    A Salmonella enterica serovar Typhimurium outbreak was associated with a veterinary clinic. Confirmed cases were in one cat, two veterinary technicians, four persons associated with clinic patients, and a nurse not linked to the clinic. This outbreak emphasizes the importance of strong public health ties to the animal health community.

  5. Implicit Measures of Association in Psychopathology Research

    Roefs, Anne; Huijding, Jorg; Smulders, Fren T. Y.; MacLeod, Colin M.; de Jong, Peter J.; Wiers, Reinout W.; Jansen, Anita T. M.


    Studies obtaining implicit measures of associations in Diagnostic and Statistical Manual of Mental Disorders (4th ed., Text Revision; American Psychiatric Association, 2000) Axis 1 psychopathology are organized into three categories: (a) studies comparing groups having a disorder with controls, (b)

  6. Implicit measures of association in psychopathology research

    A. Roefs; J. Huijding; F.T.Y. Smulders; C.M. MacLeod; P.J. de Jong; R.W. Wiers; A.T.M. Jansen


    Studies obtaining implicit measures of associations in Diagnostic and Statistical Manual of Mental Disorders (4th ed., Text Revision; American Psychiatric Association, 2000) Axis I psychopathology are organized into three categories: (a) studies comparing groups having a disorder with controls, (b)

  7. Hierarchical document categorization using associative networks

    Bloom, Niels; Theune, Mariët; Jong, de Franciska; Klement, E.P.; Borutzky, W.; Fahringer, T.; Hamza, M.H.; Uskov, V.


    Associative networks are a connectionist language model with the ability to handle dynamic data. We used two associative networks to categorize random sets of related Wikipedia articles with only their raw text as input. We then compared the resulting categorization to a gold standard: the manual ca

  8. Gallstones are associated with hidradenitis suppurativa

    Miller, Iben M; Vindsand Naver, Astrid; Mogensen, Ulla B;


    significant evidence was found with regard to hepatic dysfunction. CONCLUSION: This study demonstrates an association of HS with gallstones, but not with hepatic dysfunction. The association with gallstones may be partly explained by the comorbidity of hypertriglyceridemia and obesity as a part of MetS....

  9. Staff Association Handbook, 1974-75.

    Montgomery Coll. Staff Association, Takoma Park, MD.

    This handbook provides a list of Staff Senate and Committee members of the Staff Association of Montgomery College, a copy of the bylaws of the association, and sections of the college's "Policies and Procedures Manual" that affect staff employees. These sections of the manual pertain to: Administrative and Staff Communication; Affirmative Action…

  10. 12 CFR 615.5142 - Association investments.


    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Association investments. 615.5142 Section 615.5142 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM FUNDING AND FISCAL AFFAIRS, LOAN POLICIES AND OPERATIONS, AND FUNDING OPERATIONS Investment Management § 615.5142 Association...