WorldWideScience

Sample records for ascariasis

  1. Ascariasis

    ... enabling JavaScript. Top Banner Content Area Skip Content Marketing Share this: Main Content Area Ascariasis Ascariasis, or ... intestinal wall, the eggs reach your lungs by means of the bloodstream or lymphatic system. In your lungs, ...

  2. Biliary ascariasis

    Biliary ascariasis is a complication of intestinal ascariasis. This results in characteristic findings in the intravenous cholangiocholecystogram and in the sonogram. Characteristic signs of biliary ascariasis are, in the longitudinal section, the 'strip sign', 'spaghetti sign', 'inner tube sign', and in transverse section 'a bull's eye in the triple O'. The helminth can travel from out of the biliary duct system back into the intestinum, so that control examinations can even be negative. (orig.)

  3. Biliary ascariasis

    Mensing, M.; Cruz y Rivero, M.A.; Alarcon Hernandez, C.; Garcia Himmelstine, L.; Vogel, H.

    1986-06-01

    Biliary ascariasis is a complication of intestinal ascariasis. This results in characteristic findings in the intravenous cholangiocholecystogram and in the sonogram. Characteristic signs of biliary ascariasis are, in the longitudinal section, the 'strip sign', 'spaghetti sign', 'inner tube sign', and in transverse section 'a bull's eye in the triple O'. The helminth can travel from out of the biliary duct system back into the intestinum, so that control examinations can even be negative.

  4. Biliary ascariasis

    Sivakumar K

    2007-01-01

    Full Text Available Ascaris lumbricoides, or the common roundworms, has a worldwide distribution but is mainly seen in Asian and Latin American countries. In humans the usual habitat is in the small intestine, mainly in the jejunum. But if the worm load is high, which may go up to a thousand worms, the worms tend to migrate away from the usual site of habitat. This brief paper aims at highlighting the condition of biliary ascariasis through the authors′ experience in managing three such cases over a period of 1 year. The clinical features which arouse suspicion of biliary ascariasis, as well as diagnostic modalities and management, are described. Initially the cases were managed conservatively, but we conclude that if worms are retained in biliary tree for more than 10 days, surgery should be performed; since retention of degraded and calcified dead worm can occur, and this can lead to complications which are difficult to manage.

  5. Biliary ascariasis

    Sivakumar K; Varkey Sam; George Mathan; Rajendran S; Hema R

    2007-01-01

    Ascaris lumbricoides, or the common roundworms, has a worldwide distribution but is mainly seen in Asian and Latin American countries. In humans the usual habitat is in the small intestine, mainly in the jejunum. But if the worm load is high, which may go up to a thousand worms, the worms tend to migrate away from the usual site of habitat. This brief paper aims at highlighting the condition of biliary ascariasis through the authors′ experience in managing three such cases over a perio...

  6. Gall bladder ascariasis

    Ranendra Hajong

    2013-01-01

    Full Text Available Hepatobiliary ascariasis is commonly reported from highly endemic regions like India, Bangladesh, Latin America, parts of Middle East and Africa. In humans, the usual habitat of Ascaris lumbricoides is the small intestine. When the worm load is high, going as high as more than 1000 worms, then the worms tend to migrate away from the usual site. Patients with hepatobiliary ascariasis may present with biliary colic due to obstruction caused by the worms in the gall bladder, common bile duct or as a result of obstructive symptoms caused by calcified worms or lithiasis, which is commonly found in patients with hepatobiliary ascariasis. Acute pancreatitis may also be caused by ascariasis. Management usually is conservative if it is still alive or can be extracted by endoscopic retrograde cholangio-pancreatography or surgery.

  7. Hepatic and Biliary Ascariasis

    Anup K Das

    2014-01-01

    Ascariasis mainly contributes to the global helminthic burden by infesting a large number of children in the tropical countries. Hepato-biliary ascariasis (HBA) is becoming a common entity now than in the past owing to the frequent usage of ultrasonograms and endoscopic diagnostic procedures in the clinical practice. There are a variety of manifestations in HBA and diagnosis depends on a high index of suspicion in endemic areas coupled with subsequent confirmation by sonographic or endoscopic...

  8. Gall bladder ascariasis

    Ranendra Hajong

    2013-01-01

    Hepatobiliary ascariasis is commonly reported from highly endemic regions like India, Bangladesh, Latin America, parts of Middle East and Africa. In humans, the usual habitat of Ascaris lumbricoides is the small intestine. When the worm load is high, going as high as more than 1000 worms, then the worms tend to migrate away from the usual site. Patients with hepatobiliary ascariasis may present with biliary colic due to obstruction caused by the worms in the gall bladder, common bile duct or ...

  9. Appendiceal ascariasis in children

    2010-01-01

    BACKGROUND: The propensity of Ascaris lumbricoides to wander leads to varied surgical complications in the abdomen. Wandering A lumbricoides may sometimes reach the vermiform appendix and its presence there may remain silent or incite pathology. Our aim was to study ascariadial appendicitis. METHODS: Over a period of 3 years, we identified children who were found to have appendiceal ascariasis during surgery for different intestinal complications due to ascariasis. We studied the relationship...

  10. Pancreatic ascariasis with periampullary carcinoma

    Arulprakash, S; Sahu, Manoj Kumar; Dutta, Amit Kumar; Joseph, A; Chandy, George M.

    2015-01-01

    Ascarias lumbricoides infestation is endemic in tropical countries. Most infections are asymptomatic, but it can produce a wide spectrum of manifestations including hepatobiliary and pancreatic complications. There are reports of association of biliary ascariasis with bilary malignancies in the past, but same is not known for pancreatic ascariasis. We report a case of association of periampullary malignancy with pancreatic ascariasis.

  11. Albendazole Therapy in Ascariasis

    Ishtyak Ahmed Mir ,Nazir Ahmed Wani, Rekha Patnaik

    2003-01-01

    Patients in the paediatric age group with moderate to severe intestinal ascariasis were treated withvarious antihelminthic dJugs. Albendazole, Pyrantel pamoate and Levamisole were used. Comparisonofthe percentage cure rate, was made and albendazole was found to be the most effective in 92.26%of patients followed by pyrantel pamoate and levamisole in 80.82% and 64.70% of the patientsrespectively.

  12. Biliary ascariasis. A case report.

    Sarihan, H; Gürkök, S; Sari, A

    1995-01-01

    Ascaris lumbricoides is a worldwide intestinal infestation that may cause various complications. Biliary ascariasis, however, is a rare condition. We describe a child with biliary ascariasis. The patient's clinical symptoms were pain, vomiting and abdominal tenderness, and she was thought to have acute appendicitis. However, laboratory examination revealed high serum alkaline phosphatase and amylase levels, and ultrasonography and percutaneous cholangiography demonstrated biliary ascariasis. The patient was successfully treated with mebendazole and antispasmolytic drugs. PMID:8560608

  13. Imaging of ascariasis

    Full text: Ascaris lumbricoides is one of the most common parasitic infestations of the gastrointestinal tract worldwide. During the intestinal phase of the disease, the adult worms usually remain clinically silent, sometimes causing a variety of non-specific abdominal symptoms. When present in large numbers, the worms may get intertwined into a bolus, causing intestinal obstruction, volvulus or even perforation. Occasionally, the adult Ascaris worm may migrate into the Vater's ampulla and enter the bile duct, gall bladder or pancreatic duct, leading to a variety of complications such as biliary colic, gallstone formation, cholecystitis, pyogenic cholangitis, liver abscess and pancreatitis. Imaging plays a significant role in showing the presence of worms and possible complications in intestinal as well as hepatobiliary ascariasis. This pictorial essay aims to illustrate various imaging features of ascariasis and its associated complications

  14. Albendazole Therapy in Ascariasis

    Ishtyak Ahmed Mir ,Nazir Ahmed Wani, Rekha Patnaik

    2003-10-01

    Full Text Available Patients in the paediatric age group with moderate to severe intestinal ascariasis were treated withvarious antihelminthic dJugs. Albendazole, Pyrantel pamoate and Levamisole were used. Comparisonofthe percentage cure rate, was made and albendazole was found to be the most effective in 92.26%of patients followed by pyrantel pamoate and levamisole in 80.82% and 64.70% of the patientsrespectively.

  15. Hepatic and biliary ascariasis

    Anup K Das

    2014-01-01

    Full Text Available Ascariasis mainly contributes to the global helminthic burden by infesting a large number of children in the tropical countries. Hepato-biliary ascariasis (HBA is becoming a common entity now than in the past owing to the frequent usage of ultrasonograms and endoscopic diagnostic procedures in the clinical practice. There are a variety of manifestations in HBA and diagnosis depends on a high index of suspicion in endemic areas coupled with subsequent confirmation by sonographic or endoscopic demonstration of the worm. Most of them present with acute abdomen and jaundice. Oriental or recurrent pyogenic cholangiopathy is possibly the result of HBA, commonly encountered in South-East Asian countries. Conservative treatment with anthelminthic agents is used in the majority. Failure to respond to medical therapy usually indicates the need for endoscopic or surgical interventions. Overall, mortality is low and prognosis is good, but many epidemiological and immunological aspects of Ascaris infection are unclear, meaning our understanding the disease and infection still remains incomplete. Therefore, it is difficult to definitely put down a fixed modality of treatment for HBA. This underscores the need for further studies as ascariasis has the potential to adversely affect the national socio-economy by compromising the health of children and adults alike with its sheer number.

  16. Biliary ascariasis: radiological clue to diagnosis

    Sundriyal, Deepak; Bansal, Satish; KUMAR, NAVEEN; Sharma, Navneet

    2015-01-01

    Ascariasis is caused by Ascaris lumbricoides. It is the most common helminthic infection seen worldwide. Ascariasis is an endemic disease in our country. This is due to the prevailing poor sanitary conditions and low level of education. Biliary ascariasis is an uncommon cause of obstructive jaundice. We report a case of biliary ascariasis in a young labourer who presented with acute abdominal pain.

  17. Tilfaeldigt fund af biliaer ascariasis

    Kristensen, Anders Donatsky; Achiam, Michael

    2010-01-01

    We describe a case of biliary ascariasis in a 27-year-old Philippine au-pair with recurrent upper abdominal pain. Hepatobiliary ascariasis is rarely seen in non-endemic areas. The diagnosis is important because severe complications can occur. If migrated into the biliary tree, it is recommended to...

  18. Magnetic resonace appearance of Gall Bladder Ascariasis

    Arya Prafull

    2005-05-01

    Full Text Available Ascariasis is a common disease in many developing countries and is a common cause of biliary and pancreatic diseases in endemic areas. Numerous studies have been published on biliary tract ascariasis. All these have documented ultrasonography as the primary imaging modality for biliary tract ascariasis. Magnetic Resonance Cholangiopancreatography (MRCP has been the latest entrant for the study of bilary tract. MRCP findings of biliary tract ascariasis have been scarcely documented. MRCP is a unique non-invasive investigation for demonstrating ascariasis in Gall bladder and bilary tract clearly. We present MR appearances of Gall bladder and biliary tract in a proven case of biliary ascariasis.

  19. Ascariasis cholecystitis: An unusual cause

    Shetty Balakrishna

    2008-01-01

    Full Text Available Ascariasis is the most common helminthic infection to infest man. Usually the adult worm lives in the small intestine. Rarely it migrates through the ampulla of vater and enters the common bile duct. We are reporting a case of gall bladder ascariasis causing acute cholecystitis treated by laparoscopic cholecystectomy. Presence of Ascaris lumbricoides in gallbladder is rare entity as it is difficult to reach there due to the narrow and tortuous cystic duct.

  20. Ascariasis cholecystitis: An unusual cause

    Shetty Balakrishna; Shetty Prashanth; Sharma Pritam

    2008-01-01

    Ascariasis is the most common helminthic infection to infest man. Usually the adult worm lives in the small intestine. Rarely it migrates through the ampulla of vater and enters the common bile duct. We are reporting a case of gall bladder ascariasis causing acute cholecystitis treated by laparoscopic cholecystectomy. Presence of Ascaris lumbricoides in gallbladder is rare entity as it is difficult to reach there due to the narrow and tortuous cystic duct.

  1. Magnetic resonace appearance of Gall Bladder Ascariasis

    Arya Prafull; Kukreti Ranjan; Arya Muktanjali; Gupta Sachida

    2005-01-01

    Ascariasis is a common disease in many developing countries and is a common cause of biliary and pancreatic diseases in endemic areas. Numerous studies have been published on biliary tract ascariasis. All these have documented ultrasonography as the primary imaging modality for biliary tract ascariasis. Magnetic Resonance Cholangiopancreatography (MRCP) has been the latest entrant for the study of bilary tract. MRCP findings of biliary tract ascariasis have been scarcely documented. MRCP is a...

  2. Biliary ascariasis: radiological clue to diagnosis.

    Sundriyal, Deepak; Bansal, Satish; Kumar, Naveen; Sharma, Navneet

    2015-03-01

    Ascariasis is caused by Ascaris lumbricoides. It is the most common helminthic infection seen worldwide. Ascariasis is an endemic disease in our country. This is due to the prevailing poor sanitary conditions and low level of education. Biliary ascariasis is an uncommon cause of obstructive jaundice. We report a case of biliary ascariasis in a young labourer who presented with acute abdominal pain. PMID:26634136

  3. Ascariasis of the pancreatic duct.

    Klimovskij, Michail; Dulskas, Audrius; Kraulyte, Zita; Mikalauskas, Saulius

    2015-01-01

    Ascariasis is a common helminthic disease worldwide, although Lithuania and other European countries are not considered endemic areas. The presence of the Ascaris worm in the biliary tree causes choledocholithiasis-like symptoms. We report a case of pancreatic duct ascariasis causing such symptoms. A 73-year-old Lithuanian woman underwent endoscopic retrograde cholangiopancreatography (ERCP) suspecting choledocholithiasis. Contrast injection into the common bile duct demonstrated a slightly dilated biliary tree without any filling defects, and the tail of an Ascaris worm protruding from the opening of the papilla Vater. The worm was captured by a snare but escaped deep into the duct. After a small wirsungotomy the worm was retrieved from the pancreatic duct. The patient received a 150 mg dose of levamisole orally repeated 7 days later and was discharged after complete resolution of symptoms. This first reported sporadic case of pancreatic duct ascariasis in Lithuania was successfully treated with ERCP and Levamisole. PMID:26374772

  4. Laproscopic Management of Wandering Biliary Ascariasis

    Umesh Jethwani; G. J. Singh; Sarangi, P; Vipul Kandwal

    2012-01-01

    Ascariasis is one of the most common helminthic diseases in humans, occurring mostly in countries with low standards of public health and hygiene, thereby making ascariasis highly endemic in developing countries. In endemic areas, 30% of adults and 60–70% of children harbour the adult worm. Biliary ascariasis is a rare cause of obstructive jaundice. Conventional management involves endoscopic extraction of worm. We are reporting a rare case of ascaris which induced extrahepatic biliary obstru...

  5. HEPATOBILIARY ASCARIASIS: 2 CASE REPORT

    Samrendra Nath; Satya Prakash

    2016-01-01

    Hepatobiliary ascariasis is a relatively uncommon helminthic disease occasionally found in Indian subcontinent and third world country. They commonly present as right hypochondrial pain with mild jaundice. Vomiting may also be associated finding of this disease. Ultrasound investigation is an important, easily available, low cost tool for early diagnosis and followup. Its safety, accuracy, easy repeatability, quick and non-invasive property makes it the first and prime modality fo...

  6. Laproscopic Management of Wandering Biliary Ascariasis

    Umesh Jethwani

    2012-01-01

    Full Text Available Ascariasis is one of the most common helminthic diseases in humans, occurring mostly in countries with low standards of public health and hygiene, thereby making ascariasis highly endemic in developing countries. In endemic areas, 30% of adults and 60–70% of children harbour the adult worm. Biliary ascariasis is a rare cause of obstructive jaundice. Conventional management involves endoscopic extraction of worm. We are reporting a rare case of ascaris which induced extrahepatic biliary obstruction in a young male who presented with acute cholangitis. The ascaris was removed by laparoscopic exploration of the common bile duct. Postoperative period was uneventful.

  7. Our experience of biliary ascariasis in children

    Wani M; Chechak Bashir; Reshi Farooq; Pandita Sanjay; Rather Muddasar; Sheikh Tariq; Ganie Ishfaq

    2006-01-01

    Ascariasis is highly endemic in Kashmir valley as temperate climate and wet soil provide excellent conditions for its development. We studied 198 cases (11%) of biliary ascariasis out of 1,800 patients of worm infestation from December 2001 to December 2004 in the age group of 4-15 years. In our study, we found biliary ascariasis to be more common in female children, and most common clinical presentation was biliary colic in 143 patients, cholangitis in 28, cholecystitis in 15, liver a...

  8. Pulmonary ascariasis in tropical communities.

    Spillmann, R K

    1975-09-01

    To determine the incidence of Loeffler's syndrome in a tropical region, a survey was conducted over a 1-year period in two locations in Colombia, South America, one inland and urban (Cali), the other rural and coastal (Guapi). Among 700 hospitalized patients, 12,000 patients coming to health centers, and 44 families with 328 members, 4 cases of Loeffler's syndrome were found--3 during the survey and 1 before it began. Only one was typical and of some severity. None of the family members developed a perceptible reaction to larvae, though surveillance was close and 83 new intestinal infections were documented. Infection rates for intestinal ascariasis were 25% to 30% in Cali, and 80% to 90% in Guapi. When infections in 30 families were eliminated, previous levels of infection were reached within 10 months. When undisturbed by treatment, the levels of intestinal infection remained stable or showed fluctuations which were not linked to climatic changes. In view of the high prevalence of infection and year-round transmission, which was assumed to occur frequently in the population, it is noteworthy that symptomatic pulmonary ascariasis appeared to be rare and complications from adult worms in heavy infections were uncommon. The findings suggest that frequent and uninterrupted contact between Ascaris lumbricoides and its host results in a high degree of natural tolerance and control. PMID:1238026

  9. An Unusual Presentation of Biliary Ascariasis

    Arsad Bashir Khan, Sanjay Kumar Bhasin, Rajesh Kumar Bhagat, R. K. Chrungoo

    2007-01-01

    Ascariasis is one of the most common disease in human being worldwide. Ascariasis is 2nd to gall stone asa cause of biliary symptoms. The invasion of biliary tract by round worms during early post operativeperiod is an infrequent but serious complication. We present 42 years old man operated for cholelithiasiswith Choledocholthiasis on whom choledochotomy and T -Tube insertion was done. On 5th postoperativeday Ascaris extruded peri-T-Tube and immediate T - Tube cholangiogram done that showed ...

  10. A Case of Ascariasis Mimicking Jejunal Intussusception

    Sekmenli, Tamer; Ciftci, Ilhan; Emiroglu, Halil Haldun; Koplay, Mustafa

    2015-01-01

    Intussusception is the common abdominal emergency in early childhood. The clinical presentation is characterized by the triad of abdominal colics, red jelly stools (positive in 66%) and a palpable mass (70%). Ascariasis is a common infestation in tropical countries because of poor hygiene and low socioeconomic conditions. Ascariasis can cause serious intra-abdominal complications such as intestinal obstruction. We have reported a case of abdominal pain and intestinal obstruction, which was fi...

  11. Ultrasonographic features of pseudotumorous form of ascariasis

    We report the ultrasonographic findings of a 60 year old woman with pseudotumorous form of ascariasis. Real-time ultrasonographic examination using a curved array transducer revealed grossly thickened small bowel loops, multiple small circular deposits throughout the peritoneal cavity, and a moderate amount of ascites. The English literature on the different forms of abdominal ascariasis is reviewed. Specific signs, which include the 'strip' sign, the 'four-lines', 'inner tube', or 'double tube' sign, the 'bull's eye' or 'target' sign, a 'worm mass' or 'spaghetti-like' appearance, and the 'zig-zag' sign can be present in any form of abdominal ascariasis, as they represent the image of the Ascaris worms visualized under ultrasonographic examination. However, the non-specific signs are not peculiar to A. lumbricoides infections, but are results of secondary changes due to A. lumbricoides infections in the corresponding organs

  12. Incidence of ascariasis in gastric carcinoma

    Prompted by the finding that the radiological incidence of small bowel ascariasis in the patient with gastric carcinoma was unexpectedly lower than the incidence in the normal population, a clinical study was performed to investigate possible relationship between gastric carcinoma and intestinal ascariasis. As a preliminary survey, we reviewed the radiological incidence of ascariasis in a total of 2,446 cases of upper GI series performed at the Department of Radiology, St Mary's Hospital Catholic Medical College. These included 1,573 normal subjects, 146 gastric carcinoma patients, 100 benign gastric ulcer and 249 duodenal ulcer patients and 378 other upper GI diseases. Following the preliminary study, a more accurate parasitologic study was conducted in another 578 normal subjects and 51 gastric carcinoma patients. The radiological incidences of ascaiasis in normal subjects and gastric carcinoma patients were 15.1% and 28.1%, respectively. The incidence of overall helminthiasis including ascaris lumbricoides, trichocephalus trichiurus and trichostrongyloides orientalis in normal subjects of the present series was 73.5%. This figure is virtually the same with 69.1% of the general population incidence reported by Kim, et al. (1971), but the incidence in gastric carcinoma patients was 94.1%. The high incidence pattern of overall helminthiasis in gastric carcinoma patients is, however, reversed as for as ascariasis is concerned. Thus, the incidence of ascariasis of gastric carcinoma patients was much lower than that of normal subjects (9.8% vs 19.4%). From the present observation, it is postulated that there can be some possible antagonistic relationship between evolution of gastric carcinoma and small bowel infestation of ascaris lumbricoides

  13. Incidence of ascariasis in gastric carcinoma

    Kim, Jong Woo; Rhee, Hak Song; Bahk, Yong Whee [St Mary' s Hospital Catholic Medical College, Seoul (Korea, Republic of)

    1972-09-15

    Prompted by the finding that the radiological incidence of small bowel ascariasis in the patient with gastric carcinoma was unexpectedly lower than the incidence in the normal population, a clinical study was performed to investigate possible relationship between gastric carcinoma and intestinal ascariasis. As a preliminary survey, we reviewed the radiological incidence of ascariasis in a total of 2,446 cases of upper GI series performed at the Department of Radiology, St Mary's Hospital Catholic Medical College. These included 1,573 normal subjects, 146 gastric carcinoma patients, 100 benign gastric ulcer and 249 duodenal ulcer patients and 378 other upper GI diseases. Following the preliminary study, a more accurate parasitologic study was conducted in another 578 normal subjects and 51 gastric carcinoma patients. The radiological incidences of ascaiasis in normal subjects and gastric carcinoma patients were 15.1% and 28.1%, respectively. The incidence of overall helminthiasis including ascaris lumbricoides, trichocephalus trichiurus and trichostrongyloides orientalis in normal subjects of the present series was 73.5%. This figure is virtually the same with 69.1% of the general population incidence reported by Kim, et al. (1971), but the incidence in gastric carcinoma patients was 94.1%. The high incidence pattern of overall helminthiasis in gastric carcinoma patients is, however, reversed as for as ascariasis is concerned. Thus, the incidence of ascariasis of gastric carcinoma patients was much lower than that of normal subjects (9.8% vs 19.4%). From the present observation, it is postulated that there can be some possible antagonistic relationship between evolution of gastric carcinoma and small bowel infestation of ascaris lumbricoides.

  14. Biliary Ascariasis Mimicking Colonic Tumor Infiltration of the Biliary System.

    Sundriyal, Deepak; Mittal, Gyanendra; Kumar, Sushil; Manjunath, Suraj; Sharma, Navneet; Gupta, Mahesh

    2015-09-01

    Ascariasis is a common problem in developing countries with poor hygiene and sanitation. It is endemic in India and usually seen in the northern states. Biliary ascariasis is an uncommon cause of obstructive jaundice. We present a case of carcinoma of hepatic flexure of colon in which the patient developed biliary ascariasis and posed a diagnostic challenge as it mimicked tumor infiltration of the biliary system. PMID:27217679

  15. An Unusual Presentation of Biliary Ascariasis

    Arsad Bashir Khan, Sanjay Kumar Bhasin, Rajesh Kumar Bhagat, R. K. Chrungoo

    2007-01-01

    Full Text Available Ascariasis is one of the most common disease in human being worldwide. Ascariasis is 2nd to gall stone asa cause of biliary symptoms. The invasion of biliary tract by round worms during early post operativeperiod is an infrequent but serious complication. We present 42 years old man operated for cholelithiasiswith Choledocholthiasis on whom choledochotomy and T -Tube insertion was done. On 5th postoperativeday Ascaris extruded peri-T-Tube and immediate T - Tube cholangiogram done that showed multiplefilling defects in Common Bile Duct (CBD. Patient was managed with saline irrigation of CBD viaT-Tube and anti-heliminthic was given. In view of its rarity and unusual presentation the case is beingreported.

  16. Obstructive jaundice induced by biliary ascariasis

    Keating, Aine; Quigley, James Aidan; Genterola, Al Frederick

    2012-01-01

    Ascaris lumbricoides is one of the most prevalent parasitic infections, especially in developing countries. Its presence can lead to a multitude of presentations, one of the rarer ones being obstructive jaundice due to migration of the worm in to the biliary tree. We describe a case of a man who presented as an emergency to the general surgeons complaining of abdominal pain, fever, jaundice and vomiting. Ultrasound was used and the diagnosis of biliary ascariasis was made. The patient underwe...

  17. Biliary Ascariasis Coinciding Hepatitis a Infection

    Özen, Metehan; Güngör, Serdal; Karakurt, Cemşit; Kutlu, Ramazan

    2007-01-01

    Intestinal ascariasis is one of the most common parasitic infestation in developing countries. Fifteen years-old male was admitted with the complaints of jaundice, abdominal pain and nausea. Laboratory investigations revealed positivity of anti-HAV-IgM and IgG. We performed abdominal ultrasonography because of long-lasting jaundice and increasing abdominal crampy pain. Examination revealed 7-8 cm long tubular image which is consistent with Ascaris lumbricoides. Single dose albendazole and an...

  18. Our experience of biliary ascariasis in children

    Wani M

    2006-01-01

    Full Text Available Ascariasis is highly endemic in Kashmir valley as temperate climate and wet soil provide excellent conditions for its development. We studied 198 cases (11% of biliary ascariasis out of 1,800 patients of worm infestation from December 2001 to December 2004 in the age group of 4-15 years. In our study, we found biliary ascariasis to be more common in female children, and most common clinical presentation was biliary colic in 143 patients, cholangitis in 28, cholecystitis in 15, liver abscess 7, pancreatitis 4 and postoperative worm infestation in 1 patient. Ultrasonography of abdomen was the diagnostic tool of choice with hundred percent results. Most of the patients were managed conservatively. ERCP was not done in children because of need of general anesthesia and difficulty in performing the procedure. Surgical intervention was required in 23 patients (cholecystectomy with CBD exploration in 5, choledochotomy alone in 13, drainage of liver abscess in 3, choledochoduodenostomy in 1 and peritoneal lavage in 1.

  19. Ultrasonographic features of pseudotumorous form of ascariasis

    Hui, Joyce Y.H.; Woo, Patrick C.Y. E-mail: pcywoo@hkucc.hku.hk; Kan, Pan Shing; Lai, Yeong Man; Tang, Alice P.Y

    2001-09-01

    We report the ultrasonographic findings of a 60 year old woman with pseudotumorous form of ascariasis. Real-time ultrasonographic examination using a curved array transducer revealed grossly thickened small bowel loops, multiple small circular deposits throughout the peritoneal cavity, and a moderate amount of ascites. The English literature on the different forms of abdominal ascariasis is reviewed. Specific signs, which include the 'strip' sign, the 'four-lines', 'inner tube', or 'double tube' sign, the 'bull's eye' or 'target' sign, a 'worm mass' or 'spaghetti-like' appearance, and the 'zig-zag' sign can be present in any form of abdominal ascariasis, as they represent the image of the Ascaris worms visualized under ultrasonographic examination. However, the non-specific signs are not peculiar to A. lumbricoides infections, but are results of secondary changes due to A. lumbricoides infections in the corresponding organs.

  20. Radiological findings of intraparenchymal liver Ascaris (hepatobiliary ascariasis)

    Akata, D.; Oezmen, M.N.; Kaya, A.; Akhan, O. [Dept. of Radiology, Hacettepe University School of Medicine, Ankara (Turkey)

    1999-02-01

    Ascariasis is a well-known cause of acute cholangitis and cholecystitis; however, very rarely do worms penetrate and colonize the liver parenchyma. Here we present the unique radiological demonstration (US, CT and ERCP) of hepatobiliary ascariasis in which worm was first alive in the parenchyma of the liver and subsequently died and formed liver abscess. (orig.) (orig.) With 3 figs., 8 refs.

  1. Biliary ascariasis: MR cholangiography findings in two cases

    Hwang, Cheol Mok; Kim, Tae Kyoung; Ha, Hyun Kwon; Kim, Pyo Nyun; Lee, Moon Gyu [Ulsan University College of Medicine, Seoul (Korea, Republic of)

    2001-09-01

    We describe the imaging features of two cases of biliary ascariasis. Ultrasonography and CT showed no specific abnormal findings, but MR cholangiography clearly demonstrated an intraductal linear filling defect that led to the correct diagnosis. MR cholangiography is thus a useful technique for the diagnosis of biliary ascariasis.

  2. Radiological findings of intraparenchymal liver Ascaris (hepatobiliary ascariasis)

    Ascariasis is a well-known cause of acute cholangitis and cholecystitis; however, very rarely do worms penetrate and colonize the liver parenchyma. Here we present the unique radiological demonstration (US, CT and ERCP) of hepatobiliary ascariasis in which worm was first alive in the parenchyma of the liver and subsequently died and formed liver abscess. (orig.) (orig.)

  3. Biliary Ascariasis: MR Cholangiography Findings in Two Cases

    Hwang, Cheol Mok; Kim, Tae Kyoung; Ha, Hyun Kwon; Kim, Pyo Nyun; Lee, Moon-Gyu

    2001-01-01

    We describe the imaging features of two cases of biliary ascariasis. Ultrasonography and CT showed no specific abnormal findings, but MR cholangiography clearly demonstrated an intraductal linear filling defect that led to the correct diagnosis. MR cholangiography is thus a useful technique for the diagnosis of biliary ascariasis.

  4. Biliary ascariasis: MR cholangiography findings in two cases

    We describe the imaging features of two cases of biliary ascariasis. Ultrasonography and CT showed no specific abnormal findings, but MR cholangiography clearly demonstrated an intraductal linear filling defect that led to the correct diagnosis. MR cholangiography is thus a useful technique for the diagnosis of biliary ascariasis

  5. Intrahepatic Duct Stones Harboring Ascariasis Ova: A Case Report.

    Lee, Chen-Fang; Lee, Wei-Chen; Wu, Ren-Chin; Chen, Tse-Ching

    2016-03-01

    Ascariasis lumbricoides is one of the most common helminthic infestations in humans. Despite the fact that the prevalence of ascariasis in developed countries has been decreasing, biliary ascariasis can cause serious complications, such as acute cholangitis, pancreatitis, and liver abscess. Here we presented a rare ascariasis-related complication-hepatolithiasis.A 60-year-old female patient had symptoms of recurrent cholangitis. Abdominal computed tomography scan revealed left intrahepatic duct stones with left liver lobe atrophy. Endoscopic retrograde cholangiopancreatography was performed, but the stones could not be removed due to left main intrahepatic duct stenosis. The patient was treated with left hemi-hepatectomy. Unexpectedly, Ascaris ova were found on the histopathological examination. She received antihelminthic therapy orally and was on regular follow-up without any complications.Our study indicates that clinicians should be aware of biliary ascariasis in patients with hepatolithiasis, though not living in endemic areas. PMID:27015193

  6. Role of hepatobiliary scintigraphy in biliary ascariasis

    Following the introduction of immunodiacetic acid (IDA) compounds labelled with 99Tcm, hepatobiliary scintigraphy has successfully been used to identify a variety of hepatobiliary pathologies. This study deals with the scintigraphic findings in patients having involvement of the hepatobiliary system with ascariasis. Patients clinically suspected of having hepatobiliary pathology were routinely sent for radionuclide evaluation of the hepatobiliary system. 99Tcm HIDA, EHIDA or BULLIDA was injected under the gamma camera and one min frames were collected for 40 min over the abdominal region using an on-line computer. After the sequential study was over, if the gallbladder was not visualized, late pictures were taken until the gallbladder was seen or for 4 hours, whichever was earlier. When the gallbladder was visualized, post-fatty-meal images were made for visual analysis and time/activity curves were generated over regions of interest for further evaluation. Patients having total or partial subhepatic biliary channel obstruction with or without dilatation of intrahepatic ducts were subjected to endoscopic retrograde cholangio-pancreatography (ERCP) within the next two to three days. Out of 360 patients thus evaluated, 84 (23%) showed partial, total or near total subhepatic obstruction. In 55 cases the whole biliary tree was dilated; in 17 cases the left hepatic duct and the common bile duct (CBD); in seven cases the left hepatic duct alone, and in five cases the CBD alone. ERCP findings were concurrent in most cases. However, in 13 cases no abnormality of the biliary tree could be detected by ERCP, although worms were found in the duodenum. In 28 cases single or multiple worms were found inside the hepatobiliary channel. Video recordings of the ERCP revealed in some cases that the worms were moving in and out of the biliary channel. In 41 cases of proven biliary ascariasis, scintigraphic finding was indicative in all cases. Hepatobiliary scintigraphy appears to be a

  7. Acute pancreatitis due to ascariasis: a sonographic pictorial essay on four cases.

    Lynser, Donboklang; Thangkhiew, R S; Laloo, Demitrost; Hek, M D; Marbaniang, Evarisalin; Tariang, Satisfy

    2016-06-01

    Ascariasis is the commonest helminthic disease to infect humans. Due to their wandering nature, the roundworms from the second part of the duodenum migrate through the biliary opening into the hepatobiliary and pancreatic ducts. Ascariasis is the most common parasitic cause of pancreatitis in endemic region. Pancreatitis can result due to pancreatic ascariasis, biliary ascariasis or both. Pancreatitis due to ascariasis can be severe and life-threatening. We present a pictorial essay of acute pancreatitis due to ascariasis on four cases. PMID:27059341

  8. [Acute cholangitis secondary to ascariasis and complicated by liver abscesses].

    Rakotonaivo, A; Ranoharison, H D; Razarimahefa, S H; Rakotozafindrabe, R; Rabenjanahary, T H; Ramanampamonjy, R M

    2015-01-01

    Acute cholangitis secondary to ascariasis is rare and occurs mainly in areas of high endemicity. The clinical presentation is non-specific, sometimes complicated by liver abscess. Abdominal ultrasound plays an important role in diagnosis and therapeutic surveillance. We report the case of a 35-year-old Malagasy woman with an acute cholangitis secondary to ascariasis and complicated by liver abscesses and its course to full recovery under medical treatment. PMID:26742557

  9. Hepatolithiasis with biliary ascariasis – a case report

    Khithani AS; Shetty TS; Joshi RM; Amarapurkar AD; Pilankar KS; Chemburkar VV

    2003-01-01

    Abstract Background Biliary ascariasis is regarded as possible etiological factor for hepatolithiasis. Here we report one case of a patient with hepatolithiasis with biliary ascariasis who developed a liver abscess, which was treated with partial hepatectomy. Case presentation A young adult female presented with epigastric pain and vomiting with repeated attacks of cholangitis. ERCP showed evidence of multiple intrahepatic calculi with the development of abscess in the left lobe of liver. The...

  10. Biliary ascariasis in a bile duct stones-removed female patient

    2013-01-01

    Biliary ascariasis is a common problem in rural areas in China. The common presentations include biliary colic, acute cholangitis, obstructive jaundice, choledocholithiasis and acute cholecystitis. Here, we describe a case with biliary ascariasis two days after endoscopic sphincterotomy for choledocholithiasis. A living ascaris was successfully removed by endoscopic retrograde cholangiopancreatography. This case indicated that biliary ascariasis is not an uncommon complication of endoscopic s...

  11. 3 T MR cholangiopancreatography appearances of biliary ascariasis

    Ding, Z.X., E-mail: hangzhoudzx73@126.co [Department of Radiology, Zhejiang Provincial People' s Hospital, Hangzhou (China); Yuan, J.H. [Department of Radiology, Zhejiang Provincial People' s Hospital, Hangzhou (China); Chong, V. [Department of Diagnostic Imaging, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore (Singapore); Zhao, D.J. [Department of Hepatobiliary Surgery, Zhejiang Provincial People' s Hospital, Hangzhou (China); Chen, F.H.; Li, Y.M. [Department of Radiology, Zhejiang Provincial People' s Hospital, Hangzhou (China)

    2011-03-15

    Aim: To evaluate the 3 T MR cholangiopancreatography (MRCP) appearances of biliary ascariasis. Materials and methods: Nine patients with a MRCP diagnosis of biliary ascariasis were reviewed. All patients had endoscopic retrograde cholangiopancreatography (ERCP) or surgical confirmation of the disease. Results: On thin-slab MRCP imaging, Ascaris worms are clearly demarcated within the biliary tree. All the identified worms demonstrated a characteristic three-parallel-lines appearance. The middle high-signal intensity line is sandwiched between two low-signal intensity lines and they are in turn surrounded by high signal bile. On thick-slab MRCP the worms also show the three-line sign but with less clarity. However, thick-slab MRCP has the advantage of providing three-dimensional ERCP-like images of the pancreaticobiliary system. Conclusion: The 'three-line' sign appears to be a characteristic sign of biliary ascariasis on 3 T MRCP.

  12. 3 T MR cholangiopancreatography appearances of biliary ascariasis

    Aim: To evaluate the 3 T MR cholangiopancreatography (MRCP) appearances of biliary ascariasis. Materials and methods: Nine patients with a MRCP diagnosis of biliary ascariasis were reviewed. All patients had endoscopic retrograde cholangiopancreatography (ERCP) or surgical confirmation of the disease. Results: On thin-slab MRCP imaging, Ascaris worms are clearly demarcated within the biliary tree. All the identified worms demonstrated a characteristic three-parallel-lines appearance. The middle high-signal intensity line is sandwiched between two low-signal intensity lines and they are in turn surrounded by high signal bile. On thick-slab MRCP the worms also show the three-line sign but with less clarity. However, thick-slab MRCP has the advantage of providing three-dimensional ERCP-like images of the pancreaticobiliary system. Conclusion: The 'three-line' sign appears to be a characteristic sign of biliary ascariasis on 3 T MRCP.

  13. A report of two cases of ascariasis pancreatitis managed conservatively

    Darlong, Laleng M.; Rubul Das; Ranendra Hajong; Noor Topno

    2011-01-01

    Ascaris lumbricoides is a common intestinal parasite in tropical and temperate regions. Although usually asymptomatic, infection can lead to biliary or intestinal obstruction and very rarely obstruction of the main pancreatic duct due to its smaller lumen. We report two cases of ascariasis in the main pancreatic duct, which is not a common site, presenting as acute pancreatitis and recovering uneventfully with conservative management.

  14. Sonographic images of hepato-pancreatico-biliary and intestinal ascariasis: A pictorial review

    Lynser, Donboklang; Handique, Akash; Daniala, Chhunthang; Phukan, Pranjal; Marbaniang, Evarisalin

    2015-01-01

    Abstract Despite advancement in the diagnosis and treatment of intestinal helminthiasis, ascariasis remains the most common cause of helminthic infections in the developing countries. Ultrasound offers a rapid, safe, and noninvasive approach to the diagnosis of intestinal ascariasis. Ultrasound is also the modality of choice for diagnosis of hepatobiliary ascariasis, which is relatively rare and is due to migration of intestinal worms through the papilla of Vater. We present an imaging spectr...

  15. Biliary Ascariasis in the Indian Subcontinent: A Study of 42 Cases

    Mukhopadhyay Madhumita

    2009-01-01

    Background/Aim: History of ascariasis is known to stretch back many centuries. One quarter of the world′s population is known to be infected by ascariasis. It is endemic in various parts of the Indian subcontinent and the gangetic plain of West Bengal is one of them. We aimed to study the various types of clinical presentations, complications and different diagnostic tools and to assess various options for the management of biliary ascariasis. Materials and Methods: Forty-two cases ...

  16. ASCARIASIS AND COEXISTANT STONE IN COMMON BILE DUCT IN POST CHOLECYSTECTOMY POST CHOLEDOCHOLITHOTOMY WOMAN: A CASE REPORT

    Khalid

    2014-11-01

    Full Text Available Ascariasis is one of the commonest infections in Asia. Biliary ascariasis is a serious presentation of ascariasis which can result in life threatening complications including cholangitis, choledocholithiasis, Liver abscess, and Pancreatitis. We present a case of female from north Bihar who presented to us with biliary ascariasis and concomitant stone. Diagnosis was established by abdominal ultrasonography. Choledocholithotomy done and a live round worm with two biliary stone extracted.

  17. ASCARIASIS AND COEXISTANT STONE IN COMMON BILE DUCT IN POST CHOLECYSTECTOMY POST CHOLEDOCHOLITHOTOMY WOMAN: A CASE REPORT

    Khalid,; Mahendra; Pradeep; Krishna; Vibhuti; Haque; Sanjay; Vijayanand,; Sangeeta

    2014-01-01

    Ascariasis is one of the commonest infections in Asia. Biliary ascariasis is a serious presentation of ascariasis which can result in life threatening complications including cholangitis, choledocholithiasis, Liver abscess, and Pancreatitis. We present a case of female from north Bihar who presented to us with biliary ascariasis and concomitant stone. Diagnosis was established by abdominal ultrasonography. Choledocholithotomy done and a live round worm with two biliary stone ...

  18. A report of two cases of ascariasis pancreatitis managed conservatively

    Laleng M Darlong

    2011-01-01

    Full Text Available Ascaris lumbricoides is a common intestinal parasite in tropical and temperate regions. Although usually asymptomatic, infection can lead to biliary or intestinal obstruction and very rarely obstruction of the main pancreatic duct due to its smaller lumen. We report two cases of ascariasis in the main pancreatic duct, which is not a common site, presenting as acute pancreatitis and recovering uneventfully with conservative management.

  19. Gangrenous Meckel's diverticulum secondary to ascariasis in a child

    Akhtar, Tanveer; Alladi, Anand; Siddappa, OS; Bahubali, G

    2012-01-01

    Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract, which is usually asymptomatic. In patients with intestinal ascariasis, Meckel's diverticulum may pursue a silent course or may be complicated by diverticulitis, gangrene and perforation. We report an unusual complication of volvulus of Meckel's diverticulum and an adjacent segment of ileum due to incarceration of worm bolus in a narrow based Meckel's diverticulum leading to gangrene and perforation.

  20. Biliary ascariasis: Report of a complicated case and literature review

    Sanai F; Al-Karawi M

    2007-01-01

    Invasion of the Ascaris worm into the biliary system leads to a wide variety of clinical syndromes. Most of the descriptions of the disease have originated from the developing world, where due to the environmental factors there is a high level of parasitism. An increased incidence of biliary ascariasis borne out of population migration and increased facilities for diagnosis has led to a renewal of interest in this disease in the developed world. Significant morbidity and mortality is associat...

  1. An unusual case of ascariasis of the appendix

    Paganelli Arnaldo; Krstić Slobodan; Ivanov Dejan; Anđelkov Katarina; Zaccheddu Renato; Sforza Marcos

    2011-01-01

    Introduction. Amongst various causes responsible for the obstruction of digestive tract, intestinal ascariasis is certainly one of the least frequent. Case Outline. We report an extremely rare case of a 5-year-old male patient operated on for appendicitis due to adult Ascaris Lumbricoides worms intraoperatively detected in the appendiceal lumen. Conclusion. On examination patient’s clinical features indicated acute appendicitis. Therefore, the treatment-of-choice could only be surgical....

  2. Acute Lower Gastrointestinal Haemorrhage Secondary to Small Bowel Ascariasis

    Daphne Dewi, Stephen; Sze Li, Siow

    2012-01-01

    Acute lower gastrointestinal haemorrhage secondary to small bowel ascariasis is extremely rare. A high level of suspicion should be maintained when dealing with acute gastrointestinal haemorrhage in migrants and travellers. Small bowel examination is warranted when carefully repeated upper and lower endoscopies have failed to elicit the source of bleeding. Appropriate test selection is determined by the availability of local expertise. We present a case of acute lower gastrointestinal haemorr...

  3. Radio-pathological diagnosis of hepatobiliary ascariasis: A rare entity

    Indranil Chakrabarti; Amita Giri; De, Anuradha; Asit Chandra Roy

    2011-01-01

    Ascariasis is the commonest helminthic infection in humans, caused by the nematode Ascaris lumbricoides. The adult worms usually reside in the small intestine. Rarely, they migrate into the bile duct and pancreatic ducts, but involvement of the gall bladder and/or liver parenchyma is extremely rare. Here, we describe a case of a 32-year-old woman who presented with fever, anorexia, right upper quadrant pain and mild hepatomegaly. Ultrasonography revealed a liver abscess and a concurrent movin...

  4. Ascariasis of gall bladder associated with xanthogranulomatous inflammation and cholelithiasis

    Deshmukh, Sanjay D; Pathak, Gayatri S; Ashturkar, Amrut V; Avinash R Joshi; Shelke, Rahul R

    2011-01-01

    We report a rare case of ascariasis of gall bladder. The unusual features in this case were the presence of eggs of Ascaris lumbricoides in the lumen. Some of the eggs had evoked a foreign body reaction indicating chronicity. The bladder wall was unevenly thickened with yellowish white nodules and showed maximum thickness around the neck region. Microscopy showed predominantly xanthogranulomatous inflammation in the thickened parts of the wall.

  5. Periampullary carcinoma following biliary ascariasis--a case report.

    Chowdhury T; Dubey S

    1997-01-01

    A 42 year old man presented with obstructive jaundice and cholangits. Ultrasonography (USG) revealed dilated intrahepatic biliary radicals and common bile duct (CBD). The bile duct also showed a curvilinear parallel intraluminal structure suggesting biliary ascariasis. The CBD was explored and a dead worm removed but jaundice persisted. Endoscopic retrograde cholangio pancreaticography (ERCP) was done showing a periampullary mass which on biopsy showed a villous adenoma with highly dysplastic...

  6. Ascariasis Presenting as Acute Abdomen—A Case Report

    Nag, Hirdaya H.; Ji, Ram

    2012-01-01

    Infection with Ascaris lumbricoides is common in tropical and subtropical regions of the world. Prevalence of ascariasis is related to poverty, poor hygiene and poor fecal sanitation. This helminth usually lives harmlessly in small intestine but can also cause intestinal obstruction or perforation peritonitis which is common in childhood. Ascaris can also migrate through ampulla of vater to produce cholangitis, pancreatitis,cholecystitis and rarely hepatic abscess. Ascaris induced hepatic abs...

  7. Real-time ultrasonographic findings of biliary ascariasis

    Woo, Seong Ku; Sung, Dong Wook; Ko, Young Tae; Kim, Ho Kyun; Kim, Soon Yong [Kyung Hee University Hospital, Seoul (Korea, Republic of)

    1983-06-15

    Although the ultrasonography has been regarded as a main procedure in the diagnosis of bile duct and gallbladder diseases, a few reports concerning the ultrasonographic findings of biliary ascariasis appeared in the literature. Seven cases of real-time ultrasonographic diagnosis of biliary ascariasis were made in our hospital during last 15 months. In six, the diagnosis was confirmed by surgery or radiographic examination. The results were as follows: 1. The characteristic long, thick, highly reflective echo without distal acoustic shadowing in the extra- and/or intra-hepatic ducts were seen in all six proven cases. 2. The echogenic, nonshadowing images of the worms were seen as single stripe in five cases (containing a central, longitudinal, anechoic tube, suggesting its digestive tract in three cases) or multiple stripes in one case. But so-called coiled appearance or amorphous fragments were not seen in our cases. 3. Associated findings were as follows: mild to moderate dilatation of the extrahepatic duct in all six proven cases, mild dilatation of the intrahepatic ducts in 3 cases, mild dilatation of the pancreatic duct in 1 case, intrahepatic stone in 1 case, contracted gallbladder containing single stone in 1 case and evidence of cholecystitis in 4 cases. 4. One false positive diagnosis of ascariasis in the gallbladder is considered due to reverberation artefact. No false negative was seen.

  8. Real-time ultrasonographic findings of biliary ascariasis

    Although the ultrasonography has been regarded as a main procedure in the diagnosis of bile duct and gallbladder diseases, a few reports concerning the ultrasonographic findings of biliary ascariasis appeared in the literature. Seven cases of real-time ultrasonographic diagnosis of biliary ascariasis were made in our hospital during last 15 months. In six, the diagnosis was confirmed by surgery or radiographic examination. The results were as follows: 1. The characteristic long, thick, highly reflective echo without distal acoustic shadowing in the extra- and/or intra-hepatic ducts were seen in all six proven cases. 2. The echogenic, nonshadowing images of the worms were seen as single stripe in five cases (containing a central, longitudinal, anechoic tube, suggesting its digestive tract in three cases) or multiple stripes in one case. But so-called coiled appearance or amorphous fragments were not seen in our cases. 3. Associated findings were as follows: mild to moderate dilatation of the extrahepatic duct in all six proven cases, mild dilatation of the intrahepatic ducts in 3 cases, mild dilatation of the pancreatic duct in 1 case, intrahepatic stone in 1 case, contracted gallbladder containing single stone in 1 case and evidence of cholecystitis in 4 cases. 4. One false positive diagnosis of ascariasis in the gallbladder is considered due to reverberation artefact. No false negative was seen

  9. Ascariasis as a cause of recurrent abdominal pain.

    Guzman, Gerly Edson; Teves, Pedro Montes; Monge, Eduardo

    2010-04-01

    Ascariasis is the most common helminthic infection in developing countries. It may cause chronic abdominal pain, tenderness and bloating. Our aim is to report a case of acute episodic abdominal pain and pancreatitis associated with ascariasis. We report a 59-year-old female patient who was admitted for acute abdominal pain, having had several previous similar events before one of them was diagnosed as acute idiopathic pancreatitis. On admission, her physical exam was normal. Laboratory results showed hemoglobin 12.2 g/dL, white blood cell count 11 900 cells/mm(3), eosinophils 420 cells/mm(3), serum amylase 84 IU/mL, lipase 22 IU/mL and normal liver function tests. Abdominal ultrasound and a plain abdominal X-ray were also normal. An upper endoscopy showed round white worms in the duodenum and the stomach, some of them with bile in their intestines. The intestinal parasites were diagnosed as Ascaris lumbricoides, and the patient was started on albendazole, with full recovery within a week. We believe that ascariasis should be considered in patients with recurrent abdominal pain and idiopathic pancreatitis. PMID:20447214

  10. [Three recent cases of ascariasis in northern Kyushu].

    Makiya, K; Tsukamoto, M; Unoki, H; Sujita, K; Mori, N; Miki, T; Yokoyama, M

    1988-03-01

    Ascariasis is considered to be one of the rare infectious diseases in Japan, but recently it has been slightly increasing. This paper reports three ascariasis cases who seemed to be infected recently in the Kitakyushu area, Japan. Case 1: A 59-year-old woman in Kitakyushu City passed a round worm after continuous abdominal pain. The patient was discharged from the hospital because of no further abnormal intestinal symptoms and findings. Case 2: An 85-year-old woman in Nakama City, who suffered from cerebral infarction, vomited a round worm before hospitalization. Many ascarid eggs were detected after admission, and after treatment with pyrantel pamoate (Combantrin) two round worms were passed and egg detection became negative. Case 3: A 77-year-old man in Saikawa Town vomited 3 round worms after gastrectomy due to early gastric cancer. Many unfertilized eggs were also detected from the stool together with hook worm eggs, but no eggs were found after administration of pyrantel pamoate. Morphological examination was made by a scanning electron microscope on the denticles on the dentigerous lip ridges of the worms to differentiate from possible infection with a pig parasite, Ascaris suum. The three cases were diagnosed as ascariasis due to human Ascaris lumbricoides based on the following evidences that the expelled worms had 1) less pointed tips of the denticles and shallower or wider interdenticle notches, and 2) far more denticles of smaller size along the dentigerous ridges, compared with Ascaris suum. The necessity of differentiating pig- from human-ascarids, when considering human infection with Ascaris suum, is discussed. PMID:3368668

  11. Gastro-intestinal ascariasis--an unusual autopsy case report.

    Kanchan, Tanuj; Wasti, Harihar; Acharya, Jenash

    2015-09-01

    Ascaris lumbricoides or roundworms' propensity to produce large number of eggs that are resistant to extremes of environmental conditions have made them one of the highly prevalent and geographically well distributed nematodes among poor socio-economic regions throughout the world. We present an unusual case of fatal gastro-intestinal ascariasis where general neglect, and firm and prolonged reliance on traditional healing methods led to aggregation of roundworms to such an extent that otherwise seems improbable in modern times and, hence, is worth reporting. PMID:25748290

  12. Clinical features and management of biliary ascariasis in a non-endemic area

    Misra, S; Dwivedi, M.

    2000-01-01

    Biliary ascariasis is common in certain geographical areas of the world. In India, it is common in the Kashmir valley and only stray cases have been reported from other parts of the country. Between January 1995 and May 1997, 14 patients with biliary ascariasis were seen at our centre, which is more than 1000 km from the Kashmir valley. The mean (± SD) age of the patients was 31.7 (± 6.1) years and all were females. None of them had been to a place known to be endemic for biliary ascariasis. ...

  13. Intestinal ascariasis at pediatric emergency room in a developed country.

    Umetsu, Shuichiro; Sogo, Tsuyoshi; Iwasawa, Kentaro; Kondo, Takeo; Tsunoda, Tomoyuki; Oikawa-Kawamoto, Manari; Komatsu, Haruki; Inui, Ayano; Fujisawa, Tomoo

    2014-10-14

    Ascaris lumbricoides infection is rare among children in developed countries. Although large numbers of adult Ascaris in the small intestine can cause various abdominal symptoms, this infection remains asymptomatic until the number of worms in the intestine considerably increases in most cases. Ascaris causing bilious vomiting suggesting ileus is rare, especially in developed countries. A 6-year-old boy who lived in Japan, presented with abdominal colic, bilious vomiting at the pediatric emergency room. He appeared pale, and had no abdominal distention, tenderness, palpable abdominal mass, or findings of dehydration. He experienced bilious vomiting again during a physical examination. Laboratory tests showed mild elevation of white blood cells and C-reactive protein levels. Antigens of adenovirus, rotavirus, and norovirus were not detected from his stool, and stool culture showed normal flora. Ultrasonography showed multiple, round-shaped structures within the small intestine, and a tubular structure in a longitudinal scan of the small intestine. Capsule endoscopy showed a moving worm of Ascaris in the jejunum. Intestinal ascariasis should be considered as a cause of bilious vomiting in children, even at the emergency room in industrial countries. Ultrasound examination and capsule endoscopy are useful for diagnosis of pediatric intestinal ascariasis. PMID:25320546

  14. Ascariasis as a cause of hepatic abscess: A report of 3 cases

    Chauhan, V; Thakur, S; Rana, B

    2015-01-01

    We receive around 60 cases of hepatic abscess in a year. The commonest diagnosis reached at the time of discharge is amoebic liver abscess. The diagnosis of amoebic liver abscess is mostly presumptive and thus the patients are usually given a mixed treatment with injection ceftriaxone and tablet metronidazole. Here we report three cases of hepatic abscess diagnosed recently, where ascariasis was the probable etiology. Ascariasis may be a much commoner cause of hepatic abscesses in this region...

  15. Ascariasis as a cause of hepatic abscess: A report of 3 cases.

    Chauhan, V; Thakur, S; Rana, B

    2015-01-01

    We receive around 60 cases of hepatic abscess in a year. The commonest diagnosis reached at the time of discharge is amoebic liver abscess. The diagnosis of amoebic liver abscess is mostly presumptive and thus the patients are usually given a mixed treatment with injection ceftriaxone and tablet metronidazole. Here we report three cases of hepatic abscess diagnosed recently, where ascariasis was the probable etiology. Ascariasis may be a much commoner cause of hepatic abscesses in this region than we think. PMID:26068350

  16. Comparative Study on Presentation of Biliary Ascariasis with Dead and Living Worms

    Alam, Shahinul; Mustafa, Golam; Rahman, Salimur; Kabir, Shamsul A.; Rashid, Harun O.; Khan, Mobin

    2010-01-01

    Background/Aim: Ascariasis is a common parasitic infestation in Asia and Latin America. The most serious presentation is biliary and pancreatic ascariasis (BPA). The aim of the present study was to compare the clinical presentation of BPA with dead worms with that with living worms. Materials and Methods: We included 138 consecutive cases of BPA that occured during the period January 2005 to July 2009. All the patients had endoscopically proven BPA consisting of living or dead worms. Comparis...

  17. A cause of obstructive icter: Ascariasis and endoscopic treatment (biliary acariasis and treatment)

    GÜRSOY, Şebnem; BAŞKOL, Mevlüt; YURCİ, Alper; GÜVEN, Kadri; ÖZBAKIR, Ömer; YÜCESOY, Mehmet

    2004-01-01

    Ascariasis is one of the most common helmintic diseases. Biliary ascariasis is less frequent but important because of its complications. In this paper, we present a patient who admitted to our clinic with the complaints of abdominal pain and progressive icterus. His liver function tests were abnormal. Abdominal ultrasonography was compatible with cholangitis and possible parasitic infection of biliary ducts. ERCP was performed and several ascaris worms were seen at the papilla. Endosco...

  18. The Efficacy of Single-Dose Albendazole for The Treatment of Ascariasis

    Putra, Deddy S.; Dalimunthe, W.; Lubis, M.; Pasaribu, S.; Lubis, Chairuddin P.

    2005-01-01

    Objective This study aims to assess the efficacy of single-dose albendazole in treating mild, moderate, and severe ascariasis. Methods Stool specimens were collected from randomly selected elementary school children in Suka village, Sumatera Utara, from March to April 2002. Based on the number of eggs per gram feces (NEPG), samples were categorized as mild (NEPG 35,000) ascariasis. All subjects then received 400 mg albendazole orally....

  19. Hepatobiliary and pancreatic ascariasis-sonographic pictorial essay on four pediatric cases with acute biliary colic.

    Lynser, Donboklang; Marbaniang, Evarisalin

    2016-04-01

    Hepatobiliary and pancreatic ascariasis occur due to migration of the round worm ascaris lumbricoides through the bile duct orifice finally reaching the common bile duct, main pancreatic duct, intrahepatic ducts or gallbladder. These resulted in acute epigastric and right hypochondriac region colicky pain. Ultrasound is the investigation of choice in hepatobiliary ascariasis. We present here sonographic images on four pediatric patients with acute biliary colic. PMID:26690772

  20. Ascariasis of the gall bladder. Report of two cases.

    Dantas, W; Salles, C G

    1976-01-01

    A radiological diagnosis of ascariasis of the gallbladder was made in two middle-aged women with high abdominal pain having biliary colic characteristics. In one case round worm was demonstrated by means of the intravenous cholangiography, but in the other the procedure was negative only the common bile duct being contrasted. Oral cholangiography made some days later permitted the visualization of the parasite in the gallbladder. The patients were treated by cholecistectomy and choledocostomy and the diagnosis was confirmed. The post-operative course was uneventful. There was Ascaris lumbricoides ova in the feces and the histological examination of the removed gallbladder showed large eosinophilic infiltration in both cases. The patients received levamisole some days after surgery. PMID:829874

  1. An alien in the gallbladder. A rare case of biliary ascariasis in an Italian emergency department

    Enrico Ferri

    2016-04-01

    Full Text Available Ascariasis is a common infection in many developing countries. The prevalence of ascariasis is related to poverty, poor hygienic and sanitary conditions. The adult form of Ascaris lumbricoides usually resides in the human intestinal lumen (more frequently in the jejunum and middle ileum and does not cause symptoms. However, it can occasionally cause severe complications such as intestinal obstruction or perforation peritonitis. Its migration into the biliary tract is not uncommon but gallbladder involvement is very rare. Abdominal ultrasonography is essential to detect the presence of this parasite. In this article, we describe the radiologic findings, clinical manifestations and successful medical treatment of a patient with gallbladder ascariasis diagnosed in an emergency setting.

  2. Biliary ascariasis in the Indian subcontinent: A study of 42 cases

    Mukhopadhyay Madhumita

    2009-01-01

    Full Text Available Background/Aim: History of ascariasis is known to stretch back many centuries. One quarter of the world′s population is known to be infected by ascariasis. It is endemic in various parts of the Indian subcontinent and the gangetic plain of West Bengal is one of them. We aimed to study the various types of clinical presentations, complications and different diagnostic tools and to assess various options for the management of biliary ascariasis. Materials and Methods: Forty-two cases of hepatobiliary ascariasis were studied over a period of 3 years. All the patients were adults aged between 20 and 50 years and all but two were admitted with acute upper abdominal pain. Results: In this study, biliary ascariasis was found to be more common in females, 73.8% (31 patients. The most common presentation was upper abdominal pain in 95.2% of the patients (40 patients. Complications observed were obstructive jaundice in 28.56% (12 patients, cholangitis in 16.7% (seven patients, acute pancreatitis in 2.4% (one patient and hepatic abscess in 2.4% (one patient. History of worm emesis was present in 38.1% (16 patients. History of previous cholecystectomy was present in 16.7% (seven patients and endoscopic sphincterotomy in 4.8% (two patients. Ultrasound was the diagnostic tool of choice with 100% results. Conservative management was successful in 83.3% (35 patients. During follow-up, worm reinvasion of the biliary system occurred in 7.1% (three patients. Conclusion: In endemic countries, ascariasis should be suspected in patients with biliary disease, especially if a cholecystectomy or sphincterotomy has been performed in the past. Most of the patients respond to conservative management.

  3. Ascariasis as a cause of hepatic abscess: A report of 3 cases

    V Chauhan

    2015-01-01

    Full Text Available We receive around 60 cases of hepatic abscess in a year. The commonest diagnosis reached at the time of discharge is amoebic liver abscess. The diagnosis of amoebic liver abscess is mostly presumptive and thus the patients are usually given a mixed treatment with injection ceftriaxone and tablet metronidazole. Here we report three cases of hepatic abscess diagnosed recently, where ascariasis was the probable etiology. Ascariasis may be a much commoner cause of hepatic abscesses in this region than we think.

  4. Ascariasis in humans and pigs on small-scale farms, Maine, USA, 2010-2013.

    Miller, Leigh Ann; Colby, Kate; Manning, Susan E; Hoenig, Donald; McEvoy, Elizabeth; Montgomery, Susan; Mathison, Blaine; de Almeida, Marcos; Bishop, Henry; Dasilva, Alexandre; Sears, Stephen

    2015-02-01

    Ascaris is a genus of parasitic nematodes that can cause infections in humans and pigs. During 2010-2013, we identified 14 cases of ascariasis in persons who had contact with pigs in Maine, USA. Ascaris spp. are important zoonotic pathogens, and prevention measures are needed, including health education, farming practice improvements, and personal and food hygiene. PMID:25626125

  5. Ascariasis in Humans and Pigs on Small-Scale Farms, Maine, USA, 2010–2013

    Miller, Leigh Ann; Colby, Kate; Manning, Susan E.; Hoenig, Donald; McEvoy, Elizabeth; Montgomery, Susan; Mathison, Blaine; de Almeida, Marcos; Bishop, Henry; DaSilva, Alexandre; Sears, Stephen

    2015-01-01

    Ascaris is a genus of parasitic nematodes that can cause infections in humans and pigs. During 2010–2013, we identified 14 cases of ascariasis in persons who had contact with pigs in Maine, USA. Ascaris spp. are important zoonotic pathogens, and prevention measures are needed, including health education, farming practice improvements, and personal and food hygiene.

  6. Ascariasis as an Unexpected Cause of Acute Pancreatitis with Cholangitis: A Rare Case Report from Urban Area

    Pochamana Phisalprapa; Varayu Prachayakul

    2013-01-01

    Context Ascaris lumbricoides is one of the most common parasitic infestations of human gastrointestinal tract. This parasiticinfestation might be asymptomatic and only few studies on extraintestinal ascariasis have been reported. Ascending cholangitis and acute pancreatitis as a result of the Ascaris lumbricoides migrating into the biliary system and pancreatic duct were very rare complications. Here, we presented a case report of biliary ascariasis induced acute pancreatitis with cholangitis...

  7. Endoscopy treatment of multiple ascariasis biliary in children Cases report and review

    The Ascaridiasis is a problem of public health in the most countries located in the third world, one of the most common presentations of this parasitism is the biliary erratic ascariasis, which involves the biliary ways and the pancreatic conduit, although most of the research works report about the low incidence of this pathology in kids. In the present Article we report five cases of kids with a manifestation of ascariasis in common bile duct, four of them are the most interesting cases due to the presence of multiple biliary parasites. Once a revision made of paraclinical reports of these five cases and the characteristics of the E.R.C.P endoscopic procedure, we are showing the advantages of this method for the diagnostic and treatment of this pathology at the same time it is exposed to the readers a brief actualization of this infestations

  8. Evaluation of two years of mass chemotherapy against ascariasis in Hamadan, Islamic Republic of Iran.

    2002-01-01

    OBJECTIVE: To evaluate the mass treatment of ascariasis in rural areas of Hamadan Province, Islamic Republic of Iran. METHODS: A control programme in rural areas of Hamadan Province, which began in November 1997, involved giving all persons a single dose of 400 mg albendazole at intervals of three months. The efficacy of the treatment was evaluated by the formalin-ether concentration technique for stool examination and by the Stoll quantitative method. FINDINGS: The average rate of infection ...

  9. Effects of improved water supply and sanitation on ascariasis, diarrhoea, dracunculiasis, hookworm infection, schistosomiasis, and trachoma.

    Esrey, S. A.; Potash, J. B.; Roberts, L.; Shiff, C.

    1991-01-01

    A total of 144 studies were analysed to examine the impact of improved water supply and sanitation facilities on ascariasis, diarrhoea, dracunculiasis, hookworm infection, schistosomiasis, and trachoma. These diseases were selected because they are widespread and illustrate the variety of mechanisms through which improved water and sanitation can protect people. Disease-specific median reduction levels were calculated for all studies, and separately for the more methodologically rigorous ones...

  10. Ultrasonography findings of biliary ascariasis as a rare cause of acalculous cholecystitis

    Şalk, İsmail; Atalar, Mehmet H.

    2014-01-01

    AbstractAscaris lumbricoides is the most common intestinal parasite to infect humans. The incidence of ascariasis is increasing in all part of the world because of world travel and population migration. Ascaris lumbricoides may cause various complications in the gastrointestinal system. Abdominal pain and tenderness with weight loss are the most common clinical presentations. The parasite can cause invagination at the intestinal segments and can enter the bile duct and cause cholangitis or bi...

  11. Epidemiological Study of Ascariasis in Hamadan City , West of Iran, 2001

    M. Fallah

    2004-04-01

    Full Text Available Ascaris lumbricoides is the most common intestinal parasite in the world. Various studies has indicated the high prevalence of this parasite in Iran, specially in the west parts of Iran. The epidemiological study of intestinal parasitic infection is prerequisite for planning of control programs. The Hamadan province is one of the most tourist attraction regions of Iran and providing a safe environment for travelers is the main aim of regional authorities. A mass chemotherapy for Ascariasis performed in rural areas of Hamadan province for a five years period but, no any intervention was done for control of this parasite in the Hamadan city. Therefore, an epidemiological study of Ascariasis in this town was necessary. A cross sectional study carried out by cluster random sampling in Hamadan and 580 stool specimens collected from different parts of city. The stools were examined by formalin ether concentration technique for ova and parasites and intensity of infection was determined by quantitative modified Stoll method. Mean infection rate of Ascariasis was 19.5%. The Farhangian suburb (northern part had higher infection rate than other parts(28.5% and central parts of city showed lower infection rate(12.7%. The highest infection rate were found in the 31-40 years age group (33.8% and in the females(23.9%.In view of intensity, 59.3% of infections were moderate and 48.3% had low intensity. No any high intensity were found. Mean egg per gram(epg were 7129 and 48.7% of eggs were infertile. This study indicated that , prevalence of Ascaris in Hamadan city is considerable at present and a suitable intervention, like health education and selective chemotherapy is necessary to decrease the infection.

  12. Comparative study on presentation of biliary ascariasis with dead and living worms

    Alam Shahinul

    2010-01-01

    Full Text Available Background/Aim: Ascariasis is a common parasitic infestation in Asia and Latin America. The most serious presentation is biliary and pancreatic ascariasis (BPA. The aim of the present study was to compare the clinical presentation of BPA with dead worms with that with living worms. Materials and Methods: We included 138 consecutive cases of BPA that occured during the period January 2005 to July 2009. All the patients had endoscopically proven BPA consisting of living or dead worms. Comparison was done by chi-square and independent t tests. Results: The age (mean ± SD of the patients was 36.8 ± 16.1 years. Prevalence ratio between male and female patients was 1:5. Ninety eight patients contained living worms and 40 had dead worms. Males were more prone to develop dead worm BPA. The commonest presentation was biliary colic (131; 94.9%; others were acute cholangitis (30; 21.7%, obstructive jaundice (19; 13.8%, choledocholithiasis (20; 14.5%, acute pancreatitis (10; 7.2%, acute cholecystitis (6; 4.3%, liver abscess (2; 1.4%, hepatolithiasis (3; 2.2%, stricture of common bile duct (2; 1.4%, pancreatic abscess (1; 0.7% and cirrhosis of liver (1; 0.7%. Choledocholithiasis, hepatolithiasis, liver abscess and cirrhosis were associated only with dead worms. We could successfully remove all the worms with endoscopic interventions, but 5 patients required surgical intervention as there were strictures and stones within the biliary tree or Ascaris were in gallbladder. Recurrences of stone and cholangitis occurred only in those with dead worms. Conclusion: Biliary ascariasis with dead worms is more dangerous than that with living worms. Endoscopic or surgical intervention may be required repeatedly in those with dead worms.

  13. Control of ascariasis through age-targeted chemotherapy: impact of 6-monthly chemotherapeutic regimens.

    Thein-Hlaing; Than-Saw; Myat-Lay-Kyin

    1990-01-01

    A field trial of 6-monthly ascariasis chemotherapeutic regimens targeted at 1-19-, 1-14-, and 5-19-year-olds was carried out in three communities in rural Myanmar to observe the effects on the prevalence, intensity, and morbidity indicators over 2 years. After periodic chemotherapy, the prevalence and intensity of Ascaris infection in age-targeted and non-age-targeted groups fell in all the study areas, more markedly among the 1-19- and 1-14-year-olds. There was also a decrease in the frequen...

  14. A critical assessment of abattoir surveillance as a screening test for swine ascariasis.

    Bernardo, T M; Dohoo, I R; Ogilvie, T

    1990-01-01

    The following data on ascarid burden were collected on an individual basis for 380 hogs marketed in the fall of 1987: a series of fecal ascarid-egg counts during the growing period; the level of milk spot lesions on the liver at slaughter; and the number of ascarids in the small intestines at slaughter. The presence of milk spots had a high sensitivity, very low specificity, and a high negative predictive value as a screening test for ascariasis in individual hogs. Results were consistent whe...

  15. Biliary ascariasis: the value of ultrasound in the diagnosis and management

    Conventional methods of radiographic examination are often unsatisfactory for identifying worms in the biliary tract. Ultrasonography is a non-invasive, quick and safe procedure known to have diagnostic accuracy. We studied the ultrasonographic appearance of biliary ascariasis and the role of ultrasonography in diagnosis and management. In a prospective 5-year study, a sonogarphic diagnosis of biliary ascariasis was made on 46 Yemeni patients. The diagnosis was based mainly on sonographic appearences supported by clinical and laboratory results and proved by outcome of either surgical or medical management or spontaneous exit of worms. Follow-up ultrasound was performed, for all patients, to confirm the diagnosis and to monitor the management. Parasites were present in the dilated main bile duct in 23 patients, in the gallbladder in 12 patients, in the intrahepatic ducts in 6 patients, in the main pancreatic duct in 4 patients and as an intrahepatic abscess in one patient. The characteristic appearance of Ascaris lumbricoides was a single or multiple echogenic non-shadowing linear or curved strips with or without echoic tubular central lines that represent the digestive tracts of the worm. A spaghetti-like appearance was seen in 9 patients and amorphous fragments were seen in 2 patients. Sixteen patients underwent surgery, 20 patients were treated medically (including spontaneous exit of the worm in 7 patients without treatment) and in 10 patients worms were extracted by endoscopic retrograde cholangiopancreatography. Follow-up ultrasound was found to be effective in confirming the diagnosis and monitoring management. (author)

  16. [Ascariasis: comparison of the therapeutic efficacy between paico and albendazole in children from Huaraz].

    López De Guimaraes, D; Neyra Llanos, R S; Romero Acevedo, J H

    2001-01-01

    A therapeutical clinical trial was designed to study the effectiveness of Paico and Albendazole, for the treatment of ascariasis in a group of 60 children, between 3 and 14 years old, from a rural community in Huaraz. It was carried out between May and August, 2000. The sample was randomly divided into 30 cases for Paico and 30 for Albendazole, the criteria for entering the trial being a positive examination for Ascaris lumbricoides in feces. The treatment consisted in Paico juice: 1 ml/Kg for less than 10 Kg, and 2 ml/Kg in larger children, one dose before breakfast, for three consecutive days. The Albendazole was administered in a single dose of 400 mg in those over five years of age, and 200 mg in younger children. The effectiveness was evaluated qualitatively (the disappearance of the ascaris eggs from the feces) and quantitatively (decrease in the parasitic burden); in the stool examinations carried out in all cases on entering the study and 15 days after the treatment. All the stool samples were processed in the Referential Laboratory of the Regional Health Authority in Ancash. The qualitative effectiveness between Paico and Albendazole for the eradication of ascariasis was similar at 86.7%. The quantitative effectiveness was 59.5% for Paico and 58.3% for Albendazole. However, it was observed that, unlike Albedazole, Paico is 100% effective in the treatment of Hymenolepsis nana. Adverse effects were presented in 23.3% of the cases for both drugs. It is concluded that, although Paico and Albendazole have a similar effectiveness against Ascaris lumbricoides, Paico has the additional benefit of being effective against Hymenolepsis nana. PMID:11818981

  17. Ascaridíase hepatobiliar complicada por pneumonia lipoídica Hepatobiliary ascariasis complicated by lipoid pneumonia

    Lisieux Eyer de Jesus

    2008-06-01

    Full Text Available OBJETIVO: Apresentar um caso de ascaridíase hepatobiliar complicado por pneumonia lipoídica e discutir as implicações anestésicas envolvidas. DESCRIÇÃO DO CASO: Menina de dois anos de idade com ascaridíase hepatobiliar complicada por pneumonia lipoídica por aspiração e desnutrição grave, advinda de família em condições sociais precárias em zona rural, com quatro irmãos. Foi tratada com sucesso por uma combinação de lavados broncopulmonares sucessivos e cirurgia. COMENTÁRIOS: Ascaridíase biliar corresponde a cerca de 10% dos casos de complicações de ascaridíase. Apenas uma minoria precisa de tratamento cirúrgico. O uso de óleo mineral por via oral é um tratamento tradicional para a suboclusão intestinal pelo Ascaris lumbricoides, mas a broncoaspiração do óleo e a conseqüente pneumonia lipoídica representam um risco alto para o seu uso. Anestesia geral para laparotomia exploradora em pré-escolar desnutrido com pneumonia lipóide e ascaridíase biliar é uma situação pouco contemplada na literatura médica, o que exigiu um planejamento terapêutico específico.OBJECTIVE: To present a case of hepatobiliary ascariasis complicated by exogenous lipoid aspirative pneumonia and the anesthetic implications involved. CASE DESCRIPTION: We present a case of hepatobiliary ascariasis complicated by exogenous lipoid aspirative pneumonia and severe undernourishment in a two-year-old female from a five-children poor family from the Brazilian rural area. She was successfully treated by the association of repeated bronchopulmonary lavage and surgery. COMMENTS: Biliary ascariasis corresponds roughly to 10% of complicated ascariasis cases. Only a minority requires surgery. Mineral oil is a traditional treatment for intestinal Ascaris lumbricoides subocclusion, but oil aspiration and lipoid pneumonia remain a highly morbid risk of this practice. General anesthesia and laparotomy in an undernourished small child with lipoid

  18. Barium X-ray diagnosis of intestinal ascariasis%肠道蛔虫病的钡造影X线诊断

    洪瑞锋

    2014-01-01

    Objective To study the value of X-ray diagnosis of intestinal ascariasis. Methods 2cases of intestinal ascariasis underwent barium contrast examination. Results of 2 cases of intestinal ascariasis X-ray manifestations have varying degrees of gastrointestinal adverse change, direct sign as intestinal barium insect film. Has the vital significance conclusion X-ray contrast examination in diagnosis of intestinal ascariasis, it can find the cause for direct found ascaris.%目的:探讨肠道蛔虫病的X线诊断价值。方法对2例肠道蛔虫病患者行钡造影检查。结果2例肠道蛔虫病X线表现均有不同程度胃肠功能不良改变,直接征象为肠道内钡虫影。结论 X线造影检查对肠道蛔虫病的诊断具有重要的意义,它可以为直接发现蛔虫找出病因。

  19. Comparative clinical studies of nitazoxanide, albendazole and praziquantel in the treatment of ascariasis, trichuriasis and hymenolepiasis in children from Peru.

    Juan, Jave Ortiz; Lopez Chegne, Nicholas; Gargala, Gilles; Favennec, Loic

    2002-01-01

    Three randomized clinical studies were conducted in 2000 to evaluate the efficacy of nitazoxanide paediatric suspension compared to albendazole in the treatment of ascariasis and trichuriasis and praziquantel in the treatment of hymenolepiasis in children from Cajamarca, Peru. Nitazoxanide was administered at a dose of 100 mg (age 1-3 years) or 200 mg (age 4-11 years) twice daily for 3 days, albendazole as a 400-mg single dose and praziquantel as a 25-mg/kg single dose. Post-treatment parasitological examinations were carried out on 3 faecal samples, each collected on a different day between 21 and 30 days following initiation of treatment. Nitazoxanide cured 89% (25/28), 89% (16/18) and 82% (32/39) of the cases of ascariasis, trichuriasis and hymenolepiasis respectively compared with 91% (32/35), 58% (11/19) and 96% (47/49) for the comparator drugs. Each of the drugs produced egg reduction rates in excess of 98%. There were no significant adverse events or abnormalities in haematology or clinical chemistry values or urinalysis. PMID:12055813

  20. Ascariasis as an Unexpected Cause of Acute Pancreatitis with Cholangitis: A Rare Case Report from Urban Area

    Pochamana Phisalprapa

    2013-01-01

    Full Text Available Context Ascaris lumbricoides is one of the most common parasitic infestations of human gastrointestinal tract. This parasiticinfestation might be asymptomatic and only few studies on extraintestinal ascariasis have been reported. Ascending cholangitis and acute pancreatitis as a result of the Ascaris lumbricoides migrating into the biliary system and pancreatic duct were very rare complications. Here, we presented a case report of biliary ascariasis induced acute pancreatitis with cholangitis without imaging supported in a patient coming from urban area. Case report A 33-year-old woman lives in Bangkok, urban area of Thailand. She presented with severe epigastric pain for one day. Her diagnosis was Ascaris lumbricoides induced acute pancreatitis accompanied with ascending cholangitis. The investigation results showed no eosinophilia and no ascaris eggs in stool examination. The abdominal computed tomography showed slightly common bile duct dilatation. The parasite was found during an endoscopic retrograde cholangiopancreatography performed. The cholangiography revealed a roundworm in common bile duct. The parasite was successfully removed by using an extraction balloon catheter and a snare. Microbiological examination of the parasite revealed a 22 cm long adult form of Ascaris lumbricoides. Conclusion Ascaris lumbricoides is the uncommon cause of biliary obstruction with complications. It is also a possible cause even in the patients who live in urban areas. Endoscopic removal is the treatment of choice in addition to antihelminthic medications.

  1. Intestinal obstruction in children due to Ascariasis: A tertiary health centre experience

    Mishra P

    2008-01-01

    Full Text Available Background: Ascariasis is the infestation by the largest intestinal nematode of man, a common problem in the tropics attributed to poor hygienic and low socioeconomic conditions. The aim of this research is to analyse the presentation, diagnosis and management of bowel obstruction caused by Ascaris lumbricoides, with special emphasis on the role of conservative management. Materials and Methods: This is a single centre, two consultant based 5 year retrospective study of childhood intestinal obstruction due to worms. Diagnosis in the suspected patients was based on history of passage of worms per mouth or rectum and on x-ray and ultrasonography findings. Only the patients of intestinal obstruction with documented evidence of roundworm infestation were included in the study and were followed for one year. Results: One hundred and three children with intestinal obstruction due to Ascaris lumbricoides were treated in the past five years at our centre. Abdominal pain was the most common presentation seen in 96 children followed by vomiting in 77 children. 20 children had history of vomiting worms and another 43 had history of passing worms in stool. Abdominal tenderness was present in 50 children, 48 had abdominal distension of varying degree, 50 had abdominal mass due to worm bolus, and 16 had or developed abdominal guarding or rigidity. All the children were managed as for acute intestinal obstruction along with hypertonic saline enema. The aim of management was "to starve the worm and hydrate the patient". 87 patients (84.47% responded favourably and were relieved of the obstruction by the conservative management, 16 children (15.53% had abdominal guarding or rigidity and underwent emergency exploration. Conclusion: Roundworm obstruction should be considered in the differential diagnoses of all cases of intestinal obstruction in children. Clinical history and examination along with X-ray and ultrasonography are very helpful for diagnosis of this

  2. Incidental detection of ascariasis worms on USG in a protein energy malnourished (PEM) child with abdominal pain.

    Suthar, Pokhraj Prakashchandra; Doshi, Rajkumar Prakashbhai; Mehta, Chetan; Vadera, Khyati P

    2015-01-01

    A 10-year-old child presented with dull aching periumbilical abdominal pain for 15 days. The child was not gaining weight despite a good appetite. Physical examination of the child revealed grade-I protein energy malnourishment (PEM) according to IAP (Indian Academic of Paediatrics) classification. The rest of the systemic examination was normal. Routine blood investigation revealed anaemia with eosinophilia. Abdominal ultrasonography did not show any abnormality with curvilinear transducer (3.5-5 MHz), however, linear ultrasound transducer (7.5-12 MHz) with harmonic tissue imaging showed worms in the lumen of the small intestine with curling movement on real time scanning. Stool examination for the eggs of ascariasis was positive. The patient was treated with antihelminthic drugs. Dietary modification for the PEM was advised. After 3 months of treatment, the patient improved and stool examination for Ascaris was negative on follow-up. PMID:25766437

  3. Ascariasis (For Parents)

    ... hands well and often, especially after using the bathroom and before eating. Professional Treatment Doctors usually prescribe ... or her hands often, especially after using the bathroom and before eating. Have your pets checked for ...

  4. Molecular epidemiology of ascariasis

    Betson, Martha; Halstead, Fennella; Nejsum, Peter;

      We are using molecular epidemiology techniques to study the population structure of Ascaris obtained from humans and pigs. Worms were obtained from human hosts on Zanzibar and in Uganda, Bangladesh, Guatemala and Nepal and Ascaris from pigs were collected from in Uganda, Tanzania, Denmark...

  5. Ascaris and ascariasis

    HOLLAND, CELIA

    2011-01-01

    PUBLISHED Ascaris lumbricoides and Ascaris suum are widespread parasitic nematodes of humans and pigs respectively. Recent prevalence data suggests that approximately 1.2 billion people are infected. Adult worms exhibit an overdispersed frequency distribution in their hosts and individuals harbouring heavy burdens display associated morbidity. In this review, we describe the parasite, its distribution and measures undertaken to control infection.

  6. Molecular epidemiology of ascariasis

    Betson, Martha; Nejsum, Peter; Bendall, Richard P.;

    2014-01-01

    BACKGROUND: The roundworm Ascaris lumbricoides infects 0.8 billion people worldwide, and Ascaris suum infects innumerable pigs across the globe. The extent of natural cross-transmission of Ascaris between pig and human hosts in different geographical settings is unknown, warranting investigation....... METHODS: Adult Ascaris organisms were obtained from humans and pigs in Europe, Africa, Asia, and Latin America. Barcodes were assigned to 536 parasites on the basis of sequence analysis of the mitochondrial cytochrome c oxidase I gene. Genotyping of 410 worms was also conducted using a panel of...... microsatellite markers. Phylogenetic, population genetic, and Bayesian assignment methods were used for analysis. RESULTS: There was marked genetic segregation between worms originating from human hosts and those originating from pig hosts. However, human Ascaris infections in Europe were of pig origin, and...

  7. Establishment and application of ascariasis transmission mathematical models in China%我国蛔虫病传播数学模型的建立与应用

    王骏; 陈颖丹; 刘伦皓; 李华忠; 汤林华

    2011-01-01

    目的 建立我国蛔虫病传播数学模型并用于现场预测.方法 选择四川翠屏、江西进贤和湖南岳阳3个调查点,通过现场调查获取基线、服药后1月和1年后人群蛔虫感染率及平均虫负荷,构建蛔虫种群动力学、分布及感染率等传播数学模型.由现场数据获得模型参数,代入模型后预测1年后的感染水平,与实际调查数据比较,针对与药物驱虫措施相关的因素进行敏感性分析.结果 翠屏、进贤、岳阳3个调查点蛔虫基线感染率分别为28.79%、20.35%和20.72%,平均虫负荷分别为1.32、0.65和0.48,药物驱虫后1年感染率分别为30.10%、7.51%和0.94%,平均虫负荷分别为1.04、0.56和0.34.服药1年后感染率和平均虫负荷均在实际观察值的95%可信区间内.敏感性分析结果显示服药覆盖率和治疗频次是影响疾病收益(平均虫负荷、感染率)的重要因素.结论 本研究建立的蛔虫病传播数学模型较好地拟合了现场数据,可为制定蛔虫病控制规范和优化防治策略提供理论依据.%Objective To establish ascariasis transmission mathematical models and apply them to predict field status. Methods Cuiping District in Sichuan Province, Jinxian County in Jiangxi Province and Yueyang County in Hunan Province were selected as the investigation sites. The Ascaris lumbricoides infection rates and mean worm burdens of baseline, 1 month and 1 year later after deworming were acquired by field surveys. The transmission models on population dynamics, distribution and infection rate were developed. The model parameters obtained through the field data were substituted into models to predict the infection level one year after deworming. The predicted values were compared with the actual survey data, and the sensitivity analysis was performed to analyze factors related to the chemotherapy measures. Results The infection rates of Cuiping, Jinxian and Yueyang at baseline were 28.79%, 20

  8. 高频超声在诊断小儿肠道蛔虫症中的应用价值%Value of high frequency ultrasound in the diagnosis of intestial ascariasis in children.

    王东林; 符少清; 刘秉彦

    2011-01-01

    Objective To investigate the value of applying high frequency ultrasound in the diagnosis of intestinal ascariasis in children. Methods The clinical and sonographic data of 27 children with abdominal pain were analyzed retrospectively. Results One to several ascarides were found in the intestinal of the 27 patients by sonography. After treatment by helminthicide, the ascarides were found to be either discharged or unobserved by sonography.Conclusion High frequency ultrasound has high clinical value in the diagnosis of intestinal ascariasis in children,which can be the optimum choice for the imaging examination of the disease.%目的 探讨高频超声在诊断小儿肠道蛔虫症中的价值.方法 回顾性分析27例腹痛患儿的临床及超声影像资料.结果 27例患儿肠腔内均可见一至数条蛔虫图像,经驱虫治疗后排出蛔虫或复查超声肠腔内未见蛔虫图像.结论 高频超声在诊断小儿肠道蛔虫症中有很高的临床价值,可作为该病首选的影像学检查方法.

  9. Asma e ascaridíase em crianças de 2 a 10 anos de um bairro de periferia Asthma and ascariasis in children aged two to ten living in a low income suburb

    Maria Teresa Nascimento Silva

    2003-06-01

    Full Text Available OBJETIVO: avaliar a associação entre asma e ascaridíase em crianças do bairro Pedregal, da cidade de Campina Grande (Paraíba, onde são baixos os indicadores de desenvolvimento humano. MATERIAL E MÉTODO: foi aplicado o questionário padrão do International Study of Asthma and Allergies in Childhood (ISAAC, em 1.095 crianças, mas apenas 742 o responderam e entregaram a amostra fecal para realização do exame parasitológico. A faixa etária das 742 crianças incluídas no estudo transversal foi de 2 a 10 anos de idade. A associação entre asma e ascaridíase foi estudada pelo índice Kappa. As análises das variáveis demográficas e clínicas, comparando os dois grupos, foram realizadas pelo teste do qui-quadrado (chi² ou o teste t de Student para os dados quantitativos (contínuos. RESULTADOS: nas 742 crianças, as proporções dos sexos foram semelhantes: 51,9% (n = 385 do masculino e 48,1% (n = 357 do feminino. Nessas crianças, a prevalência de asma foi de 59,7% (n = 443 e da ascaridíase de 56,3% (n = 418, sendo semelhante (chi² = 0,27; p > 0,60 a freqüência de asma no grupo portador de ascaridíase (60,5% ou sem essa helmintíase (58,6%. CONCLUSÃO: apesar da elevada freqüência dos agravos estudados, não há aparente associação entre asma e ascaridíase na população estudada.OBJECTIVE: to assess the relation between children with asthma and ascariasis in the low income neighborhood of Pedregal, in Campina Grande (Paraíba, Brazil. MATERIAL AND METHOD: the International Study of Asthma and Allergies in Childhood (ISSAC standard questionnaire was distributed to 1,095 children but only 742 of them answered it and provided stool samples for parasite examination. The cross-sectional study included those 742 children, whose age ranged from 2 to 10 years. The association between asthma and ascariasis was studied through Kappa rating. Demographic and clinic variants comparing the two groups were analyzed by chi-square test

  10. HEPATOBILIARY ASCARIASIS COMPLICATED BY PANCREATITIS.

    Azhar, Muhammad; Sheikh, Ali Sibtain Farooq; Khan, Asim; Mustafa, Saqib; Shah, Imran Ali; Hameed, Bilal

    2015-01-01

    Ascaris lumbricoides is the commonest organism causing soil-transmitted helminth infection. It is particularly common in poor sanitary conditions. Nevertheless, involvement of the gallbladder by Ascaris is a rare entity. A lady presented to us with long-standing history of vague abdominal symptoms suggesting dyspepsia. Ultrasound showed a tube like structure invading the biliary channels. Serum amylase was elevated and the patient was managed conservatively, as for acute pancreatitis. She improved clinically, but subsequent imaging with magnetic resonance cholangiopancreatography revealed worm in the gallbladder. Laparoscopic cholecystectomy was done and Ascaris lumbricoides was removed. Ascaris infestation is an important differential diagnosis of patients with upper abdominal symptoms and screening with stool examination and ultrasound is warranted in high-risk population. PMID:26411145

  11. Gallbladder Ascariasis : A Rare Case

    Yıldırım, İsmail Okan; Aktaş, Ayşe

    2014-01-01

    A 21 year-old female patient admitted to the emergency room complaining of right upper quadrant pain that had lasted for 6 months. The abdominal USG revealed hydropic gallbladder (89x40 mm) and the wall thickness was in normal limits. There was a linear undulant hyperechogenic membranous structure that was located along the bladder lumen with hyperechogenic and solid nodulations in the lumen. MRCP revealed undulant appearance and hypointensed curvilinear appearance with T2A in gallbladder. Th...

  12. Hepatobiliary alterations in massive biliary ascariasis: histopathological aspects of an autopsy case Lesões hepatobiliares em ascaridíase biliar maciça: aspectos histopatológicos em um caso de autópsia

    Luiz Carlos da Costa Gayotto

    1990-04-01

    Full Text Available Hepatobiliary alterations found in an autopsy case of massive Biliary Ascariasis, are reported on histological grounds. Severe cholangitis was the main finding, but other changes were also detected, such as pyloric and intestinal metaplasia, hyperplasia of the epithelial lining, with intraductal papillomas and adenomatous proliferation. Remnants of the worm were observed tightly adhered to the epithelium, forming microscopic intrahepatic calculi. Mucopolysaccharides, especially acid, showed to be strongly positive on the luminal border, and in proliferated glands around the ducts. The authors discuss the similarity between such findings and Oriental Cholangiohepatitis, and suggest that inflammation and the presence of the parasitic remnants are responsible for the hyperplastic and metaplastic changes, similarly with what occurs in chlonorchiasis, fascioliasis and schistosomiasis.Os autores apresentam os aspectos histopatológicos encontrados no fígado de um caso de autópsia de Ascaridíase Biliar maciça. A intensa colangite foi o aspecto predominante, mas outras lesões também foram encontradas, tais como metaplasia pilórica e intestinal, hiperplasia epitelial com papilomas intraductais, e por vezes padrão adenomatoso. Restos do helminto foram encontrados fortemente aderidos ao epitélio, sendo intensa a positividade de mucopolissacárides, principalmente ácidos, na borda luminal do epitélio ductal e em glândulas proliferadas ao redor dos ductos. Os autores discutem a semelhança da Ascaridíase Biliar com a Colangio Hepatite Oriental, e sugerem que o processo inflamatório e a presença de restos do verme são responsáveis pelas alterações hiperplásicas e metaplásicas, analogamente ao que ocorre na clonorquíase, fasciolíase e esquistossomose.

  13. Biliary ascariasis on magnetic resonance cholangiopancreatography

    Mohammad A Hashmi

    2009-01-01

    Full Text Available A 17-year-old girl presented with features of biliary obstruction. Magnetic resonance cholangi-pancreatography revealed typical linear signals in common bile duct, which appears like Ascaris lumbricoides. The diagnosis was confirmed by endoscopic removal of the worm.

  14. Asymptomatic intraperitoneal ascariasis: Importance of diagnostic laparoscopy

    Santhosh Anand; Sharma, Aditya P; Sandeep Aggarwal; Devajit Nath; Sandeep Mathur

    2014-01-01

    Migration of Ascaris from intestine into peritoneal cavity is rare and usually presents as acute abdomen. We report a case of 41-year-old male who was admitted for laparoscopic mesh rectopexy for rectal prolapse. During the initial laparoscopy, purulent fluid was seen in pelvis. A complete diagnostic laparoscopy was done. An omental nodule was found, which was excised and extracted in a bag. On histopathology, the omental nodule revealed gravid Ascaris lumbricoides.

  15. Biliary Ascariasis on Magnetic Resonance Cholangiopancreatography

    Hashmi, Mohammad A; Jevan K De

    2009-01-01

    A 17-year-old girl presented with features of biliary obstruction. Magnetic resonance cholangi-pancreatography revealed typical linear signals in common bile duct, which appears like Ascaris lumbricoides. The diagnosis was confirmed by endoscopic removal of the worm.

  16. Pulmonary ascariasis in a polytraumatized patient

    The parasitism of the lung for Ascaris is a rare entity, associated with factors related to age, environmental conditions and hygiene. It is usually asymptomatic, but when the larva enters in the cycle lung can become symptomatic. Characterized by fever, dyspnoea, chest pain, cough with hemoptysis, eosinophilia and alveolar infiltrates on chest radiograph. His diagnosis is the isolation of the parasite. We describe a case of a patient polytraumatized during her hospitalization present alveolar infiltrates, associated with eosinophilia and document of ascaris larva in the lung.

  17. Ascariasis Is a Zoonosis in Denmark

    Nejsum, Peter; Parker, E. Davis; Frydenberg, Jane; Roepstorff, Allan; Boes, Jaap; Haque, Rashidul; Astrup, Ingrid; Prag, Jørgen; Skov Sørensen, Uffe B.

    2005-01-01

    A preliminary epidemiological survey indicated an association between Ascaris infections in Danish patients and contact with pigs or pig manure. In the present study, we compared Ascaris worms collected from humans and Ascaris worms collected from pigs by amplified fragment length polymorphism (AFLP) analysis, a technique for whole-genome fingerprinting, and by PCR-linked restricted fragment length polymorphism (PCR-RFLP) analysis of the internal transcribed spacer region of nuclear rDNA. The...

  18. Ascariasis er en zoonose i Danmark- sekundærpublikation

    Nejsum, Peter; Parker, E. Davis; Frydenberg, Jane;

    2006-01-01

    Forekomsten af humane spolorminfektioner (askariose) er tidligere forklaret ved, at smitten enten er erhvervet under udlandsrejser eller ved indtagelse af uforarbejdede levnedsmidler importeret fra lande, hvor sygdommen er almindeligt forekommende. Epidemiologiske undersøgelser udført i Viborg Am...

  19. Respiratory Failure Associated with Ascariasis in a Patient with Immunodeficiency.

    Aleksandra, Lanocha; Barbara, Zdziarska; Natalia, Lanocha-Arendarczyk; Danuta, Kosik-Bogacka; Renata, Guzicka-Kazimierczak; Ewa, Marzec-Lewenstein

    2016-01-01

    In industrialized countries, risk groups for parasitic diseases include travelers, recent immigrants, and patients with immunodeficiency following chemotherapy and radiotherapy and AIDS. A 66-year-old Polish male was admitted in December 2012 to the Department of Haematology in a fairly good general condition. On the basis of cytological, cytochemical, immunophenotypic, and cytogenetic analysis of bone marrow, the patient was diagnosed with acute myeloblastic leukemia. On the 7th day of hospitalization in the Department of Haematology, patient was moved to the Intensive Care Unit (ICU) due to acute respiratory and circulatory failure. In March 2013, 3 months after the onset of respiratory failures, a mature form of Ascaris spp. appeared in the patient's mouth. This report highlights the importance of considering an Ascaris infection in patients with low immunity presenting no eosinophilia but pulmonary failure in the central countries of Europe. PMID:27313919

  20. Intestinal ascariasis at pediatric emergency room in a developed country

    Umetsu, Shuichiro; Sogo, Tsuyoshi; Iwasawa, Kentaro; Kondo, Takeo; Tsunoda, Tomoyuki; Oikawa-Kawamoto, Manari; Komatsu, Haruki; Inui, Ayano; Fujisawa, Tomoo

    2014-01-01

    Ascaris lumbricoides infection is rare among children in developed countries. Although large numbers of adult Ascaris in the small intestine can cause various abdominal symptoms, this infection remains asymptomatic until the number of worms in the intestine considerably increases in most cases. Ascaris causing bilious vomiting suggesting ileus is rare, especially in developed countries. A 6-year-old boy who lived in Japan, presented with abdominal colic, bilious vomiting at the pediatric emer...

  1. Evolution of ascariasis in humans and pigs: a multi-disciplinary approach

    Loreille Odile; Bouchet Françoise

    2003-01-01

    The nematode parasite Ascaris lumbricoides infects the digestive tracts of over 1.4 billion people worldwide, and its sister species, Ascaris suum, has infected a countless number of domesticated and feral pigs. It is generally thought that the putative ancestor to these worms infected either humans or pigs, but with the advent of domestication, they had ample opportunity to jump to a new host and subsequently specialize and evolve into a new species. While nuclear DNA markers decisively sepa...

  2. Epidemiological Study of Ascariasis in Hamadan City , West of Iran, 2001

    M. Fallah; M.H. Azimian; M. Nabiee; M Hojati

    2004-01-01

    Ascaris lumbricoides is the most common intestinal parasite in the world. Various studies has indicated the high prevalence of this parasite in Iran, specially in the west parts of Iran. The epidemiological study of intestinal parasitic infection is prerequisite for planning of control programs. The Hamadan province is one of the most tourist attraction regions of Iran and providing a safe environment for travelers is the main aim of regional authorities. A mass chemotherapy...

  3. Co-existent Ascariasis and Multiloculated Tuberculous Pleurisy Treated with Intrapleural Streptokinase.

    Mahmud, Talha; Naeem, Omer Muhammad

    2015-10-01

    This case describes a young male with pleuro-pulmonary tuberculosis having one-week history of fever and hemoptysis along with a multiloculated right sided exudative lymphocytic pleural effusion. His pulmonary diagnostic confusion was due to passage of adult Ascaris lumbricoides per orally but that was found to be of intestinal origin. Pleural tissue histopathology revealed necrotizing granulomatous inflammation and right upper lobe bronchial washings were positive for acid fast bacilli. His multiloculated pleural effusion was successfully resolved with intrapleural streptokinase injections via a 10 French pleural catheter. Treatment with class-I anti-tuberculous drugs led to complete clearance of remaining pleuro-pulmonary shadowing. PMID:26522189

  4. Evidence for in utero sensitization to Ascaris lumbricoides in newborns of mothers with ascariasis

    Guadalupe, Irene; Mitre, Edward; Benitez, Susana; Martha E Chico; Nutman, Thomas B.; Cooper, Philip J.

    2009-01-01

    Human infections with Ascaris lumbricoides may have important effects on allergy and susceptibility to infectious diseases that start in early life. To investigate if sensitization to Ascaris occurs in utero, we measured IFN-γ and IL-4 responses in Ascaris antigen-stimulated cord blood of newborns of infected and non-infected mothers using flow cytometry. There was evidence of elevated frequencies of IFN-γ and IL-4-expressing CD4+ T cells in newborns of infected mothers compared to those of n...

  5. Ascaridíase hepatobiliar complicada por pneumonia lipoídica Hepatobiliary ascariasis complicated by lipoid pneumonia

    Lisieux Eyer de Jesus; Selma Maria A. Sias; Alan Araújo Vieira; Iara Teixeira Gonçalves; Rafael Del Castillo Villalba; Marcia Regina F. André

    2008-01-01

    OBJETIVO: Apresentar um caso de ascaridíase hepatobiliar complicado por pneumonia lipoídica e discutir as implicações anestésicas envolvidas. DESCRIÇÃO DO CASO: Menina de dois anos de idade com ascaridíase hepatobiliar complicada por pneumonia lipoídica por aspiração e desnutrição grave, advinda de família em condições sociais precárias em zona rural, com quatro irmãos. Foi tratada com sucesso por uma combinação de lavados broncopulmonares sucessivos e cirurgia. COMENTÁRIOS: Ascaridíase bilia...

  6. Molecular paleoparasitological diagnosis of Ascaris sp. from coprolites: new scenery of ascariasis in pre-Colombian South America times

    Daniela Leles

    2008-02-01

    Full Text Available Paleoparasitological studies using microscopy showed that Ascarisand Trichuris trichiura are the human intestinal parasites most found in archaeological sites. However, in pre-Columbian South American archaeological sites, Ascaris is rare. In this work we standardized a molecular methodology for Ascaris diagnosis directly from ancient DNA retrieved from coprolites. Using cythochrome b gene (142 bp target, ancient DNA sequences were retrieved from South American samples, negative by microscopy. Moreover, the methodology applied was sensitive enough to detect ancient DNA extracted from 30 Ascaris eggs from an European coprolite. These results revealed a new scenery for the paleodistribution of Ascaris in South America.

  7. A CLINICAL STUDY OF THE USE OF PYRVINIUM PAMOATE WITH PIPERAZINE (VANPAR® IN THE TREATMENT OF OXYURIASIS AND ASCARIASIS

    M.A. Barzgar

    1974-07-01

    Full Text Available In this study oxyuris and ascaris infections alone or in combination were treated with Vanapar a combination of Pyrvinium Pamoate and Piperazine administered in two successive daily doses. This resulted in a 100% cure rate of oxyuriasis as well as a substantial reduction in ova count for ascaris, amounting to 97% success rate in achieving ova count reduction. Vanapar was highly effective for the management of pinworm and roundworm infections in this study. The drug was well tolerated with only seven patients (8.8% displaying drug-attributable adverse experiences.

  8. Molecular paleoparasitological diagnosis of Ascaris sp. from coprolites: new scenery of ascariasis in pre-Colombian South America times

    Daniela Leles; Adauto Araújo; Luiz Fernando Ferreira; Ana Carolina Paulo Vicente; Alena Mayo Iñiguez

    2008-01-01

    Paleoparasitological studies using microscopy showed that Ascarisand Trichuris trichiura are the human intestinal parasites most found in archaeological sites. However, in pre-Columbian South American archaeological sites, Ascaris is rare. In this work we standardized a molecular methodology for Ascaris diagnosis directly from ancient DNA retrieved from coprolites. Using cythochrome b gene (142 bp) target, ancient DNA sequences were retrieved from South American samples, negative by microscop...

  9. Molecular epidemiology of ascariasis: a global perspective on the transmission dynamics of Ascaris in people and pigs.

    Betson, M.; Nejsum, P; Bendall, RP; Deb, RM; Stothard, JR

    2014-01-01

    Background.  The roundworm Ascaris lumbricoides infects 0.8 billion people worldwide, and Ascaris suum infects innumerable pigs across the globe. The extent of natural cross-transmission of Ascaris between pig and human hosts in different geographical settings is unknown, warranting investigation. Methods.  Adult Ascaris organisms were obtained from humans and pigs in Europe, Africa, Asia, and Latin America. Barcodes were assigned to 536 parasites on the basis of sequence analysis of the mito...

  10. Possible Approach for Serodiagnosis of Ascariasis by Evaluation of Immunoglobulin G4 Response Using Ascaris lumbricoides Somatic Antigen

    Bhattacharyya, Tanusree; Santra, Amal; Majumder, Debendra N. Guha; Chatterjee, Bishnu P.

    2001-01-01

    Somatic antigen of Ascaris lumbricoides was purified to homogeneity (molecular mass, 34 kDa) by ammonium sulfate fractionation and successive chromatographic procedures, namely, gel permeation, ion exchange, and high-performance gel permeation liquid chromatographies. The antigen showed strong binding with immunoglobulin G (IgG) in Ascaris-infested patients and was cross-reactive with IgE and IgG in patients infested with other nematodes. It reacted specifically with IgG4 (P < 0.001) in 63 As...

  11. Endoscopic retrograde cholangio-pancreatographic diagnosis and extraction of massive biliary ascariasis presented with acute pancreatitis: a case report.

    Saowaros, V

    1999-05-01

    This paper reports the case of a young female Thai patient who presented with periodic severe abdominal pains which proved to be acute pancreatitis. Conventional investigations and treatments failed to prove and improve her condition. ERCP was done on the twelfth day after admission. 3 caudal ends of living round worms were noted protruding from the papillary orifice during endoscopy. Cholangiography revealed impacted multiple round worms in the common bile duct and both intrahepatic ducts. Endoscopic extraction of the worms was done by using dormia basket and removed with endoscope. Repeated procedure was done 21 times in two and a half hours, obtaining 26 live, mature Ascaris lumbricoides varying from 13 to 24 cm in length. Repeated cholangiogram confirmed complete removal of the worms. The patient was relieved from abdominal pain immediately after the procedure, and given oral albendazole 400 mg daily for 7 days. She was discharged asymptomatic 8 days after Ascaris removal. PMID:10443103

  12. Disease: H01090 [KEGG MEDICUS

    Full Text Available H01090 Ascariasis Ascariasis is an commonly documented parasitic infection in sub-Saharan Africa ... ID:6377443 (description) Arfaa F Selective primary health ... care: strategies for control of disease in the dev ...

  13. Ascaridíase biliar complicada: espectro de problemas e táticas cirúrgicas Biliary ascariasis: spectrum of surgical problems and tactics

    Lisieux Eyer de Jesus; Ricardo Pecoraro Raposo; Alexandre Guazelli

    2004-01-01

    OBJETIVO: Discutir as variantes clínicas e táticas para tratamento cirúrgico da ascaridíase biliar complicada. MÉTODO: Trabalho retrospectivo de pacientes operados por complicações de ascaridíase biliar num período de cinco anos. RESULTADOS: São descritos quatro casos de ascaridíase biliar complicada em crianças (três pré escolares e um escolar), expressos através de pseudocisto pancreático, icterícia obstrutiva, colangite e múltiplos abscessos hepáticos, todos tratados cirurgicamente. Descre...

  14. Surgical complications of Ascaris lumbricoides in children

    Ramareddy, Raghu S.; Anand Alladi; O S Siddapa; Deepti, V; Tanveer Akthar; B Mamata

    2012-01-01

    Aim : To report the surgical complications of Ascaris lumbricoides infestation in children. Materials and Methods : This is a retrospective study and cases of intestinal ascariasis managed conservatively were excluded. Results : Sixteen children presented with Ascariasis sequelae, which included ileal volvulus (n=5), perforations (n=4), intussusception (n=1), biliary ascariasis (n-1) and impacted multiple worm boluses (n=5). Plain abdominal radiographs showed pneumoperitoneum (3), cigar bundl...

  15. АСКАРИДОЗ: ПРОЯВЛЕНИЯ ЭПИДЕМИЧЕСКОГО ПРОЦЕССА И ПРОФИЛАКТИКА В ГОМЕЛЬСКОЙ ОБЛАСТИ

    Н.В. Нараленкова; Т.Г. Мурашкевич

    2014-01-01

    Ascariasis morbidity in Gomel region in 2004 – 2013 shows a tendency to decrease. In age distribution children and up to 17 years old teenagers prevail. Both villagers and urbanites are reported to be sick with ascariasis. Though, high rates of environment contamination with ascariasis pathogens indicates instability of epidemic process. Informational and educational activities within population demand significant intensification. Measures for protection environment from helminthes pathogens ...

  16. Parasitic diseases of lungs

    Roentgenologic semiotics of the main parasitic diseases of lungs is described: echinococcosis, paragonimiasis, cysticercosis, toxoplasmosis, ascariasis, amebiosis and some rarely met parasitic diseases

  17. Asma e ascaridíase em crianças de 2 a 10 anos de um bairro de periferia Asthma and ascariasis in children aged two to ten living in a low income suburb

    Maria Teresa Nascimento Silva; Jacy Andrade; José Tavares-Neto

    2003-01-01

    OBJETIVO: avaliar a associação entre asma e ascaridíase em crianças do bairro Pedregal, da cidade de Campina Grande (Paraíba), onde são baixos os indicadores de desenvolvimento humano. MATERIAL E MÉTODO: foi aplicado o questionário padrão do International Study of Asthma and Allergies in Childhood (ISAAC), em 1.095 crianças, mas apenas 742 o responderam e entregaram a amostra fecal para realização do exame parasitológico. A faixa etária das 742 crianças incluídas no estudo transversal foi de ...

  18. Prevention and treatment of ascariasis in demonstration plots of integrated control from 2006 to 2009%我国寄生虫病综合防治示范区蛔虫病3年防治效果

    诸廷俊; 陈颖丹; 许隆祺

    2011-01-01

    目的 了解寄生虫病综合防治示范区蛔虫感染现状,探索蛔虫病防治措施.方法 在示范区实施健康教育、药物驱虫和改水改厕等综合干预措施,观察措施实施前后居民蛔虫感染率的变化.结果 3年中示范区累计驱虫620余万人次,服药覆盖率达81.65%,居民蛔虫感染率由2006年的17.81%降至2009年的2.52%.居民卫生知识知晓率由45.11%提高到95.99%,改水受益率达84.09%,无害化厕所覆盖率为50.30%.结论 通过3年综合防治,示范区居民蛔虫感染率下降明显.%Objective To understand the situation of Ascaris lumbricoides infection in the demonstration plots and evaluate the effect of integrated intervention measures. Methods The integrated intervention measures included health education, mass chemotherapy, safe water and sanitary toilets. The changes of infection rates of Ascaris lumbricoides in residents were observed before and after the intervention. Results With the 3-year' s intervention, the Ascaris lumbricoides infection rates decreased from 17.81% to 2.52%, the rate of mass chemotherapy was 81.65%, which covered more than 6.2 million person-time, the awareness rates of parasitic disease control knowledge among the residents raised from 45.11% to 95.99%, and 84.09% of local people were supplied with safe water and 50.30% of families had sanitary toilets. Conclusion The Ascaris lumbricoides infection rate decreases dramatically through the 3-year s intervention.

  19. Successful Elimination of Ascaris lumbricoides from the Gallbladder by Conservative Medical Therapy

    Misra, Manish Kumar; Singh, Sarabjeet; Bhagat, Tripta Sethi

    2012-01-01

    Migration of Ascaris lumbricoides into the gallbladder is rare, unlike ascariasis of the bile duct and when it does occur, treatment is generally by endoscopic or surgical extraction. We describe a case of the successful treatment of gallbladder ascariasis with conservative therapy.

  20. An unusual case of fever and abdominal pain

    Arundhati G Diwan

    2012-01-01

    Full Text Available Ascariasis is one of the commonest parasitic infestations in tropical countries. Main symptoms are pain in abdomen, weight loss, diarrhea and passage of worms in stool. If acute, it may present as intestinal obstruction, perforation, cholangitis, appendicitis and pancreatitis. The incidence of hepato-biliary ascariasis is probably underestimated. We report a case which presented to us with fever, abdominal pain and weight loss of a month′s duration, mimicking abdominal tuberculosis. On investigations, patient was found to have ascariasis of gall bladder, terminal ileum, caecum and appendix, causing simultaneous inflammation of all these structures.

  1. The Impact of Cultural Behaviours, Local Beliefs, and Practices on Emerging Parasitic Diseases in Tropical Africa

    Onwuliri, Celestine O. E.; Anosike, Jude C.; Oguoma, Chibuzor; Onwuliri, Viola A.; Nwoke, Betram E. B.; Dozie, Ikechukwu, N. S.; Iwuala, Moses O. E.

    2005-01-01

    The scourge of emerging parasitic diseases (e.g., urinary schistosomiasis, ascariasis, malaria, chagas disease, leishmaniasis, trachoma, trichiuriasis, taeniasis, dracunculiasis, sleeping sickness, filariasis) causes tremendous pain, suffering, and eventually death in tropical African communities. Patterns of transmission of these emerging…

  2. Simple pulmonary eosinophilia

    ... Pneumocystis jirovecii A parasite, including the roundworms Ascariasis lumbricoides , or Necator americanus , or the hookworm Ancylostoma duodenale ... contents ( gastric lavage ) may show signs of the Ascaris worm or another parasite. Treatment If you are ...

  3. Potensi Serbuk Daun Kelor (Moringa oleifera) Sebagai Anthelmintik Terhadap Infeksi Ascaris suum dan Feed Supplement pada Babi

    Muhammad Ulqiya Syukron; I Made Damriyasa; Nyoman Adi Suratma

    2015-01-01

    Pig ascariasis is an intestinal parasitic disease caused by Ascaris suum. The economic losses in pig ascariasis are caused by a bad feed conversion ratio (FCR) and rejection of some organs after animal slaughtering. An anthelmintic utilization and farm management improvement are the common prevention action, however, recently the utilization of herbs as an athelmintic has been developed, one of them is Moringa oleifera leaves. Moringa oleifera leaves are also a potential for a sources of ani...

  4. ASCARIDIA COLUMBAE IN COLUMBIA LIVIA DOMESTICA

    B. Bizhga; E. Sotiri; A. Bocari; D. Kolleshi

    2011-01-01

    Ascaridia columbae is the cause of ascariasis in pigeons. The object of this study carried out in Tirana and Lushnja was the presence of ascariasis, identification and parasite load in pigeons (Columbia livia domestica). 5 dead pigeons were examined, 8 others were sacrificed and fecal samples were examined repeatedly, taken from 2 coops with pigeons, 1 for each area out of a total of 192 poultry. Ascaridia columbae was frequently evidenced in the pigeons of our country. Its prevalence results...

  5. An unusual case of fever and abdominal pain

    Arundhati G Diwan; Varsha S Dabadghao; T A Najeeb; Priti Dave

    2012-01-01

    Ascariasis is one of the commonest parasitic infestations in tropical countries. Main symptoms are pain in abdomen, weight loss, diarrhea and passage of worms in stool. If acute, it may present as intestinal obstruction, perforation, cholangitis, appendicitis and pancreatitis. The incidence of hepato-biliary ascariasis is probably underestimated. We report a case which presented to us with fever, abdominal pain and weight loss of a month′s duration, mimicking abdominal tuberculosis. On invest...

  6. The IgE response to Ascaris molecular components is associated with clinical indicators of asthma severity

    Buendía, Emiro; Zakzuk, Josefina; Mercado, Dilia; Alvarez, Alvaro; Caraballo, Luis

    2015-01-01

    Background Asthma is a common chronic disease worldwide and Ascaris lumbricoides infection (ascariasis) is frequent in tropical regions. However, the effect of ascariasis on asthma severity has not been sufficiently explored. We sought to evaluate the influence of the IgE immune response to Ascaris extract and purified house dust mites (HDM) and Ascaris allergens on indicators of asthma severity in patients living in the tropics. Methods Asthmatic patients from Cartagena, Colombia were recrui...

  7. Community Rates of IgG4 Antibodies to Ascaris Haemoglobin Reflect Changes in Community Egg Loads Following Mass Drug Administration

    Vlaminck, Johnny; Supali, Taniawati; Geldhof, Peter; Cornelis H Hokke; Fischer, Peter U.; Weil, Gary J

    2016-01-01

    Background Conventional diagnostic methods for human ascariasis are based on the detection of Ascaris lumbricoides eggs in stool samples. However, studies of ascariasis in pigs have shown that the prevalence and the number of eggs detected in the stool do not correlate well with exposure of the herd to the parasite. On the other hand, an ELISA test measuring antibodies to Ascaris suum haemoglobin (AsHb) has been shown to be useful for estimating transmission intensity on pig farms. In this st...

  8. Ascaris lumbricoides: To Expect the Unexpected during a Routine Colonoscopy

    Kalyan Kanneganti; Makker, Jasbir S.; Prospere Remy

    2013-01-01

    Ascaris lumbricoides is a common nematode infecting humans worldwide with increased prevalence in tropical and subtropical areas of less developed countries. Recently, it has been estimated that over one billion individuals are infected with ascariasis worldwide with 7% in USA. Although most of these cases are due to increasing immigration and travel outside America it is worth recognizing that prevalence of ascariasis is high in southeastern parts of USA due to their temperate climate. Infec...

  9. Ascariasis in the subdistrict of Cavacos, municipality of Alterosa (MG), Brazil: effect of mass treatment with albendazole on the intensity of infection Ascaridiose no subdistrito de Cavacos, município de Alterosa (MG), Brasil: efeito do tratamento em massa com albendazol sobre a intensidade de infecção

    Marcos T Machado; Telma M. S. Machado; Roberto M Yoshikae; Ana Lúcia A Schmidt; Rita de Cássia A Faria; Maria A Paschoalotti; Rita de Cássia B Barata; Pedro P. Chieffi

    1996-01-01

    The clinical and epidemiologic aspects of infection with Ascaris lumbricoides were studied in a random stratified sample of the population of the subdistrict of Cavacos, municipality of Alterosa (Minas Gerais, Brazil). The effect of mass treatment with a single dose of albendazole on the prevalence and intensity of infection was also studied six months later in the same population. During the first phase of the study, a questionnaire was applied to 248 individuals to obtain information about ...

  10. Ascariasis in the subdistrict of Cavacos, municipality of Alterosa (MG, Brazil: effect of mass treatment with albendazole on the intensity of infection Ascaridiose no subdistrito de Cavacos, município de Alterosa (MG, Brasil: efeito do tratamento em massa com albendazol sobre a intensidade de infecção

    Marcos T Machado

    1996-08-01

    Full Text Available The clinical and epidemiologic aspects of infection with Ascaris lumbricoides were studied in a random stratified sample of the population of the subdistrict of Cavacos, municipality of Alterosa (Minas Gerais, Brazil. The effect of mass treatment with a single dose of albendazole on the prevalence and intensity of infection was also studied six months later in the same population. During the first phase of the study, a questionnaire was applied to 248 individuals to obtain information about the socioeconomic, sanitary and clinical conditions of the population surveyed. A total of 230 fecal samples were also examined by the Kato-Katz technique in order to determine the intensity of A. lumbricoides infection. Two hundred and two individuals were simultaneously submitted to blood counts and 70 children aged 12 years or less were evaluated for nutritional status. The presence of A. lumbricoides and other helminth eggs was also determined in 22 soil samples collected in the urban zone of Cavacos. Infection with enteroparasitic helminths was detected in 29.1% of the sample, with a predominance of A. lumbricoides (23.9%. Parasitism and/or intensity of A. lumbricoides infection were significantly correlated with age range (15 years or less, social class, sanitary and living conditions (water, sewage and domiciliary area per person, and presence of abdominal pain. However, these parameters were not correlated with nutritional status or hematocrit levels. During the second phase of the study, a slight but not statistically significant decrease in the prevalence of A. lumbricoides infection was detected after treatment with albendazole. However, an important and significant reduction in the amount of A. lumbricoides eggs eliminated through the feces was detected, indicating that the intensity of A. lumbricoides infection was lower in all the age ranges of the Cavacos population, especially among younger individuals, even six months after administration of the anthelminthic agent.Em amostra aleatória E estratificada da população do subdistrito de Cavacos, no município de Alterosa (Minas Gerais, Brasil estudaram-se os aspectos clínicos e epidemiológicos da infecção por Ascaris lumbricoides. Avaliou-se, também, na mesma amostra, seis meses mais tarde, o efeito do tratamento em massa com albendazol sobre a prevalência e intensidade de infecção por esse nematóide. Na primeira fase do estudo, realizou-se inquérito em 248 indivíduos, utilizando questionário que investigava aspectos relativos a condições socioeconômicas, sanitárias e clínicas. Foram, também, examinadas 230 amostras de fezes pela técnica de Kato-Katz, visando determinação da prevalência e intensidade de infecção por A. lumbricoides. Ao mesmo tempo, 202 indivíduos foram submetidos a micro-hematócrito e em 70 crianças com idade menor ou igual a 12 anos efetuou-se avaliação do estado nutricional. Determinou-se, ainda, a presença de ovos de A. lumbricoides e outros helmintos em 22 amostras de solo colhidas na zona urbana de Cavacos. Os resultados mostraram ocorrência de infecção por helmintos enteroparasitas em 29,1% da amostra examinada, com predomínio de A. lumbricoides (23,9%. Observou-se relação significativa do parasitismo e/ou intensidade de infecção por A. lumbricoides com faixa etária (idade menor ou igual a 15 anos, classe social, condições sanitárias e de habitação (água, esgoto e área domiciliar por pessoa e presença de dor abdominal. Não se notou, entretanto, associação desses parâmetros com o estado nutricional e níveis de hematócrito. Na segunda fase do estudo, encontrou-se discreta diminuição na prevalência de infecção por A. lumbricoides, sem significância do ponto de vista estatístico, seis meses após tratamento em massa com albendazol. Notou-se, entretanto, importante e significativa redução na quantidade de ovos de A. lumbricoides eliminados pelas fezes, indicando que mesmo seis meses após administração do anti-helmíntico é menor a intensidade de infecção por A. lumbricoides em todas as faixas etárias da população de Cavacos, especialmente entre os mais jovens.

  11. Encountering Meckel's diverticulum in emergency surgery for ascaridial intestinal obstruction

    Amin Abid

    2010-06-01

    Full Text Available Abstract Background Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract. In children with intestinal ascariasis, the diverticulum remains asymptomatic or rarely the Ascaris lumbricoides may lead to its complications in the presence of massive intestinal roundworm load. Given that preoperative diagnosis is seldom carried out, when Meckel's diverticulum is found at laparotomy for obstructive intestinal complications of roundworm, the diverticulum should be removed as complications may occur at any time. The aim of this study was to describe the findings of concomitant presence of Meckel's diverticulum who had surgical intervention in symptomatic intestinal ascariasis in children. Methods A retrospective case review study of 14 children who had surgical intervention for symptomatic intestinal ascariasis having the presence of concomitant Meckel's diverticulum was done. The study was done at SMHS Hospital Srinagar, Kashmir. Results A total of the 14 children who had ascaridial intestinal obstruction with concomitant presence of Meckel's diverticulum were studied. Age of children ranged from 4-12 years, male:female ratio was 1.8:1. Nine patients had asymptomatic Meckel's diverticulum, whereas 5 patients with symptomatic signs were found in the course of emergency surgery for ascaridial intestinal obstruction. Conclusion Meckel's diverticulum in intestinal ascariasis may pursue silent course or may be accompanied with complications of the diverticulitis, perforation or the gangrene. Incidental finding of the Meckel's diverticulum in the intestinal ascariasis should have removal.

  12. Ultrasound in the diagnosis of roundworms in gallbladder and common bile duct. Report of four cases.

    Gomez, N A; Leon, C J; Ortiz, O

    1993-01-01

    Four patients who complained of symptoms and signs compatible with biliary tract disease and in whom the diagnosis of gallbladder (three cases) and common bile duct ascariasis (one case) was made sonographically are reported. In two patients with gallbladder ascariasis, cholecystectomy corroborated the presence of the round-worms, and was curative. The third patient was a pregnant woman (32nd gestational week) who took piperazine citrate, and a second sonogram performed 29 days later was completely normal. The fourth patient with common bile duct ascariasis underwent choledochotomy with extraction of one ascaris lumbricoides from the common duct, and a T tube was left in place for 15 days. All patients received antiparasitics and had a favorable outcome. Ultrasonography is an important noninvasive diagnostic procedure in the work-up of these patients, who usually describe a clinical picture suggesting gallstone disease: this is especially true in the presence of pregnancy. PMID:8351609

  13. First Case of Ascaris lumbricoides Infestation Complicated with Hemophagocytic Lymphohistiocytosis.

    Bayhan, Gülsüm İclal; Çenesiz, Funda; Tanır, Gönül; Taylan Özkan, Ayşegül; Çınar, Gökçe

    2015-06-01

    Ascariasis is a common soil-transmitted helminth infestation worldwide. Ascaris lumbricoides infestation is generally asymptomatic or cause nonspecific signs and symptoms. We report a 5-year-old male with hemophagocytic lymphohistiocytosis associated with A. lumbricoides infestation. The presented patient recovered completely after defecating an A. lumbricoides following intravenous immunoglobulin (IVIG) and mebendazole treatment. We wanted to emphasize that because helminth infestation is easily overlooked, the diagnosis of ascariasis should be considered in patients who live in endemic areas and treated timely to prevent severe complications. PMID:26081893

  14. Genetic diversity of Ascaris in southwestern Uganda

    Betson, Martha; Nejsum, Peter; Llewellyn-Hughes, Julia;

    2012-01-01

    Despite the common occurrence of ascariasis in southwestern Uganda, helminth control in the region has been limited. To gain further insights into the genetic diversity of Ascaris in this area, a parasitological survey in mothers (n=41) and children (n=74) living in two villages, Habutobere and M...

  15. Colecistite aguda por ascaris lumbricoides Acute cholecystites for ascaris lumbricoides

    Amauri Clemente da Rocha

    2006-08-01

    Full Text Available Biliary’s ascariasis is the most often ectopic site of this helminthiasis, but invasion of the worms into the gallbladder is quite rare. The autors report a case of a patient with clinical symptoms, compatible with cholecystitis induced by the worm, as shown by ultrasonography. Treatament was cholecystectomy and antihelmintic drug therapy with a good outcome.

  16. Significance of Charcot Leyden crystals in hepatic aspirates

    Misra Vatsala

    2009-01-01

    Full Text Available Charcot Leyden crystals are hexagonal bipyramidal structures localised in the primary granules of the cytoplasm of eosinophils and basophils. Their presence, along with eosinophilic infiltrate, is an indirect evidence of parasitic infestation particularly with Toxocara, Capilliriasis, Ascariasis, or Fasciola. We report here two cases where Charcot Leyden crystals with eosinophilic infiltrate were found in the smears prepared from hepatic abscess.

  17. Massive Infestation of the biliary duct for Ascaris lumbricoides: case report

    We present a case of a woman who arrived with acute cholangitis symptomatology, and was diagnosed preoperatively by ultrasound as biliary ascariasis. During surgery, we extracted 32 worms of Ascaris lumbricoides from the Gallbladder and the common bile duct. Clinical outcome was successful, with out retention of worms

  18. Parasitic diseases

    Foundations of roentgenological semiotics of parasitic diseases of lungs, w hich are of the greatest practical value, are presented. Roentgenological pictu res of the following parasitic diseases: hydatid and alveolar echinococcosis, pa ragonimiasis, toxoplasmosis, ascariasis, amebiasis, bilharziasis (Schistosomias is) of lungs, are considered

  19. Post-partum pyogenic abscess containing Ascaris lumbricoides

    Hamid, Raashid; Wani, Sajad; Ahmad, Nawab; Akhter, Afrozah

    2013-01-01

    We report an unusual case of multiple pyogenic liver abscesses containing Ascariasis lumbricoides in a 35-year-old post-partum female who had delivered 1 month back. Open drainage of liver abscess along with liver worm was done. Patient did well post-operatively.

  20. Ascaris lumbricoides: an unusual aetiology of gastric perforation

    Gupta, Shahana; Kumar, Sanjeev; Satapathy, Ayusman; Ray, Udipta; Chatterjee, Souvik; Choudhury, Tamal Kanti

    2012-01-01

    Gastrointestinal (GI) infestation with Ascaris lumbricoides is common in the tropical countries, particularly in children. A wide range of clinical presentations are reported for GI ascariasis in both adults and children. We report a case of gastric perforation due to Ascaris, a rare presentation.

  1. Colecistite aguda por ascaris lumbricoides Acute cholecystites for ascaris lumbricoides

    Amauri Clemente da Rocha; Severino Lourenço da Silva Júnior; Rodrigo Fernando Lourenço de Amorim

    2006-01-01

    Biliary’s ascariasis is the most often ectopic site of this helminthiasis, but invasion of the worms into the gallbladder is quite rare. The autors report a case of a patient with clinical symptoms, compatible with cholecystitis induced by the worm, as shown by ultrasonography. Treatament was cholecystectomy and antihelmintic drug therapy with a good outcome.

  2. SURGICAL COMPLICATION OF ASCARIDOSIS IN ISFAHAN

    H. Emami

    1977-03-01

    Full Text Available Ascaris infestation is still prevalent in the world. In Isfahan approximately 77.7 to 90.3 percent of the population is infected. In this communication surgical complications of ascariasis in a series of 29 patients observed in Soraya Hospital of Isfahan during five year period since 1971 are reported. Intestinal obstruction was the commonest complication leading to operation (22 cases. The diagnosis was based on clinical and radiologic grounds and was confirmed at operation. In these situations enterotomy or resection of the gut was associated with high mortality. Three cases of intestinal perforation, two cases of appendicitis, one case of biliary obstruction and liver abscess and a case of acute pancreatitis due to ascariasis are also reported.

  3. Anthelmintic properties of traditional African and Caribbean medicinal plants: identification of extracts with potent activity against Ascaris suum in vitro

    Williams Andrew R.

    2016-01-01

    Full Text Available Ascariasis affects more than 1 billion people worldwide, mainly in developing countries, causing substantial morbidity. Current treatments for Ascaris infection are based on mass drug administration (MDA with synthetic anthelmintic drugs such as albendazole, however continual re-infection and the threat of drug resistance mean that complementary treatment options would be highly valuable. Here, we screened ethanolic extracts from 29 medicinal plants used in Africa (Ghana and the Caribbean (US Virgin Islands for in vitro anthelmintic properties against Ascaris suum, a swine parasite that is very closely related to the human A. lumbricoides. A wide variety of activities were seen in the extracts, from negligible to potent. Extracts from Clausena anisata, Zanthoxylum zanthoxyloides and Punica granatum were identified as the most potent with EC50 values of 74, 97 and 164 μg/mL, respectively. Our results encourage further investigation of their use as complementary treatment options for ascariasis, alongside MDA.

  4. Antihelmínticos como factor de riesgo en la obstrucción intestinal por Ascaris lumbricoides en niños Anthelmintics as a risk factor of the intestinal obstruction by Ascaris lumbricoides in children

    Oscar Vásquez Tsuji; Pedro Gutiérrez Castrellón; Marco Antonio Yamazaki Nakashimada; Juan Carlos Arredondo Suárez; Teresita Campos Rivera; Ignacio Martínez Barbosa

    2000-01-01

    In a retrospective study the authors analyzed the clinical records of 199 children ages one month to 16 years hospitalized, with the diagnosis of intestinal ascariasis, in the Instituto Nacional de Pediatria of Mexico from 1984 to 1999. The purpose of the study was to evaluate the use of anthelmintics drugs as a risk factor of intestinal obstruction by A. lumbricoides. Two groups were made for the study: Group A (n=66) of children who presented intestinal obstruction, Group B (n=133) children...

  5. Air in the Wirsung Duct. An Unusual Finding

    Carla Brindisi; Lucia Calculli; Riccardo Casadei; Raffaele Pezzilli

    2008-01-01

    Air in the pancreas is frequently reported to be associated with an abscess or a pancreatic fistula but has also been demonstrated in normal pancreatic glands. Air in the Wirsung duct has been reported in three pediatric patients with duodenal obstruction [1], in a child with biliary and pancreatic ascariasis with liver abscesses and a pancreatic pseudocyst [2], in an adult patient with cystic dilatation of the main pancreatic duct limited to the head [3], and in 11 patients with various acut...

  6. Hubungan Antara Hygiene dan Sanitasi Lingkungan Dengan Kejadian Askariasis Pada Anak SD Negeri 068426 Belawan

    Umra, Mina

    2011-01-01

    Ascariasis is one of intestinal worm infected most 2- 10 years old children mainly in developing countries included Indonesia. Askariasis prevalence in north sumatera is 46-75 % and in pediatric department of Pirngadi Hospital medan is 55,8%. Soil transmitted helminthes (STH) occured frequently in a place with bad hygiene and sanitation like along beach line belawan medan. Although wellness prognosis of this desease is 70-99%, nevertheless still able caused growth disorder among children. ...

  7. Ultrasonographic findings of ascaris in the small bowel: A case report

    Kim, Hyun Cheol; Shin, Hyeong Cheol; Kim, Hyung Hwan; Bae, Won Kyung; Kim, Il Young [Cheonan Hospital, Soonchunhyang University college of Medicine, Cheonan (Korea, Republic of); Park, Seong Jin [Bucheon Hospital, Soonchunhyang University college of Medicine, Bucheon (Korea, Republic of); Choi, Jin Soo [Keimyung University college of Medicine, Taegu (Korea, Republic of)

    2003-12-15

    Ascariasis is one of the most common helminthic disease worldwide and evoked variable clinical manifestations by the migration of worm in the alimentary and biliary tract. The ultrasonographic detection of ascaris in the small bowel is relatively difficult, and no report on the ultrasonographic findings have been published in Korea. On abdominal ultrasonography, ascaris is seen as an intraluminal tubular structure with 4 linear echogenic stripes and movement. We report a case of ascaris in the small bowel detected by abdominal ultrasonography.

  8. [ULTRASOUND DIAGNOSIS OF PARASITIC INVASION OF THE GALLBLADDER].

    Kostyuchenko, M V; Dolotova, V N

    2015-01-01

    Migration of ascaris from the lumen of the small intestine to the biliary system was previously thought to be very rare pathology and the diagnosis had not be without specific examination methods. At the present time widespread active ultrasonic technologies in the emergency surgical service can became more accessible to show worm in a gall bladder and ducts. The paper presents two cases of gallbladder ascariasis, identified by ultrasound. PMID:27017754

  9. Hubungan Askariasis dengan Kadar Eosinofil di SDN 060923 Medan Amplas Tahun 2015

    Purba, Yenny

    2016-01-01

    Background. Elementary school age children is the most susceptible to intestinal worms, because the behavior of children who lack personal hygiene keep. An increase in eosinophils is often associated with diseases caused by worms and allergies. Eosinofilia is a general marker of the presence of the worm infection. Objective. Relationship ascariasis with levels of eosinophils in students SDN 060923 Medan Amplas Method. Research with design study using the method of cross sect...

  10. Pathology of tropical appendicitis.

    S. C. Gupta; A. K. Gupta; Keswani, N. K.; Singh, P. A.; Tripathi, A.K.; Krishna, V.

    1989-01-01

    Over the past 25 years, 2921 appendicectomies were performed at this hospital. All were subjected to routine histopathological examination. In 95% of cases, histopathological examination did not add any further information but in 153 (5%) cases, clinically important pathological findings were detected for the first time. Seventy (2.3%) specimens showed typical evidence of tuberculosis. Parasitic infestation was detected in 75 (2.5%), including enterobiasis (1.4%), amoebiasis (0.5%), ascariasi...

  11. Small bowel Ascaris infestation: a diagnostic challenge.

    Khan, Muhammad Waqas; Ghauri, Sanniya Khan

    2016-01-01

    Ascariasis is a common infestation in developing countries where there is poor hygiene. A majority of the cases are asymptomatic, with a few cases presenting with mild abdominal pain and nutritional deficiencies in the long term. Here we present a case of a young boy who presented as a diagnostic dilemma, with signs of acute intestinal obstruction without any supporting radiological evidence. A barium study revealed the presence of low-burden Ascaris infestation that was managed medically. PMID:27175091

  12. Ultrasonographic findings of ascaris in the small bowel: A case report

    Ascariasis is one of the most common helminthic disease worldwide and evoked variable clinical manifestations by the migration of worm in the alimentary and biliary tract. The ultrasonographic detection of ascaris in the small bowel is relatively difficult, and no report on the ultrasonographic findings have been published in Korea. On abdominal ultrasonography, ascaris is seen as an intraluminal tubular structure with 4 linear echogenic stripes and movement. We report a case of ascaris in the small bowel detected by abdominal ultrasonography.

  13. Encountering Meckel's diverticulum in emergency surgery for ascaridial intestinal obstruction

    Amin Abid; Wani Muddasir; Wani Shadab; Naikoo Ghulam; Šnábel Viliam; Wani Imtiaz; Sheikh Tariq; Parray Fazal Q; Wani Rauf A

    2010-01-01

    Abstract Background Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract. In children with intestinal ascariasis, the diverticulum remains asymptomatic or rarely the Ascaris lumbricoides may lead to its complications in the presence of massive intestinal roundworm load. Given that preoperative diagnosis is seldom carried out, when Meckel's diverticulum is found at laparotomy for obstructive intestinal complications of roundworm, the diverticulum should be ...

  14. Small bowel Ascaris infestation: a diagnostic challenge

    Khan MW; Ghauri SK

    2016-01-01

    Muhammad Waqas Khan, Sanniya Khan Ghauri Section of Medicine, Department of Emergency Medicine, WHO Collaborating Centre for Emergency Medicine and Trauma Care, Aga Khan University Hospital, Karachi, Pakistan Abstract: Ascariasis is a common infestation in developing countries where there is poor hygiene. A majority of the cases are asymptomatic, with a few cases presenting with mild abdominal pain and nutritional deficiencies in the long term. Here we present a case of a young boy who prese...

  15. Presensitization to Ascaris antigens promotes induction of mite-specific IgE upon mite antigen inhalation in mice

    Mayu Suzuki; Mutsuko Hara; Saori Ichikawa; Seiji Kamijo; Takuya Nakazawa; Hideki Hatanaka; Kazuo Akiyama; Hideoki Ogawa; Ko Okumura; Toshiro Takai

    2016-01-01

    Background: Patients with house dust mite (HDM) allergy or Ascariasis produce serum IgE specific to the antigens of HDM or nematode Ascaris, respectively. Although human IgE cross-reactivity has been reported between HDM and Ascaris antigens, it remains unclear whether it contributes to the pathogenesis of allergic diseases. We herein investigated the induction of cross-reactive antibodies and T cells in mice and effects of airway exposure to HDM antigens after preimmunization with Ascaris an...

  16. Internal Transcribed Spacer 1 (ITS1) based sequence typing reveals phylogenetically distinct Ascaris population

    Koushik Das; Punam Chowdhury; Sandipan Ganguly

    2015-01-01

    Taxonomic differentiation among morphologically identical Ascaris species is a debatable scientific issue in the context of Ascariasis epidemiology. To explain the disease epidemiology and also the taxonomic position of different Ascaris species, genome information of infecting strains from endemic areas throughout the world is certainly crucial. Ascaris population from human has been genetically characterized based on the widely used genetic marker, internal transcribed spacer1 (ITS1). Along...

  17. Complete Mitochondrial Genomes of Chimpanzee- and Gibbon-Derived Ascaris Isolated from a Zoological Garden in Southwest China

    Yue Xie; Lili Niu; Bo Zhao; Qiang Wang; Xiang Nong; Lin Chen; Xuan Zhou; Xiaobin Gu; Shuxian Wang; Xuerong Peng; Guangyou Yang

    2013-01-01

    Roundworms (Ascaridida: Nematoda), one of the most common soil-transmitted helminths (STHs), can cause ascariasis in various hosts worldwide, ranging from wild to domestic animals and humans. Despite the veterinary and health importance of the Ascaridida species, little or no attention has been paid to roundworms infecting wild animals including non-human primates due to the current taxon sampling and survey bias in this order. Importantly, there has been considerable controversy over the yea...

  18. Esophageal space-occupying lesion caused by Ascaris lumbricoides

    Zheng, Ping-Ping; Wang, Bing-Yuan; Wang, Fei; Ao, Ran; Wang, Ying(School of Physics, Shandong University, Jinan, 250100, PR China)

    2012-01-01

    Ascaris lumbricoides is the largest intestinal nematode parasite of man, which can lead to various complications because of its mobility. As the esophagus is not normal habitat of Ascaris, the report of esophageal ascariasis is rare. An old female presented with dysphagia after an intake of several red bean buns and haw jellies. The barium meal examination revealed a spherical defect in the lower esophagus. Esophageal bezoar or esophageal carcinoma was considered at the beginning. The patient...

  19. Round worm in common bile duct, a rare pathology: Review of 15 cases

    Biswaranjan Nayak; Rashmi Rani Dash; Biranchi Narayan Mallik

    2014-01-01

    Round worm or Ascaris lumbricoides has a worldwide distribution but is more prevalent in the developing countries like India and other South Asian countries. In human beings, round worms are commonly found in the small intestine, particularly the jejunum. If the pathogen load is very high, it may migrate to other sites and manifest different symptoms. In this paper, we share our experience of biliary ascariasis with regards to its clinical presentation, diagnosis, conservative and surgical ma...

  20. Round worm in common bile duct, a rare pathology: Review of 15 cases

    Biswaranjan Nayak

    2014-01-01

    Full Text Available Round worm or Ascaris lumbricoides has a worldwide distribution but is more prevalent in the developing countries like India and other South Asian countries. In human beings, round worms are commonly found in the small intestine, particularly the jejunum. If the pathogen load is very high, it may migrate to other sites and manifest different symptoms. In this paper, we share our experience of biliary ascariasis with regards to its clinical presentation, diagnosis, conservative and surgical management.

  1. Successful treatment of lipoid pneumonia associated with bowel obstruction by Ascaris lumbricoides.

    Azevedo Sias, Selma; Oliveira Caetano, Regina; Dutra Comarella, Júlia; de Oliveira, Elen; Santos Ferreira, Angela; Quirico-Santos, Thereza

    2011-08-01

    Partial bowel obstruction is a serious complication of ascariasis infestation generally treated with mineral oil. This prospective study aimed to evaluate the efficacy of multiple bronchoalveolar lavages (BAL) as a therapeutic strategy for reducing lung inflammation of lipoid pneumonia associated with ascariasis. The study included five children (mean age 25 months) with partial small-bowel obstruction by Ascaris lumbricoides, who underwent diagnostic bronchoalveolar lavage for assessment of refractory pneumonia. Routine biochemical, microbiological and cytological analysis were carried out in the BAL. Protein, lactate dehydrogenase and tumor necrosis factor-alpha (TNF-α) cytokine levels were determined in the serum before and after treatment. At admission, children consistently had respiratory symptoms, altered hematological function, increased immunoglobulin E serum level and peripheral blood eosinophilia. Chest tomography showed consolidation with air bronchogram (4/4), ground-glass infiltration (3/4) and decreased attenuation in the consolidation areas (2/4). Presence of marked pleocytosis with Sudan positive foamy alveolar macrophages, high protein and lactate dehydrogenase levels in the BAL indicated presence of mixed alveolitis. One child with extensive consolidation and air bronchogram in both lungs died before treatment. Multiple bronchoalveolar lavages efficiently removed alveolar oil deposits, restored BAL cellularity, improved clinical symptoms, radiological parameters and further reduced inflammatory reaction evidenced by marked decrease of the inflammatory cytokine, TNF-α. This study presents a therapeutic strategy for management of lung complications caused by mineral oil administration to treat intestinal bowel obstruction associated with ascariasis. PMID:20026557

  2. ASCARIDIA COLUMBAE IN COLUMBIA LIVIA DOMESTICA

    B. Bizhga

    2011-09-01

    Full Text Available Ascaridia columbae is the cause of ascariasis in pigeons. The object of this study carried out in Tirana and Lushnja was the presence of ascariasis, identification and parasite load in pigeons (Columbia livia domestica. 5 dead pigeons were examined, 8 others were sacrificed and fecal samples were examined repeatedly, taken from 2 coops with pigeons, 1 for each area out of a total of 192 poultry. Ascaridia columbae was frequently evidenced in the pigeons of our country. Its prevalence results relatively high and varies from 40-90 % of the pigeons. We think that the cause of high affection of Ascaridia columbae is due to the lack of dehelminth culture and prophylactic precautions in cages. Average parasite load resulted 124 v/g/f with significant variations in the values 60-180 v/g/f. Adult ascariasis was identified based on morphological characteristics and the number of the parasites grown within the intestines of the poultry were defined. The number of the adult parasites that colonize the intestines of the poultry resulted 4-8 parasites on average. But there were also sporadic cases which evidenced up to 24 patent ascribes grown in intestines. In these cases nervous phenomena were evidenced as well as problems of condition, nutrition, mal growth, which might be the cause of a compromising diagnosis with other diseases of the pigeons. The study identified Ascaridia columbae as the cause of ascaridiosis in pigeons and a prevalence and parasite load that makes the application of diagnostic precautions and dehelminth schemes indispensable, whose lack is the cause of such condition.

  3. Albendazole in the treatment of intestinal helminthiasis in children.

    Misra, P K; Pande, N K; Jagota, S C

    1985-01-01

    A single dose of 2% albendazole suspension (400 mg in 20 ml) was administered to 77 patients (42 males and 35 females), ages ranging between 2 to 12 years, with helminthic infections. Ascariasis was the most prevalent infection. Patients were followed-up for 3 weeks. The results showed that albendazole was highly effective against Ascaris lumbricoides, Ancylostoma duodenale and Enterobius vermicularis. Significant improvement was also observed in patients having infections due to Trichuris trichiura. Albendazole was well tolerated and did not produce any significant side-effects. Single dose albendazole appears to be appropriate for mass chemotherapy to control intestinal nematode infections in highly infected communities. PMID:4028809

  4. Recurrent Abdominal Pain in Preschool Children.

    * Ritu Gupta, **Ravinder K. Gupta

    2004-01-01

    One hundred fifty preschool children with recurrent abdominal pain (RAP) were studied. Organiccause was observed in 135 (90%) and non-organic in 15 (10%). Giardiasis was the commonestorganic cause in 81 (60%) either alone or with other parasites followed by ascariasis 27 (20%) alone.Other cause of organic pain were urinary tract infection (UTI) 9 (6.7%), abdominal tuberculosis 9(6.7%), eosophagitis/gastritis 4 (2.9%) and gall stones 2 (1.4%). School phobia, sibling rivalry,unpleasant relation...

  5. Should intensivist do routine abdominal ultrasound?

    Sukhen Samanta

    2015-01-01

    Full Text Available Roundworm infestation is common in tropical climate population with a low socioeconomic status. We describe a case of a young male with polytrauma accident who presented with small bowel dysfunction with a high gastric residual volume during enteral feeding. While searching the etiology, the intensivist performed bedside abdominal ultrasound (USG as a part of whole body USG screening along with clinical examination using different frequency probes to examine bowel movement and ultimately found ascariasis to be the cause. This case report will boost up the wide use of bedside USG by critical care physicians in their patient workup.

  6. Recurrent Abdominal Pain in Preschool Children.

    Ritu Gupta, Ravinder K Gupta

    2004-01-01

    Full Text Available One hundred fifty preschool children with recurrent abdominal pain (RAP were studied. Organiccause was observed in 135 (90% and non-organic in 15 (10%. Giardiasis was the commonestorganic cause in 81 (60% either alone or with other parasites followed by ascariasis 27 (20% alone.Other cause of organic pain were urinary tract infection (UTI 9 (6.7%, abdominal tuberculosis 9(6.7%, eosophagitis/gastritis 4 (2.9% and gall stones 2 (1.4%. School phobia, sibling rivalry,unpleasant relations among parents and nocturnal enuresis were significant factors associated withnon-organic causes.

  7. Should intensivist do routine abdominal ultrasound?

    Samanta, Sukhen; Samanta, Sujay; Soni, Kapil Dev; Aggarwal, Richa

    2015-09-01

    Roundworm infestation is common in tropical climate population with a low socioeconomic status. We describe a case of a young male with polytrauma accident who presented with small bowel dysfunction with a high gastric residual volume during enteral feeding. While searching the etiology, the intensivist performed bedside abdominal ultrasound (USG) as a part of whole body USG screening along with clinical examination using different frequency probes to examine bowel movement and ultimately found ascariasis to be the cause. This case report will boost up the wide use of bedside USG by critical care physicians in their patient workup. PMID:26430346

  8. Focal inflammatory diseases of the liver

    Inflammatory lesions constitute an important subgroup of focal liver lesions. They may mimic primary or metastatic neoplastic lesions and their differentiation from neoplasia is clinically very important since management of the patient significantly changes. Radiologists should have an important role in both the diagnosis and therapy of these lesions by performing percutaneous aspirations and drainages. In this review we discussed the radiological findings of pyogenic abscesses, amebic abscesses, candidiasis, tuberculosis, hydatic cysts, fascioliasis, ascariasis, schistosomiasis, and sarcoidosis with a special emphasis on US, CT and MR characteristics

  9. Focal inflammatory diseases of the liver

    Oto, Aytekin; Akhan, Okan; Oezmen, Mustafa

    1999-10-01

    Inflammatory lesions constitute an important subgroup of focal liver lesions. They may mimic primary or metastatic neoplastic lesions and their differentiation from neoplasia is clinically very important since management of the patient significantly changes. Radiologists should have an important role in both the diagnosis and therapy of these lesions by performing percutaneous aspirations and drainages. In this review we discussed the radiological findings of pyogenic abscesses, amebic abscesses, candidiasis, tuberculosis, hydatic cysts, fascioliasis, ascariasis, schistosomiasis, and sarcoidosis with a special emphasis on US, CT and MR characteristics.

  10. Antigen recognition by IgG4 antibodies in human trichinellosis

    Pinelli E.

    2001-06-01

    Full Text Available The antibody isotype response to Trichinella spiralis excretory/secretory (ES products of muscle larva was examined using sera from patients with confirmed trichinellosis. Using Western blots we identify components of the ES antigen that are recognized by IgM and IgG antibodies. A 45 kDa component was strongly recognized by different antibody classes and subclasses. We observed a 45 kDa-specific lgG4 response that was detected exclusively using sera of patients with trichinellosis and not of patients with echinococcosis, filariasis, cysticercosis, ascariasis, strongyloidiasis or toxocariasis. These results are relevant for the diagnosis of human trichinellosis.

  11. PREDOMINANCE AND SOCIAL DETERMINANTS IN OCCURRENCE OF PARASITOSIS IN CENTEREASTERN REGION OF PARANÁ: A SOCIOECONOMIC ANALYZES OF THE PROBLEM.

    Patricia Regina Cenci Queiroz, Angela Patricia Motin, Cristiane Aparecida Verbaneck, Franciely Damaris de Cristo, Marcia de Souza Oliveira, Marcia Maria Veronese e Shirley Rak Mantovani

    2006-12-01

    Full Text Available Considering the high incidence of parasitic diseases in centereastern region of Paraná, an inquiry about its probable determinants was carried out. Particularly, the occurrence of Ascaris Lumbricoides was analyzed. Bibliographical research referring to this theme and data-collecting from centereastern region have been carried out, attempting to contextualize the epidemiological condition of this region. We can conclude that the high occurrence of ascariasis in analyzed region is linked to life conditions of general population, the deficiency in urban and sanitary planning, socioeconomic conditions and, essentially, the absence of investments in basic infrastructure. Thus, this study demonstrates the need of an urgent prophylactic action.

  12. El grado de agregación de Ascaris lumbricoides según grupos de edad, después de una intervención antihelmíntica de masas

    Agustín Ruíz; Guadalupe Ocampo; Araceli Soto; José, Marco V.

    1996-01-01

    Objetivo. Describir la heterogeneidad de la reinfección por Ascaris lumbricoides según grupos de edad, en distintos intervalos, después de un primer tratamiento antihelmíntico masivo. Material y métodos. A partir de datos de la prevalencia e intensidad de la infección por A. lumbricoides obtenidos en un estudio epidemiológico de ascariasis, realizado en Coatzacoalcos, Veracruz, México, se deriva el grado de agregación por medio del método de máxima verosimilitud, asumiendo una distribución bi...

  13. Potensi Serbuk Daun Kelor (Moringa oleifera Sebagai Anthelmintik Terhadap Infeksi Ascaris suum dan Feed Supplement pada Babi

    Muhammad Ulqiya Syukron

    2015-06-01

    Full Text Available Pig ascariasis is an intestinal parasitic disease caused by Ascaris suum. The economic losses in pig ascariasis are caused by a bad feed conversion ratio (FCR and rejection of some organs after animal slaughtering. An anthelmintic utilization and farm management improvement are the common prevention action, however, recently the utilization of herbs as an athelmintic has been developed, one of them is Moringa oleifera leaves. Moringa oleifera leaves are also a potential for a sources of animal food because of their high nutrients. This intervention research aimed to examine the anthelmintic effect of Moringa oleifera leaves and its potency as feed supplement. Experimental design used was ccompletely randomized design split time (CRD Split Time with six treatments namely Moringa oleifera 5% and an infection of infective larvae of A. suum (1, Moringa oleifera 5% (2, positive control (3, Moringa oleifera 10% (4, Moringa oleifera 10% and infection of infective larvae of A. suum (5, and no treatment as negative control (6. Each treatment was imposed on four female landrace piglets aged 8 weeks and weighed around 11 kg. The results showed that Moringa oleifera 5% and 10% of the feed could inhibit the egg production of A.suum and had a significant effect (P<0.05 on weight gain of piglets. It can be concluded that Moringa oleifera leave have an anthelmintic effect to prevent the infection of A. suum and a potential for a feed supplement on pigs.

  14. Medical image of the week: ascaris lumbridoies

    Wong C

    2015-02-01

    Full Text Available No abstract available. Article truncated at 150 words. A 25 year-old man was admitted to the ICU with acute renal failure and acute respiratory failure from fluid overload after attempting to cross the border. The patient was successfully extubated after five days of mechanical ventilation and renal replacement therapy. Following extubation, the patient had a bowel movement and passed a 23cm adult Ascaris lumbricoides. He was treated with a single dose of albendazole 400 mg. Ascariasis is a very common helminthic infection, particularly in pediatric populations, and affects mostly the gastrointestinal tract. When infective eggs are swallowed by the host, larvae hatch in the GI tract. The larvae invade the GI mucosa and then are brought into the lungs via portal circulation. The larvae can then move up the tracheobronchial tree and then are swallowed into the GI tract where the mature worms form (1. While our patient had a simple gastrointestinal infection, several pulmonary complications of ascariasis ...

  15. Internal Transcribed Spacer 1 (ITS1 based sequence typing reveals phylogenetically distinct Ascaris population

    Koushik Das

    2015-01-01

    Full Text Available Taxonomic differentiation among morphologically identical Ascaris species is a debatable scientific issue in the context of Ascariasis epidemiology. To explain the disease epidemiology and also the taxonomic position of different Ascaris species, genome information of infecting strains from endemic areas throughout the world is certainly crucial. Ascaris population from human has been genetically characterized based on the widely used genetic marker, internal transcribed spacer1 (ITS1. Along with previously reported and prevalent genotype G1, 8 new sequence variants of ITS1 have been identified. Genotype G1 was significantly present among female patients aged between 10 to 15 years. Intragenic linkage disequilibrium (LD analysis at target locus within our study population has identified an incomplete LD value with potential recombination events. A separate cluster of Indian isolates with high bootstrap value indicate their distinct phylogenetic position in comparison to the global Ascaris population. Genetic shuffling through recombination could be a possible reason for high population diversity and frequent emergence of new sequence variants, identified in present and other previous studies. This study explores the genetic organization of Indian Ascaris population for the first time which certainly includes some fundamental information on the molecular epidemiology of Ascariasis.

  16. Internal Transcribed Spacer 1 (ITS1) based sequence typing reveals phylogenetically distinct Ascaris population.

    Das, Koushik; Chowdhury, Punam; Ganguly, Sandipan

    2015-01-01

    Taxonomic differentiation among morphologically identical Ascaris species is a debatable scientific issue in the context of Ascariasis epidemiology. To explain the disease epidemiology and also the taxonomic position of different Ascaris species, genome information of infecting strains from endemic areas throughout the world is certainly crucial. Ascaris population from human has been genetically characterized based on the widely used genetic marker, internal transcribed spacer1 (ITS1). Along with previously reported and prevalent genotype G1, 8 new sequence variants of ITS1 have been identified. Genotype G1 was significantly present among female patients aged between 10 to 15 years. Intragenic linkage disequilibrium (LD) analysis at target locus within our study population has identified an incomplete LD value with potential recombination events. A separate cluster of Indian isolates with high bootstrap value indicate their distinct phylogenetic position in comparison to the global Ascaris population. Genetic shuffling through recombination could be a possible reason for high population diversity and frequent emergence of new sequence variants, identified in present and other previous studies. This study explores the genetic organization of Indian Ascaris population for the first time which certainly includes some fundamental information on the molecular epidemiology of Ascariasis. PMID:26504510

  17. Esophageal space-occupying lesion caused by Ascaris lumbricoides

    Ping-Ping Zheng; Bing-Yuan Wang; Fei Wang; Ran Ao; Ying Wang

    2012-01-01

    Ascaris lumbricoides is the largest intestinal nematode parasite of man,which can lead to various complications because of its mobility.As the esophagus is not normal habitat of Ascaris,the report of esophageal ascariasis is rare.An old female presented with dysphagia after an intake of several red bean buns and haw jellies.The barium meal examination revealed a spherical defect in the lower esophagus.Esophageal bezoar or esophageal carcinoma was considered at the beginning.The patient fasted,and received fluid replacement treatment as well as some oral drugs such as proton pump inhibitor and sodium bicarbonate.Then upper gastrointestinal endoscopy was done to further confirm the diagnosis and found a live Ascaris lumbricoides in the gastric antrum and two in the duodenal bulb.The conclusive diagnosis was ascariasis.The esophageal space-occupying lesion might be the entangled worm bolus.Anthelmitnic treatment with mebendazole improved patient's clinical manifestations along with normalization of the radiological findings during a 2-wk follow-up.Authors report herein this rare case of Ascaris lumbricoides in the esophagus,emphasizing the importance of awareness of this parasitic infection as it often presents with different and unspecific symptoms.

  18. Hubungan Sanitasi Lingkungan Rumah dengan Kejadian Askariasis dan Trikuriasis pada Siswa SD N 29 Purus Padang

    Hildya Kusmi

    2015-09-01

    clean water source, garbage disposal facilities and the type of floor home to ascariasis and trichuriasis incidences . This  was an analyticwith cross sectional study design. The population were  71  students of State Elementery School 29 Purus Padang, but the subjecs were  55 students. Research instruments were stool examination and questionnaire. Bi variate analysis was chi-square test. The results showed that the worm infection rate in student of Elementary School 29 Purus Padangwas 38 %, consist of Ascaris lumbricoides infection (33%, Trichuris trichiura infection (9.1% and infection of both species (3.6%. The statistical test indicated no significant relationship between latrine ownership, availability of clean water source, garbage disposal facilities, and the type of floor home to the incidence of ascariasis and trichuriasis (p > 0.05. The high worm infection in elementary school students need better attention, like worm eradication program by the school and local health authorities.Keywords: worm infestations, environmental sanitation, ascariasis, trichuriasis 

  19. Mucocutaneous manifestations of helminth infections: Nematodes.

    Lupi, Omar; Downing, Christopher; Lee, Michael; Pino, Livia; Bravo, Francisco; Giglio, Patricia; Sethi, Aisha; Klaus, Sidney; Sangueza, Omar P; Fuller, Claire; Mendoza, Natalia; Ladizinski, Barry; Woc-Colburn, Laila; Tyring, Stephen K

    2015-12-01

    In the 21st century, despite increased globalization through international travel for business, medical volunteerism, pleasure, and immigration/refugees into the United States, there is little published in the dermatology literature regarding the cutaneous manifestations of helminth infections. Approximately 17% of travelers seek medical care because of cutaneous disorders, many related to infectious etiologies. This review will focus on the cutaneous manifestations of helminth infections and is divided into 2 parts: part I focuses on nematode infections, and part II focuses on trematode and cestode infections. This review highlights the clinical manifestations, transmission, diagnosis, and treatment of helminth infections. Nematodes are roundworms that cause diseases with cutaneous manifestations, such as cutaneous larval migrans, onchocerciasis, filariasis, gnathostomiasis, loiasis, dracunculiasis, strongyloidiasis, ascariasis, streptocerciasis, dirofilariasis, and trichinosis. Tremadotes, also known as flukes, cause schistosomiasis, paragonimiasis, and fascioliasis. Cestodes (tapeworms) are flat, hermaphroditic parasites that cause diseases such as sparganosis, cysticercosis, and echinococcus. PMID:26568337

  20. Prevalence of diseases of pigs in Botswana

    John Cassius Moreki,

    2011-07-01

    Full Text Available This paper is a review of diseases of pigs from 1997 to 2007. Lack of health management reduces animal performance. This review showed that bacterial and non-infectious diseases were a major challenge in pig production. The 10 most common diseases of pigs in order of importance were septicaemia, traumatic injuries/torsions, coli-septicaemia, stress, pneumonia, cystitis, colibacillosis, salmonella, mange and nutritional deficiencies with 72, 68, 53, 38, 36, 21, 18, 14, 12 and 10 cases recorded, respectively. Other diseases and conditions recorded sporadically included coccidiosis, brucellosis, toxoplasmosis, actinomyces, urolithiasis, aflatoxicosis, meningitis, pasteurella, and other miscellaneous conditions caused by microbial infestation from stomach or colic raptures. Mange and ascariasis were the main parasitic diseases recorded. The high prevalence of diseases suggests inadequacy of biosecurity measures. In order to reduce disease outbreaks and spread, strict biosecurity measures should be put in place on pig operations.

  1. Antinociceptive potential of viscosine isolated form dodonaea viscose in animal models

    Dodonaea viscosa was selected in this study based on its ethno-medicinal applications for treating various painful conditions. In earlier studies crude extracts of Dodonaea viscosa showed significant actions as local anesthetic, smooth muscle relaxant, antibacterial, anti-inflammatory, antifungal, anti-ulcerogenic, anti-ascariasis, anthelmintic, cardiac depressant, hypotensive, uterine relaxation and vasoconstrictor activity in different experimental models. In an effort to identify the potential analgesic components of the plant, the principal flavonoid constituent, 5,7,4-trihydroxy-3,6-dimethoxyflavone (viscosine) was isolated. When tested using the acetic acid-induced writhing and hot plate analgesic models, viscosine (30, 45 and 60 mg/kg), showed significant (p < 0.05) antinociceptive activity in a dose-dependent manner. It is concluded that viscosine has antinociceptive therapeutic potential through both central and peripheral mechanisms and can be used a template compound as a painkiller. (author)

  2. Helminthiases in Montes Claros. Preliminary survey

    Rina Girard Kaminsky

    1976-04-01

    Full Text Available A preliminary survey was conducted for the presence of helminths in the city of Montes Claros, M. G., Brazil. Three groups of persons were examined by the direct smear, Kato thick film and MIFC techniques; one group by direct smear and Kato only. General findings were: a high prevalence of hookworm, followed by ascariasis, S. mansoni, S. stercoralis and very light infections with T. trichiurá. E. vermicularis and H. nana were ranking parasites at an orphanage, with some hookworm and S. mansoni infections as well. At a pig slaughter house, the dominant parasites were hookworm and S. mansoni. Pig cysticercosis was an incidental finding worth mentioning for the health hazard it represents for humans as well as an economic loss. From the comparative results between the Kato and the MIF the former proved itself again as a more sensitive and reliable concentration method for helminth eggs, of low cost and easy performance.

  3. Mucocutaneous manifestations of helminth infections: Trematodes and cestodes.

    Lupi, Omar; Downing, Christopher; Lee, Michael; Bravo, Francisco; Giglio, Patricia; Woc-Colburn, Laila; Tyring, Stephen K

    2015-12-01

    In the 21st century, despite increased international travel for vacation, work, and medical missions and immigration into the United States, there is little published in the dermatology literature regarding the cutaneous manifestations of helminth infections. It has been estimated that 20% to 70% of international travelers suffer from some travel-related health problem. Approximately 17% of travelers seek medical care because of cutaneous disorders, many related to infectious etiologies. This review will focus on cutaneous diseases caused by helminth infections. Part I of the review focused on nematode infections; part II will focus on trematode and cestode infections. Nematodes are roundworms that cause diseases with cutaneous manifestations, such as cutaneous larval migrans, onchocerciasis, filariasis, gnathostomiasis, loiasis, dracunculiasis, strongyloidiasis, ascariasis, streptocerciasis, dirofilariasis, and trichinosis. Tremadotes, also known as flukes, cause schistosomiasis, paragonimiasis, and fascioliasis. Cestodes (tapeworms) are flat, hermaphroditic parasites that cause diseases such as sparganosis, cysticercosis, and echinococcus. PMID:26568338

  4. INTESTINAL PARASITES IN IRAN

    K. Mohammad

    1995-12-01

    Full Text Available The purpose of this study was to investigate the status and epidemiology of Intestinal Parasites in Iran. The information was driven from an extensive Health Survey which was done by the Ministry of Health and Medical Education, deputy of Research Affairs in 1990-92. Sampling fraction was 1 per 1000 of individuals aged between 2 and 69, the sampling method was cluster sampling and each cluster consisted of 7 families. Formal-ether was the method of finding parasites which included: Oxior, Ascariasis, Giardiasis, Entamoeba-histolytica, Tinea, Strongyloidiasis, Ancylostoma, and Trichocephaliasis. The highest prevalence rate belonged to Giardiasis with 14.4% and the lowest one belonged to Tinea and Ancylostoma with 0.2%. The prevalence rate in rural area was significantly lower than urban area (p<0.0001.

  5. Small bowel Ascaris infestation: a diagnostic challenge

    Khan MW

    2016-04-01

    Full Text Available Muhammad Waqas Khan, Sanniya Khan Ghauri Section of Medicine, Department of Emergency Medicine, WHO Collaborating Centre for Emergency Medicine and Trauma Care, Aga Khan University Hospital, Karachi, Pakistan Abstract: Ascariasis is a common infestation in developing countries where there is poor hygiene. A majority of the cases are asymptomatic, with a few cases presenting with mild abdominal pain and nutritional deficiencies in the long term. Here we present a case of a young boy who presented as a diagnostic dilemma, with signs of acute intestinal obstruction without any supporting radiological evidence. A barium study revealed the presence of low-burden Ascaris infestation that was managed medically. Keywords: partial intestinal obstruction, gastro-intestinal helminthic infection, pediatric

  6. X-ray findings of small bowel taeniasis: A clinical and experimental study

    Kim, Hong Soo; Kang, Hee Woong; Bahk, Yong Whee [St Mary' s Hospital Catholic Medical College, Seoul (Korea, Republic of)

    1972-12-15

    Unlike ascariasis of the small bowel, taeniasis can be detected radiologically with much difficulty because of the basic difference between the morphological features of each helminth. However once the characteristics of tape worms are appreciated and kept in mind, radiological diagnosis is fairly accurately made. In the present study we have reported typical radiological features of the small bowel taeniasis as observed in 6 adults patients seen at the Department of Radiology of St. Mary's Hospital and Holy Family Hospital, Catholic Medical College. Tapering tape-like or ribbon -like radiolucent shadows in distal small bowel appear unique. Compression spot film study of the ileum is most important in revealing such findings. An animal experiment using the swine small intestine and parasitological specimen of evacuated worm of taenia saginata was designed to help understand radiological manifestation in vivo.

  7. Parasitic disease of the liver and biliary tree

    Mohamed Abdulrahman

    1997-01-01

    Full Text Available Several parasites infest liver or biliary tree, either during their maturation stages or as adult worms. Bile iry tree parasites may cause pancreatitis, cholecystitis, biliary tree obstruction, recurrent cholangitis, biliary tree strictures and some may lead to cholangiocarcinoma. This review discusses the hepatobiliary parasites, and shows our experience in diagnosis and management of these parasites. Ultrasonography of the liver is diagnostic in schistosomiasis, hydatid cysts, amebic liver abscess, ascariasis and other biliary tree parasites showing bile duct dilatation. Percutaneous aspiration under ultrasonography guidance of hydatid liver cysts or amebic abscess are effective measures in management. Endoscopic retrograde cholangiopancreatography (ERCP is safe and effective in diagnosis and management of biliary tree parasites.

  8. Severity of atopic dermatitis and Ascaris lumbricoides infection: an evaluation of CCR4+ and CXCR3+ helper T cell frequency

    Maria Teresa Nascimento Silva

    2012-12-01

    Full Text Available INTRODUCTION: Ascaris lumbricoides-infected patients present lower prevalence of severe atopic dermatitis. METHODS: Peripheral blood of infected children with atopic dermatitis was assessed by flow cytometry of the frequency of Th1 and Th2 cells through the expression of CXCR3 and CCR4 chemokine receptors, respectively. RESULTS: Helminth-free patients with atopic dermatitis presented a high frequency of CCR4+Th2 cells. Parasitized patients with atopic dermatitis showed a lower frequency of CXCR3+Th1 cells compared to infected individuals only. CONCLUSIONS: Ascariasis modifies the blood traffic of Th2 cells in atopic dermatitis patients, while the allergic disease down-regulates the traffic of Th1 cells in parasitized patients.

  9. T-TUBE APPLICATION AFTER CBD EXPLORATION IS NOT ALWAYS NECESSARY: A STUDY

    Purujit

    2014-06-01

    Full Text Available BACKGROUND: Routine application of supraduodenal T-tube after choledochotomy is absolutely not necessary. T-tube application gives various complications with high morbidity and reported cases of mortality and increases hospital stay. Materials and methods-Primary closure of CBD following choledochotomy is studied on 457 cases of choledocholithiasis and biliary ascariasis with CBD diameter less than 2.5cms. Most of the cases had 1-3 stone that didn’t require much manipulation during extraction. The choledochotomy wound were closed by single layer of interrupted 3-0 vicryl suture. RESULT: Post-operative period was uneventful except transient jaundice which subsided within few days in some cases. Most of the patients were discharged after 2- 3 days. Conclusions-Primary closure of choledochotomy is routinely advocated due to many fold advantages and T-tube is considered to be applied in a very special situation.

  10. Characterization of ascaris from ecuador and zanzibar.

    Sparks, A M; Betson, M; Oviedo, G; Sandoval, C; Cooper, P J; Stothard, J R

    2015-07-01

    To shed light on the epidemiology of ascariasis in Ecuador and Zanzibar, 177 adult worms retrieved by chemo-expulsion from either people or pigs were collected, measured and subjected to polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis of the ribosomal internal transcribed spacer (ITS) region. Upon double digestion with RsaI and HaeIII, PCR-RFLP analysis revealed the presence of A. lumbricoides in people and A. suum in pigs in Ecuador. In contrast, while there are no pigs on Zanzibar, of the 56 worms obtained from people, one was genotyped as A. suum. No additional genetic variation was detected upon further PCR-RFLP analysis with several other restriction enzymes. Upon measurement, worm mass and length differed by location and by species, A. suum being lighter and longer. While there is no evidence to suggest zoonotic transmission in Ecuador, an enduring historical signature of previous zoonotic transmission remains on Zanzibar. PMID:26017334

  11. [EXPERIENCE IN TREATING HELMINTHISM WITH MICRONIZED ALBENDAZOLE (GELMODOL)].

    Zavoikin, V D; Tumolskaya, N I; Mazmanyan, M V; Zelya, O P; Tikhonova, D V

    2015-01-01

    The paper gives the results of treatment with micronized albendazole (Gelmodol-BM, World Medicine, UK) in 87 patients of the Department of Medical Parasitology and Tropical Diseases, Clinical and Diagnostic Center, Clinical Center, I.M.Sechenov First Moscow State Medical University. Thirty-two patients with echinococcosis 8 with alveococcosis (including 4 inoperable patients), 10 with ascariasis, 10 with toxocariasis, 15 with enterobiasis, and 12 people diagnosed with larva migrans were treated in 2013-2014. The drug's routine doses and dosage regimens were used. Albendazole (Gelmodol, World Medicine, UK) showed a high efficacy with good tolerability, which is highly competitive with that of the drugs manufactured by IPCA Laboratories Ltd., India (such as nemozole). Both medicaments above-mentioned may be successfully used in the treatment of many helminthisms. PMID:26827590

  12. Parasitic colitis.

    Hechenbleikner, Elizabeth M; McQuade, Jennifer A

    2015-06-01

    Over one billion people worldwide harbor intestinal parasites. Parasitic intestinal infections have a predilection for developing countries due to overcrowding and poor sanitation but are also found in developed nations, such as the United States, particularly in immigrants or in the setting of sporadic outbreaks. Although the majority of people are asymptomatically colonized with parasites, the clinical presentation can range from mild abdominal discomfort or diarrhea to serious complications, such as perforation or bleeding. Protozoa and helminths (worms) are the two major classes of intestinal parasites. Protozoal intestinal infections include cryptosporidiosis, cystoisosporiasis, cyclosporiasis, balantidiasis, giardiasis, amebiasis, and Chagas disease, while helminth infections include ascariasis, trichuriasis, strongyloidiasis, enterobiasis, and schistosomiasis. Intestinal parasites are predominantly small intestine pathogens but the large intestine is also frequently involved. This article highlights important aspects of parasitic infections of the colon including epidemiology, transmission, symptoms, and diagnostic methods as well as appropriate medical and surgical treatment. PMID:26034403

  13. X-ray findings of small bowel taeniasis: A clinical and experimental study

    Unlike ascariasis of the small bowel, taeniasis can be detected radiologically with much difficulty because of the basic difference between the morphological features of each helminth. However once the characteristics of tape worms are appreciated and kept in mind, radiological diagnosis is fairly accurately made. In the present study we have reported typical radiological features of the small bowel taeniasis as observed in 6 adults patients seen at the Department of Radiology of St. Mary's Hospital and Holy Family Hospital, Catholic Medical College. Tapering tape-like or ribbon -like radiolucent shadows in distal small bowel appear unique. Compression spot film study of the ileum is most important in revealing such findings. An animal experiment using the swine small intestine and parasitological specimen of evacuated worm of taenia saginata was designed to help understand radiological manifestation in vivo

  14. A paper radioimmunosorbent test (PRIST) for the detection of larva-specific antibodies to Toxocara canis in human sera

    A paper radioimmunosorbent test (PRIST) was shown to be sensitive and reproducible when used with excretory/secretory antigen of Toxocara canis second stage larvae. Whatman No. 50 filter paper (5 mm discs) gave the most consistent and clear results with antigen at a concentration of 100 μg/ml, and could be stored for up to 3 weeks in vacuo at -700C. Antigen coated discs were incubated with test sera at 1 : 10 dilution for 3 h at room temperature (210C), reacted with [125I]anti-human IgG for 1 h and counts determined in a gamma counter. Sera from patients with fascioliasis, taeniasis, schistosomiasis, oxyuriasis, trichinellosis and ancyclostomiasis gave counts similar to cord serum controls. Sera from patients with ascariasis gave counts of up to twice as great as controls, but sera from patients with toxicariasis produced counts of 7,000-13,000, a 4-6 fold increase. (Auth.)

  15. An unusual cause of pancreatitis in a 46-year-old returning traveller.

    Pimenta, Dominic; Dawood, Naghum

    2015-01-01

    A 46-year-old previously fit and well man, travelled to Jhelum, Pakistan for 6 weeks in early 2015. Four weeks after returning to the UK, he developed sudden onset epigastric pain, vomiting and fever. C reactive protein was 232 mg/L and amylase was 2061 U/L. He was treated conservatively as pancreatitis, with peripancreatic streaking and left colic gutter fluid on a CT abdominal scan. He was discharged and later attended the Hospital for Tropical Diseases, after coughing up an 8 cm male ascaris worm. He was treated for acute ascariasis infection, complicated by resolved mild-moderate pancreatitis, a common complication in the developing world but rarely seen among travellers. PMID:26240102

  16. Endoscopic therapy in acute recurrent pancreatitis

    John Baillie

    2008-01-01

    Endoscopic retrograde cholangiopancreatography (ERCP) has evolved from a largely diagnostic to a largely therapeutic rnodality.Cross-sectional imaging,such as computed tomography (CT) and magnetic resonance imaging (MRI),and less invasive endoscopy,especially endoscopic ultrasound (EUS),have largely taken over from ERCP for diagnosis.However,ERCP remains the"first line" therapeutic tool in the management of mechanical causes of acute recurrent pancreatitis,including bile duct stones(choledocholithiasis),ampullary masses (benign and malignant),congenital variants of biliary and pancreatic anatomy (e.g.pancreas divisum,choledochoceles),sphincter of Oddi dysfunction (SOD),pancreatic stones and strictures,and parasitic disorders involving the biliary tree and/or pancreatic duct(e.g Ascariasis,Clonorchiasis).

  17. Biliary obstruction: Helical computed tomography cholangiography evaluation

    Helical computed tomography cholangiography (HCTC) takes advantage of the improvement in the quality of multiplanar and three-dimensional reconstructions resulting from the volumetric acquisition of data achieved with helical computed tomography and the indirect opacification of the bile ducts provided by cholangiographic contrast media. This method was used to evaluate 31 patients with suspected biliary obstruction over a one-year period and the findings were compared with those of direct cholangiography and/or surgery. Biliary opacification was sufficient to allow three-dimensional reconstructions in 90,3% of cases. Sensitivity was 81% for the diagnosis of choledochoolithiasis and 100% for ascariasis, choledochal cysts and anatomic variants of the biliary tree. Our results indicate that HCTC is a valuable alternative as a diagnostic method prior to direct cholangiography. Direct cholangiography should be reserved for those patients who require it as part of a therapeutic procedure

  18. Air in the Wirsung Duct. An Unusual Finding

    Carla Brindisi

    2008-07-01

    Full Text Available Air in the pancreas is frequently reported to be associated with an abscess or a pancreatic fistula but has also been demonstrated in normal pancreatic glands. Air in the Wirsung duct has been reported in three pediatric patients with duodenal obstruction [1], in a child with biliary and pancreatic ascariasis with liver abscesses and a pancreatic pseudocyst [2], in an adult patient with cystic dilatation of the main pancreatic duct limited to the head [3], and in 11 patients with various acute or chronic pancreatic and/or biliary diseases [4]. We report an additional case of air in the Wirsung duct; in the present case, we also observed the presence of air in the duct of Santorini .

  19. Towards an effective control programme of soil-transmitted helminth infections among Orang Asli in rural Malaysia. Part 1: Prevalence and associated key factors

    Nasr Nabil A

    2013-01-01

    Full Text Available Abstract Background Despite the continuous efforts to improve the quality of life of Orang Asli (Aborigines communities, these communities are still plagued with a wide range of health problems including parasitic infections. The first part of this study aimed at determining the prevalence of soil-transmitted helminth (STH infections and identifying their associated factors among rural Orang Asli children. Methods A cross-sectional study was carried out among 484 Orang Asli children aged ≤ 15 years (235 females and 249 males belonging to 215 households from 13 villages in Lipis district, Pahang, Malaysia. Faecal samples were collected and examined by using formalin-ether sedimentation, Kato Katz and Harada Mori techniques. Demographic, socioeconomic, environmental and behavioural information were collected by using a pre-tested questionnaire. Results Overall, 78.1% of the children were found to be infected with one or more STH species. The prevalence of trichuriasis, ascariasis and hookworm infections were 71.7%, 37.4% and 17.6%, respectively. Almost all, three quarters and one fifth of trichuriasis, ascariasis and hookworm infections, respectively, were of moderate-to-heavy intensities. Multiple logistic regression analysis showed that age of ≥ 6 years (school-age, using unsafe water supply as a source for drinking water, absence of a toilet in the house, large family size (≥ 7 members, not washing hands before eating, and not washing hands after defecation were the key factors significantly associated with STH among these children. Conclusion This study reveals an alarmingly high prevalence of STH among Orang Asli children and clearly brings out an urgent need to implement school-based de-worming programmes and other control measures like providing a proper sanitation, as well as a treated drinking water supply and proper health education regarding good personal hygiene practices. Such an integrated control program will help

  20. Neglected tropical diseases outside the tropics.

    Francesca F Norman

    Full Text Available BACKGROUND: The neglected tropical diseases (NTDs cause significant morbidity and mortality worldwide. Due to the growth in international travel and immigration, NTDs may be diagnosed in countries of the western world, but there has been no specific focus in the literature on imported NTDs. METHODS: Retrospective study of a cohort of immigrants and travelers diagnosed with one of the 13 core NTDs at a Tropical Medicine Referral Unit in Spain during the period April 1989-December 2007. Area of origin or travel was recorded and analyzed. RESULTS: There were 6168 patients (2634 immigrants, 3277 travelers and 257 VFR travelers in the cohort. NTDs occurred more frequently in immigrants, followed by VFR travelers and then by other travelers (p<0.001 for trend. The main NTDs diagnosed in immigrants were onchocerciasis (n = 240, 9.1% acquired mainly in sub-Saharan Africa, Chagas disease (n = 95, 3.6% in immigrants from South America, and ascariasis (n = 86, 3.3% found mainly in immigrants from sub-Saharan Africa. Most frequent NTDs in travelers were: schistosomiasis (n = 43, 1.3%, onchocerciasis (n = 17, 0.5% and ascariasis (n = 16, 0.5%, and all were mainly acquired in sub-Saharan Africa. The main NTDs diagnosed in VFR travelers were onchocerciasis (n = 14, 5.4%, and schistosomiasis (n = 2, 0.8%. CONCLUSIONS: The concept of imported NTDs is emerging as these infections acquire a more public profile. Specific issues such as the possibility of non-vectorial transmission outside endemic areas and how some eradication programmes in endemic countries may have an impact even in non-tropical western countries are addressed. Recognising NTDs even outside tropical settings would allow specific prevention and control measures to be implemented and may create unique opportunities for research in future.

  1. Phylogeographical studies of Ascaris spp. based on ribosomal and mitochondrial DNA sequences.

    Serena Cavallero

    Full Text Available BACKGROUND: The taxonomic distinctiveness of Ascaris lumbricoides and A. suum, two of the world's most significant nematodes, still represents a much-debated scientific issue. Previous studies have described two different scenarios in transmission patterns, explained by two hypotheses: (1 separated host-specific transmission cycles in highly endemic regions, (2 a single pool of infection shared by humans and pigs in non-endemic regions. Recently, A. suum has been suggested as an important cause of human ascariasis in endemic areas such as China, where cross-infections and hybridization have also been reported. The main aims of the present study were to investigate the molecular epidemiology of human and pig Ascaris from non-endemic regions and, with reference to existing data, to infer the phylogenetic and phylogeographic relationships among the samples. METHODOLOGY: 151 Ascaris worms from pigs and humans were characterized using PCR-RFLP on nuclear ITS rDNA. Representative geographical sub-samples were also analysed by sequencing a portion of the mitochondrial cox1 gene, to infer the extent of variability at population level. Sequence data were compared to GenBank sequences from endemic and non-endemic regions. PRINCIPAL FINDINGS: No fixed differences between human and pig Ascaris were evident, with the exception of the Slovak population, which displays significant genetic differentiation. The RFLP analysis confirmed pig as a source of human infection in non-endemic regions and as a corridor for the promulgation of hybrid genotypes. Epidemiology and host-affiliation seem not to be relevant in shaping molecular variance. Phylogenetic and phylogeographical analyses described a complex scenario, involving multiple hosts, sporadic contact between forms and an ancestral taxon referable to A. suum. CONCLUSIONS/SIGNIFICANCE: These results suggest the existence of homogenizing gene flow between the two taxa, which appear to be variants of a single

  2. The burden of neglected tropical diseases in Ethiopia, and opportunities for integrated control and elimination

    Deribe Kebede

    2012-10-01

    Full Text Available Abstract Background Neglected tropical diseases (NTDs are a group of chronic parasitic diseases and related conditions that are the most common diseases among the 2·7 billion people globally living on less than US$2 per day. In response to the growing challenge of NTDs, Ethiopia is preparing to launch a NTD Master Plan. The purpose of this review is to underscore the burden of NTDs in Ethiopia, highlight the state of current interventions, and suggest ways forward. Results This review indicates that NTDs are significant public health problems in Ethiopia. From the analysis reported here, Ethiopia stands out for having the largest number of NTD cases following Nigeria and the Democratic Republic of Congo. Ethiopia is estimated to have the highest burden of trachoma, podoconiosis and cutaneous leishmaniasis in sub-Saharan Africa (SSA, the second highest burden in terms of ascariasis, leprosy and visceral leishmaniasis, and the third highest burden of hookworm. Infections such as schistosomiasis, trichuriasis, lymphatic filariasis and rabies are also common. A third of Ethiopians are infected with ascariasis, one quarter is infected with trichuriasis and one in eight Ethiopians lives with hookworm or is infected with trachoma. However, despite these high burdens of infection, the control of most NTDs in Ethiopia is in its infancy. In terms of NTD control achievements, Ethiopia reached the leprosy elimination target of 1 case/10,000 population in 1999. No cases of human African trypanosomiasis have been reported since 1984. Guinea worm eradication is in its final phase. The Onchocerciasis Control Program has been making steady progress since 2001. A national blindness survey was conducted in 2006 and the trachoma program has kicked off in some regions. Lymphatic Filariasis, podoconiosis and rabies mapping are underway. Conclusion Ethiopia bears a significant burden of NTDs compared to other SSA countries. To achieve success in integrated control of

  3. Economic Barriers To Improvement Of Human Health Associated With Wastewater Irrigation In The Mezquital Valley, Mexico

    Yamagata, H.; Sedlak, D. L.

    2008-12-01

    To improve public health, the United Nations' Johannesburg Summit on Sustainable Development in 2002 set Millennium Development Goals (MDGs) of reducing by half the proportion of people without sustainable access to safe drinking water and sanitation by 2015. The Mezquital Valley of Mexico is one of the places suffering serious human health problems such as ascariasis due to agricultural irrigation with untreated wastewater discharged by Mexico City. Despite the existence of serious health problems, wastewater treatment has not been installed due to economic barriers: the agricultural benefit of nutrients in the wastewater and cost of building and operating wastewater treatment plants. To develop solutions to this problem, the human health damage and the benefits of nutrient input were evaluated. The health impact caused by untreated wastewater reuse in the Mezquital Valley was estimated to be about 14 DALYs (disability-adjusted life year) per 100,000, which was 2.8 times higher than the DALYs lost by ascariasis in Mexico in 2002 estimated by WHO. The economic damage of the health impact was evaluated at 77,000 /year using willingness-to-pay (WTP) for reducing DALYs. The value of nutrient inputs (nitrogen and phosphorus) due to reuse of untreated wastewater was evaluated at 33 million /year using fertilizer prices. Therefore, attempts to decrease public health problems associated with reuse in the Mezquital Valley need to address losses of economic benefits associated with nutrients in sewage. In 2007, the Mexican Government announced plans to install wastewater treatment plants in this area. Although nutrient inputs in irrigated water is expected to decrease by 33% due to the wastewater treatment, farmers in the Mezquital Valley would still benefit from improved public health in the community and increases of crop values due to the ability to grow raw-eaten vegetables.

  4. Study on the association between tail lesion score, cold carcass weight and viscera condemnations in slaughter pigs

    Dayane Lemos Teixeira

    2016-03-01

    Full Text Available The aim of this study was to assess the relationship between tail lesions, cold carcass weight and viscera condemnations in an Irish abattoir. The following data were collected at the evisceration point from every 3rd pig slaughtered over 7 days: farm identification, sex, tail lesion score, viscera inspection outcome and cold carcass weight. Tail lesions were scored according to a 5 point scale. Disease lesions responsible for lung (pleurisy, pneumonia and abscess, heart (pericarditis and liver (ascariasis condemnation were recorded based on the decision of the veterinary inspector. Data on 3,143 pigs from 61 batches were available. The relationship between disease lesions, tail lesion score and cold carcass weight was studied at individual carcass level, whereas the relationship between disease lesions and tail lesion score was studied at both carcass and batch level. Tail lesions (score ≥ 1 were found in 72% of the study population, with 2.3% affected by severe tail lesions (scores ≥ 3. Pleurisy (13.7% followed by pneumonia (10.4% showed the highest prevalence, whereas the prevalence of ascariasis showed the greatest variation between batches (0 to 75%. Tail lesion score, pleurisy, pleuropneumonia and pericarditis were associated with reductions in carcass cold weight (P ≤ 0.05 ranging from 3 to 6.6 kg. Tail lesion score was associated with condemnations for pleurisy, pneumonia and pleuropneumonia (P ≤ 0.05 at a batch level. Veterinary inspector shift was associated with condemnations for pneumonia, pleuropneumonia and pericarditis (P ≤ 0.05 at a carcass level and with pneumonia at a batch level. Sex was not associated with viscera condemnations but males were more likely to be affected by tail lesions. The relationship between overall tail lesion score and the lung diseases at batch level supports the relationship between poor health and poor welfare of pigs on farms. The inclusion of tail lesion scores at post mortem meat

  5. Study on the Association between Tail Lesion Score, Cold Carcass Weight, and Viscera Condemnations in Slaughter Pigs.

    Teixeira, Dayane Lemos; Harley, Sarah; Hanlon, Alison; O'Connell, Niamh Elizabeth; More, Simon John; Manzanilla, Edgar Garcia; Boyle, Laura Ann

    2016-01-01

    The aim of this study was to assess the relationship between tail lesions, cold carcass weight, and viscera condemnations in an Irish abattoir. The following data were collected at the evisceration point from every third pig slaughtered over 7 days: farm identification, sex, tail lesion score, viscera inspection outcome, and cold carcass weight. Tail lesions were scored according to a 5-point scale. Disease lesions responsible for lung (pleurisy, pneumonia, and abscess), heart (pericarditis), and liver (ascariasis) condemnation were recorded based on the decision of the veterinary inspector (VI). Data on 3,143 pigs from 61 batches were available. The relationship between disease lesions, tail lesion score, and cold carcass weight was studied at individual carcass level, while the relationship between disease lesions and tail lesion score was studied at both carcass and batch level. Tail lesions (score ≥1) were found in 72% of the study population, with 2.3% affected by severe tail lesions (scores ≥3). Pleurisy (13.7%) followed by pneumonia (10.4%) showed the highest prevalence, whereas the prevalence of ascariasis showed the greatest variation between batches (0-75%). Tail lesion score, pleurisy, pleuropneumonia, and pericarditis were associated with reductions in carcass cold weight (P ≤ 0.05) ranging from 3 to 6.6 kg. Tail lesion score was associated with condemnations for pleurisy, pneumonia, and pleuropneumonia (P ≤ 0.05) at a batch level. VI shift was associated with condemnations for pneumonia, pleuropneumonia, and pericarditis (P ≤ 0.05) at a carcass level and with pneumonia at a batch level. Sex was not associated with viscera condemnations but males were more likely to be affected by tail lesions. The relationship between overall tail lesion score and the lung diseases at batch level supports the relationship between poor health and poor welfare of pigs on farms. The inclusion of tail lesion scores at post-mortem meat inspection

  6. Antihelmínticos como factor de riesgo en la obstrucción intestinal por Ascaris lumbricoides en niños Anthelmintics as a risk factor of the intestinal obstruction by Ascaris lumbricoides in children

    Oscar Vásquez Tsuji

    2000-01-01

    Full Text Available In a retrospective study the authors analyzed the clinical records of 199 children ages one month to 16 years hospitalized, with the diagnosis of intestinal ascariasis, in the Instituto Nacional de Pediatria of Mexico from 1984 to 1999. The purpose of the study was to evaluate the use of anthelmintics drugs as a risk factor of intestinal obstruction by A. lumbricoides. Two groups were made for the study: Group A (n=66 of children who presented intestinal obstruction, Group B (n=133 children with no complications. A comparative analysis of clinical data of both groups was made by means of chi square with Yates correction and a stratified analysis by means of chi square. Possible confusing elements were overcrowding, age and the use of antiparasitic drugs. The calculus of risk factors for intestinal obstruction by A. lumbricoides was done by means of contingency tables of 2 x 2 and odds ratio with an IC of 95%. The significant risk factors were included in a model of logistics regression with an impact variable consting in the presence or absence of intestinal obstruction in order to establish a multivariate model of predictive risk a level of significance of p < 0.05. Twenty seven patients (40.90% in group A (n=66 were given anthelmintics medications prior to the intestinal obstruction: mebendazol, 14 (51-85%; two, albedazol (7.40%; eigth, a non-specifed anthelmintic (29-62%. In addition, an anthelmintic medication without a specified time of ingestion: two with mebendazol and one with piperazine (11.3%. In the case of mebendazol, the drug most frequently associated with intestinal obstruction, seven patients received it on the same day of the obstruction; five patients received it between one and seven days prior to the obstruction; two received it seven days prior to the complication. In the control group, only 7% had taken the anthelmintic one to seven days before the diagnosis of uncomplicated intestinal ascariasis diagnosis was made. With

  7. Recall of intestinal helminthiasis by HIV-infected South Africans and avoidance of possible misinterpretation of egg excretion in worm/HIV co-infection analyses

    van der Merwe Lize

    2006-05-01

    Full Text Available Abstract Background Ascariasis and HIV/AIDS are often co-endemic under conditions of poverty in South Africa; and discordant immune responses to the respective infections could theoretically be affecting the epidemic of HIV/AIDS in various ways. It is well-known that sensitisation to helminthic antigens can aggravate or ameliorate several non-helminthic diseases and impair immunisation against cholera, tetanus and tuberculosis. The human genotype can influence immune responses to Ascaris strongly. With these factors in mind, we have started to document the extent of long-term exposure to Ascaris and other helminths in a community where HIV/AIDS is highly prevalent. In more advanced studies, objectives are to analyse relevant immunological variables (e.g. cytokine activity and immunoglobulin levels. We postulate that when Ascaris is hyperendemic, analysis of possible consequences of co-infection by HIV cannot be based primarily on excretion vs non-excretion of eggs. Methods Recall of worms seen in faeces was documented in relation to the age of adult volunteers who were either seropositive (n = 170 or seronegative (n = 65 for HIV. Reasons for HIV testing, deworming treatments used or not used, date and place of birth, and duration of residence in Cape Town, were recorded. Confidence intervals were calculated both for group percentages and the inter-group differences, and were used to make statistical comparisons. Results In both groups, more than 70% of participants were aware of having passed worms, often both when a child and as an adult. Most of the descriptions fitted Ascaris. Evidence for significantly prolonged exposure to helminthic infection in HIV-positives was supported by more recall of deworming treatment in this group (p Conclusion There was a long-term history of ascariasis (and probably other helminthic infections in both of the groups that were studied. In women in the same community, and in children living where housing and

  8. The nutritional impacts of soil-transmitted helminths infections among Orang Asli schoolchildren in rural Malaysia

    Ahmed Abdulhamid

    2012-06-01

    Full Text Available Abstract Background Soil-transmitted helminths (STH infections, anaemia and malnutrition are major public health problems in school-age children in developing countries. This study was conducted on 289 Orang Asli (aboriginal schoolchildren in order to assess the current prevalence and predictors of anaemia and malnutrition, as well as the nutritional impacts of STH infections among these children. Methods A cross-sectional study was combined with a longitudinal follow-up three months after treatment with anthelminthic drugs. Blood samples were collected from the children to measure haemoglobin (Hb level. Anthropometric and socioeconomic data were also collected and the children were screened for STH. Results The baseline findings revealed that the prevalence of anaemia, significant stunting, underweight and wasting among the children were 41.0%, 28.0%, 29.2% and 12.5%, respectively. Overall, the prevalence of trichuriasis, ascariasis and hookworm infections were 84.6%, 47.6% and 3.9%, respectively. Haemoglobin level was significantly lower among the moderate-to-heavy infected children compared to the negative-to-light infected children. Age Conclusion STH infections, anaemia and malnutrition are still prevalent and a matter of public health concern in Orang Asli communities in Malaysia. Sustainable deworming programme at school and community levels among these populations will help to improve their health and nutritional status.

  9. Identifying gaps in research prioritization: The global burden of neglected tropical diseases as reflected in the Cochrane database of systematic reviews

    Bhaumik, Soumyadeep; Karimkhani, Chante; Czaja, Christopher A.; Williams, Hywel C.; Rani, Monica; Nasser, Mona; Boyers, Lindsay N.; Dmitruk, Sergei; Dellavalle, Robert P.

    2015-01-01

    Background: Neglected tropical diseases (NTDs) impact disadvantaged populations in resource-scarce settings. Availability of synthesized evidence is paramount to end this disparity. The aim of the study was to determine whether NTD systematic reviews or protocols in the Cochrane Database of Systematic Reviews (CDSR) reflect disease burden. Methods: Two authors independently searched the CDSR for reviews/protocols regarding the NTDs diseases. Each review or protocol was classified to a single NTD category. Any discrepancy was solved by consensus with third author. NTD systematic review or protocol from CDSR were matched with disability-adjusted life year (DALY) metrics from the Global Burden of Disease 2010 Study. Spearman's rank correlation coefficient and associated P values were used to assess for correlation between the number of systematic reviews and protocols and the %2010 DALY associated with each NTD. Results: Overall, there was poor correlation between CDSR representation and DALYs. Yellow fever, echinococcus, onchocerciasis, and schistosomiasis representation was well-aligned with DALY. Leprosy, trachoma, dengue, leishmaniasis, and Chagas disease representation was greater, while cysticercosis, human African trypanosomiasis, ascariasis, lymphatic filariasis, and hookworm representation was lower than DALY. Three of the 18 NTDs had reviews/protocols of diagnostic test accuracy. Conclusions: Our results indicate the need for increased prioritization of systematic reviews on NTDs, particularly diagnostic test accuracy reviews. PMID:26985407

  10. Therapeutic efficacy of different brands of albendazole against soil transmitted helminths among students of Mendera Elementary School, Jimma, Southwest Ethiopia

    Tefera, Ephrem; Belay, Tariku; Mekonnen, Seleshi Kebede; Zeynudin, Ahmed; Belachew, Tefera

    2015-01-01

    Introduction Different brands Albendazole are commercially available and the efficacious brand/s is/are required for effective control of STHs infection. Thus, this study is aimed at determining the therapeutic efficacy of different brands of albendazole against soil transmitted helminths among school children of Jimma town. Methods A cross sectional survey for prevalence of geohelminths and a randomized trial for efficacy study of different brands of albendazole was conducted among students Mendera Elementary School from March 29 to April 29, 2010. Positive subjects were randomized into three treatment arms using lottery method. The collected stool samples were examined by the McMaster method. CRs were calculated using SPSS windows version 16 and ERRs were calculated using appropriate formula. Results Of the 715 school children who had their stools examined, 326 were positive for STHs with a prevalence rate of 45.6%. The cure rates (CR) for A. lumbricoides, T. trichiura and Hookworm were 99.4, 59.9 and 93.7%, respectively. Similarly, the egg reduction rates (ERR) were 97, 99.9 and 99.9% respectively. A statistical significant mean STH egg count difference were observed between pre and post-intervention study (p 0.05). Conclusion All the three brands of Albendazole tested regardless of the brand type were therapeutically efficacious for Ascariasis, Trichuriasis and Hookworm infections irrespective of the infection status whether it was single or multiple. PMID:26958115

  11. Investigation of Anti-Toxocara Antibodies in Epileptic Patients and Comparison of Two Methods: ELISA and Western Blotting

    Mohammad Zibaei

    2013-01-01

    Full Text Available The relationship between Toxocara infection and epilepsy was previously demonstrated by several case-control studies and case reports. These previous studies were often based on the enzyme-linked immunosorbent assay (ELISA using Toxocara excretory-secretory antigens, which are not specific due to cross-reactivity with other parasitic infections such as ascariasis, trichuriasis, and anisakiasis. An immunoblot analysis is highly specific and can detect low levels of Toxocara antibodies. Therefore, this assay may be useful in the identification of toxocariasis in epileptic patients. We examined patients who had epilepsy and healthy subjects for seropositivity for Toxocara infection by ELISA and Western blotting. Out of 85 epileptic patients, 10 (11.8% and 3 (3.5% persons exhibited Toxocara immunoglobulin G (IgG antibodies responses by ELISA and by both techniques, respectively. Moreover, in the healthy group (, 3 (3.5% persons were positive by ELISA, but none was detected by Western blotting. This study indicates that Toxocara infection is a risk factor for epilepsy in Iran. These findings strongly suggest the need to perform Western blotting immunodiagnosis, as well as the ELISA using Toxocara excretory-secretory antigens, to improve diagnosis of human toxocariasis in patients with epilepsy.

  12. YI Xianrong’s experience in treating anorectal diseases%衣先荣教授诊治肛肠病经验

    马一铭; 张盈

    2015-01-01

    Professor YI Xianrong thinks that the treatment of anorectal diseases should be combining the theory of Em-peror’s Canon of Medicine,the syndrome types are mainly of anorectal dis ease syndrome of intestine - dryness fluid deficiency of Constipation,syndrome of deficiency for spleen and stomach qi of diarrhoea,syndrome of damp heat sta-sis of periappendicular abscess,syndrome of intermingled heat and cold of syncope due to ascariasis. He advocated use nourishing yin and clearing heat,moistening dryness for relaxing bowels,strengthening spleen and nourishing qi and excreting dampness to stop Diarrhea,clearing heat and removing toxicity,eliminating perianal abscess,reducing heat of Shangjiao and dispelling cold of Xiajiao,calming ascaris to relieve pain for diagnosis and treatment of anorectal disease.%衣先荣教授认为,肛肠病诊治时应结合《内经》理论,从肠燥津亏秘结证、脾胃气虚泄泻证、湿热瘀滞肠痈证、寒热错杂蛔厥证加以分型,治疗上采用滋阴清热、润燥通便,健脾益气、渗湿止泻,清热解毒、排脓消痈,清上温下、安蛔止痛等法。

  13. Albendazole, a broad-spectrum anthelmintic, in the treatment of intestinal nematode and cestode infection: a multicenter study in 480 patients.

    Jagota, S C

    1986-01-01

    The anthelmintic activity of and patient tolerance to albendazole, a broad-spectrum anthelmintic, were studied in a multicenter trial involving 480 patients ranging in age from 2 to 60 years. The patients had single or mixed infections caused by pinworms, roundworms, hookworms, whipworms, threadworms, or tapeworms. The stools were examined by the direct method, and ova were counted by means of the Kato-Katz technique. A Graham-Scotch test was also done in patients infected with Enterobius vermicularis. Most patients received a single 400-mg dose of albendazole; adults were given two tablets, and children were given a 2% suspension. All patients with Hymenolepis nana and about half of those with Taenia infections were treated for three successive days. Patients were carefully evaluated before and after treatment to assess the efficacy and safety of the drug. After a single dose of albendazole, the cure rate was 95.3% in ascariasis, 92.2% in ancylostomiasis, 90.5% in trichuriasis, 64.9% in taeniasis, and 100% in enterobiasis. Among patients receiving 400 mg of albendazole for three days, the cure rate was 63.4% in hymenolepiasis and 86.1% in taeniasis. The drug was well tolerated, and no significant side effects were reported. PMID:3516398

  14. Albendazole in the treatment of intestinal helminthiasis in children.

    Prasad, R; Mathur, P P; Taneja, V K; Jagota, S C

    1985-01-01

    One hundred sixteen children between 2 and 15 years of age entered a clinical trial of albendazole after examination of their stools revealed ova of one or more intestinal helminths. The drug was administered as a single 400-mg dose (20 ml of 2% suspension) to all the patients except those having Hymenolepis nana infection, who received treatment for three consecutive days. The stools were reexamined on days 7 and 14 posttreatment and after three months for Taenia infections. Patients were considered cured if all parasitological examinations of the feces were negative after treatment. After a single oral dose, albendazole was highly effective in ascariasis (91.9%), ancylostomiasis caused by Ancylostoma duodenale (87.2%), and H nana infection (71.4%). The drug was well tolerated, and no abnormalities were observed in hematological or blood chemistry values. Since the drug is safe and effective as a single-dose treatment of common helminthic infections, it should be considered for mass therapy in the community. PMID:3986860

  15. La parasitología y la entomología en la narrativa latinoamericana del siglo XX Parasitology and entomology in the 20th century Latin American narrative

    Hugo Schenone

    2000-07-01

    Full Text Available In the present reviev of twelve pieces produced by distinguished 20th century Latin American writers Jorge Luis Borges from Argentina, Jorge Amado and João Ubaldo Ribeiro from Brazil, José Donoso from Chile, Gabriel García Márquez from Colombia, Alejo Carpentier from Cuba, Miguel Angel Asturias from Guatemala, Octavio Paz from Mexico, Mario Vargas Llosa from Perú, Horacio Quiroga and Mario Benedetti from Uruguay and Arturo Uslar-Pietri from Venezuela ­ paragraphs or parts of paragraphs in which parasitological or entomological situations of the most varied hues are referred to or described, have been extracted in a selective form. Sometimes in these descriptions appear, local or regional expressions, without ignoring colorful folkloric representations. For a easier interpretation these or part of these paragraph sentences have been arranged by thematic similarities. In a varied and kaleidoscopic vision, it will be possible to find protozooses (malaria, Chagas disease, leishmaniasis, amibiasis, helminthiases (ascariasis, hydatidosis, trichinosis, schistosomiasis, cysticercosis, onchocerciasis, parasitoses produced by arthropods (pediculosis, scabies, tungiasis, myiasis, passing progressivelly to hemaphagous arthropods (mosquitoes, gnats, horse flies, bedbugs, ticks, venomous arthropods (Latrodectus spiders, scorpions, wasps, bees, mechanical vectors (flies and cockroaches, culminating with a conjuction of bucolic arthropods (butterflies, crickets, grasshoppers cicadas, ants, centipedes, beetles, glowworms, dragonflies.

  16. Determination of cholesterol in human biliary calculus by TLC scanning

    Yin Kang Yang; Kai Xiong Qiu; Yu Zhu Zhan; Er Yi Zhan; Hai Ming Yang; Ping Zheng

    2000-01-01

    AIM To study the physico-chemical properties of biliary calculus and the relationship between the calculusformation and the phase change of liquid crystal, providing the best evidence for the biliary calculusprevention and treatment.METHODS The cholesterol contents in thirty one cases of biliary calculus in Kunming were determined bydouble-wave-length TLC scanning with high efficiency silica gel films.RESULTS Under magnifiers, the granular biliary calculus from 31 patients were classified according totheir section structures and colours, as cholesterol cholelith, 25 cases; bilirubin cholelith, 4 cases andcompound cholelith, 2 cases. By TLC scanning, it was found that the content of cholesterol in human biliarycalculus was 71%- 100%, about 80% cholesterol bilestones whose cholesterol content was more than 90%being pure cholesterol bilestones.CONCLUSION Cholesterol bilestone is the main human biliary calculus in Kunming, which was inaccordance with X-ray analysis. Compared with the related reports, it is proved that the proportion ofcholesterol bilestones to biliary calculus is increasing because of the improved life standard and the decreaseof bilirubin bilestones resulted from bile duct ascariasis or bacteria infection in China since 90s, and that theincrease of cholesterol in-take leads to the increase of cholesterol metabolism disorder

  17. ECENT ADVANCES IN KNOWLEDGE OF SOIL-TRANSMITTED HELMINTHS

    Paul C. Beaver

    1975-07-01

    Full Text Available New observations in recent years have accented differences between the two common hookworms, Ancylostoma duodenale and Necator americanus,"nwith respect to modes of transmision and pathogenicity, and have established Ancylostoma ceylanicum as a species distinct from A. braziliense. Transmammary and paratenic transmission are now considered to be natural modes of infection in Ancylostoma caninum and possibly 111 other Ancylostoma species including A. duodenale, but not in Necator. The question of relative blood losses from laceration hemorrhage and blood-sucking in hookworm anemia is unresolved. The prevalence of Loeffler's syndrome in pulmonary ascariasis appears to be greatest in areas where transmission is sharply seasonal. Recent studies have failed to confirm reports of blood-sucking by Trichuris. Milk-borne transmission from mother to the newborn has been demonstrated for numberous species of Strongyloides not including S. stercoralis. Zoonotic soil-transmitted helminths 0; dogs and cats have become recognized as frequently causing visceral larva migrans and occasionally blindness in most parts of the world. Two major advances were made in diagnostic techniques - the Harada-Mori test-tube hookworm culture for species diagnosis and the Kato cellophane-covered thick fecal film ror ranid and quantitative diagnosis of intestinal helminth infections.

  18. Geohelminth Infections and Nutritional Status of Preschool Aged Children in a Periurban Settlement of Ogun State

    O. O. Omitola

    2016-01-01

    Full Text Available This study assessed the geohelminth and nutritional status of preschoolers in a periurban community of Ogun state. Fresh stool specimens were collected for laboratory analysis, processed using ether concentration method, and examined under the microscope for geohelminth ova. Demographic characteristics and daily nutrient intake of children were subjectively assessed during an interview session with parents, following anthropometric data collection. Data obtained were analysed using a statistical software for Windows. Nutritional indicators such as underweight, stunting, and wasting were computed from anthropometric data. Results showed an overall prevalence of 39.2% and 12.4% for Ascariasis and Hookworm infection, respectively, with no significant difference (P>0.05 between the sexes. Prevalence of nutritional indicators was 52.6%, 35.1%, 34.0%, and 9.3% for underweight, stunting, wasting, and thinness conditions, respectively. A good proportion of the malnourished preschoolers were free of Ascaris infection but infected with Hookworm parasite. The adverse effect of geohelminth infection cannot still be ignored in impaired growth, reduced survival, poor development, and cognitive performance of preschoolers. Therefore promotion of adequate health education program on measures of preventing geohelminth infections is needed.

  19. A review of pig pathology in Tanzania.

    Wilson, Richard Trevor; Swai, Emmanuel

    2013-08-01

    The approximately 1.58 million pigs in Tanzania represent 3.7% of the national population of quadruped meat-producing animals. Pigs are kept mainly by small producers who own 99.5% of the national stock in units that average 3.04 animals (range 2-48). Government policy has had little practical application. African swine fever, foot-and-mouth disease and Cysticercosis are important diseases. The first two are notifiable diseases under Tanzania legislation; the last has widespread distribution and relevance as a major zoonosis. Ascariasis (Ascaris suum), hydatidosis (Echinococcus granulosus), leptospirosis (Leptospira interrogans) and thermophilic Campylobacter are other zoonoses associated with pigs. Gastrointestinal helminths and external parasites, especially Sarcoptes scabiei, are common. Risk factors associated with cysticercosis for humans working with pigs or eating their meat include the free-range or semi-confined management systems, the use of rivers or ponds as a source of water, lack of household sanitation, informal home slaughter, pork not being inspected at slaughter slabs and undercooked and barbecued meat. Pigs are a minor component of Tanzania's livestock sector but there is potential for increasing their contribution to human welfare. Prospects are enhanced by the shorter life cycle, greater number of young produced per year and the possibility of producing high-quality animal protein at a lower cost than meat produced by cattle and small ruminants. PMID:23733144

  20. REVIEW ON IMPORTANT HELMINTHIC DISEASES IN ANIMAL IN INDONESIA

    I.G. P. Suweta

    2012-09-01

    Full Text Available Helminthic diseases are widely spread throughout the world. In Indonesia, the cases in animals are primarily associated with the condition of the field, although the intensity of the infestations are also affected by various factors inside the body of the host. In general, the tropical and humid conditions in Indonesia, optimally support the development and spreading of the parasites, so that the prevalence of the infestations are usually high except in the very dry areas. In Indonesia, important helminthic diseases found in livestock are mostly caused by nematodes and trematodes, and there is a lack of information regarding cestode infestations, except infestation by immature stages of the worm such as cysticercosis in ruminants and swine. On the other hand, dogs and cats are usually infested by cestodes and nematodes. Here, the negative influence of helminthic infestation on live stock is mostiy shown by failure of growth, decrease of body weight and body resistance, damage of organs infested by the parasites, but it is not rare that the disease cause death of the infested animals such as haemonchiasis in sheep, ascariasis in young swine and calves, etc. The integrated system of farming combined with periodic anthelminthic treatments were favourable in the effort of controlling the disease.

  1. Ascaridíase das vias urinárias: um caso de penetração de Ascaris lumbricoides através do rim

    Mario Caymmi Gomes

    1977-10-01

    Full Text Available Uma criança de 2 anos com desnutrição grave e infestação intestinal maciça por Ascaris lumbricoides, apresentou como complicação, documentada em necrópsia, a migração de vermes adultos para a cavidade peritonial e penetração aberrante de dois parasitos através do rim esquerdo. Os Ascaris ficaram alojados no sistema pielo-ureteral, determinando grave infecção purulenta e obstrução ureteral. Esta complicação demonstra a capacidade agressiva de vermes erráticos na cavidade peritonial, com possibilidade de perfurar mesmo uma víscera sólida. São comentados os fatores que facilitaram a migração dos vermes por aqueles órgãos.The author reports an autopsy case of a two year old child with massive intestinal ascariasis and malnutrition, presenting the migration of two adult Ascaris lumbricoides through the left kidney into the pyelo-ureteral system. As a result she developed acute pyelonephritis and ureteral obstruction. Previously the worms left the intestine into the peritoneal cavity (lesser sac through a duodenal cleft. Factors contributing to the migration of the roundworms by those pathways are discussed.

  2. Soil-transmitted helminth infections and correlated risk factors in preschool and school-aged children in rural Southwest China.

    Xiaobing Wang

    Full Text Available We conducted a survey of 1707 children in 141 impoverished rural areas of Guizhou and Sichuan Provinces in Southwest China. Kato-Katz smear testing of stool samples elucidated the prevalence of ascariasis, trichuriasis and hookworm infections in pre-school and school aged children. Demographic, hygiene, household and anthropometric data were collected to better understand risks for infection in this population. 21.2 percent of pre-school children and 22.9 percent of school aged children were infected with at least one of the three types of STH. In Guizhou, 33.9 percent of pre-school children were infected, as were 40.1 percent of school aged children. In Sichuan, these numbers were 9.7 percent and 6.6 percent, respectively. Number of siblings, maternal education, consumption of uncooked meat, consumption of unboiled water, and livestock ownership all correlated significantly with STH infection. Through decomposition analysis, we determined that these correlates made up 26.7 percent of the difference in STH infection between the two provinces. Multivariate analysis showed that STH infection is associated with significantly lower weight-for-age and height-for-age z-scores; moreover, older children infected with STHs lag further behind on the international growth scales than younger children.

  3. Health status of the prisoners in a central jail of south India

    Sunil D Kumar

    2013-01-01

    Full Text Available Background: Health care in prisons is one of the neglected health areas in our country. Looking into the health problems of prisons will show us a way for the approach in providing the heath care for prisoners. Objectives: To assess the health status of convicted inmates of prison and to study their sociodemographic profile. Materials and Methods: A cross-sectional study was conducted among the inmates of central prison over a period of 1 year. Study population comprised of 300 convicted life-term prisoners. The inmates were interviewed using predesigned and pretested proforma. Sociodemographic data were analyzed by frequencies and percentages along with 95% confidence interval using statistical package SPSS18. Results: In health status, 29 (9.6% inmates suffered from acute upper respiratory tract infections and 15 (5% from acute lower respiratory tract infections. A total of 54 (18% inmates had ascariasis. Diseases of musculoskeletal system and connective tissue contributed to 26 (8.7% of inmates. A total of 252 (84% prisoners had anemia. In sociodemographic profile, it was found that rural people, unmarried, illiterates, lower socioeconomic status people were more likely to have committed the crime resulting in the conviction for life. Conclusions: As there is an increase in number of prisoners and morbidities among them, there is an urgent need for prison health care services in developing countries like India and provide training to the health care providers to manage the commonly existing health problems among prisoners in the prisons.

  4. African Program for Onchocerciasis Control 1995-2010: Impact of Annual Ivermectin Mass Treatment on Off-Target Infectious Diseases.

    Stanimira P Krotneva

    Full Text Available Since its initiation in 1995, the African Program for Onchocerciasis Control (APOC has had a substantial impact on the prevalence and burden of onchocerciasis through annual ivermectin mass treatment. Ivermectin is a broad-spectrum anti-parasitic agent that also has an impact on other co-endemic parasitic infections. In this study, we roughly assessed the additional impact of APOC activities on the burden of the most important off-target infections: soil-transmitted helminthiases (STH; ascariasis, trichuriasis, hookworm, and strongyloidiasis, lymphatic filariasis (LF, and scabies. Based on a literature review, we formulated assumptions about the impact of ivermectin treatment on the disease burden of these off-target infections. Using data on the number of ivermectin treatments in APOC regions and the latest estimates of the burden of disease, we then calculated the impact of APOC activities on off-target infections in terms of disability-adjusted life years (DALYs averted. We conservatively estimated that between 1995 and 2010, annual ivermectin mass treatment has cumulatively averted about 500 thousand DALYs from co-endemic STH infections, LF, and scabies. This impact comprised approximately an additional 5.5% relative to the total burden averted from onchocerciasis (8.9 million DALYs and indicates that the overall cost-effectiveness of APOC is even higher than previously reported.

  5. Intestinal Helminth Infections in Pregnant Women Attending Antenatal Clinic at Kitale District Hospital, Kenya

    A. W. Wekesa

    2014-01-01

    Full Text Available Intestinal helminth infections during pregnancy are associated with adverse outcomes including low birth weight and prenatal mortality. The infections are a major public health problem in developing countries. A hospital based survey was undertaken for six months to determine the infection prevalence, intensity, and risk factors. The study involved expectant women attending antenatal clinic. Stool samples were screened microscopically for helminth ova using Kato Katz technique. Information on risk factors was collected using semistructured questionnaire and analyzed using SPSS. Epidemiological data was analysed using descriptive statistics and multivariate analysis. The overall prevalence of infection was 21 (13.8%. Ascariasis was the most prevalent 10 (6.5%, hookworm infection was 6 (3.9%, and trichuriasis was 2 (1.3%. Pregnant women aged below 29 years (OR = 3.63, CI = 0.87–11.75 and those with primary level of education (OR = 3.21, CI = 0.88–11.75 were at a higher risk of infection compared to those aged ≥ 29 years with secondary level of education. Hand washing was significantly associated with reduced likelihood of infection (OR = 0.18, 95% CI = 0.06–0.57. It was concluded that intestinal helminth infections were prevalent among pregnant women. We recommended that all expectant women visiting antenatal clinics be screened for intestinal helminth infections and positive cases be advised to seek treatment.

  6. Percutaneous transhepatic cholangiographic evaluation of obstructive jaundice

    Kang, Hee Tae; Kim, Hong Soo; Kim, Jong Deok; Rhee, Hak Song [Presbyterian Medical Center, Jeonju (Korea, Republic of)

    1983-12-15

    PTC is the single most valuable diagnostic method available to evaluate the size, shape and site of the causes of obstructive jaundice among various radiological procedures. The authors reviewed and radiologically classified the PTC films of 203 cases of obstructive jaundice from July, 1977 to June, 1983 at Presbyterian Medical Center, Jeonju confirmed clinically, operatively and pathologically. The results are as follows; 1. The most common cause of obstructive jaundice was bile duct stone (64/203: 31.53%) and the other causes were bile duct cancer (43/203: 21.18%), pancreas cancer (41/203: 20.19%), biliary ascariasis and/or clonorchiasis (20/203: 9.8%), ampulla and duodenal cancer (7/203: 3.45%), fibrotic stenosis of sphincter of Oddi (6/203: 2.96%) etc. in the order. Of these primary involvement with cancer was more frequent (91/203: 44.33%) than stone. 3. The average maximal diameter of extrahepatic bile duct just proximal to the site of obstruction or stenosis by stones or by cancers was nearly equal (2.36 cm : 2.38 cm). 4. Cancers caused complete bile duct obstruction in about 75% (68/91) of cases and also were associated with intrahepatic duct dilatation about 92% (84/91) of cases. But in contrast biliary calculi showed good drainage of contrast medium in 75% (48/64) of cases and 92% (59/64) showed normal diameter.

  7. Our experience with peroral application of ivermektin in therapy of swine endoparasitosis

    Pavlović Ivan

    2002-01-01

    Full Text Available Endoparasitic infections present a frequent health problem among swine maintained on farms, with ascariasis and esophagostamosis being the most frequent diseases. There are several valid methods in curbing parasites in swine - peroral application of antiparasitics and their subcutaneous application. Ivermektin is an antiparasitic with a wide range of effects which is successfully used in curbing ecto and endoparasites in swine and other animals. Ivermektin has so far primarily been applied subcutaneously which required considerable efforts and the engagement of numerous staff in therapy of large agglomerations of frarm animals. In recent years Ivermektin has appeared in powder form that is mixed in feed which largely facilitates therapy and the prevention of ecto and endoparasitoses in farm animals. In order to examine the efficiency of the peroral application of Ivermektin in treating endoparasitic infections, our paper presents the curbing of acradosis and esophagostamosis in farm swine using peroral application of Ivermektin (Ivermektin-P, Hemovet, Vršac. Four control examinations after therapy did not reveal any parasite infections, which is evidence that Ivermektin is absolutely efficient when applied perorally. On the grounds of the obtained results, we are of the opinion that the peroral application of Ivermektin is a successful therapy of endoparasitic infections in swine, which is not in any way less efficient than its subcutaneous application. The peroral application of Ivermektin largely facilitates therapy and the prevention of parasitic infections on farms with large agglomerations of animals.

  8. Zoonotic helminths affecting the human eye

    Eberhard Mark L

    2011-03-01

    Full Text Available Abstract Nowaday, zoonoses are an important cause of human parasitic diseases worldwide and a major threat to the socio-economic development, mainly in developing countries. Importantly, zoonotic helminths that affect human eyes (HIE may cause blindness with severe socio-economic consequences to human communities. These infections include nematodes, cestodes and trematodes, which may be transmitted by vectors (dirofilariasis, onchocerciasis, thelaziasis, food consumption (sparganosis, trichinellosis and those acquired indirectly from the environment (ascariasis, echinococcosis, fascioliasis. Adult and/or larval stages of HIE may localize into human ocular tissues externally (i.e., lachrymal glands, eyelids, conjunctival sacs or into the ocular globe (i.e., intravitreous retina, anterior and or posterior chamber causing symptoms due to the parasitic localization in the eyes or to the immune reaction they elicit in the host. Unfortunately, data on HIE are scant and mostly limited to case reports from different countries. The biology and epidemiology of the most frequently reported HIE are discussed as well as clinical description of the diseases, diagnostic considerations and video clips on their presentation and surgical treatment. Homines amplius oculis, quam auribus credunt Seneca Ep 6,5 Men believe their eyes more than their ears

  9. Evaluation of an enzyme-linked immunoelectrotransfer blot test for the confirmatory serodiagnosis of human toxocariasis

    William H Roldán

    2009-05-01

    Full Text Available To improve the serodiagnosis of human toxocariasis, a sensitive and specific enzyme-linked immunoelectrotransfer blot (EITB-IgG test was developed and evaluated using Toxocara canislarvae excretory-secretory antigens for detecting anti-Toxocara IgG antibodies. The EITB-IgG profile of toxocariasis was characterized by comparing 27 sera from patients with toxocariasis, 110 sera from healthy subjects and 186 sera from patients with other helminth diseases (ascariasis, ancylostomiasis, trichuriasis, enterobiasis, strongyloidiasis, hymenolepiasis, diphyllobothriasis, taeniasis, cysticercosis, hydatidosis and fascioliasis. Antigenic bands of 24, 28, 30, 35, 56, 117, 136 and 152 kDa were predominantly recognized in sera from all patients with toxocariasis. However, only bands of 24-35 kDa were highly specific for Toxocara infection (98.3%, whereas other antigenic bands observed displayed cross-reactivity. Additionally, when the results of the EITB-IgG test were compared to those of the ELISA-IgG test, a 100% concordance was observed for positive results in human toxocariasis cases. The concordance for negative results between the two tests for healthy subjects and patients with other helminth diseases were 96.3% and 53.7%, respectively, showing that the EITB-IgG test has a higher specificity than ELISA. In conclusion, the EITB-IgG test is a very useful tool to confirm the serological diagnosis of human toxocariasis.

  10. Percutaneous transhepatic cholangiography using fine needle

    Chung, Kyoo Byung; Kim, Yun Hwan; Lee, Nam Joon; Suh, Won Hyuck [College of Medicine, Korea University, Seoul (Korea, Republic of)

    1980-12-15

    In recent years, percutaneous transhepatic cholangiography (PTC) using fine needle has become widely employed as the procedure of choice for direct opacification of the biliary trees because of its high success rate, easy performance and relative low complication rate. Authors present the clinical and PTC findings of experienced cases during last four years, from May 1976 to June 1980, at the Department of Radiology, Korea University Hospital. We tried to study of PTC in 44 cases, 32 males and 12 females, and succeeded in visualization of bile ducts in 41 cases, but the other three cases were failed to visualize the bile ducts. Final confirmative diagnosis was achieved in 29 cases by operation, laparoscopy and other clinical methods. The PTC diagnosis was correct in 24 of 29 cases, and the others were incorrect. The 29 final diagnosis was including 13 cases of biliary stones, 6 cases of biliary cancer, 3 cases of pancreatic cancer, 3 cases of clonorchiasis, one case of CBD ascariasis and 3 cases of others. Incorrect PTC diagnosis was made in five cases. They were one case of nonvisualized intrahepatic stones, one case of hepatoma PTC diagnosed as cholangiocarcinoma, one case of pancreatic cancer diagnosed as cholangiocarcinoma, one case of clonorchiasis diagnosed as biliary stones and one case of normal CBD which was diagnosed as distal CBD cancer. And we experienced one case of bile peritonitis as complication, who was 35 year-old female patient with multiple CBD stones, and aspirated about 500ml of bile stained ascites during operation.

  11. Periodic Deworming With Pyrantel For Roundworm And Hookworm Infections In A Farming Village Community.

    Guar S.D

    1988-01-01

    Full Text Available A farming village community of 512 completed one year of periodic deworming with a single 10 mg/kg oral dose of pyrantel every 3 months. Stool examination by Kato’s thick smear method showed that the prevalence of roundworm infection (ascariasis in the community decreased from 76% to 0%, and that of hookworm infection (ancylostomiasis from 60% to 0%. During the same period the mean hemoglobin increased by 2.3 +/- 0.1 g/dl and the mean body mass index (BMI increased by 0.90 +/- 0.04(P 0.01 for both the drug was tolerated very well as side effects occurred following only 6% of doses (130/2048, and only 1% of these required symptomatic treatment. Quarterly deworming with a single dose of pyrantel is an effective and acceptable method of controlling roundworm and hookworm infections in farming village community having a high prevalence of these worms, and it helps improve the general health of the population to significant degree.

  12. Percutaneous transhepatic cholangiography in obstructive jaundice

    Chun, Kang Uoo; Choi, Young Dae; Park, Jin Hoon; Min, Byung Chae; Yoon, Jong Sup [Han Gang Sacred Heart Hospital Hallym College, Seoul (Korea, Republic of)

    1983-03-15

    Although many invasive studies in the biliary tract disease are replaced by noninvasive techniques such as ultrasonography and computed tomography, PTC does still play an important role in diagnosis of obstructive jaundice. Authors had performed 42 patients of PTC with Chiba needle at the department of radiology, Han Gang Sacred Heart Hospital for 4 years from January 1978 to April 1982. And we reviewed literatures. The results were as follows: 1. Forty two patients of PTC were 22 males and 20 females. The success rate was 90.5% (38/42). The failed 4 cases of PTC were nonobstructive hepatobiliary diseases. 2. The PTC diagnosis of 38 cases were biliary stone (21 cases), cholangiocarcinoma (7 cases), pancreatic carcinoma (2 cases), hepatoma (2 cases), ascariasis (2 cases), and clonorchiasis (1 case), and the remainders were normal. 3. We made 2 cases of misdiagnosis on the basis of PTC findings. They were one case of distal CBD stone with severe cholangitis diagnosed as ampullary carcinoma and another case of proximal CBD stone with cholangitis diagnosed as pancreas carcinoma. 4. We experienced 2 cases of complication such as sepsis and severe hypotension, but they were recovered.

  13. Ascaris lumbricoides in neonate: evidence of congenital transmission of intestinal nematodes Ascaris lumbricoides em neonato: evidências da transmissão congênita de nematóides intestinais

    Leda Maria da Costa-Macedo

    1990-10-01

    Full Text Available Clinical and epidemiological study of a forty-days-old infant with a diarrheic condition and insufficient development led to the coprological diagnosis of ascariasis and possible congenital infection. Specific treatment with levamizole, resulted in clinical and parasitological cure, in addition to gain of weight up to normal levels. Maternal parasitism had been diagnosed two months before labor and proved beyond doubt during the ensuing epidemiological inquiry.O estudo clínico e epidemiológico do caso de uma criança, com quarenta dias de idade, que apresentava quadro diarréico e desenvolvimento insuficiente desde o nascimento, conduziu ao diagnóstico coprológico de ascaríase e à hipótese de tratar-se de uma infecção congênita. O tratamento específico, com levamizol, produziu cura clínica e parasitológica, e um ganho de peso pelo qual a criança logo alcançou os níveis normais para a idade. O parasitismo materno havia sido diagnosticado dois meses antes do parto e foi confirmado, plenamente, por ocasião do inquérito epidemiológico que realizamos. As razões para se admitir a hipótese de transmissão congênita são apresentadas no trabalho.

  14. "EVALUATION OF THE EFFECT OF OXANTEL – PYRANTEL ON VARIOUS SOIL TRANSMITTED HELMINTHS IN IRAN "

    E. Farahmandian

    1977-08-01

    Full Text Available The effect of a combination of Oxantel- Pyrantel with a single dose of 10 mg/ kg body weight on Trichuris trichiura, Ascaris, Trichostrongylus spp. and Ancylostoma duodenale has been evaluated among the population of two rural areas in Khuzestan, Southwest Iran (41 persons and Isfahan, Central (30 persons. All patients were infected with Trichuris trichiura and some simultaneously with one or more other helminthes. In addition to stool examinations, to elucidate the possible side- effects, several blood and urine tests were conducted before and after treatment. A cure rate of 83% has been found among Trichuris cases treated in both areas. Cure rates observes for ascariasis and trichostrongyliasis were 93. 3% and 23% in Khuzestan, as well as 90% and 50% in Isfahan, respectively. Cure rate for ancylostomiasis was 86% in Khuzestan.Significant reduction in the mean number of egg.gr of faeces has been observed.Side- effects encountered were mild and transient. The promisisng effect of this drug on soil – transmitted helminthes, particulary Trichuris trichiura has been proven.

  15. Percutaneous transhepatic cholangiographic evaluation of obstructive jaundice

    PTC is the single most valuable diagnostic method available to evaluate the size, shape and site of the causes of obstructive jaundice among various radiological procedures. The authors reviewed and radiologically classified the PTC films of 203 cases of obstructive jaundice from July, 1977 to June, 1983 at Presbyterian Medical Center, Jeonju confirmed clinically, operatively and pathologically. The results are as follows; 1. The most common cause of obstructive jaundice was bile duct stone (64/203: 31.53%) and the other causes were bile duct cancer (43/203: 21.18%), pancreas cancer (41/203: 20.19%), biliary ascariasis and/or clonorchiasis (20/203: 9.8%), ampulla and duodenal cancer (7/203: 3.45%), fibrotic stenosis of sphincter of Oddi (6/203: 2.96%) etc. in the order. Of these primary involvement with cancer was more frequent (91/203: 44.33%) than stone. 3. The average maximal diameter of extrahepatic bile duct just proximal to the site of obstruction or stenosis by stones or by cancers was nearly equal (2.36 cm : 2.38 cm). 4. Cancers caused complete bile duct obstruction in about 75% (68/91) of cases and also were associated with intrahepatic duct dilatation about 92% (84/91) of cases. But in contrast biliary calculi showed good drainage of contrast medium in 75% (48/64) of cases and 92% (59/64) showed normal diameter

  16. Evaluation of a di-O-methylated glycan as a potential antigenic target for the serodiagnosis of human toxocariasis.

    Elefant, G R; Roldán, W H; Seeböck, A; Kosma, P

    2016-04-01

    Serodiagnosis of human toxocariasis is based on the detection of specific IgG antibodies by the enzyme-linked immunosorbent assay (ELISA) using Toxocara larvae excretory-secretory (TES) antigens, but its production is a laborious and time-consuming process being also limited by the availability of adult females of T. canis as source for ova to obtain larvae. Chemical synthesis of the di-O-methylated (DiM) glycan structure found in the TES antigens has provided material for studying the antibody reactivity in a range of mammalian hosts, showing reactivity with human IgM and IgG. In this study, we have evaluated the performance of the DiM glycan against a panel of sera including patients with toxocariasis (n = 60), patients with other helminth infections (n = 75) and healthy individuals (n = 94), showing that DiM is able to detect IgG antibodies with a sensitivity and specificity of 91·7% and 94·7%, respectively, with a very good agreement with the TES antigens (kappa = 0·825). However, cross-reactivity was observed in some sera from patients with ascariasis, hymenolepiasis and fascioliasis. These results show that the DiM glycan could be a promising antigenic tool for the serodiagnosis of human toxocariasis. PMID:26896376

  17. Pathogenesis and Management of Hepatolithiasis: A Report of Two Cases.

    Dey, Biswajit; Kaushal, Gourav; Jacob, Sajini Elizabeth; Barwad, Adarsh; Pottakkat, Biju

    2016-03-01

    Hepatolithiasis or primary intrahepatic stones are prevalent in the Far-East countries such as Korea, Japan and Taiwan. It has been associated with helminthiasis, bacterial infections, environmental and dietary factors. Despite high prevalence of helminthiasis like ascariasis, poor environmental condition and low protein diet, India and Middle-East countries have a low incidence of hepatolithiasis. We report two cases of hepatolithiasis associated with bacterial infections and were surgically managed. The first case is a 45-year-old female presenting with upper abdominal pain and fever. She had multiple calculi in intrahepatic biliary radicles, common bile duct, common hepatic duct and gall bladder. She was managed by cholecystectomy, left lateral liver sectionectomy, choledochoscopy assisted stone clearance of the residual liver and Roux-en-Y hepatico-jejunostomy. The second case is a 60-year-old female presenting with epigastric pain and fever and past history of cholecystectomy for cholelithiasis. She had multiple right and left intrahepatic calculi and managed by left lateral liver sectionectomy with excision of CBD and Roux-en-Y hepatico-jejunostomy. Both the cases showed growth of bacteria in the culture of the intraoperatively collected bile. PMID:27134934

  18. Percutaneous transhepatic cholangiography using fine needle

    In recent years, percutaneous transhepatic cholangiography (PTC) using fine needle has become widely employed as the procedure of choice for direct opacification of the biliary trees because of its high success rate, easy performance and relative low complication rate. Authors present the clinical and PTC findings of experienced cases during last four years, from May 1976 to June 1980, at the Department of Radiology, Korea University Hospital. We tried to study of PTC in 44 cases, 32 males and 12 females, and succeeded in visualization of bile ducts in 41 cases, but the other three cases were failed to visualize the bile ducts. Final confirmative diagnosis was achieved in 29 cases by operation, laparoscopy and other clinical methods. The PTC diagnosis was correct in 24 of 29 cases, and the others were incorrect. The 29 final diagnosis was including 13 cases of biliary stones, 6 cases of biliary cancer, 3 cases of pancreatic cancer, 3 cases of clonorchiasis, one case of CBD ascariasis and 3 cases of others. Incorrect PTC diagnosis was made in five cases. They were one case of nonvisualized intrahepatic stones, one case of hepatoma PTC diagnosed as cholangiocarcinoma, one case of pancreatic cancer diagnosed as cholangiocarcinoma, one case of clonorchiasis diagnosed as biliary stones and one case of normal CBD which was diagnosed as distal CBD cancer. And we experienced one case of bile peritonitis as complication, who was 35 year-old female patient with multiple CBD stones, and aspirated about 500ml of bile stained ascites during operation

  19. Multiple Exposures to Ascaris suum Induce Tissue Injury and Mixed Th2/Th17 Immune Response in Mice.

    Nogueira, Denise Silva; Gazzinelli-Guimarães, Pedro Henrique; Barbosa, Fernando Sérgio; Resende, Nathália Maria; Silva, Caroline Cavalcanti; de Oliveira, Luciana Maria; Amorim, Chiara Cássia Oliveira; Oliveira, Fabrício Marcus Silva; Mattos, Matheus Silvério; Kraemer, Lucas Rocha; Caliari, Marcelo Vidigal; Gaze, Soraya; Bueno, Lilian Lacerda; Russo, Remo Castro; Fujiwara, Ricardo Toshio

    2016-01-01

    Ascaris spp. infection affects 800 million people worldwide, and half of the world population is currently at risk of infection. Recurrent reinfection in humans is mostly due to the simplicity of the parasite life cycle, but the impact of multiple exposures to the biology of the infection and the consequences to the host's homeostasis are poorly understood. In this context, single and multiple exposures in mice were performed in order to characterize the parasitological, histopathological, tissue functional and immunological aspects of experimental larval ascariasis. The most important findings revealed that reinfected mice presented a significant reduction of parasite burden in the lung and an increase in the cellularity in the bronchoalveolar lavage (BAL) associated with a robust granulocytic pulmonary inflammation, leading to a severe impairment of respiratory function. Moreover, the multiple exposures to Ascaris elicited an increased number of circulating inflammatory cells as well as production of higher levels of systemic cytokines, mainly IL-4, IL-5, IL-6, IL-10, IL-17A and TNF-α when compared to single-infected animals. Taken together, our results suggest the intense pulmonary inflammation associated with a polarized systemic Th2/Th17 immune response are crucial to control larval migration after multiple exposures to Ascaris. PMID:26814713

  20. Biliary Fasciola gigantica infestation in a nonendemic area--An intraoperative surprise.

    Menon, Prema; Sinha, Amit Kumar; Rao, Katragadda Lakshmi Narasimha; Khurana, Sumeeta; Lal, Sadhana; Thapa, Babu Ram

    2015-11-01

    A 7year old girl infected with the zoonotic trematode, Fasciola gigantica is reported because of the extreme rarity of this condition in our region. Because of the overlap in symptomatology and radiological features, the more common amebic/pyogenic liver abscess in the initial hepatic migratory phase and later choledochal cyst/biliary ascariasis when the parasite was finally located in the extrahepatic bile ducts, were thought of delaying effective treatment. The diagnosis was confirmed only by surgical exploration. The characteristic contrast enhanced computed tomography scan features retrospectively identified were multiple clustered hypodense lesions in the liver with peripheral enhancement in the acute hepatic migratory phase, and periportal tracking in the previously affected areas of the liver with biliary dilatation and a linear hypointense lesion within the common bile duct in the chronic phase. Although a known association, she did not have eosinophilia. This child, who became symptomatic at the age of 5.5years, also appears to be one of the youngest patients reported with Fasciola gigantica. PMID:26362003

  1. African Program for Onchocerciasis Control 1995-2010: Impact of Annual Ivermectin Mass Treatment on Off-Target Infectious Diseases.

    Krotneva, Stanimira P; Coffeng, Luc E; Noma, Mounkaila; Zouré, Honorat G M; Bakoné, Lalle; Amazigo, Uche V; de Vlas, Sake J; Stolk, Wilma A

    2015-01-01

    Since its initiation in 1995, the African Program for Onchocerciasis Control (APOC) has had a substantial impact on the prevalence and burden of onchocerciasis through annual ivermectin mass treatment. Ivermectin is a broad-spectrum anti-parasitic agent that also has an impact on other co-endemic parasitic infections. In this study, we roughly assessed the additional impact of APOC activities on the burden of the most important off-target infections: soil-transmitted helminthiases (STH; ascariasis, trichuriasis, hookworm, and strongyloidiasis), lymphatic filariasis (LF), and scabies. Based on a literature review, we formulated assumptions about the impact of ivermectin treatment on the disease burden of these off-target infections. Using data on the number of ivermectin treatments in APOC regions and the latest estimates of the burden of disease, we then calculated the impact of APOC activities on off-target infections in terms of disability-adjusted life years (DALYs) averted. We conservatively estimated that between 1995 and 2010, annual ivermectin mass treatment has cumulatively averted about 500 thousand DALYs from co-endemic STH infections, LF, and scabies. This impact comprised approximately an additional 5.5% relative to the total burden averted from onchocerciasis (8.9 million DALYs) and indicates that the overall cost-effectiveness of APOC is even higher than previously reported. PMID:26401658

  2. Geohelminth Infections and Nutritional Status of Preschool Aged Children in a Periurban Settlement of Ogun State.

    Omitola, O O; Mogaji, H O; Oluwole, A S; Adeniran, A A; Alabi, O M; Ekpo, U F

    2016-01-01

    This study assessed the geohelminth and nutritional status of preschoolers in a periurban community of Ogun state. Fresh stool specimens were collected for laboratory analysis, processed using ether concentration method, and examined under the microscope for geohelminth ova. Demographic characteristics and daily nutrient intake of children were subjectively assessed during an interview session with parents, following anthropometric data collection. Data obtained were analysed using a statistical software for Windows. Nutritional indicators such as underweight, stunting, and wasting were computed from anthropometric data. Results showed an overall prevalence of 39.2% and 12.4% for Ascariasis and Hookworm infection, respectively, with no significant difference (P > 0.05) between the sexes. Prevalence of nutritional indicators was 52.6%, 35.1%, 34.0%, and 9.3% for underweight, stunting, wasting, and thinness conditions, respectively. A good proportion of the malnourished preschoolers were free of Ascaris infection but infected with Hookworm parasite. The adverse effect of geohelminth infection cannot still be ignored in impaired growth, reduced survival, poor development, and cognitive performance of preschoolers. Therefore promotion of adequate health education program on measures of preventing geohelminth infections is needed. PMID:27034905

  3. Percutaneous transhepatic cholangiography in obstructive jaundice

    Although many invasive studies in the biliary tract disease are replaced by noninvasive techniques such as ultrasonography and computed tomography, PTC does still play an important role in diagnosis of obstructive jaundice. Authors had performed 42 patients of PTC with Chiba needle at the department of radiology, Han Gang Sacred Heart Hospital for 4 years from January 1978 to April 1982. And we reviewed literatures. The results were as follows: 1. Forty two patients of PTC were 22 males and 20 females. The success rate was 90.5% (38/42). The failed 4 cases of PTC were nonobstructive hepatobiliary diseases. 2. The PTC diagnosis of 38 cases were biliary stone (21 cases), cholangiocarcinoma (7 cases), pancreatic carcinoma (2 cases), hepatoma (2 cases), ascariasis (2 cases), and clonorchiasis (1 case), and the remainders were normal. 3. We made 2 cases of misdiagnosis on the basis of PTC findings. They were one case of distal CBD stone with severe cholangitis diagnosed as ampullary carcinoma and another case of proximal CBD stone with cholangitis diagnosed as pancreas carcinoma. 4. We experienced 2 cases of complication such as sepsis and severe hypotension, but they were recovered

  4. ERCP in acute pancreatitis

    Jijo V Cherian; Joye Varghese Selvaraj; Rajesh Natrayan; Jayanthi Venkataraman

    2007-01-01

    BACKGROUND:The role of endoscopic retrograde cholangiopancreatography (ERCP) in the management of acute pancreatitis has evolved over years since its introduction in 1968. Its importance in diagnosing the etiology of pancreatitis has steadily declined with the advent of less invasive diagnostic tools. The therapeutic implications of ERCP in acute pancreatitis are many fold and are directed towards management of known etiological factors or its related complications. This article highlights the current status of ERCP in acute pancreatitis. DATA SOURCES:An English literature search using PubMed database was conducted on ERCP in acute pancreatitis, the etiologies and complications of pancreatitis amenable to endotherapy and other related subjects, which were reviewed. RESULTS: ERCP serves as a primary therapeutic modality for management of biliary pancreatitis in speciifc situations, pancreatitis due to microlithiasis, speciifc types of sphincter of Oddi dysfunction, pancreas divisum, ascariasis and malignancy. In recurrent acute pancreatitis and smoldering pancreatitis it has a deifnite therapeutic utility. Complications of acute pancreatitis including pancreatic-duct disruptions or leaks, benign pancreatic-lfuid collections and pancreatic necrosis can be beneifcially dealt with. Intraductal ultrasound and pancreatoscopy during ERCP are useful in detecting pancreatic malignancy. CONCLUSIONS:The role of ERCP in acute pancreatitis is predominantly therapeutic and occasionally diagnostic. Its role in the management continues to evolve and advanced invasive procedures should be undertaken only in centers dedicated to pancreatic care.

  5. Parasitic infections in wild ruminants and wild boar

    Ilić Tamara

    2011-01-01

    Full Text Available Wild ruminants and wild boar belong to the order Artiodactyla, the suborders Ruminantia and Nonruminantia and are classified as wild animals for big game hunting, whose breeding presents a very important branch of the hunting economy. Diseases caused by protozoa are rarely found in wild ruminants in nature. Causes of coccidiosis, cryptosporidiosis, toxoplasmosis, sarcocystiosis, giardiasis, babesiosis, and theileriosis have been diagnosed in deer. The most significant helminthoses in wild ruminants are fasciosis, dicrocoeliasis, paramphistomosis, fascioloidosis, cysticercosis, anoplocephalidosis, coenurosis, echinococcosis, pulmonary strongyloidiasis, parasitic gastroenteritis, strongyloidiasis and trichuriasis, with certain differences in the extent of prevalence of infection with certain species. The most frequent ectoparasitoses in wild deer and doe are diseases caused by ticks, mites, scabies mites, and hypoderma. The most represented endoparasitoses in wild boar throughout the world are coccidiosis, balantidiasis, metastrongyloidiasis, verminous gastritis, ascariasis, macracanthorhynchosis, trichinelosis, trichuriasis, cystecercosis, echinococcosis, and less frequently, there are also fasciolosis and dicrocoeliasis. The predominant ectoparasitoses in wild boar are ticks and scabies mites. Knowledge of the etiology and epizootiology of parasitic infections in wild ruminants and wild boar is of extreme importance for the process of promoting the health protection system for animals and humans, in particular when taking into account the biological and ecological hazard posed by zoonotic infections.

  6. Neglected infections of poverty in the United States of America.

    Hotez, Peter J

    2008-01-01

    In the United States, there is a largely hidden burden of diseases caused by a group of chronic and debilitating parasitic, bacterial, and congenital infections known as the neglected infections of poverty. Like their neglected tropical disease counterparts in developing countries, the neglected infections of poverty in the US disproportionately affect impoverished and under-represented minority populations. The major neglected infections include the helminth infections, toxocariasis, strongyloidiasis, ascariasis, and cysticercosis; the intestinal protozoan infection trichomoniasis; some zoonotic bacterial infections, including leptospirosis; the vector-borne infections Chagas disease, leishmaniasis, trench fever, and dengue fever; and the congenital infections cytomegalovirus (CMV), toxoplasmosis, and syphilis. These diseases occur predominantly in people of color living in the Mississippi Delta and elsewhere in the American South, in disadvantaged urban areas, and in the US-Mexico borderlands, as well as in certain immigrant populations and disadvantaged white populations living in Appalachia. Preliminary disease burden estimates of the neglected infections of poverty indicate that tens of thousands, or in some cases, hundreds of thousands of poor Americans harbor these chronic infections, which represent some of the greatest health disparities in the United States. Specific policy recommendations include active surveillance (including newborn screening) to ascertain accurate population-based estimates of disease burden; epidemiological studies to determine the extent of autochthonous transmission of Chagas disease and other infections; mass or targeted treatments; vector control; and research and development for new control tools including improved diagnostics and accelerated development of a vaccine to prevent congenital CMV infection and congenital toxoplasmosis. PMID:18575621

  7. Prevalence and risk factors for giardiasis and soil-transmitted helminthiasis in three municipalities of Southeastern Minas Gerais State, Brazil: risk factors for giardiasis and soil-transmitted helminthiasis.

    Pinheiro, Izabella de Oliveira; de Castro, Milton Ferreira; Mitterofhe, Adalberto; Pires, Flávia Alves Condé; Abramo, Clarice; Ribeiro, Luiz Cláudio; Tibiriçá, Sandra Helena Cerrato; Coimbra, Elaine Soares

    2011-05-01

    Giardiasis and soil-transmitted helminthiasis (STH) are parasitic diseases that are among the major health concerns observed in economically disadvantaged populations of developing countries, and have clear social and environmental bases. In Brazil, there is a lack of epidemiologic data concerning these infections in the study area, whose inhabitants have plenty of access to health care services, including good dwelling and adequate sanitary conditions. In this survey we investigated the risk factors for giardiasis and STH in three municipalities with good sanitation, situated in Minas Gerais state, Brazil. A cross-sectional survey was conducted in the municipalities of Piau, Coronel Pacheco and Goianá, in both urban and rural areas. The fieldwork consisted of a questionnaire and the examination of 2,367 stool samples using the Hoffmann, Pons and Janer method. Of all individuals from the population sample, 6.1% were found infected with the parasitic diseases included in this work. Hookworm infection was the most prevalent disease, followed by giardiasis, trichuriasis and ascariasis. Infection was more prevalent in males (8.1%, p access to public health care and education. PMID:21243507

  8. Ultrasonographic appearance of Ascaris lumbricoides in the small bowel.

    Mahmood, T; Mansoor, N; Quraishy, S; Ilyas, M; Hussain, S

    2001-03-01

    Roundworm infestation, one of the most common helminthic diseases worldwide, is caused by Ascaris lumbricoides, one of the largest parasites that infests the human bowel. A lumbricoides is virtually universal at some stage of childhood in semitropical and tropical regions. This study describes our experience with the ultrasonographic appearance of intestinal ascariasis in 84 patients, 2.5 to 42 years of age, examined over 2 years beginning October 1997. The patients' conditions ranged from acute intestinal obstruction to no clinical features pertaining to obstruction. Ultrasonographic examination was performed with an Echocee power Doppler real-time unit with a variable-frequency 3.7-MHz convex, 7.5-MHz linear probe. In longitudinal section the Ascaris worm presented as a linear intraluminal mass with 3 or 4 linear echogenic interfaces; in the cross section, it was round, sometimes appearing as a "target" sign. Some worms also showed serpentine movements. Sonographic examination of the patients in the left lateral decubitus position after ingestion of water improved detection and visualization of the worms in some cases. It is concluded that A lumbricoides in the small bowel has a sonographic appearance that can be recognized by the wary observer. PMID:11270532

  9. KERUGIAN FINANSIAL AKIBAT KECACINGAN: STUDI DI KABUPATEN NUNUKAN

    Liestiana Indriyati

    2015-04-01

    Full Text Available ABSTRACTHelminthiasis is one cause of nutritional anemia that impairs cognitive function, productivity and physical growth and development of children. This paper discuss the nutritional and financial losses caused by the helminthiasis. This study was observational research using cross-sectional design. The population were all primary school children in Nunukan, the number of sample were 1126 school age children enrolled in nine primary health centers working area (Nunukan, Sedadap, Setabu, Sungai Nyamuk, Aji Kuning, Sembakung, Pembeliangan, Mansalong and Sanur during March to December 2010. Ascaris lumbricoides consume carbohydrates as much as 0.14 g/worm/day and 0.035 g protein/day. While Trichuris trichiura fed on blood as much as 0,005 cc/ worm/day and Hookworm as much as 0.2 cc/worm/day. The price of carbohydrates assumed to be the rice price Rp.7.199,49/kg, the price of protein assumed to be beef price Rp.30.000/kg and blood Rp.250.000/pack 250cc (Rp.1000/cc. The results showed that prevalence of ascariasis was 10.3 percent, trichuriasis 8.97 percent and hookworm 2.93 percent . Based on the calculation of nutrients and financial losses, during 2010 Nunukan suffered loss of carbohydrate of 2068.9 kg/year worth Rp. 14.895.075,- , protein loss of 517.23 kg/year worth Rp.32.530.588,- , and blood loss amounted to 1,220,241.17 cc/year worth Rp.1.220.241.100,- the total financial losses due to helminthiasis amounted to Rp.1.276.666.763,-.Keywords : helminthiasis,nutrition, financial disadvantageABSTRAKKecacingan disebabkan oleh infestasi cacing parasit merupakan salah satu penyebab anemia gizi, dapat mempengaruhi tingkat kecerdasan, produktivitas, pertumbuhan serta perkembangan fisik dan mental anak-anak. Kecacingan juga menyebabkan gangguan kemampuan belajar, dan dalam jangka panjang akan berakibat menurunnya kualitas Sumber Daya Manusia (SDM. Tulisan ini membahas tentang perhitungan kerugian nutrisi dan finansial yang diakibatkan oleh penyakit

  10. ANALISIS MODEL FAKTOR RISIKO YANG MEMPENGARUHI INFEKSI KECACINGAN YANG DITULARKAN MELALUI TANAH PADA SISWA SEKOLAH DASAR DI DISTRIK ARSO KABUPATEN KEEROM, PAPUA

    Semuel Sandy

    2015-05-01

    Full Text Available AbstrakInfeksi kecacingan yang ditularkan melalui tanah masih merupakan masalah kesehatan di daerah pedesaan. Parasit cacing yang paling banyak menginfeksi adalah Ascaris lumbricoides, Cacing tambang (hookworm dan Trichuris trichiura. Penyakit ini umumnya terkait dengan faktor sosial-ekonomi, perilaku hidup bersih dan sehat. Penelitian bertujuan mengetahui prevalensi infeksi kecacingan yang ditularkan melalui tanah pada siswa sekolah dasar (SD di Distrik Arso Kabupaten Keerom dan mengetahui hubungan infeksi kecacingan yang ditularkan melalui tanah terhadap status gizi, status anemia, sosial ekonomi orang tua murid, sanitasi lingkungan dan higiene perorangan. Penelitian menggunakan metode potong lintang (cross sectional dengan melakukan pengukuran antropometri tinggi badan, berat badan, pengukuran kadar Hb untuk melihat status anemia pada 224 murid SD di Distrik Arso Kabupaten Keerom. Pengumpulan data sosial-ekonomi, sanitasi, higiene perorangan mengunakan kuesioner. Pemeriksaan infeksi kecacingan menggunakan metode Kato-Katz dan pengukuran variable intensitas infeksi berdasarkan metode WHO. Analisis statistik bivariat dan multivariat digunakan untuk melihat variabel faktor risiko yang berperan dalam penularan infeksi kecacingan yang ditularkan melalui tanah. Hasil penelitian menunjukkan infeksi kecacingan pada anak sekolah dasar didapatkan sebesar 29,9% dari 224 murid SD. Jumlah murid sekolah dasar yang terinfeksi ascariasis 23,2%, terinfeksi cacing tambang 7,6% dan terinfeksi trikhuriasis 4,9%. Sedangkan murid SD yang mengalami anemia 12,5% dan indeks massa tubuh (IMT kurang 79,5%. Hasil analisis multivariat menggunakan regresi logistik diperoleh variabel faktor risiko yang berkaitan dengan infeksi kecacingan STH yaitu: kebiasaan mencuci tangan sebelum makan dengan air dan sabun (OR = 0,33; 95% CI 0, 14-0, 78 dan nilai p = 0,012. Dari hasil penelitian disimpulkan bahwa faktor risiko yang berhubungan dengan kejadian infeksi kecacingan yang

  11. Modelagem geoestatística da infecção por Ascaris lumbricoides Geostatistical modeling of Ascaris lumbricoides infection

    Bruno de Paula Menezes Drumond Fortes

    2004-06-01

    Full Text Available O estudo tem por objetivo modelar a distribuição espacial da ocorrência de ascaríase, utilizando mapas de risco mediante técnicas de geoprocessamento e análise geoestatística. Com base no banco de dados do PAISQUA, foram selecionados 19 setores censitários do Rio de Janeiro. Foram amostradas e georreferenciadas, no centróide de seu respectivo domicílio, 1.550 crianças com idade de 1 a 9 anos. Mapas de risco de Ascaris lumbricoides foram gerados usando krigagem indicadora. Com base na validação cruzada, os valores estimados foram comparados aos observados por intermédio da curva ROC. Um modelo de semivariograma isotrópico esférico com alcance de 30m e efeito pepita de 50% foi empregado na krigagem ordinária indicadora para a construção de um mapa de probabilidade de infecção por A. lumbricoides. A acurácia global, mensurada por meio da área sob a curva ROC, mostrou-se significativa. O uso da krigagem ordinária indicadora permitiu a modelagem de mapas de risco valendo-se da amostra de uma variável indicadora. O emprego das técnicas de análise estatística espacial mostrou-se adequado na predição da ocorrência do fenômeno, não ficando restrita a delimitações político-administrativas da região.The following study intends to model the spatial distribution of ascariasis, through the use of geoprocessing and geostatistic analysis. The database used in the study was taken from the PAISQUA project, including a coproparasitologic and domiciliary survey, conducted in 19 selected census tracts of Rio de Janeiro State, Brazil, randomly selecting a group of 1,550 children aged 1 to 9 years old plotting them in their respective domicile's centroids. Risk maps of Ascaris lumbricoides were generated by indicator kriging. The estimated and observed values from the cross-validation were compared using a ROC curve. An isotropic spherical semivariogram model with a range of 30m and nugget effect of 50% was employed in ordinary

  12. Fascioliasis and intestinal parasitoses affecting schoolchildren in Atlixco, Puebla State, Mexico: epidemiology and treatment with nitazoxanide.

    José Lino Zumaquero-Ríos

    2013-11-01

    Full Text Available BACKGROUND: The Atlixco municipality, Puebla State, at a mean altitude of 1840 m, was selected for a study of Fasciola hepatica infection in schoolchildren in Mexico. This area presents permanent water collections continuously receiving thaw water from Popocatepetl volcano (5426 m altitude through the community supply channels, conforming an epidemiological scenario similar to those known in hyperendemic areas of Andean countries. METHODOLOGY AND FINDINGS: A total of 865 6-14 year-old schoolchildren were analyzed with FasciDIG coproantigen test and Lumbreras rapid sedimentation technique, and quantitatively assessed with Kato-Katz. Fascioliasis prevalences ranged 2.94-13.33% according to localities (mean 5.78%. Intensities were however low (24-384 epg. The association between fascioliasis and the habit of eating raw vegetables was identified, including watercress and radish with pronouncedly higher relative risk than lettuce, corncob, spinach, alfalfa juice, and broccoli. Many F. hepatica-infected children were coinfected by other parasites. Entamoeba histolytica/dispar, Giardia intestinalis, Blastocystis hominis, Hymenolepis nana and Ascaris lumbricoides infection resulted in risk factors for F. hepatica infection. Nitazoxanide efficacy against fascioliasis was 94.0% and 100% after first and second treatment courses, respectively. The few children, for whom a second treatment course was needed, were concomitantly infected by moderate ascariasis burdens. Its efficacy was also very high in the treatment of E. histolytica/E. dispar, G. intestinalis, B. hominis, H. nana, A. lumbricoides, Trichuris trichiura, and Enterobius vermicularis. A second treatment course was needed for all children affected by ancylostomatids. CONCLUSIONS: Fascioliasis prevalences indicate this area to be mesoendemic, with isolated hyperendemic foci. This is the first time that a human fascioliasis endemic area is described in North America. Nitazoxanide appears as an

  13. Non Obstetric Causes and Presentation of Acute Abdomen among the Pregnant Women.

    Monoarul Haque

    2014-09-01

    Full Text Available To identify the non-obstetric causes and presentation of acute abdomen among pregnant women.This was a cross sectional hospital-based study among 128 pregnant women by face to face interview using a semi-structured questionnaire. This study was conducted at the Gynecology & Obstetric Ward of 250 Bed General Hospital, Noakhali, Bangladesh, from January to August 2013. Data were analyzed by a software package used for statistical analysis (SPSS version 11.5 (SPSS, Inc., Chicago, IL, USA.Mean age of participants was 25±4 years. Our findings showed that 81% were Muslim, 67% were lower middle income group, as well as 47% completed primary level of education. The results revealed that 28% had biliary ascariasis, 24% had peptic ulcer disease and 10% had lower urinary tract infection. We also found that 6% had acute pyelonephritis, 6% had acute gastroenteritis, 6% had acute cholecystitis, 6% had acute appendicitis, 2% had acute pancreatitis, 3% had choledocolithiasis, 2% had ovarian solid mass, 2% had twisted ovarian cyst, 4% had renal colic, and 1% had renal calculus. In non-obstetrical presentation of acute abdomen, the study found that 84% of respondents complained their pain lasting more than 24 hours. Besides, half of respondents felt pain in epigastrium and right hypochondrium. Cramping, prickling and aching type of pain were more, while 66% suffered from continuous pain. Our results also showed that 73% did not explain any aggravating factor and relieving factor, and the rest said food, fasting state and position change aggravated pain as well as relieved pain.The study concludes that precise diagnosis of the acute abdomen in pregnant women by continual updating of abdominal assessment knowledge, and clinical skills is necessary in the management of abdominal pain in obstetric settings.

  14. Human anthelminthic vaccines: Rationale and challenges.

    Hotez, Peter J; Strych, Ulrich; Lustigman, Sara; Bottazzi, Maria Elena

    2016-06-24

    Helminth infections are the most common afflictions of humankind, affecting almost every single person living in profound poverty. Through mass drug administration (MDA) we have seen sharp declines in the global prevalence of some helminth infections, including lymphatic filariasis, onchocerciasis, and ascariasis. However, since 1990, there has been no appreciable decrease in the global prevalence of hookworm infection, schistosomiasis, or food-borne trematodiases. Through the activities of a non-profit product development partnerships and two research institutes, a total of five human anthelmintic vaccines for hookworm infection (two) and schistosomiasis (three) have advanced from discovery through manufacture and are now in Phase 1 clinical testing. At least three additional antigens, including two for onchocerciasis and one for schistosomiasis, are also advancing through preclinical development with the intention of moving into the clinic soon. These preventive human anthelmintic vaccines could be used as stand-alone technologies administered to infants as part of the Expanded Program on Immunization (EPI), or together with anthelmintic drugs in programs linked to MDA. Significant hurdles though could hinder the advancement of these vaccines into later-stage clinical and product development and licensure. They include the absence of a major pharma partner (and the resultant access to adjuvants and industrial scale manufacturing expertise), an uncharted roadmap for how to introduce anthelmintic vaccines into appropriate health systems, uncertain global access and regulatory strategies that might need to rely on developing country vaccine manufacturers and national regulatory authorities, and the lack of innovative financing schemes. However, the public health and economic benefits of introducing these vaccines could be massive and therefore deserve international attention and support. PMID:27171753

  15. Neglected infections of poverty in the United States of America.

    Peter J Hotez

    Full Text Available In the United States, there is a largely hidden burden of diseases caused by a group of chronic and debilitating parasitic, bacterial, and congenital infections known as the neglected infections of poverty. Like their neglected tropical disease counterparts in developing countries, the neglected infections of poverty in the US disproportionately affect impoverished and under-represented minority populations. The major neglected infections include the helminth infections, toxocariasis, strongyloidiasis, ascariasis, and cysticercosis; the intestinal protozoan infection trichomoniasis; some zoonotic bacterial infections, including leptospirosis; the vector-borne infections Chagas disease, leishmaniasis, trench fever, and dengue fever; and the congenital infections cytomegalovirus (CMV, toxoplasmosis, and syphilis. These diseases occur predominantly in people of color living in the Mississippi Delta and elsewhere in the American South, in disadvantaged urban areas, and in the US-Mexico borderlands, as well as in certain immigrant populations and disadvantaged white populations living in Appalachia. Preliminary disease burden estimates of the neglected infections of poverty indicate that tens of thousands, or in some cases, hundreds of thousands of poor Americans harbor these chronic infections, which represent some of the greatest health disparities in the United States. Specific policy recommendations include active surveillance (including newborn screening to ascertain accurate population-based estimates of disease burden; epidemiological studies to determine the extent of autochthonous transmission of Chagas disease and other infections; mass or targeted treatments; vector control; and research and development for new control tools including improved diagnostics and accelerated development of a vaccine to prevent congenital CMV infection and congenital toxoplasmosis.

  16. Fascioliasis and Intestinal Parasitoses Affecting Schoolchildren in Atlixco, Puebla State, Mexico: Epidemiology and Treatment with Nitazoxanide

    Zumaquero-Ríos, José Lino; Sarracent-Pérez, Jorge; Rojas-García, Raúl; Rojas-Rivero, Lázara; Martínez-Tovilla, Yaneth; Valero, María Adela; Mas-Coma, Santiago

    2013-01-01

    Background The Atlixco municipality, Puebla State, at a mean altitude of 1840 m, was selected for a study of Fasciola hepatica infection in schoolchildren in Mexico. This area presents permanent water collections continuously receiving thaw water from Popocatepetl volcano (5426 m altitude) through the community supply channels, conforming an epidemiological scenario similar to those known in hyperendemic areas of Andean countries. Methodology and Findings A total of 865 6–14 year-old schoolchildren were analyzed with FasciDIG coproantigen test and Lumbreras rapid sedimentation technique, and quantitatively assessed with Kato-Katz. Fascioliasis prevalences ranged 2.94–13.33% according to localities (mean 5.78%). Intensities were however low (24–384 epg). The association between fascioliasis and the habit of eating raw vegetables was identified, including watercress and radish with pronouncedly higher relative risk than lettuce, corncob, spinach, alfalfa juice, and broccoli. Many F. hepatica-infected children were coinfected by other parasites. Entamoeba histolytica/dispar, Giardia intestinalis, Blastocystis hominis, Hymenolepis nana and Ascaris lumbricoides infection resulted in risk factors for F. hepatica infection. Nitazoxanide efficacy against fascioliasis was 94.0% and 100% after first and second treatment courses, respectively. The few children, for whom a second treatment course was needed, were concomitantly infected by moderate ascariasis burdens. Its efficacy was also very high in the treatment of E. histolytica/E. dispar, G. intestinalis, B. hominis, H. nana, A. lumbricoides, Trichuris trichiura, and Enterobius vermicularis. A second treatment course was needed for all children affected by ancylostomatids. Conclusions Fascioliasis prevalences indicate this area to be mesoendemic, with isolated hyperendemic foci. This is the first time that a human fascioliasis endemic area is described in North America. Nitazoxanide appears as an appropriate

  17. Community awareness of intestinal parasites and the prevalence of infection among community members of rural Abaye Deneba area, Ethiopia

    Liza Nyantekyi; Mengistu Legesse; Girmay Medhin; Abebe Animut; Konjit Tadesse; Chanda Macias; Abraham Degarege; Berhanu Erko

    2014-01-01

    Objective: To assess the knowledge of Abaye Deneba community members regarding intestinal parasites and prevalence of intestinal parasitic infections.Methods:Knowledge about intestinal parasites was assessed by administering a questionnaire to 345 randomly selected household heads. Parasitological stool examination of 491 randomly selected individuals was done using the formol ether concentration technique.Results:Knowledge of the Abaye Deneba community about parasitic diseases such as schistosomiasis, amoebiasis, ascariasis and taeniasis was very low. However, 204 (59.3%) members correctly responded that the cause of giardiasis is related to contaminated water and 176 (51.2%) knew how to prevent it. In some cases, respondents did correctly identify causes, symptoms of intestinal parasite infection and ways to prevent it, but they did not accurately link it to the appropriate disease caused by the different intestinal parasite species. Among the 491 stool samples examined, 50.2% of study participants showed infection with at least one intestinal parasite. Schistosoma mansoni was the most prevalent (41.3%) followed by Trichuris trichiura(9.4%), Ascaris lumbricoides (8.4%), Taenia saginata (2.4%), Enterobius vermicularis (2.0%) and hookworm (0.4%). Prevalence of schistosomiasis was highest in men aged 15-24 years.Conclusions:Intestinal parasitic infection is highly prevalent in communities of the Abaye Deneba area. Nevertheless, the knowledge of the community members about the parasite is less. Implementation of preventive chemotherapy, supplemented with health education, provision and use of sanitary facilities would be recommended to reduce morbidity and control transmission of intestinal parasites in this area.

  18. Etiological spectrum of recurrent jaundice in adults: A retrospective observational study from a tertiary care center

    Gouranga Santra

    2016-01-01

    Full Text Available Introduction: Studies regarding etiological spectrum of recurrent jaundice are rare. We conducted this study to identify the causes of recurrent jaundice in a tertiary care center. Materials and Methods: Frequency of different causes of recurrent jaundice was assessed from 130 patients attended General Medicine Department over a period of 3 years. Recurrent jaundice was considered when patients had more than one episodes of jaundice with serum bilirubin ≥3 mg/dl since childhood. Recurrent jaundice was diagnosed from past medical records, records of follow-up visits, and current clinical presentation. Causes were identified from past and present medical records of history, clinical and laboratory examinations. Results: Causes of recurrent jaundice included prehepatic (30%, hepatic (59.23%, and posthepatic (10.77 % disorders. Prehepatic disorders were Gilbert′s syndrome (GS, megaloblastic anemia, autoimmune haemolytic anemia, Wilson′s disease, G6PD deficiency, etc. Hepatic disorders were exacerbations of alcoholic hepatitis, hepatitis B and C, autoimmune hepatitis, congestive cardiac failure, sarcoidosis, benign recurrent intrahepatic cholestasis, eclampsia, pregnancy induced cholestasis, falciparum malaria, drug induced liver injury (DILI, etc. Posthepatic causes were choledocholithiasis, recurrent pancreatitis, periampullary carcinoma, choledochal cyst, ascariasis, hemobilia, HIV cholangiopathy, autoimmune pancreatitis, etc. Prehepatic jaundice cases were younger. The highest level of total bilirubin was seen in alcoholic hepatitis, DILI, and hepatitis B. Alcoholic hepatitis was the most common cause of recurrent jaundice (19.23%. GS was the most common prehepatic cause. Mean age was lowest in GS and highest in DILI. Conclusion: Etiological spectrum of recurrent jaundice includes many prehepatic, hepatic or posthepatic disorders. A larger study may enlarge the spectrum.

  19. Studies on the traditional herbal anthelmintic Chenopodium ambrosioides L.: ethnopharmacological evaluation and clinical field trials.

    Kliks, M M

    1985-01-01

    Infusions and decoctions of the leaves, roots and inflorescences of the herbaceous shrub Chenopodium ambrosioides (American wormseed, goosefoot, epazote, paico) and related species indigenous to the New World have been used for centuries as dietary condiments and as traditional anthelmintics by native peoples for the treatment of intestinal worms. Commercial preparations of oil of chenopodium and its active constituent, ascaridol, obtained by steam distillation, have been and continue to be, used with considerable success in mass treatment campaigns. Ethnopharmacological studies in a community of Mayan subsistence farmers in Chiapas, Mexico, confirmed that decoctions containing up to 300 mg of dry plant material per kg body weight (MGKGW) were widely used and traditionally highly regarded in the treatment of ascariasis. However, therapeutic doses of up to 6000 MGKGW of powdered, dried plant had no significant anthelmintic effect on the adults of Necator, Trichuris of Ascaris. Gas-liquid chromatographic analyses of plant samples used consistently demonstrated the presence of ascaridol in the expected amounts. Possible origins of subjective belief in the efficacy of C. ambrosioides as used, may be related to the positive association of spontaneous, or peristalsis-induced passage of senescent worms immediately following a therapeutic episode. It is also possible that in the past varieties of the plant containing much more ascaridol were used. The results of these controlled field studies did not sustain widely held traditional beliefs, nor the value of therapeutic practices regarding this plant. It is, therefore, essential that all indigenous ethnomedical practices be objectively evaluated for efficacy and safety using appropriate protocols before being considered for adoptation or promotion in health care programs.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:3906906

  20. Food and water security issues in Russia III: food- and waterborne diseases in the Russian Arctic, Siberia and the Far East, 2000–2011

    Alexey A. Dudarev

    2013-12-01

    Full Text Available Background . The food- and waterborne disease situation in Russia requires special attention. Poor quality of centralized water supplies and sewage systems, biological and chemical contamination of drinking water, as well as contamination of food products, promote widespread infectious diseases, significantly exceeding nationwide rates in the population living in the two-thirds of Russian northern territories. Objectives. The general aim was to assess the levels of food- and waterborne diseases in selected regions of Russian Arctic, Siberia and the Far East (for the period 2000–2011, and to compare disease levels among regions and with national levels in Russia. Study design and methods . This study is the first comparative assessment of the morbidity in these fields of the population of 18 selected regions of Russian Arctic, Siberia and the Far East, using official statistical sources. The incidences of infectious and parasitic food- and waterborne diseases among the general population (including indigenous peoples have been analyzed in selected regions (per 100,000 of population, averaged for 2000–2011. Results . Among compulsory registered infectious and parasitic diseases, there were high rates and widespread incidences in selected regions of shigellosis, yersiniosis, hepatitis A, tularaemia, giardiasis, enterobiasis, ascariasis, diphyllobothriasis, opistorchiasis, echinococcosis and trichinellosis. Conclusion . Incidences of infectious and parasitic food- and waterborne diseases in the general population of selected regions of the Russian Arctic, Siberia and the Far East (2000–2011 are alarmingly high. Parallel solutions must be on the agenda, including improvement of sanitary conditions of cities and settlements in the regions, modernization of the water supply and of the sewage system. Provision and monitoring of the quality of the drinking water, a reform of the general healthcare system and the epidemiological surveillance

  1. Patterns and risk factors of helminthiasis and anemia in a rural and a peri-urban community in Zanzibar, in the context of helminth control programs.

    Stefanie Knopp

    Full Text Available BACKGROUND: The control of helminth infections and prevention of anemia in developing countries are of considerable public health importance. The purpose of this study was to determine patterns and risk factors of helminth infections and anemia in a rural and a peri-urban community of Zanzibar, Tanzania, in the context of national helminth control programs. METHODOLOGY/PRINCIPAL FINDINGS: We carried out a community-based cross-sectional study in 454 individuals by examining at least two stool samples with different methods for soil-transmitted helminths (Ascaris lumbricoides, hookworm, Strongyloides stercoralis, and Trichuris trichiura and one urine sample for Schistosoma haematobium. Finger-prick blood was taken to estimate anemia levels and to detect antibody reactions against ascariasis, strongyloidiasis and schistosomiasis, using an enzyme-linked immunosorbent assay (ELISA approach. Parasitological methods determined a helminth prevalence of 73.7% in the rural, and 48.9% in the peri-urban setting. Most helminth infections were of light intensity with school-aged children showing the highest intensities. Multiple helminth species infections were pervasive in rural dwellers regardless of age. More than half of the participants were anemic, with a particularly high prevalence in the peri-urban setting (64.7%. Risk factors for helminth infections were age, sex, consumption of raw vegetables or salad, recent travel history, and socio-economic status. CONCLUSION/SIGNIFICANCE: After several years of chemotherapy-based morbidity control efforts in Zanzibar, helminth prevalences are still high and anemia is common, but helminth infection intensities are low. Hence, chemotherapy should be continued, and complemented with improved access to clean water, adequate sanitation, and health education, along with poverty alleviation measures for a more enduring impact.

  2. Mass Administration of Ivermectin for the Elimination of Onchocerciasis Significantly Reduced and Maintained Low the Prevalence of Strongyloides stercoralis in Esmeraldas, Ecuador.

    Mariella Anselmi

    2015-11-01

    Full Text Available To evaluate the effect of ivermectin mass drug administration on strongyloidiasis and other soil transmitted helminthiases.We conducted a retrospective analysis of data collected in Esmeraldas (Ecuador during surveys conducted in areas where ivermectin was annually administered to the entire population for the control of onchocerciasis. Data from 5 surveys, conducted between 1990 (before the start of the distribution of ivermectin and 2013 (six years after the interruption of the intervention were analyzed. The surveys also comprised areas where ivermectin was not distributed because onchocerciasis was not endemic. Different laboratory techniques were used in the different surveys (direct fecal smear, formol-ether concentration, IFAT and IVD ELISA for Strongyloides stercoralis.In the areas where ivermectin was distributed the strongyloidiasis prevalence fell from 6.8% in 1990 to zero in 1996 and 1999. In 2013 prevalence in children was zero with stool examination and 1.3% with serology, in adult 0.7% and 2.7%. In areas not covered by ivermectin distribution the prevalence was 23.5% and 16.1% in 1996 and 1999, respectively. In 2013 the prevalence was 0.6% with fecal exam and 9.3% with serology in children and 2.3% and 17.9% in adults. Regarding other soil transmitted helminthiases: in areas where ivermectin was distributed the prevalence of T. trichiura was significantly reduced, while A. lumbricoides and hookworms were seemingly unaffected.Periodic mass distribution of ivermectin had a significant impact on the prevalence of strongyloidiasis, less on trichuriasis and apparently no effect on ascariasis and hookworm infections.

  3. Efficacy of mebendazole and levamisole, alone or in combination, for soil-transmitted helminthiasis

    Ifo Faujiah Sihite

    2014-01-01

    Full Text Available Background The World Health Organization (WHO recommends four, single-dose drugs (albendazole, levamisole, mebendazole, and pyrantel pamoate for management of soil-transmitted helminthiasis (STH. Previous studies have shown varied and inconsistent outcomes of these STH treatments. Objective To compare the efficacy of mebendazole and levamisole,alone or in combination, for the treatment of STH. Methods An open randomized controlled trial was conducted in Secanggang, North Sumatera from August to October 2009. School-aged children with STH infection were randomized into three groups. Group I received a single dose of mebendazole (500 mg; group II received a single dose of levamisole (2.5 mg/kg; and group III received a single dose of mebendazole-levamisole combined. Stool samples were collected at baseline, and the 1st, 2nd, 3rd, and 4th weeks after treatment and examined by the Kato-Katz technique. Statistical analyses were Kruskal-Wallis test for cure rate and Analysis of Variance (ANOVA test for egg reduction rate. Results STH was diagnosed in 197 children with the following parasite species: Ascariasis (96 children, 48.7%, Trichuriasis (58 children, 29.4%, and mixed infection (43 children, 21.8%. We found no hookworm infection in any of our subjects. Groups I and III had significantly higher efficacy (P=0.0001 against STH (egg reduction rate 99.3% and 99.9%; cure rate 92.2% and 98.4%, respectively at 4th week of treatment. Conclusion A single dose of mebendazole alone and combined with levamisole have better efficacy compared to a single dose of levamisole for the treatment of STH. The highest efficacy of these treatments is noted at the 4th week after drug administration. [Paediatr Indones. 2014;54:9-14.].

  4. Stunting and soil-transmitted-helminth infections among school-age pupils in rural areas of southern China

    Chen Ying-Dan

    2010-10-01

    Full Text Available Abstract Background Stunting and soil-transmitted helminth (STH infections including ascariasis, trichuriasis and hookworm remain major public health problems in school-age pupils in developing countries. The objectives of this study were to determine the prevalence of stunting for children and its association with three major soil-transmitted helminths (STH in rural areas of southern China. The study also aims to determine risk factors for stunting and to provide guidance on the prevention and control of stunting and STH infections for future studies in this field. Results A cross-sectional survey was carried out in the poor rural areas in Guangxi Autonomous Regional and Hainan Province where STH prevalence was higher between September and November 2009. Pupils were from 15 primary schools. All the school-age pupils aged between 9 and 12 years old (mean age 11.2 ± 3.2 years, from grades three to six took part in this study. Study contents include questionnaire surveys, physical examination and laboratory methods (stool checking for eggs of three major STH infections and haemoglobin determination was performed for the anaemia test. Finally 1031 school-age pupils took part in survey. The results showed that the overall prevalence of stunting (HAZ Conclusion The present study showed that stunting was highly prevalent among the study population and STH infection is one of the important risk factors for stunting, with moderate-to-heavy intensity infections being the main predictor of stunting. Hence, additional interventions measures such as to promote de-worming treatment, to enhance health education and to improve hygiene and sanitation in order to reduce stunting in this population, are needed throughout the primary school age group.

  5. Worm Infections in Children.

    Weatherhead, Jill E; Hotez, Peter J

    2015-08-01

    • On the basis of research evidence, worm infections are important global child health conditions causing chronic disability that lasts from childhood into adulthood (Table 1). (2)(3) Evidence Quality: B • On the basis of research evidence, the major worm infections found in developing countries include ascariasis, trichuriasis, hookworm infection, and schistosomiasis; toxocariasis, enterobiasis, and cysticercosis are also found in poor regions of North America and Europe. (4)(9)(13) Evidence Quality: B • On the basis of expert consensus, children and adolescents are often vulnerable to acquiring large numbers of worms, ie, high-intensity infections (Fig 1)(21)(22)(23) Evidence Quality: D • On the basis of expert consensus and research evidence, moderate and heavy worm burdens cause increased morbidity because of growth and intellectual stunting in children and adolescents. Many of these effects may result from helminth-induced malnutrition. (21)(22)(23) Evidence Quality: C • On the basis of expert consensus and research evidence, worm infections are also commonly associated with eosinophilia. (48) (49) Evidence Quality: B • On the basis of research evidence as well as consensus, helminthes can cause inflammation in the lung (asthma), gastrointestinal tract (enteritis and colitis), liver (hepatitis and fibrosis), and urogenital tract. (7)(21)(22)(23)(27)(28)(40)(41)(43) Evidence Quality: B • On the basis of research evidence, microscopy techniques for diagnosis of worm infections in children often exhibit suboptimal sensitivities and specificities, necessitating new or improved diagnostic modalities such as polymerase chain reaction. (54)(55) Evidence Quality: A • On the basis of research evidence and expert consensus, mass drug administration (“preventive chemotherapy”) has becomea standard practice for ministries of health in low- and middle-income countries to control intestinal helminth infections and schistosomiasis. (67)(68) Evidence

  6. Compliance with anthelmintic treatment in the neglected tropical diseases control programmes: a systematic review.

    Shuford, Kathryn V; Turner, Hugo C; Anderson, Roy M

    2016-01-01

    Preventive chemotherapy (PCT) programmes are used to control five of the highest burden neglected tropical diseases (NTDs): soil-transmitted helminth infections (hookworm, ascariasis, and trichuriasis), lymphatic filariasis, schistosomiasis, onchocerciasis, and trachoma. Over the past decade, new resource commitments for the NTDs have enabled such programmes to intensify their control efforts, and for some diseases, to shift from goals of morbidity control to the interruption of transmission and elimination. To successfully eliminate the parasite reservoir, these programmes will undoubtedly require prolonged, high treatment coverage. However, it is important to consider that even when coverage levels reach an acceptable proportion of the target population, there may be a considerable gap between coverage (those who receive the drug) and compliance (those who actually consume the drug)-a topic of fundamental and perhaps underestimated importance. We conducted a systematic review of published literature that investigated compliance to PCT programmes for NTD control and elimination. Databases searched included PubMed/Medline, Web of Knowledge (including Web of Science), OVID, and Scopus. Data were collected on compliance rates, reasons for non-compliance, as well as the heterogeneity of compliance definitions and calculations across programmes and studies. A total of 112 studies were selected for inclusion. The findings of the review revealed substantial heterogeneity across compliance terms and definitions; an imbalance of available studies for particular disease areas and countries; and finally, a lack of longitudinal compliance studies to properly investigate the role of systematic non-compliance. The lack of consistency among reporting of compliance data can result in under- or over-estimating compliance in a population, and therefore has serious implications for setting and reaching elimination targets. Reframing of the guidelines on compliance definitions

  7. "PYOGENIC LIVER ABSCESS IN CHILDREN: A LONG TIME HOSPITAL EXPERIENCE"

    G. Khotaii

    2004-05-01

    Full Text Available Consensus regarding management of pyogenic liver abscess (PLA among children is yet to emerge, and documentation on these subjects is scanty. Eighteen cases of PLA admitted at Children’s Medical Center in Tehran, Iran, over a 15 year period were analyzed to document the clinical profile and to evaluate the management of PLA among children. Records of all patients were reviewed for presenting signs and symptoms, any associated condition, investigative results, management, and follow–up findings. The overall rate of PLA was 48.9 per 100,000 pediatric admissions in our hospital. Moderate to severe malnutrition was present in five (27.8% and ascariasis in seven (38.9% children. Common presentations were fever (100%, abdominal pain (76.9%, and tender hepatomegaly (83.3%. Fourteen patients (77.8% had solitary liver abscess. Organism was isolated in 11 cases (63.3%, and staphylococcus aureus was the commonest isolate (66.7%.Twelve cases were managed conservatively with antibiotics alone, of these only two (16.7% required drainage later. Percutaneous aspiration was also undertaken in four additional (22.2% cases and open drainage in two (11.1%, at presentation. The overall mortality rate was 11.1%. Time taken for complete resolution ranged from 10 to 40 days. Altogether, we conclude that any child presenting with fever, abdominal pain, and tender hepatomegaly should be subjected to ultrasound scan for early detection of PLA. It seems that a combination of cloxacillin and gentamicin or a third generation cephalosporine and gentamicin, especially in infants, is a satistactory initial coverage. Therapeutic drainage is not an obligation in all cases of PLA. When required, percutaneous needle aspiration is safe and effective. Resolution and significant reduction in mortality has been made possible by early detection and appropriate antibiotic therapy.

  8. Preparation and Identification of a Human Single Chain Fv Antibody Against Ascaris lumbricoides%抗蛔虫人源单链抗体库的构建及鉴定

    何光志; 田维毅; 高英; 王平; 王文佳; 奚锦; 俞琦; 王乾宇; 黄高

    2011-01-01

    Objective To construct humanize phage antibody library against Ascaris lumbricoides and to screen specificity scFv to Ascaris lumbricoides. Methods Total RNA was abstracted from peripheral blood lympho-cytes of 20 persons, and was used to amplify VH and VL gene by RT-PCR. The amplified VH and VL genes were spliced to form scFv gene which was cloned into pCANTAB-SE phagemid, and the constructed recombinant phage-mid was transformed to E. Coli TC1 to construct human natural single-chain antibody library from which positive clones were screened. Results A primary library of 1.5 × 106 and a second library of 1.2 × 106 were constructed. Conclusion This study was to provide us the basis for radionuclide imaging and therapy for ascariasis.%目的:构建抗蛔虫人源单链抗体库,从中筛选建抗蛔虫人源特异性单链抗体.方法:分离10个患蛔虫病人的淋巴细胞,提取总RNA反转录为cDNA,PCR扩增人抗体重链(VH)和轻链(VL)可变区基因,采用SOE-PCR法将VH和VL片段随机拼接成scFv片段,并克隆入噬菌粒载体pCANTAB5E中,构建噬菌体单链抗体库.结果:初级库库容量为1.8×106,在大肠杆菌TG1中重组后得到1.6×106的次级抗体库.结论:本研究成功构建抗蛔虫人源单链抗体库,拟在为蛔虫病的预防、诊断、治疗奠定基础.

  9. Effect of Ascaris lumbricoides infection on T helper cell type 2 in rural Egyptian children.

    Shalaby, Naglaa M; Shalaby, Nehad M

    2016-01-01

    Ascaris lumbricoides is a neglected parasite that induces changes in host immune response. This study is conducted to define the serum levels of tumor necrosis factor alpha (TNF-α), interleukin-4 (IL-4), and interleukin-5 (IL-5) in some Egyptian children and their relations to intensity of infection, age, and ascariasis symptoms. Stool samples were examined using formol-ether concentration and Kato-Katz thick smear techniques. Sera of 60 A. lumbricoides-infected children and 20 controls were tested by enzyme-linked immunosorbent assay. The mean sera concentrations of TNF-α, IL-4, and IL-5 were 7.41±2.5 pg/mL, 107.60±18.3 pg/mL, and 389.52±28.0 pg/mL, respectively. The controls had mean serum TNF-α 7.10±2.4 pg/mL, IL-4 25.49±2.6 pg/mL, and IL-5 88.76±22.7 pg/mL. The difference in the concentration of sera cytokines was statistically significant for IL-4 and IL-5 (Plumbricoides-infected children and controls. The intensity of infection correlated positively with IL-4 and IL-5 at r=0.959 and r=0.919, respectively. The concentrations of IL-4 and IL-5 correlated positively with the age at r=0.845 and r=0.934, respectively. Asthma and gastrointestinal tract upsets were correlated positively with IL-4 and IL-5. These data indicate that A. lumbricoides infection in our locality is associated with significantly high levels of IL-4 and IL-5. PMID:27022269

  10. A scoping review and prevalence analysis of soil-transmitted helminth infections in Honduras.

    Ana Lourdes Sanchez

    Full Text Available BACKGROUND: Honduras is endemic for soil-transmitted helminth (STH infections, but critical information gaps still remain on the prevalence and intensity of these infections as well as on their spatial distribution at subnational levels. OBJECTIVES: Firstly, to review the research activity on STH infections in Honduras and secondly, to carry out a national prevalence analysis and map the geographical distribution of these infections in children. METHODS: A systematic search was conducted of the published and grey literature to identify scientific work on the impact and prevalence of STH infections done between May 1930 and June 30, 2012. International databases and Honduran journals were searched. Grey literature was gleaned from local libraries and key informants. Select studies conducted between 2001 and 2012 were used to produce prevalence maps and to investigate association between STH prevalence and socio-economic and environmental factors. RESULTS: Of 257 identified studies, 211 (21.4% peer-reviewed were retained for analysis and categorized as clinical research (10.9%, treatment efficacy studies (8.1% or epidemiological studies (81%. Prevalence analysis and geographical mapping included 36 epidemiological studies from Honduras's 18 departments and 23% of its municipalities. Overall STH prevalence was >50% in 40.6% of municipalities. Prevalences above 20% for each trichuriasis, ascariasis, and hookworm infection were found in 68%, 47.8%, and 7.2% of studied municipalities, respectively. Municipalities with lower human development index, less access to of potable water, and with higher annual precipitation showed higher STH prevalences. CONCLUSIONS: This is the first study to provide a comprehensive historic review of STH research activity and prevalence in Honduras, revealing important knowledge gaps related to infection risk factors, disease burden, and anti-parasitic drug efficacy, among others. Our decade-long prevalence analysis

  11. Productivity Loss Related to Neglected Tropical Diseases Eligible for Preventive Chemotherapy: A Systematic Literature Review

    Rijnsburger, Adriana J.; Severens, Johan L.

    2016-01-01

    Background Neglected Tropical Diseases (NTDs) not only cause health and life expectancy loss, but can also lead to economic consequences including reduced ability to work. This article describes a systematic literature review of the effect on the economic productivity of individuals affected by one of the five worldwide most prevalent NTDs: lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminths (ascariasis, trichuriasis, and hookworm infection) and trachoma. These diseases are eligible to preventive chemotherapy (PCT). Methodology/Principal Findings Eleven bibliographic databases were searched using different names of all NTDs and various keywords relating to productivity. Additional references were identified through reference lists from relevant papers. Of the 5316 unique publications found in the database searches, thirteen papers were identified for lymphatic filariasis, ten for onchocerciasis, eleven for schistosomiasis, six for soil-transmitted helminths and three for trachoma. Besides the scarcity in publications reporting the degree of productivity loss, this review revealed large variation in the estimated productivity loss related to these NTDs. Conclusions It is clear that productivity is affected by NTDs, although the actual impact depends on the type and severity of the NTD as well as on the context where the disease occurs. The largest impact on productivity loss of individuals affected by one of these diseases seems to be due to blindness from onchocerciasis and severe schistosomiasis manifestations; productivity loss due to trachoma-related blindness has never been studied directly. However, productivity loss at an individual level might differ from productivity loss at a population level because of differences in the prevalence of NTDs. Variation in estimated productivity loss between and within diseases is caused by differences in research methods and setting. Publications should provide enough information to enable

  12. Individual predisposition, household clustering and risk factors for human infection with Ascaris lumbricoides: new epidemiological insights.

    Martin Walker

    Full Text Available BACKGROUND: Much of our current understanding of the epidemiology of Ascaris lumbricoides infections in humans has been acquired by analyzing worm count data. These data are collected by treating infected individuals with anthelmintics so that worms are expelled intact from the gastrointestinal tract. Analysis of such data established that individuals are predisposed to infection with few or many worms and members of the same household tend to harbor similar numbers of worms. These effects, known respectively as individual predisposition and household clustering, are considered characteristic of the epidemiology of ascariasis. The mechanisms behind these phenomena, however, remain unclear. In particular, the impact of heterogeneous individual exposures to infectious stages has not been thoroughly explored. METHODOLOGY/PRINCIPAL FINDINGS: Bayesian methods were used to fit a three-level hierarchical statistical model to A. lumbricoides worm counts derived from a three-round chemo-expulsion study carried out in Dhaka, Bangladesh. The effects of individual predisposition, household clustering and household covariates of the numbers of worms per host (worm burden were considered simultaneously. Individual predisposition was found to be of limited epidemiological significance once household clustering had been accounted for. The degree of intra-household variability among worm burdens was found to be reduced by approximately 58% when household covariates were included in the model. Covariates relating to decreased affluence and quality of housing construction were associated with a statistically significant increase in worm burden. CONCLUSIONS/SIGNIFICANCE: Heterogeneities in the exposure of individuals to infectious eggs have an important role in the epidemiology of A. lumbricoides infection. The household covariates identified as being associated with worm burden provide valuable insights into the source of these heterogeneities although above all

  13. 误诊为急性结石性胆囊炎31例病例分析%The analysis of misdiagnosed as acute calculos cholecystitis in 31 cases.

    陈永友

    2012-01-01

    Objective To analyze and explore the causes of misdiagnosed as acute calculos cholecystitis. Methods Thirty - one cases misdiagnosed as acute calculous cholecystitis in our hospital from July 2000 to May 2012 were retrospectively analyzed and summarized. Results Thirty - one patients with cholecystolithiasis were misdiagnosed as acute calculous cholecystitis, The final diagnosis of misdiagnosis cases: 6 cases of acute myocardial infarction , 5 cases of herpes zoster, 4 cases of carcinoma of gallbladder, 3 cases of high - position appendicitis, 2 cases of pancreatitis, 2 cases of pneumonia, 2 cases of colon tumor, 2 cases of upper digestive tract perforation, 2 cases of renal calculus, 1 case of dissection of aorta, 1 case of pleuritis, 1 case of ascariasis of biliary tract. Conclusion Dont detailed inquest the case history, examine the body carelessly, lack of relevant knowledge and experience, ignoring the other disease diagnosis while gallstones found were the main causes of misdiagnosis.%目的 分析、总结其他疾病误诊为急性结石性胆囊炎的原因,积累经验.方法 对2000年7月至2012 年5月收治的31例临床误诊为急性结石性胆囊炎病例进行回顾性分析、总结.结果 31例患者均因原有胆囊结石而误诊为急性结石性胆囊炎.误诊疾病的最终诊断为:急性心肌梗死6例(19.35%),带状疱疹5例(16.13%),胆囊癌4例(12.9%),高位阑尾炎3例(9.68%),胰腺炎2例(6.45%),肺炎2例(6.45%),结肠肿瘤2例(6.45%),上消化道穿孔2例(6.45%),右肾结石2例(6.45%),主动脉夹层1例(3.22%),胸膜炎1例(3.22%),胆道蛔虫1例(3.22%).结论询问病史不详细、查体不仔细、缺少对相关疾病鉴别诊断的知识和经验、发现胆囊结石而忽略其它疾病诊断是造成误诊的主要原因.

  14. The clinical and radiological observation of endoscopic retrograde cholangiopancreatography

    Park, Choong Shik; Park, Byoung Lan; Chun, Hyun Woo; Kim, Byung Geun; Park, Hong Bae [Kwangju Christian Hospital, Kwangju (Korea, Republic of)

    1981-12-15

    of ascariasis, 1 case of clonorchiasis with cholangitis, 1 case of clonorchiasis with stone, 2 cases of C.B.D. ca. 2 cases of G. B. ca, 3 cases of intrahepatic disease, 1 case of stones in the biliary tree with ampullary ca. 6. Complications of ERCP and ERPP were extremely rare. Transient abdominal distention, abdominal discomfort and elevated serum amylase were noted, but were not clinically significant.

  15. Effect of Ascaris lumbricoides infection on T helper cell type 2 in rural Egyptian children

    Shalaby NM

    2016-03-01

    Full Text Available Naglaa M Shalaby,1 Nehad M Shalaby2 1Department of Parasitology, Faculty of Medicine, 2Mansoura University Children Hospital, Mansoura University, Mansoura, Egypt Abstract: Ascaris lumbricoides is a neglected parasite that induces changes in host immune response. This study is conducted to define the serum levels of tumor necrosis factor alpha (TNF-α, interleukin-4 (IL-4, and interleukin-5 (IL-5 in some Egyptian children and their relations to intensity of infection, age, and ascariasis symptoms. Stool samples were examined using formol-ether concentration and Kato-Katz thick smear techniques. Sera of 60 A. lumbricoides-infected children and 20 controls were tested by enzyme-linked immunosorbent assay. The mean sera concentrations of TNF-α, IL-4, and IL-5 were 7.41±2.5 pg/mL, 107.60±18.3 pg/mL, and 389.52±28.0 pg/mL, respectively. The controls had mean serum TNF-α 7.10±2.4 pg/mL, IL-4 25.49±2.6 pg/mL, and IL-5 88.76±22.7 pg/mL. The difference in the concentration of sera cytokines was statistically significant for IL-4 and IL-5 (P<0.01 between A. lumbricoides-infected children and controls. The intensity of infection correlated positively with IL-4 and IL-5 at r=0.959 and r=0.919, respectively. The concentrations of IL-4 and IL-5 correlated positively with the age at r=0.845 and r=0.934, respectively. Asthma and gastrointestinal tract upsets were correlated positively with IL-4 and IL-5. These data indicate that A. lumbricoides infection in our locality is associated with significantly high levels of IL-4 and IL-5.Keywords: Ascaris lumbricoides, children, rural, Egypt, IL-4, IL-5, TNF-α

  16. The clinical and radiological observation of endoscopic retrograde cholangiopancreatography

    of ascariasis, 1 case of clonorchiasis with cholangitis, 1 case of clonorchiasis with stone, 2 cases of C.B.D. ca. 2 cases of G. B. ca, 3 cases of intrahepatic disease, 1 case of stones in the biliary tree with ampullary ca. 6. Complications of ERCP and ERPP were extremely rare. Transient abdominal distention, abdominal discomfort and elevated serum amylase were noted, but were not clinically significant

  17. Helminthiases in Montes Claros. Preliminary survey

    Rina Girard Kaminsky

    1976-04-01

    Full Text Available A preliminary survey was conducted for the presence of helminths in the city of Montes Claros, M. G., Brazil. Three groups of persons were examined by the direct smear, Kato thick film and MIFC techniques; one group by direct smear and Kato only. General findings were: a high prevalence of hookworm, followed by ascariasis, S. mansoni, S. stercoralis and very light infections with T. trichiurá. E. vermicularis and H. nana were ranking parasites at an orphanage, with some hookworm and S. mansoni infections as well. At a pig slaughter house, the dominant parasites were hookworm and S. mansoni. Pig cysticercosis was an incidental finding worth mentioning for the health hazard it represents for humans as well as an economic loss. From the comparative results between the Kato and the MIF the former proved itself again as a more sensitive and reliable concentration method for helminth eggs, of low cost and easy performance.Um estudo preliminar sobre helmintos foi feito na cidade de Montes Claros, MG, Brasil. Três grupos de pessoas foram examinados pelos métodos direto, de Kato e do MIF e um grupo pelos métodos direto e Kato exclusivamente. Encontrou-se uma alta prevalência de necatorose, seguindo-se ascaríase, S. mansoni, S. stercoralis, e infecções leves pelo T. trichiura. E. vermicularis e H. nana foram osparasitos mais prevalentes num orfanato, com alguns casos de infecção pelo Necator e S. mansoni. Cisticercose dos suinos foi achado incidental e é importante ser mencionada devido ao perigo que representa no plano da Saúde Pública, bem como pela perda econômica que produz. Discutiu-se brevemente a importância do solo na transmissão dos helmintos num clima quente e seco. Da comparação dos métodos de Kato e MIF, o primeiro demonstrou ser o método mais sensível para ovos de helmintos, de baixo custo e fácil preparo.

  18. Serum cytokines profiles in Nigerian children withAscaris lumbricoides infection

    Irior Dominic Osagie; Abu Maliki

    2010-01-01

    Objective:To investigate the cytokines profile in the serum of some Nigerian children with Ascaris lumbricoides (A. lumbricoides) infection and relations between the intensity of infection, age and the concentration of these cytokines.Methods: Feacal samples from consenting children were examined using formol ether concentration techniques and Kato-Katz thick smear technique. Sera of 96 children comprising 76A. lumbricoides infection and 20 controls were subjected to enzymes-linked immunosorbent assay.Results: The mean sera concentration of tumor necrosis factor alpha (TNF-α), interleukin-4 (IL-4), interleukin-5 (IL-5), interleukin-10 (IL-10) were (16.7±7.6) pg/mL, (4.6±0.8)pg/mL, (391.6±52.0) pg/mL and (181.2±30.4) pg/mL, respectively. The control subjects had the following mean serum cytokines: TNF-α(2.9±1.8) pg/m, IL-4 (4.0±0.1) pg/mL, IL-5 (125.1±50.1) pg/mL, IL-10 (74.5±54.2) pg/mL, respectively. The difference between the sera cytokines concentration of theA. lumbricoides infected children and their controls were statistically significant for TNF-α, IL- 5 and IL-10(χ2= 9.99,P< 0.05;χ2 = 137.24,P < 0.05;χ2 = 44.30,P < 0.05, respectively). The intensity of infection correlated positively with TNF-α, and IL-5 (r = 0.93 and 0.98, respectively) while IL-4 and IL- 10 correlated negatively with the intensity of infection (r = -0.62 and 0.99, respectively). TNF-α, IL-4 and IL-5 correlated positively with age (r = 0.19, 0.33 and 0. 66, respectively). The mean cytokines between those with mild and moderate infections were statistically significant for TNF-α, IL-5 and IL-10 (χ2 = 3.60, 4.52 and 5.30, respectively). The ratio of TNF-α: IL-10 was 0.092.Conclusions: Elevated IL-5, IL-10 and TNF-α found in the sera of the volunteers with Ascariasis implicates these cytokines as key mediators in the host responses toA. lumbriocoides infection in our studied area.

  19. Mass treatment for intestinal helminthisis control in an Amazonian endemic area in Brazil Tratamento em massa para controle das helmintíases intestinais em área endêmica na Amazônia Brasileira

    Márcio Neves Bóia

    2006-08-01

    Full Text Available The objective of the present study was to estimate the prevalence of soil-transmitted helminthiasis and evaluate the sanitary conditions and the role of a mass treatment campaign for control of these infections in Santa Isabel do Rio Negro. A cross-sectional survey was carried out in 2002, to obtain data related to the sanitary conditions of the population and fecal samples for parasitological examination in 308 individuals, followed by a mass treatment with albendazole or mebendazole with coverage of 83% of the city population in 2003. A new survey was carried out in 2004, involving 214 individuals, for comparison of the prevalences of intestinal parasitosis before and after the mass treatment. The prevalences of ascariasis, trichuriasis and hookworm infection were 48%; 27% and 21% respectively in 2002. There was a significant decrease for the frequency of infections by Ascaris lumbricoides (p O presente trabalho objetivou avaliar a prevalência e o papel de um tratamento em massa das helmintíases intestinais em Santa Isabel do Rio Negro, Estado do Amazonas, Brasil. Foi realizado em 2002 um estudo seccional, incluindo inquérito copro-parasitológico, objetivando a obtenção das prevalências das parasitoses intestinais e dados sobre as condições sanitárias do local, estudando-se uma amostra de 308 indivíduos. Em 2003 foi realizada intervenção para tratamento em massa das helmintíases intestinais com administração de albendazol (ou mebendazol para crianças entre 12 e 24 meses na sede do município, alcançando-se 83% de cobertura. Novo inquérito copro-parasitológico foi realizado em 2004, para comparação das prevalências antes a após o tratamento. As prevalências das infecções por Ascaris lumbricoides, Trichuris trichiura e ancilostomídeos foram 48%, 27% e 21%, respectivamente em 2002. Em 2004 observou-se redução significativa das infecções por Ascaris lumbricoides (p < 0,05; OR / 95% IC = 0,44 / 0,30 - 0,65, Trichuris

  20. A Proteomic Investigation of Hepatic Resistance to Ascaris in a Murine Model.

    Deslyper, Gwendoline; Colgan, Thomas J; Cooper, Andrew J R; Holland, Celia V; Carolan, James C

    2016-08-01

    The helminth Ascaris causes ascariasis in both humans and pigs. Humans, especially children, experience significant morbidity including respiratory complications, growth deficits and intestinal obstruction. Given that 800 million people worldwide are infected by Ascaris, this represents a significant global public health concern. The severity of the symptoms and associated morbidity are related to the parasite burden and not all hosts are infected equally. While the pathology of the disease has been extensively examined, our understanding of the molecular mechanisms underlying resistance and susceptibility to this nematode infection is poor. In order to investigate host differences associated with heavy and light parasite burden, an experimental murine model was developed utilising Ascaris-susceptible and -resistant mice strains, C57BL/6J and CBA/Ca, respectively, which experience differential burdens of migratory Ascaris larvae in the host lungs. Previous studies identified the liver as the site where this difference in susceptibility occurs. Using a label free quantitative proteomic approach, we analysed the hepatic proteomes of day four post infection C57BL/6J and CBA/Ca mice with and without Ascaris infection to identify proteins changes potentially linked to both resistance and susceptibility amongst the two strains, respectively. Over 3000 proteins were identified in total and clear intrinsic differences were elucidated between the two strains. These included a higher abundance of mitochondrial proteins, particularly those associated with the oxidative phosphorylation pathway and reactive oxygen species (ROS) production in the relatively resistant CBA/Ca mice. We hypothesise that the increased ROS levels associated with higher levels of mitochondrial activity results in a highly oxidative cellular environment that has a dramatic effect on the nematode's ability to successfully sustain a parasitic association with its resistant host. Under infection, both

  1. Ação terapêutica do mebendazole (R 17635 em pacientes poliparasitados: resultados finais

    Dirceu Wagner Carvalho de Souza

    1973-08-01

    lumbricoides, Enterobius vermicularis, Taenia sp, and Trichuris trichiura. Mebendazole (R 17635 was given in lOOmg tablets, one 30 minutes before breakfast and another three hours after dinner, for three consecutive days, independently of body weight. No evidence was observed of either immediate or late side effects of the ãrug. To determine parasitological cure, the Willis anã the Hoffman-Pons & Janer techniques were performed on the 7th, 14th, and 21st days after completion of treatment. In addition, in patients with taeniasis and/or enterobiasis, the "anal-swab" method was used for 7 consecutive days, beginning the 7th day after completion of treatment. Cure rates were as follows: enterobiasis, 100%; ascariasis and trichuriasis, 98%; hookworm, 94.5%. Out of 9 patients with taeniasis, 8 were cured; nevertheless, the Authors stress the necessity of larger studies, both technically and statistically, to determine the true efficacy of this drug against Taenia sp.

  2. Granulomatous peritonitis due to Ascaris lumbricoides. Case report Granulomatosis peritoneal por Ascaris lumbricoides.Presentación de un caso

    Carlos Aguirre Muñoz

    2008-06-01

    Full Text Available

    Ascariasis is one of the most prevalent and widespread human helminthic infections, especially in children of

  3. Mechanism of four regulating-intestines prescriptions in the treatment of ulcerative colitis%理肠四方治疗溃疡性结肠炎的病机

    范恒; 邱明义; 梅家俊; 沈关心; 刘松林

    2006-01-01

    息痢"范畴,其病机与乌梅丸的主治相一致,其他三方与之不完全一致,所以乌梅丸是治疗溃疡性结肠炎最有效的方剂.中医辨证施治是取得最佳疗效的前提,动物实验的造模必须符合中医证型.%AIM: To analyze curative effect of four regulating-intestines prescriptions (Wumei Wan, Baitouweng Tang, Shenling Baizhu San and Tongxie Yao-fang) on the treatment of ulcerative colitis (UC) through summing up the previous animal experimental results.METHODS: We collected the conclusions in the papers related to four regulating-intestines prescriptions for the treatment of UC which were published recently, made comparisons from the aspectsof symptoms, physical sign, pathological change, cytokine and its protein expression, blood adhesion molecule, cell apoptosis and controlling gene and analyzed the pathogenesis of UC and action mechanism of four regulating-intestines prescriptions. Four regulating-intestines prescriptions included Wumei Wan,Baitouweng Tang, Shenling Baizhu San and Tongxie Yaofang. Wumei Wan is from Treatise on Exogenous Febrile Diseases and Synopsis of the Golden Chamber, which consists of dark plum, asarum herb, dried ginger, Chinese goldthread, Chinese angelica root, aconite root, pricklyash peel, cassia twig,ginseng (sun-dried ginseng) and bark of cork tree and has marked effect in treating colic caused by ascariasis and persistent dysentery. Baitouweng Tang, from Treatise on Exogenous Febrile Diseases, consists of medicinal herbs such as pulsatilla root, Chinese goldthread, bark of cork tree and ash bark, which has functions of clearing away the heat-evil, expelling superficial evils and relieving dysentery. In addition, it has marked effect in treating heat-type dysentery. Shenling Baizhu San, from Prescriptions of Peaceful benevolent Dispensary, consists of medicinal herbs such as pulp of lotus seed, coix seed, amomum fruit, balloon flower root, white hyacinth bean, poria, ginseng (sun-dried ginseng