Institute of Scientific and Technical Information of China (English)
王川; 亢渝俊; 姜政; 王丕龙
2012-01-01
Objective To transform human aquaglyceroporin 9(AQP9) recombinant eukaryotic expression plasmid pEGFP Nl AQP9 and interference plasmid pshRNA AQP9 into attenuated Salmonella strain SL7207 by electroporation and detect their ex pression,in order to lay the foundation for elucidating the human AQP9 in pathogenesis of nonalcoholic fatty liver disease (NAFLD). Methods AQP9 gene was obtained by RT PCR from human hepatic tissue and cloned into pEGFP Nl vector,recombi nant eukaryotic expression plasmid pEGFP Nl AQP9 was constructed,designed and synthesized human AQP9 SiRNA,annealed to double stranded ShRNA, inserted to pGenesil 1 plasmid, interference plasmid pshRNA AQP9 was constructed, and then trans formed into attenuated Salmonella strain SL7207 by electroporation,the expression were detected by PCR and Western Blot,and we detected their stability. Results Recombinant plasmid pEGFP Nl AQP9 and pshRNA AQP9 were constructed, transformed into attenuated Salmonella strain SL7207,after transformed into SL7207,could express in recombinant Salmonella. Conclusion Recom binant Salmonella SL7207/pEGFP Nl AQP9 and SL7207/pshRNA AQP9 are successfully constructed,lay the foundation for fur ther study on the gene therapy of NAFLD with AQP9.%目的 将人水甘油通道蛋白9(AQP9)真核表达质粒pEGFP-N1-AQP9及干扰质粒pshRNA-AQP9通过电穿孔转化减毒沙门菌株SL7207,并验证其表达情况,为阐明AQP9在非酒精性脂肪肝病(NAFLD)中的作用奠定基础.方法 从人肝脏组织中通过RT-PCR获得AQP9基因,克隆到载体pEGFP-N1上,构建真核表达质粒pEGFP-N1-AQP9,设计合成针对人AQP9的siRNA,退火形成双链shRNA,并插入pGenesil-1质粒中,构建干扰质粒pshRNA-AQP9,电穿孔转化减毒沙门菌株SL7207,通过PCR、Western blot验证其表达情况,并检测其稳定性.结果 成功构建pEGFP-N1-AQP9及pshRNA-AQP9重组质粒,将其转化SL7207后,能在重组沙门菌中表达.结论 成功构建SL7207/pEGFP-N1-AQP9及SL7207/pshRNA-AQP
Aquaglyceroporins serve as metabolic gateways in adiposity and insulin resistance control
Rodriguez, A.; Catalan, V.; Gomez-Ambrosi, J.; Frühbeck, G.
2011-01-01
Aquaglyceroporins (AQP3, AQP7, AQP9 and AQP10) encompass a subfamily of aquaporins that allow the movement of water and other small solutes, especially glycerol, through cell membranes. Adipose tissue constitutes a major source of glycerol via AQP7. We have recently reported that, in addition to the well-known expression of AQP7 in adipose tissue, AQP3 and AQP9 are also expressed in omental and subcutaneous fat depots. Moreover, insulin and leptin act as regulators of aquaglyceroporins throug...
Expression and clinical significance of aquaglyceroporins in human hepatocellular carcinoma.
Chen, Xiao-Feng; Li, Chuan-Fei; Lü, Lin; Mei, Zhe-Chuan
2016-06-01
Aquaglyceroporins (AQPs) are a subset of the aquaporin family, and are permeable to water and glycerol. The aim of the present study was to determine the expression and clinical significance of three AQPs, AQP3, 7 and 9 in hepatocellular carcinoma (HCC). Fresh HCC and adjacent non‑tumorous liver tissues were collected from 68 patients diagnosed with HCC. The expression levels of AQP3, 7 and 9 were detected by reverse transcription‑quantitative polymerase chain reaction, western blotting and immunohistochemical analysis. The association between the expression of AQPs and clinicopathological parameters of HCC were investigated. Compared with non‑tumorous liver tissue, HCC tissues exhibited a significant (P<0.05) increase in the expression of AQP3 and a concomitant reduction in the expression levels of AQP7 and AQP9, at both the mRNA and protein levels. Immunohistochemistry revealed that AQP9 was dominantly localized on the plasma membrane of hepatocytes, while AQP3 and AQP7 exhibited a predominantly cytoplasmic and nuclear distribution. High expression of AQP3 was significantly (P<0.05) associated with low expression levels of AQP7 and AQP9. High expression of AQP3 was correlated with tumor grade (P=0.017), tumor stage (P=0.010) and lymphatic metastasis (P=0.031). Low expression of AQP7 was correlated with tumor grade (P=0.043). AQP3 was upregulated, and AQP7 and AQP9 were downregulated in HCC. A high expression of AQP3 and low expression of AQP7 was significantly associated with the aggressive features of HCC. PMID:27121567
Hepatic AQP9 expression in male rats is reduced in response to PPARα agonist treatment.
Lebeck, Janne; Cheema, Muhammad Umar; Skowronski, Mariusz T; Nielsen, Søren; Praetorius, Jeppe
2015-02-01
The peroxisome proliferator receptor α (PPARα) is a key regulator of the hepatic response to fasting with effects on both lipid and carbohydrate metabolism. A role in hepatic glycerol metabolism has also been found; however, the results are somewhat contradictive. Aquaporin 9 (AQP9) is a pore-forming transmembrane protein that facilitates hepatic uptake of glycerol. Its expression is inversely regulated by insulin in male rodents, with increased expression during fasting. Previous results indicate that PPARα plays a crucial role in the induction of AQP9 mRNA during fasting. In the present study, we use PPARα agonists to explore the effect of PPARα activation on hepatic AQP9 expression and on the abundance of enzymes involved in glycerol metabolism using both in vivo and in vitro systems. In male rats with free access to food, treatment with the PPARα agonist WY 14643 (3 mg·kg(-1)·day(-1)) caused a 50% reduction in hepatic AQP9 abundance with the effect being restricted to AQP9 expressed in periportal hepatocytes. The pharmacological activation of PPARα had no effect on the abundance of GlyK, whereas it caused an increased expression of hepatic GPD1, GPAT1, and L-FABP protein. In WIF-B9 and HepG2 hepatocytes, both WY 14643 and another PPARα agonist GW 7647 reduced the abundance of AQP9 protein. In conclusion, pharmacological PPARα activation results in a marked reduction in the abundance of AQP9 in periportal hepatocytes. Together with the effect on the enzymatic apparatus for glycerol metabolism, our results suggest that PPARα activation in the fed state directs glycerol into glycerolipid synthesis rather than into de novo synthesis of glucose. PMID:25477377
Charakterisierung des Burkholderia cenocepacia Aquaglyceroporins
Wree, Dorothea
2010-01-01
In der vorliegenden Arbeit wurde ein Aquaglyceroporin des Krankenhausproblemkeims Burkholderia cenocepacia, BccGlpF, charakterisiert. Unter besonderer Beobachtung stand die Struktur-Funktionsbeziehung der eigentlich kochkonservierten NPA-Motive.
Aquaglyceroporins: ancient channels for metalloids
Bhattacharjee, Hiranmoy; Mukhopadhyay, Rita; Thiyagarajan, Saravanamuthu; Rosen, Barry P.
2008-01-01
The identification of aquaglyceroporins as uptake channels for arsenic and antimony shows how these toxic elements can enter the food chain, and suggests that food plants could be genetically modified to exclude arsenic while still accumulating boron and silicon.
Mammalian aquaglyceroporin function in metabolism.
Laforenza, Umberto; Bottino, Cinzia; Gastaldi, Giulia
2016-01-01
Aquaglyceroporins are integral membrane proteins that are permeable to glycerol as well as water. The movement of glycerol from a tissue/organ to the plasma and vice versa requires the presence of different aquaglyceroporins that can regulate the entrance or the exit of glycerol across the plasma membrane. Actually, different aquaglyceroporins have been discovered in the adipose tissue, small intestine, liver, kidney, heart, skeletal muscle, endocrine pancreas and capillary endothelium, and their differential expression could be related to obesity and the type 2 diabetes. Here we describe the expression and function of different aquaglyceroporins in physiological condition and in obesity and type 2 diabetes, suggesting they are potential therapeutic targets for metabolic disorders. PMID:26456554
DEFF Research Database (Denmark)
Spegel, Peter; Chawade, Aakash; Nielsen, Søren;
2015-01-01
profiling did not detect differential gene expression between genotypes. Metabolite profiling revealed a sex independent increase in plasma glycerol (+55%) and glucose (+24%), and reduction in threonate (all at q < 0.1) in Aqp9(-/-) db/db mice compared to controls. Metabolite profiling thus confirms a role......Deletion of the glycerol channel aquaporin-9 (Aqp9) reduces postprandial blood glucose levels in leptin receptor-deficient (db/db) obese mice on a C57BL/6 × C57BLKS mixed genetic background. Furthermore, shRNA-mediated reduction of Aqp9 expression reduces liver triacylglycerol (TAG) accumulation in...... observed elevated plasma glucose in Aqp9(-/-) db/db mice (+1.1 mmol/L, life-time average), while plasma insulin concentration was reduced at the time of death. Glucose levels changed similarly in pentobarbital anesthetized, glucagon challenged Aqp9(wt) db/db and Aqp9(-/-) db/db mice. Liver transcriptional...
Institute of Scientific and Technical Information of China (English)
田培超; 王怀立; 罗强; 禚志红
2008-01-01
Objective To investigate the expression of aquaporin-9(AQP-9)in the brain tissue of rats with infectious brain edema and explore the role of AQP-9 in the oecurrgnce and progression of the brain edema. Methods A total of 128 normal 1-month-old SD rats weighing 70-100 g of either sex were randomly divided into two equal groups, namely the normal saline(NS) group and lipopolysaecharide(LPS)group.Acute infectious brain edema was induced in rats in the LPS group by injecting LPS via the left internal carotid artery,and the rats in the NS groups received NS injection.At 6,12,24 and 48 h after the injection,the brain tissue was taken from the rats to observe the histopathology by Hernatoxylin-Eosin Stain and lneasure the brain water content(BWC).The permeability of the blood-brain barrier of the rats was tested using Evans blue(EB)method.The expressions of AQP-9 protein and mRNA in the brain tissue Were detected using immunohistochemistry and RT-PCR,respectively. Results InLPS group,the space around the blood vessels was obviously broadened in the brain tissue,where inflammatory cell infiltration,glioeyte swelling,vacuolar degeneration of the neurons and neuronal nuclear shrinkage were seen.At 6,12,24,and 48 h following LPS or NS injection,the BWC,EB content,and expressions of AQP-9 protein and mRNA in the LPS group were all significantly higher than those in the NS group(P<0.05),In the LPS group,positive correlations were found between BWC and EB content,AQP-9 protein expression and BWC,AQP一9 mRNA and BWC,AQP-9mR.NA and EBcontent,and between AQP-9 protein andmRNA.Conclusion AQP-9 might participate in occurrcnce and development of infectious brain edema in rats,it might be positive correlation.%目的 探讨水通道蛋白-9(AQP-9)在内毒素脂多糖(LPS)致大鼠感染性脑水肿脑组织中的表达及意义. 方法 1月龄普通级SD大鼠128只采用随机数字表法分为生理盐水(NS)组(64只)和LPS组(64只),采用颈内动脉注射LPS制作大鼠感染
Aquaglyceroporins in the kidney: present state of knowledge and prospects.
Michalek, K
2016-04-01
Aquaporins belong to a family of small, transmembrane proteins that form channels selectively permeable for water. Some of them known as aquaglyceroporins also enable transportation of other small molecules such as glycerol, urea or ammonia. To date, 13 isoforms of aquaporins has been discovered in mammals (AQP0 - AQP12), 9 of which is localized in different parts of the renal tubular epithelium. In recent years, particular interest has been paid to aquaporins selectively permeable only to water molecules, determination of their localization and expression allowed to define the role of these proteins in renal excretion of water and their importance in the development of diseases. Alas, thus far the role in the physiological processes of the aquaglyceroporins localized in the kidneys has not been fully determined. This review summarizes our current knowledge on additional transport functions of renal AQPs (AQP3, AQP6, AQP7 and AQP8). On the basis of the information gathered and the opinions by many authors, it has been found that aquaglyceroporins are most probably the key element in the renal regulation of nitrogen balance and maintenance of the correct pH of body fluids. Elucidating additional transport functions of AQPs in the kidney will improve our understanding of the renal function in heath and diseases. The presented in this article prospect on renal aquaglyceroporin hopefully will stimulate future research in both basic and clinical fields. PMID:27226178
Sabir, Farzana; Loureiro-Dias, Maria C; Prista, Catarina
2016-05-01
Efficient homeostasis of water and glycerol is a prerequisite for osmoregulation and other aspects of yeasts life. The cellular status of these molecules is often associated with functional presence of aquaporins and aquaglyceroporins. The present study provides a detailed updated analysis of aquaporins and aquaglyceroporins in 47 yeast species. A comprehensive analysis of aquaporins and aquaglyceroporins in 38 strains of Saccharomyces cerevisiae from different ecological niches is also presented. The functionality of specific aquaporins in yeasts has been associated with their adaptation requirements in different environmental conditions. In the present study, various inactivating mutations in aquaporin sequences were found in strains of S. cerevisiae Likewise, several new interesting polymorphisms in aquaglyceroporin sequences of some commercial wine and brewing strains, vineyard and bakery strains were also observed. Conceivably, both in the case of aquaporins and aquaglyceroporins inactivating mutations resulted in competitive advantage in selected environments. Topology and conservation of important regulatory residues within all sequences are also analyzed. We expect that the present review may contribute to establish the functional relevance of aquaporins/aquaglyceroporins for various aspects of yeasts physiology. PMID:27001976
Song, Jie; Baker, Nicola; Rothert, Monja; Henke, Björn; Jeacock, Laura; Horn, David; Beitz, Eric
2016-02-01
The chemotherapeutic arsenal against human African trypanosomiasis, sleeping sickness, is limited and can cause severe, often fatal, side effects. One of the classic and most widely used drugs is pentamidine, an aromatic diamidine compound introduced in the 1940s. Recently, a genome-wide loss-of-function screen and a subsequently generated trypanosome knockout strain revealed a specific aquaglyceroporin, TbAQP2, to be required for high-affinity uptake of pentamidine. Yet, the underlying mechanism remained unclear. Here, we show that TbAQP2 is not a direct transporter for the di-basic, positively charged pentamidine. Even though one of the two common cation filters of aquaglyceroporins, i.e. the aromatic/arginine selectivity filter, is unconventional in TbAQP2, positively charged compounds are still excluded from passing the channel. We found, instead, that the unique selectivity filter layout renders pentamidine a nanomolar inhibitor of TbAQP2 glycerol permeability. Full, non-covalent inhibition of an aqua(glycero)porin in the nanomolar range has not been achieved before. The remarkable affinity derives from an electrostatic interaction with Asp265 and shielding from water as shown by structure-function evaluation and point mutation of Asp265. Exchange of the preceding Leu264 to arginine abolished pentamidine-binding and parasites expressing this mutant were pentamidine-resistant. Our results indicate that TbAQP2 is a high-affinity receptor for pentamidine. Taken together with localization of TbAQP2 in the flagellar pocket of bloodstream trypanosomes, we propose that pentamidine uptake is by endocytosis. PMID:26828608
Directory of Open Access Journals (Sweden)
Jie Song
2016-02-01
Full Text Available The chemotherapeutic arsenal against human African trypanosomiasis, sleeping sickness, is limited and can cause severe, often fatal, side effects. One of the classic and most widely used drugs is pentamidine, an aromatic diamidine compound introduced in the 1940s. Recently, a genome-wide loss-of-function screen and a subsequently generated trypanosome knockout strain revealed a specific aquaglyceroporin, TbAQP2, to be required for high-affinity uptake of pentamidine. Yet, the underlying mechanism remained unclear. Here, we show that TbAQP2 is not a direct transporter for the di-basic, positively charged pentamidine. Even though one of the two common cation filters of aquaglyceroporins, i.e. the aromatic/arginine selectivity filter, is unconventional in TbAQP2, positively charged compounds are still excluded from passing the channel. We found, instead, that the unique selectivity filter layout renders pentamidine a nanomolar inhibitor of TbAQP2 glycerol permeability. Full, non-covalent inhibition of an aqua(glyceroporin in the nanomolar range has not been achieved before. The remarkable affinity derives from an electrostatic interaction with Asp265 and shielding from water as shown by structure-function evaluation and point mutation of Asp265. Exchange of the preceding Leu264 to arginine abolished pentamidine-binding and parasites expressing this mutant were pentamidine-resistant. Our results indicate that TbAQP2 is a high-affinity receptor for pentamidine. Taken together with localization of TbAQP2 in the flagellar pocket of bloodstream trypanosomes, we propose that pentamidine uptake is by endocytosis.
Mikhailov, Andrei
2004-01-01
Single trace operators with the large R-charge in supersymmetric Yang-Mills theory correspond to the null-surfaces in $AdS_5\\times S^5$. We argue that the moduli space of the null-surfaces is the space of contours in the super-Grassmanian parametrizing the complex $(2|2)$-dimensional subspaces of the complex $(4|4)$-dimensional space. The odd coordinates on this super-Grassmanian correspond to the fermionic degrees of freedom of the superstring.
Modulation of activity of the adipocyte aquaglyceroporin channel by plant extracts.
Cals-Grierson, M-M
2007-02-01
The plasma membrane protein, aquaglyceroporin-7 (AQP7) is exclusively expressed in adipocytes and appears to be a channel for glycerol entry and exit. It is possible that by facilitating the opening of these channels, the loss of intracellular glycerol could be encouraged and thus reduce the size of the lipid reservoir. Human preadipocytes and mouse 3T3-L1 preadipocytes were induced to develop an adipocytic phenotype by culture in a semi-defined medium. After 7 days, the expression of AQP7 message had increased by 37-fold, a level which could be further up-regulated by troglitazone or retinoic acid or down-regulated by insulin. The mature adipocytes also expressed immunoreactive aquaporin (AQP) channel protein as assessed by immunocytochemistry and Western blot. The addition of adrenaline to the culture medium stimulated the release of glycerol (blockable by HgCl(2)). Plant extracts, with potential anti-cellulite properties, were tested for their effect on glycerol elimination. These included wild yam root (Dioscorea opposita), cocoa bean (Theobroma cacao), horse chestnut tree (Aesculus hippocastanum) seed and bark and tomato (Solanum lycopersicum). Of these, D. opposita appeared to induce a dose-dependent glycerol release. The results show that our assay can help to identify modulators of AQP7 channel expression and activation in adipocytes. PMID:18489306
Liu, Xiao-Dan; Wei, Yi; Zhou, Xiao-Yang; Pei, Xue; Zhang, Shi-Hong
2015-10-01
Aquaglyceroporins (GlpFs) that transport glycerol along with water and other uncharged solutes are involved in osmoregulation in myriad species. Fungal species form a large group of eukaryotic organisms, and their GlpFs may be diverse, exhibiting various activities. However, few filamentous fungal GlpFs have been biologically investigated. Here, a glpF gene from the halophilic fungus Aspergillus glaucus (AgglpF) was verified to be a channel of water or glycerol in Xenopus laevis oocytes and was further functionally analyzed in three heterologous systems. In Saccharomyces cerevisiae, cells overexpressing AgglpF possessed significant tolerance of drought, salt, and certain metal ions. AgglpF was then characterized in the filamentous fungus of Neurospora crassa. Based on the N. crassa aquaporin gene (NcAQP) disruption mutant (the Δaqp mutant), a series of complementary strains carrying NcAQP and AgglpF and three asparagine-proline-alanine-gene (NPA)-deleted AgglpF fragments were created. As revealed by salt resistance analysis, the AgglpF complementary strain possessed the highest salt resistance among the tested strains. In addition, the intracellular glycerol content in the AgglpF complementary strain was markedly higher than that in the other strains. The AgGlpF-green fluorescent protein (GFP) fusion protein was subcellularly localized in the plasma membrane of onion epidermal cells, suggesting that AgglpF functions in plants. Indeed, when AgglpF was expressed in Arabidopsis thaliana, transgenic lines survived under conditions of high osmotic stress and under conditions of drought stress in particular. Overall, our results revealed that AgGlpF as a water/glycerol transporter is required for survival of both fungi and plants under conditions of high osmotic stress and may have value in applications in genetic engineering for generating high salt and drought resistance. PMID:26209670
Identification of key residues involved in Si transport by the aquaglyceroporins.
Carpentier, Gabriel A; Garneau, Alexandre P; Marcoux, Andrée-Anne; Noël, Micheline; Frenette-Cotton, Rachelle; Isenring, Paul
2016-09-01
We recently demonstrated that the aquaglyceroporins (AQGPs) could act as potent transporters for orthosilicic acid (H4SiO4). Although interesting, this finding raised the question of whether water and H4SiO4, the transportable form of Si, permeate AQGPs by interacting with the same region of the pore, especially in view of the difference in molecular radius between the two substrates. Here, our goal was to identify residues that endow the AQGPs with the ability to facilitate Si diffusion by examining the transport characteristics of mutants in which residues were interchanged between a water-permeable but Si-impermeable channel (aquaporin 1 [AQP1]) and a Si-permeable but water-impermeable channel (AQP10). Our results indicate that the composition of the arginine filter (XX/R), known to include three residues that play an important role in water transport, may also be involved in Si selectivity. Interchanging the identities of the nonarginine residues within this filter causes Si transport to increase by approximately sevenfold in AQP1 and to decrease by approximately threefold in AQP10, whereas water transport and channel expression remain unaffected. Our results further indicate that two additional residues in the AQP arginine filter may be involved in substrate selectivity: replacing one of the residues has a profound effect on water permeability, and replacing the other has a profound effect on Si permeability. This study has thus led to the identification of residues that could play a key role in Si transport by the AQGPs and shown that substrate selectivity is likely ensured by more than one checkpoint within or near the pore. PMID:27527099
Müller-Lucks, Annika; Gena, Patrizia; Frascaria, Daniele; Altamura, Nicola; Svelto, Maria; Beitz, Eric; Calamita, Giuseppe
2013-06-25
Understanding the selectivity of aquaporin (AQP) membrane channels and exploiting their biotechnological potential will require structural and functional studies of wild type and modified proteins; however, expression systems have not previously yielded AQPs in the necessary milligrams quantities. Cell free (CF) systems have emerged in recent years as fast, efficient and versatile technologies for the production of high quality membrane proteins. Here, we establish a convenient method to synthesize large amounts of functional human aquaglyceroporin 3 protein (AQP3), an AQP of physiological relevance conducting glycerol and some small neutral solutes besides water. Milligram amounts of AQP3 were produced as a histidine-tagged protein (hAQP3-6His) in an Escherichia coli extract-based CF system in the presence of the non-ionic detergent Brij-98. The recombinant AQP3 was purified by affinity chromatography, incorporated into liposomes and evaluated functionally by stopped-flow light scattering. Correct protein folding was indicated by the high glycerol and water permeability exhibited by the hAQP3-6His proteoliposomes as compared to empty control liposomes. Functionality of hAQP3-6His was further confirmed by the strong inhibition of the glycerol and water permeability by phloretin and HgCl2, respectively, two blockers of AQP3. Fast and convenient CF production of functional AQP3 may serve as basis for further structural/functional assessment of aquaglyceroporins and help boosting the AQP-based biomimetic technologies. PMID:23541697
Gravitational action with null boundaries
Lehner, Luis; Poisson, Eric; Sorkin, Rafael D
2016-01-01
We present a complete discussion of the boundary term in the action functional of general relativity when the boundary includes null segments in addition to the more usual timelike and spacelike segments. We confirm that ambiguities appear in the contribution from a null segment, because it depends on an arbitrary choice of parametrization for the generators. We also show that similar ambiguities appear in the contribution from a codimension-two surface at which a null segment is joined to another (spacelike, timelike, or null) segment. The parametrization ambiguity can be tamed by insisting that the null generators be affinely parametrized; this forces each null contribution to the boundary action to vanish, but leaves intact the fredom to rescale the affine parameter by a constant factor on each generator. Once a choice of parametrization is made, the ambiguity in the joint contributions can be eliminated by formulating well-motivated rules that ensure the additivity of the gravitational action. Enforcing t...
Wallace, Ian S; Roberts, Daniel M
2005-12-27
Major intrinsic proteins (MIPs) are a diverse class of integral membrane proteins that facilitate the transport of water and some small solutes across cellular membranes. X-ray structures of MIPs indicate that a tetrad of residues (the ar/R region) form a narrow pore constriction that constitutes the selectivity filter. In comparison with mammalian and microbial species, plants have a greater number and diversity of MIPs with greater than 30 genes encoding four phylogenetic subfamilies with eight different classes of ar/R sequences. The nodulin 26-like intrinsic protein (NIP) subfamily in Arabidopsis can be subdivided into two ar/R subgroups: the NIP subgroup I, which resembles the archetype of the family, soybean nodulin 26, and the NIP subgroup II, which is represented by the Arabidopsis protein AtNIP6;1. These two NIPs differ principally by the substitution of a conserved alanine (NIP subgroup II) for a conserved tryptophan (NIP subgroup I) in the helix 2 position (H2) of the ar/R filter. A comparison of the water and solute tranport properties of the two proteins was performed by expression in Xenopus laevis oocytes. Nodulin 26 is an aquaglyceroporin with a modest osmotic water permeability (P(f)) and the ability to transport uncharged solutes such as glycerol and formamide. In constrast, AtNIP6;1 showed no measurable water permeability but transported glycerol, formamide, as well as larger solutes that were impermeable to nodulin 26. By site-directed mutagenesis, we show that the H2 position is the crucial determinant that confers these transport behaviors. A comparison of the NIPs and tonoplast-intrinsic proteins (TIP) shows that the H2 residue can predict the transport profile for water and glycerol with histidine found in TIP-like aquaporins, tryptophan found in aquaglyceroporins (NIP I), and alanine found in water-impermeable glyceroporins (AtNIP6;1). PMID:16363796
Budinich, Marco
2014-01-01
We investigate the relations between spinors and null vectors in Clifford algebra with particular emphasis on the conditions that a spinor must satisfy to be simple (also: pure). In particular we prove: i) a new property for null vectors: each of them bisects spinor space into two parts of equal size; ii) that simple spinors form one-dimensional subspaces of spinor space; iii) a necessary and sufficient condition for a spinor to be simple that generalizes a theorem of Cartan and Chevalley that appears now as a corollary of this result. We also show how to write down easily the most general spinor with a given associated totally null plane.
Sormani, Christina
2015-01-01
Given a time function $\\tau$ on a spacetime $M$, we define a `null distance function', $\\hat{d}_\\tau$, built from and closely related to the causal structure of $M$. In basic models with timelike $\
Null lifts and projective dynamics
Cariglia, Marco
2015-01-01
We describe natural Hamiltonian systems using projective geometry. The null lift procedure endows the tangent bundle with a projective structure where the null Hamiltonian is identified with a projective conic and induces a Weyl geometry. Projective transformations generate a set of known and new dualities between Hamiltonian systems, as for example the phenomenon of coupling-constant metamorphosis. We conclude outlining how this construction can be extended to the quantum case for Eisenhart-Duval lifts.
Phase-Occultation Nulling Coronagraphy
Lyon, Richard G; Clampin, Mark; Petrone, Peter
2015-01-01
The search for life via characterization of earth-like planets in the habitable zone is one of the key scientific objectives in Astronomy. We describe a new phase-occulting (PO) interferometric nulling coronagraphy (NC) approach. The PO-NC approach employs beamwalk and freeform optical surfaces internal to the interferometer cavity to introduce a radially dependent plate scale difference between each interferometer arm (optical path) that nulls the central star at high contrast while transmitting the off-axis field. The design is readily implemented on segmented-mirror telescope architectures, utilizing a single nulling interferometer to achieve high throughput, a small inner working angle (IWA), sixth-order or higher starlight suppression, and full off-axis discovery space, a combination of features that other coronagraph designs generally must trade. Unlike previous NC approaches, the PO-NC approach does not require pupil shearing; this increases throughput and renders it less sensitive to on-axis common-mo...
Budinich, Marco
2014-03-01
We investigate the relations between spinors and null vectors in Clifford algebra of any dimension with particular emphasis on the conditions that a spinor must satisfy to be simple (also: pure). In particular, we prove: (i) a new property for null vectors: each of them bisects spinor space into two subspaces of equal size; (ii) that simple spinors form one-dimensional subspaces of spinor space; (iii) a necessary and sufficient condition for a spinor to be simple that generalizes a theorem of Cartan and Chevalley which becomes a corollary of this result. We also show how to write down easily the most general spinor with a given associated totally null plane. This paper is dedicated to the memory of my father Paolo Budinich who passed away in November 2013 not before transferring to me his enthusiasm for simple spinors.
Bootstrapping Null Polygon Wilson Loops
Gaiotto, Davide; Maldacena, Juan; Sever, Amit; Vieira, Pedro
2010-01-01
We derive the two loop expressions for polygonal Wilson loops by starting from the one loop expressions and applying an operator product expansion. We do this for polygonal Wilson loops in R^{1,1} and find a result in agreement with previous computations. We also discuss the spectrum of excitations around flux tube that connects two null Wilson lines.
Parasitic interference in nulling interferometry
Matter, Alexis; Danchi, William C; Lopez, Bruno; Absil, Olivier
2013-01-01
Nulling interferometry aims to detect faint objects close to bright stars. Its principle is to produce a destructive interference along the line-of-sight so that the stellar flux is rejected, while the flux of the off-axis source can be transmitted. In practice, various instrumental perturbations can degrade the nulling performance. Any imperfection in phase, amplitude, or polarization produces a spurious flux that leaks to the interferometer output and corrupts the transmitted off-axis flux. One of these instrumental pertubations is the crosstalk phenomenon, which occurs because of multiple parasitic reflections inside transmitting optics, and/or diffraction effects related to beam propagation along finite size optics. It can include a crosstalk of a beam with itself, and a mutual crosstalk between different beams. This can create a parasitic interference pattern, which degrades the intrinsic transmission map - or intensity response - of the interferometer. In this context, we describe how this instrumental ...
Balloon Exoplanet Nulling Interferometer (BENI)
Lyon, Richard G.; Clampin, Mark; Woodruff, Robert A.; Vasudevan, Gopal; Ford, Holland; Petro, Larry; Herman, Jay; Rinehart, Stephen; Carpenter, Kenneth; Marzouk, Joe
2009-01-01
We evaluate the feasibility of using a balloon-borne nulling interferometer to detect and characterize exosolar planets and debris disks. The existing instrument consists of a 3-telescope Fizeau imaging interferometer with 3 fast steering mirrors and 3 delay lines operating at 800 Hz for closed-loop control of wavefront errors and fine pointing. A compact visible nulling interferometer is under development which when coupled to the imaging interferometer would in-principle allow deep suppression of starlight. We have conducted atmospheric simulations of the environment above 100,000 feet and believe balloons are a feasible path forward towards detection and characterization of a limited set of exoplanets and their debris disks. Herein we will discuss the BENI instrument, the balloon environment and the feasibility of such as mission.
Zilberberg, Oded; Romito, Alessandro; Gefen, Yuval
2013-01-01
Weak value (WV) is a quantum mechanical measurement protocol, proposed by Aharonov, Albert, and Vaidman. It consists of a weak measurement, which is weighed in, conditional on the outcome of a later, strong measurement. Here we define another two-step measurement protocol, null weak value (NVW), and point out its advantages as compared to WV. We present two alternative derivations of NWVs and compare them to the corresponding derivations of WVs.
On the Penrose inequality along null hypersurfaces
Mars, Marc
2015-01-01
The null Penrose inequality, i.e. the Penrose inequality in terms of the Bondi energy, is studied by introducing a funtional on surfaces and studying its properties along a null hypersurface $\\Omega$ extending to past null infinity. We prove a general Penrose-type inequality which involves the limit at infinity of the Hawking energy along a specific class of geodesic foliations called Geodesic Asymptotic Bondi (GAB), which are shown to always exist. Whenever, this foliation approaches large spheres, this inequality becomes the null Penrose inequality and we recover the results of Ludvigsen-Vickers and Bergqvist. By exploiting further properties of the functional along general geodesic foliations, we introduce an approach to the null Penrose inequality called Renormalized Area Method and find a set of two conditions which implies the validity of the null Penrose inequality. One of the conditions involves a limit at infinity and the other a condition on the spacetime curvature along the flow. We investigate the...
Parasitic interference in nulling interferometry
Matter, A.; Defrère, D.; Danchi, W. C.; Lopez, B.; Absil, O.
2013-05-01
Nulling interferometry aims to detect faint objects close to bright stars. Its principle is to produce a destructive interference along the line of sight so that the stellar flux is rejected, while the flux of the off-axis source can be transmitted. In practice, various instrumental perturbations can degrade the nulling performance. Any imperfection in phase, amplitude or polarization produces a spurious flux that leaks to the interferometer output and corrupts the transmitted off-axis flux. One of these instrumental perturbations is the crosstalk phenomenon, which occurs because of multiple parasitic reflections inside transmitting optics, and/or diffraction effects related to beam propagation along finite size optics. It can include a crosstalk of a beam with itself, and a mutual crosstalk between different beams. This can create a parasitic interference pattern, which degrades the intrinsic transmission map - or intensity response - of the interferometer. In this context, we describe how this instrumental effect impairs the performance of a Bracewell interferometer. A simple formalism is developed to derive the corresponding modified intensity response of the interferometer, as a function of the two parameters of interest: the crosstalk level (or contamination rate) and the phase shift between the primary and secondary - parasitic - beams. We then apply our mathematical approach to a few scientific cases, both analytically and using the GENIESIM simulation software, adapted to handle coherent crosstalk. Our results show that a coherent crosstalk level of about 1 per cent implies a 20 per cent drop of the signal-to-noise ratio at most. Careful attention should thus be paid to reduce the crosstalk level inside an interferometric instrument and ensure an instrumental stability that provides the necessary sensitivity through calibration procedures.
Analysis of aquaporin 9 expression in human epidermis and cultured keratinocytes
Directory of Open Access Journals (Sweden)
Yoshinori Sugiyama
2014-01-01
Full Text Available Aquaporin 9 (AQP9 is a member of the aquaglyceroporin family that transports glycerol, urea and other small solutes as well as water. Compared to the expression and function in epidermal keratinocytes of AQP3, another aquaglyceroporin, our knowledge of epidermal AQP9 remains elusive. In this study, we investigated the expression of AQP9 in the human epidermis and cultured keratinocytes. Immunofluorescence studies revealed that AQP9 expression is highly restricted to the stratum granulosum of the human epidermis, where occludin is also expressed at the tight junctions. Interestingly, the AQP3 staining decreased sharply below the cell layers in which AQP9 is expressed. In cultured normal human epidermal keratinocytes (NHEK, knock-down of AQP9 expression in the differentiated cells induced by RNA interference reduced glycerol uptake, which was not as pronounced as was the case with AQP3 knock-down cells. In contrast, similar reduction of urea uptake was detected in AQP9 and AQP3 knock-down cells. These findings suggested that AQP9 expression in NHEK facilitates at least the transport of glycerol and urea. Finally, we analyzed the effect of retinoic acid (RA, a potent stimulator of keratinocyte proliferation, on AQP3 and AQP9 mRNA expression in differentiated NHEK. Stimulation with RA at 1 μM for 24 h augmented AQP3 expression and down-regulated AQP9 expression. Collectively, these results indicate that AQP9 expression in epidermal keratinocytes is regulated in a different manner from that of AQP3.
Thermodynamic origin of the null energy condition
Parikh, Maulik; Svesko, Andrew
2016-01-01
We derive the classical null energy condition, understood as a constraint on the Ricci tensor, from the second law of thermodynamics applied to Bekenstein-Hawking entropy. The derivation provides evidence that the null energy condition, which has usually been regarded as a condition on matter, is fundamentally a property of gravity.
Thermodynamic Origin of the Null Energy Condition
Parikh, Maulik
2015-01-01
We derive the classical null energy condition, understood as a constraint on the Ricci tensor, from the second law of thermodynamics applied to Bekenstein-Hawking entropy. The derivation provides evidence that the null energy condition, which has usually been regarded as a condition on matter, is fundamentally a property of gravity.
Causal cells: spacetime polytopes with null hyperfaces
Neiman, Yasha
2012-01-01
We consider polyhedra and 4-polytopes in Minkowski spacetime - in particular, null polyhedra with zero volume, and 4-polytopes that have such polyhedra as their hyperfaces. We present the basic properties of several classes of null-faced 4-polytopes: 4-simplices, "tetrahedral diamonds" and 4-parallelotopes. We propose a "most regular" representative of each class. The most-regular parallelotope is of particular interest: its edges, faces and hyperfaces are all congruent, and it features both null hyperplanes and null segments. A tiling of spacetime with copies of this polytope can be viewed alternatively as a lattice with null edges, such that each point is at the intersection of four lightrays in a tetrahedral pattern. We speculate on the relevance of this construct for discretizations of curved spacetime and for quantum gravity.
Null Subjects in European and Brazilian Portuguese
Barbosa, Pilar; Duarte, Maria Eugênia L.; Kato, Mary Aizawa
2005-01-01
The goals of this paper are twofold: a) to provide a structural account of the effects of the informal ‘Avoid Pronoun Principle’, proposed in Chomsky (1981: 65) for the Null Subject Languages (NSLs), and b) to compare, in European and Brazilian Portuguese (EP and BP), the distribution of the third person pronouns in its full and null forms, to check whether in written corpora BP incorporates signs of the ongoing loss of the null subject, largely attested in its contemporary spoken language. T...
Real null coframes in general relativity and GPS type coordinates
International Nuclear Information System (INIS)
Some time ago, Finkelstein defined a 'symmetric' null frame with four real null vectors. We discuss this Finkelstein frame and show that a similarly defined real null coframe is closely related to the GPS type coordinates recently introduced by Rovelli
High-contrast Nulling Interferometry Techniques Project
National Aeronautics and Space Administration — "We are developing rotating-baseline nulling-interferometry techniques and algorithms on the single-aperture Hale and Keck telescopes at near-infrared wavelengths,...
Null geodesics in brane world universe
International Nuclear Information System (INIS)
We study null bulk geodesic motion in the brane world cosmology in the RS2 scenario and in the static universe in the bulk of the charged topological AdS black hole. We obtain equations describing the null bulk geodesic motion as observed in one lower dimensions. We find that the null geodesic motion in the bulk of the brane world cosmology in the RS2 scenario is observed to be under the additional influence of extra non-gravitational force by the observer on the three-brane, if the brane universe does not possess the Z2 symmetry. As for the null geodesic motion in the static universe in the bulk of the charged AdS black hole, the extra force is realized even when the brane universe has the Z2 symmetry. (author)
Latex allergy and filaggrin null mutations
DEFF Research Database (Denmark)
Carlsen, Berit C; Meldgaard, Michael; Hamann, Dathan;
2011-01-01
Objectives Natural rubber latex (NRL) contains over 200 proteins of which 13 have been identified as allergens and the cause of type I latex allergy. Health care workers share a high occupational risk for developing latex allergy. Filaggrin null mutations increase the risk of type I sensitizations...... to aeroallergens and it is possible that filaggrin null mutations also increase the risk of latex allergy. The aim of this paper was to examine the association between filaggrin null mutations and type I latex allergy. Methods Twenty latex allergic and 24 non-latex allergic dentists and dental...... assistants, occupationally exposed to latex, were genotyped for filaggrin null mutations R501X and 2282del4. Latex allergy was determined by a positive reaction or a historical positive reaction to a skin prick test with NRL. Results 41 individuals were successfully genotyped. Three individuals were...
Null-sissemakse - eraisikule riskantne / Tõnu Tramm
Tramm, Tõnu, 1968-
2005-01-01
Ilmunud ka: Delovõje Vedomosti 20. apr. lk. 26. Hansaliising ja Ühisliising käivitasid kampaania, mille käigus pakutakse uusi kuni 250 000 krooni maksvaid autosid null-sissemaksega. Kommenteerib ASi SEB Ühisliising arendusdirektor Ove Muuk. Tabel: Null-sissemaksega auto tuleb kallim. Lisad: Kuidas saavutada võimalikult väike kuumakse?; Kuidas maksta võimalikult vähe intressi? Vt. samas: Argo Rebane: Liisingufirmast saab parema hinna
Computing extinction maps of star nulling interferometers
Henault, Francois
2008-01-01
Herein is discussed the performance of spaceborne nulling interferometers searching for extra-solar planets, in terms of their extinction maps projected on-sky. In particular, it is shown that the designs of Spatial Filtering (SF) and Achromatic Phase Shifter (APS) subsystems, both required to achieve planet detection and characterization, can sensibly affect the nulling maps produced by a simple Bracewell interferometer. Analytical relationships involving cross correlation products are provi...
Computing extinction maps of star nulling interferometers.
Hénault, Francois
2008-03-31
Herein is discussed the performance of spaceborne nulling interferometers searching for extra-solar planets, in terms of their extinction maps projected on-sky. In particular, it is shown that the designs of Spatial Filtering (SF) and Achromatic Phase Shifter (APS) subsystems, both required to achieve planet detection and characterization, can sensibly affect the nulling maps produced by a simple Bracewell interferometer. Analytical relationships involving cross correlation products are provided and numerical simulations are performed, demonstrating marked differences in the aspect of extinction maps and the values of attained fringes contrasts. It is concluded that depending on their basic principles and designs, FS and APS will result in variable capacities for serendipitous discoveries of planets orbiting around their parent star. The mathematical relationships presented in this paper are assumed to be general, i.e. they should apply to other types of multi-apertures nulling interferometers. PMID:18542551
Two roads to the null energy condition
Parikh, Maulik
2015-11-01
The null energy condition has sweeping consequences in general relativity. I argue here that it has been misunderstood as a property exclusively of matter, when in fact it arises only in a theory of both matter and gravity. I then derive an equivalent geometric formulation of the null energy condition from worldsheet string theory, where it arises beautifully as simple Einstein’s equations in two dimensions. But further, I show that this condition also has a thermodynamic origin, following from a local version of the second law of thermodynamics, applied to gravitational entropy. Thus, far from being an incidental property of matter, the validity of the null energy condition hints at the deep dual origins of gravity.
Two Roads to the Null Energy Condition
Parikh, Maulik
2015-01-01
The null energy condition has sweeping consequences in general relativity. I argue here that it has been misunderstood as a property exclusively of matter, when in fact it arises only in a theory of both matter and gravity. I then derive an equivalent geometric formulation of the null energy condition from worldsheet string theory, where it arises beautifully as simply Einstein's equations in two dimensions. But further, I show that this condition also has a thermodynamic origin, following from a local version of the second law of thermodynamics, applied to gravitational entropy. Thus, far from being an incidental property of matter, the validity of the null energy condition hints at the deep dual origins of gravity.
Supersymmteric Null-like Holographic Cosmologies
Lin, Feng-Li; Wen, Wen-Yu
2006-01-01
We construct a new class of 1/4-BPS time dependent domain-wall solutions with null-like metric and dilaton in type II supergravities, which admit a null-like big bang singularity. Based on the domain-wall/QFT correspondence, these solutions are dual to 1/4-supersymmetric quantum field theories living on a boundary cosmological background with time dependent coupling constant and UV cutoff. In particular we evaluate the holographic $c$ function for the 2-dimensional dual field theory living on...
The Null Energy Condition and its violation
Rubakov, V. A.
2014-01-01
We give a mini-review of scalar field theories with second-derivative Lagrangians, whose field equations are second order. Some of these theories admit solutions violating the Null Energy Condition and having no obvious pathologies. We give a few examples of using these theories in cosmological setting and also in the context of the creation of a universe in the laboratory.
A Philosophical Critique of Null Hypothesis Testing.
Orey III, Michael A.; And Others
1989-01-01
An attempt is made to clarify the philosophical foundations of the debate over research methodology appropriate for psychology in particular and the utility of null hypothesis testing in general. The article also relates the debate to education and suggests that the debate is far from settled. (IAH)
Gravitational collapse of a cylindrical null shell in vacuum
Directory of Open Access Journals (Sweden)
S. Khakshournia
2008-03-01
Full Text Available Barrabès-Israel null shell formalism is used to study the gravitational collapse of a thin cylindrical null shell in vacuum. In general the lightlike matter shell whose history coincides with a null hypersurface is characterized by a surface energy density. In addition, a gravitational impulsive wave is present on this null hypersurface whose generators admit both the shear and expansion. In the case of imposing the cylindrical flatness the surface energy-momentum tensor of the matter shell on the null hypersurface vanishes and the null hyper- surface is just the history of the gravitational wave .
Broadband nulling behaviour of PSR B2319+60
Gajjar, Vishal; Kramer, M
2012-01-01
Pulse nulling is one of many single pulse phenomena exhibited by radio pulsars. The broadband nature of this phenomena remained unexplained due to lack of coordinated observations. We are reporting broadband nulling behaviour of a well known nulling pulsar PSR B2319+60. The simultaneous observations were carried out at four different frequencies using the Giant Meterwave Radio telescope (325 and 610 MHz), the Westerbork Synthesis Radio Telescope (1420 MHz) and the Effelsberg radio telescope (5100 MHz). The nulling fractions were estimated at all four observed frequencies, which suggest similar degree of nulling across these frequencies. To comment on the broadband behaviour of pulse nulling, we calculated the Pearson cross-correlation coefficients for the occurrence of null and burst pulses between all four frequencies. We conclude that nulling is largely a broadband phenomenon for this pulsar and it points towards a global failure of the magnetospheric currents which produces radio emission at these frequenc...
The spacetime geometry of a null electromagnetic field
International Nuclear Information System (INIS)
We give a set of local geometric conditions on a spacetime metric which are necessary and sufficient for it to be a null electrovacuum, that is, the metric is part of a solution to the Einstein–Maxwell equations with a null electromagnetic field. These conditions are restrictions on a null congruence canonically constructed from the spacetime metric, and can involve up to five derivatives of the metric. The null electrovacuum conditions are counterparts of the Rainich conditions, which geometrically characterize non-null electrovacua. Given a spacetime satisfying the conditions for a null electrovacuum, a straightforward procedure builds the null electromagnetic field from the metric. Null electrovacuum geometry is illustrated using some pure radiation spacetimes taken from the literature. (paper)
Motion Behavior of Null Space in Redundant Robotic Manipulators
Shibata, Tsuyoshi; Murakami, Toshiyuki
2008-01-01
This chapter shows the control design of null space motion by PID controller. When the work space observer is emplyed in work space controller, work space and null space motion are determined independently. Then the PD based work space controller makes work space motion stable, but global stability of null space motion is not always guranteed. To improve the stability and the robustness of null space motion, PID controller considering passivity is useful and the design strategy of PID control...
On the null origin of the ambitwistor string
Casali, Eduardo; Tourkine, Piotr
2016-01-01
In this paper we present the null string origin of the ambitwistor string. Classically, the null string is the tensionless limit of string theory, and so too is the Ambitwistor string. Both have as constraint algebra the Galilean Conformal Algebra in two dimensions. But something interesting happens in the quantum theory since there is an ambiguity in quantizing the null string. We show that, given a particular choice of quantization scheme and a particular gauge, the null string coincides wi...
String spectra near some null cosmological singularities
Madhu, Kallingalthodi; Narayan, K.
2009-01-01
We construct cosmological spacetimes with null Kasner-like singularities as purely gravitational solutions with no other background fields turned on. These can be recast as anisotropic plane-wave spacetimes by coordinate transformations. We analyse string quantization to find the spectrum of string modes in these backgrounds. The classical string modes can be solved for exactly in these time-dependent backgrounds, which enables a detailed study of the near singularity string spectrum, (time-d...
Renormalization of null Wilson lines in EQCD
International Nuclear Information System (INIS)
Radiation and energy loss of a light, high-energy parton in a perturbative Quark-Gluon Plasma is controlled by transverse momentum exchange. The troublesome infrared contributions to transverse momentum exchange can be computed on the lattice using dimensional reduction to EQCD. However a novel extended operator, the Null Wilson Line of EQCD, is involved. We compute the renormalization properties of this object’s lattice implementation to next-to-leading order, which should facilitate its efficient calculation on the lattice
PHASE CLOSURE NULLING: THEORY AND PRACTICE
Directory of Open Access Journals (Sweden)
A. Chelli
2009-01-01
Full Text Available We provide a complete theory of the phase closure of a binary system in which a small, feeble, and unresolved companion acts as a perturbing parameter on the spatial frequency spectrum of a dominant, bright, resolved source. We demonstrate that the in uence of the companion can be measured with precision by measuring the phase closure of the system near the nulls of the primary visibility function. In these regions of phase closure nulling, frequency intervals always exist where the phase closure signature of the companion is larger than any systematic error and can thus be measured. We show that this technique allows retrieval of many astrophysically relevant properties of faint and close companions such as ux, position, and in favorable cases, spectrum. As a proof of concept, using the AMBER/VLTI instrument with 3 auxiliary telescopes of 1.8 m and only 15 minutes of on-sky integration, we detected the ve magnitudes fainter companion of HD 59717 at only 3.5 stellar radii distance from the primary. This is one of the highest contrast detected by interferometry between a companion and its parent star. We conclude by a rapid study of the potentialities of phase closure nulling observations with current interferometers and explore the requirements for a new type of dedicated instrument.
Real null coframes in general relativity and GPS type coordinates
Blagojevic, M; Hehl, F W; Obukhov, Yu N; Obukhov, Yu.N.
2002-01-01
Some time ago, D. Finkelstein defined a `symmetric' null frame with {\\it four real null vectors}. We discuss this Finkelstein frame and show that a similarly defined real null coframe is closely related to the GPS type coordinates recently introduced by Rovelli.
A Conformal Extension Theorem based on Null Conformal Geodesics
Lübbe, Christian
2008-01-01
In this article we describe the formulation of null geodesics as null conformal geodesics and their description in the tractor formalism. A conformal extension theorem through an isotropic singularity is proven by requiring the boundedness of the tractor curvature and its derivatives to sufficient order along a congruence of null conformal geodesic. This article extends earlier work by Tod and Luebbe.
Null conformal Killing-Yano tensors and Birkhoff theorem
Ferrando, Joan Josep
2015-01-01
We study the space-times admitting a null conformal Killing-Yano tensor whose divergence defines a Killing vector. We analyze the similitudes and differences with the recently studied non null case (Gen. Relativ. Grav. (2015) {\\bf 47} 1911). The results by Barnes concerning the Birkhoff theorem for the case of null orbits are analyzed and generalized.
Null conformal Killing-Yano tensors and Birkhoff theorem
Ferrando, Joan Josep; Sáez, Juan Antonio
2016-04-01
We study the space-times admitting a null conformal Killing-Yano tensor whose divergence defines a Killing vector. We analyze the similarities and differences with the recently studied non null case (Ferrando and Sáez in Gen Relativ Gravit 47:1911, 2015). The results by Barnes concerning the Birkhoff theorem for the case of null orbits are analyzed and generalized.
A Nulling Coronagraph for TPF-C
Shao, Michael; Levine, Bruce Martin; Wallace, James Kent; Orton, Glenn S.; Schmidtlin, Edouard; Lane, Benjamin F.; Seager, Sara; Tolls, Volker; Lyon, Richard G.; Samuele, Rocco; Tenerelli, Domenick J.; Woodruff, Robert; Ge, Jian
2006-01-01
The nulling coronagraph is one of 5 instrument concepts selected by NASA for study for potential use in the TPF-C mission. This concept for extreme starlight suppression has two major components, a nulling interferometer to suppress the starlight to 10(sup -10) per airy spot within 2 (lamda)/D of the star, and a calibration interferometer to measure the residual scattered starlight. The ability to work at 2 (lamda)/D dramatically improves the science throughput of a space based coronagraph like TPF-C. The calibration interferometer is an equally important part of the starlight suppression system. It measures the measures the wavefront of the scattered starlight with very high SNR, to 0.05nm in less than 5 minutes on a 5mag star. In addition, the post coronagraph wavefront sensor will be used to measure the residual scattered light after the coronagraph and subtract it in post processing to 12x10(sup -11) to enable detection of an Earthlike planet with a SNR of 510.
Null Geodesics in Five Dimensional Manifolds
Seahra, S S; Seahra, Sanjeev S.; Wesson, Paul S.
2001-01-01
We analyze a class of 5D non-compact warped-product spaces characterized by metrics that depend on the extra coordinate via a conformal factor. Our model is closely related to the so-called canonical coordinate gauge of Mashhoon et al. We confirm that if the 5D manifold in our model is Ricci-flat, then there is an induced cosmological constant in the 4D sub-manifold. We derive the general form of the 5D Killing vectors and relate them to the 4D Killing vectors of the embedded spacetime. We then study the 5D null geodesic paths and show that the 4D part of the motion can be timelike --- that is, massless particles in 5D can be massive in 4D. We find that if the null trajectories are affinely parameterized in 5D, then the particle is subject to an anomalous acceleration or fifth force. However, this force may be removed by reparameterization, which brings the correct definition of the proper time into question. Physical properties of the geodesics --- such as rest mass variations induced by a variable cosmologi...
Quasilocal energy exchange and the null cone
Uzun, Nezihe
2016-01-01
Energy is at best defined quasilocally in general relativity. Quasilocal energy definitions depend on the conditions one imposes on the boundary Hamiltonian, i.e., how a finite region of spacetime is "isolated". Here, we propose a method to define and investigate systems in terms of their matter plus gravitational energy content. We adopt a generic construction, that involves embedding of an arbitrary dimensional worldsheet into an arbitrary dimensional spacetime, to a 2 + 2 picture. In our case, the closed 2-dimensional spacelike surface $\\mathbb{S}$, that is orthogonal to the 2-dimensional timelike worldsheet $\\mathbb{T}$ at every point, encloses the system in question. The integrability conditions of $\\mathbb{T}$ and $\\mathbb{S}$ correspond to three null tetrad gauge conditions once we transform our notation to the one of the null cone observables. We interpret the Raychaudhuri equation of $\\mathbb{T}$ as a work-energy relation for systems that are not in equilibrium with their surroundings. We achieve thi...
Peculiar nulling in PSR J1738-2330
Gajjar, Vishal; Krämer, M
2009-01-01
Several pulsars show sudden cessation of pulsed emission, which is known as nulling. The number of known nulling pulsars has not been significantly enhanced in the last decade, although the pulsar population has more than doubled following the Parkes multi-beam pulsar survey. A systematic follow-up study of the new pulsars, discovered in this survey, is being carried out by us at 325-MHz with GMRT. The peculiar nulling behaviour of PSR J1738-2330, observed as a part of this 325-MHz GMRT survey, is reported in this paper. The pulsar appears to show a periodic null-burst cycle with an upper limit to nulling fraction, of about 90 percent. The pulsed flux density declines by a factor 94 during the nulled pulses in this pulsar.
On the null origin of the ambitwistor string
Casali, Eduardo
2016-01-01
In this paper we present the null string origin of the ambitwistor string. Classically, the null string is the tensionless limit of string theory, and so too is the Ambitwistor string. Both have as constraint algebra the Galilean Conformal Algebra in two dimensions. But something interesting happens in the quantum theory since there is an ambiguity in quantizing the null string. We show that, given a particular choice of quantization scheme and a particular gauge, the null string coincides with the ambitwistor string both classically and quantum mechanically. We also show that the same holds for the spinning versions of the null string and Ambitwistor string. With these results we clarify the relationship between the Ambitwistor string, the null string, the usual string and the Hohm-Siegel-Zwiebach theory.
On the Local Extension of the Future Null Infinity
Li, Junbin; Zhu, Xi-Ping
2014-01-01
We consider a characteristic problem of the vacuum Einstein equations with part of the initial data given on a future complete null cone with suitable decay, and show that the solution exists uniformly around the null cone for general such initial data. We can then define a segment of the future null infinity. The initial data are not required to be small and the decaying condition inherits from the works of \\cite{Ch-K} and \\cite{K-N}.
Null subjects and agreement marks in European and Brazilian Portuguese
Duarte, Maria Eugênia Lammoglia; Varejão, Filomena
2013-01-01
The purpose of this article is to discuss the relation between the presence of agreement marks and null subjects in contemporary European and Brazilian Portuguese based on very recent samples of speech collected in Lisbon and Rio de Janeiro. In order to bring additional evidence to support the analysis, we will briefly review the issues involving the Null Subject in Romance Languages and some diachronic and synchronic analyses which distinguish Brazilian and European Portuguese as far as null...
Are Null Results Becoming an Endangered Species in Marketing?
Raymond Hubbard; JS Armstrong
1992-01-01
Editorial procedures in the social and biomedical sciences are said to promote studies that falsely reject the null hypothesis. This problem may also exist in major marketing journals. Of 692 papers using statistical significance tests sampled from the Journal of Marketing, Journal of Marketing Research, and Journal of Consumer Research between 1974 and 1989, only 7.8% failed to reject the null hypothesis. The percentage of null results declined by one-half from the 1970s to the 1980s. The...
String spectra near some null cosmological singularities
International Nuclear Information System (INIS)
We construct cosmological spacetimes with null Kasner-like singularities as purely gravitational solutions with no other background fields turned on. These can be recast as anisotropic plane-wave spacetimes by coordinate transformations. We analyze string quantization to find the spectrum of string modes in these backgrounds. The classical string modes can be solved for exactly in these time-dependent backgrounds, which enables a detailed study of the near-singularity string spectrum, (time-dependent) oscillator masses, and wave functions. We find that for low-lying string modes (finite oscillation number), the classical near-singularity string mode functions are nondivergent for various families of singularities. Furthermore, for any infinitesimal regularization of the vicinity of the singularity, we find a tower of string modes of ultrahigh oscillation number which propagate essentially freely in the background. The resulting picture suggests that string interactions are non-negligible near the singularity.
Null radiation zone at the LHC
Hagiwara, Kaoru
2012-01-01
The null radiation zone theorem states that, when special kinematical conditions are satisfied, all the helicity amplitudes of a parton-level subprocess where a vector current is emitted vanish due to destructive interference among different diagrams. We study the manifestation of the theorem in $pp$ collisions at the $\\sqrt{s}=8$ TeV LHC. The theorem predicts that the cross section for $p p \\rightarrow j j \\gamma$ events is suppressed when the transverse momenta of the two jets are similar and when the rapidity difference between the photon and the cluster of the jets is nearly zero, because the $u u \\rightarrow u u \\gamma$ subprocess, which dominates in events with large $j j \\gamma$ invaraint mass, has strong destructive interference in this region. We confirm this prediction by the calculation with MadGraph 5, and show that the suppression on the $p p \\rightarrow j j \\gamma$ cross section is observable at the LHC.
Blob dynamics in TORPEX poloidal null configurations
Shanahan, Brendan
2016-01-01
Three dimensional blob dynamics are simulated in X-point magnetic configurations in the TORPEX device via a non-field-aligned coordinate system, using an isothermal model which evolves density, vorticity, parallel velocity and parallel current density. By modifying the parallel gradient operator to include perpendicular perturbations from poloidal field coils, numerical singularities associated with field aligned coordinates are avoided. Blobs are found to propagate according to the sheath-connected scaling, and a validation with experiment is performed. It is determined that the null region can cause an acceleration of filaments due to increasing connection length, but this accleration is small relative to other effects, which we quantify. A comparison with a previously developed analytical model is performed and an agreement is found with minimal modification. Experimental measurements are reproduced, and the dominant acceleration mechanism is identified as that of a developing dipole in a moving background...
Wormholes minimally violating the null energy condition
Bouhmadi-Lopez, Mariam; Martin-Moruno, Prado
2014-01-01
We consider novel wormhole solutions supported by a matter content that minimally violates the null energy condition. More specifically, we consider an equation of state in which the sum of the energy density and radial pressure is proportional to a constant with a value smaller than that of the inverse area characterising the system, i.e., the area of the wormhole mouth. This approach is motivated by a recently proposed cosmological event, denoted "the little sibling of the big rip", where the Hubble rate and the scale factor blow up but the cosmic derivative of the Hubble rate does not [1]. By using the cut-and-paste approach, we match interior spherically symmetric wormhole solutions to an exterior Schwarzschild geometry, and analyze the stability of the thin-shell to linearized spherically symmetric perturbations around static solutions, by choosing suitable properties for the exotic material residing on the junction interface radius. Furthermore, we also consider an inhomogeneous generalisation of the eq...
Visual and Plastic Arts in Teaching Literacy: Null Curricula?
Wakeland, Robin Gay
2010-01-01
Visual and plastic arts in contemporary literacy instruction equal null curricula. Studies show that painting and sculpture facilitate teaching reading and writing (literacy), yet such pedagogy has not been formally adopted into USA curriculum. An example of null curriculum can be found in late 19th - early 20th century education the USA…
Magnetic null points in kinetic simulations of space plasmas
Olshevsky, Vyacheslav; Divin, Andrey; Peng, Ivy Bo; Markidis, Stefano; Innocenti, Maria Elena; Cazzola, Emanuele; Lapenta, Giovanni
2015-01-01
We present a systematic attempt to study magnetic null points and the associated magnetic energy conversion in kinetic Particle-in-Cell simulations of various plasma configurations. We address three-dimensional simulations performed with the semi-implicit kinetic electromagnetic code iPic3D in different setups: variations of a Harris current sheet, dipolar and quadrupolar magnetospheres interacting with the solar wind; and a relaxing turbulent configuration with multiple null points. Spiral nulls are more likely created in space plasmas: in all our simulations except lunar magnetic anomaly and quadrupolar mini-magnetosphere the number of spiral nulls prevails over the number of radial nulls by a factor of 3-9. We show that often magnetic nulls do not indicate the regions of intensive energy dissipation. Energy dissipation events caused by topological bifurcations at radial nulls are rather rare and short-lived. The so-called X-lines formed by the radial nulls in the Harris current sheet and lunar magnetic ano...
Null Arguments in the Yoruba Child’s Early Speech
Directory of Open Access Journals (Sweden)
Bolanle Elizabeth Arokoyo
2012-09-01
Full Text Available This paper studied null arguments in the early speech of the Yoruba child. We examined whether null subjects are more prominent than null objects and whether the usage of null subjects decreases with language development in the early utterance of the Yoruba child. We also examined the relationship between argument ellipses and finiteness. Minimalist Programme was adopted as the theoretical framework because of its provision for minimality in the processes of language acquisition. The database was made up of longitudinal naturalistic speech output of three Yoruba-speaking children between 15and 36 months of age. We discovered the preponderance of null argument-NPs at the initial stage; subjects-NPs were easily omitted while object-NPs were hardly omitted; the three Yoruba-speaking children began to make use of overt argument-NPs from fifteen months and gradually, null argument-NPs gave way. We found no direct relationship between the acquisition of finiteness and the end of null arguments.Keywords: arguments, null, object, subject, finiteness, ellipses
水通道蛋白7对蛋白激酶B的影响%The Effect of Aquaglyceroporin 7 on Protein Kinase B Signaling Pathway
Institute of Scientific and Technical Information of China (English)
潘伟; 沈飞霞; 谷雪梅; 叶菁; 顾雪疆; 倪连松; 李卫平
2013-01-01
该文旨在探讨水通道蛋白7(AQP7)在3T3-L1脂肪细胞不同分化阶段的表达以及其对胰岛素信号通路中蛋白激酶B(PKB)的影响.通过培养3T3-L1前体脂肪细胞,诱导分化为成熟的脂肪细胞,用荧光定量PCR,Western blot、酶学方法分析显示,随3T3-L1脂肪细胞分化过程,AQP7与PKB磷酸化水平同步上升,同时培养基中释放的甘油浓度伴随AQP7的表达平行增加.以TNF-α处理分化成熟的脂肪细胞构建胰岛素抵抗模型,AQP7与PKB磷酸化水平均下降,转染高表达AQP7基因的重组腺病毒载体(Ad-AQP7)之后,随着AQP7表达上调,胰岛素刺激下的PKB磷酸化水平提高,并且葡萄糖代谢能力增强.由此可见,AQP7水平随3T3-L1脂肪细胞分化过程逐渐上升,其高表达可能通过增加PKB磷酸化水平改善胰岛素敏感性,提示AQP7可能成为治疗肥胖的一个重要作用靶点.%Aquaglyceroporin 7 (AQP7) is a water transporting protein which also regulates the glycerol efflux in adipocytes. The study of AQP7 might shed new light on the prevention and control of obesity. In this study, we aimed to analyze expression profiles of AQP7 in the different differentiation phase of adipocytes and the relationship between AQP7 and PKB in the insulin pathway. 3T3-L1 preadipocyte cells were induced fully differentiated. Insulin resistance in differentiated adipocytes was induced by TNF-α. Adenovirus overexpression AQP7 (Ad-AQP7) was constructed and transfected to adipocytes. The expression levels of AQP7 and phosphorylated PKB (p-PKB) were measured. The glycerol release from adipocytes and the change of glucose concentration in the culture medium were also tested.The AQP7 levels were gradually up-regulated along with the differentiation phase of 3T3-L1 preadipocytes, which was consistent with the expression levels of p-PKB. Overexpression of AQP7 by transfecting Ad-AQP7 to insulin resistant adipocytes could improve insulin sensitivity and glucose utilization, in
Energy dissipation in magnetic null points at kinetic scales
Olshevsky, Vyacheslav; Eriksson, Elin; Markidis, Stefano; Lapenta, Giovanni
2015-01-01
We use kinetic particle-in-cell and magnetohydrodynamic simulations supported by an observational dataset to investigate magnetic reconnection in clusters of null points in space plasma. The magnetic configuration under investigation is driven by fast adiabatic flux rope compression that dissipates almost half of the initial magnetic field energy. In this phase powerful currents are excited producing secondary instabilities, and the system is brought into a state of `intermittent turbulence' within a few ion gyro-periods. Reconnection events are distributed all over the simulation domain and energy dissipation is rather volume-filling. Numerous spiral null points interconnected via their spines form null lines embedded into magnetic flux ropes; null point pairs demonstrate the signatures of torsional spine reconnection. However, energy dissipation mainly happens in the shear layers formed by adjacent flux ropes with oppositely directed currents. In these regions radial null pairs are spontaneously emerging an...
Sidelobe Suppression with Null Steering by Independent Weight Control
Directory of Open Access Journals (Sweden)
Zafar-Ullah Khan
2015-01-01
Full Text Available A uniform linear array of n antenna elements can steer up to n-1 nulls. In situations where less than n-1 nulls are required to be steered, the existing algorithms have no criterion to utilize the remaining weights for sidelobe suppression. This work combines sidelobe suppression capability with null steering by independent weight control. For this purpose, the array factor is transformed as the product of two polynomials. One of the polynomials is used for null steering by independent weight control, while the second one is for sidelobe suppression whose coefficients or weights are determined by using convex optimization. Finally, a new structure is proposed to incorporate the product of two polynomials such that sidelobe suppression weights are decoupled from those of null steering weights. Simulation results validate the effectiveness of the proposed scheme.
Wormholes minimally violating the null energy condition
Energy Technology Data Exchange (ETDEWEB)
Bouhmadi-López, Mariam [Departamento de Física, Universidade da Beira Interior, 6200 Covilhã (Portugal); Lobo, Francisco S N; Martín-Moruno, Prado, E-mail: mariam.bouhmadi@ehu.es, E-mail: fslobo@fc.ul.pt, E-mail: pmmoruno@fc.ul.pt [Centro de Astronomia e Astrofísica da Universidade de Lisboa, Campo Grande, Edifício C8, 1749-016 Lisboa (Portugal)
2014-11-01
We consider novel wormhole solutions supported by a matter content that minimally violates the null energy condition. More specifically, we consider an equation of state in which the sum of the energy density and radial pressure is proportional to a constant with a value smaller than that of the inverse area characterising the system, i.e., the area of the wormhole mouth. This approach is motivated by a recently proposed cosmological event, denoted {sup t}he little sibling of the big rip{sup ,} where the Hubble rate and the scale factor blow up but the cosmic derivative of the Hubble rate does not [1]. By using the cut-and-paste approach, we match interior spherically symmetric wormhole solutions to an exterior Schwarzschild geometry, and analyse the stability of the thin-shell to linearized spherically symmetric perturbations around static solutions, by choosing suitable properties for the exotic material residing on the junction interface radius. Furthermore, we also consider an inhomogeneous generalization of the equation of state considered above and analyse the respective stability regions. In particular, we obtain a specific wormhole solution with an asymptotic behaviour corresponding to a global monopole.
The curious case of null warped space
Anninos, Dionysios; Compère, Geoffrey; de Buyl, Sophie; Detournay, Stéphane; Guica, Monica
2010-11-01
We initiate a comprehensive study of a set of solutions of topologically massive gravity known as null warped anti-de Sitter spacetimes. These are pp-wave extensions of three-dimensional anti-de Sitter space. We first perform a careful analysis of the linearized stability of black holes in these spacetimes. We find two qualitatively different types of solutions to the linearized equations of motion: the first set has an exponential time dependence, the second — a polynomial time dependence. The solutions polynomial in time induce severe pathologies and moreover survive at the non-linear level. In order to make sense of these geometries, it is thus crucial to impose appropriate boundary conditions. We argue that there exists a consistent set of boundary conditions that allows us to reject the above pathological modes from the physical spectrum. The asymptotic symmetry group associated to these boundary conditions consists of a centrally-extended Virasoro algebra. Using this central charge we can account for the entropy of the black holes via Cardy's formula. Finally, we note that the black hole spectrum is chiral and prove a Birkoff theorem showing that there are no other stationary axisymmetric black holes with the specified asymptotics. We extend most of the analysis to a larger family of pp-wave black holes which are related to Schrödinger spacetimes with critical exponent z.
The Curious Case of Null Warped Space
Anninos, Dionysios; de Buyl, Sophie; Detournay, Stéphane; Guica, Monica
2010-01-01
We initiate a comprehensive study of a set of solutions of topologically massive gravity known as null warped anti-de Sitter spacetimes. These are pp-wave extensions of three-dimensional anti-de Sitter space. We first perform a careful analysis of the linearized stability of black holes in these spacetimes. We find two qualitatively different types of solutions to the linearized equations of motion: the first set has an exponential time dependence, the second - a polynomial time dependence. The solutions polynomial in time induce severe pathologies and moreover survive at the non-linear level. In order to make sense of these geometries, it is thus crucial to impose appropriate boundary conditions. We argue that there exists a consistent set of boundary conditions that allows us to reject the above pathological modes from the physical spectrum. The asymptotic symmetry group associated to these boundary conditions consists of a centrally-extended Virasoro algebra. Using this central charge we can account for th...
Null weak singularities in plane-symmetric spacetimes
Ori, A
1998-01-01
We construct a new class of plane-symmetric solutions possessing a curvature singularity which is null and weak, like the spacetime singularity at the Cauchy horizon of spinning (or charged) black holes. We then analyse the stability of this singularity using a rigorous non-perturbative method. We find that within the framework of (linearly-polarized) plane-symmetric spacetimes this type of null weak singularity is locally stable. Generically, the singularity is also scalar-curvature. These observations support the new picture of the null weak singularity inside spinning (or charged) black holes, which is so far established primarily on the perturbative approach.
The Density of Coronal Null Points from Hinode and MDI
Longcope, Dana; DeForest, Craig
2009-01-01
Magnetic null points can be located numerically in a potential field extrapolation or their average density can be estimated from the Fourier spectrum of a magnetogram. We use both methods to compute the null point density from a quiet Sun magnetogram made with Hinode's NFI and from magnetograms from SOHO's MDI in both its high-resolution and low-resolution modes. All estimates of the super-chromospheric column density (z>1.5 Mm) agree with one another and with the previous measurements: 0.003 null points per square Mm of solar surface.
Molecular basis for the CAT-2 null phenotype in maize
International Nuclear Information System (INIS)
Previous reports have described several maize lines whose developmental patterns of catalase gene expression vary from the typical maize line, W64A. Among these variants are the lines A16 and A338, both found to be null for the CAT-2 protein. Identification of a third CAT-2 null line, designated A340, is described. RNA blots and S1 nuclease protection analysis, using [32P]-labeled dCTP, indicate that all three CAT-2 null lines produce a similarly shortened Cat2 transcript. The molecular basis for this aberrant Cat2 transcript is discussed
Performance Analysis of the Different Null Steering Techniques in the Field of Adaptive Beamforming
Fawad Zaman; Bilal Shoaib; Zafar Ullah Khan; Shahid Mehmood
2013-01-01
In this study, we compare the performance of three null steering techniques using uniform linear array. These techniques include Null Steering without using Phase Shifters, Null Steering by Decoupling the Real Weights and Null Steering by Decoupling the Complex Weights. The evaluation criteria of these techniques is based on the bases of different parameters i.e., null depth, main beam width, side lobe levels, number of steerable nulls, computational complexity and number of sensors used in t...
Waves and null congruences in a draining bathtub
Dempsey, David
2016-01-01
We study wave propagation in a draining bathtub: a fluid-mechanical black hole analogue in which perturbations are governed by a Klein-Gordon equation on an effective Lorentzian geometry. Like the Kerr spacetime, the draining bathtub geometry possesses an (effective) horizon, an ergosphere and null circular orbits. We propose that a `pulse' disturbance may be used to map out the light-cone of the effective geometry. First, we apply the eikonal approximation to elucidate the link between wavefronts, null geodesic congruences and the Raychaudhuri equation. Next, we solve the wave equation numerically in the time domain using the method of lines. Starting with Gaussian initial data, we demonstrate that a pulse will propagate along a null congruence and thus trace out the light-cone of the effective geometry. Our numerical results reveal features, such as wavefront intersections, frame-dragging, winding and interference effects, that are closely associated with the presence of null circular orbits and the ergosph...
A null-steering viewpoint of interferometric SAR
Energy Technology Data Exchange (ETDEWEB)
BICKEL,DOUGLAS L.
2000-05-02
Interferometric synthetic aperture radar (IFSAR) extends the two-dimensional imaging capability of traditional synthetic aperture radar to three-dimensions by using an aperture in the elevation plane to estimate the 3-D structure of the target. The operation of this additional aperture can be viewed from a null-steering point of view, rather than the traditional phase determination point of view. Knowing that IFSAR can be viewed from the null-steering perspective allows one to take advantage of the mathematical foundation developed for null-steering arrays. In addition, in some problems of interest in IFSAR the null-steering perspective provides better intuition and suggests alternative solutions. One example is the problem of estimating building height where layover is present.
Worldtube conservation laws for the null-timelike evolution problem
Winicour, Jeffrey
2011-01-01
I treat the worldtube constraints which arise in the null-timelike initial-boundary value problem for the Bondi-Sachs formulation of Einstein's equations. Boundary data on a worldtube and initial data on an outgoing null hypersurface determine the exterior spacetime by integration along the outgoing null geodsics. The worldtube constraints are a set of conservation laws which impose conditions on the integration constants. I show how these constraints lead to a well-posed initial value problem governing the extrinsic curvature of the worldtube, whose components are related to the integration constants. Possible applications to gravitational waveform extraction and to the well-posedness of the null-timelike initial-boundary value problem are discussed.
A Non-Null Annotation Inferencer for Java Bytecode
Hubert, Laurent
2008-01-01
We present a non-null annotations inferencer for the Java bytecode language. We previously proposed an analysis to infer non-null annotations and proved it soundness and completeness with respect to a state of the art type system. This paper proposes extensions to our former analysis in order to deal with the Java bytecode language. We have implemented both analyses and compared their behaviour on several benchmarks. The results show a substantial improvement in the precision and, despite bei...
Overt and Null Subject Pronouns in Jordanian Arabic
Directory of Open Access Journals (Sweden)
Islam M. Al-Momani
2015-08-01
Full Text Available The paper aims at examining the role that morphology plays in allowing and/or motivating sentences in Jordanian Arabic (hereafter JA to be formed with or without subject pronouns. It also aims at giving a comprehensive and descriptive presentation of the distribution of overt and null subject pronouns in JA, and tries to determine to what extent there is optionality in its system.Keywords: null subject pronouns, overt subjects, pro-drop languages, verbal inflectional morphology
On the failures of the null-hypothesis test
Longford, Nicholas
2015-01-01
This report comprises four reactions to the recent policy statement in Basic and Applied Social Psychology that announced a ban on null-hypothesis testing in that journal. A personal perspective is presented which agrees with the editors that null-hypothesis testing has become dysfunctional, but proposes a solution different from the editors'. In particular, application of formal statistical methods is defended, but they have to be tailored much more closely to the specifics of...
Another Nulling Hall-Effect Current-Measuring Circuit
Thibodeau, Phillip E.; Sullender, Craig C.
1993-01-01
Lightweight, low-power circuit provides noncontact measurement of alternating or direct current of many ampheres in main conductor. Advantages of circuit over other nulling Hall-effect current-measuring circuits is stability and accuracy increased by putting both analog-to-digital and digital-to-analog converters in nulling feedback loop. Converters and rest of circuit designed for operation at sampling rate of 100 kHz, but rate changed to alter time or frequency response of circuit.
Sequential weak continuity of null Lagrangians at the boundary
Czech Academy of Sciences Publication Activity Database
Kalamajska, A.; Kraemer, S.; Kružík, Martin
2014-01-01
Roč. 49, 3/4 (2014), s. 1263-1278. ISSN 0944-2669 R&D Projects: GA ČR GAP201/10/0357 Institutional support: RVO:67985556 Keywords : null Lagrangians * nonhomogeneous nonlinear mappings * sequential weak/in measure continuity Subject RIV: BA - General Math ematics Impact factor: 1.518, year: 2014 http://library.utia.cas.cz/separaty/2013/MTR/kruzik-sequential weak continuity of null lagrangians at the boundary.pdf
Designing asynchronous circuits using NULL convention logic (NCL)
Smith, Scott
2009-01-01
Designing Asynchronous Circuits using NULL Convention Logic (NCL) begins with an introduction to asynchronous (clockless) logic in general, and then focuses on delay-insensitive asynchronous logic design using the NCL paradigm. The book details design of input-complete and observable dual-rail and quad-rail combinational circuits, and then discusses implementation of sequential circuits, which require datapath feedback. Next, throughput optimization techniques are presented, including pipelining, embedding registration, early completion, and NULL cycle reduction. Subsequently, low-power design
Three-dimensional magnetic reconnection through a moving magnetic null
Directory of Open Access Journals (Sweden)
V. S. Lukin
2011-11-01
Full Text Available A computational study of three-dimensional magnetic reconnection between two flux ropes through a moving reconnection site is presented. The configuration is considered in the context of two interacting spheromaks constrained by a perfectly conducting cylindrical boundary and oriented to form a single magnetic field null at its center. The initial magnetic field configuration is embedded into a uniform thermal plasma and is unstable to tilting. As the spheromaks tilt, their magnetic fields begin to reconnect at the null, subsequently displacing both the null and the reconnection site. The motion of the reconnection region and the magnetic null are shown to be correlated, with stronger correlation and faster reconnection observed in plasmas with lower thermal to magnetic pressure ratio. It is also shown that ion inertial effects allow for yet faster reconnection, but do not qualitatively change the dynamics of the process. Implications of the coupling between moving magnetic nulls and reconnection sites, as well as of possible mechanisms for fast reconnection through a moving reconnection region, are discussed. The simulations are conducted using both single-fluid and Hall MHD plasma models within the HiFi multi-fluid modeling framework.
The causal topology of neutral 4-manifolds with null boundary
Georgiou, Nikos
2016-01-01
This paper considers aspects of 4-manifold topology from the point of view of a neutral metric, a point of view we call neutral causal topology. In particular, we construct and investigate neutral 4-manifolds with null boundary that arise from canonical 3- and 4-dimensional settings. A null hypersurface is foliated by its normal and, in the neutral case, inherits a pair of totally null planes at each point. This paper focuses on this structure in a number of classical settings The first construction is the conformal compactification of flat neutral 4-space into the 4-ball. The null foliation on the boundary in this case is the Hopf fibration on the 3-sphere and the totally null planes in the boundary are integrable. The metric on the 4-ball is a conformally flat, scalar-flat, positive Ricci curvature neutral metric. The second constructions are subsets of the 4-dimensional space of oriented geodesics in a 3-dimensional space-form, equipped with its canonical neutral metric. We consider all oriented geodesics ...
Resistivity at the field null of the FRC plasma
International Nuclear Information System (INIS)
In the absence of the major destructive instabilities, the configuration time is ultimately determined by particle and flux containment. If the profiles are ''gentle,'' then the anomalous flux-loss rate depends essentially on the anomalous resistivity at the field null. Conventional electrostatic quasi-linear models of anomalous cross-field resistive diffusivity are based upon the use of rvec E x rvec B drift velocities, and hence break down at the magnetic field null. In this paper, an electromagnetic treatment valid at the field null is developed, based upon the presence of flute-parity perturbations. An expression for anomalous resistivity at the field null in the quasi-linear approximation is derived by averaging in the ignorable direction over the random phases of the perturbations. The expression is valid for arbitrary (non-local) radial shapes of the perturbing modes (for example, the eigenfunctions need not be centered at the field null), and for an arbitrary ratio of real frequency to growth rate. The effective resistivity due to flute perturbations of the MHD type will be considered. 1 ref
Long-term Observations of Three Nulling Pulsars
Young, N J; Stappers, B W; Lyne, A G; Kramer, M
2015-01-01
We present an analysis of approximately 200 hours of observations of the pulsars J1634$-$5107, J1717$-$4054 and J1853$+$0505, taken over the course of 14.7 yr. We show that all of these objects exhibit long term nulls and radio-emitting phases (i.e. minutes to many hours), as well as considerable nulling fractions (NFs) in the range $\\sim67\\,\\% - 90\\,\\%$. PSR J1717$-$4054 is also found to exhibit short timescale nulls ($1 - 40~P$) and burst phases ($\\lesssim 200~P$) during its radio-emitting phases. This behaviour acts to modulate the NF, and therefore the detection rate of the source, over timescales of minutes. Furthermore, PSR J1853$+$0505 is shown to exhibit a weak emission state, in addition to its strong and null states, after sufficient pulse integration. This further indicates that nulls may often only represent transitions to weaker emission states which are below the sensitivity thresholds of particular observing systems. In addition, we detected a peak-to-peak variation of $33\\pm1\\,\\%$ in the spin-...
Pedestal and ELM characterisation of highly shaped single null and quasi double null plasmas in JET
Energy Technology Data Exchange (ETDEWEB)
Saibene, G.; Sartori, R.; Ingesson, L.C.; Loarte, A. [European Fusion Development Agreement Close Support Unit - Garching (Germany); Lomas, P.J.; Andrew, P.; Andrew, Y.; Guenther, K.; Korothov, A.; McDonald, D.; Meigs, A.G.; Parail, V.V.; Sharapov, S. [Euratom/Ukaea Association, Culham Science Centre, Abingdon, OX (United Kingdom); Becoulet, M.; Monier Garbet, P.; Rimini, F.G.; Thomas, P.R. [Association Euratom-CEA Cadarache, 13 - Saint-Paul-lez-Durance (France); Conway, G.D.; Stober, J. [Association Euratom-IPP, MPI fur Plasmophysik, Garching (Germany); Kempenaars, M. [Association Euratom-FOM, Rijnhuizen (Netherlands); Koslowski, H.R.; Perez, C.P. [Forschungszentrum Juelich GmbH, Inst. fuer Plasmaphysik, Euratom Association, Trilateral Euregio Cluster, Julich (Germany); Lonnroth, J.S.; Saarelma, S. [Association Euratom-Tekes, Helsinki Univ. of Techn., Hut (Finland); Nave, M.F. [Association Euratom/IST, Centro de Fusao Nuclear, Lisbon (Portugal); Ongena, J. [ECOLE ROYALE MILITAIRE (ERM-KMS), Lab. Plasma Physics, Bruxelles (Belgium)
2003-07-01
This paper presents the results of experiments carried out in JET to study the plasma pedestal and ELM (edge localized modes) behaviour of high density/high confinement ELMy H-modes, focusing on the exploration of the effects of the plasma boundary magnetic geometry (triangularity {delta}, as well as proximity to Double-Null (DN)) and of q{sub 95} on the pedestal parameters, edge stability and ELM losses. These experiments were aimed at the study of Type-I ELMs at high density and of the access to steady-state Type-II ELM regime for JET plasma conditions, comparing pedestal and ELM characteristics in high {delta} SN (single-null) and QDN (quasi double-null) plasmas, in similar experimental conditions. To date, complete Type-I ELM suppression has not been achieved in JET in steady state conditions, although at high shaping and density mixed phases of Type-I and Type-II ELMs are observed, both for SN and QDN plasmas. Long periods of Type II ELMs (up to 150 ms in QDN) are obtained at high n(pedestal), associated with an increase of magnetic and density fluctuations, compared to levels in pure Type-I ELMy H-modes. The location of these enhanced fluctuation region is likely to be near the pedestal top. Increasing q{sub 95} from {approx} 3 to {approx} 4.5 (by varying either Ip or Bt), does not facilitate the access to the Type-II ELM regime, in contrast to indications from other experiments. In general, at high q{sub 95}, the Type-I ELMs frequency is much higher than at q{sub 95} {approx} 3 (typical for JET ELMy H-modes), the plasma global confinement is reduced, the Type II activity weakens, with the Type I-III transition occurring at lower pedestal density than at lower q{sub 95}. The enhanced {approx} 20 kHz magnetic fluctuations with Type-II ELMs are identified with strong washboard modes, possible responsible for the increased inter-ELM transport. Power balance calculations do indeed show that the power carried by ELMs is reduced by more than a factor of two in the
The appearance, motion, and disappearance of three-dimensional magnetic null points
Murphy, Nicholas A; Haynes, Andrew L
2015-01-01
While theoretical models and simulations of magnetic reconnection often assume symmetry such that the magnetic null point when present is co-located with a flow stagnation point, the introduction of asymmetry typically leads to non-ideal flows across the null point. To understand this behavior, we present exact expressions for the motion of three-dimensional linear null points. The most general expression shows that linear null points move in the direction along which the vector field and its time derivative are antiparallel. Null point motion in resistive magnetohydrodynamics results from advection by the bulk plasma flow and resistive diffusion of the magnetic field, which allows non-ideal flows across topological boundaries. Null point motion is described intrinsically by parameters evaluated locally; however, global dynamics help set the local conditions at the null point. During a bifurcation of a degenerate null point into a null-null pair or the reverse, the instantaneous velocity of separation or conv...
Data volume and power of multiple tests with small sample size per null
Chi, Zhiyi
2008-01-01
In multiple hypothesis testing, the volume of data, defined as the number of replications per null times the total number of nulls, usually defines the amount of resource required. On the other hand, power is an important measure of performance for multiple testing. Due to practical constraints, the number of replications per null may not be large enough in terms of the difference between false and true nulls. For the case where the population fraction of false nulls is constant, we show that...
Stabilising a nulling interferometer using optical path difference dithering
Gabor, Pavel; Brachet, Frank; Ollivier, Marc; Decaudin, Michel; Jacquinod, Sophie; Labèque, Alain; Léger, Alain
2008-01-01
Context. Nulling interferometry has been suggested as the underlying principle for the Darwin and TPF-I exoplanet research missions. Aims. There are constraints both on the mean value of the nulling ratio, and on its stability. Instrument instability noise is most detrimental to the stability of the nulling performance. Methods. We applied a modified version of the classical dithering technique to the optical path difference in the scientific beam. Results. Using only this method, we repeatedly stabilised the dark fringe for several hours. This method alone sufficed to remove the 1/ f component of the noise in our setup for periods of 10 minutes, typically. These results indicate that performance stability may be maintained throughout the long-duration data acquisitions typical of exoplanet spectroscopy. Conclusions. We suggest that further study of possible stabilisation strategies should be an integral part of Darwin/TPF-I research and development
Null but not void: considerations for hypothesis testing.
Shaw, Pamela A; Proschan, Michael A
2013-01-30
Standard statistical theory teaches us that once the null and alternative hypotheses have been defined for a parameter, the choice of the statistical test is clear. Standard theory does not teach us how to choose the null or alternative hypothesis appropriate to the scientific question of interest. Neither does it tell us that in some cases, depending on which alternatives are realistic, we may want to define our null hypothesis differently. Problems in statistical practice are frequently not as pristinely summarized as the classic theory in our textbooks. In this article, we present examples in statistical hypothesis testing in which seemingly simple choices are in fact rich with nuance that, when given full consideration, make the choice of the right hypothesis test much less straightforward. Published 2012. This article is a US Government work and is in the public domain in the USA. PMID:22807023
Fully achromatic nulling interferometer (FANI) for high SNR exoplanet characterization
Henault, Francois
2015-01-01
Space-borne nulling interferometers have long been considered as the best option for searching and characterizing extra-solar planets located in the habitable zone of their parent stars. Solutions for achieving deep starlight extinction are now numerous and well demonstrated. However they essentially aim at realizing an achromatic central null in order to extinguish the star. In this communication is described a major improvement of the technique, where the achromatization process is extended to the entire fringe pattern. Therefore higher Signal-to-noise ratios (SNR) and appreciable simplification of the detection system should result. The basic principle of this Fully achromatic nulling interferometer (FANI) consists in inserting dispersive elements along the arms of the interferometer. Herein this principle is explained and illustrated by a preliminary optical system design. The typical achievable performance and limitations are discussed and some initial tolerance requirements are also provided
Optimization of myocardial nulling in pediatric cardiac MRI
Energy Technology Data Exchange (ETDEWEB)
Tham, Edythe B. [Stollery Children' s Hospital, University of Alberta, Department of Pediatrics, Division of Pediatric Cardiology, Edmonton, Alberta (Canada); Hung, Ryan W.; Crawley, Cinzia; Noga, Michelle L. [University of Alberta, Pediatric Radiology, Stollery Children' s Hospital, Edmonton (Canada); Myers, Kimberley A. [Alberta Children' s Hospital, Calgary (Canada)
2012-04-15
Current protocols to determine optimal nulling time in late enhancement imaging using adult techniques may not apply to children. To determine the optimal nulling time in anesthetised children, with the hypothesis that this occurs earlier than in adults. Sedated cardiac MRI was performed in 12 children (median age: 12 months, range: 1-60 months). After gadolinium administration, scout images at 2, 3, 4 and 10 min and phase sensitive inversion recovery (PSIR) images from 5 to 10 min were obtained. Signal-to-noise ratio (SNR) and inversion time (TI) were determined. Quality of nulling was assessed according to a grading score by three observers. Data was analysed using linear regression, Kruskal-Wallis and quadratic-weighted kappa statistics. One child with a cardiomyopathy had late enhancement. Good agreement in nulling occurred for scout images at 2 ({kappa} = 0.69) and 3 ({kappa} = 0.66) min and moderate agreement at 4 min ({kappa} = 0.57). Agreement of PSIR images was moderate at 7 min ({kappa} = 0.44) and poor-fair at other times. There were significant correlations between TI and scout time (r = 0.61, P < 0.0001), and SNR and kappa (r = 0.22, P = 0.017). Scout images at 2-4 min can be used to determine the TI with little variability. Image quality for PSIR images was highest at 7 min and SNR optimal at 7-9 min. TI increases with time and should be adjusted frequently during imaging. Thus, nulling times in children differ from nulling times in adults when using standard adult techniques. (orig.)
Magnetoacoustic Waves in Stratified Atmospheres with a Magnetic Null Point
Tarr, Lucas A.; Linton, Mark; Leake, James E.
2016-05-01
Magnetic fields strongly modify the propagation of MHD waves from the photosphere to the low corona, as can be shown exactly for the most simple case of a uniform magnetic field and isothermally stratrified atmosphere. For slightly more realistic scenarios, where both the atmospheric parameters and the magnetic field vary spatially, the linear MHD equations typically cannot be solved analytically. We use the Lagrangian Remap code--a nonlinear, shock-capturing MHD code--to study the propagation of initially acoustic wavepackets through a model 2D atmosphere that includes a gravitationally stratified chromosphere, transition region, and low corona. The magnetic field is formed by three photospheric concentrations and includes a single magnetic null point, resulting in an inhomogeneous system with a magnetic dome topology. A portion of an introduced wavepacket will refract toward the null due to the varying Alfven speed. Waves incident on the equipartition contour surrounding the null, where the sound and Alfven speeds coincide, partially transmit, reflect, and mode convert between branches of the local dispersion relation. Outward propagating slow modes generated during conversion become strongly concentrated along the set of field lines passing near the null. Acoustic energy is beamed back downwards towards each photospheric foot point, and upwards along one separatrix that exits the top of the numerical domain. Changes in the dominant restoring force for the wavepacket, between the Lorentz and pressure gradient forces, lead to a buildup of current density along topologically important features of the system (the null point and its four separatrices) and can drive reconnection at the null point itself. Ohmic dissipation of the currents locally heats the plasma. We find that the amount of current accumulation depends on where the centroid of a wavepacket initial crosses the photosphere, but does not simply coincide with regions of open versus closed magnetic field or
A Matrix Model for the Null-Brane
Robbins, Daniel; Sethi, Savdeep
2005-01-01
The null-brane background is a simple smooth 1/2 BPS solution of string theory. By tuning a parameter, this background develops a big crunch/big bang type singularity. We construct the DLCQ description of this space-time in terms of a Yang-Mills theory on a time-dependent space-time. Our dual Matrix description provides a non-perturbative framework in which the fate of both (null) time, and the string S-matrix can be studied.
Effect of residual phase gradients in optical null interference.
Naik, Dinesh N; Pradeep Chakravarthy, T; Viswanathan, Nirmal K
2016-01-01
A scheme to study the effect of residual phase gradients in an optical interference between two out-of-phase Gaussian beams is proposed. In a Sagnac interferometer configured to provide a null output, a variable linear phase swept across the null point unfolds an optical field rotation due to an apparently negligible residual phase gradient present orthogonal to the linear phase sweep. As the optical beam that rotates around its propagation axis carries orbital angular momentum, the experimental results presented in this Letter could provide an insight into the momentum change associated with the energy redistribution in the fundamental phenomenon of optical interference. PMID:26696166
Quantization in Spacetime from Null Paths in Higher Dimensions
Wesson, Paul S.
2008-01-01
Massive particles on timelike paths in spacetime can be viewed as moving on null paths in a higher-dimensional manifold. This and other consequences follow from the use of Campbell's theorem to embed 4D general relativity in non-compactified 5D Kaluza-Klein theory. We now show that it is possible in principle to obtain the standard rule for quantization in 4D from the canonical metric with null paths in 5D. Particle mass can be wavelike, as suggested originally by Dirac, and other 4D/5D conse...
A Matrix Model for the Null-Brane
Robbins, D; Robbins, Daniel; Sethi, Savdeep
2006-01-01
The null-brane background is a simple smooth 1/2 BPS solution of string theory. By tuning a parameter, this background develops a big crunch/big bang type singularity. We construct the DLCQ description of this space-time in terms of a Yang-Mills theory on a time-dependent space-time. Our dual Matrix description provides a non-perturbative framework in which the fate of both (null) time, and the string S-matrix can be studied.
A matrix model for the null-brane
International Nuclear Information System (INIS)
The null-brane background is a simple smooth 1/2 BPS solution of string theory. By tuning a parameter, this background develops a big crunch/big bang type singularity. We construct the DLCQ description of this space-time in terms of a Yang-Mills theory on a time-dependent space-time. Our dual Matrix description provides a non-perturbative framework in which the fate of both (null) time, and the string S-matrix can be studied
Null geodesics in a magnetically charged stringy black hole spacetime
Kuniyal, Ravi Shankar; Uniyal, Rashmi; Nandan, Hemwati; Purohit, K. D.
2016-04-01
We study the null geodesics of a four-dimensional magnetic charged black hole spacetime arising in string theory. The behaviour of effective potential in view of the different values of black hole parameters are analysed in the equatorial plane. The possible orbits for null geodesics are also discussed in view of the different values of the impact parameter. We have also calculated the frequency shift of photons in this spacetime. The results are compared to those obtained for the electrically charged stringy black hole spacetime and the Schwarzschild black hole spacetime in general relativity.
Quantization in Spacetime from Null Paths in Higher Dimensions
Wesson, Paul S
2008-01-01
Massive particles in spacetime can be viewed as moving on null paths in a higher-dimensional manifold. Using a novel gauge, we show that geometric structure in 5D can lead to the standard rule for quantization in 4D. Particle mass can be wavelike, as suggested originally by Dirac, and other 5D/4D consequences are outlined.
Progress in broadband infrared nulling technology for TPF
Wallace, J. Kent; Brown, Ken; Bartos, Randall; Gappinger, Robert; Loya, Frank; Macdonald, Dan; Moser, Steve; Negron, John
2005-01-01
TPF-I has set for itself a host of challenging technical milestones along its path to demonstrating the feasibility of infrared nulling for planet detection Progress in each of these areas of technical development will be reviewed as well as progress in meeting the overarching technical milestones.
Circumpulsar Asteroids: Inferences from Nulling Statistics and High Energy Correlations
Shannon, Ryan; Cordes, J. M.
2006-12-01
We have proposed that some classes of radio pulsar variability are associated with the entry of neutral asteroidal material into the pulsar magnetosphere. The region surrounding neutron stars is polluted with supernova fall-back material, which collapses and condenses into an asteroid-bearing disk that is stable for millions of years. Over time, collisional and radiative processes cause the asteroids to migrate inward until they are heated to the point of ionization. For older and cooler pulsars, asteroids ionize within the large magnetospheres and inject a sufficient amount of charged particles to alter the electrodynamics of the gap regions and modulate emission processes. This extrinsic model unifies many observed phenomena of variability that occur on time scales that are disparate with the much shorter time scales associated with pulsars and their magnetospheres. One such type of variability is nulling, in which certain pulsars exhibit episodes of quiescence that for some objects may be as short as a few pulse periods, but, for others, is longer than days. Here, in the context of this model, we examine the nulling phenomenon. We analyze the relationship between in-falling material and the statistics of nulling. In addition, as motivation for further high energy observations, we consider the relationship between the nulling and other magnetospheric processes.
The appearance, motion, and disappearance of three-dimensional magnetic null points
Energy Technology Data Exchange (ETDEWEB)
Murphy, Nicholas A., E-mail: namurphy@cfa.harvard.edu [Harvard-Smithsonian Center for Astrophysics, Cambridge, Massachusetts 02138 (United States); Parnell, Clare E.; Haynes, Andrew L. [School of Mathematics and Statistics, University of St Andrews, North Haugh, St Andrews, Fife KY16 9SS (United Kingdom)
2015-10-15
While theoretical models and simulations of magnetic reconnection often assume symmetry such that the magnetic null point when present is co-located with a flow stagnation point, the introduction of asymmetry typically leads to non-ideal flows across the null point. To understand this behavior, we present exact expressions for the motion of three-dimensional linear null points. The most general expression shows that linear null points move in the direction along which the magnetic field and its time derivative are antiparallel. Null point motion in resistive magnetohydrodynamics results from advection by the bulk plasma flow and resistive diffusion of the magnetic field, which allows non-ideal flows across topological boundaries. Null point motion is described intrinsically by parameters evaluated locally; however, global dynamics help set the local conditions at the null point. During a bifurcation of a degenerate null point into a null-null pair or the reverse, the instantaneous velocity of separation or convergence of the null-null pair will typically be infinite along the null space of the Jacobian matrix of the magnetic field, but with finite components in the directions orthogonal to the null space. Not all bifurcating null-null pairs are connected by a separator. Furthermore, except under special circumstances, there will not exist a straight line separator connecting a bifurcating null-null pair. The motion of separators cannot be described using solely local parameters because the identification of a particular field line as a separator may change as a result of non-ideal behavior elsewhere along the field line.
Performance Analysis of the Different Null Steering Techniques in the Field of Adaptive Beamforming
Directory of Open Access Journals (Sweden)
Fawad Zaman
2013-04-01
Full Text Available In this study, we compare the performance of three null steering techniques using uniform linear array. These techniques include Null Steering without using Phase Shifters, Null Steering by Decoupling the Real Weights and Null Steering by Decoupling the Complex Weights. The evaluation criteria of these techniques is based on the bases of different parameters i.e., null depth, main beam width, side lobe levels, number of steerable nulls, computational complexity and number of sensors used in the array. The validity and effectiveness of these techniques is reflected by the resultant radiation pattern of the array.
Proof of a Null Penrose Conjecture using a new Quasi-local Mass
Roesch, Henri
2016-01-01
We define an explicit quasi-local mass functional which is non-decreasing along all foliations (satisfying a convexity assumption) of null cones. We use this new functional to prove the null Penrose conjecture under fairly generic conditions.
Conserved quantities at spatial and null infinity: The Penrose potential
International Nuclear Information System (INIS)
We define a superpotential for energy-momentum and rotation momentum which is built out of the conformal tensor and a bivector. This superpotential is identified with that used by Penrose in his definition of quasilocal energy. It is applied to the definition of energy-momentum and rotation momentum at spatial and at null infinities. At spatial infinity the results are in agreement with those of Ashtekar and Hansen. At null infinity the results are unsatisfactory; they are tied to a specific Bondi frame. Thus, they are not in agreement with the results of Tamburino and Winicour, Geroch and Winicour, nor with those of Dray and Streubel. Some reasons for this failure are discussed
Null Cones and Einstein's Equations in Minkowski Spacetime
Pitts, J B
2004-01-01
If Einstein's equations are to describe a field theory of gravity in Minkowski spacetime, then causality requires that the effective curved metric must respect the flat background metric's null cone. The kinematical problem is solved using a generalized eigenvector formalism based on the Segr\\'{e} classification of symmetric rank 2 tensors with respect to a Lorentzian metric. Securing the correct relationship between the two null cones dynamically plausibly is achieved using the naive gauge freedom. New variables tied to the generalized eigenvector formalism reduce the configuration space to the causality-respecting part. In this smaller space, gauge transformations do not form a group, but only a groupoid. The flat metric removes the difficulty of defining equal-time commutation relations in quantum gravity and guarantees global hyperbolicity.
Null warped AdS in higher spin gravity
Breunhoelder, Veronika; Grumiller, Daniel; Prohazka, Stefan
2015-01-01
We equip three-dimensional spin-3 gravity in the principal embedding with a new set of boundary conditions that we call "asymptotically null warped AdS". We find a chiral copy of the Polyakov-Bershadsky algebra as asymptotic symmetry algebra, reminiscent of the situation in topologically massive gravity with strict null warped AdS boundary conditions. We prove the invertibility of the map between zuvielbein and metric variables and construct a global gauge transformation to half of AdS spin-3 gravity in the diagonal embedding. This explains why the theory is chiral and why the Polyakov-Bershadsky algebra arises. We then introduce chemical potentials, derive the entropy, free energy, and the holographic response functions, and conclude with a discussion.
Nonparametric Regression Estimation for Multivariate Null Recurrent Processes
Directory of Open Access Journals (Sweden)
Biqing Cai
2015-04-01
Full Text Available This paper discusses nonparametric kernel regression with the regressor being a \\(d\\-dimensional \\(\\beta\\-null recurrent process in presence of conditional heteroscedasticity. We show that the mean function estimator is consistent with convergence rate \\(\\sqrt{n(Th^{d}}\\, where \\(n(T\\ is the number of regenerations for a \\(\\beta\\-null recurrent process and the limiting distribution (with proper normalization is normal. Furthermore, we show that the two-step estimator for the volatility function is consistent. The finite sample performance of the estimate is quite reasonable when the leave-one-out cross validation method is used for bandwidth selection. We apply the proposed method to study the relationship of Federal funds rate with 3-month and 5-year T-bill rates and discover the existence of nonlinearity of the relationship. Furthermore, the in-sample and out-of-sample performance of the nonparametric model is far better than the linear model.
MHD Mode Conversion around a 2D Magnetic Null Point
McDougall, A M D; 10.1063/1.3099224
2009-01-01
Mode conversion occurs when a wave passes through a region where the sound and Alfven speeds are equal. At this point there is a resonance, which allows some of the incident wave to be converted into a different mode. We study this phenomenon in the vicinity of a two-dimensional, coronal null point. As a wave approaches the null it passes from low- to high-beta plasma, allowing conversion to take place. We simulate this numerically by sending in a slow magnetoacoustic wave from the upper boundary; as this passes through the conversion layer a fast wave can clearly be seen propagating ahead. Numerical simulations combined with an analytical WKB investigation allow us to determine and track both the incident and converted waves throughout the domain.
Analysis of nulling phase functions suitable to image plane coronagraphy
Henault, Francois; Verinaud, Christophe
2016-01-01
Coronagraphy is a very efficient technique for identifying and characterizing extra-solar planets orbiting in the habitable zone of their parent star, especially when used in a space environment. An important family of coronagraphs is based on phase plates located at an intermediate image plane of the optical system, that spread the starlight outside the "Lyot" exit pupil plane of the instrument. In this communication we present a set of candidate phase functions generating a central null at the Lyot plane, and study how it propagates to the image plane of the coronagraph. These functions include linear azimuthal phase ramps (the well-known optical vortex), azimuthally cosine-modulated phase profiles, and circular phase gratings. Numerical simulations of the expected null depth, inner working angle, sensitivity to pointing errors, effect of central obscuration located at the pupil or image planes, and effective throughput including image mask and Lyot stop transmissions are presented and discussed. The prelim...
Holographic proof of the quantum null energy condition
Koeller, Jason; Leichenauer, Stefan
2016-07-01
We use holography to prove the quantum null energy condition (QNEC) at leading order in large N for CFTs and relevant deformations of CFTs in Minkowski space which have Einstein gravity duals. Given any codimension-two surface Σ which is locally stationary under a null deformation in the direction k at the point p , the QNEC is a lower bound on the energy-momentum tensor at p in terms of the second variation of the entropy to one side of Σ : ⟨Tk k⟩≥S''/2 π √{h } . In a CFT, conformal transformations of this inequality give results which apply when Σ is not locally stationary. The QNEC was proven previously for free theories, and taken together with our result this provides strong evidence that the QNEC is a true statement about quantum field theory in general.
Quantization of black hole entropy from unstable circular null geodesics
Wei, Shao-Wen; Liu, Yu-Xiao; Fu, Chun-E.
2016-04-01
The quasinormal mode frequencies can be understood from the massless particles trapped at the unstable circular null geodesics and slowly leaking out to infinity. Based on this viewpoint, in this paper, we semiclassically construct the entropy spectrum of the static and stationary black holes from the null geodesics. The result shows that the spacing of the entropy spectrum only depends on the property of the black hole in the eikonal limit. Moreover, for a black hole far from the extremal case, the spacing is found to be smaller than 2πħ for any dimension, which is very different from the result of the previous work by using the usual quasinormal mode frequencies.
Magnetic Reconnection at a Three-dimensional Solar Null Point
DEFF Research Database (Denmark)
Frederiksen, Jacob Trier; Baumann, Gisela; Galsgaard, Klaus;
2012-01-01
Using a specific solar null point reconnection case studied by Masson et al (2009; ApJ 700, 559) we investigate the dependence of the reconnection rate on boundary driving speed, numerical resolution, type of resistivity (constant or numerical), and assumed stratification (constant density or solar......-like). The MHD simulations start out from a potential magnetic field containing a null-point, obtained from a SOHO magnetogram extrapolation approximately 8 hours before a C-class flare was observed. The magnetic field is stressed with a boundary motion pattern similar to the horizontal motions observed by SOHO...... during the period preceding the flare. The general behavior is nearly independent of driving speed and numerical resolution, and is also very similar in stratified and unstratified models, provided only that the boundary motions are slow enough....
Hanot, Charles
2010-01-01
A unique statistical data analysis method has been developed for reducing nulling interferometry data. The idea is to make use of the statistical distributions of the fluctuating null depths and beam intensities to retrieve the astrophysical null depth in the presence of fluctuations. The approach yields an accuracy much better than is possible with standard data reduction methods, because the accuracy of the null depth is not limited by the sizes of the phase and intensity errors but by the ...
Oscillatory null singularity inside realistic spinning black holes
Ori, Amos
2001-01-01
We calculate the asymptotic behavior of the curvature scalar $(Riemann)^2$ near the null weak singularity at the inner horizon of a generic spinning black hole, and show that this scalar oscillates infinite number of times while diverging. The dominant parallelly-propagated Riemann components oscillate in a similar manner. This oscillatory behavior, which is in a remarkable contrast to the monotonic mass-inflation singularity in spherical charged black holes, is caused by the dragging of iner...
The Tolman VII solution, trapped null orbits and w - modes
Neary, N J; Lake, K; Neary, Nicholas; Ishak, Mustapha; Lake, Kayll
2001-01-01
The Tolman VII solution is an exact static spherically symmetric perfect fluid solution of Einstein's equations that exhibits a surprisingly good approximation to a neutron star. We show that this solution exhibits trapped null orbits in a causal region even for a tenuity (total radius to mass ratio) $> 3$. In this region the dynamical part of the potential for axial w - modes dominates over the centrifugal part.
Do electromagnetic waves always propagate along null geodesics?
Asenjo, Felipe A
2016-01-01
We find exact solutions to Maxwell equations written in terms of four-vector potentials in non--rotating, as well as in G\\"odel and Kerr spacetimes. Exact electromagnetic waves solutions are written on given gravitational field backgrounds where they evolve. We find that in non--rotating spherical symmetric spacetimes, electromagnetic plane waves travel along null geodesics. However, electromagnetic plane waves on G\\"odel and Kerr spacetimes do not exhibit that behavior.
Partial Rescue of the Amelogenin Null Dental Enamel Phenotype*
LI, YONG; Suggs, Cynthia; Wright, J. Timothy; Yuan, Zhi-An; Aragon, Melissa; Fong, Hanson; Simmons, Darrin; Daly, Bill; Golub, Ellis E.; Harrison, Gerald; Kulkarni, Ashok B.; Gibson, Carolyn W.
2008-01-01
The amelogenins are the most abundant secreted proteins in developing dental enamel. Enamel from amelogenin (Amelx) null mice is hypoplastic and disorganized, similar to that observed in X-linked forms of the human enamel defect amelogenesis imperfecta resulting from amelogenin gene mutations. Both transgenic strains that express the most abundant amelogenin (TgM180) have relatively normal enamel, but strains of mice that express a mutated amelogenin (TgP70T), which leads to amelogenesis impe...
Nulling Hall-Effect Current-Measuring Circuit
Sullender, Craig C.; Vazquez, Juan M.; Berru, Robert I.
1993-01-01
Circuit measures electrical current via combination of Hall-effect-sensing and magnetic-field-nulling techniques. Known current generated by feedback circuit adjusted until it causes cancellation or near cancellation of magnetic field produced in toroidal ferrite core by current measured. Remaining magnetic field measured by Hall-effect sensor. Circuit puts out analog signal and digital signal proportional to current measured. Accuracy of measurement does not depend on linearity of sensing components.
Null distribution of multiple correlation coefficient under mixture normal model
Hydar Ali; Nagar, Daya K.
2002-01-01
The multiple correlation coefficient is used in a large variety of statistical tests and regression problems. In this article, we derive the null distribution of the square of the sample multiple correlation coefficient, R2, when a sample is drawn from a mixture of two multivariate Gaussian populations. The moments of 1−R2 and inverse Mellin transform have been used to derive the density of R2.
Atoms of weakly null-additive monotone measures and integrals
Czech Academy of Sciences Publication Activity Database
Li, J.; Mesiar, Radko; Pap, E.
2014-01-01
Roč. 257, č. 1 (2014), s. 183-192. ISSN 0020-0255 R&D Projects: GA ČR GAP402/11/0378 Institutional support: RVO:67985556 Keywords : atom of a measure * weak null-additivty * monotone measure Subject RIV: BA - General Mathematics Impact factor: 4.038, year: 2014 http://library.utia.cas.cz/separaty/2014/E/mesiar-0432227.pdf
A null model for testing thermodynamic optimization in ecological systems
Doyle, Santiago R.; Carusela, Florencia; Guala, Sebastián; Momo, Fernando
2011-01-01
Several authors have hypothesized that ecological systems are subject to thermodynamic optimization, which, if proven correct, could represent a long sought general principle of organization in ecology. Although there have been recent advances, this still remains as an unresolved topic, and ecologists lack a general method to test thermodynamic optimization hypotheses in specific systems. Here we present a general, novel approach that allows generating a null model for testing thermodynamic o...
A semilinear hyperbolic system violating the null condition
Katayama, Soichiro; Sunagawa, Hideaki
2012-01-01
We consider a two-component system of semilinear wave equations in three space dimensions with quadratic nonlinear terms not satisfying the null condition. We prove small data global existence of the classical solution if some quantity defined from the nonlinearities is positive. It is also shown that only one component is dissipated and the other one behaves like a (non-trivial) free solution in the large time.
Zero emission city. Preliminary study; Null-Emissions-Stadt. Sondierungsstudie
Energy Technology Data Exchange (ETDEWEB)
Diefenbach, N.; Enseling, A.; Werner, P.; Flade, A.; Greiff, R.; Hennings, D.; Muehlich, E.; Wullkopf, U.; Sturm, P.; Kieslich, W.; Born, R.; Grossklos, M.; Hatteh, R.; Mueller, K.; Ratschow, A.; Valouch-Fornoff, C.
2002-10-01
The idea of a 'zero emission city' is investigated by the Institut Wohnen und Umwelt on behalf of the Federal Minister of Education and Research. After describing the current situation and defining the key parameters of a 'zero emission city', settlement structures, power supply, production processes and transportation are analyzed and linked with the communal action level to obtain a framework for research, activities and actions. The study ends with recommendations for a research programme 'zero emission city'. (orig.) [German] Die von den Staedten der Industrielaender ausgehenden Emissionen stellen im Hinblick auf die globalen Belastungen wie z.B. Treibhauseffekt, Ozonabbau und Versauerung das Hauptproblem dar. Aus diesem Grunde bietet es sich an, den Gedanken der 'Null-Emissions-Stadt', der Vision einer moeglichst emissionsfreien Stadt, aufzugreifen und auf seine Tragfaehigkeit fuer innovative Handlungsmodelle forschungsstrategisch zu ueberpruefen. Das Bundesministerium fuer Bildung und Forschung hat das Institut Wohnen und Umwelt beauftragt, in einer Sondierungsstudie dieser Fragestellung nachzugehen. Nach der Festlegung der Ausgangsbedingungen und Eckpunkte der Vision 'Null-Emissions-Stadt' und der Analyse der vier Handlungsfelder Siedlungsstrukturen, Energieversorgung, Produktionsprozesse (Kreislaufwirtschaft) und Verkehr werden diese aufgegriffen und mit der kommunalen Handlungsebene verknuepft und zu einem Forschungs-, Handlungs- und moeglichen Aktionsrahmen zusammengefuegt. Die Studie schliesst mit Hinweisen fuer die Gestaltung eines Forschungsprogramms 'Null-Emissions-Stadt'. (orig.)
Variational principle for gravity with null and non-null boundaries: a unified boundary counter-term
Energy Technology Data Exchange (ETDEWEB)
Parattu, Krishnamohan; Chakraborty, Sumanta; Padmanabhan, T. [IUCAA, Post Bag 4, Pune (India)
2016-03-15
It is common knowledge that the Einstein-Hilbert action does not furnish a well-posed variational principle. The usual solution to this problem is to add an extra boundary term to the action, called a counter-term, so that the variational principle becomes well-posed. When the boundary is spacelike or timelike, the Gibbons-Hawking-York counter-term is the most widely used. For null boundaries, we had proposed a counter-term in a previous paper. In this paper, we extend the previous analysis and propose a counter-term that can be used to eliminate variations of the ''off-the-surface'' derivatives of the metric on any boundary, regardless of its spacelike, timelike or null nature. (orig.)
Variational Principle for Gravity with Null and Non-null boundaries: A Unified Boundary Counter-term
Parattu, Krishnamohan; Padmanabhan, T
2016-01-01
It is common knowledge that the Einstein-Hilbert action does not furnish a well-posed variational principle. The usual solution to this problem is to add an extra boundary term to the action, called a counter-term, so that the variational principle becomes well-posed. When the boundary is spacelike or timelike, the Gibbons-Hawking-York counter-term is the most widely used. For null boundaries, we had proposed a counter-term in a previous paper. In this paper, we extend the previous analysis and propose a counter-term that can be used to eliminate variations of the "off-the-surface" derivatives of the metric on any boundary, regardless of its spacelike, timelike or null nature.
Null controllable region of delta operator systems subject to actuator saturation
Yang, Hongjiu; Yan, Ce; Xia, Yuanqing; Zhang, Jinhui
2016-07-01
In this paper, we give exact description of null controllable regions for delta operator systems subject to actuator saturation. The null controllable region is in terms of a set of extremal trajectories of anti-stable subsystems. For the delta operator system with real eigenvalues or complex eigenvalues, the description is simplified to an explicit formula which is used to characterise the boundary of a null controllable region. The relations of null controllable regions are shown separately for continuous-time systems, discrete-time systems and delta operator systems. Two numerical examples are given to illustrate the effectiveness of the proposed techniques on null controllable regions.
Broadband Achromatic Phase Shifter for a Nulling Interferometer
Bolcar, Matthew R.; Lyon, Richard G.
2011-01-01
Nulling interferometry is a technique for imaging exoplanets in which light from the parent star is suppressed using destructive interference. Light from the star is divided into two beams and a phase shift of radians is introduced into one of the beams. When the beams are recombined, they destructively interfere to produce a deep null. For monochromatic light, this is implemented by introducing an optical path difference (OPD) between the two beams equal to lambda/2, where lambda is the wavelength of the light. For broadband light, however, a different phase shift will be introduced at each wavelength and the two beams will not effectively null when recombined. Various techniques have been devised to introduce an achromatic phase shift a phase shift that is uniform across a particular bandwidth. One popular technique is to use a series of dispersive elements to introduce a wavelength-dependent optical path in one or both of the arms of the interferometer. By intelligently choosing the number, material and thickness of a series of glass plates, a nearly uniform, arbitrary phase shift can be introduced between two arms of an interferometer. There are several constraints that make choosing the number, type, and thickness of materials a difficult problem, such as the size of the bandwidth to be nulled. Several solutions have been found for bandwidths on the order of 20 to 30 percent (Delta(lambda)/lambda(sub c)) in the mid-infrared region. However, uniform phase shifts over a larger bandwidth in the visible regime between 480 to 960 nm (67 percent) remain difficult to obtain at the tolerances necessary for exoplanet detection. A configuration of 10 dispersive glass plates was developed to be used as an achromatic phase shifter in nulling interferometry. Five glass plates were placed in each arm of the interferometer and an additional vacuum distance was also included in the second arm of the interferometer. This configuration creates a phase shift of pi radians with
A Visualization of Null Geodesics for the Bonnor Massive Dipole
Oliva-Mercado, Guillermo Andree; Cordero-García, Iván; Frutos-Alfaro, Francisco
2015-01-01
In this work we simulate null geodesics for the Bonnor massive dipole metric by implementing a symbolic-numerical algorithm in Sage and Python. This program is also capable of visualizing in 3D, in principle, the geodesics for any given metric. Geodesics are launched from a common point, collectively forming a cone of light beams, simulating a solid-angle section of a point source in front of a massive object with a magnetic field. Parallel light beams also were considered, and their bending due to the curvature of the space-time was simulated.
Trapping of waves and null geodesics for rotating black holes
Dyatlov, Semyon; Zworski, Maciej
2013-01-01
We present dynamical properties of linear waves and null geodesics valid for Kerr and Kerr-de Sitter black holes and their stationary perturbations. The two are intimately linked by the geometric optics approximation. For the nullgeodesic flow the key property is the r-normal hyperbolicity of the trapped set and for linear waves it is the distribution of quasi-normal modes: the exact quantization conditions do not hold for perturbations but the bounds on decay rates and the statistics of freq...
Why is the null HBT result at RHIC so interesting?
Gyulassy, M
2003-01-01
Pion interferometry (HBT of A+A) data have posed a thorn in the theoretical interpretation of AA collisions at RHIC (sq root s = 130 AGeV). How can R sub o sub u sub t approx R sub s sub i sub d sub e approx R sub l sub o sub n sub g and remain so between AGS and RHIC? Where is the QGP Stall? Can elephants hide along the x sub 0 sup + dimension? We rummage old hydrodynamic scenarios and uncover some previously ignored NULL solutions. (author)
Null controllability in a fluid-solid structure model
Raymond, J.-P.; Vanninathan, M.
We consider a system coupling the Stokes equations in a two-dimensional domain with a structure equation which is a system of ordinary differential equations corresponding to a finite dimensional approximation of equations modeling deformations of an elastic body or vibrations of a rigid body. For that system we establish a null controllability result for localized distributed controls acting only in the fluid equations and there is no control in the solid part. This controllability result follows from a Carleman inequality that we prove for the adjoint system.
Scale anomalies imply violation of the averaged null energy condition
Visser, M
1994-01-01
Considerable interest has recently been expressed regarding the issue of whether or not quantum field theory on a fixed but curved background spacetime satisfies the averaged null energy condition (ANEC). A comment by Wald and Yurtsever [Phys. Rev. D43, 403 (1991)] indicates that in general the answer is no. In this note I explore this issue in more detail, and succeed in characterizing a broad class of spacetimes in which the ANEC is guaranteed to be violated. Finally, I add some comments regarding ANEC violation in Schwarzschild spacetime.
Conformal symmetry wormholes and the null energy condition
Kuhfittig, Peter K F
2016-01-01
In this paper we seek a relationship between the assumption of conformal symmetry and the exotic matter needed to hold a wormhole open. By starting with a Morris-Thorne wormhole having a constant energy density, it is shown that the conformal factor provides the extra degree of freedom sufficient to account for the exotic matter. The same holds for Morris-Thorne wormholes in a noncommutative-geometry setting. Applied to thin shells, there would exist a radius that results in a wormhole with positive surface density and negative surface pressure and which violates the null energy condition on the thin shell.
Five-dimensional null & time-like supersymmetric geometries
Pasini, Giulio
2015-01-01
We show that there exist supersymmetric solutions of five-dimensional, pure, $\\mathcal{N}=1$ Supergravity whose supersymmetric Killing vector, built out of the Killing spinor, is null on an open set of the underlying space-time manifold and generically time-like on the complementary set. We explicitly construct such solutions by using a multi-center Gibbons-Hawking base. Although many of these solutions have infinite charges, we find explicit examples with finite charges that asymptote to $AdS_3\\times S_2$ and discuss their physical interpretation.
Null weak values in multi-level systems
Zilberberg, Oded; Romito, Alessandro; Gefen, Yuval
2013-01-01
A two-step measurement protocol of a quantum system, known as weak value (WV), has been introduced more than two decades ago by Aharonov et al. [1], and has since been studied in various contexts. Here we discuss another two-step measurement protocol which we dub null weak value (NWV). The protocol consists of a partial-collapse measurement followed by quantum manipulation on the system and finally a strong measurement. The first step is a strong measurement which takes place with small proba...
Holographic Description of Negative Null Energy in Squeezed Vacuum States
Lee, Da-Shin
2016-01-01
Using the AdS/CFT duality, we study the expectation value of stress tensor in squeezed vacuum states of $2+1$-dimensional quantum critical theories with a general dynamical scaling $z$. The holographic dual theory is the theory of gravity in 3+1-dimensional Lifshitz backgrounds. We then adopt a consistent approach to obtain the boundary stress tensor from bulk construction, which satisfies the trace Ward identity associated with Lifshitz scaling symmetry. The scheme for holographic dual of squeezed vacuum states is found to be the gravity theory in the geometry perturbed by gravitational wave. For small squeezing parameters, the expectation value of stress tensor in squeezed vacuum states is obtained for both strongly coupled quantum critical fields and free relativistic fields. We find that, in both cases with $z=1$, the stress tensor satisfies the averaged null energy condition and is consistent with the quantum interest conjecture. In particular, the negative lower bound on null-contracted stress tensor, w...
Conceptual design of the ALADDIN Antarctic nulling interferometer
Barillot, Marc; Courteau, Pascal; Absil, Olivier; Coudé du Foresto, Vincent; Swain, Mark
2006-06-01
It is commonly accepted that highly challenging planet finding missions such as Darwin and TPF need precursors on the ground, for both technological demonstration and study of the exozodiacal clouds around potential targets. A first instrument, GENIE, designed to be implemented in the interferometric laboratory of the VLTI, was studied by ESA and scientific/industrial teams. In this paper we present a concept for ALADDIN, an operational nulling instrument to be implemented at Dome C in Antarctica, and discuss the comparison with GENIE from the instrumental point of view. Our preliminary design involves moderate ~1m size telescopes mounted on a 40m long rotating beam allowing baselines up to 30m and feeding a 2-arm nulling beam combiner. When compared to GENIE, the rotating beam design has the advantage of removing the need for both long-stroke delay line and dispersion control equipments. As a side effect, the instrumental arrangement of ALADDIN finds itself more representative of what Darwin will be. Furthermore, critical issues like phase control, photometric balance and instrumental background suppression are expected to be relaxed by the improved atmospheric conditions, lower temperature, and simpler optical trains. Calibration of geometrical stellar leakage will make advantage of the continuously adjustable baseline. As results, a simpler instrument showing improved performance is expected. In conclusion, we see our ALADDIN concept as a valuable alternative to GENIE, with a quite stronger scientific potential and a considerably simplified instrumental design.
Adding light to the gravitational waves on the null cone
Babiuc, Maria
2014-03-01
Recent interesting astrophysical observations point towards a multi-messenger, multi-wavelength approach to understanding strong gravitational sources, like compact stars or black hole collisions, supernovae explosions, or even the big bang. Gravitational radiation is properly defined only at future null infinity, but usually is estimated at a finite radius, and then extrapolated. Our group developed a characteristic waveform extraction tool, implemented in an open source code, which computes the gravitational waves infinitely far from their source, in terms of compactified null cones, by numerically solving Einstein equation in Bondi space-time coordinates. The goal is extend the capabilities of the code, by solving Einstein-Maxwell's equations together with the Maxwell's equations, to obtain the energy radiated asymptotically at infinity, both in gravitational and electromagnetic waves. The purpose is to analytically derive and numerically calculate both the gravitational waves and the electromagnetic counterparts at infinity, in this characteristic framework. The method is to treat the source of gravitational and electromagnetic radiation as a black box, and therefore the code will be very flexible, with potentially large applicability.
Does horizon entropy satisfy a Quantum Null Energy Conjecture?
Fu, Zicao
2016-01-01
A modern version of the idea that the area of event horizons gives $4G$ times an entropy is the Hubeny-Rangamani Causal Holographic Information (CHI) proposal for holographic field theories. Given a region $R$ of a holographic QFTs, CHI computes $A/4G$ on a certain cut of an event horizon in the gravitational dual. The result is naturally interpreted as a coarse-grained entropy. CHI is known to be finitely greater than the fine-grained Hubeny-Rangamani-Takayanagi (HRT) entropy when $\\partial R$ lies on a Killing horizon of the QFT spacetime, and in this context satisfies other non-trivial properties expected of an entropy. Here we present evidence that it also satisfies the quantum null energy condition (QNEC), which bounds the second derivative of the entropy of a quantum field theory on one side of a non-expanding null surface by the flux of stress-energy across the surface. In particular, we show CHI to satisfy the QNEC in 1+1 holographic CFTs when evaluated in states dual to conical defects in AdS$_3$. Th...
Null weak values in multi-level systems
International Nuclear Information System (INIS)
A two-step measurement protocol of a quantum system, known as the weak value (WV), was introduced more than two decades ago by Aharonov et al (1988 Phys. Rev. Lett. 60 1351) and has since then been studied in various contexts. In this paper, we discuss another two-step measurement protocol that we dub the null weak value (NWV). The protocol consists of a partial-collapse measurement followed by quantum manipulation on the system and finally a strong measurement. The first step is a strong measurement which takes place with a small probability. The second strong measurement is used as a postselection on the outcome of the earlier step. Not being measured in the partial-collapse stage (null outcome) leads to a nontrivial correlation between the two measurements. The NVW protocol, first defined for a two-level system (Zilberberg et al 2012 arXiv:1205.3877), is then generalized to a multi-level system and compared with the standard-WV protocol.
Non-dissipative electromagnetic media with two Lorentz null cones
International Nuclear Information System (INIS)
We study Maxwell’s equations on a 4-manifold where the electromagnetic medium is modeled by an antisymmetric (2/2 )-tensor with 21 real coefficients. In this setting the Fresnel surface is a fourth-order polynomial surface that describes the dynamical response of the medium in the geometric optics limit. For example, in an isotropic medium the Fresnel surface is a Lorentz null cone. The contribution of this paper is the pointwise description of all electromagnetic medium tensors κ with real coefficients that satisfy the following three conditions: (i)medium κ is invertible, (ii)medium κ is skewon-free, or non-dissipative, (iii)the Fresnel surface of κ is the union of two distinct Lorentz null cones. We show that there are only three classes of media with these properties and give explicit expressions in local coordinates for each class. - Highlights: ► We find two new electromagnetic media classes for which the Fresnel surface decomposes into two light cones. ► In a suitable setting we classify all electromagnetic media where this is the case. ► We find an electromagnetic medium tensor with three different signal speeds in one direction. ► The work is related to [5], which classifies all media with one light cone (in a suitable setting).
Exoplanet detection and characterization via parallel broadband nulling coronagraphy
Hicks, Brian A.
2016-01-01
The contrast and angular resolution required to directly image and characterize mature exoplanetary systems place stringent requirements on the space-based telescopes and starlight suppression systems needed to study spatial distributions of debris disks, exozodiacal dust, and individual planets at multiple epochs in their orbits. A nulling interferometer (nuller) is a coronagraphic suppression system that can be used with all telescope types, including those with obscured and segmented apertures envisioned for upcoming and future observatories. One of the challenges for detection and characterization of exoplanetary signals is achieving high contrast with broad spectral coverage. This work presents design concepts for broadband nulling over four parallel ˜20% bandpasses spanning the visible spectrum. Contrast-limiting effects of stellar angular extent, residual chromaticity of broadband phase shifters, and aperture diffraction are considered to reach simultaneous ≲2×10-8 contrast over separations spanning 0.2 to 0.9 arc sec for a 2.4-m telescope observing a Sun-like star at 10 pc. With added dark hole wavefront control and postprocessing point spread function subtraction techniques to further reduce scattered starlight, such a system could be capable of detecting the very the nearest Earth-like exoplanets and spectral characterization of several nearby extrasolar gas giants.
Benesch, Johan; Askendal, A.; Tengvall, P.
2000-01-01
Radioimmunoassay (RIA) and null ellipsometry are two common methods to quantify adsorbed proteins. However, the accuracy of null ellipsometry with a constant protein refractive index (n 1.465, k 0) at l 632.8 nm has this far not been explored. The present study compared the methods, and the degree of agreement between the simplified single wavelength null ellipsometry and RIA to quantify adsorbed proteins was explored on different surfaces. The quantification methods agreed well w...
TRPV1-null mice are protected from diet-induced obesity
Motter, Arianne L.; Ahern, Gerard P.
2008-01-01
We explored a role for the capsaicin receptor TRPV1 in the regulation of feeding and body mass. On a 4.5% fat diet, wild-type and TRPV1-null mice gained equivalent body mass. On an 11% fat diet, however, TRPV1-null mice gained significantly less mass and adiposity; at 44 weeks the mean body weights of wild-type and TRPV1-null mice were ~51 and 34 g respectively. Both groups of mice consumed equivalent energy and absorbed similar amounts of lipids. TRPV1-null mice, however, exhibited a signifi...
Does anomalous violation of null energy condition invalidate holographic c-theorem?
International Nuclear Information System (INIS)
Null energy condition plays a crucial role in holographic renormalization group flow, leading to the holographic c-theorem. Unfortunately, the null energy condition is quantum mechanically violated. Even the averaged version can be violated. We discuss how the anomalous violation of the null energy condition affects the holographic renormalization group flow in (1+3)-dimensional bulk gravity. We show that despite the violation of the null energy condition, a suitably modified holographic c-function with a peculiar log correction is still monotonically decreasing in so far as we add the counterterm that removes a ghost mode of gravity
Principles: when there should be no difference--how to fail to reject the null hypothesis.
Lew, Michael J
2006-05-01
It is common to perform experiments in which a 'success' is claimed when the null hypothesis is discarded. However, there is a category of experiment that has become important in which a success is when the null hypothesis is not rejected. Failing to discard the null hypothesis is different from proving it to be valid, a distinction that is particularly important in experiments in which any inadequacy of experimental design or implementation enhances the likelihood of a success. The appropriate analysis of such experiments tests for evidence of the validity of the null hypothesis rather than simply failing to find evidence against it. PMID:16595154
Review of OCA activities on nulling testbench PERSEE
Hénault, François; Girard, Paul; Marcotto, Aurélie; Mauclert, Nicolas; Bailet, Christophe; Clausse, Jean-Michel; Mourard, Denis; Rabbia, Yves; Roussel, Alain; Barillot, Marc; Cassaing, Frédéric; Le Duigou, Jean-Michel
2010-07-01
We present a review of our activities on PERSEE (Pégase Experiment for Research and Stabilization of Extreme Extinction) at Observatoire de la Côte d'Azur (OCA). PERSEE is a laboratory testbench aiming at achieving a stabilized nulling ratio better than 10-4 in the astronomical bands K and M, in presence of flight-representative spacecraft perturbations. The bench has been jointly developed by a Consortium of six French institutes and companies, among which OCA was responsible for the star simulator and of the opto-mechanical studies, procurement and manufacturing of the optical train. In this communication are presented the alignment and image quality requirements and the optomechanical design of the illumination module and main optical train, including a periscope Achromatic Phase Shifter (APS), tip-tilt mirrors used to introduce and then compensate for dynamic disturbances, delay lines, beam compressors and fiber injection optics. Preliminary test results of the star simulator are also provided.
'Peeling property' for linearized gravity in null coordinates
International Nuclear Information System (INIS)
A complete description of the linearized gravitational field on a flat background is given in terms of gauge-independent quasilocal quantities. This is an extension of the results from [16]. Asymptotic spherical quasilocal parameterization of the Weyl field and its relation with Einstein equations is presented. The field equations are equivalent to the wave equation. A generalization for the Schwarzschild background is developed and the axial part of the gravitational field is fully analysed. In the case of axial degrees of freedom for the linearized gravitational field the corresponding generalization of the d'Alembert operator is a Regge-Wheeler equation. Finally, the asymptotics at null infinity are investigated and the strong peeling property for axial waves is proved
Radiation Hardened NULL Convention Logic Asynchronous Circuit Design
Directory of Open Access Journals (Sweden)
Liang Zhou
2015-10-01
Full Text Available This paper proposes a radiation hardened NULL Convention Logic (NCL architecture that can recover from a single event latchup (SEL or single event upset (SEU fault without deadlock or any data loss. The proposed architecture is analytically proved to be SEL resistant, and by extension, proved to be SEU resistant. The SEL/SEU resistant version of a 3-stage full-word pipelined NCL 4 × 4 unsigned multiplier was implemented using the IBM cmrf8sf 130 nm 1.2 V process at the transistor level and simulated exhaustively with SEL fault injection to validate the proposed architectures. Compared with the original version, the SEL/SEU resilient version has 1.31× speed overhead, 2.74× area overhead, and 2.79× energy per operation overhead.
Horizons in matter: black hole hair vs. Null Big Bang
Bronnikov, K A
2009-01-01
It is shown that only particular kinds of matter (in terms of the "radial" pressure to density ratio $w$) can coexist with Killing horizons in black-hole or cosmological space-times. Thus, for arbitrary (not necessarily spherically symmetric) static black holes, admissible are vacuum matter ($w=-1$, i.e., the cosmological constant or some its generalization) and matter with certain values of $w$ between 0 and -1, in particular, a gas of disordered cosmic strings ($w=-1/3$). If the cosmological evolution starts from a horizon (the so-called Null Big Bang scenarios), this horizon can co-exist with vacuum matter and certain kinds of phantom matter with $w\\geq -3$. It is concluded that normal matter in such scenarios is entirely created from vacuum.
Linearized gravitational waves near space-like and null infinity
Beyer, Florian; Frauendiener, Jörg; Whale, Ben
2013-01-01
Linear perturbations on Minkowski space are used to probe numerically the remote region of an asymptotically flat space-time close to spatial infinity. The study is undertaken within the framework of Friedrich's conformal field equations and the corresponding conformal representation of spatial infinity as a cylinder. The system under consideration is the (linear) zero-rest-mass equation for a spin-2 field. The spherical symmetry of the underlying background is used to decompose the field into separate non-interacting multipoles. It is demonstrated that it is possible to reach null-infinity from initial data on an asymptotically Euclidean hyper-surface and that the physically important radiation field can be extracted accurately on $\\scri^+$.
A new interferometer architecture combining nulling with phase closure measurements
Lacour, S; Monnier, J D; Kotani, T; Gauchet, L; Labeye, P
2013-01-01
Imaging the direct light signal from a faint exoplanet against the overwhelming glare of its host star presents one of the fundamental challenges to modern astronomical instrumentation. Achieving sufficient signal-to-noise for detection by direct imaging is limited by three basic physical processes: aberration of the wavefronts (both instrumental and atmospheric), photon noise, and detector noise. In this paper, we advance a novel optical setup which synthesizes the advantages of two different techniques: nulling interferometry to mitigate photon noise, and closure phase to combat optical aberrations. Our design, which employs technology from integrated optics and photonics, is intended to combine the advantageous aspects of both a coronagraph and a non-redundant interferometer. We show that such an instrument would allow readout noise limited detection of exoplanets, even in the presence of residual co-phasing errors. As a result, this concept would be ideal for space interferometry and for ground based obse...
Area, Entanglement Entropy and Supertranslations at Null Infinity
Kapec, Daniel; Strominger, Andrew
2016-01-01
The area of a cross-sectional cut $\\Sigma$ of future null infinity ($\\mathcal{I}^+$) is infinite. We define a finite, renormalized area by subtracting the area of the same cut in any one of the infinite number of BMS-degenerate classical vacua. The renormalized area acquires an anomalous dependence on the choice of vacuum. We relate it to the modular energy, including a soft graviton contribution, of the region of $\\mathcal{I}^+$ to the future of $\\Sigma$. Under supertranslations, the renormalized area shifts by the supertranslation charge of $\\Sigma$. In quantum gravity, we conjecture a bound relating the renormalized area to the entanglement entropy across $\\Sigma$ of the outgoing quantum state on $\\mathcal{I}^+$.
Power spectrum nulls due to nonstandard inflationary evolution
Goswami, Gaurav; Souradeep, Tarun
2011-01-01
The simplest models of inflation based on slow roll produce nearly scale invariant primordial power spectra (PPS). But there are also numerous models that predict radically broken scale invariant PPS. In particular, markedly cuspy dips in the PPS correspond to nulls where the perturbation amplitude, hence PPS, goes through a zero at a specific wave number. Near this wave number, the true quantum nature of the generation mechanism of the primordial fluctuations may be revealed. Naively these features may appear to arise from fine-tuned initial conditions. However, we show that this behavior arises under fairly generic set of conditions involving super-Hubble scale evolution of perturbation modes during inflation. We illustrate this with the well-studied examples of punctuated inflation and the Starobinsky-break model.
Power spectrum nulls due to non-standard inflationary evolution
Goswami, Gaurav
2010-01-01
The simplest models of inflation based on slow roll produce nearly scale invariant primordial power spectra (PPS). But there are also numerous models that predict radically broken scale invariant PPS. In particular, markedly cuspy dips in the PPS correspond to nulls where the perturbation amplitude, hence PPS, goes through a zero at a specific wavenumber. Near this wavenumber, the true quantum nature of the generation mechanism of the primordial fluctuations may be revealed. Naively these features may appear to arise from fine tuned initial conditions. However, we show that this behavior arises under fairly generic set of conditions involving super-Hubble scale evolution of perturbation modes during inflation. We illustrate this with the well-studied examples of punctuated inflation and the Starobinsky-break model.
From Satisfying to Violating the Null Energy Condition
Elder, Benjamin; Khoury, Justin
2013-01-01
We construct a theory which admits a time-dependent solution smoothly interpolating between a null energy condition (NEC)-satisfying phase at early times and a NEC-violating phase at late times. We first review earlier attempts to violate the NEC and an argument of Rubakov, presented in 1305.2614, which forbids the existence of such interpolating solutions in a single-field dilation-invariant theory. We then construct a theory which, in addition to possessing a Poincar\\'e-invariant vacuum, does admit such a solution. For a wide range of parameters, perturbations around this solution are at all times stable, comfortably subluminal and weakly-coupled. The theory requires us to explicitly break dilation-invariance, so it is unlikely that the theory is fully stable under quantum corrections, but we argue that the existence of a healthy interpolating solution is quantum-mechanically robust.
Null-stream pointing with pulsar timing arrays
Hazboun, Jeffrey S
2016-01-01
Locating sources on the sky is one of the largest challenges in gravitational wave astronomy, owing to the omni-directional nature of gravitational wave detection techniques, and the often intrinsically weak signals being observed. Ground-based detectors can address the pointing problem by observing with a network of detectors, effectively triangulating signal locations by observing the arrival times across the network. Space-based detectors will observe long-lived sources that persist while the detector moves relative to their location on the sky, using Doppler shifts of the signal to locate the sky position. While these methods improve the pointing capability of a detector or network, the angular resolution is still coarse compared to the standards one expects from electromagnetic astronomy. Another technique that can be used for sky localization is null-stream pointing. In the case where multiple independent data streams exist, a single astrophysical source of gravitational waves will appear in each of the...
Null polarimetry near shot noise limit at 1 Hz
He, Dechao; Xie, Boya; Feng, Sheng
2016-04-01
We describe the principle and report on the realization of a null polarimeter with two demonstrated features: (1) the sensitivity of the system is near shot noise limit and (2) quasi-stationary signals at 1 Hz can be measured without signal modulation. The achieved single-pass sensitivity is 7 × 10-9 rad/ √{ Hz } with a pair of Glan-Taylor polarizers, which should be of great interest for experiments such as observation of vacuum magnetic birefringence and search for new particles. The system is brought near its shot noise limit by appropriate polarization control and coherent heterodyne detection of light, resulting in a sensitivity improvement by two orders of magnitude in comparison with the case of no control on light polarization.
Molecular bass for a malic enzyme null mutation
International Nuclear Information System (INIS)
Many tissues from normal (wt) mice have cytosolic malic enzyme (ME) activity and express two mRNAs (2 and 3.1 kb) that code for a single ME polypeptide. Mod-1 null (M-n) mice lack cytosolic ME activity, but express 2.5 and 3.6 kb mRNAs that hybridize with wt ME cDNAs. To investigate the basis for the ME deficiency cDNAs corresponding to M-n ME RNA were cloned. A λgt11 library was prepared using M-n liver mRNA as a template. Wt ME cDNA probes hybridized with several recombinant phages and a 2kb insert with an atypical (non-wt) restriction pattern was subcloned in pGEM 1 and sequenced. The M-n ME cDNA contains an internal directly repeated sequence that corresponds to nts 1109-1617 in the coding region of wt ME cDNA. A restriction fragment from M-n ME cDNA that includes the first 204 bp of repeated sequence and 306 bp of contiguous 5' sequence was subcloned into pGEM 1 and used as a template for synthesizing 32P-labeled anti-sense RNA. After hybridization with M-n liver RNA the 510 nt transcript was resistant to RNA digestion; after hybridization with wt RNA only fragments corresponding to the normally non-contiguous 204 bp and 306 bp segments of the insert were protected. Thus the partial duplication of coding sequence in M-n ME mRNA is confirmed. Analyses of intron-exon organization in the relevant regions of the wt and M-n ME genes will provide further insights into the mechanism underlying the ME null mutation
Cadmium modulates adipocyte functions in metallothionein-null mice
International Nuclear Information System (INIS)
Our previous study has demonstrated that exposure to cadmium (Cd), a toxic heavy metal, causes a reduction of adipocyte size and the modulation of adipokine expression. To further investigate the significance of the Cd action, we studied the effect of Cd on the white adipose tissue (WAT) of metallothionein null (MT−/−) mice, which cannot form atoxic Cd–MT complexes and are used for evaluating Cd as free ions, and wild type (MT+/+) mice. Cd administration more significantly reduced the adipocyte size of MT−/− mice than that of MT+/+ mice. Cd exposure also induced macrophage recruitment to WAT with an increase in the expression level of Ccl2 (MCP-1) in the MT−/− mice. The in vitro exposure of Cd to adipocytes induce triglyceride release into culture medium, decrease in the expression levels of genes involved in fatty acid synthesis and lipid hydrolysis at 24 h, and at 48 h increase in phosphorylation of the lipid-droplet-associated protein perilipin, which facilitates the degradation of stored lipids in adipocytes. Therefore, the reduction in adipocyte size by Cd may arise from an imbalance between lipid synthesis and lipolysis. In addition, the expression levels of leptin, adiponectin and resistin decreased in adipocytes. Taken together, exposure to Cd may induce unusually small adipocytes and modulate the expression of adipokines differently from the case of physiologically small adipocytes, and may accelerate the risk of developing insulin resistance and type 2 diabetes. - Highlights: • Cd causes a marked reduction in adipocyte size in MT-null mice. • Cd enhances macrophage migration into adipose tissue and disrupt adipokine secretion. • MT gene alleviates Cd-induced adipocyte dysfunctions. • Cd enhances the degradation of stored lipids in adipocytes, mediated by perilipin. • Cd induces unusually small adipocytes and the abnormal expression of adipokines
Cadmium modulates adipocyte functions in metallothionein-null mice
Energy Technology Data Exchange (ETDEWEB)
Kawakami, Takashige; Nishiyama, Kaori; Kadota, Yoshito; Sato, Masao; Inoue, Masahisa; Suzuki, Shinya, E-mail: suzukis@ph.bunri-u.ac.jp
2013-11-01
Our previous study has demonstrated that exposure to cadmium (Cd), a toxic heavy metal, causes a reduction of adipocyte size and the modulation of adipokine expression. To further investigate the significance of the Cd action, we studied the effect of Cd on the white adipose tissue (WAT) of metallothionein null (MT{sup −/−}) mice, which cannot form atoxic Cd–MT complexes and are used for evaluating Cd as free ions, and wild type (MT{sup +/+}) mice. Cd administration more significantly reduced the adipocyte size of MT{sup −/−} mice than that of MT{sup +/+} mice. Cd exposure also induced macrophage recruitment to WAT with an increase in the expression level of Ccl2 (MCP-1) in the MT{sup −/−} mice. The in vitro exposure of Cd to adipocytes induce triglyceride release into culture medium, decrease in the expression levels of genes involved in fatty acid synthesis and lipid hydrolysis at 24 h, and at 48 h increase in phosphorylation of the lipid-droplet-associated protein perilipin, which facilitates the degradation of stored lipids in adipocytes. Therefore, the reduction in adipocyte size by Cd may arise from an imbalance between lipid synthesis and lipolysis. In addition, the expression levels of leptin, adiponectin and resistin decreased in adipocytes. Taken together, exposure to Cd may induce unusually small adipocytes and modulate the expression of adipokines differently from the case of physiologically small adipocytes, and may accelerate the risk of developing insulin resistance and type 2 diabetes. - Highlights: • Cd causes a marked reduction in adipocyte size in MT-null mice. • Cd enhances macrophage migration into adipose tissue and disrupt adipokine secretion. • MT gene alleviates Cd-induced adipocyte dysfunctions. • Cd enhances the degradation of stored lipids in adipocytes, mediated by perilipin. • Cd induces unusually small adipocytes and the abnormal expression of adipokines.
National Oceanic and Atmospheric Administration, Department of Commerce — Through the study of faults and their effects, much can be learned about the size and recurrence intervals of earthquakes. Faults also teach us about crustal...
Agreement and Null Subjects in German L2 Development: New Evidence from Reaction-Time Experiments.
Clahsen, Harald; Hong, Upyong
1995-01-01
Reports on reaction time experiments investigating subject-verb agreement and null subjects in 33 Korean learners of German and a control group of 20 German native speakers. Results found that the two phenomena do not covary in the Korean learners, indicating that properties of agreement and null subjects are acquired separately from one another.…
Exact null-controllability of interconnected abstract evolution systems by scalar force motion
Shklyar, B.
2013-01-01
The paper deals with exact null-controllability problem for a linear control system consisting of two serially connected abstract control systems. Controllability conditions are obtained. Applications to the exact null-controllability for interconnected control system of heat and wave equations are considered.
Alpha-null defocus: An optimum defocus condition with relevance for focal-series reconstruction
Energy Technology Data Exchange (ETDEWEB)
O' Keefe, Michael A.
2001-02-14
Two optimum defocus conditions are used in high-resolution transmission electron microscopy. Scherzer defocus produces an image of the specimen ''projected potential'' to the resolution of the microscope, and Lichte defocus minimizes dispersion. A third optimum defocus is best for focal-series reconstruction; alpha-null defocus maximizes transfer of high-frequency diffracted beam amplitudes into the microscope image. Beam transfer is confined by incident-beam convergence to a Gaussian ''packet'' of defocus values centered on the alpha-null defocus. For a diffracted beam hkl, with a spatial frequency of u, the envelope for incident beam convergence has null damping effect when defocus is set to -Cs. (wavelength.u)**2. On either side of this alpha-null defocus value, the damping effect of incident-beam convergence reduces diffracted-beam transfer. The position of alpha-null defocus for any spatial frequency depends only on the value of Cs, but defocus-packet width around the alpha-null defocus depends only on the convergence semi-angle. Under NCEM OAM (one-Angstrom microscope) conditions, a [110] diamond image with the correct 0.89A spacing appears when the Si (004) alpha-null defocus is selected. The alpha-null defocus should be included as the (furthest underfocus) limit for all high-resolution focal series reconstruction.
International Nuclear Information System (INIS)
Full text: Calculational methods and Reduce software are described for determining polyhomogeneous asymptotic expansions of solutions of Einstein's equations in null characteristic transport form. As an example, results concerning peeling of gravitational radiation in Null Quasi-Spherical (NQS) spacetimes are presented
Null controllability of the viscous Camassa–Holm equation with moving control
Indian Academy of Sciences (India)
Peng Gao
2016-02-01
In this paper, we study the null controllability of the viscous Camassa–Holm equation on the one-dimensional torus. By using a moving distributed control, we obtain that the system is null controllable for a given data with certain regularity.
A trilinear method for finding null points in a three-dimensional vector space
International Nuclear Information System (INIS)
Null points are important locations in vector fields, such as a magnetic field. A new technique (a trilinear method for finding null points) is presented for finding null points over a large grid of points, such as those derived from a numerical experiment. The method was designed so that the null points found would agree with any field lines traced using the commonly used trilinear interpolation. It is split into three parts: reduction, analysis, and positioning, which, when combined, provide an efficient means of locating null points to a user-defined subgrid accuracy. We compare the results of the trilinear method with that of a method based on the Poincare index, and discuss the accuracy and limitations of both methods
Spacetime characterizations of $\\Lambda$-vacuum metrics with a null Killing 2-form
Mars, Marc
2016-01-01
An exhaustive list of four-dimensional $\\Lambda$-vacuum spacetimes admitting a Killing vector whose self-dual Killing two-form ${\\cal F}$ is null is obtained assuming that the self-dual Weyl tensor is proportional to the tensor product of ${\\cal F}$ by itself. Our analysis complements previous results concerning the case with non-null ${\\cal F}$. We analyze both cases with $\\Lambda$ vanishing or not. In the latter case we prove that $\\Lambda< 0$ must hold necessarily, and we find a characterization of the Einstein spacetimes conformal to pp-waves. In the former case we obtain spacetime characterizations of vacuum plane waves and of the stationary vacuum Brinkmann spacetimes. At the light of the full set of results, old and new, we reformulate the case with non-null ${\\cal F}$ and $\\Lambda= 0$. We finally present a table collecting the results for both null, and non-null, ${\\cal F}$.
Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent.
Directory of Open Access Journals (Sweden)
Jane Q Chen
Full Text Available Female 129:Stat1-null mice (129S6/SvEvTac-Stat1(tm1Rds homozygous uniquely develop estrogen-receptor (ER-positive mammary tumors. Herein we report that the mammary glands (MG of these mice have altered growth and development with abnormal terminal end buds alongside defective branching morphogenesis and ductal elongation. We also find that the 129:Stat1-null mammary fat pad (MFP fails to sustain the growth of 129S6/SvEv wild-type and Stat1-null epithelium. These abnormalities are partially reversed by elevated serum progesterone and prolactin whereas transplantation of wild-type bone marrow into 129:Stat1-null mice does not reverse the MG developmental defects. Medium conditioned by 129:Stat1-null epithelium-cleared MFP does not stimulate epithelial proliferation, whereas it is stimulated by medium conditioned by epithelium-cleared MFP from either wild-type or 129:Stat1-null females having elevated progesterone and prolactin. Microarrays and multiplexed cytokine assays reveal that the MG of 129:Stat1-null mice has lower levels of growth factors that have been implicated in normal MG growth and development. Transplanted 129:Stat1-null tumors and their isolated cells also grow slower in 129:Stat1-null MG compared to wild-type recipient MG. These studies demonstrate that growth of normal and neoplastic 129:Stat1-null epithelium is dependent on the hormonal milieu and on factors from the mammary stroma such as cytokines. While the individual or combined effects of these factors remains to be resolved, our data supports the role of STAT1 in maintaining a tumor-suppressive MG microenvironment.
Why Are Flare Ribbons Associated with the Spines of Magnetic Null Points Generically Elongated?
Pontin, David; Galsgaard, Klaus; Démoulin, Pascal
2016-08-01
Coronal magnetic null points exist in abundance, as demonstrated by extrapolations of the coronal field, and have been inferred to be important for a broad range of energetic events. These null points and their associated separatrix and spine field lines represent discontinuities of the field line mapping, making them preferential locations for reconnection. This field line mapping also exhibits strong gradients adjacent to the separatrix (fan) and spine field lines, which can be analysed using the "squashing factor", Q. In this article we analyse in detail the distribution of Q in the presence of magnetic nulls. While Q is formally infinite on both the spine and fan of the null, the decay of Q away from these structures is shown in general to depend strongly on the null-point structure. For the generic case of a non-radially-symmetric null, Q decays most slowly away from the spine or fan in the direction in which |{B}| increases most slowly. In particular, this demonstrates that the extended elliptical high-Q halo around the spine footpoints observed by Masson et al. ( Astrophys. J. 700, 559, 2009) is a generic feature. This extension of the Q halos around the spine or fan footpoints is important for diagnosing the regions of the photosphere that are magnetically connected to any current layer that forms at the null. In light of this, we discuss how our results can be used to interpret the geometry of observed flare ribbons in circular ribbon flares, in which typically a coronal null is implicated. We conclude that both the physics in the vicinity of the null and how this is related to the extension of Q away from the spine or fan can be used in tandem to understand observational signatures of reconnection at coronal null points.
Why Are Flare Ribbons Associated with the Spines of Magnetic Null Points Generically Elongated?
Pontin, David; Galsgaard, Klaus; Démoulin, Pascal
2016-06-01
Coronal magnetic null points exist in abundance, as demonstrated by extrapolations of the coronal field, and have been inferred to be important for a broad range of energetic events. These null points and their associated separatrix and spine field lines represent discontinuities of the field line mapping, making them preferential locations for reconnection. This field line mapping also exhibits strong gradients adjacent to the separatrix (fan) and spine field lines, which can be analysed using the "squashing factor", Q. In this article we analyse in detail the distribution of Q in the presence of magnetic nulls. While Q is formally infinite on both the spine and fan of the null, the decay of Q away from these structures is shown in general to depend strongly on the null-point structure. For the generic case of a non-radially-symmetric null, Q decays most slowly away from the spine or fan in the direction in which |{B}| increases most slowly. In particular, this demonstrates that the extended elliptical high- Q halo around the spine footpoints observed by Masson et al. (Astrophys. J. 700, 559, 2009) is a generic feature. This extension of the Q halos around the spine or fan footpoints is important for diagnosing the regions of the photosphere that are magnetically connected to any current layer that forms at the null. In light of this, we discuss how our results can be used to interpret the geometry of observed flare ribbons in circular ribbon flares, in which typically a coronal null is implicated. We conclude that both the physics in the vicinity of the null and how this is related to the extension of Q away from the spine or fan can be used in tandem to understand observational signatures of reconnection at coronal null points.
Strong subadditivity, null energy condition and charged black holes
International Nuclear Information System (INIS)
Using the Hubeny-Rangamani-Takayanagi (HRT) conjectured formula for entanglement entropy in the context of the AdS/CFT correspondence with time-dependent backgrounds, we investigate the relation between the bulk null energy condition (NEC) of the stress-energy tensor with the strong sub-additivity (SSA) property of entanglement entropy in the boundary theory. In a background that interpolates between an AdS to an AdS-Reissner-Nordstrom-type geometry, we find that generically there always exists a critical surface beyond which the violation of NEC would naively occur. However, the extremal area surfaces that determine the entanglement entropy for the boundary theory, can penetrate into this forbidden region only for certain choices for the mass and the charge functions in the background. This penetration is then perceived as the violation of SSA in the boundary theory. We also find that this happens only when the critical surface lies above the apparent horizon, but not otherwise. We conjecture that SSA, which is thus non-trivially related to NEC, also characterizes the entire time-evolution process along which the dual field theory may thermalize
On the Null Energy Condition and Causality in Lifshitz Holography
Hoyos, Carlos
2010-01-01
We use a WKB approximation to establish a relation between the wavefront velocity in a strongly coupled theory and the local speed of light in a holographic dual, with our main focus put on systems with Lifshitz scaling with dynamical exponent z. We then use Einstein equations to relate the behavior of the local speed of light in the bulk with the null energy condition (NEC) for bulk matter, and we show that it is violated for Lifshitz backgrounds with z<1. We study signal propagation in the gravity dual and show that violations of the NEC are incompatible with causality in the strongly coupled theory, ruling out as holographic models Lifshitz backgrounds with z<1. We argue that causality violations in z<1 theories will show up in correlators as superluminal modes and confirm this for a particular example with z=1/2. Finally, as an application, we use z<1 solutions to uncover regions of the parameter space of curvature squared corrections to gravity where the NEC can be violated.
Aspects of QCD Current Algebra on a Null Plane
Beane, Silas R
2015-01-01
Consequences of QCD current algebra formulated on a light-like hyperplane are derived for the forward scattering of vector and axial-vector currents on an arbitrary hadronic target. It is shown that current algebra gives rise to a special class of sum rules that are direct consequences of the independent chiral symmetry that exists at every point on the two-dimensional transverse plane orthogonal to the lightlike direction. These sum rules are obtained by exploiting the closed, infinite-dimensional algebra satisfied by the transverse moments of null-plane axial-vector and vector charge distributions. In the special case of a nucleon target, this procedure leads to the Adler-Weisberger, Gerasimov-Drell-Hearn, Cabbibo-Radicatti and Fubini-Furlan-Rossetti sum rules. Matching to the dispersion-theoretic language which is usually invoked in deriving these sum rules, the moment sum rules are shown to be equivalent to algebraic constraints on forward S-matrix elements in the Regge limit.
Impairment in motor learning of somatostatin null mutant mice.
Zeyda, T; Diehl, N; Paylor, R; Brennan, M B; Hochgeschwender, U
2001-07-01
Somatostatin was first identified as a hypothalamic factor which inhibits the release of growth hormone from the anterior pituitary (somatotropin release inhibitory factor, SRIF). Both SRIF and its receptors were subsequently found widely distributed within and outside the nervous system, in the adult as well as in the developing organism. Reflecting this wide distribution, somatostatin has been implicated regulating a diverse array of biological processes. These include body growth, homeostasis, sensory perception, autonomous functions, rate of intestinal absorption, behavior, including cognition and memory, and developmental processes. We produced null mutant mice lacking somatostatin through targeted mutagenesis. The mutant mice are healthy, fertile, and superficially indistinguishable from their heterozygous and wildtype littermates. A 'first round' phenotype screen revealed that mice lacking somatostatin have elevated plasma growth hormone levels, despite normal body size, and have elevated basal plasma corticosterone levels. In order to uncover subtle and unexpected differences, we carried out a systematic behavioral phenotype screen which identified a significant impairment in motor learning revealed when increased demands were made on motor coordination. Motor coordination and motor learning require an intact cerebellum. While somatostatin is virtually absent from the adult cerebellum, the ligand and its receptor(s) are transiently expressed at high levels in the developing cerebellum. This result suggests the functional significance of transient expression of SRIF and its receptors in the development of the cerebellum. PMID:11430867
Strong Subadditivity, Null Energy Condition and Charged Black Holes
Caceres, Elena; Pedraza, Juan F; Tangarife, Walter
2014-01-01
Using the Hubeny-Rangamani-Takayanagi (HRT) conjectured formula for entanglement entropy in the context of the AdS/CFT correspondence with time-dependent backgrounds, we investigate the relation between the bulk null energy condition (NEC) of the stress-energy tensor with the strong sub-additivity (SSA) property of entanglement entropy in the boundary theory. In a background that interpolates between an AdS to an AdS-Reissner-Nordstrom-type geometry, we find that generically there always exists a critical surface beyond which the violation of NEC would naively occur. However, the extremal area surfaces that determine the entanglement entropy for the boundary theory, can penetrate into this forbidden region only for certain choices for the mass and the charge functions in the background. This penetration is then perceived as the violation of SSA in the boundary theory. We also find that this happens only when the critical surface lies above the apparent horizon, but not otherwise. We conjecture that SSA, which...
Aspects of QCD current algebra on a null plane
Beane, S. R.; Hobbs, T. J.
2016-09-01
Consequences of QCD current algebra formulated on a light-like hyperplane are derived for the forward scattering of vector and axial-vector currents on an arbitrary hadronic target. It is shown that current algebra gives rise to a special class of sum rules that are direct consequences of the independent chiral symmetry that exists at every point on the two-dimensional transverse plane orthogonal to the lightlike direction. These sum rules are obtained by exploiting the closed, infinite-dimensional algebra satisfied by the transverse moments of null-plane axial-vector and vector charge distributions. In the special case of a nucleon target, this procedure leads to the Adler-Weisberger, Gerasimov-Drell-Hearn, Cabibbo-Radicati and Fubini-Furlan-Rossetti sum rules. Matching to the dispersion-theoretic language which is usually invoked in deriving these sum rules, the moment sum rules are shown to be equivalent to algebraic constraints on forward S-matrix elements in the Regge limit.
International Nuclear Information System (INIS)
'Puff and pump' radiating divertor scenarios [1,2] were applied to upper SN and DN H-mode plasmas. Under similar operating conditions, argon (Ar) accumulated in the main plasma of single-null (SN) plasmas more rapidly and reached a higher steady-state concentration when the B x (del)B ion drift direction was toward the divertor than when the B x (del)B ion drift direction was out of the divertor. The initial rate that Ar accumulated inside double-null (DN) plasmas was more than twice that of comparably-prepared SNs with the same B x (del)B direction. One way to reduce power loading at the divertor targets is to 'seed' the divertor plasma with impurities that radiatively reduce the conducted power. Studies have shown that the concentration of impurities in the divertor are increased by raising the flow of deuterium ions (D+) into the divertor by a combination of upstream deuterium gas puffing and active particle exhaust at the divertor targets, i.e., puff-and-pump. An enhanced D+ particle flow toward the divertor targets exerts a frictional drag on impurities, and inhibits their escape from the divertor. A puff-and-pump approach using Ar as the impurity was successfully applied in recent DIII-D experiments to SN plasmas [3] while maintaining good H-mode performance. Studies on DIII-D and other tokamaks have shown that both the direction of the toroidal magnetic field BT and the degree of magnetic balance between divertors [i.e., the degree to which the plasma shape is considered SN or DN] are important factors in determining recycling and particle pumping [4,5]. It is unclear whether the favorable results of Ref. [3] can be extended to cases with different magnetic balance and/or BT direction. We show in this paper that reversing the direction of BT or altering the divertor magnetic balance does have an impact on how plasmas behave under puff-and-pump conditions. Our study takes advantage of DIII-D's capabilities to actively pump SN and DN shapes with high
Why are flare ribbons generically elongated in configurations with magnetic null points?
Pontin, David Iain; Galsgaard, Klaus; Demoulin, Pascal
2016-05-01
Coronal magnetic null points exist in abundance as demonstrated by extrapolations of the coronal field, and have been inferred to be important for a broad range of energetic events. These null points and their associated separatrix and spine field lines represent discontinuities of the field line mapping, making them preferential locations for reconnection in the corona. In addition, the field line mapping in the vicinity of these null points exhibits strong gradients as measured by the “squashing factor”, Q. We demonstrate that the extension of the Q halos around the spine/fan footpoints is in general important for diagnosing the regions of the photosphere that are magnetically connected to any current layer that forms at the null. In light of this, we discuss the extent to which our results can be used to interpret the geometry of observed flare ribbons in events in which a coronal null is implicated. We conclude that together the physics in the vicinity of the null and how this is related to the extension of Q away from the spine/fan can be used in tandem to understand observational signatures of reconnection at coronal null points.
Integrated optics for nulling interferometry in the thermal infrared
Barillot, Marc; Barthelemy, Eleonore; Broquin, Jean-Emmanuel; Frayret, Jérôme; Grelin, Jérôme; Hawkins, Gary; Kirschner, Volker; Parent, Gilles; Pradel, Annie; Rossi, Emmanuel; Vigreux, Caroline; Zhang, Shaoqian; Zhang, Xianghua
2008-07-01
Modal filtering is based on the capability of single-mode waveguides to transmit only one complex amplitude function to eliminate virtually any perturbation of the interfering wavefronts, thus making very high rejection ratios possible in a nulling interferometer. In the present paper we focus on the progress of Integrated Optics in the thermal infrared [6-20μm] range, one of the two candidate technologies for the fabrication of Modal Filters, together with fiber optics. In conclusion of the European Space Agency's (ESA) "Integrated Optics for Darwin" activity, etched layers of chalcogenide material deposited on chalcogenide glass substrates was selected among four candidates as the technology with the best potential to simultaneously meet the filtering efficiency, absolute and spectral transmission, and beam coupling requirements. ESA's new "Integrated Optics" activity started at mid-2007 with the purpose of improving the technology until compliant prototypes can be manufactured and validated, expectedly by the end of 2009. The present paper aims at introducing the project and the components requirements and functions. The selected materials and preliminary designs, as well as the experimental validation logic and test benches are presented. More details are provided on the progress of the main technology: vacuum deposition in the co-evaporation mode and subsequent etching of chalcogenide layers. In addition, preliminary investigations of an alternative technology based on burying a chalcogenide optical fiber core into a chalcogenide substrate are presented. Specific developments of anti-reflective solutions designed for the mitigation of Fresnel losses at the input and output surface of the components are also introduced.
Bhadra, Sanchita; Lozano, Mary M.; Dudley, Jaquelin P.
2008-01-01
The absence of endogenous mouse mammary tumor viruses (MMTVs) in the congenic mouse strain, BALB/Mtv-null, restricts the early steps of exogenous C3H MMTV infection, preventing the superantigen (Sag) response and mammary tumorigenesis. Here we demonstrate that BALB/Mtv-null mice also resist tumor induction by FM MMTV, which encodes a stronger Sag compared to C3H MMTV. In contrast to infections with C3H MMTV, Mtv-null mice show FM-MMTV Sag-specific responses comparable to those observed in sus...
Ueda, R; Tanimoto, M; Takahashi, T.; Ogata, S; Nishida, K; Namikawa, R.; Nishizuka, Y; Ota, K.
1982-01-01
Nine antigens systems were defined. Two were related to HLA-A,B,C and to Ia-like antigens; the others could be grouped into three categories. (i) NL-22, NL-1: NL-22 antibody reacted with leukemia cells from 12 to 16 cases of null cell acute lymphocytic leukemia (null-ALL) but not with any other type of leukemia tested or with lymphoid cells of various origins. Among cultured cell lines tested, one (NALM-6) of three null-ALL cell lines was positive, the others were negative. Absorption analysi...
Institute of Scientific and Technical Information of China (English)
刘惟一
1989-01-01
In this paper the conflict between the null constraints and the set of functional dependencies is defined.Some rules for determining the conflicts and a method for processing the conflicts are obtained.
Current Singularities at Quasi-Separatrix Layers and Three-Dimensional Magnetic Nulls
Craig, I J D
2014-01-01
The open problem of how singular current structures form in line-tied, three-dimensional magnetic fields is addressed. A Lagrangian magneto-frictional relaxation method is employed to model the field evolution towards the final near-singular state. Our starting point is an exact force-free solution of the governing magnetohydrodynamic (MHD) equations which is sufficiently general to allow for topological features like magnetic nulls to be inside or outside the computational domain, depending on a simple set of parameters. Quasi-separatrix layers (QSLs) are present in these structures and together with the magnetic nulls, they significantly influence the accumulation of current. It is shown that perturbations affecting the lateral boundaries of the configuration lead not only to collapse around the magnetic null, but also to significant QSL currents. Our results show that once a magnetic null is present, the developing currents are always attracted to that specific location and show a much stronger scaling wit...
Dynamics-independent null experiment for testing time-reversal invariance
Arash, Firooz; Moravcsik, Michael J.; Goldstein, Gary R.
1985-06-01
It is shown that it is impossible to construct, in any reaction in atomic, nuclear, or particle physics, a null experiment that would unambiguously test the validity of time-reversal invariance independently of dynamical assumptions.
Dynamics-independent null experiment for testing time-reversal invariance
International Nuclear Information System (INIS)
It is shown that it is impossible to construct, in any reaction in atomic, nuclear, or particle physics, a null experiment that would unambiguously test the validity of time-reversal invariance independently of dynamical assumptions
Adaptive nulling: a new tool for the interfoeromic exo-planet detection
Lay, O.; Jeganathan, M.; Peters, R.
2003-01-01
This paper describes the need for a compensator that can adaptively correct for mismatches between the optical beamtrains of a Mid-IR nulling interferometer, across the science bandwidth with a range of spectral dependences.
Entropy of a generic null surface from its associated Virasoro algebra
Chakraborty, Sumanta; Padmanabhan, T
2016-01-01
Null surfaces act as one-way membranes, blocking information from those observers who do not cross them (e.g., in the black hole and the Rindler spacetimes) and these observers associate an entropy (and temperature) with the null surface. The black hole entropy can be computed from the central charge of an appropriately defined, local, Virasoro algebra on the horizon. We show that one can extend these ideas to a general class of null surfaces, all of which possess a Virasoro algebra and a central charge, leading to an entropy density (i.e., per unit area) which is just $(1/4)$. All the previously known results of associating entropy with horizons arise as special cases of this very general property of null surfaces demonstrated here. The implications are discussed.
Vlasov Fluid stability of a 2-D plasma with a linear magnetic field null
International Nuclear Information System (INIS)
Vlasov Fluid stability of a 2-dimensional plasma near an O type magnetic null is investigated. Specifically, an elongated Z-pinch is considered, and applied to Field Reversed Configurations at Los Alamos National Laboratory by making a cylindrical approximation of the compact torus. The orbits near an elliptical O type null are found to be very complicated; the orbits are large and some are stochastic. The kinetic corrections to magnetohydrodynamics (MHD) are investigated by evaluating the expectation values of the growth rates of a Vlasov Fluid dispersion functional by using a set of trial functions based on ideal MHD. The dispersion functional involves fluid parts and orbit dependent parts. The latter involves phase integral of two time correlations. The phase integral is replaced by the time integral both for the regular and for the stochastic orbits. Two trial functions are used; one has a large displacement near the null and the other away from the null
Kahel korral järjest null häält / Maarius Suviste
Suviste, Maarius, 1966-
2005-01-01
Kohalike omavalitsuste volikogude valimistel ei saanud ühtegi häält 233 kandidaati. Oma kandideerimise põhjusi selgitavad juba teist korda valimistel null häält saanud Viljandi tisler Kaljo Jürman, Põlvamaa mahetalunik Liisi Kutkina ja Ida-Virumaa pensionär Vaike Zaitseva. Lisatud statistilised andmed null häält saanud kandidaatide kohta maakondade ja erakondade kaupa
Increased Fibronectin Deposition in Embryonic Hearts of Retinol-Binding Protein–Null Mice
Wendler, Christopher C.; Schmoldt, Angela; Flentke, George R.; Case, Lauren C.; Quadro, Loredana; Blaner, William S.; Lough, John; Susan M. Smith
2003-01-01
Precise regulation of retinoid levels is critical for normal heart development. Retinol-binding protein (RBP), an extracellular retinol transporter, is strongly secreted by cardiogenic endoderm. This study addresses whether RBP gene ablation affects heart development. Despite exhibiting an >85% decrease in serum retinol, adult RBP-null mice are viable, breed, and have normal vision when maintained on a vitamin A-sufficient diet. Comparison of RBP-null with wild-type (WT) hearts from embryos a...
Testing the null hypothesis of no regime switching with an application to GDP growth rates
Marmer, Vadim
2009-01-01
This paper presents tests for the null hypothesis of no regime switching in Hamilton's (1989) regime switching model. The test procedures exploit similarities between regime switching models, autoregressions with measurement errors, and finite mixture models. The proposed tests are computationally simple and, contrary to likelihood based tests, have a standard distribution under the null. When the methodology is applied to US GDP growth rates, no strong evidence of regime switching is found.
Dynamic Stability of Lateral and Yawing Motions in the Double Null-Flux EDS System
Murai, Toshiaki; Yoshioka, Hiroshi; Sugino, Motohiko
The double null-flux electro-dynamic suspension (EDS) in the superconducting maglev has the coupling lateral and yawing stiffness, which does not coincide with each other, so special attention should be paid to the dynamic stability of lateral and yawing motions. This paper describes their intrinsic dynamic stability by analyzing the lateral and yawing motions of bogie levitated by the double null-flux EDS.
Increased Oxidative Stress Impairs Adipose Tissue Function in Sphingomyelin Synthase 1 Null Mice
Masato Yano; Tadashi Yamamoto; Naotaka Nishimura; Tomomi Gotoh; Ken Watanabe; Kazutaka Ikeda; Yohei Garan; Ryo Taguchi; Koichi Node; Toshiro Okazaki; Yuichi Oike
2013-01-01
Sphingomyelin synthase 1 (SMS1) catalyzes the conversion of ceramide to sphingomyelin. Here, we found that SMS1 null mice showed lipodystrophic phenotype. Mutant mice showed up-regulation of plasma triglyceride concentrations accompanied by reduction of white adipose tissue (WAT) as they aged. Lipoprotein lipase (LPL) activity was severely reduced in mutant mice. In vivo analysis indicated that fatty acid uptake in WAT but not in liver decreased in SMS1 null compared to wild-type mice. In vit...
Human Cancer Growth and Therapy In NOD/SCID/IL2Rγnull (NSG) Mice
Shultz, Leonard D.; Goodwin, Neal; Ishikawa, Fumihiko; Hosur, Vishnu; Lyons, Bonnie L.; Greiner, Dale L.
2014-01-01
Since the discovery of the “nude” mouse over 40 years ago, investigators have attempted to model human tumor growth in immunodeficient mice. The field has advanced significantly over the ensuing years due to improvements in the murine recipient of human tumors. These improvements include the discovery of the scid mutation and development of targeted mutations in the recombination activating genes 1 and 2 (Rag1null, Rag2null) that severely cripple the adaptive immune response of the murine hos...
Leucine supplementation via drinking water reduces atherosclerotic lesions in apoE null mice
Zhao, Yang; Dai, Xiao-Yan; Zhou, Zhou; Zhao, Ge-xin; Wang, Xian; Xu, Ming-Jiang
2015-01-01
Aim: Recent evidence suggests that the essential amino acid leucine may be involved in systemic cholesterol metabolism. In this study, we investigated the effects of leucine supplementation on the development of atherosclerosis in apoE null mice. Methods: ApoE null mice were fed with chow supplemented with leucine (1.5% w/v) in drinking water for 8 week. Aortic atherosclerotic lesions were examined using Oil Red O staining. Plasma lipoprotein-cholesterol levels were measured with fast protein...
First-Order Adaptive Azimuthal Null-Steering for the Suppression of Two Directional Interferers
Derkx RenéMM
2010-01-01
Abstract An azimuth steerable first-order superdirectional microphone response can be constructed by a linear combination of three eigenbeams: a monopole and two orthogonal dipoles. Although the response of a (rotation symmetric) first-order response can only exhibit a single null, we will look at a slice through this beampattern lying in the azimuthal plane. In this way, we can define maximally two nulls in the azimuthal plane which are symmetric with respect to the main-lobe axis. By placin...
[Development of a new type soybean germplasm with null lipoxygenase isozymes].
Han, Fen-Xia; Ding, An-Lin; Sun, Jun-Ming; Li, Gui-Ying
2005-02-01
Soybean protein is a kind of high-quality protein composed of balanced amino acids. It contains all kinds of amino acids, especially eight amino acids necessary for human, but also contains some components that are not good for human and affect food quality, such as Lipoxygenase (Lox) and Trypsin inhibitor (Ti). Nutritional value and processing quality of soybean can be improved by means of development of new variety with null Lox and Ti. In this paper, a new type soybean germplasm with null lipoxygenase isozymes was developed by Institute of Crop Sciences, Chinese Academy of Agricultural Sciences through years of biochemical marker assistant selection for null lipoxygenase by means of isoelectric focusing-polyacrylamid gel electrophoresis (IEF-PAGE) in the hybrid progenies of "96P17" (Female parent, a null lipoxygenase 2.3 line) and "93704" (Male parent, a null lipoxygenase 1.3 line). It is the first new soybean germplasm with null Lox1.2.3 genes in our country, which will contribute to soybean breeding for high quality, soybean production and utilization. In this paper, the development process of new type soybean germplasm is described. PMID:15759868
Why are flare ribbons associated with the spines of magnetic null points generically elongated?
Pontin, D I; Demoulin, P
2016-01-01
Coronal magnetic null points exist in abundance as demonstrated by extrapolations of the coronal field, and have been inferred to be important for a broad range of energetic events. These null points and their associated separatrix and spine field lines represent discontinuities of the field line mapping, making them preferential locations for reconnection. This field line mapping also exhibits strong gradients adjacent to the separatrix (fan) and spine field lines, that can be analysed using the `squashing factor', $Q$. In this paper we make a detailed analysis of the distribution of $Q$ in the presence of magnetic nulls. While $Q$ is formally infinite on both the spine and fan of the null, the decay of $Q$ away from these structures is shown in general to depend strongly on the null-point structure. For the generic case of a non-radially-symmetric null, $Q$ decays most slowly away from the spine/fan in the direction in which $|{\\bf B}|$ increases most slowly. In particular, this demonstrates that the extend...
Investigation of nulling and subpulse drifting properties of PSR J1727$-$2739
Wen, Z G; Yuan, J P; Yan, W M; Manchester, R N; Yuen, R; Gajjar, V
2016-01-01
Aims. To make a detailed study of the nulling and subpulse drifting in PSR J1727$-$2739 for investigation of its radiation properties. Methods. The observations were carried out on 20 March, 2004 using the Parkes 64-m radio telescope, with a central frequency of 1518 MHz. A total of 5568 single pulses were analysed. Results. This pulsar shows well defined nulls with lengths lasting from 6 to 281 pulses and separated by burst phases ranging from 2 to 133 pulses. We estimate a nulling fraction of around 68\\%. No emission in the average pulse profile integrated over all null pulses is detected with significance above $3\\sigma$. Most transitions from nulls to bursts are within a few pulses, whereas the transitions from bursts to nulls exhibit two patterns of decay: decrease gradually or rapidly. In the burst phase, we find that there are two distinct subpulse drift modes with vertical spacing between the drift bands of $9.7 \\pm 1.6$ and $5.2 \\pm 0.9$ pulse periods, while sometimes there is a third mode with no su...
Proving the achronal averaged null energy condition from the generalized second law
International Nuclear Information System (INIS)
A null line is a complete achronal null geodesic. It is proven that for any quantum fields minimally coupled to semiclassical Einstein gravity, the averaged null energy condition (ANEC) on null lines is a consequence of the generalized second law of thermodynamics for causal horizons. This result is shown to leading order in Planck's constant for perturbations to classical backgrounds satisfying the null energy condition. Auxiliary assumptions include CPT and the existence of a suitable renormalization scheme for the generalized entropy. Although the ANEC can be violated on general geodesics in curved spacetimes, as long as the ANEC holds on null lines there exist theorems showing that semiclassical gravity should satisfy positivity of energy, topological censorship, and should not admit closed timelike curves. It is pointed out that these theorems fail once the linearized graviton field is quantized, because then the renormalized shear-squared term in the Raychaudhuri equation can be negative. A 'shear-inclusive' generalization of the ANEC is proposed to remedy this, and is proven under an additional assumption about perturbations to horizons in classical general relativity.
pyNSMC: A Python Module for Null-Space Monte Carlo Uncertainty Analysis
White, J.; Brakefield, L. K.
2015-12-01
The null-space monte carlo technique is a non-linear uncertainty analyses technique that is well-suited to high-dimensional inverse problems. While the technique is powerful, the existing workflow for completing null-space monte carlo is cumbersome, requiring the use of multiple commandline utilities, several sets of intermediate files and even a text editor. pyNSMC is an open-source python module that automates the workflow of null-space monte carlo uncertainty analyses. The module is fully compatible with the PEST and PEST++ software suites and leverages existing functionality of pyEMU, a python framework for linear-based uncertainty analyses. pyNSMC greatly simplifies the existing workflow for null-space monte carlo by taking advantage of object oriented design facilities in python. The core of pyNSMC is the ensemble class, which draws and stores realized random vectors and also provides functionality for exporting and visualizing results. By relieving users of the tedium associated with file handling and command line utility execution, pyNSMC instead focuses the user on the important steps and assumptions of null-space monte carlo analysis. Furthermore, pyNSMC facilitates learning through flow charts and results visualization, which are available at many points in the algorithm. The ease-of-use of the pyNSMC workflow is compared to the existing workflow for null-space monte carlo for a synthetic groundwater model with hundreds of estimable parameters.
Averaged null energy condition and difference inequalities in quantum field theory
International Nuclear Information System (INIS)
For a large class of quantum states, all local (pointwise) energy conditions widely used in relativity are violated by the renormalized stress-energy tensor of a quantum field. In contrast, certain nonlocal positivity constraints on the quantum stress-energy tensor might hold quite generally, and this possibility has received considerable attention in recent years. In particular, it is now known that the averaged null energy condition, the condition that the null-null component of the stress-energy tensor integrated along a complete null geodesic is non-negative for all states, holds quite generally in a wide class of spacetimes for a minimally coupled scalar field. Apart from the specific class of spacetimes considered (mainly two-dimensional spacetimes and four-dimensional Minkowski space), the most significant restriction on this result is that the null geodesic over which the average is taken must be achronal. Recently, Ford and Roman have explored this restriction in two-dimensional flat spacetime, and discovered that in a flat cylindrical space, although the stress energy tensor itself fails to satisfy the averaged null energy condition (ANEC) along the (nonachronal) null geodesics, when the ''Casimir-vacuum'' contribution is subtracted from the stress-energy the resulting tensor does satisfy the ANEC inequality. Ford and Roman name this class of constraints on the quantum stress-energy tensor ''difference inequalities.'' Here I give a proof of the difference inequality for a minimally coupled massless scalar field in an arbitrary (globally hyperbolic) two-dimensional spacetime, using the same techniques as those we relied on to prove the ANEC in an earlier paper with Wald. I begin with an overview of averaged energy conditions in quantum field theory
Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice.
Directory of Open Access Journals (Sweden)
Gerhard Sengle
2015-06-01
Full Text Available Fibrillins are large extracellular macromolecules that polymerize to form the backbone structure of connective tissue microfibrils. Mutations in the gene for fibrillin-1 cause the Marfan syndrome, while mutations in the gene for fibrillin-2 cause Congenital Contractural Arachnodactyly. Both are autosomal dominant disorders, and both disorders affect musculoskeletal tissues. Here we show that Fbn2 null mice (on a 129/Sv background are born with reduced muscle mass, abnormal muscle histology, and signs of activated BMP signaling in skeletal muscle. A delay in Myosin Heavy Chain 8, a perinatal myosin, was found in Fbn2 null forelimb muscle tissue, consistent with the notion that muscle defects underlie forelimb contractures in these mice. In addition, white fat accumulated in the forelimbs during the early postnatal period. Adult Fbn2 null mice are already known to demonstrate persistent muscle weakness. Here we measured elevated creatine kinase levels in adult Fbn2 null mice, indicating ongoing cycles of muscle injury. On a C57Bl/6 background, Fbn2 null mice showed severe defects in musculature, leading to neonatal death from respiratory failure. These new findings demonstrate that loss of fibrillin-2 results in phenotypes similar to those found in congenital muscular dystrophies and that FBN2 should be considered as a candidate gene for recessive congenital muscular dystrophy. Both in vivo and in vitro evidence associated muscle abnormalities and accumulation of white fat in Fbn2 null mice with abnormally activated BMP signaling. Genetic rescue of reduced muscle mass and accumulation of white fat in Fbn2 null mice was accomplished by deleting a single allele of Bmp7. In contrast to other reports that activated BMP signaling leads to muscle hypertrophy, our findings demonstrate the exquisite sensitivity of BMP signaling to the fibrillin-2 extracellular environment during early postnatal muscle development. New evidence presented here suggests that
Üheksa nulli : null null null null null null null... / Anthony de Kowalsky
Kowalsky, Anthony de
2008-01-01
Lühiarvustus 18.- 20. 07. Põlvamaal Intsikurmu laululaval etendunud vabaõhulavastusele "Üheksa nulliga Eesti". Stsenaariumi on kirjutanud Kadri Pettai, Aapo Ilves, Olavi Ruitlane ja Veiko Märka. Lavastanud Reeda Toots
Current singularities at quasi-separatrix layers and three-dimensional magnetic nulls
Energy Technology Data Exchange (ETDEWEB)
Craig, I. J. D.; Effenberger, Frederic, E-mail: feffen@waikato.ac.nz [Department of Mathematics, University of Waikato, P.B. 3105, Hamilton (New Zealand)
2014-11-10
The open problem of how singular current structures form in line-tied, three-dimensional magnetic fields is addressed. A Lagrangian magneto-frictional relaxation method is employed to model the field evolution toward the final near-singular state. Our starting point is an exact force-free solution of the governing magnetohydrodynamic equations that is sufficiently general to allow for topological features like magnetic nulls to be inside or outside the computational domain, depending on a simple set of parameters. Quasi-separatrix layers (QSLs) are present in these structures and, together with the magnetic nulls, they significantly influence the accumulation of current. It is shown that perturbations affecting the lateral boundaries of the configuration lead not only to collapse around the magnetic null but also to significant QSL currents. Our results show that once a magnetic null is present, the developing currents are always attracted to that specific location and show a much stronger scaling with resolution than the currents that form along the QSL. In particular, the null-point scalings can be consistent with models of 'fast' reconnection. The QSL currents also appear to be unbounded but give rise to weaker singularities, independent of the perturbation amplitude.
Teleparallelism as a universal connection on null hypersurfaces in general relativity
Mazur, P. O.; Sokolowski, L. M.
1986-01-01
It is shown that a close relationship between the inner geometry of a null hypersurface N3 and the Newman-Penrose (NP) (1962, 1963) spin coefficient formalism exists. Projecting the null complex NP tetrad onto N3, two triads of basis vectors in N3 are obtained. The inner geometry of N3 is based on the assumption that these vectors are parallelly transported along the surface; this gives rise to the teleparallel connection as a metric nonsymmetric affine connection. The gauge freedom for the choice of the basis triads is given by the isotropy subgroup of the local Lorentz group leaving invariant the direction of the null generators of N3, and teleparallelism is determined by the equivalence class of the basis triads with respect to the global gauge group. Nine of the twelve NP coefficients are identified as the triad components of the torsion and the second fundamental form of N3. The resulting generalized Gauss-Codazzi equations are identical to nine of the NP equations, i.e., to the half of the Ricci identities. This result gives a geometrical meaning to the entire formalism. Finally a general proof of Penrose's theorem that the shear of the null generators of N3 is the only initial null datum for a gravitational field on N3 is presented.
A Null Space Control of Two Wheels Driven Mobile Manipulator Using Passivity Theory
Shibata, Tsuyoshi; Murakami, Toshiyuki
This paper describes a control strategy of null space motion of a two wheels driven mobile manipulator. Recently, robot is utilized in various industrial fields and it is preferable for the robot manipulator to have multiple degrees of freedom motion. Several studies of kinematics for null space motion have been proposed. However stability analysis of null space motion is not enough. Furthermore, these approaches apply to stable systems, but they do not apply unstable systems. Then, in this research, base of manipulator equips with two wheels driven mobile robot. This robot is called two wheels driven mobile manipulator, which becomes unstable system. In the proposed approach, a control design of null space uses passivity based stabilizing. A proposed controller is decided so that closed-loop system of robot dynamics satisfies passivity. This is passivity based control. Then, control strategy is that stabilizing of the robot system applies to work space observer based approach and null space control while keeping end-effector position. The validity of the proposed approach is verified by simulations and experiments of two wheels driven mobile manipulator.
First-Order Adaptive Azimuthal Null-Steering for the Suppression of Two Directional Interferers
Directory of Open Access Journals (Sweden)
Derkx RenéMM
2010-01-01
Full Text Available Abstract An azimuth steerable first-order superdirectional microphone response can be constructed by a linear combination of three eigenbeams: a monopole and two orthogonal dipoles. Although the response of a (rotation symmetric first-order response can only exhibit a single null, we will look at a slice through this beampattern lying in the azimuthal plane. In this way, we can define maximally two nulls in the azimuthal plane which are symmetric with respect to the main-lobe axis. By placing these two nulls on maximally two directional sources to be rejected and compensating for the drop in level for the desired direction, we can effectively reject these directional sources without attenuating the desired source. We present an adaptive null-steering scheme for adjusting the beampattern so as to obtain this suppression of the two directional interferers automatically. Closed-form expressions for this optimal null-steering are derived, enabling the computation of the azimuthal angles of the interferers. It is shown that the proposed technique has a good directivity index when the angular difference between the desired source and each directional interferer is at least 90 degrees.
First-Order Adaptive Azimuthal Null-Steering for the Suppression of Two Directional Interferers
Derkx, René M. M.
2010-12-01
An azimuth steerable first-order superdirectional microphone response can be constructed by a linear combination of three eigenbeams: a monopole and two orthogonal dipoles. Although the response of a (rotation symmetric) first-order response can only exhibit a single null, we will look at a slice through this beampattern lying in the azimuthal plane. In this way, we can define maximally two nulls in the azimuthal plane which are symmetric with respect to the main-lobe axis. By placing these two nulls on maximally two directional sources to be rejected and compensating for the drop in level for the desired direction, we can effectively reject these directional sources without attenuating the desired source. We present an adaptive null-steering scheme for adjusting the beampattern so as to obtain this suppression of the two directional interferers automatically. Closed-form expressions for this optimal null-steering are derived, enabling the computation of the azimuthal angles of the interferers. It is shown that the proposed technique has a good directivity index when the angular difference between the desired source and each directional interferer is at least 90 degrees.
Cluster Observation of Electrostatic Solitary Waves around Magnetic Null Point in Thin Current Sheet
International Nuclear Information System (INIS)
Electrostatic solitary waves (ESWs) are observed in the vicinity of the magnetic null of the widely studied magnetic reconnection taking place at the near-earth tail when current sheet becomes dramatic thinning during substorm time on 1 October 2001. We use the Imada method for the 2-D reconnection model and study the characteristics of ESWs near the X-line region and the magnetic null points. The result shows that the amplitude of the observed ESWs in the vicinity of X-line region ranges from 0.1 mV/m to 5 mV/m, and the amplitude is larger near the magnetic null points. The generation mechanism and the role of ESWs associated with magnetic reconnection are also discussed. (geophysics, astronomy, and astrophysics)
TPF Planet Detection Testbed: demonstrating deep, stable nulling and planet detection
Martin, Stefan
2005-01-01
The design of a testbed being built at the Jet Propulsion Laboratory is described. Simulatiung a dual chopped Bracewell interferometer, the testbed comprises a four beam star and planet source and nulling beam combiner. Since achieving a stable null is of great concern the testbed has many control systems designed to achieve stability of alignment and optical path difference over long periods of time. Comparisons between the testbed and the flight system are drawn and key performance parameters are discussed. The interaction between designs for phaseplate systems that achromatically invert the electric field of one of each pair of the incoming beams to achieve the null and the choice of fringe tracking schemes is also discussed.
Nulling interferometry: performance comparison between Antarctica and other ground-based sites
Absil, O; Barillot, M; Swain, M R
2007-01-01
Detecting the presence of circumstellar dust around nearby solar-type main sequence stars is an important pre-requisite for the design of future life-finding space missions such as ESA's Darwin or NASA's Terrestrial Planet Finder (TPF). The high Antarctic plateau may provide appropriate conditions to perform such a survey from the ground. We investigate the performance of a nulling interferometer optimised for the detection of exozodiacal discs at Dome C, on the high Antarctic plateau, and compare it to the expected performance of similar instruments at temperate sites. Based on the currently available measurements of the turbulence characteristics at Dome C, we adapt the GENIEsim software (Absil et al. 2006, A&A 448) to simulate the performance of a nulling interferometer on the high Antarctic plateau. To feed a realistic instrumental configuration into the simulator, we propose a conceptual design for ALADDIN, the Antarctic L-band Astrophysics Discovery Demonstrator for Interferometric Nulling. We assum...
Quasi-local mass at the null infinity of the Vaidya spacetime
Chen, Po-Ning; Yau, Shing-Tung
2016-01-01
There are two important statements regarding the Trautman-Bondi mass [1,8,5] at null infinity: one is the positivity [7,6], and the other is the Bondi mass loss formula [1], which are both global in nature. The positivity of the quasi-local mass can potentially lead to a local description at null infinity. This is confirmed for the Vaidya spacetime in this note. We study the Wang-Yau quasi-local mass on surfaces of fixed size at the null infinity of the Vaidya spacetime. The optimal embedding equation is solved explicitly and the quasi-local mass is evaluated in terms of the mass aspect function of the Vaidya spacetime.
Kerr/Fluid Duality and Caustics of Null Geodesics on a Horizon
Fujisawa, Ippei
2015-01-01
An equation for a viscous incompressible fluid on a spheroidal surface which is dual to the perturbation around the near-near horizon extreme Kerr (n-NHEK) black hole is derived. It is also shown that an expansion scalar $\\theta$ of a congruence of null geodesics on the null horizon of the perturbed n-NHEK spacetime, which is dual to a viscous incompressible fluid, is not positive semi-definite, even if initial conditions on the velocity are smooth. Unless initial conditions are elaborated, caustics of null congruence will occur on the horizon in the future. A similar result is obtained for a perturbed Schwarzschild black hole spacetime which is dual to a viscous incompressible fluid on $S^2$. An initial condition that $\\theta$ be positive semi-definite at any point on $S^2$ is a necessary condition for the existence of smooth solutions to incompressible Navier-Stokes equation on $S^2$.
Herbonnet, Ricardo; Kuijken, Konrad
2016-01-01
Current optical imaging surveys for cosmology are covering large areas of sky. To exploit the statistical power of these surveys for weak lensing measurements requires shape measurement methods with subpercent systematic errors. We introduce a new weak lensing shear measurement algorithm, Shear Nulling after PSF Gaussianisation (SNAPG), designed to avoid the noise biases that affect most other methods. SNAPG operates on images that have been convolved with a kernel that renders the Point Spread Function (PSF) a circular Gaussian, and uses weighted second moments of the sources. The response of such second moments to a shear of the pre-seeing galaxy image can be predicted analytically, allowing us to construct a shear nulling scheme that finds the shear parameters for which the observed galaxies are consistent with an unsheared, isotropically oriented population of sources. The inverse of this nulling shear is then an estimate of the gravitational lensing shear. We identify the uncertainty of the estimated cen...
Observation of the lower hybrid waves near the three-dimensional null pair
Institute of Scientific and Technical Information of China (English)
A.; VAIVADS; M.; ANDRE
2009-01-01
Magnetic reconnection is a fundamental process in plasma,which is thought to play important roles both in laboratory and natural plasmas through affecting magnetic topology,heating and accelerating particles. During an event on Oct. 1st,2001,the Cluster tetrahedron circled around the magnetic reconnection region several times,and Xiao et al. first identified the null pair and found that the spectrum of the null-point oscillation shows the maximum power near the lower-hybrid frequency. In this paper we report the observation of electromagnetic and electrostatic wave enhancements near lower hybrid frequency associated with the reconnection process near the null pair. The lower hybrid waves(LHWs) with quasi-perpendicular propagation were identified and also confirmed by the power law of the spectrum of electric and magnetic fields.
Fidler, Fiona; Burgman, Mark A; Cumming, Geoff; Buttrose, Robert; Thomason, Neil
2006-10-01
Over the last decade, criticisms of null-hypothesis significance testing have grown dramatically, and several alternative practices, such as confidence intervals, information theoretic, and Bayesian methods, have been advocated. Have these calls for change had an impact on the statistical reporting practices in conservation biology? In 2000 and 2001, 92% of sampled articles in Conservation Biology and Biological Conservation reported results of null-hypothesis tests. In 2005 this figure dropped to 78%. There were corresponding increases in the use of confidence intervals, information theoretic, and Bayesian techniques. Of those articles reporting null-hypothesis testing--which still easily constitute the majority--very few report statistical power (8%) and many misinterpret statistical nonsignificance as evidence for no effect (63%). Overall, results of our survey show some improvements in statistical practice, but further efforts are clearly required to move the discipline toward improved practices. PMID:17002771
Forge-Hardened TiZr Null-Matrix Alloy for Neutron Scattering under Extreme Conditions
Directory of Open Access Journals (Sweden)
Takuo Okuchi
2015-12-01
Full Text Available For neutron scattering research that is performed under extreme conditions, such as high static pressures, high-strength metals that are transparent to the neutron beam are required. The diffraction of the neutron beam by the metal, which follows Bragg’s law, can be completely removed by alloying two metallic elements that have coherent scattering lengths with opposite signs. An alloy of Ti and Zr, which is known as a TiZr null-matrix alloy, is an ideal combination for such purposes. In this study, we increased the hardness of a TiZr null-matrix alloy via extensive mechanical deformation at high temperatures. We successfully used the resulting product in a high-pressure cell designed for high-static-pressure neutron scattering. This hardened TiZr null-matrix alloy may play a complementary role to normal TiZr alloy in future neutron scattering research under extreme conditions.
The symplectic 2-form for gravity in terms of free null initial data
International Nuclear Information System (INIS)
A hypersurface N formed of two null sheets, or ‘light fronts’, swept out by the future null normal geodesics emerging from a common spacelike 2-disc can serve as a Cauchy surface for a region of spacetime. Already in the 1960s, free (unconstrained) initial data for general relativity were found for such hypersurfaces. Here, an expression is obtained for the symplectic 2-form of vacuum general relativity in terms of such free data. This can be done, even though variations of the geometry do not in general preserve the nullness of the initial hypersurface, because of the diffeomorphism gauge invariance of general relativity. The present expression for the symplectic 2-form has been used previously (Reisenberger 2008 Phys. Rev. Lett. 101 211101) to calculate the Poisson brackets of the free data. (paper)
Phase Retrieval with One or Two Diffraction Patterns by Alternating Projections of the Null Vector
Chen, Pengwen; Liu, Gi-Ren
2015-01-01
Two versions of alternating projection (AP), the parallel alternating projection (PAP) and the serial alternating projection (SAP), are proposed to solve phase retrieval with at most two coded diffraction patterns. The proofs of geometric convergence are given with sharp bounds on the rates of convergence in terms of a spectral gap condition. To compensate for the local nature of convergence, the null vector method is proposed for initialization and proved to produce asymptotically accurate initialization for the Gaussian case. Extensive numerical experiments are performed to show that the null vector method produces more accurate initialization than the spectral vector method and that PAP/SAP converge faster to more accurate solutions than other iterative schemes for non-convex optimization such as the Wirtinger flow. Moreover, SAP converges still faster than PAP. In practice AP and the null vector method together produce globally convergent iterates to the true object.
Energetics of kinetic reconnection in a three-dimensional null points cluster
Olshevsky, Vyacheslav; Markidis, Stefano
2015-01-01
We performed three-dimensional Particle-in-Cell simulations of magnetic reconnection with multiple magnetic null points. Magnetic field energy conversion into kinetic energy was about five times higher than in traditional Harris sheet configuration. More than 85% of initial magnetic field energy was transferred to particle energy during 25 reversed ion cyclofrequencies. Magnetic reconnection in the cluster of null points evolved in three phases. During the first phase, ion beams were excited, that then gave part of their energy back to magnetic field in the second phase. In the third phase, magnetic reconnection occurs in many small patches around the current channels formed along the stripes of low magnetic field. Magnetic reconnection in null points presents essentially three-dimensional features, with no two dimensional symmetries or current sheets.
Analysis of null sets (zero cat ch) made by the Mexican tuna pur se seine fleet (20002013)
Michel J Dreyfus-León; Adán Mejía-Trejo; Juan Carlos Villaseñor-Derbez
2015-01-01
The world tuna fishing fleet is dominated by purse seine boats . Purse seine sets are sometimes unsuccessful in capturing fish ; these unsuccessful attempts are known as null sets. Null sets h ave been widely documented and the numbers indicate that they h appen in large proportions. In Mexico, the tuna fishery represents the second most important fishery by volume and value. The frequency of oc currence of null sets during the period 20002013 wa s analyzed to identify the r egions, perio...
Bucciarelli, M.; D. Pastina; Cristallini, D.; M. Sedehi; Lombardo, P.
2016-01-01
A Multichannel Synthetic Aperture Radar (M-SAR) exploiting an antenna nulling based Electronic Counter-Counter Measures (ECCM) technique shall be able to cancel the effects of noise-like interferences over the collected SAR data. Since SAR systems often work with wide bandwidths to provide high resolution images, ECCM technique must account for the presence of wideband interference signal. In this paper we consider a wideband antenna nulling technique based on space-frequency adaptive nulling...
Balance recovery control for biped robot based on reaction null space method
Institute of Scientific and Technical Information of China (English)
Baoping WANG; Renxi HU; Jinming ZHANG; Chuangfeng HUAI
2009-01-01
A biped walking robot should be able to keep balance even in the presence of disturbing forces.This paper presents a step strategy concept of biped walking robot that is stabilized by using reaction null space method.The called "step strategy" can be modeled by means of the reaction null space method that introduced earlier to tackle dynamic interaction problems of free-floating robots,or moving base robots in general.6-DOF biped robot model simulations are used to confirm the validity.
Organic anion transporting polypeptide 1a1 null mice are sensitive to cholestatic liver injury.
Zhang, Youcai; Csanaky, Iván L; Cheng, Xingguo; Lehman-McKeeman, Lois D; Klaassen, Curtis D
2012-06-01
Organic anion transporting polypeptide 1a1 (Oatp1a1) is predominantly expressed in livers of mice and is thought to transport bile acids (BAs) from blood into liver. Because Oatp1a1 expression is markedly decreased in mice after bile duct ligation (BDL). We hypothesized that Oatp1a1-null mice would be protected against liver injury during BDL-induced cholestasis due largely to reduced hepatic uptake of BAs. To evaluate this hypothesis, BDL surgeries were performed in both male wild-type (WT) and Oatp1a1-null mice. At 24 h after BDL, Oatp1a1-null mice showed higher serum alanine aminotransferase levels and more severe liver injury than WT mice, and all Oatp1a1-null mice died within 4 days after BDL, whereas all WT mice survived. At 24 h after BDL, surprisingly Oatp1a1-null mice had higher total BA concentrations in livers than WT mice, suggesting that loss of Oatp1a1 did not prevent BA accumulation in the liver. In addition, secondary BAs dramatically increased in serum of Oatp1a1-null BDL mice but not in WT BDL mice. Oatp1a1-null BDL mice had similar basolateral BA uptake (Na(+)-taurocholate cotransporting polypeptide and Oatp1b2) and BA-efflux (multidrug resistance-associated protein [Mrp]-3, Mrp4, and organic solute transporter α/β) transporters, as well as BA-synthetic enzyme (Cyp7a1) in livers as WT BDL mice. Hepatic expression of small heterodimer partner Cyp3a11, Cyp4a14, and Nqo1, which are target genes of farnesoid X receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and NF-E2-related factor 2, respectively, were increased in WT BDL mice but not in Oatp1a1-null BDL mice. These results demonstrate that loss of Oatp1a1 function exacerbates cholestatic liver injury in mice and suggest that Oatp1a1 plays a unique role in liver adaptive responses to obstructive cholestasis. PMID:22461449
From GLC to double-null coordinates and illustration with static black holes
Nugier, Fabien
2016-01-01
We present a system of coordinates deriving directly from the so-called Geodesic Light-Cone (GLC) coordinates and made of two null scalars intersecting on a 2-dimensional sphere parameterized by two constant angles along geodesics. These coordinates are shown to be equivalent to the well-known double-null coordinates. As GLC, they present interesting properties for cosmology and astrophysics. We discuss this latter topic for static black holes, showing simple descriptions for the metric or particles and photons trajectories. We also briefly comment on the time of flight of ultra-relativistic particles.
The symplectic 2-form for gravity in terms of free null initial data
Reisenberger, Michael P.
2012-01-01
A hypersurface formed of two null sheets, or "light fronts", swept out by the future null normal geodesics emerging from a common spacelike 2-disk can serve as a Cauchy surface for a region of spacetime. Already in the 1960s free (unconstrained) initial data for general relativity were found for such hypersurfaces. Here an expression is obtained for the symplectic 2-form of vacuum general relativity in terms of such free data. This can be done, even though variations of the geometry do not in...
A Fortran Code for Null Geodesic Solutions in the Lemaitre-Tolman-Bondi Spacetime
Ribeiro, M B
2002-01-01
This paper describes the Fortran 77 code SIMU, version 1.1, designed for numerical simulations of observational relations along the past null geodesic in the Lemaitre-Tolman-Bondi (LTB) spacetime. SIMU aims at finding scale invariant solutions of the average density, but due to its full modularity it can be easily adapted to any application which requires LTB's null geodesic solutions. In version 1.1 the numerical output can be read by the GNUPLOT plotting package to produce a fully graphical output, although other plotting routines can be easily adapted. Details of the code's subroutines are discussed, and an example of its output is shown.
Rao, Shanti R.; Wallacea, J. Kent; Samuele, Rocco; Chakrabarti, Supriya; Cook, Timothy; Hicks, Brian; Jung, Paul; Lane, Benjamin; Levine, B. Martin; Mendillo, Chris; Schmidtlin, Edouard; Shao, Mike; Stewart, Jason B.
2008-01-01
We report progress on a nulling coronagraph intended for direct imaging of extrasolar planets. White light is suppressed in an interferometer, and phase errors are measured by a second interferometer. A 1020-pixel MEMS deformable mirror in the first interferometer adjusts the path length across the pupil. A feedback control system reduces deflections of the deformable mirror to order of 1 nm rms.
Quasi-local energy-momentum and energy flux at null infinity
Wu, Xiaoning; Chen, Chiang-Mei; Nester, James M.
2005-01-01
The null infinity limit of the gravitational energy-momentum and energy flux determined by the covariant Hamiltonian quasi-local expressions is evaluated using the NP spin coefficients. The reference contribution is considered by three different embedding approaches. All of them give the expected Bondi energy and energy flux.
The frequency of GSTT1 null genotype in Turkish population and lung cancer risk
Directory of Open Access Journals (Sweden)
Demir A
2005-01-01
Full Text Available BACKGROUND : Previous studies have suggested that Glutathione S -transferase (GST genotypes may play a role in determining susceptibility to lung cancer, though the data are often conflicting. In different ethnic groups variations in null allele frequency has been observed. AIMS: We aimed to evaluate whether genetic polymorphisms of Glutathione S -transferase theta (GSTT1 influence individual susceptibility to lung cancer in Turkish population. We tried to clarify the frequencies of GSTM1 gene polymorphisms in a Turkish population. METHODS: DNA samples, extracted from the whole blood were amplified using polymerase chain reaction (PCR method in all of the 68 cases, composed of 31 previously diagnosed lung cancer and 37 healthy controls. RESULTS: The prevalence of GSTT1 null genotype in the lung cancer patients was 29%, compared to 11% in control group. GSTT1 null genotype was found to be higher in cancer group compared to the control group, although it was not statistically significant (OR = 3.37, 95% CI = 0.92-12.32, P = 0.06. There was also no significant relation in GSTT1 genotypes among histopathology types of lung cancers. The frequency of GSTT1 was found to be 25.4% ( n = 952 when the studies of Turkish population were reviewed. CONCLUSION: It can be concluded that carrying the GSTT1 null genotype may be accepted as a weak risk factor for the susceptibility to lung cancer.
Determination of the true null electrode spacing of an extrapolation chamber for X-ray dosimetry
International Nuclear Information System (INIS)
An accurate determination of the actual null distance is critical for the establishment of primary measurement method for absorbed dose in tissue, since the concept of the true null electrode spacing is used to define the sensitive volume of an extrapolation chamber. In this paper, a critical analysis of two methodologies for determining the true null electrode spacing of an extrapolation chamber was done. Firstly, the ionization current as a function of electrode spacing was measured in ISO 4037 low energy X-ray beams. In the second procedure, a LC Bridge was used to measure the capacitance between the electrodes of a 23392 Böhm model PTW ionization chamber and a reliable relationship between capacitance and relative distance was established. Results showed that the true null spacing values varied from 0.0015 to 0.38 mm. Since capacitance meters with high resolution are not always available in calibration laboratories, the second method showed values with large uncertainties. The first method proved to be highly sensitive to the quality of the X-ray beams used. (author)
Stable deep nulling in polychromatic unpolarized light with multiaxial beam combination.
Buisset, Christophe; Rejeaunier, Xavier; Rabbia, Yves; Barillot, Marc
2007-11-10
In the context of the space-based nulling mission ESA-Darwin, Thales Alenia Space has developed a nulling breadboard for the European Space Agency (ESA): the multiaperture imaging interferometer (MAII) to demonstrate deep and stable nulling and to investigate various subsystems of the ESA-Darwin interferometer. Recently, we have extended our investigations to the multiaxial beam combination. This combination scheme presents many advantages: simplicity, compactness, and a high coupling efficiency for a three-beam combination. The near-infrared (lambda approximately 1.55 microm) MAII breadboard has been upgraded to the multiaxial beam combination. Polarization and stability issues have been thoroughly investigated. We report on the recent results we have obtained with the multiaxial configuration of MAII in unpolarized light with a relative spectral bandwidth of 5%: nulling ratios of mean value N=1.7 x 10(-5), stable over 1 h with a standard deviation sigma( N )=5.7 x 10(-7). These results indicate that the multiaxial beam combination has the potential to meet Darwin requirements. PMID:17994130