PUMA: An Operating System for Massively Parallel Systems

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Stephen R. Wheat

1994-01-01

Full Text Available This article presents an overview of PUMA (Performance-oriented, User-managed Messaging Architecture, a message-passing kernel for massively parallel systems. Message passing in PUMA is based on portals – an opening in the address space of an application process. Once an application process has established a portal, other processes can write values into the portal using a simple send operation. Because messages are written directly into the address space of the receiving process, there is no need to buffer messages in the PUMA kernel and later copy them into the applications address space. PUMA consists of two components: the quintessential kernel (Q-Kernel and the process control thread (PCT. Although the PCT provides management decisions, the Q-Kernel controls access and implements the policies specified by the PCT.

Models of regional habitat quality and connectivity for pumas (Puma concolor) in the southwestern United States.

Science.gov (United States)

Dickson, Brett G; Roemer, Gary W; McRae, Brad H; Rundall, Jill M

2013-01-01

The impact of landscape changes on the quality and connectivity of habitats for multiple wildlife species is of global conservation concern. In the southwestern United States, pumas (Puma concolor) are a well distributed and wide-ranging large carnivore that are sensitive to loss of habitat and to the disruption of pathways that connect their populations. We used an expert-based approach to define and derive variables hypothesized to influence the quality, location, and permeability of habitat for pumas within an area encompassing the entire states of Arizona and New Mexico. Survey results indicated that the presence of woodland and forest cover types, rugged terrain, and canyon bottom and ridgeline topography were expected to be important predictors of both high quality habitat and heightened permeability. As road density, distance to water, or human population density increased, the quality and permeability of habitats were predicted to decline. Using these results, we identified 67 high quality patches across the study area, and applied concepts from electronic circuit theory to estimate regional patterns of connectivity among these patches. Maps of current flow among individual pairs of patches highlighted possible pinch points along two major interstate highways. Current flow summed across all pairs of patches highlighted areas important for keeping the entire network connected, regardless of patch size. Cumulative current flow was highest in Arizona north of the Colorado River and around Grand Canyon National Park, and in the Sky Islands region owing to the many small habitat patches present. Our outputs present a first approximation of habitat quality and connectivity for dispersing pumas in the southwestern United States. Map results can be used to help target finer-scaled analyses in support of planning efforts concerned with the maintenance of puma metapopulation structure, as well as the protection of landscape features that facilitate the dispersal

Models of regional habitat quality and connectivity for pumas (Puma concolor in the southwestern United States.

Directory of Open Access Journals (Sweden)

Brett G Dickson

Full Text Available The impact of landscape changes on the quality and connectivity of habitats for multiple wildlife species is of global conservation concern. In the southwestern United States, pumas (Puma concolor are a well distributed and wide-ranging large carnivore that are sensitive to loss of habitat and to the disruption of pathways that connect their populations. We used an expert-based approach to define and derive variables hypothesized to influence the quality, location, and permeability of habitat for pumas within an area encompassing the entire states of Arizona and New Mexico. Survey results indicated that the presence of woodland and forest cover types, rugged terrain, and canyon bottom and ridgeline topography were expected to be important predictors of both high quality habitat and heightened permeability. As road density, distance to water, or human population density increased, the quality and permeability of habitats were predicted to decline. Using these results, we identified 67 high quality patches across the study area, and applied concepts from electronic circuit theory to estimate regional patterns of connectivity among these patches. Maps of current flow among individual pairs of patches highlighted possible pinch points along two major interstate highways. Current flow summed across all pairs of patches highlighted areas important for keeping the entire network connected, regardless of patch size. Cumulative current flow was highest in Arizona north of the Colorado River and around Grand Canyon National Park, and in the Sky Islands region owing to the many small habitat patches present. Our outputs present a first approximation of habitat quality and connectivity for dispersing pumas in the southwestern United States. Map results can be used to help target finer-scaled analyses in support of planning efforts concerned with the maintenance of puma metapopulation structure, as well as the protection of landscape features that facilitate

Involvement of PUMA in pericyte migration induced by methamphetamine.

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Zhang, Yanhong; Zhang, Yuan; Bai, Ying; Chao, Jie; Hu, Gang; Chen, Xufeng; Yao, Honghong

2017-07-01

Mounting evidence indicates that methamphetamine causes blood-brain barrier damage, with emphasis on endothelial cells. The role of pericytes in methamphetamine-induced BBB damage remains unknown. Our study demonstrated that methamphetamine increased the migration of pericytes from the endothelial basement membrane. However, the detailed mechanisms underlying this process remain poorly understood. Thus, we examined the molecular mechanisms involved in methamphetamine-induced pericyte migration. The results showed that exposure of C3H/10T1/2 cells and HBVPs to methamphetamine increased PUMA expression via activation of the sigma-1 receptor, MAPK and Akt/PI3K pathways. Moreover, methamphetamine treatment resulted in the increased migration of C3H/10T1/2 cells and HBVPs. Knockdown of PUMA in pericytes transduced with PUMA siRNA attenuated the methamphetamine-induced increase in cell migration through attenuation of integrin and tyrosine kinase mechanisms, implicating a role of PUMA in the migration of C3H/10T1/2 cells and HBVPs. This study has demonstrated that methamphetamine-mediated pericytes migration involves PUMA up-regulation. Thus, targeted studies of PUMA could provide insights to facilitate the development of a potential therapeutic approach for alleviation of methamphetamine-induced pericyte migration. Copyright © 2017. Published by Elsevier Inc.

A new panel of SNP markers for the individual identification of North American pumas

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Fitak, Robert R.; Naidu, Ashwin; Thompson, Ron W.; Culver, Melanie

2016-01-01

Pumas Puma concolor are one of the most studied terrestrial carnivores because of their widespread distribution, substantial ecological impacts, and conflicts with humans. Over the past decade, managing pumas has involved extensive efforts including the use of genetic methods. Microsatellites have been the most commonly used genetic markers; however, technical artifacts and little overlap of frequently used loci render large-scale comparison of puma genetic data across studies challenging. Therefore, a panel of genetic markers that can produce consistent genotypes across studies without the need for extensive calibrations is essential for range-wide genetic management of puma populations. Here, we describe the development of PumaPlex, a high-throughput assay to genotype 25 single nucleotide polymorphisms in pumas. We validated PumaPlex in 748 North American pumas Puma concolor couguar, and demonstrated its ability to generate reproducible genotypes and accurately identify individuals. Furthermore, in a test using fecal deoxyribonucleic acid (DNA) samples, we found that PumaPlex produced significantly more genotypes with fewer errors than 12 microsatellite loci, 8 of which are commonly used. Our results demonstrate that PumaPlex is a valuable tool for the genetic monitoring and management of North American puma populations. Given the analytical simplicity, reproducibility, and high-throughput capability of single nucleotide polymorphisms, PumaPlex provides a standard panel of markers that promotes the comparison of genotypes across studies and independent of the genotyping technology used.

Table scraps: inter-trophic food provisioning by pumas.

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Elbroch, L Mark; Wittmer, Heiko U

2012-10-23

Large carnivores perform keystone ecological functions through direct predation, or indirectly, through food subsidies to scavengers or trophic cascades driven by their influence on the distributions of their prey. Pumas (Puma concolor) are an elusive, cryptic species difficult to study and little is known about their inter-trophic-level interactions in natural communities. Using new GPS technology, we discovered that pumas in Patagonia provided 232 ± 31 kg of edible meat/month/100 km(2) to near-threatened Andean condors (Vultur gryphus) and other members of a diverse scavenger community. This is up to 3.1 times the contributions by wolves (Canis lupus) to communities in Yellowstone National Park, USA, and highlights the keystone role large, solitary felids play in natural systems. These findings are more pertinent than ever, for managers increasingly advocate controlling pumas and other large felids to bolster prey populations and mitigate concerns over human and livestock safety, without a full understanding of the potential ecological consequences of their actions.

Harwell hardens Staeubli Puma

International Nuclear Information System (INIS)

Watson, C.J.H.

1992-01-01

The Remote Handling and Robotics Department at Harwell, has argued that it ought to be possible to combine all the advantages of the industrial robot - its off-the-shelf availability, low cost and high reliability - with the specific requirements of the nuclear industry, by subjecting an industrial robot to a programme of ''nuclear engineering''. After a careful evaluation, they selected the Staubli Unimation Puma 760 robot as the first candidate for this programme. Three years, and several Pound 100,000s later, they have launched on the market the world's first Nuclear Engineered Advanced Telerobot, or NEATER, as it is called. The device is manufactured by Staubli Unimation, to the same mechanical and QA standards as a standard PUMA, but with all the non-metallic components replaced by radiation tolerant materials. These were chosen by Harwell, after extensive radiation testing and design work, to ensure that the whole robot can tolerate up to 100 MRads - i.e. the highest radiation dose that a robot is likely to experience in a normal nuclear facility. It is controlled, like a normal PUMA, by a VAL 2 industrial robot controller, but this is ''front-ended'' by the Harwell Telerobotic Controller, a PC-based controller, which takes human commands from mechanical ''Input Device'' and translates these into VAL commands, which can then be interpreted by the VAL 2 controller in the normal way. (Author)

DESPUÉS DE LA MUERTE EN EL MUNDO ANDINO. UNA APROXIMACIÓN ANTROPOLÓGICA

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Rodolfo Sánchez

2015-06-01

Full Text Available Este artículo examina las principales miradas que subsisten sobre la posibilidad de una vida ultraterrena, más allá de la muerte. El autor tiene una posición definida al respecto que, en muchos sentidos, sintoniza con la cosmovisión elaborada por el hombre andino a lo largo de los miles de años comprendidos en su desarrollo cultural. A pesar de la forzada evangelización cristiana soportada del siglo XVI en adelante, una buena parte del discurso andino prehispánico sobre los muertos continúa dando sentido a la existencia humana y al orden social en muchas comunidades quechuas y aimaras de los Andes centrales y meridionales. El hombre andino no está afectado de angustia ante la muerte, y establece, por el contrario, relaciones de reciprocidad con sus ancestros. Por sobre la costumbre de conservación a la espera de un día en que los cuerpos resuciten, los andinos tienen el convencimiento de que los muertos, de cualquier tiempo o espacio, tienen la misma vida que anima al cosmos en su conjunto.

The PUMA test program and data analysis

International Nuclear Information System (INIS)

Han, J.T.; Morrison, D.L.

1997-01-01

The PUMA test program is sponsored by the U.S. Nuclear Regulatory Commission to provide data that are relevant to various Boiling Water Reactor phenomena. The author briefly describes the PUMA test program and facility, presents the objective of the program, provides data analysis for a large-break loss-of-coolant accident test, and compares the data with a RELAP5/MOD 3.1.2 calculation

Diet of pumas (Puma concolor) in Sonora, Mexico, as determined by GPS kill sites and molecular identified scat, with comments on jaguar (Panthera onca) diet

Science.gov (United States)

Cassaigne, Ivonne; Medellin, Rodrigo A.; Thompson, Ron W.; Culver, Melanie; Ochoa, Alexander; Vargas, Karla; Childs, Jack L.; Sanderson, Jim; List, Rurik; Torres-Gomez, Armando

2016-01-01

We documented puma (Puma concolor) and jaguar (Panthera onca) prey consumption in northeastern Sonora, Mexico, by investigating global positioning system cluster sites (n = 220), and conducting molecular analyses of scat (n = 116) collected between 2011 and 2013. We used camera trap data (n = 8,976 camera days) to estimate relative abundances of pumas and jaguars. Deer (Odocoileus virginianus) was the most frequent prey for puma found at kill sites (67%) and identified from scat (74%), although based on relative numbers of prey consumed, deer represented 45% and lagomorphs 20% of the proportion of all individuals eaten. A variety of small prey (weighing Sonora.

Veinte años del Régimen Andino de Acceso a Recursos Genéticos

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Mónica Ribadeneira Sarmiento

2017-05-01

Full Text Available El artículo buscar contribuir al conocimiento del régimen legal andino de acceso a recursos genéticos, cuyo instrumento central es la Decisión Andina 391, promulgada en 1996. Se analiza la norma y se presentan sus más evidentes virtudes y limitaciones. Se incluye información sobre la evolución nacional de la decisión en cada uno de los países andinos. El artículo contiene un apartado referido al futuro de la norma en el actual escenario de reingeniería del Sistema Andino de Integración (SAI. Se han consultado documentos, fuentes oficiales, artículos de expertos y entrevistas. El artículo se estructura de la siguiente manera: los orígenes de la norma; el análisis y contenido de la norma andina; el proceso de reglamentación en los países andinos; las virtudes y limitaciones; la coyuntura y el futuro, y, por último, las conclusiones.

LA EVIDENCIALIDAD EN EL CASTELLANO ANDINO NARIÑENSE

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Ómar Andrés Portilla Melo

2010-12-01

Full Text Available Resumen En este texto se hace una descripción de un fenómeno de transferencia semánticopragmática a nivel modal del quechua al castellano andino de la región nariñense. El trabajo está organizado de la siguiente manera: en primer lugar, se introduce el concepto de evidencialidad; después, se hace una breve descripción histórica del quechua y una introducción a su tipología, y, finalmente, se explica la manera en que el contacto lingüístico quechua-español le dio al castellano andino nariñense los aspectos que lo caracterizan. La metodología usada fue la entrevista etnográfica. Como resultado se obtuvo que la influencia del quechua en el castellano del departamento de Nariño no se dio solamente a nivel léxico o sintáctico, sino que alcanzó niveles más profundos.

Jaguar interactions with pumas and prey at the northern edge of jaguars’ range

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Carmina E. Gutiérrez-González

2017-01-01

Full Text Available We present the first study that evaluates jaguar-puma interactions in the arid lands of northern Mexico, where jaguars have their northernmost breeding population and both predators are persecuted for livestock depredation. We tested whether jaguars are the dominant species in this unique ecosystem, where: (1 pumas outnumber jaguars, (2 pumas are better adapted to arid environments, and (3 jaguars and pumas are of similar size. We analyzed four years of data with two approaches; a two species conditional occupancy model and an activity patterns analysis. We used camera location and prey presence as covariates for jaguar and puma detection and presence probabilities. We also explored overlap in activities of predators and prey. Where both species were detected, peccary presence was positively correlated with both jaguar and puma presence, whereas in areas where jaguars were detected but pumas were not, deer presence explained the probability of jaguar presence. We found that both predators were more likely to co-occur together than to be found independently, and so we rejected the hypothesis that jaguars were the dominant species in our study area. Predators were mainly nocturnal and their activity patterns overlapped by 60%. Jaguar, as compared with puma, overlapped more with deer and calves; puma overlapped with calves more than with other prey, suggesting a preference. We believe exploring predator relationships at different scales may help elucidate mechanisms that regulate their coexistence.

Budování sportovní značky PUMA

OpenAIRE

Lečková, Veronika

2015-01-01

Title: PUMA branding Objective: The aim of diploma thesis is to get improvement proposal which could be used for further building of PUMA brand. The research will be carried out on two samples of respondents. The first sample will be Generation Y which is defined by Bergh (2012). A second sample of respondents are employees of the company PUMA. Methods: The entire thesis is focused and based on standardized method of the brand personality from J. L. Aaker (1997), adapted by the authors Geuens...

Variability in assays used for detection of lentiviral infection in bobcats (Lynx rufus), pumas (Puma concolor), and ocelots (Leopardus pardalis)

Science.gov (United States)

Franklin, S.P.; Troyer, J.L.; TerWee, J.A.; Lyren, L.M.; Kays, R.W.; Riley, S.P.D.; Boyce, W.M.; Crooks, K.R.; VandeWoude, S.

2007-01-01

Although lentiviruses similar to feline immunodeficiency virus (FIV) are known to infect numerous felid species, the relative utility of assays used for detecting lentiviral infection has not been compared for many of these hosts. We tested bobcats (Lynx rufus), pumas (Felis concolor), and ocelots (Leopardus pardalis) for exposure to lentivirus using five different assays: puma lentivirus (PLV), African lion lentivirus (LLV), and domestic cat FIV-based immunoblots, a commercially available enzyme-linked immunosorbent assay (ELISA) kit, and nested polymerase chain reaction (PCR). Puma lentivirus immunoblots identified more seropositive individuals than the other antibody-detection assays. The commercial ELISA provided a fair ability to recognize seropositive samples when compared with PLV immunoblot for screening bobcats and ocelots, but not pumas. Polymerase chain reaction identified fewer positive samples than PLV immunoblot for all three species. Immunoblot results were equivalent whether the sample tested was serum, plasma, or whole blood. The results from this study and previous investigations suggest that the PLV immunoblot has the greatest ability to detect reactive samples when screening wild felids of North America and is unlikely to produce false positive results. However, the commercial ELISA kit may provide ap adequate alternative for screening of some species and is more easily adapted to field conditions. ?? Wildlife Disease Association 2007.

E2F-1 induces melanoma cell apoptosis via PUMA up-regulation and Bax translocation

International Nuclear Information System (INIS)

Hao, Hongying; Dong, Yanbin; Bowling, Maria T; Gomez-Gutierrez, Jorge G; Zhou, H Sam; McMasters, Kelly M

2007-01-01

PUMA is a pro-apoptotic Bcl-2 family member that has been shown to be involved in apoptosis in many cell types. We sought to ascertain whether induction of PUMA plays a crucial role in E2F-1-induced apoptosis in melanoma cells. PUMA gene and protein expression levels were detected by real-time PCR and Western blot in SK-MEL-2 and HCT116 cell lines after Ad-E2F-1 infection. Activation of the PUMA promoter by E2F-1 overexpression was detected by dual luciferase reporter assay. E2F-1-induced Bax translocation was shown by immunocytochemistry. The induction of caspase-9 activity was measured by caspase-9 colorimetric assay kit. Up-regulation of the PUMA gene and protein by E2F-1 overexpression was detected by real-time PCR and Western blot analysis in the SK-MEL-2 melanoma cell line. In support of this finding, we found six putative E2F-1 binding sites within the PUMA promoter. Subsequent dual luciferase reporter assay showed that E2F-1 expression could increase the PUMA gene promoter activity 9.3 fold in SK-MEL-2 cells. The role of PUMA in E2F-1-induced apoptosis was further investigated in a PUMA knockout cell line. Cell viability assay showed that the HCT116 PUMA-/- cell line was more resistant to Ad-E2F-1-mediated cell death than the HCT116 PUMA+/+ cell line. Moreover, a 2.2-fold induction of the PUMA promoter was also noted in the HCT116 PUMA+/+ colon cancer cell line after Ad-E2F-1 infection. Overexpression of a truncated E2F-1 protein that lacks the transactivation domain failed to up-regulate PUMA promoter, suggesting that PUMA may be a transcriptional target of E2F-1. E2F-1-induced cancer cell apoptosis was accompanied by Bax translocation from the cytosol to mitochondria and the induction of caspase-9 activity, suggesting that E2F-1-induced apoptosis is mediated by PUMA through the cytochrome C/Apaf-1-dependent pathway. Our studies strongly demonstrated that E2F-1 induces melanoma cell apoptosis via PUMA up-regulation and Bax translocation. The signaling

PUMA Version 6 Multiplatform with Facilities to be coupled with other Simulation Models

International Nuclear Information System (INIS)

Grant, Carlos

2013-01-01

PUMA is a code for nuclear reactor calculation used in all nuclear installations in Argentina for simulation of fuel management, power cycles and transient events by means of spatial kinetic diffusion theory in 3D. For the versions used up to now the WINDOWS platform was used with very good results. Nowadays PUMA must work in different operative systems, LINUX among others, and must also have facilities to be coupled with other models. For this reason this new version was reprogrammed in ADA, language oriented to a safe programming and be found in any operative system. In former versions PUMA was executed through macro instructions written in LOGO. For this version it is possible to use also PYTHON, which makes also possible the access in execution time to internal data of PUMA. The use of PYTHON allows a easy way to couple PUMA with other codes. The possibilities of this new version of PUMA are shown by means of examples of input data and process control using PYTHON and LOGO. It is discussed the implementation of this methodology in other codes to be coupled with PUMA for versions run in WINDOWS and LINUX. (author)

La evidencialidad en el castellano andino nariñense

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Portilla Melo Omar Andrés

2010-12-01

Full Text Available En este texto se hace una descripción de un fenómeno de transferencia semánticopragmática a nivel modal del quechua al castellano andino de la región nariñense. El trabajo está organizado de la siguiente manera: en primer lugar, se introduce el concepto de evidencialidad; después, se hace una breve descripción histórica del quechua y una introducción a su tipología, y, finalmente, se explica la manera en que el contacto lingüístico quechua-español le dio al castellano andino nariñense los aspectos que lo caracterizan. La metodología usada fue la entrevista etnográfica. Como resultado se obtuvo que la influencia del quechua en el castellano del departamento de Nariño no se dio solamente a nivel léxico o sintáctico, sino que alcanzó niveles más profundos.

La evidencialidad en el castellano andino nariñense

Directory of Open Access Journals (Sweden)

Ómar Andrés Portilla Melo

2010-01-01

Full Text Available En este texto se hace una descripción de un fenómeno de transferencia semánticopragmática a nivel modal del quechua al castellano andino de la región nariñense. El trabajo está organizado de la siguiente manera: en primer lugar, se introduce el concepto de evidencialidad; después, se hace una breve descripción histórica del quechua y una introducción a su tipología, y, finalmente, se explica la manera en que el contacto lingüístico quechua-español le dio al castellano andino nariñense los aspectos que lo caracterizan. La metodología usada fue la entrevista etnográfica. Como resultado se obtuvo que la influencia del quechua en el castellano del departamento de Nariño no se dio solamente a nivel léxico o sintáctico, sino que alcanzó niveles más profundos.

Explaining reported puma-related behaviors and behavioral intentions among northern Arizona residents

Science.gov (United States)

Mattson, David J.; Ruther, Elizabeth J.

2012-01-01

Management of pumas in the American West is typified by conflict among stakeholders plausibly rooted in life experiences and worldviews. We used a mail questionnaire to assess demographics, nature-views, puma-related life experiences and behaviors, and support for puma-related policies among residents of northern Arizona. Data from the questionnaire (n = 693 respondents) were used to model behaviors and support for policies. Compared to models based on nature-views and life experiences, those based on demographics had virtually no support from the data. The Utilitarian/Dominionistic nature-view had the strongest effect of any variable in six of seven models, and was associated with firearms and opposition to policies that would limit killing pumas. The Humanistic/Moralistic nature-view was positively associated with non-lethal behaviors and policies in five models. Gender had the strongest effect of any demographic variable. Compared to demographics alone, our results suggest that worldviews provide a more meaningful explanation of reported human behaviors and behavioral intentions regarding pumas.

Transcription factor Sox4 is required for PUMA-mediated apoptosis induced by histone deacetylase inhibitor, TSA.

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Jang, Sang-Min; Kang, Eun-Jin; Kim, Jung-Woong; Kim, Chul-Hong; An, Joo-Hee; Choi, Kyung-Hee

2013-08-23

PUMA is a crucial regulator of apoptotic cell death mediated by p53-dependent and p53-independent mechanisms. In many cancer cells, PUMA expression is induced in response to DNA-damaging reagent in a p53-dependent manner. However, few studies have investigated transcription factors that lead to the induction of PUMA expression via p53-independent apoptotic signaling. In this study, we found that the transcription factor Sox4 increased PUMA expression in response to trichostatin A (TSA), a histone deacetylase inhibitor in the p53-null human lung cancer cell line H1299. Ectopic expression of Sox4 led to the induction of PUMA expression at the mRNA and protein levels, and TSA-mediated up-regulation of PUMA transcription was repressed by the knockdown of Sox4. Using luciferase assays and chromatin immunoprecipitation, we also determined that Sox4 recruits p300 on the PUMA promoter region and increases PUMA gene expression in response to TSA treatment. Taken together, these results suggest that Sox4 is required for p53-independent apoptotic cell death mediated by PUMA induction via TSA treatment. Crown Copyright © 2013. Published by Elsevier Inc. All rights reserved.

COMPOSICIÓN, ESTRUCTURA Y PATRÓN ESPACIAL DE UN BOSQUE TUCUMANO-BOLIVIANO EN EL DEPARTAMENTO DE TARIJA (BOLIVIA

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F. Santiago Zenteno-Ruiz

2010-01-01

Full Text Available El bosque tucumano-boliviano, en su sector correspondiente a Bolivia, ha comenzado a ser conocido con mayor detalle en los últimos años. Sin embargo, los estudios realizados han tenido un carácter más cualitativo o se han realizado en superficies pequeñas (0,1 ha; además, la biogeografía de sus zonas más bajas no está del todo clara. Por otro lado, algunos aspectos ecológicos, como los referidos a patrones espaciales de los árboles, no han sido nunca abordados. Nosotros realizamos el estudio de una hectárea de bosque tucumano-boliviano a 700-950 m, y mapeamos todos los árboles y lianas con DAP ¿10 cm a fin de caracterizar cuantitativamente un área representativa de este bosque. El propósito fue conocer su composición, abundancia y estructura. Realizamos el primer estudio de patrones espaciales para este tipo de bosque en Bolivia. Registramos 591 individuos agrupados en 31 familias, 47 géneros y 57 especies. Seis especies fueron las más abundantes: Urera caracasana, Trichilia clausenii, Piper tucumanum, Diatenopteryx sorbifolia, Chrysophyllum gonocarpum y Cupania vernalis. El bosque estudiado puede considerarse parte del bosque tucumano-boliviano más que del Arco Pleistocénico. El área basal total fue de 29.4 m2/ha. La presencia de lianas fue relativamente baja, lo que indica que se trata de un bosque relativamente poco perturbado. Se trata de un lugar diverso. La riqueza específica resultó comparable a la de los bosques secos de Madidi (La Paz, Bolivia, y superior a la del tucumano-boliviano en el lado argentino, y fue estimada en 74 especies de árboles. La diversidad (3,5 índice Shannon-Wiener es tan alta como la de muchos bosques más tropicales, e incluso algunos amazónicos. Encontramos un patrón espacial aleatorio en los individuos de la comunidad, y la mayoría de las especies presentó agregación a alguna escala espacial.

Hábitos alimentarios del Puma concolor (Carnivora: Felidae en el Parque Nacional Natural Puracé, Colombia

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Andrés Hernández-Guzmán

2011-09-01

Full Text Available La dieta de Puma concolor es ampliamente conocida a lo largo de su distribución, sin embargo, en Colombia no se ha realizado ningún estudio sobre sus hábitos alimentarios. Entre 2007-2009, la dieta de puma fue analizada en el Parque-Nacional-Natural-Puracé, sur occidente de los Andes colombianos. Ítems alimenticios de cinco especies presa fueron identificadas en su dieta; el venado conejo (Pudu mephistophiles es la presa más importante. Como herramienta complementaria para la identificación de huesos y pelos contenidos en heces (n=60, se instalaron seis cámarastrampa en lugares estratégicos, para registrar la presencia de pumas y presas potenciales. El descubrimiento de la dependencia de los pumas con el pudú sugiere una única adaptación de los pumas de paramo a la disponibilidad de presas y resalta su importancia como reguladores de las poblaciones presa. Estos resultados contribuyen a incrementar el poco conocimiento sobre la ecología de pumas de los Andes, de sus presas y de las especies en su conjunto en Colombia. Obtener información sobre el grupo de presas de pumas en diferentes ecosistemas, es esencial para entender los requerimientos regionales para su supervivencia y diseñar acciones de conservación que permitan seguir/evaluar las necesidades particulares de áreas protegidas en toda su distribución.Food habits of Puma concolor (Carnivora: Felidae in the Parque Nacional Natural Puracé,Colombia. Neotropical puma (Puma concolor diet is scarcely known, in particular that of mountain dwelling individuals from Northern South America. This is the first study on pumas from the paramo and the first puma diet analysis for Colombia. The puma diet was studied from 2007 to 2009 in the Puracé National Park in the South Colombian Andes. Paramos are unique neotropical high altitude ecosystems which store and regulate water, and are currently threatened by agricultural expansion and climate change. Seven latrines were monitored for

História, arte e política: o muralismo do boliviano Miguel Alandia Pantoja History, art and politics: the muralism of the Bolivian Miguel Alandia Pantoja

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Everaldo de Oliveira Andrade

2006-01-01

Full Text Available Este artigo pretende avaliar em que medida arte e política se expressaram na criação e na ação do artista e militante político boliviano Miguel Alandia Pantoja, ativo participante de momentos centrais da História do seu país como a guerra do Chaco, a revolução de 1952 e a Comuna de La Paz de 1971. As influências do indigenismo andino e do muralismo mexicano parecem ter-se cruzado com as opções políticas de Alandia e com seu engajamento na proposta dos artistas ligados ao Manifesto por Uma Arte Revolucionária e Independente lançado por André Breton, Diego Rivera e Leon Trotski em 1936, permitindo o surgimento de uma obra original, polêmica e marcante para a História latino-americana.This article intends to evaluate how art and politics are expressed both in the creation and in the action of the Bolivian militant politician Miguel Alandia Pantoja, who was an active participant in decisive moments of his country's history, as the Chaco War, the 1952 Revolution and the Commune of La Paz in 1971. The Andean indigenismo and the Mexican muralist influences seemed to have crossed with Alandia political options and with his enrollment at the proposal made by artists related to the Manifesto for a Revolutionary and Independent Art launched by Andre Breton, Diego Rivera and Leon Trotski in 1936, allowing the uprising of an original and controversial artistic creation for Latin American history.

Direct adaptive control of a PUMA 560 industrial robot

Science.gov (United States)

Seraji, Homayoun; Lee, Thomas; Delpech, Michel

1989-01-01

The implementation and experimental validation of a new direct adaptive control scheme on a PUMA 560 industrial robot is described. The testbed facility consists of a Unimation PUMA 560 six-jointed robot and controller, and a DEC MicroVAX II computer which hosts the Robot Control C Library software. The control algorithm is implemented on the MicroVAX which acts as a digital controller for the PUMA robot, and the Unimation controller is effectively bypassed and used merely as an I/O device to interface the MicroVAX to the joint motors. The control algorithm for each robot joint consists of an auxiliary signal generated by a constant-gain Proportional plus Integral plus Derivative (PID) controller, and an adaptive position-velocity (PD) feedback controller with adjustable gains. The adaptive independent joint controllers compensate for the inter-joint couplings and achieve accurate trajectory tracking without the need for the complex dynamic model and parameter values of the robot. Extensive experimental results on PUMA joint control are presented to confirm the feasibility of the proposed scheme, in spite of strong interactions between joint motions. Experimental results validate the capabilities of the proposed control scheme. The control scheme is extremely simple and computationally very fast for concurrent processing with high sampling rates.

Apoptosis-promoted tumorigenesis: γ-irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death

OpenAIRE

Michalak, Ewa M.; Vandenberg, Cassandra J.; Delbridge, Alex R.D.; Wu, Li; Scott, Clare L.; Adams, Jerry M.; Strasser, Andreas

2010-01-01

Although tumor development requires impaired apoptosis, we describe a novel paradigm of apoptosis-dependent tumorigenesis. Because DNA damage triggers apoptosis through p53-mediated induction of BH3-only proteins Puma and Noxa, we explored their roles in γ-radiation-induced thymic lymphomagenesis. Surprisingly, whereas Noxa loss accelerated it, Puma loss ablated tumorigenesis. Tumor suppression by Puma deficiency reflected its protection of leukocytes from γ-irradiation-induced death, because...

Interfacing models of wildlife habitat and human development to predict the future distribution of puma habitat

Science.gov (United States)

Burdett, Christopher L.; Crooks, Kevin R.; Theobald, David M.; Wilson, Kenneth R.; Boydston, Erin E.; Lyren, Lisa A.; Fisher, Robert N.; Vickers, T. Winston; Morrison, Scott A.; Boyce, Walter M.

2010-01-01

The impact of human land uses on ecological systems typically differ relative to how extensively natural conditions are modified. Exurban development is intermediate-intensity residential development that often occurs in natural landscapes. Most species-habitat models do not evaluate the effects of such intermediate levels of human development and even fewer predict how future development patterns might affect the amount and configuration of habitat. We addressed these deficiencies by interfacing a habitat model with a spatially-explicit housing-density model to study the effect of human land uses on the habitat of pumas (Puma concolor) in southern California. We studied the response of pumas to natural and anthropogenic features within their home ranges and how mortality risk varied across a gradient of human development. We also used our housing-density model to estimate past and future housing densities and model the distribution of puma habitat in 1970, 2000, and 2030. The natural landscape for pumas in our study area consisted of riparian areas, oak woodlands, and open, conifer forests embedded in a chaparral matrix. Pumas rarely incorporated suburban or urban development into their home ranges, which is consistent with the hypothesis that the behavioral decisions of individuals can be collectively manifested as population-limiting factors at broader spatial scales. Pumas incorporated rural and exurban development into their home ranges, apparently perceiving these areas as modified, rather than non-habitat. Overall, pumas used exurban areas less than expected and showed a neutral response to rural areas. However, individual pumas that selected for or showed a neutral response to exurban areas had a higher risk of mortality than pumas that selected against exurban habitat. Exurban areas are likely hotspots for puma-human conflict in southern California. Approximately 10% of our study area will transform from exurban, rural, or undeveloped areas to suburban or

Counterpart experimental study of ISP-42 PANDA tests on PUMA facility

International Nuclear Information System (INIS)

Yang, Jun; Choi, Sung-Won; Lim, Jaehyok; Lee, Doo-Yong; Rassame, Somboon; Hibiki, Takashi; Ishii, Mamoru

2013-01-01

Highlights: ► Counterpart tests were performed on two large-scale BWR integral facilities. ► Similarity of post-LOCA system behaviors observed between two tests. ► Passive core and containment cooling systems work as design in both tests. -- Abstract: A counterpart test to the Passive Nachwärmeabfuhr und Druckabbau Test Anlage (Passive Decay Heat Removal and Depressurization Test Facility, PANDA) International Standard Problem (ISP)-42 test was conducted at the Purdue University Multi-Dimensional Integral Test Assembly (PUMA) facility. Aimed to support code validation on a range of light water reactor (LWR) containment issues, the ISP-42 test consists of six sequential phases (Phases A–F) with separately defined initial and boundary conditions, addressing different stages of anticipated accident scenario and system responses. The counterpart test was performed from Phases A to D, which are within the scope of the normal integral tests performed on the PUMA facility. A scaling methodology was developed by using the PANDA facility as prototype and PUMA facility as test model, and an engineering scaling has been applied to the PUMA facility. The counterpart test results indicated that functions of passive safety systems, such as passive containment cooling system (PCCS) start-up, gravity-driven cooling system (GDCS) discharge, PCCS normal operation and overload function were confirmed in both the PANDA and PUMA facilities with qualitative similarities

PUMAS (Practical Uses of Math And Science) - Low Cost, High Impact

Science.gov (United States)

Kahn, R. A.

2004-12-01

PUMAS is an on-line journal, aimed at giving pre-college teachers brief examples showing how math and science topics taught in K-12 classes can be used in interesting settings, including everyday life. The concept is a simple one - (1) ask scientists, engineers, and other content experts to write up their favorite examples of practical uses, (2) ask the authors to key their examples to the National Standards and Benchmarks, so the material is grade-appropriate and useful in the classroom, (3) have each example peer-reviewed by at least one scientist with a relevant background, and at least one teacher at an appropriate grade level, helping keep an emphasis on quality, and (4) disseminate the examples widely and inexpensively through the PUMAS Web Site (http://pumas.jpl.nasa.gov). PUMAS examples may be activities, anecdotes, descriptions of "neat ideas," formal exercises, puzzles, or demonstrations; each one is a gem, written in the voice of its author. The PUMAS site also provides opportunities for feedback on individual examples and on the journal as a whole. As with most scientific journals, the writing, reviewing, and editing efforts are volunteered; they leverage the "community service" offered by so many teachers and scientists. We have streamlined all aspects of the example submission, review, and search processes so participants can contribute at a high level, with a minimum of extraneous effort. The primary PUMAS operating expenses cover Web Site technical maintenance and computer security. The PUMAS site receives several thousand unique queries per week, and publishes an average of about one new example per month. Maintaining a strong user base has been helped by endorsements from such organizations as the NSTA and NCTM. To contributors we offer an avenue for making a real impact on pre-college education with a relatively small time commitment, and the opportunity for peer-reviewed publication. We are always looking for good examples of the Practical Uses

Using Species Distribution Models to Predict Potential Landscape Restoration Effects on Puma Conservation.

Science.gov (United States)

Angelieri, Cintia Camila Silva; Adams-Hosking, Christine; Ferraz, Katia Maria Paschoaletto Micchi de Barros; de Souza, Marcelo Pereira; McAlpine, Clive Alexander

2016-01-01

A mosaic of intact native and human-modified vegetation use can provide important habitat for top predators such as the puma (Puma concolor), avoiding negative effects on other species and ecological processes due to cascade trophic interactions. This study investigates the effects of restoration scenarios on the puma's habitat suitability in the most developed Brazilian region (São Paulo State). Species Distribution Models incorporating restoration scenarios were developed using the species' occurrence information to (1) map habitat suitability of pumas in São Paulo State, Southeast, Brazil; (2) test the relative contribution of environmental variables ecologically relevant to the species habitat suitability and (3) project the predicted habitat suitability to future native vegetation restoration scenarios. The Maximum Entropy algorithm was used (Test AUC of 0.84 ± 0.0228) based on seven environmental non-correlated variables and non-autocorrelated presence-only records (n = 342). The percentage of native vegetation (positive influence), elevation (positive influence) and density of roads (negative influence) were considered the most important environmental variables to the model. Model projections to restoration scenarios reflected the high positive relationship between pumas and native vegetation. These projections identified new high suitability areas for pumas (probability of presence >0.5) in highly deforested regions. High suitability areas were increased from 5.3% to 8.5% of the total State extension when the landscapes were restored for ≥ the minimum native vegetation cover rule (20%) established by the Brazilian Forest Code in private lands. This study highlights the importance of a landscape planning approach to improve the conservation outlook for pumas and other species, including not only the establishment and management of protected areas, but also the habitat restoration on private lands. Importantly, the results may inform environmental

Movimientos Sociales y Democracia. Notas sobre la Crisis del Sindicalismo Boliviano

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Enrique IBAÑEZ ROJO

2009-11-01

Full Text Available RESUMEN: El caso boliviano demuestra el papel decisivo jugado por los movimientos sociales en los procesos de transición denwcrática. Así como ,sus carencias atribuidas a la peculiar "cultura política" del movimiento obrero boliviano. Sin embargo un análisis del contexto de la transición - caótico, vioknto y con fuerte polarización ideológica - exige la consideración de un conjunto de variables estructurales. La multiplicación de la "incertidumbre estructural" favorecid la inhibición de la acción estratégica constructiva de la COB que junto a las disfuncionalidad de su propuesta sindicalista en una sociedad heterogénea, explica la incapacidad de la central para encauzar el proceso en favor de sus intereses. Se sugiere la urgencia de recomponer la mediación política capazde articular la dispersión del campo popular mediante fórmulas adecuadas a la estructura social y a la tradición hiktórica boliviana.ABSTRACT: The bolivian case shows the decisive rol played by social movements in the proceses towards democracy, so as their lacks, due to the peculiar "political culture" in labor movement. Nevertheless a further analysis of the transition environment - caotic, violent and with a high polarization - has to take into account a set of structural variables. So, the multiplication of structural uncertainty favourend the inhibition of the strategic constructive action of COB that added to plus disfuncionality of the union proposals in a heterogeneous society, explain the union uncapability for guiding the process towards its own interests. Its also suggested the urgency of rebuilding the political mediation capable of structuring the dispersed popular sector by means of suittable formulas to the social structure and historic traditions of Bolivia.

Lorena Córdoba (editora. Dos suizos en la selva. Historias del auge cauchero en el Oriente Boliviano

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Stefano Pau

2016-03-01

Full Text Available El libro "Dos suizos en la selva. Historias del auge cauchero en el Oriente Boliviano" presenta, por primera vez traducidos al castellano, los testimonios memoriales de dos trabajadores caucheros originarios de Suiza que permanecieron en la región de la selva boliviana en los años de su juventud, a comienzos del siglo pasado.

Interdependence of Bad and Puma during ionizing-radiation-induced apoptosis.

Science.gov (United States)

Toruno, Cristhian; Carbonneau, Seth; Stewart, Rodney A; Jette, Cicely

2014-01-01

Ionizing radiation (IR)-induced DNA double-strand breaks trigger an extensive cellular signaling response that involves the coordination of hundreds of proteins to regulate DNA repair, cell cycle arrest and apoptotic pathways. The cellular outcome often depends on the level of DNA damage as well as the particular cell type. Proliferating zebrafish embryonic neurons are highly sensitive to IR-induced apoptosis, and both p53 and its transcriptional target puma are essential mediators of the response. The BH3-only protein Puma has previously been reported to activate mitochondrial apoptosis through direct interaction with the pro-apoptotic Bcl-2 family proteins Bax and Bak, thus constituting the role of an "activator" BH3-only protein. This distinguishes it from BH3-only proteins like Bad that are thought to indirectly promote apoptosis through binding to anti-apoptotic Bcl-2 family members, thereby preventing the sequestration of activator BH3-only proteins and allowing them to directly interact with and activate Bax and Bak. We have shown previously that overexpression of the BH3-only protein Bad in zebrafish embryos supports normal embryonic development but greatly sensitizes developing neurons to IR-induced apoptosis. While Bad has previously been shown to play only a minor role in promoting IR-induced apoptosis of T cells in mice, we demonstrate that Bad is essential for robust IR-induced apoptosis in zebrafish embryonic neural tissue. Moreover, we found that both p53 and Puma are required for Bad-mediated radiosensitization in vivo. Our findings show the existence of a hierarchical interdependence between Bad and Puma whereby Bad functions as an essential sensitizer and Puma as an essential activator of IR-induced mitochondrial apoptosis specifically in embryonic neural tissue.

Organic chemistry of cometary dust as derived from PUMA 1 data

Science.gov (United States)

Kissel, J.; Krueger, F. R.

1989-01-01

Onboard the Halley Fly-By spacecrafts Vega 1, Vega 2, and Giotto were the dust impact mass spectrometers PUMA 1, PUMA 2, and PIA respectively. PUMA 1 was the most sensitive instrument among them. From its data the occurrence of masslines greater than 60 Daltons could be shown to be statistically significant. An analysis of these masslines lead to a scenario, which could explain the masslines as fragment ions from larger molecules which characterize the chemical nature of cometary organic matter as: (1) highly unsaturated hydrocarbons; (2) some of them containing oxygen; (3) less containing nitrogen; and (4) a few containing oxygen and nitrogen as heteroatoms. From the properties of the spectrometer, also some physical parameters of the dust particles could be inferred, such as their density and structure.

Energetics and evasion dynamics of large predators and prey: pumas vs. hounds.

Science.gov (United States)

Bryce, Caleb M; Wilmers, Christopher C; Williams, Terrie M

2017-01-01

Quantification of fine-scale movement, performance, and energetics of hunting by large carnivores is critical for understanding the physiological underpinnings of trophic interactions. This is particularly challenging for wide-ranging terrestrial canid and felid predators, which can each affect ecosystem structure through distinct hunting modes. To compare free-ranging pursuit and escape performance from group-hunting and solitary predators in unprecedented detail, we calibrated and deployed accelerometer-GPS collars during predator-prey chase sequences using packs of hound dogs ( Canis lupus familiaris , 26 kg, n  = 4-5 per chase) pursuing simultaneously instrumented solitary pumas ( Puma concolor , 60 kg, n  = 2). We then reconstructed chase paths, speed and turning angle profiles, and energy demands for hounds and pumas to examine performance and physiological constraints associated with cursorial and cryptic hunting modes, respectively. Interaction dynamics revealed how pumas successfully utilized terrain (e.g., fleeing up steep, wooded hillsides) as well as evasive maneuvers (e.g., jumping into trees, running in figure-8 patterns) to increase their escape distance from the overall faster hounds (avg. 2.3× faster). These adaptive strategies were essential to evasion in light of the mean 1.6× higher mass-specific energetic costs of the chase for pumas compared to hounds (mean: 0.76 vs. 1.29 kJ kg -1  min -1 , respectively). On an instantaneous basis, escapes were more costly for pumas, requiring exercise at ≥90% of predicted [Formula: see text] and consuming as much energy per minute as approximately 5 min of active hunting. Our results demonstrate the marked investment of energy for evasion by a large, solitary carnivore and the advantage of dynamic maneuvers to postpone being overtaken by group-hunting canids.

Energetics and evasion dynamics of large predators and prey: pumas vs. hounds

Directory of Open Access Journals (Sweden)

Caleb M. Bryce

2017-08-01

Full Text Available Quantification of fine-scale movement, performance, and energetics of hunting by large carnivores is critical for understanding the physiological underpinnings of trophic interactions. This is particularly challenging for wide-ranging terrestrial canid and felid predators, which can each affect ecosystem structure through distinct hunting modes. To compare free-ranging pursuit and escape performance from group-hunting and solitary predators in unprecedented detail, we calibrated and deployed accelerometer-GPS collars during predator-prey chase sequences using packs of hound dogs (Canis lupus familiaris, 26 kg, n = 4–5 per chase pursuing simultaneously instrumented solitary pumas (Puma concolor, 60 kg, n = 2. We then reconstructed chase paths, speed and turning angle profiles, and energy demands for hounds and pumas to examine performance and physiological constraints associated with cursorial and cryptic hunting modes, respectively. Interaction dynamics revealed how pumas successfully utilized terrain (e.g., fleeing up steep, wooded hillsides as well as evasive maneuvers (e.g., jumping into trees, running in figure-8 patterns to increase their escape distance from the overall faster hounds (avg. 2.3× faster. These adaptive strategies were essential to evasion in light of the mean 1.6× higher mass-specific energetic costs of the chase for pumas compared to hounds (mean: 0.76 vs. 1.29 kJ kg−1 min−1, respectively. On an instantaneous basis, escapes were more costly for pumas, requiring exercise at ≥90% of predicted $\\dot {\\mathrm{V }}{\\mathrm{O}}_{2\\mathrm{MAX}}$ V ̇ O 2 MAX and consuming as much energy per minute as approximately 5 min of active hunting. Our results demonstrate the marked investment of energy for evasion by a large, solitary carnivore and the advantage of dynamic maneuvers to postpone being overtaken by group-hunting canids.

Radiosensitization effect of recombinant adenoviral-mediated PUMA gene on pancreatic carcinoma cells

International Nuclear Information System (INIS)

Zhu Dongming; Zhang Kejun; Li Dechun; Zhu Xuefeng; Yang Yong

2009-01-01

Objective: To study the effect of PUMA gene mediated by recombinant adenovirus vector combined with radiation on the pancreatic carcinoma. Methods: The PANC-1 cells were infected with Ad- PUMA (MOI=10, 50 and 100, respectively) for 48 h. The expression of PUMA mRNA and protein was detected by RT-PCR and Western blot, respectively. PANC-1 cells were divided into 4 groups: control group, transfection group, irradiation group and combined treatment group. The cell growth inhibition rate and apoptotic rate of PANC-1 cells were assessed by MTT assay and flow cytometry. Human pancreatic carcinomas were transplanted subcutaneously in nude mice, which were randomized into 4 groups: control group, transfection group, irradiation group and combined treatment group. Tumor growth rate and apoptotic index at different time points were recorded in 35 days. Results: The expression of PUMA mRNA and protein was increased with the increase of MOI of Ad-PUMA, which was does-dependant (MOI=10, mRNA=0.46± 0.02, protein=0.75± 0.09; MOI=50, mRNA=1.12±0.09, protein=1.01±0.18; MOI=100, mRNA=1.50±0.08, protein= 1.80±0.15; P 3 , (39.5±9.23)mm 3 , (33.6±10.3)mm 3 and (52.0±11.43)mm 3 , respectively, P<0.05]. And the apoptotic index was increased in the same manner (AI=0.43±0.05, 0.29±0.10, 0.24±0.05 and 0.00±0.00, respectively, P<0.05). Conclusions: Recombinant adenoviral-mediated PUMA gene combined with irradiation could increase the cell-killing effect on pancreatic carcinoma. It is better than that of either one kind of therapy. (authors)

The Perception of the PUMA Brand in the Czech Market

OpenAIRE

Martínková, Kateřina

2017-01-01

The ambition of this master thesis is to provide a deeper insight into a marketing strategy of the multinational company PUMA applied in the Czech Republic. Specifically, the thesis includes a survey of customers designed to examine the perception of the PUMA brand in the Czech market within the target group of people from 16 to 26 years old. One of the essential requirements of this thesis is to provide a very important theoretical background of the marketing field, explaining the basic mark...

Marketingový výzkum hodnoty značky Puma

OpenAIRE

Lhota, Filip

2011-01-01

My thesis introduces a problem of value identification concerning the brand Puma in the Czech Republic. The main objective of this thesis is to find out how is Puma perceived by the Czech population as well as how satisfied and familiar is the Czech population with its products. The theoretical part of the thesis will deal with obtaining information and defining terms in field of marketing research, brand value and propagation. The practical part will include data collection and its processin...

Analýza vývoje sportovních značek (Adidas a Puma)

OpenAIRE

Cajzl, Jan

2014-01-01

Title: Analysis of development of sports brands Adidas and Puma Objectives: The main aim of this thesis is to compile, describe and analyze informations about history and development of sports brands Adidas and Puma. Methods: The main informations obout historical development of Adidas and Puma were processed by direct historical method, method of deduction and progressive method. Research through the comparative method was used marginally. Results: The results show the direction in which the...

Expression and clinical significance of ATM and PUMA gene in patients with colorectal cancer.

Science.gov (United States)

Xiong, Hui; Zhang, Jiangnan

2017-12-01

The expression of ataxia-telangiectasia mutated (ATM) and p53 upregulated modulator of apoptosis (PUMA) genes in patients with colorectal cancer were investigated, to explore the correlation between the expression of ATM and PUMA and tumor development, to evaluate the clinical significance of ATM and PUMA in the treatment of colorectal cancer. Quantitative real-time PCR was used to detect the expression of ATM and PUMA in tumor tissue and adjacent healthy tissue of 67 patients with colorectal cancer and in normal colorectal tissue of 33 patients with colorectal polyps at mRNA level. The expression level of ATM mRNA in colorectal cancer tissues was significantly higher than that in normal mucosa tissues and adjacent non-cancerous tissue (P≤0.05), while no significant differences in expression level of ATM mRNA were found between normal mucosa tissues and adjacent noncancerous tissue (P=0.07). There was a negative correlation between the expression of ATM mRNA and the degree of differentiation of colorectal cancer (r= -0.312, P=0.013), while expression level of ATM mRNA was not significantly correlated with the age, sex, tumor invasion, lymph node metastasis or clinical stage (P>0.05). Expression levels of PUMA mRNA in colorectal cancer tissues, adjacent noncancerous tissue and normal tissues were 0.68±0.07, 0.88±0.04 and 1.76±0.06, respectively. Expression level of PUMA mRNA in colorectal cancer tissues and adjacent noncancerous tissue was significantly lower than that in normal colorectal tissues (PATM mRNA is expressed abnormally in colorectal cancer tissues. Expression of PUMA gene in colorectal carcinoma is downregulated, and is negatively correlated with the occurrence of cancer.

A New Tool for CME Arrival Time Prediction using Machine Learning Algorithms: CAT-PUMA

Science.gov (United States)

Liu, Jiajia; Ye, Yudong; Shen, Chenglong; Wang, Yuming; Erdélyi, Robert

2018-03-01

Coronal mass ejections (CMEs) are arguably the most violent eruptions in the solar system. CMEs can cause severe disturbances in interplanetary space and can even affect human activities in many aspects, causing damage to infrastructure and loss of revenue. Fast and accurate prediction of CME arrival time is vital to minimize the disruption that CMEs may cause when interacting with geospace. In this paper, we propose a new approach for partial-/full halo CME Arrival Time Prediction Using Machine learning Algorithms (CAT-PUMA). Via detailed analysis of the CME features and solar-wind parameters, we build a prediction engine taking advantage of 182 previously observed geo-effective partial-/full halo CMEs and using algorithms of the Support Vector Machine. We demonstrate that CAT-PUMA is accurate and fast. In particular, predictions made after applying CAT-PUMA to a test set unknown to the engine show a mean absolute prediction error of ∼5.9 hr within the CME arrival time, with 54% of the predictions having absolute errors less than 5.9 hr. Comparisons with other models reveal that CAT-PUMA has a more accurate prediction for 77% of the events investigated that can be carried out very quickly, i.e., within minutes of providing the necessary input parameters of a CME. A practical guide containing the CAT-PUMA engine and the source code of two examples are available in the Appendix, allowing the community to perform their own applications for prediction using CAT-PUMA.

Hábitos alimentarios del Puma concolor (Carnivora: Felidae en el Parque Nacional Natural Puracé, Colombia

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Andrés Hernández-Guzmán

2011-09-01

Full Text Available La dieta de Puma concolor es ampliamente conocida a lo largo de su distribución, sin embargo, en Colombia no se ha realizado ningún estudio sobre sus hábitos alimentarios. Entre 2007-2009, la dieta de puma fue analizada en el Parque-Nacional-Natural-Puracé, sur occidente de los Andes colombianos. Ítems alimenticios de cinco especies presa fueron identificadas en su dieta; el venado conejo (Pudu mephistophiles es la presa más importante. Como herramienta complementaria para la identificación de huesos y pelos contenidos en heces (n=60, se instalaron seis cámarastrampa en lugares estratégicos, para registrar la presencia de pumas y presas potenciales. El descubrimiento de la dependencia de los pumas con el pudú sugiere una única adaptación de los pumas de paramo a la disponibilidad de presas y resalta su importancia como reguladores de las poblaciones presa. Estos resultados contribuyen a incrementar el poco conocimiento sobre la ecología de pumas de los Andes, de sus presas y de las especies en su conjunto en Colombia. Obtener información sobre el grupo de presas de pumas en diferentes ecosistemas, es esencial para entender los requerimientos regionales para su supervivencia y diseñar acciones de conservación que permitan seguir/evaluar las necesidades particulares de áreas protegidas en toda su distribución.

Trayectorias, redes migratorias y procesos identitarios, en la conformación del mercado de trabajo agrícola destinado a bolivianos : estudio en dos municipios del este salteño 1960 - 2013.

OpenAIRE

Ataide, Soraya

2015-01-01

La presente tesis pretende aportar a los estudios sobre la segmentación étnica de los mercados laborales en general y de aquellos vinculados a los migrantes bolivianos en Salta (Argentina), en particular. Partimos de la existencia de un mercado de trabajo agrícola segmentado por la pertenencia de los trabajadores al colectivo nacional: bolivianos, en dos municipios de la provincia de Salta, Apolinario Saravia y Gral. Pizarro. En este caso, la migración boliviana conforma un destino temprano, ...

Evaluating public participation exercises - PUMA findings

International Nuclear Information System (INIS)

Vergez, Christian; )

2003-01-01

A programme of work was undertaken under the auspices of the PUMA (Public Management Project) Working Group on Strengthening Government-Citizen Connections during 1999-2000. Two comparative surveys were conducted among 23 OECD member countries and the European Union, and eight in-depth country cases were performed; the results were discussed in five meetings and published as 'OECD PUMA, 2001'. While the benefits of engaging citizens in policy-making may be considerable, governments should not underestimate the risks associated with poorly designed and inadequate measures for information, consultation and active participation. They may seek to inform, consult and encourage active participation by citizens in order to enhance the quality, credibility and legitimacy of their policy decisions. However the opposite effect may be achieved if citizens discover that their efforts to be informed, provide feedback and actively participate are ignored or have no impact at all on the decisions reached. To reduce the risk of rapid disillusionment and further erosion of citizens' trust, governments must ensure that: - information is complete, objective, reliable, relevant, easy to find and understand; - consultation is conducted with clear goals and according to unambiguous rules which clearly state the limits of the exercise and government's obligation to account for the use made of citizens' input; - participation provides sufficient time and flexibility to allow for the emergence of new ideas and proposals on the part of citizens and a mechanism for their integration into government's policy-making process. Yet the comparative study performed by PUMA found that evaluation was often overlooked. There is a striking imbalance between the amount of time, money and energy which OECD Member countries invest in strengthening government-citizen connections and their efforts to evaluate the effectiveness of these measures and their impact on public policy-making

Neoliberalismo socioeconômico e mutações jurídicas do Estado moderno: o Estado Plurinacional boliviano

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Martinho Martins Botelho

2016-02-01

Full Text Available O objetivo do presente artigo é analisar as recentes modificações no ordenamento jurídico constitucional boliviano, no que tange à institucionalização do Estado Plurinacional, criado a partir do diálogo maior entre a democracia cultural, o direito e as instituições econômicas. Em 2009, fora aprovada a Constituição Política do Estado Plurinacional de Bolívia, depois de manifestação por meio de referendo. O legado da nova Constituição Política boliviana reside no desligamento com o antigo regime mais corporativista e voltado para a difusão de um ideal neoliberal socioeconômico.  A compreensão da nova categoria constitucional poderá contribuir para o levantamento de elementos que possibilitem a compreensão de novas mutações constitucionais e intervenções jurídicas na sociedade do século XXI. O presente artigo busca refletir sobre a recente crise do Estado boliviano e na institucionalização do Estado Plurinacional como uma demanda social para a superação das ideias neoliberais.

PUMAS: The On-line journal of Math and Science Examples for Pre-College Education

Science.gov (United States)

Trainer, Melissa G.; Kahn, Ralph A.

2015-11-01

PUMAS - “Practical Uses of Math And Science” - is an on-line collection of brief examples showing how math and science topics taught in K-12 classes can be used in interesting settings, including every day life. The examples are written primarily by scientists, engineers, and other content experts having practical experience with the material. They are aimed mainly at classroom teachers to enrich their presentation of math and science topics. The goal of PUMAS is to capture, for the benefit of pre-college education, the flavor of the vast experience that working scientists have with interesting and practical uses of math and science. There are currently over 80 examples in the PUMAS collection, and they are organized by curriculum topics and tagged with relevant grade levels and curriculum topic benchmarks. The published examples cover a wide range of subject matter: from demonstrating why summer is hot, to describing the fluid dynamics of a lava lamp, to calculating the best age to collect Social Security Benefits. The examples are available to all interested parties via the PUMAS web site: http://pumas.nasa.gov/.We invite the community to participate in the PUMAS collection. We seek scientists and scientific thinkers to provide innovative examples of practical uses for teachers to use to enrich the classroom experience, and content experts to participate in peer-review. We also seek teachers to review examples for originality, accuracy of content, clarity of presentation, and grade-level appropriateness. Finally, we encourage teachers to mine this rich repository for real-world examples to demonstrate the value of math in science in everyday life.

miR-34 increases in vitro PANC-1 cell sensitivity to gemcitabine via targeting Slug/PUMA.

Science.gov (United States)

Zhang, Qing-An; Yang, Xu-Hai; Chen, Dong; Yan, Xiang; Jing, Fu-Chun; Liu, Hong-Qian; Zhang, Ronghua

2018-01-01

miR-34 was deregulated in tumor tissues compared with corresponding noncancerous tissue samples. Furthermore, miR-34 may contribute to cancer-stromal interaction associated with cancer progression. However, whether miR-34 could decrease chemoresistance of cancer cells to chemotherapeutic agent remains unclear. In our study, we examined whether overexpression of miR-34 could sensitize gemcitabine -mediated apoptosis in human pancreatic cancer PANC-1 cells. We found that miR-34 markedly induced gemcitabine -mediated apoptosis in PANC-1 cells. miR-34 induced down-regulation of Slug expression and upregulation of p53 up-regulated modulator of apoptosis (PUMA) expression. The over-expression of Slug or downregulation of PUMA by Slug cDNA or PUMA siRNA transfection markedly blocked miR-34-induced gemcitabine sensitization. Furthermore, miR-34 induced PUMA expression by downregulation of Slug. Taken together, our study demonstrates that miR-34 enhances sensitization against gemcitabine-mediated apoptosis through the down-regulation of Slug expression, and up-regulation of Slug-dependent PUMA expression.

Efectos de la capitalización en el derecho y la economía bolivianos

OpenAIRE

Quintana Orsini, Carlos Raymundo

2005-01-01

Más allá de considerar si la Capitalización fue positiva o negativa, este trabajo pretende mostrar como esta medida de reforma estructural del Estado ha tenido efectos en el derecho y la economía bolivianos. Partiendo de la descripción del modelo de capitalismo de Estado y su crisis a principios de la década de los ochenta, pretendemos mostrar los antecedentes que originaron la adopción de medidas de ajuste estructural en sus diferentes etapas, hasta llegar a las medidas de ...

Las dinámicas de comercialización de la quinua en los países andinos: ¿qué oportunidades y retos para la agricultura familiar campesina?

OpenAIRE

Baudoin, Andrea; Lacroix, Pierril; Bazile, Didier; Chia, Eduardo

2014-01-01

La revalorización de la quinua despierta muchos intereses tanto en los países andinos como europeos y americanos. Este producto andino antes marginado y circunscrito al autoconsumo ha entrado en la dieta de la población urbana de los países andinos y su consumo se difunde en EEUU, Europa y en otras partes del mundo. En los Andes los precios en chacra aumentan y el sector quinuero ha pasado a ser un sector atractivo para las inversiones. De esta chenopodiácea se está comercializando una gran v...

Cholos, incas y fusionistas: El nuevo Perú y la globalización de lo andino

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Annelou Ypeij

2013-04-01

Full Text Available Abstract:   Cholos, incas and fusionistas: The New Peru and the Globalization of 'Lo Andino'This Exploration deals with the cultural changes in Peru from the year 2000. Peru has become a society with more economic, political, social and global opportunities. Within this context, significant cultural changes can be noted. This essay explores cultural expressions such as the weaving associations of the women of Chinchero, the Peruvian cuisine and the rock band Uchpa. All have in common that they reinterpret 'lo andino', or what it is to be Andean, and that they integrate globalized elements. Based on this, a new identity becomes apparent which surpasses the known categories of ethnicity and class.Resumen:Esta exploración trata sobre los cambios culturales en Perú a partir del año 2000. Perú se ha convertido en una sociedad con más oportunidades económicas, políticas, sociales y globales. En este contexto se pueden notar cambios culturales significantes. El ensayo explora expresiones culturales como las asociaciones de tejidos de las mujeres de Chinchero, la gastronomía peruana y la banda de rock Uchpa. Todas tienen en común que reinterpretan lo andino y que integran elementos globalizados. Basándose en ello, surge una nueva identidad que sobrepasa las conocidas categorías de etnicidad y de clase.

p53/PUMA expression in human pulmonary fibroblasts mediates cell activation and migration in silicosis.

Science.gov (United States)

Wang, Wei; Liu, Haijun; Dai, Xiaoniu; Fang, Shencun; Wang, Xingang; Zhang, Yingming; Yao, Honghong; Zhang, Xilong; Chao, Jie

2015-11-18

Phagocytosis of SiO2 into the lung causes an inflammatory cascade that results in fibroblast proliferation and migration, followed by fibrosis. Clinical evidence has indicated that the activation of alveolar macrophages by SiO2 produces rapid and sustained inflammation characterized by the generation of monocyte chemotactic protein 1, which, in turn, induces fibrosis. However, the details of events downstream of monocyte chemotactic protein 1 activity in pulmonary fibroblasts remain unclear. Here, to elucidate the role of p53 in fibrosis induced by silica, both the upstream molecular mechanisms and the functional effects on cell proliferation and migration were investigated. Experiments using primary cultured adult human pulmonary fibroblasts led to the following results: 1) SiO2 treatment resulted in a rapid and sustained increase in p53 and PUMA protein levels; 2) the MAPK and PI3K pathways were involved in the SiO2-induced alteration of p53 and PUMA expression; and 3) RNA interference targeting p53 and PUMA prevented the SiO2-induced increases in fibroblast activation and migration. Our study elucidated a link between SiO2-induced p53/PUMA expression in fibroblasts and cell migration, thereby providing novel insight into the potential use of p53/PUMA in the development of novel therapeutic strategies for silicosis treatment.

CSR och politisk konsumtion : - en studie av Nikes och Pumas CSR- rapporter

OpenAIRE

Björling, Ameli

2010-01-01

“CSR and political consumption – a study of Nike’s and Puma’s CSR-reports” The purpose of this dissertation is to examine if political consumption has influenced multinational corporations to improve their Corporate Social Responsibility reports and policies more, than a company who has not been a target for political consumption. This dissertation is a content analysis of Nike’s and Puma’s first (Nike 2001, Puma 2001) and latest (Nike 2007/09, Puma 2007/08) CSR- reports. Archie Carroll’s mod...

Puma and Trail/Dr5 Pathways Control Radiation-Induced Apoptosis in Distinct Populations of Testicular Progenitors

International Nuclear Information System (INIS)

Coureuil, M.; Tavernier, M.; Barroca, V.; Fouchet, P.; Allemand, I.; Ugolin, N.; Chevillard, S.

2010-01-01

Spermatogonia- stem cells and progenitors of adult spermatogenesis- are killed through a p53-regulated apoptotic process after γ-irradiation but the death effectors are still poorly characterized. Our data demonstrate that both intrinsic and extrinsic apoptotic pathways are involved, and especially that spermatogonia can be split into two main populations, according to apoptotic effectors. Following irradiation both Dr5 and Puma genes are up-regulated in the α 6 -integrin-positive Side Population (SP) fraction, which is highly enriched in spermatogonia. Flow cytometric analysis confirms an increased number of Dr5-expressing SP cells, and Puma-β isoform accumulates in α 6 -integrin positive cellular extracts, enriched in spermatogonia. Trail -/- or Puma -/- spermatogonia display a reduced sensitivity to radiation-induced apoptosis. The TUNEL kinetics strongly suggest that the extrinsic and intrinsic pathways, via Trail/Dr5 and Puma respectively, could be engaged in distinct subpopulations of spermatogonia. Indeed flow cytometric studies show that Dr5 receptor is constitutively present on more than half of the undifferentiated progenitors (Kit - α 6 + SP) and half of the differentiated ones (Kit + α 6 + SP). In addition after irradiation, Puma is not detected in the Dr5-positive cellular fraction isolated by immuno-magnetic purification, while Puma is present in the Dr5-negative cell extracts. In conclusion, adult testicular progenitors are divided into distinct sub-populations by apoptotic effectors, independently of progenitor types (immature Kit-negative versus mature Kit-positive), underscoring differential radiosensitivities characterizing the stem cell/progenitors compartment. (authors)

Geological map of Uruguay Esc 1,100,000. Fuente del Puma Sheet G-27

International Nuclear Information System (INIS)

Preciozzi, F.; Pena, S.

1990-01-01

This work is about the geological map of Uruguay Esc.1.100.000 (Fuente del Puma) and the explanatory memoranda which describes the geological , lithological and sedimentological characteristics soils. The area corresponding to Fuente del Puma is located in the SW of Lavalleja and NW of Maldonado town and its stratigraphy belong to the Cretaceous and Cenozoic formations as well as the Cambrian and upper Precambrian

New light on an old friend: targeting PUMA in radioprotection and therapy of cardiovascular and neurodegenerative diseases.

Science.gov (United States)

Tichy, Ales; Marek, Jan; Havelek, Radim; Pejchal, Jaroslav; Seifrtova, Martina; Zarybnicka, Lenka; Filipova, Alzbeta; Rezacova, Martina; Sinkorova, Zuzana

2018-04-05

This review summarizes recent progress in understanding the role of p53-upregulated mediator of apoptosis (PUMA) in molecular pathways with respect to its potential therapeutic applications. Particular emphasis is given to the PUMA´s role in ionizing radiation-induced signalling as radiotoxicity of normal tissue is mediated mostly via apoptosis. PUMA and its p53-dependent and p53-independent induction is described and potential use as a new target for the development of radioprotective agents is suggested. Further implications, including targeting PUMA to prevent and treat cardiovascular and neurodegenerative diseases, are also discussed together with overview of other therapeutic applications. Finally, basic chemical structures for development of novel PUMA modulators such as pifithrine derivativeses, kinase inhibitors or modulators of Bcl-2 protein family are described. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Lo andino en los murales de Jesús Flores Walpaq

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Mario Leandro Arce De Piero

2018-04-01

Full Text Available En este trabajo exploramos los modos en que lo andino se construye en la producción muralística del artista plástico Jesús Flores Walpq. Nos enfocamos en la definición de rasgos que configuran el centro representacional de lo andino y el proceso de deslizamientos semánticos y retóricos en la enunciación. A medida que el artista fue construyéndose como enunciador autorizado, la construcción del relato en el mural fue variando considerablemente. Si bien no se registran diferencias radicales en el empleo del color, la forma, la línea, etc. sí es significativa la variación en cuanto a la retórica que incorpora al indio en el discurso pictórico. El recorrido parte de la observación de los cambios en la construcción del yo-artista, que parte de la problematización del rol de productor de arte académico hasta plantear rol de “obrero del arte” comprometido con su contexto político, ideológico y artístico. Esto significó para Flores Walpaq adherir a las luchas reivindicatorias por los derechos indígenas. En conjunto, este texto nos lleva a problematizar sobre las condiciones de producción de la pregunta por la identidad en este contexto y las respuestas que los sujetos ensayan y modifican.

Značky Adidas a Puma v letech 2006-08 : komparativní studie

OpenAIRE

Suchá, Helena

2010-01-01

The bachelor thesis "Adidas and Puma brands in the years 2006-2008 : comparative study " deals with comparing the positioning and communication activities of Adidas and Puma sport brands in the years 2006-2008 in both Czech and Global market for sporting goods. Their Sharp origin and history is reflected in the production and marketing communication of brands that belong to the leaders in the sports industry and sponsorships. The first two parts deal with representation of brands Adidas and P...

Vínculos transfronterizos: vida, movilidad y comercio en el barrio boliviano de Iquique, Chile

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Marcela Tapia Ladino

Full Text Available Resumen El estudio del Barrio Boliviano de Iquique permite captar los vínculos laborales e interacciones económicas que dan lugar a prácticas sociales fronterizas y que se expresan en movilidades en el territorio que no siempre implican el establecimiento o sedentarización en el lugar de destino. De modo que el barrio se convierte en un dispositivo comercial fronterizo y en parte de un territorio circulatorio donde las brechas de desarrollo, las diferencias salariales y el efecto llamada del mercado de trabajo explican la circulación de personas por motivos comerciales y laborales más allá de los litigios diplomáticos entre Bolivia y Chile.

El poblamiento en el siglo XVI. Contrastes entre el Caribe y el interior andino

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Marta Herrera Ángel

2007-04-01

Full Text Available Hablar de poblamiento en el Caribe o en el interior andino y, en general, en América en el siglo XVI, desde la perspectiva de la población que lo habitaba, resulta en buena medida un contrasentido, ya que lo que tuvo lugar en la mayor parte de este continente a lo largo del siglo XVI y buena parte del XVII , como consecuencia de la invasión europea. fue un intenso y continuado proceso de despoblamiento. Ese proceso, en todo caso, no significó la desaparición de la población nativa que, por lo menos hasta finales del siglo XVII y comienzos del siglo XVIII, continuó siendo la población mayoritaria en buena parte del territorio. Pero además, es de resaltar que en las llanuras del Caribe colombiano, así como en el interior andino, al igual que en muchas otras partes del territorio americano, el proceso de despoblamiento que tuvo lugar desde finales del siglo XV no fue compensado por el arribo de pobladores de otros continentes.

PUMA Internet Task Logging Using the IDAC-1

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K. N. Tarchanidis

2014-08-01

Full Text Available This project uses an IDAC-1 board to sample the joint angle position of the PUMA 76 1 robot and log the results on a computer. The robot is at the task location and the logging computer is located in a different one. The task the robot is performing is based on a Pseudo Stereo Vision System (PSVS. Internet is the transport media. The protocol used in this project is UDP/IP. The actual angle is taken straight from the PUMA controller. High-resolution potentiometers are connected on each robot joint and are buffered and sampled as potential difference on an A/D converter integrated on the IDAC-1. The logging computer through the Internet acting as client asks for the angle set, the IDAC-1 responds as server with the 10-bit resolution sampling of the joint position. The whole task is logged in a file on the logging computer. This application can give the ability to the Internet user to monitor and log the robot tasks anywhere in the Word Wide Web (www.

Bioética y justicia ambiental en la salud de los pobladores andinos de Perú

Science.gov (United States)

Alcantara Zapata, Diana E.; Mazzei Pimental, Marinella

2018-01-01

Este artículo intenta plasmar el panorama bioético-ambiental de la salud del poblador que habita en la sierra peruana, remarcando la inequidad en el acceso a los servicios de salud que existe en esta región y reflexionando sobre las posibles causas contextuales, históricas y actuales que han originado diferencias entre el poblador andino del incanato y el poblador andino actual, el cambio de cosmovisón sobre el ambiente y los recursos, el deterioro del enfoque de justicia, solidaridad, bienestar y respeto hacia el ser humano y la naturaleza. Además, se describe la salud desde el escenario histórico de esta región, donde la salud pública tiene y tendrá como desafío la aplicación de programas que respondan a las necesidades específicas de esta población, con un enfoque dirigido hacia lo ambiental. PMID:29708219

A Comparative Analysis of Genetic Diversity and Structure in Jaguars (Panthera onca, Pumas (Puma concolor, and Ocelots (Leopardus pardalis in Fragmented Landscapes of a Critical Mesoamerican Linkage Zone.

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Claudia Wultsch

Full Text Available With increasing anthropogenic impact and landscape change, terrestrial carnivore populations are becoming more fragmented. Thus, it is crucial to genetically monitor wild carnivores and quantify changes in genetic diversity and gene flow in response to these threats. This study combined the use of scat detector dogs and molecular scatology to conduct the first genetic study on wild populations of multiple Neotropical felids coexisting across a fragmented landscape in Belize, Central America. We analyzed data from 14 polymorphic microsatellite loci in 1053 scat samples collected from wild jaguars (Panthera onca, pumas (Puma concolor, and ocelots (Leopardus pardalis. We assessed levels of genetic diversity, defined potential genetic clusters, and examined gene flow for the three target species on a countrywide scale using a combination of individual- and population-based analyses. Wild felids in Belize showed moderate levels of genetic variation, with jaguars having the lowest diversity estimates (HE = 0.57 ± 0.02; AR = 3.36 ± 0.09, followed by pumas (HE = 0.57 ± 0.08; AR = 4.20 ± 0.16, and ocelots (HE = 0.63 ± 0.03; AR = 4.16 ± 0.08. We observed low to moderate levels of genetic differentiation for all three target species, with jaguars showing the lowest degree of genetic subdivision across the country, followed by ocelots and pumas. Although levels of genetic diversity and gene flow were still fairly high, we detected evidence of fine-scale genetic subdivision, indicating that levels of genetic connectivity for wild felids in Belize are likely to decrease if habitat loss and fragmentation continue at the current rate. Our study demonstrates the value of understanding fine-scale patterns of gene flow in multiple co-occurring felid species of conservation concern, which is vital for wildlife movement corridor planning and prioritizing future conservation and management efforts within human-impacted landscapes.

Expression of Bim, Noxa, and Puma in non-small cell lung cancer

International Nuclear Information System (INIS)

Sakakibara-Konishi, Jun; Oizumi, Satoshi; Kikuchi, Junko; Kikuchi, Eiki; Mizugaki, Hidenori; Kinoshita, Ichiro; Dosaka-Akita, Hirotoshi; Nishimura, Masaharu

2012-01-01

The BH3-only members of the Bcl-2 protein family have been proposed to play a key role in the control of apoptosis and in the initiation of the apoptotic pathways. In this study, we evaluated the expression of Bim, Noxa, and Puma in non-small cell lung cancer (NSCLC). A total of 135 surgically resected NSCLCs were immunohistochemically assessed for Bim, Noxa, and Puma expression. The immunoscores were determined, and then its correlation with either the clinicopathological variables or the survival outcomes were analyzed. Immunohistochemical reactivity for Bim, Noxa, and Puma was detected in the cytoplasm of the tumor cells. Bim expression was associated with several clinicopathological factors, including sex (p < 0.001), smoking habit (p = 0.03), pathological histology (p = 0.001), pathological T stage (p = 0.03), pathological disease stage (p = 0.02), and differentiation of tumor (p < 0.001). Multivariate logistic regression analysis showed a significant correlation between low Bim expression and squamous cell carcinoma (p = 0.04), in addition to a correlation between high Bim expression and well differentiated tumors (p = 0.02). Analysis of cellular biological expression demonstrated a link between low Bim expression and high Ki67. While Noxa expression was also shown to be correlated with both smoking habit (p = 0.02) and the pathological histology (p = 0.03), there was no strong association observed between the expression and the clinical features when they were examined by a multivariate logistic regression analysis. No correlations were noted between Puma expression and any of the variables. Our analyses also indicated that the expression levels of the BH3-only proteins were not pertinent to the survival outcome. The current analyses demonstrated that Bim expression in the NSCLCs was associated with both squamous cell carcinoma histology and tumor proliferation

Filogeografia de Puma concolor (CARNIVORA, FELIDAE) na América do Sul

OpenAIRE

Eunice Moara Matte

2012-01-01

O felino Puma concolor, também conhecido por puma entre tantos outros nomes, é uma espécie de ampla distribuição no continente americano e está entre as 10 espécies de felídeos existentes na região Neotropical. Sua ampla distribuição e a história geológica das diferentes regiões ocupadas pela espécie ao longo de sua evolução agem diretamente na sua história evolutiva e demográfica. E muito do que aconteceu com a espécie, como expansões ou drásticas reduções demográficas, isolamento geográfico...

Trophic facilitation or limitation? Comparative effects of pumas and black bears on the scavenger community.

Science.gov (United States)

Allen, Maximilian L; Elbroch, L Mark; Wilmers, Christopher C; Wittmer, Heiko U

2014-01-01

Scavenging is a widespread behaviour and an important process influencing food webs and ecological communities. Large carnivores facilitate the movement of energy across trophic levels through the scavenging and decomposition of their killed prey, but competition with large carnivores is also likely to constrain acquisition of carrion by scavengers. We used an experimental approach based on motion-triggered video cameras at black-tailed deer (Odocoileus hemionus columbianus) carcasses to measure the comparative influences of two large carnivores in the facilitation and limitation of carrion acquisition by scavengers. We found that pumas (Puma concolor) and black bears (Ursus americanus) had different effects on their ecological communities. Pumas, as a top-level predator, facilitated the consumption of carrion by scavengers, despite significantly reducing their observed sum feeding times (165.7 min ± 21.2 SE at puma kills 264.3 min ± 30.1 SE at control carcasses). In contrast, black bears, as the dominant scavenger in the system, limited consumption of carrion by scavengers as evidenced by the observed reduction of scavenger species richness recorded at carcasses where they were present (mean = 2.33 ± 0.28 SE), compared to where they were absent (mean = 3.28 ± 0.23 SE). Black bears also had large negative effects on scavenger sum feeding times (88.5 min ± 19.8 SE at carcasses where bears were present, 372.3 min ± 50.0 SE at carcasses where bears were absent). In addition, we found that pumas and black bears both increased the nestedness (a higher level of order among species present) of the scavenger community. Our results suggest that scavengers have species-specific adaptions to exploit carrion despite large carnivores, and that large carnivores influence the structure and composition of scavenger communities. The interactions between large carnivores and scavengers should be considered in future studies of food webs and ecological communities.

Anatomical study of the forearm and hand nerves of the domestic cat ( Felis catus), puma ( Puma concolor) and jaguar ( Panthera onca).

Science.gov (United States)

Sánchez, H L; Silva, L B; Rafasquino, M E; Mateo, A G; Zuccolilli, G O; Portiansky, E L; Alonso, C R

2013-04-01

The innervation of the forearm and hand regions of cats has not been well described despite its importance for any surgery or any neurological disorder. It is probably the main area where disorders of peripheral nerves in this species are observed. In felines, the forelimbs facilitate the jump and represent the most important way for capturing prey. The main muscles and nerves involved in this activity are located in the region of the forearm and hand. The aim of the present study was to provide a detailed description of the innervation of the forearm and hand regions of the jaguar and puma, in comparison with that of the domestic cat, contributing thus with the anatomical knowledge of the area for applying it to surgery and pathology. The forearms of three pumas and two jaguars (all of them fixed in formalin) and of six domestic cats (fresh) were dissected. The nerves path and their forearm distribution patterns of all three species were described. The analysed results indicate that the observed variations between species are minimal; thus, the anatomy described for domestic cats can be widely applied to American wild felids. © 2012 Blackwell Verlag GmbH.

Universitätsbibliografie mit PUMA. Praxisbericht aus der Einführung der Universitätsbibliografie an der Universitätsbibliothek Stuttgart

Directory of Open Access Journals (Sweden)

Sibylle Hermann

2017-12-01

The added value of the Academic Publication Management PUMA at the University of Stuttgart compared to a bibliographic cataloguing environment lies in the direct processing of data by scientists without an interim step via the library. For the university content management system, a plugin is available, which dynamically integrates publication lists into employees’ web pages. The metadata is loaded directly from PUMA, filtered, sorted and can be put out in the citation style desired. PUMA offers many interfaces and display possibilities.

Behavioral response races, predator-prey shell games, ecology of fear, and patch use of pumas and their ungulate prey.

Science.gov (United States)

Laundré, John W

2010-10-01

The predator-prey shell game predicts random movement of prey across the landscape, whereas the behavioral response race and landscape of fear models predict that there should be a negative relationship between the spatial distribution of a predator and its behaviorally active prey. Additionally, prey have imperfect information on the whereabouts of their predator, which the predator should incorporate in its patch use strategy. I used a one-predator-one-prey system, puma (Puma concolor)-mule deer (Odocoileus hemionus) to test the following predictions regarding predator-prey distribution and patch use by the predator. (1) Pumas will spend more time in high prey risk/low prey use habitat types, while deer will spend their time in low-risk habitats. Pumas should (2) select large forage patches more often, (3) remain in large patches longer, and (4) revisit individual large patches more often than individual smaller ones. I tested these predictions with an extensive telemetry data set collected over 16 years in a study area of patchy forested habitat. When active, pumas spent significantly less time in open areas of low intrinsic predation risk than did deer. Pumas used large patches more than expected, revisited individual large patches significantly more often than smaller ones, and stayed significantly longer in larger patches than in smaller ones. The results supported the prediction of a negative relationship in the spatial distribution of a predator and its prey and indicated that the predator is incorporating the prey's imperfect information about its presence. These results indicate a behavioral complexity on the landscape scale that can have far-reaching impacts on predator-prey interactions.

Harnessing the p53-PUMA Axis to Overcome DNA Damage Resistance in Renal Cell Carcinoma

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Xiaoguang Zhou

2014-12-01

Full Text Available Resistance to DNA damage–induced apoptosis is a hallmark of cancer and a major cause of treatment failure and lethal disease outcome. A tumor entity that is largely resistant to DNA-damaging therapies including chemo- or radiotherapy is renal cell carcinoma (RCC. This study was designed to explore the underlying molecular mechanisms of DNA damage resistance in RCC to develop strategies to resensitize tumor cells to DNA damage–induced apoptosis. Here, we show that apoptosis-resistant RCC cells have a disconnect between activation of p53 and upregulation of the downstream proapoptotic protein p53 upregulated modulator of apoptosis (PUMA. We demonstrate that this disconnect is not caused by gene-specific repression through CCCTC-binding factor (CTCF but instead by aberrant chromatin compaction. Treatment with an HDAC inhibitor was found to effectively reactivate PUMA expression on the mRNA and protein level and to revert resistance to DNA damage–induced cell death. Ectopic expression of PUMA was found to resensitize a panel of RCC cell lines to four different DNA-damaging agents tested. Remarkably, all RCC cell lines analyzed were wild-type for p53, and a knockdown was likewise able to sensitize RCC cells to acute genotoxic stress. Taken together, our results indicate that DNA damage resistance in RCC is reversible, involves the p53-PUMA axis, and is potentially targetable to improve the oncological outcomes of RCC patients.

Three pathogens in sympatric populations of pumas, bobcats, and domestic cats: implications for infectious disease transmission.

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Sarah N Bevins

Full Text Available Anthropogenic landscape change can lead to increased opportunities for pathogen transmission between domestic and non-domestic animals. Pumas, bobcats, and domestic cats are sympatric in many areas of North America and share many of the same pathogens, some of which are zoonotic. We analyzed bobcat, puma, and feral domestic cat samples collected from targeted geographic areas. We examined exposure to three pathogens that are taxonomically diverse (bacterial, protozoal, viral, that incorporate multiple transmission strategies (vector-borne, environmental exposure/ingestion, and direct contact, and that vary in species-specificity. Bartonella spp., Feline Immunodeficiency Virus (FIV, and Toxoplasma gondii IgG were detected in all three species with mean respective prevalence as follows: puma 16%, 41% and 75%; bobcat 31%, 22% and 43%; domestic cat 45%, 10% and 1%. Bartonella spp. were highly prevalent among domestic cats in Southern California compared to other cohort groups. Feline Immunodeficiency Virus exposure was primarily associated with species and age, and was not influenced by geographic location. Pumas were more likely to be infected with FIV than bobcats, with domestic cats having the lowest infection rate. Toxoplasma gondii seroprevalence was high in both pumas and bobcats across all sites; in contrast, few domestic cats were seropositive, despite the fact that feral, free ranging domestic cats were targeted in this study. Interestingly, a directly transmitted species-specific disease (FIV was not associated with geographic location, while exposure to indirectly transmitted diseases--vector-borne for Bartonella spp. and ingestion of oocysts via infected prey or environmental exposure for T. gondii--varied significantly by site. Pathogens transmitted by direct contact may be more dependent upon individual behaviors and intra-specific encounters. Future studies will integrate host density, as well as landscape features, to better

Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells

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Liz J. Valente

2016-03-01

Full Text Available Nutlin3a is a small-molecule antagonist of MDM2 that promotes non-genotoxic activation of p53 through p53 protein stabilization and transactivation of p53 target genes. Nutlin3a is the forerunner of a class of cancer therapeutics that have reached clinical trials. Using transgenic and gene-targeted mouse models lacking the critical p53 target genes, p21, Puma, and Noxa, we found that only loss of PUMA conferred profound protection against Nutlin3a-induced killing in both non-transformed lymphoid cells and Eμ-Myc lymphomas in vitro and in vivo. CRISPR/Cas9-mediated targeting of the PUMA gene rendered human hematopoietic cancer cell lines markedly resistant to Nutlin3a-induced cell death. These results demonstrate that PUMA-mediated apoptosis, but not p21-mediated cell-cycle arrest or senescence, is a critical determinant of the therapeutic response to non-genotoxic p53 activation by Nutlin3a. Importantly, in human cancer, PUMA expression may predict patient responses to treatment with MDM2 antagonists.

Anti-cancer effect of novel PAK1 inhibitor via induction of PUMA-mediated cell death and p21-mediated cell cycle arrest.

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Woo, Tae-Gyun; Yoon, Min-Ho; Hong, Shin-Deok; Choi, Jiyun; Ha, Nam-Chul; Sun, Hokeun; Park, Bum-Joon

2017-04-04

Hyper-activation of PAK1 (p21-activated kinase 1) is frequently observed in human cancer and speculated as a target of novel anti-tumor drug. In previous, we also showed that PAK1 is highly activated in the Smad4-deficient condition and suppresses PUMA (p53 upregulated modulator of apoptosis) through direct binding and phosphorylation. On the basis of this result, we have tried to find novel PAK1-PUMA binding inhibitors. Through ELISA-based blind chemical library screening, we isolated single compound, IPP-14 (IPP; Inhibitor of PAK1-PUMA), which selectively blocks the PAK1-PUMA binding and also suppresses cell proliferation via PUMA-dependent manner. Indeed, in PUMA-deficient cells, this chemical did not show anti-proliferating effect. This chemical possessed very strong PAK1 inhibition activity that it suppressed BAD (Bcl-2-asoociated death promoter) phosphorylation and meta-phase arrest via Aurora kinase inactivation in lower concentration than that of previous PAK1 kinase, FRAX486 and AG879. Moreover, our chemical obviously induced p21/WAF1/CIP1 (Cyclin-dependent kinase inhibitor 1A) expression by releasing from Bcl-2 (B-cell lymphoma-2) and by inhibition of AKT-mediated p21 suppression. Considering our result, IPP-14 and its derivatives would be possible candidates for PAK1 and p21 induction targeted anti-cancer drug.

Trophic facilitation or limitation? Comparative effects of pumas and black bears on the scavenger community.

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Maximilian L Allen

Full Text Available Scavenging is a widespread behaviour and an important process influencing food webs and ecological communities. Large carnivores facilitate the movement of energy across trophic levels through the scavenging and decomposition of their killed prey, but competition with large carnivores is also likely to constrain acquisition of carrion by scavengers. We used an experimental approach based on motion-triggered video cameras at black-tailed deer (Odocoileus hemionus columbianus carcasses to measure the comparative influences of two large carnivores in the facilitation and limitation of carrion acquisition by scavengers. We found that pumas (Puma concolor and black bears (Ursus americanus had different effects on their ecological communities. Pumas, as a top-level predator, facilitated the consumption of carrion by scavengers, despite significantly reducing their observed sum feeding times (165.7 min ± 21.2 SE at puma kills 264.3 min ± 30.1 SE at control carcasses. In contrast, black bears, as the dominant scavenger in the system, limited consumption of carrion by scavengers as evidenced by the observed reduction of scavenger species richness recorded at carcasses where they were present (mean = 2.33 ± 0.28 SE, compared to where they were absent (mean = 3.28 ± 0.23 SE. Black bears also had large negative effects on scavenger sum feeding times (88.5 min ± 19.8 SE at carcasses where bears were present, 372.3 min ± 50.0 SE at carcasses where bears were absent. In addition, we found that pumas and black bears both increased the nestedness (a higher level of order among species present of the scavenger community. Our results suggest that scavengers have species-specific adaptions to exploit carrion despite large carnivores, and that large carnivores influence the structure and composition of scavenger communities. The interactions between large carnivores and scavengers should be considered in future studies of food webs and ecological communities.

Inhibition of p38 MAPK enhances ABT-737-induced cell death in melanoma cell lines: novel regulation of PUMA.

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Keuling, Angela M; Andrew, Susan E; Tron, Victor A

2010-06-01

The mitogen-activated protein kinase (MAPK) pathway is constitutively activated in the majority of melanomas, promoting cell survival, proliferation and migration. In addition, anti-apoptotic Bcl-2 family proteins Mcl-1, Bcl-xL and Bcl-2 are frequently overexpressed, contributing to melanoma's well-documented chemoresistance. Recently, it was reported that the combination of MAPK pathway inhibition by specific MEK inhibitors and Bcl-2 family inhibition by BH3-mimetic ABT-737 synergistically induces apoptotic cell death in melanoma cell lines. Here we provide the first evidence that inhibition of another key MAPK, p38, synergistically induces apoptosis in melanoma cells in combination with ABT-737. We also provide novel mechanistic data demonstrating that inhibition of p38 increases expression of pro-apoptotic Bcl-2 protein PUMA. Furthermore, we demonstrate that PUMA can be cleaved by a caspase-dependent mechanism during apoptosis and identify what appears to be the PUMA cleavage product. Thus, our findings suggest that the combination of ABT-737 and inhibition of p38 is a promising, new treatment strategy that acts through a novel PUMA-dependent mechanism.

La dimensión jurídica del derecho comunitario andino

OpenAIRE

Rodero García, Radday

2015-01-01

En ningún lugar se hace tan patente la urgencia de una superación de la tradicional vinculación del Derecho Público al Estado-nación, como en el caso de la región andina. Tanto quienes se dedican a la teoría como a la práctica del Derecho Público en nuestra región son testigos, y frecuentemente actores, del formidable desarrollo del Derecho Público nacido en paralelo a la integración comunitaria andina. Así, este nuevo Derecho público andino aparece como la dimensión jurídico-pública de un es...

mPUMA: a computational approach to microbiota analysis by de novo assembly of operational taxonomic units based on protein-coding barcode sequences.

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Links, Matthew G; Chaban, Bonnie; Hemmingsen, Sean M; Muirhead, Kevin; Hill, Janet E

2013-08-15

Formation of operational taxonomic units (OTU) is a common approach to data aggregation in microbial ecology studies based on amplification and sequencing of individual gene targets. The de novo assembly of OTU sequences has been recently demonstrated as an alternative to widely used clustering methods, providing robust information from experimental data alone, without any reliance on an external reference database. Here we introduce mPUMA (microbial Profiling Using Metagenomic Assembly, http://mpuma.sourceforge.net), a software package for identification and analysis of protein-coding barcode sequence data. It was developed originally for Cpn60 universal target sequences (also known as GroEL or Hsp60). Using an unattended process that is independent of external reference sequences, mPUMA forms OTUs by DNA sequence assembly and is capable of tracking OTU abundance. mPUMA processes microbial profiles both in terms of the direct DNA sequence as well as in the translated amino acid sequence for protein coding barcodes. By forming OTUs and calculating abundance through an assembly approach, mPUMA is capable of generating inputs for several popular microbiota analysis tools. Using SFF data from sequencing of a synthetic community of Cpn60 sequences derived from the human vaginal microbiome, we demonstrate that mPUMA can faithfully reconstruct all expected OTU sequences and produce compositional profiles consistent with actual community structure. mPUMA enables analysis of microbial communities while empowering the discovery of novel organisms through OTU assembly.

Participatory development of incentives to coexist with jaguars and pumas.

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Amit, Ronit; Jacobson, Susan K

2018-01-22

Reducing costs and increasing benefits for rural communities coexisting with large carnivores is necessary for conservation of jaguar (Panthera onca) and puma (Puma concolor). To design acceptable incentives, stakeholders must be involved in the process. We conducted an innovative, structured, group communication process based on a Delphi technique as a template for identifying potential incentives. Community workshops with 133 members of 7 communities and surveys with 25 multidisciplinary experts from government, nongovernmental organizations, and academia provided iterative data to design a plan of incentives through 4 rounds of discussion. The final product integrated 862 ideas into 6 types of incentives: organization of communities, mechanisms for improved dialogue, citizen technical assistance, green labeling for community products, payment for the ecosystem service of biodiversity, and an assessment of financial alternatives. We used quantitative and qualitative techniques to indicate support for decisions about the design of incentives, which reduced researcher subjectivity. The diverse incentives developed and the cooperation from multiple stakeholders resulted in an incentive plan that integrated issues of governance, equity, and social norms. © 2018 Society for Conservation Biology.

High consumption of primates by pumas and ocelots in a remnant of the Brazilian Atlantic Forest

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JL Santos

Full Text Available We studied the diet of the ocelot and puma during the years 2007 and 2008 at the Feliciano Miguel Abdala Reserve, in Minas Gerais, south-eastern Brazil. We collected 49 faecal samples (scats from cats, and identified the species of cat from 23 of them by the analysis of the microstructure patterns of hairs found in their faeces: 17 scats of the puma (Puma concolor and six of the ocelot (Leopardus pardalis. In the puma scats, we identified three species of primates (Brachyteles hypoxanthus, Alouatta guariba and Sapajus nigritus, the remains of which were found in eight of 17 collected (47.1%, representing 26.7% of items consumed. For the ocelot, we detected capuchin monkey (S. nigritus remains in three of the six scats (50%, accounting for 18.7% of items consumed by ocelot. We were unable to identify the cat species in the remaining 26 faecal samples, but we were able to analyse the food items present. Primates were found in five of these 26 faeces (19.2% and represented 10.2% of the items found. Although the sample size is limited, our results indicate a relatively high consumption of primates by felines. We believe that this high predation may be the result of the high local density of primates as well as the greater exposure to the risks of predation in fragmented landscapes, which tends to increase the incidence of the primates using the ground.

Three pathogens in sympatric populations of pumas, bobcats, and domestic cats: Implications for infections disease transmission

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Bevins, Sarah N.; Carver, Scott; Boydston, Erin E.; Lyren, Lisa M.; Alldredge, Mat; Logan, Kenneth A.; Riley, Seth P.D.; Fisher, Robert N.; Vickers, T. Winston; Boyce, Walter; Salman, Mo; Lappin, Michael R.; Crooks, Kevin R.; VandeWoude, Sue

2012-01-01

Anthropogenic landscape change can lead to increased opportunities for pathogen transmission between domestic and non-domestic animals. Pumas, bobcats, and domestic cats are sympatric in many areas of North America and share many of the same pathogens, some of which are zoonotic. We analyzed bobcat, puma, and feral domestic cat samples collected from targeted geographic areas. We examined exposure to three pathogens that are taxonomically diverse (bacterial, protozoal, viral), that incorporate multiple transmission strategies (vector-borne, environmental exposure/ingestion, and direct contact), and that vary in species-specificity. Bartonella spp., Feline Immunodeficiency Virus (FIV), and Toxoplasma gondii IgG were detected in all three species with mean respective prevalence as follows: puma 16%, 41% and 75%; bobcat 31%, 22% and 43%; domestic cat 45%, 10% and 1%. Bartonella spp. were highly prevalent among domestic cats in Southern California compared to other cohort groups. Feline Immunodeficiency Virus exposure was primarily associated with species and age, and was not influenced by geographic location. Pumas were more likely to be infected with FIV than bobcats, with domestic cats having the lowest infection rate. Toxoplasma gondii seroprevalence was high in both pumas and bobcats across all sites; in contrast, few domestic cats were seropositive, despite the fact that feral, free ranging domestic cats were targeted in this study. Interestingly, a directly transmitted species-specific disease (FIV) was not associated with geographic location, while exposure to indirectly transmitted diseases – vector-borne for Bartonella spp. and ingestion of oocysts via infected prey or environmental exposure for T. gondii – varied significantly by site. Pathogens transmitted by direct contact may be more dependent upon individual behaviors and intra-specific encounters. Future studies will integrate host density, as well as landscape features, to better

Plutonium and minor actinides management in thermal high - temperature reactors - the EU FP6 project puma

International Nuclear Information System (INIS)

Kuijper, J. C.

2007-01-01

The High Temperature gas-cooled Reactor (HTR) can fulfil a very useful niche for the purposes of Pu and Minor Actinide (MA) incineration due to its unique and unsurpassed safety features, as well as to the attractive incentives offered by the nature of the coated particle (CP) fuel. No European reactor of this type is currently available, but there has been, and still is, considerable interest internationally. Decisions to construct such a reactor in China and in South Africa have already been made or are about to be made. Apart from the unique and unsurpassed safety features offered by this reactor type, the nature of the CP fuel offers a number of attractive characteristics. In particular, it can withstand burn-ups far beyond that in either LWR or FR systems. Demonstrations as high as 75% FIMA have been achieved. The coated particle itself offers significantly improved proliferation resistance, and finally with a correct choice of the kernel composition, it can be a very effective support for direct geological disposal of the fuel. The overall objective of the PUMA project, a Specific Targeted Research Project (STREP) within the European Union 6th Framework (EU FP6), is to investigate the possibilities for the utilisation and transmutation of plutonium and especially minor actinides in contemporary and future (high temperature) gas-cooled reactor designs, which are promising tools for improving the sustainability of the nuclear fuel cycle. This contributes to the reduction of Pu and MA stockpiles, and also to the development of safe and sustainable reactors for CO 2 -free energy generation. A number of important issues concerning the use of Pu and MA in gas-cooled reactors have already been dealt with in other projects, or are being treated in ongoing projects, e.g. as part of EU FP6. However, further steps are required to demonstrate the potential of HTRs as Pu/MA transmuters based on realistic/feasible designs of CP Pu/MA fuel and the PUMA focuses on necessary

Maximal killing of lymphoma cells by DNA damage–inducing therapy requires not only the p53 targets Puma and Noxa, but also Bim

OpenAIRE

Happo, Lina; Cragg, Mark S.; Phipson, Belinda; Haga, Jon M.; Jansen, Elisa S.; Herold, Marco J.; Dewson, Grant; Michalak, Ewa M.; Vandenberg, Cassandra J.; Smyth, Gordon K.; Strasser, Andreas; Cory, Suzanne; Scott, Clare L.

2010-01-01

DNA-damaging chemotherapy is the backbone of cancer treatment, although it is not clear how such treatments kill tumor cells. In nontransformed lymphoid cells, the combined loss of 2 proapoptotic p53 target genes, Puma and Noxa, induces as much resistance to DNA damage as loss of p53 itself. In Eμ-Myc lymphomas, however, lack of both Puma and Noxa resulted in no greater drug resistance than lack of Puma alone. A third B-cell lymphoma-2 homology domain (BH)3-only gene, Bim, although not a dire...

PUMA and NF-kB Are Cell Signaling Predictors of Reovirus Oncolysis of Breast Cancer.

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Thirukkumaran, Chandini; Shi, Zhong-Qiao; Thirukkumaran, Ponnampalam; Luider, Joanne; Kopciuk, Karen; Spurrell, Jason; Elzinga, Kate; Morris, Don

2017-01-01

Reovirus is a ubiquitous RNA virus that exploits aberrant signaling pathways for its replication. The oncolytic potential of reovirus against numerous cancers under pre-clinical/clinical conditions has been documented by us and others. Despite its proven clinical activity, the underlying mechanisms of reovirus oncolysis is still not well elucidated. If reovirus therapy is to be optimized for cancer, including breast cancer patients, it is imperative to understand the mechanisms of reovirus oncolysis, especially in treatment of resistant tumour. In the present study global gene expression profiling was utilized as a preliminary roadmap to tease-out pivotal molecules involved in reovirus induced apoptosis in breast cancer. Reovirus treated HTB133 and MCF7 breast cancer cells revealed transcriptional alteration of a defined subset of apoptotic genes and members of the nuclear factor-kappa B (NF-kB) family and p53 upregulated modulator of apoptosis (PUMA) were prominent. Since NF-kB can paradoxically suppress or promote apoptosis in cancer, the significance of NF-kB in reovirus oncolysis of breast cancer was investigated. Real time PCR analysis indicated a 2.9-4.3 fold increase in NF-kB p65 message levels following reovirus infection of MCF7 and HTB133, respectively. Nuclear translocation of NF-kB p65 protein was also dramatically augmented post reovirus treatment and correlated with enhanced DNA binding. Pharmacologic inhibition of NF-kB lead to oncolytic protection and significant down regulation of PUMA message levels. PUMA down regulation using siRNA suppressed reovirus oncolysis via significantly repressed apoptosis in p53 mutant HTB133 cells. This study demonstrates for the first time that a prominent pathway of reovirus oncolysis of breast cancer is mediated through NF-kB and that PUMA upregulation is dependent on NF-kB activation. These findings represent potential therapeutic indicators of reovirus treatment in future clinical trials.

COMUNEROS ANDINOS EN LA ADMINISTRACIÓN CHILENA (ARICA, 1880-1929

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ALBERTO DÍAZ ARAYA

2011-05-01

Full Text Available Resumen Se evalúa el impacto generado en los sectores rurales andinos de Arica por la implementación de la estructura y burocracia administrativa chilena post Guerra del Pacífico. A través de registros documentales se hace explícita la participación de comuneros indígenas en la trama estatal chilena en un período de conflicto político y de identidades nacionales. Palabras claves: Comunidad andina – administración chilena – Arica y Tacna. Abstract Assesses the impact generated in the rural Andes Arica for implementing the administrative structure and bureaucracy in Chile after the Pacific War. Through documentary record makes explicit the participation of indigenous community members in the plot Chilean state over a period of political and national identities. Keywords : Andean Community - Chilean government - Arica and Tacna.

LAS ELECCIONES DIRECTAS EN EL PARLAMENTO ANDINO. UN CAMINO PARA FORTALECER SU PAPEL COMO INSTITUCIÓN PROMOTORA DE LA INTEGRACIÓN

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Silvana Insignares Cera

2009-01-01

Full Text Available El Parlamento Andino atraviesa por una serie de inconvenientes que le impiden cumplir su papel como órgano fundamental e institución promotora de la integración andina. A pesar de los intentos plasmados en los tratados constitutivos de la Comunidad, no se ha podido lograr que irradie su identidad legitimadora y fortalezca el carácter democrático fundamental para la evolución del proceso de integración en la Comunidad Andina. Las elecciones directas son una herramienta para que el Parlamento Andino se convierta en un pilar a nivel de las instituciones comunitarias, que permita reforzar el concepto de ciudadanía andina, así como la participación política de los pueblos de los Estados miembros, para que no continúen de espaldas al proceso unificador y se conviertan en pueblo unitario, actor relevante de la comunidad internacional.

Impact of Burnout and Psychosocial Work Characteristics on Future Long-Term Sickness Absence. Prospective Results of the Danish PUMA Study Among Human Service Workers

NARCIS (Netherlands)

Borritz, Marianne; Christensen, Karl Bang; Bultmann, Ute; Rugulies, Reiner; Lund, Thomas; Andersen, Ingelise; Villadsen, Ebbe; Diderichsen, Finn; Kristensen, Tage S.

2010-01-01

Objectives: The objective of this study was to examine if burnout and psychosocial factors predicted long-term sickness absence (>2 weeks) at work unit level. Methods: Data were collected prospectively at 82-work units in human services (PUMA cohort, PUMA: Danish acronym for Burnout, Motivation and

CAT-PUMA: CME Arrival Time Prediction Using Machine learning Algorithms

Science.gov (United States)

Liu, Jiajia; Ye, Yudong; Shen, Chenglong; Wang, Yuming; Erdélyi, Robert

2018-04-01

CAT-PUMA (CME Arrival Time Prediction Using Machine learning Algorithms) quickly and accurately predicts the arrival of Coronal Mass Ejections (CMEs) of CME arrival time. The software was trained via detailed analysis of CME features and solar wind parameters using 182 previously observed geo-effective partial-/full-halo CMEs and uses algorithms of the Support Vector Machine (SVM) to make its predictions, which can be made within minutes of providing the necessary input parameters of a CME.

Rethinking the recent past: Policies of the difference and interculturality

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Fernando Garcés V.

2008-12-01

Full Text Available Desde la década del noventa del siglo pasado se hicieron explícitas unas políticas de la diferencia en los espacios estatales bolivianos (Postero, 2005;Paz, 2005a, 2006.1 Cuando hablamos de políticas de la diferencia nos referimos a la implementación de mecanismos de reconocimiento y tolerancia de la diversidad, cada vez más frecuentes al interior de los Estados del ámbito andino. Estos mecanismos de reconocimiento y tolerancia de la diversidad pueden esconder sutiles mecanismos de dominación bajo un discurso y unas prácticas incorporadoras y asimiladoras de lo diverso en el aparato estatal y en los circuitos de acumulación del capital.2 Se trata de unas políticas que pueden ser encontradas no sólo en declaraciones

«Y VERÁS COMO QUIEREN EN CHILE...»: Un estudio sobre el prejuicio hacia los inmigrantes bolivianos por parte de los jóvenes chilenos

OpenAIRE

Cárdenas C, Manuel

2006-01-01

El objetivo principal de este estudio fue indagar en las formas que toma el prejuicio hacia los inmigrantes de origen boliviano. Hemos utilizado las tipologías que se derivan de las escalas de prejuicio sutil y manifiesto (Pettigrew & Meertens, 1995) para comparar a los sujetos en diferentes variables psicosociales relevantes en la literatura existente sobre prejuicio y racismo. La muestra se compuso de 167 estudiantes de último año de enseñanza media, pertenecientes a diversos centros educac...

Biosynthesized Silver Nanoparticles Used in Preservative Solutions for Chrysanthemum cv. Puma

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Luis M. Carrillo-López

2016-01-01

Full Text Available The use of pulse solutions containing antimicrobials has been reported, but more research is necessary. To increase vase life and to study their effect on opening inflorescences, silver nanoparticles were used in vase solutions for cv. Puma Chrysanthemum stems. The nanoparticles were synthesized biologically using Chenopodium ambrosioides L. applied at concentrations of 0.01, 0.05, 0.1, 0.5, 1, and 5 mM and compared with a control. Treatments were replicated five times. The stems were cut to 50 cm and observed until the end of their vase life. Low concentrations of silver nanoparticles promoted inflorescence opening and leaf yellowing, while the control leaves remained green, but there was a lower degree of inflorescence opening. High concentrations of silver nanoparticles (0.5, 1, and 5 mM caused senescence due to low water uptake through the stems. Statistical differences in inflorescence opening and diameter, bacterial growth (CFU mL−1 in vase solutions, fresh weight, water uptake, and vase life were found among treatments. Longer vase life and less weight loss were observed in the stems exposed to low concentrations of silver nanoparticles. Low concentrations of silver nanoparticles promoted inflorescence opening and increased vase life of Chrysanthemum cv. Puma.

Un abordaje comparativo en torno a la incidencia de la tuberculosis en inmigrantes bolivianos de Buenos Aires y São Paulo

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Alejandro Goldberg

Full Text Available Este trabajo expone de manera exploratoria y desde una perspectiva sociosanitaria regional, en clave comparativa, algunas dimensiones de análisis en torno a la incidencia de la tuberculosis en inmigrantes bolivianos de las ciudades de Buenos Aires y São Paulo. En ambos casos, se trata de un padecimiento ligado a sus modos de vida y de trabajo precarios en talleres textiles clandestinos. Sumado a lo anterior, la falta de documentación en regla, las dificultades de acceso a la atención sanitaria pública y el sufrimiento social experimentado, potencian la situación de vulnerabilidad social de estas personas; aumentando los riesgos de infectarse y desarrollar la enfermedad.

PUMA: a puzzle piece in chloroquine’s antimelanoma activity

Science.gov (United States)

Amaravadi, Ravi K.

2013-01-01

Chloroquine can induce cell death in a subset of cancer cell lines, and some melanoma cell lines are quite susceptible. While it is well known that chloroquine impairs lysosomal function and can serve as an autophagy inhibitor, the molecular target of chloroquine and the subsequent cascade of events that leads to cell death are not fully understood. Recent evidence indicates that in melanoma cell lines, chloroquine induces apoptosis by preventing degradation of the pro-apoptotic BH3-only protein PUMA. This finding adds to the unfolding story of chloroquine’s mechanism of action as a cancer therapeutic agent. PMID:23949767

Globalización, nuevas dinámicas urbanas y estrategias de integración de migrantes andinos indocumentados en Suiza

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Angela Stienen

2003-01-01

integración de migrantes indocumentados. En este estudio de caso sobre migrantes indocumentados de países andinos, se discuten los diferentes patrones de su integración social y económica en Suiza, relacionándolos con la aparición de territorios urbanos contestatarios durante los años 80 y el auge de una nueva clase media urbana durante los 90.

IGF-1 protects against Aβ25-35-induced neuronal cell death via inhibition of PUMA expression and Bax activation.

Science.gov (United States)

Hou, Xunyao; Jin, Yan; Chen, Jian; Hong, Yan; Luo, Dingzhen; Yin, Qingqing; Liu, Xueping

2017-01-10

Amyloid-β-peptide (Aβ) is considered to be the toxic species in AD and causes cell death in the affected areas of patient's brain. Insulin-like growth factor 1 (IGF-1) has been reported to attenuate Aβ toxicity in neuronal cells. However, the molecular mechanisms involved in the neuroprotective function of IGF-1 remain largely unknown. In the present study, we for the first time demonstrated that IGF-1 protects against Aβ-induced neurotoxicity via inhibition of PUMA expression and Bax activation. We found that IGF-1 could activate Akt, which in turn inhibited Aβ-induced FOXO3a nuclear translocation and thus decreased the binding ability of FOXO3a to PUMA promoter, leading to decreased PUMA expression. In addition, IGF-1 inhibited the translocation of Bax to the mitochondria induced by Aβ. Notably, addition of wortmannin, a specific inhibitor of PI3K, significantly abolished the neuroprotective effect of IGF-1, suggesting that IGF-1 exerts its anti-apoptotic effect depend on PI3K activity. Our findings may provide new insights into molecular mechanisms mediated by IGF-1 in cell survival against Aβ-induced apoptosis. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity.

Science.gov (United States)

Litwak, Sara A.; Loh, Kim; Stanley, William J.; Pappas, Evan G.; Wali, Jibran A.; Selck, Claudia; Strasser, Andreas; Thomas, Helen E.; Gurzov, Esteban N.

2016-01-01

BCL-2 proteins have been implicated in the control of glucose homeostasis and metabolism in different cell types. Thus, the aim of this study was to determine the role of the pro-apoptotic BH3-only protein, p53-upregulated-modulator-of-apoptosis (PUMA), in metabolic changes mediated by diet-induced obesity, using PUMA deficient mice. At 10 weeks of age, knockout and wild type mice either continued consuming a low fat chow diet (6% fat), or were fed with a high fat diet (23% fat) for 14–17 weeks. We measured body composition, glucose and insulin tolerance, insulin response in peripheral tissues, energy expenditure, oxygen consumption, and respiratory exchange ratio in vivo. All these parameters were indistinguishable between wild type and knockout mice on chow diet and were modified equally by diet-induced obesity. Interestingly, we observed decreased food intake and ambulatory capacity of PUMA knockout mice on high fat diet. This was associated with increased adipocyte size and fasted leptin concentration in the blood. Our findings suggest that although PUMA is dispensable for glucose homeostasis in lean and obese mice, it can affect leptin levels and food intake during obesity. PMID:27033313

Consumption of an adult Puma yagouaroundi (Felidae by the snake Boa constrictor (Boidae in Central Mexico Consumo de un jaguarundi adulto Puma yagouaroundi (Felidae por la serpiente Boa constrictor (Boidae en el centro de México

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Octavio Monroy-Vilchis

2011-03-01

Full Text Available Few felids have been recorded as being preyed upon by the Boa constrictor snake (Boa constrictor. Documentation of predation on felids by reptiles is scarce, and natural predators of the adult jaguarundi (Puma yagouaroundi are poorly known. Here, we report for the first time an adult male jaguarundi being eaten by the snake Boa constrictor (of 273 cm snout-to-vent length at the Sierra Nanchititla Natural Reserve, Estado de México.Pocos depredadores han sido registrados como presas de la Boa constrictor (Boa constrictor. La depredación de felinos por reptiles es escasamente documentada y los depredadores naturales del jaguarundi (Puma yagouaroundi son pobremente conocidos. Aquí, nosotros informamos de un evento de depredación de un jaguarundi macho adulto que fue consumido por una B. constrictor (longitud hocico-cloaca: 273 cm en la Reserva Natural Sierra Nanchititla, Estado de México.

Portable University Model of the Atmosphere (PUMA)

Energy Technology Data Exchange (ETDEWEB)

Fraedrich, K.; Kirk, E.; Lunkeit, F. [Hamburg Univ. (Germany). Meteorologisches Inst.

1998-10-01

The Portable University Model of the Atmosphere (PUMA) is based on the Reading multi-level spectral model SGCM (Simple Global Circulation Model) described by Hoskins and Simmons (1975) and James and Gray (1986). Originally developed as a numerical prediction model, it was changed to perform as a circulation model. For example, James and Gray (1986) studied the influence of surface friction on the circulation of a baroclinic atmosphere, James and James (1992), and James et al. (1994) investigated ultra-low-frequency variability, and Mole and James (1990) analyzed the baroclinic adjustment in the context of a zonally varying flow. Frisius et al. (1998) simulated an idealized storm track by embedding a dipole structure in a zonally symmetric forcing field and Lunkeit et al. (1998) investigated the sensitivity of GCM (General Circulation Model) scenarios by an adaption technique applicapable to SGCMs. (orig.)

El impacto del TLC frente al derecho comunitario andino

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Marcel Tangarife Torres

2006-01-01

Full Text Available En esta conferencia analiza el impacto del Tratado de Libre Comercio que se celebrará entre la República de Colombia y los Estados Unidos de Norteamérica frente al Derecho Comunitario Andino, con gran importancia en los temas relacionados con la propiedad intelectual. Adicional a lo anterior se suma un aspecto trascendental y es la supervivencia de la Comunidad Andina de Naciones y en este sentido se cuestiona la coexistencia de las normas comunitarias en relación con las previstas en el Tratado de Libre Comercio. De esta manera, se examina el marco constitucional del Tratado de Libre Comercio y del Acuerdo de Cartagena, para así determinar las características que tienen esta clase de tratados y con ello establecer el nivel jerárquico que le corresponden dentro del ordenamiento jurídico Colombiano. Finalmente se observa la prevalencía de las normas del Acuerdo de Cartagena y el Tratado de Libre Comercio o viceversa, para con ello encontrar soluciones frente a los posibles conflictos de normas que se pueden presentar por la coexistencia de dichas normatividades.

Relación del gradiente interior-borde de fragmentos de bosque andino sobre la comunidad de murciélagos en Encino (Santander, Colombia

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Aída Otálora Ardila

2005-01-01

área total y tienen una densidad de 0,39 parches/ha. Los índices calculados revelan que los bosques andinos tienen un menor proceso de fragmentación que los subandinos representado en fragmentos más grandes y más cercanos. El paisaje ha sido muy transformado pues el 90,4% de los fragmentos son

Genetic variability of Herpailurus yagouaroundi, Puma concolor and Panthera onca (Mammalia, Felidae studied using Felis catus microsatellites

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Vanessa Roma Moreno

2006-01-01

Full Text Available We used four microsatellite loci (Fca08, Fca45, Fca77 and Fca96 from the domestic cat, Felis catus, to investigate genetic variability in specimens of Herpailurus yagouaroundi (jaguarundi, otter cat, eyra, Puma concolor (cougar, mountain lion, puma and Panthera onca (jaguar held in various Brazilian zoos. Samples of DNA from the cats were PCR amplified and then sequenced before being analyzed using the CERVUS program. Our results show a mean polymorphic information content (PIC of 0.83 for H. yagouaroundi, 0.66 for P. concolor and 0.69 for P. onca and a mean of 10.3 alleles for the Fca08 locus, 5.3 for Fca 45, 9 for Fca 77 and 14 for Fca 96. These results indicate a relatively high level of genetic diversity for the specimens studied.

Procesos de transformación de los bosques andinos en la microcuenca del río Guacha, Encino, Santander (1978-1994-2006.

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Wilson Fernando Gómez Anaya

2014-01-01

Full Text Available En Colombia, los ecosistemas andinos presentan fuerte intervención demográfica y económica, por consiguiente los paisajes naturales son transformados y fragmentados en el tiempo. El presente artículo profundiza en la escala local sobre los procesos de transformación del paisaje mediante un estudio integrado del mismo y su evolución durante los últimos 28 años. Los resultados identifican 28 geosistemas en la microcuenca, de los cuales doce contienen un paisaje antrópico y trece conservan un grado de naturalidad alto, así mismo se registró una tendencia a la estabilidad de los procesos de cambio. Los bosques andinos presentan una pérdida de 7,37 ha por año o una tasa de 0,23 %, y las zonas con mayor intervención están asociadas a áreas núcleo, por ende aumentan los efectos de borde y fragmentación. Los resultados permitirán planificar la microcuenca a partir de los procesos históricos de uso y la condición del paisaje, para así facilitar la construcción de alternativas de uso y conservación de los geosistemas.

Possible use of measurements to amend cross section tables (PUMA)

International Nuclear Information System (INIS)

Kherani, N.P.; Bonalumi, R.A.

1983-01-01

In a companion paper, the RAM flux mapping procedure has been demonstrated. RAM combines theory and in-core detector flux measurements, thereby recognizing a difference between the two. Assuming that the RAM ''smoothed-out'' flux distribution is exact, then the discrepancy with purely theoretical fluxes is due to inadequacies in the diffusion theory, homogenised core parameters. PUMA has been devised with the purpose of inferring adjustments in the homogenised core parameters from the theory vs. experiment flux discrepancy. This has been achieved by introducing influence functions similar to those defined by Buckler. A thorough mathematical analysis shows that influence functions are not all linearly independent and that it is crucial to use the criticality equation in the equation set. Numerical examples are shown to demonstrate the procedure

Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53

Science.gov (United States)

Charvet, Céline; Wissler, Manuela; Brauns-Schubert, Prisca; Wang, Shang-Jui; Tang, Yi; Sigloch, Florian C.; Mellert, Hestia; Brandenburg, Martin; Lindner, Silke E.; Breit, Bernhard; Green, Douglas R.; McMahon, Steven B.; Borner, Christoph; Gu, Wei; Maurer, Ulrich

2011-01-01

Summary Activation of p53 by DNA damage results in either cell cycle arrest, allowing DNA repair and cell survival, or induction of apoptosis. As these opposite outcomes are both mediated by p53 stabilization, additional mechanisms to determine this decision must exist. Here we show that glycogen synthase kinase-3 (GSK-3) is required for the p53-mediated induction of the pro-apoptotic BH3 only-protein PUMA, an essential mediator of p53-induced apoptosis. Inhibition of GSK-3 protected from cell death induced by DNA damage and promoted increased long-term cell survival. We demonstrate that GSK-3 phosphorylates serine 86 of the p53-acetyltransferase Tip60. A Tip60S86A mutant was less active to induce p53 K120 acetylation, Histone 4 acetylation and expression of PUMA. Our data suggest that GSK-3 mediated Tip60S86-phosphorylation provides a link between PI3K signaling and the choice for or against apoptosis induction by p53. PMID:21658600

Impact of burnout and psychosocial work characteristics on future long-term sickness absence. Prospective results of the Danish PUMA-study among human service workers

DEFF Research Database (Denmark)

Borritz, Marianne; Christensen, KB; Bültmann, Ute

2010-01-01

and Job satisfaction) followed up during the proceeding 18 months regarding onset of long-term sickness absence. Questionnaire data regarding burnout and psychosocial factors were aggregated at work unit level. We used Poisson regression models with psychosocial factors and burnout as predictors of long...... work environment, and equally important, the organizations should be attentive to employees with symptoms of burnout......Objectives: The objective of this study was to examine if burnout and psychosocial factors predicted long-term sickness absence (>2 weeks) at work unit level. Methods: Data were collected prospectively at 82-work units in human services (PUMA cohort, PUMA: Danish acronym for Burnout, Motivation...

Anfibios andinos del Perú fuera de Áreas Naturales Protegidas: amenazas y estado de conservación

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César Aguilar

2011-05-01

Full Text Available Presentamos una lista actualizada de los anfibios presentes en Perú y para las especies andinas (con distribución altitudinal sobre los 1000 m de altitud se informa sobre su categoría según la UICN, los endémicos de Perú, sus amenazas y su presencia dentro del SINANPE. Hasta el año 2010 se conocen 538 especies de anfibios; 110 especies fueron registradas entre el año 2003 y el 2010; aproximadamente una especie descrita por mes. De las 110 especies descritas desde el 2003, 77 fueron andinas y 64% de éstas se encuentran fuera del SINANPE. En total son reconocidas 235 especies andinas, el 80% son endémicas de Perú y 58% de éstas se encuentran fuera del SINANPE. Noventaiun especies andinas están en categorías de amenaza y en la categoría de Casi Amenazado, y 53% de éstas se encuentran fuera del SINANPE. Los géneros Telmatobius y Atelopus, así como las familias Centrolenidae y Strabomantidae, presentan los porcentajes más altos de especies andinas con categorías de amenaza y Casi Amenazado. Para 83 (36% especies de anfibios andinos presentes en Perú, la principal amenaza es la pérdida del hábitat. Otras amenazas que se presentan en menores porcentajes son la quitridiomicosis, degradación del hábitat y sobrexplotación. Se recomienda el fomento de áreas de conservación privadas para las especies de anfibios andinos presentes en Perú con categorías de amenaza, endémicas y que no están dentro del SINANPE.

Indicios indirectos de la presencia del oso andino (Tremarctos ornatus Cuvier, 1825 en el noroeste de Argentina Indirect evidence on the presence of the Andean bear (Tremarctos ornatus Cuvier, 1825 in northwestern Argentina

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J. Fernando Del Moral

2009-06-01

Full Text Available La presencia de osos andinos (Tremarctos ornatus en Argentina ha sido muy discutida debido a la ausencia de evidencia confirmativa. Muchos expertos en el oso dudan actualmente de su presencia en el país. No obstante, la Selva Tucumano-Boliviana o de Yungas es un ecosistema típico donde se puede encontrar esta especie; particularmente en el área estudiada, el hábitat parece ser de alta calidad para los osos. Entre los años 2001 y 2006, se recopilaron 23 casos de evidencia sobre la presencia de osos andinos en las provincias de Salta y Jujuy. Se registraron huellas, restos alimenticios y heces. Adicionalmente, se entrevistó a nativos, agricultores y cazadores para colectar otros datos sobre la especie. Se concluye que las selvas de Yungas del extremo noroeste de Argentina, deben ser consideradas un área con alta probabilidad de mantener una población residente de osos andinos. Aunque posiblemente esta sea una población aislada y pequeña, la presencia permanente de osos andinos en el noroeste de Argentina no debería ser puesta en duda.The presence of Andean bears (Tremarctos ornatus in Argentina has been disputed due to the absence of confirming evidence. Many Andean bear experts currently doubt on their presence in this country. Nevertheless, the Tucuman-Bolivian Forest or Yungas is a typical ecosystem where this species can be found, particularly in the studied area, in which the habitat appears to be of high quality for bears. Between 2001 and 2006, 23 cases of evidence on the presence of Andean bears in the provinces of Salta and Jujuy were recorded. Footprints, food remains and scats were found. In addition, natives, farmers, and hunters where interviewed to collect new data of this species. The conclusion is that the Yungas Forest of northwestern Argentina must be considered an area with high probability of maintaining a resident population of Andean bears. Although this is probably a small and perhaps isolated population, the

Estudio de la Maca (Lepidium meyenii Walp., cultivo andino con propiedades terapéuticas

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Gabriel Sifuentes-Penagos

2015-01-01

Full Text Available La maca es un producto originario de los Andes Centrales del Perú, resistente a granizadas, heladas y sequías prolongadas. Se cultiva desde la época incaica en altitudes comprendidas entre los 3800 a 4500 m.s.n.m. Esta planta herbácea, presenta no sólo un alto valor nutricional sino también es valorada por su papel medicinal. Entre los componentes químicos de este cultivo andino que se han relacionado con sus acciones terapéuticas como el aumento de la fertilidad, niveles de energía, acción antioxidante, mejora del deseo sexual y la tasa de crecimiento, destacan: los glucosinolatos, esteroles, ácidos grasos (macaeno y sus respectivas amidas (macamidas, alcaloides (lepidilinas A y B, macaridina y polifenoles. El objetivo de este trabajo fue, recopilar las diferentes investigaciones que se han llevado a cabo sobre las propiedades terapéuticas de la maca y los compuestos responsables de las mismas.

Estructuras agrarias comparadas: la Puna argentina y el sur boliviano a comienzos del siglo XX

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Ana A. Teruel

2005-01-01

Full Text Available This article expects to be another contribution to the knowledge about the social-economic problems from the Argentine Puna, especifically to its agricultural structure, paying special attention to changes and permanences, concerning to property and land, key to economical and social power and fundamental axis of production relationship of this society. It focuses on the problematical fact of indian lands, making a comparison between the North of Argentina and the South of Bolivia, considering both political state systems about comunity lands and its effects in the agrarian structures in the begining of the XXth century.Este artículo tiene por propósito realizar un aporte más al conocimiento de la problemática socio-económica de la Puna argentina, específicamente a su estructura agraria, atendiendo los cambios y permanencias relativos a la propiedad y tenencia de la tierra, clave del poder económico y social y eje fundamental en las relaciones de producción de esta sociedad agraria. Se trata la cuestión en el marco de la problemática de las tierras indígenas, comparando la situación del Norte argentino con la del Sur boliviano, analizando las políticas de ambos Estados en torno a la tierra de las comunidades y sus efectos en las estructuras agrarias de comienzos del siglo XX.

Puma (Herpailurus) pumoides (Castellanos, 1958) nov. comb: Comentarios sistemáticos y registro fósil

OpenAIRE

Chimento, Nicolás R; Derguy, Maria Rosa; Hemmer, Helmut

2014-01-01

Entre los Felinae de procedencia dudosa descritos para Argentina se encuentra Felis pumoides Castellanos 1958, hallado en estratos asignados al Plioceno ("horizonte Brocherense”) de la provincia de Córdoba (Argentina). Los restos craneanos y post-craneanos que posee el ejemplar tipo (MUFyCA 767) fueron comparados primeramente con todos los felinos sudamericanos y con Acinonyx jubatus concluyendo que posee un gran parecido a la especie actual Puma (Herpailurus) yagouaroundi, con algunos rasgos...

PUMA Development through a Multi physics Approach

International Nuclear Information System (INIS)

Cheon, Jinsik; Kim, Junehyung; Lee, Byoungoon; Lee, Chanbock

2013-01-01

Meanwhile advances of numerical methods make it possible for the multi physics problem to be solved in a fully coupled way. In addition to a multidimensional, multi physical approach, a nuclear fuel performance analysis code, which is 1D code, should be improved by accommodating the state-of-the-art in the numerical analysis to support current fuel design and performance analysis. In particular, the coupling between the mechanical equilibrium equation and a set of numerically stiff kinetics equations for fission gas release is of great importance for a multi physics simulation of nuclear fuel. Instead, coupling between temperature and fuel constituent was found to be made with a relative ease by employing an ordinary differential equations solver. As an effort for a new SFR metal fuel performance analysis code, called PUMA (Performance of Uranium Metal fuel rod Analysis code), the deformation of U-Zr fuel for SFR in connection with a fission gas release model is analyzed. A finite element analyses for purely mechanical problems are performed using a backward differentiation formula, and are subjected to scrupulous verification with Abaqus. Then mechanical equilibrium equation and the equations for fission gas release are coupled with the same differential-algebraic equations (DAE) solver

Contesting the Equivalency of Continuous Sedation until Death and Physician-assisted Suicide/Euthanasia: A Commentary on LiPuma.

Science.gov (United States)

Raho, Joseph A; Miccinesi, Guido

2015-10-01

Patients who are imminently dying sometimes experience symptoms refractory to traditional palliative interventions, and in rare cases, continuous sedation is offered. Samuel H. LiPuma, in a recent article in this Journal, argues that continuous sedation until death is equivalent to physician-assisted suicide/euthanasia based on a higher brain neocortical definition of death. We contest his position that continuous sedation involves killing and offer four objections to the equivalency thesis. First, sedation practices are proportional in a way that physician-assisted suicide/euthanasia is not. Second, continuous sedation may not entirely abolish consciousness. Third, LiPuma's particular version of higher brain neocortical death relies on an implausibly weak construal of irreversibility--a position that is especially problematic in the case of continuous sedation. Finally, we explain why continuous sedation until death is not functionally equivalent to neocortical death and, hence, physician-assisted suicide/euthanasia. Concluding remarks review the differences between these two end-of-life practices. © The Author 2015. Published by Oxford University Press, on behalf of the Journal of Medicine and Philosophy Inc. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Sensitivity of landscape resistance estimates based on point selection functions to scale and behavioral state: Pumas as a case study

Science.gov (United States)

Katherine A. Zeller; Kevin McGarigal; Paul Beier; Samuel A. Cushman; T. Winston Vickers; Walter M. Boyce

2014-01-01

Estimating landscape resistance to animal movement is the foundation for connectivity modeling, and resource selection functions based on point data are commonly used to empirically estimate resistance. In this study, we used GPS data points acquired at 5-min intervals from radiocollared pumas in southern California to model context-dependent point selection...

Niveles de satisfacción de los usuarios del Hospital Andino Alternativo de Chimborazo

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Basantes-Avalos, René

2016-06-01

Full Text Available To be competitive in the present world, it should be offered goods and services of quality, therefore the efforts of enterprises should be focused on the customer, by knowing their needs, providing value-added solutions and a level of excellence that satisfies them, and thus ensure their loyalty. Alternative Andino Hospital of Chimborazo, Ecuador, which is a new institution in the area of health, performs procedures for continuous improvement when providing their service, but it does not know for sure what the opinions of its customers about the quality of the received service are. That is why, a research that analyzes the perceptions of customers, using the SERVPERF model was made, this model owes its name to the exclusive attention paid to performance assessment to measure the quality of service, although it consists of the same items and dimensions as SERVQUAL, the only difference is that it eliminates the part that refers to expectations of customers. Once analyzed the items of security, empathy, tangibility, reliability and responsiveness; the best one is safety, followed closely by reliability.

Estados sin nación. El discurso nacionalista y el evolucionismo andino, 1890-1930

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Paul Juan Montoya Vásquez

2008-06-01

Full Text Available The objective of this essay is to analyze the relationship between the nationalist pronouncements in Ecuador, Peru and Bolivia, and the debate center on European evolutionism at the end of the 19th and 20th centuries. The essay, introductory in nature, presents some aspects of the recent debate on the genealogic discourse of nationalism as well as some important bibliographic references concerning these issues.//El artículo propone un análisis de las relaciones entre el discurso nacionalista en los países centro andinos (Ecuador, Perú, Bolivia y el debate en torno a las tesis del evolucionismo europeo, a fines del siglo XIX e inicios del XX, centrado en el problema de la “integración de las mayorías” a la vida o dinámica nacional. Por ser de carácter introductorio se avoca a presentar algunos elementos del debate reciente sobre el discurso genealógico del nacionalismo así como parte importante de la bibliografía dedicada al tema en los referidos medios.

Alcance del principio de eficacia directa del derecho comunitario andino en el ámbito de la propiedad industrial y del derecho del consumidor en el ordenamiento jurídico colombiano

OpenAIRE

Pachón Guerrero, Juan Sebastián

2017-01-01

Tesis sobre el alcance del principio de eficacia directa del derecho comunitario andino en el ámbito de la propiedad industrial y del derecho del consumidor en el ordenamiento jurídico colombiano Thesis related to the scope of the principle of direct effectiveness of andean community law in the field of industrial property and consumer law in the Colombian legal system

LA EVIDENCIALIDAD EN EL CASTELLANO ANDINO NARIÑENSE EVIDENTIALITY IN THE CASTILIAN SPANISH OF THE ANDEAN REGION OF NARIÑO

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Ómar Andrés Portilla Melo

2010-12-01

Full Text Available Resumen En este texto se hace una descripción de un fenómeno de transferencia semánticopragmática a nivel modal del quechua al castellano andino de la región nariñense. El trabajo está organizado de la siguiente manera: en primer lugar, se introduce el concepto de evidencialidad; después, se hace una breve descripción histórica del quechua y una introducción a su tipología, y, finalmente, se explica la manera en que el contacto lingüístico quechua-español le dio al castellano andino nariñense los aspectos que lo caracterizan. La metodología usada fue la entrevista etnográfica. Como resultado se obtuvo que la influencia del quechua en el castellano del departamento de Nariño no se dio solamente a nivel léxico o sintáctico, sino que alcanzó niveles más profundos.Abstract The article describes a phenomenon of semantic-pragmatic transfer at the modal level from Quechua into the Castilian Spanish of the Andean region of Nariño. The article is organized as follows: first it introduces the concept of evidentiality, next it provides a brief historical description of Quechua and an introduction to its typology, and, finally, it explains how the linguistic contact between Quechua and Spanish gave the Castilian Spanish of the Andean region of Nariño its characteristic aspects. The methodology used was the ethnographic interview. The results obtained show that the influence of Quechua on the Castilian Spanish of the department of Nariño occurred not only at the lexical or syntactic levels, but also at deeper levels.

Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1

Energy Technology Data Exchange (ETDEWEB)

Jenson, Justin M.; Ryan, Jeremy A.; Grant, Robert A.; Letai, Anthony; Keating, Amy E. (DFCI); (MIT)

2017-06-08

Overexpression of anti-apoptotic Bcl-2 family proteins contributes to cancer progression and confers resistance to chemotherapy. Small molecules that target Bcl-2 are used in the clinic to treat leukemia, but tight and selective inhibitors are not available for Bcl-2 paralog Bfl-1. Guided by computational analysis, we designed variants of the native BH3 motif PUMA that are > 150-fold selective for Bfl-1 binding. The designed peptides potently trigger disruption of the mitochondrial outer membrane in cells dependent on Bfl-1, but not in cells dependent on other anti-apoptotic homologs. High-resolution crystal structures show that designed peptide FS2 binds Bfl-1 in a shifted geometry, relative to PUMA and other binding partners, due to a set of epistatic mutations. FS2 modified with an electrophile reacts with a cysteine near the peptide-binding groove to augment specificity. Designed Bfl-1 binders provide reagents for cellular profiling and leads for developing enhanced and cell-permeable peptide or small-molecule inhibitors.

Startup transient simulation for natural circulation boiling water reactors in PUMA facility

International Nuclear Information System (INIS)

Kuran, S.; Xu, Y.; Sun, X.; Cheng, L.; Yoon, H.J.; Revankar, S.T.; Ishii, M.; Wang, W.

2006-01-01

In view of the importance of instabilities that may occur at low-pressure and -flow conditions during the startup of natural circulation boiling water reactors, startup simulation experiments were performed in the Purdue University Multi-Dimensional Integral Test Assembly (PUMA) facility. The simulations used pressure scaling and followed the startup procedure of a typical natural circulation boiling water reactor. Two simulation experiments were performed for the reactor dome pressures ranging from 55 kPa to 1 MPa, where the instabilities may occur. The experimental results show the signature of condensation-induced oscillations during the single-phase-to-two-phase natural circulation transition. The results also suggest that a rational startup procedure is needed to overcome the startup instabilities in natural circulation boiling water reactor designs

Parámetros genético poblacionales en seis especies de Felidae neotropicales ( Leopardus tigrina, L. wiedii, L. pardalis, Herpailurus jagouroundi, Puma concolor y Pantera onca

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M. Ruiz-García

2001-07-01

Full Text Available Se analizaron 196 muestras pertenecientes a 68 Leopardus pardalis (Ocelote; Colombia, Perú, a12 L. wiedi (Margay; Colombia y Bolivia, a 24 L. tigrinus (Tigrillo; Colombia, a 16 Herpailurus jagouroundi (yagouroundi; Colombia, Venezuela, Brasil a 50 Puma concolor (Puma; Colombia, Perú, Bolivia y a 24 Panthera onca (Jaguar; Colombia con 6 marcadores microsatélites diferentes (FCA08, FCA43, FCA45, FCA90, FCA96 y FCA126. Los resultados y conclusiones más obvias fueron las siguientes: (1 Para la mayoría de esas especies no se dio equilibrio Hardy- Weinberg cuando se analizaron individuos de localidades diferentes por exceso de homocigotos. Probablemente, el efecto Wahlund es responsable de ese hecho.

Attitudes toward jaguars and pumas and the acceptability of killing big cats in the Brazilian Atlantic Forest: An application of the Potential for Conflict Index2.

Science.gov (United States)

Engel, Monica T; Vaske, Jerry J; Bath, Alistair J; Marchini, Silvio

2017-09-01

We explored the overall acceptability of killing jaguars and pumas in different scenarios of people-big cat interactions, the influence of attitudes toward big cats on acceptability, and the level of consensus on the responses. Data were obtained from 326 self-administered questionnaires in areas adjacent to Intervales State Park and Alto Ribeira State Park. Overall, people held slightly positive attitudes toward jaguars and pumas and viewed the killing of big cats as unacceptable. However, individuals that held negative attitudes were more accepting of killing. As the severity of people-big cat interactions increased, the level of consensus decreased. Knowing whether killing a big cat is acceptable or unacceptable in specific situations allows managers to anticipate conflict and avoid illegal killing of big cats.

Response to LiPuma and DeMarco’s Article on “Hastening Death”

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Julia Zenz

2017-05-01

Full Text Available The paper “Palliative care and patient autonomy: moving beyond prohibitions against hastening death” by LiPuma and DeMarco deals with an aspect of end of life care which is the source of considerable disagreement. It is important to emphasize that autonomy is not the unique feature for end of life care. There is always a medical and ethical commitment to care, i.e. beneficence and nonmaleficence. All of these aspects have to be taken into account when treating patients at the very end of life. There is considerable scientific proof indicating that most patients and families can experience a death in dignity when being cared for in palliative care or hospice units.

Novel type of neutron polarization analysis using the multianalyzer-equipment of the three-axes spectrometer PUMA

Science.gov (United States)

Schwesig, Steffen; Maity, Avishek; Sobolev, Oleg; Ziegler, Fabian; Eckold, Götz

2018-01-01

The combination of polarization analysis and multianalyzer system available at the three axes spectrometer PUMA@FRM II allows the simultaneous determination of both spin states of the scattered neutrons and the absolute value of the polarization. The present paper describes the technical details along with the basic formalism used for the precise calibration. Moreover, the performance of this method is illustrated by several test experiments including first polarized inelastic studies of the magnetic excitations of CuO in the multiferroic and the uniaxial antiferromagnetic phases.

¿ES EL COMPORTAMIENTO RELIGIOSO ANDINO PRODUCTO DE FACTORES ECONÓMICOS?

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Jazmín Tavera Colonna

2015-04-01

Full Text Available Sudamérica atravesada por los Andes presenta un contexto rico en diversidad pero incierto. Los fuertes cambios climáticos y terremotos han determinado cambios drásticos en la cosmogonía andina, así las primeras culturas andinas desarrolladas a orillas del mar le dan la espalda y reorientan sus dioses a los nevados de la cordillera. La escritura por su poder de comunicación en el tiempo ha revestido un cierto poder mágico para diferentes culturas. Las gracias impresas son agradecimientos a Dios o a los Santos por los favores concedidos. Al evaluar para Perú, el impacto de variables macroeconómicas sobre la cantidad de gracias por motivos económicos en sectores de clase media, encontramos que sólo los factores que reflejan el animismo andino guardan un impacto significativo. Ello sería el reflejo de un marco institucional débil en el que un individuo encuentra en la religión una institucionalidad legítima que le ofrece respuestas a necesidades básicas para su supervivencia como tal. El sincretismo religioso logró establecer el catolicismo en la Sudamérica andina, pero con una interesante reinterpretación, en la que la naturaleza y los ancestros siguen ocupando un lugar preponderante, sus señales son más claras que la de las instituciones que norman su sociedad.

Simulasi Penggunaan Ipv6 Pada PD. Pumas Jaya Menggunakan Metode Manual Tunneling

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Elidjen Elidjen

2010-12-01

Full Text Available Internet usage trends with IPv4 addresses that only have 32-bit addresses could no longer cope with the large allocation of the required addresses. Internet Engineering Task Force (IETF has issued a new standard of Internet protocol called IPv6 to anticipate this problem. PD. Pumas Jaya, which started in 1996 in the field of marine products in particular marinated seafood, such as salted fish, rebon shrimp, cuttlefish, anchovies and other marine products to anticipate the need for this in its network. However, IPv6 can not simply be used to replace IPv4 as the existing network infrastructure with IPv4. This research discussed IPv6 simulation tunneling with manual methods so that an IPv6 site can communicate with other IPv6 site even if separated by an infrastructure that supports only IPv4. 

Pequeña historia de un proyecto utópico: el Movimiento del Nuevo Cine y Video Boliviano y su Revista Imagen

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María Gabriela Aimaretti

2018-01-01

Full Text Available En el marco de una investigación más amplia que releva, describe y analiza las prácticas de producción audiovisual en La Paz, Bolivia, entre 1978 y 1989, el presente trabajo se centra en historiar el proyecto editorial Imagen: una revista de cine que publicó el Movimiento del Nuevo Cine y Video Boliviano durante la segunda mitad de la década del ochenta. Sin tradición local en lo que refiere a publicaciones dedicadas al cine, Imagen fue una iniciativa autogestiva y autofinanciada, que funcionó con una frecuencia y formato variable, y sirvió como foro de discusión sobre temas específicos del quehacer local, vehículo de difusión de actividades del Movimiento, microespacio de formación, medio de circulación de convocatorias y concursos, y herramienta de articulación entre distintas propuestas. El trabajo explica su devenir histórico, describe sus caracteres generales y perfil editorial, da cuenta de los actores intervinientes y sus formas de organización, y señala las condiciones de posibilidad, alcances y limitaciones del proyecto.

Forward Models for Following a Moving Target with the Puma 560 Robot Manipulator

Directory of Open Access Journals (Sweden)

Daniel Fernando Tello Gamarra

2015-12-01

Full Text Available This paper describes how a forward model could be applied in a manipulator robot to accomplish the task of following a moving target. The forward model has been implemented in the puma 560 robot manipulator in simulation after a babbling motor phase using ANFIS neural networks. The forward model delivers a rough estimation of the position in the operational space of a moving target. Using this information a Cartesian controller tracks the moving target. An implementation of the proposed architecture and the Piepmeir algorithm for the problem of following a moving target is also shown in the paper. The control architecture proposed in this paper was also tested with MLP and RBF neural networks. Results and simulations are shown to demonstrate the applicability of our proposed architecture for tracking a moving target.

Determinación de la capacidad antioxidante y compuestos fenólicos de cereales andinos: quinua (Chenopodium quinoa), kañiwa (Chenopodium pallidicaule) y kiwicha (Amaranthus caudatus)

OpenAIRE

Repo de Carrasco, Ritva; Encina Zelada, Christian Rene

2008-01-01

Se realizó la extracción de compuestos hidrofílicos y lipofílicos de cereales andinos, siendo el de mayor contenido en ambos casos la muestra de kañiwa (Chenopodium pallidicaule variedad cupi), siguiendo la de quinua (Chenopodium quinoa ecotipo marrón) y finalmente la kiwicha (Amaranthus caudatus ecotipo negra). Se realizó la determinación del contenido de compuestos fenólicos en quince variedades de quinua, siendo la de mayor contenido la variedad PIQ031046 con 139,94 mg ácido gálico/100 g; ...

CARACTERIZACIÓN DE LA ACUMULACIÓN DE CARBONO EN PEQUEÑOS HUMEDALES ANDINOS EN LA CUENCA ALTA DEL RÍO BARBAS (QUINDÍO, COLOMBIA)

OpenAIRE

María Cecilia Roa-García; Sandra Brown

2016-01-01

Se caracterizó el proceso de acumulación de carbono en pequeños humedales andinos de la cuenca alta del río Barbas, en el municipio de Filandia, departamento del Quindío, Colombia. El método de bolsas de descomposición se usó para estimar las tasas de acumulación de materia orgánica y las constantes de descomposición en el corto plazo. La pérdida por ignición y la datación con carbono 14 se usaron para calcular las tasas de acumulación de carbono en el largo plazo. Los 52 humedales ocupan un ...

Diferenciación étnica y redes de larga distancia entre migrantes andinos: el caso de Sanka y Colcha

Directory of Open Access Journals (Sweden)

1991-01-01

Full Text Available DIFFERENTIATION ETHNIQUE ET RESEAUX DE LONGUE DISTANCE CHEZ LES MIGRANTS ANDINS : LE CAS DE “SANKA” ET “COLCHA”. Les migrants andins ne limitent pas leurs réseaux sociaux d’interaction au milieu urbain. La réorientation spatiale des migrants devient notable au moment de l’aggravation de la crise nationale au Pérou qui affecte avec une particulière dureté la population liménienne. La formation de nouveaux réseaux de longue distance entre migrants est déterminée historiquement par l’espace géographique que couvre l’histoire de leur migration. De tels réseaux d’interaction impliquent un mécanisme spécifique de reproduction sociale des migrants andins et constituent un facteur important de changement social. Los migrantes andinos en Lima no limitan sus redes sociales de interacción al centro urbano. Sobre todo con la agudización de la crisis nacional en el Perú, que afecta con particular dureza a la población limeña, comienza una notable reorientación espacial de los migrantes. La formación de nuevas redes de larga distancia entre migrantes es históricamente determinada por el espacio geográfico que cubre su historia migracional. Tales redes de interacción significan un mecanismo específico de reproducción social de migrantes andinos y son factor importante del cambio social. ETHNIC DIFFERENTIATION AND LONG-DISTANCE-NETWORKS BETWEEN ANDEAN MIGRANTS: THE CASE OF “SANKA” AND “COLCHA”. The andean migrants in Lima do not limit their social networks of interaction on the urban center. Together with the aggravation of the national crisis in Peru, which affects the urban population of Lima particularly hard, is emerging a remarkable spatial reorientation of those migrants. The formation of long-distance-networks between migrants is historically determined by the geographical space, which covers their migration history. Such networks of interaction suggest a specific form of social reproduction of the andean migrants

La delegación del Poder Tributario en el Poder Ejecutivo, su regulación en el Perú y en otros países andinos

OpenAIRE

Urquizo Maggia, Daniel Fernando

2009-01-01

La presente tesis que lleva por título “La delegación del Poder Tributario en el Poder Ejecutivo, su regulación en el Perú y en otros países andinos” trata sobre la delegación legislativa tributaria regulada en los artículos 74 y 104 de la Carta del Perú aprobada en el año 1993, y en los países andinos de Bolivia, Colombia, Ecuador y Venezuela. La doctrina admite que el poder tributario ya no es atribución exclusiva del Poder Legislativo, que originariamente gozaba de esta facu...

Generic Techniques for the Calibration of Robots with Application of the 3-D Fixtures and Statistical Technique on the PUMA 500 and ARID Robots

Science.gov (United States)

Tawfik, Hazem

1991-01-01

A relatively simple, inexpensive, and generic technique that could be used in both laboratories and some operation site environments is introduced at the Robotics Applications and Development Laboratory (RADL) at Kennedy Space Center (KSC). In addition, this report gives a detailed explanation of the set up procedure, data collection, and analysis using this new technique that was developed at the State University of New York at Farmingdale. The technique was used to evaluate the repeatability, accuracy, and overshoot of the Unimate Industrial Robot, PUMA 500. The data were statistically analyzed to provide an insight into the performance of the systems and components of the robot. Also, the same technique was used to check the forward kinematics against the inverse kinematics of RADL's PUMA robot. Recommendations were made for RADL to use this technique for laboratory calibration of the currently existing robots such as the ASEA, high speed controller, Automated Radiator Inspection Device (ARID) etc. Also, recommendations were made to develop and establish other calibration techniques that will be more suitable for site calibration environment and robot certification.

Feline infectious peritonitis in a mountain lion (Puma concolor), California, USA.

Science.gov (United States)

Stephenson, Nicole; Swift, Pamela; Moeller, Robert B; Worth, S Joy; Foley, Janet

2013-04-01

Feline infectious peritonitis (FIP) is a fatal immune-mediated vasculitis of felids caused by a mutant form of a common feline enteric virus, feline enteric coronavirus. The virus can attack many organ systems and causes a broad range of signs, commonly including weight loss and fever. Regardless of presentation, FIP is ultimately fatal and often presents a diagnostic challenge. In May 2010, a malnourished young adult male mountain lion (Puma concolor) from Kern County, California, USA was euthanized because of concern for public safety, and a postmortem examination was performed. Gross necropsy and histopathologic examination revealed necrotizing, multifocal myocarditis; necrotizing, neutrophilic, and histiocytic myositis and vasculitis of the tunica muscularis layer of the small and large intestines; and embolic, multifocal, interstitial pneumonia. Feline coronavirus antigen was detected in both the heart and intestinal tissue by immunohistochemistry. A PCR for coronavirus performed on kidney tissue was positive, confirming a diagnosis of FIP. Although coronavirus infection has been documented in mountain lions by serology, this is the first confirmed report of FIP.

Calculation of the CAREM reactor with the HUEMUL-PUMA-THERMIT chain of codes; Calculo del reactor CAREM con la cadena de codigos HUEMUL-PUMA-THERMIT

Energy Technology Data Exchange (ETDEWEB)

Notari, Carla; Grant, Carlos R [Comision Nacional de Energia Atomica, General San Martin (Argentina)

2000-07-01

The purpose of the work was the evaluation of the the CAREM 25 reactor core, using a chain of codes (HUEMUL-PUMA-THERMIT) different to the one used in the original design (CONDOR-CITVAP-THERMIT). First, we performed a partial validation of the our codes in lattices similar to CAREM and reproduced a benchmark for simulation of gadolinium burnup. The results were considered satisfactory for this stage of the project. Then, we calculated the core along the normal operating equilibrium cycle and in hot and cold shut-down conditions. The main outcome of our evaluation confirms the general behaviour of the reference calculations except in one important point referring to the cold shut down. In this condition, the failure of one single rod of bank number 13 of the shut down system, leaves the core in a supercritical state at the beginning of the cycle and this anomaly persists during almost a third of the overall cycle. A new design of the core is proposed with minor modifications of the reference one, without introducing new types of fuel elements and keeping the same fuel management scheme. This new core fulfills all the design requirements. (author)

DESARTICULACIÓN DE DISCURSOS NACIONALISTAS EN EL CINE DE AUTOR BOLIVIANO: 3B´S Y SOCAVÓNCINE

Directory of Open Access Journals (Sweden)

Mariana Lacunza Mendizábal

2017-12-01

Full Text Available Distinta a México, Argentina y Brasil, Bolivia tiene una industria cinematográfica poco desarrollada que no ha logrado consolidarse por varias razones. Entre éstas está la falta de apoyo estatal, el escaso desarrollo profesional en estas áreas y una carencia de cultura cinematográfica y visual en general. Sin embargo, durante la última década, la industria cinematográfica boliviana ha sido partícipe de logros importantes gracias a la aparición de las nuevas tecnologías. Películas digitales hechas por una nueva generación de jóvenes directores reconocidos globalmente se han desarrollado en tres ramas distintas: a cine de autor, b cine documental y c cortometrajes. Al mismo tiempo, la producción de este tipo de filmes se apoya en un esfuerzo colectivo, como es el caso de RAV (Rojo, Amarillo y Verde, 2006 de Rodrigo Bellot, Martín Bolulocq y Sergio Bastani y aquellos filmes producidos por el colectivo SocavónCine desde el año 2013. Este artículo busca explorar cómo el más reciente cine boliviano de autor desarticula discursos de identidad nacional al deconstruir oposiciones binarias. Además,  este artículo busca examinar la aplicabilidad del cine de autor y de las prácticas colaborativas en los “cines pequeños” o “small cinemas” al comparar y contrastar ambos grupos a través del análisis de las formas de producción y corrientes estéticas.

"A carne mais barata do mercado é a carne negra: uma reflexão sobre o "design" das camisas da Puma na Copa do Mundo de Futebol/2010 "The cheapest flesh in the market is the black one": body, soccer and advertising Puma uniforms in the 2010 soccer world cup

Directory of Open Access Journals (Sweden)

Victor Andrade de Melo

2011-06-01

Full Text Available A Puma, uma empresa de material esportivo, desde meados da primeira década do século XXI tem constantemente utilizado jogadores negros em suas campanhas publicitárias, parte de uma estratégia de busca de aproximação com o continente africano. À beira da falência no início dos anos 90, a empresa conseguiu se reposicionar no mercado unindo o esporte à moda, investindo em produtos de "design" arrojado. Uma de suas iniciativas foi buscar inspiração no "caráter exótico" das nações africanas para produzir peças que possam ser utilizadas em situações cotidianas, não só para a prática de esportes. Como o corpo do negro africano tem sido representado em suas estratégias publicitárias? Esse estudo teve por objetivo analisar um ponto específico da publicidade da Puma por ocasião da Copa do Mundo de Futebol de 2010, realizada na África do Sul: o "design" das camisas fornecidas a três seleções africanas - Camarões, Costa do Marfim e Gana. Para alcance do objetivo, entabulamos uma comparação com os modelos das camisas fornecidas pela empresa a outros selecionados (Suíça, Uruguai e Itália, prospectando o quanto suas ações publicitárias reforçam ou não certos estereótipos comumente observados quando se utilizam negros em campanhas de publicidade.Puma, a company of sport gears, has been inserting black soccer players in its advertising campaigns as a strategy to get closer to the African continent. Near to bankruptcy at the 90' beginning, the company has succeeded in bringing to the market products with more daring design, linking fashion and sports. One of its latest initiatives was to seek inspiration in the exotic profile of African people to produce pieces that can be used in all occasions not only for sports. How African's bodies have been exposed in its adverting campaigns? The objective of this study was to analyze an specific issue related to some strategies adopted in Puma advertising campaigns launched during

The concept of fuel cycle integrated molten salt reactor for transmuting Pu+MA from spent LWR fuels

International Nuclear Information System (INIS)

Hirose, Y.; Takashima, Y.

2001-01-01

Japan should need a new fuel cycle, not to save spent fuels indefinitely as the reusable resources but to consume plutonium and miner actinides orderly without conventional reprocessing. The key component is a molten salt reactor fueled with the Pu+MA (PMA) separated from LWR spent fuels using fluoride volatility method. A double-tiered once-through reactor system can burn PMA down to 5% remnant ratio, and can make PMA virtually free from the HAW to be disposed geometrically. A key issue to be demonstrated is the first of all solubility behavior of trifluoride species in the molten fuel salt of 7 LiF-BeF 2 mixture. (author)

Conexões e entrecruzamentos: configurações culturais e direitos em um circuito migratório entre La Paz e Buenos Aires

Directory of Open Access Journals (Sweden)

Sergio Caggiano

2012-04-01

Full Text Available A partir de um conflito entre imigrantes bolivianos em Buenos Aires em torno do “trabalho escravo” nas oficinas de costura da cidade, o artigo trata da relação entre direitos (“ocidentais” e formas culturais aymaras ou andinas. Como são qualificadas essas relações de trabalho quando envolvem trabalhadores e proprietários (ou administradores bolivianos/andinos? A cultura aymara problematiza a ideia de exploração laboral e a exploração laboral problematiza a cultura aymara. O artigo foca o circuito migratório transnacional e a circulação heterogênea que o conforma (pessoas, dinheiro, objetos, saberes e práticas culturais para tentar compreender aquele conflito. Com base na análise da convivência enredada de direitos e traços culturais aymaras, proponho que o cruzamento e a sobreposição de instituições e de “lógicas” culturais, sociais, econômicas e políticas são um componente constitutivo desses processos de circulação.Based upon the study of a conflict that erupted between Bolivian immigrants in Buenos Aires over the concept of “slave labor” in the city’s sweatshops, the present article deals with the relationship between (western rights and Aymara or Andean cultural forms. How are these work relations qualified when they involve Bolivian/Andeanworkers and owners (or administrators? Aymara culture problematizes the concept of labor exploitation and vice versa. The present article focuses on the transnational migratory circuit and heterogeneous circulations (of people, money, objects, knowledge and practices that it contains in order to better comprehend this conflict. Based upon an analysis of the lived, networked experience of rights and Aymara cultural traces, I propose to interlink and juxtapose the social, cultural economic and political logics and institutuions that are constituitive components of these processes of circulation.

“ SITUACIÓN DE LA MUJER EN LA CIENCIA Y LA TECNOLOGÍA EN BOLIVIA Y SU PARTICIPACIÓN EN EL SISTEMA BOLIVIANO DE INNOVACIÓN: CASO DE LA FACULTAD DE CIENCIAS Y TECNOLOGÍA DE LA UNIVERSIDAD MAYOR DE SAN SIMÓN”

OpenAIRE

Carrasco, Gloria

2017-01-01

En las ultimas décadas el concepto de Sistemas de Innovación se ha convertido en una poderosa herramienta para el análisis y la comprensión del rol de la ciencia, la tecnología y la innovación en el desarrollo de las naciones. Bolivia, al igual que numerosos países de América Latina, adopta una estrategia basada en el desarrollo de la ciencia y la tecnología y la construcción del Sistema Boliviano de Innovación. Sin embargo, a lo largo de la historia, las mujeres han sido relegadas de la cien...

Genética e conservação do leão-baio (Puma concolor) no sul do Brasil

OpenAIRE

Camila Schlieper de Castilho

2010-01-01

O leão-baio (Puma concolor), segundo maior felino neotropical, tem a maior distribuição geográfica nas Américas. A subespécie que ocorre no sul do Brasil é listada como least concern e vulnerável nas listas de espécies ameaçadas da IUCN e do Ministério do Meio Ambiente brasileiro, respectivamente. Em áreas nas quais a onça-pintada (Panthera onca) foi localmente extinta, o leão-baio tem o papel de predador de topo de cadeia alimentar influenciando na manutenção de processos do ecossistema e na...

Concurrent acetylation of FoxO1/3a and p53 due to sirtuins inhibition elicit Bim/PUMA mediated mitochondrial dysfunction and apoptosis in berberine-treated HepG2 cells

Energy Technology Data Exchange (ETDEWEB)

Shukla, Shatrunajay [Herbal Research Section, CSIR — Indian Institute of Toxicology Research, Post Box No. 80, Mahatma Gandhi Marg, Lucknow‐226001 (India); Department of Medical Elementology and Toxicology, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi ‐110062 (India); Sharma, Ankita [Herbal Research Section, CSIR — Indian Institute of Toxicology Research, Post Box No. 80, Mahatma Gandhi Marg, Lucknow‐226001 (India); Pandey, Vivek Kumar [Herbal Research Section, CSIR — Indian Institute of Toxicology Research, Post Box No. 80, Mahatma Gandhi Marg, Lucknow‐226001 (India); Academy of Scientific and Innovative Research (India); Raisuddin, Sheikh [Department of Medical Elementology and Toxicology, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi ‐110062 (India); Kakkar, Poonam, E-mail: kakkarp59@gmail.com [Herbal Research Section, CSIR — Indian Institute of Toxicology Research, Post Box No. 80, Mahatma Gandhi Marg, Lucknow‐226001 (India); Academy of Scientific and Innovative Research (India)

2016-01-15

Post-translational modifications i.e. phosphorylation and acetylation are pivotal requirements for proper functioning of eukaryotic proteins. The current study aimed to decode the impact of acetylation/deacetylation of non-histone targets i.e. FoxO1/3a and p53 of sirtuins (NAD{sup +} dependent enzymes with lysine deacetylase activity) in berberine treated human hepatoma cells. Berberine (100 μM) inhibited sirtuins significantly (P < 0.05) at transcriptional level as well as at translational level. Combination of nicotinamide (sirtuin inhibitor) with berberine potentiated sirtuins inhibition and increased the expression of FoxO1/3a and phosphorylation of p53 tumor suppressor protein. As sirtuins deacetylate non-histone targets including FoxO1/3a and p53, berberine increased the acetylation load of FoxO1/3a and p53 proteins. Acetylated FoxO and p53 proteins transcriptionally activate BH3-only proteins Bim and PUMA (3.89 and 3.87 fold respectively, P<0.001), which are known as direct activator of pro-apoptotic Bcl-2 family protein Bax that culminated into mitochondria mediated activation of apoptotic cascade. Bim/PUMA knock-down showed no changes in sirtuins' expression while cytotoxicity induced by berberine and nicotinamide was curtailed up to 28.3% (P < 0.001) and it restored pro/anti apoptotic protein ratio in HepG2 cells. Sirtuins inhibition was accompanied by decline in NAD{sup +}/NADH ratio, ATP generation, enhanced ROS production and decreased mitochondrial membrane potential. TEM analysis confirmed mitochondrial deterioration and cell damage. SRT-1720 (1–10 μM), a SIRT-1 activator, when pre-treated with berberine (25 μM), reversed sirtuins expression comparable to control and significantly restored the cell viability (P < 0.05). Thus, our findings suggest that berberine mediated sirtuins inhibition resulting into FoxO1/3a and p53 acetylation followed by BH3-only protein Bim/PUMA activation may in part be responsible for mitochondria

Relaciones entre democracia y desarrollo en los países andinos. Una reflexión desde la economía política

Directory of Open Access Journals (Sweden)

Moncayo Jiménez, Édgard

2006-06-01

Full Text Available En los países andinos, la gobernabilidad democrática de los dos últimos decenios contrasta agudamente con los bajos niveles de crecimiento económico y el aumento del desempleo y la pobreza. Este artículo plantea que el nudo gordiano de esa paradoja es la gran desigualdad en la distribución del ingreso. Causa y consecuencia del mal funcionamiento del sistema político y de la economía, porque las élites económicas controlan el poder político, y crean instituciones y políticas que reflejan el interés de los dueños de la riqueza y no el interés común. Así se crea un círculo vicioso en el que la democracia ¿controlada¿ reproduce y amplía las desigualdades que la engendraron.

Cuando pobreza y género confluyen en el contexto educativo rural andino

Directory of Open Access Journals (Sweden)

Beatriz Alvarado

2010-12-01

Full Text Available A pesar de haberse expandido las oportunidades educativas en el Perú andino durante las dos últimas décadas, la educación rural aún presenta problemas crónicos como una inadecuada inclusión de la niña y la joven en el sistema educativo. El mercado laboral tampoco les ofrece un panorama esperanzador luego de culminar la escuela, si tienen la posibilidad de hacerlo. Este artículo analiza los factores socio-económicos y educativos que impactan la permanencia o fracaso escolar de la joven andina en el Perú rural. Se señalan tres temas emergentes en el análisis y reflexión de esta realidad: brechas de género en el contexto educativo, pobreza y ruralidad así como políticas sensibles al género. Se concluye con sugerencias concretas para la toma de acciones inmediatas que tengan en cuenta la inclusión de todas las voces en la sociedad. Despite the fact that Andean Peru has expanded educational opportunities during the last two decades, rural education still presents serious problems as an inappropriate inclusion of girls and young women into the system of education. Moreover, the labor market does not offer to them an encouraging panorama after graduating from school, even if they have the chance to do so. This article analyzes the educational and socioeconomic factors that strike the permanence or school failure of young women´s in Peruvian rural. Three emerging topics are analyzed and considered on this context: gender gaps in the educational context, poverty and rurality, and gender-sensitive policies. The article draws some conclusions providing concrete recommendations for an urgent action-taking for the inclusion of all the voices in the society.

Caracterización de la circulación atmosférica y la temperatura superficial del mar asociadas a extremos de caudal de ríos andinos y su variabilidad en baja frecuencia

OpenAIRE

Araneo, Diego C.

2006-01-01

El objetivo principal del presente trabajo se centra en determinar los mecanismos asociados a la variabilidad de los caudales de los ríos andinos en relación con la circulación atmosférica y la Temperatura Superficial del Mar (TSM) como forzante del sistema climático. Para la circulación atmosférica el estudio se extiende desde la escala sinóptica a la climática. A lo largo de la Cordillera de los Andes se identifican dos zonas en las cuales el comportamiento de los caudales de los ríos muest...

Calculation of the CAREM reactor with the HUEMUL-PUMA-THERMIT chain of codes

International Nuclear Information System (INIS)

Notari, Carla; Grant, Carlos R.

2000-01-01

The purpose of the work was the evaluation of the the CAREM 25 reactor core, using a chain of codes (HUEMUL-PUMA-THERMIT) different to the one used in the original design (CONDOR-CITVAP-THERMIT). First, we performed a partial validation of the our codes in lattices similar to CAREM and reproduced a benchmark for simulation of gadolinium burnup. The results were considered satisfactory for this stage of the project. Then, we calculated the core along the normal operating equilibrium cycle and in hot and cold shut-down conditions. The main outcome of our evaluation confirms the general behaviour of the reference calculations except in one important point referring to the cold shut down. In this condition, the failure of one single rod of bank number 13 of the shut down system, leaves the core in a supercritical state at the beginning of the cycle and this anomaly persists during almost a third of the overall cycle. A new design of the core is proposed with minor modifications of the reference one, without introducing new types of fuel elements and keeping the same fuel management scheme. This new core fulfills all the design requirements. (author)

The multianalyser system of the three axes neutron spectrometer PUMA: Pilot experiments with the innovative multiplex technique

Energy Technology Data Exchange (ETDEWEB)

Sobolev, Oleg; Hoffmann, Ron; Gibhardt, Holger [Institute for Physical Chemistry, Georg-August-University of Göttingen, Tammannstr. 6, D-37077 Göttingen (Germany); Jünke, Norbert [Forschungs-Neutronenquelle Heinz-Maier-Leibnitz, Technical University of Munich, Lichtenbergstr. 1, D-85748 Garching (Germany); Knorr, Andreas; Meyer, Volker [Institute for Physical Chemistry, Georg-August-University of Göttingen, Tammannstr. 6, D-37077 Göttingen (Germany); Eckold, Götz, E-mail: geckold@gwdg.de [Institute for Physical Chemistry, Georg-August-University of Göttingen, Tammannstr. 6, D-37077 Göttingen (Germany)

2015-02-01

A new type of multiplex technique for three axes neutron spectrometers has been realized and successfully commissioned at the PUMA spectrometer at FRM II. Consisting of eleven analyser-detector channels which can be configured individually, this technique is especially suitable for kinetic experiments where a single excitation spectrum is recorded as a function of time without the need to move the spectrometer. On a time-scale of seconds an entire spectrum can be recorded thus allowing users to monitor changes during fast kinetic processes in single shot experiments without the need for stroboscopic techniques. Moreover, the multianalyser system provides an efficient and rapid tool for mapping excitations in (Q,ω)-space. The results of pilot experiments demonstrate the performance of this new technique and a user-friendly software is presented which assists users during their experiments.

Dualidad y diálogo postcolonial: desmarginalización de la lengua popular y del pensamiento andino en Rosa Cuchillo, de Óscar Colchado Lucio

Directory of Open Access Journals (Sweden)

Víctor Quiroz

2014-06-01

Full Text Available En este artículo examinaremos cómo se inscribe la dualidad, aspecto fundamental de la racionalidad andina, en un texto literario. De este modo, estudiaremos la presencia activa de la dualidad tanto en el plano del contenido (el mundo representado cuanto en el plano de la expresión (el lenguaje y los mecanismos discursivos de Rosa Cuchillo (1997, la novela más importante del escritor peruano Óscar Colchado Lucio. Planteamos que la actualización de la dualidad en este texto contribuye a la desmarginalización y descolonización de la racionalidad andina con el fin de proponerla como un modo de pensamiento alternativo desde el que se pueden replantear los términos del diálogo entre lo occidental y lo andino más allá de las jerarquías coloniales.

Su majestad quiere saber. Información oficial y reformismo borbónico: el mundo andino bajo la mirada de la ilustración

Directory of Open Access Journals (Sweden)

Juan Marchena Fernández

2005-11-01

Full Text Available Estudio dedicado a analizar el proceso de recolección de información burocrática que la Corona española requirió de sus posesiones americanas, durante las últimas décadas del siglo XVIII. La monarquía española demandó información sobre una variedad de aspectos que incluían producción, población, rentas, impuestos, doctrinas, costumbres, etc. El estudio escudriña, de manera específica, las vicisitudes que marcaron el cumplimiento de esta disposición real en el espacio andino. Se analizan las mediaciones sociales, políticas y culturales locales que estuvieron presentes en el proceso de recolección de la información. Por un lado, se subraya la distancia existente entre las premisas reformistas ilustradas que animaban los intereses de la monarquía española, y por otro, las maneras cómo reaccionaron la burocracia colonial y las sociedades andinas locales.

Innovative building automation concept for Pumavision Headquarters. Where Pimas are feeling well; Innovatives Gebaeudeautomationskonzept fuer Pumavision Headquarters. Wo Pumas sich wohl fuehlen sollen

Energy Technology Data Exchange (ETDEWEB)

Habermann, Ralf [IPM Gebaeudeleittechnik GmbH, Feucht bei Nuernberg (Germany); Kerz, Thomas [Siemens-Div. Building Technologies Deutschland, Frankfurt am Main (Germany). Business Unit CPS; Vogel, Helmut [Siemens-Div. Building Technologies Deutschland, Muenchen (Germany). Business Unit CPS Region Bayern

2011-03-15

The sport's and lifestyle company PUMA (Herzogenaurach, Federal Republic of Germany) claims the establishment of the first climate neutral corporate headquarter of its industry. Therefore, the electricity for the new 35,000 m{sup 2} large corporate headquarters exclusively results from renewable energy sources. The conversion of this goal is supported by the interdisciplinary building automation system Desigo from Siemens AG (Munich, Federal Republic of Germany). The basic heating and basic cooling of the main building are performed by a concrete core tempering. A part of the heating and cooling is produced by means of two heat pumps.

La participación política de bolivianos y paraguayos residentes de villas en la ciudad de Buenos Aires: una aproximación desde la lucha por la vivienda

Directory of Open Access Journals (Sweden)

Carla Gallinati

Full Text Available Resumen Este artículo se dedica en analizar la participación política de los migrantes bolivianos y paraguayos que, al lado de la población nacional, desarrollan un proceso de reclamo por la urbanización y por la vivienda digna en las villas de la Ciudad de Buenos Aires. Presentaré parte de la cartografía de discusiones de un grupo específico de residentes de villas que, independiente del origen nacional, compartían problemáticas comunes y reivindicaron ser reconocidos como vecinos de la ciudad y militantes en lucha por la vivienda. La propuesta es poner en foco dos aspectos poco observados por los estudios del campo migratorio: a la centralidad de la escala urbana para el estudio del fenómeno migratorio y b el reclamo como práctica política fundamental en la vida cotidiana (urbana de los migrantes. Es objetivo ofrecer una reflexión sobre las complejas articulaciones entre política, clase y nacionalidad que se abren a partir de un proceso local de puja por el suelo urbano y por el derecho a la ciudad.

Lo que a nadie asusta pero a todos preocupa. Etnografía de los miedos cotidianos en una comunidad del altiplano sur boliviano

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Gil García, Francisco M.

2014-12-01

Full Text Available From the idea that fear is installed in our lives, I analyze the double talk of fears denied and concerns recognized from which the inhabitants of a community in the Bolivian high-plateau explain their daily lives, paying particular attention to the reasons given by adults in the education of children when being in certain environments or forbid them to perform certain actions. So, I will present a spatial distinction among urban settings: the own spaces, secure and recognized —but potentially threatened—, and the territory of the others, which the concurrency of past and present terrible otherness transforms in a frightening geography where things happen, fear scenarios that need to be conspirators and reordered.Partiendo de la idea de que el miedo existe instalado en nuestras vidas, se analiza el doble discurso de miedos negados y preocupaciones reconocidas desde el que los habitantes de una comunidad del altiplano boliviano explican su vida cotidiana, prestando especial atención a las razones esgrimidas por los adultos en la educación de los niños a la hora de prohibirles frecuentar determinados ambientes o realizar en ellos ciertas acciones. Para ello partiré de una distinción espacial dentro del entramado urbano, diferenciando así entre espacios propios, seguros y reconocidos —pero potencialmente amenazados— que, debido a la concurrencia de determinadas alteridades terribles presentes y pretéritas, son sentidos como un territorio de los otros, una geografía atemorizadora donde suceden cosas, escenarios del miedo que necesitan ser conjurados y reordenados.

Análisis de la industria cultural en el pacto de integración sub-regional andino

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Nilo Fernández

2004-01-01

Full Text Available El objetivo general de la presente investigacion fue realizar un analisis de la industria cultural en el pacto de la integracion Sub-regional Andino, destancado el papel fundamental de esta industria como entidad de comunicacion que se construye y se modela a travez de signos culturales que se encuentran en la cotidianidad, en el discurso social y surgidas de realidades entrelazadas, siendo los medios de comunicacion los que hacen percibirlo de otra manera. Las bases teoricas describen como algunos elementos tento del contexto multidimensional de la region andina como elemento socio-juridicos y culturales influyen los aportes de autores tales como: Lorena Rincon, Lucrecia Morales, German Rey, Bernardo Klisberg, Marcelino Bisbal y Nestor Garcia Canclini, entre otros. El tipo de investigacion que se selecciono fue la descriptiva documental; para la cual se utilizo como instrumento de analisis una guia de observacion que permitio ubicar las principales categoria, sub-categorias y las unidades de analisis, de ocho (8 documentos (convenios, acuerdos y declaraciones que constituyeron en una muestra intencional de un total de 16 documentos seleccionados como poblacion inicial que conforman las bases de los pactos que ha suscrito la comunidad Andina de Naciones. Con referencia al analisis e interpretacion de los resultados, se constituyem en hallazgos los planteamientos ubicados en cada uno de los documentos estudiados confirmandose el papel central que juega la industria cultural para la integracion Sub-regional Andina, a pesar de no ser explico en algunos de los documentos.

Conflictos por acceso biotecnológico de los recursos genéticos y conocimientos tradicionales en la región andino-amazónica : los casos de patentes de la maca, el yacón y la sangre de drago

OpenAIRE

Pohlenz de Tavira, Ana

2009-01-01

Este estudio indaga acerca de si la intervención de las actividades biotecnológicas, que aprovecha el conocimiento tradicional, deviene en conflictos socioambientales. De ahí que se revise el por qué ocurren confrontaciones entre las empresas biotecnológicas y las comunidades indígenas. Específicamente, se investigaron tres casos de etnobioprospección en la región andino-amazónica, mediante los cuales se puede entender los modos de operar de la industria biotecnológica, además del sistema de ...

Teoría de las restricciones (TOC) y la mecánica del Throughput Accounting (TA) Una aproximación a un modelo gerencial para toma de decisiones: caso compañía de Cementos Andino S.A.

OpenAIRE

González G., Patricia; Universidad del Valle; Escobar V., John Willmer; Pontificia Universidad Javeriana Cali

2008-01-01

El objetivo de este artículo es explicar a los lectores cómo a partir del modelo de decisión propuesto por la TOC y el TA, los gerentes pueden tomar las mejores decisiones orientadas a maximizar las utilidades del negocio. Para el logro del objetivo propuesto se empleó un caso centrado en la compañía Cementos Andino S.A., en el cual se desarrolló la metodología del TA, cuyos resultados fueron confrontados con los obtenidos a partir del costeo variable, de tal forma que los throughput obtenid...

La transformación del Estado en América Latina: una perspectiva económica desde los países andinos

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Edgard Moncayo Jiménez

2006-01-01

Full Text Available A juicio de muchos analistas, el Estadonación —piedra angular de la organización política del mundo desde la suscripción del Tratado de Wesfalia, en 1968— está experimentando una profunda crisis. En esta visión, el poder efectivo de dicha entidad política se está desbordando en tres direcciones: hacia arriba, por la globalización y la supranacionalización; horizontalmente, por el desmonte del Estado de bienestar, la privatización y la desregulación; y hacia abajo, por la descentralización y la devolución de autonomías a las polis regionales y locales. La acción conjunta de estas tendencias estaría determinando el vaciamiento (hollowing out del Estado-nación, en la medida en que muchas de sus competencias tradicionales se están transfiriendo hacia arriba, a las instituciones internacionales y supranacionales; hacia los lados, al mercado, las empresas privadas y las transnacionales; y hacia abajo, a las entidades de orden subnacional. En este artículo analizaremos el impacto de tales tendencias en los países andinos

Latitudes, el ancho mundo de la investigación social: Bolivianos, paraguayos y argentinos en la obra : Una investigación de la antropóloga Patricia Vargas sobre la relación entre la migración de países limítrofes y el mercado de trabajo en la construcción en el área metropolitana

OpenAIRE

Mendivil, Adrián; Vargas, Patricia

2005-01-01

Latitudes es un ciclo de programas especiales, idea y conducción del periodista Adrián Mendivil, basado en la investigación en ciencias sociales. En esta entrega, se entrevista a la antropóloga Patricia Vargas sobre el impacto de inmigración de países limítrofes en el mercado de trabajo en la construcción en el área metropolitana argentina. Explica el concepto de "etnografía" y su aplicación para comprender la temática: la llegada de bolivianos y paraguayos y su relación con los trabajadores ...

Propuesta de mejoramiento tecnológico de techos verdes para el clima tropical andino

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Alejandro Gómez Cubillos

2018-01-01

Full Text Available La gestión de riesgos por el aumento de la escorrentía superficial en zonas urbanas requiere intervención desde múltiples enfoques, ambientales, sanitarios, sociales y económicas. La infraestructura verde aporta soluciones de creciente interés por sus beneficios ambientales y potencial aprovechamiento económico. Este artículo propone un mejoramiento tecnológi-co para la adaptación de los techos verdes al clima tropical andino, en términos de su com-portamiento hidrológico, para lo cual se desarrolló un montaje experimental con seis módu-los de techos verdes extensivos y un módulo testigo (solo cubierta. El montaje experimental permitió la obtención de datos de 21 eventos de precipitación, modificando la configuración de dos factores experimentales, tipo de planta con seis variaciones y altura de sustrato con tres variaciones y tres eventos más para verificar el efecto de la variación de la pendiente de la cubierta, como tercer factor. Los datos obtenidos se procesaron para el cálculo de las va-riables hidrológicas de interés (precipitación, escorrentía, duración del evento, tiempo ante-rior seco, que expresan las características del evento y los indicadores del comportamiento hidrológico (coeficientes de escorrentía basado en volumen Cv y en el caudal pico Cp y tiem-po de retraso K y su análisis estadístico permitió identificar cuáles factores experimentales tienen o no influencia significativa en dichos indicadores. Finalmente, se desarrollaron herramientas para la simulación de variables e indicadores hidrológicos a partir de series de precipitación externas y su implementación en una herramienta de diseño que seleccione las configuraciones de techos verdes que presenten el mejor comportamiento hidrológico.

Eletrocardiografia em onças-pardas (Puma concolor anestesiadas com sevoflurano ou isoflurano

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A.R. Oliveira

Full Text Available RESUMO O objetivo deste trabalho foi descrever os achados eletrocardiográficos de 11 onças- pardas (Puma concolor. Os animais foram sedados com 0,15mg/kg de detomidina associado a 5mg/kg de cetamina e mantidos anestesiados com sevoflurano (GSEVO, n=6 ou isoflurano (GISO, n=5. A frequência cardíaca foi de 95 ± 13bpm. As alterações observadas nos animais no GSEVO foram: atrial standtill com condução ventricular, episódios isolados de contração ventricular prematura, bloqueio atrioventricular de primeiro grau, diminuição da amplitude do complexo QRS, onda S profunda e aumento da amplitude da onda T. No grupo GISO, observou-se bloqueio de ramo direito do feixe de His, bloqueio atrioventricular de primeiro grau e aumento da amplitude da onda T. Arritmias não puderam ser associadas ao uso dos anestésicos inalatórios devido à não sensibilização do miocárdio às catecolaminas. Achados como o BAV de primeiro grau pode ter ocorrido devido ao uso de agonistas α-2 adrenérgicos. Este estudo aumentou o conhecimento sobre as alterações eletrocardiográficas em onças-pardas anestesiadas, entretanto mais estudos são necessários para correlacionar estes achados ao uso de agentes anestésicos.

Prior Puma Lentivirus Infection Modifies Early Immune Responses and Attenuates Feline Immunodeficiency Virus Infection in Cats

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Wendy S. Sprague

2018-04-01

Full Text Available We previously showed that cats that were infected with non-pathogenic Puma lentivirus (PLV and then infected with pathogenic feline immunodeficiency virus (FIV (co-infection with the host adapted/pathogenic virus had delayed FIV proviral and RNA viral loads in blood, with viral set-points that were lower than cats infected solely with FIV. This difference was associated with global CD4+ T cell preservation, greater interferon gamma (IFN-γ mRNA expression, and no cytotoxic T lymphocyte responses in co-infected cats relative to cats with a single FIV infection. In this study, we reinforced previous observations that prior exposure to an apathogenic lentivirus infection can diminish the effects of acute infection with a second, more virulent, viral exposure. In addition, we investigated whether the viral load differences that were observed between PLV/FIV and FIV infected cats were associated with different immunocyte phenotypes and cytokines. We found that the immune landscape at the time of FIV infection influences the infection outcome. The novel findings in this study advance our knowledge about early immune correlates and documents an immune state that is associated with PLV/FIV co-infection that has positive outcomes for lentiviral diseases.

Cadenas productivas promisorias para la seguridad alimentaria e inclusión económica en familias pobres rurales : caso del proyecto Desarrollo sostenible de granos andinos y papas nativas en comunidades rurales altoandinas de la región Ayacucho implementado por CARE Perú 2009-2011

OpenAIRE

Nishikawa Menacho, Julio

2016-01-01

En la perspectiva de aportar en el desarrollo de políticas de inclusión social y económica, basada en evidencias, se ha desarrollado el presente trabajo de investigación cualitativa tomando como base la experiencia desarrollada por CARE PERU a través del proyecto “Desarrollo Sostenible de Granos Andinos y Papas Nativas en Comunidades Rurales Altoandinas” en el Departamento de Ayacucho. El objetivo central de la investigación fue identificar los principales factores de éxito que han contri...

Democracia paritaria en Latinoamérica: la situación de jure y de facto de la participación política de las mujeres en el contexto boliviano

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Óscar Gonzalo Barrientos Jiménez

2017-12-01

Full Text Available El contexto histórico del desarrollo de los derechos políticos de las mujeres refleja una constante discriminación a favor del género masculino, por ello, y en buena medida gracias a una serie de conquistas significativas de las mismas mujeres, se van adoptando diversos instrumentos internacionales específicos de protección que permitan lograr cierta igualdad de oportunidades en derechos de participación política. En el caso del contexto boliviano, en el marco de la Constitución Política del Estado y de diferentes leyes de desarrollo constitucional, se ha logrado consolidar a Bolivia como el único país de América Latina en lograr resultados de paridad en todos los niveles estatales. No obstante, y sin perder objetividad, el trabajo refleja también la sistemática violación de derechos de participación política de autoridades municipales electas. A continuación se analiza la aplicación de la primera ley específica de acoso y violencia política en Latinoamérica. Las conclusiones muestran que la construcción de una democracia paritaria plena contribuye a la legitimidad democrática, el buen gobierno y el desarrollo sostenible de cualquier país.

Area Handbook Series: Bolivia: A Country Study

Science.gov (United States)

1989-12-01

sightseeing on the national railroad, and the Indian cultures. The government’s Boliv- ian Institute of Tourism (Instituto Boliviano de Turismo ...Colegio de Mexico, 1979. Zavaleta Mercado, Ren6 (ed.). Bolivia, hoy. Mexico City: Siglo Veintiuno Editores, 1983. -. Las masas en Novienbre. La Paz...123 Bel6im (Brazil), 148 Bolivian Institute of Tourism (Instituto Brz6 Hum~ez, Manuel Isidoro, xxviis, Boliviano de Turismo ), 149 20, 164 Bolivian

RELACIÓN ENTRE LA BIOMASA Y ALGUNAS CARACTERÍSTICAS MORFOLÓGICAS DE LAS BROMELIAS FITOTELMATAS DE UN BOSQUE ALTO ANDINO COLOMBIANO

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Isaza Carolina

2009-06-01

Full Text Available Se evaluaron algunas características morfológicas para seis especies de bromelias fitotelmata (Guzmania gloriosa, Racinaea tetrantha, Tillandsia biflora, T. complanata, T. fendleri y T. turneri con el fin de establecer cuales características podrían utilizarse como estimadores indirectos de la biomasa total de la planta. El estudio se realizó en un bosque alto andino de la Sabana de Bogotá, Colombia, ubicado a 2900 m de altitud. Para cada especie se recolectaron entre 32 y 64 individuos en diferentes estadios de crecimiento, a cada uno de los cuales se le registró: 1 el número de hojas por roseta; 2 el perímetro de la base de la roseta; 3 la cobertura de la planta; 4 el largo de la lámina foliar; 5 la altura de la roseta; y 6 la biomasa total. Los resultados de la prueba Wilcoxon muestran que la cobertura fue la variable que más se relacionó con la biomasa. Una prueba de ajuste de curva mostró que la línea recta es la que más explica la relación entre la cobertura y la biomasa, permitiendo hacer estimaciones a partir de la ecuación sin ser necesario un muestreo destructivo.

Circuitos de la economía urbana en la ciudad de Buenos Aires: el comercio étnico de la colectividad boliviana en el barrio de Liniers

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Mauro Escobar Basavilbaso

2012-12-01

Full Text Available Las divisiones territoriales del trabajo coexistentes en las ciudades pueden ser estudiadas como un circuito superior y un circuito inferior de la economía. El objetivo de este trabajo es comprender la convivencia de dichos circuitos en el barrio de Liniers (Ciudad Autónoma de Buenos Aires para analizar los rasgos que toma el circuito inferior y en particular, el comercio étnico boliviano. Las características del medio construido de Liniers y su situación de encrucijada y nudo del transporte de pasajeros lo convierten en un distrito comercial privilegiado con un enorme y fluido mercado. Sobresale allí el circuito inferior y en particular el comercio étnico boliviano. Para tal fin hemos utilizado estrategias cualitativas, tales como recorridos de visu, entrevistas a comerciantes argentinos y bolivianos.

Características de la avifauna en un gradiente altitudinal de un bosque nublado andino en La Paz, Bolivia

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Omar Martínez

2013-04-01

Full Text Available El presente trabajo analiza la diversidad y composición de la avifauna en tres localidades ubicadas dentro del Parque Nacional y Área Natural de Manejo Integrado de Cotapata, La Paz, Bolivia. Las tres localidades se distribuyeron en gradiente altitudinal y tres tipos de bosques húmedos andinos (ceja de monte a 3170 m, bosque nublado a 2620 m y bosque nublado secundario a 1850 m de la zona Yungas. Se realizó un esfuerzo total de 3286 horas-red niebla, 324 horas de caminatas y 216 horas de conteos por puntos en los tres lugares de estudio. Un total de 220 especies fueron registradas, la mayoría capturadas en redes (100 spp., 45%. Veinticinco familias fueron representadas en las capturas por redes y 42 mediante los censos. Tyrannidae y Thraupidae fueron las más representativas mediante ambos métodos. Las curvas acumulativas de especies fueron similares en todos los sitios. La riqueza de especies para la ceja de monte, bosque nublado y bosque secundario a partir de las capturas y censos fueron de 44, 40, 44 especies y 69, 57, 86 especies, respectivamente. Un total de 16 especies de rango restringido fueron registradas (p.e. Odontophorus balliviani, Andigena cucullata. La diversidad para la ceja de monte fue H´= 1,41; para el bosque nublado (H´= 0,98 y el bosque nublado secundario (H´= 0,96. La diversidad beta fue 0,74 basada en datos de capturas con redes y 0,79 basada en datos de censos en las tres alturas.

Both p53-PUMA/NOXA-Bax-mitochondrion and p53-p21cip1 pathways are involved in the CDglyTK-mediated tumor cell suppression

International Nuclear Information System (INIS)

Yu, Zhendong; Wang, Hao; Zhang, Libin; Tang, Aifa; Zhai, Qinna; Wen, Jianxiang; Yao, Li; Li, Pengfei

2009-01-01

CDglyTK fusion suicide gene has been well characterized to effectively kill tumor cells. However, the exact mechanism and downstream target genes are not fully understood. In our study, we found that CDglyTK/prodrug treatment works more efficiently in p53 wild-type (HONE1) cells than in p53 mutant (CNE1) cells. We then used adenovirus-mediated gene delivery system to either knockdown or overexpress p53 and its target genes in these cells. Consistent results showed that both p53-PUMA/NOXA/Bcl2-Bax and p53-p21 pathways contribute to the CDglyTK induced tumor cell suppression. Our work for the first time addressed the role of p53 related genes in the CDglyTK/prodrug system.

Both p53-PUMA/NOXA-Bax-mitochondrion and p53-p21cip1 pathways are involved in the CDglyTK-mediated tumor cell suppression

Energy Technology Data Exchange (ETDEWEB)

Yu, Zhendong, E-mail: zdyu@hotmail.com [Department of Clinical laboratory, Peking University Shenzhen Hospital, Guangdong (China); Wang, Hao [Department of pathology, The Chinese University of Hong Kong, Hong Kong (China); Zhang, Libin; Tang, Aifa; Zhai, Qinna; Wen, Jianxiang; Yao, Li [Department of Clinical laboratory, Peking University Shenzhen Hospital, Guangdong (China); Li, Pengfei, E-mail: lipengfei@cuhk.edu.hk [Department of pathology, The Chinese University of Hong Kong, Hong Kong (China)

2009-09-04

CDglyTK fusion suicide gene has been well characterized to effectively kill tumor cells. However, the exact mechanism and downstream target genes are not fully understood. In our study, we found that CDglyTK/prodrug treatment works more efficiently in p53 wild-type (HONE1) cells than in p53 mutant (CNE1) cells. We then used adenovirus-mediated gene delivery system to either knockdown or overexpress p53 and its target genes in these cells. Consistent results showed that both p53-PUMA/NOXA/Bcl2-Bax and p53-p21 pathways contribute to the CDglyTK induced tumor cell suppression. Our work for the first time addressed the role of p53 related genes in the CDglyTK/prodrug system.

Estructura genética y simulaciones de máxima verosimilitud y Estadística Bayesiana aplicada a la conservación genética del Oso andino (Tremarctos ornatus en Venezuela, Colombia, Ecuador y Bolivia

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M. Ruiz-García

2001-07-01

Full Text Available Se analizaron 115 muestras de oso andino procedentes de Venezuela, Colombia, Ecuador yBolivia mediante 5 microsatélites (G1A, G1D, G10B, G10C, G10M, G10P, G10X, UarMu 50,UarMu, 59. Se detectó: (1 No existencia de equilibrio Hardy-Weinberg en ninguna de laspoblaciones analizadas en cada uno de los países, lo que evidencia la existencia de efectoWahlund. (2 Los niveles de variabilidad genética fueron bajos (H=0.40, población total.Alarmantemente bajo fue el nivel de heterocigocidad en la población de Ecuador (H=0.27. (3Los niveles de flujo génico resultaron bajísimos (Nm=0.2-0.3.

Géneros y formatos para la televisión digital. Análisis en los países andinos

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Abel Suing

2016-05-01

Full Text Available El propósito de la investigación es analizar los formatos de televisión vigentes en la transición hacia la televisión digital terrestre en los países andinos e identificar alternativas para la televisión local. La investigación se justifica en razón del apagón analógico entre el 2018 y 2020. La metodología es cualitativa y cuantitativa; los instrumentos son análisis de contenidos y entrevistas semiestructuradas. Los resultados permiten concluir que los contenidos de producción nacional están vinculados con la actualidad. Los elementos que influyen en la creación de contenidos están relacionados con factores de identidad, recursos económicos, talento humano y narrativas. La hibridación de formatos que promuevan la cultura es una opción para las estaciones locales. The purpose of the research is to analyze the current television formats in the transition to digital terrestrial television in the Andean countries, and to identify alternatives for the local television. The research is justified in view of the analog blackout that will occur between 2018 and 2020. The methodology is both qualitative and quantitative; the instruments are content analyses and semi-structured interviews. The results allow concluding that the local production contents are linked to current events. The elements that influence the creation of contents are related to factors of identity, economic resources, human talent and narratives. The hybridization of formats promoting culture is an option for the local stations.

Tras las huellas de los Ñanaigua: de tapii, tapiete y otros salvajes en el Chaco boliviano

Directory of Open Access Journals (Sweden)

2004-01-01

Full Text Available Parmi les noms de peuples et d’ethnies qui pullulent dans les chroniques coloniales, ceux de Tapii et Tapiete ont mis beaucoup d’auteurs à l’épreuve et ont été qualifiés de véritable “énigme ethnografique”. Ils ont donné lieu, en particulier, à de nombreuses confusions dans la littérature postérieure, faute de prêter attention à leur sens original et générique : “esclaves”, ou “vrais esclaves”. Ainsi, les étiquettes de Tapii et Tapiete ont pu désigner différentes ethnies selon les lieux et les époques. L’article tente d’éclaircir le panorama dans le cas du Chaco bolivien, tout en introduisant un troisième terme générique qui est celui de Ñanaigua ou “sauvages”, et en présentant des données historiques inédites sur les différentes ethnies ainsi appelées au XIXe siècle. Entre los nombres de etnias y pueblos que pululan en las crónicas coloniales, los de tapii y tapiete han puesto a prueba muchos autores y fueron calificados de verdadero “enigma etnográfico”. Han dado lugar, en particular, a muchas confusiones en la literatura posterior, principalmente por no prestar atención a su sentido original y genérico: “esclavos” o “verdaderos esclavos”. Así, las etiquetas de tapii y tapiete han podido designar a diferentes etnias según los lugares y las épocas. El artículo intenta aclarar el panorama en el caso del Chaco boliviano, introduciendo un tercer término genérico que es el de ñanaigua o “salvaje”, y aportando datos históricos inéditos sobre las diferentes etnias así designadas en el siglo XIX. Among the many ethnonyms that proliferate throughout the colonial records, those of tapii and tapiete have challenged a number of scholars, and have even been deemed an “ethnographic enigma.” Largely due to ignorance of their original and generic meaning -“slaves” and “true slaves”- both have given rise to several confusions in subsequent literature. In fact, the labels tapii and tapiete

Diet of margay, Leopardus wiedii, and jaguarundi, Puma yagouaroundi, (Carnivora: Felidae in Atlantic Rainforest, Brazil

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Rita de Cassia Bianchi

2011-02-01

Full Text Available This study identifies the food habits of the margay, Leopardus wiedii (Schinz, 1821, and the jaguarundi, Puma yagouaroundi (É. Geoffroy Saint-Hilare, 1803, in the Vale do Rio Doce Natural Reserve and in the Sooretama Biological Reserve, Espírito Santo, Brazil. We determined the diet of both species by the analysis of scats. Fecal samples were collected from April 1995 to September 2000 and identified based on the presence of hairs that were ingested during self-grooming. Scats were oven-dried and washed on a sieve, and the screened material was identified using a reference collection. Of the 59 fecal samples examined, 30 were confirmed to be from the margay and nine of them from the jaguarundi. Mammals were the most consumed items in the diet of the margay, occurring in 77% of the fecal samples, followed by birds (53% and reptiles (20%. Among the mammals consumed, marsupials (Didelphimorphia were the most common item (66%. In the diet of the jaguarundi, birds were the most consumed items and occurred in 55% of the fecal samples; mammals and reptiles occurred in 41% and in 17% of the fecal samples, respectively. From this work we conclude that the margay and jaguarundi fed mainly upon small vertebrates in the Vale do Rio Doce Natural Reserve and in the Sooretama Biological Reserve. Although sample sizes are therefore insufficient for quantitative comparisons, margays prey more frequently upon arboricolous mammals than jaguarundis, which in turn prey more frequently upon birds and reptiles than margays. This seems to reflect a larger pattern throughout their geographic range

Productores de una educación inclusiva: Fronteras ideográficas, demográficas, cartográficas y biográficas que, desde las prácticas formativas, delimitan la gestión de una educación inclusiva-diversa en la Institución Educativa Andino de San Lorenzo, del municipio de Bolívar (Cauca)

OpenAIRE

Muñoz Cerón, Miguel Angel; López Silva, Franciny Guillermo; Rivera Joaquí, Silvio Tulio; Valencia González, Gloria Clemencia

2015-01-01

Tesis (Maestría en Educación desde la Diversidad). Universidad de Manizales. Facultad de Ciencias Sociales y Humanas-Instituto Pedagógico, 2015 El presente documento, denominado Productores de una educación inclusiva. Fronteras ideográficas, demográficas, cartográficas y biográficas que, desde las prácticas formativas, delimitan la gestión de una educación inclusiva-diversa en la Institución Educativa Andino de San Lorenzo, del municipio de Bolívar (Cauca), presenta los hallazgos de un pr...

La televisión social en los países andinos. Análisis de los medios sociales en informativos y magazines

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Abel Suing

2015-12-01

Full Text Available Los países andinos transitan hacia la televisión digital al mismo tiempo en que se consolidan los medios sociales que otorgan a la audiencia la capacidad de interactuar en tiempo real, ello deriva en interrogantes como ¿existe integración de los medios sociales en la televisión?, ¿la audiencia participa en la definición de la televisión digital? y ¿estamos frente a la televisión social? La investigación pretende responder a las preguntas señaladas mediante el estudio de los programas de noticias y magazines de las estaciones de televisión líderes del área andina, en razón de que sus contenidos se emiten en tiempo real cuando se generaría el mayor interés de la audiencia. La metodología empleada es cuantitativa y cualitativa a partir del análisis de cuentas en Facebook y Twitter de las estaciones. Las hipótesis son que la televisión social gana aceptación en los países del área andina y que los canales de televisión no explotan los medios sociales. Se concluye que las estaciones privadas muestran más actividad que las públicas, que existe diferencia entre los informativos y el entretenimiento en seguidores y actividad en la red y que estamos en el inicio de la televisión social pero demanda más esfuerzos para integrar pantallas y medios sociales.

Development of a simple screening tool for opportunistic COPD case finding in primary care in Latin America: The PUMA study.

Science.gov (United States)

López Varela, Maria Victorina; Montes de Oca, Maria; Rey, Alejandra; Casas, Alejandro; Stirbulov, Roberto; Di Boscio, Valentina

2016-10-01

Opportunistic chronic obstructive pulmonary disease (COPD) case finding approaches for high-risk individuals with or without symptoms is a feasible option for disease identification. PUMA is an opportunistic case finding study conducted in primary care setting of Argentina, Colombia, Venezuela and Uruguay. The objectives were to measure COPD prevalence in an at-risk population visiting primary care for any reason, to assess the yield of this opportunistic approach and the accuracy of a score developed to detect COPD. Subjects attending routine primary care visits, ≥40 years of age, current or former smokers or exposed to biomass smoke, completed a questionnaire and performed spirometry. COPD was defined as post-bronchodilator (post-BD) forced expiratory volume in 1 s (FEV1 )/forced vital capacity (FVC) 50 years, heavy smokers (>30 pack-years), with dyspnoea, and having prior spirometry. A simple score and a weighted score constructed using the following predictive factors: gender, age, pack-years smoking, dyspnoea, sputum, cough and spirometry, had a mean accuracy for detecting COPD (post-BD FEV1 /FVC tool to select subjects for spirometry in primary care. © 2016 Asian Pacific Society of Respirology.

CARACTERIZACIÓN FÍSIOGRÁFICA DE LA PUNA DE SAJAMA, CORDILLERA OCCIDENTAL DE LOS ANDES (BOLIVIA

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Fernando Javier Santa Cecilia Mateos

2015-01-01

Full Text Available Este artículo aproxima a la realidad física de la cordillera Occidental de los Andes. Un espacio geográfico donde los caracteres geológicos relacionados con el vulcanismo adquieren una relevancia especial en la configuración del paisaje andino. Los nevados y llanuras intermedias o altiplanos, son los dos elementos que constituyen la imagen de la puna andina, un territorio situado por encima de los 4.000 metros, ámbito intermedio entre los valles húmedos o yungas y las más altas cumbres de los Andes. A la singularidad volcánica habría que añadir la relacionada con el modelado glaciar, los aspectos hidrográficos y la biogeografia en esta área. El artículo toma como ejemplo de estudio la puna de Sajama en eldepartamento de Oruro, en la frontera boliviano-chilena.Abstract. This article approaches the physical reality of the Western Cordillera of the Andes. A geographical space where characters related geological volcanism are of particular importance in shaping the landscape Andean. The intermediate plains or mountains and plateaus, are the two elements that make up the image of the Andean puna, an area located above 4,000 meters, the middle ground between Yungas wet valley and the highest peaks of the Andes. A volcanic uniqueness should add that related to glacier modeling, hydrographic aspects and biogeography in this area. The article uses the example of the highlands of Sajama study in thedepartment of Oruro in Bolivian-Chilean border.

“Los embrujos secretos del trópico”. Frontera amazónica y producción del espacio estatal en la obra cinematográfica de Jorge Ruiz

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Roberto Pareja

2014-11-01

Full Text Available Este artículo estudia la obra cinematográfica de Jorge Ruiz utilizando la teoría socio-espacial de Henri Lefebvre. Argumenta que sus documentales, películas etnográficas y noticieros para el cine constituyen una totalidad discursiva que presenta estéticamente la producción del espacio estatal boliviano durante el siglo XX. A partir de una retórica audiovisual que juega con nociones de verticalidad, horizontalidad y centralidad, la obra de Ruiz posiciona el espacio andino como el eje de la modernización estatal y sitúa  a la cuenca amazónica en los márgenes del estado. Concluye que hacer visible la región amazónica en el discurso de la nación tuvo como efecto el desplazamiento de los antagonismos de clase en favor del conflicto entre centro y regiones.This article studies the cinematography of Jorge Ruiz making use of the socio-spatial theory of Henri Lefebvre. It argues that his documentaries, ethnographic films and newsreels for the cinema constitute a discursive totality that presents aesthetically the production of the Bolivian state space during the twentieth century. From an audiovisual rhetoric that plays with notions of verticality, horizontality and centrality, Ruiz’s work locates Andean space as the focal point of state modernization and situates the Amazon basin at the margins of the state. It concludes that in making the Amazon region visible in the nation’s discourse this had the effect of displacing class antagonisms in favor of the conflict between center and regions.

Comparison between a finite difference model (PUMA) and a finite element model (DELFIN) for simulation of the reactor of the atomic power plant of Atucha I; Comparacion entre un modelo de diferencias finitas (PUMA) y uno de elementos finitos (DELFIN) para la simulacion del reactor de la CNA-I (central nuclear Atucha-I)

Energy Technology Data Exchange (ETDEWEB)

Grant, C R [Comision Nacional de Energia Atomica, San Martin (Argentina). Unidad de Actividad Reactores y Centrales Nucleares

1997-12-31

The reactor code PUMA, developed in CNEA, simulates nuclear reactors discretizing space in finite difference elements. Core representation is performed by means a cylindrical mesh, but the reactor channels are arranged in an hexagonal lattice. That is why a mapping using volume intersections must be used. This spatial treatment is the reason of an overestimation of the control rod reactivity values, which must be adjusted modifying the incremental cross sections. Also, a not very good treatment of the continuity conditions between core and reflector leads to an overestimation of channel power of the peripherical fuel elements between 5 to 8 per cent. Another code, DELFIN, developed also in CNEA, treats the spatial discretization using heterogeneous finite elements, allowing a correct treatment of the continuity of fluxes and current among elements and a more realistic representation of the hexagonal lattice of the reactor. A comparison between results obtained using both methods in done in this paper. (author). 4 refs., 3 figs.

Evaluación ambiental del proceso de urbanización de las cuencas del piedemonte andino de Santiago de Chile

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Hugo Romero

2005-12-01

Full Text Available Las cuencas son complejos sistemas ambientales en que se desarrollan procesos geomorfológicos, hidrológicos, climáticos y ecológicos, que son impactados por la urbanización. En este trabajo se estudian seis cuencas del piedemonte andino de la ciudad de Santiago que se encuentran en diferentes fases del proceso de urbanización, variando entre Macul-San Ramón, en donde casi el 40% de su superficie ha sido incorporada a la ciudad, y Pirque, que mantiene aún sus características agrícolas y rurales. Empleando Sistemas de Información Geográfica, se analiza el impacto de la urbanización sobre indicadores ambientales, tales como productividad vegetal, biomasa, humedad en el suelo y temperaturas superficiales de los territorios ocupados por las cuencas. Las Áreas Totales de Impermeabilización, los Coeficientes de Escorrentía y las Áreas Sensitivas Ambientales, permiten estimar el estado de las cuencas y su contribución a la salud ambiental de la ciudad de SantiagoWatersheds are complex environmental systems, where geomorphologic, hydrologic, climatic and ecological processes take place, and which are severely impacted by urbanisation. In this paper, six Santiago Andean piedmont watersheds have been researched, according with the degree of urbanisation that they reach, which varies between Macul-San Ramón, where about 40% of their land covers has been already urbanised, until Pirque, where agricultural and rural features are still dominants. Using geographical information systems, the impact of urbanization on several ecological indicators, such as vegetative productivity, biomass, soil moisture and surface temperature are analysed. Total Imperviousness Areas, Runoff Coefficients and Environmentally Sensitive Areas allow the estimation of the state of the watersheds ant their contribution to the environmental health of Santiago city

Nuevas evidencias de la presencia del Oso Andino (Tremarctos ornatus en las Yungas de Puno, el registro más austral de Perú

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Gisella Márquez

2011-05-01

Full Text Available El oso de anteojos Tremarctos ornatus es el único representante de la familia Ursidae en Suramérica. La población más grande y de distribución continua del oso andino en el Perú, se localiza en la ladera oriental de la cordillera oriental, incluyendo al departamento de Puno, donde casi todos los registros de esta especie provienen solamente de encuestas. Se describe aquí dos registros indirectos de la presencia del oso en el departamento de Puno, obtenidos en agosto del año 2009. El primer registro corresponde a una feca, con semillas perteneciente a la familia Lauraceae, encontrada en Yanacocha; y el segundo registro corresponde a unas marcas de garras del oso hallado en Challohuma. Este último representa el registro más austral con- firmado para la distribución del oso de anteojos en el Perú. Nuestros registros evidencian una continuidad en la distribución de esta especie en la vertiente oriental de la cordillera andina, desde el sur del Perú hasta el noroeste de Bolivia. Estos registros se hallan también muy próximos al Parque Nacional Bahuaja Sonene (PNBS, uno de los corredores de conservación más importantes en el mundo, y muestran la importancia de establecer estrategias de conservación tanto dentro como fuera de la zona de amortiguamiento del PNBS.

Pride diaries: sex, brain size and sociality in the African lion (Panthera leo) and cougar (Puma concolor).

Science.gov (United States)

Arsznov, Bradley M; Sakai, Sharleen T

2012-01-01

The purpose of this study was to examine if differences in social life histories correspond to intraspecific variation in total or regional brain volumes in the African lion (Panthera leo) and cougar (Puma concolor). African lions live in gregarious prides usually consisting of related adult females, their dependent offspring, and a coalition of immigrant males. Upon reaching maturity, male lions enter a nomadic and often, solitary phase in their lives, whereas females are mainly philopatric and highly social throughout their lives. In contrast, the social life history does not differ between male and female cougars; both are solitary. Three-dimensional virtual endocasts were created using computed tomography from the skulls of 14 adult African lions (8 male, 6 female) and 14 cougars (7 male, 7 female). Endocranial volume and basal skull length were highly correlated in African lions (r = 0.59, p African lions or cougars. However, relative anterior cerebrum volume comprised primarily of frontal cortex and surface area was significantly greater in female African lions than males, while relative posterior cerebrum volume and surface area was greater in males than females. These differences were specific to the neocortex and were not found in the solitary cougar, suggesting that social life history is linked to sex-specific neocortical patterns in these species. We further hypothesize that increased frontal cortical volume in female lions is related to the need for greater inhibitory control in the presence of a dominant male aggressor. Copyright © 2012 S. Karger AG, Basel.

Ecologia e conservação da onça parda (Puma concolor Linnaeus, 1771) no Parque Estadual do Rio Doce (PERD) e entorno do Parque Estadual da Serra do Brigadeiro (PESB), Minas Gerais

OpenAIRE

Barros, João Bosco Gonçalves de

2009-01-01

Com a crescente fragmentação da Mata Atlântica, maior bioma brasileiro ameaçado, o entendimento do comportamento de espécies-chave de grande porte como a onça parda (Puma concolor), torna-se importante para elaboração de estratégias de conservação. Neste sentido, os objetivos deste estudo foram avaliar o status de conservação da espécie e de outros felinos de maior porte na região sul do Parque Estadual do Rio Doce (PERD), Marliéria-MG; acompanhamento por técnica de rádio telemetria, de exemp...

Evaluation of cardiopulmonary parameters and recovery from anesthesia in cougars (Puma concolor anesthetized with detomidine/ketamine and isoflurane or sevoflurane

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Verônica B. Albuquerque

2016-01-01

Full Text Available Abstract: The aim of this study was to assess the cardiopulmonary effects, the onset time after the administration of a detomidine/ketamine combination, and the recovery from anesthesia of cougars (Puma concolor anesthetized with detomidine/ketamine and isoflurane or sevoflurane for abdominal ultrasound imaging. Fourteen animals were randomly allocated into two experimental groups: GISO (n=7 and GSEVO (n=7. Chemical restraint was performed using 0.15mg/kg detomidine combined with 5mg/kg ketamine intramuscularly; anesthesia induction was achieved using 2mg/kg propofol intravenously and maintenance with isoflurane (GISO or sevoflurane (GSEVO. The following parameters were assessed: heart rate, respiratory rate, systolic and diastolic arterial blood pressure, mean arterial blood pressure, oxyhemoglobin saturation, rectal temperature, central venous pressure, and end-tidal carbon dioxide. The time to sternal recumbency (TSR and time to standing position (TSP were also determined. There was not statistically significant difference for the cardiopulmonary variables or TSP whereas TSR was significantly shorter in GSEVO. The time to onset of anesthesia was 11.1±1.2 minutes and 11.3±1.8 minutes for GISO and GSEVO, respectively. The anesthesia of cougars with detomidine/ketamine and isoflurane or sevoflurane was conducted with safety, cardiopulmonary stability, and increased time to sternal recumbency in the GISO group.

Migração boliviana e doença de Chagas: limites na atuação do Sistema Único de Saúde brasileiro (SUS

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Nivaldo Carneiro Junior

2017-06-01

Full Text Available Migrações acarretam mudanças nos perfis epidemiológicos, impactando sistemas de saúde dos países receptores. O Brasil atrai imigrantes que se inserem precariamente nas metrópoles. Na Bolívia, a doença de Chagas é endêmica, fato relevante para o SUS brasileiro.O texto analisa a atuação e os limites dos profissionais de saúde no atendimento aos bolivianos no SUS, enfocando a doença de Chagas, por meio de entrevistas aplicadas nos serviços primário, secundário e terciário na região central da cidade de São Paulo, principal destino dos imigrantes bolivianos. As precárias condições de vida dos bolivianos caracterizam iniquidades em saúde. Idioma e cultura limitam a compreensão sobre o cuidado. Constata-se desconhecimento da clínica e epidemiologia da doença de Chagas entre os profissionais que atendem esses imigrantes. Faz-se necessária a revisão de estratégias assistenciais e de controle da doença de Chagas.

SURGICAL MANAGEMENT OF APPENDICULAR LONG-BONE FRACTURES IN FREE-RANGING FLORIDA PANTHERS ( PUMA CONCOLOR CORYI): SIX CASES (2000-2014).

Science.gov (United States)

Au Yong, Jo Anne; Lewis, Daniel D; Citino, Scott B; Cunningham, Mark W; Cross, Alan R; Farese, James P; Pablo, Luisito S

2018-03-01

The clinical outcomes of six free-ranging Florida panthers ( Puma concolor coryi) that underwent surgical stabilization of appendicular long-bone fractures (three femoral fractures, one tibial and one tibial and fibular fracture and two radial and ulnar fractures) were evaluated. These panthers presented to the University of Florida from 2000-2014. Estimated age of the panthers ranged from 0.5 to 4.5 yr, and weights ranged from 22 to 65 kg. Causes of injuries were vehicular collision ( n = 4) and capture related ( n = 2). All panthers underwent open reduction and fracture stabilization. Fixation failure necessitated three subsequent surgeries in one panther. Five panthers survived the immediate postoperative period, and all of these panthers' fractures obtained radiographic union (range, 8-36 [mean, 22] wk). The five surviving panthers underwent convalescence for 7-14 mo at White Oak Conservation Center before being released back into the wild; however, one panther was killed when hit by a car 3 days after release. The remaining four panthers were tracked for up to 106 mo in the wild and successfully integrated back into the native population. Surgical stabilization of appendicular long-bone fractures in free-ranging Florida panthers can be successful, but must take into account the stress that a large, undomesticated felid will place on the stabilized limb during convalescence as well as the difficulties involved in rehabilitating a wild panther in captivity.

Hábito alimentar e interferência antrópica na atividade de marcação territorial do Puma concolor e Leopardus pardalis (Carnivora: Felidae e outros carnívoros na Estação Ecológica de Juréia-Itatins, São Paulo, Brasil Food habits and anthropic interference on the territorial marking activity of Puma concolor and Leopardus pardalis (Carnivora: Felidae and other carnivores in the Juréia-Itatins Ecological Station, São Paulo, Brazil

Directory of Open Access Journals (Sweden)

Rogério Martins

2008-09-01

Full Text Available Os hábitos alimentares da onça-parda, jaguatirica e outros carnívoros foram estudados na Juréia (80.000 ha, um dos maiores remanescentes de Mata Atlântica do estado de São Paulo. O estudo foi baseado na análise de fezes encontradas durante um período de amostragem de 15 meses e 415 km percorridos. A diversidade de presas encontradas nas fezes foi alta para ambos os felinos, tendo como presas mais importantes da onça-parda em freqüência de ocorrência e biomassa, o cateto e o tatu-de-rabo-mole, e marsupiais na dieta da jaguatirica. Maior freqüência de fezes de carnívoros foi encontrada distante das casas de moradores tradicionais, sugerindo um comportamento territorial evitando a proximidade da presença humana.Food habits of puma, ocelot and other carnivores were studied in Juréia (80.000 ha, one of the largest remnants of Atlantic forest of the state of São Paulo. The study was based on the analysis of scats found during a sampling period of 15 months and 415 km traversed. The diversity of prey found was high for both felines, with higher frequency and estimated biomass of collared peccary and the greater naked-tailed armadillo in the diet of the puma, and marsupials in the diet of the ocelot. The highest frequency of carnivore scats was found distant from traditional households, suggesting avoidance behavior towards human presence.

Comparison between a finite difference model (PUMA) and a finite element model (DELFIN) for simulation of the reactor of the atomic power plant of Atucha I

International Nuclear Information System (INIS)

Grant, C.R.

1996-01-01

The reactor code PUMA, developed in CNEA, simulates nuclear reactors discretizing space in finite difference elements. Core representation is performed by means a cylindrical mesh, but the reactor channels are arranged in an hexagonal lattice. That is why a mapping using volume intersections must be used. This spatial treatment is the reason of an overestimation of the control rod reactivity values, which must be adjusted modifying the incremental cross sections. Also, a not very good treatment of the continuity conditions between core and reflector leads to an overestimation of channel power of the peripherical fuel elements between 5 to 8 per cent. Another code, DELFIN, developed also in CNEA, treats the spatial discretization using heterogeneous finite elements, allowing a correct treatment of the continuity of fluxes and current among elements and a more realistic representation of the hexagonal lattice of the reactor. A comparison between results obtained using both methods in done in this paper. (author). 4 refs., 3 figs

Algunas reflexiones desde la acuarela de Mario Conde

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Pamela Romano

2012-11-01

Full Text Available This brief reflection on the work of Mario Conde starts paying attention to the special relationship the artist has with the watercolor technique, deploying from that relationship a copy-based ethics. From that materiality Conde builds his response to the postmodern moment in which art in general, and particularly Bolivian art, is been developed given its current social conditions. The ethics of the copy is explored especially in two of his works: "Exterminator Angel" where  copying addresses colonial issues that return to question and challenge the very notion of homeland, and "Drunk with power (Géricault in Los Andes" where the copy,  adapted to Andean latitudes, exudes a desire to restore the sacred and  auratic character of artwork as well as of the Andean imagery.Esta breve reflexión sobre la obra de Mario Conde se inicia poniendo atención en la relación particular que tiene el pintor con la técnica de la acuarela, desplegando desde esa relación una ética basada en la copia. Desde esa materialidad Conde concretiza su respuesta al momento posmoderno en que se desarrolla el arte en general, y el boliviano en particular dadas sus condiciones sociales actuales. La ética de la copia es explorada especialmente en dos de sus obras: “Ángel exterminador” donde la copia aborda temáticas coloniales que retornan para poner en cuestión y entredicho la noción de patria, y “Ebrios de poder (Géricault en Los Andes” donde la copia adaptada a latitudes andinas destila un deseo de restablecer el carácter sagrado y aurático de la obra de arte como del imaginario andino.

Conexiones revolucionarias: repercusiones de la expropiación petrolera mexicana en Bolivia, 1938

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María Cecilia Zuleta

2014-11-01

Full Text Available Este trabajo trata un tema relevante en la historiografía latinoamericana como es la expropiación petrolera mexicana durante el gobierno de Lázaro Cárdenas y aporta información original así como un enfoque innovador que desborda las historiografías estrictamente nacionales, intentando contribuir tanto a la historia de Bolivia como a la mexicana. La expropiación mexicana de 1938 alcanzó una dimensión trasnacional más allá de sus repercusiones diplomáticas: una experiencia percibida bajo muy diversos prismas en cada país latinoamericano. ¿Cómo fue vista la expropiación mexicana en los Andes bolivianos? Se argumenta que en la Paz, y en Sucre, diversos sectores de la sociedad leyeron esa expropiación tras los filtros del conflicto con la Standard Oil of Bolivia y del debate ideológico y político en torno a la recién creada YPFB, y cargaron de otro significado este episodio nacionalista al adaptarlo al contexto boliviano, dialogando simultáneamente con el sustrato previo de recepción de la revolución mexicana en la región, así como con el especial contexto político, económico y diplomático andino. Razones de orden nacional e internacional explican las reacciones ante el episodio petrolero mexicano en Bolivia, tanto como la percepción de estas por parte de la diplomacia mexicana.This article deals with a relevant subject in Latin American historiography, that being the Mexican oil expropriation during the Lázaro Cárdenas government and provides original information as well as an innovative approach that goes beyond strictly national historiographies, with the intention of contributing both to Bolivian and Mexican history. The Mexican expropriation of 1938 reached a transnational dimension beyond its diplomatic implications; an experience perceived through quite different prisms in each Latin American country. How was the Mexican expropriation viewed in the Bolivian Andes? We have argued that in La Paz and Sucre, various

Transnacionalismo andino

DEFF Research Database (Denmark)

Pærregaard, Karsten

2008-01-01

Formålet med kapitlet er at analyse den transnationale relation mellem to migrantkollektiver i USA og deres oprindelseslandsbyer i Perus højland. Analytisk koncentrerer kapitlet sig om, hvad som motiverer migranterne til at investere tid og penge i deres hjemlandsbyer, og hvordan dette engagement...

Alexela välisomanik plaanib lisaraha kaasamist. Eesti on suure raha jaoks ebahuvitav / Hannes Sarv

Index Scriptorium Estoniae

Sarv, Hannes

2011-01-01

Alexela Logisticsi omanikeringi kuuluv Puma Energy plaanib minna börsile. Puma Energy äripartneri Heiti Hääle sõnul Puma oma tegevust Eestis laiendama ei tõtta, sest siin pole kuhugi investeerida. Raivo Vare kommentaare

A new UV-curing elastomeric substrate for rapid prototyping of microfluidic devices

Science.gov (United States)

Alvankarian, Jafar; Yeop Majlis, Burhanuddin

2012-03-01

Rapid prototyping in the design cycle of new microfluidic devices is very important for shortening time-to-market. Researchers are facing the challenge to explore new and suitable substrates with simple and efficient microfabrication techniques. In this paper, we introduce and characterize a UV-curing elastomeric polyurethane methacrylate (PUMA) for rapid prototyping of microfluidic devices. The swelling and solubility of PUMA in different chemicals is determined. Time-dependent measurements of water contact angle show that the native PUMA is hydrophilic without surface treatment. The current monitoring method is used for measurement of the electroosmotic flow mobility in the microchannels made from PUMA. The optical, physical, thermal and mechanical properties of PUMA are evaluated. The UV-lithography and molding process is used for making micropillars and deep channel microfluidic structures integrated to the supporting base layer. Spin coating is characterized for producing different layer thicknesses of PUMA resin. A device is fabricated and tested for examining the strength of different bonding techniques such as conformal, corona treating and semi-curing of two PUMA layers in microfluidic application and the results show that the bonding strengths are comparable to that of PDMS. We also report fabrication and testing of a three-layer multi inlet/outlet microfluidic device including a very effective fluidic interconnect for application demonstration of PUMA as a promising new substrate. A simple micro-device is developed and employed for observing the pressure deflection of membrane made from PUMA as a very effective elastomeric valve in microfluidic devices.

LA COMUNIDAD ANDINA EN EL MARCO DE LO JURÍDICO Y POLÍTICO

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Carolina Blanco Alvarado

2013-01-01

Full Text Available El Acuerdo de Cartagena ha sido considerado como el cimiento de la “construcción inte - gracionista” de los países andinos, el cual puede seguir adelante si se adopta una visión finalmente integradora. En el presente artículo se pretende analizar el proceso andino de integración desde la faceta política y jurídica, teniendo en cuenta que la producción académica de la Comunidad Andina se ha limitado a la perspectiva económica. Los avances investigativos en dichas facetas se fundamentan, principalmente, en el análisis de la legitimidad de la Comunidad Andina de Naciones (CAN, y en la necesidad de contextualizar a los estados andinos frente a la nueva realidad mundial en aspectos que superan el ámbito económico.

Molecular detection of viral agents in free-ranging and captive neotropical felids in Brazil.

Science.gov (United States)

Furtado, Mariana M; Taniwaki, Sueli A; de Barros, Iracema N; Brandão, Paulo E; Catão-Dias, José L; Cavalcanti, Sandra; Cullen, Laury; Filoni, Claudia; Jácomo, Anah T de Almeida; Jorge, Rodrigo S P; Silva, Nairléia Dos Santos; Silveira, Leandro; Ferreira Neto, José S

2017-09-01

We describe molecular testing for felid alphaherpesvirus 1 (FHV-1), carnivore protoparvovirus 1 (CPPV-1), feline calicivirus (FCV), alphacoronavirus 1 (feline coronavirus [FCoV]), feline leukemia virus (FeLV), feline immunodeficiency virus (FIV), and canine distemper virus (CDV) in whole blood samples of 109 free-ranging and 68 captive neotropical felids from Brazil. Samples from 2 jaguars ( Panthera onca) and 1 oncilla ( Leopardus tigrinus) were positive for FHV-1; 2 jaguars, 1 puma ( Puma concolor), and 1 jaguarundi ( Herpairulus yagouaroundi) tested positive for CPPV-1; and 1 puma was positive for FIV. Based on comparison of 103 nucleotides of the UL24-UL25 gene, the FHV-1 sequences were 99-100% similar to the FHV-1 strain of domestic cats. Nucleotide sequences of CPPV-1 were closely related to sequences detected in other wild carnivores, comparing 294 nucleotides of the VP1 gene. The FIV nucleotide sequence detected in the free-ranging puma, based on comparison of 444 nucleotides of the pol gene, grouped with other lentiviruses described in pumas, and had 82.4% identity with a free-ranging puma from Yellowstone Park and 79.5% with a captive puma from Brazil. Our data document the circulation of FHV-1, CPPV-1, and FIV in neotropical felids in Brazil.

Bibliography on Cold Regions Science and Technology, Volume 53, Part 1

Science.gov (United States)

1999-12-01

Malhotra, V.M., International Conference on Devel- Yuan, R.C., Thompson, D.B., Cereal chemistry, July- Showa kichi oyobi Domu Fuji kansoku kyoteni...cryogenic system. Microflora of the deep glacier horizons of Central de Ia banda C, en los estudios del medio ambi- Antarctica. ente, sector andino y...extra- andino de la Patago- Schiek, S., Bell, G., SPIE-The International Soci- Abyzov, S.S., Mitskevich, I.N., Poglazova, M.N., nia, Argentina] Vol

Sendero Luminoso: Origins, Outlooks, and Implications.

Science.gov (United States)

1986-06-01

means. The net result was a small shortage in the regional cities of potatoes and local cereals . This was by no means catastrophic, in light of the...Indigena," in Ideologia V. Mesianica del Mundo Andino , ed. Juan M. Ossio (Lima: Grafica Morson, 1973), p. 37.- 61 with the Spanish imperial society and...Mundo Andino , ed. Juan M. Ossio (Lima: Grafica Morson, 1973), p. 118. 53Fernando Fuenzalida, "Informe Antropologico," pp. 45-47. 62 S

Indígenas andinos en Chile Colonial: Inmigración, inserción espacial, integración económica y movilidad social (Santiago, Siglos XVI-XVII

Directory of Open Access Journals (Sweden)

Valenzuela Márquez, Jaime

2010-12-01

Full Text Available Beginning with the 16th century conquering expeditions, many Andean natives who served the Spaniards arrived in Chile, where they settled in and integrated in the work and social areas of this outlying «New World»; they formed local networks and relationships, had offspring; a number of them became artisans and some drafted wills or left their mark in ecclesiastical or notarized documents that provide us with an idea of their mobility and local integration. This work offers a background and reveals the principle hubs of a process resembling a medullar structure, in order to understand how the early Chilean colonial society was made up. At the same time, it provides insights into the phenomena of movement, uprooting and settlement of the indigenous population in the southern Peruvian viceroyalty.

Desde las expediciones de conquista del siglo XVI llegaron a Chile numerosos indígenas andinos que sirvieron a los españoles, se asentaron y se integraron en los espacios laborales y sociales de este «nuevo mundo» periférico; formaron redes y parentescos locales, tuvieron descendencia, varios se transformaron en artesanos y algunos dictaron testamentos o dejaron huellas en documentos eclesiásticos y notariales que nos permiten observar su movilidad e inserción local. Este trabajo aporta antecedentes y desvela los principales ejes de un proceso que aparece como medular para entender la formación de la sociedad colonial chilena temprana y, a la vez, para dar cuenta de fenómenos de circulación, desarraigo y asentamiento de población indígena en el virreinato peruano meridional.

Poéticas andinas: Willanakuy willanakuy kasqan, Cuento es cuento

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Gonzalo Espino Relucé

2015-11-01

Full Text Available Este texto se ubica dentro de lo que se conoce como epistemologías del Sur. El enunciado básico que trabajaré será: las formas discursivas andinas están plegadas a la cosmovisión andina. La narración en los Andes está asociada a la manera como la gente concibe y vive su cotidianidad y la expresa como poética andina. La comprensión de esta supone cuatro aspectos mutuamente relacionados: (1 los relatos orales aparecen soldados a la comprensión del ser cultural andino; (2 la naturaleza distintiva del relato corresponde a la dimensión de un discurso que se justifica como ejercicio de la palabra; (3 las estrategias propias del relato andino quechua (aymara o en castellano andino enmarcan la situación del relato (un tiempo narrativo –sqa– y una manera de validar lo que se dice –s ~ –si; (4 la palabra viene acompañada de un conjunto de lenguajes que hacen posible su realización. La voz no es posible si no va acompañada del cuerpo. En nuestro artículo apelaremos a relatos que actualmente se escuchan y que provienen de la lengua quechua,  aymara y del castellano andino.

DEFORMACION CORTICAL Y PELIGRO SISMICO ASOCIADO A LA FALLA SAN RAMON EN EL FRENTE CORDILLERANO DE SANTIAGO, CHILE CENTRAL (33°S)

OpenAIRE

RAULD PLOTT, RODRIGO ANDRES; RAULD PLOTT, RODRIGO ANDRES

2011-01-01

1) El orógeno Andino es fundamentalmente bi-vergente, incluyendo un gran sistema de fallas inversas cabalgantes en el frente occidental chileno, que son sintéticas con respecto al acoplamiento tectónico causante de la orogenia Andina (subducción de la placa Nazca, oceánica, bajo la placa Sudamericana, continental); 2) El funcionamiento del Cabalgamiento Andino Occidental (West Andean Thrust, WAT), documentado por la estructura con vergencia oeste de la Cordillera Principal en Chile, tiene ...

DEVOCIONES DE INMIGRANTES: INDÍGENAS ANDINOS Y PLURIETNICIDAD URBANA EN LA CONFORMACIÓN DE COFRADÍAS COLONIALES (SANTIAGO DE CHILE, SIGLO XVII

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Jaime Valenzuela Márquez

2010-06-01

Full Text Available En los orígenes de Chile colonial nos encontramos con numerosos indígenas andinos que sirvieron a los españoles, se asentaron y se integraron en los espacios laborales y sociales de este “nuevo mundo” periférico; formaron redes y parentescos locales, tuvieron descendencia, varios se transformaron en artesanos y algunos dictaron testamentos o dejaron huellas en documentos eclesiásticos y notariales que nos permiten observar su participación en las cofradías de la capital chilena. Estas corporaciones, por su parte, si bien remiten a una finalidad eminentemente religiosa, también actúan como un canal privilegiado para la inserción y movilidad de población diversa. Bajo esta perspectiva, nuestro artículo analiza las principales cofradías en las cuales participaron estos inmigrantes, vinculando prácticas religiosas, redes sociales y espacios laborales. Las cofradías estudiadas se revelan, entonces, como instancias representativas de la diversidad de orígenes geográficos y étnicos de sus integrantes, así como de la pluralidad de referentes identitarios que circulaban e interactuaban en un escenario urbano colonial como Santiago de Chile.In the origins of colonial Chile it is possible to find numerous Andean Indians who worked for Spaniards, settled and were integrated in labor and social spaces of this peripheral “new world”. They established local nets and relationships, and had descendants. Many became craftmen and some left wills or traces on ecclesiastic and notarial documents that allow us to observe their participation in brotherhoods created in Chile’s capital. These corporations had a religious aim, but worked as privileged channels for the insertion and mobility of diverse people. Under this premise, this article analyzes the main brotherhoods in which these immigrants participated, linking religious practices with their social nets and working spaces. The brotherhoods studied reveal themselves as instances that

New World feline APOBEC3 potently controls inter-genus lentiviral transmission.

Science.gov (United States)

Konno, Yoriyuki; Nagaoka, Shumpei; Kimura, Izumi; Yamamoto, Keisuke; Kagawa, Yumiko; Kumata, Ryuichi; Aso, Hirofumi; Ueda, Mahoko Takahashi; Nakagawa, So; Kobayashi, Tomoko; Koyanagi, Yoshio; Sato, Kei

2018-04-10

The apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) gene family appears only in mammalian genomes. Some A3 proteins can be incorporated into progeny virions and inhibit lentiviral replication. In turn, the lentiviral viral infectivity factor (Vif) counteracts the A3-mediated antiviral effect by degrading A3 proteins. Recent investigations have suggested that lentiviral vif genes evolved to combat mammalian APOBEC3 proteins, and have further proposed that the Vif-A3 interaction may help determine the co-evolutionary history of cross-species lentiviral transmission in mammals. Here we address the co-evolutionary relationship between two New World felids, the puma (Puma concolor) and the bobcat (Lynx rufus), and their lentiviruses, which are designated puma lentiviruses (PLVs). We demonstrate that PLV-A Vif counteracts the antiviral action of APOBEC3Z3 (A3Z3) of both puma and bobcat, whereas PLV-B Vif counteracts only puma A3Z3. The species specificity of PLV-B Vif is irrespective of the phylogenic relationships of feline species in the genera Puma, Lynx and Acinonyx. We reveal that the amino acid at position 178 in the puma and bobcat A3Z3 is exposed on the protein surface and determines the sensitivity to PLV-B Vif-mediated degradation. Moreover, although both the puma and bobcat A3Z3 genes are polymorphic, their sensitivity/resistance to PLV Vif-mediated degradation is conserved. To the best of our knowledge, this is the first study suggesting that the host A3 protein potently controls inter-genus lentiviral transmission. Our findings provide the first evidence suggesting that the co-evolutionary arms race between lentiviruses and mammals has occurred in the New World.

Scaling for integral simulation of thermal-hydraulic phenomena in SBWR during LOCA

Energy Technology Data Exchange (ETDEWEB)

Ishii, M.; Revankar, S.T.; Dowlati, R [Purdue Univ., West Layfayette, IN (United States)] [and others

1995-09-01

A scaling study has been conducted for simulation of thermal-hydraulic phenomena in the Simplified Boiling Water Reactor (SBWR) during a loss of coolant accident. The scaling method consists of a three-level scaling approach. The integral system scaling (global scaling or top down approach) consists of two levels, the integral response function scaling which forms the first level, and the control volume and boundary flow scaling which forms the second level. The bottom up approach is carried out by local phenomena scaling which forms the third level scaling. Based on this scaling study the design of the model facility called Purdue University Multi-Dimensional Integral Test Assembly (PUMA) has been carried out. The PUMA facility has 1/4 height and 1/100 area ratio scaling, corresponding to the volume scaling of 1/400. The PUMA power scaling based on the integral scaling is 1/200. The present scaling method predicts that PUMA time scale will be one-half that of the SBWR. The system pressure for PUMA is full scale, therefore, a prototypic pressure is maintained. PUMA is designed to operate at and below 1.03 MPa (150 psi), which allows it to simulate the prototypic SBWR accident conditions below 1.03 MPa (150 psi). The facility includes models for all components of importance.

Boliivia kihutab vaesuse pärast võõrad gaasifirmad riigist välja / Arko Olesk

Index Scriptorium Estoniae

Olesk, Arko, 1981-

2006-01-01

Boliivia president Evo Morales teatas 1. mail otsusest võtta gaasitööstus riigi kontrolli alla: Boliivias gaasi tootvad välisfirmad peavad kuue kuu jooksul loovutama kontrolli tootmise üle riiklikule energiafirmale Yacimientos Petroliferos Fiscales Bolivianos. Kaart: Boliivia energiatüli

Investigating The Kinematics of Canids and Felids

Science.gov (United States)

Sur, D.

2016-12-01

For all organisms, metabolic energy is critical for survival. While moving efficiently is a necessity for large carnivores, the influence of kinematics on energy demand remains poorly understood. We measured the kinematics of dogs, wolves, and pumas to detect any differences in their respective energy expenditures. Using 22 kinematic parameters measured on 78 videos, we used one-way ANOVAs and paired T-tests to compare 5 experimental treatments among gaits in dogs (n=11 in 3 breed groups), wolves (n=2), and pumas (n=2). Across the measured parameters, we found greater kinematic similarity than expected among dog breeds and no trend in any of the 22 parameters regarding the effect of steepness on locomotion mechanics. Similarly, treadmill kinematics were nearly identical to those measured during outdoor movement. However, in 3 inches of snow, we observed significant differences (pwolf. When comparing canids (wolves and dogs) to a felid (pumas), we found that pumas and dogs are the most kinematically distinct (differing in 13 of 22 parameters, compared with 5 of 22 for wolves and pumas). Lastly, compared with wolves, walking pumas had larger head angles (p=0.0025), forelimb excursion angles (p=0.0045), and hindlimb excursion angles (p=0.0327). After comparing the energetics of pumas and dogs with their respective kinematics, we noted that less dynamic kinematics result in energy savings. Through tracking the locations and gait behavior of large carnivores, novel sensor technology can reveal how indoor kinematics applies to wild animals and improve the conservation of these species.

Recursos forestales para la vivienda

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Olga Elgueta A.

1984-06-01

Full Text Available En una visita a la Universidad del Bío-Bío, realizada por el arquitecto peruano Cristián Arbaiza, dio a conocer detalladamente cuáles fueron los propósitos que tuvo el Pacto Andino -del cual es funcionario- para ocuparse de la forestación tropical y su relación con la vivienda, aspectos considerados fundamentales en el estudio de soluciones que permitan paliar el grave déficit habitacional que afecta a los países que componen el grupo subregional andino.

Valor monetario de la leche materna en Bolivia

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Víctor M. Aguayo

2001-10-01

Full Text Available Objetivos. Estimar el volumen de leche materna consumido por los niños bolivianos de < 36 meses de edad y el valor monetario de la sustitución de dicho volumen de leche materna con sucedáneos comerciales. Métodos. Para el análisis se tuvieron en cuenta la distribución de la población infantil por grupos de edad, la prevalencia de las diferentes prácticas de lactancia materna (exclusiva o parcial en cada grupo de edad, el volumen promedio de leche materna consumido por los lactantes de un grupo de edad determinado y el costo de la producción y sustitución de la leche materna. Resultados. Los lactantes bolivianos consumen anualmente más de 161 millones de litros de leche materna, lo que representa un volumen promedio de 573 mL/día por cada lactante menor de un año. El valor monetario de la leche materna consumida por los lactantes bolivianos asciende a US$ 274 millones anuales. El costo promedio de sustituir la leche materna con sucedáneos comerciales en un lactante amamantado adecuadamente el primer año de vida asciende a US$ 407. Discusión. Para que la formulación y consolidación de políticas y programas de protección, promoción y apoyo a la lactancia materna sean una realidad, los líderes políticos de Bolivia han de tomar conciencia del enorme valor monetario de la leche materna.

Studies on Colombian cryptogams. V. Taxonomy, distribution and ecology of macrolichens of the Colombian Paramos: 1. Cladonia subgenus Cladina

NARCIS (Netherlands)

Sipman, H.J.M.; Cleef, A.M.

1979-01-01

Morphology, chemistry, distribution and ecology of 6 species of Cladonia subgenus Cladina (Lichenes) from the Colombian paramos are described: C. arcuata Ahti, C. boliviano Ahti, C. confusa Sant., C. polia Sant., C. rangiferina (L.) Wigg. var. abbayesii Ahti, and C. colombiana spec. Nov. C. bicolor

Values, animal symbolism, and human-animal relationships associated to two threatened felids in Mapuche and Chilean local narratives.

Science.gov (United States)

Herrmann, Thora M; Schüttler, Elke; Benavides, Pelayo; Gálvez, Nicolas; Söhn, Lisa; Palomo, Nadja

2013-06-13

The Chilean temperate rainforest has been subjected to dramatic fragmentation for agriculture and forestry exploitation. Carnivore species are particularly affected by fragmentation and the resulting resource use conflicts with humans. This study aimed at understanding values and human-animal relationships with negatively perceived threatened carnivores through the disclosure of local stories and Mapuche traditional folktales. Our mixed approach comprised the qualitative analysis of 112 stories on the kodkod cat (Leopardus guigna) and the puma (Puma concolor) collected by students (9-14 years) from 28 schools in the Araucania region within their family contexts, 10 qualitative in-depth interviews with indigenous Mapuche people, 35 traditional Mapuche legends, and the significance of naming found in ethnographic collections. We revealed a quasi-extinction of traditional tales in the current knowledge pool about pumas and kodkods, local anecdotes, however, were present in significant numbers. Values associated to both felids were manifold, ranging from negativistic to positive values. While pumas played an important role in people's spirituality, negative mythological connotations persisted in kodkod stories. Four prominent relationships were derived: (1) Both felids represent threats to livestock, pumas even to life, (2) both felids are symbols for upcoming negative events, (3) pumas are spiritual creatures, and (4) kodkods are threatened by humans. Recommendations are provided for stimulating new ways of perceiving unpopular and threatened carnivores among those who live in vicinity to them.

Estrategias de entrada a un oligopolio.

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Juan Benjamín Duarte Duarte

2014-12-01

Full Text Available Entre octubre de 2004 y agosto de 2005 se presentó en Colombia una guerra de precios entre las principales cementeras del país y la empresa Cementos Andino, una compañía que buscaba proteger su participación del 9% del mercado mediante estrategias de precios, su actividad de mercadeo y su posición geográfica. No es claro aún quién inició dicha situación, que finalizó con la venta de Cementos Andino. Este artículo es el resultado de una investigación realizada respecto a ese evento. Esta hace uso de la valoración con simulación de Montecarlo y de la teoría de juegos. Este trabajo permite el análisis de tres aspectos fundamentales de dicha situación: 1 las posibles causas de la venta de Cementos Andino, 2 el pensamiento estratégico en un oligopolio y 3 el papel del gobierno en estos sectores.

The Copenhagen Burnout Inventory: A new tool for the assessment of burnout

DEFF Research Database (Denmark)

Kristensen, Tage S.; Borritz, Marianne; Villadsen, Ebbe

2005-01-01

Burnout; CBI; Copenhagen Burnout Inventory; exhaustion;fatigue; human service work; psychosocial work environment; PUMA study; questionnaire validity......Burnout; CBI; Copenhagen Burnout Inventory; exhaustion;fatigue; human service work; psychosocial work environment; PUMA study; questionnaire validity...

Adidas ja Nike - nina vastu nina / Mikk Salu

Index Scriptorium Estoniae

Salu, Mikk, 1975-

2005-01-01

Spordikaupade tootja Adidas ostab Reeboki 3 miljardi euro eest. Adidase ja Reeboki ühinemisse suhtub skeptiliselt Puma, selle tegevjuht Jochen Zeitz lükkab tagasi kuuldused Nike'i ja Puma võimaliku ühinemise kohta

Prevalence of human papillomavirus infection in rural villages of the Bolivian Amazon Prevalência da infecção pelo papilomavirus humano nas aldeias rurais do Amazonas Boliviano

Directory of Open Access Journals (Sweden)

Jorge Cervantes

2003-06-01

Full Text Available Cervical cancer constitutes a major health problem in developing countries like Bolivia. The roles of certain genotypes of human papillomaviruses (HPVs in the pathogenesis of cervical cancer is well established. The prevalence of HPV infection among sexually active women varies greatly. Information regarding HPV infection in Bolivia is very much scarce, specially in regions like the Amazonian lowland. We studied 135 healthy women living in four rural localities of the Bolivian Amazon. Presence of HPV in DNA extracted from cervical swabs was analyzed using a reverse line hybridization assay. The estimated overall HPV infection prevalence among the studied rural localities was 5.9% (ranging from 0-16.6%. These values were unexpectedly low considering Bolivia has a high incidence of cervical cancer. The fact that Amazonian people seem to be less exposed to HPV, makes it likely that some other risk factors including host lifestyle behaviors and genetic background may be involved in the development of cervical cancer in this population.O câncer cervical constitui problema de saúde da maior importância nos países em desenvolvimento tais como a Bolívia. O papel de certos genótipos de papilomavirus humano (HPVs na patologia do câncer cervical está bem estabelecido. A prevalência da infecção pelo HPV nas mulheres sexualmente ativas varia amplamente. Contudo, as informações existentes acerca da infecção pelo HPV na Bolivia são muito escassas, especialmente nas zonas rurais, nomeadamente na região amazônica do país. Foram estudadas 135 mulheres saudáveis, residentes em quatro localidades do Amazonas Boliviano. Foi detectada a presença de HPV no DNA extraído de esfregaços cervicais, utilizando o método de hibridização em linha reversa. A prevalência da infecção por HVP, encontrada nas localidades rurais, foi de 5,9% (variação entre 0-16,6%. Estes valores foram inesperadamente baixos, uma vez que a Bolívia é um país com alta

Cosmovisión Aymara y su Aplicación Práctica en un Contexto Sanitario del Norte de Chile.

OpenAIRE

Valdivia, María Paz

2006-01-01

El Aymara es un pueblo andino milenario dedicado al pastoreo y a la agricultura, que tiene su origen alrededor del lago Titicaca, comprendiendo lo que en la actualidad es parte de Bolivia y Perú, norte de Chile y norte de Argentina. Todo lo relevante al orden Aymara se vincula con sus creencias que se manifiestan en ritos y ceremonias. En el mundo andino, el concepto de salud no se restringe sólo al bienestar físico y psíquico, sino que incluye el equilibrio y bienestar social y económico de...

La República peregrina: hombres de armas y letras en América Andina, 1810-1884

OpenAIRE

Thibaud, Clément

2014-01-01

Del 18 al 20 de mayo de 2005 se realizó en el Instituto de Estudios Peruanos el coloquio internacional «La República peregrina: Hombres de armas y letras en América Andina, 1810-1884». El evento, co-organizado por el Instituto Francés de Estudios Andinos y el IEP, reunió durante tres días a una veintena de historiadores especialistas en el siglo XIX, provenientes de todos los países andinos —de Chile hasta Venezuela, pasando por Argentina—, pero también de Inglaterra, Francia y Estados Unidos...

Coloquio internacional «Pensar las cárceles de América Latina»

OpenAIRE

Constant, Chloé

2014-01-01

Del 22 al 25 de abril de 2014, en las instalaciones de la Alianza Francesa de Lima, se llevó a cabo el coloquio internacional «Pensar las cárceles de América Latina» que reunió a 25 expositores, oriundos de México, El Salvador, Colombia, Venezuela, Perú, Argentina, Brasil y Francia. Organizado por Chloé Constant y Chloé Paux, el evento se realizó gracias al Servicio de Cooperación Regional para los Países Andinos de la Embajada de Francia en el Perú, al Instituto Francés de Estudios Andinos (...

El nacionalismo cosmopolita. La referencia europea en la construcción nacional de Colombia 1845-1900

Directory of Open Access Journals (Sweden)

Vera Weiler

2001-01-01

Full Text Available Frédéric Martínez, El nacionalismo cosmopolita. La referencia europea en la construcción nacional de Colombia 1845-1900. Bogotá, Banco de la Repúblicallnstituto Francés de Estudios Andinos, 2001, 580 páginas. El libro, esperado desde que su autor presentara los primeros avances de su investigación en forma de ponencias y artículos, es la traducción de una tesis doctoral sustentada en la Sorbona en 1997 y publicada en su lengua original, por el Instituto Francés de Estudios Andinos.

Evidencias fotográfica, biológica y genética de la presencia actual de jaguaroundi (Puma yagouaroundi en Michoacán, México Photographic, biological and genetic evidences of the presence of jaguaroundi (Puma yagouaroundi at the moment in Michoacán, Mexico

Directory of Open Access Journals (Sweden)

Tiberio C. Monterrubio-Rico

2012-09-01

Full Text Available El jaguaroundi, a pesar de su amplia distribución neotropical, es uno de los felinos menos estudiados del continente y se carece de estudios genéticos sobre la especie. Para el estado de Michoacán ha existido la sospecha de su presencia y no obstante que sólo se tenía un registro del año 1970, los mapas de distribución de la especie en México incluyen al estado. Combinando métodos de campo (trampas cámara, recolección de campo, transectos y genotipificación molecular, obtuvimos evidencia fotográfica, biológica y genética que confirma la presencia actual de jaguaroundi (Puma yagouaroundi en 3 regiones del estado de Michoacán, México. Se obtuvieron 11 registros fotográficos en 7 localidades con bosque tropical y 7 de estos registros, revelaron que la especie está activa principalmente por la tarde, que existen 2 fases de pelaje, predominando la fase clara y que se reproduce en el estado. Con base en las distancias e independencia entre registros de los municipios de Arteaga y Lázaro Cárdenas, se plantea la hipótesis de que la distribución continúa a lo largo de la sierra Madre del Sur y la costa del Pacífico de Michoacán, aunque se desconoce si hay conectividad hacia la depresión del Balsas. Se obtuvieron 2 secuencias de 1089 y 1096 pb del gen de citocromo b que actualmente son las más largas que se han obtenido para la especie en México y el norte del continente. Las secuencias indican que hay 2 haplotipos distintos. La presencia de la especie en 3 regiones y los 2 haplotipos permiten suponer que en Michoacán puede contar con importante diversidad genética, aunque hace falta ampliar el tamaño de muestra para confirmarlo. Las secuencias obtenidas permitirán la comparación con individuos de otras regiones del país para conocer mejor la variabilidad genética en la especie y auxiliarán en la identificación de poblaciones para conservación.The jaguaroundi is one of the least studied felids on the American

Values, animal symbolism, and human-animal relationships associated to two threatened felids in Mapuche and Chilean local narratives

Science.gov (United States)

2013-01-01

Background The Chilean temperate rainforest has been subjected to dramatic fragmentation for agriculture and forestry exploitation. Carnivore species are particularly affected by fragmentation and the resulting resource use conflicts with humans. This study aimed at understanding values and human-animal relationships with negatively perceived threatened carnivores through the disclosure of local stories and Mapuche traditional folktales. Methods Our mixed approach comprised the qualitative analysis of 112 stories on the kodkod cat (Leopardus guigna) and the puma (Puma concolor) collected by students (9-14 years) from 28 schools in the Araucania region within their family contexts, 10 qualitative in-depth interviews with indigenous Mapuche people, 35 traditional Mapuche legends, and the significance of naming found in ethnographic collections. Results We revealed a quasi-extinction of traditional tales in the current knowledge pool about pumas and kodkods, local anecdotes, however, were present in significant numbers. Values associated to both felids were manifold, ranging from negativistic to positive values. While pumas played an important role in people’s spirituality, negative mythological connotations persisted in kodkod stories. Four prominent relationships were derived: (1) Both felids represent threats to livestock, pumas even to life, (2) both felids are symbols for upcoming negative events, (3) pumas are spiritual creatures, and (4) kodkods are threatened by humans. Recommendations are provided for stimulating new ways of perceiving unpopular and threatened carnivores among those who live in vicinity to them. PMID:23764186

Primeros registros de 4 especies de felinos en el sur de Puebla, México

OpenAIRE

Farías, Verónica; Téllez, Oswaldo; Botello, Francisco; Hernández, Omar; Berruecos, Jessica; Olivares, Saúl J.; Hernández, Julio C.

2015-01-01

Se presentan los primeros registros de margay (Leopardus wiedii), gato montés (Lynx rufus), puma (Puma concolor) y jaguarundi (Puma yagouaroundi) en el sur del estado de Puebla. El trabajo de campo fue parte de una monitorización participativa que incluyó a las autoridades civiles del ejido. Se colocaron 11 estaciones de cámaras-trampa digitales que funcionaron del 18 de diciembre de 2012 al 18 de febrero de 2014. Con un esfuerzo de muestreo de 2,669 días-trampa y dentro del conjunto de regis...

Los conflictos ambientales del gas boliviano

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Gavaldá Palacín, Marc

2005-01-01

Full Text Available Los ajustes neoliberales introducidos en la legislación bolivana han facilitado la apropiación de los recursos hidrocarburíferos por parte de las transnacionales petroleras. Estas compañías invaden territorios indígenas y áreas protegidas. En su accionar generan graves conflictos ambientales con las comunidades locales. La costrucción de los gasoductos Bolivia-Brasil, Cuiabá y Gasyrg así como la oposición de la población a exportar gas a Estados Unidos nos reflejan cómo la población se organiza para resistir al expolio de las compañías petroleras. Las movilizaciones populares de ¿La Guerra del gas¿, en octubre 2003 no han terminado, porque el gas sigue en manos extranjeras.

Culture-bound syndromes in migratory contexts: the case of Bolivian immigrants.

Science.gov (United States)

Roldán-Chicano, María Teresa; Fernández-Rufete, José; Hueso-Montoro, César; García-López, María Del Mar; Rodríguez-Tello, Javier; Flores-Bienert, María Dolores

2017-07-10

to describe the culture-bound syndromes maintained by Bolivian immigrants in the new migratory context and analyze the care processes of these health problems. qualitative research with an ethnographic methodological approach. Sample: 27 Bolivian immigrants. In-depth interviews and participatory observation were the strategies used for data collection. Data were classified and categorized into logical schemes manually and using the ATLAS-ti program v.5. susto, "wayras", amartelo, pasmo de sol, pasmo de luna and pasmo de sereno are some of the folk illnesses that affect the Bolivian immigrants and that they have to treat in the new migratory context. in the new environment, the group under study preserves culture-bound syndromes that are common in their country of origin. The care strategies used for these health problems are adapted to the resources of the new context and based on interactions with the domestic environment, biomedicine and traditional medicine. It was observed the need for the health professionals to realize that the efficacy of certain therapies occurs within the scope of cultural beliefs and not in that of the scientific evidence. descrever as síndromes vinculadas à cultura mantidas pelos imigrantes bolivianos no novo contexto migratório e analisar os processos de cuidado para esses problemas de saúde. projeto de pesquisa de natureza qualitativa e com abordagem metodológica etnográfica. Amostra: 27 imigrantes bolivianos. As estratégias para a coleta de dados foram as entrevistas em profundidade e a observação participativa. Os dados foram classificados e categorizados em esquemas lógicos manualmente e por meio do programa ATLAS-ti v.5. o susto, os "wayras", o amartelo (tristeza), o pasmo de sol, o pasmo de lua e o pasmo de sereno são algumas das síndromes de caráter popular que acometem os imigrantes bolivianos, e que eles tratam no novo contexto migratório. no novo ambiente, as síndromes vinculadas à cultura, comuns em seu pa

Las sirenas de Sarhua

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Luis Millones

2011-05-01

Full Text Available El presente artículo es producto de una investigación sobre uno de los motivos más llamativos y recurrentes en las Tablas de Sarhua: la sirena.Realizamos una aproximación a este motivo, que originalmente aparece en la literatura clásica occidental, con la finalidad de explicar las razones de su presencia en el arte andino. Para tal efecto transcribimos algunos testimoniosque, desde una cosmovisión netamente andina, dan cuenta de una serie de creencias vinculadas con el ámbito musical, en el que las sirenas juegan un papel central.Palabras claves: Tablas de Sarhua, sirena, arte andino, música andina.

Canine Distemper Virus in Wild Felids of Costa Rica.

Science.gov (United States)

Avendaño, Roberto; Barrueta, Flor; Soto-Fournier, Sofía; Chavarría, Max; Monge, Otto; Gutiérrez-Espeleta, Gustavo A; Chaves, Andrea

2016-04-28

Several highly infectious diseases can be transmitted through feces and cause elevated mortality among carnivore species. One such infectious agent, canine distemper virus (CDV; Paramyxoviridae: Morbillivirus), has been reported to affect wild carnivores, among them several felid species. We screened free-ranging and captive wild carnivores in Costa Rica for CDV. Between 2006 and 2012, we collected 306 fecal samples from 70 jaguars (Panther onca), 71 ocelots ( Leopardus pardalis ), five jaguarundis (Puma yaguaroundi), 105 pumas ( Puma concolor ), five margays ( Leopardus wiedii ), 23 coyotes ( Canis latrans ), and 27 undetermined Leopardus spp. We found CDV in six individuals: one captive jaguarundi (rescued in 2009), three free-ranging ocelots (samples collected in 2012), and two free-ranging pumas (samples collected in 2007). Phylogenetic analyses were performed using sequences of the phosphoprotein (P) gene. We provide evidence of CDV in wild carnivores in Costa Rica and sequence data from a Costa Rican CDV isolate, adding to the very few sequence data available for CDV isolates from wild Central American carnivores.

Differences Between Distributed and Parallel Systems

Energy Technology Data Exchange (ETDEWEB)

Brightwell, R.; Maccabe, A.B.; Rissen, R.

1998-10-01

Distributed systems have been studied for twenty years and are now coming into wider use as fast networks and powerful workstations become more readily available. In many respects a massively parallel computer resembles a network of workstations and it is tempting to port a distributed operating system to such a machine. However, there are significant differences between these two environments and a parallel operating system is needed to get the best performance out of a massively parallel system. This report characterizes the differences between distributed systems, networks of workstations, and massively parallel systems and analyzes the impact of these differences on operating system design. In the second part of the report, we introduce Puma, an operating system specifically developed for massively parallel systems. We describe Puma portals, the basic building blocks for message passing paradigms implemented on top of Puma, and show how the differences observed in the first part of the report have influenced the design and implementation of Puma.

A INSERÇÃO DOS MOVIMENTOS INDÍGENAS NA ARENA POLÍTICA BOLIVIANA: NOVOS E VELHOS DILEMAS

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BRUNO SIQUEIRA ABE SABER MIGUEL

2008-06-01

Full Text Available ABSTRACT: Considering the Bolivian indigenous movements, the article explores the unification made by these groups between the symbolic and the instrumental universe - according to the concepts of Alain Touraine -, analyzing questions related to their historical exclusion and how this situation reflects in the Bolivian political scene, also examining the conditions that had enabled the current political emergence of the indigenous movements. Although the projection acquired by the indigenous movements, the persistence of a governmentstandard that doesn’t prioritize the constitution of public spaces to deep democracy and the presence of obstacles as the regional divisions still impose serious risks for the consolidation ofthe democracy in the country.RESUMO: Tendo como objeto os movimentos indígenas bolivianos, o trabalho explora a articulação feita por esses grupos entre o universo simbólico e o universo instrumental, conforme concepção de Alain Touraine, abordando questões relacionadas à problemáticahistórica de sua exclusão e a forma pela qual este quadro se refletiu no cenário político boliviano, analisando as condições que propiciaram a atual ascensão política dos movimentos indígenas. Como será visto, apesar de os movimentos indígenas terem adquirido certa projeção política no cenário boliviano, a persistência de um padrão de governo que não contempla e formação de espaços públicos de aprofundamento da democracia e a presença de obstáculos como as divisões regionais ainda impõem sérios riscos para a consolidação da democracia no país.

La construcción del sujeto migrante en las políticas públicas. Estudio en dos municipios del este de la provincia de Salta

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Soraya Ataide

2015-07-01

Full Text Available En Salta, como en otras provincias de nuestro país, los inmigrantes bolivianos, se han insertado fuertemente en la actividad hortícola, para consumo en fresco y con destino al mercado interno. Particularmente en algunas zonas de la provincia se reconoce su presencia en las distintas etapas de la producción. Algunos son actualmente productores (propietarios y arrendatarios y dentro de este grupo, existen quienes han logrado capitalizar la explotación, incorporando módulos o invernaderos, riego de precisión presurizado y semillas híbridas. Nos referimos a todo un paquete tecnológico que los diferencia de otro grupo de productores que producen “a campo”. A su vez, articulándose con ambos grupos de productores, encontramos trabajadores medieros y peones, también de procedencia boliviana. En este escenario, indagamos en la forma en que distintas políticas públicas de escala nacional, provincial y local, orientadas a la actividad hortícola, construyen al sujeto inmigrante, focalizando en dos municipios del este salteño. Para ello analizamos la agenda política de diferentes instituciones públicas; las acciones realizadas, pero también los textos y discursos de sus funcionarios; la representatividad de los diversos actores, en los espacios donde se modelan las políticas; y la percepción que se tiene del trabajador inmigrante. Observamos que en general se tiende a invisibilizar la heterogeneidad de roles de los sujetos de origen boliviano en la actividad. Es decir las diferencias de clase y especialmente la condición laboral precaria en que trabajan los medieros y peones bolivianos, en estos territorios productivos.

Orígenes de un desencuentro: El Partido Comunista de Chile ante el Movimiento Nacionalista Revolucionario y la dictadura de Villarroel en Bolivia (1943-1946

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Joaquín Fernández Abara

2015-06-01

Full Text Available El artículo aborda la interpretación del Partido Comunista de Chile sobre la Dictadura de Gualberto Villarroel en Bolivia y la actuación que tuvo en ella el Movimiento Nacionalista Revolucionario, entre los años 1943 y 1946. El autor sostiene que dicha interpretación estuvo marcada por el antifascismo y por una lectura de la historia boliviana teñida de tópicos liberales. Así, el nacionalismo del MNR y los militares bolivianos  fue representado como una forma de fascismo y su actuación en el concierto latinoamericano fue interpretada bajo una óptica panamericanista, considerándola como parte de un plan del Eje para dificultar la labor de los aliados en América. En esta línea, los comunistas chilenos pugnaron por que la Cancillería chilena negara el reconocimiento al gobierno boliviano y entraron en pugna con actores políticos y sindicales chilenos proclives a conceder el reconocimiento a dicho régimen.

Evolutionary and functional mitogenomics associated with the genetic restoration of the Florida panther

Science.gov (United States)

Ochoa, Alexander; Onorato, David P.; Fitak, Robert R.; Roelke-Parker, Melody; Culver, Melanie

2017-01-01

Florida panthers are endangered pumas that currently persist in reduced patches of habitat in South Florida, USA. We performed mitogenome reference-based assemblies for most parental lines of the admixed Florida panthers that resulted from the introduction of female Texas pumas into South Florida in 1995. With the addition of 2 puma mitogenomes, we characterized 174 single nucleotide polymorphisms (SNPs) across 12 individuals. We defined 5 haplotypes (Pco1–Pco5), one of which (Pco1) had a geographic origin exclusive to Costa Rica and Panama and was possibly introduced into the Everglades National Park, Florida, prior to 1995. Haplotype Pco2 was native to Florida. Haplotypes Pco3 and Pco4 were exclusive to Texas, whereas haplotype Pco5 had an undetermined geographic origin. Phylogenetic inference suggests that haplotypes Pco1–Pco4 diverged ~202000 (95% HPDI = 83000–345000) years ago and that haplotypes Pco2–Pco4 diverged ~61000 (95% HPDI = 9000–127000) years ago. These results are congruent with a south-to-north continental expansion and with a recent North American colonization by pumas. Furthermore, pumas may have migrated from Texas to Florida no earlier than ~44000 (95% HPDI = 2000–98000) years ago. Synonymous mutations presented a greater mean substitution rate than other mitochondrial functional regions: nonsynonymous mutations, tRNAs, rRNAs, and control region. Similarly, all protein-coding genes were under predominant negative selection constraints. We directly and indirectly assessed the presence of potential deleterious SNPs in the ND2 and ND5 genes in Florida panthers prior to and as a consequence of the introduction of Texas pumas. Screenings for such variants are recommended in extant Florida panthers.

Modeling connectivity to identify current and future anthropogenic barriers to movement of large carnivores: A case study in the American Southwest.

Science.gov (United States)

McClure, Meredith L; Dickson, Brett G; Nicholson, Kerry L

2017-06-01

This study sought to identify critical areas for puma ( Puma concolor ) movement across the state of Arizona in the American Southwest and to identify those most likely to be impacted by current and future human land uses, particularly expanding urban development and associated increases in traffic volume. Human populations in this region are expanding rapidly, with the potential for urban centers and busy roads to increasingly act as barriers to demographic and genetic connectivity of large-bodied, wide-ranging carnivores such as pumas, whose long-distance movements are likely to bring them into contact with human land uses and whose low tolerance both for and from humans may put them at risk unless opportunities for safe passage through or around human-modified landscapes are present. Brownian bridge movement models based on global positioning system collar data collected during bouts of active movement and linear mixed models were used to model habitat quality for puma movement; then, a wall-to-wall application of circuit theory models was used to produce a continuous statewide estimate of connectivity for puma movement and to identify pinch points, or bottlenecks, that may be most at risk of impacts from current and future traffic volume and expanding development. Rugged, shrub- and scrub-dominated regions were highlighted as those offering high quality movement habitat for pumas, and pinch points with the greatest potential impacts from expanding development and traffic, although widely distributed, were particularly prominent to the north and east of the city of Phoenix and along interstate highways in the western portion of the state. These pinch points likely constitute important conservation opportunities, where barriers to movement may cause disproportionate loss of connectivity, but also where actions such as placement of wildlife crossing structures or conservation easements could enhance connectivity and prevent detrimental impacts before they occur.

Reflexiones etnográficas sobre la «ciudadanía transnacional». Prácticas políticas de andinos en el sur de Europa

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Suárez Navaz, Liliana

2010-08-01

Full Text Available This article explores from an ethnographic perspective the political practices of migrants in a transnational public sphere, based in a study case of Andean Ecuadorians in Spain. It emphasizes the connections between the impact of immigrants settling in Madrid and their efforts to maintain a socioeconomic and political presence in their community of origin, looking at the way new practices of transnational citizenship are established in current neoliberal age. It proposes the category of transnational social fields in the bourdieuan sense to scrutinize how territory, identity and residence are redefined to build up a new cartography of inclusion and exclusion from citizenship rights and duties across national frontiers. It offers some empirical findings to illustrate the way new structures of sociocultural stratification are built both in the origin and destiny countries through these new transnational political practices. These insights are contextualized within some key theoretical debates around the new proposals of transnational citizenship.

Este trabajo explora desde una perspectiva etnográfica las prácticas políticas de migrantes en una esfera pública transnacional, en base a un estudio de caso de ecuatorianos andinos en España. Enfatiza las interconexiones que se producen entre el impacto del asentamiento de los inmigrantes en Madrid y sus esfuerzos por mantener una presencia socioeconómica y política activa en su comunidad de origen, analizando el modo en el que las nuevas prácticas de ciudadanía transnacional se configuran en la actual era neoliberal. Se propone la categoría de campo migratorio transnacional en el sentido bourdieuano para profundizar cómo el territorio, la identidad y la residencia se redefinen en una nueva cartografía de inclusión y exclusión de los derechos y deberes de ciudadanía a través de las fronteras. Se ofrecen algunos resultados empíricos que ilustran las nuevas estructuras de

Critical role of p53 upregulated modulator of apoptosis in benzyl isothiocyanate-induced apoptotic cell death.

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Marie Lue Antony

Full Text Available Benzyl isothiocyanate (BITC, a constituent of edible cruciferous vegetables, decreases viability of cancer cells by causing apoptosis but the mechanism of cell death is not fully understood. The present study was undertaken to determine the role of Bcl-2 family proteins in BITC-induced apoptosis using MDA-MB-231 (breast, MCF-7 (breast, and HCT-116 (colon human cancer cells. The B-cell lymphoma 2 interacting mediator of cell death (Bim protein was dispensable for proapoptotic response to BITC in MCF-7 and MDA-MB-231 cells as judged by RNA interference studies. Instead, the BITC-treated MCF-7 and MDA-MB-231 cells exhibited upregulation of p53 upregulated modulator of apoptosis (PUMA protein. The BITC-mediated induction of PUMA was relatively more pronounced in MCF-7 cells due to the presence of wild-type p53 compared with MDA-MB-231 with mutant p53. The BITC-induced apoptosis was partially but significantly attenuated by RNA interference of PUMA in MCF-7 cells. The PUMA knockout variant of HCT-116 cells exhibited significant resistance towards BITC-induced apoptosis compared with wild-type HCT-116 cells. Attenuation of BITC-induced apoptosis in PUMA knockout HCT-116 cells was accompanied by enhanced G2/M phase cell cycle arrest due to induction of p21 and down regulation of cyclin-dependent kinase 1 protein. The BITC treatment caused a decrease in protein levels of Bcl-xL (MCF-7 and MDA-MB-231 cells and Bcl-2 (MCF-7 cells. Ectopic expression of Bcl-xL in MCF-7 and MDA-MB-231 cells and that of Bcl-2 in MCF-7 cells conferred protection against proapoptotic response to BITC. Interestingly, the BITC-treated MDA-MB-231 cells exhibited induction of Bcl-2 protein expression, and RNA interference of Bcl-2 in this cell line resulted in augmentation of BITC-induced apoptosis. The BITC-mediated inhibition of MDA-MB-231 xenograft growth in vivo was associated with the induction of PUMA protein in the tumor. In conclusion, the results of the present study

Investment opportunities with YPFB capitalization

International Nuclear Information System (INIS)

Escobar, F.

1996-01-01

Investment opportunities with Yacimientos Petroliferos Fiscales Bolivianos (LPFB) in La Paz, Bolivia, were discussed, especially as they may be affected by the new Hydrocarbon Law No. 1689, whose main objective is to encourage investments in Bolivia and to increase production capacity through investors' incorporation. Some of the areas of potential importance examined included reserve development, transportation, upstream consulting, and hydrocarbon development

Lenguaje y cognición en la cosmovisión andina

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Félix Quesada Castillo

2011-05-01

Full Text Available Se analiza la categoría de número en el sistema de persona en las lenguas quechua y aimara. El análisis se sustenta en consideraciones tanto diacrónicas como sincrónicas y el autor evalúa las propuestas inscritas en la lingüística andina. Sobre la base de este análisis, se establece la posiblecorrelación del sistema morfológico con la cosmovisión del hombre andino.Al respecto, el autor incide en las sustantivas diferencias de la cognición andina con respecto a la estructura morfológica de una lengua occidental como la castellana. Palabras claves: Quechua, aimara, cognición, sistema de persona, cosmovisión andina.

Ocelot Population Status in Protected Brazilian Atlantic Forest.

Science.gov (United States)

Massara, Rodrigo Lima; Paschoal, Ana Maria de Oliveira; Doherty, Paul Francis; Hirsch, André; Chiarello, Adriano Garcia

2015-01-01

Forest fragmentation and habitat loss are detrimental to top carnivores, such as jaguars (Panthera onca) and pumas (Puma concolor), but effects on mesocarnivores, such as ocelots (Leopardus pardalis), are less clear. Ocelots need native forests, but also might benefit from the local extirpation of larger cats such as pumas and jaguars through mesopredator release. We used a standardized camera trap protocol to assess ocelot populations in six protected areas of the Atlantic forest in southeastern Brazil where over 80% of forest remnants are forest cover, number of free-ranging domestic dogs and presence of top predators. Ocelot abundance was positively correlated with reserve size and the presence of top predators (jaguar and pumas) and negatively correlated with the number of dogs. We also found higher detection probabilities in less forested areas as compared to larger, intact forests. We suspect that smaller home ranges and higher movement rates in smaller, more degraded areas increased detection. Our data do not support the hypothesis of mesopredator release. Rather, our findings indicate that ocelots respond negatively to habitat loss, and thrive in large protected areas inhabited by top predators.

Social interactions in a solitary carnivore

Institute of Scientific and Technical Information of China (English)

L.Mark ELBROCH; Howard QUIGLEY

2017-01-01

In total,177 of 245 terrestrial carnivores are described as solitary,and much of carnivore ecology is built on the assumptions that interactions between adult solitary carnivores are rare.We employed Global Positioning System (GPS) technology and motion-triggered cameras to test predictions of land-tenure territoriality and the resource dispersion hypothesis in a territorial carnivore,the puma Puma concolor.We documented 89 independent GPS interactions,60％ of which occurred at puma kills (n=53),59 camera interactions,11 (17％) of which captured courtship behaviors,and 5 other interactions (1 F-F,3 M-F,and 1 M-M).Mean minimum weekly contact rates were 5.5 times higher in winter,the season when elk Cervus elaphus were aggregated at lower elevations and during which puma courtship primarily occurred.In winter,contacts rates were 0.6± 0.3 (standard deviation (SD)) interactions/week vs.0.1 ± 0.1 (SD) interactions/week during summer.The preponderance of interactions at food sources supported the resource dispersion hypothesis,which predicts that resource fluxes can explain temporary social behaviors that do not result in any apparent benefits for the individuals involved.Conspecific tolerance is logical when a prey is so large that the predator that killed it cannot consume it entirely,and thus,the costs of tolerating a conspecific sharing the kill are less than the potential costs associated with defending it and being injured.Puma aggregations at kills numbered as high as 9,emphasizing the need for future research on what explains tolerance among solitary carnivores.

NF-kappaB and p53 are the dominant apoptosis-inducing transcription factors elicited by the HIV-1 envelope.

Science.gov (United States)

Perfettini, Jean-Luc; Roumier, Thomas; Castedo, Maria; Larochette, Nathanael; Boya, Patricia; Raynal, Brigitte; Lazar, Vladimir; Ciccosanti, Fabiola; Nardacci, Roberta; Penninger, Josef; Piacentini, Mauro; Kroemer, Guido

2004-03-01

The coculture of cells expressing the HIV-1 envelope glycoprotein complex (Env) with cells expressing CD4 results into cell fusion, deregulated mitosis, and subsequent cell death. Here, we show that NF-kappaB, p53, and AP1 are activated in Env-elicited apoptosis. The nuclear factor kappaB (NF-kappaB) super repressor had an antimitotic and antiapoptotic effect and prevented the Env-elicited phosphorylation of p53 on serine 15 and 46, as well as the activation of AP1. Transfection with dominant-negative p53 abolished apoptosis and AP1 activation. Signs of NF-kappaB and p53 activation were also detected in lymph node biopsies from HIV-1-infected individuals. Microarrays revealed that most (85%) of the transcriptional effects of HIV-1 Env were blocked by the p53 inhibitor pifithrin-alpha. Macroarrays led to the identification of several Env-elicited, p53-dependent proapoptotic transcripts, in particular Puma, a proapoptotic "BH3-only" protein from the Bcl-2 family known to activate Bax/Bak. Down modulation of Puma by antisense oligonucleotides, as well as RNA interference of Bax and Bak, prevented Env-induced apoptosis. HIV-1-infected primary lymphoblasts up-regulated Puma in vitro. Moreover, circulating CD4+ lymphocytes from untreated, HIV-1-infected donors contained enhanced amounts of Puma protein, and these elevated Puma levels dropped upon antiretroviral therapy. Altogether, these data indicate that NF-kappaB and p53 cooperate as the dominant proapoptotic transcription factors participating in HIV-1 infection.

Aportes amazonicos al formativo andino*

OpenAIRE

Morales Chocano, Daniel

2014-01-01

RESUMEN La tesis de J.C Tello sobre los orígenes amazónicos de la cultura Chavín ha tenido en la iconografía amazónica presente en Chavin sus argumentos mas fuertes, sin embargo, falta mucho por investigar el aspecto ideológico que representan esos iconos como el jaguar, las cabezas trofeo y el uso de alucinógenos, los cuales indudablemente se vinculan al chamanismo amazónico.

Estructura comunitaria de diatomeas presentes en los sedimentos superficiales de ocho lagos andinos de Chile central Diatoms community structure in superficial sediments of eight Andean lakes of central Chile

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INGRID E ALVIAL

2008-03-01

Full Text Available En este trabajo se analizó la estructura comunitaria de diatomeas depositadas en los sedimentos superficiales de ocho lagos andinos chilenos ubicados entre los 32°49' y 38°48' S. Se encontró un total de 99 taxa de diatomeas, distribuidos en 48 géneros. Del total de taxa, 74 fueron identificados a nivel de especie siendo todos ellos cosmopolitas a excepción de Eunotia andinofrequens, Gomphonema punae, Pinnularia araucanensis y Pinnularia acidicola, entre otras, que están descritos solo para el Hemisferio Sur. Por otro lado, las muestras analizadas presentaron distinta composición florística de diatomeas. De esta manera, en los ensambles diatomológicos depositados en los sedimentos de las lagunas de altura Ocho, Huifa, Ensueño y Negra ubicadas sobre los 2.860 m del nivel del mar, abundaron especies bentónicas, típicas de aguas oligotróficas y acidas como Achnanthidium exiguum, Achnanthidium minutissimum, Encyonema minutum, Pinnularia acidicola y Planothidium lanceolatum. En los ensambles diatomológicos de los lagos Galletué, Icalma y Laja, ubicados bajo los 1.360 m del nivel del mar, abundaron diatomeas planctónicas, características de aguas alcalinas y mesotróficas como Asterionella formosa, Aulacoseira distans, Aulacoseira granulata, Cyclotella stelligera y Rhopalodia gibbaIn this research the taxonomic structure of diatoms in sediments of high mountain lakes was studied. These lakes are located in Chile between 32°49' and 38°48' S in the Andean Cordillera. A total of 99 diatom taxa distributed in 48 genera were identified and all this taxa are cosmopolitan excepting a Eunotia andinofrequens, Gomphonema punae, Pinnularia araucanensis and Pinnularia acidicola, which are know only for the Southern Hemisphere. The assemblages of diatoms were different in the studied lakes. So the high mountain lakes Ocho, Huifa, Ensueño and Negra, dominated benthic diatoms which are typical of oligotrophic and acid waters as Achnanthidium

EWS Knockdown and Taxifolin Treatment Induced Differentiation and Removed DNA Methylation from p53 Promoter to Promote Expression of Puma and Noxa for Apoptosis in Ewing's Sarcoma.

Science.gov (United States)

Hossain, Mohammad Motarab; Ray, Swapan Kumar

2014-10-01

Ewing's sarcoma is a pediatric tumor that mainly occurs in soft tissues and bones. Malignant characteristics of Ewing's sarcoma are correlated with expression of EWS oncogene. We achieved knockdown of EWS expression using a plasmid vector encoding EWS short hairpin RNA (shRNA) to increase anti-tumor mechanisms of taxifolin (TFL), a new flavonoid, in human Ewing's sarcoma cells in culture and animal models. Immunofluorescence microscopy and flow cytometric analysis showed high expression of EWS in human Ewing's sarcoma SK-N-MC and RD-ES cell lines. EWS shRNA plus TFL inhibited 80% cell viability and caused the highest decreases in EWS expression at mRNA and protein levels in both cell lines. Knockdown of EWS expression induced morphological features of differentiation. EWS shRNA plus TFL caused more alterations in molecular markers of differentiation than either agent alone. EWS shRNA plus TFL caused the highest decreases in cell migration with inhibition of survival, angiogenic and invasive factors. Knockdown of EWS expression was associated with removal of DNA methylation from p53 promoter, promoting expression of p53, Puma, and Noxa. EWS shRNA plus TFL induced the highest amounts of apoptosis with activation of extrinsic and intrinsic pathways in both cell lines in culture. EWS shRNA plus TFL also inhibited growth of Ewing's sarcoma tumors in animal models due to inhibition of differentiation inhibitors and angiogenic and invasive factors and also induction of activation of caspase-3 for apoptosis. Collectively, knockdown of EWS expression increased various anti-tumor mechanisms of TFL in human Ewing's sarcoma in cell culture and animal models.

Concursos

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Boletín Cultural y Bibliográfico Banco de la República

1995-09-01

Full Text Available Se presenta la información y las bases para los siguientes concursos; Concurso Enka de literatura infantil Premio Andino; Becas para Jóvenes Talentos en Música y Artes Plásticas.

Société civile et pouvoirs publics : Partenaires pour une économie ...

International Development Research Centre (IDRC) Digital Library (Canada)

Studies. Estudio de casos brasileños : la dinámica de relaciones entre los foros de economía solidaria y las políticas públicas para la economía solidaria en Brasil. Download PDF. Studies. Estudio de casos bolivianos : las políticas públicas de economía social y el diálogo entre los poderes públicos y la sociedad civil.

Société civile et pouvoirs publics : Partenaires pour une économie ...

International Development Research Centre (IDRC) Digital Library (Canada)

Canada case study : co-construction of public policy for the social economy. Études. Estudio de casos brasileños : la dinámica de relaciones entre los foros de economía solidaria y las políticas públicas para la economía solidaria en Brasil. Études. Estudio de casos bolivianos : las políticas públicas de economía social y el ...

Analisis de la microbiota en suelos cultivados del Altiplano central

OpenAIRE

Sivila, R.; Hervé, Dominique

2001-01-01

Se estudio la poblacion microbina en una rotacion de cultivos con descanso, comun en el Altiplano Central boliviano. Se determino la presencia y densidad de cuatro grupos taxonomicos de microorganismos: bacterias; hongos, actinomicetos y esporas de las micorrizas arbusculares en el suelo rizosferico de cuatro cultivos de la rotacion (papa, quinua, cebada y avena); en las principales especies silvestres perennes (#Stipa ichu, Festuca dolichophylla, Baccharis incarum$) que colonizan las parcela...

Princeton University Materials Academy for underrepresented students

Science.gov (United States)

Steinberg, Daniel; Rodriguez Martinez, Sara; Cody, Linda

Summer 2016 gave underrepresented high school students from Trenton New Jersey the opportunity to learn materials science, sustainability and the physics and chemistry of energy storage from Princeton University professors. New efforts to place this curriculum online so that teachers across the United States can teach materials science as a tool to teach ``real'' interdisciplinary science and meet the new Next Generation Science Standards (NGSS). The Princeton University Materials Academy (PUMA) is an education outreach program for underrepresented high school students. It is part of the Princeton Center for Complex Materials (PCCM), a National Science Foundation (NSF) funded Materials Research Engineering and Science Center (MRSEC). PUMA has been serving the community of Trenton New Jersey which is only eight miles from the Princeton University campus. We reached over 250 students from 2003-2016 with many students repeating for multiple years. 100% of our PUMA students have graduated high school and 98% have gone on for college. This is compared with overall Trenton district graduation rate of 48% and a free and reduced lunch of 83%. We discuss initiatives to share the curriculum online to enhance the reach of PCCM' PUMA and to help teachers use materials science to meet NGSS and give their students opportunities to learn interdisciplinary science. MRSEC, NSF (DMR-1420541).

Ocelot Population Status in Protected Brazilian Atlantic Forest.

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Rodrigo Lima Massara

Full Text Available Forest fragmentation and habitat loss are detrimental to top carnivores, such as jaguars (Panthera onca and pumas (Puma concolor, but effects on mesocarnivores, such as ocelots (Leopardus pardalis, are less clear. Ocelots need native forests, but also might benefit from the local extirpation of larger cats such as pumas and jaguars through mesopredator release. We used a standardized camera trap protocol to assess ocelot populations in six protected areas of the Atlantic forest in southeastern Brazil where over 80% of forest remnants are < 50 ha. We tested whether variation in ocelot abundance could be explained by reserve size, forest cover, number of free-ranging domestic dogs and presence of top predators. Ocelot abundance was positively correlated with reserve size and the presence of top predators (jaguar and pumas and negatively correlated with the number of dogs. We also found higher detection probabilities in less forested areas as compared to larger, intact forests. We suspect that smaller home ranges and higher movement rates in smaller, more degraded areas increased detection. Our data do not support the hypothesis of mesopredator release. Rather, our findings indicate that ocelots respond negatively to habitat loss, and thrive in large protected areas inhabited by top predators.

Development of a facility using robotics for testing automation of inertial instruments

Science.gov (United States)

Greig, Joy Y.; Lamont, Gary B.; Biezad, Daniel J.; Lewantowicz, Zdsislaw H.; Greig, Joy Y.

1987-01-01

The Integrated Robotics System Simulation (ROBSIM) was used to evaluate the performance of the PUMA 560 arm as applied to testing of inertial sensors. Results of this effort were used in the design and development of a feasibility test environment using a PUMA 560 arm. The implemented facility demonstrated the ability to perform conventional static inertial instrument tests (rotation and tumble). The facility included an efficient data acquisitions capability along with a precision test servomechanism function resulting in various data presentations which are included in the paper. Analysis of inertial instrument testing accuracy, repeatability and noise characteristics are provided for the PUMA 560 as well as for other possible commercial arm configurations. Another integral aspect of the effort was an in-depth economic analysis and comparison of robot arm testing versus use of contemporary precision test equipment.

ENTRE LO INDIO, LO NEGRO Y LO INCAICO: LA JERARQUÍA ESPACIAL DE LA DIFERENCIA EN EL PERÚ MULTICULTURAL

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Shane Greene

2010-01-01

Full Text Available Este artículo examina los problemas encontrados por un programa estatal sobre multiculturalismo afro-indígena en Perú dentro del marco de la historia intelectual de la nación, sus regiones, y las ideologías que las gobiernan. En vez de presentar un recuento comparativo sobre las políticas aplicadas a afro-descendientes e indígenas a nivel regional Latinoamericano enfatizando «raza» versus «cultura» arguyo que se debe prestar más atención a las formas en las que el multiculturalismo afro-indígena se «peruaniza» en el proceso de la expansión global/regional. El caso peruano es particularmente interesante por la forma en la que el Estado separa sus sujetos multiculturales por región (reconociendo los andinos, amazónicos, y afroperuanos que son implícitamente de la costa. También analizo cómo la larga fascinación de la nación con la figura del inca permite que los andinos tengan un estatus de elite indígena dentro de la imaginación multicultural. La influencia histórica de lo que llamo el «apartado inca» sugiere posibilidades para poder comparar todos aquellos sujetos definidos como no andinos / no incas, y particularmente para los afroperuanos e indígenas amazónicos en este contexto.

Arquitectura y vivienda campesina en tres pueblos andinos: Yanque, Lari y Coporaque en el valle del río Colca, Arequipa

Directory of Open Access Journals (Sweden)

1994-01-01

hasta el presente. Este trabajo aporta un testimonio histórico y antropológico que podría ser un modelo valioso para realizar un análisis comparativo con los pueblos en otros valles andinos. ARCHITECTURE AND PEASANT HOMES IN THREE ANDEAN VILLAGES: YANQUE, LARI AND COPORAQUE IN THE COLCA VALLEY, PERU. This essay discusses the civil architecture in Yanque, Lari and Coporaque, three of the 16 'Indians villages' founded in the Colca Valley of southern Peru in the 1570s, during the rule of Viceroy Francisco de Toledo. The first part of the article describes the general layout of the villages and their architectural characteristics. The second part enters more fully into the technology and use of villagers' homes and compares traditional 'modern' styles and building materials. Contemporary historical and anthropological literature offers little information on the subject of peasant housing in peruvian mountain villages. Hopefully, this essay will be of value for comparative research in other Andean villages.

DE CHARANGO A CHILLADOR. CONFLUENCIAS MUSICALES EN LA ESTUDIANTINA ALTIPLANICA.

OpenAIRE

PONCE VALDIVIA, OMAR PERCY; PONCE VALDIVIA, OMAR PERCY

2008-01-01

En el presente trabajo enfocaremos un proceso musical que ha estado distante de las construcciones discursivas acerca del instrumento andino denominado charango, tanto desde las referencias escritas, como desde las asunciones ideológicas de lo nacional y 179p.

Pathogen exposure varies widely among sympatric populations of wild and domestic felids across the United States.

Science.gov (United States)

Carver, Scott; Bevins, Sarah N; Lappin, Michael R; Boydston, Erin E; Lyren, Lisa M; Alldredge, Mathew; Logan, Kenneth A; Sweanor, Linda L; Riley, Seth P D; Serieys, Laurel E K; Fisher, Robert N; Vickers, T Winston; Boyce, Walter; Mcbride, Roy; Cunningham, Mark C; Jennings, Megan; Lewis, Jesse; Lunn, Tamika; Crooks, Kevin R; Vandewoude, Sue

2016-03-01

Understanding how landscape, host, and pathogen traits contribute to disease exposure requires systematic evaluations of pathogens within and among host species and geographic regions. The relative importance of these attributes is critical for management of wildlife and mitigating domestic animal and human disease, particularly given rapid ecological changes, such as urbanization. We screened > 1000 samples from sympatric populations of puma (Puma concolor), bobcat (Lynx rufus), and domestic cat (Felis catus) across urban gradients in six sites, representing three regions, in North America for exposure to a representative suite of bacterial, protozoal, and viral pathogens (Bartonella sp., Toxoplasma gondii, feline herpesvirus-1, feline panleukopenea virus, feline calicivirus, and feline immunodeficiency virus). We evaluated prevalence within each species, and examined host trait and land cover determinants of exposure; providing an unprecedented analysis of factors relating to potential for infections in domesticated and wild felids. Prevalence differed among host species (highest for puma and lowest for domestic cat) and was greater for indirectly transmitted pathogens. Sex was inconsistently predictive of exposure to directly transmitted pathogens only, and age infrequently predictive of both direct and indirectly transmitted pathogens. Determinants of pathogen exposure were widely divergent between the wild felid species. For puma, suburban land use predicted increased exposure to Bartonella sp. in southern California, and FHV-1 exposure increased near urban edges in Florida. This may suggest interspecific transmission with domestic cats via flea vectors (California) and direct contact (Florida) around urban boundaries. Bobcats captured near urban areas had increased exposure to T. gondii in Florida, suggesting an urban source of prey Bobcats captured near urban areas in Colorado and Florida had higher FIV exposure, possibly suggesting increased intraspecific

Experimental investigation of void distribution in Suppression Pool during the initial blowdown period of a Loss of Coolant Accident using air–water two-phase mixture

International Nuclear Information System (INIS)

Rassame, Somboon; Griffiths, Matthew; Yang, Jun; Lee, Doo Yong; Ju, Peng; Choi, Sung Won; Hibiki, Takashi; Ishii, Mamoru

2014-01-01

Highlights: • Basic understanding of the venting phenomena in the SP during a LOCA was obtained. • A series of experiment is carried out using the PUMA-E test facility. • Two phases of experiments, namely, an initial and a quasi-steady phase were observed. • The maximum void penetration depth was experienced during the initial phase. - Abstract: During the initial blowdown period of a Loss of Coolant Accident (LOCA), the non-condensable gas initially contained in the BWR containment is discharged to the pressure suppression chamber through the blowdown pipes. The performance of Emergency Core Cooling System (ECCS) can be degraded due to the released gas ingestion into the suction intakes of the ECCS pumps. The understanding of the relevant phenomena in the pressure suppression chamber is important in analyzing potential gas intrusion into the suction intakes of ECCS pumps. To obtain the basic understanding of the relevant phenomena and the generic data of void distribution in the pressure suppression chamber during the initial blowdown period of a LOCA, tests with various blowdown conditions were conducted using the existing Suppression Pool (SP) tank of the integral test facility, called Purdue University Multi-Dimensional Integral Test Assembly for ESBWR applications (PUMA-E) facility, a scaled downcomer pipe installed in the PUMA-E SP, and air discharge pipe system. Two different diameter sizes of air injection pipe (0.076 and 0.102 m), a range of air volumetric flux (7.9–24.7 m/s), initial void conditions in an air injection pipe (fully void, partially void, and fully filled with water) and different air velocity ramp rates (1.0, 1.5, and 2.0 s) are used to investigate the impact of the blowdown conditions to the void distribution in the SP. Two distinct phases of experiments, namely, an initial and a quasi-steady phase were observed. The maximum void penetration depth was experienced during the initial phase. The quasi-steady phase provided less void

Civil Society and Public Powers : Partners for Social Economy and ...

International Development Research Centre (IDRC) Digital Library (Canada)

Études. Estudio de casos brasileños : la dinámica de relaciones entre los foros de economía solidaria y las políticas públicas para la economía solidaria en Brasil. Téléchargez le PDF. Études. Estudio de casos bolivianos : las políticas públicas de economía social y el diálogo entre los poderes públicos y la sociedad civil.

Characterization of regionally associated feline immunodeficiency virus (FIV) in bobcats (Lynx rufus).

Science.gov (United States)

Lagana, Danielle M; Lee, Justin S; Lewis, Jesse S; Bevins, Sarah N; Carver, Scott; Sweanor, Linda L; McBride, Roy; McBride, Caleb; Crooks, Kevin R; VandeWoude, Sue

2013-07-01

Feline immunodeficiency virus (FIV) classically infects felid species with highly divergent species-specific FIVs. However, recent studies have detected an FIV strain infecting both bobcats (Lynx rufus) and pumas (Puma concolor) in California and Florida. To further investigate this observation, we evaluated FIV from bobcats in Florida (n=25) and Colorado (n=80) between 2008 and 2011. Partial viral sequences from five Florida bobcats cluster with previously published sequences from Florida panthers. We did not detect FIV in Colorado bobcats.

Glass fiber sensors for detecting special nuclear materials at portal and monitor stations

International Nuclear Information System (INIS)

Hull, C.D.; Seymour, R.; Crawford, T.; Bliss, M.; Craig, R.A.

2001-01-01

Nuclear Safeguards and Security Systems LLC (NucSafe) participated in the Illicit Trafficking Radiation Assessment Program (ITRAP) recently conducted by the Austrian Research Center, Seibersdorf (ARCS) for IAEA, INTERPOL, and the World Customs Organization (IAEA, in press). This presentation reviews ITRAP test results of NucSafe instrumentation. NucSafe produces stationary, mobile, and hand-held systems that use neutron and gamma ray sensors to detect Special Nuclear Materials (SNM). Neutron sensors are comprised of scintillating glass fibers (trade name 'PUMA' for Pu Materials Analysis), which provide several advantages over 3 He and 10 BF 3 tubes. PUMA 6 Li glass fiber sensors offer greater neutron sensitivity and dynamic counting range with significantly less microphonic susceptibility than tubes, while eliminating transport and operational hazards. PUMA sensors also cost less per active area than gas tubes, which is important since rapid neutron detection at passenger, freight, and vehicle portals require large sensor areas to provide the required sensitivity

Suberoyl bis-hydroxamic acid induces p53-dependent apoptosis of MCF-7 breast cancer cells

Institute of Scientific and Technical Information of China (English)

Zhi-gang ZHUANG; Fei FEI; Ying CHEN; Wei JIN

2008-01-01

Aim: To study the effects of suberoyl bis-hydroxamic acid (SBHA), an inhibitor of histone deacetylases, on the apoptosis of MCF-7 breast cancer cells. Meth-ods: Apoptosis in MCF-7 cells induced by SBHA was demonstrated by flow cytometric analysis, morphological observation, and DNA ladder. Mitochondrial membrane potential (△ψm) was measured using the fluorescent probe JC-1. The expressions of p53, p21, Bax, and PUMA were determined using RT-PCR or Western blotting analysis after the MCF-7 cells were treated with SBHA or p53 siRNA. Results: SBHA induced apoptosis in MCF-7 cells. The expressions of p53, p21, Bax, and PUMA were induced, and △ψm collapsed after treatment with SBHA. p53 siRNA abrogated the SBHA-induced apoptosis and the expressions of p53, p21, Bax, and PUMA. Conclusion: The activation of the p53 pathway is involved in SBHA-induced apoptosis in MCF-7 cells.

La indiferencia ante los derechos humanos y la educación moderno en un régimen populista. La ideología de la descolonización Bolivia

OpenAIRE

H. C. F., Mansilla

2013-01-01

La ideología de la descolonización es sostenida por el gobierno boliviano como parte de plan- teamientos de origen indianista e indigenista. El argumento de la descolonización sostiene que la sociedad indígena precolonial fue igualitaria y solidaria. Por otra parte, ha desarrollado una visión negativa de la modernidad. Un aspecto principal de la sociedad boliviana ha sido la tra- dición autoritaria que es ignorada por indianistas e indigenistas.

El espejo europeo

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Jorge Orlando Melo

2001-01-01

Full Text Available El nacionalismo cosmopolita. La referencia europea en la construcción nacional en Colombia, 1845-1900. Frédéric Martínez. Banco de la República, Instituto Francés de Estudios Andinos, Bogotá, 2001, 580 págs.

Liberales, protestantes y masones, modernidad y tolerancia religiosa. Perú, siglo XIX. [Reseña

OpenAIRE

Cuesta-Alonso, M.R. (Marcelino R.)

1999-01-01

Reseña de: Fernando ARMAS ASÍN, Liberales, protestantes y masones, modernidad y tolerancia religiosa. Perú, siglo XIX, Centro de Estudios Regionales Andinos «Bartolomé de las Casas» - Pontificia Universidad Católica del Perú, Cusco (Perú) 1998, 298 pp.

Decreased expression of MUC1 induces apoptosis and inhibits migration in pancreatic cancer PANC-1 cells via regulation of Slug pathway.

Science.gov (United States)

Zhao, Ping; Meng, Meng; Xu, Bin; Dong, Aiping; Ni, Guangzhen; Lu, Lianfang

2017-12-06

MUC1, a membrane tethered mucin glycoprotein, is overexpressed in > 60% of human pancreatic cancers (PCs), and is associated with poor prognosis and enhanced metastasis. Here, we report the effect of silencing MUC1 expression on the growth, migration and invasive ability of pancreatic cancer cells, and explored its mechanisms. We observed that siRNA mediated suppression of the MUC1 expression significantly reduced invasive and migrative capability and induced apoptosis of the pancreatic cancer PANC-1 cells. We found that Slug was inhibited in the MUC1 siRNA transfected PANC-1 cells (MUC1 siRNA/PANC-1 cells). Expression of PUMA and E-cadherin was increased in the MUC1 siRNA/PANC-1 cells. PANC-1 cells overexpressing full long Slug gene (when transfected with Slug cDNA plasmid) significantly inhibited PUMA and E-cadherin expression in the MUC1 siRNA/PANC-1 cells. Silencing PUMA expression inhibited apoptosis in the MUC1 siRNA transfected PANC-1 cells (MUC1 siRNA/PANC-1 cells). Silencing E-cadherin expression restored the invasion and migration ability in the MUC1 siRNA/PANC-1 cells. We therefore concluded that silencing MUC1 expression inhibited migration and invasion, and induced apoptosis of PANC-1 cells via downregulation of Slug and upregulation of Slug dependent PUMA and E-cadherin expression. MUC1 could serve as a potential therapeutic target in pancreatic cancer.

Seroprevalence and genomic divergence of circulating strains of feline immunodeficiency virus among Felidae and Hyaenidae species.

Science.gov (United States)

Troyer, Jennifer L; Pecon-Slattery, Jill; Roelke, Melody E; Johnson, Warren; VandeWoude, Sue; Vazquez-Salat, Nuria; Brown, Meredith; Frank, Laurence; Woodroffe, Rosie; Winterbach, Christiaan; Winterbach, Hanlie; Hemson, Graham; Bush, Mitch; Alexander, Kathleen A; Revilla, Eloy; O'Brien, Stephen J

2005-07-01

Feline immunodeficiency virus (FIV) infects numerous wild and domestic feline species and is closely related to human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV). Species-specific strains of FIV have been described for domestic cat (Felis catus), puma (Puma concolor), lion (Panthera leo), leopard (Panthera pardus), and Pallas' cat (Otocolobus manul). Here, we employ a three-antigen Western blot screening (domestic cat, puma, and lion FIV antigens) and PCR analysis to survey worldwide prevalence, distribution, and genomic differentiation of FIV based on 3,055 specimens from 35 Felidae and 3 Hyaenidae species. Although FIV infects a wide variety of host species, it is confirmed to be endemic in free-ranging populations of nine Felidae and one Hyaenidae species. These include the large African carnivores (lion, leopard, cheetah, and spotted hyena), where FIV is widely distributed in multiple populations; most of the South American felids (puma, jaguar, ocelot, margay, Geoffroy's cat, and tigrina), which maintain a lower FIV-positive level throughout their range; and two Asian species, the Pallas' cat, which has a species-specific strain of FIV, and the leopard cat, which has a domestic cat FIV strain in one population. Phylogenetic analysis of FIV proviral sequence demonstrates that most species for which FIV is endemic harbor monophyletic, genetically distinct species-specific FIV strains, suggesting that FIV transfer between cat species has occurred in the past but is quite infrequent today.

Seroprevalence and Genomic Divergence of Circulating Strains of Feline Immunodeficiency Virus among Felidae and Hyaenidae Species†

Science.gov (United States)

Troyer, Jennifer L.; Pecon-Slattery, Jill; Roelke, Melody E.; Johnson, Warren; VandeWoude, Sue; Vazquez-Salat, Nuria; Brown, Meredith; Frank, Laurence; Woodroffe, Rosie; Winterbach, Christiaan; Winterbach, Hanlie; Hemson, Graham; Bush, Mitch; Alexander, Kathleen A.; Revilla, Eloy; O'Brien, Stephen J.

2005-01-01

Feline immunodeficiency virus (FIV) infects numerous wild and domestic feline species and is closely related to human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV). Species-specific strains of FIV have been described for domestic cat (Felis catus), puma (Puma concolor), lion (Panthera leo), leopard (Panthera pardus), and Pallas' cat (Otocolobus manul). Here, we employ a three-antigen Western blot screening (domestic cat, puma, and lion FIV antigens) and PCR analysis to survey worldwide prevalence, distribution, and genomic differentiation of FIV based on 3,055 specimens from 35 Felidae and 3 Hyaenidae species. Although FIV infects a wide variety of host species, it is confirmed to be endemic in free-ranging populations of nine Felidae and one Hyaenidae species. These include the large African carnivores (lion, leopard, cheetah, and spotted hyena), where FIV is widely distributed in multiple populations; most of the South American felids (puma, jaguar, ocelot, margay, Geoffroy's cat, and tigrina), which maintain a lower FIV-positive level throughout their range; and two Asian species, the Pallas' cat, which has a species-specific strain of FIV, and the leopard cat, which has a domestic cat FIV strain in one population. Phylogenetic analysis of FIV proviral sequence demonstrates that most species for which FIV is endemic harbor monophyletic, genetically distinct species-specific FIV strains, suggesting that FIV transfer between cat species has occurred in the past but is quite infrequent today. PMID:15956574

Descolonización y colonialismo interno: Lugar y función de lo colonial

Directory of Open Access Journals (Sweden)

Fernando Iturralde

2016-03-01

El siguiente artículo tiene como propósito indagar en la comprensión de aquello que es designado por el término “colonial” en tres intelectuales bolivianos: René Zavaleta Mercado, Silvia Rivera Cusicanqui y H.C.F. Mansilla. Encontramos, en los escritos de los tres, signos que nos permiten percibir una comprensión similar (aunque no la misma de lo que entienden por herencia colonial. En los tres casos, esa herencia es vista de forma peyorativa, es decir, como un rasgo que habría que poner de lado y finalmente erradicar. A partir de un análisis textual tratamos de comprender en qué consiste ese concepto o ese remanente colonial en estos tres autores. Una vez que logramos averiguar a qué se podrían referir estos autores cuando manejan la idea de una herencia colonial, analizamos y cuestionamos estas ideas a partir de la concepción que la teoría mimética tiene de conceptos similares. En otras palabras, buscamos traducir los conceptos de los pensadores bolivianos en términos de la teoría mimética, ya sea para comprenderlos mejor, ya sea para verificar si tienen una significación en el contexto de esa teoría.

[Population estimates and conservation of felids (Carnivora: Felidae) in Northern Quintana Roo, Mexico].

Science.gov (United States)

Ávila-Nájera, Dulce María; Chávez, Cuauhtémoc; Lazcano-Barrero, Marco A; Pérez-Elizalde, Sergio; Alcántara-Carbajal, José Luis

2015-09-01

Wildlife density estimates provide an idea of the current state of populations, and in some cases, reflect the conservation status of ecosystems, essential aspects for effective management actions. In Mexico, several regions have been identified as high priority areas for the conservation of species that have some level of risk, like the Yucatan Peninsula (YP), where the country has the largest population of jaguars. However, little is known about the current status of threatened and endangered felids, which coexist in the Northeastern portion of the Peninsula. Our objective was to estimate the wild cats' density population over time at El Eden Ecological Reserve (EEER) and its surrounding areas. Camera trap surveys over four years (2008, 2010, 2011 and 2012) were conducted, and data were obtained with the use of capture-recapture models for closed populations (CAPTURE + MMDM or 1/2 MMDM), and the spatially explicit capture-recapture model (SPACECAP). The species studied were jaguar (Panthera onca), puma (Puma concolor), ocelot (Leopardus pardalis), jaguarundi (Puma yaguaroundi) and margay (Leopardus wiedii). Capture frequency was obtained for all five species and the density for three (individuals/100km2). The density estimated with The Mean Maximum Distance Moved (MMDM), CAPTURE, ranged from 1.2 to 2.6 for jaguars, from 1.7 to 4.3 for pumas and from 1.4 to 13.8 for ocelots. The density estimates in SPACECAP ranged from 0.7 to 3.6 for jaguars, from 1.8 to 5.2 for pumas and 2.1 to 5.1 for ocelots. Spatially explicit capture recapture (SECR) methods in SPACECAP were less likely to overestimate densities, making it a useful tool in the planning and decision making process for the conservation of these species. The Northeastern portion of the Yucatan Peninsula maintains high populations of cats, the EEER and its surrounding areas are valuable sites for the conservation of this group of predators. Rev. Biol.

Las autoridades indígenas y los símbolos de prestigio

Directory of Open Access Journals (Sweden)

Cora Bunster

2001-01-01

Full Text Available El trabajo analiza el significado de los emblemas de poder y prestigio usados por las autoridades indígenas durante los siglos XVI y XVII, en el Virreinato del Perú. A través de los mismos los jefes étnicos legitiman su posición frente a la naciente sociedad colonial y ante sus propios ayllus. Se observan dos actitudes con respecto al uso de los mismos. Una es la adopción de formas pertenecientes a la cultura del colonizador ya que la integración de elementos foráneos es necesaria para la construcción y reconstrucción de la identidad y legitimidad cacicales. La otra es la utilización y alusión a símbolos de prestigio netamente andinos como vehículo de reafirmación de la identidad étnica local y como medio de lograr una jerarquización social frente al “otro” europeo en una sociedad en formación compuesta por españoles y andinos. Se examinan primero probanzas de mérito, reales cédulas y memoriales, cuyos protagonistas y/o autores son siempre señores étnicos que desean obtener algún beneficio material o de status social. Luego se analizan los cronistas andinos quienes mostraron en sus obras la naturaleza de la organización social de su pueblo, además de ser los primeros en expresar una crítica a la conquista. En ambos casos, sus autores hacen de la escritura un dispositivo decisivo para su reproducción e identidad como miembros de una elite

The role of landowners in jaguar conservation in Sonora, Mexico.

Science.gov (United States)

Rosas-Rosas, Octavio C; Valdez, Raul

2010-04-01

The northernmost known breeding population of jaguars occurs in the municipality of Nácori Chico, Sonora, Mexico about 270 km from the United States-Mexico border and may be the source from which jaguars sighted in the United States dispersed. Since 1999 at least 11 jaguars (Panthera onca) had been illegally killed in the area due to predator control programs. We initiated a jaguar landowner-based conservation plan in 2004. The eight participating landowners agreed to suspend predator control programs targeting jaguars and pumas (Puma concolor) only if cattle losses were compensated. A private outfitter, with the consent of landowners, initiated white-tailed deer (Odocoileus virginianus) hunts in 2004 and agreed to pay the group of participating landowners US$1500 for every deer hunt permit sold. The funds paid to the landowners from deer hunts were sufficient to convince landowners to suspend all predator-control efforts of jaguars and pumas. The involvement of landowners in the jaguar conservation program in northeastern Sonora is a successful, private, wildlife-conservation initiative that provides an example for jaguar conservation efforts in northern Mexico.

Músicas, movimientos, colores en la fiesta andina: ejemplos bolivianos

Directory of Open Access Journals (Sweden)

Rosalía Martínez

2014-01-01

Full Text Available En la fiesta andina, la música suele tanto oírse como verse. Esta dimensión multisensorial de la situación musical no es únicamente el resultado de una yuxtaposición de elementos sonoros y visuales. El análisis de las articulaciones que los campesinos indígenas de la zona de sucre (Bolivia construyen entre sonidos, movimientos y colores revela la presencia de organizaciones singulares de la experiencia sensible que se caracterizan tanto por su espesor sensorial como por la manera en la cual se encuentran conectadas con otros campos del conocimiento. Estas formas de intersección culturalmente elaboradas implican el cuerpo mismo de los músicos, generando nuevas configuraciones perceptivas.

La economía política de reformas institucionales en Bolivia

OpenAIRE

George Gray-Molina; Ernesto Perez de Rada; Ernesto Yáñez

1999-01-01

En este estudio analizamos el caso boliviano de reformas institucionales durante el periodo 1993-1997. Centramos la atención sobre tres reformas en particular: la Reforma de Participación Popular, la Reforma Educativa y la Reforma del Sistema de Pensiones. Cada una ejemplifica características singulares de cambio institucional tanto por el proceso como por los resultados de la adopción. La Participación Popular constituye uno de los intentos más ambiciosos de descentralización de los últimos ...

Adaptation aux changements climatiques et équité en Colombie rurale

International Development Research Centre (IDRC) Digital Library (Canada)

Articles de revue. Recent waves of water governance : constitutional reform and resistance to neoliberalization in Latin America (1990-2012); GEOFORUM (50: 20-30) - final version. Téléchargez le PDF. Documents. Equidad, eficiencia y escala en la asignación de agua en los países Andinos : sinergia o conflicto? 52993 ...

Vegetación halófila de tres localidades andinas en la vertiente pácifica del sur de perú

NARCIS (Netherlands)

Montesinos, D.B.

2012-01-01

Se describen las comunidades vegetales halófilas halladas en tres ecosistemas andinos en los departamentos de Arequipa y Moquegua (sur de Perú) en campos con influencia de pastoreo, fuego, abandono de agricultura o ocupando suelos inundados en las márgenes de los ríos. Se aplicó la metodología

The Andean Common Market: An Experiment in Regional Cooperation.

Science.gov (United States)

Carlson, Reynold E.

The Grupo Andino (GRAN) was formed in 1969 as an effort at economic integration by six Latin American countries (Bolivia, Chile, Columbia, Ecuador, Peru, and Venezuela). It was an outgrowth of its predecessor, the Latin American Free Trade Association (LAFTA), which had been formed in 1960 with eleven member countries. The Andean Group (GRAN) from…

Pilar García Jordán, El Estado propone, los c

OpenAIRE

Roux, Rodolfo de

2016-01-01

La autora, catedrática de historia de América en la Universidad de Barcelona, es una autoridad reconocida del mundo guarayo, al que ya ha dedicado cinco libros. En el último, que aquí reseñamos, reconstruye lo sucedido en quince años decisivos tanto para los guarayos como para la historia de la actual provincia de Guarayos, en el departamento boliviano de Santa Cruz. Pilar García comienza recordando que, en el contexto del surgimiento y desarrollo de Bolivia como Estado-nación, uno de los ret...

ENTRE LA COSTA DE COBIJA Y TIERRAS ALTAS: EL TRÁFICO ARRIERO A INICIOS DE LA REPÚBLICA BOLIVIANA

OpenAIRE

Letelier Cosmelli, Javiera

2016-01-01

Desde la configuración del Puerto de Cobija hasta la guerra del Pacífico, tanto indígenas como bolivianos y extranjeros establecieron relaciones en el marco de un contexto cambiante y complejo tanto a nivel nacional como internacional en donde se introduce la economía capitalista industrial. Es en ese marco que los arrieros y la movilidad entre costa y tierras altas se constituyeron en piezas claves para dar vida a Cobija y resto de Atacama. A partir de este escenario realizamos una revisión ...

Proceso histórico de reconocimiento de los derechos sociales en Bolivia: derecho a la educación

OpenAIRE

Corrales Dorado, Roberto Arturo

2015-01-01

La tesis tiene como temática central el lugar esencial que ocupa el derecho a la educación en el sistema constitucional boliviano de derechos fundamentales, con atención especial a los derechos sociales y, desde esta perspectiva, a la faceta prestacional del derecho a la educación. Sin lugar a dudas, de entrada, debe destacarse la actualidad permanente del tema elegido pues, en efecto, el conocimiento del ordenamiento constitucional, sea en términos de suscitar adhesión a los valores demo...

Los medios de comunicación masiva en conflicto: Reflexiones sobre el papel del periodismo en la situación boliviana / Mass media in conflict. Thoughts on the role of journalism in the bolivian situation

OpenAIRE

Torrico-Villanueva, Erick R.; Universidad Simón Bolívar (Bolivia)

2009-01-01

Los medios masivos bolivianos atraviesan una crisis de credibilidad atribuible a su politización, su frecuente recurso al sensacionalismo y sus errores profesiona les. Estos rasgos se han enfatizado en la actual situación de reordenamiento democrático que se caracteriza por una intensa conflictividad. Los medios han pasado de ser narra dores a ser verdaderos actores de los conflictos, pero esta condición, debido al estado de polarización social y política que vive el país, también está convir...

Circadian transitions in radiation dose-dependent augmentation of mRNA levels for DNA damage-induced genes elicited by accurate real-time RT-PCR quantification

International Nuclear Information System (INIS)

Ishihara, Hiroshi; Tanaka, Izumi; Yakumaru, Haruko

2010-01-01

Molecular mechanisms of intracellular response after DNA-damage by exposure to ionizing radiation have been studied. In the case of cells isolated from living body of human and experimental animals, alteration of the responsiveness by physiological oscillation such as circadian rhythm must be considered. To examine the circadian variation in the response of p53-responsible genes p21, mdm2, bax, and puma, we established a method to quantitate their mRNA levels with high reproducibility and accuracy based on real-time reverse transcription polymerase chain reaction (RT-PCR) and compared the levels of responsiveness in mouse hemocytes after diurnal irradiation to that after nocturnal irradiation. Augmentations of p21 and mdm2 mRNA levels with growth-arrest and of puma mRNA before apoptosis were confirmed by time-course experiment in RAW264.7, and dose-dependent increases in the peak levels of all the RNA were shown. Similarly, the relative RNA levels of p21, mdm2, bax, and puma per glyceraldehyde-3-phosphate dehydrogenase (GAPDH) also increased dose-dependently in peripheral blood and bone marrow cells isolated from whole-body-irradiated mice. Induction levels of all messages reduced by half after nighttime irradiation as compared with daytime irradiation in blood cells. In marrow cells, nighttime irradiation enhanced the p21 and mdm2 mRNA levels than daytime irradiation. No significant difference in bax or puma mRNA levels was observed between nighttime and daytime irradiation in marrow cells. This suggests that early-stage cellular responsiveness in DNA damage-induced genes is modulated between diurnal and nocturnal irradiation. (author)

Novel approach to abuse the hyperactive K-Ras pathway for adenoviral gene therapy of colorectal cancer

International Nuclear Information System (INIS)

Naumov, Inna; Kazanov, Dina; Lisiansky, Victoria; Starr, Alex; Aroch, Ilan; Shapira, Shiran; Kraus, Sarah; Arber, Nadir

2012-01-01

Background: Functional activation of oncogenic K-Ras signaling pathway plays an important role in the early events of colorectal carcinogenesis (CRC). K-Ras proto-oncogene is involved in 35–40% of CRC cases. Mutations in the Ras gene trigger the transduction of proliferative and anti-apoptotic signals, even in the absence of extra cellular stimuli. The objective of the current study was to use a gene-targeting approach to kill human CRC cells selectively harboring mutated K-Ras. Results: A recombinant adenovirus that carries a lethal gene, PUMA, under the control of a Ras responsive promoter (Ad-Py4-SV40-PUMA) was used selectively to target CRC cells (HCT116, SW480, DLD1 and RIE-Ras) that possess a hyperactive Ras pathway while using HT29 and RIE cells as a control that harbors wild type Ras and exhibit very low Ras activity. Control vector, without the Ras responsive promoter elements was used to assess the specificity of our “gene therapy” approach. Both adenoviral vectors were assed in vitro and in xenograft model in vivo. Ad-Py4-SV40-PUMA showed high potency to induce ∼ 50% apoptosis in vitro, to abolish completely tumor formation by infecting cells with the Ad-Py4-SV40-PUMA prior xenografting them in nude mice and high ability to suppress by ∼ 35% tumor progression in vivo in already established tumors. Conclusions: Selective targeting of CRC cells with the activated Ras pathway may be a novel and effective therapy in CRC. The high potency of this adenoviral vector may help to overcome an undetectable micro metastasis that is the major hurdle in challenging with CRC.

FORRAJE Y GRANO DE HÍBRIDOS DE MAÍZ AMARILLOS PARA VALLES ALTOS DE MÉXICO

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Margarita Tadeo-Robledo

2012-01-01

Full Text Available El objetivo de este trabajo fue determinar la producción de grano y de forraje en híbridos trilineales amarillos. Se establecieron en el año 2009 tres experimentos, comparando híbridos trilineales amarillos con híbridos comerciales blancos y el híbrido Búho de Asgrow; dos experimentos en el Campo Experimental de Valle de México del INIFAP, donde se evaluó la productividad de grano y otro en la Facultad de Estudios Superiores Cuautitlán de la Universidad Nacional Autónoma de México, para evaluación de forraje a una densidad de 70 000 plantas/ha. El análisis combinado para rendimiento detectó diferencias altamente significativas para híbridos, sitios y la interacción híbridos x sitios. El coeficiente de variación fue de 17,7% y la media general de 7113 kg/ha. La comparación de medias ubicó en el primer grupo de significancia a los híbridos de grano blanco comerciales Puma 1167 y Puma 1163 con 9549 kg/ha y 8748 kg/ha, respectivamente. Los híbridos amarillos 501X497 y 501X555 fueron superiores 36,0% y 12,4% con respecto a H-48 y el híbrido testigo. Búho presentó similar rendimiento en materia verde, que Puma 1163 y fue superior (P<0,05 a los otros híbridos evaluados. El híbrido Puma 1163 por su buen rendimiento de grano, materia verde y materia seca se sugiere validarlo a nivel comercial en doble propósito.

Novel approach to abuse the hyperactive K-Ras pathway for adenoviral gene therapy of colorectal cancer

Energy Technology Data Exchange (ETDEWEB)

Naumov, Inna [Integrated Cancer Prevention Center, Tel Aviv (Israel); Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (Israel); Kazanov, Dina [Integrated Cancer Prevention Center, Tel Aviv (Israel); Lisiansky, Victoria [Integrated Cancer Prevention Center, Tel Aviv (Israel); Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (Israel); Starr, Alex [Lung and Allergy Institute, Tel Aviv Sourasky Medical Center, Tel Aviv (Israel); Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (Israel); Aroch, Ilan; Shapira, Shiran; Kraus, Sarah [Integrated Cancer Prevention Center, Tel Aviv (Israel); Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (Israel); Arber, Nadir, E-mail: narber@post.tau.ac.il [Integrated Cancer Prevention Center, Tel Aviv (Israel); Department of Gastroenterology, Tel Aviv Sourasky Medical Center, Tel Aviv (Israel); Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv (Israel)

2012-01-15

Background: Functional activation of oncogenic K-Ras signaling pathway plays an important role in the early events of colorectal carcinogenesis (CRC). K-Ras proto-oncogene is involved in 35-40% of CRC cases. Mutations in the Ras gene trigger the transduction of proliferative and anti-apoptotic signals, even in the absence of extra cellular stimuli. The objective of the current study was to use a gene-targeting approach to kill human CRC cells selectively harboring mutated K-Ras. Results: A recombinant adenovirus that carries a lethal gene, PUMA, under the control of a Ras responsive promoter (Ad-Py4-SV40-PUMA) was used selectively to target CRC cells (HCT116, SW480, DLD1 and RIE-Ras) that possess a hyperactive Ras pathway while using HT29 and RIE cells as a control that harbors wild type Ras and exhibit very low Ras activity. Control vector, without the Ras responsive promoter elements was used to assess the specificity of our 'gene therapy' approach. Both adenoviral vectors were assed in vitro and in xenograft model in vivo. Ad-Py4-SV40-PUMA showed high potency to induce {approx} 50% apoptosis in vitro, to abolish completely tumor formation by infecting cells with the Ad-Py4-SV40-PUMA prior xenografting them in nude mice and high ability to suppress by {approx} 35% tumor progression in vivo in already established tumors. Conclusions: Selective targeting of CRC cells with the activated Ras pathway may be a novel and effective therapy in CRC. The high potency of this adenoviral vector may help to overcome an undetectable micro metastasis that is the major hurdle in challenging with CRC.

Nerve growth factor reduces apoptotic cell death in rat facial motor neurons after facial nerve injury.

Science.gov (United States)

Hui, Lian; Yuan, Jing; Ren, Zhong; Jiang, Xuejun

2015-01-01

To assess the effects of nerve growth factor (NGF) on motor neurons after induction of a facial nerve lesion, and to compare the effects of different routes of NGF injection on motor neuron survival. This study was carried out in the Department of Otolaryngology Head & Neck Surgery, China Medical University, Liaoning, China from October 2012 to March 2013. Male Wistar rats (n = 65) were randomly assigned into 4 groups: A) healthy controls; B) facial nerve lesion model + normal saline injection; C) facial nerve lesion model + NGF injection through the stylomastoid foramen; D) facial nerve lesion model + intraperitoneal injection of NGF. Apoptotic cell death was detected using the terminal deoxynucleotidyl transferase dUTP nick end-labeling assay. Expression of caspase-3 and p53 up-regulated modulator of apoptosis (PUMA) was determined by immunohistochemistry. Injection of NGF significantly reduced cell apoptosis, and also greatly decreased caspase-3 and PUMA expression in injured motor neurons. Group C exhibited better efficacy for preventing cellular apoptosis and decreasing caspase-3 and PUMA expression compared with group D (pfacial nerve injury in rats. The NGF injected through the stylomastoid foramen demonstrated better protective efficacy than when injected intraperitoneally.

Los 'Colorados': Etnohistoria y Toponimia

NARCIS (Netherlands)

Gómez-Rendón, J.

2015-01-01

Los "colorados" comprendían varios grupos étnicos emparentados etnolingüísticamente que ocupaban el piedemonte andino occidental desde El Carchi hasta Bolívar así como las tierras bajas del Pacífico en los sistemas hidrográficos de los ríos Esmeraldas y Guayas. Aunque la ocupación "colorada" de

Kaolin clays from Patagonia - Argentina. Relationship between the mineralogy and ceramic properties; Arcillas caolinicas de la Patagonia argentina. Relacion entre la mineralogia y las propiedades ceramicas

Energy Technology Data Exchange (ETDEWEB)

Factorovich, J.C.; Badino, D. [Piedra Grande S.A., Buenos Aires (Argentina); Cravero, F.; Dominguez, E. [Universidad Nacional del Sur, Bahia Blanca (Argentina). Dept. de Geologia

1997-12-31

The mineralogy, grain size distribution, chemical composition, S and C contents, plasticity, and cationic exchange capacity are determined in the sedimentary kaolinitic clays from the clay pits Puma Negra, Puma Gris, Tincar Super; and Chenque and Cardenal located in Santa Cruz and Chubut Provinces. Mineralogy and Particle size distribution of > 5, 5-2 and <2{mu} fractions are determined. Modulus of rupture, 1100 and 1250 deg C shrinkage and water absorption and whiteness are found. It is accomplished a statistics correlation between the characteristics of grain size distribution, mineralogy, and other physical properties with the main ceramic properties to understand its influence in the ceramic process. (author) 5 refs., 2 tabs.

Data of expression status of miR- 29a and its putative target mitochondrial apoptosis regulatory gene DRP1 upon miR-15a and miR-214 inhibition

Directory of Open Access Journals (Sweden)

Muhammad Ishtiaq Jan

2018-02-01

Full Text Available Data is about the mitochondrial apoptosis regulatory framework genes PUMA, DRP1 (apoptotic, and ARC (anti-apoptotic analysis after the employment of their controlling miRNAs inhibitors. The data represents putative conserved targeting of seed regions of miR-15a, miR-29a, and miR-214 with respective target genes PUMA, DRP1, and ARC. Data is of cross interference in expression levels of one miRNA family, miR-29a and its putative target DRP1 upon the inhibitory treatment of other miRNAs 15a and 214. Keywords: DRP1, miR-15a, Apoptosis, miRNAs inhibition

Kaolin clays from Patagonia - Argentina. Relationship between the mineralogy and ceramic properties

International Nuclear Information System (INIS)

Factorovich, J.C.; Badino, D.; Cravero, F.; Dominguez, E.

1997-01-01

The mineralogy, grain size distribution, chemical composition, S and C contents, plasticity, and cationic exchange capacity are determined in the sedimentary kaolinitic clays from the clay pits Puma Negra, Puma Gris, Tincar Super; and Chenque and Cardenal located in Santa Cruz and Chubut Provinces. Mineralogy and Particle size distribution of > 5, 5-2 and <2μ fractions are determined. Modulus of rupture, 1100 and 1250 deg C shrinkage and water absorption and whiteness are found. It is accomplished a statistics correlation between the characteristics of grain size distribution, mineralogy, and other physical properties with the main ceramic properties to understand its influence in the ceramic process. (author)

Carbono almacenado en páramo andino

OpenAIRE

Castañeda-Martín, Abel Efrén; Montes-Pulido, Carmen Rosa

2017-01-01

RESUMEN A pesar de la importancia del ecosistema de páramo en el ciclo global de carbono no se dispone de una síntesis que permita diferenciar si es la biomasa vegetal o el suelo el componente que acumula la mayor cantidad de carbono. En este documento se busca integrar los aspectos fundamentales relacionados con el carbono almacenado en el ecosistema de páramo, a través de: 1) Revisar las estimaciones de carbono en biomasa aérea y suelo reportadas por la literatura para el ecosistema de pára...

Genetic differences between mestizo populations of Bolivia and Peru

Directory of Open Access Journals (Sweden)

2003-01-01

plus grand assortiment de type caucasien chez les métisses péruviens rapportés dans la littérature. Ces découvertes pourraient avoir un impact en ce qui concerne l’efficacité de moyens d’immunisation modernes grâce aux vaccins d'ADN sur la population andine, et aussi en ce qui concerne l’identification de groupes à risque pour certaines conditions médicales. DIFERENCIAS GENÉTICAS ENTRE POBLACIONES MESTIZAS DE BOLIVIA Y PERÚ. Existe escasa información acerca del fondo genético de las poblaciones de Perú y Bolivia. Estudios han mostrado que los mestizos presentan varios alelos del sistema mayor de histocompatibilidad originalmente descritos en tribus amerindias genéticamente aisladas, y que los mestizos de Perú y Bolivia están genéticamente cercanamente relacionados. Mediante la técnica de transferencia de línea reversa, se realizó la tipificación de alelos de histocompatibilidad de Clase I (HLA-A, HLA-B, HLA-Cw así como de Clase II (HLA-DRB1 y HLA-DQB1 en 57 mestizos bolivianos. Los sujetos provinieron mayormente de La Paz (la ciudad principal en los Andes Bolivianos, además de otras tres ciudades importantes situadas en el Valle Central Boliviano (Sucre, Tarija y Tupiza. La comparación de la frecuencia de los alelos de los mestizos bolivianos con datos disponibles de la literatura acerca de mestizos peruanos, reveló que los alelos de Clase I HLA-Cw*01, y B*40 se encontraban en mayor proporción en el grupo de mestizos peruanos (Chi-cuadrado = 4.87 p<0,05 y chi-cuadrado = 7,56 p<0,01 respectivamente. Con respecto a los alelos de clase II, HLA-DRB1*1101 y DRB1*1302 se encontraron en mayor frecuencia en los mestizos peruanos (Chi-cuad = 5,12 p<.05 y chi-cuad = 3,8 p = 0.05 respectivamente, mientras que el alelo HLA-DQB1*0402 fue significativamente mayor en los mestizos bolivianos (Chi-cuad = 47,2 p<.0001. Las diferencias en las frecuencias de alelos encontradas, y la ausencia o presencia de algunos alelos en cualesquiera de los grupos, puede

Andean contributions to the biogeochemistry of the amazon river system

Directory of Open Access Journals (Sweden)

1995-01-01

Full Text Available LA CONTRIBUTION ANDINE A LA BIOGEOCHIMIE DE L’AMAZONE. Les fleuves andins ont vraisemblablement un rôle déterminant sur la biogéochimie de l’Amazone au Brésil. Les données disponibles sur le C organique, le NO3- et le PO43- des fleuves andins montrent des concentrations très variables et ne révèlent aucune relation avec leur altitude ou leur position dans le bassin. En général, les concentrations des fleuves andins sont semblables à celles du chenal principal et de ses principaux affluents. L’explication des phénomènes d’altération du matériel provenant des Andes ne peut être que spéculative. Cependant, l’atténuation du signal andin est liée à la décomposition et à l’ajout de matériel en aval des Andes. Les analyses de 13C sur la matière organique particulaire ou soluble du chenal principal de l’Amazone mettent en évidence qu’une fraction andine persiste dans le système fluvial qui se jette dans l’océan Atlantique. En 1994, un nouveau programme international de recherche a commencé pour mieux caractériser la biogéochimie des fleuves andins. CONTRIBUCIÓN ANDINA A LA BIOGEOQUÍMICA DEL RÍO AMAZONAS. Los ríos andinos podrían ejercer una influencia significativa sobre la biogeoquímica del Río Amazonas. Las concentraciones en C orgánico, NO3- y PO43- de los ríos andinos son altamente variables y no presentan claros patrones geográficos o altitudinos. En general, las concentraciones presentan valores similares a aquéllos observados en el Río Amazonas. Actualmente sólo existen explicaciones especulativas de los procesos que modifican el material de origen andino sin embargo, la atenuación de la señal andina es una consecuencia del proceso de descomposición y de la añadidura de materiales provenientes de las planicies bajas. El contenido de 13C en el material orgánico del Río Amazonas constituye una evidencia concreta de que cierta fracción del material andino persiste y es transportado hacia el

Mineralizations of the Lavalleja Group (Uruguay), a Probable Neoproterozoic Volcano-sedimentary Sequence

International Nuclear Information System (INIS)

Sanchez Bettucci, L.; Oyhantcabal, P.; Loureiro, J.; Basei, M.; Ramos, V.; Preciozzi, F.; Basei, M.

2004-01-01

The Lavalleja Group is located in the southern extreme of the Dom Feliciano Belt, being tentatively correlated with the Porongos and Brusque Groups of Brazil. The basement of the Lavalleja Group is probably represented by granitic gneissic rocks of the Campanero Unit with ages, in the southern portion, ranging from 1.75 to 2.1 Ga (U-Pb in zircon). The Lavalleja Group is characterized by narrow bands of meta sedimentary and meta volcanic rocks and it is separated in three formations, namely (from base to top): Zanja del Tigre, Fuente del Puma and Minas. Outcrops assigned to the Minas Formation have been recently correlated with the Arroyo del Soldado Group. Only the Fuente del Puma formation hosts base metals, Au and Ag occurrences. The Fuente del Puma formation is divided into three informal units: sedimentary, volcanic and hornblenditic gabbros. The sedimentary unit is characterized by an important amount of carbonates. Syn collisional to pos tectonic granitic bodies (Carapé Complex) intrudes the Lavalleja Group and the Campanero Unit. Several mineralizations are located in the Fuente del Puma Formation, those associated to Arrospide, Ramallo-Reus, Chape, Valencia, La Oriental, Apolonia, Redondo Hill, La China and La Paloma mines are the most important. In addition, many occurrences of Cu-Zn-Pb were recognized in the region. The Cu-Zn-Pb mineralization includes massive sulfides with pyrite-chalcopyrite-sphalerite-galena-pyrrothyte, arsenopyrite-hematite into small bodies with lenticular shape. The host rock shows frequently hydrothermal alteration. The geochemistry and the geological features of the mineralizations suggest Besshi Massive Sulphide Zn-Cu-Pb and SEDEX Zn-Pb as most probably genetic models for the deposits related to the Neoproterozoic orogeny. Early mineralizations are syngenetic and were formed on the sea floor, although the main mineralizations are related to remobilization during syn- to late-metamorphic events and thrusting

Camera traps as a tool for Carnivore conservation in a mosaic of Protected Areas in the Pantanal wetlands, Brazil

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Grasiela Porfirio

2018-06-01

Full Text Available Although known globally for its biodiversity, only around 5% of the Brazilian Pantanal is protected. The Network for Protection and Conservation of Amolar Mountain Ridge is an informal initiative that legally protects over 2000 km2 of the Pantanal biome. Several camera-trapping surveys were carried out at Amolar Mountain Ridge from August 2011 to September 2013 in order to increase our knowledge of the species occurrence and its ecological requirements. The aims of this study were : 1 to inventory the carnivore species occurring within this network of protected areas; 2 to describe their activity patterns and 3 to discuss threats for those species' conservation in the region. We used the Kernel density method to describe the species' activity patterns. We obtained 764 records (from 12703 camera-days of eight carnivores, including endangered species in Brazil, such as the jaguar (Panthera onca, puma (Puma concolor, and ocelot (Leopardus pardalis, that were among the most frequently recorded by camera traps. The other species detected were the South America coati (Nasua nasua, the tayra (Eira barbara, the crab-eating raccoon (Procyon cancrivorus and the jaguarundi (Puma yagouaroundi. We provided information on activity patterns of the jaguar and puma, which exhibited cathemeral activity patterns, on the ocelot and crab-eating fox, which were mostly nocturnal, and on the Southern coati and jaguarundi, which were diurnal. Scansorial and species that occur naturally in low densities as the tayra and the crab-eating raccoon were difficult to be detected with the used camera trapping setting. However, due to the natural characteristics of the study area, camera trapping is among the most appropriate tools for providing data about carnivores and their prey. This information is essential to delineate conservation plans for Amolar Mountain Ridge.

Immunity: Insect Immune Memory Goes Viral.

Science.gov (United States)

Ligoxygakis, Petros

2017-11-20

Adaptive memory in insect immunity has been controversial. In this issue, Andino and co-workers propose that acquisition of viral sequences in the host genome gives rise to anti-sense, anti-viral piRNAs. Such sequences can be regarded as both a genomic archive of past infections and as an armour of potential heritable memory. Copyright © 2017 Elsevier Ltd. All rights reserved.

La geografía diferencial de los derechos: entre la regulación del trabajo forzado en los países coloniales y la disociación entre trabajadores e indígenas en los Andes (1920-1954)

NARCIS (Netherlands)

Barragàn, R.; Caruso, Laura; Stagnate, Andrés

2017-01-01

En los países andinos de Perú, Ecuador y Bolivia, los indígenas podían representar entre el 60 y hasta el 90% de su población; vivían relativamente autónomos en comunidades, pero cuando lo hacían en haciendas se encontraban sujetos a relaciones laborales descritas bajo diversos grados de

Distribución espacio-temporal de larvas de Chironomidae (Diptera en un arroyo andino (Uspallata, Mendoza, Argentina Spatial and temporal distribution of larvae of Chironomidae (Diptera in an Andean stream (Uspallata, Mendoza, Argentina

Directory of Open Access Journals (Sweden)

Erica E. Scheibler

2008-12-01

Full Text Available Se realizó un estudio sobre la composición larval de la familia Chironomidae en un arroyo andino en la localidad de Uspallata (Mendoza, Argentina. Se realizaron muestreos estacionales durante un ciclo anual completo (2001/2002 en tres sitios, siguiendo un gradiente altitudinal. Se midieron variables físico-químicas en campo y laboratorio. La relación entre presencia y abundancia de quironómidos y parámetros ambientales se exploró mediante un análisis de Correspondencia Canónica. Se identificaron siete géneros pertenecientes a cuatro subfamilias: Chironominae, Orthocladiinae, Podonominae y Tanypodinae. Orthocladiinae fue la subfamilia que tuvo mayor riqueza genérica (Cricotopus van der Wulp, Onconeura Andersen & Saether y Parametriocnemus Goetghebuer, densidad y frecuencia de aparición a nivel estacional y espacial. Podonominae (Podonomus Philippi y Podonomopsis Brundin se halló únicamente en SA mientras que Chironominae (Polypedilum Kieffer estuvo presente en UD. Tanypodinae (Pentaneura Philippi se encontró en los tres sitios de muestreo aunque con una densidad menor. Se detectó incremento de la conductividad y temperatura del agua, y disminución del tamaño del sustrato desde SA a UD, lo que coincide con la desaparición de Podonomus y Podonomopsis y la aparición de Polypedilum hacia UD. De este estudio se concluye que el sistema presenta baja riqueza genérica comparada con otros sistemas montañosos de Argentina.A study was conducted on the larval composition of the family Chironomidae in an Andean stream in Uspallata locality (Mendoza, Argentina. Seasonal samplings were performed over a full annual cycle (2001/2002 at three sites, along an altitudinal gradient. Physical and chemical variables were measured in both the field and the laboratory. Relationship between presence and abundance of chironomids and environmental parameters was explored using a Canonical Correspondence analysis. Seven genera were identified

El proceso constitucional boliviano: dos visiones de país

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Miguel A. Buitrago

2014-06-01

Full Text Available Reflexión a  propósito del proceso constitucional iniciado por el presidente de Bolivia, Evo Morales, con un discurso el 22 de enero de 2006, en el cual se pretendía incluir a todos los grupos sociales y étnicos que habitaran el país para refundar la identidad boliviana.

Salar de Surire un ecosistema altoandino en peligro, frente a escenario del cambio climático

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Ingrid Garcés

2011-12-01

Full Text Available Este trabajo realiza un análisis al salar de Surire desde el punto de vista de la biodiversidad y sus implicancias producto del cambio climático. Como resultado se predice que los próximos años serán secos y la temperatura podría ir en aumento, lo cual afectará notablemente a la flora y fauna del altiplano. El salar de Surire es un cuerpo salino ubicado en el altiplano andino chileno, en un entorno geológico de características volcánicas. La climatología actual de aridez no permite una acumulación de agua superficial de gran extensión, y por lo tanto es posible diferenciar tres tipos principales de aguas: los aportes de drenaje, las acumulaciones de agua en la aureola pantanosa externa o “bofedales”, y las aguas del interior del cuerpo salino (surgencias termales y salmueras. Estas condiciones hidrológicas afectan factores abióticos, como anaerobiosis de suelos, disposición de nutrientes y salinidad, factores determinantes del desarrollo de la flora y fauna. Palabras claves: Salar de Surire; Biodiversidad andina; Cambio climático; Ecosistema andino

INVENTARIO DE MAMÍFEROS EN UN BOSQUE DE LOS ANDES CENTRALES DE COLOMBIA

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SÁNCHEZ FRANCISCO

2004-06-01

Full Text Available Se usaron técnicas de captura, observación directa y registro indirecto para obtenerun inventario de mamíferos en un bosque andino de Colombia. Se realizaronmuestreos entre octubre de 1998 y abril de 1999 en la Reserva Río Blanco (Manizales,Departamento de Caldas, entre 2200 - 3750 m de altitud. Para capturar pequeñosmamíferos no voladores se usaron trampas Sherman. Para capturar murciélagos seusaron mallas de niebla y colectas manuales. Para registrar medianos y grandesmamíferos se usaron trampas Tomahawk, puntos de observación, recorridos, trampasde huellas, rastros y encuestas. Se registraron 42 especies de mamíferospertenecientes a doce órdenes. El inventario de pequeños mamíferos no voladoresy murciélagos es incompleto; se dan sugerencias para complementarlo. Las trampasde huellas, los rastros y las encuestas fueron técnicas más eficientes para registrarmedianos y grandes mamíferos, que la captura con trampas Tomahawk, los recorridosy los puntos de observación. Se hacen observaciones y se dan recomendacionespara implementar las diferentes técnicas en bosques andinos.

Alfonso Gumucio-Dagron : más allá de la euforia tecnológica

OpenAIRE

Melo, José Marques de

2011-01-01

El autor presenta una síntesis del pensamiento del comunicador boliviano y su propuesta acerca de la comunicación para el cambio social, partiendo de la historia del pensamiento comunicacional latinoamericano y ubicando al autor en la línea de tiempo de influencia y de evolución académica e investigativa en América Latina. O autor apresenta uma síntese da pensamento e propostas sobre a comunicacão para a mudança social, do Alfonso Gumucio Dagron, baseada na história do pensamento latino-am...

Patrones reproductivos en la altura: ¿hipoxia o regulación cultural?

OpenAIRE

Crognier, Emile; Villena, M.; Vargas, E.

2001-01-01

Descripción de las características reproductivas en la altura basada en los datos recogidos en 1988-99 en 10 comunidades Aymará que viven a una altura promedio de 4000m en el Altiplano Boliviano. Se registraron las historias reproductivas de 868 mujeres casadas, la población femenina total, de las cuales 359 tenían entre 45 años y mas. El modelo reproductivo se presenta con un comienzo tardío de la fertilidad, y un comienzo tardío de los embarazos, asociado con un corto periodo reproductivo y...

Plutonium and Minor Actinide Management in Thermal High-Temperature Gas-Cooled Reactors. Publishable Final Activity Report

International Nuclear Information System (INIS)

Kuijper, J.C.; Somers, J.; Van Den Durpel, L.

2013-01-01

The PUMA project - the acronym stands for “Plutonium and Minor Actinide Management in Thermal High-Temperature Gas-Cooled Reactors” - was a Specific Targeted Research Project (STREP) within the Euratom 6th Framework (EU FP6). The PUMA project ran from September 1, 2006, until August 31, 2009, and was executed by a consortium of 14 European partner organisations and one from the USA. This report serves 2 purposes. It is both the 'Publishable Final Activity Report' and the 'Final (Summary) Report', describing, per Work Package, the specific objectives, research activities, main conclusions, recommendations and supporting documents. PUMA's main objective was to investigate the possibilities for the utilisation and transmutation of plutonium and especially minor actinides in contemporary and future (high temperature) gas-cooled reactor designs, which are promising tools for improving the sustainability of the nuclear fuel cycle. This contributes to the reduction of Pu and MA stockpiles, and also to the development of safe and sustainable reactors for CO2-free energy generation. The PUMA project has assessed the impact of the introduction of Pu/MA-burning HTRs at three levels: fuel and fuel performance (modelling), reactor (transmutation performance and safety) and reactor/fuel cycle facility park. Earlier projects already indicated favourable characteristics of HTRs with respect to Pu burning. So, core physics of Pu/MA fuel cycles for HTRs has been investigated to study the CP fuel and reactor characteristics and to assure nuclear stability of a Pu/MA HTR core, under both normal and abnormal operating conditions. The starting point of this investigation comprised the two main contemporary HTR designs, viz. the pebble-bed type HTR, represented by the South-African PBMR, and hexagonal block type HTR, represented by the GT-MHR. The results (once again) demonstrate the flexibility of the contemporary (and near future) HTR designs and their ability to accept a variety

Plutonium and Minor Actinide Management in Thermal High-Temperature Gas-Cooled Reactors. Publishable Final Activity Report

International Nuclear Information System (INIS)

Kuijper, J.C.; Somers, J.; Van Den Durpel, L.; Chauvet, V.; Cerullo, N.; Cetnar, J.; Abram, T.; Bakker, K.; Bomboni, E.; Bernnat, W.; Domanska, J.G.; Girardi, E.; De Haas, J.B.M.; Hesketh, K.; Hiernaut, J.P.; Hossain, K.; Jonnet, J.; Kim, Y.; Kloosterman, J.L.; Kopec, M.; Murgatroyd, J.; Millington, D.; Lecarpentier, D.; Lomonaco, G.; McEachern, D.; Meier, A.; Mignanelli, M.; Nabielek, H.; Oppe, J.; Petrov, B.Y.; Pohl, C.; Ruetten, H.J.; Schihab, S.; Toury, G.; Trakas, C.; Venneri, F.; Verfondern, K.; Werner, H.; Wiss, T.; Zakova, J.

2010-11-01

The PUMA project -the acronym stands for 'Plutonium and Minor Actinide Management in Thermal High-Temperature Gas-Cooled Reactors'- was a Specific Targeted Research Project (STREP) within the EURATOM 6th Framework Program (EU FP6). The PUMA project ran from September 1, 2006, until August 31, 2009, and was executed by a consortium of 14 European partner organisations and one from the USA. This report serves 2 purposes. It is both the 'Publishable Final Activity Report' and the 'Final (Summary) Report', describing, per Work Package, the specific objectives, research activities, main conclusions, recommendations and supporting documents. PUMA's main objective was to investigate the possibilities for the utilisation and transmutation of plutonium and especially minor actinides in contemporary and future (high temperature) gas-cooled reactor designs, which are promising tools for improving the sustainability of the nuclear fuel cycle. This contributes to the reduction of Pu and MA stockpiles, and also to the development of safe and sustainable reactors for CO 2 -free energy generation. The PUMA project has assessed the impact of the introduction of Pu/MA-burning HTRs at three levels: fuel and fuel performance (modelling), reactor (transmutation performance and safety) and reactor/fuel cycle facility park. Earlier projects already indicated favourable characteristics of HTRs with respect to Pu burning. So, core physics of Pu/MA fuel cycles for HTRs has been investigated to study the CP fuel and reactor characteristics and to assure nuclear stability of a Pu/MA HTR core, under both normal and abnormal operating conditions. The starting point of this investigation comprised the two main contemporary HTR designs, viz. the pebble-bed type HTR, represented by the South-African PBMR, and hexagonal block type HTR, represented by the GT-MHR. The results (once again) demonstrate the flexibility of the contemporary (and near future) HTR designs and their ability to accept a

Plutonium and Minor Actinide Management in Thermal High-Temperature Gas-Cooled Reactors. Publishable Final Activity Report

Energy Technology Data Exchange (ETDEWEB)

Kuijper, J.C., E-mail: kuijper@nrg.eu [Nuclear Research and Consultancy Group (NRG), Petten (Netherlands); Somers, J; Van Den Durpel, L; Chauvet, V; Cerullo, N; Cetnar, J; Abram, T; Bakker, K; Bomboni, E; Bernnat, W; Domanska, J G; Girardi, E; De Haas, J B.M.; Hesketh, K; Hiernaut, J P; Hossain, K; Jonnet, J; Kim, Y; Kloosterman, J L; Kopec, M; Murgatroyd, J; Millington, D; Lecarpentier, D; Lomonaco, G; McEachern, D; Meier, A; Mignanelli, M; Nabielek, H; Oppe, J; Petrov, B Y; Pohl, C; Ruetten, H J; Schihab, S; Toury, G; Trakas, C; Venneri, F; Verfondern, K; Werner, H; Wiss, T; Zakova, J

2010-11-15

The PUMA project -the acronym stands for 'Plutonium and Minor Actinide Management in Thermal High-Temperature Gas-Cooled Reactors'- was a Specific Targeted Research Project (STREP) within the EURATOM 6th Framework Program (EU FP6). The PUMA project ran from September 1, 2006, until August 31, 2009, and was executed by a consortium of 14 European partner organisations and one from the USA. This report serves 2 purposes. It is both the 'Publishable Final Activity Report' and the 'Final (Summary) Report', describing, per Work Package, the specific objectives, research activities, main conclusions, recommendations and supporting documents. PUMA's main objective was to investigate the possibilities for the utilisation and transmutation of plutonium and especially minor actinides in contemporary and future (high temperature) gas-cooled reactor designs, which are promising tools for improving the sustainability of the nuclear fuel cycle. This contributes to the reduction of Pu and MA stockpiles, and also to the development of safe and sustainable reactors for CO{sub 2}-free energy generation. The PUMA project has assessed the impact of the introduction of Pu/MA-burning HTRs at three levels: fuel and fuel performance (modelling), reactor (transmutation performance and safety) and reactor/fuel cycle facility park. Earlier projects already indicated favourable characteristics of HTRs with respect to Pu burning. So, core physics of Pu/MA fuel cycles for HTRs has been investigated to study the CP fuel and reactor characteristics and to assure nuclear stability of a Pu/MA HTR core, under both normal and abnormal operating conditions. The starting point of this investigation comprised the two main contemporary HTR designs, viz. the pebble-bed type HTR, represented by the South-African PBMR, and hexagonal block type HTR, represented by the GT-MHR. The results (once again) demonstrate the flexibility of the contemporary (and near future) HTR designs and their ability to accept a

Plutonium and Minor Actinide Management in Thermal High-Temperature Gas-Cooled Reactors. Publishable Final Activity Report

Energy Technology Data Exchange (ETDEWEB)

Kuijper, J.C., E-mail: kuijper@nrg.eu [Nuclear Research and Consultancy Group (NRG), Petten (Netherlands); Somers, J.; Van Den Durpel, L.; Chauvet, V.; Cerullo, N.; Cetnar, J.; Abram, T.; Bakker, K.; Bomboni, E.; Bernnat, W.; Domanska, J.G.; Girardi, E.; De Haas, J.B.M.; Hesketh, K.; Hiernaut, J.P.; Hossain, K.; Jonnet, J.; Kim, Y.; Kloosterman, J.L.; Kopec, M.; Murgatroyd, J.; Millington, D.; Lecarpentier, D.; Lomonaco, G.; McEachern, D.; Meier, A.; Mignanelli, M.; Nabielek, H.; Oppe, J.; Petrov, B.Y.; Pohl, C.; Ruetten, H.J.; Schihab, S.; Toury, G.; Trakas, C.; Venneri, F.; Verfondern, K.; Werner, H.; Wiss, T.; Zakova, J.

2010-11-15

The PUMA project -the acronym stands for 'Plutonium and Minor Actinide Management in Thermal High-Temperature Gas-Cooled Reactors'- was a Specific Targeted Research Project (STREP) within the EURATOM 6th Framework Program (EU FP6). The PUMA project ran from September 1, 2006, until August 31, 2009, and was executed by a consortium of 14 European partner organisations and one from the USA. This report serves 2 purposes. It is both the 'Publishable Final Activity Report' and the 'Final (Summary) Report', describing, per Work Package, the specific objectives, research activities, main conclusions, recommendations and supporting documents. PUMA's main objective was to investigate the possibilities for the utilisation and transmutation of plutonium and especially minor actinides in contemporary and future (high temperature) gas-cooled reactor designs, which are promising tools for improving the sustainability of the nuclear fuel cycle. This contributes to the reduction of Pu and MA stockpiles, and also to the development of safe and sustainable reactors for CO{sub 2}-free energy generation. The PUMA project has assessed the impact of the introduction of Pu/MA-burning HTRs at three levels: fuel and fuel performance (modelling), reactor (transmutation performance and safety) and reactor/fuel cycle facility park. Earlier projects already indicated favourable characteristics of HTRs with respect to Pu burning. So, core physics of Pu/MA fuel cycles for HTRs has been investigated to study the CP fuel and reactor characteristics and to assure nuclear stability of a Pu/MA HTR core, under both normal and abnormal operating conditions. The starting point of this investigation comprised the two main contemporary HTR designs, viz. the pebble-bed type HTR, represented by the South-African PBMR, and hexagonal block type HTR, represented by the GT-MHR. The results (once again) demonstrate the flexibility of the contemporary (and near future) HTR

Dihydroartemisinin induces apoptosis preferentially via a Bim-mediated intrinsic pathway in hepatocarcinoma cells.

Science.gov (United States)

Qin, Guiqi; Zhao, ChuBiao; Zhang, Lili; Liu, Hongyu; Quan, Yingyao; Chai, Liuying; Wu, Shengnan; Wang, Xiaoping; Chen, Tongsheng

2015-08-01

This report is designed to dissect the detail molecular mechanism by which dihydroartemisinin (DHA), a derivative of artemisinin, induces apoptosis in human hepatocellular carcinoma (HCC) cells. DHA induced a loss of the mitochondrial transmemberane potential (ΔΨm), release of cytochrome c, activation of caspases, and externalization of phosphatidylserine indicative of apoptosis induction. Compared with the modest inhibitory effects of silencing Bax, silencing Bak largely prevented DHA-induced ΔΨm collapse and apoptosis though DHA induced a commensurable activation of Bax and Bak, demonstrating a key role of the Bak-mediated intrinsic apoptosis pathway. DHA did not induce Bid cleavage and translocation from cytoplasm to mitochondria and had little effects on the expressions of Puma and Noxa, but did increase Bim and Bak expressions and decrease Mcl-1 expression. Furthermore, the cytotoxicity of DHA was remarkably reduced by silencing Bim, and modestly but significantly reduced by silencing Puma or Noxa. Silencing Bim or Noxa preferentially reduced DHA-induced Bak activation, while silencing Puma preferentially reduced DHA-induced Bax activation, demonstrating that Bim and to a lesser extent Noxa act as upstream mediators to trigger the Bak-mediated intrinsic apoptosis pathway. In addition, silencing Mcl-1 enhanced DHA-induced Bak activation and apoptosis. Taken together, our data demonstrate a crucial role of Bim in preferentially regulating the Bak/Mcl-1 rheostat to mediate DHA-induced apoptosis in HCC cells.

Ecological niche models and patterns of richness and endemism of the southern Andean genus Eurymetopum (Coleoptera, Cleridae Modelos de nicho ecológico y patrones de riqueza y endemismo del género andino austral Eurymetopum (Coleoptera, Cleridae

Directory of Open Access Journals (Sweden)

Tania Escalante

2009-01-01

Full Text Available Eurymetopum is an Andean clerid genus with 22 species. We modeled the ecological niches of 19 species with Maxent and used them as potential distributional maps to identify patterns of richness and endemicity. All modeled species maps were overlapped in a single map in order to determine richness. We performed an optimality analysis with NDM/VNDM in a grid of 1º latitude-longitude in order to identify endemism. We found a highly rich area, located between 32º and 41º south latitude, where the richest pixels have 16 species. One area of endemism was identified, located in the Maule and Valdivian Forest biogeographic provinces, which extends also to the Santiago province of the Central Chilean subregion, and contains four endemic species (E. parallelum, E. prasinum, E. proteus, and E. viride, as well as 16 non-endemic species. The sympatry of these phylogenetically unrelated species might indicate ancient vicariance processes, followed by episodes of dispersal. Based on our results, we suggest a close relationship between these provinces, with the Maule representing a complex area.Eurymetopum es un género de cléridos andinos con 22 especies. Modelamos los nichos ecológicos de 19 especies con Maxent y los utilizamos como mapas de distribución potencial para identificar patrones de riqueza y endemismo. Todos los mapas de las especies se superpusieron en un mapa único para determinar la riqueza. Realizamos un análisis de optimalidad con NDM/VNDM en una cuadrícula de 1º de latitud-longitud para identificar el endemismo. Hallamos un área de mayor riqueza, localizada entre los 32º y 41º de latitud sur, donde los pixeles más ricos poseen 16 especies. Se identificó un área de endemismo en las provincias biogeográficas del Maule y el Bosque Valdiviano, la cual se extiende también a la provincia de Santiago de la subregión Chilena Central, y que contiene cuatro especies endémicas (E. parallelum, E. prasinum, E. proteus y E. viride, as

Tracking cats: problems with placing feline carnivores on δO, δD isoscapes.

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Stephanie J Pietsch

Full Text Available Several felids are endangered and threatened by the illegal wildlife trade. Establishing geographic origin of tissues of endangered species is thus crucial for wildlife crime investigations and effective conservation strategies. As shown in other species, stable isotope analysis of hydrogen and oxygen in hair (δD(h, δ(18O(h can be used as a tool for provenance determination. However, reliably predicting the spatial distribution of δD(h and δ(18O(h requires confirmation from animal tissues of known origin and a detailed understanding of the isotopic routing of dietary nutrients into felid hair.We used coupled δD(h and δ(18O(h measurements from the North American bobcat (Lynx rufus and puma (Puma concolor with precipitation-based assignment isoscapes to test the feasibility of isotopic geo-location of felidae. Hairs of felid and rabbit museum specimens from 75 sites across the United States and Canada were analyzed. Bobcat and puma lacked a significant correlation between H/O isotopes in hair and local waters, and also exhibited an isotopic decoupling of δ(18O(h and δD(h. Conversely, strong δD and δ(18O coupling was found for key prey, eastern cottontail rabbit (Sylvilagus floridanus; hair and white-tailed deer (Odocoileus virginianus; collagen, bone phosphate.Puma and bobcat hairs do not adhere to expected pattern of H and O isotopic variation predicted by precipitation isoscapes for North America. Thus, using bulk hair, felids cannot be placed on δ(18O and δD isoscapes for use in forensic investigations. The effective application of isotopes to trace the provenance of feline carnivores is likely compromised by major controls of their diet, physiology and metabolism on hair δ(18O and δD related to body water budgets. Controlled feeding experiments, combined with single amino acid isotope analysis of diets and hair, are needed to reveal mechanisms and physiological traits explaining why felid hair does not follow isotopic patterns

Estimación poblacional y conservación de felinos (Carnivora: Felidae en el norte de Quintana Roo, México

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Dulce María Ávila-Nájera

2015-09-01

Full Text Available Resumen:La estimación de la densidad de fauna silvestre permite tener una idea del estado de salud de las poblaciones y en algunos casos indica el estado de conservación de los ecosistemas. Los métodos de evaluación deben hacer estimaciones no sesgadas, ya que servirán de base para estrategias de conservación de especies clave. Algunas regiones en México han sido identificadas como áreas de alta prioridad para la conservación de especies con cierto nivel de riesgo, como es la Península de Yucatán (PY, donde prevalece la mayor población de jaguares en México. Sin embargo, poco se sabe acerca de la situación actual de los felinos amenazados y en peligro de extinción, como un grupo de especies que conviven en la parte noreste de la Península. Nuestro objetivo fue estimar la densidad de las poblaciones de felinos silvestres a mediano plazo en la Reserva Ecológica El Edén (EEER y sus alrededores. Se llevaron a cabo muestreos con cámaras-trampa durante cuatro años (2008, 2010, 2011 y 2012, se usaron modelos de captura-recaptura para poblaciones cerradas (CAPTURA + MMDM o VMMDM y un modelo de C-R espacial-mente explícito (CERC por medio del paquete SPCACAP para realizar las estimaciones de densidad. Las especies estudiadas fueron: jaguar (Panthera onca,puma (Puma concolor,ocelote (Leopardus pardalis,jaguarundi (Puma yaguaroundiy tigrillo (Leopardus wiedii.La frecuencia de captura se obtuvo para las cinco especies y la densidad para tres (individuos/100km2. La densidad estimada por medio de MMDM varió entre 1.2 y 2.6 para jaguares, pumas (1.7-4.3 y ocelotes (1.4-13.8. Las estimaciones de la densidad en SPACECAP variaron desde 0.7 hasta 3.6 para jaguares, de 1.8 a 5.2 para pumas y de 2.1 a 5.1 en ocelotes. El método de C-R espacialmente explícito (SECR, SPACECAP tiene menos probabilidades de sobrestimar la densidad, lo que provee una herramienta útil en el proceso de planificación y toma de decisiones para la conservación de

Toxocariasis in Carnivora from Argentinean Patagonia: Species molecular identification, hosts, and geographical distribution

Directory of Open Access Journals (Sweden)

R.M. Vega

2018-04-01

Full Text Available Twenty four specimens of seven species belonging to the families Felidae, Mustelidae, and Canidae were obtained in Lanín and Nahuel Huapi National Parks from March 1996 to April 2016. Specimens were processed by necropsy in order to contribute to the knowledge of toxocariasis in wild carnivores of Argentinean Patagonia. The only Puma concolor and the seven Leopardus geoffroyi were positive for Toxocara cati. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP of the ITS-1 region from larval and adult DNA was carried out to confirm parasite species identification. This is the first molecular determination of T. cati from wild felids in Argentina and the study also fill gaps about the spatial distribution and hosts for Toxocara cati. Keywords: Toxocara cati, Puma concolor, Leopardus geoffroyi, Molecular identification, Argentina

Família e inserção laboral de jovens migrantes na indústria de confecção

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Patrícia Tavares de Freitas

Full Text Available Neste artigo, abordamos os percursos sociais de jovens bolivianos e bolivianas que, em algum momento de suas vidas, migraram para se inserir em pequenas oficinas de costura de seus compatriotas, nas cidades de São Paulo, no Brasil, e Buenos Aires, na Argentina. A análise, baseada em pesquisa de doutorado intitulada "Projeto costura", busca abordar os vários sentidos atribuídos ao papel da família em suas formas de inserção, circulação e saída dessa atividade nas cidades de destino e na própria Bolívia.

Los primeros pasos de una ciencia republicana emancipatoria en la América andina

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Leoncio LÓPEZ-OCÓN

2011-07-01

Full Text Available En este artículo se muestran, en primer lugar, las diversas acciones realizadas por los gobiernos de los países andinos en las primeras décadas de vida independiente para fomentar el cultivo de las ciencias. Entre esas acciones cabe destacar la promoción de la enseñanza técnica, la importación de científicos de Europa y el apoyo dado a los naturalistas europeos que recorrieron las nuevas naciones andinas siguiendo las huellas de Alejandro de Humboldt. Se analiza luego el debate entre los historiadores sobre si ese impulso científico inicial se debió a la iniciativa de los propios países andinos o surgió de presiones procedentes del extranjero. Se señalan finalmente algunos resultados de los programas de investigación de naturalistas y médicos en las repúblicas andinas durante el segundo tercio del siglo XIX. Se sostiene entonces que debido a esa multiplicidad de iniciativas se estableció en la América andina, y en otras partes del continente americano, un vínculo duradero y decisivo entre ciencia y política, entre saber y poder.

Toidupoolis Säästumarketist, riided Kreisimarketist

Index Scriptorium Estoniae

2005-01-01

2005. a. alguses tekkis Eestisse uus riiete säästukauplus, kus müüakse tuntud kaubamärkide nagu Puma, Nike, Adidas jt. tooteid umbes poole odavamalt kui tavakauplustes. Vt. samas: Hinnapommi juhtum

CRONICA: FIESTA FUNERAL: LUMBALÚ PARA BATA III

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Enrique Luis Muñoz Vélez

2005-08-01

Full Text Available El trabajo se inspira en las conversaciones con Paulino Salgado Valdez. Entrevistas con Batata III en Bogotá, 1998 y en Cartagena en el 2000 en el marco del Encuentro de los países andinos. Batata III nace el 29 de mayo de 1927 en el Palenque de San Basilio en el departamento de Bolívar, muere en Bogotá el viernes 23 de enero del 2004.

Modulation of the Proliferation and Metastasis of Human Breast Tumor Cells by SLUG (IDEA)

National Research Council Canada - National Science Library

Chaudhuri, Gautam

2007-01-01

.... They include cytokeratins 8, 18, and 19, E-cadherin, occludin, Na/K ATPase, vitamin D receptor, integrin alpha 3, PUMA, BRCA2, claudins 5, 3, 7, 11, 1, 14, and 16, desmoglein 1, and 2, PCNA, PGDH...

The effects of demographic, social, and environmental characteristics on pathogen prevalence in wild felids across a gradient of urbanization.

Directory of Open Access Journals (Sweden)

Jesse S Lewis

Full Text Available Transmission of pathogens among animals is influenced by demographic, social, and environmental factors. Anthropogenic alteration of landscapes can impact patterns of disease dynamics in wildlife populations, increasing the potential for spillover and spread of emerging infectious diseases in wildlife, human, and domestic animal populations. We evaluated the effects of multiple ecological mechanisms on patterns of pathogen exposure in animal populations. Specifically, we evaluated how ecological factors affected the prevalence of Toxoplasma gondii (Toxoplasma, Bartonella spp. (Bartonella, feline immunodeficiency virus (FIV, and feline calicivirus (FCV in bobcat and puma populations across wildland-urban interface (WUI, low-density exurban development, and wildland habitat on the Western Slope (WS and Front Range (FR of Colorado during 2009-2011. Samples were collected from 37 bobcats and 29 pumas on the WS and FR. As predicted, age appeared to be positively related to the exposure to pathogens that are both environmentally transmitted (Toxoplasma and directly transmitted between animals (FIV. In addition, WS bobcats appeared more likely to be exposed to Toxoplasma with increasing intraspecific space-use overlap. However, counter to our predictions, exposure to directly-transmitted pathogens (FCV and FIV was more likely with decreasing space-use overlap (FCV: WS bobcats and potential intraspecific contacts (FIV: FR pumas. Environmental factors, including urbanization and landscape covariates, were generally unsupported in our models. This study is an approximation of how pathogens can be evaluated in relation to demographic, social, and environmental factors to understand pathogen exposure in wild animal populations.

Transmutation of radioactive nuclear waste – present status and ...

Indian Academy of Sciences (India)

Transmutation of long-lived actinides and fission products becomes an im- ... Similar approach was performed for sub critical fast reactor core with Pu/MA .... The same might be addressed to masses of nuclei (the use of experimental values.

Telerobotics in hazardous environments

International Nuclear Information System (INIS)

Bicker, R.; Glennie, D.; Ow, S.M.

1996-01-01

A bilateral force reflecting telerobotic system has been developed that allows the slave robot to be operated either manually, as in a conventional teleoperator system, or autonomously as a sensor driven robot. The implementation of shared control provides additional functionality which permits the operator to manually control the position (and/or velocity) of selected axes, whilst the remaining axes are controlled autonomously, using active force control. The force control scheme utilizes an active compliance algorithm to maintain the slave end-effector in contact with the workpiece at a prescribed force (or torque) along selected axes. The control system architecture is based on a network of parallel processors. A Puma 260 robot has been adapted as a force reflecting generalised manual input device and a Puma 760 robot has been configured to operate using force control as the slave robot. (UK)

Iconografía religiosa andina en el noroeste argentino

Directory of Open Access Journals (Sweden)

1986-01-01

Full Text Available L'examen du 'Disque de Lafone Quevedo ou Disque de Chaquiago' s'inscrit dans deux perspectives: l'importance de l'étude de l'histoire des Andes méridionales et l'andin comme unité dynamique. Une telle analyse nous permet de faire des rapprochements intéressants: ainsi, sont mis en évidence des liens entre les disques et les plaques de bronze du Nord de l'Argentine et de Bolivie, la vision de Pachacutec (le promoteur de l'expansion Inca et l'image principale (Punchao du Coricancha. Enfin, de nouveaux éléments sont proposés en faveur de l'existence d'une divinité polyvalente dont la longue histoire rassemble les 'récits sacrés' de plusieurs dieux andins. El examen del 'Disco de Lafone Quevedo o Disco de Chaquiago' está enmarcado dentro de dos perspectivas: la importancia del estudio de la historia de los Andes meridionales y 'lo andino' como unidad dinámica. Su análisis nos permite señalar correspondencias interesantes. Así, se hallarán evidencias que establezcan las vinculaciones entre los discos y placas de bronce del NO. argentino y Bolivia, la visión de Pachacuti (que dio origen a la expansión de los Incas y la imagen principal (Punchao del Coricancha. Para finalizar, se propone nuevos elementos en favor de la existencia de una deidad polivalente en cuya larga historia se recoge las 'historias sagradas' de varios dioses andinos. The examination of the 'Disc of Lafone Quevedo or Disc of Chaquiago' is inscribed in two perspectives: the importance of the study of the history of the meridional Andes and lo andino as a dynamic unit. Such an analysis permits us to make interesting comparisons: thus are placed on evidence links between the discs and the bronze plaques from the North of Argentina and Bolivia, the vision of Pachacutec (the instigator of the Inca expansion and the principal image (Punchao of the Coricancha. Finally, new elements are proposed in favor of the existence of a polyvalent divinity of which the long history

CRUZANDO LOS MALLKUS. LAS MIGRACIONES BOLIVIANAS PENDULARES DURANTE LAS GRANDES CRISIS SALITRERAS (1914 - 1933

Directory of Open Access Journals (Sweden)

Sergio González Miranda

2011-10-01

Full Text Available Este artículo analiza el proceso migratorio pendular de la población boliviana (especialmente indígena hacia las salitreras de Tarapacá; destacándose la “gran crisis” de 1930 y años siguientes, analizando el desarraigo del retorno a Bolivia. Se sostiene que a partir del término de la Primera Guerra Mundial se inicia la decadencia del ciclo de expansión del salitre, generando procesos migratorios de atracción y expulsión de mano de obra, donde el drama social producto de la cesantía fue el factor común. En otras palabras, se plantea que la crisis del salitre no surgió en la década de los años treinta, como suele reconocerse en la literatura especializada sobre la industria salitrera, sino a partir de la primera guerra mundial se inicia el proceso de decadencia del mercado mundial del nitrato, siendo la década de los años veinte cuando se define el futuro de esta industria. Se estudia, especialmente a través de la prensa y archivos oficiales, los sistemas de enganche, los flujos de ida y venida de trabajadores bolivianos con sus familias, especialmente durante los años de crisis entre 1914 y 1933, donde el drama de la cesantía afectó a miles de bolivianos que debieron regresar a sus comunidades de origen. Este artículo se enmarca dentro de un análisis histórico que rescata la importancia de la sociedad civil en las relaciones entre países fronterizos, como Bolivia y Chile, fenómeno que la disciplina de las relaciones internacionales denomina acertadamente “paradiplomacia”.

Contra-reforma y des-constitucionalización estatal en Bolivia: Del horizonte plurinacional a la restauración neocolonial del Estado-nación

Directory of Open Access Journals (Sweden)

Pabel Camilo López Flores

2017-12-01

Full Text Available Los sentidos y contenidos transformadores del actual texto Constitucional boliviano, como resultado de un polémico proceso constituyente que se realizó en la década pasada con la densidad de una ‘coyuntura fundante’, a pesar de haber sido objeto de negociaciones y modificaciones por actores del poder constituido, resulto en un texto que representaba un horizonte de cambio en torno a la construcción de un Estado Plurinacional. Sin embargo, luego de su aprobación y promulgación, normas sucesivas y políticas estatales y gubernamentales que tiene lugar en la realidad del país apuntarían a un retroceso de los horizontes de transformación estatal de la Constitución y a un evidente proceso de contra-reforma y des-constitucionalización, lo que alejarían cada vez más la construcción plurinacional del Estado y, por el contrario, reproducen y acentúan una faceta monológica del Estado-nación en Bolivia. En este breve texto se propone un abordaje al actual contexto sociopolítico del proceso post-constituyente boliviano en la década actual y una mirada crítica a la situación del horizonte de construcción del Estado plurinacional a través de las orientaciones e implicaciones de las políticas del gobierno del MAS en lo últimos años de manejo estatal, que expresarían, entre otros aspectos, un proceso de des-constitucionalizacion, una tendencia de desplurinacionalizacion del Estado con efectos en la relación del Estado con las organizaciones sociales comunitarias, los pueblos indígenas y con sus reivindicaciones.

Incidencia de los Hábitos Alimenticios en los Niveles de Rendimiento Académico Escolar en las Instituciones Educativas Secundarias Urbano Marginales de Juliaca

OpenAIRE

Aguilar Roque, Gaylee Yemira

2015-01-01

El presente trabajo de investigación denominado “INCIDENCIA DE LOS HÁBITOS ALIMENTICIOS EN LOS NIVELES DE RENDIMIENTO ACADÉMICO ESCOLAR EN LAS INSTITUCIONES EDUCATIVAS SECUNDARIAS URBANO - MARGINALES DE JULIACA”, cuyo objetivo general es establecer la importancia del consumo de cereales andinos y productos procesados en los niveles de rendimiento académico de los estudiantes de las I.E.S. de las zonas urbano – marginales de la ciudad de Juliaca. Este estudio nos permite establec...

Gumucio-Dagron: más allá de la euforia tecnológica

Directory of Open Access Journals (Sweden)

José Marques de Melo

2011-12-01

Full Text Available Alfonso Gumucio-Dagron se destaca en la comunidad de las ciencias de la comunicación por su fidelidad orgánica al pensamiento latinoamericano, reconocido mundialmente por el compromiso que tiene con el cambio social. Navegando contra viento y marea, este ícono boliviano protagonizó recientemente un hecho que tiene significado histórico: lideró el proceso de difusión del pensamiento crítico en esta coyuntura de euforia tecnológica y de olvido de la memoria popular. Estos y otros aportes al campo de la comunicación han sido importantes para fortalecer la mística latinoamericana en este cruce de signos ultraglobalizantes y de planteos neonacionalistas.

Tráfico de Pessoas para fins de exploração do trabalho na cidade de São Paulo Human trafficking for labour exploitation in the city of São Paulo

Directory of Open Access Journals (Sweden)

Paulo Illes

2008-12-01

Full Text Available Este artigo busca contextualizar, em linhas gerais, o fluxo de imigrantes bolivianos para fins de trabalho nas oficinas de costura da cidade de São Paulo, demonstrando a interface dessa imigração com o tráfico de migrantes e o tráfico de pessoas. Por meio de depoimentos, são apresentadas as recorrentes dificuldades enfrentadas pelas trabalhadoras imigrantes.This article seeks to contextualize, along general lines, the Bolivian migratory flow towards sweatshops in the city of São Paulo, showing the interaction between this migratory flow, migrant smuggling and human trafficking. The most frequent problems faced by the migrant women are presented in testimonials.

Pathogen exposure varies widely among sympatric populations of wild and domestic felids across the United States

Science.gov (United States)

Carver, Scott; Bevins, Sarah N.; Lappin, Michael R.; Boydston, Erin E.; Lyren, Lisa M.; Alldredge, Mathew W.; Logan, Kenneth A.; Sweanor, Linda L.; Riley, Seth P.D.; Serieys, Laurel E.K.; Fisher, Robert N.; Vickers, T. Winston; Boyce, Walter M.; McBride, Roy; Cunnigham, Mark C.; Jennings, Megan; Lewis, Jesse S.; Lunn, Tamika; Crooks, Kevin R.; VandeWoude, Sue

2016-01-01

Understanding how landscape, host, and pathogen traits contribute to disease exposure requires systematic evaluations of pathogens within and among host species and geographic regions. The relative importance of these attributes is critical for management of wildlife and mitigating domestic animal and human disease, particularly given rapid ecological changes, such as urbanization. We screened >1,000 samples from sympatric populations of puma (Puma concolor), bobcat (Lynx rufus) and domestic cat (Felis catus) across urban gradients in six sites, representing three regions, in North America for exposure to a representative suite of bacterial, protozoal and viral pathogens (Bartonella sp., Toxoplasma gondii, feline herpesvirus-1, feline panleukopenea virus, feline calicivirus, feline immunodeficiency virus). We evaluated prevalence within each species, and examined host trait and land cover determinants of exposure-providing an unprecedented analysis of factors relating to potential for infections in domesticated and wild felids. Prevalence differed among host species (highest for puma and lowest for domestic cat) and was greater for indirectly transmitted pathogens. Sex was inconsistently predictive of exposure to directly transmitted pathogens only, and age infrequently predictive of both direct and indirectly transmitted pathogens. Determinants of pathogen exposure were widely divergent between the wild felid species. For puma, suburban landuse predicted increased exposure to Bartonella sp. in southern California, and FHV-1 exposure increased near urban edges in Florida. This may suggest inter-specific transmission with domestic cats via flea vectors (California) and direct contact (Florida) around urban boundaries. Bobcats captured near urban areas had increased exposure to T. gondii in Florida, suggesting an urban source of prey. Bobcats captured near urban areas in Colorado and Florida had higher FIV exposure, possibly suggesting increased intra

Agrupaciones de cuidadores familiares en Colombia: perfil, habilidad de cuidado y sobrecarga

Directory of Open Access Journals (Sweden)

Sonia Patricia Carreño

2017-01-01

Full Text Available Objetivo. Explorar el papel de las variables sociodemográfi cas, la sobrecarga del cuidador y la habilidad de cuidado en una muestra de cuidadores de personas con enfermedad crónica en Colombia, para conocer sus formas de agrupación. Método. Se empleó un diseño cuantitativo, de corte descriptivo. La muestra estuvo constituida por 1137 cuidadores familiares, quienes respondieron la Encuesta de Caracterización de la Diada (cuidador-paciente, el Inventario de Habilidad de Cuidado de Nkongho y la Encuesta de Sobrecarga de Zarit. Con estos datos se realizó un análisis factorial y un análisis de conglomerados k-medias. Resultados.Se encontró que los cuidadores se agrupan según su región de procedencia, en cuatro conjuntos geográfi cos: andino y pacífi co, andino, caribe y amazónico. Además, se observó que cada agrupación posee necesidades de atención específi cas para el cuidador. Conclusión. Los grupos de cuidadores identifi cados refl ejan la diversidad cultural del país y la urgencia de explorar factores socioculturales que pueden estar incidiendo en las habilidades de cuidado y de sobrecarga de los cuidadores, según su región de procedencia.

Detection of Toxolasma gondii in captive wild felids.

Science.gov (United States)

Buddhirongawatr, Ruangrat; Tungsudjai, Siriporn; Chaichoune, Kridsada; Sangloung, Charoonluk; Tantawiwattananon, Nitipan; Phonaknguen, Rassameepen; Sukthana, Yaowalark

2006-01-01

Toxoplasma gondii can infect all species of warm-blooded animals, including humans, and causes serious diseases in immunocompromized hosts. Live tachyzoites derived from serial passage in HeLa culture were used in the Sabin-Feldman dye test for detection of Toxoplasma gondii antibody in serum samples of 21 captive wild felids including one fishing cat (Prion nailurus viverrina), one leopard (Panthera pardus), two flat-headed cats (Prion nailurus planiceps), 6 tigers (Panthera tigris), two leopard cats (Felis bengalensis), two clouded leopards (Felis nebulosa), 3 pumas (Puma concolor), and 4 jungle cats (Felis chaus). Antibodies to Toxoplasma gondii were founded in 9 of 21 felids (42.8%). This study revealed that cell culture-derived tachyzoites can be used successfully as a source of live organisms in a gold standard Sabin-Feldman dye test, which is simpler, cheaper and less ethically sensitive than in vivo inoculation.

Java interface for asserting interactive telerobotic control

Science.gov (United States)

DePasquale, Peter; Lewis, John; Stein, Matthew R.

1997-12-01

Many current web-based telerobotic interfaces use HyperText Markup Language (HTML) forms to assert user control on a robot. While acceptable for some tasks, a Java interface can provide better client-server interaction. The Puma Paint project is a joint effort between the Department of Computing Sciences at Villanova University and the Department of Mechanical and Materials Engineering at Wilkes University. THe project utilizes a Java applet to control a Unimation Puma 1760 robot during the task of painting on a canvas. The interface allows the user to control the paint strokes as well as the pressure of a brush on the canvas and how deep the brush is dipped into a paint jar. To provide immediate feedback, a virtual canvas models the effects of the controls as the artist paints. Live color video feedback is provided, allowing the user to view the actual results of the robot's motions. Unlike the step-at-a-time model of many web forms, the application permits the user to assert interactive control. The greater the complexity of the interaction between the robot and its environment, the greater the need for high quality information presentation to the user. The use of Java allows the sophistication of the user interface to be raised to the level required for satisfactory control. This paper describes the Puma Paint project, including the interface and communications model. It also examines the challenges of using the Internet as the medium of communications and the challenges of encoding free ranging motions for transmission from the client to the robot.

La influencia positiva de la CAN en la descentralización territorial colombiana

OpenAIRE

Ruth Carolina Blanco Alvarado

2015-01-01

Mediante las presentes páginas desarrollaremos la importancia del proceso andino de integración en la descentralización territorial colombiana. Para efectos de lo anterior, estableceremos, desde una perspectiva general, los principales beneficios que la descentralización territorial colombiana puede obtener en el marco de la Comunidad Andina (CAN), haciendo un análisis que descarta la perspectiva económica, núcleo rector de cualquier proceso de integración, y como consecuencia de ello, pre...

El acuerdo de comercio preferencial entre la Unión Europea, Colombia y Perú. Contenido y cambios al Status quo

OpenAIRE

Dieter Wolfram

2011-01-01

El acuerdo de comercio preferencial negociado y suscrito entre la Unión Europea, Colombia y Perú en mayo de 2010 aspira a profundizar y vivificar las relaciones comerciales entre las partes sin causar conflictos con convenciones internacionales multilaterales como el GATT, el GATS, el ADPIC, y la Convención sobre la Biodiversidad. . Un análisis de los cambios jurídicos impulsados por el acuerdo muestra pocas modificaciones o cambios sustanciales del status quo. Para los comerciantes andinos, ...

Equivalence of velocity-level and acceleration-level redundancy-resolution of manipulators

International Nuclear Information System (INIS)

Cai Binghuang; Zhang Yunong

2009-01-01

The equivalence of velocity-level and acceleration-level redundancy resolution of robot manipulators is investigated in this Letter. Theoretical analysis based on gradient-descent method and computer simulations based on PUMA560 robot manipulator both demonstrate the equivalence of redundancy-resolution schemes at different levels.

Estudio de la variabilidad genética en camélidos bolivianos

OpenAIRE

Barreta Pinto, Julia

2013-01-01

El estudio de los camélidos sudamericanos es de gran interés en los países andinoscomo Perú, Bolivia, Chile, Argentina, debido a su importante valor económico y suimportancia en el mantenimiento y desarrollo de las poblaciones rurales en dichos países. Dada la falta de estudios genéticos centrados en las poblaciones de camélidos quehabitan en Bolivia, y la necesidad de realizar una valoración de la diversidad genética deestas poblaciones, la presente Tesis doctoral ha abordado el estudio gené...

Roving UAV IED Interdiction System

Science.gov (United States)

2011-03-01

UAVs (Raven, Wasp, and Puma) do not advertise any payload capability, the Tier I operators that Team Bravo contacted claimed small payload...www.ncca.navy.mil/services/inflation.cfm (accessed February 2011). Net Resources International. "Javelin Anti- Armour Missile." Army-Technology.com. 2011. http

Second Generation Dutch Pulsar Machine - PuMa-II

NARCIS (Netherlands)

Karuppusamy, Ramesh; Stappers, Ben; Slump, Cornelis H.; van der Klis, Michiel

2004-01-01

The Second Generation Pulsar Machine (PuMa- II) is under development for the Westerbork Synthesis Radio Telescope. This is a summary of th e system design and architecture. We show that state of the art pulsar research is possible with commercially available hardware components. This approach

Prevention of immunodeficiency virus induced CD4+ T-cell depletion by prior infection with a non-pathogenic virus

International Nuclear Information System (INIS)

TerWee, Julie A.; Carlson, Jennifer K.; Sprague, Wendy S.; Sondgeroth, Kerry S.; Shropshire, Sarah B.; Troyer, Jennifer L.; VandeWoude, Sue

2008-01-01

Immune dysregulation initiated by a profound loss of CD4+ T-cells is fundamental to HIV-induced pathogenesis. Infection of domestic cats with a non-pathogenic lentivirus prevalent in the puma (puma lentivirus, PLV or FIV PCO ) prevented peripheral blood CD4+ T-cell depletion caused by subsequent virulent FIV infection. Maintenance of this critical population was not associated with a significant decrease in FIV viremia, lending support to the hypothesis that direct viral cytopathic effect is not the primary cause of immunodeficiency. Although this approach was analogous to immunization with a modified live vaccine, correlates of immunity such as a serum-neutralizing antibody or virus-specific T-cell proliferative response were not found in protected animals. Differences in cytokine transcription profile, most notably in interferon gamma, were observed between the protected and unprotected groups. These data provide support for the importance of non-adaptive enhancement of the immune response in the prevention of CD4+ T-cell loss

Comparing the personality of three well-known sporting brands in Iran

Directory of Open Access Journals (Sweden)

Mohmood Mohammadian

2012-08-01

Full Text Available A significant amount of literature specifies that there are benefits for having a favorable brand personality, such as purchase intentions and enhanced brand attitudes and higher degrees of consumer trust and loyalty. Brand differentiation is one of most important issues to handle competition in the hostile marketplace. A reliable solution for establishing the distinctiveness of a brand is through brand personality. This study analyzes the personality of Adidas, Nike and Puma brands in Iran using Aaker,s brand personality dimensions [Aakar (1997. Dimensions of brand personality. Journal of Marketing Resources, 24, 347–356]. First, data are collected using a questionnaire designed based on Aaker,s model. Second, the K-S and Friedman tests are done to analyze the collected data. Results indicate that in terms of sincerity and competence, Adidas scores are higher than two other brands. Nike in point of view of excitement, and Puma in terms of sophisticated and ruggedness dimensions have higher position in comparison to other brands.

Composición bioquímica y toxicidad de colonias comestibles de la cianobacteria andina Nostoc sp. Llayta

OpenAIRE

Galetovic, Alexandra; E. Araya, Jorge; Gómez-Silva, Benito

2017-01-01

RESUMEN Llayta es el nombre asignado a la biomasa seca de macrocolonias de una cianobacteria filamentosa, clasificada como Nostoc sp. Llayta crece en humedales andinos de Sudamérica y ha sido considerada como un ingrediente alimenticio desde tiempos precolombinos. Este estudio pretende contribuir a la definición de la calidad nutritiva de la Llayta, proporcionando información sobre su composición bioquímica e identificar aspectos críticos de interés toxicológico. Los resultados mostraron que ...

Asociaciones políticas de inmigrantes peruanos y la "Lima Chica" en Santiago de Chile

OpenAIRE

Luque Brazán, José Carlos

2007-01-01

El presente trabajo describe y examina la emergencia y desarrollo de tres asociaciones políticas de inmigrantes peruanos y su relación con el surgimiento de un "vecindario cultural", conocido por sus habitantes, la prensa chilena y algunos investigadores como la "Lima Chica", en Santiago de Chile. Nos referimos al Comité de Refugiados Peruanos en Chile, a la Asociación de Inmigrantes por la Integración Latinoamericana y del Caribe (APILA) y al Programa Andino para la Dignidad Humana (Proandes...

Cuando los muiscas diversificaron la agricultura y crearon el intercambio

Directory of Open Access Journals (Sweden)

Carl Henrik Langebaek

1985-02-01

Full Text Available Al comienzo del siglo XVI y de la conquista del centro de la actual Colombia, los españoles encontraron un grupo indígena, los muiscas, que habitaban en los valles interandinos fríos y en las tierras adyacentes de la cordillera Oriental. Su territorio abarcaba una amplia porción del ramal andino, desde los páramos de Sumapaz, al sur, hasta el valle transversal del Chicamocha, al norte, en los actuales departamentos de Cundinamarca y Boyacá.

Composición química de “oca” (Oxalis tuberosa), ‘arracacha’ (Arracaccia xanthorriza) y ‘tarwi’ (Lupinus mutabilis). Formulación de una mezcla base para productos alimenticios

OpenAIRE

Sandra Elizabeth Pagador Flores; Misael Ydilbrando Villacorta González; María Elena León Marroú

2011-01-01

El presente trabajo tuvo como objetivo formular una mezcla base a partir de cultivos nativos, la cual una vez estandarizada, se constituye en materia prima de alto valor nutricional para su utilización en la elaboración de productos alimenticios como: purés, papillas y productos de panificación, entre otros. Se seleccionaron tres cultivos andinos: un tubérculo, “oca” (Oxalis tuberosa); una raíz, ‘arracacha’ (Arracaccia xanthorriza) y una leguminosa, ‘tarwi’ (Lupinus mutabilis). Se realizaron ...

Desarrollo de producto sobre la base de harinas de cereales y leguminosa para niños celíacos entre 6 y 24 meses; II: Propiedades de las mezclas

OpenAIRE

Cerezal Mezquita, P.; Urtuvia Gatica, V.; Ramírez Quintanilla, V.; Arcos Zavala, R.

2011-01-01

Las formulaciones alimenticias de alto contenido proteico, aportado por una mezcla de harinas a partir de dos cultivos andinos, quinua (Chenopodium quinua Willd) y lupino (Lupi-nus albus L), con dos cereales tradicionales maíz (Zea mays L.) y arroz (Oryza sativa L.), conllevaron a la preparación de una 'mezcla dulce' para la elaboración de queques y otra "mezcla postre" saborizada con plátano, que puede ser preparada con agua o con leche, constituyeron una buena alternativa como suplemento al...

Una base impermeabilizante de los populismos: Bolivia y su historia reciente

Directory of Open Access Journals (Sweden)

María Teresa Pinto Ocampo

2006-11-01

Full Text Available El artículo analiza la idea de la presencia de líderes populistas exitosos en Bolivia en años recientes. Desarrolla la idea de que en Bolivia no hay incentivos estructurales para que se desarrolle un líder populista debido al hecho de que los populistas no crecen en un contexto de extrema organización popular independiente. En la primera parte presenta una discusión sobre el marco teórico de la noción de populismo y de la definición del autor; la segunda parte presenta el caso del populismo boliviano analizando los elementos históricos que contribuyen a la ausencia del mismo hoy (especialmente el tipo de

Residential Segregation and Adequate Housing among Migrants from Bolivia and Peru in Córdoba, Argentina

Directory of Open Access Journals (Sweden)

Florencia MOLINATTI

2017-01-01

Full Text Available En gran parte de América Latina la segregación residencial ha sido abordada casi exclusivamente desde una perspectiva socioeconómica, siendo mucho menos frecuente su abordaje étnico. El objetivo de este trabajo es analizar la segregación de los migrantes bolivianos y peruanos que residen en la ciudad de Córdoba y su vinculación con el acceso a una vivienda adecuada, a partir de datos del Censo de 2010. Ambos grupos se encuentran segregados y en condiciones residenciales deficientes. Aunque el colectivo más segregado no presenta los peores indicadores habitacionales, es una paradoja que evidencia la compleja relación entre segregación y acceso a una vivienda adecuada.

Wild carnivores (Mammalia) as hosts for ticks (Ixodida) in Panama

NARCIS (Netherlands)

Bermudez, S.E.; Esser, H.J.; Miranda, R.; Moreno, R.S.

2015-01-01

This study reports ticks collected from wild carnivores from different habitat types in Panama. We examined 94 individual wild carnivores and we found 87 parasitized by ticks: seven coyotes, six crab-eating foxes, 54 coatis, four raccoons, five ocelots, two pumas, two gray foxes, two skunks, and one

Wild felids as hosts for human plague, Western United States

Science.gov (United States)

Bevins, S.N.; Tracey, J.A.; Franklin, S.P.; Schmit, V.L.; MacMillan, M.L.; Gage, K.L.; Schriefer, M.E.; Logan, K.A.; Sweanor, L.L.; Alldredge, M.W.; Krumm, C.; Boyce, W.M.; Vickers, W.; Riley, S.P.D.; Lyren, L.M.; Boydston, E.E.; Fisher, R.N.; Roelke, M.E.; Salman, M.; Crooks, K.R.; VandeWoude, S.

2009-01-01

Plague seroprevalence was estimated in populations pumas and bobcats in the western United States. High levels of exposure in plague-endemic regions indicate the need to consider the ecology and pathobiology of plague nondomestic felid hosts to better understand the role of these species in disease persistence and transmission.

Soccer jersey sponsors and the world cup

NARCIS (Netherlands)

Groot, L.F.M.; Ferwerda, J.

2014-01-01

The market for soccer jerseys is a multibillion market dominated by Adidas, Nike and Puma. This paper investigates whether jersey sponsorship has a non-arbitrary effect on the outcomes of World Cup knockout matches. The results show that in the knockout stages of the last four World Cup tournaments,

78 FR 54623 - Foreign-Trade Zone (FTZ) 7-Mayaguez, Puerto Rico; Notification of Proposed Production Activity...

Science.gov (United States)

2013-09-05

... the foreign status inputs noted below and in the existing scope of authority. Customs duties also..., 2013. Puma Energy already has authority to conduct certain standard refinery operations involving crude... to the scope of authority. Pursuant to 15 CFR 400.14(b), additional FTZ authority would be limited to...

Mammalian carnivore occupancy is inversely related to presence of domestic dogs in the high Andes of Ecuador.

Science.gov (United States)

Zapata-Ríos, Galo; Branch, Lyn C

2018-01-01

Although the Andes have long been occupied by people, habitat loss, fragmentation through deforestation, and other human activities such as introduction of invasive species have increased drastically during the past century. The Ecuadorian Andes are considered a biodiversity hotspot. However, the fauna and threats to the region are poorly studied, and understanding of factors that shape the distribution of species in habitats disturbed by human activities is needed to identify and mitigate region-wide threats to wildlife. We evaluated factors associated with patterns of occurrence of Andean carnivores in landscapes of the northern Ecuadorian Andes, particularly habitat loss, fragmentation, and occupancy of domestic dogs, and determined whether thresholds occurred for these factors beyond which carnivore occurrence declined markedly. Five study areas (each 20 x 20 km) were surveyed with a total effort of 2,800 camera trap nights. Occupancies of four of the eight carnivores known from the region were best predicted by occupancy of domestic dogs rather than measures of habitat loss and fragmentation [Andean fox (Pseudalopex culpaeus), puma (Puma concolor), striped hog-nosed skunk (Conepatus semistriatus), and Andean bear (Tremarctos ornatus)]. The two largest carnivores, puma and Andean bear, demonstrated significant threshold responses to the presence of domestic dogs at two sites. Four smaller carnivores were recorded too infrequently to model occupancy, and at least two of these species appear to be in decline. The magnitude of domestic dog impacts on native species in tropical areas like the Ecuadorian Andes currently are not recognized. Results of our study indicate that small and large carnivores are in urgent need of conservation and clearly point to dogs as a significant threat to a broad range of native species.

Desarrollo empresarial como eje transversal para la competitividad en el sector portuario Venezolano

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Ada Maritza Pérez Cárdenas

2014-01-01

Full Text Available El desarrollo Regional del Caribe Venezolano, está conformado por los principales puertos marítimos de Maracaibo, Puerto Cabello y La Guaira. Los cuales se encuentran ubicados en el eje Andino, que está constituido por cinco países: Bolivia, Ecuador, Colombia, Perú y Venezuela. Donde promocionan un sistema de coordinación para la planificación estratégica de la integración física y sincronización de las actividades de comercio internacional. El Eje Andino se caracteriza por articular los principales aeropuertos internacionales y los puertos marítimos de los cinco países. Originando esto un punto estratégico para las negociaciones internacionales y el desarrollo económico social y cultural para lograr un impacto en las funciones comerciales.En Venezuela sus principales centros urbanos, lo componen las ciudades de Caracas, Maracay, Valencia, Maracaibo, Puerto La Cruz, Barcelona, Ciudad Guayana y San Cristóbal. Dentro del eje andino Venezuela es el punto de enlace ferroviario de Caracas con la red nacional, así como brindar apoyo a la negociación comercial en el eje fluvial Orinoco Apure.Palabras Clave: Desarrollo; Eje Transversal; Punto de Enlace. Business development as cross shaft for competitiveness in the port sectorAbstractThe development of the Venezuelan Caribbean Regional, is formed by. major seaports Maracaibo Puerto Cabello and La Guaira. Which are located in the Andean axis, which is formed by five countries, Bolivia, Colombia, Peru and Venezuela. Which promoted a system of coordination for the strategic planning of the integration of physical and disincronizacion international trade activities. The Andean axis is characterized by articulating the major international airports and seaports of the five countries.Causing it a strategic point for international negotiations in Venezuela the main urban centers, it comprises the cities of Caracas, Maracay, Valencia, Maracaibo, Puerto La Cruz, Barcelona, Ciudad Guayana and

La crisis del ciclo neoliberal en los países de la región andina

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Eudis F. Fermín T.

2010-01-01

Full Text Available En el artículo se estudia la crisis del ciclo neoliberal en los países de la Región Andina en el contexto delos cambios políticos latinoamericanos. Es una investigación documental-analítica, fundamentada en una revisión bibliográfica y en la clasificación del material para el procesamiento de los datos recolectados, la interpretación de esos datos parte de la categoría crisis del ciclo neoliberal. El neoliberalismo reduce las funciones de los Estados andinos a las áreas medulares: educación, salud y seguridad ciudadana, privatiza las empresas estatales y los servicios públicos, donde la ¿razón del mercado¿ priva la relación Sociedad-Estado, con consecuencias nefastas para la población, originando en el tiempo el surgimiento democrático de gobiernos anti-neoliberales. Se concluye que en los albores del siglo XXI el neoliberalismo entra en crisis, cuando el mercado manifiesta su incapacidad de contrarrestar los altos índices de pobreza y el deterioro de las condiciones vida de los ¿pueblos¿, los gobiernos andinos de izquierda introducen cambios en los sistemas políticos, redimensionando las políticas de ajuste macro-económico y rechazan los acuerdos bilaterales y multilaterales promotores de libre mercado en el seno del sistema institucional de integración andina.

DIVERSITY OF SAPROTROPHIC ANAMORPHIC ASCOMYCETES FROM NATIVE FORESTS IN ARGENTINA: AN UPDATED REVIEW

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Natalia Allegrucci

2009-01-01

Full Text Available En Argentina se reconocen ocho regiones de bosques nativos: bosque Andino-Patagónico, Talares de la Región Pampeana, Parque Chaqueño, Selva Misionera, Selva Tucumano-Boliviana, Monte, Espinal y Bosques Pluviales de los ríos Paraguay, Paraná y Uruguay. El objetivo de este trabajo ha sido reunir y revisar la información sobre la biodiversidad de microhongos saprótrofos (Ascomycetes anamórficos citados en los bosques nativos de Argentina, desde las primeras colecciones de Spegazzini hasta el presente. De las regiones anteriormente mencionadas los bosques Andino-Patagónicos, Bosques Pluviales de los ríos Paraguay, Paraná y Uruguay y recientemente los Talares de la provincia de Buenos Aires son aquellos donde se han realizado más exploraciones de microhongos saprótrofos. Por otro lado se obtuvieron muy pocos registros de especies fúngicas del resto de los bosques; para la región de Monte en particular no se han realizado hasta el presente estudios de hongos anamórficos, por lo cual no se cuenta con registros de especies anamórficas de Ascomycetes. Como resultado de una revisión bibliográfica exhaustiva, se registraron 344 especies, de las cuales 81 (23,5% son nuevas especies. Este trabajo pone de manifiesto la falta de exploraciones de áreas de importancia en nuestro país, y muestra la necesidad de incrementar estos estudios.

Constitutively active ErbB2 regulates cisplatin-induced cell death in breast cancer cells via pro- and antiapoptotic mechanisms

DEFF Research Database (Denmark)

Sigurðsson, Haraldur H; Olesen, Christina Wilkens; Dybboe, Rie

2015-01-01

cancer cell death, and determine how NHE1 regulates this process. Cisplatin treatment elicited apoptosis, ATM phosphorylation, upregulation of p53, Noxa (PMAIP1), and PUMA (BBC3), and cleavage of caspase-9, -7, fodrin, and PARP-1 in MCF-7 cells. Inducible ΔNErbB2 expression strongly reduced cisplatin...

Exclusory and Transformative Dimensions of Adult Environmental Education in Two Brazilian Protected Areas

Science.gov (United States)

Valenti, Mayla Willik; de Oliveira, Haydée Torres; Logarezzi, Amadeu José Montagnini

2017-01-01

This study addresses the limitations and potential for the development of an adult environmental education program in two protected areas in Brazil. The investigation was based on critical communicative methodology and involved 25 people variously related to puma conservation and environmental education. We found that the staff of protected areas…

Antropometría del trabajador minero de la altura

OpenAIRE

Ramírez, Augusto V.

2013-01-01

Introducción: La antropometría trata de las medidas del cuerpo humano y es base fundamental para la ergonomía. La minería peruana se localiza casi siempre en la gran altura, hábitat del hombre andino, que tiene características antropométricas diversas al hombre del llano. Objetivo: Caracterizar antropométricamente a una población andina de trabajadores mineros en la sierra central del Perú. Diseño: El estudio fue descriptivo, tipo prospectivo y observacional. Lugar: Servicio de Salud Ocupacio...

Lo indio, indigenismo y movimiento campesino en el Perú

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Carlos Fernández Fontenoy

2013-07-01

Full Text Available En este artículo el autor presenta un análisis histórico sobre la naturaleza de la aparición de movimientos indígenas en Perú, en la segunda mitad del siglo XX. Se compara la situación del país andino, con otros de la región  y encuentra una relación con las especiales condiciones en las que se conforman los partidos políticos y se describe su dependencia con los movimientos sociales y campesinos.

Diagnóstico de los mecanismos de cooperación multilateral en materia antidroga referente a la reducción de oferta, donde participan los países de América del Sur: Marco de Recomendaciones para el Consejo Suramericano sobre el Problema Mundial de las Drogas

OpenAIRE

Agatón Posada, Ginna Paola

2013-01-01

Esta investigación diagnóstica tiene por objeto la elaboración de un marco de recomendaciones para el Consejo Suramericano sobre el Problema Mundial de Drogas con el fin de actuar frente al problema de las drogas en la región a partir del diagnóstico de los alcances y limitaciones de la Comisión Interamericana para el Control del Abuso de Drogas (CICAD) y la decisión 505 o Plan Andino de Cooperación para la Lucha contra las Drogas Ilícitas y Delitos Conexos.

Minería y glaciares rocosos: impactos ambientales, antecedentes políticos y legales, y perspectivas futuras

OpenAIRE

Brenning,Alexander; Azócar,Guillermo F

2010-01-01

El interés científico y político en los glaciares rocosos andinos ha aumentado fuertemente en los últimos años debido al creciente reconocimiento de su importancia hidrológica y las recientes intervenciones mineras en ellos. Se presenta un resumen de los conocimientos científicos y el marco político-legal de las intervenciones pasadas y actuales en glaciares rocosos en Chile y, en forma preliminar, en Argentina y Perú. En estos países, 26 faenas mineras han afectado glaciares rocosos o podría...

DEFORMACION CORTICAL Y PELIGRO SÍSMICO ASOCIADO A LA FALLA SAN RAMON EN EL FRENTE CORDILLERANO DE SANTIAGO, CHILE CENTRAL (33ºS)

OpenAIRE

RAULD PLOTT, RODRIGO ANDRES

2011-01-01

Resultados presentados recientemente, que se incluyen en esta tesis (Armijo, R., R. Rauld, R. Thiele, G. Vargas, J. Campos, R. Lacassin, and E. Kausel (2010), The West Andean Thrust (WAT), the San Ramón Fault and the seismic hazard for Santiago (Chile), Tectonics, 29, TC2007, doi:10.1029/2008TC002427) modifican substancialmente paradigmas anteriores sobre la tectónica Andina y la Geología de la región de Santiago, sosteniendo que: 1) El orógeno Andino es fundamentalmente bi-vergente, in...

Antropometría del trabajador minero de la altura

OpenAIRE

Augusto V Ramírez

2006-01-01

Introducción: La antropometría trata de las medidas del cuerpo humano y es base fundamental para la ergonomía. La minería peruana se localiza casi siempre en la gran altura, hábitat del hombre andino, que tiene características antropométricas diversas al hombre del llano. Objetivo: Caracterizar antropométricamente a una población andina de trabajadores mineros en la sierra central del Perú. Diseño: El estudio fue descriptivo, tipo prospectivo y observacional. Lugar: Servicio de Salud Ocupacio...

La escritura fonémica del quechua Ayacuchano

OpenAIRE

Majerhua Castro, Samuel

2008-01-01

El presente trabajo de investigación es el resultado de varios años de recopilación de datos concernientes a demostrar que en el mundo andino hay una diversidad de lenguas y dialectos que continúan vertiginosamente atomizándose producto de la presencia compulsiva de la política etnocentrista de la cultura occidental, quien genera en los Andes la barrera lingüística y la discriminación social y cultural. En el caso de la lengua quechua, el factor fundamental de la profunda dialectalizació...

Sistemas de gestión de seguridad y salud en el trabajo en la comunidad andina : auditorías de verificación

OpenAIRE

Vásquez Zamora, Luis

2016-01-01

Objetivos: análisis comparativo de los principales sistemas de gestión de seguridad y salud tomando como referente el Sistema de la Comunidad Andina. Elaborar un sistema de auto auditorías automatizado y comparar sus resultados con auditorías externas realizadas por expertos del Instituto Ecuatoriano de la Seguridad Social (IESS) y conocer el grado de aceptación de empresarios y trabajadores de! sistema de auditorías. Metodología: Se comparó el sistema Andino, vigente en los países de Colo...

Análisis de la Cooperación Multilateral para la Gestión de biodiversidad en Instituciones Subregionales. Caso de Estudio: Estrategia regional para la conservación y uso Sostenible de recursos en el Amazonas (TCA) y Proyecto Facilitación de financiamiento para negocios de biodiversidad y apoyo al desarrollo de actividades del mercado en la Región Andina (CAN) 2000-2009

OpenAIRE

Martín Hilarión, Jorge Luis

2012-01-01

Este trabajo de investigación analiza la importancia de la cooperación internacional para la gestión de biodiversidad entregada por el Global Environmental Facilty-GEF, para la conservación y uso sostenible de la biodiversidad en la cuenca Andino-amazónica. Esto a través del estudio de los proyectos de alcance regional financiados a dos instituciones subregionales, el primero, “Estrategia Regional para la Conservación y Uso Sostenible de Recursos en el Amazonas” perteneciente al Tratado de Co...

Riesgo en la zona andina tropical por laderas inestables

OpenAIRE

Duque Escobar, Gonzalo

2000-01-01

Las presentes notas relacionadas con la definición de riesgo y amenaza, y la aplicación de estos conceptos para eventos como los relacionados con la inestabilidad de las vertientes, pueden tener importancia para las comunidades de la región andina. Este trabajo se ocupa de una de las amenazas más importantes del medio tropical andino: los deslizamientos de tierra vistos desde la óptica de los desastres naturales. Se definen los movimientos de masas. Luego se discuten los parámetros de la ines...

La fuente Inca de Aypate

OpenAIRE

Astuhuamán Gonzáles, César W.; Ministerio de Cultura

2013-01-01

La mayor parte del cerro Aypate está cubierto por la tupida vegetación del húmedo bosque de neblina, la cual concentra y produce el elemento más valioso para los pueblos andinos: el agua. El asentamiento Inca de Aypate se construyó sobre el cerro que forma parte de una cadena montañosa de la que nacen pequeñas quebradas que alimentan las subcuencas de los ríos Quiroz y Macará, que a su vez integran la cuenca del Chira.

Las relaciones de comercio e inversión entre Colombia y Venezuela

OpenAIRE

Eglé Iturbe de Blanco

1997-01-01

Venezuela y Colombia cuentan con una larga trayectoria histórica en sus relaciones económicas. Comercian entre ellas y sus nacionales a lo largo de la frontera desde su nacimiento como naciones e interactúan entre ambos países como si fuera uno solo. Al norte, en la península de la Guajira, viven poblaciones indígenas comunes cuyo sustento es el comercio entre ambos lados de la frontera; y al sur, en los estados andinos venezolanos limítrofes con los llanos colombianos, tradicionalmente se ha...

Indios urbanos: inmigraciones, alteridad y ladinización en Santiago de Chile (siglos XVI-XVII

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Jaime Valenzuela Márquez

2014-05-01

Full Text Available During the period following the Conquista and when the Santiago de Chile's urban society was formed, one can observe various indigenous peoples that migrated to the city: Andinos, Huarpes of Cuyo, Juries from Tucaman, and Mapuche-Huilliches from the south of the Kingdom of Chile. The objective of this article is to show the great geographic and ethnic diversity of the city by studying the arrival, deployment and mobility of these actors and their descendants, as well as their forms of settlement and their strategies for integration.

Análisis de redes sociales para la gobernanza de un área protegida y su zona de amortiguación en el bosque templado del sur de Chile

OpenAIRE

Mardones, Gonzalo

2017-01-01

Para transitar desde el manejo hacia la gobernanza de las áreas protegidas y sus zonas aledañas, se requiere el involucramiento y la colaboración de las comunidades locales, además de múltiples otros actores involucrados en la conservación y el desarrollo de dicho territorio. El presente trabajo presenta un análisis de redes sociales de los actores con interés y/o influencia en la zona de amortiguación del Parque Nacional Alerce Andino (PNAA) y la Reserva Nacional Llanquihue (RNLL), ubicado e...

Música y fiesta en la construcción del territorio nasa (Colombia

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Carlos Miñana Blasco

2008-01-01

Full Text Available El pueblo nasa , en el sur occ idente andino de Colombia, reafirma y construye a diario sus territorios no sólo por medios legales, trabajando o luchando por la tierra, sino también con ritos, fiestas, música y bailes. Este artículo, basado en un trabajo de campo de varios años, señala vínculos significativos y continuidades entre los territorios de los cacicazgos precolombinos y las fronteras delimitadas y celebradas por las actuales prácticas rituales y musicales.

Nuevos productos alimenticios en el comercio mundial: situación y perspectivas actuales para el cultivo y exportación de quinua por parte del Ecuador

OpenAIRE

Valenzuela Chauca, Diana Pamela

2016-01-01

El presente trabajo de investigación plantea un estudio sobre la producción de quinua, enfocado en sus principales proveedores: Bolivia, Ecuador y Perú. El objetivo que guió esta investigación fue determinar las tendencias de la evolución de la producción y el comercio internacional de quinua en los países andinos, y en particular el Ecuador. Para ello se estudiaron las características, actores, tendencias del cultivo y comercio internacional de la quinua. En el capítulo uno, se presentan las...

Medicinas tradicionales andinas y su despenalización: entrevista con Walter Álvarez Quispe

OpenAIRE

Quispe, Walter Álvarez; Loza, Carmen Beatriz

2014-01-01

Walter Álvarez Quispe, terapeuta kallawaya y biomédico especializado en cirugía general y ginecología, presenta la lucha de los terapeutas tradicionales y alternativos por la depenalización de estos sistemas médicos andinos realizada entre 1960 y 1990. Bolivia se torna el primer país en América Latina y el Caribe en despenalizar la medicina tradicional antes de los planteamientos de la Conferencia Internacional sobre Atención Primaria de Salud (Alma-Ata, 1978). Los datos aportados por el entr...

Presentacio?n. Experiencias y propuestas de educacio?n intercultural bilingu?e en los cantones Cayambe y Pedro Moncayo (Ecuador)

OpenAIRE

Granda Mercha?n, Sebastia?n

2014-01-01

En el 2004, luego de 10 an?os de experiencia en los pa?ramos andinos de la Provincia de Cotopaxi, la Universidad Polite?cnica Salesiana oferta la Carrera de Educacio?n Intercultural Bilingu?e en la ciudad de Cayambe con el objetivo de atender las demandas de formacio?n de los docentes de las escuelas y colegios de la Jurisdiccio?n de Educacio?n Intercultural Bilingu?e de la zona. Para ese entonces, habi?an transcurrido ya 15 an?os desde que se institucionalizo? la Educacio?n Intercultural Bil...

El tarwi o chocho: una de las principales fuentes de proteína vegetal de las comunidades indígenas de los Andes Centrales

OpenAIRE

Planchuelo, Ana M.; Fuentes, Esteban P.

2005-01-01

El lupino andino (Lupinus mutabilis Sweet) conocido también como tarwi o chocho, es una especie de leguminosa nativa de los Andes Centrales. Su domesticación se remonta a los principios de la cultura Nazca y desde ese entonces hasta la actualidad el cultivo está ampliamente difundido en las laderas montañosas y en los altos valles de Ecuador, Perú y Bolivia. La importancia del lupino para las comunidades andinas prehispánicas quedo documentada en pinturas de cerámicas y en tributos encontrado...

Bogotá 450 años

OpenAIRE

Santana, Pedro; Vargas, Julián; Zambrano, Fabio; Díaz, Juan; Goueset, Vincent; Giraldo, Fabio; González, Hernando; López, Néstor; Andrade, Irma; Arbeláez, Juan Díaz; Bernal, Por Gustavo Samper; Cuervo, Luis Augusto; Fernández, Néstor López; Goueset, Vincent; Isaza, Fabio Giraldo

2015-01-01

El pasado 6 de agosto, Bogotá cumplió 450 años de fundada. Con este motivo durante los meses finales de 1987 un grupo de investigadores que trabajan sobre distintos aspectos de la problemática de la ciudad capital de Colombia, decidimos reunir-nos para discutir la posibilidad de un trabajo colectivo que tomara como objeto de su reflexión la ciudad de Bogotá. Esta idea fue promovida en el marco del Convenio Foro Nacional por Colombia-Instituto Francés de Estudios Andinos. De hecho las dos inst...

Propiedades nutricionales y antioxidantes de la cañihua (Chenopodium pallidicaule Aellen)

OpenAIRE

Bartolo Estrella, Dolly Elisa

2013-01-01

El objetivo de esta revisión fue detallar las propiedades nutricionales y antioxidantes de la cañihua (Chenopodium pallidicaule Aellen). La cañihua es uno de los granos andinos menos estudiados y más nutritivos, debido a su contenido y calidad proteica. Esta planta a causa de su crecimiento en condiciones climáticas extremas, como en el altiplano (4000 m.s.n.m.), probablemente ha desarrollado una protección natural contra la oxidación. Los reportes indican que la cañihua tiene una calidad pro...

Estrategias sustentables de manejo de los productores de la feria agroecológica de Córdoba

OpenAIRE

Cabanillas, Carmen; Tablada, Margot; Ferreyra, Luis Alberto; Ramos, Érica

2015-01-01

En la provincia de Córdoba, Argentina, se desarrolla la Feria Agroecológica que reúne a pequeños productores de hortalizas, aromáticas, cereales, oleaginosas, flores, frutales y andinos, en transición agroecológica. El objetivo de este trabajo fue caracterizar a los agroecosistemas en relación a las estrategias sustentables de manejo que implementan los productores de la Feria Agroecológica de Córdoba en la dimensión ambiental. Mediante una encuesta se evaluaron: la diversificación de la prod...

Desarrollo de producto sobre la base de harinas de cereales y leguminosa para niños celíacos entre 6 y 24 meses; I: Formulación y aceptabilidad

OpenAIRE

Cerezal Mezquita, P.; Urtuvia Gatica, V.; Ramírez Quintanilla, V.; Romero Palacios, N.; Arcos Zavala, R.

2011-01-01

La revalorización de los cultivos andinos, quinua (Chenopodium quinua Willd) y lupino (Lupinus albus L), para ser utilizados en mezclas alimenticias, con cereales tradicionales como maíz (Zea mays L.) y arroz (Oryza sativa L.), originan mezclas sin gluten que constituyen una buena alternativa para la alimentación de niños menores de 24 meses que sufren la enfermedad celíaca, ya que mejoran la calidad de la proteína, por compensación de los aminoácidos esenciales, e incide en la diversificació...

Co-evolução entre raças fisiológicas de colletotrichum lindemuthianum e feijoeiro Co-evolution of physiological races of colletotrichum lindemuthianum and common bean

Directory of Open Access Journals (Sweden)

Alisson Fernando Chiorato

2006-01-01

Full Text Available O agente causal da antracnose (Colletotrichum lindemuthianum em feijoeiro comum é classificado, assim como seu hospedeiro, em Andino e Mesoamericano, sendo a resposta à infecção dependente da origem genética de um e de outro. Desta forma, o objetivo do presente trabalho foi avaliar 220 acessos do Banco de Germoplasma de feijoeiro (Phaseolus vulgaris do Instituto Agronômico, IAC, quanto à infecção por três raças fisiológicas do patógeno (31, 65 e 89, caracterizando uma possível co-evolução entre a origem do acesso e do patógeno. No estudo, foram utilizados 120 acessos de origem mesoamericana, 57 andinos e 43 cultivares geneticamente melhoradas. Além dos dados relacionados à infecção, foram avaliados 23 descritores morfo-agronômicos com finalidade de melhor caracterizar os acessos em relação aos seus respectivos centros de origem. As análises estatísticas foram baseadas em componentes principais a fim de exibir graficamente a variabilidade em função da origem do patógeno e dos acessos. Dentre os acessos mesoamericanos, 50% foram suscetíveis às três raças, enquanto nos andinos apenas 33% foram suscetíveis. Entre as cultivares geneticamente melhoradas, 79% foram resistentes a pelo menos uma das raças, provavelmente devido a seleções para resistência ao C. lindemuthianum. Nos gráficos da análise de componentes principais, a maioria dos acessos resistentes foi agrupada na região de dispersão dos acessos andinos. Os resultados permitiram estabelecer uma associação entre a origem do feijoeiro e do patógeno da antracnose, ajudando assim no conhecimento biológico da reação dos acessos ao C. lindemuthianum e orientando a escolha de genitores para realização de cruzamentos visando à resistência a essa doença.The causal agent of anthracnose (Colletotrichum lindemuthianum of common bean and its host, are classified as Andean and Mesoamerican. Response to infection depends on the genetic origin of both plant

Collas e cambas do outro lado da fronteira: aspectos da distribuição diferenciada da imigração boliviana em Corumbá, Mato Grosso do Sul Collas y cambas del otro lado de la frontera: aspectos de la distribución diferenciada de la inmigración boliviana en Corumbá, Mato Grosso del Sur Collas and cambas from the other side of the border: factors of the unusual distribution of Bolivian immigration in Corumbá, State of Mato Grosso do Sul, Brazil

Directory of Open Access Journals (Sweden)

Sylvain Souchaud

2008-12-01

Full Text Available Este estudo busca apresentar os resultados da pesquisa de campo acerca dos bolivianos residentes na cidade de Corumbá-MS, destacando suas características. Procurou-se captar os diferenciais da imigração boliviana para a cidade de Corumbá, identificando aspectos culturais, territoriais e etno-lingüísticos das áreas de origem que se refletem nos diferenciais sociodemográficos existentes - entre um mesmo contingente imigrante - no lugar de destino: Corumbá/Brasil. Tais aspectos constituem fatores importantes para a leitura da própria configuração urbana da localização da imigração boliviana em Corumbá.Este estudio busca presentar los resultados de la investigación de campo acerca de los bolivianos residentes en la ciudad de Corumbá - MS, destacando sus características. Se procuró captar las diferencias de la inmigración boliviana a la ciudad de Corumbá, identificando aspectos culturales, territoriales y étnico-lingüísticos de las áreas de origen que se reflejan en las diferencias socio-demográficas existentes - entre un mismo contingente inmigrante - en el lugar de destino: Corumbá/Brasil. Tales aspectos constituyen factores importantes para la lectura de la propia configuración urbana de la localización de la inmigración boliviana en Corumbá.This study discusses the findings of field research on Bolivian residents living in the city of Corumbá, Mato Grosso do Sul, Brazil, with special emphasis on their characteristics. The research was aimed at detecting the unusual aspects of Bolivian immigration to the city of Corumbá, identifying cultural, territorial and ethno-linguistic aspects of the areas of origin, which are reflected in the sociodemographic differences that exist within the same contingent of immigrants in their place of destination: Corumbá, Brazil. These factors are important for a reading of the urban characterization of Bolivian immigration in Corumbá.

El regreso de Túpac Katari. Bolivia y los procesos de transformación global del capitalismo

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Iñigo Errejón Galván

2007-01-01

Full Text Available La victoria electoral en diciembre de 2005 del Movimiento al socialismo encabezado por Evo Morales tuvo una significación mundial. En este artículo defenderemos que los acontecimientos políticos bolivianos de los últimos tiempos deben ser interpretados como algo más que un mero recambio en las elites políticas del país. Lo que está ocurriendo en Bolivia es, a nuestro juicio, la cristalización institucional de un conjunto de procesos que convergieron en la apertura de un ciclo de luchas anti-neoliberales iniciado en el año 2000. Los orígenes y efectos de este «ciclo rebelde» trascienden la escala estatal aún cuando ésta represente su espacio de materialización más visible. Een primer lugar, usando la perspectiva del «sistema-mundo» de Wallerstein, llevaremos a cabo una explicación de las tendencias históricas de transformación en la distribución geopolítica del poder y en las dinámicas de integración del Capitalismo. Prestaremos particular atención a los efectos de reordenación sistémica de la globalización neoliberal desde los años 70. segundo lugar, examinaremos los efectos del Neoliberalismo en la situación geopolítica de Bolivia y su influencia determinante en la emergencia de las identidades políticas indígenas, así como en la crisis de protagonismo político del proletariado minero boliviano, en el marco de procesos de impugnación de la «colonialidad». Een tercer lugar, analizaremos algunos aspectos de la influencia de los elementos anteriores —dinámicas sistémicas globales y transformación de la estructura de clases— en el proceso constituyente actualmente abierto en Bolivia. Intentaremos describir las interacciones entre los actores políticos que intervienen en el proceso constituyente prestando especial atención al papel de los movimientos sociales

Representaciones del Mundo Andino en un relato oral sobre fantasmas.

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Florencia Raquel Angulo Villán

2010-11-01

Full Text Available Este trabajo centra el análisis en las narraciones de tradición oral que tematizan las historias de fantasmas. Si bien existen “constelaciones de imágenes” más o menos constantes compartidas por el ser humano y su entorno material y social, éstas se enriquecen en tanto pueden ser leídas desde los códigos de la cultura que las produce. En este caso, representada por la zona andina. La metodología utilizada pondrá en relación las categorías de imaginario desde una perspectiva antropológica y los aportes de la filosofía andina, sustentada en los principios de reciprocidad y complementariedad. La lectura analítica tiene como objetivo poner de manifiesto cómo los discursos orales que circulan en una comunidad en particular se constituyen como estrategias de consolidación de la “memoria” de un pueblo.

The MAS Six Years in Power in Bolivia

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Ton Salman

2012-04-01

Full Text Available Review Essay of:– The Rise of Evo Morales and the MAS, by Sven Harten. London/New York: Zed Books, 2011.– Evo Morales and the Movimiento al Socialismo in Bolivia; The First Term in Context, edited by Adrian J. Pearce. London, Institute for the Study of the Americas, 2011.– El estado de derecho como tiranía, by Luis Tapia. La Paz: CIDES/UMSA, 2011.– From Rebellion to Reform in Bolivia: Class Struggle, Indigenous Liberation and the Politics of Evo Morales, by Jeffery R. Webber. Chicago: Haymarket Books, 2011.– La democracia desde los márgenes: Transformaciones en el campo político boliviano, by María Teresa Zegada, with Claudia Arce, Gabriela Canedo and Alber Quispe. La Paz: Muela del Diablo Editores/CLACSO, 2011.

Resource selection and its implications for wide-ranging mammals of the brazilian cerrado.

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Vynne, Carly; Keim, Jonah L; Machado, Ricardo B; Marinho-Filho, Jader; Silveira, Leandro; Groom, Martha J; Wasser, Samuel K

2011-01-01

Conserving animals beyond protected areas is critical because even the largest reserves may be too small to maintain viable populations for many wide-ranging species. Identification of landscape features that will promote persistence of a diverse array of species is a high priority, particularly, for protected areas that reside in regions of otherwise extensive habitat loss. This is the case for Emas National Park, a small but important protected area located in the Brazilian Cerrado, the world's most biologically diverse savanna. Emas Park is a large-mammal global conservation priority area but is too small to protect wide-ranging mammals for the long-term and conserving these populations will depend on the landscape surrounding the park. We employed novel, noninvasive methods to determine the relative importance of resources found within the park, as well as identify landscape features that promote persistence of wide-ranging mammals outside reserve borders. We used scat detection dogs to survey for five large mammals of conservation concern: giant armadillo (Priodontes maximus), giant anteater (Myrmecophaga tridactyla), maned wolf (Chrysocyon brachyurus), jaguar (Panthera onca), and puma (Puma concolor). We estimated resource selection probability functions for each species from 1,572 scat locations and 434 giant armadillo burrow locations. Results indicate that giant armadillos and jaguars are highly selective of natural habitats, which makes both species sensitive to landscape change from agricultural development. Due to the high amount of such development outside of the Emas Park boundary, the park provides rare resource conditions that are particularly important for these two species. We also reveal that both woodland and forest vegetation remnants enable use of the agricultural landscape as a whole for maned wolves, pumas, and giant anteaters. We identify those features and their landscape compositions that should be prioritized for conservation, arguing

Resource selection and its implications for wide-ranging mammals of the brazilian cerrado.

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Carly Vynne

Full Text Available Conserving animals beyond protected areas is critical because even the largest reserves may be too small to maintain viable populations for many wide-ranging species. Identification of landscape features that will promote persistence of a diverse array of species is a high priority, particularly, for protected areas that reside in regions of otherwise extensive habitat loss. This is the case for Emas National Park, a small but important protected area located in the Brazilian Cerrado, the world's most biologically diverse savanna. Emas Park is a large-mammal global conservation priority area but is too small to protect wide-ranging mammals for the long-term and conserving these populations will depend on the landscape surrounding the park. We employed novel, noninvasive methods to determine the relative importance of resources found within the park, as well as identify landscape features that promote persistence of wide-ranging mammals outside reserve borders. We used scat detection dogs to survey for five large mammals of conservation concern: giant armadillo (Priodontes maximus, giant anteater (Myrmecophaga tridactyla, maned wolf (Chrysocyon brachyurus, jaguar (Panthera onca, and puma (Puma concolor. We estimated resource selection probability functions for each species from 1,572 scat locations and 434 giant armadillo burrow locations. Results indicate that giant armadillos and jaguars are highly selective of natural habitats, which makes both species sensitive to landscape change from agricultural development. Due to the high amount of such development outside of the Emas Park boundary, the park provides rare resource conditions that are particularly important for these two species. We also reveal that both woodland and forest vegetation remnants enable use of the agricultural landscape as a whole for maned wolves, pumas, and giant anteaters. We identify those features and their landscape compositions that should be prioritized for

Mammalian carnivore occupancy is inversely related to presence of domestic dogs in the high Andes of Ecuador.

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Galo Zapata-Ríos

Full Text Available Although the Andes have long been occupied by people, habitat loss, fragmentation through deforestation, and other human activities such as introduction of invasive species have increased drastically during the past century. The Ecuadorian Andes are considered a biodiversity hotspot. However, the fauna and threats to the region are poorly studied, and understanding of factors that shape the distribution of species in habitats disturbed by human activities is needed to identify and mitigate region-wide threats to wildlife. We evaluated factors associated with patterns of occurrence of Andean carnivores in landscapes of the northern Ecuadorian Andes, particularly habitat loss, fragmentation, and occupancy of domestic dogs, and determined whether thresholds occurred for these factors beyond which carnivore occurrence declined markedly. Five study areas (each 20 x 20 km were surveyed with a total effort of 2,800 camera trap nights. Occupancies of four of the eight carnivores known from the region were best predicted by occupancy of domestic dogs rather than measures of habitat loss and fragmentation [Andean fox (Pseudalopex culpaeus, puma (Puma concolor, striped hog-nosed skunk (Conepatus semistriatus, and Andean bear (Tremarctos ornatus]. The two largest carnivores, puma and Andean bear, demonstrated significant threshold responses to the presence of domestic dogs at two sites. Four smaller carnivores were recorded too infrequently to model occupancy, and at least two of these species appear to be in decline. The magnitude of domestic dog impacts on native species in tropical areas like the Ecuadorian Andes currently are not recognized. Results of our study indicate that small and large carnivores are in urgent need of conservation and clearly point to dogs as a significant threat to a broad range of native species.

Sulforaphane-induced apoptosis in Xuanwei lung adenocarcinoma cell line XWLC-05.

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Zhou, Lan; Yao, Qian; Li, Yan; Huang, Yun-Chao; Jiang, Hua; Wang, Chuan-Qiong; Fan, Lei

2017-01-01

Xuanwei district in Yunnan Province has the highest incidence of lung cancer in China, especially among non-smoking women. Cruciferous vegetables can reduce lung cancer risk by prompting a protective mechanism against respiratory tract inflammation caused by air pollution, and are rich in sulforaphane, which can induce changes in gene expression. We investigated the effect of sulforaphane-induced apoptosis in Xuanwei lung adenocarcinoma cell line (XWCL-05) to explore the value of sulforaphane in lung cancer prevention and treatment. Cell growth inhibition was determined by methyl thiazolyl tetrazolium assay; cell morphology and apoptosis were observed under transmission electron microscope; cell cycle and apoptosis rates were detected using flow cytometry; B-cell lymphoma 2 (Bcl-2) and Bcl-2-like protein 4 (Bax) messenger RNA expression were determined by quantitative PCR; and p53, p73, p53 upregulated modulator of apoptosis (PUMA), Bax, Bcl-2, and caspase-9 protein expression were detected by Western blotting. Sulforaphane inhibited XWLC-05 cell growth with inhibitory concentration (IC) 50 of 4.04, 3.38, and 3.02 μg/mL at 24, 48, and 72 hours, respectively. Sulforaphane affected the XWLC-05 cell cycle as cells accumulated in the G2/M phase. The proportion of apoptotic cells observed was 27.6%. Compared with the control, the sulforaphane group showed decreased Bcl-2 and p53 expression, and significantly increased p73, PUMA, Bax, and caspase-9 protein expression (P cell apoptosis. Its possible mechanism may involve the upregulation of p73 expression and its effector target genes PUMA and Bax in lung cancer cells, downregulation of the anti-apoptotic gene B cl -2, and activation of caspase-9. It may also involve downregulation of the mutant p53 protein. © 2016 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd.

PUMA: a puzzle piece in chloroquine's antimelanoma activity.

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Amaravadi, Ravi K

2013-09-01

Chloroquine (CQ) can induce cell death in a subset of cancer cell lines, and some melanoma cell lines are quite susceptible. Although it is well known that CQ impairs lysosomal function and can serve as an autophagy inhibitor, the molecular target of CQ and the subsequent cascade of events that lead to cell death are not fully understood. Recent evidence indicates that in melanoma cell lines, CQ induces apoptosis by preventing degradation of the pro-apoptotic BH3-only protein p53-upregulated modulator of apoptosis. This finding adds to the unfolding story of CQ's mechanism of action as a cancer therapeutic agent.

Loss of a Single Mcl-1 Allele Inhibits MYC-Driven Lymphomagenesis by Sensitizing Pro-B Cells to Apoptosis

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Stephanie Grabow

2016-03-01

Full Text Available MCL-1 is critical for progenitor cell survival during emergency hematopoiesis, but its role in sustaining cells undergoing transformation and in lymphomagenesis is only poorly understood. We investigated the importance of MCL-1 in the survival of B lymphoid progenitors undergoing MYC-driven transformation and its functional interactions with pro-apoptotic BIM and PUMA and the tumor suppressor p53 in lymphoma development. Loss of one Mcl-1 allele almost abrogated MYC-driven-lymphoma development owing to a reduction in lymphoma initiating pre-B cells. Although loss of the p53 target PUMA had minor impact, loss of one p53 allele substantially accelerated lymphoma development when MCL-1 was limiting, most likely because p53 loss also causes defects in non-apoptotic tumor suppressive processes. Remarkably, loss of BIM restored the survival of lymphoma initiating cells and rate of tumor development. Thus, MCL-1 has a major role in lymphoma initiating pro-B cells to oppose BIM, which is upregulated in response to oncogenic stress.

Carnivore fecal chemicals suppress feeding by Alpine goats (Capra hircus).

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Weldon, P J; Graham, D P; Mears, L P

1993-12-01

The efficacy of carnivore and ungulate fecal chemicals in suppressing the feeding behavior of Alpine goats (Capra hircus) was examined. In the first four experiments, goats were offered food covered with paper strips treated with fecal extracts of the Bengal tiger, Siberian tiger, African lion, and brown bear, respectively; food covered with solvent-treated and untreated (plain) papers served as controls in each experiment. Goats made fewer head entries into, and ate less food from, buckets containing fecal extracts. In the fifth experiment, goats were offered food covered with paper strips treated with fecal extracts of the puma, Dorcas gazelle, white-bearded gnu, and conspecifics; food covered with solvent-treated and plain papers again served as controls. The amounts of food consumed from buckets containing puma, gazelle, gnu, and solvent treatments were statistically indistinguishable, but less food was consumed from them than from buckets containing the goat-scented or plain papers. No significant differences among treatments were detected with respect to head entries. Field experiments are needed on the use of predator-derived chemicals to reduce damage by goats to vegetation.

BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues.

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Muthalagu, Nathiya; Junttila, Melissa R; Wiese, Katrin E; Wolf, Elmar; Morton, Jennifer; Bauer, Barbara; Evan, Gerard I; Eilers, Martin; Murphy, Daniel J

2014-09-11

MYC is one of the most frequently overexpressed oncogenes in human cancer, and even modestly deregulated MYC can initiate ectopic proliferation in many postmitotic cell types in vivo. Sensitization of cells to apoptosis limits MYC's oncogenic potential. However, the mechanism through which MYC induces apoptosis is controversial. Some studies implicate p19ARF-mediated stabilization of p53, followed by induction of proapoptotic BH3 proteins NOXA and PUMA, whereas others argue for direct regulation of BH3 proteins, especially BIM. Here, we use a single experimental system to systematically evaluate the roles of p19ARF and BIM during MYC-induced apoptosis, in vitro, in vivo, and in combination with a widely used chemotherapeutic, doxorubicin. We find a common specific requirement for BIM during MYC-induced apoptosis in multiple settings, which does not extend to the p53-responsive BH3 family member PUMA, and find no evidence of a role for p19ARF during MYC-induced apoptosis in the tissues examined. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

Campesinos, pueblos originarios y sectores obrero-populares en el proceso de cambio boliviano

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Magdalena Cajías De La Vega

2012-08-01

Full Text Available O artigo analisa as transformações ocorridas na Bolívia durante a última década, ponderando a importância dos diferentes setores sociais mobilizados contra as medidas neoliberais, destacando o papel dos povos originários e dos campesinos indígenas organizados sindicalmente, que emergem politicamente neste período. Busca retratar o processo de construção de um poder alternativo baseado na organização indígena, na força adquirida pelos cocaleiros e na “Confederación Sindical Única de Trabajadores Campesinos de Bolivia”, que contribuíram para o triunfo eleitoral do “Movimiento al Socialismo” que elege o presidente Evo Morales. Por fim, destaca a importância da “Central Obrera Boliviana”, especialmente do movimento mineiro organizado por meio da “Federación Sindical de Trabajadores Mineros de Bolivia” que promoveu a "Guerra del Gas", em outubro de 2003, e que acabou subestimado pelas visões políticas dominantes dentro do Movimiento al Socialismo.

Assessing temporal genetic variation in a cougar population: Influence of harvest and neighboring populations

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Rebeca L. Juarez; Michael K. Schwartz; Kristine L. Pilgrim; Daniel J. Thompson; Stephanie A. Tucker; Joshua B. Smith; Jonathan A. Jenks

2016-01-01

The geography of the Black Hills region of South Dakota and Wyoming may limit connectivity for many species. For species with large energetic demands and large home ranges or species at low densities this can create viability concerns. Carnivores in this region, such as cougars (Puma concolor), have the additive effect of natural and human-induced mortality;...

Seroepidemiology of Toxoplasma gondii in zoo animals in selected zoos in the midwestern United States.

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de Camps, Silvia; Dubey, J P; Saville, W J A

2008-06-01

Toxoplasma gondii infections in zoo animals are of interest because many captive animals die of clinical toxoplasmosis and because of the potential risk of exposure of children and elderly to T. gondii oocysts excreted by cats in the zoos. Seroprevalence of T. gondii antibodies in wild zoo felids, highly susceptible zoo species, and feral cats from 8 zoos of the midwestern United States was determined by using the modified agglutination test (MAT). A titer of 1:25 was considered indicative of T. gondii exposure. Among wild felids, antibodies to T. gondii were found in 6 (27.3%) of 22 cheetahs (Acynonyx jubatus jubatus), 2 of 4 African lynx (Caracal caracal), 1 of 7 clouded leopards (Neofelis nebulosa), 1 of 5 Pallas cats (Otocolobus manul), 12 (54.5%) of 22 African lions (Panthera leo), 1 of 1 jaguar (Panthera onca), 1 of 1 Amur leopard (Panthera pardus orientalis), 1 of 1 Persian leopard (Panthera pardus saxicolor), 5 (27.8%) of 18 Amur tigers (Panthera tigris altaica), 1 of 4 fishing cats (Prionailurus viverrinus), 3 of 6 pumas (Puma concolor), 2 of 2 Texas pumas (Puma concolor stanleyana), and 5 (35.7%) of 14 snow leopards (Uncia uncia). Antibodies were found in 10 of 34 feral domestic cats (Felis domesticus) trapped in 3 zoos. Toxoplasma gondii oocysts were not found in any of the 78 fecal samples from wild and domestic cats. Among the macropods, antibodies were detected in 1 of 3 Dama wallabies (Macropus eugenii), 1 of 1 western grey kangaroo (Macropus fuliginosus), 1 of 2 wallaroos (Macropus robustus), 6 of 8 Bennett's wallabies (Macropus rufogriseus), 21 (61.8%) of 34 red kangaroos (Macropus rufus), and 1 of 1 dusky pademelon (Thylogale brunii). Among prosimians, antibodies were detected in 1 of 3 blue-eyed black lemurs (Eulemur macaco flavifrons), 1 of 21 ring-tailed lemurs (Lemur catta), 2 of 9 red-ruffed lemurs (Varecia variegata rubra), and 2 of 4 black- and white-ruffed lemurs (Varecia variegata variegata). Among the avian species tested, 2 of 3 bald

Feline Immunodeficiency Virus Cross-Species Transmission: Implications for Emergence of New Lentiviral Infections.

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Lee, Justin; Malmberg, Jennifer L; Wood, Britta A; Hladky, Sahaja; Troyer, Ryan; Roelke, Melody; Cunningham, Mark; McBride, Roy; Vickers, Winston; Boyce, Walter; Boydston, Erin; Serieys, Laurel; Riley, Seth; Crooks, Kevin; VandeWoude, Sue

2017-03-01

Owing to a complex history of host-parasite coevolution, lentiviruses exhibit a high degree of species specificity. Given the well-documented viral archeology of human immunodeficiency virus (HIV) emergence following human exposures to simian immunodeficiency virus (SIV), an understanding of processes that promote successful cross-species lentiviral transmissions is highly relevant. We previously reported natural cross-species transmission of a subtype of feline immunodeficiency virus, puma lentivirus A (PLVA), between bobcats ( Lynx rufus ) and mountain lions ( Puma concolor ) for a small number of animals in California and Florida. In this study, we investigate host-specific selection pressures, within-host viral fitness, and inter- versus intraspecies transmission patterns among a larger collection of PLV isolates from free-ranging bobcats and mountain lions. Analyses of proviral and viral RNA levels demonstrate that PLVA fitness is severely restricted in mountain lions compared to that in bobcats. We document evidence of diversifying selection in three of six PLVA genomes from mountain lions, but we did not detect selection among 20 PLVA isolates from bobcats. These findings support the hypothesis that PLVA is a bobcat-adapted virus which is less fit in mountain lions and under intense selection pressure in the novel host. Ancestral reconstruction of transmission events reveals that intraspecific PLVA transmission has occurred among panthers ( Puma concolor coryi ) in Florida following the initial cross-species infection from bobcats. In contrast, interspecific transmission from bobcats to mountain lions predominates in California. These findings document outcomes of cross-species lentiviral transmission events among felids that compare to the emergence of HIV from nonhuman primates. IMPORTANCE Cross-species transmission episodes can be singular, dead-end events or can result in viral replication and spread in the new species. The factors that determine which

Primer registro de infestación en un reptil por larvas de Amblyomma parvitarsum (Acari: Ixodidae en Argentina

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Gabriel Natalio Castillo

2015-05-01

Full Text Available Amblyomma parvitarsum es una garrapata endémica del Altiplano Andino de Argentina, Bolivia, Chile y Perú. En la provincia de San Juan adultos de esta garrapata fueron encontrados en el Parque Nacional San Guillermo sobre Vicugna vicugna. En Argentina también existen citas de adultos de A. parvitarsum sobre bovinos, ovinos y el ñandú . El primer caso de parasitismo de larvas de A. parvitarsum en Liolaemus fue realizado en Chile. El presente trabajo menciona por primera vez para Argentina la presencia de larvas de A. parvitarsum parasitando al lagarto Liolaemus eleodori.

¿Por qué el satélite Cóndor?

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Leonardo Ferrerira

2015-01-01

Full Text Available Estados Unidos y Rusia representan el 15 por ciento de la población mundial sin embargo utilizan el 50 por ciento de la órbita geoestacionaria, mientras todo el Tercer Mundo emplea menos del 10 por ciento. Los países del Pacto Andino se encuentran trabajando conjuntamente en el uso compartido de un solo sistemas satelital CONDOR. Pero los críticos norteamericanos consideran que es una manera ineficiente e irracional congestionar el espectro orbital. El artículo se centra en describir este proyecto y la lógica Andina, la soberanía

Potencial del tarwi (Lupinus mutabilis Sweet) como futura fuente proteínica y avances de su desarrollo agroindustrial

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Suca, G. R.; suca, C. A.

2016-01-01

El principal fortaleza de las leguminosas es la de sostener la producción global de proteínas, mitigando la falta de fuentes de proteínas de origen animal. Entre las legumbres, el tarwi (Lupinus mutabilis Sweet) es una de las fuentes más importantes de proteínas, especialmente en los países andinos. Además, las plantas de tarwi permiten la fijación de nitrógeno atmosférico y puede ser usado como cultivo rotativo en una agricultura ambientalmente sostenible. Sus semillas contienen más proteína...

Tratamiento comunitario al capital extranjero en los países de la Comunidad Andina desde 1970 hasta 1998

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Montes, Carmen Victoria

2001-01-01

Con la presente investigación, se pretende ir más allá de una simple descripción de las normas que han regulado el capital extranjero en los países de la Comunidad Andina. El propósito principal es hallar las razones, que han motivado el cambio en las normas y las incidencias que ha tenido ese cambio sobre la afluencia de capital. Asimismo se pretende ver si la legislación comunitaria de los países andinos es compatible con la de la OMC. Para cumplir con este propósito se ha...

Estudio de la influencia comercial sobre los barrios el Nogal, el Espartillal y el Retiro y su efecto en el precio del suelo, en el periodo 1993 – 2010.

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Cárdenas Carvajal, María Claudia

2014-01-01

El interés de esta monografía es describir el proceso de transformación urbana de los barrios El Retiro, El Espartillal y el Nogal de la ciudad de Bogotá, a partir del año 1993, en el cual se inauguró el Centro Comercial Andino. Se analiza y explica el desarrollo impulsado por el centro comercial sobre el territorio, transformando el uso de residencial e institucional a comercial y de servicios lo cual influyó directamente la densificación y valorización de los barrios. Por último se describe...

Estructura, diversidad y dinámica de la vegetación en el ecotono bosque-páramo: revisión de la evidencia en la Cordillera de Mérida

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Luis Daniel Llambí

2015-01-01

En los Andes tropicales, el límite altitudinal de los bosques corresponde a una compleja zona de transición entre el bosque paramero y el páramo andino. En el límite inferior de esta zona ocurre a su vez una transición gradual entre el bosque y las selvas nubladas. La ordenación del territorio en estos ecosistemas se ha convertido en un tema prioritario en virtud de la creciente amenaza que representan para su conservación las actividades agropecuarias y la minería. En este trabajo se revisar...

Vegetation Structure, Diversity and Dynamics in the Forest-Paramo Ecotone: A Review of the Evidence in the Cordillera de Mérida

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LLAMBÍ, Luis Daniel

2015-01-01

Acta Biológica Colombiana, 20(3):5-19, septiembre-diciembre de 2015. http://www.revistas.unal.edu.co/index.php/actabiol/index En los Andes tropicales, el límite altitudinal de los bosques corresponde a una compleja zona de transición entre el bosque paramero y el páramo andino. En el límite inferior de esta zona ocurre a su vez una transición gradual entre el bosque y las selvas nubladas. La ordenación del territorio en estos ecosistemas se ha convertido en un tema prioritario en virtud d...

Seminario Regional «La Cuestión Urbana en América Latina: Panorama y Desafíos de la investigación y la formación»

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Robert, Jérémy

2016-01-01

Quito está a punto de recibir la Tercera Conferencia de las Naciones Unidas sobre Desarrollo Sostenible y Vivienda, Hábitat III, en el mes de octubre de 2016, y pone el tema urbano en la agenda regional. En este marco, el IRD (Institut de Recherche Pour le Développement) con el apoyo del Instituto de la Ciudad de Quito, la Universidad Andina Simón Bolívar y del IFEA (Instituto Francés de Estudios Andinos UMIFRE 17, MAEDI/CNRS, USR 3337 América Latina), organizó el Seminario Regional «La Cuest...

Sistema electoral y representación política en el Perú actual

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Domingo García Belaunde

1987-12-01

Full Text Available El presente texto es la ponencia presentada al simposio internadonal "Sistema electoral y representación política-países andinos", organizado por el Instituto de Cooperación Iberoamericana y la Fundación Ebert, en colaboración con el Centro de Estudios Constitucionales y la Cátedra de Teoría del Estado de la UNED, y que se llevó a cabo en Segovia. del 25 al 27 de noviembre de 1986. Por razones de tiempo, no se pudo considerar comentario alguno acerca de las elecciones municipales realizadas en noviembre de 1986.

Políticas públicas y el derecho humano a la libertad sindical. El caso de los trabajadores agroindustriales del valle de Ica en Perú

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Orellana Pérez, Pedro Mijaíl

2016-01-01

Nuestra Latinoamérica ha estado casi constantemente a la saga de los procesos globales, particularmente los países andinos han tenido que enfrentar fenómenos que han venido en vulnerar su soberanía así como a los sectores más vulnerables de nuestras sociedades, tanto en el ejercicio y realización de sus derechos como en oportunidades para su desarrollo; en el caso peruano la crisis hiperinflacionaria de los ochentas, con recesión económica y financiera total, además del narcotráfico y el terr...

Plan estratégico para la quinua del Perú

OpenAIRE

Sheen Cortavarría, Erika María; Arbieto Ramírez, Erico; Pozo Molina, María Del Rocío del

2007-01-01

La quinua es un producto oriundo de la región andina que ha sido reconocida en el mundo por su alto nivel proteico. Su cultivo, ha experimentado a lo largo de toda la historia peruana una serie de cambios genéticos que les han dado a los países andinos la exclusividad de su crecimiento a pesar que se han hecho esfuerzos para propiciar su adaptación a otros países. El Perú es el principal productor de quinua y el segundo país que exporta este cultivo, principalmente, al mercado norteamerica...

MODELACIÓN DEL EFECTO DE LA PODA Y RALEO SOBRE LAS DEFORMACIONES RESIDUALES LONGITUDINALES EN Eucalyptus globulus Labill.

OpenAIRE

Eduardo Navarrete; Carolina Valenzuela; Leif Nutto

2016-01-01

RESUMEN Se estudió una plantación de Eucalyptus globulus ubicada en el sector precordillerano andino de la región del Bío Bío, Chile, c on el objetivo de evaluar y modelar el efecto de la poda y raleo sobre las deformaciones residuales longitudinales (DRL) . El lugar de estudio correspondió a un rodal de 12 años de edad, el cual fue intervenido a los 2 años y medio de establecido, donde se evaluaron distintas intensidades de poda (0% y 60% de la altura total) y densidades de raleo (1.6...

MODELACIÓN DEL EFECTO DE LA PODA Y RALEO SOBRE LAS DEFORMACIONES RESIDUALES LONGITUDINALES EN Eucalyptus globulus Labill.

OpenAIRE

Navarrete, Eduardo; Valenzuela, Carolina; Nutto, Leif

2016-01-01

RESUMEN Se estudió una plantación de Eucalyptus globulus ubicada en el sector precordillerano andino de la región del Bío Bío, Chile, con el objetivo de evaluar y modelar el efecto de la poda y raleo sobre las deformaciones residuales longitudinales (DRL). El lugar de estudio correspondió a un rodal de 12 años de edad, el cual fue intervenido a los 2 años y medio de establecido, donde se evaluaron distintas intensidades de poda (0% y 60% de la altura total) y densidades de raleo (1.600 árb·ha...

IFEA 60 años

OpenAIRE

2014-01-01

15-09-2008 Riqueza paleontológica del Perú y Bolivia Museo Nacional de Historia Natural - Av. Arenales 1256, Jesús María Coord. Christian De Muizon (Ex Director del Instituto Francés de Estudios Andinos, Director de Investigación del CNRS, Museo Nacional de Historia Natural – Francia) Presentación de la Sesión Georges Lomné (Director del IFEA) Gerardo Lamas (Director del Museo de Historia Natural – UNMSM) La riqueza paleontológica del Perú: fauna de vertebrados marinos fósiles de la costa per...

Jóvenes, política y youtube : AZTRA estudio de caso

OpenAIRE

Nacimba Chicaiza, Henry Heriberto

2011-01-01

El grupo de folk metal andino AZTRA, tema de análisis, nace en Quito 18 de octubre 2001. El nombre se lo debe a la matanza acaecida en el ingenio azucarero del mismo nombre el 18 de octubre de 1977. Uno de los hallazgos de esta investigación da cuenta de cómo la banda se instituye como un agente de mediación entre su discurso y los jóvenes rockeros seguidores del grupo. Se instituye en la medida de complementar la experiencia del saber popular de la lucha y resistencia con la sistematización ...

Corredor Bimodal Cafetero

OpenAIRE

Duque Escobar, Gonzalo

2015-01-01

El Corredor Bimodal Cafetero es un proyecto de infraestructura estratégica que articula la Hidrovía del Magdalena con el Corredor Férreo del río Cauca, inscrito en el Plan Nacional de Desarrollo 2014/2018 y financiable con la salida de 30 mil toneladas diarias de carbón andino a la cuenca del Pacífico. Incluye el Túnel Cumanday para cruzar la Cordillera Central, el Ferrocarril Cafetero de 150 km y 3% de pendiente entre La Dorada y el Km 41, y la Transversal Cafetera de 108 km para una vía de...

Observaciones sobre la ecología del páramo andino de Monserrate Observaciones sobre la ecología del páramo andino de Monserrate

Directory of Open Access Journals (Sweden)

Sturm Helmut

1981-09-01

Full Text Available In a paramo region near Bogotá (Colombia, 3.230 m aboveseal evel investigations were made of clima, soil vegetation and fauna.  The mean temperature was 8.4 degrees C and the annual rainfall 1.221.4 mm. Sometimes great variations of relative humidity and of temperature near the soil surface could be registered. The properties of the black coloured paramosoil, wich probably is not a uniform type, are discussed. Its micromorphology and fauna were examined for the first time. The fauna is well developed and takes part intensivily in mixing the mineral and organic components. The soil type is classified as being between those which KUBIENA (1953 called "Pechtorf" and "Moderranker", The vegetation has been characterized by the estimation of the "Artmächtigkeit" (BRAUN-BLANQUET,1964 of the single species. The distribution and net production of Espeletia grandiflora Humb. & Bonpl., the most specificplant species in this paramo is discussed. The quantitative sampling of the fauna, especially of the arthropod fauna,was carried out by means of a combination of different methods to evaluate the density per litre and the density of activity. The mantle consisting of dead leaves of E. grandiflora proved to be a rich and characteristic "biotope". The facts are discussed partly by comparing them with correspondingfacts from a tropical rain forest.In a paramo region near Bogotá (Colombia, 3.230 m above seal evel investigations were made of clima, soil vegetation and fauna.  The mean temperature was 8.4 degrees C and the annual rainfall 1.221.4 mm. Sometimes great variations of relative humidity and of temperature near the soil surface could be registered. The properties of the black coloured paramo soil, wich probably is not a uniform type, are discussed. Its micromorphology and fauna were examined for the first time. The fauna is well developed and takes part intensivily in mixing the mineral and organic components. The soil type is classified as being between those which KUBIENA (1953 called "Pechtorf" and "Moderranker", The vegetation has been characterized by the estimation of the "Artmächtigkeit" (BRAUN-BLANQUET,1964 of the single species. The distribution and net production of Espeletia grandiflora Humb. & Bonpl., the most specific plant species in this paramo is discussed. The quantitative sampling of the fauna, especially of the arthropod fauna, was carried out by means of a combination of different methods to evaluate the density per litre and the density of activity. The mantle consisting of dead leaves of E. grandiflora proved to be a rich and characteristic "biotope". The facts are discussed partly by comparing them with corresponding facts from a tropical rain forest.

Use of robotics in a Radwaste treatment plant

International Nuclear Information System (INIS)

Leeks, C.W.E.

1991-01-01

A 762 Unimate Puma, clean room standard Robot has been installed and commissioned in the Radwaste Treatment Plant at the Winfrith Technology Centre. The robot interacts with a variety of purpose designed tools and proprietary welding equipment. It performs 13 dedicated tasks in the final closure and health physics operations, before the 500 litre waste drum is despatched from the plant. (author)

Control of Randomly Sampled Robotic Systems

Science.gov (United States)

1989-05-01

task is so cumbersome and complicated that we would not be able to do without lots of mistakes. To avoid this formidable business , a Lisp program is...Artificial Inteligence Laboratory, 1972. PumA26O.c Ned Mar 8 17:51:04 1989 1 #include <rnath.h> #define real float #define mm 6 #define G 9.83. #define M6

Abundance and food habits of cougars and bobcats in the Sierra San Luis, Sonora, Mexico

Science.gov (United States)

Hugo Luna Soria; Carlos A. Lopez Gonzalez

2005-01-01

Cougars (Puma concolor) and bobcats (Lynx rufus) are present throughout the Sky Islands of the Sonoran desert. We determined the abundance and food habits in northeastern Sonora, Mexico. Abundance indicated that cougars were common (4.19±5.57 cougars/100 km2 and 0.05±0.05 scats/km). According to the scat index, bobcats were more...

General Use of UAS in EW Environment-EW Concepts and Tactics for Single or Multiple UAS Over the Net-Centric Battlefield

Science.gov (United States)

2009-09-01

By Tiger and Flight Plan ..........................................193 Figure 124. Patriot to Be Destroyed By Puma and Flight Plan...systems, and its effectiveness depends on its ability to lock onto the heat source of low-flying fixed- and rotary-wing aircraft targets [33...different types of engines for different types of UAS: turbofans, two stroke , piston, rotary, turboprop, push and pull, electric. The lighter, smaller

Spatial Causality. An application to the Deforestation Process in Bolivia

Directory of Open Access Journals (Sweden)

Javier Aliaga

2011-01-01

Full Text Available Este trabajo analiza las causas de la deforestación para un conjunto representativo de municipios bolivianos. La literatura sobre economía ambiental insiste en la importancia de los factores físicos y sociales. Nos centramos en el último grupo de variables. Nuestro objetivo es identificar los mecanismos causales entre estos factores de riesgo y el problema de la deforestación. Con este fin, se presenta una estrategia de análisis para identificar mecanismos de causalidad espacial, basada en una secuencia de los multiplicadores de Lagrange. Los resultados que obtenemos para el caso de Bolivia confirman sólo parcialmente la visión tradicional del problema de la deforestación. De hecho, sólo encontramos signos inequívocos de causalidad en relación con la estructura de los derechos de propiedad.

RELIGIOSIDAD POPULAR: EL CASO DE LA VIRGEN DE URKUPIÑA EN SAN CARLOS DE BARILOCHE.

Directory of Open Access Journals (Sweden)

Ana Inés Barelli

2011-06-01

Full Text Available En los últimos años, la migración limítrofe en la Argentina no sólo se profundiza sino que inicia un proceso de visibilización social, dónde los aportes culturales y religiosos son percibidos y compartidos por toda la sociedad. La afluencia de estos grupos migratorios, en la Patagonia, dio lugar a un aporte cultural y religioso particular. El presente trabajo tiene como objetivo, poner en discusión el concepto de “religiosidad popular”, a la luz del caso de la devoción a la Virgen de Urkupiña de la comunidad boliviana en San Carlos de Bariloche. Analizaremos cómo las actividades religiosas y festivas de los migrantes bolivianos irrumpen en el espacio público generando nuevas adaptaciones devocionales, creando estrategias identitarias, y formulando nuevas territorialidades.

Evaluación de la eficiencia fotosintética del fitoplancton en un lago amazónico (Lago Boa y en un lago andino (Lago Guatavita Evaluation of the phytoplanktonic photosynthetic efficiency in an Amazon Lake (Lake Boa and in an Andean Lake (Lake Guatavita

Directory of Open Access Journals (Sweden)

Gabriel A. Pinilla

2006-01-01

Full Text Available La relación entre la fluorescencia variable y la fluorescencia máxima (Fv/Fm de las comunidades de algas se ha utilizado comúnmente como una medida de la eficiencia fotosintética del fitoplancton. Dicha eficiencia puede estar afectada por la localización de los ambientes acuáticos en distintas provincias limnológicas. En este trabajo se quiso establecer la diferencia en la relación Fv/Fm entre el lago Boa (150 msnm, Amazonía colombiana y el lago Guatavita (3000 msnm, cordillera oriental de los Andes colombianos. Los promedios de las eficiencias medidas fueron en general bajos (0,212 a 0,367 y 0,089 a 0,32 en los lagos Boa y Guatavita, respectivamente, lo que señala estrés fisiológico para las algas. La eficiencia fue mayor en aguas intermedias y presentó cambios fuertes entre épocas de muestreo y entre ecosistemas. En aguas superficiales se presentó fotoinhibición, la cual fue más fuerte en Guatavita. La eficiencia fotosintética fue menor en el lago andino debido posiblemente a diferencias climáticas, de altura sobre el nivel del mar y de estratificación. Durante los ensayos de laboratorio se observó que la eficiencia disminuyó con el tiempo, lo cual pudo deberse a una aclimatación de las algas a la oscuridad. Los datos de laboratorio confirmaron que el fitoplancton epilimnético del lago Guatavita estuvo fotoinhibido en la época de estratificación.Commonly relation between variable fluorescence and maximum fluorescence (Fv/Fm of the algae community has been utilized like a measure of the phytoplanktonic photosynthetic efficiency. Such efficiency can be affected by the water bodies' location in different limnological provinces. The goal of this work was to establish the differences in the Fv/Fm rate between Lake Boa (150 masl Colombian Amazon and Lake Guatavita (3000 masl, East Range in the Colombian Andes. In general, averages of the photosynthetic efficiencies were low (0.212 to 0.367 and 0.089 to 0.32 in lakes Boa and

Validation of Neutron Calculation Codes and Models by means of benchmark cases in the frame of the Binational Commission of Nuclear Energy. Criticality Experiments

International Nuclear Information System (INIS)

Dos Santos, Adimir; Siqueira, Paulo de Tarso D.; Andrade e Silva, Graciete Simões; Grant, Carlos; Tarazaga, Ariel E.; Barberis, Claudia

2013-01-01

In year 2008 the Atomic Energy National Commission (CNEA) of Argentina, and the Brazilian Institute of Energetic and Nuclear Research (IPEN), under the frame of Nuclear Energy Argentine Brazilian Agreement (COBEN), among many others, included the project “Validation and Verification of Calculation Methods used for Research and Experimental Reactors . At this time, it was established that the validation was to be performed with models implemented in the deterministic codes HUEMUL and PUMA (cell and reactor codes) developed by CNEA and those ones implemented in MCNP by CNEA and IPEN. The necessary data for these validations would correspond to theoretical-experimental reference cases in the research reactor IPEN/MB-01 located in São Paulo, Brazil. The staff of the group Reactor and Nuclear Power Studies (SERC) of CNEA, from the argentine side, performed calculations with deterministic models (HUEMUL-PUMA) and probabilistic methods (MCNP) modeling a great number of physical situations of de reactor, which previously have been studied and modeled by members of the Center of Nuclear Engineering of the IPEN, whose results were extensively provided to CNEA. In this paper results for critical configurations are shown. (author)

Cat, cougar, and jaguar spermatogenesis: a comparative analysis

Directory of Open Access Journals (Sweden)

Deiler Sampaio Costa

2006-09-01

Full Text Available This work presents a comparative review about the spermatogenic process in cats (Felis domestica, jaguars (Panthera onca and cougars (Puma concolor, with emphasis on testicular biometry, gonadossomatic index, volumetric proportion of testicular parenchyma components, tubular diameter, seminiferous epithelial height and seminiferous tubule length. It was an approach of the differences among the cell proportions that allowed conclusions about the overall yield of spermatogenic process and Sertoli cell index in three feline species.O processo espermatogênico do gato doméstico (Felis domestica, da onça-pintada (Panthera onca e da onça-parda (Puma concolor são analisados de forma comparativa, dando-se ênfase à biometria testicular, ao índice gonadossomático, à proporção volumétrica dos constituintes do parênquima testicular, ao diâmetro tubular, à altura do epitélio seminífero e ao comprimento dos túbulos seminíferos. Abordam-se ainda as diferenças entres as razões celulares que permitem conclusões sobre o rendimento do processo espermatogênico e índices de células de Sértoli das três espécies.

Implementación de un control fuzzy para el control cinemático directo en un robot manipulador Implementation of a fuzzy control for the direct kinematic control of a robot manipulator

Directory of Open Access Journals (Sweden)

D.A Tibaduiza

2011-12-01

Full Text Available En este artículo se muestra el desarrollo e implementación de la lógica difusa como herramienta de control de posición para cada una de las articulaciones de un robot tipo PUMA. Se hace una descripción general del robot y se muestra el cálculo del volumen de trabajo, el cual es usado para la fuzzificación en el desarrollo del controlador. Finalmente es mostrado el desarrollo y la simulación del controlador usando la toolbox fuzzy de Matlab, así como la descripción de una implementación realizada en un PLC.In this article, the development and implementation of a fuzzy logic system as position control tool of each one of the joints in a PUMA robot is shown. A general description, which include general descriptions about the robot as workspace and therefore the development of the strategy of control with the definition of the rules in the fuzzification process is also included. Finally are shown the development and simulation of the controller using the fuzzy control toolbox of Matlab and the description of a implementation in a PLC.

Estudo das representações sociais sobre gestação em mulheres bolivianas no contexto da atenção básica em saúde na área central da cidade de São Paulo Study on social representations of pregnancy in bolivian women in the context of primary health care in the central area of the city of São Paulo

Directory of Open Access Journals (Sweden)

Maria Carolina C. Madi

2009-06-01

Full Text Available O processo imigratório dos bolivianos para o Brasil vem trazendo muitos questionamentos e necessidades de intervenção pelos serviços de saúde na cidade de São Paulo. As barreiras impostas pela cultura boliviana (como a linguagem e o receio que os bolivianos têm pela situação de ilegalidade no país colocam aos serviços obstáculos no acesso à população. O objetivo dessa pesquisa é a compreensão das concepções das mulheres imigrantes bolivianas - que frequentam o Centro de Saúde Escola Barra Funda "Dr. Alexandre Vranjac" (CSEBF, na região central de São Paulo - sobre gestação, nos contextos: familiar, de adaptação como imigrantes e de espaço de construção da vida pessoal. Realizou-se uma análise qualitativa de entrevistas que incluíram mulheres bolivianas gestantes maiores de 18 anos, matriculadas no CSEBF. Foram realizadas algumas visitas domiciliares junto às agentes comunitárias. Como resultado, obteve-se que as bolivianas praticam endogamia e seus parceiros são fixos. Na Bolívia, não procuravam o serviço de saúde. Notou-se um paradoxo no que diz respeito à gravidez e ao trabalho, pois dizem ter planejado a primeira gestação, embora concordem que o trabalho - principal motivo da imigração - seja prejudicado pela gestação, parto e maternidade. Quanto à prática de parto, as bolivianas desejam e acreditam que o parto normal seja melhor que a cesárea, o que diverge do posicionamento comum das mulheres brasileiras. Este estudo poderá contribuir com conhecimentos sobre as concepções de saúde, particularmente sobre a gravidez, e acredita-se que as práticas dos serviços possam ser melhoradas, ampliando-se a capacidade de organização para receber imigrantes bolivianos.The process of Bolivian immigration to Brazil has been bringing questions and the necessity of intervention through the Health Services in the city of São Paulo. The barriers that come with the Bolivian culture (like the language and

La situación energética en el Pacto Andino

OpenAIRE

Centro de Estudios Sudamericanos

2008-01-01

Los países de la región han venido modernizando sus sectores energéticos y han adoptado enfoques similares en cuanto a objetivos generales como la búsqueda de la eficiencia mediante mecanismos de mercado donde ello sea posible; la tendencia al alejamiento del Estado de actividades puramente empresariales y su focalización en los temas de regulación y control; la puesta en marcha de políticas transparentes que promuevan la competencia; y la participación de inversionistas privados, etc. No obs...

Inmigrantes andinos en Madrid: Sus danzas y sus músicas tradicionales

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Lourdes Morales

2007-01-01

Full Text Available In our urban context we get in touch with people that have been forced to leave their countries under different circumstances in order to live in Spain. This article analyses their wish to maintain a group identity and how this identity is materialized by some individuals through traditional dance and music. The study is intended as a framework for subsequent educational investigations that relate that cultural reality with the situation in secondary schools where children of Latin American immigrants study.Nuestro entorno ciudadano inmediato nos pone en contacto diario con personas que por diferentes razones se han visto obligadas a dejar sus países de origen para instalarse en España. Este artículo analiza el deseo que surge en ellas de mantener una identidad de grupo, y cómo ésta se concreta en ciertos individuos mediante manifestaciones de danza y música popular tradicional. El estudio pretende servir de marco para ulteriores investigaciones educativas que vinculen esa realidad cultural con la situación de institutos de enseñanza secundaria en los que estudian hijos de inmigrantes latinoamericanos.

Grado de cobertura del muestreo de escarabajos coprófagos (Coleoptera: Scarabaeidae: Scarabaeinae en Colombia

Directory of Open Access Journals (Sweden)

Jorge Ari Noriega

2015-03-01

Full Text Available Una de las principales limitantes para generar estrategias para la conservación, es la falta de información y la dificultad para identificar vacíos de conocimiento, que faciliten el entendimiento de un grupo taxonómico. En este trabajo desarrollamos el diagnóstico sobre el grado de cobertura del muestreo de escarabajos coprófagos en Colombia. Se recopiló la bibliografía, utilizando 12 bases de datos y se revisaron 16 940 especímenes depositados en 26 colecciones. Se encontraron 232 especies, en 386 localidades, con un porcentaje de cobertura del 10.62%. Se evidencia en los últimos años un incremento en el número de estudios, sin embargo solo 64 localidades tienen publicaciones. Se encontraron registros para todos los departamentos, siendo los mejor muestreados: Cundinamarca, Antioquia, Valle del Cauca y Boyacá. Los ecosistemas con mayor número de publicaciones son el bosque húmedo premontano Andino, el bosque húmedo montano Andino y el bosque húmedo del Pacífico. Sin embargo, existen muchos ecosistemas con muy pocos estudios como los manglares, zonas desérticas, savanas naturales, morichales, páramos, bosques inundables y sistemas agrícolas. La región biogeográfica con mayor número de localidades es la Andina, seguida del Chocó-Magdalenense y la Amazonía. A nivel general, persiste un alto nivel de submuestreo. Se evidencia la necesidad de ampliar la cobertura del muestreo a nivel nacional, enfocando los esfuerzos en aquellas áreas submuestreadas con importancia a nivel de conservación.

Le travail des femmes à Frías: modèle andin et variante régionale

Directory of Open Access Journals (Sweden)

1993-01-01

Full Text Available À Frías, dans les Andes de Piura, les femmes sont absentes des tâches de production agricole au sens strict. Une comparaison avec des études menées dans d’autres régions montre en quoi cette organisation diffère d’un modèle andin. Mais ce modèle est trompeur. Il recouvre une grande variété de situations. Entre autres facteurs, la reconstitution du passé d’un système de production est nécessaire pour comprendre son orientation actuelle. EL TRABAJO DE LAS MUJERES EN FRÍAS: MODELO ANDINO Y VARIANTE REGIONAL. En Frías, en la sierra de Piura, las mujeres no participan en las tareas de producción agrícola en el sentido estricto. Una comparación con estudios realizados en otras regiones indica cómo esta organización difiere de un modelo andino. Pero, este modelo, que hemos construido, encubre una gran diversidad de casos. Entre otros factores, la reconstitución del pasado de un sistema de producción es necesaria para entender su orientación actual. WOMEN’ S WORK: ANDEAN PATTERN AND LOCAL VARIATION. Women are not present in agricultural working stricto sensu in Frías, in the Piura highlands. A comparison of the pattern of organization with case studies in other regions of Peru shows differences with the Andean pattern. But the pattern described here covers a great diversity of situations. Among many factors, the historical reconstitution of a farming system is necessary to understand its current orientation.

Puna Geothermal Venture Hydrologic Monitoring Program

Energy Technology Data Exchange (ETDEWEB)

None

1990-04-01

This document provides the basis for the Hydrologic Monitoring Program (HMP) for the Puna Geothermal Venture. The HMP is complementary to two additional environmental compliance monitoring programs also being submitted by Puma Geothermal Venture (PGV) for their proposed activities at the site. The other two programs are the Meteorology and Air Quality Monitoring Program (MAQMP) and the Noise Monitoring Program (NMP), being submitted concurrently.

Paleohidrología de los últimos 25000 años en los Andes bolivianos

Directory of Open Access Journals (Sweden)

1995-01-01

Full Text Available PALÉOHYDROLOGIE DES DERNIÈRES 25 000 ANNÉES DANS LES ANDES BOLIVIENNES. Nous présentons une reconstruction climatique de haute résolution de l’Altiplano bolivien (Andes Centrales basée sur des données géomorphologiques, sédimentologiques, palynologiques et provenant de l’analyse des faunes d’ostracodes. Nous avons déterminé (1, de manière semi-quantitative, la température ainsi que (2 de façon quantitative, les variations des niveaux lacustres depuis la fin du Pléistocène (25 000 ans BP. Les principaux résultats obtenus sont les suivants: de 25 000 à 18 000 ans BP, les températures atmosphériques sont basses ainsi que les niveaux des lacs entre 18 000 et 15 000/14 000 ans BP, la présence d’une lacune de sédimentation est indicatrice d’une phase climatique sèche pendant le Tardi-Glaciaire (15 000/14 000 - 10 500, les lacs (phase Tauca et les glaciers se sont étendus de 10 500 à 8000 ans BP, les lacs et les glaciers reculent très rapidement pendant que la température globale moyenne augmente à l’Holocène moyen (8 000-3 900 ans BP, le climat régional est globalement de type sec autour de 3900 ans BP, le niveau du lac Titicaca monte fortement des conditions relativement humides s’installent alors et se maintiennent par la suite pendant le Petit âge de la Glace (16ème-19ème siècles, des conditions froides et humides prévalent. En base a datos geomorfológicos, sedimentológicos, palinológicos y el análisis de fauna de ostrácodos, se ha determinado (1, de manera semicuantitativa, la temperatura así como (2 los cambios cuantificados de las variaciones de los niveles lacustres desde el final del Pleistoceno (25 000 años BP. Los principales resultados obtenidos son los siguientes: de 25 000 a 18 000 años BP, las temperaturas atmosféricas son bajas así como los niveles de los lagos entre 18 000 y 15 000/14 000 años BP, una fase climática seca es definida por la presencia de una laguna de sedimentación durante el Tardi-Glaciar (15 000/14 000 a 10 500 años BP, los lagos (fase Tauca y los glaciares se extendieron de 10 500 a 8 000 años BP, los lagos y los glaciares retroceden muy rápidamente mientras que la temperatura global media aumenta el Holoceno medio (8 000-3 900 años BP corresponde generalmente a un clima seco alrededor de 3 900 años BP, el nivel del lago Titicaca sube considerablemente luego se instalan condiciones relativamente húmedas durante la Pequeña Edad de Hielo (siglos XVI y XIX, prevalecen condiciones frías y húmedas. 25,000 YR BP PALEOHYDROLOGY OF THE BOLIVIAN ANDES. We report a high-resolution climate reconstruction for the Bolivian Altiplano (Central Andes based on geomorphological, sedimentological, palynological, and analysis of lacustrine ostracod shells. We determine (1 semi-quantitative changes in temperature and (2 quantitative changes in lake-levels from the late Pleistocene (25,000 yr BP to the present. The principal results are the following ones: from 25,000 to 18,000 yr BP, temparatures decreased as lake-levels lowered between 18,000 and 15,000/14,000 yr BP, a sedimentary hiatus indicates very low Lake Titicaca levels during the last deglaciation (15,000/14,000 , 10,500 yr BP, lake levels (Tauca phase and glaciers were consistently wide in the Altiplano and cordilleras from 10,500 to 8000 yr BP, lake levels declined and glaciers receded as global temperature increased during the mid-Holocene (8000-3900 yr BP a dry climate generally prevailed by 3900 yr BP, the lake level rose markedly and relatively moist conditions were established and persisted after during the Little Ice Age (16th-19th centuries, moist and cold conditions prevailed.

Pluralismo giuridico e pratica giuridica indigena: il caso dei Guaranì del Chaco Boliviano

Directory of Open Access Journals (Sweden)

Francesca Scionti

2017-03-01

Full Text Available This article ethnographically explores the form and the content of juridical practices of Guarani people living in the Capitanías of Charagua Norte and Alto Isoso, Bolivia. Starting from the Bolivian legal pluralism main field and through the analysis of some juridical case study, I answer some questions about how the Guarani people act and interpret the legal field in a plural legal context. I argue that such guarani people practice is both rooted in an interlegal field of sense and meaning and product of a legal and political strategy useful to hide and protect the indigenous juridical habitus.

[The jaguar Panthera onca (Carnivora: Felidae) in “El Cielo” Biosphere Reserve, Tamaulipas, Mexico].

Science.gov (United States)

Carrera-Treviño, Rogelio; Lira-Torres, Iván; Martínez-García, Luis; López-Hernández, Martha

2016-12-01

Information on the ecology of jaguars (Panthera onca) in “El Cielo” Biosphere Reserve in Tamaulipas, Mexico is scant and limited to anecdotic records in a handful of publications. The objectives of our study were to: a) determine population density and structure of jaguars, b) compare their activity patterns with that of pumas (Puma concolor), c) ascertain potential prey relative abundance, and d) evaluate local resident’s perception on loss of domestic animals due to jaguar predation. Between April 2013 and April 2014 we conducted camera trapping in Gomez Farias Township with a total sampling effort of 8 580 camera trap days. Besides, we completed 136 semi-structured interviews among local residents of Gomez Farias and Llera Townships to gather information on domestic animal losses attributed to jaguars and other carnivores. We identified eight different jaguar individuals during a complete year of camera-trapping, composed of four adult females, one juvenile female, two adult males and one juvenile male. We estimated a jaguar density of 5.9 ± 1.3 jaguars/100 km². Activity patterns for jaguars and pumas were similar as both were nocturnal and crepuscular in nature. The most abundant potential prey species for jaguars in the study site were Crax rubra, Cuniculus paca, Mazama temama, Odocoileus virginianus and Didelphis virginiana; while the rarest were Mephitis macroura and Procyon lotor. Interview results suggested that chickens, dogs, and house cats were the most consumed domestic animals from all reported losses by local residents (n= 107). This study represents the first attempt to describe jaguar ecology in “El Cielo” Biosphere Reserve; however, there is a need of additional monitoring efforts to determine the current status of jaguars in a larger area in order to establish conservation strategies. Finally, this jaguar population may have an important role in maintaining the species in the Sierra Madre Oriental biological corridor connecting

Persian shallot, Allium hirtifolium Boiss, induced apoptosis in human hepatocellular carcinoma cells.

Science.gov (United States)

Hosseini, Farzaneh Sadat; Falahati-Pour, Soudeh Khanamani; Hajizadeh, Mohammad Reza; Khoshdel, Alireza; Mirzaei, Mohammad Reza; Ahmadirad, Hadis; Behroozi, Reza; Jafari, Nesa; Mahmoodi, Mehdi

2017-08-01

This study investigated the potential of Persian shallot extract as an anticancer agent in HepG2 tumor cell line, an in vitro human hepatoma cancer model system. The inhibitory effect of Persian shallot on the growth of HepG2 cells was measured by MTT assay. To explore the underlying mechanism of cell growth inhibition of Persian shallot, the activity of Persian shallot in inducing apoptosis was investigated through the detection of annexin V signal by flow cytometry and expression of some apoptosis related genes such p21, p53, puma, caspase-8 family-Bcl-2 proteins like bid, bim, bcl-2 and bax were measured by real-time PCR in HepG2 cells. Persian shallot extract inhibited the growth of HepG2 cells in a dose-dependent manner. The IC 50 value (inhibiting cell growth by 50%) was 149 μg/ml. The results of real-time PCR revealed a significant up-regulation of bid, bim, caspase-8, puma, p53, p21 and bax genes and a significant downregulation of bcl-2 gene in HepG2 cells treated with Persian shallot extract significantly. Therefore, this is the first report on an increased expression of bid, bim, caspase-8, puma, p53, p21 and bax genes and down regulation of bcl-2 gene indicating that the Persian shallot extract possibly induced the process of cell death through the intrinsic and extrinsic apoptosis pathways and triggers the programmed cell death in HepG2 tumor cell lines by modulating the expression of pro-/anti-apoptotic genes. Furthermore, we showed that Persian shallot extract increased annexin V signal and expression, resulting in apoptotic cell death of HepG2 cells after 24 h treatment. Therefore, according to the results of this study, the Persian shallot extract could be considered as a potential candidate for production of drug for the prevention or treatment of human hepatoma.

Weather and Prey Predict Mammals' Visitation to Water.

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Grant Harris

Full Text Available Throughout many arid lands of Africa, Australia and the United States, wildlife agencies provide water year-round for increasing game populations and enhancing biodiversity, despite concerns that water provisioning may favor species more dependent on water, increase predation, and reduce biodiversity. In part, understanding the effects of water provisioning requires identifying why and when animals visit water. Employing this information, by matching water provisioning with use by target species, could assist wildlife management objectives while mitigating unintended consequences of year-round watering regimes. Therefore, we examined if weather variables (maximum temperature, relative humidity [RH], vapor pressure deficit [VPD], long and short-term precipitation and predator-prey relationships (i.e., prey presence predicted water visitation by 9 mammals. We modeled visitation as recorded by trail cameras at Sevilleta National Wildlife Refuge, New Mexico, USA (June 2009 to September 2014 using generalized linear modeling. For 3 native ungulates, elk (Cervus Canadensis, mule deer (Odocoileus hemionus, and pronghorn (Antilocapra americana, less long-term precipitation and higher maximum temperatures increased visitation, including RH for mule deer. Less long-term precipitation and higher VPD increased oryx (Oryx gazella and desert cottontail rabbits (Sylvilagus audubonii visitation. Long-term precipitation, with RH or VPD, predicted visitation for black-tailed jackrabbits (Lepus californicus. Standardized model coefficients demonstrated that the amount of long-term precipitation influenced herbivore visitation most. Weather (especially maximum temperature and prey (cottontails and jackrabbits predicted bobcat (Lynx rufus visitation. Mule deer visitation had the largest influence on coyote (Canis latrans visitation. Puma (Puma concolor visitation was solely predicted by prey visitation (elk, mule deer, oryx. Most ungulate visitation peaked during

Weather and Prey Predict Mammals’ Visitation to Water

Science.gov (United States)

Harris, Grant; Sanderson, James G.; Erz, Jon; Lehnen, Sarah E.; Butler, Matthew J.

2015-01-01

Throughout many arid lands of Africa, Australia and the United States, wildlife agencies provide water year-round for increasing game populations and enhancing biodiversity, despite concerns that water provisioning may favor species more dependent on water, increase predation, and reduce biodiversity. In part, understanding the effects of water provisioning requires identifying why and when animals visit water. Employing this information, by matching water provisioning with use by target species, could assist wildlife management objectives while mitigating unintended consequences of year-round watering regimes. Therefore, we examined if weather variables (maximum temperature, relative humidity [RH], vapor pressure deficit [VPD], long and short-term precipitation) and predator-prey relationships (i.e., prey presence) predicted water visitation by 9 mammals. We modeled visitation as recorded by trail cameras at Sevilleta National Wildlife Refuge, New Mexico, USA (June 2009 to September 2014) using generalized linear modeling. For 3 native ungulates, elk (Cervus Canadensis), mule deer (Odocoileus hemionus), and pronghorn (Antilocapra americana), less long-term precipitation and higher maximum temperatures increased visitation, including RH for mule deer. Less long-term precipitation and higher VPD increased oryx (Oryx gazella) and desert cottontail rabbits (Sylvilagus audubonii) visitation. Long-term precipitation, with RH or VPD, predicted visitation for black-tailed jackrabbits (Lepus californicus). Standardized model coefficients demonstrated that the amount of long-term precipitation influenced herbivore visitation most. Weather (especially maximum temperature) and prey (cottontails and jackrabbits) predicted bobcat (Lynx rufus) visitation. Mule deer visitation had the largest influence on coyote (Canis latrans) visitation. Puma (Puma concolor) visitation was solely predicted by prey visitation (elk, mule deer, oryx). Most ungulate visitation peaked during May and

Horacio Durán, Italo Pedrotti, Charango Method – Método de Charango, Mel Bay Publications, INC, Noviembre 2010, 208 p.

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Léonardo Garcia

2010-11-01

Full Text Available La edición de métodos dedicados a la ejecución de instrumentos musicales andinos populares ha sido generalmente escasa en comparación su grado de difusión discográfica y a su proyección musical.   La mayoría de las obras editadas remontan a un período relativamente reciente (años 1960, asociándose a las diversas experiencias folk de esa época (Ej. “nueva canción latinoamericana”. Sin embargo, hasta los años 1990 la reticencia a la escritura en este ámbito pareciera primar. Podríamos mencion...

Red de Noticias vía satélite. Diógenes y el reto de América Latina

OpenAIRE

Nell Thomas

2015-01-01

Los sistemas de intercambio de noticias existentes fueron desarrolladas en una época en la cual la capacidad de satélites era escasa y costosa. Ahora los procesos de integración se han acelerado. En América Latina se puede constatar que los procesos de integración son muy dinámicos en el Cono Sur, en los países andinos y también en América Central. Con el surgimiento de TLC, gigante económico, la necesidad de mayor información ha crecido porque sin información no se puede dar a la integración...

Valorización de la empresa Unión Andina de Cementos S.A.A. (UNACEM S.A.A.)

OpenAIRE

Cárdenas Zúñiga, Julissa Yasmet; Zapana Solórzano, Edson Humberto; Puell Escobedo, Percy Alejandro

2016-01-01

Unión Andina de Cementos S.A.A. (UNACEM S.A.A.) es la cementera líder en el Perú con más de 60 años en el mercado. Es una empresa formada el 25 de julio del 2012 a partir de la fusión de dos empresas cementeras (Cementos Lima fundada en 1967, y Cemento Andino creada en 1952). Su actividad se centra en producir cemento en el Perú y en el extranjero, incluyendo su comercialización y venta. Se muestra el valor de la empresa UNACEM mediante el uso de dos modelos: el método de descuento del flujo ...

LI, Fabiana. Unearthing conflict: corporate mining, activism, and expertise in Peru. Durham: Duke University Press, 2015. 265 p.

OpenAIRE

Peñafiel, Adriana Paola Paredes

2015-01-01

Este livro é o produto da pesquisa de mestrado e doutorado da antropóloga Fabiana Li em dois lugares emblemáticos na questão de conflitos mineiros no Peru: La Oroya no centro andino e Cajamarca ao norte dos Andes peruanos. O primeiro é um complexo metalúrgico que funciona desde os inícios do século XX e que a partir de 1997 está sob o comando da empresa americana Doe Run. O segundo é a cidade de Cajamarca, onde está localizada a maior jazida de ouro da América do Sul, Yanacocha, operada pela ...

¿Nuevos sujetos subalternos? ¡No en la nación cercada! Del “Informe sobre Uchuraccay” de Mario Vargas Llosa a Madeinusa de Claudia Llosa

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Juan Carlos Ubilluz Raygada

2014-06-01

Full Text Available Madeinusa (2006, la ópera prima de Claudia Llosa, es una de las películas peruanas más exitosas en el exterior; ha ganado festivales de cine en Europa y Estados Unidos. Pero también es la película que ha suscitado uno de los debates más candentes en el medio nacional. El debate gira en torno a la representación del mundo andino y de sus habitantes. A fin de entender el porqué de su carácter encendido, dediquemos de entrada algunas líneas al espacio y al tiempo de la película.

Efecto de gelificantes en la formulación de dulce de yacón

OpenAIRE

Maldonado,Silvina; Singh,Judith del Carmen

2008-01-01

El yacón (Smallanthus sonchifolius) es un tubérculo andino cultivado en las laderas de los Andes. Es una planta perenne que llega a su madurez entre 6-7 meses hasta 1 año, según la altura sobre el nivel del mar. Este trabajo propone la formulación de un producto alimenticio a partir de yacón por agregado de solutos: glucosa y sacarosa y combinación de barreras de estrés. Se estudió el efecto de gelificantes: agar-agar, pectina y goma arábiga, en tres concentraciones: 0,30, 0,41 y 0,48%. Se ag...

Efecto de gelificantes en la formulación de dulce de yacón Efeito de gelificante na formulação do doce do yacon

OpenAIRE

Silvina Maldonado; Judith del Carmen Singh

2008-01-01

El yacón (Smallanthus sonchifolius) es un tubérculo andino cultivado en las laderas de los Andes. Es una planta perenne que llega a su madurez entre 6-7 meses hasta 1 año, según la altura sobre el nivel del mar. Este trabajo propone la formulación de un producto alimenticio a partir de yacón por agregado de solutos: glucosa y sacarosa y combinación de barreras de estrés. Se estudió el efecto de gelificantes: agar-agar, pectina y goma arábiga, en tres concentraciones: 0,30, 0,41 y 0,48%. Se ag...

Comunidad Andina y negocios internacionales: una visión desde su institucionalidad y supranacionalidad

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Luis Nelson Beltrán Mora

2013-03-01

Full Text Available Rev.esc.adm.neg Este trabajo, presenta la evolución de la integración de la Comunidad Andina (CAN desde la perspectiva del derecho internacional; se deduce que el Sistema de Integración Andino (SAI, no sólo ha permitido la promoción de los negocios sino que el Derecho Comunitario (DC desarrollado en el grupo, blinda los tratados comerciales dando institucionalidad y supranacionalidad a la CAN, al punto de convertirse en referencia para imitarlo en la reciente creada Unión de Naciones del Sur (UNASUR. En la CAN, el nuevo regionalismo abierto genera incertidumbre sobre el futuro de dicho bloque.

Turismo, geografía, globalización. Una multitud de combinaciones por explorar

OpenAIRE

Raymond, Nathalie

2013-01-01

De París a Lima: los orígenes de un tema de investigación Cuando hace 10 años, durante una conversación, Olivier Dollfus me habló por primera vez de la posibilidad de solicitar una beca de investigación al Instituto Francés de Estudios Andinos de Lima para llevar a cabo una tesis de doctorado, yo no conocía ni la existencia de estos centros de investigación franceses en el extranjero ni América Latina. Mis estudios secundarios me habían orientado hacia el aprendizajedel alemán y no del castel...

PUMA: a puzzle piece in chloroquine?s antimelanoma activity

OpenAIRE

Amaravadi, Ravi K.

2013-01-01

Chloroquine can induce cell death in a subset of cancer cell lines, and some melanoma cell lines are quite susceptible. While it is well known that chloroquine impairs lysosomal function and can serve as an autophagy inhibitor, the molecular target of chloroquine and the subsequent cascade of events that leads to cell death are not fully understood. Recent evidence indicates that in melanoma cell lines, chloroquine induces apoptosis by preventing degradation of the pro-apoptotic BH3-only prot...

The Role of BRCA1 Domains and Motifs in Tumor Suppression

Science.gov (United States)

2011-08-01

George C. Prendergast Thomas Jefferson University Carol Prives Columbia University Martin Raff University College London E. Premkumar Reddy Temple...71] Taron, M.; Rosell, R.; Felip, E.; Mendez , P.; Souglakos, J.; Ronco, M.S.; Queralt, C.; Majo, J.; Sanchez, J.M.; Sanchez, J.J.; Maestre, J...Skrzypski, M.; Jassem, E.; Taron, M.; Bartolucci, R.; Sanchez, J.J.; Mendez , P.; Chaib, I.; Perez-Roca, L.; Szymanowska, A.; Rzyman, W.; Puma, F

FOXO3a Provides a Quickstep from Autophagy Inhibition to Apoptosis in Cancer Therapy.

Science.gov (United States)

Codogno, Patrice; Morel, Etienne

2018-03-12

FOXO3a, a member of the Forkhead transcription factor family, has roles in apoptosis and autophagy. In this issue of Developmental Cell, Fitzwalter et al. (2018) describe how the blockade of FOXO3a turnover, which normally occurs through autophagy, sensitizes cancer cells to apoptosis through FOXO3a-mediated stimulation of pro-apoptotic PUMA/BBC3 expression. Copyright © 2018 Elsevier Inc. All rights reserved.

Study of Helicopter Performance and Terminal Instrument Procedures

Science.gov (United States)

1980-06-01

possible employment of decelerating or other innovative approaches to be discussed in Section 3 and may be employed to advantage in reviewing missed...330J Puma is a 19 passenger medium helicopter manufactured by Societe Nationale Industrielle Aerospatiale of Marignane, France and marketed in the...for use by the French and British armed forces. It is manufactured by the Helicopter Divison of Societe Nationale Industrielle Aerospatiale of Marignane

Validation of Neutron Calculation Codes and Models by means of benchmark cases in the frame of the Binational Commission of Nuclear Energy. Probabilistic Models

International Nuclear Information System (INIS)

Dos Santos, Adimir; Siqueira, Paulo de Tarso D.; Andrade e Silva, Graciete Simões; Grant, Carlos; Tarazaga, Ariel E.; Barberis, Claudia

2013-01-01

In year 2008 the Atomic Energy National Commission (CNEA) of Argentina, and the Brazilian Institute of Energetic and Nuclear Research (IPEN), under the frame of Nuclear Energy Argentine Brazilian Agreement (COBEN), among many others, included the project “Validation and Verification of Calculation Methods used for Research and Experimental Reactors . At this time, it was established that the validation was to be performed with models implemented in the deterministic codes HUEMUL and PUMA (cell and reactor codes) developed by CNEA and those ones implemented in MCNP by CNEA and IPEN. The necessary data for these validations would correspond to theoretical-experimental reference cases in the research reactor IPEN/MB-01 located in São Paulo, Brazil. The staff of the group Reactor and Nuclear Power Studies (SERC) of CNEA, from the argentine side, performed calculations with deterministic models (HUEMUL-PUMA) and probabilistic methods (MCNP) modeling a great number of physical situations of de reactor, which previously have been studied and modeled by members of the Center of Nuclear Engineering of the IPEN, whose results were extensively provided to CNEA. In this paper results of comparison of calculated and experimental results for critical configurations, temperature coefficients, kinetic parameters and fission rates evaluated with probabilistic models spatial distributions are shown. (author)

Validation of Neutron Calculation Codes and Models by means of benchmark cases in the frame of the Binational Commission of Nuclear Energy. Kinetic Parameters, Temperature Coefficients and Power Distribution

International Nuclear Information System (INIS)

Dos Santos, Adimir; Siqueira, Paulo de Tarso D.; Andrade e Silva, Graciete Simões; Grant, Carlos; Tarazaga, Ariel E.; Barberis, Claudia

2013-01-01

In year 2008 the Atomic Energy National Commission (CNEA) of Argentina, and the Brazilian Institute of Energetic and Nuclear Research (IPEN), under the frame of Nuclear Energy Argentine Brazilian Agreement (COBEN), among many others, included the project “Validation and Verification of Calculation Methods used for Research and Experimental Reactors . At this time, it was established that the validation was to be performed with models implemented in the deterministic codes HUEMUL and PUMA (cell and reactor codes) developed by CNEA and those ones implemented in MCNP by CNEA and IPEN. The necessary data for these validations would correspond to theoretical-experimental reference cases in the research reactor IPEN/MB-01 located in São Paulo, Brazil. The staff of the group Reactor and Nuclear Power Studies (SERC) of CNEA, from the argentine side, performed calculations with deterministic models (HUEMUL-PUMA) and probabilistic methods (MCNP) modeling a great number of physical situations of de reactor, which previously have been studied and modeled by members of the Center of Nuclear Engineering of the IPEN, whose results were extensively provided to CNEA. In this paper results of comparison of calculated and experimental results for temperature coefficients, kinetic parameters and fission rates spatial distributions are shown. (author)

Lack of response of an open-habitat ungulate to the presence of predator urine La falta de la respuesta de un ungulado de habitat abierto a la presencia de orina de depredadores

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RONALD J SARNO

2008-06-01

Full Text Available The behavioral response of ungulates to the presence of odors associated with dangerous predators has received some attention, yet little is known about how predominantly open-habitat ungulates react to the presence of predator scents. We investigated the behavioral responses of a predominantly open-habitat ungulate, the guanaco, Lama guanicoe, when exposed to the urine of various predators. Guanacos only reacted to the urine of mountain lions (native predator, Puma concolor, in one trial. The lack of a response to predator urine may indicate that guanacos generally rely on visión more than olfaction for predator detection.La respuesta conductual de ungulados a la presencia de olores asociados a depredadores ha recibido algo de atención, pero aún se sabe poco sobre cuan predominantemente los ungulados de habitat abiertos reaccionan a la presencia de olores de depredadores. Examinamos las respuestas conductuales del guanaco, Lama guanicoe, cuando estos animales estaban expuestos a orina de varios depredadores. Los guanacos solo reaccionaron a la presencia de la orina del puma en uno de los ensayos. La ausencia de respuesta registrada podría indicar que los guanacos utilizan más la visión que el olfato para detectar a sus depredadores.

A SURVEY ON MULTICAST ROUTING PROTOCOLS FOR PERFORMANCE EVALUATION IN WIRELESS SENSOR NETWORK

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A. Suruliandi

2015-03-01

Full Text Available Multicast is a process used to transfer same message to multiple receivers at the same time. This paper presents the simulation and analysis of the performance of six different multicast routing protocols for Wireless Sensor Network (WSN. They are On Demand Multicast Routing Protocol (ODMRP, Protocol for Unified Multicasting through Announcement (PUMA, Multicast Adhoc On demand Distance Vector Protocol (MAODV, Overlay Boruvka-based Adhoc Multicast Protocol (OBAMP, Application Layer Multicast Algorithm (ALMA and enhanced version of ALMA (ALMA-H for WSN. Among them, ODMRP, MAODV and PUMA are reactive protocols while OBAMP, ALMA and ALMA-H are proactive protocols. This paper compares the performance of these protocols with common parameters such as Throughput, Reliability, End-to-End delay and Packet Delivery Ratio (PDR with increasing the numbers of nodes and increasing the speed of the nodes. The main objective of this work is to select the efficient multicast routing protocol for WSN among six multicast routing protocol based on relative strength and weakness of each protocol. The summary of above six multicast routing protocols is presented with a table of different performance characteristics. Experimental result shows that ODMRP attains higher throughput, reliability and higher packet delivery ratio than other multicast routing protocol, while incurring far less end-to-end delay.

Characterisation in vivo of ways of induced deaths by p53, in the male germinal cells; Caracterisation in vivo des voies de mort induites par la p53, dans les cellules germinales males

Energy Technology Data Exchange (ETDEWEB)

Coureuil, M

2006-10-15

The male germinal cells constitute a heterogeneous cell population including pre-meiotic proliferating cells (spermatogonia) and meiotic cells and post meiotic cells in differentiation (spermatocytes and spermatids). We study the involvement in vivo of the p53 protein in the death of these cells with the help of two models, (1) a transgenic model of infertility, MTp53, in which the p53 is over expressed in the differentiated cells and induced their death, (2) the response of these cells to gamma irradiation, where only the spermatogonia die by apoptosis dependent of p53. We showed that the caspases (cysteine-aspartic proteases) are involved in the terminal differentiation of normal germinal cells. But in the MTp53 model, the p53 induces the death of differentiated cells via the activation of calpains and not of caspases. We studied the response of spermatogonia, to gamma irradiation by a transcriptomic approach, by DNA chips and semi-quantitative RT-PCR. we showed that the puma and dr5 genes are induced by the p53 after irradiation. more, the study of mice invalidated for trail ( the dr5 ligand) or for puma, allowed to demonstrate that the two effectors are essential to the activation of intrinsic and extrinsic ways of apoptosis. (N.C.)

Characterisation in vivo of ways of induced deaths by p53, in the male germinal cells

International Nuclear Information System (INIS)

Coureuil, M.

2006-10-01

The male germinal cells constitute a heterogeneous cell population including pre-meiotic proliferating cells (spermatogonia) and meiotic cells and post meiotic cells in differentiation (spermatocytes and spermatids). We study the involvement in vivo of the p53 protein in the death of these cells with the help of two models, (1) a transgenic model of infertility, MTp53, in which the p53 is over expressed in the differentiated cells and induced their death, (2) the response of these cells to gamma irradiation, where only the spermatogonia die by apoptosis dependent of p53. We showed that the caspases (cysteine-aspartic proteases) are involved in the terminal differentiation of normal germinal cells. But in the MTp53 model, the p53 induces the death of differentiated cells via the activation of calpains and not of caspases. We studied the response of spermatogonia, to gamma irradiation by a transcriptomic approach, by DNA chips and semi-quantitative RT-PCR. we showed that the puma and dr5 genes are induced by the p53 after irradiation. more, the study of mice invalidated for trail ( the dr5 ligand) or for puma, allowed to demonstrate that the two effectors are essential to the activation of intrinsic and extrinsic ways of apoptosis. (N.C.)

Linajes mitocondriales en muestras de esquina de Huajra (Jujuy, Argentina. Aportes al estudio de la ocupación incaica en la región y la procedencia de sus habitantes

Directory of Open Access Journals (Sweden)

María Russo

2016-12-01

Full Text Available El sitio arqueológico Esquina de Huajra (centrosur de la Quebrada de Humahuaca corresponde a una instalación ubicada cronológicamente en la Fase Inca (ca. 500-420 AP y la tradicionalmente asignada en el noroeste argentino como Hispano Indígena o de primeros contactos con el español (ca. 420-320 AP. Enmarcado en la política económica incaica, habría sido clave en la explotación y distribución de bienes procedentes de las Yungas Orientales. Además, su cultura material sugiere importantes redes de interacción con las tierras altas, planteando interrogantes sobre la conformación poblacional de sus habitantes.En este trabajo se analizan los linajes maternos de individuos de Esquina de Huajra en comparación con otros sitios del centro-sur andino para evaluar su posible origen foráneo, considerando que el reasentamiento de poblaciones fue una práctica imperial recurrente. El ADN fue extraído de piezas dentales de 6 individuos. Se secuenció la Región Hipervariable I del ADN mitocondrial en cuatro individuos hallándose dos A2 y dos C1. La ausencia de B2 discrepa con lo descripto para gran parte de los sitios andinos, donde este haplogrupo es mayoritario. Dos de los cuatro haplotipos se comparten únicamente con otros sitios de la Quebrada de Humahuaca del Período de Desarrollos Regionales (Los Amarillos y San José; pero una variante nodal C1 fue reportada tanto en Juella como en sitios peruanos preincaicos e incaicos. Estos resultados representan un primer aporte al estudio genético de los habitantes de Esquina de Huajra y una evidencia más de los complejos procesos poblacionales en la región andina.

El tarwi o chocho: una de las principales fuentes de proteína vegetal de las comunidades indígenas de los Andes Centrales

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Planchuelo, Ana M.

2005-01-01

Full Text Available El lupino andino (Lupinus mutabilis Sweet conocido también como tarwi o chocho, es una especie de leguminosa nativa de los Andes Centrales. Su domesticación se remonta a los principios de la cultura Nazca y desde ese entonces hasta la actualidad el cultivo está ampliamente difundido en las laderas montañosas y en los altos valles de Ecuador, Perú y Bolivia. La importancia del lupino para las comunidades andinas prehispánicas quedo documentada en pinturas de cerámicas y en tributos encontrados en tumbas de 100-150 años AC. Diversas técnicas de lavado y de mejoramiento vegetal fueron aplicadas desde la antigüedad para eliminar los alcaloides tóxicos que le confieren el sabor amargo a la planta y los granos. El tarwi, el maíz. los frijoles, los pseudocereales, quinoa y amaranto y la papa junto a otras raíces y tubérculos constituyen la comida básica de muchas culturas andinas. El objetivo de este trabajo fue determinar los componentes nutricionales de los granos del lupino andino para compararlos con los otros constituyentes de la dieta de las comunidades campesinas. Se analizaron por medio de técnicas fitoquímicas distintas variedades de tarwi. Se determinaron los contenidos de proteínas y grasas y los patrones de ácidos grasos. Los resultados muestran que la ingesta de lupinos, que provee un buen balance de proteínas y grasas en combinación con el maíz y los tubérculos, que aportan los hidratos de carbono, forman una dieta balanceada y de alto valor nutricional.

Then Fandango Complex in the Spanish Atlantic: a Panoramic View

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Peter Manuel

2015-01-01

Full Text Available Así como las formas andaluzas más conocidas del fandango muestran ciertos rasgos musicales distintivos, que pueden servir para vincular estos subgéneros, histórica y estructuralmente, a grupos mucho más amplios de las familias musicales transatlánticas, como el fandango popular y el semiclásico del siglo XVIII, géneros anteriores como la zarabanda y la chacona, la amplia familia de patrón ternario de la cuenca del Caribe, además de otros géneros andinos y sudamericanos. Mientras tanto, existen diferencias claras entre el complejo del fandango y otras familias importantes en el Atlántico español.

"Piores que bestas feras": Garcilaso de la Vega e o imaginário hispano-inca sobre os Guarani Chiriguano

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Protasio Paulo Langer

Full Text Available No presente artigo propomos uma análise do imaginário de Garcilaso de la Vega sobre os Chiriguano - povo guarani falante que, por volta do século XV, se estabeleceu nas fronteiras do império andino. O tenaz enfrentamento que travaram contra os exércitos imperiais incaicos e, posteriormente, contra os hispânicos ensejou que o cronista Garcilaso de la Vega descrevesse os Chiriguano como a antítese da civilização. Nossa análise incide sobre como esse cronista mestiço abordou os Chiriguano, no intuito de tecer similaridades entre o imaginário cristão e o inca.

Germán Rodas Chaves. Eloy Alfaro y Cuba en el Siglo XIX. La Habana: Fondo Editorial Casa de las Américas, 2013. 218 páginas.

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René Villaboy Zaldivar

2015-01-01

Full Text Available A propósito de que la República del Ecuador fuera el país invitado de honor a la XXIII Feria Internacional del Libro de la Habana, numerosas ediciones relacionadas con la literatura, el arte, la historia, la política y, en general, sobre la rica cultura del país andino vieron la luz en febrero de 2014. A una de ellas dedico este comentario. Se trata de Eloy Alfaro y Cuba en el siglo XIX, del historiador ecuatoriano Germán Rodas Chaves, publicada con excelente factura dentro de la colección investigaciones del Fondo Editorial de la Casa de las Américas.

Jícama: Producto con Identidad Territorial

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Marisol Idrovo Avecillas

2015-11-01

La jícama es un producto con identidad territorial (PIT, son fragmentos de la perspectiva de tierras aptas para el cultivo, producción, comercialización sostenible que se apega al Plan Nacional del Buen Vivir, que se ajusta al cambio de la Matriz Productiva incluyendo a los sectores involucrados del país, este vegetal andino no es consumido regularmente por los ecuatorianos; los resultados obtenidos en el laboratorio nos indican que es un vegetal rico en: grasa, proteína, humedad, fibra dietética, carbohidratos totales, energía total, energía de la grasa, hierro, sodio, potasio, calcio, vitaminas, entre otras propiedades.

Point kinetics improvements to evaluate three-dimensional effects in transients calculation

International Nuclear Information System (INIS)

Castellotti, U.

1987-01-01

A calculation method, which considers the flux axial perturbations in the parameters related to the reactivity within a point kinetics model, is described. The method considered uses axial factors of consideration which act on the thermohydraulic variables included in the reactivity calculation. The PUMA three-dimensional code as reference model for the comparisons, is used. The limitations inherent to the reactivity balance of the point models used in the transients calculation, are given. (Author)

Comparing the personality of three well-known sporting brands in Iran

OpenAIRE

Mohmood Mohammadian; Hamidreza Asgari Dehabadi

2012-01-01

A significant amount of literature specifies that there are benefits for having a favorable brand personality, such as purchase intentions and enhanced brand attitudes and higher degrees of consumer trust and loyalty. Brand differentiation is one of most important issues to handle competition in the hostile marketplace. A reliable solution for establishing the distinctiveness of a brand is through brand personality. This study analyzes the personality of Adidas, Nike and Puma brands in Iran u...

Bolivia-Brazil gas line route detailed

International Nuclear Information System (INIS)

Anon.

1992-01-01

This paper reports that state oil companies of Brazil and Bolivia have signed an agreement outlining the route for a 2,270 km pipeline system to deliver natural gas from Bolivian fields to Southeast Brazil. The two sides currently are negotiating details about construction costs as well as contract volumes and prices. Capacity is projected at 283-565 MMcfd. No official details are available, but Roberto Y. Hukai, a director of the Sao Paulo engineering company Jaako Poyry/Technoplan, estimates transportation cost of the Bolivian gas at 90 cents/MMBTU. That would be competitive with the price of gas delivered to the Sao Paulo gas utility Comgas, he the. Brazil's Petroleos Brasileiro SA estimates construction of the pipeline on the Brazilian side alone with cost $1.2-1.4 billion. Bolivia's Yacimientos Petroliferos Fiscales Bolivianos (YPFB) is negotiating with private domestic and foreign investors for construction of the Bolivian portion of the project

Una base impermeabilizante de los populismos: Bolivia y su historia reciente

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María Teresa Pinto Ocampo

2006-01-01

Full Text Available El artículo analiza la idea de la presencia de líderes populistas exitosos en Bolivia en años recientes. Desarrolla la idea de que en Bolivia no hay incentivos estructurales para que se desarrolle un líder populista debido al hecho de que los populistas no crecen en un contexto de extrema organización popular independiente. En la primera parte presenta una discusión sobre el marco teórico de la noción de populismo y de la definición del autor; la segunda parte presenta el caso del populismo boliviano analizando los elementos históricos que contribuyen a la ausencia del mismo hoy (especialmente el tipo de gobernability y el tipo de inclusión y el mecanismo que evita que Bolivia tenga un líder populista con presencia en un sector de la sociedad fuertemente organizado

Ropas americanas: Comercio, contrabando y compradores de ropa usada en la frontera de Corumbá, Brasil, y Puerto Quijarro, Bolivia

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ALBERO HERNÁNDEZ HERNÁNDEZ

2017-01-01

Full Text Available Este artículo analiza la comercialización y venta de ropa usada en la frontera entre Bolivia y Brasil, la cual atraviesa un proceso de traslado por varios países, medios de transporte, contra - bando, reúsos y resignif icación de vestimentas. a f inales del siglo xx , el comercio de ropa usada adquiere mayor importancia con la incorporación de onG norteamericanas y europeas, quienes recaudan estas mercancías en calidad de donativos para reenviarlas y comercializarlas en países sudamericanos. l as ropas usadas realizan extensos recorridos hasta los puertos chilenos, para después iniciar un trayecto por tren, y otros medios de transporte, rumbo al este boliviano fronterizo con Brasil. Puerto Quijarro, Bolivia, y c orumbá, Brasil, representan una experiencia de intercambio cultural y comercial, donde el contrabando y la compra y venta de ropa usada son parte de su interacción cotidiana.

2009 South American benchmarking study: natural gas transportation companies

Energy Technology Data Exchange (ETDEWEB)

Jordan, Nathalie [Gas TransBoliviano S.A. (Bolivia); Walter, Juliana S. [TRANSPETRO, Rio de Janeiro, RJ (Brazil)

2009-07-01

In the current business environment large corporations are constantly seeking to adapt their strategies. Benchmarking is an important tool for continuous improvement and decision-making. Benchmarking is a methodology that determines which aspects are the most important to be improved upon, and it proposes establishing a competitive parameter in an analysis of the best practices and processes, applying continuous improvement driven by the best organizations in their class. At the beginning of 2008, GTB (Gas TransBoliviano S.A.) contacted several South American gas transportation companies to carry out a regional benchmarking study in 2009. In this study, the key performance indicators of the South American companies, whose reality is similar, for example, in terms of prices, availability of labor, and community relations, will be compared. Within this context, a comparative study of the results, the comparative evaluation among natural gas transportation companies, is becoming an essential management instrument to help with decision-making. (author)

Migración sur-sur: factores relacionales e inserción segmentada de la población boliviana y peruana en la ciudad de Córdoba, Argentina

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Eduardo León Bologna

2016-01-01

Full Text Available Como caso de migración sur-sur se analizan las poblaciones de origen boliviano y peruano residentes en la ciudad de Córdoba, con la hipótesis del mayor peso explicativo de factores relacionales respecto de las diferencias de desarrollo entre las regiones de origen y destino. Se comparan la estructura demográfica, la inserción educativa y la distribución espacial de las dos poblaciones entre los censos nacionales de 2001 y 2010. Por razones de disponibilidad de los datos la inserción ocupacional sólo se describe en el censo de 2001, y a través de los antecedentes por medio de encuestas para el periodo siguiente. Se concluye que el atractivo de Córdoba se debe más a los vínculos históricos que estos dos colectivos migrantes han forjado con la ciudad que al nivel de desarrollo económico o social de ésta.

Uma nova espécie do gênero Temnomastax (Temnomastacinae, Eumastacidae, Orthoptera da Amazônia

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Renan S. Olivier

2014-12-01

Full Text Available O gênero Temnomastax apresenta atualmente sete espécies, sendo amplamente distribuídas pelo domínio Cerrado, na América do Sul. Neste trabalho, uma oitava espécie, Temnomastax spielmanni sp. nov., é descrita para a região Amazônica brasileira. A diagnose da nova espécie baseia-se em caracteres do complexo fálico e em características morfológicas externas. Temnomastax spielmanni sp. nov. apresenta semelhança com Temnomastax beni Rehn & Rehn, 1942, que ocorre em território boliviano, mas pode ser diferenciada por alguns caracteres externos. O complexo fálico de T. spielmanni sp. nov. apresenta caracteres ainda não descritos em Temnomastacinae; tal fato reforça a necessidade da revisão taxonômica dessa subfamília, o que poderá esclarecer as relações filogenéticas existentes.

Flower colour variation and chromosome numbers in the north western distributional area of Turners sidoides (Turneraceae

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Viviana G. Solís Neffa

2004-01-01

Full Text Available In the context of the evolutionary studies that are being carried out in Turners sidoides autopolyploid complex (x= 7, a systematic survey was made in the northwestern area (Bolivia of its distribution. Six populations with salmon flowers and thirty five with yellow ones of the subsp. pinnatifida were found. The distribution of these populations is associated with climatic and spatial variables. The populations with salmon flowers live in the dry forests (Chaco Boreal Biogeographical Province, while yellow flowered populations occur in the inter-andean valleys (Boliviano-Tucumana Biogeographical Province. All the population studied are diploid. The results obtained support the allopatric diversification model of populations with yellow and salmon flowers at the diploid level, probably favoured by the orographic barriers and climatic changes that have arisen during the Andes development and Quaternary glaciations. Moreover, our analysis evidences that the north western area of T. sidoides constitutes an important centre of variation of the subsp. pinnatifida and the major centre of diploids hitherto detected

Percepciones de los equipos de salud en torno a las mujeres migrantes bolivianas y peruanas en la ciudad de Córdoba

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Lila Aizenber

2015-01-01

Full Text Available Este artículo analiza las percepciones que se construyen desde los equipos de saluden torno a las mujeres migrantes de origen peruano y boliviano en la ciudad de Cór-doba, Argentina. La investigación consistió en un estudio cualitativo, exploratorioy descriptivo con base en 12 entrevistas en profundidad realizadas con una guía depautas semiestructuradas. El trabajo muestra las ideas que los equipos tienen sobrelos dos grupos migrantes, así como sus opiniones respecto a los factores que influ-yen en el acceso y uso de las mujeres a los sistemas de salud durante el proceso deembarazo y parto. Se enfatiza sobre la importancia de incorporar una perspectivahistórico-política y cultural en la atención de los migrantes, que pueda recuperar lastrayectorias particulares de los distintos flujos migratorios, así como sus necesidadesespecíficas vinculadas al acceso a la salud y a sus prácticas culturales.

PRÁCTICAS RELIGIOSAS EN CONTEXTOS DE MIGRACIÓN. ALGUNAS ARTICULACIONES ENTRE TRANSNACIONALIDAD, LOCALIDAD E IDENTIDADES

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Ana Inés Mallimaci Barral

2016-01-01

Full Text Available En los últimos años el campo de los estudios migratorios se ha visto atravesado por una disputa entre dos perspectivas. Por un lado, el paradigma asimilacionista relacionado con cierto “nacionalismo metodológico”, clásico pero algo arcaico. Por otro lado, la perspectiva transnacional que ha sostenido que los desplazamientos de personas no derivan de manera necesaria en la generación de prácticas de asimilación por parte de los y las migrantes ni tampoco por parte de las sociedades receptoras. Desde la convicción de que los debates conceptuales deben estar encarnados y construidos desde trabajos empíricos, este trabajo propone el análisis de un caso, la festividad religiosa de los y las migrantes bolivianos en Ushuaia, para analizar las tensiones y articulaciones entre lógicas transnacionales y asimilacionistas que atraviesan la vida cotidiana de las poblaciones migrantes.

La chola en el imaginario de la ciudad: decolonialidad y resistencia en Los Andes bolivianos

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Cleverth Carlos Cárdenas Plaza

2018-01-01

Full Text Available El texto expone cómo la chola paceña, por medio de la fiesta popular del Gran Poder, logró revertir los estereotipos negativos que se urdieron acerca de ella. Especialmente, desde principios del siglo XX, cuando se desarrolló todo un discurso destinado a rezagar a su grupo social. Larson (2001, lo llamo el discurso del antimestizaje. Para revertir tales estereotipos, se usó el prestigio de la fraternidad y se mostró su potencial económico, mediante ello se ha reivindicado su lugar en la sociedad. Pero, sobre todo, impuso su vestimenta, su marcador étnico más visible, ante una sociedad que discrimina y racializa.

El léxico del oriente boliviano en el siglo XVIII: una aproximación

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Jose Luis Ramírez-Luengo

2012-07-01

Full Text Available ResumenEste artículo presenta una primera descripción del léxico dieciochesco del español del oriente de Bolivia a partir del "Práctico Diario de Antonio Seoane de los Santos". De su estudio se pueden extraer una serie de conclusiones de cierta relevancia, tales como el empleo ya en esta época de voces propias actualmente de la región, la abundancia de lusismos, o la coincidencia léxica que existe entre esta zona y el área platense.Palabras clave: historia del español de América, léxico, siglo XVIII, Bolivia orientalAbstractThis paper presents a first description of 18th century Eastern Bolivian lexicon, based on Seoane de los Santos’ "Práctico Diario". It is possible to obtain some relevant conclusions from this study, such as the use of some bolivianisms already in this moment, the abundance of Portuguese words, or the lexical coincidence of this region with the Platense area.Keywords: history of American Spanish, vocabulary, 18th century, Eastern Bolivia

Tromboembolismo pulmonar y enfermedad cerebrovascular isquémica embólica en un anciano boliviano

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Daymarelis Rodríguez Yero

2014-06-01

Full Text Available Se describe el caso clínico de un paciente de 71 años de edad, quien en el 2008, luego de un episodio de tromboembolismo pulmonar, fuera ingresado en la Unidad de Cuidados Intensivos del Hospital Integral Comunitario de Chacaltaya en Bolivia, por presentar una enfermedad cerebrovascular isquémica embólica de tipo paradójica, como consecuencia de un agujero oval permeable. Como tratamiento se indicó, primero, heparina de bajo peso molecular y, posteriormente, dicumarínicos, con lo cual el paciente evolucionó satisfactoriamente

El simbolismo del piojo en el mundo andino. Boceto filológico

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Marie-France Souffez

1985-12-01

Full Text Available El valor que se da al piojo varía  según los lugares y las culturas del mundo. En las zonas urbanas peruanas es  sinónimo de  suciedad y  pobreza. En las zonas rurales tradicionales andinas, nos parece estar asociado a la pobreza y a la riqueza, a la muerte y a la vida. Las modalidades-y los matices de expresión de estas asociaciones forman el objeto de nuestro estudio. El presente artículo desarrolla un análisis parcial del vocabulario quechua y aimara relacionado con este parásito.

Recuperación estructural en bosques sucesionales andinos de Porce (Antioquia, Colombia

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Adriana P Yepes

2010-03-01

Full Text Available Lugares susceptibles a perturbaciones naturales o antrópicas pueden recuperar la cobertura boscosa. La sucesión tropical puede ser afectada por factores tales como perturbaciones, distancia al bosque original, topografía y clima local. Estos factores determinan la composición de especies y la tasa de recuperación de los sitios. Se estudió la sucesión en suelos que habían sido usados para el establecimiento de pasturas ganaderas por varias décadas en la Región Porce de Colombia (bosques Colombianos de los Andes. Se midieron un total de veinticinco parcelas, incluyendo nueve parcelas (20x50m en bosques primarios y dieciséis (20x25m en bosques secundarios. Se midieron todos los árboles con un diámetro ≥1.0cm. Se analizó la densidad, área basal, biomasa aérea y riqueza de especies, en un bosque con un proceso sucesional de ca. 43 años y en un bosque primario. Las edades de los bosques secundarios fueron obtenidas en estudios previos usando la datación con carbono catorce (C14, fotografías aéreas y el análisis de imágenes de satélite de alta resolución (entre 7 y >43 años. En total, 1 143 y 1 766 individuos se midieron en bosque primario y secundario, respectivamente. El área basal (5.7 a 85.4m²ha-1, la biomasa aérea (19.1 a 1 011.5 t ha-1 y la riqueza de especies (4 a 69 aumentaron directamente con la edad de los sitios, mientras que la densidad de árboles disminuyó (3 180 a 590. Las distribuciones diamétricas fueron en J-invertida para los bosques primarios y unimodal para los secundarios. Tres especies de palmas fueron abundantes y exclusivas de bosques secundarios viejos y bosques primarios: Oenocarpus mapora, Euterpe precatoria y Oenocarpus bataua. Cohortes de estas palmas aparecieron después de perturbaciones del bosque. La recuperación de la estructura de los bosques secundarios en más de 43 años de sucesión fue 40% e indica que varios factores están interactuando y afectando la sucesión de los bosques en el área (e.g. agricultura, ganadería extensiva, minería, etc..Structural recovering in Andean successional forests from Porce (Antioquia, Colombia. Places subjected to natural or human disturbance can recover forest through an ecological process called secondary succession. Tropical succession is affected by factors such as disturbances, distance from original forest, surface configuration and local climate. These factors determine the composition of species and the time trend of the succession itself. We studied succession in soils used for cattle ranching over various decades in the Porce Region of Colombia (Andean Colombian forests. A set of twenty five permanent plots was measured, including nine plots (20x50m in primary forests and sixteen (20x25m in secondary forests. All trees with diameter ≥1.0cm were measured. We analyzed stem density, basal area, above-ground biomass and species richness, in a successional process of ca. 43 years, and in primary forests. The secondary forests’ age was estimated in previous studies, using radiocarbon dating, aerial photographs and a high-resolution satellite image analysis (7 to >43 years. In total, 1 143 and 1 766 stems were measured in primary and secondary forests, respectively. Basal area (5.7 to 85.4m²ha-1, above-ground biomass (19.1 to 1 011.5 t ha-1 and species richness (4 to 69 directly increased with site age, while steam density decreased (3 180 to 590. Diametric distributions were "J-inverted" for primary forests and even-aged size-class structures for secondary forests. Three species of palms were abundant and exclusive in old secondary forests and primary forests: Oenocarpus mapora, Euterpe precatoria and Oenocarpus bataua. These palms happened in cohorts after forest disturbances. Secondary forest structure was 40% in more than 43 years of forest succession and indicate that many factors are interacting and affecting the forests succession in the area (e.g. agriculture, cattle ranching, mining, etc.. Rev. Biol. Trop. 58 (1: 427-445. Epub 2010 March 01.

La mitigación de heladas en los camellones del altiplano andino

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2003-01-01

Full Text Available The raised fields system is an old technique of soil and water management, which was very frequent in the Lake Titicaca region before the Spanish conquest. It essentially consists of a series of earth platforms surrounded by water canals. Crops are grown on the platforms and water level in the canals is controled through inlet and outlet ditches. An important and widely recognized benefit of this system of management is its contribution to frost mitigation during the growing season. An experiment has been conducted on a system of raised fields in the Lake Titicaca region with the goal of quantifying the phenomenon and specifying the physical processes responsible for the mitigation effect. A potato crop was grown on the platforms of the raised fields and the same crop was grown on a control plot in the “Pampa”. Experimental results show that during the night: (i water temperature is much greater than the temperature of the crop on the platforms (ii crop temperature is always greater (1-2 degrees on the platforms than on the control plot in the Pampa. A physical process-based model, adapted from a two-layer transfer scheme of the Shuttleworth-Wallace type (a vegetation layer and a substrate layer of water, is presented to explain the mitigation effect. The model specifies the role played by the canals in the nocturnal heat dynamics and the night-time variation of crop temperature. The mitigation effect is due to heat emanating from the canals and to water condensation on the leaves. When used in a predictive way, the model shows that wider canals and narrower platforms have a positive impact on the minimum crop temperature reached during the night. Increasing water depth also improves frost mitigation, but conversely, a deeper canal (with the same level of water has a negative impact. Leaf area index (LAI and crop height, both have a positive impact on frost mitigation. The marginal benefit, however, is very small when LAI is greater than 1. Higher wind velocity or higher air relative humidity also enhances the frost mitigation effect. El sistema de camellones o “waru warus” es una antigua técnica agrícola de manejo del suelo y del agua. En los tiempos prehispánicos era muy frecuente en la región del lago Titicaca. Consiste esencialmente en una serie de plataformas de tierra rodeadas por canales de agua. Las plantas se cultivan sobre las plataformas y el nivel del agua en los canales puede controlarse a través de entradas y salidas de agua. Un beneficio importante y ampliamente reconocido de este sistema de manejo en el altiplano es su contribución a la mitigación de heladas nocturnas durante la campaña agrícola. Con el objetivo de cuantificar este fenómeno y describir los procesos físicos responsables de la mitigación, se ha realizado un experimento en la región del lago Titicaca sobre un sistema de camellones cultivado con papas comparándolo con una parcela “testigo” en la “Pampa”. Se presentan resultados experimentales que evidencian por una parte, el valor elevado de la temperatura del agua con respecto a la del cultivo sobre las plataformas, y por otra, una temperatura de cultivo siempre mayor (1-2 grados en los camellones que en la Pampa. Conjuntamente se presenta un modelo mecanístico adaptado de un esquema de transferencia bi-capa de tipo “Shuttleworth-Wallace” (una capa de vegetación y un sustrato de agua. El modelo precisa el papel que juegan los canales en la dinámica del calor y por lo tanto en la variación de la temperatura del cultivo durante la noche. El efecto de mitigación se debe al flujo de calor que emana del agua y a menudo también a la condensación del vapor de agua sobre las hojas del cultivo. Utilizando el modelo de manera predictiva, se muestra que canales más anchos o plataformas más estrechas tienen un impacto positivo sobre la temperatura mínima del cultivo alcanzada durante la noche. Aumentar la profundidad del agua mejora también la mitigación de heladas, pero a la inversa, un canal más profundo (con el mismo nivel de agua tiene un impacto negativo. Aumentar el índice de ��rea foliar (LAI o la altura del cultivo tiene un efecto positivo sobre la mitigación de heladas (el beneficio marginal, sin embargo, es muy pequeño cuando el índice foliar supera el valor 1. Mayor velocidad de viento o mayor humedad relativa incrementa también el efecto de mitigación de heladas. Le système des ados ou waru warus, est une ancienne technique agricole qui était très fréquente dans la région du lac Titicaca à l’époque préhispanique. Elle consiste essentiellement en une série de plateformes de terre surélevées entourées par des canaux. Les plantes se cultivent sur les plateformes et le niveau d’eau dans les canaux est contrôlé par les entrées et sorties. Un bénéfice important et largement reconnu de ce système de culture sur l’altiplano est sa contribution à l’atténuation des gelées nocturnes durant la campagne agricole. Dans le but de quantifier ce phénomène et de décrire les processus physiques responsables de cette atténuation une expérimentation a été conduite dans la région du lac Titicaca en comparant un système d’ados cultivés avec des pommes de terre avec une parcelle témoin dans la “ Pampa ”. Les résultats expérimentaux mettent en évidence, d’une part la valeur élevée de la température de l’eau par rapport à celle de la culture sur les plateformes, d’autre part une température de la culture toujours plus élevée (1-2 degrés dans les ados que dans la Pampa. On présente également un modèle mécaniste, adapté d’un schéma de transfert bi-couche de type “ Shuttleworth-Wallace ” (une couche représentant la végétation et une couche représentant le substrat d’eau. Le modèle précise le rôle joué la nuit par les canaux dans la dynamique de la chaleur et dans la variation de la température de la culture. Il apparaît que l’effet d’atténuation est dû principalement au flux de chaleur sensible qui émane de l’eau, mais souvent aussi à la condensation de vapeur d’eau sur les feuilles de la culture. En utilisant le modèle de manière prédictive on montre que des canaux plus larges ou des plateformes plus étroites ont un impact positif sur la température minimale de la culture atteinte durant la nuit. Augmenter la profondeur de l’eau améliore également l’effet d’atténuation des gelées, mais à l’inverse, un canal plus profond, avec le même niveau d’eau, a un impact négatif. L’augmentation de la surface foliaire (LAI ou de la hauteur du couvert a un effet positif sur l’atténuation des gelées. Une vitesse de vent plus forte ou une humidité relative de l’air plus élevée accroît également l’effet d’atténuation.

Relative influence of human harvest, carnivores, and weather on adult female elk survival across western North America

Science.gov (United States)

Brodie, Jedediah; Johnson, Heather; Mitchell, Michael; Zager, Peter; Proffitt, Kelly; Hebblewhite, Mark; Kauffman, Matthew; Johnson, Bruce; Bissonette, John; Bishop, Chad; Gude, Justin; Herbert, Jeff; Hersey, Kent R.; Hurley, Mark; Lukacs, Paul M.; McCorquodale, Scott; McIntire, Eliot; Nowak, Josh; Sawyer, Hall; Smith, Douglas; White, P.J.

2013-01-01

Well-informed management of harvested species requires understanding how changing ecological conditions affect demography and population dynamics, information that is lacking for many species. We have limited understanding of the relative influence of carnivores, harvest, weather and forage availability on elk Cervus elaphus demography, despite the ecological and economic importance of this species. We assessed adult female survival, a key vital rate for population dynamics, from 2746 radio-collared elk in 45 populations across western North America that experience wide variation in carnivore assemblage, harvest, weather and habitat conditions. Proportional hazard analysis revealed that 'baseline' (i.e. not related to human factors) mortality was higher with very high winter precipitation, particularly in populations sympatric with wolves Canis lupus. Mortality may increase via nutritional stress and heightened vulnerability to predation in snowy winters. Baseline mortality was unrelated to puma Puma concolor presence, forest cover or summer forage productivity. Cause-specific mortality analyses showed that wolves and all carnivore species combined had additive effects on baseline elk mortality, but only reduced survival by <2%. When human factors were included, ‘total’ adult mortality was solely related to harvest; the influence of native carnivores was compensatory. Annual total mortality rates were lowest in populations sympatric with both pumas and wolves because managers reduced female harvest in areas with abundant or diverse carnivores. Mortality from native carnivores peaked in late winter and early spring, while harvest-induced mortality peaked in autumn. The strong peak in harvest-induced mortality during the autumn hunting season decreased as the number of native carnivore species increased. Synthesis and applications. Elevated baseline adult female elk mortality from wolves in years with high winter precipitation could affect elk abundance as

Pumas affect elk dynamics in absence of other large carnivores

Science.gov (United States)

Chadwick P. Lehman; Christopher T. Rota; Jarod D. Raithel; Joshua J. Millspaugh

2017-01-01

We investigated survival, reproduction, and population growth (λ) for a declining elk (Cervus canadensis nelsoni) population in South Dakota, USA, 2011-2015. We obtained survival data from 125 calves and 34 yearlings. We determined survival and pregnancy rates for 42 adults (2-8 years old) and 39 old adults (≥8 years old). We combined population vital rates into a...

Non-volant mammals in a protected area on the Central Andes of Colombia: new records for the Caldas department and the Chinchiná River basin

OpenAIRE

Ramírez-Mejía, Andrés; Sánchez, Francisco

2015-01-01

The Chinchiná River basin is located on the western slope of the Colombian Central Andes. This basin provides ecosystem services such as water provision for >500,000 people, but has suffered considerable ecosystem degradation, and the information on its biodiversity is limited. We inventoried the non-volant mammals in the Caldas' Central Hydroelectric (CHEC) Reserve in the Chinchiná River basin, in the Caldas department. We detected 18 species of mammals, present the first record of Puma ya...

Courant Mathematics and Computing Laboratory, New York University. Progress report No. 54, October 1, 1977--September 30, 1978

International Nuclear Information System (INIS)

1978-01-01

Work is reported in the following areas: applied mathematics (computational fluid dynamics, numerical analysis), computational magnetohydrodynamics, computational physics and chemistry (materials science, quantum many-body systems, chemistry), computer science (CIMS PL/I, Version II; distributed systems and resource sharing, computer design - PUMA; SETL; algorithmic combinatorics), systems programing and user services. The relationship to other projects, list of seminars, and list of publications are also included. The research descriptions are administrative in nature, usually less than a page in length

Mountain lions prey selectively on prion-infected mule deer

OpenAIRE

Krumm, Caroline E.; Conner, Mary M.; Hobbs, N. Thompson; Hunter, Don O.; Miller, Michael W.

2009-01-01

The possibility that predators choose prey selectively based on age or condition has been suggested but rarely tested. We examined whether mountain lions (Puma concolor) selectively prey upon mule deer (Odocoileus hemionus) infected with chronic wasting disease, a prion disease. We located kill sites of mountain lions in the northern Front Range of Colorado, USA, and compared disease prevalence among lion-killed adult (?2 years old) deer with prevalence among sympatric deer taken by hunters i...

Neutron scattering. Experiment manuals

International Nuclear Information System (INIS)

Brueckel, Thomas; Heger, Gernot; Richter, Dieter; Roth, Georg; Zorn, Reiner

2014-01-01

The following topics are dealt with: The thermal triple-axis spectrometer PUMA, the high-resolution powder diffractometer SPODI, the hot-single-crystal diffractometer HEiDi, the three-axis spectrometer PANDA, the backscattering spectrometer SPHERES, the DNS neutron-polarization analysis, the neutron spin-echo spectrometer J-NSE, small-angle neutron scattering at KWS-1 and KWS-2, a very-small-angle neutron scattering diffractometer with focusing mirror, the reflectometer TREFF, the time-of-flight spectrometer TOFTOF. (HSI)

Toward a Panther-centered View of the Forests of South Florida

OpenAIRE

Andrew J. Kerkhoff; Bruce T. Milne; David S. Maehr

2000-01-01

Anthropogenic habitat degradation and loss is the single largest threat to the endangered Florida panther, Puma concolor coryi. Conservation of the subspecies must be undertaken on the scale of the entire landscape. Thus, a view of the forested landscape of South Florida must be developed that is meaningful with reference to the panther. We approach this problem by analyzing the spatial interactions of panthers and forests at multiple scales. We apply tools derived from fractal geometry to th...

Operation of Atucha I nuclear power plant with 25 cooling channels without fuel elements

International Nuclear Information System (INIS)

Perez, R.A.; Sidelnik, J.I.; Salom, G.F.

1987-01-01

In view of the need of removing the irradiation probes from the reactor of Atucha I nuclear power plant, a study about the consequences of operating with 25 channels without their respective fuel elements was performed. This condition was simulated by means of the code PUMA symmetry I and the consequences were analyzed. From the study resulted a program of stepped power reduction of the nuclear plant that would take place during the process of channel emptying. (Author)

Shawarmas contra Macdonald’s. Shawarmas contra Mcdonald’s. Globalização e homogeneização à prova de contestações identitárias (Bolívia Shawarmas versus Macdonald’s. Identities contesting food globalization and standardization (Bolivia

Directory of Open Access Journals (Sweden)

Charles-Édouard de Suremain

2009-12-01

Full Text Available En este artículo, a partir de la alimentación, se aborda las interrogantes de las identidades locales y de su articulación a la globalización y a la estandarización. Después de haber presentado los lugares donde es posible comer fuera de casa en La Paz, me detendré en las particularidades del McDonald boliviano. Estos datos permitirán seguir la génesis de un antimodelo alimentario, el shawarma, el cual conoció su apogeo durante “la Tercera Guerra Mundial”, el periodo iniciado con el paso de los atentados del 11 de septiembre de 2001. La hipótesis es que las protestas identitarias en la esfera alimenticia pueden apoyarse en la lógica de la globalización alimentaria y erigirse contra ella, evitando los embrollos de la estandarización alimentaria.Neste artigo, sob a perspectiva da alimentação, será abordada as questões de identidades locais e sua articulação à globalização e homogeneização. Após descrever os espaços do comer fora de casa na cidade de La Paz, Bolívia, o artigo irá explorar as particularidades do caso do McDonald’s boliviano. Esses dados permitirão seguir a gênese de um anti-modelo alimentar, o shawarma, que conheceu seu apogeu ao longo da “3ª Guerra mundial”, período iniciado em seguida aos atentados do 11 de setembro de 2001. A hipótese é que as contestações identitarias da esfera alimentar podem se apoiar na lógica da globalização e constituir-se contra ela, evitando as armadilhas da homogeneização.Local identities and their tendency toward globalization and standardization is analyzed here with food as an example. After briefly reviewing the different places where one can eat out in La Paz, the particularities of the Bolivian McDonald’s are outlined. These data allow us to witness the birth of a food anti-model, the shawarma, which reached its pinnacle during the so-called ‘Third World War’, the period following September 11, 2001. The hypothesis is that identity

Exposure of Free-Ranging Wild Carnivores and Domestic Dogs to Canine Distemper Virus and Parvovirus in the Cerrado of Central Brazil.

Science.gov (United States)

Furtado, Mariana Malzoni; Hayashi, Erika Midori Kida; Allendorf, Susan Dora; Coelho, Claudio José; de Almeida Jácomo, Anah Tereza; Megid, Jane; Ramos Filho, José Domingues; Silveira, Leandro; Tôrres, Natália Mundim; Ferreira Neto, José Soares

2016-09-01

Human population growth around protected areas increases the contact between wild and domestic animals, promoting disease transmission between them. This study investigates the exposure of free-ranging wild carnivores and domestic dogs to canine distemper virus (CDV) and parvovirus in Emas National Park (ENP) in the Cerrado savanna of central Brazil. Serum samples were collected from 169 wild carnivores, including the maned wolf (Chrysocyon brachyurus), crab-eating fox (Cerdocyon thous), hoary fox (Pseudalopex vetulus), puma (Puma concolor), ocelot (Leopardus pardalis), pampas cat (Leopardus colocolo), jaguarundi (Herpailurus yagouaroundi), striped hog-nosed skunk (Conepatus semistriatus) and coati (Nasua nasua), and from 35 domestic dogs living on rural properties bordering ENP. Serological tests showed that 10.6% of wild carnivores (maned wolves, crab-eating foxes and ocelots) and 71.4% of domestic dogs were exposed to CDV, and 56.8% of wild carnivores, including all species sampled except coatis, and 57.1% of domestic dogs were exposed to parvovirus. This report is the first to indicate that the free-ranging pampas cat, jaguarundi and striped hog-nosed skunk are exposed to parvovirus. CDV and parvovirus deserve attention in ENP, and it is extremely important to monitor the health of carnivore populations and perform molecular diagnosis of the viruses to determine the possible involvement of the domestic dog in their transmission.

Genetic introgression and the survival of Florida panther kittens

Science.gov (United States)

Hostetler, Jeffrey A.; Onorato, David P.; Nichols, James D.; Johnson, Warren E.; Roelke, Melody E.; O'Brien, Stephen J.; Jansen, Deborah; Oli, Madan K.

2010-01-01

Estimates of survival for the young of a species are critical for population models. These models can often be improved by determining the effects of management actions and population abundance on this demographic parameter. We used multiple sources of data collected during 1982–2008 and a live-recapture dead-recovery modeling framework to estimate and model survival of Florida panther (Puma concolor coryi) kittens (age 0–1 year). Overall, annual survival of Florida panther kittens was 0.323 ± 0.071 (SE), which was lower than estimates used in previous population models. In 1995, female pumas from Texas (P. c. stanleyana) were released into occupied panther range as part of an intentional introgression program to restore genetic variability. We found that kitten survival generally increased with degree of admixture: F1 admixed and backcrossed to Texas kittens survived better than canonical Florida panther and backcrossed to canonical kittens. Average heterozygosity positively influenced kitten and older panther survival, whereas index of panther abundance negatively influenced kitten survival. Our results provide strong evidence for the positive population-level impact of genetic introgression on Florida panthers. Our approach to integrate data from multiple sources was effective at improving robustness as well as precision of estimates of Florida panther kitten survival, and can be useful in estimating vital rates for other elusive species with sparse data.

Lavalleja group (Uruguay), a neoproterozoic metavolcanic-metasedimentary sequence:geochemistry and geochronological features

International Nuclear Information System (INIS)

Preciozzi, F.; Sanchez Bettucci, L.; Basei, M.

2003-01-01

The Lavalleja Group is located in the southern portion of the Dom Feliciano Belt, being correlated with the Porongos and Brusque Groups in Brazil. This Group has a granitic-gneissic basement probably associated to the Valentines Block and Pavas Terrane, with ages ranging from 1.75 to 2.1 Ga (U-Pb determination). An older basement probably occurs. This Group is characterized by narrow bands of metasedimentary and metavolcanic rocks and is subdivided into three formations (Sánchez-Bettucci, 1998). The first one includes lithologies with a very low to anquimetamorphism degree; the second one is formed by rocks with low metamorphism degree (lower greenschist facies) and the last one presents an upper greenschist facies in transition to upper and lower amphibolite facies. They correspond respectively to the Minas, Fuente del Puma and Zanja del Tigre Formations. The Minas Formation includes only metasedimentary rocks: limestones, dolomites, metapelites, quartzites and arkoses. The Fuente del Puma Formation is formed by three units (Sanchez-Bettucci, 1998): the sedimentary, volcanic and hornblenditic gabbros units. The Zanja del Tigre Formation shows lithologies of medium metamorphism degree, developed to the east of the two other Formations. Syn-collisional to postectonic granitic bodies are associated to the Lavalleja Group. These granitic bodies correspond to the Carapé Complex. The paleoproterozoic basement of Lavalleja Group and Carapé Complex is named Campanero Unit

Cross transmission of gastrointestinal nematodes between captive neotropical felids and feral cats.

Science.gov (United States)

Rendón-Franco, Emilio; Romero-Callejas, Evangelina; Villanueva-García, Claudia; Osorio-Sarabia, David; Muñoz-García, Claudia I

2013-12-01

Pathogen cross transmission between wildlife and domestic animals represents an extinction risk for wildlife; however, reliable verification is difficult to perform, and in some cases, it is even considered unlikely to be conducted. The aim of this work was to identify cross transmission of helminths between feral cats and captive wild felids at a zoological park in southeastern Mexico. Feces were collected from jaguars (Panthera onca), cougars (Puma concolor), ocelots (Leopardus pardalis), margays (Leopardus wiedii), and jaguarundis (Puma yagouaroundi). A flotation technique and macroscopic sieving were performed on the feces. Additionally, as part of the noxious fauna control program of the park, feral cats were captured and euthanized. To perform parasitologic studies, helminths from these animals were recovered. Toxocara cati and Trichuris campanula were shared by jaguarundis and feral cats. Ancylostoma sp. was found in jaguar and ocelot and Ancylostoma tubaeforme in feral cats. Additionally, during this study, a couple of jaguarundis died with clinical signs of trichuriasis. This is the first report of T. campanula in jaguarundi. Because feral cats roam freely in the park, transmission could occur from these vertebrates to wild felids. This study shows the risk that parasites represent to wild felids; a similar situation could be found in free-living species, especially in fragmented habitats that favor contact with domestic animals.