Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus.

Science.gov (United States)

Suzuki, Masako; Maekawa, Ryo; Patterson, Nicole E; Reynolds, David M; Calder, Brent R; Reznik, Sandra E; Heo, Hye J; Einstein, Francine Hughes; Greally, John M

2016-01-01

Preeclampsia, traditionally characterized by high blood pressure and proteinuria, is a common pregnancy complication, which affects 2-8 % of all pregnancies. Although children born to women with preeclampsia have a higher risk of hypertension in later life, the mechanism of this increased risk is unknown. DNA methylation is an epigenetic modification that has been studied as a mediator of cellular memory of adverse exposures in utero. Since each cell type in the body has a unique DNA profile, cell subtype composition is a major confounding factor in studies of tissues with heterogeneous cell types. The best way to avoid this confounding effect is by using purified cell types. However, using purified cell types in large cohort translational studies is difficult. The amnion, the inner layer of the fetal membranes of the placenta, is derived from the epiblast and consists of two cell types, which are easy to isolate from the delivered placenta. In this study, we demonstrate the value of using amnion samples for DNA methylation studies, revealing distinctive patterns between fetuses exposed to proteinuria or hypertension and fetuses from normal pregnancies. We performed a genome-wide DNA methylation analysis, HpaII tiny fragment Enrichment by Ligation-mediated PCR (HELP)-tagging, on 62 amnion samples from the placentas of uncomplicated, normal pregnancies and from those with complications of preeclampsia or hypertension. Using a regression model approach, we found 123, 85, and 99 loci with high-confidence hypertension-associated, proteinuria-associated, and hypertension- and proteinuria-associated DNA methylation changes, respectively. A gene ontology analysis showed DNA methylation changes to be selecting genes with different biological processes in exposure status. We also found that these differentially methylated regions overlap loci previously reported as differentially methylated regions in preeclampsia. Our findings support prior observations that preeclampsia

Regenerative and Antibacterial Properties of Acellular Fish Skin Grafts and Human Amnion/Chorion Membrane: Implications for Tissue Preservation in Combat Casualty Care.

Science.gov (United States)

Magnusson, Skuli; Baldursson, Baldur Tumi; Kjartansson, Hilmar; Rolfsson, Ottar; Sigurjonsson, Gudmundur Fertram

2017-03-01

Improvised explosive devices and new directed energy weapons are changing warfare injuries from penetrating wounds to large surface area thermal and blast injuries. Acellular fish skin is used for tissue repair and during manufacturing subjected to gentle processing compared to biologic materials derived from mammals. This is due to the absence of viral and prion disease transmission risk, preserving natural structure and composition of the fish skin graft. The aim of this study was to assess properties of acellular fish skin relevant for severe battlefield injuries and to compare those properties with those of dehydrated human amnion/chorion membrane. We evaluated cell ingrowth capabilities of the biological materials with microscopy techniques. Bacterial barrier properties were tested with a 2-chamber model. The microstructure of the acellular fish skin is highly porous, whereas the microstructure of dehydrated human amnion/chorion membrane is mostly nonporous. The fish skin grafts show superior ability to support 3-dimensional ingrowth of cells compared to dehydrated human amnion/chorion membrane (p fish skin is a bacterial barrier for 24 to 48 hours. The unique biomechanical properties of the acellular fish skin graft make it ideal to be used as a conformal cover for severe trauma and burn wounds in the battlefield. Reprint & Copyright © 2017 Association of Military Surgeons of the U.S.

Amnion and Chorion Membranes: Potential Stem Cell Reservoir with Wide Applications in Periodontics.

Science.gov (United States)

Gupta, Akanksha; Kedige, Suresh D; Jain, Kanu

2015-01-01

The periodontal therapy usually aims at elimination of disease causing bacteria and resolution of inflammation. It involves either resective or regenerative surgery to resolve the inflammation associated defects. Over the years, several methods have been used for achievement of periodontal regeneration. One of the oldest biomaterials used for scaffolds is the fetal membrane. The amniotic membranes of developing embryo, that is, amnion (innermost lining) and chorion (a layer next to it), have the properties with significant potential uses in dentistry. This paper reviews the properties, mechanism of action, and various applications of these placental membranes in general and specifically in Periodontics.

Influence of physiologically active complex isolated from human amnion on lipid peroxide oxidation state and antioxidant activity of blood in rats after irradiation in different doses

International Nuclear Information System (INIS)

Borshchevs'ka, M.Yi.; Popov, V.V.; Abramova, L.P.; Kuz'myinova, Yi.A.

1995-01-01

The authors have studied the influence of physiologically active complex isolated from human amnion on the state of lipid peroxide oxidation according to diene conjugate and malonic dialdehyde amount and antioxidant enzyme activity (catalase and glutationperoxidase) in the blood of the rats exposed to single total irradiation in different doses (4 and 6 Gy) was studied. Definite changes of peroxide process intensity and reduction of the enzymes activity were shown to be observed in the blood of experimental animals even at long terms after the radiation exposure. Under the background of radiation exposure, administration of physiologically active complex isolated from human amnion produced protective effect on antioxidant enzyme activity which promoted normalization of peroxidation processes within the post-radiation period

Amnioinfusion in preterm PROM: effects on amnion and cord histology.

Science.gov (United States)

Locatelli, A; Andreani, M; Ghidini, A; Verderio, M; Pizzardi, A; Vergani, P; Salafia, C M

2008-02-01

To investigate the effects of transabdominal amnioinfusion (TA) on the histology of amnion (A) and umbilical cord (UC). From a cohort of 56 singleton pregnancies with premature rupture of membranes (PROM) at

Pregnancy outcome of monochorionic twins: does amnionicity matter?

Science.gov (United States)

Dias, Thiran; Contro, Elena; Thilaganathan, Basky; Khan, Hina; Zanardini, Cristina; Mahsud-Dornan, Samina; Bhide, Amar

2011-12-01

To compare the fetal loss rate of monochorionic (MC) twin pregnancies according to their amnionicity. A retrospective review of all MC pregnancy outcomes in a tertiary centre. Pregnancy outcomes were compared for monochorionic monoamniotic (MCMA) versus monochorionic diamniotic (MCDA) pregnancies. 29 MCMA and 117 MCDA twin pregnancies were identified. The overall fetal loss rate was significantly higher in MCMA (23/52, 44.2%) compared to MCDA pregnancies (28/233, 12%, Chi squared = 30.03, p fetal survival rate in MCDA twins were significantly higher than in MCMA twins (Log-rank Chi-squared = 27.9, p fetal losses in some MCMA twins. After exclusion of identifiable causes, the difference in fetal survival was not significant in the two groups (Log-rank chi-squared = 0.373, p = .54). The loss rate for MCMA twins is high and occurs mainly due to discordant congenital abnormality, conjoint twins or twin reversed arterial perfusion (TRAP) sequence. Although the fetal loss rate in MCDA is lower than in MCMA pregnancies, the majority of fetal loss in MCDA pregnancies cannot be predicted at the first scan at presentation. The data of this study questions the widespread policy of a difference in the scheduling of elective delivery for MCMA and MCDA twins.

Human amnion mesenchymal stem cells promote proliferation and osteogenic differentiation in human bone marrow mesenchymal stem cells.

Science.gov (United States)

Wang, Yuli; Yin, Ying; Jiang, Fei; Chen, Ning

2015-02-01

Human amnion mesenchymal stem cells (HAMSCs) can be obtained from human amniotic membrane, a highly abundant and readily available tissue. HAMSC sources present fewer ethical issues, have low immunogenicity, anti-inflammatory properties, considerable advantageous characteristics, and are considered an attractive potential treatment material in the field of regenerative medicine. We used a co-culture system to determine whether HAMSCs could promote osteogenesis in human bone marrow mesenchymal stem cells (HBMSCs). We isolated HAMSCs from discarded amnion samples and collected them using pancreatin/collagenase digestion. We cultured HAMSCs and HBMSCSs in basal medium. Activity of alkaline phosphatase (ALP), an early osteogenesis marker, was increased in the co-culture system compared to the control single cultures, which we also confirmed by ALP staining. We used immunofluorescence testing to investigate the effects of co-culturing with HAMSCs on HBMSC proliferation, which revealed that the co-culturing enhanced EdU expression in HBMSCs. Western blotting and quantitative real-time PCR indicated that co-culturing promoted osteogenesis in HBMSCs. Furthermore, Alizarin red S staining revealed that extracellular matrix calcium levels in mineralized nodule formation produced by the co-cultures were higher than that in the controls. Using the same co-culture system, we further observed the effects of HAMSCs on osteogenic differentiation in primary osteoblasts by Western blotting, which better addressed the mechanism for HAMSCs in bone regeneration. The results showed HAMSCs are osteogenic and not only play a role in promoting HBMSC proliferation and osteogenic differentiation but also in osteoblasts, laying the foundation for new regenerative medicine methods.

The correlation between histologic placentitis and amnionitis and the amnioniotic fluid's inflammatory cytokines in case of spontaneous pre-term labor with intact membrane

Directory of Open Access Journals (Sweden)

Agus Abadi

2001-12-01

Full Text Available Pre-term labor is presumed to result from spreading of lower genital infection to upper part, subsequently to decidual and choioamniotic tissues. Host response to this injury include the expression of protein which is responsible to the inflammatory reactions. The expression of the inflammatory cytokines such as IL-1β, IL-6, IL-8 and TNF-α increase in case of infection.These cytokines may play an essential role in the pathophysiology of spontaneous pretem labor with intact membrane.An observational analytic cohort study was caried out on cases of spontaneous pre-tefln labor with intact membrane. The objectives of this study are to examine the relationship between l the histologic amnionitis and placentitis and the incidence of preterm delivery,2 the expression of amniotic fluid's IL-1β, IL-6, IL-8 and TNF-α and the incidence of preterm delivery, 3 the level of amniotic fluid's IL-1β, IL-6, IL-8 and TNF-α and the grade of histologic amnionitis and placentitis in case of pre-term labor with intact membrane. Cases of spontaneous Pre'teftn labor with intact membrane which underwent transabdominal amniocentesis at admission and managed as standard procedure for pre-term labor with intact membrane. Atl of the cases were observed until the delivery of the baby, eithir preterm or term. The membrane and the placentawere cut postnatally and then the histologic acute inflammation eyaluated based on the criteria of Salafia.The level of amniotic fluid IL-1β, IL-6, IL-8 and TNF-α were analyzed quantitatively by Elisa method. This study showed thet the degree of histologic amnionitis and placentitis, and the level of amniotic fluid's IL-1β, IL-6, IL-8 and TNF-α were significantly higher in pre-term compared to terrn deliveries (p<0.05 and lhere were a positive correlation between the grade of histoLogic inflammation and the level of amniotic fluid's cytokines (Spearmann Rank Conelation test; p<0,05 in cases of preterm labor with intact membrane. The

Syndecan expressions in the human amnion and chorionic plate

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T. Lorenzi

2010-10-01

Full Text Available The syndecan family consists of four distinct membrane glycoproteins in mammals. Syndecans control cell proliferation, differentiation, adhesion and migration through participation in cell-cell interactions, anchorage of cells to the extracellular environment, and modulation of multiple growth factors. Therefore, syndecans may play a pivotal role in the regulation of cell behaviour depending on the cellular microenvironment. Here, we demonstrate that syndecan-1, syndecan-2 and syndecan-4 are expressed in fetal membrane tissue with different immunolocalizations. Syndecan-1 is expressed in the amniotic epithelium, localizing at basolateral cell surfaces. Syndecan-2 and syndecan-4, in contrast, are mostly localized in intracellular compartments, in the extravillous cytotrophoblastic cells and in some fibroblasts of the chorionic plate as well as in the amniotic epithelial cells. In the latter, syndecan-4 is mainly localized in the apical part of the cells. Our results strongly suggest a key role of syndecan-1, syndecan-2 and syndecan-4 in the determination of structural and functional characteristics of human amnion and chorionic plate. Since the solute exchanges between fetus and mother take place in fetal membranes, our data suggest that syndecans are important players in the placenta for the establishment of the fetal-maternal inter-communication.

Brief communication: sliding displacement of amnion and chorion following controlled laser wounding suggests a mechanism for short-term sealing of ruptured membranes.

Science.gov (United States)

Behzad, F; Dickinson, M R; Charlton, A; Aplin, J D

1994-10-01

The Erbium-YAG laser was used to produce narrow wounds of defined depth in term amniochorion. The charring effect of the laser meant that sites could be readily localized in histological sections. During brief post-wounding incubations, sliding displacement of the amnion relative to the chorion occurred through the plane of the spongy layer. This suggests a possible short-term mechanism whereby a spontaneous rupture could be sealed in vivo.

Amnion s and radio-sterilized porcine skin use as potential matrices for the development of human skin substitutes

International Nuclear Information System (INIS)

Martinez P, M. E.; Reyes F, M. L.; Reboyo B, D.; Velasquillo M, M. C.; Sanchez S, R.; Brena M, A. M.; Ibarra P, J. C.

2014-10-01

The injuries by burns constitute a primordial problem of public health; they cause a high mortality index, severe physical and psychological disability, etc. The autologous skin transplant is the replacement therapy recommended for its treatment, but in patients that present a high percentage of burnt skin; this is not possible to carry out. Another strategy is the transplant of donated skin; however, due to the little donation that exists in our country is not very feasible to apply this treatment. A challenge of the tissues engineering is to develop biological skin substitutes, based on cells and amnion s, favoring the cutaneous regeneration and quick repair of injuries, diminishing this way the hospitalization expenses. At present skin substitutes that can equal to the same skin do not exist. On the other hand, the mesenchymal stromal cells (Msc) represent an alternative to achieve this objective; since has been demonstrated that the Msc participate in the tissue repair by means of inhibition of pro-inflammatory cytokines and differentiation to dermal fibroblasts and keratinocytes. To apply the Msc in cutaneous injuries a support material is required that to allow transplanting these cells to a lesion or burn. The radio-sterilized human amnion and the radio-sterilized porcine skin, processed by the Radio-Sterilized Tissues Bank of the Instituto Nacional de Investigaciones Nucleares (ININ), are biomaterials that are used as temporary cutaneous coverings. We suppose that these two matrices will be appropriate for the growth and maintenance in cultivation of the Msc, to generate two biological skin substitutes, in collaboration with the Biotechnology Laboratory of the Instituto Nacional de Rehabilitacion. (Author)

Marine Radioecology. Current Research and Future Scope

International Nuclear Information System (INIS)

1967-03-01

This report consists of answers submitted by various laboratory directors or individual investigators who responded to an International Atomic Energy Agency questionnaire concerning their present research programme, future scope of that programme, the investigators' ideas and opinions on marine radioecology research. Information on the possibility of co-operation with other laboratories is also included

Comparison of the effects of taurine and magnesium on electrical characteristics of artificial and natural membranes. V. Study on the human amnion of the antagonism between magnesium, taurine and polluting metals

Energy Technology Data Exchange (ETDEWEB)

Bara, M.; Guiet-Bara, A.; Durlach, J.

1985-01-01

The effects of metal pollutants (Pb, Cd, Hg, As) were studied on strips of human amnion isolated from the placental zone put in between two Ussing chambers with Hanks' solution at 37 degrees C and pH 7.4. The total conductance Gt through the human isolated amnion was decreased on the fetal side by Pb and As; on the maternal side by Cd, Hg and As. When Gt was decreased by metal pollutants, Mg or taurine (TA) were added in the external medium to induce an antagonism between Mg or TA and metal pollutants. The addition of Mg increased significantly the Gt reduced by Pb, Cd and Hg, but had no effect on the Gt reduced by As. The addition of taurine increased significantly the Gt reduced by Cd and Hg, but had no effect on the Gt reduced by Pb and As. Dixon's kinetics (Gt as a function of the Mg or TA concentration when the metal pollutant concentration increased) indicate that there is a competitive inhibition between Mg-Pb and Mg-Cd (the inhibition constant Ki is lower with Pb (= 2.5) than with Cd (= 11.4) and suggests a greater antagonism between Mg-Pb than between Mg-Cd). Moreover, there appears to be a noncompetitive inhibition between Mg-Hg, TA-Cd and TA-Hg. These results indicate that Mg and TA, on the fetal side, exert an action on the same sites and that, on the maternal side, their action takes place on the same sites and also on different ones. Also, TA can be considered as a partial magnesium agonist, at least in the human amnion.

ASME nuclear codes and standards: Scope of coverage and current initiatives

International Nuclear Information System (INIS)

Eisenberg, G. M.

1995-01-01

The objective of this paper is to address the broad scope of coverage of nuclear codes, standards and guides produced and administered by the American Society of Mechanical Engineers (ASME). Background information is provided regarding the evolution of the present activities. Details are provided on current initiatives intended to permit ASME to meet the needs of a changing nuclear industry on a worldwide scale. During the early years of commercial nuclear power, ASME produced a code for the construction of nuclear vessels used in the reactor coolant pressure boundary, containment and auxiliary systems. In response to industry growth, ASME Code coverage soon broadened to include rules for construction of other nuclear components, and inservice inspection of nuclear reactor coolant systems. In the years following this, the scope of ASME nuclear codes, standards and guides has been broadened significantly to include air cleaning activities for nuclear power reactors, operation and maintenance of nuclear power plants, quality assurance programs, cranes for nuclear facilities, qualification of mechanical equipment, and concrete reactor vessels and containments. ASME focuses on globalization of its codes, standards and guides by encouraging and promoting their use in the international community and by actively seeking participation of international members on its technical and supervisory committees and in accreditation activities. Details are provided on current international representation. Initiatives are underway to separate the technical requirements from administrative and enforcement requirements, to convert to hard metric units, to provide for non-U. S. materials, and to provide for translations into non-English languages. ASME activity as an accredited ISO 9000 registrar for suppliers of mechanical equipment is described. Rules are being developed for construction of containment systems for nuclear spent fuel and high-level waste transport packagings. Intensive

Biological wound dressings sterilized with gamma radiation: Mexican clinical experience

Science.gov (United States)

Martínez-Pardo, M. E.; Ley-Chávez, E.; Reyes-Frías, M. L.; Rodríguez-Ferreyra, P.; Vázquez-Maya, L.; Salazar, M. A.

2007-11-01

Biological wound dressings sterilized with gamma radiation, such as amnion and pig skin, are a reality in Mexico. These tissues are currently processed in the tissue bank and sterilized in the Gamma Industrial Irradiation Plant; both facilities belong to the Instituto Nacional de Investigaciones Nucleares (ININ) (National Institute of Nuclear Research). With the strong support of the International Atomic Energy Agency, the bank was established at the ININ and the Mexican Ministry of Health issued its sanitary license on July 7, 1999. The Quality Management System of the bank was certified by ISO 9001:2000 on August 1, 2003; the scope of the system is "Research, Development and Processing of Biological Tissues Sterilized with Gamma Radiation". At present, more than 150 patients from 16 hospitals have been successfully treated with these tissues. This paper presents a brief description of the tissue processing, as well as the present Mexican clinical experience with children and adult patients who underwent medical treatment with radiosterilized amnion and pig skin, used as biological wound dressings on burns and ocular surface disorders.

Biological wound dressings sterilized with gamma radiation: Mexican clinical experience

Energy Technology Data Exchange (ETDEWEB)

Martinez-Pardo, M.E. [Instituto Nacional de Investigaciones Nucleares, Apdo. postal 18-1027, Col. Escandon 11801 Mexico DF (Mexico)], E-mail: memp@nuclear.inin.mx; Ley-Chavez, E. [ISSEMYM Toluca, Mexico DF (Mexico); Reyes-Frias, M.L. [Instituto Nacional de Investigaciones Nucleares, Apdo. postal 18-1027, Col. Escandon 11801 Mexico DF (Mexico); Rodriguez-Ferreyra, P. [Hospital ' Dr. Nicolas San Juan' , Toluca, Mexico DF (Mexico); Vazquez-Maya, L.; Salazar, M.A. [Hospital General de Mexico, Mexico DF (Mexico)

2007-11-15

Biological wound dressings sterilized with gamma radiation, such as amnion and pig skin, are a reality in Mexico. These tissues are currently processed in the tissue bank and sterilized in the Gamma Industrial Irradiation Plant; both facilities belong to the Instituto Nacional de Investigaciones Nucleares (ININ) (National Institute of Nuclear Research). With the strong support of the International Atomic Energy Agency, the bank was established at the ININ and the Mexican Ministry of Health issued its sanitary license on July 7, 1999. The Quality Management System of the bank was certified by ISO 9001:2000 on August 1, 2003; the scope of the system is 'Research, Development and Processing of Biological Tissues Sterilized with Gamma Radiation'. At present, more than 150 patients from 16 hospitals have been successfully treated with these tissues. This paper presents a brief description of the tissue processing, as well as the present Mexican clinical experience with children and adult patients who underwent medical treatment with radiosterilized amnion and pig skin, used as biological wound dressings on burns and ocular surface disorders.

Biological wound dressings sterilized with gamma radiation: Mexican clinical experience

International Nuclear Information System (INIS)

Martinez-Pardo, M.E.; Ley-Chavez, E.; Reyes-Frias, M.L.; Rodriguez-Ferreyra, P.; Vazquez-Maya, L.; Salazar, M.A.

2007-01-01

Biological wound dressings sterilized with gamma radiation, such as amnion and pig skin, are a reality in Mexico. These tissues are currently processed in the tissue bank and sterilized in the Gamma Industrial Irradiation Plant; both facilities belong to the Instituto Nacional de Investigaciones Nucleares (ININ) (National Institute of Nuclear Research). With the strong support of the International Atomic Energy Agency, the bank was established at the ININ and the Mexican Ministry of Health issued its sanitary license on July 7, 1999. The Quality Management System of the bank was certified by ISO 9001:2000 on August 1, 2003; the scope of the system is 'Research, Development and Processing of Biological Tissues Sterilized with Gamma Radiation'. At present, more than 150 patients from 16 hospitals have been successfully treated with these tissues. This paper presents a brief description of the tissue processing, as well as the present Mexican clinical experience with children and adult patients who underwent medical treatment with radiosterilized amnion and pig skin, used as biological wound dressings on burns and ocular surface disorders

Current Methods of Evaluating Speech-Language Outcomes for Preschoolers with Communication Disorders: A Scoping Review Using the ICF-CY

Science.gov (United States)

Cunningham, Barbara Jane; Washington, Karla N.; Binns, Amanda; Rolfe, Katelyn; Robertson, Bernadette; Rosenbaum, Peter

2017-01-01

Purpose: The purpose of this scoping review was to identify current measures used to evaluate speech-language outcomes for preschoolers with communication disorders within the framework of the International Classification of Functioning, Disability and Health-Children and Youth Version (ICF-CY; World Health Organization, 2007). Method: The review…

Tissue Banking: Current procedures, ethical consideration and ...

African Journals Online (AJOL)

Tissue banking provides safe and effective cells and tissues for transplantation in reconstruction surgery. Bone, amnion, skin, cartilage, heart valves and xenograft tissues are the most commonly used biological tissues. Acquisition of tissue is dependent on elaborate donor screening criteria based on medical and social ...

Retinoid inhibition of in vitro invasion of human amnion basement membrane by human tumor cells

International Nuclear Information System (INIS)

Fazely, F.; Ledinko, N.; Smith, D.J.

1986-01-01

The biological activity of retinoids was assayed in an in vitro quantitative assay of human tumor cell invasion using human amnion basement membrane (BM). The effects measured were the inhibition of tumor cell migration through the BM and tumor cell degradative enzyme activity on 14 C-proline labeled collagenous and noncollagenous components of the BM. The human lung carcinoma A549 or the human Ewing's sarcoma TC-106 cell lines treated with retinoids for two days were incubated on the BM in the absence of retinoids. A dose-dependent inhibition of cell invasion was produced by retinoids. Among the retinoids tested, the most powerful was retinol acetate which inhibited invasion by 50% of A549 cells at a concentration of 0.009 μg/mL, and of TC-106 cells at 0.07 μg/mL. Retinol acetate inhibited A549 and TC-106 cell growth by approximately 50% at levels over 100-fold higher than those needed for antiinvasive activity. Retinol acetate was about 20 times more potent than retinoic acid and 30 times more potent than retinol palmitate. The model system will be useful for investigating antiinvasive activity of other retinoids as well as other compounds

Current Market Top Business Scopes Trend—A Concurrent Text and Time Series Active Learning Study of NASDAQ and NYSE Stocks from 2012 to 2017

Directory of Open Access Journals (Sweden)

Xiaoping Du

2018-05-01

Full Text Available As information technologies evolve, it has become necessary to examine the changes which have taken place in the top business scopes for both investors and entrepreneurs. To provide an understanding for the trends of the top business scopes in the current market, this article conducts a concurrent text and time series methodology to analyze the stocks in the New York Stock Exchange (NYSE and the National Association of Securities Dealers Automated Quotations (NASDAQ from 2012 to 2017. There is evidence that artificial intelligence and blockchains gained increasing importance for companies during that period. The authors contend that their findings in this paper question the status quo of promising business scopes for companies in the U.S. market.

Effect of barbiturates on radiosensitivity of cells: a comparative study of electrophoretic mobility, colony forming ability and thymidine uptake on human amnion cells

International Nuclear Information System (INIS)

Lalwani, N.D.; Chaubal, K.A.

1980-01-01

Suspensions of human amnion cells were 60 Co γ-irradiated in the presence of phenobarbital or thiobarbital (50 μg/ml). The barbiturates protected the cells against the dose-dependent reduction in electrophoretic mobility (EPM) observed 4 hours after irradiation of untreated cells, although there was an initial decrease in the EPM of treated cells followed by recovery. Treated irradiated cells exhibited greater colony-forming ability than the untreated cells. Pentobarbital and phenobarbital had similar effects, but thiobarbital was not so effective. 3 H-TdR uptake increased within 4 hours of irradiation for the treated cells. The reproductive capacity of the cells was retained at doses as high as 500 rad. The results are discussed with reference to the effects of anaesthetics on cell membranes. (U.K.)

Bariatric surgery and the changing current scope of general surgery practice: implications for general surgery residency training.

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Mostaedi, Rouzbeh; Ali, Mohamed R; Pierce, Jonathan L; Scherer, Lynette A; Galante, Joseph M

2015-02-01

The scope of general surgery practice has evolved tremendously in the last 20 years. However, clinical experience in general surgery residency training has undergone relatively little change. To evaluate the current scope of academic general surgery and its implications on surgical residency. The University HealthSystem Consortium and Association of American Medical Colleges established the Faculty Practice Solution Center (FPSC) to characterize physician productivity. The FPSC is a benchmarking tool for academic medical centers created from revenue data collected from more than 90,000 physicians who practice at 95 institutions across the United States. The FPSC database was queried to evaluate the annual mean procedure frequency per surgeon (PFS) in each calendar year from 2006 through 2011. The associated work relative value units (wRVUs) were also examined to measure physician effort and skill. During the 6-year period, 146 distinct Current Procedural Terminology codes were among the top 100 procedures, and 16 of these procedures ranked in the top 10 procedures in at least 1 year. The top 10 procedures accounted for more than half (range, 52.5%-57.2%) of the total 100 PFS evaluated for each year. Laparoscopic Roux-en-Y gastric bypass was consistently among the top 10 procedures in each year (PFS, 18.2-24.6). The other most frequently performed procedures included laparoscopic cholecystectomy (PFS, 30.3-43.5), upper gastrointestinal tract endoscopy (PFS, 26.5-34.3), mastectomy (PFS, 16.5-35.0), inguinal hernia repair (PFS, 15.5-22.1), and abdominal wall hernia repair (PFS, 21.6-26.1). In all years, laparoscopic Roux-en-Y gastric bypass generated the highest number of wRVUs (wRVUs, 491.0-618.2), and laparoscopic cholecystectomy was regularly the next highest (wRVUs, 335.8-498.7). A significant proportion of academic general surgery is composed of bariatric surgery, yet surgical training does not sufficiently emphasize the necessary exposure to technical expertise

Factors Associated With Full Implementation of Scope of Practice.

Science.gov (United States)

Ganz, Freda DeKeyser; Toren, Orly; Fadlon, Yafit

2016-05-01

To describe whether nurses fully implement their scope of practice; nurses' perceptions of future practice implementation; and the association between scope of practice implementation with professional autonomy and self-efficacy. A descriptive correlational study was conducted using a convenience sample of 145 registered nurses with post-basic certification from two Israeli university hospitals, from May 2012 to September 2013. Five questionnaires were distributed: (a) Demographic and Work Characteristics, (b) Implementation of Scope of Practice, (c) Attitudes Towards Future Practice, (d) Practice Behavior Scale, and (e) Practice Self-Efficacy. Descriptive statistics for all demographic and questionnaire data were analyzed. Two regression models were developed, where current and future implementations were the criterion variables and demographic and work characteristics, professional autonomy, and self-efficacy were the predictors. High levels of professional autonomy, self-efficacy, and attitudes towards future practice were found in contrast to low or moderate levels of current implementation of the full extent of scope of practice. Primary reasons associated with low implementation were lack of relevance to practice and permission to perform the practice. Significant associations were found between professional autonomy, self-efficacy, and attitudes towards future practice, but not with current implementation. Nurses wanted to practice to the full extent of their scope of practice and felt able to do so but were hindered by administrative and not personal barriers. Even though staff nurses with post-basic certification had high levels of professional autonomy and self-efficacy, many were not implementing the full extent of their scope of practice. Similar to findings from around the world, external factors, such as administrative and policy barriers, were found to thwart the full implementation of nurses' full scope of practice. Therefore, practicing nurses

Figures in clinical trial reports: current practice & scope for improvement.

Science.gov (United States)

Pocock, Stuart J; Travison, Thomas G; Wruck, Lisa M

2007-11-19

Most clinical trial publications include figures, but there is little guidance on what results should be displayed as figures and how. To evaluate the current use of figures in Trial reports, and to make constructive suggestions for future practice. We surveyed all 77 reports of randomised controlled trials in five general medical journals during November 2006 to January 2007. The numbers and types of figures were determined, and then each Figure was assessed for its style, content, clarity and suitability. As a consequence, guidelines are developed for presenting figures, both in general and for each specific common type of Figure. Most trial reports contained one to three figures, mean 2.3 per article. The four main types were flow diagram, Kaplan Meier plot, Forest plot (for subgroup analyses) and repeated measures over time: these accounted for 92% of all figures published. For each type of figure there is a considerable diversity of practice in both style and content which we illustrate with selected examples of both good and bad practice. Some pointers on what to do, and what to avoid, are derived from our critical evaluation of these articles' use of figures. There is considerable scope for authors to improve their use of figures in clinical trial reports, as regards which figures to choose, their style of presentation and labelling, and their specific content. Particular improvements are needed for the four main types of figures commonly used.

Figures in clinical trial reports: current practice & scope for improvement

Directory of Open Access Journals (Sweden)

Travison Thomas G

2007-11-01

Full Text Available Abstract Background Most clinical trial publications include figures, but there is little guidance on what results should be displayed as figures and how. Purpose To evaluate the current use of figures in Trial reports, and to make constructive suggestions for future practice. Methods We surveyed all 77 reports of randomised controlled trials in five general medical journals during November 2006 to January 2007. The numbers and types of figures were determined, and then each Figure was assessed for its style, content, clarity and suitability. As a consequence, guidelines are developed for presenting figures, both in general and for each specific common type of Figure. Results Most trial reports contained one to three figures, mean 2.3 per article. The four main types were flow diagram, Kaplan Meier plot, Forest plot (for subgroup analyses and repeated measures over time: these accounted for 92% of all figures published. For each type of figure there is a considerable diversity of practice in both style and content which we illustrate with selected examples of both good and bad practice. Some pointers on what to do, and what to avoid, are derived from our critical evaluation of these articles' use of figures. Conclusion There is considerable scope for authors to improve their use of figures in clinical trial reports, as regards which figures to choose, their style of presentation and labelling, and their specific content. Particular improvements are needed for the four main types of figures commonly used.

Enantioselective cytotoxicity of the insecticide bifenthrin on a human amnion epithelial (FL) cell line

International Nuclear Information System (INIS)

Liu Huigang; Zhao Meirong; Zhang Cong; Ma Yun; Liu Weiping

2008-01-01

Synthetic pyrethroids (SPs) are used in preference to organochlorines and organophosphates due to their high efficiency, low toxicity to mammals, and ready biodegradability. Previous studies reported that enantioselective toxicity of SPs occurs in aquatic toxicity. Several studies have indicated that SPs could lead to oxidative damage in humans or animals which was associated with their toxic effects. Little is known about the differences in the effects of chronic toxicity induced by individual stereoisomers of chiral SPs. The present study was therefore undertaken to evaluate the enantioselectivity in cytotoxicity, genotoxicity caused by bifenthrin (BF) on human amnion epithelial (FL) cell lines and pesticidal activity on target organism. The cell proliferation and cytoflow analysis indicated that 1S-cis-BF presented more toxic effects than 1R-cis-BF above the concentration of 7.5 mg L -1 (p > 0.05). FL cells incubated with 1S-cis-BF exhibited a dose-dependent accumulation of intracellular reactive oxygen species (ROS). In the comet assay, the number of cells with damaged DNA incubated with 1S-cis-BF was more than that with 1R-cis-BF (p 50 values of enantiomer to the target pest on Pieris rapae L. show that 1R-cis-BF was 300 times more active than 1S-cis-BF. These results indicate that the enantioselective toxicity and activity of BF between non-target organism and target organism was reversal. These implications together suggest that assessment of the environmental safety and new pesticides development with chiral centers should consider enantioselectivity

Experiment of amnion epithelial cell suspension liquid used for acute rabbit corneal alkali burn

Directory of Open Access Journals (Sweden)

Yan-Yan Zhang

2017-10-01

Full Text Available AIM: To investigate the effects of amnion epithelial cell(AECsuspension liquid on the biological behavior of the rabbit's corneal epithelium, combined with the in vitro and in vivo experiments. METHODS: The rabbit's corneal epithelium were cultured in the lower chamber of transwell, and AEC suspension liquid was dropwised in the upper chamber. There was only culture medium in the upper chamber of the control group. The proliferation of rabbit's corneal epithelium was observed with CCK-8 automated colorimetry and the expression of PCNA was detected by immunocytochemistry. We used the scratch wound assay to detect the migration of corneal epithelial cell(CEC. The in vivo models were established by placing a 10mm diameter corneal trephine in the center of the cornea, within 1mol/L NaOH for 1min. We divided those into three groups: treatment group of AEC suspension liquid eye drop, AEC suspension liquid subconjunctival injection and the control group without any treatment. Using the slit-lamp biomicroscope and fluorescence staining to observe the cornea per week. After 28d we took the eyeballs with the HE staining. The expression of VEGF was detected by immunohistochemistry. RESULTS: The activity of CEC with AEC treatment was much higher than the control group(PPIn vivo, the inflammation of the corneal and the CNV of the AEC group were all significantly reduced compared with the control group(PPCONCLUSION: AEC suspension liquid can promote the proliferation and migration of the rabbit's corneal epithelium. The potential of AEC suspension liquid as a therapy for acute corneal alkali burn.

Scoping reviews: time for clarity in definition, methods, and reporting.

Science.gov (United States)

Colquhoun, Heather L; Levac, Danielle; O'Brien, Kelly K; Straus, Sharon; Tricco, Andrea C; Perrier, Laure; Kastner, Monika; Moher, David

2014-12-01

The scoping review has become increasingly popular as a form of knowledge synthesis. However, a lack of consensus on scoping review terminology, definition, methodology, and reporting limits the potential of this form of synthesis. In this article, we propose recommendations to further advance the field of scoping review methodology. We summarize current understanding of scoping review publication rates, terms, definitions, and methods. We propose three recommendations for clarity in term, definition and methodology. We recommend adopting the terms "scoping review" or "scoping study" and the use of a proposed definition. Until such time as further guidance is developed, we recommend the use of the methodological steps outlined in the Arksey and O'Malley framework and further enhanced by Levac et al. The development of reporting guidance for the conduct and reporting of scoping reviews is underway. Consistency in the proposed domains and methodologies of scoping reviews, along with the development of reporting guidance, will facilitate methodological advancement, reduce confusion, facilitate collaboration and improve knowledge translation of scoping review findings. Copyright © 2014 Elsevier Inc. All rights reserved.

Tank farm restoration and safe operation, project W-314, upgrade scope summary report (USSR)

International Nuclear Information System (INIS)

Jacobson, R.W.

1997-01-01

This revision to the Project W-314 Upgrade Scope Summary Report (USSR), incorporates changes to the project scope from Alternative Generation Analysis (AGA), customer guidance, and changing requirements. It defines the actual upgrades currently in scope, and provides traceability to the requirements and/or drivers

Licensing Support System: Preliminary data scope analysis

International Nuclear Information System (INIS)

1989-01-01

The purpose of this analysis is to determine the content and scope of the Licensing Support System (LSS) data base. Both user needs and currently available data bases that, at least in part, address those needs have been analyzed. This analysis, together with the Preliminary Needs Analysis (DOE, 1988d) is a first effort under the LSS Design and Implementation Contract toward developing a sound requirements foundation for subsequent design work. These reports are preliminary. Further refinements must be made before requirements can be specified in sufficient detail to provide a basis for suitably specific system specifications. This document provides a baseline for what is known at this time. Additional analyses, currently being conducted, will provide more precise information on the content and scope of the LSS data base. 23 refs., 4 figs., 8 tabs

Scope Definition

DEFF Research Database (Denmark)

Bjørn, Anders; Owsianiak, Mikołaj; Laurent, Alexis

2018-01-01

The scope definition is the second phase of an LCA. It determines what product systems are to be assessed and how this assessment should take place. This chapter teaches how to perform a scope definition. First, important terminology and key concepts of LCA are introduced. Then, the nine items...... making up a scope definition are elaborately explained: (1) Deliverables. (2) Object of assessment, (3) LCI modelling framework and handling of multifunctional processes, (4) System boundaries and completeness requirements, (5) Representativeness of LCI data, (6) Preparing the basis for the impact...... assessment, (7) Special requirements for system comparisons, (8) Critical review needs and (9) Planning reporting of results. The instructions relate both to the performance and reporting of a scope definition and are largely based on ILCD....

Low-Frequency Pulsed Current Versus Kilohertz-Frequency Alternating Current: A Scoping Literature Review.

Science.gov (United States)

Vaz, Marco Aurélio; Frasson, Viviane Bortoluzzi

2018-04-01

To compare the effectiveness of low-frequency pulsed current versus kilohertz-frequency alternating current in terms of evoked force, discomfort level, current intensity, and muscle fatigability; to discuss the physiological mechanisms of each neuromuscular electrical stimulation type; and to determine if kilohertz-frequency alternating current is better than low-frequency pulsed current for clinical treatment. Articles were obtained from PubMed, Scopus, Cochrane Central Register of Controlled Trials, CINAHL, MEDLINE, and SPORTSDiscus databases using the terms Russian current or kilohertz current or alternating current or pulsed current or Aussie current and torque or discomfort or fatigue or current intensity, and through citation tracking up to July 2017. Two independent reviewers selected studies comparing the use of the 2 neuromuscular electrical stimulation currents. Studies describing maximal current intensity tolerated and the main effects of the 2 different current types on discomfort, muscle force, and fatigability were independently reviewed. Data were systematized according to (1) methodology; (2) electrical current characteristics; and (3) outcomes on discomfort level, evoked force, current intensity, and muscle fatigability. The search revealed 15 articles comparing the 2 current types. Kilohertz-frequency alternated current generated equal or less force, similar discomfort, similar current intensity for maximal tolerated neuromuscular electrical stimulation, and more fatigue compared with low-frequency pulsed current. Similar submaximal levels of evoked force revealed higher discomfort and current intensity for kilohertz-frequency alternated current compared with low-frequency pulsed current. Available evidence does not support the idea that kilohertz-frequency alternated current is better than low-frequency pulsed current for strength training and rehabilitation. Copyright © 2017 American Congress of Rehabilitation Medicine. Published by Elsevier

The SCOPE Mission

International Nuclear Information System (INIS)

Fujimoto, M.; Tsuda, Y.; Saito, Y.; Shinohara, I.; Takashima, T.; Matsuoka, A.; Kojima, H.; Kasaba, Y.

2009-01-01

In order to reach the new horizon of the space physics research, the Plasma Universe, via in-situ measurements in the Earth's magnetosphere, SCOPE will perform formation flying observations combined with high-time resolution electron measurements. The simultaneous multi-scale observations by SCOPE of various plasma dynamical phenomena will enable data-based study of the key space plasma processes from the cross-scale coupling point of view. Key physical processes to be studied are magnetic reconnection under various boundary conditions, shocks in space plasma, collisionless plasma mixing at the boundaries, and physics of current sheets embedded in complex magnetic geometries. The SCOPE formation is made up of 5 spacecraft and is put into the equatorial orbit with the apogee at 30 Re (Re: earth radius). One of the spacecraft is a large mother ship which is equipped with a full suite of particle detectors including ultra-high time resolution electron detector. Among other 4 small spacecraft, one remains near (∼10 km) the mother ship and the spacecraft-pair will focus on the electron-scale physics. Others at the distance of 100∼3000 km(electron∼ion spatial scales) from the mother ship will monitor plasma dynamics surrounding the mother-daughter pair. There is lively on-going discussion on Japan-Europe international collaboration (ESA's Cross-Scale), which would certainly make better the coverage over the scales of interest and thus make the success of the mission, i.e., clarifying the multi-scale nature of the Plasma Universe, to be attained at an even higher level.

Contribution of aquaporin 9 and multidrug resistance-associated protein 2 to differential sensitivity to arsenite between primary cultured chorion and amnion cells prepared from human fetal membranes

International Nuclear Information System (INIS)

Yoshino, Yuta; Yuan, Bo; Kaise, Toshikazu; Takeichi, Makoto; Tanaka, Sachiko; Hirano, Toshihiko; Kroetz, Deanna L.; Toyoda, Hiroo

2011-01-01

Arsenic trioxide (arsenite, As III ) has shown a remarkable clinical efficacy, whereas its side effects are still a serious concern. Therefore, it is critical to understand the effects of As III on human-derived normal cells for revealing the mechanisms underlying these side effects. We examined the effects of As III on primary cultured chorion (C) and amnion (A) cells prepared from human fetal membranes. A significant dose-dependent As III -mediated cytotoxicity was observed in the C-cells accompanied with an increase of lactate dehydrogenase (LDH) release. Higher concentrations of As III were required for the A-cells to show cytotoxicity and LDH release, suggesting that the C-cells were more sensitive to As III than the A-cells. The expression levels of aquaporin 9 (AQP9) were approximately 2 times higher in the C-cells than those in the A-cells. Both intracellular arsenic accumulation and its cytotoxicity in the C-cells were significantly abrogated by sorbitol, a competitive AQP9 inhibitor, in a dose-dependent manner. The protein expression levels of multidrug resistance-associated protein (MRP) 2 were downregulated by As III in the C-cells, but not in the A-cells. No significant differences in the expression levels of MRP1 were observed between C- and A-cells. The protein expression of P-glycoprotein (P-gp) was hardly detected in both cells, although a detectable amount of its mRNA was observed. Cyclosporine A, a broad-spectrum inhibitor for ABC transporters, and MK571, a MRP inhibitor, but not PGP-4008, a P-gp specific inhibitor, potently sensitized both cells to As III -mediated cytotoxicity. These results suggest that AQP9 and MRP2 are involved in controlling arsenic accumulation in these normal cells, which then contribute to differential sensitivity to As III cytotoxicity between these cells. -- Highlights: ► Examination of effect of As III on primary cultured chorion (C) and amnion (A) cells. ► Dose-dependent As III -mediated cytotoxicity in C

Full-scope training simulators

International Nuclear Information System (INIS)

Ugedo, E.

1986-01-01

The following topics to be covered in this report are: Reasons justifying the use of full-scope simulators for operator qualification. Full-scope simulator description: the control room, the physical models, the computer complex, the instructor's console. Main features of full-scope simulators. Merits of simulator training. The role of full-scope simulators in the training programs. The process of ordering and acquiring a full-scope simulator. Maintaining and updating simulator capabilities. (orig./GL)

PROJECT SCOPE MANAGEMENT PROCESS

Directory of Open Access Journals (Sweden)

Yana Derenskaya

2018-01-01

Full Text Available The purpose of the article is to define the essence of project scope management process, its components, as well as to develop an algorithm of project scope management in terms of pharmaceutical production. Methodology. To carry out the study, available information sources on standards of project management in whole and elements of project scope management in particular are analysed. Methods of system and structural analysis, logical generalization are used to study the totality of subprocesses of project scope management, input and output documents, and to provide each of them. Methods of network planning are used to construct a precedence diagram of project scope management process. Results of the research showed that components of the project scope management are managing the scope of the project product and managing the content of project work. It is the second component is investigated in the presented work as a subject of research. Accordingly, it is defined that project scope management process is to substantiate and bring to the realization the necessary amount of work that ensures the successful implementation of the project (achievement of its goal and objectives of individual project participants. It is also determined that the process of managing the project scope takes into account the planning, definition of the project scope, creation of the structure of project work, confirmation of the scope and management of the project scope. Participants of these subprocesses are: customer, investor, and other project participants – external organizations (contractors of the project; project review committee; project manager and project team. It is revealed that the key element of planning the project scope is the formation of the structure of design work, the justification of the number of works, and the sequence of their implementation. It is recommended to use the following sequence of stages for creating the structure of project work

Amnion s and radio-sterilized porcine skin use as potential matrices for the development of human skin substitutes; Uso de amnios y piel porcina radioesterilizados como matrices potenciales para el desarrollo de sustitutos de piel humana

Energy Technology Data Exchange (ETDEWEB)

Martinez P, M. E.; Reyes F, M. L.; Reboyo B, D. [ININ, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico); Velasquillo M, M. C.; Sanchez S, R.; Brena M, A. M.; Ibarra P, J. C., E-mail: esther.martinez@inin.gob.mx [Instituto Nacional de Rehabilitacion, Calz. Mexico-Xochimilco No. 289, Col. Arenal de Guadalupe, 14389 Mexico D. F. (Mexico)

2014-10-15

The injuries by burns constitute a primordial problem of public health; they cause a high mortality index, severe physical and psychological disability, etc. The autologous skin transplant is the replacement therapy recommended for its treatment, but in patients that present a high percentage of burnt skin; this is not possible to carry out. Another strategy is the transplant of donated skin; however, due to the little donation that exists in our country is not very feasible to apply this treatment. A challenge of the tissues engineering is to develop biological skin substitutes, based on cells and amnion s, favoring the cutaneous regeneration and quick repair of injuries, diminishing this way the hospitalization expenses. At present skin substitutes that can equal to the same skin do not exist. On the other hand, the mesenchymal stromal cells (Msc) represent an alternative to achieve this objective; since has been demonstrated that the Msc participate in the tissue repair by means of inhibition of pro-inflammatory cytokines and differentiation to dermal fibroblasts and keratinocytes. To apply the Msc in cutaneous injuries a support material is required that to allow transplanting these cells to a lesion or burn. The radio-sterilized human amnion and the radio-sterilized porcine skin, processed by the Radio-Sterilized Tissues Bank of the Instituto Nacional de Investigaciones Nucleares (ININ), are biomaterials that are used as temporary cutaneous coverings. We suppose that these two matrices will be appropriate for the growth and maintenance in cultivation of the Msc, to generate two biological skin substitutes, in collaboration with the Biotechnology Laboratory of the Instituto Nacional de Rehabilitacion. (Author)

FLEXIBLE SCOPE IN ACCREDITATION - INTRODUCING VAGUENESS OR BETTER EXPRESSION OF SCOPE

Directory of Open Access Journals (Sweden)

Miloš Jelić

2007-09-01

Full Text Available Historically, laboratory accreditation has been grounded on fixed scope of accreditation to establish precisely and unambiguously the range of tests and calibrations covered by a granted accreditation. By the time elapsed it was noticed that such approach sometimes appears to be restrictive since it constrains new or modified methods to be added to a laboratory's scope, even where competence in this general area has already been demonstrated. Accreditation of a flexible scope places more of the responsibility onto the laboratory itself because it imposes to the laboratory to establish and maintain management system that can control its proposed approach. Flexible scope of accreditation yields benefit to all accreditation stakeholders but, on the other hand, introduces more requiring interpretations of relevant standard clauses and includes the bounds of the scope which are defined in more distinct way.

On the Scope of Egalitarian Justice

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Joseph Heath

2006-05-01

Full Text Available It is not clear whether the social contract is supposed to merely supplement the unequal gains that individuals are able to make through the exercise of their natural endowments with a set of equal gains secured through social cooperation, or whether the social contract must also compensate individuals for the effects of these natural inequalities, so that they literally become all equal. The issue concerns, in effect, whether natural inequality falls within the scope of egalitarian justice. I think it is fair to say that the majority of egalitarians assume that the principle of equality imposes an obligation to redress natural inequality. Yet there is no consensus on this issue. David Gauthier has made the rejection of the principle of redress a central component of his project. It has often escaped notice that John Rawls also rejects the principle of redress. Thus it is not just anti-egalitarians who reject the principle of redress. There is a current of egalitarian thought– which we might call, for lack of a better term, narrow-scope egalitarianism – which also rejects this principle. In this paper, I would like to show that there is considerable wisdom in the narrow-scope egalitarian position. Many of the problems that lead theorists to reject egalitarianism in its entirety are a consequence, not of the principle of equality per se, but rather of the commitment to redress natural inequality. The narrow-scope view avoids all of these difficulties.

Harry Potter and the sorcerer's scope: latent scope biases in explanatory reasoning.

Science.gov (United States)

Khemlani, Sangeet S; Sussman, Abigail B; Oppenheimer, Daniel M

2011-04-01

What makes a good explanation? We examine the function of latent scope, i.e., the number of unobserved phenomena that an explanation can account for. We show that individuals prefer narrow latent scope explanations-those that account for fewer unobserved effects-to broader explanations. In Experiments 1a-d, participants found narrow latent scope explanations to be both more satisfying and more likely. In Experiment 2 we directly manipulated base rate information and again found a preference for narrow latent scope explanations. Participants in Experiment 3 evaluated more natural explanations of unexpected observations, and again displayed a bias for narrow latent scope explanations. We conclude by considering what this novel bias tells us about how humans evaluate explanations and engage in causal reasoning.

Inflammatory gene regulatory networks in amnion cells following cytokine stimulation: translational systems approach to modeling human parturition.

Directory of Open Access Journals (Sweden)

Ruth Li

Full Text Available A majority of the studies examining the molecular regulation of human labor have been conducted using single gene approaches. While the technology to produce multi-dimensional datasets is readily available, the means for facile analysis of such data are limited. The objective of this study was to develop a systems approach to infer regulatory mechanisms governing global gene expression in cytokine-challenged cells in vitro, and to apply these methods to predict gene regulatory networks (GRNs in intrauterine tissues during term parturition. To this end, microarray analysis was applied to human amnion mesenchymal cells (AMCs stimulated with interleukin-1β, and differentially expressed transcripts were subjected to hierarchical clustering, temporal expression profiling, and motif enrichment analysis, from which a GRN was constructed. These methods were then applied to fetal membrane specimens collected in the absence or presence of spontaneous term labor. Analysis of cytokine-responsive genes in AMCs revealed a sterile immune response signature, with promoters enriched in response elements for several inflammation-associated transcription factors. In comparison to the fetal membrane dataset, there were 34 genes commonly upregulated, many of which were part of an acute inflammation gene expression signature. Binding motifs for nuclear factor-κB were prominent in the gene interaction and regulatory networks for both datasets; however, we found little evidence to support the utilization of pathogen-associated molecular pattern (PAMP signaling. The tissue specimens were also enriched for transcripts governed by hypoxia-inducible factor. The approach presented here provides an uncomplicated means to infer global relationships among gene clusters involved in cellular responses to labor-associated signals.

Hanford Waste Vitrification Project Building limited scope risk assessment

International Nuclear Information System (INIS)

Braun, D.J.; Lindberg, S.E.; Reardon, M.F.; Wilson, G.P.

1992-10-01

A limited scope risk assessment was performed on the preliminary design of a high-level waste interim storage facility. The Canister Storage Building (CSB) facility will be built to support remediation at the US Department of Energy Hanford Site in Washington State. The CSB will be part of the support facilities for a high level Hanford Waste Vitrification Plant (HWVP). The limited scope risk assessment is based on a preliminary design which uses forced air circulation systems to move air through the building vault. The current building design calls for natural circulation to move air through the building vault

Contribution of aquaporin 9 and multidrug resistance-associated protein 2 to differential sensitivity to arsenite between primary cultured chorion and amnion cells prepared from human fetal membranes

Energy Technology Data Exchange (ETDEWEB)

Yoshino, Yuta [Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392 (Japan); Yuan, Bo, E-mail: yuanbo@toyaku.ac.jp [Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392 (Japan); Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, 1550 4th St, RH584E Box 2911 San Francisco, CA 94158-2911 (United States); Kaise, Toshikazu [Laboratory of Environmental Chemodynamics, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392 (Japan); Takeichi, Makoto [Yoneyama Maternity Hospital, 2-12 Shin-machi, Hachioji, Tokyo 192-0065 (Japan); Tanaka, Sachiko; Hirano, Toshihiko [Department of Clinical Pharmacology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392 (Japan); Kroetz, Deanna L. [Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, 1550 4th St, RH584E Box 2911 San Francisco, CA 94158-2911 (United States); Toyoda, Hiroo [Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392 (Japan)

2011-12-15

Arsenic trioxide (arsenite, As{sup III}) has shown a remarkable clinical efficacy, whereas its side effects are still a serious concern. Therefore, it is critical to understand the effects of As{sup III} on human-derived normal cells for revealing the mechanisms underlying these side effects. We examined the effects of As{sup III} on primary cultured chorion (C) and amnion (A) cells prepared from human fetal membranes. A significant dose-dependent As{sup III}-mediated cytotoxicity was observed in the C-cells accompanied with an increase of lactate dehydrogenase (LDH) release. Higher concentrations of As{sup III} were required for the A-cells to show cytotoxicity and LDH release, suggesting that the C-cells were more sensitive to As{sup III} than the A-cells. The expression levels of aquaporin 9 (AQP9) were approximately 2 times higher in the C-cells than those in the A-cells. Both intracellular arsenic accumulation and its cytotoxicity in the C-cells were significantly abrogated by sorbitol, a competitive AQP9 inhibitor, in a dose-dependent manner. The protein expression levels of multidrug resistance-associated protein (MRP) 2 were downregulated by As{sup III} in the C-cells, but not in the A-cells. No significant differences in the expression levels of MRP1 were observed between C- and A-cells. The protein expression of P-glycoprotein (P-gp) was hardly detected in both cells, although a detectable amount of its mRNA was observed. Cyclosporine A, a broad-spectrum inhibitor for ABC transporters, and MK571, a MRP inhibitor, but not PGP-4008, a P-gp specific inhibitor, potently sensitized both cells to As{sup III}-mediated cytotoxicity. These results suggest that AQP9 and MRP2 are involved in controlling arsenic accumulation in these normal cells, which then contribute to differential sensitivity to As{sup III} cytotoxicity between these cells. -- Highlights: Black-Right-Pointing-Pointer Examination of effect of As{sup III} on primary cultured chorion (C) and amnion

The Current Landscape of Transitions of Care Practice Models: A Scoping Review.

Science.gov (United States)

Rochester-Eyeguokan, Charmaine D; Pincus, Kathleen J; Patel, Roshni S; Reitz, Shirley J

2016-01-01

Transitions of care (TOC) are a set of actions to ensure patient coordination and continuity of care as patients transfer between different locations or levels. During transitions associated with chronic or acute illness, vulnerable patients may be placed at risk with fragmented systems compromising their health and safety. In addition, poor care transitions also have an enormous impact on health care spending. The primary objective of this scoping review is to summarize the current landscape of practice models that deliver TOC services in the United States. The secondary objective is to use the information to characterize the current state of best practice models. A search of the PubMed, Embase, Cumulative Index to Nursing and Allied Health Literature, Web of Science, International Pharmaceutical Abstracts, National Center for Biotechnology Information at the U.S. National Library of Medicine, and Cochrane Library databases (January 1, 2000-April 13, 2015) for articles pertaining to TOC models, limited to U.S. studies published in the English language with human subjects, gleaned 1362 articles. An additional 26 articles were added from the gray literature. Articles meeting inclusion criteria underwent a second review and were categorized into four groups: background information, original TOC research articles not evaluating practice model interventions, original TOC research articles describing practice models, and systematic or Cochrane reviews. The reviewers met weekly to discuss the challenges and resolve disagreements regarding literature reviews with consensus before progressing. A total of 188 articles describing TOC practice models met the inclusion criteria. Despite the strengths of several quality TOC models, none satisfied all the components recommended by leading experts. Multimodal interventions by multidisciplinary teams appear to represent a best practice model for TOC to improve patient outcomes and reduce readmissions, but one size does not fit all

Human amnion-derived mesenchymal stem cells protect against UVA irradiation-induced human dermal fibroblast senescence, in vitro

Science.gov (United States)

Zhang, Chunli; Yuchi, Haishen; Sun, Lu; Zhou, Xiaoli; Lin, Jinde

2017-01-01

The aim of the present study was to determine if human amnion-derived mesenchymal stem cells (HAMSCs) exert a protective effect on ultraviolet A (UVA) irradiation-induced human dermal fibroblast (HDF) senescence. A senescence model was constructed as follows: HDFs (104–106 cells/well) were cultured in a six-well plate in vitro and then exposed to UVA irradiation at 9 J/cm2 for 30 min. Following the irradiation period, HDFs were co-cultured with HAMSCs, which were seeded on transwells. A total of 72 h following the co-culturing, senescence-associated β-galactosidase staining was performed and reactive oxygen species (ROS) content and mitochondrial membrane potential (Δψm) were detected in the HDFs via flow cytometric analysis. The results demonstrated that the percentage of HDFs, detected via staining with X-gal, were markedly decreased when co-cultured with human HAMSCs, compared with the group that were not co-cultured. The ROS content was decreased and the mitochondrial membrane potential (Δψm) recovered in cells treated with UVA and HAMSCs, compared with that of cells treated with UVA alone. Reverse transcription-quantitative polymerase chain reaction revealed the significant effects of HAMSCs on the HDF senescence marker genes p53 and matrix metalloproteinase-1 mRNA expression. In addition to this, western blot analysis verified the effects of HAMSCs on UVA induced senescence, providing a foundation for novel regenerative therapeutic methods. Furthermore, the results suggested that activation of the extracellular-signal regulated kinase 1/2 mitogen activated protein kinase signal transduction pathway, is essential for the HAMSC-mediated UVA protective effects. The decrease in ROS content additionally indicated that HAMSCs may exhibit the potential to treat oxidative stress-mediated UVA skin senescence in the future. PMID:28627622

The present-day scope of practice and services of the traditional healer in South Africa

Directory of Open Access Journals (Sweden)

Gabriel Louw

2016-12-01

Full Text Available Background The scope of practice of the traditional healer in South Africa is not guided or circumscribed by any statutory mandate at present. The traditional healer’s practice and services are currently based on and driven by the supernatural and the afterlife, lacking not only a scientific foundation, but also legal constraint. Aims This study aimed to determine and describe the present-day scope of practice and services of the South African traditional healer. Methods This is an exploratory and descriptive study that makes use of an historical approach by means of investigation and a literature review. The emphasis is on using current documentation like articles, books and newspapers as primary sources to reflect on the scope of practice and services of the South African traditional healer. The findings are offered in narrative form. Results There is no established curriculum and practice culture to serve as an evaluation and descriptive criteria for the present-day traditional healer’s scope of practice. Conclusion The South African traditional healer’s practice and rights are unwritten and legally unregulated, especially when viewed against in comparison with the current practice customs, traditions and rights of the South African statutorily regulated healthcare practitioners.

LogScope

Science.gov (United States)

Havelund, Klaus; Smith, Margaret H.; Barringer, Howard; Groce, Alex

2012-01-01

LogScope is a software package for analyzing log files. The intended use is for offline post-processing of such logs, after the execution of the system under test. LogScope can, however, in principle, also be used to monitor systems online during their execution. Logs are checked against requirements formulated as monitors expressed in a rule-based specification language. This language has similarities to a state machine language, but is more expressive, for example, in its handling of data parameters. The specification language is user friendly, simple, and yet expressive enough for many practical scenarios. The LogScope software was initially developed to specifically assist in testing JPL s Mars Science Laboratory (MSL) flight software, but it is very generic in nature and can be applied to any application that produces some form of logging information (which almost any software does).

Current ornithology

CERN Document Server

1983-01-01

The appearance of the first volume of a projected series is the occasion for comment on scope, aims, and genesis of the work. The scope of Current Ornithology is all of the biology of birds. Ornithology, as a whole-organism science, is concerned with birds at every level of bi­ ological organization, from the molecular to the community, at least from the Jurassic to the present time, and over every scholarly discipline in which bird biology is done; to say this is merely to expand a dic­ tionary definition of "ornithology. " The aim of the work, to be realized over several volumes, is to present reviews or position statements con­ cerning the active fields of ornithological research. The reviews will be relatively short, and often will be done from the viewpoint of a readily­ identified group or school. Such a work could have come into being at any time within the past fifty years, but that Current Ornithology appears now is a result of events that are only seven to eight years old. One important event wa...

76 FR 17577 - Increased Scope of Coverage for Electric Motors

Science.gov (United States)

2011-03-30

... Scope of Coverage for Electric Motors AGENCY: Office of Energy Efficiency and Renewable Energy... conservation standards for electric motors. Specifically, DOE seeks information to assist DOE in determining whether to develop energy conservation standards for certain types of electric motors that are currently...

Combined Amplification and Sound Generation for Tinnitus: A Scoping Review.

Science.gov (United States)

Tutaj, Lindsey; Hoare, Derek J; Sereda, Magdalena

In most cases, tinnitus is accompanied by some degree of hearing loss. Current tinnitus management guidelines recognize the importance of addressing hearing difficulties, with hearing aids being a common option. Sound therapy is the preferred mode of audiological tinnitus management in many countries, including in the United Kingdom. Combination instruments provide a further option for those with an aidable hearing loss, as they combine amplification with a sound generation option. The aims of this scoping review were to catalog the existing body of evidence on combined amplification and sound generation for tinnitus and consider opportunities for further research or evidence synthesis. A scoping review is a rigorous way to identify and review an established body of knowledge in the field for suggestive but not definitive findings and gaps in current knowledge. A wide variety of databases were used to ensure that all relevant records within the scope of this review were captured, including gray literature, conference proceedings, dissertations and theses, and peer-reviewed articles. Data were gathered using scoping review methodology and consisted of the following steps: (1) identifying potentially relevant records; (2) selecting relevant records; (3) extracting data; and (4) collating, summarizing, and reporting results. Searches using 20 different databases covered peer-reviewed and gray literature and returned 5959 records. After exclusion of duplicates and works that were out of scope, 89 records remained for further analysis. A large number of records identified varied considerably in methodology, applied management programs, and type of devices. There were significant differences in practice between different countries and clinics regarding candidature and fitting of combination aids, partly driven by the application of different management programs. Further studies on the use and effects of combined amplification and sound generation for tinnitus are

The Current Status of STEM Education Research

Science.gov (United States)

Brown, Josh

2012-01-01

This paper explores the current Science, Technology, Engineering and Mathematics (STEM) education research base through an analysis of articles from eight journals focused on the STEM disciplines. Analyzed are both practitioner and research publications to determine the current scope of STEM education research, where current STEM education…

FedScope Employment Cubes

Data.gov (United States)

Office of Personnel Management — This raw data set provides Federal civilian employee population data. The scope of this raw data set includes all data elements used in the creation of the FedScope...

Comparative study of regenerative effects of mesenchymal stem cells derived from placental amnion, chorion and umbilical cord on dermal wounds.

Science.gov (United States)

Ertl, Juliane; Pichlsberger, Melanie; Tuca, Alexandru-Cristian; Wurzer, Paul; Fuchs, Jakob; Geyer, Stefan H; Maurer-Gesek, Barbara; Weninger, Wolfgang J; Pfeiffer, Dagmar; Bubalo, Vladimir; Parvizi, Daryousch; Kamolz, Lars-Peter; Lang, Ingrid

2018-05-01

Mesenchymal stem/stromal cells derived from human term placentas (PMSCs) are novel therapeutic agents and more topical than ever. Here we evaluated the effects of three types of PMSCs on wound healing in an in vivo mouse model: Amnion-derived MSCs (AMSCs), blood vessel-derived MSCs (BV-MSCs) from the chorionic plate and Wharton's jelly-derived MSCs (WJ-MSCs) from the umbilical cord. We topically applied PMSCs onto skin wounds in mice using the dermal substitute Matriderm ® as carrier and evaluated wound healing parameters. In addition, we investigated the effects of all PMSC types under co-application with placental endothelial cells (PLECs). After 8 days, we compared the percent of wound closure and the angiogenic potential between all groups. AMSCs, BV-MSCs and WJ-MSCs significantly induced a faster healing and a higher number of blood vessels in the wound when compared to controls (Matriderm ® -alone). PLECs did not further improve the advantageous effects of PMSC-treatment. Quantitative data and 3D analysis by high resolution episcopic microscopy confirmed a lower density of vessels in Matriderm ® /PMSCs/PLECs co-application compared to Matriderm ® /PMSCs treatment. Results indicate that all three PMSC types exert similar beneficial effects on wound closure and neovascularization in our mouse model. Using Matriderm ® as carrier for PMSCs propagates rapid cell migration towards the wound area that allows a fast and clinically practicable method for stem cell application. These promising effects warrant further investigation in clinical trials. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Scope of physician procedures independently billed by mid-level providers in the office setting.

Science.gov (United States)

Coldiron, Brett; Ratnarathorn, Mondhipa

2014-11-01

Mid-level providers (nurse practitioners and physician assistants) were originally envisioned to provide primary care services in underserved areas. This study details the current scope of independent procedural billing to Medicare of difficult, invasive, and surgical procedures by medical mid-level providers. To understand the scope of independent billing to Medicare for procedures performed by mid-level providers in an outpatient office setting for a calendar year. Analyses of the 2012 Medicare Physician/Supplier Procedure Summary Master File, which reflects fee-for-service claims that were paid by Medicare, for Current Procedural Terminology procedures independently billed by mid-level providers. Outpatient office setting among health care providers. The scope of independent billing to Medicare for procedures performed by mid-level providers. In 2012, nurse practitioners and physician assistants billed independently for more than 4 million procedures at our cutoff of 5000 paid claims per procedure. Most (54.8%) of these procedures were performed in the specialty area of dermatology. The findings of this study are relevant to safety and quality of care. Recently, the shortage of primary care clinicians has prompted discussion of widening the scope of practice for mid-level providers. It would be prudent to temper widening the scope of practice of mid-level providers by recognizing that mid-level providers are not solely limited to primary care, and may involve procedures for which they may not have formal training.

32 CFR 989.18 - Scoping.

Science.gov (United States)

2010-07-01

... ANALYSIS PROCESS (EIAP) § 989.18 Scoping. (a) After publication of the NOI for an EIS, the EPF must... public. The result of scoping is that the proponent and EPF determine the range of actions, alternatives, and impacts to be considered in the EIS (40 CFR 1508.25). The EPF must send scripts for scoping...

CMS Phase II Upgrade Scope Document

CERN Document Server

Butler, J; Klute, M; Mans, J; Silvestris, L; on behalf of the CMS, Collaboration; CERN. Geneva. The LHC experiments Committee; LHCC

2015-01-01

The High-Luminosity LHC (HL-LHC) has been identified as the highest priority program in High Energy Physics by both the European Strategy Group and the US Particle Physics Project Prioritization Panel. To fulfil the full potential of this program, which includes the study of the nature of the Higgs boson, the investigation of the properties of any newly discovered particles in the upcoming LHC runs, and the extension of the mass reach for further discoveries, an integrated luminosity of 3000 fb-1 will have to be accumulated by the end of the program. In preparation for operation at the HL-LHC , CMS has documented the necessary upgrades and their expected costs in a Technical Proposal submitted to the CERN LHC Committee (LHCC) in mid-2015. The material presented in the current “Scope Document” provides additional information to assist the LHCC and the CERN Resource Review Board (RRB) in their review of the CMS upgrade. The document commences with a summary of the process followed to develop the scope of t...

Graphical Presentation of Patient-Treatment Interaction Elucidated by Continuous Biomarkers. Current Practice and Scope for Improvement.

Science.gov (United States)

Shen, Yu-Ming; Le, Lien D; Wilson, Rory; Mansmann, Ulrich

2017-01-09

. In our review, a total of seven methodological papers and five clinical reports used CBPTI plots which we categorized into four types: those that distinguish the outcome effect for each treatment group; those that show the outcome differences between treatment groups (by either partitioning all individuals into subpopulations or modelling the functional form of the interaction); those that evaluate the proportion of population impact of the biomarker; and those that show the classification accuracy of the biomarker. The current practice of utilizing CBPTI plots in clinical reports suffers from methodological shortcomings: the lack of presentation of statistical uncertainty, the outcome measure scaled by relative unit instead of absolute unit, incorrect use of benchmarks, and being non-informative in answering clinical questions. There is considerable scope for improvement in the graphical representation of CBPTI in clinical reports. The current challenge is to develop instruments for high-quality graphical plots which not only convey quantitative concepts to readers with limited statistical knowledge, but also facilitate medical decision-making.

Amniotic Mesenchymal Stromal Cells Exhibit Preferential Osteogenic and Chondrogenic Differentiation and Enhanced Matrix Production Compared With Adipose Mesenchymal Stromal Cells.

Science.gov (United States)

Topoluk, Natasha; Hawkins, Richard; Tokish, John; Mercuri, Jeremy

2017-09-01

Therapeutic efficacy of various mesenchymal stromal cell (MSC) types for orthopaedic applications is currently being investigated. While the concept of MSC therapy is well grounded in the basic science of healing and regeneration, little is known about individual MSC populations in terms of their propensity to promote the repair and/or regeneration of specific musculoskeletal tissues. Two promising MSC sources, adipose and amnion, have each demonstrated differentiation and extracellular matrix (ECM) production in the setting of musculoskeletal tissue regeneration. However, no study to date has directly compared the differentiation potential of these 2 MSC populations. To compare the ability of human adipose- and amnion-derived MSCs to undergo osteogenic and chondrogenic differentiation. Controlled laboratory study. MSC populations from the human term amnion were quantified and characterized via cell counting, histologic assessment, and flow cytometry. Differentiation of these cells in comparison to commercially purchased human adipose-derived mesenchymal stromal cells (hADSCs) in the presence and absence of differentiation media was evaluated via reverse transcription polymerase chain reaction (PCR) for bone and cartilage gene transcript markers and histology/immunohistochemistry to examine ECM production. Analysis of variance and paired t tests were performed to compare results across all cell groups investigated. The authors confirmed that the human term amnion contains 2 primary cell types demonstrating MSC characteristics-(1) human amniotic epithelial cells (hAECs) and (2) human amniotic mesenchymal stromal cells (hAMSCs)-and each exhibited more than 90% staining for MSC surface markers (CD90, CD105, CD73). Average viable hAEC and hAMSC yields at harvest were 2.3 × 10 6 ± 3.7 × 10 5 and 1.6 × 10 6 ± 4.7 × 10 5 per milliliter of amnion, respectively. As well, hAECs and hAMSCs demonstrated significantly greater osteocalcin ( P = .025), aggrecan ( P

Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche

Science.gov (United States)

Shao, Yue; Taniguchi, Kenichiro; Gurdziel, Katherine; Townshend, Ryan F.; Xue, Xufeng; Yong, Koh Meng Aw; Sang, Jianming; Spence, Jason R.; Gumucio, Deborah L.; Fu, Jianping

2017-04-01

Amniogenesis--the development of amnion--is a critical developmental milestone for early human embryogenesis and successful pregnancy. However, human amniogenesis is poorly understood due to limited accessibility to peri-implantation embryos and a lack of in vitro models. Here we report an efficient biomaterial system to generate human amnion-like tissue in vitro through self-organized development of human pluripotent stem cells (hPSCs) in a bioengineered niche mimicking the in vivo implantation environment. We show that biophysical niche factors act as a switch to toggle hPSC self-renewal versus amniogenesis under self-renewal-permissive biochemical conditions. We identify a unique molecular signature of hPSC-derived amnion-like cells and show that endogenously activated BMP-SMAD signalling is required for the amnion-like tissue development by hPSCs. This study unveils the self-organizing and mechanosensitive nature of human amniogenesis and establishes the first hPSC-based model for investigating peri-implantation human amnion development, thereby helping advance human embryology and reproductive medicine.

Implementation science: a reappraisal of our journal mission and scope.

Science.gov (United States)

Foy, Robbie; Sales, Anne; Wensing, Michel; Aarons, Gregory A; Flottorp, Signe; Kent, Bridie; Michie, Susan; O'Connor, Denise; Rogers, Anne; Sevdalis, Nick; Straus, Sharon; Wilson, Paul

2015-04-17

The implementation of research findings into healthcare practice has become increasingly recognised as a major priority for researchers, service providers, research funders and policymakers over the past decade. Nine years after its establishment, Implementation Science, an international online open access journal, currently publishes over 150 articles each year. This is fewer than 30% of those submitted for publication. The majority of manuscript rejections occur at the point of initial editorial screening, frequently because we judge them to fall outside of journal scope. There are a number of common reasons as to why manuscripts are rejected on grounds of scope. Furthermore, as the field of implementation research has evolved and our journal submissions have risen, we have, out of necessity, had to become more selective in what we publish. We have also expanded our scope, particularly around patient-mediated and population health interventions, and will monitor the impact of such changes. We hope this editorial on our evolving priorities and common reasons for rejection without peer review will help authors to better judge the relevance of their papers to Implementation Science.

Oxidizer Scoping Studies

Energy Technology Data Exchange (ETDEWEB)

Chancellor, Christopher John [Los Alamos National Laboratory

2016-11-07

The purpose of this report is to present the results of the acceptable knowledge (AK) review of oxidizers present in active waste streams, provide a technical analysis of the oxidizers, and report the results of the scoping study testing. This report will determine the fastest burning oxidizer to be used in the development of a Test Plan for Preparation and Testing of Sorbents Mixed with Oxidizer found in Transuranic Waste (DWT-TP-001). The companion report, DWT-RPT-002, Sorbent Scoping Studies, contains similar information for sorbents identified during the AK review of TRU waste streams. The results of the oxidizer and sorbent scoping studies will be used to inform the QL1 test plan. The QL1 test results will support the development of a basis of knowledge document that will evaluate oxidizing chemicals and sorbents in TRU waste and provide guidance for treatment.

All about High/Scope: Practical Summaries of High/Scope's History, Educational Approach, and Curriculum. Numbers 1-10.

Science.gov (United States)

Epstein, Ann S.

This document is comprised of 10 High/Scope fact sheets for parents, detailing the history of the High/Scope educational approach and describing its educational practice and curriculum. The major topic for each four-page fact sheet follows: (1) educational approach, including goals for young children and features of the High/Scope approach to…

The capabilities and scope-of-practice requirements of advanced life support practitioners undertaking critical care transfers: A Delphi study

Directory of Open Access Journals (Sweden)

Monique Venter

2016-11-01

Full Text Available Background. Critical care transfers (CCT refer to the high level of care given during transport (via ambulance, helicopter or fixed-wing aircraft of patients who are of high acuity. In South Africa (SA, advanced life support (ALS paramedics undertake CCTs. The scope of ALS in SA has no extended protocol regarding procedures or medications in terms of dealing with these CCTs. Aim. The aim of this study was to obtain the opinions of several experts in fields pertaining to critical care and transport and to gain consensus on the skills and scope-of-practice requirements of paramedics undertaking CCTs in the SA setting. Methods. A modified Delphi study consisting of three rounds was undertaken using an online survey platform. A heterogeneous sample (n=7, consisting of specialists in the fields of anaesthesiology, emergency medicine, internal medicine, critical care, critical care transport and paediatrics, was asked to indicate whether, in their opinion, selected procedures and medications were needed within the scope of practice of paramedics undertaking CCTs. Results. After three rounds, consensus was obtained in 70% (57/81 of procedures and medications. Many of these items are not currently within the scope of paramedics’ training. The panel felt that paramedics undertaking these transfers should have additional postgraduate training that is specific to critical care. Conclusion. Major discrepancies exist between the current scope of paramedic practice and the suggested required scope of practice for CCTs. An extended scope of practice and additional training should be considered for these practitioners.

Scope of practice review: providers for triage and assessment of spine-related disorders

Directory of Open Access Journals (Sweden)

Boakye O

2016-05-01

Full Text Available Omenaa Boakye,1 Arden Birney,1 Esther Suter,1 Leah Adeline Phillips,2 Victoria YM Suen3 1Workforce Research and Evaluation, Alberta Health Services, Calgary, 2College of Licensed Practical Nurses of Alberta, Edmonton, 3Addiction and Mental Health SCN, Alberta Health Services, Edmonton, AB, Canada Purpose: This study explored which health care providers could be involved in centralized intake for patients with nonspecific low back pain to enhance access, continuity, and appropriateness of care. Methods: We reviewed the scope of practice regulations for a range of health care providers. We also conducted telephone interviews with 17 individuals representing ten provincial colleges and regulatory bodies to further understand providers' legislated scopes of practice. Activities relevant to triaging and assessing patients with low back pain were mapped against professionals' scope of practice. Results: Family physicians and nurse practitioners have the most comprehensive scopes and can complete all restricted activities for spine assessment and triage, while the scope of registered nurses and licensed practical nurses are progressively narrower. Chiropractors, occupational therapists, physiotherapists, and athletic therapists are considered experts in musculoskeletal assessments and appear best suited for musculoskeletal specific assessment and triage. Other providers may play a complementary role depending on the individual patient needs. Conclusion: These findings indicate that an interprofessional assessment and triage team that includes allied health professionals would be a feasible option to create a centralized intake model. Implementation of such teams would require removing barriers that currently prevent providers from delivering on their full scope of practice. Keywords: scope of practice review, low back pain, integrated service model, centralized intake, interprofessional team

SCoPE: an efficient method of Cosmological Parameter Estimation

International Nuclear Information System (INIS)

Das, Santanu; Souradeep, Tarun

2014-01-01

Markov Chain Monte Carlo (MCMC) sampler is widely used for cosmological parameter estimation from CMB and other data. However, due to the intrinsic serial nature of the MCMC sampler, convergence is often very slow. Here we present a fast and independently written Monte Carlo method for cosmological parameter estimation named as Slick Cosmological Parameter Estimator (SCoPE), that employs delayed rejection to increase the acceptance rate of a chain, and pre-fetching that helps an individual chain to run on parallel CPUs. An inter-chain covariance update is also incorporated to prevent clustering of the chains allowing faster and better mixing of the chains. We use an adaptive method for covariance calculation to calculate and update the covariance automatically as the chains progress. Our analysis shows that the acceptance probability of each step in SCoPE is more than 95% and the convergence of the chains are faster. Using SCoPE, we carry out some cosmological parameter estimations with different cosmological models using WMAP-9 and Planck results. One of the current research interests in cosmology is quantifying the nature of dark energy. We analyze the cosmological parameters from two illustrative commonly used parameterisations of dark energy models. We also asses primordial helium fraction in the universe can be constrained by the present CMB data from WMAP-9 and Planck. The results from our MCMC analysis on the one hand helps us to understand the workability of the SCoPE better, on the other hand it provides a completely independent estimation of cosmological parameters from WMAP-9 and Planck data

The High Scope Approach To Early Learning

OpenAIRE

French, Geraldine

2012-01-01

Learning Objectives: After studying this chapter the reader should be able to: • Describe the historical origins, the longitudinal research, and the theoretical underpinnings of the HighScope approach. • Identify the teaching strategies adopted by HighScope educators. • Appreciate the curriculum content. • Understand the HighScope approach to the assessment of children’s learning. • Consider some criticisms of the HighScope research and approach to early learning. This ...

Community participation in Health Impact Assessment. A scoping review of the literature

NARCIS (Netherlands)

Broeder, den Lea; Uiters, Ellen; Have, ten Wim; Wagemakers, Annemarie; Schuit, Albertine Jantine

2017-01-01

Currently, the engagement of local communities in Health Impact Assessment is becoming more and more important. A scoping review was performed to take stock of visions, methods and experiences in this field. A combined Scopus and Medline search yielded 100 articles in scientific journals. The

Community participation in Health Impact Assessment. A scoping review of the literature

NARCIS (Netherlands)

den Broeder, Lea; Uiters, Ellen; ten Have, Wim; Wagemakers, Annemarie; Schuit, Albertine Jantine

2017-01-01

Currently, the engagement of local communities in Health Impact Assessment is becoming more and more important. A scoping review was performed to take stock of visions, methods and experiences in this field. A combined Scopus and Medline search yielded 100 articles in scientific journals. The final

40 CFR 725.1000 - Scope.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Scope. 725.1000 Section 725.1000 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT REPORTING....1000 Scope. This subpart identifies uses of microorganisms which EPA has determined to be significant...

47 CFR 1.1601 - Scope.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Scope. 1.1601 Section 1.1601 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE Random Selection Procedures for Mass Media Services General Procedures § 1.1601 Scope. The provisions of this subpart, and the provisions...

47 CFR 27.801 - Scope.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Scope. 27.801 Section 27.801 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES 1.4 GHz Band § 27.801 Scope. This subpart sets out the regulations governing service in...

5 CFR 2634.801 - Scope.

Science.gov (United States)

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Scope. 2634.801 Section 2634.801 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS EXECUTIVE BRANCH FINANCIAL DISCLOSURE, QUALIFIED TRUSTS, AND CERTIFICATES OF DIVESTITURE Ethics Agreements § 2634.801 Scope. This subpart applies...

5 CFR 890.1001 - Scope and purpose.

Science.gov (United States)

2010-01-01

... Providers General Provisions and Definitions § 890.1001 Scope and purpose. (a) Scope. This subpart... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Scope and purpose. 890.1001 Section 890... certain violations. The sanctions include debarment, suspension, civil monetary penalties, and financial...

The fuel cycle scoping system

International Nuclear Information System (INIS)

Dooley, G.D.; Malone, J.P.

1986-01-01

The Fuel Cycle Scoping System (FCSS) was created to fill the need for a scoping tool which provides the utilities with the ability to quickly evaluate alternative fuel management strategies, tails assay choices, fuel fabrication quotes, fuel financing alternatives, fuel cycle schedules, and other fuel cycle perturbations. The FCSS was specifically designed for PC's that support dBASE-III(TM), a relational data base software system by Ashton-Tate. However, knowledge of dBASE-III is not necessary in order to utilize the FCSS. The FCSS is menu driven and can be utilized as a teaching tool as well as a scoping tool

Validation of AEGIS/SCOPE2 system through actual core follow calculations with irregular operational conditions

International Nuclear Information System (INIS)

Tabuchi, M.; Tatsumi, M.; Ohoka, Y.; Nagano, H.; Ishizaki, K.

2017-01-01

This paper describes overview of AEGIS/SCOPE2 system, an advanced in-core fuel management system for pressurized water reactors, and its validation results of actual core follow calculations including irregular operational conditions. AEGIS and SCOPE2 codes adopt more detailed and accurate calculation models compared to the current core design codes while computational cost is minimized with various techniques on numerical and computational algorithms. Verification and validation of AEGIS/SCOPE2 has been intensively performed to confirm validity of the system. As a part of the validation, core follow calculations have been carried out mainly for typical operational conditions. After the Fukushima Daiichi nuclear power plant accident, however, all the nuclear reactors in Japan suffered from long suspension and irregular operational conditions. In such situations, measured data in the restart and operation of the reactors should be good examinations for validation of the codes. Therefore, core follow calculations were carried out with AEGIS/SCOPE2 for various cases including zero power reactor physics tests with irregular operational conditions. Comparisons between measured data and predictions by AEGIS/SCOPE2 revealed the validity and robustness of the system. (author)

Radiophotoluminescence light scope for high-dose dosimetry

International Nuclear Information System (INIS)

Sato, Fuminobu; Zushi, Naoki; Sakiyama, Tomoki; Kato, Yushi; Murata, Isao; Shimizu, Kikuo; Yamamoto, Takayoshi; Iida, Toshiyuki

2015-01-01

A radiophotoluminescence (RPL) light scope is a remote-sensing technique for measuring in situ the radiation dose in an RPL detector placed at a distance. The RPL light scope is mainly composed of an ultraviolet (UV) pulse laser, telescopic lenses, a photomultiplier tube, and camera modules. In a performance test, some RPL detectors were placed at distances up to 30 m and were illuminated with a pulsed UV laser beam. The photoluminescence responses of the RPL detectors were analyzed using this scope. Their radiation doses were determined from the amplitude of the given component of the photoluminescence responses. The RPL readout could be repeated without fading, and its amplitude exhibited good linearity at a dose ranging from 0.1 to 60 Gy. Furthermore, a two-dimensional distribution of radiation dose was obtained by laser scanning on an RPL detector. It was confirmed that the RPL light scope was a useful remote-sensing tool for high-dose dosimetry. - Highlights: • A radiophotoluminescence (RPL) light scope was developed for high-dose dosimetry. • The RPL light scope has high sensitivity and accuracy in high-dose dosimetry. • Two-dimensional radiation dose distribution was obtained by the RPL light scope.

Family Wellbeing of Individuals with Autism Spectrum Disorder: A Scoping Review

Science.gov (United States)

Tint, Ami; Weiss, Jonathan A.

2016-01-01

Families play an important role in supporting individuals with autism spectrum disorder across the lifespan. Indicators of family wellbeing can help to establish benchmarks for service provision and evaluation; however, a critical first step is a clear understanding of the construct in question. The purpose of the current scoping review was to (a)…

17 CFR 39.1 - Scope.

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Scope. 39.1 Section 39.1 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION DERIVATIVES CLEARING ORGANIZATIONS § 39.1 Scope. The provisions of this part apply to any derivatives clearing organization as defined...

Subject categories and scope descriptions

International Nuclear Information System (INIS)

2002-01-01

This document is one in a series of publications known as the ETDE/INIS Joint Reference Series. It defines the subject categories and provides the scope descriptions to be used for categorization of the nuclear literature for the preparation of INIS and ETDE input by national and regional centres. Together with the other volumes of the INIS Reference Series it defines the rules, standards and practices and provides the authorities to be used in the International Nuclear Information System and ETDE. A complete list of the volumes published in the INIS Reference Series may be found on the inside front cover of this publication. This INIS/ETDE Reference Series document is intended to serve two purposes: to define the subject scope of the International Nuclear Information System (INIS) and the Energy Technology Data Exchange (ETDE) and to define the subject classification scheme of INIS and ETDE. It is thus the guide to the inputting centres in determining which items of literature should be reported, and in determining where the full bibliographic entry and abstract of each item should be included in INIS or ETDE database. Each category is identified by a category code consisting of three alphanumeric characters. A scope description is given for each subject category. The scope of INIS is the sum of the scopes of all the categories. With most categories cross references are provided to other categories where appropriate. Cross references should be of assistance in finding the appropriate category; in fact, by indicating topics that are excluded from the category in question, the cross references help to clarify and define the scope of the category to which they are appended. A Subject Index is included as an aid to subject classifiers, but it is only an aid and not a means for subject classification. It facilitates the use of this document, but is no substitute for the description of the scope of the subject categories

IDC Reengineering Phase 2 Project Scope.

Energy Technology Data Exchange (ETDEWEB)

Harris, James M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2015-02-01

This report provides a brief description of the scope of the IDC Reengineering Phase 2 project. It describes the goals and objectives of reengineering, the system definition, and the technical scope of the system. REVISIONS Version Date Author/Team Revision Description Authorized by 1.0 9/25/2014 SNL IDC Reengineering Team Unlimited Release for I2 M. Harris 1.1 28/01/2015 IDC Reengineering Team Align with previous IDC scope document E. Tomuta.

Can optical diagnosis of small colon polyps be accurate? Comparing standard scope without narrow banding to high definition scope with narrow banding.

Science.gov (United States)

Ashktorab, Hassan; Etaati, Firoozeh; Rezaeean, Farahnaz; Nouraie, Mehdi; Paydar, Mansour; Namin, Hassan Hassanzadeh; Sanderson, Andrew; Begum, Rehana; Alkhalloufi, Kawtar; Brim, Hassan; Laiyemo, Adeyinka O

2016-07-28

To study the accuracy of using high definition (HD) scope with narrow band imaging (NBI) vs standard white light colonoscope without NBI (ST), to predict the histology of the colon polyps, particularly those high definition colonoscopes with NBI. The histopathologic diagnosis was reported by pathologists as part of routine care. Of participants in the study, 55 (37%) were male and median (interquartile range) of age was 56 (19-80). Demographic, clinical characteristics, past medical history of patients, and the data obtained by two instruments were not significantly different and two methods detected similar number of polyps. In ST scope 89% of polyps were scope (P = 0.7). The ST scope had a positive predictive value (PPV) and positive likelihood ratio (PLR) of 86% and 4.0 for adenoma compared to 74% and 2.6 for HD scope. There was a trend of higher sensitivity for HD scope (68%) compare to ST scope (53%) with almost the same specificity. The ST scope had a PPV and PLR of 38% and 1.8 for hyperplastic polyp (HPP) compared to 42% and 2.2 for HD scope. The sensitivity and specificity of two instruments for HPP diagnosis were similar. Our results indicated that HD scope was more sensitive in diagnosis of adenoma than ST scope. Clinical diagnosis of HPP with either scope is less accurate compared to adenoma. Colonoscopy diagnosis is not yet fully matched with pathologic diagnosis of colon polyp. However with the advancement of both imaging and training, it may be possible to increase the sensitivity and specificity of the scopes and hence save money for eliminating time and the cost of Immunohistochemistry/pathology.

22 CFR 309.2 - Scope.

Science.gov (United States)

2010-04-01

... thereof, or any public international organization. (2) Debts arising out of acquisitions contracts subject... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Scope. 309.2 Section 309.2 Foreign Relations PEACE CORPS DEBT COLLECTION General Provisions § 309.2 Scope. (a) Applicability of Federal Claims...

12 CFR 308.600 - Scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Scope. 308.600 Section 308.600 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Removal, Suspension, and Debarment of Accountants From Performing Audit Services § 308.600 Scope...

10 CFR 60.150 - Scope.

Science.gov (United States)

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Scope. 60.150 Section 60.150 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Quality Assurance § 60.150 Scope. As used in this part, quality assurance comprises all those planned and systematic...

10 CFR 434.101 - Scope.

Science.gov (United States)

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Scope. 434.101 Section 434.101 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY CODE FOR NEW FEDERAL COMMERCIAL AND MULTI-FAMILY HIGH RISE RESIDENTIAL BUILDINGS Administration and Enforcement-General § 434.101 Scope. 101.1 This part provides design...

30 CFR 75.823 - Scope.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Scope. 75.823 Section 75.823 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Underground High-Voltage Distribution High-Voltage Longwalls § 75.823 Scope...

15 CFR 762.1 - Scope.

Science.gov (United States)

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Scope. 762.1 Section 762.1 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS RECORDKEEPING § 762.1 Scope. In...

47 CFR 22.801 - Scope.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Scope. 22.801 Section 22.801 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES PUBLIC MOBILE SERVICES Air-Ground Radiotelephone Service § 22.801 Scope. The rules in this subpart govern the licensing and operation of air-ground...

33 CFR 25.801 - Scope.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Scope. 25.801 Section 25.801 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY GENERAL CLAIMS Pollution Removal Damage Claims § 25.801 Scope. This subpart prescribes the requirements for the administrative settlement...

EarthScope Education and Outreach: Accomplishments and Emerging Opportunities

Science.gov (United States)

Robinson, S.; Ellins, K. K.; Semken, S. C.; Arrowsmith, R.

2014-12-01

EarthScope's Education and Outreach (E&O) program aims to increase public awareness of Earth science and enhance geoscience education at the K-12 and college level. The program is distinctive among major geoscience programs in two ways. First, planning for education and public engagement occurred in tandem with planning for the science mission. Second, the NSF EarthScope program includes funding support for education and outreach. In this presentation, we highlight key examples of the program's accomplishments and identify emerging E&O opportunities. E&O efforts have been collaboratively led by the EarthScope National Office (ESNO), IRIS, UNAVCO, the EarthScope Education and Outreach Subcommittee (EEOSC) and PI-driven EarthScope projects. Efforts by the EEOSC, guided by an EarthScope Education and Outreach Implementation Plan that is periodically updated, focus EarthScope E&O. EarthScope demonstrated early success in engaging undergraduate students (and teachers) in its mission through their involvement in siting USArray across the contiguous U.S. Funded E&O programs such as TOTLE, Illinois EarthScope, CEETEP (for K-12), InTeGrate and GETSI (for undergraduates) foster use of freely available EarthScope data and research findings. The Next Generation Science Standards, which stress science and engineering practices, offer an opportunity for alignment with existing EarthScope K-12 educational resources, and the EEOSC recommends focusing efforts on this task. The EEOSC recognizes the rapidly growing use of mobile smart devices by the public and in formal classrooms, which bring new opportunities to connect with the public and students. This will capitalize on EarthScope's already prominent social media presence, an effort that developed to accomplish one of the primary goals of the EarthScope E&O Implementation Plan to "Create a high-profile public identity for EarthScope" and to "Promote science literacy and understanding of EarthScope among all audiences through

Transmit-receive eddy current probes

International Nuclear Information System (INIS)

Obrutsky, L.S.; Sullivan, S.P.; Cecco, V.S.

1997-01-01

In the last two decades, due to increased inspection demands, eddy current instrumentation has advanced from single-frequency, single-output instruments to multifrequency, computer-aided systems. This has significantly increased the scope of eddy current testing, but, unfortunately, it has also increased the cost and complexity of inspections. In addition, this approach has not always improved defect detectability or signal-to-noise. Most eddy current testing applications are still performed with impedance probes, which have well known limitations. However, recent research at AECL has led to improved eddy current inspections through the design and development of transmit-receive (T/R) probes. T/R eddy current probes, with laterally displaced transmit and receive coils, present a number of advantages over impedance probes. They have improved signal-to-noise ratio in the presence of variable lift-off compared to impedance probes. They have strong directional properties, permitting probe optimization for circumferential or axial crack detection, and possess good phase discrimination to surface defects. They can significantly increase the scope of eddy current testing permitting reliable detection and sizing of cracks in heat exchanger tubing as well as in welded areas of both ferritic and non-ferromagnetic components. This presentation will describe the operating principles of T/R probes with the help of computer-derived normalized voltage diagrams. We will discuss their directional properties and analyze the advantages of using single and multiple T/R probes over impedance probes for specific inspection cases. Current applications to surface and tube testing and some typical inspection results will be described. (author)

22 CFR 34.2 - Scope.

Science.gov (United States)

2010-04-01

... Federal agency, any foreign country or any political subdivision thereof, or any public international... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Scope. 34.2 Section 34.2 Foreign Relations DEPARTMENT OF STATE CLAIMS AND STOLEN PROPERTY DEBT COLLECTION General Provisions § 34.2 Scope. (a) Except as...

12 CFR 19.241 - Scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Scope. 19.241 Section 19.241 Banks and Banking..., and Debarment of Accountants From Performing Audit Services § 19.241 Scope. This subpart, which... their accounting firms from performing independent audit and attestation services required by section 36...

12 CFR 334.40 - Scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Scope. 334.40 Section 334.40 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY FAIR CREDIT REPORTING Duties of Furnishers of Information § 334.40 Scope. This subpart applies to a financial institution or...

10 CFR 63.141 - Scope.

Science.gov (United States)

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Scope. 63.141 Section 63.141 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Quality Assurance § 63.141 Scope. As used in this part, quality assurance comprises all those...

10 CFR 72.2 - Scope.

Science.gov (United States)

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Scope. 72.2 Section 72.2 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Provisions § 72.2 Scope. (a) Except...

6 CFR 7.2 - Scope.

Science.gov (United States)

2010-01-01

..., National Industrial Security Program, and its implementing directives. (c) This part is independent of and... 6 Domestic Security 1 2010-01-01 2010-01-01 false Scope. 7.2 Section 7.2 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CLASSIFIED NATIONAL SECURITY INFORMATION § 7.2 Scope...

19 CFR 101.0 - Scope.

Science.gov (United States)

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Scope. 101.0 Section 101.0 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY GENERAL PROVISIONS § 101.0 Scope. This part sets forth general regulations governing the authority of Customs...

Fuzzy decision analysis for project scope change management

Directory of Open Access Journals (Sweden)

Farshad Shirazi

2017-09-01

Full Text Available It is very important to manage and control projects with the consideration of the triple constraints; namely time, cost and scope. It is also extremely important to manage the scope and all the procurements needed to complete any project. During the project’s lifecycle many changes take place, either positively or negatively, which should be controlled. If the changes are not controlled we may have scope creep that has negative effect on the project. It is commonly considered a negative incident, and thus, should be kept away from the project. By considering this concept, in this paper, we discuss scope change and managing scope and fuzzy analytical hierarchy process is used in selecting the best strategy to manage scope change in projects.

Modulation of Perception or Emotion? A Scoping Review of Tinnitus Neuromodulation Using Transcranial Direct Current Stimulation.

Science.gov (United States)

Shekhawat, Giriraj Singh; Stinear, Cathy M; Searchfield, Grant D

2015-10-01

Tinnitus is the phantom perception of sound and can have negative effect on the quality of life. Transcranial direct current stimulation (tDCS) is a noninvasive neuromodulation technique, which can increase or decrease the cortical excitability in the brain region to which it is applied. tDCS has been used for tinnitus research since 2006. To investigate whether tDCS affects tinnitus perception, related emotion, or both, and the potential implications for tinnitus management. A scoping review was undertaken using the methods proposed by Arksey and O'Malley. After initial consideration of title relevance and reading abstracts, 15 studies were included in this review. The data from these studies were charted to investigate the impact of tDCS on tinnitus perception and emotions. tDCS results in transient suppression of tinnitus loudness and annoyance; however, it does not lead to long-term impact on tinnitus related emotion. Local stimulation of different sites of stimulation (left temporoparietal area, dorsolateral prefrontal cortex, and auditory cortex) might modulate tinnitus perception (loudness) and emotions differently; however, further research is needed to explore this hypothesis. This review has identified aspects of methodologies that require attention in upcoming tinnitus and tDCS trials to offer better insights. tDCS is an effective research tool for transient tinnitus neuromodulation. However, efforts should be invested in designing clinical trials using local and multiple sites of stimulation, optimized parameters, and objective outcome measures before it can be translated in to a clinical tool for tinnitus management. © The Author(s) 2015.

Effective Strategies for Achieving Scope of Practice Reform in Pennsylvania.

Science.gov (United States)

Carthon, J Margo Brooks; Wiltse Nicely, Kelly; Altares Sarik, Danielle; Fairman, Julie

2016-05-01

Current regulatory impediments prohibit advanced practice registered nurses from practicing to their full capacity. To examine the process of successful removal of scope of practice barriers in Pennsylvania under the Rx4PA legislation introduced in 2007. We used qualitative research techniques, including purposeful sampling of participants. Twelve stakeholder informed interviews were conducted between October 2013 and May 2014. Participants were closely involved with the development of the Rx4PA legislation. Thematic content analysis was performed to analyze our interviews. Interviews identified overarching themes, including the importance of leveraging years of grass roots advocacy, identifying political allies, and recognizing mutually beneficial compromises. The combination of timing, careful political maneuvering, and compromise were key to scope of practice reform in Pennsylvania and may be useful strategies for other states seeking similar practice changes. © The Author(s) 2016.

40 CFR 35.930-4 - Project scope.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Project scope. 35.930-4 Section 35.930... STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act § 35.930-4 Project scope. The grant agreement must define the scope of the project for which Federal assistance is awarded...

21 CFR 99.1 - Scope.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Scope. 99.1 Section 99.1 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL DISSEMINATION OF INFORMATION ON UNAPPROVED/NEW USES FOR MARKETED DRUGS, BIOLOGICS, AND DEVICES General Information § 99.1 Scope. (a) This...

12 CFR 7.5000 - Scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Scope. 7.5000 Section 7.5000 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY BANK ACTIVITIES AND OPERATIONS Electronic Activities § 7.5000 Scope. This subpart applies to a national bank's use of technology to deliver services and...

49 CFR 195.48 - Scope.

Science.gov (United States)

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Scope. 195.48 Section 195.48 Transportation Other... Annual, Accident, and Safety-Related Condition Reporting § 195.48 Scope. This subpart prescribes... 7000-1.1) required by § 195.49 or to provide the estimate of total miles that could affect high...

19 CFR 173.0 - Scope.

Science.gov (United States)

2010-04-01

... 19 Customs Duties 2 2010-04-01 2010-04-01 false Scope. 173.0 Section 173.0 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) ADMINISTRATIVE REVIEW IN GENERAL § 173.0 Scope. This part deals with the general authority of review, the...

30 CFR 906.1 - Scope.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Scope. 906.1 Section 906.1 Mineral Resources... OF SURFACE MINING OPERATIONS WITHIN EACH STATE COLORADO § 906.1 Scope. This part contains all rules applicable only within Colorado that have been adopted under the Surface Mining Control and Reclamation Act...

Sorbent Scoping Studies

International Nuclear Information System (INIS)

Chancellor, Christopher John

2016-01-01

The Los Alamos National Laboratory-Carlsbad Operations (LANL-CO) office was tasked by the DOE CBFO, Office of the Manager to perform a review of the acceptable knowledge (AK) to identify the oxidizers and sorbents in transuranic (TRU) waste streams, to conduct scoping studies on the oxidizers and sorbents identified in AK review to inform the Quality Level 1 (QL1) testing, and to conduct a series of QL1 tests to provide the scientific data to support a basis of knowledge document for determining the criteria for (1) accepting waste at the Waste Isolation Pilot Plant (WIPP) without treatment, (2) determining waste that will require treatment, and (3) if treatment is required, how the treatment must be performed. The purpose of this report is to present the results of the AK review of sorbents present in active waste streams, provide a technical analysis of the sorbent list, report the results of the scoping studies for the fastest-burning organic sorbent, and provide the list of organic and inorganic sorbents to be used in the development of a Test Plan for Preparation and Testing of Sorbents Mixed with Oxidizer found in Transuranic Waste (DWT-TP-001). The companion report, DWT-RPT-001, Oxidizer Scoping Studies, has similar information for oxidizers identified during the AK review of TRU waste streams. The results of the oxidizer and sorbent scoping studies will be used to inform the QL1 test plan. The QL1 test results will support the development of a basis of knowledge document that will evaluate oxidizing chemicals and sorbents in TRU waste and provide guidance for treatment.

Sorbent Scoping Studies

Energy Technology Data Exchange (ETDEWEB)

Chancellor, Christopher John [Los Alamos National Lab. (LANL), Carlsbad, NM (United States). Difficult Waste Team

2016-11-14

The Los Alamos National Laboratory–Carlsbad Operations (LANL-CO) office was tasked by the DOE CBFO, Office of the Manager to perform a review of the acceptable knowledge (AK) to identify the oxidizers and sorbents in transuranic (TRU) waste streams, to conduct scoping studies on the oxidizers and sorbents identified in AK review to inform the Quality Level 1 (QL1) testing, and to conduct a series of QL1 tests to provide the scientific data to support a basis of knowledge document for determining the criteria for (1) accepting waste at the Waste Isolation Pilot Plant (WIPP) without treatment, (2) determining waste that will require treatment, and (3) if treatment is required, how the treatment must be performed. The purpose of this report is to present the results of the AK review of sorbents present in active waste streams, provide a technical analysis of the sorbent list, report the results of the scoping studies for the fastest-burning organic sorbent, and provide the list of organic and inorganic sorbents to be used in the development of a Test Plan for Preparation and Testing of Sorbents Mixed with Oxidizer found in Transuranic Waste (DWT-TP-001). The companion report, DWT-RPT-001, Oxidizer Scoping Studies, has similar information for oxidizers identified during the AK review of TRU waste streams. The results of the oxidizer and sorbent scoping studies will be used to inform the QL1 test plan. The QL1 test results will support the development of a basis of knowledge document that will evaluate oxidizing chemicals and sorbents in TRU waste and provide guidance for treatment.

Radiosensitivity of angiogenic and mitogenic factors in human amniotic membrane

International Nuclear Information System (INIS)

Deocaris, Custer C.; De Guzman, Zenaida M.; Deocaris, Chester C.; Jacinto, Sonia D.

2003-01-01

Amniotic membrane as a temporary biological dressing remains as a beneficial and cost-effective means of treating burns in developing countries. This medical application is attributed mainly to placental structural and biochemical features that are important for maintaining proper embryonic development. Since fresh amnions are nevertheless for straightforward clinical use and for preservation, radiation-sterilization is been performed to improve the safety of this placental material. However, like any other sterilization method, gamma-radiation may induce physical and chemical changes that may influence the biological property of the material. Thus, the aim of this study is to compare the effects of various levels of radiation-sterilization protocols for human amnions on angiogenic (neovascularization) and epithelial-mitogenic activities, both of which are physiological processes fundamental to wound healing. Water-soluble extract of non-irradiated amnions demonstrates a strong stimulatory effect on both cell proliferation and angiogenesis. No change in biological activity is seen in amnions irradiated at 25 kGy, the sterilization dose used by the Philippine Nuclear Research Institute (PNRI) for the production of radiation-sterilized human amniotic membranes (RSHAM). However, it appears that amniotic angiogenic factors are more radiosensitive than its mitogenic components, evident from the depressed vascularization of the chorioallantoic membrane (CAM) exposed to 35 kGy-irradiated amnions. The dose of 35 kGy is at present the medical sterilization dose used at the Central Tissue Bank in Warsaw (Poland) for the preparation of their amnion allografts. (Authors)

21 CFR 1311.01 - Scope.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Scope. 1311.01 Section 1311.01 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE REQUIREMENTS FOR ELECTRONIC ORDERS AND PRESCRIPTIONS (Eff. 6.... For the convenience of the user, the revised text is set forth as follows: § 1311.01 Scope. This part...

21 CFR 328.1 - Scope.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Scope. 328.1 Section 328.1 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE OVER-THE-COUNTER DRUG PRODUCTS INTENDED FOR ORAL INGESTION THAT CONTAIN ALCOHOL General Provisions § 328.1 Scope...

21 CFR 54.3 - Scope.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Scope. 54.3 Section 54.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL FINANCIAL DISCLOSURE BY CLINICAL INVESTIGATORS § 54.3 Scope. The requirements in this part apply to any applicant who submits a marketing...

33 CFR 64.03 - Scope.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Scope. 64.03 Section 64.03... STRUCTURES, SUNKEN VESSELS AND OTHER OBSTRUCTIONS General § 64.03 Scope. (a) Except as provided in paragraph... jurisdiction of the United States and, on the high seas, structures owned or operated by persons subject to the...

Medication safety programs in primary care: a scoping review.

Science.gov (United States)

Khalil, Hanan; Shahid, Monica; Roughead, Libby

2017-10-01

Medication safety plays an essential role in all healthcare organizations; improving this area is paramount to quality and safety of any wider healthcare program. While several medication safety programs in the hospital setting have been described and the associated impact on patient safety evaluated, no systematic reviews have described the impact of medication safety programs in the primary care setting. A preliminary search of the literature demonstrated that no systematic reviews, meta-analysis or scoping reviews have reported on medication safety programs in primary care; instead they have focused on specific interventions such as medication reconciliation or computerized physician order entry. This scoping review sought to map the current medication safety programs used in primary care. The current scoping review sought to examine the characteristics of medication safety programs in the primary care setting and to map evidence on the outcome measures used to assess the effectiveness of medication safety programs in improving patient safety. The current review considered participants of any age and any condition using care obtained from any primary care services. We considered studies that focussed on the characteristics of medication safety programs and the outcome measures used to measure the effectiveness of these programs on patient safety in the primary care setting. The context of this review was primary care settings, primary healthcare organizations, general practitioner clinics, outpatient clinics and any other clinics that do not classify patients as inpatients. We considered all quantitative studied published in English. A three-step search strategy was utilized in this review. Data were extracted from the included studies to address the review question. The data extracted included type of medication safety program, author, country of origin, aims and purpose of the study, study population, method, comparator, context, main findings and outcome

32 CFR 651.48 - Scoping process.

Science.gov (United States)

2010-07-01

... significantly affecting the environment will go through scoping unless extenuating circumstances make it... associated environmental controversy. (4) Importance of the affected environmental parameters. (5... the affected Army organization or installation. Such integration is encouraged. (f) Scoping procedures...

Clinical reasoning in undergraduate nursing education: a scoping review

OpenAIRE

Menezes,Sáskia Sampaio Cipriano de; Corrêa,Consuelo Garcia; Silva,Rita de Cássia Gengo e; Cruz,Diná de Almeida Monteiro Lopes da

2015-01-01

Abstract OBJECTIVE This study aimed at analyzing the current state of knowledge on clinical reasoning in undergraduate nursing education. METHODS A systematic scoping review through a search strategy applied to the MEDLINE database, and an analysis of the material recovered by extracting data done by two independent reviewers. The extracted data were analyzed and synthesized in a narrative manner. RESULTS From the 1380 citations retrieved in the search, 23 were kept for review and their co...

Residential ventilation standards scoping study

Energy Technology Data Exchange (ETDEWEB)

McKone, Thomas E.; Sherman, Max H.

2003-10-01

The goals of this scoping study are to identify research needed to develop improved ventilation standards for California's Title 24 Building Energy Efficiency Standards. The 2008 Title 24 Standards are the primary target for the outcome of this research, but this scoping study is not limited to that timeframe. We prepared this scoping study to provide the California Energy Commission with broad and flexible options for developing a research plan to advance the standards. This document presents the findings of a scoping study commissioned by the Public Interest Energy Research (PIER) program of the California Energy Commission to determine what research is necessary to develop new residential ventilation requirements for California. This study is one of three companion efforts needed to complete the job of determining the ventilation needs of California residences, determining the bases for setting residential ventilation requirements, and determining appropriate ventilation technologies to meet these needs and requirements in an energy efficient manner. Rather than providing research results, this scoping study identifies important research questions along with the level of effort necessary to address these questions and the costs, risks, and benefits of pursuing alternative research questions. In approaching these questions and corresponding levels of effort, feasibility and timing were important considerations. The Commission has specified Summer 2005 as the latest date for completing this research in time to update the 2008 version of California's Energy Code (Title 24).

Development of the AuScope Australian Earth Observing System

Science.gov (United States)

Rawling, T.

2017-12-01

Advances in monitoring technology and significant investment in new national research initiatives, will provide significant new opportunities for delivery of novel geoscience data streams from across the Australian continent over the next decade. The AuScope Australian Earth Observing System (AEOS) is linking field and laboratory infrastructure across Australia to form a national sensor array focusing on the Solid Earth. As such AuScope is working with these programs to deploy observational infrastructure, including MT, passive seismic, and GNSS networks across the entire Australian Continent. Where possible the observational grid will be co-located with strategic basement drilling in areas of shallow cover and tied with national reflection seismic and sampling transects. This integrated suite of distributed earth observation and imaging sensors will provide unprecedented imaging fidelity of our crust, across all length and time scales, to fundamental and applied researchers in the earth, environmental and geospatial sciences. The AEOS will the Earth Science community's Square Kilometer Array (SKA) - a distributed telescope that looks INTO the earth rather than away from it - a 10 million SKA. The AEOS is strongly aligned with other community strategic initiatives including the UNCOVER research program as well as other National Collaborative Research Infrastructure programs such as the Terrestrial Environmental Research Network (TERN) and the Integrated Marine Observing System (IMOS) providing an interdisciplinary collaboration platform across the earth and environmental sciences. There is also very close alignment between AuScope and similar international programs such as EPOS, the USArray and EarthCube - potential collaborative linkages we are currently in the process of pursuing more fomally. The AuScope AEOS Infrastructure System is ultimately designed to enable the progressive construction, refinement and ongoing enrichment of a live, "FAIR" four

Registered nurses’ knowledge, attitude, practice and regulation regarding their scope of practice: A literature review

Directory of Open Access Journals (Sweden)

M.M. Feringa

Full Text Available Over the years, extensive task shifting and sharing has taken place in nursing. In several countries, especially Botswana and other African countries, nurses are often responsible for duties and interventions they consider to be beyond their Scope of Practice (SoP or regard as ‘non-nursing’ tasks. Issues and concerns affecting SoP may have considerable impact on the quality of care and welfare of nurses. The aim of this article is to present the results of a literature review regarding the Scope of Practice of Registered Nurses. Method: A literature search was performed, using the following internet databases EbscoHost, Nursing@Ovid and Google Scholar. ResearchGate, Science Direct, Sage and Sabinet were also consulted, as well as websites of professional organizations and the Botswana Collection at the University of Botswana Library. Articles published in English between 2000 and 2018 were reviewed. Key search concepts included: scope of practice of nurses and knowledge, attitude, practice and regulation. Findings and discussion: Knowledge of nurses regarding their SoP appears variable and attitudes are usually positive, as long as scope expansion is congruent with legislation. Literature illustrates that nurses regularly practise outside their scope, either beyond or below, whereas SoP may overlap, both intra-disciplinary as well as interdisciplinary. Although the SoP of nurses appears to be regulated in many countries, regulation often appears insufficient to meet the evolving nature of the nursing profession. Conclusion: In the current changing worldwide health arena, scoping issues remain relevant and warrant imminent attention. Keywords: Scope of practice of nurses, Knowledge, Attitude, Practice, Regulation

Scope of work for evaluating the mechanical performance of EPR first wall coatings

International Nuclear Information System (INIS)

Jones, W.B.; Van Den Avyle, J.A.

1978-01-01

An outline is presented for a proposed scope of work to evaluate the mechanical performance of candidate first wall coatings for a Tokamak-type fusion reactor. The goal of the overall program is to provide an adequate coating material and recoating process which can be manufactured by currently available vendors

On the optimal scope of negligence

NARCIS (Netherlands)

Dari-Mattiacci, G.

2005-01-01

This article studies the optimal scope of negligence, considering which of the parties’ precautionary measures should be included in the determination of negligence and which instead should be omitted. The analysis shows that the optimal scope of negligence balances the gains derived from improved

Okul Öncesi Eğitimde High Scope Modeli

OpenAIRE

Kotaman, Hüseyin

2009-01-01

Purpose of this study is to examine High Scope early childhood education system which was developed in USA. Accordingly historical reasons underlied the development of High Scope, systems’ educational theory, its’ curriculum and daily program routine, teachers’ characteristics and their responsibilities and High Scope’s evaluation system are defined. High Scope system base on Piaget’s constructivist theory. In this liberal educational system child learn through invent and const...

Synergies between renewable energy and fresh water production. Scoping study

Energy Technology Data Exchange (ETDEWEB)

Geurts, F.; Noothout, P.; Schaap, A. [Ecofys Netherlands, Utrecht (Netherlands)

2011-02-15

The IEA Implementing Agreement for Renewable Energy Technology Deployment (IEA-RETD) investigated the opportunities for coupling renewable energy systems with fresh water supply systems. The four main conclusions of the scoping study, carried out by Ecofys, are: (1) Fresh water production based on desalination technologies provide most options for synergies with renewable energy production; (2) Linking desalination to renewable sources is currently not economically viable; (3) There is a large potential for small scale (decentralised) desalination plants; (4) Current commercially-sized desalination technologies are in need of a constant operation point. Reverse osmosis and thermal membrane technologies might give future synergies as deferrable load.

Soft Tissue Repair with Easy-Accessible Autologous Newborn Placenta or Umbilical Cord Blood in Severe Malformations: A Primary Evaluation

Science.gov (United States)

2017-01-01

Disrupted organogenesis leads to permanent malformations that may require surgical correction. Autologous tissue grafts may be needed in severe lack of orthotopic tissue but include donor site morbidity. The placenta is commonly discarded after birth and has a therapeutic potential. The aim of this study was to determine if the amnion from placenta or plasma rich of growth factors (PRGF) with mononuclear cells (MNC) from umbilical cord blood (UCB), collected noninvasively, could be used as bio-constructs for autologous transplantation as an easy-accessible no cell culture-required method. Human amnion and PRGF gel were isolated and kept in culture for up to 21 days with or without small intestine submucosa (SIS). The cells in the constructs showed a robust phenotype without induced increased proliferation (Ki67) or apoptosis (caspase 3), but the constructs showed decreased integrity of the amnion-epithelial layer at the end of culture. Amnion-residing cells in the SIS constructs expressed CD73 or pan-cytokeratin, and cells in the PRGF-SIS constructs expressed CD45 and CD34. This study shows that amnion and UCB are potential sources for production of autologous grafts in the correction of congenital soft tissue defects. The constructs can be made promptly after birth with minimal handling or cell expansion needed. PMID:29403534

Soft Tissue Repair with Easy-Accessible Autologous Newborn Placenta or Umbilical Cord Blood in Severe Malformations: A Primary Evaluation

Directory of Open Access Journals (Sweden)

Åsa Ekblad

2017-01-01

Full Text Available Disrupted organogenesis leads to permanent malformations that may require surgical correction. Autologous tissue grafts may be needed in severe lack of orthotopic tissue but include donor site morbidity. The placenta is commonly discarded after birth and has a therapeutic potential. The aim of this study was to determine if the amnion from placenta or plasma rich of growth factors (PRGF with mononuclear cells (MNC from umbilical cord blood (UCB, collected noninvasively, could be used as bio-constructs for autologous transplantation as an easy-accessible no cell culture-required method. Human amnion and PRGF gel were isolated and kept in culture for up to 21 days with or without small intestine submucosa (SIS. The cells in the constructs showed a robust phenotype without induced increased proliferation (Ki67 or apoptosis (caspase 3, but the constructs showed decreased integrity of the amnion-epithelial layer at the end of culture. Amnion-residing cells in the SIS constructs expressed CD73 or pan-cytokeratin, and cells in the PRGF-SIS constructs expressed CD45 and CD34. This study shows that amnion and UCB are potential sources for production of autologous grafts in the correction of congenital soft tissue defects. The constructs can be made promptly after birth with minimal handling or cell expansion needed.

Cross-linguistic scope ambiguity: When two systems meet

Directory of Open Access Journals (Sweden)

Gregory Scontras

2017-04-01

Full Text Available Accurately recognizing and resolving ambiguity is a hallmark of linguistic ability. English is a language with scope ambiguities in doubly-quantified sentences like 'A shark ate every pirate'; this sentence can either describe a scenario with a single shark eating all of the pirates, or a scenario with many sharks—a potentially-different one eating each pirate. In Mandarin Chinese, the corresponding sentence is unambiguous, as it can only describe the single-shark scenario. We present experimental evidence to this effect, comparing native speakers of English with native speakers of Mandarin in their interpretations of doubly-quantified sentences. Having demonstrated the difference between these two languages in their ability for inverse scope interpretations, we then probe the robustness of the grammar of scope by extending our experiments to English-dominant adult heritage speakers of Mandarin. Like native speakers of Mandarin, heritage Mandarin speakers lack inverse scope in Mandarin. Crucially, these speakers also lack inverse scope in English, their dominant language in adulthood. We interpret these results as evidence for the pressure to simplify the grammar of scope, decreasing ambiguity when possible. In other words, when two systems meet—as in the case of heritage speakers—the simpler system prevails. This article is part of the special collection: Quantifier Scope

Sustainable Tourism: its Interpretation and Operational Scope

Directory of Open Access Journals (Sweden)

Marcela Bertoni

2008-01-01

Full Text Available The application of sustainability principles in tourism is an essential reference for the processes of development and promotion of potential destinations and for the restructuring  of current ones. However, there is a dichotomy between the wide spread of the concept of sustainable tourism and the limitations of the reached progress. This paper intends to encourage a theoretical discussion to examine the definitions of sustainable tourism from diverse approaches, viewpoints and scopes, and to analyze the relevant aspects of its operability, related to the integration of massive and sustainable tourism and to the implications of sustainable development, politics and social participation.

A multicenter, randomized, controlled clinical trial evaluating the use of dehydrated human amnion/chorion membrane allografts and multilayer compression therapy vs. multilayer compression therapy alone in the treatment of venous leg ulcers.

Science.gov (United States)

Serena, Thomas E; Carter, Marissa J; Le, Lam T; Sabo, Matthew J; DiMarco, Daniel T

2014-01-01

Venous leg ulcers produce significant clinical and economic burdens on society and often require advanced wound therapy. The purpose of this multicenter, randomized, controlled study is to evaluate the safety and efficacy of one or two applications of dehydrated human amnion/chorion membrane allograft and multilayer compression therapy vs. multilayer compression therapy alone in the treatment of venous leg ulcers. The primary study outcome was the proportion of patients achieving 40% wound closure at 4 weeks. Of the 84 participants enrolled, 53 were randomized to receive allograft and 31 were randomized to the control group of multilayer compression therapy alone. At 4 weeks, 62% in the allograft group and 32% in the control group showed a greater than 40% wound closure (p = 0.005), thus showing a significant difference between the allograft-treated groups and the multilayer compression therapy alone group at the 4-week surrogate endpoint. After 4 weeks, wounds treated with allograft had reduced in size a mean of 48.1% compared with 19.0% for controls. Venous leg ulcers treated with allograft had a significant improvement in healing at 4 weeks compared with multilayer compression therapy alone. © 2014 by the Wound Healing Society.

41 CFR 128-1.8000 - Scope.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Scope. 128-1.8000 Section 128-1.8000 Public Contracts and Property Management Federal Property Management Regulations System (Continued) DEPARTMENT OF JUSTICE 1-INTRODUCTION 1.80-Seismic Safety Program § 128-1.8000 Scope. This subpart...

76 FR 51022 - Juneau Hydropower, Inc.; Notice of Scoping Meeting and Site Visit and Soliciting Scoping Comments...

Science.gov (United States)

2011-08-17

... Hydropower, Inc.; Notice of Scoping Meeting and Site Visit and Soliciting Scoping Comments for an Applicant...: Alternative Licensing Process. b. Project No.: 13563-001. c. Applicant: Juneau Hydropower, Inc. d. Name of... Mitchell, Business Manager, Juneau Hydropower, Inc., P.O. Box 22775, Juneau, AK 99802; 907-789-2775, e...

Physical Activity Research in Intellectual Disability: A Scoping Review Using the Behavioral Epidemiological Framework

Science.gov (United States)

Pitchford, E. Andrew; Dixon-Ibarra, Alicia; Hauck, Janet L.

2018-01-01

Through a scoping review, the current state of physical activity research in people with intellectual disability was examined. A search of publications between 2000 and 2014 retrieved 362 articles that met inclusion criteria. Eligible studies were coded according to the Behavioral Epidemiological Framework. Of the articles identified, 48% examined…

Availability of caregiver-friendly workplace policies (CFWPs): an international scoping review.

Science.gov (United States)

Ireson, Rachelle; Sethi, Bharati; Williams, Allison

2018-01-01

Little research has been done to summarise: what is currently available to caregiver-employees (CEs), what types of employers are offering caregiver-friendly workplace policies (CFWPs), and the characteristics of employers offering CFWPs. The purpose of this scoping review was to explore the availability of CFWPs within workplaces on an international scale while being observant of how gender is implicated in care-giving. This paper followed the Arksey & O'Malley (2005) methodology for conducting scoping reviews. The authors applied an iterative method of determining study search strings, study inclusion and data extraction, and qualitative thematic analysis of the search results. Searches were performed in both the academic and grey literature, published between 1994 and 2014. A total of 701 articles were found. Seventy (n = 70) articles met all inclusion criteria and were included in this review. Four main qualitative themes were identified: (i) Diversity and Inclusiveness, (ii) Motivation, (iii) Accessibility, and (iv) Workplace Culture. Policy recommendations are discussed. This scoping review narrows the gap in the literature with respect to determining: (i) the workplaces which offer CFWPs, (ii) the sectors of the labour force shown to be supportive and (iii) the most frequently offered CFWPs. © 2016 The Authors. Health and Social Care in the Community Published by John Wiley & Sons Ltd.

ScienceScope: Aerospace

CSIR Research Space (South Africa)

CSIR

2006-12-01

Full Text Available In this edition of ScienceScope, innovations in and around aerodynamics research and development is explored. The publication explores activities in environmentally friendly aerospace technologies to enhance the aviation industry....

Massage therapy: understanding the mechanisms of action on blood pressure. A scoping review.

Science.gov (United States)

Nelson, Nicole L

2015-10-01

Massage therapy (MT) has shown potential in reducing blood pressure (BP); however, the psychophysiological pathways and structures involved in this outcome are unclear. The aims of this scoping review were twofold. (1) To summarize the current knowledge of the mechanisms of action of MT on BP. (2) To highlight the research gaps and challenges that researchers must overcome to further elucidate how MT attenuates BP. A scoping review was conducted to examine the evidence regarding the mechanisms of action of MT on BP. This review included the thematic analysis of 27 publications that considered the influence of MT on BP. Based on this analysis, six potential BP mediating pathways were identified Current theories suggest that MT exerts sympatholytic effects through physiologic and psychological mechanisms, improves hypothalamus-pituitary-adrenocortical axis function, and increases in blood flow, which, in turn, may improve endothelial function. Future study is needed, using more scientifically rigorous methodology, to fully elucidate the mechanism of action of MT. Copyright © 2015 American Society of Hypertension. Published by Elsevier Inc. All rights reserved.

Prioritising Project Scope Definition Elements in Public Building Projects

Directory of Open Access Journals (Sweden)

Mohammed K Fageha

2014-09-01

Full Text Available A complete definition of the scope of a project upfront during early stages ensures smooth and successful implementation during the project execution. This research identifies and prioritises project scope definition elements for public buildings in Saudi Arabia. Elements that could significantly contribute to complete project scope definition package at pre-project planning stage are identified and their interrelationship determined and prioritised. Using the Project Definition Rating Index (PDRI as a basis, the study uses analytical network process (ANP technique based on data obtained from project managers who have been involved in public sector projects in Saudi Arabia. Data collection and analysis was conducted in three steps. The first step involved identification of scope definition elements while the second involved an investigation into interrelationships among the elements. In the third step, ANP was used to determine the weight of the elements’ importance in terms of contribution to project scope definition completeness. Finally, Pareto analysis was used to prioritise and assess the distribution pattern of the elements. The outcome from this research is the prioritisation of project scope definition elements for public building projects in Saudi Arabia. The prioritised list developed indicates the importance of project scope definition elements. It should help project management teams identify elements to consider when evaluating project scope definition for completeness at the pre-project planning stage. Keywords: Project scope definition, pre-project planning, prioritising, public building projects, Saudi Arabia, Analytical Network Process (ANP

The Impact of Consumer Knowledge Bias on Narrow-Scope Trust, Broad-Scope Trust, and Relationship Satisfaction

DEFF Research Database (Denmark)

Hansen, Torben; Grønholdt, Lars; Josiassen, Alexander

2016-01-01

This study investigates how consumer knowledge bias - defined as knowledge over/underconfidence (O/U) - influences two types of trust (broad-scope trust and narrow-scope trust) and consumer relationship satisfaction. Based on a survey comprising 756 mutual fund investors, the contribution...... of this study to the marketing literature is twofold. First, taking a marketing relationship approach this study suggests and demonstrates that knowledge O/U positively influences relationship satisfaction and narrow-scope trust such that the more knowledge O/U a customer becomes, the higher/lower the level...... is low compared to high. Notably, the study findings strongly suggest that marketing managers should carry out their relationship satisfaction and trust improvement efforts relative to the combination of customers‟ subjective and objective knowledge....

Context, Rational, Scope and Objectives of the Meeting

International Nuclear Information System (INIS)

Monti, S.

2013-01-01

Scope and objectives of the technical meeting: • Presenting and exchanging information about existing and planned experimental facilities in support of the development of innovative fast neutron systems. • Facilitate the creation of a catalogue of existing and planned experimental facilities that are currently being operated or developed within national or international fast reactor programmes. • Identify experimental facilities which could provide experimental data in particular for V&V&Q of simulation tools for the design and the safety analysis of innovative fast neutron systems. • Discuss needs and propose new experimental activities to be carried out at international level

Scoping of flood hazard mapping needs for Kennebec County, Maine

Science.gov (United States)

Dudley, Robert W.; Schalk, Charles W.

2006-01-01

. However, in the ensuing 20-30 years, development has occurred in many of the watersheds, and the characteristics of the watersheds have changed with time. Therefore, many of the older studies may not depict current conditions nor accurately estimate risk in terms of flood heights. The following is the scope of work as defined in the FEMA/USGS Statement of Work: Task 1: Collect data from a variety of sources including community surveys, other Federal and State Agencies, National Flood Insurance Program (NFIP) State Coordinators, Community Assistance Visits (CAVs) and FEMA archives. Lists of mapping needs will be obtained from the MNUSS database, community surveys, and CAVs, if available. FEMA archives will be inventoried for effective FIRM panels, FIS reports, and other flood-hazard data or existing study data. Best available base map information, topographic data, flood-hazard data, and hydrologic and hydraulic data will be identified. Data from the Maine Floodplain Management Program database also will be utilized. Task 2: Contact communities in Kennebec County to notify them that FEMA and the State have selected them for a map update, and that a project scope will be developed with their input. Topics to be reviewed with the communities include (1) Purpose of the Flood Map Project (for example, the update needs that have prompted the map update); (2) The community's mapping needs; (3) The community's available mapping, hydrologic, hydraulic, and flooding information; (4) target schedule for completing the project; and (5) The community's engineering, planning, and geographic information system (GIS) capabilities. On the basis of the collected information from Task 1 and community contacts/meetings in Task 2, the USGS will develop a Draft Project Scope for the identified mapping needs of the communities in Kennebec County. The following items will be addressed in the Draft Project Scope: review of available information, determine if and how e

Scoping of flood hazard mapping needs for Somerset County, Maine

Science.gov (United States)

Dudley, Robert W.; Schalk, Charles W.

2006-01-01

s. However, in the ensuing 20-30 years, development has occurred in many of the watersheds, and the characteristics of the watersheds have changed with time. Therefore, many of the older studies may not depict current conditions nor accurately estimate risk in terms of flood heights. The following is the scope of work as defined in the FEMA/USGS Statement of Work: Task 1: Collect data from a variety of sources including community surveys, other Federal and State Agencies, National Flood Insurance Program (NFIP) State Coordinators, Community Assistance Visits (CAVs) and FEMA archives. Lists of mapping needs will be obtained from the MNUSS database, community surveys, and CAVs, if available. FEMA archives will be inventoried for effective FIRM panels, FIS reports, and other flood-hazard data or existing study data. Best available base map information, topographic data, flood-hazard data, and hydrologic and hydraulic data will be identified. Data from the Maine Floodplain Management Program database also will be utilized. Task 2: Contact communities in Somerset County to notify them that FEMA and the State have selected them for a map update, and that a project scope will be developed with their input. Topics to be reviewed with the communities include (1) Purpose of the Flood Map Project (for example, the update needs that have prompted the map update); (2) The community's mapping needs; (3) The community's available mapping, hydrologic, hydraulic, and flooding information; (4) target schedule for completing the project; and (5) The community's engineering, planning, and geographic information system (GIS) capabilities. On the basis of the collected information from Task 1 and community contacts/meetings in Task 2, the USGS will develop a Draft Project Scope for the identified mapping needs of the communities in Somerset County. The following items will be addressed in the Draft Project Scope: review of available information, determine if and ho

Knowledge Syntheses in Medical Education: Demystifying Scoping Reviews.

Science.gov (United States)

Thomas, Aliki; Lubarsky, Stuart; Durning, Steven J; Young, Meredith E

2017-02-01

An unprecedented rise in health professions education (HPE) research has led to increasing attention and interest in knowledge syntheses. There are many different types of knowledge syntheses in common use, including systematic reviews, meta-ethnography, rapid reviews, narrative reviews, and realist reviews. In this Perspective, the authors examine the nature, purpose, value, and appropriate use of one particular method: scoping reviews. Scoping reviews are iterative and flexible and can serve multiple main purposes: to examine the extent, range, and nature of research activity in a given field; to determine the value and appropriateness of undertaking a full systematic review; to summarize and disseminate research findings; and to identify research gaps in the existing literature. Despite the advantages of this methodology, there are concerns that it is a less rigorous and defensible means to synthesize HPE literature. Drawing from published research and from their collective experience with this methodology, the authors present a brief description of scoping reviews, explore the advantages and disadvantages of scoping reviews in the context of HPE, and offer lessons learned and suggestions for colleagues who are considering conducting scoping reviews. Examples of published scoping reviews are provided to illustrate the steps involved in the methodology.

Making Patent Scopes Exceed the Technological Scopes of Scientific Inventions

DEFF Research Database (Denmark)

Beukel, Karin

This paper presents the results of a grounded theory study of the transformation of scientific discoveries into patented inventions. Using an algebraic interpretive approach, the narratives collected during interviews are analyzed as Bayesian inferences and the developed theory is tested. The fin...... for searching in new directions for solutions if challenges of exploitation with regard to the scientific invention arise.......This paper presents the results of a grounded theory study of the transformation of scientific discoveries into patented inventions. Using an algebraic interpretive approach, the narratives collected during interviews are analyzed as Bayesian inferences and the developed theory is tested....... The findings recast the relationship between science and patents as a process in which the way the transformation of the scientific invention is handled has an effect on the breadth of the patent scope. Unleashing patent scope surplus is dependent on processes related to abstraction and cognitive variety...

Scoping the role and education needs of practice nurses in London.

Science.gov (United States)

Procter, Susan; Griffiths, Lauren; Fanning, Agnes; Wallman, Lizzie; Loveday, Heather P

2017-07-01

Aims To identify education priorities for practice nursing across eight London Clinical Commissioning Groups (CCGs); to identify the education, training, development and support needs of practice nurses in undertaking current and future roles. The education needs of practice nurses have long been recognised but their employment status means that accessing education requires the support of their GP employer. This study scopes the educational requirements of the practice nurse workforce and working with educational providers and commissioners describes a coherent educational pathway for practice nurses. A survey of practice nurses to scope their educational attainment needs was undertaken. Focus groups were carried out which identified the education, training, development and support needs of practice nurses to fulfil current and future roles. Findings A total of 272 respondents completed the survey. Practice nurses took part in three focus groups (n=34) and one workshop (n=39). Findings from this research indicate a practice nurse workforce which lacked career progression, role autonomy or a coherent educational framework. Practice nurses recognised the strength of their role in building relationship-centred care with patients over an extended period of time. They valued this aspect of their role and would welcome opportunities to develop this to benefit patients. This paper demonstrates an appetite for more advanced education among practice nurses, a leadership role by the CCGs in working across the whole system to address the education needs of practice nurses, and a willingness on the part of National Health Service education commissioners to commission education which meets the education needs of the practice nurse workforce. Evidence is still required, however, to inform the scope of the practice nurse role within an integrated system of care and to identify the impact of practice nursing on improving health outcomes and care of local populations.

A scoping review of crisis teams managing dementia in older people.

Science.gov (United States)

Streater, Amy; Coleston-Shields, Donna Maria; Yates, Jennifer; Stanyon, Miriam; Orrell, Martin

2017-01-01

Research on crisis teams for older adults with dementia is limited. This scoping review aimed to 1) conduct a systematic literature review reporting on the effectiveness of crisis interventions for older people with dementia and 2) conduct a scoping survey with dementia crisis teams mapping services across England to understand operational procedures and identify what is currently occurring in practice. For the systematic literature review, included studies were graded using the Critical Appraisal Skills Programme checklist. For the scoping survey, Trusts across England were contacted and relevant services were identified that work with people with dementia experiencing a mental health crisis. The systematic literature review demonstrated limited evidence in support of crisis teams reducing the rate of hospital admissions, and despite the increase in number of studies, methodological limitations remain. For the scoping review, only half (51.8%) of the teams had a care pathway to manage crises and the primary need for referral was behavioral or psychological factors. Evidence in the literature for the effectiveness of crisis teams for older adults with dementia remains limited. Being mainly cohort designs can make it difficult to evaluate the effectiveness of the intervention. In practice, it appears that the pathway for care managing crisis for people with dementia varies widely across services in England. There was a wide range of names given to the provision of teams managing crisis for people with dementia, which may reflect the differences in the setup and procedures of the service. To provide evidence on crisis intervention teams, a comprehensive protocol is required to deliver a standardized care pathway and measurable intervention as part of a large-scale evaluation of effectiveness.

Role of government in public health: Current scenario in India and future scope

Directory of Open Access Journals (Sweden)

Subitha Lakshminarayanan

2011-01-01

Full Text Available The new agenda for Public Health in India includes the epidemiological transition, demographical transition, environmental changes and social determinants of health. Based on the principles outlined at Alma-Ata in 1978, there is an urgent call for revitalizing primary health care in order to meet these challenges. The role of the government in influencing population health is not limited within the health sector but also by various sectors outside the health systems. This article is a literature review of the existing government machinery for public health needs in India, its success, limitations and future scope. Health system strengthening, human resource development and capacity building and regulation in public health are important areas within the health sector. Contribution to health of a population also derives from social determinants of health like living conditions, nutrition, safe drinking water, sanitation, education, early child development and social security measures. Population stabilization, gender mainstreaming and empowerment, reducing the impact of climate change and disasters on health, improving community participation and governance issues are other important areas for action. Making public health a shared value across the various sectors is a politically challenging strategy, but such collective action is crucial.

What are scoping studies? A review of the nursing literature.

Science.gov (United States)

Davis, Kathy; Drey, Nick; Gould, Dinah

2009-10-01

Scoping studies are increasingly undertaken as distinct activities. The interpretation, methodology and expectations of scoping are highly variable. This suggests that conceptually, scoping is a poorly defined ambiguous term. The distinction between scoping as an integral preliminary process in the development of a research proposal or a formative, methodologically rigorous activity in its own right has not been extensively examined. The aim of this review is to explore the nature and status of scoping studies within the nursing literature and develop a working definition to ensure consistency in the future use of scoping as a research related activity. This paper follows an interpretative scoping review methodology. An explicit systematic search strategy included literary and web-based key word searches and advice from key researchers. Electronic sources included bibliographic and national research register databases and a general browser. The scoping studies varied widely in terms of intent, procedural and methodological rigor. An atheoretical stance was common although explicit conceptual clarification and development of a topic was limited. Four different levels of inquiry ranging from preliminary descriptive surveys to more substantive conceptual approaches were conceptualised. These levels reflected differing dimensional distinctions in which some activities constitute research whereas in others the scoping activities appear to fall outside the remit of research. Reconnaissance emerges as a common synthesising construct to explain the purpose of scoping. Scoping studies in relation to nursing are embryonic and continue to evolve. Its main strengths lie in its ability to extract the essence of a diverse body of evidence giving it meaning and significance that is both developmental and intellectually creative. As with other approaches to research and evidence synthesis a more standardized approach is required.

10 CFR 600.500 - Purpose and scope.

Science.gov (United States)

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Purpose and scope. 600.500 Section 600.500 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES Eligibility Determination for Certain Financial Assistance Programs-General Statement of Policy § 600.500 Purpose and scope...

5 CFR 179.301 - Scope of regulations.

Science.gov (United States)

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Scope of regulations. 179.301 Section 179.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS CLAIMS COLLECTION STANDARDS Administrative Offset § 179.301 Scope of regulations. These regulations apply to the...

Hardware Support for Safety-critical Java Scope Checks

DEFF Research Database (Denmark)

Rios Rivas, Juan Ricardo; Schoeberl, Martin

2012-01-01

Memory management in Safety-Critical Java (SCJ) is based on time bounded, non garbage collected scoped memory regions used to store temporary objects. Scoped memory regions may have different life times during the execution of a program and hence, to avoid leaving dangling pointers, it is necessary...... in terms of execution time for applications where cross-scope references are frequent. Our proposal was implemented and tested on the Java Optimized Processor (JOP)....

Attentional states influence early neural responses associated with motivational processes: local vs. global attentional scope and N1 amplitude to appetitive stimuli.

Science.gov (United States)

Gable, Philip A; Harmon-Jones, Eddie

2011-05-01

Positive affects vary in the degree with which they are associated with approach motivation, the drive to approach an object or a goal. High approach-motivated positive affects cause a narrowing of attention, whereas low approach-motivated positive affects causes a broadening of attention. The current study was designed to extend this work by examining whether the relationship between motivation and attentional bias was bi-directional. Specifically, the experiment investigated whether a manipulated local attentional scope would cause greater approach motivational processing than a global attentional scope as measured by neural processes as early as 100 ms. As compared to a global attentional scope, a local attentional scope caused greater neural processing associated with approach motivation as measured by the N1 to appetitive pictures. Copyright © 2011 Elsevier B.V. All rights reserved.

Observational therapeutics: Scope, challenges, and organization.

Science.gov (United States)

Vaidya, Rama

2011-10-01

The importance of Observational Therapeutics in the progress of medicine has been neglected in the current era of the hierarchal position imparted to Randomized Controlled Trials (RCTs) for new drug discovery and practice of evidence-based medicine. There is a need to reflect on the reason for many new drugs being withdrawn during post marketing surveillance. There are several examples in literature where drug-discovery has originated initially from keen clinical and / or laboratory observations. The roots of these discoveries have often been from observations made by practitioners of traditional medicine including Ayurveda. The present article draws attention to the scope and challenges for observational therapeutics. There is an urgent need for the meticulous planning for a systematic organization of developing observational therapeutics, with a full understanding of its strengths and limitations.

Observational therapeutics: Scope, challenges, and organization

Directory of Open Access Journals (Sweden)

Rama Vaidya

2011-01-01

Full Text Available The importance of Observational Therapeutics in the progress of medicine has been neglected in the current era of the hierarchal position imparted to Randomized Controlled Trials (RCTs for new drug discovery and practice of evidence-based medicine. There is a need to reflect on the reason for many new drugs being withdrawn during post marketing surveillance. There are several examples in literature where drug-discovery has originated initially from keen clinical and / or laboratory observations. The roots of these discoveries have often been from observations made by practitioners of traditional medicine including Ayurveda. The present article draws attention to the scope and challenges for observational therapeutics. There is an urgent need for the meticulous planning for a systematic organization of developing observational therapeutics, with a full understanding of its strengths and limitations.

Food marketing to children in Canada: a settings-based scoping review on exposure, power and impact

OpenAIRE

Rachel, Prowse

2017-01-01

Introduction: Food marketing impacts children’s food knowledge, behaviours and health. Current regulations in Canada focus on restricting promotional aspects of food marketing with little-to-no consideration of the places where children experience food. Understanding food marketing in children’s everyday settings is necessary to protect children. This scoping review describes the current literature on food marketing to children in Canada by setting. Methods: The author searched databases for ...

Liquid abrasive grit blasting literature search and decontamination scoping tests report

International Nuclear Information System (INIS)

Ferguson, R.L.

1993-10-01

Past decontamination and solvent recovery activities at the Idaho Chemical Processing Plant (ICPP) have resulted in the accumulation of 1.5 million gallons of radioactively contaminated sodium-bearing liquid waste. Future decontamination activities at the ICPP could result in the production of 5 million gallons or more of sodium-bearing waste using the current decontamination techniques of chemical/water flushes and steam jet cleaning. With the curtailment of reprocessing at the ICPP, the focus of decontamination is shifting from maintenance for continued operation of the facilities to decommissioning. As decommissioning plans are developed, new decontamination methods must be used which result in higher decontamination factors and generate lower amounts of sodium-bearing secondary waste. The primary initiative of the WINCO Decontamination Development Program is the development of methods to eliminate/minimize the use of sodium-bearing decontamination chemicals. One method that was chosen for cold scoping studies during FY-93 was abrasive grit blasting. Abrasive grit blasting has been used in many industries and a vast amount of research and development has already been conducted. However, new grits, process improvements and ICPP applicability was investigated. This evaluation report is a summary of the research efforts and scoping tests using the liquid abrasive grit blasting decontamination technique. The purpose of these scoping tests was to determine the effectiveness of three different abrasive grits: plastic beads, glass beads and alumina oxide

16 CFR 314.1 - Purpose and scope.

Science.gov (United States)

2010-01-01

... relationship, or pertains to the customers of other financial institutions that have provided such information... SAFEGUARDING CUSTOMER INFORMATION § 314.1 Purpose and scope. (a) Purpose. This part, which implements sections..., confidentiality, and integrity of customer information. (b) Scope. This part applies to the handling of customer...

29 CFR 4010.1 - Purpose and scope.

Science.gov (United States)

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Purpose and scope. 4010.1 Section 4010.1 Labor Regulations Relating to Labor (Continued) PENSION BENEFIT GUARANTY CORPORATION CERTAIN REPORTING AND DISCLOSURE REQUIREMENTS ANNUAL FINANCIAL AND ACTUARIAL INFORMATION REPORTING § 4010.1 Purpose and scope. This part...

28 CFR 32.31 - Scope of subpart.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Scope of subpart. 32.31 Section 32.31 Judicial Administration DEPARTMENT OF JUSTICE PUBLIC SAFETY OFFICERS' DEATH, DISABILITY, AND EDUCATIONAL ASSISTANCE BENEFIT CLAIMS Educational Assistance Benefit Claims § 32.31 Scope of subpart. Consistent with...

Scoping of flood hazard mapping needs for Cumberland County, Maine

Science.gov (United States)

Dudley, Robert W.; Schalk, Charles W.

2006-01-01

watersheds, and the characteristics of the watersheds have changed with time. Therefore, many of the older studies may not depict current conditions nor accurately estimate risk in terms of flood heights. The following is the scope of work as defined in the FEMA/USGS Statement of Work: Task 1: Collect data from a variety of sources including community surveys, other Federal and State Agencies, National Flood Insurance Program (NFIP) State Coordinators, Community Assistance Visits (CAVs) and FEMA archives. Lists of mapping needs will be obtained from the MNUSS database, community surveys, and CAVs, if available. FEMA archives will be inventoried for effective FIRM panels, FIS reports, and other flood-hazard data or existing study data. Best available base map information, topographic data, flood-hazard data, and hydrologic and hydraulic data will be identified. Data from the Maine Floodplain Management Program database also will be utilized. Task 2: Contact communities in Cumberland County to notify them that FEMA and the State have selected them for a map update, and that a project scope will be developed with their input. Topics to be reviewed with the communities include (1) Purpose of the Flood Map Project (for example, the update needs that have prompted the map update); (2) The community's mapping needs; (3) The community's available mapping, hydrologic, hydraulic, and flooding information; (4) target schedule for completing the project; and (5) The community's engineering, planning, and geographic information system (GIS) capabilities. On the basis of the collected information from Task 1 and community contacts/meetings in Task 2, the USGS will develop a Draft Project Scope for the identified mapping needs of the communities in Cumberland County. The following items will be addressed in the Draft Project Scope: review of available information, determine if and how effective FIS data can be used in new project, and identify other data needed to

Amniotic membrane seeded with mesenchymal adipose-derived stem cell for coverage of wound in third degree burn: An experimental study

Directory of Open Access Journals (Sweden)

Mohammad Javad Fatemi

2014-09-01

Conclusion: Acellular amnion seeded with adipose-derived stem cell can result in faster wound healing and better histopathology characteristic. The amnion as a scaffold and the fat derived stem cells as healing accelerator are recommended for coverage of the 3rd degree burn wounds after excision and it may reduce the need for skin graft.

28 CFR 541.40 - Purpose and scope.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Purpose and scope. 541.40 Section 541.40 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT INMATE DISCIPLINE AND SPECIAL HOUSING UNITS Control Unit Programs § 541.40 Purpose and scope. (a) In an effort to...

42 CFR 403.200 - Basis and scope.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Basis and scope. 403.200 Section 403.200 Public... PROVISIONS SPECIAL PROGRAMS AND PROJECTS Medicare Supplemental Policies § 403.200 Basis and scope. (a... intent of that section is to enable Medicare beneficiaries to identify Medicare supplemental policies...

10 CFR 60.1 - Purpose and scope.

Science.gov (United States)

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Purpose and scope. 60.1 Section 60.1 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.1 Purpose and scope. This part prescribes rules governing the licensing (including issuance...

22 CFR 171.40 - Purpose and scope.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Purpose and scope. 171.40 Section 171.40... PUBLIC Ethics in Government Act Provisions § 171.40 Purpose and scope. This subpart sets forth the... 2634, require that high-level Federal officials disclose publicly their personal financial interests. ...

28 CFR 16.21 - Purpose and scope.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Purpose and scope. 16.21 Section 16.21 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Production or Disclosure in Federal and State Proceedings § 16.21 Purpose and scope. (a) This subpart sets...

28 CFR 513.10 - Purpose and scope.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Purpose and scope. 513.10 Section 513.10 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE GENERAL MANAGEMENT AND ADMINISTRATION ACCESS TO RECORDS Production or Disclosure of FBI/NCIC Information § 513.10 Purpose and scope. This...

12 CFR 41.20 - Scope and definitions.

Science.gov (United States)

2010-01-01

... Affiliate Marketing § 41.20 Scope and definitions. (a) Scope. This subpart applies to national banks...-existing business relationship. (i) In general. The term “pre-existing business relationship” means a relationship between a person, or a person's licensed agent, and a consumer based on— (A) A financial contract...

40 CFR 57.801 - Purpose and scope.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Purpose and scope. 57.801 Section 57.801 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED... Technology § 57.801 Purpose and scope. (a) This subpart shall govern all proceedings for the waiver of the...

29 CFR 4245.1 - Purpose and scope.

Science.gov (United States)

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Purpose and scope. 4245.1 Section 4245.1 Labor Regulations Relating to Labor (Continued) PENSION BENEFIT GUARANTY CORPORATION INSOLVENCY, REORGANIZATION, TERMINATION, AND OTHER RULES APPLICABLE TO MULTIEMPLOYER PLANS NOTICE OF INSOLVENCY § 4245.1 Purpose and scope. (a...

5 CFR 1215.1 - Purpose and scope.

Science.gov (United States)

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Purpose and scope. 1215.1 Section 1215.1 Administrative Personnel MERIT SYSTEMS PROTECTION BOARD ORGANIZATION AND PROCEDURES DEBT MANAGEMENT Salary Offset § 1215.1 Purpose and scope. (a) This regulation provides procedures for the collection by administrative...

37 CFR 204.1 - Purposes and scope.

Science.gov (United States)

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Purposes and scope. 204.1 Section 204.1 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES PRIVACY ACT: POLICIES AND PROCEDURES § 204.1 Purposes and scope. The purposes of these...

Concrete decontamination scoping tests

International Nuclear Information System (INIS)

Archibald, K.E.

1995-01-01

This report details the research efforts and scoping tests performed at the Idaho Chemical Process Plant using scabbling, chemical, and electro-osmotic decontamination techniques on radiologically contaminated concrete

Monaco - IAEA [Marine Radioecology. Current Research and Future Scope

International Nuclear Information System (INIS)

Joseph, J.; Chipman, W.A.; Fukai, R.; Duursma, E.K.

1967-01-01

Present and future research: Transport of radionuclides by turbulent diffusion processes. The radionuclides which are introduced into the sea will be dispersed by turbulent processes caused by currents, tides, waves and so forth. One of the most urgent needs for estimation of radionuclide behaviour in the sea is to study such diffusion processes and to interpret and describe the results so that they can be used for prediction of similar processes affecting the dispersion of radioactive materials in marine environments

Negative affect varying in motivational intensity influences scope of memory.

Science.gov (United States)

Threadgill, A Hunter; Gable, Philip A

2018-04-06

Emotions influence cognitive processes involved in memory. While some research has suggested that cognitive scope is determined by affective valence, recent models of emotion-cognition interactions suggest that motivational intensity, rather than valence, influences these processes. The present research was designed to clarify how negative affects differing in motivational intensity impact memory for centrally or peripherally presented information. Experiments 1 & 2 found that, relative to a neutral condition, high intensity negative affect (anger) enhances memory for centrally presented information. Experiment 3 replicated this effect using another high intensity negative affect (threat). Experiment 4 extended this by finding that, relative to a neutral condition, low intensity negative affect (sadness) enhanced memory for peripherally presented information. Finally, in Experiment 5, the effects of sadness and threat on scope of memory were directly compared, finding that threat narrowed scope of memory, while sadness broadened scope of memory. Together, these results provide additional support for the motivational dimensional model of cognitive scope, in that high intensity emotions narrow cognitive scope, while low intensity emotions broaden cognitive scope.

Scoping in environmental impact assessment: Balancing precaution and efficiency?

International Nuclear Information System (INIS)

Snell, Tim; Cowell, Richard

2006-01-01

Scoping is a crucial yet under-researched stage of environmental impact assessment, in which practice falls well behind conceptual ideals. We argue that such 'implementation deficits' reflect dilemmas between two key rationales for scoping - environmental precaution and decision-making efficiency - and between technical and participatory conceptions of the decision-making process. We use qualitative research to understand how scoping practice in the UK reconciles these competing imperatives. Our findings suggest that practitioners mainly rationalise their approach in terms of decision-making efficiency, while justifying excluding the public from scoping on grounds of prematurity, delay and risks of causing confusion. The tendency to scope issues in rather than exclude them reflects a pervasive concern for legal challenge, rather than environmental precaution, but this reinforces standard lists of environmental considerations rather than the investigation of novel, cumulative or indirect risks

77 FR 9893 - Notice of Scope Rulings

Science.gov (United States)

2012-02-21

... feedstock exported from the PRC to Mexico and then processed into granular magnesium before exportation to... exported from Japan is within the scope of the antidumping duty and countervailing duty orders; requested... electric blanket is not within the scope of the antidumping duty order; April 14, 2011. Japan A-588-804...

32 CFR 99.1 - Scope and purpose.

Science.gov (United States)

2010-07-01

... 32 National Defense 1 2010-07-01 2010-07-01 false Scope and purpose. 99.1 Section 99.1 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN PROCEDURES FOR STATES AND LOCALITIES TO REQUEST INDEMNIFICATION § 99.1 Scope and purpose. (a) The Department...

48 CFR 504.500 - Scope of subpart.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Scope of subpart. 504.500 Section 504.500 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION GENERAL ADMINISTRATIVE MATTERS Electronic Commerce in Contracting 504.500 Scope of subpart. This subpart provides policy and procedure for use of GSA's Electronic...

30 CFR 259.001 - Purpose and scope.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Purpose and scope. 259.001 Section 259.001 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE MINERAL LEASING: DEFINITIONS § 259.001 Purpose and scope. The purpose of this part 259 is to define various terms appearing in...

10 CFR 440.1 - Purpose and scope.

Science.gov (United States)

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Purpose and scope. 440.1 Section 440.1 Energy DEPARTMENT... scope. This part implements a weatherization assistance program to increase the energy efficiency of... with children, high residential energy users, and households with high energy burden. [65 FR 77217, Dec...

50 CFR 19.2 - Scope of regulations.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Scope of regulations. 19.2 Section 19.2... PLANTS (CONTINUED) AIRBORNE HUNTING Introduction § 19.2 Scope of regulations. The regulations contained... United States citizens whether within the territorial jurisdiction of the United States or on the high...

10 CFR 63.1 - Purpose and scope.

Science.gov (United States)

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Purpose and scope. 63.1 Section 63.1 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA General Provisions § 63.1 Purpose and scope. This part prescribes rules governing the...

Fuzzy decision analysis for project scope change management

OpenAIRE

Farshad Shirazi; Hamed Kazemipoor; Reza Tavakkoli-Moghaddam

2017-01-01

It is very important to manage and control projects with the consideration of the triple constraints; namely time, cost and scope. It is also extremely important to manage the scope and all the procurements needed to complete any project. During the project’s lifecycle many changes take place, either positively or negatively, which should be controlled. If the changes are not controlled we may have scope creep that has negative effect on the project. It is commonly considered a negative incid...

Wound, Ostomy, and Continence Nursing: Scope and Standards of Practice, 2nd Edition: An Executive Summary.

Science.gov (United States)

2018-04-25

Wound, ostomy, and continence (WOC) nursing was recognized as a nursing specialty by the American Nurses Association in February 2010, and the Society published the original scope and standards of WOC nursing practice in May 2010. The Wound, Ostomy, and Continence Nursing: Scope and Standards of Practice, 2nd Edition is the definitive resource promoting excellence in professional practice, quality care, and improved patient outcomes in WOC specialty practice. It can be used to articulate the value of WOC nurses to administrators, legislators, payers, patients, and others. The second edition also provides an overview of the scope of WOC nursing practice including a description of the specialty, the history and evolution of WOC nursing, characteristics of WOC nursing practice, and description of the trispecialty. The document describes various WOC nurse roles, populations served, practice settings, care coordination, and collaboration. Educational preparation, levels of practice within WOC specialty nursing, certification, mandate for continuous professional development, ethics, current trends, future considerations and challenges, and standards of WOC nursing practice and professional performance with competencies for each standard are provided. The purpose of this Executive Summary is to describe the process for developing the scope and standards document, provide an overview of the scope of WOC nursing practice, and list the standards of practice and professional performance along with the competencies for each level of WOC nurse provider. The original document is available from the WOCN Society's online book store (www.wocn.org).

A novel three-dimensional and high-definition flexible scope.

Science.gov (United States)

Nishiyama, Kenichi; Natori, Yoshihiro; Oka, Kazunari

2014-06-01

Recent high-tech innovations in digital surgical technology have led to advances in three-dimensional (3D) and high-definition (HD) operating scopes. We introduce a novel 3D-HD flexible surgical scope called "3D-Eye-Flex" and evaluate its utility as an alternative to the operating microscope. The 3D-Eye-Flex has a 15 mm long 3D-HD scope-head with a 15 mm outer diameter, a focus distance of 18-100 mm and 80° angle of view. Attached to a 615-mm-long flexible bellows, 3D-Eye-Flex can be easily fixed to the operating table. Microsurgical dissection of wet brain tissue and drilling a skull base model were performed under the scope while using the 3D-HD video monitor. This scope system provided excellent illumination and image quality during the procedures. A large depth of field with stereoscopic vision had a greater advantage over using an operating microscope. 3D-Eye-Flex was easy to manipulate and provided an abundance of space above the operative field. Surgeons felt comfortable while working and could easily shift the position of the scope. This novel 3D-HD flexible scope is an effective alternative to the operating microscope as a new surgeon's eye and will be suitable for digital image-based surgery with further refinement.

The Role of Progesterone and a Novel Progesterone Receptor, Progesterone Receptor Membrane Component 1, in the Inflammatory Response of Fetal Membranes to Ureaplasma parvum Infection.

Directory of Open Access Journals (Sweden)

Liping Feng

Full Text Available Ureaplasma parvum (U. parvum is gaining recognition as an important pathogen for chorioamnionitis and preterm premature rupture of membranes. We aimed to investigate the roles of progesterone (P4 and a novel progesterone receptor, progesterone receptor membrane component 1 (PGRMC1, in the response of fetal membranes to U. parvum. Fetal membrane cells (amnion, chorion and decidua were isolated and confirmed to be free of Mycoplasmataceae. Cells were treated with U. parvum (5x106 CFU, and adherence was quantified by qPCR. Amnion and chorion cells were transfected with scrambled siRNA or validated PGRMC1 siRNA for 72h. Cells were then treated with U. parvum for 4h with or without pretreatment with P4 (10-7 M or ethanol for 1h. Interleukin-8 (IL-8, matrix metalloproteinase 9 (MMP9 and cyclooxygenase (COX-2 mRNA expression were quantified by qRT-PCR. Culture medium was harvested and analyzed for IL-8 and prostaglandin (PGE2 secretion by ELISA and MMP9 activity by zymography. U. parvum had a mean adherence of 15.0±0.6%, 16.9± 3.7% and 4.7±0.3% in cultured amnion, chorion and decidua cells, respectively. Exposure to U. parvum elicited significant inflammatory responses including induction of IL-8, COX-2, PGE2 and MMP9. A possible role of PGRMC1 was identified in the inhibition of U. parvum-stimulated COX-2 and MMP9 mRNA expression in chorion cells and MMP9 activity in amnion cells. On the other hand, it might enhance the U. parvum-stimulated IL-8 protein secretion in amnion cells. P4, mediated through PGRMC1, significantly inhibited U. Parvum-induced MMP9 mRNA and COX-2 mRNA expression in chorion cells. P4 appeared to attenuate U. parvum induced IL-8 mRNA expression in chorion cells, but this P4 effect might not mediated through PGRMC1. In summary, U. parvum preferentially adheres to and induces inflammatory responses in chorion and amnion cells. P4 and PGRMC1 appear to differentially modulate the inflammatory responses induced by U. parvum among

10 CFR 1009.1 - Purpose and scope.

Science.gov (United States)

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Purpose and scope. 1009.1 Section 1009.1 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) GENERAL POLICY FOR PRICING AND CHARGING FOR MATERIALS AND SERVICES SOLD BY DOE § 1009.1 Purpose and scope. (a) This part establishes Department of Energy policy for...

25 CFR 39.1000 - Purpose and scope.

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Purpose and scope. 39.1000 Section 39.1000 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION THE INDIAN SCHOOL EQUALIZATION PROGRAM Administrative Cost Formula § 39.1000 Purpose and scope. The purpose of this subpart is to provide funds at the...

40 CFR 82.150 - Purpose and scope.

Science.gov (United States)

2010-07-01

...) PROTECTION OF STRATOSPHERIC OZONE Recycling and Emissions Reduction § 82.150 Purpose and scope. (a) The purpose of this subpart is to reduce emissions of class I and class II refrigerants and their substitutes... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Purpose and scope. 82.150 Section 82...

7 CFR 634.1 - Purpose and scope.

Science.gov (United States)

2010-01-01

... 7 Agriculture 6 2010-01-01 2010-01-01 false Purpose and scope. 634.1 Section 634.1 Agriculture... AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM General § 634.1 Purpose and scope. (a) The purpose... from agricultural activities. The proposed project area must be within a high priority area in an...

45 CFR 63.1 - Purpose and scope.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Purpose and scope. 63.1 Section 63.1 Public... OFFICE OF THE ASSISTANT SECRETARY FOR PLANNING AND EVALUATION General § 63.1 Purpose and scope. (a... analyses, and demonstrations and evaluations which have demonstrated a high probability of impacting on the...

28 CFR 550.10 - Purpose and scope.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Purpose and scope. 550.10 Section 550.10... Alcohol Testing § 550.10 Purpose and scope. The Bureau of Prisons maintains a surveillance program in..., or who are considered high risks based on behavior observed or on information received by staff. (a...

50 CFR 85.10 - Purpose and scope.

Science.gov (United States)

2010-10-01

...) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM CLEAN VESSEL ACT GRANT PROGRAM General § 85.10 Purpose and scope. The purpose of this part is to establish requirements for state participation in the... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Purpose and scope. 85.10 Section 85.10...

10 CFR 420.1 - Purpose and scope.

Science.gov (United States)

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Purpose and scope. 420.1 Section 420.1 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION STATE ENERGY PROGRAM General Provisions for State Energy Program Financial Assistance § 420.1 Purpose and scope. It is the purpose of this part to promote the conservation...

28 CFR 549.60 - Purpose and scope.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Purpose and scope. 549.60 Section 549.60 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT MEDICAL SERVICES Hunger Strikes, Inmate § 549.60 Purpose and scope. The Bureau of Prisons provides guidelines for the medical and administrative management of...

Scope of algae as third generation biofuels

Directory of Open Access Journals (Sweden)

Shuvashish eBehera

2015-02-01

Full Text Available An initiative has been taken to develop different solid, liquid and gaseous biofuels as the alternative energy resources. The current research and technology based on the third generation biofuels derived from algal biomass have been considered as the best alternative bioresource that avoids the disadvantages of first and second generation biofuels. Algal biomass have been investigated for the implementation of economic conversion processes producing different biofuels such as biodiesel, bioethanol, biogas, biohydrogen and other valuable co-products. In the present review, the recent findings and advance developments in algal biomass for improved biofuel production. This review discusses about the importance of the algal cell contents, various strategies for product formation through various conversion technologies, and its future scope as an energy security.

17 CFR 248.101 - Purpose and scope.

Science.gov (United States)

2010-04-01

...) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.101 Purpose and scope. (a...”), regulates the use of consumer information received from an affiliate to make marketing solicitations. (b) Scope. This subpart applies to any broker or dealer other than a notice-registered broker or dealer, to...

12 CFR 503.1 - Scope and procedures.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Scope and procedures. 503.1 Section 503.1 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY PRIVACY ACT § 503.1 Scope and... & Services Division, Office of Thrift Supervision, 1700 G Street, NW., Washington, DC 20552. (c) Requests for...

45 CFR 148.306 - Basis and scope.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Basis and scope. 148.306 Section 148.306 Public... FOR THE INDIVIDUAL HEALTH INSURANCE MARKET Grants to States for Operation of Qualified High Risk Pools § 148.306 Basis and scope. This subpart implements section 2745 of the Public Health Service Act (PHS...

50 CFR 660.701 - Purpose and scope.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Purpose and scope. 660.701 Section 660.701... Purpose and scope. This subpart implements the Fishery Management Plan for U.S. West Coast Fisheries for... the U.S. EEZ off the coasts of Washington, Oregon, and California and in adjacent high seas waters. ...

28 CFR 544.70 - Purpose and scope.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Purpose and scope. 544.70 Section 544.70... Literacy Program § 544.70 Purpose and scope. Except as provided for in § 544.71, an inmate confined in a federal institution who does not have a verified General Educational Development (GED) credential or high...

28 CFR 550.30 - Purpose and scope.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Purpose and scope. 550.30 Section 550.30... Urine Surveillance § 550.30 Purpose and scope. The Warden shall establish programs of urine testing for drug use, to monitor specific groups or individual inmates who are considered as high risk for drug use...

10 CFR 4.301 - Purpose and scope.

Science.gov (United States)

2010-01-01

... FINANCIAL ASSISTANCE FROM THE COMMISSION Regulations Implementing the Age Discrimination Act of 1975, as Amended General § 4.301 Purpose and scope. The purpose of this subpart is to set forth NRC policies and... 10 Energy 1 2010-01-01 2010-01-01 false Purpose and scope. 4.301 Section 4.301 Energy NUCLEAR...

29 CFR 18.1 - Scope of rules.

Science.gov (United States)

2010-07-01

... 29 Labor 1 2010-07-01 2010-07-01 true Scope of rules. 18.1 Section 18.1 Labor Office of the Secretary of Labor RULES OF PRACTICE AND PROCEDURE FOR ADMINISTRATIVE HEARINGS BEFORE THE OFFICE OF ADMINISTRATIVE LAW JUDGES General § 18.1 Scope of rules. (a) General application. These rules of practice are...

πScope: Python based scientific workbench with MDSplus data visualization tool

Energy Technology Data Exchange (ETDEWEB)

Shiraiwa, S., E-mail: shiraiwa@PSFC.MIT.EDU; Fredian, T.; Hillairet, J.; Stillerman, J.

2016-11-15

Highlights: • πScope provides great enhancement in MDSplus data visualization. • πScope provides a single platform for both data browsing and complicated analysis. • πScope is scriptable and easily expandable due to its object oriented. • πScope is written in python and available from (http://piscope.psfc.mit.edu/). - Abstract: A newly developed python based scientific data analysis and visualization tool, πScope ( (http://piscope.psfc.mit.edu)), is reported. The primary motivation is 1) to provide an updated tool to browse the MDSplus data beyond existing dwscope/jScope and 2) to realize a universal foundation to construct interface tools to perform computer modeling from experimental data. To visualize MDSplus data, πScope has many features including overplotting different signals and discharges, generating various plot types (line, contour, image, etc.), performing in-panel data analysis using python scripts, and producing publication quality graphics. The logic to generate multi-panel plots is designed to be backward compatible with dwscope, enabling smooth migration for users. πScope uses multi-threading in data loading, and is easy to modify and expand due to its object-oriented design. Furthermore, A user can access the data structure both from a GUI and a script, enabling relatively complex data analysis workflow built quickly on πScope.

πScope: Python based scientific workbench with MDSplus data visualization tool

International Nuclear Information System (INIS)

Shiraiwa, S.; Fredian, T.; Hillairet, J.; Stillerman, J.

2016-01-01

Highlights: • πScope provides great enhancement in MDSplus data visualization. • πScope provides a single platform for both data browsing and complicated analysis. • πScope is scriptable and easily expandable due to its object oriented. • πScope is written in python and available from (http://piscope.psfc.mit.edu/). - Abstract: A newly developed python based scientific data analysis and visualization tool, πScope ( (http://piscope.psfc.mit.edu)), is reported. The primary motivation is 1) to provide an updated tool to browse the MDSplus data beyond existing dwscope/jScope and 2) to realize a universal foundation to construct interface tools to perform computer modeling from experimental data. To visualize MDSplus data, πScope has many features including overplotting different signals and discharges, generating various plot types (line, contour, image, etc.), performing in-panel data analysis using python scripts, and producing publication quality graphics. The logic to generate multi-panel plots is designed to be backward compatible with dwscope, enabling smooth migration for users. πScope uses multi-threading in data loading, and is easy to modify and expand due to its object-oriented design. Furthermore, A user can access the data structure both from a GUI and a script, enabling relatively complex data analysis workflow built quickly on πScope.

Stem cell therapy to protect and repair the developing brain: a review of mechanisms of action of cord blood and amnion epithelial derived cells

Directory of Open Access Journals (Sweden)

Margie eCastillo-Melendez

2013-10-01

Full Text Available In the research, clinical and wider community there is great interest in the use of stem cells to reduce the progression, or indeed repair brain injury. Perinatal brain injury may result from acute or chronic insults sustained during fetal development, during the process of birth, or in the newborn period. The most readily identifiable outcome of perinatal brain injury is cerebral palsy, however this is just one consequence in a spectrum of mild to severe neurological deficits. As we review, there are now clinical trials taking place worldwide targeting cerebral palsy with stem cell therapies. It will likely be many years before strong evidence-based results emerge from these trials. With such trials underway, it is both appropriate and timely to address the physiological basis for the efficacy of stem-like cells in preventing damage to, or regenerating, the newborn brain. Appropriate experimental animal models are best placed to deliver this information. Cell availability, the potential for immunological rejection, ethical and logistical considerations, together with the propensity for native cells to form terratomas, make it unlikely that embryonic or fetal stem cells will be practical. Fortunately, these issues do not pertain to the use of human amnion epithelial cells (hAECs, or umbilical cord blood (UCB stem cells that are readily and economically obtained from the placenta and umbilical cord discarded at birth. These cells have the potential for transplantation to the newborn where brain injury is diagnosed or even suspected. We will explore the novel characteristics of hAECs and undifferentiated UCB cells, as well as UCB-derived endothelial progenitor cells and mesenchymal stem cells, and how immunomodulation and anti-inflammatory properties are principal mechanisms of action that are common to these cells, and which in turn may ameliorate the cerebral hypoxia and inflammation that are final pathways in the pathogenesis of perinatal brain

How Young Children Learn To Read in High/Scope Programs: A Series of Position Papers.

Science.gov (United States)

High/Scope Educational Research Foundation, Ypsilanti, MI.

Current debates regarding teaching children to read are centered around the most effective way to establish a foundation for literacy in the early years. This document is comprised of a set of three position papers on how the High/Scope Educational Research Foundation teaches young children to read in its infant-toddler, preschool, and early…

Scoping review protocol: education initiatives for medical psychiatry collaborative care.

Science.gov (United States)

Shen, Nelson; Sockalingam, Sanjeev; Abi Jaoude, Alexxa; Bailey, Sharon M; Bernier, Thérèse; Freeland, Alison; Hawa, Aceel; Hollenberg, Elisa; Woldemichael, Bethel; Wiljer, David

2017-09-03

The collaborative care model is an approach providing care to those with mental health and addictions disorders in the primary care setting. There is a robust evidence base demonstrating its clinical and cost-effectiveness in comparison with usual care; however, the transitioning to this new paradigm of care has been difficult. While there are efforts to train and prepare healthcare professionals, not much is known about the current state of collaborative care training programmes. The objective of this scoping review is to understand how widespread these collaborative care education initiatives are, how they are implemented and their impacts. The scoping review methodology uses the established review methodology by Arksey and O'Malley. The search strategy was developed by a medical librarian and will be applied in eight different databases spanning multiple disciplines. A two-stage screening process consisting of a title and abstract scan and a full-text review will be used to determine the eligibility of articles. To be included, articles must report on an existing collaborative care education initiative for healthcare providers. All articles will be independently assessed for eligibility by pairs of reviewers, and all eligible articles will be abstracted and charted in duplicate using a standardised form. The extracted data will undergo a 'narrative review' or a descriptive analysis of the contextual or process-oriented data and simple quantitative analysis using descriptive statistics. Research ethics approval is not required for this scoping review. The results of this scoping review will inform the development of a collaborative care training initiative emerging from the Medical Psychiatry Alliance, a four-institution philanthropic partnership in Ontario, Canada. The results will also be presented at relevant national and international conferences and published in a peer-reviewed journal. © Article author(s) (or their employer(s) unless otherwise stated in

The Advantages of High/Scope: Helping Children Lead Successful Lives.

Science.gov (United States)

Schweinhart, Lawrence J.; Weikart, David P.

1999-01-01

The High/Scope educational approach emphasizes child-initiated learning activities for preschool/elementary school children. A research study shows that compared to children receiving direct instruction, High/Scope kids later showed more prosocial and less antisocial behaviors. Another study showed that poor High/Scope students had better…

12 CFR 8.1 - Scope and application.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Scope and application. 8.1 Section 8.1 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY ASSESSMENT OF FEES § 8.1 Scope and application. The assessments contained in this part are made pursuant to the authority contained in 12 U.S.C...

45 CFR 99.1 - Scope of rules.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Scope of rules. 99.1 Section 99.1 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PROCEDURE FOR HEARINGS FOR THE CHILD CARE AND DEVELOPMENT FUND General § 99.1 Scope of rules. (a) The rules of procedure in this section govern the practice...

12 CFR 505.1 - Basis and scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Basis and scope. 505.1 Section 505.1 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY FREEDOM OF INFORMATION ACT § 505.1 Basis and scope. (a) This part is issued by the Office of Thrift Supervision (“OTS”) as a supplement to the...

12 CFR 513.1 - Scope of part.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Scope of part. 513.1 Section 513.1 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY PRACTICE BEFORE THE OFFICE § 513.1 Scope of part. This part prescribes rules with regard to general practice before the Office on one's own...

10 CFR 715.1 - Purpose and scope.

Science.gov (United States)

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Purpose and scope. 715.1 Section 715.1 Energy DEPARTMENT OF ENERGY DEFINITION OF NON-RECOURSE PROJECT-FINANCED § 715.1 Purpose and scope. This part sets forth the definition of “nonrecourse project-financed” as that term is used to define “new independent power...

27 CFR 479.81 - Scope of tax.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 3 2010-04-01 2010-04-01 false Scope of tax. 479.81... OTHER FIREARMS Transfer Tax § 479.81 Scope of tax. Except as otherwise provided in this part, each transfer of a firearm in the United States is subject to a tax to be represented by an adhesive stamp of...

FedScope Accessions Cubes

Data.gov (United States)

Office of Personnel Management — This raw data set provides the actual number of personnel actions ("Transfer-Ins" and "New Hires") that have taken place within a Fiscal Year. The scope of this raw...

Role of human amnion-derived mesenchymal stem cells in promoting osteogenic differentiation by influencing p38 MAPK signaling in lipopolysaccharide -induced human bone marrow mesenchymal stem cells

International Nuclear Information System (INIS)

Wang, Yuli; Wu, Hongxia; Shen, Ming; Ding, Siyang; Miao, Jing; Chen, Ning

2017-01-01

Periodontitis is a chronic inflammatory disease induced by bacterial pathogens, which not only affect connective tissue attachments but also cause alveolar bone loss. In this study, we investigated the anti-inflammatory effects of Human amnion-derived mesenchymal stem cells (HAMSCs) on human bone marrow mesenchymal stem cells (HBMSCs) under lipopolysaccharide (LPS)-induced inflammatory conditions. Proliferation levels were measured by flow cytometry and immunofluorescence staining of 5-ethynyl-2′-deoxyuridine (EdU). Osteoblastic differentiation and mineralization were investigated using chromogenic alkaline phosphatase activity (ALP) activity substrate assays, Alizarin red S staining, and RT-PCR analysis of HBMSCs osteogenic marker expression. Oxidative stress induced by LPS was investigated by assaying reactive oxygen species (ROS) level and superoxide dismutase (SOD) activity. Here, we demonstrated that HAMSCs increased the proliferation, osteoblastic differentiation, and SOD activity of LPS-induced HBMSCs, and down-regulated the ROS level. Moreover, our results suggested that the activation of p38 MAPK signal transduction pathway is essential for reversing the LPS-induced bone-destructive processes. SB203580, a selective inhibitor of p38 MAPK signaling, significantly suppressed the anti-inflammatory effects in HAMSCs. In conclusion, HAMSCs show a strong potential in treating inflammation-induced bone loss by influencing p38 MAPK signaling. - Highlights: • LPS inhibites osteogenic differentiation in HBMSCs via suppression of p38 MAPK signaling pathway. • HAMSCs promote LPS-induced HBMSCs osteogenic differentiation through p38 MAPK signaling pathway. • HAMSCs reverse LPS-induced oxidative stress in LPS-induced HBMSCs through p38 MAPK signaling pathway.

Studies of hemidesmosomes in human amnion: the use of a detergent extraction protocol for compositional and ultrastructural analysis and preparation of a hemidesmosome-enriched fraction from tissue.

Science.gov (United States)

Behzad, F; Jones, C J; Ball, S; Alvares, T; Aplin, J D

1995-01-01

A method is described for the sequential detergent and high ionic strength extraction of human amnion with the progressive enrichment of the intermediate filament (IF) cytoskeleton and its associated structures including hemidesmosomes (HD). TEM of the extracted epithelium in situ reveals IF bundles beneath the apical cell surface, around the nucleus and at the lateral edges of the cells where association with desmosomes occurs. IF bundles are also very prominent within basal cell processes where they loop through the cytoplasm adjacent to the HDs. A novel connecting filament network is observed running between the IFs and the hemidesmosomal dense plaque. The adjacent IF network contains both cytokeratin and vimentin, the latter revealed much more fully as a result of the extraction protocol. The hemidesmosomal plasma membrane contains integrin subunits alpha 6 and beta 4 and these are quantitatively retained as the basal cell surface during extraction, while nonjunctional plasma membrane is solubilised. Integrin beta 1 is found at the basolateral cell surface but, like actin, is extracted quantitatively and is not present in HDs. The extracted epithelial cells may be recovered by scraping and the IF network depolymerised to produce a particulate fraction containing short residual IFs, associated thin filaments and plaque material. This fraction contains immunoreactive cytokeratin and vimentin. Integrin alpha 6 beta 4 has been used as a biochemical criterion of the presence of HD material in the fraction. Both subunits are highly enriched. The fraction also contains the hemidesmosomal components HD1, BP230 and BP180. This method is likely to be useful in further characterisation of the HD.

RADAR PPI Scope Overlay

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — RADAR PPI Scope Overlays are used to position a RADAR image over a station at the correct resolution. The archive maintains several different RADAR resolution types,...

Building A Collaborative And Distributed E&O Program For EarthScope

Science.gov (United States)

Hall-Wallace, M. K.; Boyd, T.; Richard, G.; Ellins, K.; Meertens, C.; Semken, S.; Taber, J.; Benthien, M.; Wald, L.; Marvinney, R.

2003-12-01

EarthScope's education and outreach (E&O) mission is to ensure that the EarthScope experiment creates as its legacy a public more knowledgeable and understanding of the scientific and societal contributions made by the EarthScope experiment and Earth science. It will fulfill this commitment by developing and disseminating programs and products that utilize the data, models, technology and discoveries of EarthScope. The EarthScope Education and Outreach Network (EON), consisting of local EON alliances, the EarthScope facilities, partner organizations and a coordinating office, will facilitate this E&O mission. The local EON alliances, which will vary in size and purpose to respond quickly and to meet the specific needs in a region, will carry out the bulk of the effort. Thus, EarthScope EON can provide customized services that engage culturally, economically and geographically diverse audiences at the national and local scales. The EarthScope facilities and research community will provide access to data, models, and visualization tools for educational purposes. Partnerships with other national and local science education and outreach programs at colleges, universities, research facilities and professional societies within the EarthScope community as well as relevant programs at museums and parks, state geologic surveys and emergency management agencies, and K-12 schools are critical to EON's success. These partnerships will allow EON to use existing resources, networks and expertise to gear up quickly and efficiently. As EON develops, it will reciprocate by contributing new resources and expertise to the partnerships that help improve public understanding of Earth systems overall and promote effective application of EarthScope discoveries. In this presentation, we will outline major programs and products envisioned for EarthScope, plans for evaluating those programs locally and nationally, and mechanisms for collaborating with existing E&O programs.

Teleradiology - current status

International Nuclear Information System (INIS)

Baltadjiev, D.; Charakchiev

2000-01-01

Tele-radiology is a term becoming increasingly popular in the medical literature. Nevertheless, terminological definitions in this particular field are still rather vague. The scope of applications extend from simple image presenting via analogue telephone lines to transmission of 3-D medical images through a satellite. It is a matter of standards highly differing in terms of data transmission rates, safety, technical demands on the systems and the like. In this article new information technologies, technical aspects, as well as some major applications of tele-radiology are discussed. The current status of tele-medicine/tele-radiology in this country is likewise briefly outlined

Integrating EarthScope Research and Education on a National Scale

Science.gov (United States)

Hall-Wallace, M. K.; Boyd, T.; Richard, G.; Ellins, K.; Meertens, C.; Semken, S.; Taber, J.; Benthien, M.; Wald, L.; Marvinney, R.

2002-12-01

EarthScope's education and outreach mission is to ensure the EarthScope experiment creates as its legacy a public more knowledgeable and understanding of the scientific and societal contributions made by the EarthScope experiment and Earth science. It will fulfill this commitment by developing and disseminating products that utilize the data, models, technology and discoveries of EarthScope and that support existing education and outreach programs. EarthScope EON will carry out educational activities ranging from research experiences for students in grades K-16 to professional development for technical professionals and educators in both formal (e.g. K-20 classrooms) and informal (e.g. museums and parks) venues. It will also provide a wide range of outreach activities from organizing town halls or other local meetings in advance of an instrument deployment, to developing radio, print and video materials that inform the public about the EarthScope experiment and discoveries. The EarthScope Education and Outreach Network (EON) will be facilitated and coordinated through a national center; however, the bulk of the effort will be distributed among local EON alliances of various sizes designed to respond quickly and to meet the specific needs in a region. This allows EarthScope EON to provide customized services that engage culturally, economically and geographically diverse audiences at the national and local scales. The network will be built through national and local partnerships with existing science education and outreach programs at colleges, universities, research facilities and professional societies within the EarthScope community as well as relevant programs at museums and parks, state geologic surveys and emergency management agencies, and K-12 schools. These partnerships will allow EON to use existing resources, networks and expertise to gear up quickly and efficiently. As EON develops, it will reciprocate by contributing new resources and expertise to the

Mobile Health Initiatives in Vietnam: Scoping Study.

Science.gov (United States)

Lam, Jeffrey A; Dang, Linh Thuy; Phan, Ngoc Tran; Trinh, Hue Thi; Vu, Nguyen Cong; Nguyen, Cuong Kieu

2018-04-24

Mobile health (mHealth) offers a promising solution to the multitude of challenges the Vietnamese health system faces, but there is a scarcity of published information on mHealth in Vietnam. The objectives of this scoping study were (1) to summarize the extent, range, and nature of mHealth initiatives in Vietnam and (2) to examine the opportunities and threats of mHealth utilization in the Vietnamese context. This scoping study systematically identified and extracted relevant information from 20 past and current mHealth initiatives in Vietnam. The study includes multimodal information sources, including published literature, gray literature (ie, government reports and unpublished literature), conference presentations, Web-based documents, and key informant interviews. We extracted information from 27 records from the electronic search and conducted 14 key informant interviews, allowing us to identify 20 mHealth initiatives in Vietnam. Most of the initiatives were primarily funded by external donors (n=15), while other initiatives were government funded (n=1) or self-funded (n=4). A majority of the initiatives targeted vulnerable and hard-to-reach populations (n=11), aimed to prevent the occurrence of disease (n=12), and used text messaging (short message service, SMS) as part of their intervention (n=14). The study revealed that Vietnamese mHealth implementation has been challenged by factors including features unique to the Vietnamese language (n=4) and sociocultural factors (n=3). The largest threats to the popularity of mHealth initiatives are the absence of government policy, lack of government interest, heavy dependence on foreign funding, and lack of technological infrastructure. Finally, while current mHealth initiatives have already demonstrated promising opportunities for alternative models of funding, such as social entrepreneurship or private business models, sustainable mHealth initiatives outside of those funded by external donors have not yet been

Unhealthy smokers: scopes for prophylactic intervention and clinical treatment.

Science.gov (United States)

Prasad, Shikha; Kaisar, Mohammad Abul; Cucullo, Luca

2017-10-04

Globally, tobacco use causes approximately 6 million deaths per year, and predictions report that with current trends; more than 8 million deaths are expected annually by 2030. Cigarette smokings is currently accountable for more than 480,000 deaths each year in United States (US) and is the leading cause of preventable death in the US. On average, smokers die 10 years earlier than nonsmokers and if smoking continues at its current proportion among adolescents, one in every 13 Americans aged 17 years or younger is expected to die prematurely from a smoking-related illness. Even though there has been a marginal smoking decline of around 5% in recent years (2005 vs 2015), smokers still account for 15% of the US adult population. What is also concerning is that 41,000 out of 480,000 deaths results from secondhand smoke (SHS) exposure. Herein, we provide a detailed review of health complications and major pathological mechanisms including mutation, inflammation, oxidative stress, and hemodynamic and plasma protein changes associated with chronic smoking. Further, we discuss prophylactic interventions and associated benefits and provide a rationale for the scope of clinical treatment. Considering these premises, it is evident that much detailed translational and clinical studies are needed. Factors such as the length of smoking cessation for ex-smokers, the level of smoke exposure in case of SHS, pre-established health conditions, genetics (and epigenetics modification caused by chronic smoking) are few of the criteria that need to be evaluated to begin assessing the prophylactic and/or therapeutic impact of treatments aimed at chronic and former smokers (especially early stage ex-smokers) including those frequently subjected to second hand tobacco smoke exposure. Herein, we provide a detailed review of health complications and major pathological mechanisms including mutation, inflammation, oxidative stress, and hemodynamic and plasma protein changes associated with

12 CFR 348.1 - Authority, purpose, and scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Authority, purpose, and scope. 348.1 Section... POLICY MANAGEMENT OFFICIAL INTERLOCKS § 348.1 Authority, purpose, and scope. (a) Authority. This part is... foster competition by generally prohibiting a management official from serving two nonaffiliated...

12 CFR 212.1 - Authority, purpose, and scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Authority, purpose, and scope. 212.1 Section... MANAGEMENT OFFICIAL INTERLOCKS § 212.1 Authority, purpose, and scope. (a) Authority. This part is issued... competition by generally prohibiting a management official from serving two nonaffiliated depository...

Defining food literacy: A scoping review.

Science.gov (United States)

Truman, Emily; Lane, Daniel; Elliott, Charlene

2017-09-01

The term "food literacy" describes the idea of proficiency in food related skills and knowledge. This prevalent term is broadly applied, although its core elements vary from initiative to initiative. In light of its ubiquitous use-but varying definitions-this article establishes the scope of food literacy research by identifying all articles that define 'food literacy', analysing its key conceptualizations, and reporting outcomes/measures of this concept. A scoping review was conducted to identify all articles (academic and grey literature) using the term "food literacy". Databases included Medline, Pubmed, Embase, CAB Abstracts, CINAHL, Scopus, JSTOR, and Web of Science, and Google Scholar. Of 1049 abstracts, 67 studies were included. From these, data was extracted on country of origin, study type (methodological approach), primary target population, and the primary outcomes relating to food literacy. The majority of definitions of food literacy emphasize the acquisition of critical knowledge (information and understanding) (55%) over functional knowledge (skills, abilities and choices) (8%), although some incorporate both (37%). Thematic analysis of 38 novel definitions of food literacy reveals the prevalence of six themes: skills and behaviours, food/health choices, culture, knowledge, emotions, and food systems. Study outcomes largely focus on knowledge generating measures, with very few focusing on health related outcome measures. Current definitions of food literacy incorporate components of six key themes or domains and attributes of both critical and functional knowledge. Despite this broad definition of the term, most studies aiming to improve food literacy focus on knowledge related outcomes. Few articles address health outcomes, leaving an important gap (and opportunity) for future research in this field. Copyright © 2017 Elsevier Ltd. All rights reserved.

Plastic surgery in Nigeria-Scope and challenges

Directory of Open Access Journals (Sweden)

TOG Chukwuanukwu

2011-01-01

Full Text Available Background Plastic surgery as a major subspecialty of surgery has existed in Nigeria for several decades but the populace including medical practitioners are yet to fully appreciate its scope. This leads to very late presentation/referral of cases and management of cases that should have been referred by less qualified practitioners with attendant poor outcomes and complications. Most people still regard plastic surgery as being synonymous with cosmetic/aesthetic surgery but the scope goes far beyond this entity. It is therefore important that the public including medical practitioners who are the main sources of referral to the subspecialty are aware of the range of cases handled by plastic surgery units. The plastic surgeon in Nigeria is also faced with a lot of challenges ranging from the arduous task of one having to manage very many different and complicated cases to being very poorly equipped and appreciated. Objectives To educate the populace especially the medical practitioners on the scope of plastic surgery and the extent of development of the subspecialty in Nigeria and solicit for colleague′s cooperation in order to move plastic surgery forward. To also highlight the difficulties faced by the plastic surgeon in Nigeria and seeking help from appropriate quarters which will help to reduce unnecessary referrals abroad while improving the services rendered to patients locally. Conclusion Plastic surgery in Nigeria has developed significantly both in scope and manpower but it is still faced with a lot of challenges. Knowledge of its scope will help to reduce unnecessary referrals abroad while improving services/skill here in Nigeria.

The Moderating Influence of Broad-Scope Trust on Customer-Seller Relationships

DEFF Research Database (Denmark)

Hansen, Torben

2012-01-01

, respectively, this study investigates the moderating influence of BST on relationships between satisfaction, narrow-scope trust, and loyalty and also examines the direct influence of BST on these variables. The results indicate that whereas BST negatively moderates relationships between satisfaction and narrow......-scope trust and between narrow-scope trust and loyalty, BST positively moderates the relationship between satisfaction and loyalty. In addition, it is demonstrated that BST positively influences customer satisfaction and narrow-scope trust...

7 CFR 253.1 - General purpose and scope.

Science.gov (United States)

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false General purpose and scope. 253.1 Section 253.1... AGRICULTURE GENERAL REGULATIONS AND POLICIES-FOOD DISTRIBUTION ADMINISTRATION OF THE FOOD DISTRIBUTION PROGRAM FOR HOUSEHOLDS ON INDIAN RESERVATIONS § 253.1 General purpose and scope. This part describes the terms...

7 CFR 245.1 - General purpose and scope.

Science.gov (United States)

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false General purpose and scope. 245.1 Section 245.1 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF... SCHOOLS § 245.1 General purpose and scope. (a) This part established the responsibilities of State...

7 CFR 220.1 - General purpose and scope.

Science.gov (United States)

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false General purpose and scope. 220.1 Section 220.1 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SCHOOL BREAKFAST PROGRAM § 220.1 General purpose and scope. This part...

7 CFR 248.1 - General purpose and scope.

Science.gov (United States)

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false General purpose and scope. 248.1 Section 248.1... AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.1 General purpose and scope. This part announces regulations under which the Secretary of Agriculture shall carry...

7 CFR 251.1 - General purpose and scope.

Science.gov (United States)

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false General purpose and scope. 251.1 Section 251.1... AGRICULTURE GENERAL REGULATIONS AND POLICIES-FOOD DISTRIBUTION THE EMERGENCY FOOD ASSISTANCE PROGRAM § 251.1 General purpose and scope. This part announces the policies and prescribes the regulations necessary to...

7 CFR 235.1 - General purpose and scope.

Science.gov (United States)

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false General purpose and scope. 235.1 Section 235.1 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS STATE ADMINISTRATIVE EXPENSE FUNDS § 235.1 General purpose and scope...

41 CFR 115-1.100 - Scope of subpart.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Scope of subpart. 115-1.100 Section 115-1.100 Public Contracts and Property Management Federal Property Management Regulations System (Continued) ENVIRONMENTAL PROTECTION AGENCY 1-INTRODUCTION 1.1-Regulation System § 115-1.100 Scope...

30 CFR 75.813 - High-voltage longwalls; scope.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false High-voltage longwalls; scope. 75.813 Section... AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Underground High-Voltage Distribution High-Voltage Longwalls § 75.813 High-voltage longwalls; scope. Sections 75.814 through 75.822 of this...

Energy Data Base: subject categories and scope

International Nuclear Information System (INIS)

Bost, D.E.

1985-03-01

The subject scope of the Energy Data Base (EDB) encompasses all DOE-sponsored research. Broadly defined, EDB subject scope includes all technological aspects of energy production, conversion, and efficient utilization, and the economic, social, and political aspects as well. Scope notes are provided to define the extent of interest in certain subject areas, particularly areas of basic research. Cross references between categories are provided to aid both the categorization of information and its retrieval. Citations entered into DOE's computerized bibliographic information system are assigned six-digit subject category numbers to broadly group information for storage, retrieval, and manipulation. These numbers are used in the preparation of printed documents, such as bibliographies and abstract journals, to arrange the citations and to aid searching on the DOE/RECON on-line system

Potential antitumor therapeutic strategies of human amniotic membrane and amniotic fluid-derived stem cells.

Science.gov (United States)

Kang, N-H; Hwang, K-A; Kim, S U; Kim, Y-B; Hyun, S-H; Jeung, E-B; Choi, K-C

2012-08-01

As stem cells are capable of self-renewal and can generate differentiated progenies for organ development, they are considered as potential source for regenerative medicine and tissue replacement after injury or disease. Along with this capacity, stem cells have the therapeutic potential for treating human diseases including cancers. According to the origins, stem cells are broadly classified into two types: embryonic stem cells (ESCs) and adult stem cells. In terms of differentiation potential, ESCs are pluripotent and adult stem cells are multipotent. Amnion, which is a membranous sac that contains the fetus and amniotic fluid and functions in protecting the developing embryo during gestation, is another stem cell source. Amnion-derived stem cells are classified as human amniotic membrane-derived epithelial stem cells, human amniotic membrane-derived mesenchymal stem cells and human amniotic fluid-derived stem cells. They are in an intermediate stage between pluripotent ESCs and lineage-restricted adult stem cells, non-tumorigenic, and contribute to low immunogenicity and anti-inflammation. Furthermore, they are easily available and do not cause any controversial issues in their recovery and applications. Not only are amnion-derived stem cells applicable in regenerative medicine, they have anticancer capacity. In non-engineered stem cells transplantation strategies, amnion-derived stem cells effectively target the tumor and suppressed the tumor growth by expressing cytotoxic cytokines. Additionally, they also have a potential as novel delivery vehicles transferring therapeutic genes to the cancer formation sites in gene-directed enzyme/prodrug combination therapy. Owing to their own advantageous properties, amnion-derived stem cells are emerging as a new candidate in anticancer therapy.

Using EarthScope magnetotelluric data to improve the resilience of the US power grid: rapid predictions of geomagnetically induced currents

Science.gov (United States)

Schultz, A.; Bonner, L. R., IV

2016-12-01

Existing methods to predict Geomagnetically Induced Currents (GICs) in power grids, such as the North American Electric Reliability Corporation standard adopted by the power industry, require explicit knowledge of the electrical resistivity structure of the crust and mantle to solve for ground level electric fields along transmission lines. The current standard is to apply regional 1-D resistivity models to this problem, which facilitates rapid solution of the governing equations. The systematic mapping of continental resistivity structure from projects such as EarthScope reveals several orders of magnitude of lateral variations in resistivity on local, regional and continental scales, resulting in electric field intensifications relative to existing 1-D solutions that can impact GICs to first order. The computational burden on the ground resistivity/GIC problem of coupled 3-D solutions inhibits the prediction of GICs in a timeframe useful to protecting power grids. In this work we reduce the problem to applying a set of filters, recognizing that the magnetotelluric impedance tensors implicitly contain all known information about the resistivity structure beneath a given site, and thus provides the required relationship between electric and magnetic fields at each site. We project real-time magnetic field data from distant magnetic observatories through a robustly calculated multivariate transfer function to locations where magnetotelluric impedance tensors had previously been obtained. This provides a real-time prediction of the magnetic field at each of those points. We then project the predicted magnetic fields through the impedance tensors to obtain predictions of electric fields induced at ground level. Thus, electric field predictions can be generated in real-time for an entire array from real-time observatory data, then interpolated onto points representing a power transmission line contained within the array to produce a combined electric field prediction

40 CFR 710.4 - Scope of the inventory.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Scope of the inventory. 710.4 Section... ACT TSCA CHEMICAL INVENTORY REGULATIONS General Provisions § 710.4 Scope of the inventory. (a... is extracted from air by any means, will automatically be included in the inventory under the...

7 CFR 277.1 - General purpose and scope.

Science.gov (United States)

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false General purpose and scope. 277.1 Section 277.1 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF... AGENCIES § 277.1 General purpose and scope. (a) Purpose. This part establishes uniform requirements for the...

7 CFR 1485.10 - General purpose and scope.

Science.gov (United States)

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false General purpose and scope. 1485.10 Section 1485.10... FOREIGN MARKETS FOR AGRICULTURAL COMMODITIES Market Access Program § 1485.10 General purpose and scope. (a.../Market Access Program (EIP/MAP). It also establishes the general terms and conditions applicable to MAP...

7 CFR 281.1 - General purpose and scope.

Science.gov (United States)

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false General purpose and scope. 281.1 Section 281.1 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF... RESERVATIONS § 281.1 General purpose and scope. (a) These regulations govern the operation of the Food Stamp...

7 CFR 215.1 - General purpose and scope.

Science.gov (United States)

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false General purpose and scope. 215.1 Section 215.1... AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL MILK PROGRAM FOR CHILDREN § 215.1 General purpose and scope. This part announces the policies and prescribes the general regulations with respect to the Special Milk...

41 CFR 128-1.100 - Scope of subpart.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Scope of subpart. 128-1.100 Section 128-1.100 Public Contracts and Property Management Federal Property Management Regulations System (Continued) DEPARTMENT OF JUSTICE 1-INTRODUCTION 1.1-Regulation System § 128-1.100 Scope of...

12 CFR 208.30 - Authority, purpose, and scope.

Science.gov (United States)

2010-01-01

...). (b) Purpose and scope. This subpart C describes the requirements imposed upon member banks acting as... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Authority, purpose, and scope. 208.30 Section 208.30 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM...

41 CFR 101-39.4900 - Scope of subpart.

Science.gov (United States)

2010-07-01

...-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.49-Forms § 101-39.4900 Scope of subpart. This subpart provides the... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Scope of subpart. 101-39.4900 Section 101-39.4900 Public Contracts and Property Management Federal Property Management...

41 CFR 50-202.1 - Application and scope.

Science.gov (United States)

2010-07-01

... Contracts PUBLIC CONTRACTS, DEPARTMENT OF LABOR 202-MINIMUM WAGE DETERMINATIONS Application and Scope § 50-202.1 Application and scope. Not less than the minimum wages prescribed in this part shall be paid to... Walsh-Healey Public Contracts Act. The minimum wages prescribed in this part shall apply to all...

The music like scope of education. Education «through» the music and education «for» the music

Directory of Open Access Journals (Sweden)

José Manuel TOURIÑÁN LÓPEZ

2011-09-01

Full Text Available The aim of this article is the formation of criterion in favors of the music as scope of education. Inside the educational current system we can distinguish three areas of musical education: the musical professional training, the teacher training and general music education. It is important to maintain these distinctions for the development of the curriculum and for the identity of the competence of formation of teachers, student training and general education pupils. In order to build criteria, we will approach these questions in three paragraphs, the first one dedicated to the education «through» the music, where we develop the possibilities of music as general scope of education and as scope of general education. The following epigraph contemplates the education «for» the music, orientated to the professional and vocational development. And, finally, we come closer to music teacher training for the different educational levels.

42 CFR 456.150 - Scope.

Science.gov (United States)

2010-10-01

... ASSISTANCE PROGRAMS UTILIZATION CONTROL Utilization Control: Mental Hospitals § 456.150 Scope. This subpart prescribes requirements for control of utilization of inpatient services in mental hospitals, including...

12 CFR 568.1 - Authority, purpose, and scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Authority, purpose, and scope. 568.1 Section 568.1 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SECURITY PROCEDURES § 568.1 Authority, purpose, and scope. (a) This part is issued by the Office of Thrift Supervision (OTS...

7 CFR 225.1 - General purpose and scope.

Science.gov (United States)

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false General purpose and scope. 225.1 Section 225.1... AGRICULTURE CHILD NUTRITION PROGRAMS SUMMER FOOD SERVICE PROGRAM General § 225.1 General purpose and scope... primary purpose of the Program is to provide food service to children from needy areas during periods when...

7 CFR 285.1 - General purpose and scope.

Science.gov (United States)

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false General purpose and scope. 285.1 Section 285.1... COMMONWEALTH OF PUERTO RICO § 285.1 General purpose and scope. This part describes the general terms and... government of the Commonwealth of Puerto Rico for the purpose of designing and conducting a nutrition...

12 CFR 747.24 - Scope of document discovery.

Science.gov (United States)

2010-01-01

... act of Congress, or the principles of common law provide. (d) Time limits. All discovery, including... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Scope of document discovery. 747.24 Section 747... of Practice and Procedure § 747.24 Scope of document discovery. (a) Limits on discovery. (1) Subject...

10 CFR 2.1200 - Scope of subpart L.

Science.gov (United States)

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Scope of subpart L. 2.1200 Section 2.1200 Energy NUCLEAR... Hearing Procedures for NRC Adjudications § 2.1200 Scope of subpart L. The provisions of this subpart... and request the application of Subpart L procedures, and proceedings for the direct or indirect...

A scoping review of crisis teams managing dementia in older people

Directory of Open Access Journals (Sweden)

Streater A

2017-10-01

Full Text Available Amy Streater,1,2 Donna Maria Coleston-Shields,2 Jennifer Yates,2 Miriam Stanyon,2 Martin Orrell2 1Research and Development, North East London NHS Foundation Trust, Ilford, 2Institute of Mental Health, University of Nottingham, Nottingham, UK Background: Research on crisis teams for older adults with dementia is limited. This scoping review aimed to 1 conduct a systematic literature review reporting on the effectiveness of crisis interventions for older people with dementia and 2 conduct a scoping survey with dementia crisis teams mapping services across England to understand operational procedures and identify what is currently occurring in practice.Methods: For the systematic literature review, included studies were graded using the Critical Appraisal Skills Programme checklist. For the scoping survey, Trusts across England were contacted and relevant services were identified that work with people with dementia experiencing a mental health crisis.Results: The systematic literature review demonstrated limited evidence in support of crisis teams reducing the rate of hospital admissions, and despite the increase in number of studies, methodological limitations remain. For the scoping review, only half (51.8% of the teams had a care pathway to manage crises and the primary need for referral was behavioral or psychological factors.Conclusion: Evidence in the literature for the effectiveness of crisis teams for older adults with dementia remains limited. Being mainly cohort designs can make it difficult to evaluate the effectiveness of the intervention. In practice, it appears that the pathway for care managing crisis for people with dementia varies widely across services in England. There was a wide range of names given to the provision of teams managing crisis for people with dementia, which may reflect the differences in the setup and procedures of the service. To provide evidence on crisis intervention teams, a comprehensive protocol is required

Gaming, simulations and society research scope and perspective

CERN Document Server

Shiratori, R; Kato, F

2014-01-01

This book presents a current research scope and perspective of Simulation and Gaming.Theoretical problems of Simulation and Gaming will be examined with a view to improving the social sciences through the introduction of the techniques and concepts of Simulation and Gaming.The fields of economics, political science, psychology and business management can all be radically improved by introducing such techniques of Simulation and Gaming as the Agent-Based Modelling.Other important topics are the analysis of philosophical foundations in Simulation and Gaming as an academic discipline.The ever growing and massive popularity of PC and arcade games cannot be ignored.Their potential as agents of education and their essentially violent nature raise many ethical and moral problems that need to be addressed.

The current international financial crisis: how much is new?

OpenAIRE

Steven B. Kamin

1999-01-01

The paper surveys a broad array of data to compare the scope and impact of three emerging-market financial crises: the debt crisis of the 1980s, the Mexican financial crisis of 1994-95, and the current international financial crisis. While certain conventional views regarding the three episodes are supported by the data examined in this paper, we find that in several respects, the current crisis is more similar to prior emerging-market crisis episodes than is commonly believed.

Scope Complexity Options Risks Excursions (SCORE) Factor Mathematical Description.

Energy Technology Data Exchange (ETDEWEB)

Gearhart, Jared Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Samberson, Jonell Nicole [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Shettigar, Subhasini [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jungels, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Welch, Kimberly M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Dean A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2017-03-01

The purpose of the Scope, Complexity, Options, Risks, Excursions (SCORE) model is to estimate the relative complexity of design variants of future warhead options, resulting in scores. SCORE factors extend this capability by providing estimates of complexity relative to a base system (i.e., all design options are normalized to one weapon system). First, a clearly defined set of scope elements for a warhead option is established. The complexity of each scope element is estimated by Subject Matter Experts (SMEs), including a level of uncertainty, relative to a specific reference system. When determining factors, complexity estimates for a scope element can be directly tied to the base system or chained together via comparable scope elements in a string of reference systems that ends with the base system. The SCORE analysis process is a growing multi-organizational Nuclear Security Enterprise (NSE) effort, under the management of the NA-12 led Enterprise Modeling and Analysis Consortium (EMAC). Historically, it has provided the data elicitation, integration, and computation needed to support the out-year Life Extension Program (LEP) cost estimates included in the Stockpile Stewardship Management Plan (SSMP).

12 CFR 564.1 - Authority, purpose, and scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Authority, purpose, and scope. 564.1 Section 564.1 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY APPRAISALS § 564.1 Authority, purpose, and scope. (a) Authority. This part is issued by the Office of Thrift Supervision (“OTS...

10 CFR 2.1000 - Scope of subpart J.

Science.gov (United States)

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Scope of subpart J. 2.1000 Section 2.1000 Energy NUCLEAR REGULATORY COMMISSION RULES OF PRACTICE FOR DOMESTIC LICENSING PROCEEDINGS AND ISSUANCE OF ORDERS Procedures... Geologic Repository § 2.1000 Scope of subpart J. The rules in this subpart, together with the rules in...

7 CFR 246.1 - General purpose and scope.

Science.gov (United States)

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false General purpose and scope. 246.1 Section 246.1... General § 246.1 General purpose and scope. This part announces regulations under which the Secretary of... health by reason of inadequate nutrition or health care, or both. The purpose of the Program is to...

32 CFR 537.16 - Scope for maritime claims.

Science.gov (United States)

2010-07-01

... 32 National Defense 3 2010-07-01 2010-07-01 true Scope for maritime claims. 537.16 Section 537.16... BEHALF OF THE UNITED STATES § 537.16 Scope for maritime claims. The Army Maritime Claims Settlement Act... claims for damage to: (1) DA-accountable properties of a kind that are within the federal maritime...

32 CFR 536.119 - Scope for maritime claims.

Science.gov (United States)

2010-07-01

... 32 National Defense 3 2010-07-01 2010-07-01 true Scope for maritime claims. 536.119 Section 536... CLAIMS AGAINST THE UNITED STATES Maritime Claims § 536.119 Scope for maritime claims. The AMCSA applies...) Damage that is maritime in nature and caused by tortious conduct of U.S. military personnel or federal...

EIA scoping in England and Wales: Practitioner approaches, perspectives and constraints

International Nuclear Information System (INIS)

Wood, Graham; Glasson, John; Becker, Julia

2006-01-01

Scoping plays a critical role in shaping the nature and extent of the environmental information subsequently contained in an Environmental Impact Statement (EIS), yet it has been identified as an area of weakness in practice () and remains a poorly understood and under-researched component of EIA. This paper provides a detailed empirical investigation and assessment of recent scoping activity in England and Wales, in the context of evolving European Union (EU) regulations. Conceptual and contextual issues associated with scoping are outlined prior to the presentation of key findings, including: approaches to scoping; the assessment of significance; characteristics and influence of consultation; and perceived constraints to scoping. The paper concludes with an overview of findings, possible explanatory factors, and recommendations for future practice

22 CFR 18.1 - Scope.

Science.gov (United States)

2010-04-01

... § 18.1 Scope. This part contains rules governing disciplinary action against a former officer or... employment conflict of interest prohibitions. Such disciplinary action may include prohibition from practice...

10 CFR 431.291 - Scope.

Science.gov (United States)

2010-01-01

... Refrigerated Bottled or Canned Beverage Vending Machines § 431.291 Scope. This subpart specifies test procedures for certain commercial refrigerated bottled or canned beverage vending machines, pursuant to part...

Energy Data Base: Subject categories and scope: A reference manual

International Nuclear Information System (INIS)

Grissom, M.C.

1987-04-01

The subject scope of the Energy Data Base (EDB) is defined, encompassing all technological aspects of energy production, conversion, and efficient utilization, and the economic, social, and political aspects as well. Coverage also includes the basic sciences as applicable. The subject areas within the scope of EDB are defined and hierarchically numbered, and scope notes are provided to define the extent of interest in certain areas, particularly areas of basic research

Current information on the scope and nature of child sexual abuse.

Science.gov (United States)

Finkelhor, D

1994-01-01

Approximately 150,000 confirmed cases of child sexual abuse were reported to child welfare authorities in the United States during 1993. This number represents about 15% of the more than one million confirmed cases of all child abuse and neglect. But the true scope of this problem is better reflected in retrospective surveys of adults, and this article summarizes data from 19 of these surveys. Considerable evidence exists to show that at least 20% of American women and 5% to 10% of American men experienced some form of sexual abuse as children. The rates are somewhat lower among people born before World War II, but there is little evidence of a dramatic increase for recent generations. The studies provide little evidence that race or socioeconomic circumstances are major risk factors. They do show elevated risk for children who experienced parental inadequacy, unavailability, conflict, harsh punishment, and emotional deprivation. Adult retrospective studies are also good sources of information about the characteristics of abuse. Most sexual abuse is committed by men (90%) and by persons known to the child (70% to 90%), with family members constituting one-third to one-half of the perpetrators against girls and 10% to 20% of the perpetrators against boys. Family members constitute a higher percentage of the perpetrators in child protective agency cases because the mandate of these agencies generally precludes their involvement in extrafamily abuse. Around 20% to 25% of child sexual abuse cases involve penetration or oral-genital contact. The peak age of vulnerability is between 7 and 13. Studies of the criminal justice processing of sexual abusers suggest that, compared with other violent criminals, slightly fewer are prosecuted, but of those prosecuted, slightly more are convicted. Studies conducted in the 1980s also showed that, once convicted, relatively few sexual abusers receive sentences longer than one year, while 32% to 46% serve no jail time. Overall, there

48 CFR 237.7100 - Scope.

Science.gov (United States)

2010-10-01

... DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Laundry and Dry Cleaning Services 237.7100 Scope. This subpart— (a) Applies to contracts for laundry and dry cleaning services within the United...

14 CFR 385.3 - Scope of staff action.

Science.gov (United States)

2010-01-01

...) ORGANIZATION STAFF ASSIGNMENTS AND REVIEW OF ACTION UNDER ASSIGNMENTS General Provisions § 385.3 Scope of staff... manner as if no assignment had been made (see § 385.5). In such proceedings, each staff member may... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Scope of staff action. 385.3 Section 385.3...

12 CFR 1510.1 - Authority, purpose, and scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Authority, purpose, and scope. 1510.1 Section 1510.1 Banks and Banking DEPARTMENT OF THE TREASURY RESOLUTION FUNDING CORPORATION RESOLUTION FUNDING... section 21B(l) of the Federal Home Loan Bank Act (12 U.S.C. 1441b(l)). (b) Purpose and scope. The purpose...

10 CFR 2.700 - Scope of subpart G.

Science.gov (United States)

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Scope of subpart G. 2.700 Section 2.700 Energy NUCLEAR... Formal Adjudications § 2.700 Scope of subpart G. The provisions of this subpart apply to and supplement... authorization for high-level radioactive waste repository noticed under §§ 2.101(f)(8) or 2.105(a)(5...

Double-Scope Peroral Endoscopic Myotomy (POEM for Esophageal Achalasia: The First Trial of a New Double-Scope POEM

Directory of Open Access Journals (Sweden)

Hee Jin Hong

2016-07-01

Full Text Available With the accumulation of clinical trials demonstrating its efficacy and safety, peroral endoscopic myotomy (POEM has emerged as a less invasive treatment option for esophageal achalasia compared with laparoscopic Heller myotomy. However, the difficulty in determining the exact extent of myotomy, a critical factor associated with the success and safety of the procedure, remains a limitation. Although the various endoscopic landmarks and ancillary techniques have been applied, none of these has been proven sufficient. As a solution for this limitation, the double-scope POEM technique with a second endoscope to assure the exact length of the submucosal tunnel has been applied since 2014. Before double-scope POEM was introduced, the second endoscope was applied only to confirm the accuracy of the procedure. In the present study, we performed double-scope POEM in the treatment of esophageal achalasia through a novel procedure of simultaneous application of the second endoscope to assist in the conventional POEM procedure.

Current Activities of the Joint Council on Economic Education.

Science.gov (United States)

Highsmith, Robert J.

1987-01-01

Reviews current activities of the Joint Council, among them, a researcher training institute, a new K-12 economic education scope and sequence document, a junior high level test of economic knowledge, an instructional package for advanced placement classes, a textbook conference, a project to help teachers of students who work with at-risk…

48 CFR 22.1500 - Scope.

Science.gov (United States)

2010-10-01

... APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Prohibition of Acquisition of Products Produced by Forced or Indentured Child Labor 22.1500 Scope. This subpart applies to acquisitions of supplies that exceed...

Physical activity promotion in physiotherapy practice: a systematic scoping review of a decade of literature.

Science.gov (United States)

Lowe, Anna; Gee, Melanie; McLean, Sionnadh; Littlewood, Chris; Lindsay, Carolyn; Everett, Simon

2018-01-01

The health benefits of physical activity (PA) have been extensively documented. Globally PA levels are low with only a small proportion of the population reaching recommended levels. Insufficient PA is seen as a major public health problem with high cost to society. Physiotherapists work with people to manage long-term conditions and are well placed to deliver individual interventions to increase PA. Despite this, little is known about the evidence that exists in this field. This scoping review comprises a comprehensive search of key databases using predetermined search terms. This is supplemented with a parallel search that incorporated novel social media strands. In line with current guidance, a robust screening process took place using agreed inclusion and exclusion criteria. 31 studies met the inclusion criteria. The number of studies published annually increased over the decade. Ireland and USA yielded the largest number of publications with only 1 study from the UK. The target populations included physiotherapists and service users from a range of clinical populations. The studies were mainly quantitative and observational in design with a predominance of studies that scoped attitudes, perceptions, barriers and current practice. This reconnaissance has shown the state of the evidence to be sparse and disparate. However, the sharp rise in published work in recent years is encouraging. The predominance of scoping studies and the clear social, economic and political drivers for change in this area highlights a need for more pragmatic, interventional studies that can inform clinical practice. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Exploring extended scope of practice in dietetics: A systems approach.

Science.gov (United States)

Ryan, Dominique; Pelly, Fiona; Purcell, Elizabeth

2017-09-01

The aim of this study was to explore health professionals' perceptions of an extended scope of a practice clinic, and develop a framework using a systems approach to facilitate extended scope models across various health settings. A qualitative investigation using semi-structured interviews with four health professionals involved in an extended scope dietitian-led gastroenterology clinic in a hospital in regional Queensland was conducted. A case study design was utilised to investigate interviewees' perceptions of the clinic. Participants were conveniently, purposively sampled. Transcript analysis involved a descriptive analytical approach. Interviewee responses were coded and categorised into themes, and investigator triangulation was used to ensure consistency between individual analyses. A secondary interpretative analysis was conducted where relationships between key themes were mapped to the Systems Engineering Initiative for Patient Safety work system model. Interviewees identified various factors as vital inputs to the work system. These were categorised into the four key elements: stakeholder support, resources, planning and the dietitian. Clinic outcomes were categorised into the impact on four key groups: patients, the dietitian, the multidisciplinary team and the health system. Mapping of the relationships between inputs and outcomes resulted in an implementation framework for extended scope of practice. Extended scope of practice in dietetics may provide positive outcomes for various stakeholders. However, further development of extended scope roles for dietitians requires increased advocacy and support from governments, professional bodies, training institutions and dietitians. We have developed an implementation framework which can be utilised by health professionals interested in embracing an extended scope model of care. © 2016 Dietitians Association of Australia.

Adoption of e-health technology by physicians: a scoping review

Directory of Open Access Journals (Sweden)

de Grood C

2016-08-01

Full Text Available Chloe de Grood,1 Aida Raissi,2 Yoojin Kwon,3 Maria Jose Santana1 1Department of Community Health Sciences, W21C Research and Innovation Centre, University of Calgary, Calgary, 2University of Alberta, Edmonton, AB, 3Toronto Public Library, Toronto, ON, Canada Objective: The goal of this scoping review was to summarize the current literature identifying barriers and opportunities that facilitate adoption of e-health technology by physicians.Design: Scoping review.Setting: MEDLINE, EMBASE, and PsycINFO databases as provided by Ovid were searched from their inception to July 2015. Studies captured by the search strategy were screened by two reviewers and included if the focus was on barriers and facilitators of e-health technology adoption by physicians.Results: Full-text screening yielded 74 studies to be included in the scoping review. Within those studies, eleven themes were identified, including cost and liability issues, unwillingness to use e-health technology, and training and support.Conclusion: Cost and liability issues, unwillingness to use e-health technology, and training and support were the most frequently mentioned barriers and facilitators to the adoption of e-health technology. Government-level payment incentives and privacy laws to protect health information may be the key to overcome cost and liability issues. The adoption of e-health technology may be facilitated by tailoring to the individual physician’s knowledge of the e-health technology and the use of follow-up sessions for physicians and on-site experts to support their use of the e-health technology. To ensure the effective uptake of e-health technologies, physician perspectives need to be considered in creating an environment that enables the adoption of e-health strategies. Keywords: medical informatics, electronic medical records, diffusion of innovation, attitude of health personnel, information seeking behavior

Automated diagnostics scoping study. Final report

Energy Technology Data Exchange (ETDEWEB)

Quadrel, R.W.; Lash, T.A.

1994-06-01

The objective of the Automated Diagnostics Scoping Study was to investigate the needs for diagnostics in building operation and to examine some of the current technologies in automated diagnostics that can address these needs. The study was conducted in two parts. In the needs analysis, the authors interviewed facility managers and engineers at five building sites. In the technology survey, they collected published information on automated diagnostic technologies in commercial and military applications as well as on technologies currently under research. The following describe key areas that the authors identify for the research, development, and deployment of automated diagnostic technologies: tools and techniques to aid diagnosis during building commissioning, especially those that address issues arising from integrating building systems and diagnosing multiple simultaneous faults; technologies to aid diagnosis for systems and components that are unmonitored or unalarmed; automated capabilities to assist cause-and-effect exploration during diagnosis; inexpensive, reliable sensors, especially those that expand the current range of sensory input; technologies that aid predictive diagnosis through trend analysis; integration of simulation and optimization tools with building automation systems to optimize control strategies and energy performance; integration of diagnostic, control, and preventive maintenance technologies. By relating existing technologies to perceived and actual needs, the authors reached some conclusions about the opportunities for automated diagnostics in building operation. Some of a building operator`s needs can be satisfied by off-the-shelf hardware and software. Other needs are not so easily satisfied, suggesting directions for future research. Their conclusions and suggestions are offered in the final section of this study.

Modeling requirements for full-scope reactor simulators of fission-product transport during severe accidents

International Nuclear Information System (INIS)

Ellison, P.G.; Monson, P.R.; Mitchell, H.A.

1990-01-01

This paper describes in the needs and requirements to properly and efficiently model fission product transport on full scope reactor simulators. Current LWR simulators can be easily adapted to model severe accident phenomena and the transport of radionuclides. Once adapted these simulators can be used as a training tool during operator training exercises for training on severe accident guidelines, for training on containment venting procedures, or as training tool during site wide emergency training exercises

Site, Sector, Scope: Mapping the Epistemological Landscape of Health Humanities.

Science.gov (United States)

Charise, Andrea

2017-12-01

This essay presents a critical appraisal of the current state of baccalaureate Health Humanities, with a special focus on the contextual differences currently influencing the implementation of this field in Canada and, to a lesser extent, the United States and United Kingdom. I argue that the epistemological bedrock of Health Humanities goes beyond that generated by its written texts to include three external factors that are especially pertinent to undergraduate education: site (the setting of Health Humanities education), sector (the disciplinary eligibility for funding) and scope (the critical engagement with a program's local context alongside an emergent "core" of Health Humanities knowledge, learning, and practice). Drawing largely from the Canadian context, I discuss how these differences can inform or obstruct this field's development, and offer preliminary recommendations for encouraging the growth of baccalaureate Health Humanities-in Canada and elsewhere-in light of these factors.

Methylation of Promoter Regions of Genes of the Human Intrauterine Renin Angiotensin System and Their Expression

Directory of Open Access Journals (Sweden)

Shane D. Sykes

2015-01-01

Full Text Available The intrauterine renin angiotensin system (RAS is implicated in placentation and labour onset. Here we investigate whether promoter methylation of RAS genes changes with gestation or labour and if it affects gene expression. Early gestation amnion and placenta were studied, as were term amnion, decidua, and placenta collected before labour (at elective caesarean section or after spontaneous labour and delivery. The expression and degree of methylation of the prorenin receptor (ATP6AP2, angiotensin converting enzyme (ACE, angiotensin II type 1 receptor (AGTR1, and two proteases that can activate prorenin (kallikrein, KLK1, and cathepsin D, CTSD were measured by qPCR and a DNA methylation array. There was no effect of gestation or labour on the methylation of RAS genes and CTSD. Amnion and decidua displayed strong correlations between the percent hypermethylation of RAS genes and CTSD, suggestive of global methylation. There were no correlations between the degree of methylation and mRNA abundance of any genes studied. KLK1 was the most methylated gene and the proportion of hypermethylated KLK1 alleles was lower in placenta than decidua. The presence of intermediate methylated alleles of KLK1 in early gestation placenta and in amnion after labour suggests that KLK1 methylation is uniquely dynamic in these tissues.

Development, concept and scope of copyright protection in Nigeria ...

African Journals Online (AJOL)

Development, concept and scope of copyright protection in Nigeria: an overview. ... Nnamdi Azikiwe University Journal of International Law and Jurisprudence ... This forms the aim of this paper which focuses essentially on basic issues relating to the development, concept and the scope of protection afforded copyright in ...

40 CFR 73.50 - Scope and submission of transfers.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Scope and submission of transfers. 73.50 Section 73.50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Allowance Transfers § 73.50 Scope and submission of transfers. (a...

Okul Öncesi Eğitimde High scope Yaklaşımı

OpenAIRE

BİLALOĞLU, Arş. Gör. Raziye GÜNAY

2013-01-01

In this paper information regarding High Scope approach its goals its basic principles and how to implement High Scope approach in early childhood education was presented Moreover in this paper roles of the teacher and children in High Scope as well as how the learning environment should be designed are explained In conclusion it is thought that without giving up the preschool program of the Ministry of National Education and integrating it with the basic principles of High Scope ...

Development of a safety case for the use of current limiting devices to manage short circuit currents on electrical distribution networks. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

2004-07-01

The original objective of this study was to review the safety issues associated with the use of current limiting devices and to write a risk assessment in accordance with good practice. But, when legislative procedures became apparent, the scope was changed to include involvement with the HSE, the DTI and Ofgem. It turned out that it would have been very difficult to write a safety case that would satisfy all of the agencies, or a risk assessment that would cover all applications. The scope of the study was therefore changed to focus on how the existing barriers should be tackled and the implications of the existing legislation. The approach to the study is described; it included reviews of background information and literature, questionnaires to manufacturers, a review of the reliability and hazards of the devices, and a review of UK safety legislation. The Final Report describes all this and includes discussion on the consequences of failure of fault current limiting devices, control measures which could be used to minimise risk, and recommendations for a way forward.

E-textiles in Clinical Rehabilitation: A Scoping Review

Directory of Open Access Journals (Sweden)

Amanda Fleury

2015-02-01

Full Text Available Electronic textiles have potential for many practical uses in clinical rehabilitation. This scoping review appraises recent and emerging developments of textile-based sensors with applications to rehabilitation. Contributions published from 2009 to 2013 are appraised with a specific focus on the measured physiological or biomechanical phenomenon, current measurement practices, textile innovations, and their merits and limitations. While fabric-based signal quality and sensor integration have advanced considerably, overall system integration (including circuitry and power has not been fully realized. Validation against clinical gold standards is inconsistent at best, and feasibility with clinical populations remains to be demonstrated. The overwhelming focus of research and development has been on remote sensing but the opportunity for textile-mediated feedback to the wearer remains unexplored. Recommendations for future research are provided.

Scope and closures

CERN Document Server

Simpson, Kyle

2014-01-01

No matter how much experience you have with JavaScript, odds are you don’t fully understand the language. This concise yet in-depth guide takes you inside scope and closures, two core concepts you need to know to become a more efficient and effective JavaScript programmer. You’ll learn how and why they work, and how an understanding of closures can be a powerful part of your development skillset.

The Influence of Affective States Varying in Motivational Intensity on Cognitive Scope

Directory of Open Access Journals (Sweden)

Eddie eHarmon-Jones

2012-09-01

Full Text Available We review a program of research that has suggested that affective states high in motivationally intensity (e.g., enthusiasm, disgust narrow cognitive scope, whereas affective states low in motivationally intensity (e.g., joy, sadness broaden cognitive scope. Further supporting this interpretation, indices of brain activations, derived from human electroencephalography, suggest that the motivational intensity of the affective state predicts the narrowing of cognitive scope. Finally, research suggests that the relationship between emotive intensity and cognitive scope is bi-directional, such that manipulated changes in cognitive scope influence early brain activations associated with emotive intensity. In the end, the review highlights how emotion can impair and improve certain cognitive processes.

United Kingdom. Report 3 [Marine Radioecology. Current Research and Future Scope

International Nuclear Information System (INIS)

Preston, A.

1967-01-01

Present research programmes: There are two current programmes, one in the Irish Sea (fission product distribution in coastal water environments) and one in the Blackwater Estuary - North Sea (effects of discharge of neutron activation radionuclides, e.g, 65 Zn, 51 Cr, 60 Co, 54 Mn, on an estuarine environment)

Radar Plan Position Indicator Scope

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Radar Plan Position Indicator Scope is the collection of weather radar imagery for the period prior to the beginning of the Next Generation Radar (NEXRAD) system...

Nurse and midwifery education and intimate partner violence: a scoping review.

Science.gov (United States)

Crombie, Nerissa; Hooker, Leesa; Reisenhofer, Sonia

2017-08-01

This scoping review aims to identify the scope of current literature considering nurse/midwife educational practices in the areas of intimate partner violence to inform future nursing/midwifery educational policy and practice. Intimate partner violence is a global issue affecting a significant portion of the community. Healthcare professionals including nurses/midwives in hospital- and community-based environments are likely to encounter affected women and need educational strategies that support best practice and promote positive outcomes for abused women and their families. Scoping review of relevant literature from January 2000 to July 2015. Search of databases: CINHAL, MEDLINE, EMBASE, PROQUEST Central and COCHRANE Library. Reference lists from included articles were searched for relevant literature as were several grey literature sources. This review demonstrates low levels of undergraduate or postregistration intimate partner violence education for nursing/midwifery staff and students. Existing intimate partner violence education strategies are varied in implementation, method and content. Outcomes of these educational programmes are not always rigorously evaluated for staff or client-based outcomes. Further research is needed to evaluate existing intimate partner violence education programmes for nurses/midwives and identify the most effective strategies to promote improved clinical practice and outcomes for abused women and their families. Intimate partner violence has a significant social and public health impact. The World Health Organization has identified the need to ensure that healthcare professionals are adequately trained to meet the needs of abused women. Intimate partner violence education programmes, commencing at undergraduate studies for nurses/midwives, need to be implemented with rigorously evaluated programmes to ensure they meet identified objectives, promote best practice and improve care for abused women. © 2016 John Wiley & Sons Ltd.

42 CFR 495.304 - Medicaid provider scope and eligibility.

Science.gov (United States)

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false Medicaid provider scope and eligibility. 495.304 Section 495.304 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.304 Medicaid provider scope and...

Effective Dropout Prevention Strategies Developed by the High/Scope Educational Research Foundation.

Science.gov (United States)

Stellar, Arthur

2002-01-01

Introduces a collection of papers that address the High/Scope Foundation's approach to risk reduction and dropout prevention. Examines High/Scope's history and describes various High/Scope efforts (e.g., the Michigan School Readiness Program Evaluation, preschool and elementary curriculum development and training, movement and music curriculum…

Using drawings to explore patients’ perceptions of their illness: a scoping review

Directory of Open Access Journals (Sweden)

Cheung MMY

2016-11-01

Full Text Available Melissa Mei Yin Cheung, Bandana Saini, Lorraine Smith Faculty of Pharmacy, The University of Sydney, Camperdown, NSW, Australia Background: An emerging approach for investigating patient perspectives of their illness is the use of drawings. Objective: This scoping review consolidates findings from current literature regarding the use of drawings to explore patients’ perceptions and experiences of their illness and treatment. Methods: Electronic databases (Medline, PubMed, Embase, PsychINFO, Cinahl, Art Index and Scopus and reference lists were searched to identify published English language studies using participant-generated drawings to explore adults’ perceptions and experiences of their illness and treatment. Using the scoping methodological framework, data were analyzed with respect to each study’s design, key findings and implications. Results: Thirty-two studies were identified and these reflected diversities in both health conditions and methods of data collection and analysis. Participants’ drawings revealed new, insightful knowledge about patients’ perceptions, beliefs and experiences of their condition and were associated with clinical and psychological markers of health. Drawing was a powerful adjunct to traditional data collection approaches, and demonstrated potential benefits for participants. This review provides detailed insights and guidance on the use of drawings in research and clinical practice. Conclusion: Drawing is a novel and potentially valuable technique for exploring patients’ perceptions and experiences about their illness and treatment. Advancing the methodology and applicability of drawings in this area will assist in the future development of this technique, with benefits for the patient, researcher and health care professional alike. Keywords: scoping review, drawing, illness perceptions, patient experience 

41 CFR 105-1.000-50 - Scope of part.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Scope of part. 105-1.000-50 Section 105-1.000-50 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION § 105-1.000-50 Scope of part...

12 CFR 563f.1 - Authority, purpose, and scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Authority, purpose, and scope. 563f.1 Section... INTERLOCKS § 563f.1 Authority, purpose, and scope. (a) Authority. This part is issued under the provisions of... generally prohibiting a management official from serving two nonaffiliated depository organizations in...

Literacy Teaching Aids from High/Scope Educational Research Foundation

Science.gov (United States)

Science Activities: Classroom Projects and Curriculum Ideas, 2005

2005-01-01

High/Scope's approach to education is a blend of Jean Piaget's constructivist theory of child development and the best of traditional teacher experience. The High/Scope approach is about helping students gain knowledge and skills in important content areas, such as language and literacy, initiative and social relations, movement, music, and…

12 CFR 6.20 - Scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Scope. 6.20 Section 6.20 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY PROMPT CORRECTIVE ACTION Directives To Take Prompt... part. ...

48 CFR 1804.470-1 - Scope.

Science.gov (United States)

2010-10-01

... ADMINISTRATIVE MATTERS Safeguarding Classified Information Within Industry 1804.470-1 Scope. This section... administration of hardware, software, firmware, computer systems, networks, and telecommunications systems. [72...

12 CFR 27.1 - Scope and OMB control number.

Science.gov (United States)

2010-01-01

... Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY FAIR HOUSING HOME LOAN DATA SYSTEM § 27.1 Scope and OMB control number. (a) Scope. This part applies to the activities of national... information requirements contained in this part were approved by the Office of Management and Budget under OMB...

Automated scoping methodology for liquid metal natural circulation small reactor

International Nuclear Information System (INIS)

Son, Hyung M.; Suh, Kune Y.

2014-01-01

Highlights: • Automated scoping methodology for natural circulation small modular reactor is developed. • In-house code is developed to carry out system analysis and core geometry generation during scoping. • Adjustment relations are obtained to correct the critical core geometry out of diffusion theory. • Optimized design specification is found using objective function value. • Convex hull volume is utilized to quantify the impact of different constraints on the scope range. - Abstract: A novel scoping method is proposed that can automatically generate design variable range of the natural circulation driven liquid metal cooled small reactor. From performance requirements based upon Generation IV system roadmap, appropriate structure materials are selected and engineering constraints are compiled based upon literature. Utilizing ASME codes and standards, appropriate geometric sizing criteria on constituting components are developed to ensure integrity of the system during its lifetime. In-house one dimensional thermo-hydraulic system analysis code is developed based upon momentum integral model and finite element methods to deal with non-uniform descritization of temperature nodes for convection and thermal diffusion equation of liquid metal coolant. In order to quickly generate critical core dimensions out of given unit cell information, an adjustment relation that relates the critical geometry estimated from one-group diffusion and that from MCNP code is constructed and utilized throughout the process. For the selected unit cell dimension ranges, burnup calculations are carried out to check the cores can generate energy over the reactor lifetime. Utilizing random method, sizing criteria, and in-house analysis codes, an automated scoping methodology is developed. The methodology is applied to nitride fueled integral type lead cooled natural circulation reactor concept to generate design scopes which satisfies given constraints. Three dimensional convex

The role of Facilities in Engaging and Informing the Public of EarthScope Science

Science.gov (United States)

Charlevoix, D. J.; Taber, J. J.; Berg, M.; Dorr, P. M.; McQuillan, P.; Olds, S. E.

2013-12-01

The IRIS and UNAVCO facilities play an important role in support of EarthScope through joint and independent education and outreach activities. These activities are focused on providing data and data products to a wide range of audiences, disseminating EarthScope science results through formal and informal venues, and informing the public of the broader impacts of EarthScope. The facilities are particularly well-suited for sustained engagement of multiple audiences over the decade-long course of EarthScope. One such example of a long-term effort was the Transportable Array student siting program, where over an 8 year period, students from about 55 institutions across the US and Canada conducted site reconnaissance and talked to landowners about EarthScope. Another activity focused on students was the development of a student intern program to support field engineering efforts during the construction of the Plate Boundary Observatory. Other ongoing activities include developing and maintaining relationships with media representatives and annual training of National Parks staff throughout the western U.S. The UNAVCO-IRIS partnership has been particularly valuable for EarthScope-related activities, where UNAVCO and IRIS work closely with the EarthScope National Office (ESNO) to bring EarthScope science to national, regional and local audiences within the EarthScope footprint. Collaborations have ranged across each group's products and services, including: EarthScope-focused teacher workshops, participation in EarthScope interpretive workshops for informal educators (led by ESNO), development of content for the IRIS Active Earth Monitor, preparing PBO-, USArray- and EarthScope-focused materials on topics such as Episodic Tremor and Slip for wider distribution through print, web, and mobile information technologies, and organizing research experiences for undergraduates on EarthScope-related topics. Other collaborations have focused on social media, and the development

Scoping Study: Networked Microgrids.

Energy Technology Data Exchange (ETDEWEB)

Trinklei, Eddy; Parker, Gordon; Weaver, Wayne; Robinett, Rush; Babe Gauchia, Lucia; Ten, Chee-Wooi; Bower, Ward; Glover, Steven F.; Bukowski, Steve

2014-10-01

This report presents a scoping study for networked microgrids which are defined as "Interoperable groups of multiple Advanced Microgrids that become an integral part of the electricity grid while providing enhanced resiliency through self-healing, aggregated ancillary services, and real-time communication." They result in optimal electrical system configurations and controls whether grid-connected or in islanded modes and enable high penetrations of distributed and renewable energy resources. The vision for the purpose of this document is: "Networked microgrids seamlessly integrate with the electricity grid or other Electric Power Sources (EPS) providing cost effective, high quality, reliable, resilient, self-healing power delivery systems." Scoping Study: Networked Microgrids September 4, 2014 Eddy Trinklein, Michigan Technological University Gordon Parker, Michigan Technological University Wayne Weaver, Michigan Technological University Rush Robinett, Michigan Technological University Lucia Gauchia Babe, Michigan Technological University Chee-Wooi Ten, Michigan Technological University Ward Bower, Ward Bower Innovations LLC Steve Glover, Sandia National Laboratories Steve Bukowski, Sandia National Laboratories Prepared by Michigan Technological University Houghton, Michigan 49931 Michigan Technological University

7 CFR 610.2 - Scope.

Science.gov (United States)

2010-01-01

... conservation activities and programs. NRCS works with individuals, groups, and units of government to help them... the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE CONSERVATION OPERATIONS TECHNICAL ASSISTANCE Conservation Operations § 610.2 Scope. (a...

The scope and control of attention: Sources of variance in working memory capacity.

Science.gov (United States)

Chow, Michael; Conway, Andrew R A

2015-04-01

Working memory capacity is a strong positive predictor of many cognitive abilities, across various domains. The pattern of positive correlations across domains has been interpreted as evidence for a unitary source of inter-individual differences in behavior. However, recent work suggests that there are multiple sources of variance contributing to working memory capacity. The current study (N = 71) investigates individual differences in the scope and control of attention, in addition to the number and resolution of items maintained in working memory. Latent variable analyses indicate that the scope and control of attention reflect independent sources of variance and each account for unique variance in general intelligence. Also, estimates of the number of items maintained in working memory are consistent across tasks and related to general intelligence whereas estimates of resolution are task-dependent and not predictive of intelligence. These results provide insight into the structure of working memory, as well as intelligence, and raise new questions about the distinction between number and resolution in visual short-term memory.

28 CFR 90.60 - Scope.

Science.gov (United States)

2010-07-01

... domestic violence as a serious violation of criminal law. ... Administration DEPARTMENT OF JUSTICE (CONTINUED) VIOLENCE AGAINST WOMEN Arrest Policies in Domestic Violence Cases § 90.60 Scope. This subpart sets forth the statutory framework of the Violence Against Women Act's...

Editorial: A revised aims and scope for Landscape and Urban Planning: an international journal of landscape and design

Science.gov (United States)

Paul H. Gobster; Wei-Ning. Xiang

2012-01-01

From time to time it is appropriate for editors to revisit a journal's aims and scope and assess whether the statement accurately describes what the journal is about to current and potential participants in the journal community as well as to broader societies of concern. With the third editorship of Landscape and Urban Planning now having been involved in...

"High/Scope Supporting the Child, the Family, the Community": A Report of the Proceedings of the High/Scope Ireland Third Annual Conference, 12th October 2004, Newry, Northern Ireland

Science.gov (United States)

Peyton, Lynne

2005-01-01

The third annual High/Scope Ireland Conference provided a forum for speakers workshop leaders and delegates from across Ireland, the UK, USA, Europe and South Africa to share their experiences of High/Scope in action. Research demonstrates that long term benefits for High/Scope participants include increased literacy rates, school success and…

46 CFR 53.01-5 - Scope (modifies HG-100).

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Scope (modifies HG-100). 53.01-5 Section 53.01-5... General Requirements § 53.01-5 Scope (modifies HG-100). (a) The regulations in this part apply to steam... governing various types of pressure vessels and boilers. (b) Modifies HG-100. The requirements of Part HG of...

Increased oxidative stress in human fetal membranes overlying the cervix from term non-labouring and post labour deliveries.

Science.gov (United States)

Chai, M; Barker, G; Menon, R; Lappas, M

2012-08-01

Enzymatic breakdown of the collagen-rich extracellular matrix (ECM) that connects the amnion and chorion layers of the fetal membranes is one of the key events leading to rupture of membranes. Oxidant stress caused by increased formation of reactive oxygen species and/or reduced antioxidant capacity may predispose to membrane rupture, a major cause of preterm birth. The aim of this study was to determine the effect of human labour and supracervical (SC) apposition on antioxidant enzymes and 8-isoprostane (a marker of lipid peroxidation). To determine the effect of human labour on oxidative stress status, fetal membranes from the SC site (SCS) were collected from women at term Caesarean section (no labour), and from the site of membrane rupture (SOR) after spontaneous labour onset and delivery (post labour). To determine the effect of SC apposition on oxidative stress status, amnion was collected from the SCS and a distal site (DS) in women at term Caesarean section in the absence of labour. The release of 8-isoprostane was significantly higher in amnion from the SCS compared to DS, and in fetal membranes from the SOR compared to the SCS. Glutathione peroxidase (GPx) and superoxide dismutase (SOD) activity were lower in amnion from the SC compared to DS. SOD gene expression and enzyme activity were lower in fetal membranes after labour. There was no difference in expression or activity in catalase, GPx and glutathione reductase (GSR) between no labour and post labour fetal membranes. In primary amnion cells, SOD supplementation significantly augmented IL-1β induced MMP-9 expression and activity. In summary, non-labouring SC fetal membranes are characterised by reduced antioxidant enzyme activity when compared to distal membranes, and, as such, may be more susceptible to oxidative damage and thus membrane rupture. Copyright © 2012 Elsevier Ltd. All rights reserved.

44 CFR 206.343 - Scope.

Science.gov (United States)

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Scope. 206.343 Section 206.343 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND...; (2) Crisis counseling; (3) Disaster Legal services; and (4) Disaster unemployment assistance. ...

7 CFR 3015.60 - Scope.

Science.gov (United States)

2010-01-01

... Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE UNIFORM FEDERAL ASSISTANCE REGULATIONS Standards for Financial Management Systems § 3015.60 Scope. This subpart contains standards for financial management systems of recipients. No additional financial...

Multidominance, ellipsis, and quantifier scope

NARCIS (Netherlands)

Temmerman, Tanja Maria Hugo

2012-01-01

This dissertation provides a novel perspective on the interaction between quantifier scope and ellipsis. It presents a detailed investigation of the scopal interaction between English negative indefinites, modals, and quantified phrases in ellipsis. One of the crucial observations is that a negative

49 CFR 591.1 - Scope.

Science.gov (United States)

2010-10-01

... OF TRANSPORTATION (CONTINUED) IMPORTATION OF VEHICLES AND EQUIPMENT SUBJECT TO FEDERAL SAFETY, BUMPER AND THEFT PREVENTION STANDARDS § 591.1 Scope. This part establishes procedures governing the importation of motor vehicles and motor vehicle equipment subject to the Federal motor vehicle safety, bumper...

47 CFR 90.350 - Scope.

Science.gov (United States)

2010-10-01

... transportation infrastructure and to develop and implement the nation's intelligent transportation systems. It... SERVICES Intelligent Transportation Systems Radio Service § 90.350 Scope. The Intelligent Transportation... in the Intelligent Transportation Systems radio service are set forth in this subpart. [64 FR 66410...

Project scoping for lessons learnt to apply to the Celtic Seas marine sub-region

OpenAIRE

Twomey, Sarah; O'Mahony, Cathal

2013-01-01

This report involves a formal scoping exercise to identify lessons from a wide range of previous and current project and initiative experiences at the national, regional seas, European and global levels. An inventory of 77 projects and initiatives that are relevant with regard to the key activities proposed by the Celtic Seas Partnership has been compiled, as well as a short-list of 23 of the most pertinent projects, lessons learnt and contact names. This report has identified a number of syn...

Music-induced positive mood broadens the scope of auditory attention.

Science.gov (United States)

Putkinen, Vesa; Makkonen, Tommi; Eerola, Tuomas

2017-07-01

Previous studies indicate that positive mood broadens the scope of visual attention, which can manifest as heightened distractibility. We used event-related potentials (ERP) to investigate whether music-induced positive mood has comparable effects on selective attention in the auditory domain. Subjects listened to experimenter-selected happy, neutral or sad instrumental music and afterwards participated in a dichotic listening task. Distractor sounds in the unattended channel elicited responses related to early sound encoding (N1/MMN) and bottom-up attention capture (P3a) while target sounds in the attended channel elicited a response related to top-down-controlled processing of task-relevant stimuli (P3b). For the subjects in a happy mood, the N1/MMN responses to the distractor sounds were enlarged while the P3b elicited by the target sounds was diminished. Behaviorally, these subjects tended to show heightened error rates on target trials following the distractor sounds. Thus, the ERP and behavioral results indicate that the subjects in a happy mood allocated their attentional resources more diffusely across the attended and the to-be-ignored channels. Therefore, the current study extends previous research on the effects of mood on visual attention and indicates that even unfamiliar instrumental music can broaden the scope of auditory attention via its effects on mood. © The Author (2017). Published by Oxford University Press.

SCOPING SUMMARY FOR THE P-AREA OPERABLE UNIT

International Nuclear Information System (INIS)

Kupar, J; Sadika Baladi, S; Mark Amidon, M

2007-01-01

This scoping summary supports development of the combined Remedial Investigation (RI)/Baseline Risk Assessment (BRA)/Feasibility Study (FS) for the P-Area Operable Unit (PAOU), or Combined document, which will be submitted on or before 09/28/2007. The objective of this Feasibility Study scoping summary meeting is to agree on the likely response actions to be evaluated and developed as alternatives in the combined document and agree on the uncertainties identified and whether they have been adequately managed

SCOPING SUMMARY FOR THE P-AREA OPERABLE UNIT

Energy Technology Data Exchange (ETDEWEB)

Kupar, J; Sadika Baladi, S; Mark Amidon, M

2007-05-22

This scoping summary supports development of the combined Remedial Investigation (RI)/Baseline Risk Assessment (BRA)/Feasibility Study (FS) for the P-Area Operable Unit (PAOU), or Combined document, which will be submitted on or before 09/28/2007. The objective of this Feasibility Study scoping summary meeting is to agree on the likely response actions to be evaluated and developed as alternatives in the combined document and agree on the uncertainties identified and whether they have been adequately managed.

Sustainable childhood obesity prevention through community engagement (SCOPE) program: evaluation of the implementation phase.

Science.gov (United States)

McIntosh, Bonnie; Daly, Amelia; Mâsse, Louise C; Collet, Jean-Paul; Higgins, Joan Wharf; Naylor, Patti-Jean; Amed, Shazhan

2015-10-01

Childhood obesity rates are steadily rising. Sustainable Childhood Obesity Prevention Through Community Engagement (SCOPE) is a community-based participatory action research (PAR) program aimed at preventing childhood obesity. This study aimed to describe community perspectives on, and elicit feedback about, SCOPE's first phase of implementation in two pilot cities in British Columbia, Canada. A case study was implemented using interviews and questionnaires to obtain feedback about SCOPE from two groups: SCOPE coordinators and stakeholders (i.e., individuals and organizations that were a member of the community and engaged with SCOPE coordinators). Participants were recruited via email and (or) by telephone. Coordinators completed a telephone interview. Stakeholders completed a questionnaire and (or) a telephone interview. Thematic analysis was conducted. Participants included 2 coordinators and 15 stakeholders. Participants similarly interpreted SCOPE as a program focused on raising awareness about childhood obesity prevention, while engaging multiple community sectors. Overall, participants valued the program's role in facilitating networking and partnership development, providing evidence-based resources, technical expertise, and contributing funding. Participants felt that SCOPE is sustainable. However, participants felt that barriers to achieving healthy weights among children included those related to the built environment, and social, behavioral, and economic obstacles. Perspectives on factors that facilitated and acted as barriers to SCOPE's first phase of implementation were obtained from the SCOPE communities and may be used to enhance the sustainability of SCOPE and its applicability to other BC communities.

Scoping Review of the Zika Virus Literature.

Directory of Open Access Journals (Sweden)

Lisa A Waddell

Full Text Available The global primary literature on Zika virus (ZIKV (n = 233 studies and reports, up to March 1, 2016 has been compiled using a scoping review methodology to systematically identify and characterise the literature underpinning this broad topic using methods that are documented, updateable and reproducible. Our results indicate that more than half the primary literature on ZIKV has been published since 2011. The articles mainly covered three topic categories: epidemiology of ZIKV (surveillance and outbreak investigations 56.6% (132/233, pathogenesis of ZIKV (case symptoms/ outcomes and diagnosis 38.2% (89/233 and ZIKV studies (molecular characterisation and in vitro evaluation of the virus 18.5% (43/233. There has been little reported in the primary literature on ZIKV vectors (12/233, surveillance for ZIKV (13/233, diagnostic tests (12/233 and transmission (10/233. Three papers reported on ZIKV prevention/control strategies, one investigated knowledge and attitudes of health professionals and two vector mapping studies were reported. The majority of studies used observational study designs, 89.7% (209/233, of which 62/233 were case studies or case series, while fewer (24/233 used experimental study designs. Several knowledge gaps were identified by this review with respect to ZIKV epidemiology, the importance of potential non-human primates and other hosts in the transmission cycle, the burden of disease in humans, and complications related to human infection with ZIKV. Historically there has been little research on ZIKV; however, given its current spread through Australasia and the Americas, research resources are now being allocated to close many of the knowledge gaps identified in this scoping review. Future updates of this project will probably demonstrate enhanced evidence and understanding of ZIKV and its impact on public health.

Scoping Review of the Zika Virus Literature

Science.gov (United States)

2016-01-01

The global primary literature on Zika virus (ZIKV) (n = 233 studies and reports, up to March 1, 2016) has been compiled using a scoping review methodology to systematically identify and characterise the literature underpinning this broad topic using methods that are documented, updateable and reproducible. Our results indicate that more than half the primary literature on ZIKV has been published since 2011. The articles mainly covered three topic categories: epidemiology of ZIKV (surveillance and outbreak investigations) 56.6% (132/233), pathogenesis of ZIKV (case symptoms/ outcomes and diagnosis) 38.2% (89/233) and ZIKV studies (molecular characterisation and in vitro evaluation of the virus) 18.5% (43/233). There has been little reported in the primary literature on ZIKV vectors (12/233), surveillance for ZIKV (13/233), diagnostic tests (12/233) and transmission (10/233). Three papers reported on ZIKV prevention/control strategies, one investigated knowledge and attitudes of health professionals and two vector mapping studies were reported. The majority of studies used observational study designs, 89.7% (209/233), of which 62/233 were case studies or case series, while fewer (24/233) used experimental study designs. Several knowledge gaps were identified by this review with respect to ZIKV epidemiology, the importance of potential non-human primates and other hosts in the transmission cycle, the burden of disease in humans, and complications related to human infection with ZIKV. Historically there has been little research on ZIKV; however, given its current spread through Australasia and the Americas, research resources are now being allocated to close many of the knowledge gaps identified in this scoping review. Future updates of this project will probably demonstrate enhanced evidence and understanding of ZIKV and its impact on public health. PMID:27244249

42 CFR 423.150 - Scope.

Science.gov (United States)

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 423.150 Section 423.150 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Cost Control and Quality Improvement Requirements...

12 CFR 19.230 - Scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Scope. 19.230 Section 19.230 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY RULES OF PRACTICE AND PROCEDURE Order To Dismiss a... and part 6 of this chapter. ...

30 CFR 879.1 - Scope.

Science.gov (United States)

2010-07-01

... OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR ABANDONED MINE LAND RECLAMATION ACQUISITION, MANAGEMENT, AND DISPOSITION OF LANDS AND WATER § 879.1 Scope. This part establishes procedures for acquisition of eligible land and water resources for emergency abatement activities and...

23 CFR 1313.1 - Scope.

Science.gov (United States)

2010-04-01

... traffic safety problems resulting from individuals driving motor vehicles while under the influence of... TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION INCENTIVE GRANT CRITERIA FOR ALCOHOL-IMPAIRED DRIVING PREVENTION PROGRAMS § 1313.1 Scope. This part establishes criteria, in accordance with 23 U.S.C...

34 CFR 686.30 - Scope.

Science.gov (United States)

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false Scope. 686.30 Section 686.30 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION TEACHER EDUCATION ASSISTANCE FOR COLLEGE AND HIGHER EDUCATION (TEACH) GRANT PROGRAM...

28 CFR 92.7 - Scope.

Science.gov (United States)

2010-07-01

... Recruitment Program Guidelines § 92.7 Scope. (a) The Police Recruitment program offers funds to qualified... encountering problems throughout the police department application process shall receive counseling, tutorials, and other academic assistance as necessary to assist them in the application process of a police...

12 CFR 725.1 - Scope.

Science.gov (United States)

2010-01-01

... ADMINISTRATION CENTRAL LIQUIDITY FACILITY § 725.1 Scope. This part contains the regulations implementing the National Credit Union Central Liquidity Facility Act, subchapter III of the Federal Credit Union Act. The National Credit Union Administration Central Liquidity Facility is a mixed-ownership Government corporation...

34 CFR 668.161 - Scope and purpose (cash management rules).

Science.gov (United States)

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false Scope and purpose (cash management rules). 668.161... POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION STUDENT ASSISTANCE GENERAL PROVISIONS Cash Management § 668.161 Scope and purpose (cash management rules). (a) General. (1) This subpart establishes the rules and...

The dental public health implications of cosmetic dentistry: a scoping review of the literature.

Science.gov (United States)

Doughty, J; Lala, R; Marshman, Z

2016-09-01

The popularity of cosmetic surgery has seen a rapid increase recently, with the trend mirrored in dentistry. The Department of Health expressed concerns about the potential for biological and psychosocial harm of these cosmetic procedures. Furthermore, the dental public health implications (DPH) of the growing uptake of cosmetic dental procedures have not been explored. Conduct a scoping review to explore the DPH implications of cosmetic dentistry and identify gaps for future research. A fivestage scoping review was conducted of studies identified using the search terms cosmetic AND dentistry. Data from the studies meeting the inclusion criteria were extracted, collated and summarised into themes. Fifty-seven papers met the inclusion criteria (11 cross-sectional studies, 10 literature reviews and 36 opinion pieces). The DPH implications were summarised into five emergent themes: dento-legal and ethical, marketing, psychosocial, biological and workforce. These themes revealed patients' increased expectations, expanding commercialisation of the profession, psychological risks to vulnerable patients, the iatrogenic consequences of invasive cosmetic dental procedures and workforce implications of the current trends. The scoping review found that existing literature on cosmetic dentistry is predominately anecdotal - professional opinions and discussions. Despite this, our findings demonstrated workforce training and governance implications due to increased demand for cosmetic dentistry. Further empirical research is needed to understand the DPH implications of the increasing demand and uptake of cosmetic dental procedures to guide evidence-based policy to safeguard patients and improve the quality of dental services. Copyright© 2016 Dennis Barber Ltd

Scoping studies to reduce ICPP high-level radioactive waste volumes for final disposal

International Nuclear Information System (INIS)

Knecht, D.A.; Berreth, J.R.; Chipman, N.A.; Cole, H.S.; Geczi, L.S.; Kerr, W.B.; Staples, B.A.

1985-08-01

This report presents the results of scoping studies carried out to determine the feasibility of the following candidate options to reduce high-level waste volume: (1) low-fluoride, low-volume glass, (2) glass-ceramic and ceramic, (3) Modified Zirflex, (4) inerts removal by neutralization, and (5) modified Fluorinel processes. The results of the scoping studies show that the glass-ceramic/ceramic waste forms and neutralization process with potential HLW volume reductions ranging from 60 to 80% appear feasible, based on laboratory-scale tests. The presently used Fluorinel process modified by reducing HF usage also appears to be feasible and could result in up to a 10% potential volume reduction. If the current process start-up tests verify the practicality, reduced HF usage will be implemented. The low-volume glass and Modified Zirflex processes may also be feasible, based on laboratory tests, but would require significantly more process development and/or modifications and could result in only a 20 to 30% potential volume reduction. Based on these scoping studies, it is recommended that (1) the glass-ceramic/ceramic and neutralization processes be developed further, (2) reduced HF use for the Modified Fluorinel process be implemented as soon as practical and other options reducing chemical usage for criticality control be evaluated, (3) basic development for the glass process be continued as a back-up technology, and (4) laboratory-scale radioactive fuel dissolution testing for the Modified Zirflex process be completed with further process development discontinued unless needed in the future

Veda-scope: More comfortable than the bivalve speculum and cytologically equivalent.

Science.gov (United States)

Longmore, Peter G

2004-04-01

The aim of the present study was to confirm that the Veda-scope is equivalent to the bivalve speculum in the collection of endocervical cells, as confirmation of adequate cervical sampling for Pap smear testing. The study also aimed to assess the comfort level of the Veda-scope compared to the traditional bivalve speculum and the patient preference of the Veda-scope compared to the bivalve speculum. Multicentre, randomised, controlled crossover, cytologist blinded study. The total number of subjects enrolled in the study were 250. The number of evaluable subjects were 210. In primary efficacy analysis, no significant difference was seen between the presence or absence of endocervical cells in the smears using either the Veda-scope or the bivalve speculum. There was a high concordance level between the diagnosis assigned to each specimen of a paired sample, the diagnosis agreeing in 97.6% cases. The primary reason given by many women for avoidance of regular Pap smear examinations is the discomfort or pain experienced with sample collection with the bivalve speculum. In the present study, 92% of subjects indicated a preference for the Veda-scope for Pap smear collection, while only 8.4% preferred the bivalve speculum. Subject preference was also assessed with respect to how the subject rated the comfort level of her previous Pap smear. In subjects who rated their previous Pap smear as very comfortable or comfortable, 86% expressed a preference for the Veda-scope. This rose to 93% in subjects who rated their previous Pap smear as only tolerable. The results of the present study show that Pap smear collections with the Veda-scope are of equal quality to those collected with the bivalve speculum, with an equivalent diagnostic outcome. A very strong preference for the Veda-scope was shown by the women enrolled in the present study based on the comfort levels experienced with the two devices.

A scoping study for an environmental impact field programme in tidal current energy

Energy Technology Data Exchange (ETDEWEB)

NONE

2002-07-01

This report summarises the results of a study to identify the environmental impacts of tidal current energy with the aim of prioritising research. The background to the study is traced, and the interaction between tidal current energy technology and the marine environment, the modeling of the consequences of the environmental interactions, the quantification of the environmental impacts of key environmental interactions, and the formulation of a programme of research are discussed. Recommendations are given and research needs are highlighted.

Inflammatory Response of Human Gestational Membranes to Ureaplasma parvum Using a Novel Dual-Chamber Tissue Explant System.

Science.gov (United States)

Potts, Lauren C; Feng, Liping; Seed, Patrick C; Jayes, Friederike L; Kuchibhatla, Maragatha; Antczak, Brian; Nazzal, Matthew K; Murtha, Amy P

2016-05-01

Preterm premature rupture of membranes (PPROM) is often associated with intra-amniotic inflammation and infection. Current understanding of the pathogenesis of PPROM includes activation of pro-inflammatory cytokines and proteolytic enzymes leading to compromise of membrane integrity. The impact of exposure to bacterial pathogens, including Ureaplasma parvum, on gestational membranes is poorly understood. Our objective was to develop a dual-chamber system to characterize the inflammatory response of gestational membranes to U. parvum in a directional nature. Full-thickness human gestational membrane explants, with either choriodecidua or amnion oriented superiorly, were suspended between two washers in a cylindrical device, creating two distinct compartments. Brilliant green dye was introduced into the top chamber to assess the integrity of the system. Tissue viability was evaluated after 72 h using a colorimetric cell proliferation assay. Choriodecidua or amnion was exposed to three doses of U. parvum and incubated for 24 h. Following treatment, media from each compartment were used for quantification of U. parvum (quantitative PCR), interleukin (IL)-8 (enzyme-linked immunosorbent assay), and matrix metalloproteinase (MMP)-2 and MMP-9 activity (zymography). We observed that system integrity and explant viability were maintained over 72 h. Dose-dependent increases in recovered U. parvum, IL-8 concentration, and MMP-2 activity were detected in both compartments. Significant differences in IL-8 concentration and MMP-9 activity were found between the choriodecidua and amnion. This tissue explant system can be used to investigate the inflammatory consequences of directional bacterial exposure for gestational membranes and provides insight into the pathogenesis of PPROM and infectious complications of pregnancy. © 2016 by the Society for the Study of Reproduction, Inc.

Cost Efficiency and Returns to Scope in Italian Investment Firms

OpenAIRE

Marcello Basili; Fulvio Fontini

2005-01-01

This paper estimates cost efficiency and returns to scope of Italian investment firms during the period 1998-2002, following the stochastic frontier function approach. Results indicate a large inefficiency for Italian investment firms (with a high standard deviation across sample) and the absence of significant returns to scope

12 CFR 334.22 - Scope and duration of opt-out.

Science.gov (United States)

2010-01-01

... POLICY FAIR CREDIT REPORTING Affiliate Marketing § 334.22 Scope and duration of opt-out. (a) Scope of opt... relationship—(i) In general. If the consumer establishes a continuing relationship with you or your affiliate... continuing relationship or multiple continuing relationships that the consumer establishes with you or your...

42 CFR 410.36 - Medical supplies, appliances, and devices: Scope.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Medical supplies, appliances, and devices: Scope... Services § 410.36 Medical supplies, appliances, and devices: Scope. (a) Medicare Part B pays for the following medical supplies, appliances and devices: (1) Surgical dressings, and splints, casts, and other...

12 CFR 5.1 - Scope.

Science.gov (United States)

2010-01-01

... COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY RULES, POLICIES, AND PROCEDURES FOR CORPORATE ACTIVITIES § 5.1 Scope. This part establishes rules, policies and procedures of the Office of the Comptroller of the Currency (OCC) for corporate activities and transactions involving national banks. It contains...

15 CFR 325.1 - Scope.

Science.gov (United States)

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Scope. 325.1 Section 325.1 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE MISCELLANEOUS REGULATIONS EXPORT TRADE CERTIFICATES OF REVIEW § 325.1...

47 CFR 90.521 - Scope.

Science.gov (United States)

2010-10-01

... systems operating in the 763-775 MHz and 793-805 MHz frequency bands. It includes eligibility, operational... 47 Telecommunication 5 2010-10-01 2010-10-01 false Scope. 90.521 Section 90.521 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO...

12 CFR 370.1 - Scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Scope. 370.1 Section 370.1 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY TEMPORARY LIQUIDITY..., requirements, and other provisions related to participation in the FDIC's temporary liquidity guarantee program. ...

SCOPES: steganography with compression using permutation search

Science.gov (United States)

Boorboor, Sahar; Zolfaghari, Behrouz; Mozafari, Saadat Pour

2011-10-01

LSB (Least Significant Bit) is a widely used method for image steganography, which hides the secret message as a bit stream in LSBs of pixel bytes in the cover image. This paper proposes a variant of LSB named SCOPES that encodes and compresses the secret message while being hidden through storing addresses instead of message bytes. Reducing the length of the stored message improves the storage capacity and makes the stego image visually less suspicious to the third party. The main idea behind the SCOPES approach is dividing the message into 3-character segments, seeking each segment in the cover image and storing the address of the position containing the segment instead of the segment itself. In this approach, every permutation of the 3 bytes (if found) can be stored along with some extra bits indicating the permutation. In some rare cases the segment may not be found in the image and this can cause the message to be expanded by some overhead bits2 instead of being compressed. But experimental results show that SCOPES performs overlay better than traditional LSB even in the worst cases.

SunFast: A sun workstation based, fuel analysis scoping tool for pressurized water reactors

International Nuclear Information System (INIS)

Bohnhoff, W.J.

1991-05-01

The objective of this research was to develop a fuel cycle scoping program for light water reactors and implement the program on a workstation class computer. Nuclear fuel management problems are quite formidable due to the many fuel arrangement options available. Therefore, an engineer must perform multigroup diffusion calculations for a variety of different strategies in order to determine an optimum core reload. Standard fine mesh finite difference codes result in a considerable computational cost. A better approach is to build upon the proven reliability of currently available mainframe computer programs, and improve the engineering efficiency by taking advantage of the most useful characteristic of workstations: enhanced man/machine interaction. This dissertation contains a description of the methods and a user's guide for the interactive fuel cycle scoping program, SunFast. SunFast provides computational speed and accuracy of solution along with a synergetic coupling between the user and the machine. It should prove to be a valuable tool when extensive sets of similar calculations must be done at a low cost as is the case for assessing fuel management strategies. 40 refs

24 CFR 203.259a - Scope.

Science.gov (United States)

2010-04-01

... MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES SINGLE FAMILY MORTGAGE INSURANCE Contract Rights and Obligations Mortgage Insurance Premiums-in General § 203.259a Scope... Insurance Premiums—Periodic Payment ...

Academy of Nutrition and Dietetics: Scope of Practice for the Dietetic Technician, Registered.

Science.gov (United States)

2013-06-01

The Scope of Practice for the Dietetic Technician, Registered provides standards and tools to guide competence in performing nutrition and dietetics practice. Composed of statutory and individual components, the DTR's scope of practice is determined by state statute and the DTR's education, training, credentialing, and demonstrated and documented competence in practice. The Scope of Practice for the Dietetic Technician, Registered reflects the Academy's position on the DTR scope of practice and the essential technical assistance role of the DTR in providing safe timely person-centered care for the delivery of quality food and nutrition services.

Evaluation of full-scope simulator testing methods

International Nuclear Information System (INIS)

Feher, M.P.; Moray, N.; Senders, J.W.; Biron, K.

1995-03-01

This report discusses the use of full scope nuclear power plant simulators in licensing examinations for Unit First Operators of CANDU reactors. The existing literature is reviewed, and an annotated bibliography of the more important sources provided. Since existing methods are judged inadequate, conceptual bases for designing a system for licensing are discussed, and a method proposed which would make use of objective scoring methods based on data collection in full-scope simulators. A field trial of such a method is described. The practicality of such a method is critically discussed and possible advantages of subjective methods of evaluation considered. (author). 32 refs., 1 tab., 4 figs

Evaluation of full-scope simulator testing methods

Energy Technology Data Exchange (ETDEWEB)

Feher, M P; Moray, N; Senders, J W; Biron, K [Human Factors North Inc., Toronto, ON (Canada)

1995-03-01

This report discusses the use of full scope nuclear power plant simulators in licensing examinations for Unit First Operators of CANDU reactors. The existing literature is reviewed, and an annotated bibliography of the more important sources provided. Since existing methods are judged inadequate, conceptual bases for designing a system for licensing are discussed, and a method proposed which would make use of objective scoring methods based on data collection in full-scope simulators. A field trial of such a method is described. The practicality of such a method is critically discussed and possible advantages of subjective methods of evaluation considered. (author). 32 refs., 1 tab., 4 figs.

47 CFR 95.1101 - Scope.

Science.gov (United States)

2010-10-01

... SERVICES Wireless Medical Telemetry Service (WMTS) General Provisions § 95.1101 Scope. This subpart sets out the regulations governing the operation of Wireless Medical Telemetry Devices in the 608-614 MHz, 1395-1400 MHz, and 1427-1432 MHz frequency bands. See § 95.630 regarding permissible frequencies. [75...

42 CFR 423.452 - Scope.

Science.gov (United States)

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 423.452 Section 423.452 Public Health... PROGRAM VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Coordination of Part D Plans With Other Prescription...; establishes waivers for MA-PD plans, employer-sponsored group prescription drug plans, cost plans, and PACE...

12 CFR 263.400 - Scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Scope. 263.400 Section 263.400 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM RULES OF PRACTICE FOR HEARINGS Removal, Suspension, and Debarment of Accountants From Performing Audit Services...

49 CFR 545.1 - Scope.

Science.gov (United States)

2010-10-01

... OF TRANSPORTATION FEDERAL MOTOR VEHICLE THEFT PREVENTION STANDARD PHASE-IN AND SMALL-VOLUME LINE REPORTING REQUIREMENTS § 545.1 Scope. This part establishes requirements for manufacturers of motor vehicles..., concerning the number of vehicles that meet the requirements of 49 CFR part 541, and the number of vehicles...

29 CFR 1607.2 - Scope.

Science.gov (United States)

2010-07-01

... PROCEDURES (1978) General Principles § 1607.2 Scope. A. Application of guidelines. These guidelines will be... the Department of Labor, and the contract compliance agencies until the transfer of authority... responsibilities under Federal law; by the Office of Revenue Sharing of the Department of the Treasury under the...

32 CFR 516.38 - Scope.

Science.gov (United States)

2010-07-01

... 32 National Defense 3 2010-07-01 2010-07-01 true Scope. 516.38 Section 516.38 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS... involving missions and functions of DA, its major and subordinate commands, all installations presently or...

15 CFR 990.11 - Scope.

Science.gov (United States)

2010-01-01

... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OIL POLLUTION ACT REGULATIONS NATURAL RESOURCE DAMAGE ASSESSMENTS Introduction § 990.11 Scope. The Oil Pollution Act of 1990 (OPA), 33 U.S.C. 2701 et seq., provides for the designation of federal, state, and, if designated by the Governor of the state, local...

Nature and scope of public administration

Directory of Open Access Journals (Sweden)

Uchem, R.O.

2013-03-01

Full Text Available The success and survival of any organizations be they government or not is contingent upon group efforts and cooperation to achieve set goals. This paper discusses the nature and scope of public administration to say that in modern day societies, any administration in the public interest transcends beyond government circles and finds expression in other spheres of human endeavors including the church, mosques, postal services as well as international relations and diplomacy, respectively. The paper discusses the concepts of administration and public administration thereby creating a distinction between the two concepts. Furthermore, the understanding of the scope of administration through the various schools of thought have also been captured, the essence of which is to generate a clearer understanding of the discourse under review. The paper ends with conclusions.

Isotope Production Facility Conceptual Thermal-Hydraulic Design Review and Scoping Calculations

International Nuclear Information System (INIS)

Pasamehmetoglu, K.O.; Shelton, J.D.

1998-01-01

The thermal-hydraulic design of the target for the Isotope Production Facility (IPF) is reviewed. In support of the technical review, scoping calculations are performed. The results of the review and scoping calculations are presented in this report

41 CFR 101-27.500 - Scope and applicability of subpart.

Science.gov (United States)

2010-07-01

... MANAGEMENT 27.5-Return of GSA Stock Items § 101-27.500 Scope and applicability of subpart. This subpart sets... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Scope and applicability of subpart. 101-27.500 Section 101-27.500 Public Contracts and Property Management Federal Property...

12 CFR 717.22 - Scope and duration of opt-out.

Science.gov (United States)

2010-01-01

... CREDIT REPORTING Affiliate Marketing § 717.22 Scope and duration of opt-out. (a) Scope of opt-out. (1) In... as described in the notice to make solicitations to the consumer. (2) Continuing relationship. (i) In general. If the consumer establishes a continuing relationship with you or your affiliate, an opt-out...

12 CFR 571.22 - Scope and duration of opt-out.

Science.gov (United States)

2010-01-01

... REPORTING Affiliate Marketing § 571.22 Scope and duration of opt-out. (a) Scope of opt-out—(1) In general... described in the notice to make solicitations to the consumer. (2) Continuing relationship—(i) In general. If the consumer establishes a continuing relationship with you or your affiliate, an opt-out notice...

16 CFR 680.22 - Scope and duration of opt-out.

Science.gov (United States)

2010-01-01

... MARKETING § 680.22 Scope and duration of opt-out. (a) Scope of opt-out—(1) In general. Except as otherwise... make solicitations to the consumer. (2) Continuing relationship—(i) In general. If the consumer establishes a continuing relationship with you or your affiliate, an opt-out notice may apply to eligibility...

7 CFR 3016.1 - Purpose and scope of this part.

Science.gov (United States)

2010-01-01

... AND LOCAL GOVERNMENTS General § 3016.1 Purpose and scope of this part. This part establishes uniform... 7 Agriculture 15 2010-01-01 2010-01-01 false Purpose and scope of this part. 3016.1 Section 3016.1 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER...

Rural residents' perspectives on the rural 'good death': a scoping review.

Science.gov (United States)

Rainsford, Suzanne; MacLeod, Roderick D; Glasgow, Nicholas J; Wilson, Donna M; Phillips, Christine B; Wiles, Robert B

2018-05-01

The 'good death' is one objective of palliative care, with many 'good death' viewpoints and research findings reflecting the urban voice. Rural areas are distinct and need special consideration. This scoping review identified and charted current research knowledge on the 'good' rural death through the perspectives of rural residents, including rural patients with a life-limiting illness, to identify evidence and gaps in the literature for future studies. A comprehensive literature search of English language articles (no date filter applied) was conducted in 2016 (2 January to 14 February) using five library databases. Reference lists of included articles, recent issues of eight relevant journals and three grey literature databases were also hand-searched. Twenty articles (for 17 studies and one systematic review) were identified after a two-phase screening process by two reviewers, using pre-determined inclusion criteria. Data from each study were extracted and charted, analysed using a thematic analysis of the included articles' content, and with a quantitative analysis of the scoping review. These papers revealed data collected from rural patients with a life-limiting illness and family caregivers, rural healthcare providers, the wider rural community, rural community leaders and rural health administrators and policy makers. Rural locations were heterogeneous. Residents from developed and developing countries believe a 'good death' is one that is peaceful, free of pain and without suffering; however, this is subjective and priorities are based on personal, cultural, social and religious perspectives. Currently, there is insufficient data to generalise rural residents' perspectives and what it means for them to die well. Given the extreme importance of a 'good death', there is a need for further studies to elicit rural patient and family caregiver perspectives. © 2016 John Wiley & Sons Ltd.

14 CFR 1216.200 - Scope.

Science.gov (United States)

2010-01-01

... Management; and, (h) Establish internal management controls to monitor NASA actions to assure compliance with... Wetlands Management § 1216.200 Scope. This subpart 1216.2 prescribes procedures to: (a) Avoid long- and... practicable alternative; (c) Reduce the risk of flood loss; (d) Minimize the impact of floods on human health...

12 CFR 19.220 - Scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Scope. 19.220 Section 19.220 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY RULES OF PRACTICE AND PROCEDURE Procedures for... the OCC pursuant to section 38 of the Federal Deposit Insurance Act and this part. ...

12 CFR 19.210 - Scope.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Scope. 19.210 Section 19.210 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY RULES OF PRACTICE AND PROCEDURE Equal Access to... adjudicatory proceedings under this part are set forth at 31 CFR part 6. ...

49 CFR 543.1 - Scope.

Science.gov (United States)

2010-10-01

... OF TRANSPORTATION EXEMPTION FROM VEHICLE THEFT PREVENTION STANDARD § 543.1 Scope. This part establishes procedures under section 605 of the Motor Vehicle Information and Cost Savings Act (15 U.S.C. 2025) for filing and processing petitions to exempt lines of passenger motor vehicles from part 541 of this...

21 CFR 864.1 - Scope.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Scope. 864.1 Section 864.1 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND... hematology and pathology devices intended for human use that are in commercial distribution. (b) The...

19 CFR 113.0 - Scope.

Science.gov (United States)

2010-04-01

... general authority and powers of the Commissioner of Customs in requiring bonds, bond approval and... 19 Customs Duties 1 2010-04-01 2010-04-01 false Scope. 113.0 Section 113.0 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS BONDS...

Commercial Art: Scope and Sequence.

Science.gov (United States)

Nashville - Davidson County Metropolitan Public Schools, TN.

This scope and sequence guide, developed for a commercial art vocational education program, represents an initial step in the development of a systemwide articulated curriculum sequence for all vocational programs within the Metropolitan Nashville Public School System. It was developed as a result of needs expressed by teachers, parents, and the…

31 CFR 203.1 - Scope.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Scope. 203.1 Section 203.1 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE PAYMENT OF FEDERAL TAXES AND THE TREASURY TAX AND LOAN PROGRAM...

10 CFR 2.1400 - Purpose and scope of subpart N.

Science.gov (United States)

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Purpose and scope of subpart N. 2.1400 Section 2.1400... ORDERS Expedited Proceedings with Oral Hearings § 2.1400 Purpose and scope of subpart N. The purpose of... parties otherwise agree and request the application of subpart N procedures, and proceedings for the...

The scope of business ethics | Rossouw | South African Journal of ...

African Journals Online (AJOL)

Due to its multi-disciplinary nature, there are a variety of conceptions about the scope of Business Ethics as an academic field. Confusion about the scope of business ethics can impact detrimentally upon the further development of this field of study. The purpose of this article is to distinguish between various notions of the ...

12 CFR 41.22 - Scope and duration of opt-out.

Science.gov (United States)

2010-01-01

... Affiliate Marketing § 41.22 Scope and duration of opt-out. (a) Scope of opt-out. (1) In general. Except as... the notice to make solicitations to the consumer. (2) Continuing relationship. (i) In general. If the consumer establishes a continuing relationship with a bank or its affiliate, an opt-out notice may apply to...

A technological contingency perspective on the dept and scope of international outsourcing

OpenAIRE

Mol, M.J.; PAUWELS, Pieter; MATTHYSSENS, Paul

2006-01-01

In this study we present and test a technological contingency perspective on two dimensions of international outsourcing: depth and scope. The depth of international outsourcing refers to the ratio of foreign to total outsourcing. The scope of international outsourcing refers to the ratio of foreign to total outsourcing. The scope of international outsourcing captures the degree of psychic dispersion between the country of operations and the countries a firm is outsourcing to. Using multiple...

29 CFR 780.150 - Scope and limits of “preparation for market.”

Science.gov (United States)

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Scope and limits of âpreparation for market.â 780.150... STANDARDS ACT General Scope of Agriculture Preparation for Market § 780.150 Scope and limits of “preparation for market.” “Preparation for market” is also named as one of the practices which may be included in...

Economies of scope in Danish primary care practices

DEFF Research Database (Denmark)

Kristensen, Troels; Rose Olsen, Kim

2011-01-01

between GP services and overall economies of scope. Data: Cross-section data for a sample of 331 primary care practices with 1-8 GPs from the year 2006. This is a unique combined dataset consisting of survey and register data. Results: We find a trend towards cost complementarities between the production......Aim: We analyze total operating costs and activities in Danish General Practice units to assess whether there are unexploited economies of scope in the production of primary care services. Methods: We apply stochastic frontier analysis to derive cost functions and associated cost complementarities...

Cost Analysis for Real-time Java Scoped-memory Areas

Directory of Open Access Journals (Sweden)

Delvin Defoe

2007-08-01

Full Text Available Java has recently joined C and C++ as a development platform for real-time and embedded applications. Java's garbage collection, while generally a useful feature, can be problematic for these applications: garbage collection occurs at unpredictable times and its latency is typically unbounded. This can compromise necessary real-time guarantees. To overcome these limitations, the Real-Time for Java Expert Group (RTJEG proposed the Real-Time Specification for Java (RTSJ, which introduced new memory models and new threads to utilize those models. One such memory model uses scoped-memory areas, which work best in the context of a NoHeapRealtimeThread (NHRT. Although much work has been done with scoped-memory areas and NHRTs, there is no system-independent analysis of their costs. In this article we present an asymptotic analysis for RTSJ scoped-memory areas and NHRTs.

Conclusions and recommendations of the SCOPE-RADSITE workshop on remediation achievements after uranium mining and milling

International Nuclear Information System (INIS)

Vandenhove, H.; Vandecasteele, C.M.; Collard, G.

2002-01-01

The SCOPE-RADSITE Project provides a unique international scientific forum where the radioactive wastes generated in the development of nuclear weapons, including their potential impact on the environment and human populations, are studied and reviewed. At the present SCOPE-RADSITE workshop a team of experts presented the current status of uranium mining and milling operations in the United States, in the former Soviet Union (FSU) and in Central and Eastern Europe. The effect of radiocontaminants resulting from the uranium mining and milling operations to species other than humans and the combined effects of environmental radiation and other agents were discussed. Finally, three cases of remediation projects were presented: remediation at COGEMA sites in France, the WISMUT rehabilitation project in Germany and uranium mine reclamation in Texas and remediation achievements were described. Finally the workshop discussed important issues and recommendations to be considered when approaching remediation of past legacies resulting from uranium mining and milling. (author)

Integrating the GalileoScope into Successful Outreach Programming

Science.gov (United States)

Michaud, Peter D.; Slater, S.; Goldstein, J.; Harvey, J.; Garcia, A.

2010-01-01

Since 2004, the Gemini Observatory’s week-long Journey Through the Universe (JTtU) program has successfully shared the excitement of scientific research with teachers, students and the public on Hawaii’s Big Island. Based on the national JTtU program started in 1999, the Hawai‘i version reaches an average of 7,000 students annually and each year features a different theme shared with a diverse set of learners. In 2010, the theme includes the integration of the GalileoScope-produced as a keystone project for the International Year of Astronomy. In preparation, a pilot teacher workshop (held in October 2009) introduced local island teachers to the GalileoScope and a 128-page educator’s activity resource book coordinated by the University of Wyoming. Response from this initial teacher’s workshop has been strong and evaluations plus follow-up actions by participating teachers illustrate that the integration of the GalileoScope has been successful based upon this diverse sample. Integrating GalileoScopes into Chilean schools in 2010 is also underway at Gemini South. This program will solicit informal proposals from educators who wish to use the telescopes in classrooms and a Spanish version of the teacher resource book is planned. The authors conclude that integration of the GalileoScope into an existing outreach program is an effective way to keep content fresh, relevant and engaging for both educators and students. This initiative is funded by Gemini Observatory outreach program. The Gemini Observatory is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (US), the Science and Technology Facilities Council (UK), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), Ministério da Ciência e Tecnologia (Brazil), and Ministerio de Ciencia, Tecnología e Innovación Productiva

78 FR 12702 - Control of Communicable Diseases: Interstate; Scope and Definitions

Science.gov (United States)

2013-02-25

... Control of Communicable Diseases: Interstate; Scope and Definitions AGENCY: Centers for Disease Control... rulemaking; withdrawal. SUMMARY: The Centers for Disease Control and Prevention (CDC) within the Department... Rulemaking (NPRM) that solicited public comment on updates to the Scope and Definitions for its regulations...

20 CFR 361.2 - Scope.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Scope. 361.2 Section 361.2 Employees' Benefits RAILROAD RETIREMENT BOARD INTERNAL ADMINISTRATION, POLICY AND PROCEDURES RECOVERY OF DEBTS OWED TO... seq.), or the tariff laws of the United States; or to any case where collection of a debt by salary...

47 CFR 1.1303 - Scope.

Science.gov (United States)

2010-10-01

... Environmental Policy Act of 1969 § 1.1303 Scope. The provisions of this subpart shall apply to all Commission actions that may or will have a significant impact on the quality of the human environment. To the extent that other provisions of the Commission's rules and regulations are inconsistent with the subpart, the...

10 CFR 707.2 - Scope.

Science.gov (United States)

2010-01-01

...) High risk of danger to life, the environment, public health and safety, or national security; or (iii... authority of the Atomic Energy Act of 1954, as amended: (1) Management and operating contracts; and (2... WORKPLACE SUBSTANCE ABUSE PROGRAMS AT DOE SITES General Provisions § 707.2 Scope. (a) This part applies to...

32 CFR 855.4 - Scope.

Science.gov (United States)

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Scope. 855.4 Section 855.4 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE AIRCRAFT CIVIL AIRCRAFT USE OF UNITED STATES... requirements take precedence over authorized civil aircraft use. This part carries the force of US law, and...

21 CFR 340.1 - Scope.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Scope. 340.1 Section 340.1 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE STIMULANT... stimulant drug product in a form suitable for oral administration is generally recognized as safe and...

14 CFR 77.41 - Scope.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Scope. 77.41 Section 77.41 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE OBJECTS... applies to hearings held by the FAA under titles I, III, and X of the Federal Aviation Act of 1958 (49 U.S...

10 CFR 51.29 - Scoping-environmental impact statement and supplement to environmental impact statement.

Science.gov (United States)

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Scoping-environmental impact statement and supplement to environmental impact statement. 51.29 Section 51.29 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED... Environmental Policy Act-Regulations Implementing Section 102(2) Scoping § 51.29 Scoping-environmental impact...

The carbon we're not counting : accounting for Scope 3 carbon emissions

OpenAIRE

Knight, Alan; Jackson, Rachel

2011-01-01

This report highlights that businesses can’t evaluate the nature, extent and value of greenhouse gas emission-associated risks and opportunities until high-quality information is available. And this means an investment in credible and complete carbon accounting. Credible information on Scope 1 and Scope 2 emissions allow a company to better understand what is happening inside its fences. But more significant is the carbon many businesses aren’t counting. Scope 3 emissions look across the full...

Special safeguards study. Scopes of work

International Nuclear Information System (INIS)

1975-06-01

The Special Safeguards Study (SSS) will be conducted by a combination of (1) contacts with other agencies, (2) NRC staff studies and analysis and (3) contracted studies in specific areas. Most of the study effort will be carried out by contractual support activities. These activities will be devoted to providing technical information, primarily qualitative because of the short term of the study, to enable the staff to determine the most cost-effective sets of measures for plutonium recycle and high-enriched uranium fuel cycle safeguards. The scope of work for these activities is given. The scope of work describes tasks that range from confirming the Commission's safeguards objective to defining specific protection systems for the following siting arrangements: dispersed sites, collocated fuel cycle plants, and mixed parks where reactors, reprocessing plants and fuel fabrication plants are collocated. (U.S.)

Reduced attentional scope in cocaine polydrug users.

Directory of Open Access Journals (Sweden)

Lorenza S Colzato

Full Text Available Cocaine is Europe's second preferred recreational drug after cannabis but very little is known about possible cognitive impairments in the upcoming type of recreational cocaine user (monthly consumption. We asked whether recreational use of cocaine impacts early attentional selection processes. Cocaine-free polydrug controls (n = 18 and cocaine polydrug users (n = 18 were matched on sex, age, alcohol consumption, and IQ (using the Raven's progressive matrices, and were tested by using the Global-Local task to measure the scope of attention. Cocaine polydrug users attended significantly more to local aspects of attended events, which fits with the idea that a reduced scope of attention may be associated with the perpetuation of the use of the drug.

47 CFR 51.701 - Scope of transport and termination pricing rules.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false Scope of transport and termination pricing rules. 51.701 Section 51.701 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON... Telecommunications Traffic § 51.701 Scope of transport and termination pricing rules. (a) The provisions of this...

[Identification of the scope of practice for dental nurses with Delphi method].

Science.gov (United States)

Li, Yu-Hong; Lu, Yue-Cen; Huang, Yao; Ruan, Hong; Wu, Zheng-Yi

2016-10-01

To identify the practice scope of dental nurses under the new situations. The draft of scope of practice for dental nurses was based on theoretical analysis, literature review and consultation of advisory panel, and the final scope of practice for dental nurses was established by using the Delphi method. Statistical analysis was implemented using coefficient of variation, Kendall W with SPSS 17.0 software package. Thirty experts were consulted twice by using the Delphi method. The effective rates of two rounds of questionnaire were 100% and 73.3%, respectively. The authority coefficient was 0.837, and the P value of expert coordination coefficients W was less than 0.05. There were totally 116 suggestions from the experts, and 96 were accepted. The scope of practice for dental nurses was finally established, including 4 primary indexes and 25 secondary indexes. The scope of practice for dental nurses under the new situations is established in China through scientific methods. It is favorable for position management of dental nurses and may promote the development of nurse specialists in dental clinic.

46 CFR 164.019-1 - Scope.

Science.gov (United States)

2010-10-01

..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL MATERIALS Personal Flotation Device Components § 164.019-1 Scope. (a) This subpart contains general requirements for standard personal flotation device (PFD) components, procedures for acceptance of...

Tank farm restoration and safe operation, Project W-314, upgrade scope summary report (USSR)

International Nuclear Information System (INIS)

Gilbert, J.L.

1998-01-01

The revision to the Project W-314 Upgrade Scope Summary Report (USSR), incorporates changes to the project scope from customer guidance. Included are incorporation of the recommendations from HNF-2500, agreements regarding interfaces with Project W-211, and assumption of scope previously assigned to Project W-454

From polycrystal to multi-crystal: ''numerical meso-scope'' development for a local analysis in the elasto-viscoplastic field

International Nuclear Information System (INIS)

Heraud, St.

2000-01-01

The knowledge of the local mechanical fields over several adjacent grains is needed for a better understanding of damage initiation and intergranular. failure in metallic polycrystals. This thesis aimed at the derivation of such fields through a 'numerical meso-scope': this simulation tool relies on the finite element analysis of a multi-crystalline pattern embedded in a large matrix whose mechanical behaviour is derived experimentally from classical tests performed on the studied metal. First, we derived macroscopic elastic-viscoplastic constitutive equations from tensile and creep tests on a AIS1316 stainless steel and we inferred from them the general form of similar, but crystallographic equations to be used for the single crystals; the corresponding parameters were determined by fitting the computed overall response of an aggregate made of 1000 grains with the macroscopic experimental one. We then investigated a creep-damaged area of the same steel and we simulated the same grain ensemble in the 'numerical meso-scope' so as to compare the computed normal stress on all grain boundaries with the observed de-bonded boundaries: this showed the most damaged boundaries to sustain the largest normal stress. Another application was concerned with the understanding of the origin of intergranular damage of aged AIS321 stainless steel. A similar approach was adopted with help of the meso-scope: it showed that observations could not be explained by a sole intragranular hardening as it is currently proposed in the literature. Thus the pertinence of the 'numerical meso-scope' concept can now be demonstrated, which opens on a number of new interesting perspectives. (author)

Full-scope nuclear training simulator -brought to the desktop

International Nuclear Information System (INIS)

LaPointe, D.J.; Manz, A.; Hall, G.S.

1997-01-01

RighTSTEP is a suite of simulation software which has been initially designed to facilitate upgrade of Ontario Hydro's full-scope simulators, but is also adaptable to a variety of other roles. it is presently being commissioned at Bruch A Training Simulator and has seen preliminary use in desktop and classroom roles. Because of the flexibility of the system, we anticipate it will see common use in the corporation for full-scope simulation roles. A key reason for developing RighTSTEP (Real Time Simulator Technology Extensible and Portable) was the need to modernize and upgrade the full-scope training simulator while protecting the investment in modelling code. This modelling code represents the end product of 18 years of evolution from the beginning of its development in 1979. Bringing this modelling code to a modern and more useful framework - the combination of simulator host, operating system, and simulator operating system - also could provide many spin-off benefits. The development (and first implementation) of the righTSTEP system was cited for saving the corporation 5.6M$ and was recognized by a corporate New Technology Award last year. The most important spin-off from this project has been the desktop version of the full-scope simulator. The desktop simulator uses essentially the same software as does its full-scope counterpart, and may be used for a variety of new purposes. Classroom and individual simulator training can now be easily accommodated since a desktop simulator is both affordable and relatively ease to use. Further, a wide group of people can be trained using the desktop simulator: by contrast the full-scope simulators were almost exclusively devoted to front-line operating staff. The desktop is finding increasing use in support of engineering applications, resulting from its easy accessibility, breadth of station systems represented, and tools for analysis and viewing. As further plant models are made available on the new simulator platform and

12 CFR 13.1 - Scope.

Science.gov (United States)

2010-01-01

... COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY GOVERNMENT SECURITIES SALES PRACTICES § 13.1 Scope. This part applies to national banks that have filed notice as, or are required to file notice as.... 78o-5) and Department of the Treasury rules under section 15C (17 CFR 400.1(d) and part 401). ...

21 CFR 814.1 - Scope.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Scope. 814.1 Section 814.1 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PREMARKET... paragraph (a), effective Aug. 16, 2010. For the convenience of the user, the revised text is set forth as...

30 CFR 90.1 - Scope.

Science.gov (United States)

2010-07-01

... respirable dust sampling for Part 90 miners. This Part 90 is promulgated pursuant to section 101 of the Act... STANDARDS-COAL MINERS WHO HAVE EVIDENCE OF THE DEVELOPMENT OF PNEUMOCONIOSIS General § 90.1 Scope. This Part 90 establishes the option of miners who are employed at underground coal mines or at surface work...

Scope of nanotechnology in modern textiles

Science.gov (United States)

This review article demonstrates the scope and applications of nanotechnology towards modification and development of advanced textile fibers, yarns and fabrics and their processing techniques. Basically, it summarizes the recent advances made in nanotechnology and its applications to cotton textil...

46 CFR 161.012-1 - Scope.

Science.gov (United States)

2010-10-01

..., DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL ELECTRICAL EQUIPMENT Personal Flotation Device Lights § 161.012-1 Scope. (a) This subpart... approving personal flotation device lights fitted on Coast Guard approved life preservers, bouyant vests...

41 CFR 101-39.200 - Scope.

Science.gov (United States)

2010-07-01

... FEDERAL PROPERTY MANAGEMENT REGULATIONS AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 39-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.2-GSA Interagency Fleet Management System Services § 101-39.200 Scope. This subpart... Administration (GSA) Interagency Fleet Management System (IFMS). Local transportation services for Government...

78 FR 12702 - Control of Communicable Diseases: Foreign; Scope and Definitions

Science.gov (United States)

2013-02-25

... Control of Communicable Diseases: Foreign; Scope and Definitions AGENCY: Centers for Disease Control and...; withdrawal. SUMMARY: The Centers for Disease Control and Prevention (CDC) within the Department of Health and... solicited public comment on updates to the Scope and Definitions for its regulations. DATES: The Notice of...

Scale and Scope Economies in the Global Advertising and Marketing Services Business

OpenAIRE

Alvin J. Silk; Ernst R. Berndt

2003-01-01

We assess size and scope-related economies in the global advertising and marketing services business. A translog cost function is employed wherein a firm's costs vary according to its scale and two dimensions of the scope of its operations. Parameters of the model are estimated via three stage least squares using annual data for 1989-2001 for an unbalanced panel consisting of the eight largest firms in this industry. A firm's total variable costs are affected by its scale, scope (mix of servi...

United Kingdom. Report 2 [Marine Radioecology. Current Research and Future Scope

International Nuclear Information System (INIS)

Martin, J.H.

1967-01-01

Present research programme: 1.1. The biology of the Solway Firth in relation to the movement and accumulation of radioactive materials. 1.2. To determine the maximum capacity of the Solway Firth for the receipt of radioactive effluent. 1.3. The work has included study of the estuarine currents, using drifters; study of the relationship between deposition of radioactivity and soil by means of transects; studies of the nature and variation, with season and position in the estuary, of fish feeding; and studies of the flora and fauna of the estuary (including some minor studies of how they are affected by climatic changes)

Burnout and Scope of Practice in New Family Physicians.

Science.gov (United States)

Weidner, Amanda K H; Phillips, Robert L; Fang, Bo; Peterson, Lars E

2018-05-01

Family physicians report some of the highest levels of burnout, but no published work has considered whether burnout is correlated with the broad scope of care that family physicians may provide. We examined the associations between family physician scope of practice and self-reported burnout. Secondary analysis of the 2016 National Family Medicine Graduate Survey respondents who provided outpatient continuity care (N = 1,617). We used bivariate analyses and logistic regression to compare self-report of burnout and measures of scope of practice including: inpatient medicine, obstetrics, pediatric ambulatory care, number of procedures and/or clinical content areas, and providing care outside the principal practice site. Forty-two percent of respondents reported feeling burned out from their work once a week or more. In bivariate analysis, elements of scope of practice associated with higher burnout rates included providing more procedures/clinical content areas (mean procedures/clinical areas: 7.49 vs 7.02; P = .02) and working in more settings than the principal practice site (1+ additional settings: 57.6% vs 48.4%: P = .001); specifically in the hospital (31.4% vs 24.2%; P = .002) and patient homes (3.3% vs 1.5%; P = .02). In adjusted analysis, practice characteristics significantly associated with lower odds of burnout were practicing inpatient medicine (OR = 0.70; 95% CI, 0.56-0.87; P = .0017) and obstetrics (OR = 0.64; 95% CI, 0.47-0.88; P = .0058). Early career family physicians who provide a broader scope of practice, specifically, inpatient medicine, obstetrics, or home visits, reported significantly lower rates of burnout. Our findings suggest that comprehensiveness is associated with less burnout, which is critical in the context of improving access to good quality, affordable care while maintaining physician wellness. © 2018 Annals of Family Medicine, Inc.

Interpersonal Relationships, Motivation, Engagement, and Achievement: Yields for Theory, Current Issues, and Educational Practice

Science.gov (United States)

Martin, Andrew J.; Dowson, Martin

2009-01-01

In this review, we scope the role of interpersonal relationships in students' academic motivation, engagement, and achievement. We argue that achievement motivation theory, current issues, and educational practice can be conceptualized in relational terms. Influential theorizing, including attribution theory, expectancy-value theory, goal theory,…

Measuring actual scope of nursing practice: a new tool for nurse leaders.

Science.gov (United States)

D'Amour, Danielle; Dubois, Carl-Ardy; Déry, Johanne; Clarke, Sean; Tchouaket, Eric; Blais, Régis; Rivard, Michèle

2012-05-01

: This project describes the development and testing of the actual scope of nursing practice questionnaire. : Underutilization of the skill sets of registered nurses (RNs) is a widespread concern. Cost-effective, safe, and efficient care requires support by management to facilitate the implementation of nursing practice at the full scope. : Literature review, expert consultation, and face validity testing were used in item development. The instrument was tested with 285 nurses in 22 medical units in 11 hospitals in Canada. : The 26-item, 6-dimension questionnaire demonstrated validity and reliability. The responses suggest that nurses practice at less than their optimal scope, with key dimensions of professional practice being implemented infrequently. : This instrument can help nurse leaders increase the effective use of RN time in carrying out the full scope of their professional practice.

An overview of the fire risk scoping study

International Nuclear Information System (INIS)

Nowlen, S.P.; Lambright, J.A.; Nicolette, V.F.; Bohn, M.P.

1989-01-01

The Fire Risk Scoping Study was sponsored by the US Nuclear Regulatory Commission and performed at Sandia National Laboratories. The study was initiated as a result of previous USNRC-sponsored fire research efforts that had identified certain fire risk issues that had not been addressed in previously completed commercial nuclear power plant fire risk analyses. The specific objectives of this study were (1) to review and requantify fire risk scenarios from four fire probabilistic risk assessments in light of updated data bases made available as a result of USNRC-sponsored Fire Protection Research Program and updated computer fire modeling capabilities, (2) to identify potentially significant fire risk issues that have not been previously addressed in a fire risk context and to quantify the potential impact of those identified fire risk issues where possible, and (3) to review current fire regulations and plant implementation practices for relevance to the identified unaddressed fire risk issues. 9 refs., 3 tabs

Occupation-based practices and homelessness: A scoping review.

Science.gov (United States)

Roy, Laurence; Vallée, Catherine; Kirsh, Bonnie H; Marshall, Carrie Anne; Marval, Rebecca; Low, Alissa

2017-04-01

Persons experiencing or at risk of homelessness have occupational needs that are seldom addressed in the Canadian system of care. The lack of documented evidence on occupational therapy practices in this field hinders the development of the profession. This article identifies current and potential practices that aim to enable or support the occupations of persons experiencing or at risk of homelessness. A scoping review was conducted, including evidence from both occupational therapy and non-occupational therapy sources. One hundred and seventy-eight papers were selected in the areas of occupational performance skills training, enrichment of occupational repertoire, employment/education, physical rehabilitation services, child/family services, community building, occupational transition from homeless to housed, literacy, and disaster relief. Occupational therapists can build environments and create opportunities that facilitate occupational engagement of individuals experiencing homelessness. Gaps in knowledge include the evaluation of occupational therapy practices, the Canadian context of family homelessness, and the cultural safety of occupational therapy interventions.

48 CFR 750.7100 - Scope of subpart.

Science.gov (United States)

2010-10-01

... MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy Interests of the United States 750.7100 Scope of subpart. This subpart sets forth the standards and the...

A Self-adaptive Scope Allocation Scheme for Labeling Dynamic XML Documents

NARCIS (Netherlands)

Shen, Y.; Feng, L.; Shen, T.; Wang, B.

This paper proposes a self-adaptive scope allocation scheme for labeling dynamic XML documents. It is general, light-weight and can be built upon existing data retrieval mechanisms. Bayesian inference is used to compute the actual scope allocated for labeling a certain node based on both the prior

21 CFR 17.1 - Scope.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Scope. 17.1 Section 17.1 Food and Drugs FOOD AND... Food, Drug, and Cosmetic Act (the act) authorizing civil money penalties for certain violations of the... trial data bank and section 303(f)(4) of the act authorizing civil money penalties for certain...

SCOPE, Shipping Cask Optimization and Parametric Evaluation

International Nuclear Information System (INIS)

2002-01-01

1 - Description of program or function: Given the neutron and gamma-ray shielding requirements as input, SCOPE may be used as a conceptual design tool for the evaluation of various casks designed to carry square fuel assemblies, circular canisters of nuclear waste material, or circular canisters containing 'intact' spent-fuel assemblies. It may be used to evaluate a specific design or to search for the maximum number of full assemblies (or canisters) that might be shipped in a given type of cask. In the 'search' mode, SCOPE will use built-in packing arrangements and the tabulated shielding requirements input by the user to 'design' a cask carrying one fuel assembly (or canister); it will then continue to increment the number of assemblies (or canisters) until one or more of the design limits can no longer be met. In each case (N = 1,2,3...), SCOPE will calculate the steady-state temperature distribution throughout the cask and perform a complete 1-D space/time transient thermal analysis following a postulated half-hour fire; then it will edit the characteristic dimensions of the cask (including fins, if required), the total weight of the loaded case, the steady-state temperature distribution at selected points, and the maximum transient temperature in key components. With SCOPE, the effects of various design changes may be evaluated quickly and inexpensively. 2 - Method of solution: SCOPE assumes that the user has already made an independent determination of the neutron and gamma-ray shielding requirements for the particular type of cask(s) under study. The amount of shielding required obviously depends on the type of spent fuel or nuclear waste material, its burnup and/or exposure, the decay time, and the number of assemblies or canisters in the cask. Source terms (and spectra) for spent PWR and BWR fuel assemblies are provided at each of 17 decay times, along with recommended neutron and gamma-ray shield thicknesses for Pb, Fe, and U-metal casks containing a

Current and Future Research Directions in Requirements Engineering

Science.gov (United States)

Cheng, Betty H. C.; Atlee, Joanne M.

In this paper, we review current requirements engineering (RE) research and identify future research directions suggested by emerging software needs. First, we overview the state of the art in RE research. The research is considered with respect to technologies developed to address specific requirements tasks, such as elicitation, modeling, and analysis. Such a review enables us to identify mature areas of research, as well as areas that warrant further investigation. Next, we review several strategies for performing and extending RE research results, to help delineate the scope of future research directions. Finally, we highlight what we consider to be the “hot” current and future research topics, which aim to address RE needs for emerging systems of the future.

48 CFR 3004.470-1 - Scope.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Scope. 3004.470-1 Section 3004.470-1 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY... unclassified facilities, Information Technology (IT) resources, and sensitive information during the...

The TS 600: automatic control system for eddy currents

International Nuclear Information System (INIS)

Poulet, J.P.

1986-10-01

In the scope of fabrication and in service inspection of the PWR steam generator tubing bendle, FRAMATOME developed an automatic Eddy Current testing system: TS600. Based on a mini-computer, TS600 allows to digitize, to store and to process data in various ways, so it is possible to perform several kinds of inspection: conventional inservice inspection, roll area profilometry...... TS600 can also be used to develop new methods of examination [fr

14 CFR 1204.400 - Scope of subpart.

Science.gov (United States)

2010-01-01

... Business Policy § 1204.400 Scope of subpart. This subpart establishes NASA's small business policy and outlines the delegation of authority in implementing this policy as required by Federal law. ...

48 CFR 18.000 - Scope of part.

Science.gov (United States)

2010-10-01

... AND CONTRACT TYPES EMERGENCY ACQUISITIONS 18.000 Scope of part. (a) This part identifies acquisition... and limitations set forth in FAR Part 3, Improper Business Practices and Personal Conflicts of...

Shell Inspection History and Current CMM Inspection Efforts

Energy Technology Data Exchange (ETDEWEB)

Montano, Joshua Daniel [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2017-01-26

The following report provides a review of past and current CMM Shell Inspection efforts. Calibration of the Sheffield rotary contour gauge has expired and the primary inspector, Matthew Naranjo, has retired. Efforts within the Inspection team are transitioning from maintaining and training new inspectors on Sheffield to off-the-shelf CMM technology. Although inspection of a shell has many requirements, the scope of the data presented in this report focuses on the inner contour, outer contour, radial wall thickness and mass comparisons.

Prioritizing health: a systematic approach to scoping determinants in health impact assessment

Directory of Open Access Journals (Sweden)

Lindsay McCallum

2016-08-01

Full Text Available The determinants of health are those factors that have the potential to affect health, either positively or negatively, and include a range of personal, social, economic, and environmental factors. In the practice of Health Impact Assessment (HIA, the stage at which the determinants of health are considered for inclusion is during the scoping step. The scoping step is intended to identify how the HIA will be carried out and to set the boundaries (e.g., temporal and geographical for the assessment. There are several factors that can help to inform the scoping process, many of which are considered in existing HIA tools and guidance; however, a systematic method of prioritizing determinants was found to be lacking. In order to analyze existing HIA scoping tools that are available, a systematic literature review was conducted including both primary and grey literature. A total of 10 HIA Scoping tools met the inclusion/exclusion criteria and were carried forward for comparative analysis. The analysis focused on minimum elements and practice standards of HIA scoping that have been established in the field. The analysis determined that existing approaches lack a clear, systematic method of prioritization of health determinants for inclusion in HIA. This finding led to the development of a Systematic HIA Scoping tool that addressed this gap. The decision matrix tool uses factors such as impact, public concern and data availability to prioritize health determinants. Additionally, the tool allows for identification of data gaps and provides a transparent method for budget allocation and assessment planning. In order to increase efficiency and improve utility, the tool was programmed into Microsoft Excel. Future work in the area of HIA methodology development is vital to the ongoing success of the practice and utilization of HIA as a reliable decision-making tool.

48 CFR 10.000 - Scope of part.

Science.gov (United States)

2010-10-01

... MARKET RESEARCH 10.000 Scope of part. This part prescribes policies and procedures for conducting market research to arrive at the most suitable approach to acquiring, distributing, and supporting supplies and...

75 FR 14138 - Notice of Scope Rulings

Science.gov (United States)

2010-03-24

... the People's Republic of China Requestor: Tubos California; steel pipes used in water delivery systems, water and sewer purification systems and/or water filtration systems are within the scope of the...

5 CFR 841.701 - Purpose and scope.

Science.gov (United States)

2010-01-01

... (CONTINUED) FEDERAL EMPLOYEES RETIREMENT SYSTEM-GENERAL ADMINISTRATION Cost-of-Living Adjustments § 841.701 Purpose and scope. (a) The purpose of this subpart is to regulate computation of cost-of-living...

48 CFR 4.500 - Scope of subpart.

Science.gov (United States)

2010-10-01

... MATTERS Electronic Commerce in Contracting 4.500 Scope of subpart. This subpart provides policy and procedures for the establishment and use of electronic commerce in Federal acquisition as required by Section...

45 CFR 63.16 - Scope of subpart.

Science.gov (United States)

2010-10-01

... OFFICE OF THE ASSISTANT SECRETARY FOR PLANNING AND EVALUATION Financial Provisions § 63.16 Scope of subpart. This subpart sets forth supplemental financial provisions which apply to all grants awarded by...

Method of measuring the current density distribution and emittance of pulsed electron beams

International Nuclear Information System (INIS)

Schilling, H.B.

1979-07-01

This method of current density measurement employs an array of many Faraday cups, each cup being terminated by an integrating capacitor. The voltages of the capacitors are subsequently displayed on a scope, thus giving the complete current density distribution with one shot. In the case of emittance measurements, a moveable small-diameter aperture is inserted at some distance in front of the cup array. Typical results with a two-cathode, two-energy electron source are presented. (orig.)

A Scoping Review of Qualitative Studies about Children Experiencing Parental Separation

Science.gov (United States)

Birnbaum, Rachel; Saini, Michael

2013-01-01

This article explores a scoping review of qualitative studies about children's experiences and feelings during times of parental separation. The purpose of the review was to explore children's feelings and attitudes about their parents' separation and how their voices are heard during times of parental separation. The scoping review examined 44…

48 CFR 7.400 - Scope of subpart.

Science.gov (United States)

2010-10-01

... ACQUISITION PLANNING Equipment Lease or Purchase 7.400 Scope of subpart. This subpart provides guidance pertaining to the decision to acquire equipment by lease or purchase. It applies to both the initial...

Just telling and selling: current limitations in the use of digital media in public health: a scoping review.

Science.gov (United States)

Clar, C; Dyakova, M; Curtis, K; Dawson, C; Donnelly, P; Knifton, L; Clarke, A

2014-12-01

To undertake a scoping review and to map research in the area of digital media use in public health. Scoping review. PubMed, PsycINFO, Google and major textbooks of public health communication and health psychology were searched for primary studies or systematic reviews examining the use of digital media in a health context. Searches focussed on studies published between the start of 2000 and the end of June 2013. Abstracts of reviews of public health interventions were examined with respect to target groups, health topic, intervention characteristics, media used, study design, issues of quality and ethics, and outcomes. To map this area of work fully, this information was supplemented by adding information from primary studies. Areas were identified where systematic review evidence was scarce or non-existent by comparing the final map with information from the reviews analysed. 221 systematic reviews related to digital media use in a public health context were included. Most reviews included studies with an experimental design and general 'at risk' target populations. Specific settings were not specified in the majority of reviews. A large variety of health topics were covered. About a quarter of reviews did not specify a health topic but were concerned with broader issues of health promotion, disease prevention, or health education. Over half of the reviews focussed on eHealth and telemedicine, and another third were concerned with mass media - social marketing. Reviews most frequently reported behaviour-related outcomes or conducted some form of content analysis or analysis of the use of particular media. Research gaps were identified relating to community-based research, participation and empowerment, active media use (especially with respect to visual media und use of specific visual methodologies), and the use of salutogenic or assets-based approaches. The available research relating to digital media use in public health is dominated by studies relating to e

Current concepts of severe asthma

Science.gov (United States)

Raundhal, Mahesh; Oriss, Timothy B.; Ray, Prabir; Wenzel, Sally E.

2016-01-01

The term asthma encompasses a disease spectrum with mild to very severe disease phenotypes whose traditional common characteristic is reversible airflow limitation. Unlike milder disease, severe asthma is poorly controlled by the current standard of care. Ongoing studies using advanced molecular and immunological tools along with improved clinical classification show that severe asthma does not identify a specific patient phenotype, but rather includes patients with constant medical needs, whose pathobiologic and clinical characteristics vary widely. Accordingly, in recent clinical trials, therapies guided by specific patient characteristics have had better outcomes than previous therapies directed to any subject with a diagnosis of severe asthma. However, there are still significant gaps in our understanding of the full scope of this disease that hinder the development of effective treatments for all severe asthmatics. In this Review, we discuss our current state of knowledge regarding severe asthma, highlighting different molecular and immunological pathways that can be targeted for future therapeutic development. PMID:27367183

Full scope simulator commissioning and training experience at Cernavoda NPP

International Nuclear Information System (INIS)

Balan, M.

2000-01-01

The paper presents the experience gained during commissioning and the initial use of the CANDU training full-scope simulator for operation personnel at Cernavoda NPP. The full-scope simulator as an integral part of the training programs that take place in Cernavoda Nuclear Training Department (CNTD), is mainly used for the development of operational skills, knowledge and attitudes required to operate the plant in a safe and efficient manner. (author)

21 CFR 1.277 - What is the scope of this subpart?

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false What is the scope of this subpart? 1.277 Section 1.277 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL GENERAL ENFORCEMENT REGULATIONS Prior Notice of Imported Food General Provisions § 1.277 What is the scope...

Scope Management of Non-Functional Requirements

NARCIS (Netherlands)

Kassab, M.; Daneva, Maia; Ormandjieva, O.; Mueller, P.; Lyggesmeyer, P.; Maehle, E.

2007-01-01

In order to meet commitments in software projects, a realistic assessment must be made of project scope. Such an assessment relies on the availability of knowledge on the user-defined project requirements and their effort estimates and priorities, as well as their risk. This knowledge enables

Scope Complexity Options Risks Excursions (SCORE) Version 3.0 Mathematical Description.

Energy Technology Data Exchange (ETDEWEB)

Gearhart, Jared Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Samberson, Jonell Nicole [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Shettigar, Subhasini [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jungels, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Welch, Kimberly M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Dean A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2017-03-01

The purpose of the Scope, Complexity, Options, Risks, Excursions (SCORE) model is to estimate the relative complexity of design variants of future warhead options. The results of this model allow those considering these options to understand the complexity tradeoffs between proposed warhead options. The core idea of SCORE is to divide a warhead option into a well- defined set of scope elements and then estimate the complexity of each scope element against a well understood reference system. The uncertainty associated with estimates can also be captured. A weighted summation of the relative complexity of each scope element is used to determine the total complexity of the proposed warhead option or portions of the warhead option (i.e., a National Work Breakdown Structure code). The SCORE analysis process is a growing multi-organizational Nuclear Security Enterprise (NSE) effort, under the management of the NA- 12 led Enterprise Modeling and Analysis Consortium (EMAC), that has provided the data elicitation, integration and computation needed to support the out-year Life Extension Program (LEP) cost estimates included in the Stockpile Stewardship Management Plan (SSMP).

Scoping and public participation in the environmental impact assessment: Finnish experiences

International Nuclear Information System (INIS)

Leskinen, A.

2002-01-01

Environmental Impact Assessment (EIA) is a process that produces information for decision making. Therefore it can be described as planning. It is also a systematic way to compare alternative options. One major lesson learned during the early years of EIA was that everything cannot and should not be assessed. The first reports of the assessments in the US were massive documents that were of very limited use in decision making. Therefore the scoping-phase was adopted. The aim of scoping is to focus on important issues at the beginning of the EIA-process. I try to shed some light to the importance of the scoping or programming phase of the process. (author)

A technological contingency perspective on the depth and scope of international outsourcing

NARCIS (Netherlands)

Mol, M.J.; Pauwels, Pieter; Matthyssens, P.; Quintens, L.

2004-01-01

In this study, we present and test a technological contingency perspective on two dimensions of international outsourcing: depth and scope. The depth of international outsourcing refers to the ratio of foreign to total outsourcing. The scope of international outsourcing captures the degree of

Phenotypic Screening Identifies Synergistically Acting Natural Product Enhancing the Performance of Biomaterial Based Wound Healing

Directory of Open Access Journals (Sweden)

Srinivasan Sivasubramanian

2017-07-01

Full Text Available The potential of multifunctional wound heal biomaterial relies on the optimal content of therapeutic constituents as well as the desirable physical, chemical, and biological properties to accelerate the healing process. Formulating biomaterials such as amnion or collagen based scaffolds with natural products offer an affordable strategy to develop dressing material with high efficiency in healing wounds. Using image based phenotyping and quantification, we screened natural product derived bioactive compounds for modulators of types I and III collagen production from human foreskin derived fibroblast cells. The identified hit was then formulated with amnion to develop a biomaterial, and its biophysical properties, in vitro and in vivo effects were characterized. In addition, we performed functional profiling analyses by PCR array to understand the effect of individual components of these materials on various genes such as inflammatory mediators including chemokines and cytokines, growth factors, fibroblast stimulating markers for collagen secretion, matrix metalloproteinases, etc., associated with wound healing. FACS based cell cycle analyses were carried out to evaluate the potential of biomaterials for induction of proliferation of fibroblasts. Western blot analyses was done to examine the effect of biomaterial on collagen synthesis by cells and compared to cells grown in the presence of growth factors. This work demonstrated an uncomplicated way of identifying components that synergistically promote healing. Besides, we demonstrated that modulating local wound environment using biomaterials with bioactive compounds could enhance healing. This study finds that the developed biomaterials offer immense scope for healing wounds by means of their skin regenerative features such as anti-inflammatory, fibroblast stimulation for collagen secretion as well as inhibition of enzymes and markers impeding the healing, hydrodynamic properties complemented

Implementation experiences of NASTRAN on CDC CYBER 74 SCOPE 3.4 operating system

Science.gov (United States)

Go, J. C.; Hill, R. G.

1973-01-01

The implementation of the NASTRAN system on the CDC CYBER 74 SCOPE 3.4 Operating System is described. The flexibility of the NASTRAN system made it possible to accomplish the change with no major problems. Various sizes of benchmark and test problems, ranging from two hours to less than one minute CP time were run on the CDC CYBER SCOPE 3.3, Univac EXEC-8, and CDC CYBER SCOPE 3.4. The NASTRAN installation deck is provided.

Latin American forensic pathology: scope and needs

Directory of Open Access Journals (Sweden)

Gabriel M. Fonseca

2012-10-01

Full Text Available Pathology pertains to the study of a disease; from ancient times it has sought to explain the cause of death through postmortem examination. The advancement of science and technology has led to a greater definition of roles and has favored its development through different subspecialties among which we stands out forensic pathology. This discipline has its own characteristics, scope, case series, procedures and terminology. Likewise, although forensic pathology does not differ substantially from clinical pathology, significant differences can be found between the Anglo American approach and the Latin American approach. Beyond semantics of these alleged differences, the article reviews the concepts involved and discusses the scope and requirements needed to qualify experts, in the understanding that globalizing criteria should establish new paradigms and define the specific roles of the specialty.

21 CFR 516.31 - Scope of MUMS-drug exclusive marketing rights.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Scope of MUMS-drug exclusive marketing rights. 516... SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS NEW ANIMAL DRUGS FOR MINOR USE AND MINOR SPECIES Designation of a Minor Use or Minor Species New Animal Drug § 516.31 Scope of MUMS-drug exclusive...

Individual, interpersonal, and organisational factors of healthcare conflict: A scoping review.

Science.gov (United States)

Kim, Sara; Bochatay, Naike; Relyea-Chew, Annemarie; Buttrick, Elizabeth; Amdahl, Chris; Kim, Laura; Frans, Elise; Mossanen, Matthew; Khandekar, Azhar; Fehr, Ryan; Lee, Young-Mee

2017-05-01

Unresolved conflicts among healthcare professionals can lead to difficult patient care consequences. This scoping review examines the current healthcare literature that reported sources and consequences of conflict associated with individual, interpersonal, and organisational factors. We identified 99 articles published between 2001 and 2015 from PubMed, Cumulative Index to Nursing and Allied Health Literature, and Excerpta Medical Database. Most reviewed studies relied on healthcare professionals' perceptions and beliefs associated with conflict sources and consequences, with few studies reporting behavioural or organisational change outcomes. Individual conflict sources included personal traits, such as self-focus, self-esteem, or worldview, as well as individuals' conflict management styles. These conflicts posed threats to one's physical, mental, and emotional health and to one's ability to perform at work. Interpersonal dynamics were hampered by colleagues' uncivil behaviours, such as low degree of support, to more destructive behaviours including bullying or humiliation. Perceptions of disrespectful working environment and weakened team collaboration were the main interpersonal conflict consequences. Organisational conflict sources included ambiguity in professional roles, scope of practice, reporting structure, or workflows, negatively affecting healthcare professionals' job satisfactions and intent to stay. Future inquiries into healthcare conflict research may target the following: shifting from research involving single professions to multiple professions; dissemination of studies via journals that promote interprofessional research; inquiries into the roles of unconscious or implicit bias, or psychological capital (i.e., resilience) in healthcare conflict; and diversification of data sources to include hospital or clinic data with implications for conflict sources.

Roles of the spreading scope and effectiveness in spreading dynamics on multiplex networks

Science.gov (United States)

Li, Ming; Liu, Run-Ran; Peng, Dan; Jia, Chun-Xiao; Wang, Bing-Hong

2018-02-01

Comparing with single networks, the multiplex networks bring two main effects on the spreading process among individuals. First, the pathogen or information can be transmitted to more individuals through different layers at one time, which enlarges the spreading scope. Second, through different layers, an individual can also transmit the pathogen or information to the same individuals more than once at one time, which makes the spreading more effective. To understand the different roles of the spreading scope and effectiveness, we propose an epidemic model on multiplex networks with link overlapping, where the spreading effectiveness of each interaction as well as the variety of channels (spreading scope) can be controlled by the number of overlapping links. We find that for Poisson degree distribution, increasing the epidemic scope (the first effect) is more efficient than enhancing epidemic probability (the second effect) to facilitate the spreading process. However, for power-law degree distribution, the effects of the two factors on the spreading dynamics become complicated. Enhancing epidemic probability makes pathogen or rumor easier to outbreak in a finite system. But after that increasing epidemic scopes is still more effective for a wide spreading. Theoretical results along with reasonable explanation for these phenomena are all given in this paper, which indicates that the epidemic scope could play an important role in the spreading dynamics.

Scope for solar hydrogen power plants along Indian coasts

Science.gov (United States)

Hajra, Debdyut; Mukhopadhyay, Swarnav

2016-09-01

Energy is at the core of economic growth and development in the present day world. But relentless and unchecked use of harmful energy resources like fossil fuels (coil and oil), nuclear energy has taken a toll on mother nature. The energy coffers are being rapidly depleted and within a few years all of them will become empty, leaving nothing for the future generations to build on. Their constant usage has degraded the air quality and given way to land and water pollution. Scientists and world leaders have initiated a call for action to shift our dependence from currently popular energy sources to cleaner and renewable energy sources. Search for such energy sources have been going on for many years. Solar energy, wind energy, ocean energy, tidal energy, biofuel, etc. have caught the attention of people. Another such important which has become popular is 'Solar Hydrogen'. Many visionary scientists have called hydrogen the energy of the future. It is produced from water by direct or indirect use of sunlight in a sustainable manner. This paper discusses the current energy scenario, the importance of solar-hydrogen as a fuel and most importantly the scope for solar hydrogen power plants along Indian coastline.

29 CFR 780.104 - How modern specialization affects the scope of agriculture.

Science.gov (United States)

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false How modern specialization affects the scope of agriculture... EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT General Scope of Agriculture Introductory § 780.104 How modern specialization...

Focusing the EarthScope for a broader audience: Advancing geoscience education with interactive kiosks

Science.gov (United States)

Smith-Konter, B. R.; Solis, T.

2012-12-01

A primary objective of the EarthScope Education and Outreach program is to transform technical science into teachable products for a technologically thriving generation. One of the most challenging milestones of scientific research, however, is often the translation of a technical result into a clear teachable moment that is accessible to a broader audience. As 4D multimedia now dominate most aspects of our social environment, science "teaching" now also requires intervention of visualization technology and animation to portray research results in an inviting and stimulating manner. Following the Incorporated Research Institutions for Seismology (IRIS)'s lead in developing interactive Earth science kiosk multimedia (bundled in a free product called Active Earth), we have made a major effort to construct and install customized EarthScope-themed touch screen kiosks in local communities. These kiosks are helping to educate a broader audience about EarthScope's unique instrumentation and observations using interactive animations, games, and virtual field trips. We are also developing new kiosk content that reflect career stories showcasing the personal journeys of EarthScope scientists. To truly bring the interactive aspect of our EarthScope kiosk media into the classroom, we have collaborated with local teachers to develop a one-page EarthScope TerraMap activity worksheet that guides students through kiosk content. These activities are shaping a new pathway for how teachers teach and students learn about planet Earth and its fantastic EarthScope - one click (and touch) at a time.

Examining the scope of multibusiness health care firms: implications for strategy and financial performance.

Science.gov (United States)

Noorein Inamdar, S

2007-08-01

Use theory and data to examine the scope of corporate strategies for multibusiness health care firms, also known as organized or integrated health care delivery systems. Data are from the 2000 HIMSS Analytics Annual Survey of integrated health care delivery systems (IHDS), which provides complete information on businesses owned by IHDS. Scope defined as the breadth and type of businesses in which a firm chooses to compete is measured across seven separate business areas: (1) health plans, (2) ambulatory, (3) acute, (4) subacute, (5) home health, (6) other related nonpatient care businesses, and (7) external collaborations. Theories on strategy and organizational configurations along with measures of scope and a novel dataset were used to classify 796 firms into five mutually exclusive groups. The bases for classification were two competitive dimensions of scope: (1) breadth of businesses and (2) mix of existing core businesses versus new noncore businesses. Unit of analysis is the multibusiness health care firm. Sample consists of 796 firms, defined as nonprofit organizations that own two or more direct patient care businesses in two or more separate areas across the health care value chain. Firms were clustered into five mutually exclusive organizational configurations with unique scope characteristics revealing a new taxonomy of corporate strategies. Analysis of the scope variables revealed five strategic types (along with the number of firms and distinguishing features of each strategy) defined as follows: (1) Core Service Provider (340 firms with the smallest scope providing core set of patient care services), (2) Mission Based (52 firms with the next smallest scope offering core set of services to underserved populations), (3) Contractor (266 firms with medium scope and contracting with physician groups), (4) Health Plan Focus (83 firms with large scope and providing health plans), and (5) Entrepreneur (55 firms with the largest scope offering both a core set

45 CFR 170.400 - Basis and scope.

Science.gov (United States)

2010-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH INFORMATION TECHNOLOGY HEALTH INFORMATION TECHNOLOGY STANDARDS, IMPLEMENTATION SPECIFICATIONS, AND CERTIFICATION CRITERIA AND CERTIFICATION PROGRAMS FOR HEALTH INFORMATION TECHNOLOGY Temporary Certification Program for HIT § 170.400 Basis and scope...

48 CFR 239.7100 - Scope of subpart.

Science.gov (United States)

2010-10-01

... OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Security and Privacy for Computer Systems 239.7100 Scope of subpart. This subpart includes information assurance and... protection of privacy of individuals (see FAR Subpart 24.1). ...

45 CFR 73b.1 - Scope.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Scope. 73b.1 Section 73b.1 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION DEBARMENT OR SUSPENSION OF FORMER EMPLOYEES... officer or employee of the Department, including former and retired officers of the commissioned corps of...

Online peer support interventions for chronic conditions: a scoping review protocol.

Science.gov (United States)

Munce, Sarah Elizabeth Patricia; Shepherd, John; Perrier, Laure; Allin, Sonya; Sweet, Shane N; Tomasone, Jennifer R; Nelson, Michelle L A; Guilcher, Sara J T; Hossain, Saima; Jaglal, Susan

2017-09-24

Peer support is receiving increasing attention as both an effective and cost-effective intervention method to support the self-management of chronic health conditions. Given that an increasing proportion of Canadians have internet access and the increasing implementation of web-based interventions, online peer support interventions are a promising option to address the burden of chronic diseases. Thus, the specific research question of this scoping review is the following: What is known from the existing literature about the key characteristics of online peer support interventions for adults with chronic conditions? METHODS AND ANALYSIS: We will use the methodological frameworks used by Arksey and O'Malley as well as Levac and colleagues for the current scoping review. To be eligible for inclusion, studies must report on adults (≥18 years of age) with one of the Public Health Agency of Canada chronic conditions or HIV/AIDS. We will limit our review to peer support interventions delivered through online formats. All study designs will be included. Only studies published from 2012 onwards will be included to ensure relevance to the current healthcare context and feasibility. Furthermore, only English language studies will be included. Studies will be identified by searching a variety of databases. Two reviewers will independently screen the titles and abstracts identified by the literature search for inclusion (ie, level 1 screening), the full text articles (ie, level 2 screening) and then perform data abstraction. Abstracted data will include study characteristics, participant population, key characteristics of the intervention and outcomes collected. This review will identify the key features of online peer support interventions and could assist in the future development of other online peer support programmes so that effective and sustainable programmes can be developed. © Article author(s) (or their employer(s) unless otherwise stated in the text of the

Veterinary education in Africa: current and future perspectives.

Science.gov (United States)

Swan, G E; Kriek, N P J

2009-03-01

Veterinary education commenced in South Africa in 1920 at the Onderstepoort Veterinary Institute in South Africa in association with the Transvaal University College, now the University of Pretoria. Sir Arnold Theiler, Director of Veterinary Research and Education, was the first Dean. Today there are 46 veterinary training institutions in Africa of which 21 are in sub-Saharan Africa. Veterinary services are indispensable to the sustained health and wellbeing of animals and humans, and agricultural economies of countries worldwide. Veterinary education, postgraduate training, and research, and adequate numbers of veterinarians, are essential to satisfy the millennium development goals, the objectives of NEPAD and the African Union, and the agreements regulating international trade. The relevance of the veterinary profession internationally is currently subject to profound scrutiny. Its contributions are assessed against major environmental, demographic, political, disease, technological and economic needs. The scope of veterinary training in future will have to emphasise veterinary public health, food safety, emerging diseases, international trade, bioterrorism, and biomedical research, within the context of a one-health system focusing on the interface between wildlife, domesticated animals, humans, and their environment. Within the context of time available, it would mean reducing the time allocated to training in the field of companion animals. A brief history and scope of veterinary education; current international trends in veterinary education and provisioning; and some perspectives on future veterinary training and initiatives applicable to Africa are provided.

A scoping review of the uses of the care index in children

NARCIS (Netherlands)

Gupta, E; Innes, N; Schuller, A A; Vermaire, J H; Marshman, Z

OBJECTIVE: To conduct a scoping review of literature to describe how the care index (CI) and restorative index (RI) are used in child populations and to determine whether they are fit for purpose. BASIC RESEARCH DESIGN: Scoping review conducted using the Arksey and O'Malley (2005) framework. METHOD:

7 CFR 1773.38 - Scope of engagement.

Science.gov (United States)

2010-01-01

... § 1773.38 Scope of engagement. (a) RUS requires that the audit procedures set forth in §§ 1773.39 through 1773.45 be performed annually by the CPA during the audit of the RUS borrowers' financial statements...

Revising the Complex Economics of Patent Scope

DEFF Research Database (Denmark)

Howells, John

Merges and Nelson claim to have provided an empirically grounded argument that pioneer patents of 'broad' scope are used to block technological development. It is widely understood in both law and economics that they have, as they claim, faulted Kitch's 'prospect theory' of patents, a theory...... that a function of patents is to enable the coordinated development of novel technical ideas. This article is a critical review of Merges and Nelson's historical empirical evidence. I find that, first, 'broad' scope is only implicated in one of the examples cited by Merges and Nelson as supportive evidence...... - the Wright brothers' warped-wing patent; second, that strict development block, defined as the prevention, or retardation of the development of technology understood to be capable of useful development, was not illustrated by any of their examples. Therefore I conclude that their general thesis...

Breast cancer services in Vietnam: a scoping review.

Science.gov (United States)

Jenkins, Chris; Minh, Luu Ngoc; Anh, Tran Tuan; Ngan, Tran Thu; Tuan, Ngo Tri; Giang, Kim Bao; Hoat, Luu Ngoc; Lohfeld, Lynne; Donnelly, Michael; Van Minh, Hoang; Murray, Liam

2018-01-01

Breast cancer incidence has been increasing consistently in Vietnam. Thus far, there have been no analytical reviews of research produced within this area. We sought to analyse the nature andextent of empirical studies about breast cancer in Vietnam, identifying areas for future research and systemsstrengthening. We undertook a scoping study using a five-stage framework to review published and grey literature in English and Vietnamese on breast cancer detection, diagnosis and treatment. We focused specifically on research discussing the health system and service provision. Our results show that breast cancer screening is limited, with no permanent or integrated national screening activities. There is a lack of information on screening processes and on the integration of screening services with other areas of the health system. Treatment is largely centralised, and across all services there is a lack of evaluation and data collection that would be informative for recommendations seeking to improve accessibility and quality of breast cancer services. This paper is the first scoping review of breast cancer services in Vietnam. It outlines areas for future focus for policy makers and researchers with the objective of strengthening service provision to women with breast cancer across the country while also providing a methodological example for how to conduct a collaborative scoping review.

Evolution of cooperation among game players with non-uniform migration scopes

International Nuclear Information System (INIS)

Zhang, Chunyan; Zhang, Jianlei; Xie, Guangming

2014-01-01

In social dilemmas, cooperation among randomly interacting individuals is often hard to achieve. The situation changes if migration takes place, where game structure jointly evolves with the migration from adverse neighborhoods. Here we introduce a framework combining migration with the individual heterogeneity of migration scopes. When faced with a gloomy outlook, some players prefer vacant sites within their adjacent neighborhoods, while others may migrate within the whole network, provided the sites are empty. Thus, we can make a thorough inquiry of the sustainability of cooperation in a spatially distributed population divided by these two groups, and all possible mixtures between them. Our main result is that small-scope migration and suitable population density can gear up high cooperation levels in the midst of dense populations structured by scale-free networks, while large-scope migration and sparsity favor the cooperator clustering among lattice-structured populations. In this sense, the conditions for the emergence of cooperation are prevailingly created by the spatial reciprocity, and migration also has enough potential to help cooperation to prevail in suitable combination of game parameters in dynamics (e.g., population density, the type of interaction structure and also the migration scope)

48 CFR 1819.7301 - Scope of subpart.

Science.gov (United States)

2010-10-01

...&D, thereby increasing competition, productivity and economic growth. Federal agencies participating... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs 1819.7301 Scope of subpart. The Small Business Innovation Research (SBIR...

16 CFR 1031.9 - Purpose and scope.

Science.gov (United States)

2010-01-01

... Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION PARTICIPATION AND COMMISSION EMPLOYEE INVOLVEMENT IN VOLUNTARY STANDARDS ACTIVITIES Employee Involvement § 1031.9 Purpose and scope. (a) This subpart sets forth the Consumer Product Safety Commission's criteria and requirements governing...

19 CFR 201.42 - Purpose and scope.

Science.gov (United States)

2010-04-01

... Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION National Security Information § 201.42 Purpose and scope. The following regulation supplements Executive Order 12356, National Security Information, April 2, 1982, as it applies to the Commission. ...

Adverse Drug Reaction Identification and Extraction in Social Media: A Scoping Review.

Science.gov (United States)

Lardon, Jérémy; Abdellaoui, Redhouane; Bellet, Florelle; Asfari, Hadyl; Souvignet, Julien; Texier, Nathalie; Jaulent, Marie-Christine; Beyens, Marie-Noëlle; Burgun, Anita; Bousquet, Cédric

2015-07-10

The underreporting of adverse drug reactions (ADRs) through traditional reporting channels is a limitation in the efficiency of the current pharmacovigilance system. Patients' experiences with drugs that they report on social media represent a new source of data that may have some value in postmarketing safety surveillance. A scoping review was undertaken to explore the breadth of evidence about the use of social media as a new source of knowledge for pharmacovigilance. Daubt et al's recommendations for scoping reviews were followed. The research questions were as follows: How can social media be used as a data source for postmarketing drug surveillance? What are the available methods for extracting data? What are the different ways to use these data? We queried PubMed, Embase, and Google Scholar to extract relevant articles that were published before June 2014 and with no lower date limit. Two pairs of reviewers independently screened the selected studies and proposed two themes of review: manual ADR identification (theme 1) and automated ADR extraction from social media (theme 2). Descriptive characteristics were collected from the publications to create a database for themes 1 and 2. Of the 1032 citations from PubMed and Embase, 11 were relevant to the research question. An additional 13 citations were added after further research on the Internet and in reference lists. Themes 1 and 2 explored 11 and 13 articles, respectively. Ways of approaching the use of social media as a pharmacovigilance data source were identified. This scoping review noted multiple methods for identifying target data, extracting them, and evaluating the quality of medical information from social media. It also showed some remaining gaps in the field. Studies related to the identification theme usually failed to accurately assess the completeness, quality, and reliability of the data that were analyzed from social media. Regarding extraction, no study proposed a generic approach to easily

Advanced and extended scope practice of radiographers: The Scottish perspective

International Nuclear Information System (INIS)

Henderson, I.; Mathers, S.A.; McConnell, J.; Minnoch, D.

2016-01-01

Purpose: The impact of changing roles, skill mix and a shortage of consultant radiologists on the profession of diagnostic radiography is not clearly understood in Scotland although the anecdotal perspective suggests the situation in many areas does not equate to that of England. Method: A questionnaire survey was administered to ‘lead diagnostic radiographers’ across all Health Boards in Scotland and this was supplemented with telephone interviews. Results: The implementation of skill mix initiatives and particularly advanced/extended scope practice was found to be geographically variable with limited evidence of change in some areas. Lack of effective funding and backfill for training was found to be a major barrier to change, although it was also acknowledged that opposition from some professional groups could be a major factor. Conclusion: Although there is some optimism and evidence of accelerating change, development of the radiographic workforce in Scotland does not in general compare favourably to the findings of Price et al., in 2007. The reasons are multi-factorial including fiscal, professional and geographical elements. - Highlights: • Implementation of extended scope practice is geographically inconsistent. • AfC banding of radiographers in extended scope roles is inconsistent. • Funding and backfill for training is a recognised difficulty for many managers. • Professional opposition, primarily from radiologists is a barrier to implementation. • Extended scope roles make a notable contribution to enhanced outcomes.

Evaluation of Amnion-derived Multipotent Progenitor (AMP) Cells and Amnion-derived Cellular Cytokine Solution (ST266) in Promoting Craniomaxillofacial Regenerative Bone Healing in Critical Size Calvarial Defects

Science.gov (United States)

2017-10-10

well as diseases that can lead to eventual bone loss such as periodontitis (currently being evaluated in human clinical trials). A previous report...28 using ST266 treatment in a rabbit periodontal model revealed that ST266 treatment reduced inflammation and had increased new bone formation [32...The increase in new bone formation may have arisen due to the reduction in chronic inflammation by ST266 treatment, thus allowing the initiation

NEGATIVE AFFECTIVITY, CONSCIENTIOUSNESS AND JOB SCOPE (A CASE OF IT AND TELECOM INDUSTRY

Directory of Open Access Journals (Sweden)

BILAL AFSAR

2010-01-01

Full Text Available Based on a sample of 350 employees in the telecommunication and telecommunication, we obtained empirical evidence suggesting that while individuals high on conscientiousness tended to react more positively to job scope, individuals high on negative affinity tended to react less positively. Job scope was defined as the extent to which a job required the jobholder to be mentally and physically involved to get it done effectively. Typically, a job characterized by a high job scope would be non-repetitive, would need a great deal of independent thought/action and training, would entail the job holder to keep track of his/her progress, and others. The affirmative results obtained in regard of the moderating roles of personality factors in the present study suggested that job design researchers should further explore individuals’ personality differences in response to job scope.

Trends in simulation and the Krsko full scope simulator

International Nuclear Information System (INIS)

Boire, R.; Chatlani, M.

1998-01-01

The nuclear power plant simulation industry is a fast-paced industry yielding continual development as a result of innovations in technology and customer requirements. This paper will discuss the current trends in simulator requirements, the status of simulation technology and the expected future developments, particularly in the context of the NPP Krsko full scope simulator. CAE Electronics has been awarded the contract for the design, construction, integration, testing and commissioning of the NPP Krsko full scope simulator (KFSS) by Nuklearna elektrarna Krsko (NEK). KFSS, as an integral part of the NPP Krsko Modernization plan, has been the subject of an extensive procurement process. KFSS will also take into account the steam generator replacement and plant uprate projects which will be delivered to provide initial training in the modernized plant configuration. As a result, the completed KFSS will meet NEK's goals for reliable training in safe plant operation as well as the licensing requirements of the Slovenian Nuclear Safety Administration. KFSS will be a state-of-the-art facility featuring high fidelity process and control models, proven technology and superior maintainability that will push the envelope of traditional simulator uses. In addition to serving its role as a high quality training vehicle, KFSS will be used for engineering purposes including procedure development and validation, optimization of plant operation and study and validation of plant modifications. KFSS models will be built for the most part with CAE's ROSE TM toolset. ROSE, is a component-based, visual programming environment for the creation, testing, integration and management of simulator models and supporting virtual panels. The NSSS will be simulated using the ANTHEM two-phase drift flux model, while be simulated using the COMET two-group, three-dimensional model. Software design and testing will be supported by an extensive series of quality procedures throughout the software

28 CFR 544.80 - Purpose and scope.

Science.gov (United States)

2010-07-01

... opportunity to improve their knowledge and skills through academic, occupation and leisure-time activities... Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT EDUCATION Education, Training and Leisure-Time Program Standards § 544.80 Purpose and scope. In consideration of...

5 CFR 831.601 - Purpose and scope.

Science.gov (United States)

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Purpose and scope. 831.601 Section 831.601 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT Survivor Annuities Organization and Structure of Regulations on Survivor Annuities...

50 CFR 300.180 - Purpose and scope.

Science.gov (United States)

2010-10-01

... Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS International Trade Documentation and Tracking Programs for Highly Migratory Species § 300.180 Purpose and scope... recommendations of the International Commission for the Conservation of Atlantic Tunas (ICCAT) for the...

28 CFR 32.0 - Scope of part.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Scope of part. 32.0 Section 32.0 Judicial Administration DEPARTMENT OF JUSTICE PUBLIC SAFETY OFFICERS' DEATH, DISABILITY, AND EDUCATIONAL ASSISTANCE...) Educational assistance benefits. [73 FR 76528, Dec. 17, 2008] ...

Scope selection and control

International Nuclear Information System (INIS)

Guglielmi, F.

2011-01-01

OPG is preparing for a 4-unit refurbishment program at Darlington later in this decade. Key efforts underway include the selection of the right refurbishment scope that will allow Darlington to achieve top-decile performance post-refurbishment. For this to be possible, it is imperative that (1) plant/equipment condition be well understood, (2) post-refurbishment performance objectives be clearly defined, and (3) regulatory and other risks be carefully assessed and mitigated. Significant engineering, operations and maintenance support is required to complete this phase of the project cycle.

Status and scope for EOR development in Oman

International Nuclear Information System (INIS)

Al-Adawy, M.S.; Nandyal, M.

1991-01-01

In view of a significant STOIIP (3000 + million m 3 ) of medium/heavy oil (less than 31 degrees API), EOR development in Oman has been and remains a major strategic option in its challenge to increase recovery and to meet long term production requirements. The initial EOR Development Program (1980-89) of which results are highlighted in this paper was based on a series of pilots and tests to gain experience and reduce uncertainties prior to embarking on wider EOR application. The processes tested included Steam and Polymer Flooding in the Marmul field, Steam Soak in five South Oman heavy oil fields and Hot water Injection in the Qarn Alam field. A wide range of reservoir types, oil characteristics and reservoir drive mechanisms have been covered in this test program. The initial program has provided the necessary operating/technical knowledge to enable new projects to be better defined. In this paper an overview of future EOR scope taking into consideration the current oil economic climate is developed and presented

The Scope of Practice of Occupational Therapy in U.S. Criminal Justice Settings.

Science.gov (United States)

Muñoz, Jaime P; Moreton, Emily M; Sitterly, Audra M

2016-09-01

In the past 40 years, prison populations in the U.S. have nearly quadrupled while funding for rehabilitation, education and other programmes has been cut. Despite accounting for a small fraction of the world's population more than 20% of the worlds incarcerated population is in the U.S. and the rate of recidivism remains alarmingly high. Occupational therapists have the capability to play a significant role in addressing the needs of persons within the criminal justice system. However, the profession has been slow to delineate of the role occupational therapy within criminal justice settings. This study sought to provide a descriptive analysis of current occupational therapy roles and practices within the U.S. criminal justice system. Using survey research methods, the researchers collected data from respondents (N = 45; Response Rate + 51.7%) to establish a baseline of the scope of practices employed by occupational therapists working in the U.S. criminal justice system. U.S. practitioners work within institutional and community based criminal justice settings. Primary practice models, assessments and group interventions were catalogued. Respondents strongly valued the creation of networking to build the professions' presence within criminal justice settings. Occupational therapy in the criminal justice system remains an emerging practice arena. Understanding the current scope of practice in the U.S. and creating a mechanism for collaboration may help increase the depth, breadth and overall growth of the profession's role in these settings. The sampling method does not guarantee a representative sample of the population and is limited to practice within the United States. Survey design may not have allowed for respondents to fully describe their practice experiences. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Exploring the training and scope of practice of GPs in England, Germany and Spain.

Science.gov (United States)

Glonti, Ketevan; Struckmann, Verena; Alconada, Alvaro; Pettigrew, Luisa M; Hernandez-Santiago, Virginia; Minue, Sergio; Risso-Gill, Isabelle; McKee, Martin; Legido-Quigley, Helena

2018-03-22

To explore general practitioner (GP) training, continuing professional development, scope of practice, ethical issues and challenges in the working environment in three European countries. Qualitative study of 35 GPs from England, Germany and Spain working in urban primary care practices. Participants were recruited using convenience and snowball sampling techniques. Semi-structured interviews were recorded, transcribed and analysed by four independent researchers adopting a thematic approach. Entrance to and length of GP training differ between the three countries, while continuing professional development is required in all three, although with different characteristics. Key variations in the scope of practice include whether there is a gatekeeping role, whether GPs work in multidisciplinary teams or singlehandedly, the existence of appraisal processes, and the balance between administrative and clinical tasks. However, similar challenges, including the need to adapt to an ageing population, end-of-life care, ethical dilemmas, the impact of austerity measures, limited time for patients and gaps in coordination between primary and secondary care are experienced by GPs in all three countries. Primary health care variations have strong historical roots, derived from the different national experiences and the range of clinical services delivered by GPs. There is a need for an accessible source of information for GPs themselves and those responsible for safety and quality standards of the healthcare workforce. This paper maps out the current situation before Brexit is being implemented in the UK which could see many of the current EU arrangements and legislation to assure professional mobility between the UK and the rest of Europe dismantled. Copyright © 2017. Publicado por Elsevier España, S.L.U.

Voyager Interactive Web Interface to EarthScope

Science.gov (United States)

Eriksson, S. C.; Meertens, C. M.; Estey, L.; Weingroff, M.; Hamburger, M. W.; Holt, W. E.; Richard, G. A.

2004-12-01

tectonic processes are reflected in observed geophysical phenomena. Constructing maps by controlling map parameters and answering open-ended questions which describe, compare relationships, and work with both observed and model data, promote conceptual understanding of plate tectonics and related processes. The goals of curricular development emphasize inquiry, development of critical thinking skills, and student-centered interests. Custom editions of the map utility have been made as the "Jules Verne Voyager" and "Voyager Junior", for the International Lithosphere Project's "Global Strain Rate Map", and for EarthScope Education and Outreach as "EarthScope Voyager Jr.". For the latter, a number of EarthScope-specific features have been added, including locations of proposed USArray (seismic), Plate Boundary Observatory (geodetic), and San Andreas Fault Observatory at Depth sites, plus detailed maps and geographically referenced examples of EarthScope-related scientific investigations. As EarthScope develops, maps will be updated in `real time' so that students of all ages can use the data in formal and informal educational settings.

The High/Scope Report. Number Four.

Science.gov (United States)

Silverman, Charles, Ed.

This report provides articles on several topics related to the education of young children. In the introduction High/Scope President David P. Weikart suggests that public investment in preschool education is a wise and economically sound social policy. New studies of the long term effects of preschool are demonstrating the staying power of early…