Chronic Stress Induces Structural Alterations in Splenic Lymphoid Tissue That Are Associated with Changes in Corticosterone Levels in Wistar-Kyoto Rats

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María Eugenia Hernandez

2013-01-01

Full Text Available Major depressive disorder patients present chronic stress and decreased immunity. The Wistar-Kyoto rat (WKY is a strain in which the hypothalamic-pituitary-adrenal axis is overactivated. To determine whether chronic stress induces changes in corticosterone levels and splenic lymphoid tissue, 9-week-old male rats were subject to restraint stress (3 h daily, chemical stress (hydrocortisone treatment, 50 mg/Kg weight, mixed stress (restraint plus hydrocortisone, or control treatment (without stress for 1, 4, and 7 weeks. The serum corticosterone levels by RIA and spleens morphology were analyzed. Corticosterone levels as did the structure, size of the follicles and morphology of the parenchyma (increase in red pulp in the spleen, varied depending on time and type of stressor. These changes indicate that chronic stress alters the immune response in the spleen in WKY rats by inducing morphological changes, explaining in part the impaired immunity that develops in organisms that are exposed to chronic stress.

Opiate antagonist binding sites in discrete brain regions of spontaneously hypertensive and normotensive Wistar-Kyoto rats

Energy Technology Data Exchange (ETDEWEB)

Rahmani, N.H.; Gulati, A.; Bhargava, H.N. (Univ. of Illinois, Chicago (USA))

1991-01-01

The binding of {sup 3}H-naltrexone, an opiate receptor antagonist, to membranes of discrete brain regions and spinal cord of 10 week old spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WKY) rats was determined. The brain regions examined were hypothalamus, amygdala, hippocampus, corpus striatum, pons and medulla, midbrain and cortex. {sup 3}H-Naltrexone bound to membranes of brain regions and spinal cord at a single high affinity site with an apparent dissociation constant value of 3 nM. The highest density of {sup 3}H-naltrexone binding sites were in hippocampus and lowest in the cerebral cortex. The receptor density (B{sub max}value) and apparent dissociation constant (K{sub d} value) values of {sup 3}H-naltrexone to bind to opiate receptors on the membranes of amygdala, hippocampus, corpus striatum, pons and medulla, midgrain, cortex and spinal cord of WKY and SHR rates did not differ. The B{sub max} value of {sup 3}H-naltrexone binding to membranes of hypothalamus of SHR rates was 518% higher than WKY rats but the K{sub d} values in the two strains did not differ. It is concluded that SHR rats have higher density of opiate receptors labeled with {sup 3}H-naltrexone in the hypothalamus only, in comparison with WKY rats, and that such a difference in the density of opiate receptors may be related to the elevated blood pressure in SHR rats.

Long-Term Effects of Chronic Oral Ritalin Administration on Cognitive and Neural Development in Adolescent Wistar Kyoto Rats

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Jennifer L. Cornish

2012-09-01

Full Text Available The diagnosis of Attention Deficit Hyperactivity Disorder (ADHD often results in chronic treatment with psychostimulants such as methylphenidate (MPH, Ritalin®. With increases in misdiagnosis of ADHD, children may be inappropriately exposed to chronic psychostimulant treatment during development. The aim of this study was to assess the effect of chronic Ritalin treatment on cognitive and neural development in misdiagnosed “normal” (Wistar Kyoto, WKY rats and in Spontaneously Hypertensive Rats (SHR, a model of ADHD. Adolescent male animals were treated for four weeks with oral Ritalin® (2 × 2 mg/kg/day or distilled water (dH2O. The effect of chronic treatment on delayed reinforcement tasks (DRT and tyrosine hydroxylase immunoreactivity (TH-ir in the prefrontal cortex was assessed. Two weeks following chronic treatment, WKY rats previously exposed to MPH chose the delayed reinforcer significantly less than the dH2O treated controls in both the DRT and extinction task. MPH treatment did not significantly alter cognitive performance in the SHR. TH-ir in the infralimbic cortex was significantly altered by age and behavioural experience in WKY and SHR, however this effect was not evident in WKY rats treated with MPH. These results suggest that chronic treatment with MPH throughout adolescence in “normal” WKY rats increased impulsive choice and altered catecholamine development when compared to vehicle controls.

Morphometric analysis of the phrenic nerve in male and female Wistar-Kyoto (WKY and spontaneously hypertensive rats (SHR

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A.R. Rodrigues

2011-06-01

Full Text Available Ventilatory differences between rat strains and genders have been described but the morphology of the phrenic nerve has not been investigated in spontaneously hypertensive (SHR and normotensive Wistar-Kyoto (WKY rats. A descriptive and morphometric study of the phrenic nerves of male (N = 8 and female (N = 9 SHR, and male (N = 5 and female (N = 6 WKY is presented. After arterial pressure and heart rate recordings, the phrenic nerves of 20-week-old animals were prepared for epoxy resin embedding and light microscopy. Morphometric analysis performed with the aid of computer software that took into consideration the fascicle area and diameter, as well as myelinated fiber profile and Schwann cell nucleus number per area. Phrenic nerves were generally larger in males than in females on both strains but larger in WKY compared to SHR for both genders. Myelinated fiber numbers (male SHR = 228 ± 13; female SHR = 258 ± 4; male WKY = 382 ± 23; female WKY = 442 ± 11 for proximal right segments and density (N/mm²; male SHR = 7048 ± 537; female SHR = 10355 ± 359; male WKY = 9457 ± 1437; female WKY = 14351 ± 1448 for proximal right segments were significantly larger in females of both groups and remarkably larger in WKY than SHR for both genders. Strain and gender differences in phrenic nerve myelinated fiber number are described for the first time in this experimental model of hypertension, indicating the need for thorough functional studies of this nerve in male and female SHR.

The Kyoto protocol development; La viabilite du protocole de Kyoto

Energy Technology Data Exchange (ETDEWEB)

Cooper, R. [Harvard Univ., Barrow, AK (United States); Guesneris, R. [College de France, 75 - Paris (France)

2002-04-01

From the author R. Cooper point of view the Kyoto Protocol is a flawed concept. The reasons for dropping Kyoto are presented in this paper insisting that rejecting Kyoto not means to imply that global climate change is not a serious problem. After a presentation of the US policy facing the Climatic Change, some concluding propositions are proposed. (A.L.B.)

GAME ANALYSIS OF KYOTO AND POST-KYOTO SCHEMES

Energy Technology Data Exchange (ETDEWEB)

Haruo Imai [Kyoto Institute of Economic Research, Kyoto University, Sakyo, Kyoto (Japan)

2008-09-30

Kyoto protocol, put in force in Feb. 2005, is criticized from both sides, those demanding a stricter target for GHG (green house gas) emission reduction on the one side, and those claiming for more flexible and comprehensive controls of the emission on the other side, for its modest target and narrow coverage. Even though its value could be that of a mere precedent and experimentation, Kyoto protocol includes very special experimentation to assist the world wide cooperation for a mitigation of climate change, i.e. the introduction of three mechanisms, emissions trading, joint implementation, and clean development mechanism (CDM). Together, they are called Kyoto mechanisms. Evaluation of mechanisms is one important role of microeconomics and the game theory is a major tool for it. We shall scrutinize these mechanisms from such viewpoint. A special attention is placed on CDM, as it is the novel mechanism introduced by Kyoto protocol, and gives a unique link between Annex I nations (mostly developed countries) and non-Annex I nations (mostly developing countries). Next, we examine some of the currently proposed schemes after 2013, the post Kyoto schemes. One of the chief issues is the possibility of making a comprehensive agreement including both the USA and large developing countries with rapidly increasing emission levels of GHG like China and India. Adding to these, not only the proposed schemes themselves, but the process of negotiation itself inspired several researches in cooperative game theory and in particular, coalition formation theory. We shall touch upon this issue separately, and examine how successfully they predicted the outcome leading to Kyoto, retrospectively. Finally, we end our discussion with a brief consideration over the underlining normative argument concerning these schemes.

LDH and G-6PDH activities in the ovaries of adult female Wistar rats ...

African Journals Online (AJOL)

The present study was designed to evaluate the effects of aqueous extracts of neem (Azadirachta Indica) leaves (which have been documented for its antifertility effect on experimental animals) on glucose-6-phosphate dehydrogenase (G-6PDH) and lactate dehydrogenase (LDH) levels in the ovaries of adult female wistar ...

Differential Responses to Blood Pressure and Oxidative Stress in Streptozotocin-Induced Diabetic Wistar-Kyoto Rats and Spontaneously Hypertensive Rats: Effects of Antioxidant (Honey) Treatment

Science.gov (United States)

Erejuwa, Omotayo O.; Sulaiman, Siti A.; Wahab, Mohd Suhaimi Ab; Sirajudeen, Kuttulebbai N. S.; Salleh, Md Salzihan Md; Gurtu, Sunil

2011-01-01

Oxidative stress is implicated in the pathogenesis and/or complications of hypertension and/or diabetes mellitus. A combination of these disorders increases the risk of developing cardiovascular events. This study investigated the effects of streptozotocin (60 mg/kg; ip)-induced diabetes on blood pressure, oxidative stress and effects of honey on these parameters in the kidneys of streptozotocin-induced diabetic Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR). Diabetic WKY and SHR were randomized into four groups and received distilled water (0.5 mL) and honey (1.0 g/kg) orally once daily for three weeks. Control SHR had reduced malondialdehyde (MDA) and increased systolic blood pressure (SBP), catalase (CAT) activity, and total antioxidant status (TAS). SBP, activities of glutathione peroxidase (GPx) and glutathione reductase (GR) were elevated while TAS was reduced in diabetic WKY. In contrast, SBP, TAS, activities of GPx and GR were reduced in diabetic SHR. Antioxidant (honey) treatment further reduced SBP in diabetic SHR but not in diabetic WKY. It also increased TAS, GSH, reduced glutathione (GSH)/oxidized glutathione (GSSG) ratio, activities of GPx and GR in diabetic SHR. These data suggest that differences in types, severity, and complications of diseases as well as strains may influence responses to blood pressure and oxidative stress. PMID:21673929

Effect of 1,25(OH)2 vitamin D3 and ionized Ca2+ on 45Ca uptake by primary cultures of aortic myocytes of spontaneously hypertensive and Wistar Kyoto normotensive rats

International Nuclear Information System (INIS)

Bukoski, R.D.; Xue, H.; McCarron, D.A.

1987-01-01

The effect of several regulators of whole animal Ca 2+ homeostasis on 45 Ca uptake by primary cultures of aortic myocytes isolated from spontaneously hypertensive (SHR) and normotensive Wistar Kyoto (WKY) rats was examined. Exposure of confluent cells to 1.0, 1.25 or 1.50 mM ionized Ca 2+ in serum-free medium for seven days resulted in increased 45 Ca uptake at the higher concentrations of Ca 2+ in cells of the SHR but not the WKY. 1,25 (OH)2 vitamin D3 (1 ng/ml) for 7 days caused enhanced influx in cells from both the SHR and WKY while parathyroid hormone (1-34) (1 ng/ml) was without effect. The data indicate that humoral factors that serve to regulate whole animal Ca 2+ homeostasis may also play a role in the regulation of Ca 2+ metabolism of the vascular smooth muscle cell

Astrocytes from adult Wistar rats aged in vitro show changes in glial functions.

Science.gov (United States)

Souza, Débora Guerini; Bellaver, Bruna; Raupp, Gustavo Santos; Souza, Diogo Onofre; Quincozes-Santos, André

2015-11-01

Astrocytes, the most versatile cells of the central nervous system, play an important role in the regulation of neurotransmitter homeostasis, energy metabolism, antioxidant defenses and the anti-inflammatory response. Recently, our group characterized cortical astrocyte cultures from adult Wistar rats. In line with that work, we studied glial function using an experimental in vitro model of aging astrocytes (30 days in vitro after reaching confluence) from newborn (NB), adult (AD) and aged (AG) Wistar rats. We evaluated metabolic parameters, such as the glucose uptake, glutamine synthetase (GS) activity, and glutathione (GSH) content, as well as the GFAP, GLUT-1 and xCT expression. AD and AG astrocytes take up less glucose than NB astrocytes and had decreased GLUT1 expression levels. Furthermore, AD and AG astrocytes exhibited decreased GS activity compared to NB cells. Simultaneously, AD and AG astrocytes showed an increase in GSH levels, along with an increase in xCT expression. NB, AD and AG astrocytes presented similar morphology; however, differences in GFAP levels were observed. Taken together, these results improve the knowledge of cerebral senescence and represent an innovative tool for brain studies of aging. Copyright © 2015 Elsevier Ltd. All rights reserved.

How to make progress post-Kyoto

Energy Technology Data Exchange (ETDEWEB)

NONE

2003-07-01

This document provides papers presented during the workshop on ''how to make progress post-Kyoto'', hold at the French Institute of International Relations (IFRI) in Paris on march 19, 2003. The following topics were presented: reflections on Kyoto, guidance for the future, how to make progress post-kyoto, the lessons from the past; the Bonn voyage; US climate policy after Kyoto, elements of success; preparing for widening and deepening the kyoto protocol; capping emissions and costs; absolute versus intensity-based emissions caps; intensity targets in perspective; negotiating commitments for further emission reductions; exploring new tools; defining meaningful participation of developing countries in climate change mitigation; economic and environmental effectiveness of a technology-based climate regime; US participation in the linkage between research and development and climate cooperation; designing a technology strategy; ''greening'' economic development; some critical comments post-Kyoto; the foreign policy perspective of climate negotiations; Kyoto and the double spiral; burden-sharing rules for stabilizing greenhouse gas concentrations and their equity implications. (A.L.B.)

Ultrafine Particulate Matter Combined With Ozone Exacerbates Lung Injury in Mature Adult Rats With Cardiovascular Disease.

Science.gov (United States)

Wong, Emily M; Walby, William F; Wilson, Dennis W; Tablin, Fern; Schelegle, Edward S

2018-05-01

Particulate matter (PM) and ozone (O3) are dominant air pollutants that contribute to development and exacerbation of multiple cardiopulmonary diseases. Mature adults with cardiovascular disease (CVD) are particularly susceptible to air pollution-related cardiopulmonary morbidities and mortalities. The aim was to investigate the biologic potency of ultrafine particulate matter (UFPM) combined with O3 in the lungs of mature adult normotensive and spontaneously hypertensive (SH) Wistar-Kyoto rats. Conscious, mature adult male normal Wistar-Kyoto (NW) and SH rats were exposed to one of the following atmospheres: filtered air (FA); UFPM (∼ 250 μg/m3); O3 (1.0 ppm); or UFPM + O3 (∼ 250 μg/m3 + 1.0 ppm) combined for 6 h, followed by an 8 h FA recovery period. Lung sections were evaluated for lesions in the large airways, terminal bronchiolar/alveolar duct regions, alveolar parenchyma, and vasculature. NW and SH rats were similarly affected by the combined-pollutant exposure, displaying severe injury in both large and small airways. SH rats were particularly susceptible to O3 exposure, exhibiting increased injury scores in terminal bronchioles and epithelial degeneration in large airways. UFPM-exposure groups had minimal histologic changes. The chemical composition of UFPM was altered by the addition of O3, indicating that ozonolysis promoted compound degradation. O3 increased the biologic potency of UFPM, resulting in greater lung injury following exposure. Pathologic manifestations of CVD may confer susceptibility to air pollution by impairing normal lung defenses and responses to exposure.

How to make progress post-Kyoto

Energy Technology Data Exchange (ETDEWEB)

NONE

2003-07-01

This document provides papers presented during the workshop on ''how to make progress post-Kyoto'', hold at the French Institute of International Relations (IFRI) in Paris on march 19, 2003. The following topics were presented: reflections on Kyoto, guidance for the future, how to make progress post-kyoto, the lessons from the past; the Bonn voyage; US climate policy after Kyoto, elements of success; preparing for widening and deepening the kyoto protocol; capping emissions and costs; absolute versus intensity-based emissions caps; intensity targets in perspective; negotiating commitments for further emission reductions; exploring new tools; defining meaningful participation of developing countries in climate change mitigation; economic and environmental effectiveness of a technology-based climate regime; US participation in the linkage between research and development and climate cooperation; designing a technology strategy; ''greening'' economic development; some critical comments post-Kyoto; the foreign policy perspective of climate negotiations; Kyoto and the double spiral; burden-sharing rules for stabilizing greenhouse gas concentrations and their equity implications. (A.L.B.)

Postnatal exposure to PCB 153 and PCB 180, but not to PCB 52, produces changes in activity level and stimulus control in outbred male Wistar Kyoto rats

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Walaas S

2011-05-01

Full Text Available Abstract Background Polychlorinated biphenyls (PCBs are a class of organic compounds that bioaccumulate due to their chemical stability and lipophilic properties. Humans are prenatally exposed via trans-placental transfer, through breast milk as infants, and through fish, seafood and fatty foods as adolescents and adults. Exposure has several reported effects ranging from developmental abnormalities to cognitive and motor deficiencies. In the present study, three experimental groups of rats were orally exposed to PCBs typically found in human breast milk and then behaviorally tested for changes in measures of stimulus control (percentage lever-presses on the reinforcer-producing lever, activity level (responses with IRTs > 0.67 s, and responses with short IRTs ( Methods Male offspring from Wistar Kyoto (WKY/NTac dams purchased pregnant from Taconic Farms (Germantown, NY were orally given PCB at around postnatal day 8, 14, and 20 at a dose of 10 mg/kg body weight at each exposure. Three experimental groups were exposed either to PCB 52, PCB 153, or PCB 180. A fourth group fed corn oil only served as controls. From postnatal day 25, for 33 days, the animals were tested for behavioral changes using an operant procedure. Results PCB exposure did not produce behavioral changes during training when responding was frequently reinforced using a variable interval 3 s schedule. When correct responses were reinforced on a variable interval 180 s schedule, animals exposed to PCB 153 or PCB 180 were less active than controls and animals exposed to PCB 52. Stimulus control was better in animals exposed to PCB 180 than in controls and in the PCB 52 group. Also, the PCB 153 and PCB 180 groups had fewer responses with short IRTs than the PCB 52 group. No effects of exposure to PCB 52 were found when compared to controls. Conclusions Exposure to PCBs 153 and 180 produced hypoactivity that continued at least five weeks after the last exposure. No effects of

Urban landscape of Okazaki in Kyoto

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Olimpia Niglio

2015-12-01

Full Text Available Kyoto has been the capital of Japan from 794 until when the capital has moved in 1868 to Tokyo with the end of Tokugawa Shoguns and the beginning of the Meiji Restoration. The loss of the seat of government was a shock to citizens of Kyoto as the city had been the Imperial and Cultural center of the nation for over 1.000 years. The combination of the court and the great temples had enlivened and enriched the life of the city. At the beginning of the founding of the capital, in the Heian period (794-1185 to east of Kyoto, was built a noble and religious place. This area is Okazaki. Here the Emperor Kammu (736-805 had created the city of Heian-kyo (Kyoto in 794. This area was full of Temples and Shrines. Only in the Edo period (1603-1867 Okazaki area assumed the role of suburban agricultural zone which provided the food production to the urban habitants. But after the Meiji Restoration (1868-1912, the role of Okazaki area changes completely. In 1885, Kyoto prefecture started the great public canalization project as the water supply between Kyoto and Otsu of Shiga prefecture. Kyoto prefecture also planed the industrial district construction in Okazaki area. From the late nineteenth century Okazaki area became a symbol of the modernization of Kyoto city. This contribution intends to analyze the urban landscape composed of the different styles of architecture especially constructed after the Meiji period (1868-1912. Tangible and intangible signs remained as modern gardens, significant museums and cultural institutions among the ancient temples provide opportunities to reflect on the important role of suburban area of the historic city. These studies are supported by archival documents and by current measures and policies for landscape conservation by Kyoto Municipality.

The Kyoto Mechanisms and Technological Innovation

DEFF Research Database (Denmark)

Lund, Henrik

2003-01-01

Climate change response, including implementation of the Kyoto targets as the first step, calls for technological innovation of future sustainable energy systems. One of the important agreements in several declarations, including the Kyoto protocol, has been to promote and coordinate...... the collaboration between the countries in the necessary technological development. The paper encourage that the Kyoto mechanisms will be used for acceleration of the necessary technical innovation in Denmark....

Effect of γ-aminobutyric acid and nattokinase-enriched fermented beans on the blood pressure of spontaneously hypertensive and normotensive Wistar-Kyoto rats.

Science.gov (United States)

Suwanmanon, Kanintra; Hsieh, Pao-Chuan

2014-12-01

In this study we have evaluated the changes in arterial blood pressure in spontaneously hypertensive rats (SHR) caused by the short-term intake of Bacillus subtilis B060-fermented beans with significant γ-aminobutyric acid (GABA) and nattokinase activity. After being weaned, 7-week-old male SHR and 7-week-old male Wistar-Kyoto (WKY) rats were randomized into seven groups. Until the 8 th week of life, the rats in each group were given one of the following: Group 1, high dose of GABA and nattokinase in the SHR (SHD); Group 2, medium dose of GABA and nattokinase in the SHR (SMD); Group 3, low dose of GABA and nattokinase in the SHR (SLD); Group 4, negative control in the SHR (SD); Group 5, positive control in the SHR (SM); Group 6, high dose of GABA and nattokinase in the WKY (WHD); and Group 7, negative control in the WKY (WD). Distilled water served as the negative control, and captopril (50 mg/kg), a known ACE inhibitor, served as the positive control. Systolic blood pressure and diastolic blood pressure values were measured weekly from the 8 th week to the 16 th week of life using the tail-cuff method. A definite decrease in systolic and diastolic blood pressure values could be observed in the rats treated with captopril and in the rats that received GABA and nattokinase. The greatest antihypertensive effect was observed when the pharmacological treatment was administered. The effect of the daily intake of fermented beans containing GABA and nattokinase may be helpful in controlling blood pressure levels in hypertensive model animals. The fermentation of beans with B. subtilis B060 may therefore constitute a successful strategy for producing a functional food with antihypertensive activity. Copyright © 2014. Published by Elsevier B.V.

Beta Cell Workshop 2013 Kyoto

DEFF Research Database (Denmark)

Heller, R Scott; Madsen, Ole D; Nielsen, Jens Høiriis

2013-01-01

The very modern Kyoto International Conference Center provided the site for the 8th workshop on Beta cells on April 23-26, 2013. The preceding workshops were held in Boston, USA (1991); Kyoto, Japan (1994); Helsingør, Denmark (1997); Helsinki, Finland (2003); El Perello, Spain (2006); Peebles...

HISTOLOGICAL STUDIES OF THE EFFECTS OF RED PEPPER ON THE STOMACH OF ADULT WISTAR RATS

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Josiah O. Adjene

2007-01-01

Full Text Available Histological effects of red pepper commonly used as spice in food on the stomach of adult wistar rats were carefully investigated. The rats of both sexes (n=24, average weight of 200g were randomly assigned into two treatments (n=16 and control (n=6 groups. The rats in the treatments groups received 1g and 2g of red pepper thoroughly mixed with 20g of their feeds for 7 and 14 days, while the control rats received equal amounts of feeds without the red pepper added. The rats were fed with grower's mash purchased from Edo feeds and flour mill Ltd, Ewu, Edo State and were given water liberally. The rats were sacrificed on day eight and fifteen of the experiment respectively.The stomach was carefully dissected out and quickly fixed in 10% formol saline for routine histological procedure after H & E method.The histological findings after H&E methods indicated that the treated sections of the stomach showed some level of cellular hypertrophy, congestion of blood vessels degenerative changes disruption and distortion of the cytoarchitecture of the stomach.These findings indicate that red pepper may have some deleterious effects on the microanatomy of the stomach of adult wistar rat at higher doses. It is recommended that further studies aimed at corroborating these findings be carried out.

Histological Studies Of The Pancreas Of Wistar Rats Following ...

African Journals Online (AJOL)

This study was to find the probable effect of Nicotiana tabacum (snuff) on the histological features of the pancreas of adult wistar rats. Nicotiana tabacum is a product of smokeless tobacco which contains many toxins and high levels of nicotine. Twenty male wistar rats weighing 200-210g were used for this study. The control ...

Carbon credits after Kyoto

International Nuclear Information System (INIS)

Anon.

1998-01-01

In the Kyoto Protocol to the FCCC three different forms of GHG emission reduction titles through market-based international cooperation are defined: emission reduction units under Article 6; certified emission reductions in the framework of the Clean Development Mechanism (CDM) under Article 12; and emissions trading under Article 17. Although defined under different Articles in the Protocol, it seems reasonable to assume that the three mechanisms will not operate separately. After CoP3 the author registered several comments, opinions and concerns related to the flexibility provisions under the Kyoto Protocol

The Effects of Early-Life Predator Stress on Anxiety- and Depression-Like Behaviors of Adult Rats

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Lu-jing Chen

2014-01-01

Full Text Available Childhood emotional trauma contributes significantly to certain psychopathologies, such as post-traumatic stress disorder. In experimental animals, however, whether or not early-life stress results in behavioral abnormalities in adult animals still remains controversial. Here, we investigated both short-term and long-term changes of anxiety- and depression-like behaviors of Wistar rats after being exposed to chronic feral cat stress in juvenile ages. The 2-week predator stress decreased spontaneous activities immediately following stress but did not increase depression- or anxiety-like behaviors 4 weeks after the stimulation in adulthood. Instead, juvenile predator stress had some protective effects, though not very obvious, in adulthood. We also exposed genetic depression model rats, Wistar Kyoto (WKY rats, to the same predator stress. In WKY rats, the same early-life predator stress did not enhance anxiety- or depression-like behaviors in both the short-term and long-term. However, the stressed WKY rats showed slightly reduced depression-like behaviors in adulthood. These results indicate that in both normal Wistar rats and WKY rats, early-life predator stress led to protective, rather than negative, effects in adulthood.

The Effects of Early-Life Predator Stress on Anxiety- and Depression-Like Behaviors of Adult Rats

Science.gov (United States)

Chen, Lu-jing; Shen, Bing-qing; Liu, Dan-dan; Li, Sheng-tian

2014-01-01

Childhood emotional trauma contributes significantly to certain psychopathologies, such as post-traumatic stress disorder. In experimental animals, however, whether or not early-life stress results in behavioral abnormalities in adult animals still remains controversial. Here, we investigated both short-term and long-term changes of anxiety- and depression-like behaviors of Wistar rats after being exposed to chronic feral cat stress in juvenile ages. The 2-week predator stress decreased spontaneous activities immediately following stress but did not increase depression- or anxiety-like behaviors 4 weeks after the stimulation in adulthood. Instead, juvenile predator stress had some protective effects, though not very obvious, in adulthood. We also exposed genetic depression model rats, Wistar Kyoto (WKY) rats, to the same predator stress. In WKY rats, the same early-life predator stress did not enhance anxiety- or depression-like behaviors in both the short-term and long-term. However, the stressed WKY rats showed slightly reduced depression-like behaviors in adulthood. These results indicate that in both normal Wistar rats and WKY rats, early-life predator stress led to protective, rather than negative, effects in adulthood. PMID:24839560

Kyoto Protocol: trade versus the environment

International Nuclear Information System (INIS)

Loose, H.

2001-01-01

Could the signatories to the Kyoto Protocol find themselves up against the WTO? This paper examines how the climate change agreement could conflict with trade rules, and shows that there are potentially serious conflicts in the interface between the WTO and the Kyoto Protocol. It argues for dialogue and debate before it is too late. (author)

Testis evaluation of adult Wistar rats after neonatal treatment with fluoxetine - doi: 10.4025/actascibiolsci.v35i1.10946

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Bruno Mendes Tenorio

2012-12-01

Full Text Available In current assay the serotoninergic system in newly-born Wistar rats underwent pharmacological modification by fluoxetine, a selective serotonin reuptake inhibitor (SSRI, to investigate its repercussion on testicular parameters in adult animals. Thirty animals were distributed according to treatment: control animals (n = 6, animals treated with 1 mg kg-1 (n = 6, 5 mg kg-1 (n = 6, 10 mg kg-1 (n = 6 and 20 mg kg-1 (n = 6 of fluoxetine (IP. When 150 days old, the animals were anesthetized and perfused intra-cardiacally with fixative solution. Testes were routinely processed for inclusion in plastic resin (methacrylate glycol. Further, 4 µm-thick histological sections were stained with toluidine blue/sodium borate 1% and analyzed histometrically. Pharmacological intervention on the serotoninergic system during the postnatal period of the testes development in Wistar rats with fluoxetine chlorohydrate reduced parameters, such as testicular weight, testis liquid weight and seminiferous tubules diameter. However, testicular parameters, such as daily sperm production (DSP, spermatogenesis efficiency (DSP/g/testis and cell population in stage VII of adult animals, were not influenced by fluoxetine chlorohydrate usage during neonatal period. Results show that administration of fluoxetine during 21 days after birth may induce adverse changes in the spermatogenesis of adult rats.  

HISTOLOGICAL STUDIES OF THE EFFECTS OF MONOSODIUM GLUTAMATE ON THE INFERIOR COLLICULUS OF ADULT WISTAR RATS.

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A.O. Eweka.

2008-01-01

Full Text Available Histological effects of Monosodium glutamate (MSG commonly used as food additive on the inferior colliculus (IC of adult Wistar rats were carefully studied. The rats of both sexes (n=24, average weight of 185g were randomly assigned into two treatments (n=16 and control (n=8 groups. The rats in the treatment groups received 3g and 6g of MSG thoroughly mixed with their feeds for fourteen days, while the control rats received equal amounts of feeds without MSG added. The rats were fed with growers' mash purchased from Edo Feeds and Flour Mill Ltd, Ewu, Edo State and were given water liberally. The rats were sacrificed on day fifteen of the experiment. The inferior colliculus was carefully dissected out and quickly fixed in 10% formal saline for routine histological study after H&E method.The histological findings after H&E methods indicated that the treated sections of the inferior colliculus showed some cellular degenerative changes, cellular hypertrophy, and autophagic vacuoles with some intercellular vacuolations appearing in the stroma, and some degree of neuronal hypertrophy when compared to the control sections.These findings indicate that MSG consumption may have a deleterious effect on the neurons of the inferior colliculus (IC. MSG may probably have adverse effects on the auditory sensibilities by its deleterious effects on the nerve cells of the IC of adult Wistar rats. It is recommended that further studies aimed at corroborating these observations be carried out.

HISTOLOGICAL EFFECTS OF CHRONIC CONSUMPTION OF NUTMEG ON THE LATERAL GENICULATE BODY OF ADULT WISTAR RATS.

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J.O. Adjene

2010-01-01

Full Text Available The effects of chronic consumption of nutmeg commonly used as a spice in various dishes, as components of teas and soft drinks or mixed in milk and alcohol on the lateral geniculate body of adult wistar rats was studied.The rats of both sexes, with average weight of 200g were randomly assigned into treatment and control groups. The rats in the treatment group (n=8 received 2g of nutmeg thoroughly mixed with the feeds on a daily basis for thirty-two days. The control group (n=8 received equal amount of feeds daily without nutmeg added for thirty-two days. The growers mash feeds was obtained from Edo Feeds and Flour Mill Limited, Ewu, Edo State, Nigeria and the rats were given water liberally. The rats were sacrificed on the thirty-three day of the experiment. The lateral geniculate body was carefully dissected out and quickly fixed in 10% formal saline for histological study.The findings indicate that rats in the treated group showed some cellular degenerative changes like sparse cellular population, pyknotic nuclei with some microcystic changes, edema and vacuolations in the stroma of the treated lateral geniculate body as compared to that of the control group.Chronic consumption of nutmeg may therefore have an adverse effect on the visual sensibilities by affecting the microanatomy of the lateral geniculate body of adult wistar rats. It is recommended for further studies aimed at corroborating these observations.

The Kyoto mechanisms and technological innovation

International Nuclear Information System (INIS)

Lund, Henrik

2006-01-01

Climate change response, including the implementation of the Kyoto targets as the first step, calls for technological innovation of future sustainable energy systems. Based on the Danish case, this paper evaluates the type of technological change necessary. During a period of 30 years, Denmark managed to stabilize primary energy supply, and CO 2 emissions decreased by 10%, during a period of 20 years. However, after the introduction of the Kyoto Mechanisms, Denmark has changed its strategy. Instead of continuing the domestic CO 2 emission controls, Denmark plans to buy CO 2 reductions in other countries. Consequently, the innovative technological development has changed. This paper evaluates the character of such change and makes preliminary recommendations for policies to encourage the use of the Kyoto Mechanisms as an acceleration of the necessary technological innovation. (author)

Negative Effect of Zinc on Testes, Testosterone and Gonadotrophins Levels in Adult Male Wistar Rats

Directory of Open Access Journals (Sweden)

D. Sohrabi

2008-10-01

Full Text Available Background and ObjectivesThe toxic effects of zinc leading to sebaceous gland closure, skin eczema and blister have been previously demonstrated in other studies. The aim of this study is to determine the chronic effects of zinc chloride (ZnCl2 on testicular tissues, testosterone and gonadotrophins in adult male Wistar rats.Methods Twenty four Adult male Wistar rats were divided in to two groups of study and control with each group consisting of 12 rats. Study group rats received 10 mg/kg interaperitoneal Zinc chloride in normal saline (N.S every other day for 30 days. Control group rats received N.S during this time. Blood sample for hormonal evaluation were collected from hearts of these rats. The rats were destroyed and their testes were removed and fixed in a 10% formaldehyde and glutaraldehyde solution.ResultsThe results of this study showed a significant decrease in the level of LH and testosterone hormone among the rats in the study group compared to the control group with p< 0.001 and p< 0.01 respectively. Study of fine structure of testicular cells and tissues in the study group rats revealed swelling of mitochondria, increase in smooth endoplasmic reticulum vacuolization and lysosomic granules (Autophagic vacuoles in cytosol of their germinal cells.ConclusionBased on the results of this study consumption of large amount of compounds which contain zinc should be controlled and limited among men. There is a need for further studies to evaluate and determine the reversibility of most hormonal and physiological changes due to usage of zinc containing compounds.Keywords: Zinc Chloride; Testis; Testosterone; Gonadotrophins

Global post-Kyoto scenario analyses at PSI

Energy Technology Data Exchange (ETDEWEB)

Kypreos, S [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

1999-08-01

Scenario analyses are described here using the Global MARKAL-Macro Trade (GMMT) model to study the economic implications of the Kyoto Protocol to the UN Convention on Climate change. Some conclusions are derived in terms of efficient implementations of the post-Kyoto extensions of the Protocol. (author) 2 figs., 5 refs.

Global post-Kyoto scenario analyses at PSI

International Nuclear Information System (INIS)

Kypreos, S.

1999-01-01

Scenario analyses are described here using the Global MARKAL-Macro Trade (GMMT) model to study the economic implications of the Kyoto Protocol to the UN Convention on Climate change. Some conclusions are derived in terms of efficient implementations of the post-Kyoto extensions of the Protocol. (author) 2 figs., 5 refs

From Kyoto to Copenhagen: the carbon markets expansion

International Nuclear Information System (INIS)

Alberola, Emilie; Fages, Emmanuel

2009-01-01

The article examines the development of carbon markets in the world. Such markets are the main economic instrument of the international climate policy established by the Kyoto Protocol in 1997 and are being implemented by most industrialized countries. They are experimented by Europe since 2005 for industrial facilities and since 2008 by industrialized countries under Kyoto. The development of carbon markets will likely continue beyond 2012, when the Kyoto Protocol expires. Their expansion will be largely determined by the future international climate policy to be negotiated in Copenhagen in December 2009 and by the commitment of the largest economies like the United States. The authors describe the emergence of carbon markets, their basic principles and the experience of Kyoto and European markets. Then, they deal with the expected developments beyond 2012

Comparison of the acute effects of Tulbaghia violacea William Henry ...

African Journals Online (AJOL)

Purpose: To assess the effect of the crude methanol leaf extracts of Tulbaghia violacea William Henry Harvey (Alliaceae) on blood pressure (BP) and heart rate in ageing normotensive Wistar Kyoto rats (WKY), and compare the results obtained with those for adult spontaneously hypertensive rats (SHR). Methods: T.

Past and Future of the Kyoto Protocol. Final report

International Nuclear Information System (INIS)

Wijen, F.; Zoeteman, K.

2004-01-01

The present report reflects findings from a study on the realization of and prospects for the Kyoto Protocol. The purpose of the study was (1) to obtain insights into the factors that enabled the realization of the Kyoto Protocol, in particular the interactions among major parties involved; (2) to assess the future opportunities and threats of the Kyoto Protocol, in particular against the backdrop of an increasingly globalised world. The study was conducted from February up to December 2003 by (a) reviewing the literature, especially publications on the negotiation history of the Kyoto process, the social interactions enabling the realization of the Protocol, analyses of strengths and weaknesses, and future climate regimes; (b) conducting a series of interviews with representatives from government, academia, non-governmental organisations, and business, who have been - directly or indirectly - involved in the Kyoto process; (c) internal discussions,brainstorming and analysing the Protocol's strengths and weaknesses, possible future scenarios (including policy options), and the management of a possible failure of the Kyoto Protocol. The present report reflects and integrates the different sources. The first section deals with the past and the present. It discusses how the Kyoto Protocol could be realized despite the divergent interests, reflects on its architecture, and analyses major strengths and weaknesses. In the second section, we present possible future scenarios. We explore how different combinations of domestic and international commitment provide possible realities that national government may face when crafting climate policy. The third section provides an in-depth analysis of the possible event that the Kyoto Protocol fails. We discuss its definition and policy implications. The final section is reserved for overall conclusions and policy recommendations

A comparative study of the effect of diet and soda carbonated drinks on the histology of the cerebellum of adult female albino Wistar rats.

Science.gov (United States)

Eluwa, M A; Inyangmme, I I; Akpantah, A O; Ekanem, T B; Ekong, M B; Asuquo, O R; Nwakanma, A A

2013-09-01

Carbonated drinks are widely consumed because of their taste and their ability to refresh and quench thirst. These carbonated drinks also exist in the form of diet drinks, for example Diet Coke®, Pepsi®, extra. A comparative effect of the diet and regular soda carbonated drinks on the histology of the cerebellum of female albino Wistar rats was investigated. Fifteen adult female Wistar rats weighing between 180-200 g were divided into 3 groups; designated as groups A, B and C, and each group consisted of five rats. Group A was the Control group and received distilled water, while groups B and C were the experimental groups. Group B was administered 50 ml of regular soda (RS), and group C was administered 50 ml of diet soda (DS) each per day for 21 days, and the rats were sacrificed on Day 22, and their cerebellums excised and preserved. Histological result of the sections of the cerebellum showed shrunken and degenerated Purkinje cells with hypertrophied dendrites, especially in the DS group, which was less in the RS group compared to the control group. These results suggest that diet soda has adverse effect on the cerebellum of adult female albino Wistar rats.

Hepatic expression of spermatogenic genes and their transiently remarkable downregulations in Wistar-Kyoto rats in response to lead-nitrate administration: strain-difference in the gene expression patterns.

Science.gov (United States)

Nemoto, Kiyomitsu; Ito, Sei; Yoshida, Chiaki; Miyata, Misaki; Kojima, Misaki; Degawa, Masakuni

2011-06-01

Administration of lead ion (Pb) to rats and mice affects hepatic functions such as the induction of hepatic cell proliferation and upregulation of cholesterol biosynthesis. To identify the genes for which expression changes in response to Pb-administration, we analyzed hepatic gene expression patterns in stroke-prone spontaneously hypertensive rat (SHRSP), its normotensive control, Wistar-Kyoto rat (WKY), and Spraque-Dawley (SD) rat strains, 3, 6, and 12 hr later after single i.v. injection of lead nitrate (LN) at a dose of 100 µmol using a DNA microarray technique. The data analysis demonstrated that the expression of a great number of genes was transiently and remarkably downregulated 3 hr after LN-injection, and then recovered to control levels only in LN-injected WKY. These normal hepatic expression levels in WKY and SHRSP were much higher than those in SD rats. Furthermore, most of these genes were ones thought to be expressed specifically in the spermatids and/or testes; i.e. genes encoding protamin 1, transition protein 1, and transition protein 2. These findings suggest that the regulation system common to expression of all of these genes could be a target site of Pb-toxic action, at least, in the liver of WKY, and that this system might be similar to the system essential for spermatogenesis, especially spermiogenesis, in the testis. In addition, it appears that clarifying the cause of the difference between the systems of WKY and SHRSP might aid in identifying the pathologic genes in SHRSP. Finally, it will be an important to clarify how the products of the genes related to spermatogenesis, including spermiogenesis, are functional in the livers of WKY and SHRSP.

Negative Effect of Zinc on Testes, Testosterone and Gonadotrophins Levels in Adult Male Wistar Rats

Directory of Open Access Journals (Sweden)

D Sohrabi

2012-05-01

Full Text Available

Background and Objectives

The toxic effects of zinc leading to sebaceous gland closure, skin eczema and blister have been previously demonstrated in other studies. The aim of this study is to determine the chronic effects of zinc chloride (ZnCl₂   on testicular tissues, testosterone and gonadotrophins in adult male Wistar rats.

Methods

Twenty four Adult male Wistar rats were divided in to two groups of study and control with each group consisting of 12 rats. Study group rats received 10 mg/kg interaperitoneal Zinc chloride in normal saline (N.S every other day for 30 days. Control group rats received N.S during this time. Blood sample for hormonal evaluation were collected from hearts of these rats. The rats were destroyed and their testes were removed and fixed in a 10% formaldehyde and glutaraldehyde solution.

Results

The results of this study showed a significant decrease in the level of LH and testosterone hormone among the rats in the study group compared to the control group with p< 0.001  and

p< 0.01 respectively. Study of fine structure of testicular cells and tissues in the study group rats  revealed swelling of mitochondria, increase in smooth endoplasmic reticulum vacuolization and lysosomic granules (Autophagic vacuoles in cytosol of their germinal cells.

Conclusion

Based on the results of this study consumption of large amount of compounds which contain zinc should be controlled and limited among men. There is a need for further studies to evaluate and determine the reversibility of most hormonal and physiological changes due to usage of zinc containing compounds.

The Kyoto mechanisms and technological innovation

DEFF Research Database (Denmark)

Lund, Henrik

2006-01-01

Climate change response, including the implementation of the Kyoto targets as the first step, calls for technological innovation of future sustainable energy systems. Based on the Danish case, this paper evaluates the type of technological change necessary. During a period of 30 years, Denmark...... countries. Consequently, the innovative technological development has changed. This paper evaluates the character of such change and makes preliminary recommendations for policies to encourage the use of the Kyoto Mechanisms as an acceleration of the necessary technological innovation....

Kyoto : implications for utility regulation

International Nuclear Information System (INIS)

Dunsky, P.

2003-01-01

The author provided a historical perspective of energy use and the role of carbon in the western hemisphere by displaying a series of graphs showing carbon intensity of energy, carbon emissions from energy, and the long path to green power. The 1990s represented a decade of progress. Almost three times as much wind capacity as nuclear capacity was added worldwide in 2001. The main challenge for the 21st century will be to bring under-developed countries into the fold while perpetuating the economic and human progress of the twentieth century. It was emphasized that environmental damage caused by utilities must be reversed. The contemporary context for the Kyoto Protocol was reviewed. Canada's commitment under the Kyoto Protocol is to reduce greenhouse gas emissions by 6 per cent below 1990 levels. The challenge for utility regulators to meet this commitment was examined. The costs are not entirely excessive. Some of the regulatory issues were discussed, namely revising a broad rate making framework, cost recovery and others. The Kyoto compliance plan was also reviewed with reference to internal options, external options, identification of regulatory barriers, and consideration of greenhouse gas credit markets. figs

Effects of ligature-induced periodontitis in pregnant Wistar rats Efeito da doença periodontal induzida por ligadura na prenhez de ratas Wistar

Directory of Open Access Journals (Sweden)

Mariane Ponzio de Azevedo Galvão

2003-03-01

Full Text Available The aim of this study was to evaluate the influence of ligature-induced periodontal disease in pregnant rats on their newborn's health parameters. Twenty-four female adult Wistar rats were divided into two groups: the control group (G1 and the group that was submitted to dental ligatures around second upper molars (G2. After the four week period of development of periodontitis, the female animals were mated with male adult Wistar rats. There were no differences in the body weight of females between the two groups during mating and pregnancy. No differences were observed among the groups in relation to the viable newborn index. However, there were differences in newborn birth weight, explained by the diverse size of the litters. In this study, ligature-induced periodontal disease did not promote changes during pregnancy that resulted in low birth weight in newborn Wistar rats.O objetivo do presente estudo foi avaliar a influência da periodontite induzida por ligadura em ratas prenhes sobre parâmetros de saúde geral de seus filhotes. Vinte e quatro ratas Wistar de idade adulta foram divididas em dois grupos: grupo controle (G1 e grupo experimental, que recebeu ligaduras ao redor dos segundos molares superiores (G2. Após o período de indução de periodontite (quatro semanas, as ratas foram colocadas para cruzamento com ratos Wistar machos, adultos. Não houve diferença no peso corporal das fêmeas durante os períodos de cruzamento e prenhez. Também não foram observadas diferenças entre os grupos quanto à taxa de recém-nascidos viáveis. No entanto, houve diferença quanto ao peso dos recém-nascidos, sendo tal diferença explicada pela variação no tamanho das ninhadas. No presente estudo, doença periodontal induzida por ligadura não promoveu mudanças durante a prenhez que resultassem em baixo peso ao nascer dos filhotes Wistar.

Differential effects of a selective dopamine D1-like receptor agonist on motor activity and c-fos expression in the frontal-striatal circuitry of SHR and Wistar-Kyoto rats

Directory of Open Access Journals (Sweden)

Diaz Heijtz Rochellys

2006-05-01

Full Text Available Abstract Background Molecular genetic studies suggest the dopamine D1 receptor (D1R may be implicated in attention-deficit/hyperactivity disorder (ADHD. As little is known about the potential motor role of D1R in ADHD, animal models may provide important insights into this issue. Methods We investigated the effects of a full and selective D1R agonist, SKF-81297 (0.3, 3 and 10 mg/kg, on motor behaviour and expression of the plasticity-associated gene, c-fos, in habituated young adult male Spontaneously Hypertensive Rats (SHR, the most commonly used animal model of ADHD, and Wistar-Kyoto (WKY; the strain from which SHR were derived. Results SHR rats were more behaviourally active than WKY rats after injection with vehicle. The 0.3 mg/kg dose of SKF-81297 increased motor behaviour (locomotion, sifting, rearing, and sniffing in both SHR and WKY rats. Total grooming was also stimulated, but only in WKY rats. The same dose increased c-fos mRNA expression in the piriform cortex of both strains. The 3 mg/kg dose increased sifting and sniffing in both strains. Locomotion was also stimulated towards the end of the testing period. The intermediate dose decreased total rearing in both strains, and produced a significant increase in c-fos mRNA in the striatum, nucleus accumbens, olfactory tuberculum, and in the cingulate, agranular insular and piriform cortices. The 10 mg/kg dose of SKF-81297 produced a biphasic effect on locomotion, which was characterized by an initial decrease followed by later stimulation. The latter stimulatory effect was more pronounced in SHR than in WKY rats when compared to their respective vehicle-injected groups. The 10 mg/kg dose also stimulated sifting and sniffing in both strains. Both the 3 and 10 mg/kg doses had no effect on total grooming. The 10 mg/kg dose induced significantly higher levels of c-fos mRNA expression in the nucleus accumbens and adjacent cortical regions (but not striatum of SHR when compared to WKY rats

Kyoto PLUS: Efficient global emission trade for an effective future climate policy; Kyoto PLUS: Effizienter globaler Emissionshandel fuer eine zukuenftig wirksame Weltklimapolitik

Energy Technology Data Exchange (ETDEWEB)

Wicke, L. [Inst. fuer Umwelt-Management (IfUM) an der ESCP-EAP, Technische Univ. Berlin (Germany)

2007-08-15

The majority of climate protection experts believe that the Kyoto Protocol in its present version provides a basis for preventing the climate change from taking on disastrous dimensions. In the meantime however a mainstream of opinion has developed which advocates the establishment of a functioning global climate protection system for the post-Kyoto phase. Kyoto Plus, a global climate certification system, is a concept developed by the author of three expert opinions for the state of Baden-Wuerttemberg which takes the principles of the Kyoto Protocol a step forward while striving to eliminate its weaknesses and which has matured sufficiently to be put into practice. Systems of this or a similar kind could enable Germany to make a decisive additional contribution to global climate protection, as the author stated at the BT Hearing on 23 May 2007.

Clean Development Mechanism: Core of Kyoto Mechanism

Energy Technology Data Exchange (ETDEWEB)

Lee, Myung Kyun [United Nations Environment Programme (Denmark)

2000-06-01

Kyoto protocol is a foundation for achieving an ultimate goal of UNFCCC, which is to stabilizing greenhouse gas concentration in the air. The clean development system is a core element for successful implementation of Kyoto protocol with other Kyoto mechanisms. While UNFCCC requires a new paradigm changing to sustainable development considering demand and future environment from the past supply-oriented resource consumption, the clean development system will be used as a means of successful establishment of a new paradigm in 21st century. As environmental problem is integrated with economic problem and each country is thriving for securing its own economic benefit in the issue of environmental conservation, Korea should do its best to have both of global environmental conservation and economic benefit for its own. 1 tab.

Setting the stage: Outcome from Kyoto

International Nuclear Information System (INIS)

Manning, D.

1998-01-01

The commitment of the upstream oil and gas industry to implement actions to help Canadians become more efficient in their use of energy was discussed. The goals of the Rio Framework convention revolved around achieving greenhouse gas emissions reductions in the least costly manner. The industrial sector responded to that challenge through voluntary efforts to reduce greenhouse gases. However, from an industry perspective, the VCR (voluntary challenge registry) performance was inconsistent. While the upstream oil and gas industry participated aggressively, other industrial sectors, particularly the transportation sector, failed to participate. Progress was too slow and too late. The Third Conference of the Parties in Kyoto, resulted in a binding commitment of between 20 and 25 per cent per annum reduction for Canada. Emissions trading among developed countries is also included in the Kyoto Protocols. The speaker considered the reduction commitment of 20 to 25 per cent for Canada unrealistic, and suggested that the Kyoto protocol may be flawed, if only because so many of the details have not been spelled out. The importance of the roles of the federal and provincial governments in enforcing their consultative processes was emphasized. In the view of this speaker and that of the Canadian Association of Petroleum Producers, the biggest disappointments coming out of Kyoto, was the failure to gain meaningful involvement from the developing world. A global effort to reduce emissions cannot be achieved without the participation of the developing countries

Croatia energy planning and Kyoto Protocol

International Nuclear Information System (INIS)

Duic, Neven; Juretic, Franjo; Zeljko, Mladen; Bogdan, Z.

2005-01-01

Croatia as an Annex I country of the UN Framework Convention on Climate Change and a country that has pledged in the Annex B of the Kyoto Protocol to reduce its GHG emissions by 5% will have to envisage a new energy strategy. Compared to the energy consumption collapse in some transitional countries, Croatia has passed through a relatively short-term reduction of GHG emissions since 1990 because of higher energy efficiency of its pretransition economy. It is expected that in case of baseline scenario, it will breach the Kyoto target in 2003. Several scenarios of power generation are compared from the point of view of GHG emissions. The cost-effective scenario expects a mixture of coal and gas fired power plants to be built to satisfy the new demand and to replace the old power plants that are being decommissioned. More Kyoto friendly scenario envisages forcing the compliance with the Protocol with measures only in power generation sector by the construction of mainly zero emission generating capacity in the future, while decommissioning the old plants as planned, and is compared to the others from the GHG emissions point of view. The conclusion is that by measures tackling only power generation, it will not be possible to keep GHG emission under the Kyoto target level. The case of including the emissions from Croatian owned power plants in former Yugoslavia is also discussed

Carbon Sequestered, Carbon Displaced and the Kyoto Context

International Nuclear Information System (INIS)

Marland, G.; Schlamadinger, B.

1999-01-01

The integrated system that embraces forest management, forest products, and land-use change impacts the global carbon cycle - and hence the net emission of the greenhouse gas carbon dioxide - in four fundamental ways. Carbon is stored in living and dead biomass, carbon is stored in wood products and landfills, forest products substitute in the market place for products made from other materials, and forest harvests can be used wholly or partially to displace fossil fuels in the energy sector. Implementation of the Kyoto Protocol to the United Nations Framework Convention on Climate Change would result in the creation of international markets for carbon dioxide emissions credits, but the current Kyoto text does not treat all carbon identically. We have developed a carbon accounting model, GORCAM, to examine a variety of scenarios for land management and the production of forest products. In this paper we explore, for two simple scenarios of forest management, the carbon flows that occur and how these might be accounted for under the Kyoto text. The Kyoto protocol raises questions about what activities can result in emissions credits, which carbon reservoirs will be counted, who will receive the credits, and how much credit will be available? The Kyoto Protocol would sometimes give credits for carbon sequestered, but it would always give credits when fossil-fuel carbon dioxide emissions are displaced

Zinc deficient diet consequences for pregnancy andoffsprings of Wistar rats

OpenAIRE

Solé, Dirceu; Rieckmann, Brigitte; Lippelt, Raquel Mattos Costa; Lippelt, Ronaldo Tadeu Tucci; Amâncio, Olga Maria Silverio; Queiroz, Suzana de Souza; Naspitz, Charles Kirov

1995-01-01

Adult female Wistar rats (90 days old; weight 180 to 220 grams) were submitted to different zinc deficient diets (Zn; severe = 2.6 ppm; mild = 9.0 ppm and normal diet = 81.6 ppm), during 6 weeks. After this time they were coupled with normal male Wistar rats. No differences regarding fecundity and sterility were observed between the groups. During pregnancy, part of the animals from severe and mild Zn deficient groups received the same diet and the others received normal diet. The animals fro...

Developing the Digital Kyoto Collection in Education and Research.

Science.gov (United States)

Hill, Mark Anthony

2018-04-16

The Kyoto embryo collection was begun in 1961 by Dr. Hideo Nishimura. The collection has been continuously developed and currently contains over 44,000 human normal and abnormal specimens. Beginning online in 1997, the internet provided an opportunity to make embryos from the collection widely available for research and educational purposes (http://tiny.cc/Embryo). These embryonic development resources have been continuously published and available from that time until today. Published in Japanese as an Atlas of Embryonic Development. Published online as the Kyoto Human Embryo Visualization Project (http://atlas.cac.med.kyoto-u.ac.jp) and also as the Human Embryo Atlas (http://tiny.cc/Human_Embryo_Atlas). Published now electronically as a digital eBook (http://tiny.cc/Kyoto_Collection_eBook). This new digital format allows incorporation of whole embryo and histology manipulable images, labels, and a linked glossary. New imaging modalities of magnetic resonance imaging (MRI) and episcopic fluorescence image capture (EFIC) can also be easily displayed as animations. For research, the collection specimens and histological sections have been extensively studied and published in several hundred papers, discussed here and elsewhere in this special edition. I will also describe how the Kyoto collection will now form a major partner of a new international embryology research group, the Digital Embryology Consortium (https://human-embryology.org). The digital Kyoto collection will be made available for remote researcher access, analysis, and comparison with other collections allowing new research and educational applications. This work was presented at the 40th Anniversary Commemoration Symposium of the Congenital Anomaly Research Center, Graduate School of Medicine, Kyoto University, Japan, November, 2015. Anat Rec, 2018. © 2018 Wiley Periodicals, Inc. © 2018 Wiley Periodicals, Inc.

Globalization, transportation and Kyoto; Globalisatie, transport en Kyoto

Energy Technology Data Exchange (ETDEWEB)

Rodenburg, C.A.; Ubbels, B. [Afdeling Ruimtelijke Economie, Vrije Universiteit, Amsterdam (Netherlands); Nijkamp, P. [Economische Faculteit, Vrije Universiteit, Amsterdam (Netherlands)

2000-12-08

Globalization of the economy will probably coincide with more transport, as a result of which the environmental burden will increase. Thus, the Kyoto standards will be difficult to realize. Based on four economic scenarios with different levels of globalization insight is gained into the possible consequences of future developments (economic development, investment, consumption, (regional) specializations, and trade up to 2020) in the transportation sector, focusing on the Netherlands. Those developments have been made concrete by means of the Worldscan model, developed by the Netherlands Bureau for Economic Policy Analysis (CPB). 8 refs.

Achilles tendon of wistar rats treated with laser therapy and eccentric exercise

OpenAIRE

Souza, Maria Verônica de; Silva, Carlos Henrique Osório; Silva, Micheline Ozana da; Costa, Marcela Bueno Martins da; Dornas, Raul Felipe; Borges, Andréa Pacheco Batista; Natali, Antônio José

2015-01-01

ABSTRACTIntroduction:Both laser therapy and eccentric exercises are used in tendon injuries. However, the association of these physiotherapeutic modalities is yet little investigated.Objective:To evaluate the effect of low-level laser therapy associated to eccentric exercise (downhill walking) on Achilles tendinopathy of Wistar rats.Method:Eighteen Achilles tendon from 15 adult male Wistar rats were used. Tendons were distributed in six groups (laser, eccentric exercise, laser and eccentric e...

histological alterations of the pancreas of wistar rats following ...

African Journals Online (AJOL)

bmjwa

snuff) on the histological features of the pancreas of adult wistar rats. .... tobacco harvesters. J. Am. Med. Assoc. 229: 1880-8. Guyton, A. C. and Hall, J. E., 1996. Textbook of Medical. Physiology, 9th. Ed. W. B. Saunders Company,. Philadelphia, pp.

Ocean fertilization, carbon credits and the Kyoto Protocol

Science.gov (United States)

Westley, M. B.; Gnanadesikan, A.

2008-12-01

Commercial interest in ocean fertilization as a carbon sequestration tool was excited by the December 1997 agreement of the Kyoto Protocol to the United Nations Convention on Climate Change. The Protocol commits industrialized countries to caps on net greenhouse gas emissions and allows for various flexible mechanisms to achieve these caps in the most economically efficient manner possible, including trade in carbon credits from projects that reduce emissions or enhance sinks. The carbon market was valued at 64 billion in 2007, with the bulk of the trading (50 billion) taking place in the highly regulated European Union Emission Trading Scheme, which deals primarily in emission allowances in the energy sector. A much smaller amount, worth $265 million, was traded in the largely unregulated "voluntary" market (Capoor and Ambrosi 2008). As the voluntary market grows, so do calls for its regulation, with several efforts underway to set rules and standards for the sale of voluntary carbon credits using the Kyoto Protocol as a starting point. Four US-based companies and an Australian company currently seek to develop ocean fertilization technologies for the generation of carbon credits. We review these plans through the lens of the Kyoto Protocol and its flexible mechanisms, and examine whether and how ocean fertilization could generate tradable carbon credits. We note that at present, ocean sinks are not included in the Kyoto Protocol, and that furthermore, the Kyoto Protocol only addresses sources and sinks of greenhouse gases within national boundaries, making open-ocean fertilization projects a jurisdictional challenge. We discuss the negotiating history behind the limited inclusion of land use, land use change and forestry in the Kyoto Protocol and the controversy and eventual compromise concerning methodologies for terrestrial carbon accounting. We conclude that current technologies for measuring and monitoring carbon sequestration following ocean fertilization

NAFTA's shadow hangs over Kyoto's implementation

International Nuclear Information System (INIS)

Hornsby, D.J.; Summerlee, A.J.S.; Woodside, K.B.

2007-01-01

The Canadian government recently stated that it will not meet its Kyoto targets by the end of the first period in 2012, and instead proposed a twofold solution to reduce greenhouse gas emissions. The solutions involve the development of a Clean Air Act that will seek a 50 per cent reduction in emissions by 2050; and, participation in negotiations to determine the next steps for the Kyoto Protocol, post-2012. It was noted that as a ratified member of the Kyoto Protocol, Canada is still legally obligated to achieve its reduction requirements. However, as a co-signatory of the North American Free-Trade Agreement (NAFTA), Canada may be impeded from introducing and maintaining GHG reducing initiative since there are elements of NAFTA which may be used to block efforts that are considered discriminatory to trade. Chapter 11 of NAFTA assigns rights to Canadian, American and Mexican private investors to promote investment, ensure equal treatment and protect their investments against discrimination by NAFTA governments other than their own. These rights may challenge independent action by member states to reduce environmental risks. The authors emphasized that in order to avoid the possibility of legal challenges through Chapter 11 of NAFTA, it is important for the Canadian government to address various aspects of the flexibility mechanisms in the Kyoto Protocol. Three of these mechanisms were designed to reduce the financial burden and technological capacity issues associated with mitigating GHG emissions. These include emissions trading system, clean development mechanism, and joint implementation. The authors presented some policy recommendations to avoid future conflict. 26 refs

Induced-hypercholesterolemia as a probable cause of alterations in ...

African Journals Online (AJOL)

Methods: The telemetry technique was used to investigate the cardiovascular dysfunctions in induced hypercholesterolemia in Wistar Kyoto (WKY) rats. Methods for this investigation include: inducing hypercholesterolemic condition in Wistar Kyoto rats through diet; measuring the blood cholesterol levels of the experimental ...

Kyoto University-National Taiwan University International Symposium "Social Cognitive Biology on Representation of Environment

OpenAIRE

Saiki, Jun

2016-01-01

Sponsored by Kyoto University, National Taiwan University; Cosponsored by Unit for Advanced Studies of the Human Mind, Kyoto University, Kokoro Research Center, Kyoto University, Supported by Supporting Program for InteRaction-based Initiative Team Studies (SPIRITS), Kyoto University

Taking advantage of the Kyoto mechanisms in the natural gas industry; Benefices des mecanismes de Kyoto pour l'industrie du gaz naturel

Energy Technology Data Exchange (ETDEWEB)

Janssen, J. [Institute for Economy and the environment at the University of St. Gallen, IWOe-HSG (Switzerland)

2000-07-01

The Kyoto Protocol has laid the basis of global markets for greenhouse gas emission reductions. By means of the Kyoto Mechanisms Joint Implementation, the Clean Development Mechanism and International Emissions Trading it will be possible to produce abroad and trade internationally the greenhouse gas emission reductions needed to satisfy cost-efficiently the respective demand of industrialized countries. The paper analyses options available in the natural gas sector for realizing Joint Implementation and Clean Development Mechanism projects. Furthermore, it examines strategies that might be economically viable for companies operating in the natural gas sector for taking advantage of the Kyoto Mechanisms. (author)

Estimating the size of the potential market for the Kyoto flexibility mechanisms

NARCIS (Netherlands)

Zhang, Zhong Xiang

1999-01-01

The Kyoto Protocol incorporates emissions trading, joint implementation and the clean development mechanism to help Annex I countries to meet their Kyoto targets at a lower overall cost. This paper aims to estimate the size of the potential market for all three flexibility mechanisms under the Kyoto

The marbles of Kyoto

International Nuclear Information System (INIS)

Jeucken, M.H.A.

2000-01-01

Reduction of greenhouse gases can result in considerable costs and benefits for businesses. Financial institutes (e.g. banking and assurance companies) can develop and provide financial products to support industry and businesses which have to meet environmental regulations as set in the Kyoto Protocol and national environmental regulations. 6 refs

Retroauricular Approach for Targeted Cochlear Therapy Experiments in Wistar Albino Rats

Directory of Open Access Journals (Sweden)

Selçuk Mülazımoğlu

2017-06-01

Full Text Available Background: As the idea of stem cell technology in the treatment of sensorial hearing loss has emerged over the past decades, the need for in vivo models for related experiments has become explicit. One of the most common experimental models for inner ear stem cell delivery experiments is the Wistar albino rat. Aims: To investigate the surgical anatomy of the temporal bone of the Wistar albino rat with respect to the dissection steps, operative techniques and potential pitfalls of surgery. Study Design: Animal experimentation. Methods: Adult Wistar albino rats were operated on via the retroauricular approach under an operation microscope. The anatomy of the temporal bone, the surgical route to the temporal bulla and the inner ear were investigated. Technical details of surgical steps, complications and potential pitfalls during the surgery were noted. Results: The study group consisted of 40 adult Wistar albino rats. The mean times to reach the bulla and to achieve cochleostomy were 4.3 (2-13 min and 7.5 min (3.5-22 min, respectively. The mean width of the facial nerve was 0.84 mm (0.42-1.25 mm. The stapedial artery lay nearly perpendicular to the course of the facial nerve (88-93 °C. There were three major complications: two large cochleostomies and one massive bleed from the stapedial artery. Conclusion: The facial nerve was the key anatomical landmark in locating the bulla. By retrograde tracing of the facial nerve, it was possible to find the bulla ventral (inferior to the main trunk. The facial nerve trunk was the upper limit when drilling the bulla. By dissecting the main trunk of the facial nerve and retracting cranially, a large drilling space could be achieved. Our results suggest that the retroauricular approach is an effective, feasible route for inner ear drug delivery experiments in Wistar albino rats

Down to earth in Kyoto?

International Nuclear Information System (INIS)

Gielen, A.; Bollen, J.

1997-01-01

The proposals of the European Union (EU) and the US government for the negotiations at the climatic change conference in Kyoto, Japan, December 1997, are compared. The EU-proposal appears to have more support, but the US-proposal is more effective

A 2004 view of the Kyoto Protocol

International Nuclear Information System (INIS)

Singer, F.

2004-01-01

It may not be a household word, but by now the Kyoto Protocol has become a well-known political slogan. It is either ''fundamentally flawed'' (George W. Bush) or it is essential for saving the climate and humanity (Al Gore). There seems to be no in between. The Kyoto Protocol is a treaty to limit (i.e., ration) the use of energy to satisfy the concerns of environmental groups and other believers in global warming catastrophes. This group includes not only certified kooks but also such notables as former Treasury Secretary Paul O'Neill and Sir David King, chief scientific adviser to Her Majesty's government who equates the threat of warming with that of international terrorism. But Kyoto is quite ineffective, that is, it cannot really affect climate or even change the composition of the atmosphere. It is costly. And it is probably also defunct. Where did this treaty come from? Why is it being adopted by some countries but not by others? And what is its likely future?

Slovenia and Kyoto Obligation

International Nuclear Information System (INIS)

Tirsek, A.; Jevsek, F.; Plavcak, V.-P.

1998-01-01

The paper gives the possibilities of emission reduction as an obligation from Kyoto Protocol. The Slovenia environmental and energy strategies are regulated to implement the agreement to reduce the emissions of greenhouse gases by 8% to the year 2012 as regard the basic year 1986 in energy, transportation, industrial and other sectors, especially focused on electric power sector. (author)

The characteristic of the building damage from historical large earthquakes in Kyoto

Science.gov (United States)

Nishiyama, Akihito

2016-04-01

The Kyoto city, which is located in the northern part of Kyoto basin in Japan, has a long history of >1,200 years since the city was initially constructed. The city has been a populated area with many buildings and the center of the politics, economy and culture in Japan for nearly 1,000 years. Some of these buildings are now subscribed as the world's cultural heritage. The Kyoto city has experienced six damaging large earthquakes during the historical period: i.e., in 976, 1185, 1449, 1596, 1662, and 1830. Among these, the last three earthquakes which caused severe damage in Kyoto occurred during the period in which the urban area had expanded. These earthquakes are considered to be inland earthquakes which occurred around the Kyoto basin. The damage distribution in Kyoto from historical large earthquakes is strongly controlled by ground condition and earthquakes resistance of buildings rather than distance from estimated source fault. Therefore, it is necessary to consider not only the strength of ground shaking but also the condition of building such as elapsed years since the construction or last repair in order to more accurately and reliably estimate seismic intensity distribution from historical earthquakes in Kyoto. The obtained seismic intensity map would be helpful for reducing and mitigating disaster from future large earthquakes.

Domo arigato Kyoto: Four key lessons from the Kyoto Protocol for a new agreement in Paris 2015. Climate Brief no. 35

International Nuclear Information System (INIS)

Morel, Romain; Shishlov, Igor; Bellassen, Valentin

2014-05-01

The results from the first commitment period of the Kyoto Protocol (KP) show that developed countries fulfilled their commitments through varied strategies. However, the Kyoto protocol did not manage to stabilize global GHG concentrations; furthermore its direct impact on domestic emissions reductions is unclear. Nevertheless, the KP has likely paved the way for a low-carbon transition by establishing international standards on emissions monitoring and on emission reductions projects. Yet, domestic policies - especially the EU ETS - are the main driver of emissions reductions and the principal catalyzers of private finance flows. A new, more effective, agreement would therefore need to expand its coverage, and take down the specter of 'internationally binding' emission reductions commitments in order to focus on MRV requirements. Similar to Kyoto, a Paris outcome could take the form of a framework agreement setting up requirements and mechanisms with subsequent implementing agreements expected by 2020. (authors)

Kyotos helte og skurke

DEFF Research Database (Denmark)

Svendsen, Gert Tinggaard

1998-01-01

USA blev på Kyoto-konferencen i december kritiseret af energi- og miljøminister Svend Auken for at ville tjene på et globalt CO2-marked. Men håndhæves dette effektivt af FN, kommer det alle til gode. Et globalt CO2-marked kan blive et banebrydende styringsmiddel, som kan løse globale miljøproblem...

Blockade of α2-adrenergic receptors in prelimbic cortex: impact on cocaine self-administration in adult spontaneously hypertensive rats following adolescent atomoxetine treatment.

Science.gov (United States)

Baskin, Britahny M; Nic Dhonnchadha, Bríd Á; Dwoskin, Linda P; Kantak, Kathleen M

2017-10-01

Research with the spontaneously hypertensive rat (SHR) model of attention deficit/hyperactivity disorder demonstrated that chronic methylphenidate treatment during adolescence increased cocaine self-administration established during adulthood under a progressive ratio (PR) schedule. Compared to vehicle, chronic atomoxetine treatment during adolescence failed to increase cocaine self-administration under a PR schedule in adult SHR. We determined if enhanced noradrenergic transmission at α2-adrenergic receptors within prefrontal cortex contributes to this neutral effect of adolescent atomoxetine treatment in adult SHR. Following treatment from postnatal days 28-55 with atomoxetine (0.3 mg/kg) or vehicle, adult male SHR and control rats from Wistar-Kyoto (WKY) and Wistar (WIS) strains were trained to self-administer 0.3 mg/kg cocaine. Self-administration performance was evaluated under a PR schedule of cocaine delivery following infusion of the α2-adrenergic receptor antagonist idazoxan (0 and 10-56 μg/side) directly into prelimbic cortex. Adult SHR attained higher PR break points and had greater numbers of active lever responses and infusions than WKY and WIS. Idazoxan dose-dependently increased PR break points and active lever responses in SHR following adolescent atomoxetine vs. vehicle treatment. Behavioral changes were negligible after idazoxan pretreatment in SHR following adolescent vehicle or in WKY and WIS following adolescent atomoxetine or vehicle. α2-Adrenergic receptor blockade in prelimbic cortex of SHR masked the expected neutral effect of adolescent atomoxetine on adult cocaine self-administration behavior. Moreover, greater efficacy of acute idazoxan challenge in adult SHR after adolescent atomoxetine relative to vehicle is consistent with the idea that chronic atomoxetine may downregulate presynaptic α2A-adrenergic autoreceptors in SHR.

Kosten en gevolgen bij de toepassing van de Kyoto Mechanismen

NARCIS (Netherlands)

Moor AOG de; Bollen JC; MNV

2001-01-01

Unrestricted use of the Kyoto Mechanisms yields substantial cost savings on the implementation of the Kyoto Protocol. Annex-I emission trading can cut compliance costs by more than a third while global trading can further reduce costs to a fraction of the amount without emission trading. In absolute

Klimadiplomatiets afveje i Kyoto-processen

DEFF Research Database (Denmark)

Czeskleba-Dupont, Rolf

2014-01-01

Operationaliseringen af de i 1992 i Rio indgåede forpligtelser i forhold til UNFCCC (FNs Rammekonventionom klimaforandringerne) blev siden COP3 i Kyoto under dominerende indflydelse af USAs forhandlere. Kritik af resultaterne kom allerede i 1998 fra den tyske regerings rådgivere i WGBU, men blev...

The Project Based Mechanisms of the Kyoto Protocol. Credible Instruments or Challenges to the Integrity of the Kyoto Protocol?

Energy Technology Data Exchange (ETDEWEB)

Takeuchi Waldegren, Linn

2006-03-15

The project based mechanisms of the Kyoto Protocol are innovative instruments which allow projects to earn credits for reducing greenhouse gas (GHG) emissions. The credits can in turn be used by countries to reach their emissions targets according to the Kyoto Protocol. The Project based mechanisms are known as the Clean Development Mechanism (CDM) and the Joint Implementation (JI). If the project based mechanisms are to be effective policy instruments they must ensure the integrity of the Kyoto Protocol, and their ability to promote and prove real emission reductions is critical. The environmental credibility of the project based mechanisms will also ensure their ability to promote cost effectiveness. Key concepts in this context are environmental and project additionality, and their role and value for the project based mechanisms are analyzed. Environmental additionality is established by comparing a project's emissions to a baseline. The baseline's credibility is thus vital. The concept of project additionality is somewhat controversial, but is nonetheless of equal importance. The case studies of CDM approved methodologies (AMs) and proposed projects suggest that there are credibility issues that need to be addressed if the project based mechanisms are to promote real emissions reductions.

Report: demonstrable progresses of the France according the Kyoto protocol; Rapport: progres demontrables de la France selon le protocole de Kyoto

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-06-15

This document constitutes the report of the France on the demonstrable progresses according the application of the 3 article of the Kyoto protocol. The first chapter is a description of the french climatic policy, as the second presents the tendencies and the projections concerning the greenhouse effect gases emissions. The chapter 3 details the policies effects and the measures ( energy, transport, industry and wastes). The last chapter is devoted to the respect of the other engagements articles 10 and 11 of the Kyoto protocol. (A.L.B.)

The costs and benefits of early action before Kyoto compliance

International Nuclear Information System (INIS)

Pan, Haoran; Regemorter, D. van

2004-01-01

Transaction costs have negative effects on emissions trading. Recent debates on the Kyoto Protocol have emphasized the potential threat of transaction costs to the implementation of emissions trading for the Protocol and consequently to the successful implementation of the Protocol. One way to suppress transaction costs is to use experience. In line with the EU Green Paper, we propose that an experimental early action before the Kyoto period could be helpful to reduce the transaction costs in emissions trading for the Kyoto compliance. However, because early action will incur additional costs, the final gain due to early action will be the cost-saving net of the costs of early action. This paper explores the relationship between the transaction costs in emissions trading and the early action effort to reduce transaction costs in the case of Kyoto Protocol. We find that in general early action can effectively offset transaction costs and thus are economically efficient. Only in the case of high transaction costs and constantly slow learning process, early action may become inefficient

Making it work: Kyoto, trade and politics : Executive summary

Energy Technology Data Exchange (ETDEWEB)

Urquhar, I.

2002-11-01

In this document, the author examines the constraints that would be placed on policy makers in the event of the implementation of the Kyoto Protocol, and how it would affect trade agreements and federalism in Canada. A description of the Protocol and the concessions (carbon sinks and international emissions trading) gained by Canada are presented at the beginning of the document. The author offers several conclusions that could disturb both proponents and opponents of the Kyoto Protocol. It is said that the implementation of Kyoto can take a route other than that of drastic domestic emissions reductions, and this position is explored in the second section. The author indicates that corporate competitiveness could be boosted by strict environmental regulations. A range of policies that could be adopted by Canada, as proposed by numerous organizations, are highlighted in the third section of the document. The point of the World Trade Organization and the constraints imposed are not necessarily preventing all types of actions. However, the author is of the opinion that the North America Free Trade Agreement represents a real threat to the implementation of the Kyoto Protocol. Finally, it is indicated that Canada requires a national electricity policy, where big hydro utilities and public investment have major roles to play.

The Kyoto conference: French perspective

International Nuclear Information System (INIS)

Orliange Philippe

1998-02-01

The present article approaches the problem of the climate change from a French perspective, describing the process that let the topic acquire importance in the national government level. Also, they stand out the difficulties generated in the negotiations of the Kyoto Protocol, because the opposing positions have United States and the European block

The Kyoto Protocol Is Cost-effective

Directory of Open Access Journals (Sweden)

Marino Gatto

2002-06-01

Full Text Available Despite recent advances, there is a high degree of uncertainty concerning the climate change that would result from increasing atmospheric greenhouse gas concentrations. Also, opponents of the Kyoto Protocol raised the key objection that reducing emissions would impose an unacceptable economic burden on businesses and consumers. Based on an analysis of alternative scenarios for electricity generation in Italy, we show that if the costs in terms of damage to human health, material goods, agriculture, and the environment caused by greenhouse gas emissions are included in the balance, the economic argument against Kyoto is untenable. Most importantly, the argument holds true even if we exclude global external costs (those due to global warming, and account for local external costs only (such as those due to acidic precipitation and lung diseases resulting from air pollution.

Submission to the British Columbia government on the Kyoto Protocol

International Nuclear Information System (INIS)

2002-09-01

The Business Council provided its comments concerning the Kyoto Protocol and climate change to the government of British Columbia, recommending that a clear position be established quickly on the matter. The adopted position should also be disseminated broadly to allow stake holders sufficient time to prepare for the upcoming meetings of the Joint Ministers and First Ministers. The federal government has announced that the decision on whether to ratify the Kyoto Protocol will be made before the end of 2002, and this decision will have numerous effects on the people of British Columbia, businesses, workers, and consumers alike. The Business Council of British Columbia believes that the unique interests of the province can best be protected by a proactive approach. Actions plans are being prepared by several of the other provinces and territories, who have already stated their position concerning the Kyoto Protocol. The long-term risks of climate change for British Columbia have not been determined nor have the elements of a provincial approach. The following elements should be included in British Columbia's position on the Kyoto Protocol, according to the Business Council of British Columbia: (1) a credible and cost-effective implementation plan that does not unduly burden the province and other jurisdictions must be developed before Canada decides to ratify the Protocol. British Columbia should go on the record stating it does not support the ratification of the Kyoto Protocol in its present form. (2) the province should advocate for a national approach to climate change that can be achieved within a reasonable time frame, reflects the long-term nature of the problem, and is in agreement with the economic development objectives of British Columbia, (3) a plan detailing how the province intends to deal with the growth of greenhouse gas emissions should supplement and support the position of the province on the Kyoto Protocol. Consumers and business should be engaged

Kyoto protocol and Nepal's energy sector

International Nuclear Information System (INIS)

Pokharel, Shaligram

2007-01-01

Nepal has recently ratified Kyoto Protocol, which considers justifiable use of resources to limit or reduce the emission of gases that contribute to green house gas inventory in the atmosphere. Nepal's per capita green gas (GHG) emission from energy use is insignificant. However, it is important for Nepal to adopt environmentally friendly energy options based on local resources like hydropower and biomass. Nepal can benefit from the provisions of clean development mechanism (CDM) under the Kyoto Protocol of the United Nations Framework Convention on Climate Change (UNFCC) or carbon funds being promoted by various organizations in order to obtain funding for new projects that reduce GHG emissions (ER). Funding can be generated through Carbon trading in international market as well. In this paper, the country's current contribution to GHG due to energy consumption is evaluated. Options for promoting more sustainable and environmentally friendly projects have also been discussed

Influence of outdoor advertisement colors on psychological evaluation of townscape in Kyoto

Science.gov (United States)

Onishi, Ayumi; Ishida, Taiichiro; Katsuya, Yoshiko

2002-06-01

Outdoor advertisements must be one of the major factors that affect our psychological impression for townscapes. They often conflict with propr color environments in cities particularly in historic cities like Kyoto. In this study we investigated how outdoor advertisements influenced our visual evaluation of townscapes in Kyoto. In recent years, a new regulation for outdoor advertisements came into operation in Kyoto and some of the advertisements have been replaced or removed gradually. We examined psychological evaluation for the townscapes before and after their changes. In the experiment, subjects evaluated 'visual harmony,' 'visual busyness,' 'visual comfort' and 'suitability to Kyoto' of townscapes projected on a screen. The results indicated that the evaluation of 'visual busyness' significantly decreased with the amount of the advertisements. The relations between the advertisements and the psychological evaluation of the townscape are discussed.

The Kyoto mechanisms and the diffusion of renewable energy technologies in the BRICS

International Nuclear Information System (INIS)

Bodas Freitas, Isabel Maria; Dantas, Eva; Iizuka, Michiko

2012-01-01

This paper examines whether the Kyoto mechanisms have stimulated the diffusion of renewable energy technologies in the BRICS, i.e. Brazil, Russian, India China and South Africa. We examine the patterns of diffusion of renewable energy technologies in the BRICS, the factors associated with their diffusion, and the incentives provided by the Kyoto mechanisms. Preliminary analysis suggests that the Kyoto mechanisms may be supporting the spread of existing technologies, regardless if such technologies are still closely tied to environmental un-sustainability, rather than the development and diffusion of more sustainable variants of renewable energy technologies. This raises questions about the incentives provided by the Kyoto mechanisms for the diffusion of cleaner variants of renewable energy technologies in the absence of indigenous technological efforts and capabilities in sustainable variants, and national policy initiatives to attract and build on Kyoto mechanism projects. We provide an empirical analysis using aggregated national data from the World Development Indicators, the International Energy Agency, the United Nations Framework Convention on Climate Change and secondary sources. - Highlights: ► The Kyoto mechanisms may be supporting the diffusion of existing technologies. ► They may not be supporting the diffusion of sustainable renewable energy technologies. ► In the absence of appropriate capabilities and policies further diffusion is limited.

The effects of sildenafil ciltrate on the lateral geniculate body of adult Wistar rats (Rattus norvegicus- A histological study

Directory of Open Access Journals (Sweden)

Andrew Osayame Eweka

2010-07-01

Full Text Available The histological effect of oral administration of sildenafil citrate (Viagra, commonly used as an aphrodisiac and for the treatment of erectile dysfunction on one of the visual relay centres namely the lateral geniculate body (LGB of adult Wistar rat was carefully studied. The rats of both sexes (n=24, average weight of 202g were randomly assigned into three treatment (n=18 and control (n=6 groups. The rats in the treatment groups ‘A’, ‘B’ and ‘C’ received respectively, 0.25mg/kg, 0.70mg/kg and 1.43mg/kg body weight of sildenafil citrate base dissolved in distilled water daily for 30 days, through orogastric feeding tube, while that of the control group D, received equal volume of distilled water daily during the period of the experiment. The rats were fed with growers’ mash obtained from Edo Feeds and Flour Mill Ltd, Ewu, Edo State, Nigeria and were given water liberally. The rats were sacrificed on day thirty-one of the experiment. The lateral geniculate body (LGB was carefully dissected out and quickly fixed in 10% formal saline for histological studies. The histological findings after H&E method indicated that the treated section of the lateral geniculate body (LGB showed some varying degree of reduced cellular population based on its sparse distribution, degenerative changes, cellular hypertrophy, and intercellular vacuolations appearing in the stroma. Varying dosage and long administration of sildenafil citrate may have some deleterious effects on the neurons of the intracranial visual relay centre and this may probably have some adverse effects on visual sensibilities by its deleterious effects on the cells of the lateral geniculate body (LGB of adult Wistar rats. It is therefore recommended that further studies aimed at corroborating these observations be carried out.

Locomotor activity and catecholamine receptor binding in adult normotensive and spontaneously hypertensive rats

International Nuclear Information System (INIS)

Hellstrand, K.; Engel, J.

1980-01-01

The binding of 3 H-WB 4101, an α 1 -adrenoceptor antagonist, the membranes of the cerebral cortex, the hypothalamus, and the lower brainstem was examined in adult spontaneously hypertensive (SH) rats and in normotensive Wistar Kyoto (WK) controls. The specific binding of 3 H-WB 4101 (0.33 nM) was significantly higher in homogenates from the cerebral cortex of SH rats as compared to WK rats. No differences were detected between SH and WK rats in the specific binding of 3 H-spiroperidol (0.25 nM), a dopamine receptor antagonist, to membranes from the corpus striatum and the limbic forebrain. The locomotor activity was significantly higher in SH rats as compared to WK controls, in all probability due to a lack of habituation to environmental change. It is suggested that the high reactivity of SH rats is related to a disfunction in the noradrenergic neurons in the central nervous system. (author)

Application of the Kyoto Mechanisms in Finland's climate policy. Report of the Finnish Committee on the Kyoto mechanisms

International Nuclear Information System (INIS)

2001-01-01

By the flexible mechanisms under the Kyoto Protocol are meant project-specific Joint Implementation, JI, intended for emissions reduction in the industrialised countries and the Clean Development Mechanism, CDM, designed for emissions reduction in the developing countries. Joint Implementation Projects can be found particularly in the economies-in-transition The flexible mechanisms under the Protocol also include Emissions Trading, ET, which States - and according to the view of several parties, enterprises, too - can conduct subject to rules to be later agreed upon in connection with emissions rights The international climate negotiations on the Kyoto Protocol and on drafting more detailed rules on the use of the mechanisms are still pending. In fact, the Working Group thinks that the uncertainties so far connected with the flexible mechanisms will lead to a situation in which the national climate policy must, at this stage, be primarily based on domestic reduction measures. Even if Finland were prepared to meet her climate policy obligations through domestic measures, there is, in the Working Group's opinion, skill reason to continue the preparations for the possibilities of using the Kyoto flexible mechanisms, too. The prime goal of the flexible mechanisms is an internationally cost-efficient climate policy, which creates the preconditions for the gradual tightening of emission limitations in a manner that will hinder economic and other societal activity as little as possible. Thus the flexible mechanisms can become more important during later commitment periods. According to model calculations, using the mechanisms would probably be inexpensive compared to the domestic emission reduction measures. It seems that the international markets for assigned amount units obtained through the use of the mechanisms would be big enough in view of the relatively limited immediate needs of the Finnish Climate Policy. The larger the group of countries and operators trading in

Is Kyoto Fatally Flawed? An Analysis with MacGEM

International Nuclear Information System (INIS)

Eyckmans, J.; Van Regemorter, D.; Van Steenberghe, V.

2002-06-01

In this paper we present some numerical simulations with the MacGEM model to evaluate the consequences of the recent Marrakesh agreements and the defection of the USA for the Kyoto Protocol. MacGEM is a global marginal abatement cost model for carbon emissions from fossil fuel use based on the GEM-E3-World general equilibrium. Nonparticipation of the USA causes the equilibrium carbon price in Annex B countries to fall by approximately 50% since an important share of permit demand falls out. Carbon sinks enhancement activities enable Parties to fulfil their reduction commitment at lower compliance costs and cause the equilibrium permit price to decrease by 40%. Finally, it is shown that the former Soviet Union and central European countries have substantial monopoly power in the Kyoto carbon permit market. We conclude that the recent accords have eroded completely the Kyoto Protocol's emission targets but that they have the merit to have saved the international climate change negotiation framework

Hydro in the Kyoto era

International Nuclear Information System (INIS)

Bourdon, M.-C.

2003-01-01

Quebec has the best performance in North America in terms of greenhouse gas (GHG) emissions. Unlike neighbouring provinces and states which rely heavily on coal for power generation, Quebec generates 96 per cent of its electricity from hydroelectric power. However, no new dams have been built in the past decade in Quebec due to land disputes with Aboriginal communities and general distrust among many ecologists. It takes about 12 years for a hydroelectric project to come to fruition. For that reason, and in order to capitalize on energy market opportunities, Hydro-Quebec is seriously considering expanding its generating capability beyond the needs of Quebec consumers, with gas-fired thermal generating stations. Environmental groups claim that the proposal to build the Suroit combined-cycle facility near the United States border destroys Quebec's efforts to honour the Kyoto Protocol. Economists argue that it is entirely in the spirit of Kyoto if exports of hydroelectricity or natural gas from Canada to the United States leads to less use of oil or coal. But one energy modeling expert at INRS-Energie et Materiaux claims that Quebec has a moral obligation to develop hydroelectricity for its own use as well as for export purposes, noting that any country with the good fortune to have renewable forms of energy, such as wind and hydro, should develop them to lower world GHG emissions. Quebec has many opportunities to sell hydroelectricity even while domestic demand grows. Hydroelectricity from Quebec should interest some states that have adopted their own GHG reduction standards, despite the U.S. government's refusal to ratify Kyoto. It should also interest Ontario and the Maritimes because they will be trying to reduce emissions from their thermal plants. The current situation does not favour the Kyoto Protocol. Exports of electricity from Quebec have dropped because no new dams have been built in recent years and gas-fired plants are looking more attractive to power

Effect of Ruta graveolens and Cannabis sativa alcoholic extract on spermatogenesis in the adult wistar male rats

Directory of Open Access Journals (Sweden)

M R Sailani

2007-01-01

Full Text Available Objective: The present study was undertaken to evaluate the effects of alcohol extracts of Ruta graveolens and Cannabis sativa that were used traditionally in medieval Persian medicine as male contraceptive drugs, on spermatogenesis in the adult male rats. Materials and Methods: Ethanol extracts of these plants were obtained by the maceration method. The male rats were injected intraperitionaly with C. sativa and R. graveolens 5% ethanol extracts at dose of 20 mg/day for 20 consecutive days, respectively. Twenty-four hours after the last treatment, testicular function was assessed by epididymal sperm count. Result: The statistical results showed that the ethanol extracts of these plants reduced the number of sperms significantly ( P =0.00 in the treatment groups in comparison to the control group. The results also showed that the group, treated by extract of R. graveolens reduced spermatogenesis more than the group treated by extracts of C. sativa . Conclusion: The present study demonstrated the spermatogenesis reducing properties of the ethanol extracts of R. graveolens and C. sativa in the adult male wistar rats but more studies are necessary to reveal the mechanism of action that is involved in spermatogenesis.

Hepatoprotective effects of Rauwolfia vomitoria extract on the liver of aduit wistar rats

Directory of Open Access Journals (Sweden)

Ezejindu D N

2013-12-01

Full Text Available This work focuses primarily on investigating hepatoprotective effects of Rauwolfia vomitoria extract on the liver of adult wistar rats following oral administration. Twenty wistar rats of weights 195 – 215kg were divided into four groups designated as A,B,C and D. Group  A served as the control and were orally administered with 0.4ml of distilled water daily; the experimental groups B,C & D were orally administered with 0.6ml, 0.75ml and 0.81ml of Rauwolfia vomitoria extract for twenty eight days. Twenty four hours after the last administration, the animals were weighed, anasthetized under chloroform vapour and dissected. Liver tissues were removed, weighed and trimmed down for histological studies. The final body weight of the experimental groups (B,C &D increased significantly(P<0.001 with the control. The relative liver weight of the experimental groups B,C &D statistically increased (P<0.001 with the control (A. Histological results showed normal liver architecture in the experimental groups B,C, & D relative to the control (A.  This study therefore suggest that consumption of Rauwolfia vomitoria extract at different doses did not induce hepatotoxicity in the liver of adult wistar rats.

Climate change ratification of the Kyoto Protocol : clearing the air on the debate

International Nuclear Information System (INIS)

2002-01-01

The Kyoto Protocol on Climate Change would commit Canada to limit emissions of greenhouse gases to 6 per cent below 1990 levels by 2008-2012. The Canadian Chamber of Commerce has outlined the following 3 key prerequisites that the federal government should and will have in place before any decision on ratification is made: (1) a detailed plan for achieving the Kyoto reductions, (2) a detailed analysis of environmental and economic impacts associated with Kyoto implementation, and (3) consultations with all stakeholder and the Canadian public once the plan has been released. Currently, Canadian businesses are taking voluntary actions to reduce industrial sector emissions through programs such as the Canadian Industry Program for Energy Conservation. Between 1990 and 1999, industrial sector emissions fell by 6 per cent. However, it was emphasized that despite these efforts, the gap between Canada's Kyoto target and its current greenhouse gas emissions continues to grow because of population and economic growth and rising exports. At the current rate of growth, it is estimated that meeting the Kyoto target could cost the economy up to $30 billion in 2010. The paper also discusses the implementation of key flexibility mechanisms such as carbon sinks, Joint Implementation, the Clean Development Mechanism and credits for export of cleaner energy to the United States, a non-Kyoto country. It is argued that ratification of Kyoto could hurt investments and impact jobs in Canada by making Canadian industries uncompetitive relative to their American counterparts. It is emphasized that full participation by the Canadian public is required in adapting to major lifestyle changes to reduce the use of fossil fuels and other sources of greenhouse gases. In conclusion, the Canadian Chamber of Commerce does not believe that the Kyoto Protocol is the most effective and efficient way of moving forward on the climate change issue and recommends that the federal government develop a made

The Kyoto Agreement: Trade and Design

DEFF Research Database (Denmark)

Svendsen, Gert Tinggaard

1999-01-01

The Kyoto Agreement from 1997 allows trade of CO2 emission quotas between the 38 industrialized countries which have committed themselves to an emission ceiling. However, it does not define how this potential trade system should be designed. The intention was to clarify these matters during the 1...

Estimating the size of the potential market for the Kyoto flexibility mechanisms

NARCIS (Netherlands)

Zhang, Z.X.

2000-01-01

The Kyoto Protocol incorporates three flexibility mechanisms to help Annex I countries to meet their Kyoto targets at a lower overall cost. This paper aims to estimate the size of the potential market for all three mechanisms over the first commitment period. Based on the national communications

Cost estimation of Kyoto Protocol

International Nuclear Information System (INIS)

Di Giulio, Enzo

2005-01-01

This article proposes a reflection on important aspects in the costs determination performance of Kyoto Protocol. The evaluation of the main models evidence possible impacts on the economies. A key role in the determination of the cost is represented by the relative hypothesis to emission trading and the projects CDM-JI and from the political capacity at the cost negative or equal to zero [it

Oral administration of leaf extracts of Momordica charantia affect reproductive hormones of adult female Wistar rats

Science.gov (United States)

Adewale, Osonuga Odusoga; Oduyemi, Osonuga Ifabunmi; Ayokunle, Osonuga

2014-01-01

Objective To determine the effect of graded doses of aqueous leaf extracts of Momordica charantia on fertility hormones of female albino rats. Methods Twenty adult, healthy, female Wistar rats were divided into four groups: low dose (LD), moderate dose (MD) and high dose (HD) groups which received 12.5 g, 25.0 g, 50.0 g of the leaf extract respectively and control group that was given with water ad libatum. Result Estrogen levels reduced by 6.40 nmol/L, 10.80 nmol/L and 28.00 nmol/L in the LD, MD and HD groups respectively while plasma progesterone of rats in the LD, MD and HD groups reduced by 24.20 nmol/L, 40.8 nmol/L and 59.20 nmol/L respectively. Conclusion Our study has shown that the antifertility effect of Momordica charantia is achieved in a dose dependent manner. Hence, cautious use of such medication should be advocated especially when managing couples for infertility. PMID:25183143

Association between the Frequency of Protein-Rich Food Intakes and Kihon-Checklist Frailty Indices in Older Japanese Adults: The Kyoto-Kameoka Study.

Science.gov (United States)

Yamaguchi, Miwa; Yamada, Yosuke; Nanri, Hinako; Nozawa, Yoshizu; Itoi, Aya; Yoshimura, Eiichi; Watanabe, Yuya; Yoshida, Tsukasa; Yokoyama, Keiichi; Goto, Chiho; Ishikawa-Takata, Kazuko; Kobayashi, Hisamine; Kimura, Misaka

2018-01-13

We aimed to investigate whether frequencies of protein-rich food intake were associated with frailty among older Japanese adults. A cross-sectional study was conducted in 2011 among 3843 men and 4331 women in a population-based cohort of Kameoka city, Kyoto Prefecture, Japan. Frailty was assessed by the weighted score based on the 25-item Kihon-Checklist. The frequency of protein-rich food intake was examined as "seafood", "meat", "dairy products", "eggs", and "soy products". The outcome of frailty was analyzed with a multiple logistic regression model using the frequency of protein-rich food intake. When compared to the first quartile, it was observed that there was a significant association between the lower adjusted prevalence ratio (PR) for frailty and the frequency of seafood intake in the fourth quartile among men (PR 0.64, 95% confidence interval (CI), 0.42, 0.99) and from the second quartile to the third quartile among women (PR 0.61, 95% CI, 0.43, 0.85; PR 0.64, 95% CI, 0.46, 0.91). The frequency of dairy products intake in the third quartile among women was significantly associated with a lower PR for frailty ( p -value = 0.013). Our findings suggest that the consumption of seafood and dairy products may help older adults in maintaining their independence.

Association between the Frequency of Protein-Rich Food Intakes and Kihon-Checklist Frailty Indices in Older Japanese Adults: The Kyoto-Kameoka Study

Directory of Open Access Journals (Sweden)

Miwa Yamaguchi

2018-01-01

Full Text Available We aimed to investigate whether frequencies of protein-rich food intake were associated with frailty among older Japanese adults. A cross-sectional study was conducted in 2011 among 3843 men and 4331 women in a population-based cohort of Kameoka city, Kyoto Prefecture, Japan. Frailty was assessed by the weighted score based on the 25-item Kihon-Checklist. The frequency of protein-rich food intake was examined as “seafood”, “meat”, “dairy products”, “eggs”, and “soy products”. The outcome of frailty was analyzed with a multiple logistic regression model using the frequency of protein-rich food intake. When compared to the first quartile, it was observed that there was a significant association between the lower adjusted prevalence ratio (PR for frailty and the frequency of seafood intake in the fourth quartile among men (PR 0.64, 95% confidence interval (CI, 0.42, 0.99 and from the second quartile to the third quartile among women (PR 0.61, 95% CI, 0.43, 0.85; PR 0.64, 95% CI, 0.46, 0.91. The frequency of dairy products intake in the third quartile among women was significantly associated with a lower PR for frailty (p-value = 0.013. Our findings suggest that the consumption of seafood and dairy products may help older adults in maintaining their independence.

Two roads to Kyoto: more or less

Energy Technology Data Exchange (ETDEWEB)

Stanford, J. [Canadian Auto Workers Union (Canada)

2003-01-01

According to this author, in implementing the Kyoto Protocol Canadians are faced with two alternatives: one is consuming less, driving less, and turning down the thermostat, the other is to follow the route of using energy more efficiently, which would allow us to continue to do what we like to do, including driving and staying warm in the winter. The author contends that the federal government's plan relies too heavily on moral suasion, guilt-tripping consumers into reducing their driving and reducing their GHG emissions by turning down their thermostats. The method more likely to succeed would be to encourage fuel-efficient technologies, providing incentives to promote the early commercial production in Canada of low-emission vehicles, along with tax incentives and mandatory market penetration targets. Sensible measures to push automakers to continue improving the average fuel efficiency of new vehicles, shaping and regulating the auto industry to speed up the development of hybrid fuel vehicles and other technological innovations such as continuously variable transmissions, variable valve control and direct injection technologies in engines would also advance the cause of energy efficiency. Regulations regarding motor vehicle recycling, other policies to promote steel recycling, incentives, including higher gasoline taxes, and measures which would mesh with a broader strategy to help Canadians to meet their own Kyoto challenges, are also badly needed. The right decisions on these matters will determine whether ratifying the Kyoto Protocol will be beneficial or detrimental to the Canadian economy.

Kyoto protocol: at last the agreement has been reached; Protocole de Kyoto: un accord enfin conclu

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-07-01

After more than 3 years of negotiations, 180 countries agreed at Bonn on the application of the Kyoto protocol to fight the climatic warming. The main aspects of this agreement are discussed: the carbon wells, the tools of the pollution control for the developed countries and the financial help to the developing countries. (A.L.B.)

Investigation of liver tissue and biochemical parameters of adult wistar rats treated with Arctium lappa L.

Directory of Open Access Journals (Sweden)

Fabrícia Souza Predes

2009-04-01

Full Text Available This study was carried out to evaluate the effects of Arctium lappa L. (burdock on the liver of adult male Wistar rats as measured by light microscopy and biochemical parameters. The rats received the extract in water bottles at doses of 10 or 20 g/L daily for 40 days. There were no significant changes in the plasma levels of albumin, aspartate transaminase (AST, alanine transaminase (ALT, gamma glutamyl transferase (GGT, total protein, total cholesterol, urea, uric acid, triacylglycerol, calcium, phosphorus, chlorine and direct bilirubin. The morphological analysis did not reveal histopathological alterations in liver tissue. Both biochemical and morphological data did not indicate A. lappa toxicity.A bardana (Arctium lappa L é uma planta trazida do Japão e aclimatada no Brasil, e é extensamente utilizada na medicina popular em todo mundo. Este estudo foi realizado para avaliar os possíveis efeitos da A. lappa no fígado e nos parâmetros bioquímicos plasmáticos em ratos Wistar adultos. Estes receberam a infusão de bardana nas doses de 10 ou 20 g de folhas secas /L de água, por 40 dias. Não houve alteração significativa nos níveis plasmáticos de albumina, aspartato transaminase (AST, alanina transaminase (ALT, gamma glutamil transferase (GGT, proteínas totais, colesterol total, uréia, ácido úrico, triglicérides, cálcio, fósforo, bilirrubina direta e cloro. A análise morfológica não revelou alterações histopatológicas no fígado. Os dados bioquímicos e morfológicos não indicaram a toxicidade da bardana.

The Kyoto Protocol. An economic appraisal

International Nuclear Information System (INIS)

Grubb, M.

2000-05-01

This paper examines the overall economics of the Kyoto Protocol on climate change, in three main parts. The first part explores the structure of the Protocol and how this matches against classical economic criteria of an 'optimal' climate change agreement. This discussion also considers the nature of and reasons for shortcomings, and the prospects for its evolution. Given the various flexibilities in the agreement, the Kyoto Protocol is far more economically efficient in its structure than any previous global environmental agreement. The central conclusion is that, from an economic perspective, the Protocol's structure for industrialised country commitments is as good as could reasonably be expected. The second part of the paper explores more closely the economics of the commitments themselves and how they combine with the various flexibilities, briefly reviewing the available literature and using a simple spreadsheet model of how the commitments might combine with trading mechanisms under a range of assumptions. Flexibility is intrinsic and necessary, but it is argued that the allocations to Russia and Ukraine in particular mean that unlimited flexibility could render the Protocol's commitments weaker in their impacts than is economically desirable to address climate change. It is argued that, should this prove to be the case, access to the large surplus in the transition economies could be used as a control valve to limit the costs of the Protocol to within acceptable limits. Finally, the paper considers the issues of developing country involvement in the Kyoto Protocol, and the Protocol's longer-term impact and evolution, including its impact on technological evolution and dissemination and the evolution of future commitments. It is argued that taking account of such issues critically affects views of the Protocol

The Kyoto University tandem upgrading project

International Nuclear Information System (INIS)

Nakamura, Masanobu; Shimoura, Susumu; Takimoto, Kiyohiko; Sakaguchi, Harutaka; Kobayashi, Shinsaku

1988-01-01

A brief description on the Kyoto University tandem upgrading project. The project consists of replacing the old 5 MV tandem Van de Graaff by an 8UDH pelletron. The old pressure vessel and beam lines are used again without significant modification. The project is planned to be completed at the end of 1989. (orig.)

Fossil fuels: Kyoto initiatives and opportunities. Part 1

International Nuclear Information System (INIS)

Pinelli, G.; Zerlia, T.

2008-01-01

GHG emission in the upstream step of fossil fuel chains could give an environmental as well as economic opportunity for traditional sectors. This study deepens the matter showing an increasing number of initiative over the last few years taken both the involved sectors and by various stake holders (public and private subjects) within the Kyoto flexible mechanism (CDM and JI) or linked to voluntary national or at a global level actions. The above undertakings give evidence for an increased interest and an actual activity dealing with GHG reduction whose results play an evident and positive role for the environment too. Part 1. of this study deals with fossil fuel actions within the Kyoto protocol mechanism. Part 2. will show international and national voluntary initiative [it

Exploring the ancillary benefits of the Kyoto Protocol for air pollution in Europe

International Nuclear Information System (INIS)

Vuuren, D.P. van; Cofala, J.; Eerens, H.E.; Oostenrijk, R.; Heyes, C.; Klimont, Z.; Elzen, M.G.J. den; Amann, M.

2006-01-01

An integrated approach to climate change and regional air pollution can harvest considerable ancillary benefits in terms of environmental impacts and costs. This is because both problems are caused to a large extent by the same activity (fossil fuel combustion). Substantial ancillary benefits were found for regional air pollution (SO 2 , NO x , VOC and particulate matter) of implementing the Kyoto Protocol (intended to control greenhouse gas emissions) in Europe. For instance, while three different scenarios on Kyoto implementation were found to reduce European CO 2 emissions by 4-7%, they also reduced European emissions of SO 2 by 5-14% compared with a no Kyoto policies case. The magnitude of ancillary benefits depends on how flexible mechanisms and surplus emission allowances are used in meeting the Kyoto targets. The total cost savings for implementing current policies for regional air pollution of the Kyoto Protocol are of an order of 2.5-7 billion Euro. In all cases, this is in the order of half the costs of the climate policy (4-12 billion Euro). Using flexible mechanisms reduces emissions of air pollutants for Europe as a whole even further than domestic implementation (e.g. 10-14% versus 5% for SO 2 emissions), but the reductions are shifted from Western Europe to Central and Eastern Europe and Russia. The use of surplus emission allowances to achieve the Kyoto targets decreases the ancillary benefits, in particular for the latter group of countries (e.g. unprotected area against acidification increases from 1.3 to 1.7 million ha)

Report: demonstrable progresses of the France according the Kyoto protocol

International Nuclear Information System (INIS)

2006-06-01

This document constitutes the report of the France on the demonstrable progresses according the application of the 3 article of the Kyoto protocol. The first chapter is a description of the french climatic policy, as the second presents the tendencies and the projections concerning the greenhouse effect gases emissions. The chapter 3 details the policies effects and the measures ( energy, transport, industry and wastes). The last chapter is devoted to the respect of the other engagements articles 10 and 11 of the Kyoto protocol. (A.L.B.)

Science Hall of Atomic Energy in Research Reactor Institute, Kyoto University

International Nuclear Information System (INIS)

Hayashi, Takeo

1979-01-01

The Science Hall of Atomic Energy was built as a subsidiary facility of the Research Reactor Institute, Kyoto University. The purpose of this facility is to accept outside demands concerning the application of the research reactor. The building is a two story building, and has the floor area of 901.47 m 2 . There are an exhibition room, a library, and a big lecture room. In the exhibition room, models of the Kyoto University Research Reactor and the Kyoto University Critical Assembly are placed. Various pictures concerning the application of the reactor are on the wall. In the library, people from outside of the Institute can use various books on science. Books for boys and girls are also stocked and used for public use. At the lecture room, various kinds of meeting can be held. (Kato, T.)

The Kyoto protocol becomes effective - implications for french forests

International Nuclear Information System (INIS)

Chaudron, Alain; Morel, Michel-Paul; Merckx, Valerie; Gaborit, Guillaume

2005-01-01

The Kyoto Protocol came into force on February 16, 2005. The article takes stock of ongoing processes and their consequences for French forests. It first describes the Kyoto Protocol and the framework agreement on climate change from which it is derived, then the particular implementing regulations for forestry stakeholders and the detailed rules for applying it to French forests, and specifically the complex accounting rules that arose from negotiations, and finally the future outlook of these processes that have been regularly revised at annual meetings and will continue to be developed. Indeed, the international dialogue concerning the post-2012 era has already begun. (authors)

the central europe and the Kyoto protocol on the climatic changes

International Nuclear Information System (INIS)

Mariotte, C.

2006-01-01

This book presents little known aspects of the Kyoto protocol concerning the Central Europe or Visegrad Group and analyzes the environmental problem in a context of political transitions. The impacts of the Kyoto protocol and more especially the pollution permits market, on these countries are presented. It precises the shadow zones, the hope and the great willingness which qualify this great project and which are poorly discussed by the economists. (A.L.B.)

Protocolos de Montreal e Kyoto: pontos em comum e diferenças fundamentais Montreal and Kyoto Protocols: common points and essential differences

Directory of Open Access Journals (Sweden)

Darly Henriques da Silva

2009-12-01

Full Text Available Os Protocolos de Montreal e Kyoto, tratados internacionais de defesa do meio ambiente e da vida, controlam gases que provocam o buraco na camada de ozônio e o efeito estufa, respectivamente, resultantes de atividades industriais e uso da terra. O artigo enfatiza pontos comuns e diferenças entre eles, fornecendo atualização dos protocolos.Montreal and Kyoto Protocols, international treaties, aim at safeguarding the environment and life by controlling the use of gases which deplete the ozone layer and cause the greenhouse effect, respectively, due to industrial and land use activities. The article highlights common points and differences and provides an update discussion about the protocols.

Kyoto protocol and its implementation in pakistan: hurdles and expectations

International Nuclear Information System (INIS)

Iqbal, S.; Sher, H.A.; Qureshi, S.A

2010-01-01

In 1997 Kyoto protocol was adopted at the third session of Conference of the parties of UNFCC in Kyoto, Japan. This protocol restricts the industrialized countries and those in transition to a market economy agreed to limit or reduce their emissions. In Pakistan the government is also taking steps to reduce the pollution. This paper discusses the possible low carbon emitting electricity generation options by keeping in view the current energy scenario of Pakistan and the new energy policy announced by the Government of Pakistan for renewable energy promotion. (author)

Climate policy after Kyoto

International Nuclear Information System (INIS)

Gerholm, T.R.

2002-01-01

The Kyoto Convention recommends reductions in emissions of CO 2 and other greenhouse gases, to mitigate the rate of climate change. Lively debate has taken place in many countries, not least over the political and economic implications. The basis for the Kyoto discussions was a set of studies commissioned, compiled and published by the UN's International Panel on Climate Change (IPCC). At first glance this scientific foundation plainly shows that significant climate change will occur unless emissions of greenhouse gases are sharply curtailed. On closer examination, the scientific evidence provided in the IPCC material is far from clear. Reputable scientists have expressed critical views about the interpretation of the scientific results and, even more, of the way the material is being used for policy purposes. The main purpose of this book is to voice this critique. To give the reader some context, a central section from the IPCC's basic document is presented first. There follow nine papers, by prominent natural and social scientists, in which the reasons for their sceptical attitudes are developed. A final paper by Professor Bert Bolin, chairman of the IPCC during the time when most of the material was produced, provides a response and commentary to the critique. The aim of the editor and authors, in presenting the material in this way, rather than as a polemical tract, is to leave open to the reader the question: Is global warming a consequence of man's activities, or are there other reasons; if so, is adopting policies with significant economic consequences, a reasonable response? (Author)

Reading the Kyoto Protocol. Ethical aspects of the convention on climate change

International Nuclear Information System (INIS)

Vermeersch, E.; Weiler, R.; Petrella, R.; Krause, F.; Sachs, W.; Zwart, H.; Keulartz, J.

2005-01-01

The Kyoto Protocol to the United Nations Framework Convention on Climate Change aims to reduce greenhouse gas emissions by urging the international community to take measures preventing 'dangerous man-made interference with the climate system'. Since its publication in 1997, the Kyoto Protocol has triggered heated debates among scientists and politicians. According to a number of critics, the questions as to whether global warming is caused by human intervention, and whether taking appropriate measures could reduce the trend, has not yet been conclusively answered. In a limited number of countries, this situation has led to a delay in the ratification process. Only when these disputes were settled in February 2005 the Kyoto Protocol became legally binding on all the signatories. If predictions are accurate, measures have to be taken to prevent a global catastrophe. This leads to another, much overlooked, but no less important question, namely how mankind can be motivated to accept the burden attached to the measures proposed by the Kyoto Protocol; in other words, how do we find and formulate an ethical basis for measures forcing us to sacrifice some of our wealth and riches, for a cleaner, more sustainable world?

Polarized ionic source of the tandem accelerator in Kyoto University

Energy Technology Data Exchange (ETDEWEB)

Nakamura, Masanobu; Kuwamoto, Shuichi; Takahashi, Seiji [Kyoto Univ. (Japan). Dept. of Physics] [and others

1997-02-01

A polarized ion source developed under the National Laboratory of High Energy Physics was transferred to the tandem accelerator in Kyoto University at beginning of 1993 to constitute a displacement of incidence into the accelerator. This was an atomic beam type polarized ion source, which is designed to adopt permanent magnets for 6 poles magnet to polarize the electron, to take out atomic nucleus on a shape of positive ion by ECR ionizer after transferring its polarization through transition using radio frequency (RFT), to make it negative ion by charge conversion using alkaline metal vapor, and to put it into the tandem accelerator. Test of the positive ion was finished at the National Laboratory of High Energy Physics, and test in Kyoto University was required after its negative ionization. As the estimated cost was unsufficient and entrance into the ion source facility in the tandem accelerator building was limited in Kyoto University, step of development was slow. Here is reported on present state of the ion source which is now operating stably. (G.K.)

Kyoto Protocol Objectives in Croatia Energy Planning: Nuclear Scenario

International Nuclear Information System (INIS)

Duic, N.; Bogdan, Z.; Juretic, F.; Zeljko, M.

2002-01-01

Croatia as an Annex I country of the United Nations Framework Convention on Climate Change (UNFCCC) and a country that has pledged in the Annex B of the Kyoto Protocol to reduce its greenhouse gases (GHG) emissions by 5% from the pre-transition level by the budget period 2008-12, will have to envisage a new energy strategy. Compared to the energy consumption collapse in some transitional countries like Russia and Ukraine, Croatia has passed through a relatively limited long term reduction of GHG emissions since 1990 because of higher efficiency of its pre-transition economy. It is expected that in case of business as usual scenario it will breach the Kyoto target in 2003 since the demand for energy will be high, especially as the income continues to rise, particularly in domestic use for heating, for transport and for electricity generation. Several scenarios of developing energy system are compared from the point of view of GHG emissions. The energy sector that will most probably be the most influenced by the UNFCCC objectives is electricity generation. Several scenarios are compared. The cost-effective scenario expects a mixture of coal and gas fired power plants to be built to satisfy the new demand and to replace the old power plants that are being decommissioned. More Kyoto friendly scenario envisages the construction of mostly nuclear power plants in the future, while decommissioning the old ones as planned, and is compared to the others from the GHG emissions point of view. The conclusion is that by measures tackling only electricity generation it will not be possible to keep GHG emission under the Kyoto target level, but that choosing the nuclear option might reduce significantly the cost of compliance. (author)

Remote Sensing and the Kyoto Protocol: A Workshop Summary

Science.gov (United States)

Rosenqvist, Ake; Imhoff, Marc; Milne, Anthony; Dobson, Craig

2000-01-01

The Kyoto Protocol to the United Nations Framework Convention on Climate Change contains quantified, legally binding commitments to limit or reduce greenhouse gas emissions to 1990 levels and allows carbon emissions to be balanced by carbon sinks represented by vegetation. The issue of using vegetation cover as an emission offset raises a debate about the adequacy of current remote sensing systems and data archives to both assess carbon stocks/sinks at 1990 levels, and monitor the current and future global status of those stocks. These concerns and the potential ratification of the Protocol among participating countries is stimulating policy debates and underscoring a need for the exchange of information between the international legal community and the remote sensing community. On October 20-22 1999, two working groups of the International Society for Photogrammetry and Remote Sensing (ISPRS) joined with the University of Michigan (Michigan, USA) to convene discussions on how remote sensing technology could contribute to the information requirements raised by implementation of, and compliance with, the Kyoto Protocol. The meeting originated as a joint effort between the Global Monitoring Working Group and the Radar Applications Working Group in Commission VII of the ISPRS, co-sponsored by the University of Michigan. Tile meeting was attended by representatives from national government agencies and international organizations and academic institutions. Some of the key themes addressed were: (1) legal aspects of transnational remote sensing in the context of the Kyoto Protocol; (2) a review of the current and future and remote sensing technologies that could be applied to the Kyoto Protocol; (3) identification of areas where additional research is needed in order to advance and align remote sensing technology with the requirements and expectations of the Protocol; and 94) the bureaucratic and research management approaches needed to align the remote sensing

Non-Kyoto radiative forcing in long-run greenhouse gas emissions and climate change scenarios

NARCIS (Netherlands)

Rose, S.K.; Kriegler, E.; Bibas, R.; Calvin, K.; Popp, A.; van Vuuren, D.P.|info:eu-repo/dai/nl/11522016X; Weyant, J.

2014-01-01

Climate policies must consider radiative forcing from Kyoto greenhouse gases, as well as other forcing constituents, such as aerosols and tropospheric ozone that result from air pollutants. Non-Kyoto forcing constituents contribute negative, as well as positive forcing, and overall increases in

Climate Change And The Kyoto Protocol

International Nuclear Information System (INIS)

Comsan, M.N.H.

2007-01-01

The problem of global warming is addressed. Changes in earth surface temperature, emission of CO 2 and other four major green house gases are presented. Effect of global warming on weather, ocean, and ecosystem is discussed. A brief history of the Kyoto protocol starting from the 151 Earth Summit in 1972 is outlined. An overview of the protocol and a brief summary are given

Analyzing the economic cost of the Kyoto protocol

International Nuclear Information System (INIS)

Khanna, N.

2001-01-01

This paper examines the cost of meeting the Kyoto Protocol commitments under alternative assumptions regarding technology and technical change. Real GDP is modeled as a function of the capital, labor, and energy inputs. The analysis is based on data for 23 Annex 1 countries from 1965 to 1999. Two important results emerge. First, the standard assumption of Hicks neutral technical change and time and scale independent output elasticities is not supported by the data. Second, when technical change is allowed to be biased in favor of the energy and capital inputs, and when the output elasticities vary with the level of factor use and over time, the loss in real GDP due to the Kyoto commitments rises substantially. On average, the loss in real GDP is one and a half times higher than obtained under the standard assumptions. 26 refs

Emission Trading and the Kyoto protocol: Are they efficient economic instruments?

International Nuclear Information System (INIS)

Ibanez Londono, Ana Maria

1998-02-01

The Kyoto Protocol establishes a tradeable permits market for green house gases -GHG- emissions to reduce the costs of meeting the Protocol obligations. Economic theory provides the arguments to support the creation of GHG tradeable permits. Several economic researches have shown that vis-a-vis command and control regulations, tradeable permits induce economic agents to achieve environmental goals at a minimum cost. However, the conditions to minimize costs through tradeable permits are stringent. Tradeable permits require well functioning markets, e.g. perfect competition and perfect information. The tradeable permits market created by the Kyoto Protocol hardly meet these necessary conditions. Some countries like Japan, Great Britain and the United Stated are large emitters and thus may exert market power. Price manipulation may have implications over the static and dynamic efficiency of the permits. This paper takes a first look to the consequences of imperfect markets on the tradeable permit system of the Kyoto Protocol

Kyoto global consensus report on Helicobacter pylori gastritis

NARCIS (Netherlands)

K. Sugano (Kentaro); J. Tack (Jan); E.J. Kuipers (Ernst); D.Y. Graham (David Y.); E. El-Omar; S. Miura (Soichiro); K. Haruma (Ken); M. Asaka (Masahiro); N. Uemura (Naomi); P. Malfertheiner

2015-01-01

textabstractObjective To present results of the Kyoto Global Consensus Meeting, which was convened to develop global consensus on (1) classification of chronic gastritis and duodenitis, (2) clinical distinction of dyspepsia caused by Helicobacter pylori from functional dyspepsia, (3) appropriate

Bali: an agreement in principle for post-Kyoto negotiations but no emissions reduction targets - Panorama 2008; Bali: un accord de principe pour des negociations post-Kyoto mais pas d'objectif de reduction - Panorama 2008

Energy Technology Data Exchange (ETDEWEB)

NONE

2008-07-01

Ten years have passed since December 1997, when the United Nations Framework Convention on Climate Change (UNFCCC) was signed in Kyoto. It's been a decade of tough international negotiations, leading to the beginnings of an international CO{sub 2} emissions trading market, whose future past 2012 remains uncertain. The December negotiations in Bali may not have produced a successor to the Kyoto Protocol, but they did get all parties to the Convention to sign an agreement in principle to post- Kyoto negotiations.

As if Kyoto mattered: The clean development mechanism and transportation

International Nuclear Information System (INIS)

Christopher Zegras, P.

2007-01-01

Transportation is a major source of greenhouse gas (GHG) emissions and the most rapidly growing anthropogenic source. In the future, the developing world will account for the largest share of transport GHG increases. Four basic components drive transportation energy consumption and GHG emissions: activities (A), mode share (S), fuel intensity (I) and fuel choice (F) (ASIF). Currently, the Kyoto Protocol's clean development mechanism (CDM) serves as the main international market-based tool designed to reduce GHG emissions from the developing world. Theoretically, the CDM has the dual purpose of helping developing countries achieve 'sustainable development' goals and industrialized countries meet their Kyoto emissions reduction commitments. This paper reviews overall CDM activities and transportation CDM activities to date and then presents findings from three case studies of transportation CDM possibilities examined with the ASIF framework in Santiago de Chile. The analysis suggests that bus technology switch (I) provides a fairly good project fit for the CDM, while options aimed at inducing mode share (S) to bicycle, or modifying travel demand via land use changes (ASI) face considerable challenges. The implications of the findings for the CDM and the 'post-Kyoto' world are discussed

Efeito do uso de pentoxifilina no período neonatal sobre a produção espermática em ratos Wistar adultos Effect of pentoxifylline during neonatal period on spermatic production in adult Wistar rats

Directory of Open Access Journals (Sweden)

T.A.P. Moraes

2009-02-01

Full Text Available Utilizaram-se doses crescentes de pentoxifilina em ratos Wistar neonatos visando aumentar a produção espermática em animais adultos. Trinta e sete animais foram distribuídos de acordo com os tratamentos: não tratados (n=10 e tratados com 1mg/kg (n=10, 5mg/kg (n=9 e 10mg/kg (n=8 de pentoxifilina (IP. Aos 90 dias, os animais foram anestesiados e perfundidos intracardiacamente com solução fixadora. Os testículos foram processados rotineiramente para inclusão em resina plástica à base de glicol metacrilato. Cortes histológicos de 4µm de espessura foram corados em azul de toluidina/borato de sódio a 1% e analisados histometricamente. O número de células de Sertoli por secção transversal diminuiu nos grupos tratados com 5mg/kg e 10mg/kg em relação aos grupos controle e tratado com 1mg/kg. O índice de células de Sertoli aumentou nos animais tratados com 5mg/kg em comparação aos do grupo-controle. A utilização da pentoxifilina não foi capaz de induzir aumento na população das células de Sertoli e produção espermática em ratos adultos.Increasing doses of pentoxifylline were administrated to newborn Wistar rats in order to augment Sertoli cell number and sperm production in the adult rats. Thirty-seven neonate Wistar rats were distributed in four groups: control (n=10 and treated with 1mg/kg (n=10, 5mg/kg (n=9, and 10mg/kg (n=8 of pentoxifylline. At 90 days, the animals were submitted to anesthesia and intracardiac perfusion. Testes were colleted and routinely processed for inclusion in plastic resin with glycol methacrylate. Histological sections (4µm were stained in toluidine blue/sodium borate (1% and analyzed. Number of Sertoli cell per transversal section of seminiferous tubule had significant reduction in the groups treated with 5mg/kg and 10mg/kg of pentoxifylline as compared to control and the group that received 1mg/kg (P<0.05. The Sertoli cell index significantly increased in the group treated with 5mg

Survey of environmental radiation dose rates in Kyoto and Shiga prefectures, Japan

International Nuclear Information System (INIS)

Minamia, Kazuyuki; Shimo, Michikuni; Oka, Mitsuaki; Ejiri, Kazutaka; Sugino, Masato; Minato, Susumu; Hosoda, Masahiro; Yamada, Junya; Fukushi, Masahiro

2008-01-01

We have measured environmental radiation dose rates in several Prefectures, such as Ai chi Prefecture, Gifu Prefecture, and Mie Prefecture, in central Japan. Recently, we measured the environmental radiation dose rates in Kyoto and Shiga Prefectures that are also located in central Japan with a car-borne survey system. At the time of measurement, Kyoto Prefecture (area: 4,613 km 2 ) had a total of 36 districts, and Shiga Prefecture (area: 3,387 km 2 ) a total of 26. Terrestrial gamma ray dose rates and secondary cosmic ray dose rates were measured by a 2 inches ψ x 2 inches NaI(Tl) scintillation counter and a handy-type altimeter (GPS eTrex Legend by Gamin), respectively. The following factors were taken into consideration the shielding effect of the car body, the effect of the road pavement, radon progeny borne by precipitation, and increases in tunnels and near the walls. Terrestrial gamma ray dose rates in Kyoto and Shiga Prefectures were estimated to be 51.7 ± 6.0 n Gy/h (district average: 52.4 ± 4.7 n Gy/h), 52.2 ± 10.5 n Gy/h (district average: 51.9 ± 8.1 n Gy/h), respectively. Secondary cosmic ray dose rates in Kyoto and Shiga Prefectures were 30.0 ± 0.6 n Gy/h (district average: 29.9 ±0.3 n Gy/h), 30.1 ± 0.3 n Gy/h (district average: 30.0 ± 0.2 n Gy/h), respectively. The environmental radiation dose rates due to the sum dose rates of terrestrial gamma ray and secondary cosmic ray in Kyoto and Shiga Prefectures were 81.7 ± 6.2 n Gy/h (district average: 82.3 ± 4.8 n Gy/h), 82.3 ± 10.6 n Gy/h (district average: 82.0 ± 8.1 n Gy/h), respectively. We confirmed that the environmental radiation dose rates in Kyoto and Shiga Prefectures mainly depended on the change of the terrestrial gamma ray dose rates, since the secondary cosmic ray dose rates had little change. Therefore, radiation dose-rate maps of the terrestrial gamma rays as well as maps of the environmental radiation dose-rate were drawn. (author)

The colombian private sector and climate change: the road from kyoto

International Nuclear Information System (INIS)

Olander, Jacob

1998-02-01

Because of its profound economic implications, the Kyoto Protocol merits careful study and active, continued participation on the part of the Colombian private sector. The article presents a brief summary of the main elements of the Protocol and its implications for Colombian business. For the business sector in Colombia, Joint implementation has been a key theme in motivating interest and participation on the issue of climate change. Now, after Kyoto, a new instrument has been created, the Clean Development Mechanism, which may permit international investment in forestry and energy projects that reduce greenhouse gas GHG- emissions. The Kyoto Protocol reduces the risk that Colombia need to assume new emissions reductions commitments, and in this new phase it is logical to focus on the opportunities created by the Protocol and the Framework Convention, especially the Clean Development Mechanism. Colombian business leaders should continue to participate actively in the international negotiations that will establish the rules of the game and in the development of private projects in industry, energy and forestry that capture

Bali: an agreement in principle for post-Kyoto negotiations but no emissions reduction targets - Panorama 2008

International Nuclear Information System (INIS)

2008-01-01

Ten years have passed since December 1997, when the United Nations Framework Convention on Climate Change (UNFCCC) was signed in Kyoto. It's been a decade of tough international negotiations, leading to the beginnings of an international CO 2 emissions trading market, whose future past 2012 remains uncertain. The December negotiations in Bali may not have produced a successor to the Kyoto Protocol, but they did get all parties to the Convention to sign an agreement in principle to post- Kyoto negotiations

The Kyoto Protocol : Canada's risky rush to judgement

International Nuclear Information System (INIS)

McKitrick, R.; Wigle, R.M.

2002-01-01

This paper outlined the 4 proposed policy options to implement the Kyoto Protocol in Canada and presented reasons why the Canadian timetable to ratify the Kyoto Protocol is an unrealistic and unsound policy. The Canadian Prime Minister will ask Parliament to ratify the agreement before the end of 2002 but the authors claim that before any decision regarding ratification is made, the government should cost out all relevant options, under all reasonable contingencies. For policy purposes, this paper focuses on reductions of carbon dioxide. Canada's obligation is to reduce them 6 per cent below 1990 levels by 2010, but because of economic growth, emissions among participating countries may be 30 per cent above their aggregate target. In addition, the withdrawal of the United States means that about two-thirds of the world's emissions are not covered by Kyoto. The first policy option involves the selling of emission permits covering about 80 per cent of domestic emitters. It results in 16 MT of domestic emissions reductions being accomplished and 128 MT of foreign permits being purchased. This first option is considered to be the least costly of the four. The second option relies on command-and-control measures in which 104 MT worth of new targeted measures are forced through. Although the government has not provided cost estimates for option 2, it is likely to be much more costly than option 1. The third option slightly adjusts the mix of permits trading and command-and-control measures, and distributes the permits freely instead of selling them. Only the large emitters are involved in the trading system, covering 40 per cent of domestic emission sources. The cost of emissions reductions would be lower than under option 1. The fourth and final option combines tradable permits systems in which only large emitters are involved, but where permits are distributed according to sectoral emission reduction costs, expected future emission growth rates as well as economic

Mapping Land Use Changes for the Kyoto Reporting

DEFF Research Database (Denmark)

Pedersen, Birger Faurholt

Kyoto-rapportering til De Forenede Nationers rammekonvention om klimaændringer (UNFCCC) omfatter en sammenligning af arealanvendelsen i 1990, 2005 og 2008-2012, som er nødvendig for at identificere de ændringer i arealanvendelsen og til at beregne de mulige ændringer i kulstoflagrene. For at udfø...

PEMBIAYAAN RESTRUKTURISASI INDUSTRI BUS PERKOTAAN SESUAI DENGAN KERANGKA KERJA PROTOKOL KYOTO (Funding for Industrial Restructuring Urban Bus Industry following Kyoto Protocol

Directory of Open Access Journals (Sweden)

Danang Parikesit

2002-07-01

Full Text Available ABSTRAK Sektor transportasi, khususnya sektor angkutan umum telah lama disadari sebagai kontributor utama emisi gas rumah kaca (Green House Gases Emissions. Investasi pada angkutan umum perkotaan sangat dibutuhkan walaupun pembiayaan yang konvensional sering sulit dilakukan karena tingginya tingkat investasi dan prioritas pemerintah saat ini. Angkutan perkotaan juga dilihat sebagai daerah kekuasaan sektor swasta yang membuat pemerintah sulit untuk mengeluarkan uang publik. Ratifikasi Kyoto Protocol telah memberi jalan untuk mengembangkan alternatif pembiayaan untuk pembangunan yang berkelanjutan. Clean Development Mechanism pada Kyoto Protocol telah membuka kesempatan bagi otoritas angkutan umum perkotaan dengan menggunakan prinsip carbon trading. Sumber daya untuk menerapkan proyek angkutan umum perkotaan dengan CDM sangat esensial. Pekerjaan di masa datang harus diarahkan untuk mempelajari metodologi dalam mengkombinasi soft measures dan melaksanakan proyek secara optimal. Pembiayaan dengan sistem CDM ini telah dimulai di Yogyakarta dengan judul The Green House Gases Emission Reduction Program for Urban Buses in Yogyakarta atau Program Penurunan Emisi Gas Rumah Kaca untuk Bus Perkotaan di Yogyakarta. Sebuah aliansi dengan nama YUPTA (Yogyakarta Urban Public Transport Alliance telah dibentuk yang terdiri dari 3 lembaga yaitu Dinas Perhubungan Propinsi DIY, Pusat Studi Transportasi dan Logistik (PUSTRAL UGM dan Koperasi Pengusaha Angkutan Kota Yogyakarta (KOPATA.   ABSTRACT Transportation sector, especially public transportation, has been known as the main contributor to the green house hases emission. Investment to urban public transportation is needed but conventional funding is often difficult to be obtained because of the high investment level and the present government priority. Urban transportation is also seen as a private sector domain making the government difficult to use public fund. Kyoto protocol ratification has opened the way to

Comparative morphophysiological evaluation of the testis of adult ...

African Journals Online (AJOL)

olayemitoyin

Wistar rats fed low protein-energy diet and dosed with aqueous extracts ... extracts of C. australis seed and stem, 300mg/kg body weight/day for seven days, on the testis of the adult Wistar rat ..... Modern Study of Traditional Chinese Medicine,.

The costs of the Kyoto Protocol in the European Union

International Nuclear Information System (INIS)

Viguier, Laurent L.; Babiker, Mustafa H.; Reilly, John M.

2003-01-01

We estimate reference CO 2 emission projections in the European Union, and quantify the economic impacts of the Kyoto commitment on Member States. We consider the case where each EU member individually meets a CO 2 emissions target, applying a country-wide cap and trade system to meet the target but without trade among countries. We use a version of the MIT Emissions Prediction and Policy Analysis (EPPA) model, here disaggregated to separately include 9 European Community countries and commercial and household transportation sectors. We compare our results with that of four energy-economic models that have provided detailed analyses of European climate change policy. In the absence of specific additional climate policy measures, the EPPA reference projections of carbon emissions increase by 14% from 1990 levels. The EU-wide target under the Kyoto Protocol to the Framework Convention on Climate Change is a reduction in emissions to 8% below 1990 levels. EPPA emissions projections are similar to other recent modeling results, but there are underlying differences in energy and carbon intensities among the projections. If EU countries were to individually meet the EU allocation of the Community-wide carbon cap specified in the Kyoto Protocol, we find using EPPA that carbon prices vary from $91 in the United Kingdom to $385 in Denmark; welfare costs range from 0.6% to 5%

Studies concerning the effects of low level prenatal X-irradiation on postnatal growth and adult behaviour in the Wistar rat

International Nuclear Information System (INIS)

Jensh, R.P.; Brent, R.L.; Vogel, W.H.

1986-01-01

Fifty-nine pregnant Wistar strain rats were sham irradiated or given a 0.1 or 0.2 Gy exposure of X-radiation on the 9th or 17th day of gestation. Twenty-seven were killed at term for teratologic analysis. The remaining mothers raised their young. At 60 days of age the 252 offspring were randomly assigned three of six tests: open field, swimming, hanging, activity wheel, water T-maze, or conditioned avoidance response. Male offspring exposed at the 0.2 Gy level exhibited retarded growth only during the first few weeks of postnatal life. Female offspring exposed on the 17th day to 0.2 Gy X-radiation were growth retarded throughout the test period. Postnatal growth rates were not significantly different between the irradiated and control groups. There were no significant alterations in adult behaviour due to prenatal X-irradiation. There were sex differences in activity wheel and forelimb hanging performance, unrelated to radiation exposure. These results indicate that prenatal low level X-irradiation on the 9th or 17th day of gestation dose not result in significant alterations in rat adult behavioural performance but prenatal growth retardation persists postnatally. Growth may be a more sensitive indicator of the effects of prenatal exposure than postnatal behaviour. (author)

Greenhouse gas emission trends and projections in Europe 2012. Tracking progress towards Kyoto and 2020 targets

Energy Technology Data Exchange (ETDEWEB)

Gores, S.; Scheffler, M.; Graichen, V. [Oeko-Institut (Oeko), Freiburg (Germany)] [and others

2012-10-15

At the end of 2011, almost all European countries were on track towards their Kyoto targets for 2008-2012. The EU-15 also remained on track to achieve its Kyoto target. Italy, however, was not on track. Spain plans to acquire a large quantity of Kyoto units through the KP's flexible mechanisms to achieve its target. With emission caps already set for the economic sectors under the EU Emissions Trading Scheme (EU ETS), emissions reductions during 2012 in the sectors outside the EU ETS together with reductions by carbon sinks will set the frame for how many Kyoto units Member States need to acquire to reach their individual targets. Hence, both the development and delivery of adequate plans to acquire enough Kyoto credits is becoming increasingly important. ETS emissions from 2008 to 2011 were on average 5 % below these caps, which results in an oversupply of allowances. The EU ETS is undergoing important changes in view of the third trading phase from 2013 to 2020. Most EU Member States project that in 2020, their emissions outside the EU ETS will be lower than their national targets set under the Climate and Energy Package. However, further efforts will be necessary to achieve longer term reductions. (Author)

Estimates of the costs of Kyoto: Marrakesh versus the McKibbin-Wilcoxen blueprint

International Nuclear Information System (INIS)

McKibbin, Warwick J.; Wilcoxen, Peter J.

2004-01-01

In this paper, we update our earlier estimates of the cost of the Kyoto Protocol using the G-Cubed model, taking into account the new sink allowances from recent negotiations as well as allowing for multiple gases and new land clearing estimates. We then compare the protocol to an alternative policy outlined in McKibbin et al. (Brookings Policy Brief, No. 17. June, The Brookings Institution, Washington, 1997; Climate Change Policy After Kyoto: A Blueprint for a Realistic Approach, The Brookings Institution, Washington, 2002a; J. Econom. Perspect. 16(2) (2002b) 107) that does not impose rigid emissions targets. We focus particular attention on the sensitivity of compliance costs under each policy to unexpected changes in future economic conditions. To illustrate the issue, we evaluate the policies under two plausible alternative assumptions about a single aspect of the future world economy: the rate of productivity growth in Russia. We find that moderate growth in Russia would raise the cost of the Kyoto Protocol by as much as 50 percent but would have little effect on the cost of the alternative policy. We conclude that the Kyoto Protocol is inherently unstable because unexpected future events could raise compliance costs substantially and place enormous pressure on governments to abrogate the agreement. The alternative policy would be far more stable because it does not subject future governments to adverse shocks in compliance costs

Structural and Ultrastructural Characteristics of Bone-Tendon Junction of the Calcaneal Tendon of Adult and Elderly Wistar Rats

Science.gov (United States)

Cury, Diego Pulzatto; Dias, Fernando José; Miglino, Maria Angélica; Watanabe, Ii-sei

2016-01-01

Tendons are transition tissues that transfer the contractile forces generated by the muscles to the bones, allowing movement. The region where the tendon attaches to the bone is called bone-tendon junction or enthesis and may be classified as fibrous or fibrocartilaginous. This study aims to analyze the collagen fibers and the cells present in the bone-tendon junction using light microscopy and ultrastructural techniques as scanning electron microscopy and transmission electron microscopy. Forty male Wistar rats were used in the experiment, being 20 adult rats at 4 months-old and 20 elderly rats at 20 months-old. The hind limbs of the rats were removed, dissected and prepared to light microscopy, transmission electron microscopy and scanning electron microscopy. The aging process showed changes in the collagen fibrils, with a predominance of type III fibers in the elderly group, in addition to a decrease in the amount of the fibrocartilage cells, fewer and shorter cytoplasmic processes and a decreased synthetic capacity due to degradation of the organelles involved in synthesis. PMID:27078690

Structural and Ultrastructural Characteristics of Bone-Tendon Junction of the Calcaneal Tendon of Adult and Elderly Wistar Rats.

Directory of Open Access Journals (Sweden)

Diego Pulzatto Cury

Full Text Available Tendons are transition tissues that transfer the contractile forces generated by the muscles to the bones, allowing movement. The region where the tendon attaches to the bone is called bone-tendon junction or enthesis and may be classified as fibrous or fibrocartilaginous. This study aims to analyze the collagen fibers and the cells present in the bone-tendon junction using light microscopy and ultrastructural techniques as scanning electron microscopy and transmission electron microscopy. Forty male Wistar rats were used in the experiment, being 20 adult rats at 4 months-old and 20 elderly rats at 20 months-old. The hind limbs of the rats were removed, dissected and prepared to light microscopy, transmission electron microscopy and scanning electron microscopy. The aging process showed changes in the collagen fibrils, with a predominance of type III fibers in the elderly group, in addition to a decrease in the amount of the fibrocartilage cells, fewer and shorter cytoplasmic processes and a decreased synthetic capacity due to degradation of the organelles involved in synthesis.

Protective Effect of the Persian Gulf brittle star Ophiocoma Erinaceus extract on carbon tetrachloride (CCl4 induced liver damage in adult male Wistar rats

Directory of Open Access Journals (Sweden)

Aida Soheili

2015-12-01

Full Text Available Background and Aim:  Brittle star possess  bioactive compounds which confer the wound healing capacity and regenerative potency of damaged  arms and organisms to this creature. The aim of the current study was to assess the   protective  effect  of  the  star extract on liver damages induced by carbon tetrachloride in adult male Wistar rats. Materials and Methods: In this experimental study, 32 adult male rats were randomly divided into 4 equal groups: control, Sham exposed, experimental 1 (treated with %25 extract and experimental 2 (treated with %50 extract of star Ophiocoma Erinaceus. The control group received no treatment. The sham exposed groups received carbon tetrachloride .(50% in olive oil .0.5 ml/kg for 7 days. The experimental groups firstly received carbon tetrachloride, then received %25, %50 brittle star extract as intragastric for 7 days. Finally, the animals were sacrificed, and their bodies and livers were weighed. Then, the livers sections were prepared and were examined by means of light microscope. Finally, the obtained  quantitative data was analyzed using SPSS (V; 20, Mini Tab software, ANOVA, and Tukey. at the significant level of P<0.001. Results: Carbon tetrachloride significantly decreased the rats’ body weight, but it increased their livers weight (P<0.001. Histopathological evaluations showed .extensive liver damage. On the other hand, treatment with brittle star extract .ncreased liver weight, reduced. body weight and significantly altered other induced changes by carbon tetrachloride on liver structure such as hepatocytes number, Kupffer cells, and arteritis, which indicated  the improvement of damaged liver tissue (P<0.001. Conclusion: It was found that brittle star extract can exert protective effects on  liver damages induced by carbon tetrachloride on male Wistar rat.

Biochemical Effects of Aqueous Extract of Persea americana (Mill) on the Myocardium of Left Ventricle of High Salt-Fed Adult Wistar Rats.

Science.gov (United States)

Olushola, Ayoola I; Aderibigbe, Komolafe O; Stephen, Saka O; Ayodeji, Odukoya S

2017-10-01

The cardioprotective effects of Persea americana extract was investigated on biochemical activities of high salt-fed adult Wistar rats in this study. Forty healthy Wistar rats of both sexes weighing 120 to 150 g were randomly assigned into 8 groups of 5 rats each (groups A, B, C, D, E, F, G, and H). Rats in groups A, F, G, and H were fed with standard laboratory pellets, while groups B, C, D, and E were fed on the high-salt diet for 4 weeks. Concomitantly, daily administration of 50, 100, and 150 mg/kg of the P americana extract were given orally to groups C and F, D and G, and E and H, respectively, while rats in groups A and B were administered distilled water. Blood samples were taken by cardiac puncture; concentration of sodium ion, potassium ion, nitric oxide, and activity of lactate dehydrogenase were determined. One-way analysis of variance was used to analyze data, followed by Student-Newman-Keuls (SNK) test for multiple comparison. Results revealed that concentration of potassium ion and nitric oxide was significantly lower ( P < .05) in high salt-fed groups. Sodium ion concentration and activity of lactate dehydrogenase were higher in high salt-fed group while P americana prevented biochemical perturbations in other experimental groups. In conclusion, high salt-diet induced biochemical alterations which were significantly protected by oral administration of P americana extract.

Impact of the Kyoto Protocol on the Iberian Electricity Market: A scenario analysis

International Nuclear Information System (INIS)

Reneses, Javier; Centeno, Efraim

2008-01-01

This paper presents an assessment of the impact of the Kyoto Protocol on the Iberian Electricity Market during two periods: the first phase (2005-2007) and the second phase (2008-2012). A market-equilibrium model is used in order to analyze different conditions faced by generation companies. Scenarios involving CO 2 -emission prices, hydro conditions, demand, fuel prices and renewable generation are considered. This valuation will show the significance of CO 2 -emission prices as regards Spanish and Portuguese electricity prices, generation mix, utilities profits and the total CO 2 emissions. Furthermore, the results will illustrate how energy policies implemented by regulators are critical for Spain and Portugal in order to mitigate the negative impact of the Kyoto Protocol. In conclusion, the Iberian electricity system will not be able to reach the Kyoto targets, except in very favorable conditions (CO 2 -emission prices over Euro 15/ton and the implementation of very efficient energy policies)

Progress of Fulfillment of the Kyoto Objectives by the European Union

Directory of Open Access Journals (Sweden)

Paul Calanter

2014-05-01

Full Text Available Climate change is one of the most important challenges that humanity faces in the 21st century, which is seriously considered by the European Union. In this context, the objective of this paper is to analyze the extent to which the EU has fulfilled its obligations in the first commitment period of the Kyoto Protocol, and also to expose the obligations stipulated for the second period (2013-2020. The approach is to display in the first part of the work the fulfillment by the European Union of the Kyoto objectives, and in the second part, to analyze the successful implementation in the EU of the flexible mechanisms provided through the Protocol.

Turkish support to Kyoto Protocol: A reality or just an illusion

International Nuclear Information System (INIS)

Erdogdu, Erkan

2010-01-01

The long-term increase in Earth's temperature is known as the global warming or the greenhouse effect. Taking into account the fact that the ice age only involved a global temperature variation of around 4 C, it is clear climate change is arguably one of the greatest environmental threats the world is facing today. The impacts of disruptive change leading to catastrophic events such as storms, droughts, sea level rise and floods are already being felt across the world. In this context, the signing of the Kyoto Protocol in 1997 has been argued to be a historic step in reversing the inexorable increase in the emission of the greenhouse gases. The primary achievement of the Protocol has been so-called commitment of countries referred in the Annex I of the Protocol to reduce their emission of GHGs some 5% below their country specific 1990 level. On February 5, 2009, Turkish Parliament ratified an agreement to sign the Kyoto Protocol after intense pressure from both the European Union and international environmental organizations; however, so far it has not taken any step to bring about real reductions in emissions. In short, Turkey simply signed but ignored the Protocol. Present paper investigates Turkish position vis-a-vis Kyoto Protocol and critically questions Turkish policies in that area. (author)

The Potential of the Market for the Kyoto Mechanisms

International Nuclear Information System (INIS)

Zhang, Z.X.

2000-01-01

The Kyoto Protocol is the first international environmental agreement to set legally binding greenhouse gas (GHG) emissions targets and timetables for Annex I countries. It incorporates emissions trading and two project-based flexibility mechanisms, namely joint implementation (JI) and the clean development mechanism (CDM) to help Annex I countries to meet their Kyoto targets at a lower overall cost. The extent to which their compliance cost can be lowered depends on the size of the market for all three flexibility mechanisms under the Protocol. This article estimates the size of such a market and demonstrates that restrictions on the use of flexibility mechanisms not only reduce potential of the Annex I countries' efficiency gains, but are furthermore not beneficial to developing countries since they restrict the total financial flows to developing countries under the CDM. Thus, from the perspective of husbanding the world's limited resources, the fewer the restrictions on the use of flexibility mechanisms, the greater are the gains from their use

Kyoto protocol and cogeneration in rural areas: institutional and organizational configuration and perspectives; Protocolo de Kyoto e co-geracao no meio rural: configuracao institucional e organizacional e perspectivas

Energy Technology Data Exchange (ETDEWEB)

Souza, Zilmar Jose de; Azevedo, Paulo Furquim de [Fundacao Getulio Vargas (EESP/FGV), Sao Paulo, SP (Brazil). Escola de Economia de Sao Paulo], e-mails: zilmar.souza@energiasdobrasil.com.br, pfa@fgvsp.br

2006-07-01

This article presents a brief historical record concerning the Brazilian institutional arrangement given to the Kyoto Protocol and, based on the Brazilian emissions profile, discusses general perspectives to the use of the CDM, mainly in projects involving co-generation in the agricultural sector. It is observed high uncertainty about the liquidity and development of the carbon credit market, above all, with reference to the definition of the second period of the Kyoto Protocol commitments. Even so, with the consolidation of the institutional environment, the carbon credit market must become favorable to the projects of co-generation in agricultural sector, especially in countries as Brazil. (author)

Kyoto: nuclear power against greenhouse effect

International Nuclear Information System (INIS)

Anon.

1997-01-01

Among the different possibilities to slow down the increase of greenhouse gas emissions, several participants of the Kyoto conference (December 11, 1997) held the nuclear power resort in a good position. This short paper reports on some extracts of talks given during the conference by participants who take a definite position in favour of the development of nuclear power: FORATOM (European Atomic Forum), Nuclear Energy Institute (US), Japan Atomic Industrial Forum, the Uranium Institute, WONUC (World Council of Nuclear Workers) and SFEN (French Society of Nuclear Energy). (J.S.)

Repeated stress exposure causes strain-dependent shifts in the behavioral economics of cocaine in rats

NARCIS (Netherlands)

Groblewski, Peter A.; Zietz, Chad; Willuhn, Ingo; Phillips, Paul E. M.; Chavkin, Charles

2015-01-01

Cocaine-experienced Wistar and Wistar Kyoto (WKY) rats received four daily repeated forced swim stress sessions (R-FSS), each of which preceded 4-hour cocaine self-administration sessions. Twenty-four hours after the last swim stress, cocaine valuation was assessed during a single-session threshold

Nursing in Modern Japan and its Significance: The Kyoto Training School for Nurses and the Kyoto Nursing School

OpenAIRE

小野, 尚香

2003-01-01

Nursing by Buddhist during Meiji Japan was stimulated by the visiting nursing program conducted by nurses connected with the Kyoto Training School for Nurses. Why were Buddhist priests attracted to the visiting nursing. what did they try to adopt and what kind of nursing activities did they try to organize? As the first step to answer these questions. in this paper I considered the specialty. the sociality. and the nursing spirit of the home nursing and district nursing provided by the ...

Considering WTO law in the design of climate change regimes beyond Kyoto

Science.gov (United States)

Gaines, Sanford E.

2009-11-01

This article describes the most important provisions of World Trade Organization (WTO) agreements that should be considered in designing laws and regulations under likely post-Kyoto climate change mitigation regimes. The Kyoto Protocol and the expected post-Kyoto international climate agreement depend on national measures to implement market-based mitigation measures. This market strategy promotes international exchanges of goods, investments, and services such as cross-border trading of credits for emissions reductions and transnational financing for projects that avoid emissions through the Clean Development Mechanism. Moreover, the United States and other countries, concerned over "leakage" of greenhouse gas (GHG) emissions through relocation of industry to other countries coupled with political worry over manufacturing competitiveness, have proposed national climate legislation containing border adjustments on imported goods or implicit subsidies for national producers, raising additional WTO considerations. The article assesses the likely effectiveness of such trade-related measures in achieving climate change mitigation goals and the potential trade policy infringements and trade distortions that they might bring about. Alternative strategies for achieving GHG mitigation goals in closer conformity with WTO law and policy will be suggested.

Considering WTO law in the design of climate change regimes beyond Kyoto

International Nuclear Information System (INIS)

Gaines, Sanford E

2009-01-01

This article describes the most important provisions of World Trade Organization (WTO) agreements that should be considered in designing laws and regulations under likely post-Kyoto climate change mitigation regimes. The Kyoto Protocol and the expected post-Kyoto international climate agreement depend on national measures to implement market-based mitigation measures. This market strategy promotes international exchanges of goods, investments, and services such as cross-border trading of credits for emissions reductions and transnational financing for projects that avoid emissions through the Clean Development Mechanism. Moreover, the United States and other countries, concerned over 'leakage' of greenhouse gas (GHG) emissions through relocation of industry to other countries coupled with political worry over manufacturing competitiveness, have proposed national climate legislation containing border adjustments on imported goods or implicit subsidies for national producers, raising additional WTO considerations. The article assesses the likely effectiveness of such trade-related measures in achieving climate change mitigation goals and the potential trade policy infringements and trade distortions that they might bring about. Alternative strategies for achieving GHG mitigation goals in closer conformity with WTO law and policy will be suggested.

Monte Carlo Analysis of the Accelerator-Driven System at Kyoto University Research Reactor Institute

Directory of Open Access Journals (Sweden)

Wonkyeong Kim

2016-04-01

Full Text Available An accelerator-driven system consists of a subcritical reactor and a controllable external neutron source. The reactor in an accelerator-driven system can sustain fission reactions in a subcritical state using an external neutron source, which is an intrinsic safety feature of the system. The system can provide efficient transmutations of nuclear wastes such as minor actinides and long-lived fission products and generate electricity. Recently at Kyoto University Research Reactor Institute (KURRI; Kyoto, Japan, a series of reactor physics experiments was conducted with the Kyoto University Critical Assembly and a Cockcroft–Walton type accelerator, which generates the external neutron source by deuterium–tritium reactions. In this paper, neutronic analyses of a series of experiments have been re-estimated by using the latest Monte Carlo code and nuclear data libraries. This feasibility study is presented through the comparison of Monte Carlo simulation results with measurements.

Monte Carlo analysis of the accelerator-driven system at Kyoto University Research Reactor Institute

Energy Technology Data Exchange (ETDEWEB)

Kim, Won Kyeong; Lee, Deok Jung [Nuclear Engineering Division, Ulsan National Institute of Science and Technology, Ulsan (Korea, Republic of); Lee, Hyun Chul [VHTR Technology Development Division, Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Pyeon, Cheol Ho [Nuclear Engineering Science Division, Kyoto University Research Reactor Institute, Osaka (Japan); Shin, Ho Cheol [Core and Fuel Analysis Group, Korea Hydro and Nuclear Power Central Research Institute, Daejeon (Korea, Republic of)

2016-04-15

An accelerator-driven system consists of a subcritical reactor and a controllable external neutron source. The reactor in an accelerator-driven system can sustain fission reactions in a subcritical state using an external neutron source, which is an intrinsic safety feature of the system. The system can provide efficient transmutations of nuclear wastes such as minor actinides and long-lived fission products and generate electricity. Recently at Kyoto University Research Reactor Institute (KURRI; Kyoto, Japan), a series of reactor physics experiments was conducted with the Kyoto University Critical Assembly and a Cockcroft-Walton type accelerator, which generates the external neutron source by deuterium-tritium reactions. In this paper, neutronic analyses of a series of experiments have been re-estimated by using the latest Monte Carlo code and nuclear data libraries. This feasibility study is presented through the comparison of Monte Carlo simulation results with measurements.

Market-based implementation of Kyoto commitments: how the financial/insurance sector can support industry

International Nuclear Information System (INIS)

Knoepfel, Ivo

1999-01-01

The implementation of the Kyoto Protocol in the context of the Framework Convention on Climate Change will probably lead to economic winners and losers in various sectors of the economy. Especially carbon intensive industries will need to develop hedging strategies to prevent potential negative effects and to optimise market opportunities. Such strategies can be based on technological innovation, market and product diversification, and on financial/legal offsets. The Kyoto Protocol has introduced new market-based instruments, which can, in a near future provide such hedging opportunities. These include joint implementation, the so-called clean development mechanism, and international emissions trading. The financial services and insurance sector are the natural partners of industry in designing tailored hedging strategies. It is recommended that industry, financial services and insurance companies take a more proactive role in further developing the market-based instruments established by the Kyoto Protocol. (Author)

Research on neutron radiography in Research Reactor Institute, Kyoto University and activities related to it

International Nuclear Information System (INIS)

Fujine, Shigenori; Yoneda, Kenji

1994-01-01

The research on neutron radiography in Research Reactor Institute, Kyoto University was begun in 1974 using the E-2 experimental hole which was designed for neutron irradiation. It was reconstructed for the excellent performance as neutron radiography facility by fixing aluminum plugs, a collimator and so on. The research activities thereafter are briefly described. In 1989, the cold neutron facility was installed in the graphite thermal neutron facility, and the experiment on cold neutron radiography became feasible. The reactor in Kyoto University is of the thermal output of 5 MW, and is put to the joint utilization by universities and research institutes in whole Japan. The experimental items carried out so far are enumerated. At present, the main subjects of research are the development of the standard for establishing image evaluation method, the analysis of gas-liquid two-phase flow, the construction of the data base for the literatures and images of neutron radiography, the application of cold neutron radiography, the development of the imaging method using fast neutrons and so on. The thermal neutron radiography and the cold neutron radiography facilities of Kyoto University research reactor are described. The research and activities at Kyoto University research reactor and the investigation of problems are reported. (K.I.) 56 refs

Association between gastric cancer and the Kyoto classification of gastritis.

Science.gov (United States)

Shichijo, Satoki; Hirata, Yoshihiro; Niikura, Ryota; Hayakawa, Yoku; Yamada, Atsuo; Koike, Kazuhiko

2017-09-01

Histological gastritis is associated with gastric cancer, but its diagnosis requires biopsy. Many classifications of endoscopic gastritis are available, but not all are useful for risk stratification of gastric cancer. The Kyoto Classification of Gastritis was proposed at the 85th Congress of the Japan Gastroenterological Endoscopy Society. This cross-sectional study evaluated the usefulness of the Kyoto Classification of Gastritis for risk stratification of gastric cancer. From August 2013 to September 2014, esophagogastroduodenoscopy was performed and the gastric findings evaluated according to the Kyoto Classification of Gastritis in a total of 4062 patients. The following five endoscopic findings were selected based on previous reports: atrophy, intestinal metaplasia, enlarged folds, nodularity, and diffuse redness. A total of 3392 patients (1746 [51%] men and 1646 [49%] women) were analyzed. Among them, 107 gastric cancers were diagnosed. Atrophy was found in 2585 (78%) and intestinal metaplasia in 924 (27%). Enlarged folds, nodularity, and diffuse redness were found in 197 (5.8%), 22 (0.6%), and 573 (17%), respectively. In univariate analyses, the severity of atrophy, intestinal metaplasia, diffuse redness, age, and male sex were associated with gastric cancer. In a multivariate analysis, atrophy and male sex were found to be independent risk factors. Younger age and severe atrophy were determined to be associated with diffuse-type gastric cancer. Endoscopic detection of atrophy was associated with the risk of gastric cancer. Thus, patients with severe atrophy should be examined carefully and may require intensive follow-up. © 2017 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.

The compatibility of flexible instruments under the Kyoto Protocol

International Nuclear Information System (INIS)

Jepma, C.J.; Van der Gaast, W.P.; Woerdman, E.

1998-01-01

The compatibility of the Kyoto Protocol flexible instruments and the lessons that can be learned form the AIJ-phase (AIJ stands for Activities Implemented Jointly) are discussed. The key point to be made is that there may be various applications of flexible instruments which can create situations where the various instruments would crowd out each other. On the other hand, applying flexible instruments may create a leverage for Parties in terms of achieving domestic environmental objectives. In addition, several issues related to the implementation of Joint Implementation (JI) , Clean Development Mechanism (CDM) and international emissions trading are discussed. The issues concern mainly those that have been included in the working programme on flexible instruments for CoP4 and CoP5 (CoP stands for Convention of Parties). As such the report discusses the consequences of possible negotiations outcomes at CoP for the effectiveness of flexible instruments, Parties' capabilities to achieve their Kyoto Protocol commitments cost-effectively, and the role of the private sector on the national and international credits markets(s). 106 refs

Response by the energy industry to the Kyoto agreement

International Nuclear Information System (INIS)

Lynch, M.C.

2000-01-01

The Kyoto agreement has called for an appropriate response by the energy industry to the perceived problem of global warming. However, while governments are justify in researching low-probability energy technologies to solve uncertain problems, the private sector has non such luxury. The experience of oil crises in the '70s should be a good lesson [it

Experimental model of intervertebral disc degeneration by needle puncture in Wistar rats

International Nuclear Information System (INIS)

Issy, A.C.; Castania, V.; Castania, M.; Salmon, C.E.G.; Nogueira-Barbosa, M.H.; Bel, E. Del; Defino, H.L.A.

2013-01-01

Animal models of intervertebral disc degeneration play an important role in clarifying the physiopathological mechanisms and testing novel therapeutic strategies. The objective of the present study is to describe a simple animal model of disc degeneration involving Wistar rats to be used for research studies. Disc degeneration was confirmed and classified by radiography, magnetic resonance and histological evaluation. Adult male Wistar rats were anesthetized and submitted to percutaneous disc puncture with a 20-gauge needle on levels 6-7 and 8-9 of the coccygeal vertebrae. The needle was inserted into the discs guided by fluoroscopy and its tip was positioned crossing the nucleus pulposus up to the contralateral annulus fibrosus, rotated 360° twice, and held for 30 s. To grade the severity of intervertebral disc degeneration, we measured the intervertebral disc height from radiographic images 7 and 30 days after the injury, and the signal intensity T2-weighted magnetic resonance imaging. Histological analysis was performed with hematoxylin-eosin and collagen fiber orientation using picrosirius red staining and polarized light microscopy. Imaging and histological score analyses revealed significant disc degeneration both 7 and 30 days after the lesion, without deaths or systemic complications. Interobserver histological evaluation showed significant agreement. There was a significant positive correlation between histological score and intervertebral disc height 7 and 30 days after the lesion. We conclude that the tail disc puncture method using Wistar rats is a simple, cost-effective and reproducible model for inducing disc degeneration

Experimental model of intervertebral disc degeneration by needle puncture in Wistar rats

Energy Technology Data Exchange (ETDEWEB)

Issy, A.C.; Castania, V.; Castania, M. [Departamento de Morfologia, Fisiologia e Patologia Básica, Faculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP (Brazil); Salmon, C.E.G. [Departamento de Física, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP (Brazil); Nogueira-Barbosa, M.H. [Divisão de Radiologia, Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP (Brazil); Bel, E. Del [Departamento de Morfologia, Fisiologia e Patologia Básica, Faculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP (Brazil); Defino, H.L.A. [Departamento de Biomecânica, Medicina e Reabilitação do Sistema Locomotor, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP (Brazil)

2013-03-15

Animal models of intervertebral disc degeneration play an important role in clarifying the physiopathological mechanisms and testing novel therapeutic strategies. The objective of the present study is to describe a simple animal model of disc degeneration involving Wistar rats to be used for research studies. Disc degeneration was confirmed and classified by radiography, magnetic resonance and histological evaluation. Adult male Wistar rats were anesthetized and submitted to percutaneous disc puncture with a 20-gauge needle on levels 6-7 and 8-9 of the coccygeal vertebrae. The needle was inserted into the discs guided by fluoroscopy and its tip was positioned crossing the nucleus pulposus up to the contralateral annulus fibrosus, rotated 360° twice, and held for 30 s. To grade the severity of intervertebral disc degeneration, we measured the intervertebral disc height from radiographic images 7 and 30 days after the injury, and the signal intensity T2-weighted magnetic resonance imaging. Histological analysis was performed with hematoxylin-eosin and collagen fiber orientation using picrosirius red staining and polarized light microscopy. Imaging and histological score analyses revealed significant disc degeneration both 7 and 30 days after the lesion, without deaths or systemic complications. Interobserver histological evaluation showed significant agreement. There was a significant positive correlation between histological score and intervertebral disc height 7 and 30 days after the lesion. We conclude that the tail disc puncture method using Wistar rats is a simple, cost-effective and reproducible model for inducing disc degeneration.

Health Status of Male Adult Wistar Rats from Two Experimental Animal Houses of UFMG: Leukocyte Counts, Feces and Lung Histological Exams

Directory of Open Access Journals (Sweden)

Andrade Bruno Horta

2002-01-01

Full Text Available A study was conducted to compare health status of male adult Wistar rats from two Experimental Animal Houses of UFMG with literature data of SPF (free from specific pathogens and conventional rats. The animals were divided into two groups: Group I (n=10, rats from the experimental animal houses of FAFICH and Group II (n=10 from ICB and following aspects were studied: a evident clinical signs (behavior modification, hair loss (alopecia, b leukocyte counts, c feces exam and d histological study of the lungs. The rats did not show clinical signs. However, when compared with SPF and conventional rats, both the groups showed a significant increase (p<0,05 of leukocyte count. On feces exam we detected some parasites and on lung histological exam we observed fungus (Group I and bacteria (Group II. These results showed that the health status of the rats was not satisfactory and required improvements in the conditions of the animal houses.

Greenhouse gas emission trends and projections in Europe 2011. Tracking progress towards Kyoto and 2020 targets

Energy Technology Data Exchange (ETDEWEB)

Busche, J.; Scheffler, M.; Graichen, V. (Umweltbundesamt, Vienna (Austria)) (and others)

2011-10-15

At the end of 2010, the EU-15 was on track to achieve its Kyoto target but three EU-15 Member States (Austria, Italy and Luxembourg) were not on track to meet their burden-sharing targets. These countries must therefore seriously consider further action to ensure compliance, in particular revising their plans on using flexible mechanisms. Among the EEA member countries outside the EU, Liechtenstein and Switzerland were not on track to achieve their Kyoto target at the end of 2009. All other European countries are on track to meet their targets, either based on domestic emissions only or with the assistance of Kyoto mechanisms. The economic recession had a significant impact on the EU's total greenhouse gas (GHG) emission trends but a more limited effect on progress towards Kyoto targets. This is because emissions in the sectors covered by the EU Emissions Trading Scheme (ETS), which were most affected by the crisis, do not affect Kyoto compliance once ETS caps have been set. With existing national measures, Member States do not project enough emission reductions for the EU to meet its unilateral 20 % reduction commitment in 2020. Additional measures currently planned by Member States will help further reduce emissions but will be insufficient to achieve the important emission cuts needed in the longer term. By 2020 Member States must enhance their efforts to reduce emissions in non-EU ETS sectors, such as the residential, transport or agriculture sectors, where legally binding national targets have been set under the EU's 2009 climate and energy package. (Author)

Kyoto and the greenhouse effect economy. CEA report n.39; Kyoto et l'economie de l'effet de serre. Rapport du CEA n.39

Energy Technology Data Exchange (ETDEWEB)

Guesnerie, R.; Champsaur, P.; Lipietz, A

2003-07-01

This economic analysis deals with the necessary efforts to fight the climatic change and the kyoto protocol efficiency. In this framework this study shows how, in this domain, the economic calculation is important for the decision making. (A.L.B.)

From small to insignificant. Climate impact of the Kyoto Protocol with and without US

International Nuclear Information System (INIS)

Hagem, Cathrine; Holtsmark, Bjart

2001-06-01

American president George W. Bush has declared that he will not ask the Senate to ratify the Kyoto Protocol. This commentary explores the potential impact of implementing the Kyoto Protocol without the participation of the United States. Because, in practice, the United States would have taken on a relatively large share of the Protocol's abatement commitments, we conclude that implementing the Protocol without the participation of United States will lead to significantly less reductions in global emissions. The international permit price will be considerably lower if the United States does not participate. (author)

The Kyoto Protocol Emissions Trading Mechanisms - A Model for financing future nuclear development in Romania

International Nuclear Information System (INIS)

Purica, Ionut; John Saroudis

2001-01-01

At the beginning of 2001 Romania ratified the Kyoto Protocol (Law 3/2001) thus becoming the first European country to do so. The mechanisms of the Kyoto Protocol are now opening new ways to sponsor the financing of nuclear projects. In May 2001 Societatea Nationala Nuclearoelectrica S.S. (SNN) and Atomic Energy of Canada Limited and ANSALDO of Italy signed a contract to complete the second CANDU unit at Cernavoda thus giving a new momentum to the nuclear program in Romania. The Government of Romania has indicated its desire to proceed with the completion of the other units on the Cernavoda site and is open to explore every potential financing mechanism to make this a reality. Although the Kyoto Protocol was not ratified by those countries that have the greatest need to reduce emissions, a market for emissions trading has developed, Canada being one of the important players in this market. Since the emission reduction per dollar invested in the Romanian nuclear program would bring much more reduction than the marginal reduction per dollar invested in environmental protection programs in Canada, where the saturation effect is already taking place, we consider that the application of the Kyoto Protocol mechanisms represents a realistic source for a sustainable cooperation of the two countries. This trend is in line with the latest activities of the International Atomic Energy Agency (IAEA). This paper analyzes the impact that the use of emissions credits would have on a typical financing scheme for a future CANDU project in Romania given the present situation and also proposes a model for the structure of the emissions trade that would generate a source of funding for the project. The conclusion is that there is real potential in using Kyoto Protocol mechanisms for financing nuclear development with benefits for both Romania and Canada. (authors)

[Beginnings of the study of Western sciences, "Rangaku," in Kyoto and Osaka in close relations with the Edo school].

Science.gov (United States)

Murata, T

2001-01-01

Beginnings of the study of Western sciences, "Rangaku," in Kyoto and Osaka in the late 18th century are reviewed. Profiles and achievements of several active learners are briefly described; they include Koishi Genzui (Osaka-Kyoto), Tsuji Ranshitsu (Kyoto), Kimura Kenkadō (Osaka), and Hashimoto Sōkichi (Osaka). Genzui, after having successfully made good relations with Sugita Genpaku and Ohtsuki Gentaku, leading masters of the Edo school, played a role of an advocator for promoting "Rangaku" in Osaka and Kyoto. As a result, Kenkadō attained the publication of his book "Ikkaku Sankō," a monograph of the Western crude drug unicorn, with the help of Gentaku, who had translated a Dutch reference into Japanese for him. Ranshitsu and Sōkichi were taught the Dutch language by Gentaku; Sōkichi is known as the founder of "Rangaku" in Osaka.

The environmental agreement may lead to large losses for the oil producers. The Kyoto mechanisms are very important to Norway

International Nuclear Information System (INIS)

1999-01-01

The article presents an economic model study of the implications of an climatic agreement. Two main scenarios are presented: 1) The Kyoto protocol is extended to 2020. 2) All counties ratify a climatic agreement. The conclusions are that the Kyoto protocol may have great effects on the oil and gas markets and large economic consequences for Norway. It is therefore mandatory to extensively use the Kyoto mechanisms such as trade with quotas, common implementation and the green development mechanism

Kyoto and the absence of leadership in Canada's capitals

Energy Technology Data Exchange (ETDEWEB)

Urquhart, I. [Alberta Univ., Dept. of Political Science, Edmonton, AB (Canada)

2003-01-01

A critique of Alberta's response to the Kyoto Protocol is presented. According to this author, Alberta's approach rests on a dubious foundation and is therefore 'wrongheaded'. Rather than being the economic disaster as characterized by the provincial government and the oil industry, the implementation costs of the Kyoto Protocol are likely to be much more incremental than Alberta's apocalyptic scenario suggests. With respect to cost, the author bolsters his case by citing the experience of British Petroleum Limited which has already reduced GHG emissions to 10 per cent below 1990 levels at 'no economic cost'. He argues that the 'made-in-Canada' environmental policy suggested by Alberta is no more likely to succeed than did the 'made-in-Canada' oil price policy in 1980. He makes a strong argument for the Kyoto Protocol as an opportunity to create federal-provincial strategies for all of Canada, and makes a strong case for institutional changes that would respect the legitimacy of federal and provincial interests in environmental policy issues. Given genuine effective leadership in Ottawa and in the provincial capitals, such changes could be an important step in the direction of increased reliance on one another as we try to secure a better future for all Canadians, and at the same time doing our bit in ensuring the survival of the planet.

Kyoto and the economics of global warming; Kyoto et l'economie de l'effet de serre

Energy Technology Data Exchange (ETDEWEB)

Guesnerie, R

2003-07-01

This report sheds light on the economic issues surrounding climate change. The objective is to fuel a longer term reflexions. The greenhouse effect raises many questions dealing with economic policy. In particular what is the right agenda for action taking into account the low reversibility of the increasing concentration of greenhouse gases? What about the Kyoto protocol architecture? How to deal with countries that will not participate in the effort for controlling emissions, while enjoying the benefits of the preservation of the climate, a collective good? How to protect the competitiveness of countries that impose environmental constraints on their producers? This report is then discussed by P. Champsaur and A. Lipietz. (A.L.B.)

The Kyoto Protocol and the coal industry in Colombia

International Nuclear Information System (INIS)

Viana Rubio, Edgar

1998-02-01

In this article is studied the possible incidence of the commitments reached in the Kyoto Protocol on the coal market, making emphasis in the Colombian case. Projections, made in a study of Hill y Associates, points out that in a scenario of greenhouse gases emissions reduction, the market of the thermal coal will be seriously affected by the incidence on their demand

Global property rights. The Kyoto protocol and the knowledge revolution

International Nuclear Information System (INIS)

Chichilnisky, G.

2006-01-01

This paper is about the origin of today's global environmental problems, and how to resolve them. At stake are catastrophic risks from global warming and damage to the world's biodiversity that ranks as the planet' sixth great extinction. The origin of today's global environmental problems is a historic difference in property rights regimes between industrial and developing countries, the North and the South. The solutions we suggest involve redefining property rights in the use of the global environment as well as in knowledge. We discuss the Kyoto Protocol's new systems of property rights on the use of the planet's atmosphere, and propose a parallel system of property rights on knowledge. Resources such as forests and oil and other mineral deposits are owned as private property in industrial countries but they are treated as common or government property in developing countries. Ill-defined protected property rights lead to the over-extraction of resources in the South, such as timber and oil. They are exported at low prices to the North that over-consumes them. The international market amplifies the tragedy of the commons, leading to inferior solutions for the world economy as a whole (Chichilnisky 1994). Updating property rights on resources in developing countries would face formidable opposition. The lack of property rights in inputs to production, such as timber and oil, could be compensated by assigning property rights on by-products of outputs. The 1997 Kyoto Protocol provides an example as it limits the countries' rights to emit carbon, a by-product of burning fossil fuels. Our suggestions for trading emissions rights (Chichilnisky 1995, 96) was adopted in the Kyoto Protocol, yet the atmosphere's carbon concentration is a global public good, which makes trading tricky. Trading rights to forests' carbon sequestration services or to genetic blueprints would also be trading global public goods. Markets that trade public goods have been shown to require a

Canada's nuclear industry, greenhouse gas emissions, and the Kyoto Protocol

International Nuclear Information System (INIS)

Pendergast, D.R.; Duffey, R.B.; Tregunno, D.

1998-01-01

The Kyoto Protocol of the United Nations Framework Convention on Climate change, dated December 10, 1997 committed Canada to reduce greenhouse gases to 6% below 1990 levels by 2008-2012. Other nations also committed to varying degrees of reduction. The Protocol includes provisions for credit to the 'developed' counties for initiatives which lead to greenhouse gas reduction in the 'developing' countries and for the sharing of credit between 'developed' countries for projects undertaken jointly. The rules and details for implementation of these guidelines remain to be negotiated. We begin our study by establishing the magnitude of greenhouse gas emissions already avoided by the nuclear industry in Canada since the inception of commercial power plants in 1971. We then review projections of energy use in Canada and anticipated increase in electricity use up to the year 2020. These studies have anticipated no (or have 'not permitted') further development of nuclear electricity production in spite of the clear benefit with respect to greenhouse gas emission. The studies also predict a relatively small growth of electricity use. In fact the projections indicate a reversal of a trend toward increased per capita electricity use which is contrary to observations of electricity usage in national economies as they develop. We then provide estimates of the magnitude of greenhouse gas reduction which would result from replacing the projected increase in fossil fuel electricity by nuclear generation through the building of more plants and/or making better use of existing installations. This is followed by an estimate of additional nuclear capacity needed to avoid CO 2 emissions while providing the electricity needed should per capita usage remain constant. Canada's greenhouse gas reduction goal is a small fraction of international commitments. The Kyoto agreement's 'flexibility mechanism' provisions provide some expectation that Canada could obtain some credit for greenhouse gas

Nature and nurture: environmental influences on a genetic rat model of depression.

Science.gov (United States)

Mehta-Raghavan, N S; Wert, S L; Morley, C; Graf, E N; Redei, E E

2016-03-29

In this study, we sought to learn whether adverse events such as chronic restraint stress (CRS), or 'nurture' in the form of environmental enrichment (EE), could modify depression-like behavior and blood biomarker transcript levels in a genetic rat model of depression. The Wistar Kyoto More Immobile (WMI) is a genetic model of depression that aided in the identification of blood transcriptomic markers, which successfully distinguished adolescent and adult subjects with major depressive disorders from their matched no-disorder controls. Here, we followed the effects of CRS and EE in adult male WMIs and their genetically similar control strain, the Wistar Kyoto Less Immobile (WLI), that does not show depression-like behavior, by measuring the levels of these transcripts in the blood and hippocampus. In WLIs, increased depression-like behavior and transcriptomic changes were present in response to CRS, but in WMIs no behavioral or additive transcriptomic changes occurred. Environmental enrichment decreased both the inherent depression-like behavior in the WMIs and the behavioral difference between WMIs and WLIs, but did not reverse basal transcript level differences between the strains. The inverse behavioral change induced by CRS and EE in the WLIs did not result in parallel inverse expression changes of the transcriptomic markers, suggesting that these behavioral responses to the environment work via separate molecular pathways. In contrast, 'trait' transcriptomic markers with expression differences inherent and unchanging between the strains regardless of the environment suggest that in our model, environmental and genetic etiologies of depression work through independent molecular mechanisms.

UNFINISHED BUSINESS: The Economics of The Kyoto Protocol

Energy Technology Data Exchange (ETDEWEB)

JA Edmonds; CN MacCracken; RD Sands; SH Kim

2000-07-06

The Kyoto Protocol to the Framework Convention on Climate Change (FCCC) was completed on the morning of December 11, 1997, following over two years of negotiations. The product of these deliberations is a complex and incomplete document knitting together the diversity of interests and perspectives represented by the more than 150 delegations. Because the document is complex, its implications are not immediately obvious. If it enters into force, the Kyoto Protocol will have far-reaching implications for all nations--both nations with obligations under the Protocol and those without obligations. National energy systems, and the world's energy system, could be forever changed. In this paper the authors develop an assessment of the energy and economic implications of achieving the goals of the Kyoto Protocol. They find that many of the details of the Protocol that remain to be worked out introduce critical uncertainties affecting the cost of compliance. There are also a variety of uncertainties that further complicate the analysis. These include future non-CO{sub 2} greenhouse gas emissions and the cost of their mitigation. Other uncertainties include the resolution of negotiations to establish rules for determining and allocating land-use emissions rights, mechanisms for Annex 1 trading, and participation by non-Annex 1 members in the Clean Development Mechanism. In addition, there are economic uncertainties, such as the behavior of Eastern Europe and the former Soviet Union in supplying emissions credits under Annex 1 trading. These uncertainties in turn could affect private sector investments in anticipation of the Protocol's entrance into force. The longer the nature of future obligations remains unclear, the less able decision makers will be to incorporate these rules into their investment decisions. They find that the cost of implementing the Protocol in the US can vary by more than an order of magnitude. The marginal cost could be as low as $26 per

Kyoto discord: who bears the cost?

International Nuclear Information System (INIS)

Rubin, J.; Buchanan, P.

2002-01-01

Since 1990, Canada's greenhouse gas emissions are up 20 per cent, meaning that Canada must reduce its emissions by 30 per cent between 2005 and 2010 to meet its commitment under the Kyoto Protocol. Ottawa has indicated that no one sector of the economy should bear the burden of this adjustment. The energy production sector accounts for almost 40 per cent of all greenhouse gas emissions. Our per capita emissions have risen 50 per cent faster than emissions in the United States. The authors compared our situation to that of Europe, where only a 5 per cent reduction is required, which can be explained by high taxes on energy users, and the closure of obsolete East German capacity which led to reductions of 100 million tonne in carbon dioxide emissions. Transportation is the second largest generator of greenhouse gas emissions with approximately 16 per cent. A quick overview of the energy sector was provided, touching on topics such as electric power generation, including coal-fired electrical production, and tar sands with its increasing importance to Canada's economy. Ottawa has released a plan in October 2002, where it indicates that industrial emitters will be required to cut 80 million tonnes through investments in more efficient technology. Tighter vehicle fuel and home insulation standards would account for 35 to 40 million tonnes of reduction, and 40 million tonnes would come from agriculture and forest management. It means there is a 60 million shortfall, and the tar sands industry will more than likely have to adjust, raising investor uncertainty over further development in that area. Climate change is unlikely to be modified by meeting the objectives of the Kyoto Protocol. The authors questioned whether the government shouldn't instead devote its resources to addressing the actual impact of climate change. 9 figs

A Comment on Kyoto and Electricity Generation in Croatia

International Nuclear Information System (INIS)

Knapp, V.

1998-01-01

Kyoto convention signed in December 1997 will, pending ratification, introduce legal obligations to countries of Annex I of the Convention to reduce CO 2 emission. Reductions will be obligatory for a number of small and medium European countries. Croatia will have to reduce its emission to 95% of the 1990 level. Possibility to meet this target without the use of new nuclear facility is doubtful. (author)

A project for increasing the rate of participation in mammographic breast cancer screening in Kyoto prefecture to 50%

International Nuclear Information System (INIS)

Nakajima, Hiroo; Fujiwara, Ikuya; Mizuta, Naruhiko; Sakaguchi, Koichi; Hachimine, Yasushi; Kageyama, Norio; Sawai, Kiyoshi; Nishida, Naoko

2007-01-01

The rate of participation in breast cancer screening carried out by inspection and palpation associated with mammography in Kyoto Prefecture has been still low. In order to decrease the rate of breast cancer death, a high rate of screening participation must be achieved. We have organized the Kyoto Executive Committee of Pink Ribbon Activity aiming at the goal of achieving a 50% rate of participation in mammography screening by the end of 2010, and undertaken the following campaign activities: performing free screening, distribution and display of posters and leaflets about breast cancer screening, cooperation with various media to spread educational and informative messages, cooperation with a commercial institute in Kyoto City to distribute useful information, performing free breast cancer screening, and holding public lecture meetings, distribution of leaflets at student festivals at universities and colleges in Kyoto, and holding a ''Pink Ribbon symposium'' in a cosponsored company. All the above projects were performed successfully and many participants attended. We will continue these activities until the 50% participation rate is achieved. (author)

Safety considerations of new critical assembly for the Research Reactor Institute, Kyoto University

International Nuclear Information System (INIS)

Umeda, Iwao; Matsuoka, Naomi; Harada, Yoshihiko; Miyamoto, Keiji; Kanazawa, Takashi

1975-01-01

The new critical assembly type of nuclear reactor having three cores for the first time in the world was completed successfully at the Research Reactor Institute of Kyoto University in autumn of 1974. It is called KUCA (Kyoto University Critical Assembly). Safety of the critical assembly was considered sufficiently in consequence of discussions between the researchers of the institute and the design group of our company, and then many bright ideas were created through the discussions. This paper is described the new safety design of main equipments - oil pressure type center core drive mechanism, removable water overflow mechanism, core division mechanism, control rod drive mechansim, protection instrumentation system and interlock key system - for the critical assembly. (author)

[Offsets under the Kyoto Protocol : a perspective on COP 4 negotiations

International Nuclear Information System (INIS)

Kelly, E.

1998-01-01

The achievements of the Kyoto Protocol were highlighted. These achievements include recognition of the need for Annex 1 countries (developed countries) to define concrete emissions reduction targets to be accomplished by 2012; recognition of specific needs of developing countries; need for measures to anticipate, prevent or minimize the causes of climate change; recognition of the need that climate change policies and measures be cost effective; taking into account that economic development is essential for adopting measures to address climate change; recognition of the principle that corporations should promote a supportive and open international economic system leading to sustainable growth; and recognition that measures taken to combat climate change should not lead to unjustifiable discrimination in international trade. If the targets set at Kyoto are achieved, there will be an effective reduction in greenhouse gases of 5.2 per cent in relation to 1990 levels. The meeting in Buenos Aires should focus on strengthening the guidelines for actions agreed upon in Kyoto. Other major issues on the Buenos Aires Conference of Parties (COP 4) agenda should be to discuss ways and means to helping developing countries to deal with climate change issues within their own territories, agreement about definitive status of the Global Environmental Fund, arriving at a more precise definition of the Clean Development Mechanism, and first and foremost the development of credible national systems (i.e. Annex 1 countries) for the estimation of anthropogenic emission sources and removal by sinks of all greenhouse gases not controlled by the Montreal Protocol on the Ozone Layer, and shaping an adequate non-compliance system

Kyoto protocol at the convention of united nations about the climatic changes

International Nuclear Information System (INIS)

Anon.

1998-01-01

The engagements to reduce the emissions of greenhouse gases by industrialized countries at Kyoto on the 10. of December 1997 are explained and discussed. The text of the agreement is given in its entirety. (N.C.)

Takeaway sushiravintolan liiketoimintasuunnitelman laadinta: Miten Kyoto Sushi selviytyy ostoskeskuksessa?

OpenAIRE

Van, Vo Quoc Cuong

2011-01-01

Opinnäytetyön tavoitteena on laatia liiketoimintasuunnitelma perustettavalle takeawaytyyppiselle ”Kyoto-Sushi”-ravintolalle. Ensisijaisena tavoitteena on selvittää yrityksen selviytymistä Itäkeskuksen kovassa kilpailukentässä hyvin laaditun ja realistisen liiketoimintasuunnitelman avulla. Toissijaisena tavoitteena on madaltaa ravintoloitsijaksi ryhtymisen kynnystä perehtymällä aloittavan yrittäjän vastuisiin ja velvollisuuksiin. Opinnäytetyö koostuu kolmesta osuudesta: teoreettisesta viit...

Emission trading and Kyoto's protocol: discussions concerning rules and international coordination

International Nuclear Information System (INIS)

Baron, R.

2000-01-01

The Kyoto Protocol of the Climate Convention introduced the possibility to trade greenhouse gas emission reductions among industrialized countries, as a means to reduce the total cost of achieving the agreed emission goals. The rules for this international co-ordination regime are still debated, even if its principle is generally agreed. This article, written before the negotiation in the Hague, summarizes how the notion of emission trading made its way in the Framework Convention on Climate Change. The authors show what economic gains could realistically be expected from emission trading, based on macro-economic modelling results and a simulation of trading in the conditions of the Kyoto Protocol. They stress the critical contribution that emission trading could make, provided that the Protocol's environmental basis is not undermined. In the end, the negotiation collapsed over this issue. Beyond this near-term obstacle, the international emission trading system represents a significant progress towards an efficient resolution of man-made global climate change. (author)

The Cost of Compliance: A CGE Assessment of Canada's Policy Options under the Kyoto Protocol

Energy Technology Data Exchange (ETDEWEB)

Boehringer, Christoph (Univ. of Oldenburg, Dept. of Economics, D-26111 Oldenburg (Germany)); Rutherford, Thomas F. (ETH Zuerich, Center for Energy Policy and Economy, CH-8032 Zuerich (Switzerland))

2008-07-01

Canada is committed under the Kyoto Protocol to reduce greenhouse gas emissions between 2008 and 2012 to a level six percent below the 1990 reference value. To date, however, Canada's greenhouse gas emissions remain far above 1990 levels. Stringent short-term policy measures are needed if Canada is to meet this legally binding commitment. This paper uses a multi-region, multi-commodity static general equilibrium model to quantify the economic impacts of alternative compliance strategies for Canada in the context of climate policies undertaken by other Kyoto Parties. The numerical results confirm fears among Canadian policy makers of larger economic adjustment cost should Canada fulfill its Kyoto commitment solely through domestic action. Comprehensive use of flexible mechanisms - in particular the Clean Development Mechanism - could allow Canada to live up with its international climate policy commitment at a substantially lower economic cost

Implementing the Kyoto Protocol. The role of environmental agreements

Energy Technology Data Exchange (ETDEWEB)

Torvanger, Asbjoern; Skodvin, Tora

1999-09-01

This report examines under what circumstances voluntary agreements to curb greenhouse gas emissions could be an attractive policy option from the government`s perspective. The report begins by defining the term Environmental Agreement (EA) and then explores EAs in three steps: (1) Advantages and disadvantages of EAs compared to other policy tools (direct regulation, taxes and tradable permits), based on theoretical studies and experience from practical use, (2) The potential of EAs as an international policy tool, either in a bilateral or regional setting, (3) The attractiveness of EAs to implement the Kyoto Protocol, and the relation to joint implementation and international emissions trading. The main conclusions are: (1) Experience from OECD countries suggests that EAs are most attractive as a supplement to traditional command and control, or to market-based policy tools. (2) Skillful design of EAs can improve their efficiency. (3) Bilateral EAs is an interesting policy option to regulate pollution from other countries. (4) Regional EAs are rare but could have important advantages. (5) EAs can play a role in a soft transition stage from traditional command and control to domestic emission trading, and further on to a Kyoto Protocol regime of emission trading and joint implementation. 52 refs., 2 figs., 2 tabs.

Industrial output restriction and the Kyoto protocol. An input-output approach with application to Canada

International Nuclear Information System (INIS)

Lixon, Benoit; Thomassin, Paul J.; Hamaide, Bertrand

2008-01-01

The objective of this paper is to assess the economic impacts of reducing greenhouse gas emissions by decreasing industrial output in Canada to a level that will meet the target set out in the Kyoto Protocol. The study uses an ecological-economic Input-Output model combining economic components valued in monetary terms with ecologic components - GHG emissions - expressed in physical terms. Economic and greenhouse gas emissions data for Canada are computed in the same sectoral disaggregation. Three policy scenarios are considered: the first one uses the direct emission coefficients to allocate the reduction in industrial output, while the other two use the direct plus indirect emission coefficients. In the first two scenarios, the reduction in industrial sector output is allocated uniformly across sectors while it is allocated to the 12 largest emitting industries in the last one. The estimated impacts indicate that the results vary with the different allocation methods. The third policy scenario, allocation to the 12 largest emitting sectors, is the most cost effective of the three as the impacts of the Kyoto Protocol reduces Gross Domestic Product by 3.1% compared to 24% and 8.1% in the first two scenarios. Computed economic costs should be considered as upper-bounds because the model assumes immediate adjustment to the Kyoto Protocol and because flexibility mechanisms are not incorporated. The resulting upper-bound impact of the third scenario may seem to contradict those who claim that the Kyoto Protocol would place an unbearable burden on the Canadian economy. (author)

May the Kyoto protocol produce results?

International Nuclear Information System (INIS)

Jaureguy-Naudin, M.

2009-01-01

A not well managed drastic reduction of greenhouse emissions might result in significant decrease of living standards, but without such reduction efforts, climate change might have five to twenty times higher costs. Thus, while indicating estimated consequences or evolutions of greenhouse emissions and temperature, the author stresses the need of emission reduction. She discusses the role of economic instruments which can be used in policies aimed at the struggle against climate change. She recalls the emission reduction commitments specified in the Kyoto protocol, discusses the present status, operation and results of the international emission trading scheme, the lessons learned after the first years of operation, comments the involvement of emerging countries in relationship with another mechanism defined in the protocol: the Clean Development Mechanism

No kudos for Kyoto from Imperial Oil : one company kicks at CO2 compliance, while others assume Ottawa's posturing

International Nuclear Information System (INIS)

Hope, P.

1998-01-01

Imperial Oil Ltd.'s criticisms over the high cost of complying with the carbon dioxide reduction targets set at Kyoto were discussed. Imperial Oil's document entitled 'The high cost of Kyoto' cites various independent economic-impact studies which show that Canada's commitment to lower greenhouse gas emissions to six per cent below 1990 levels by 2010 would jeopardize Canada's current prosperity and would drop the gross domestic product 3 per cent below projected growth. Several other major oil companies including Suncor share the opinion that the science on global warming is uncertain and that more research and greater public involvement is needed in the debate over the Kyoto Protocol. The oil companies are also of one mind about the need for third world countries doing their share of emission reduction. They go as far as to say that third world countries such as China and Brazil should be forced to join Canada in restricting emissions. The major oil companies operating in Canada hope that the government will consider oil industry concerns before the Kyoto Protocol is ratified. 1 fig

Is the nuclear phaseout compatible with the respect of the Kyoto protocol? The example of Belgium; La sortie du nucleaire est-elle compatible avec le respect du protocole de Kyoto? l'exemple de la Belgique

Energy Technology Data Exchange (ETDEWEB)

Berger, A

2008-12-15

This document provides data and operations needed to evaluate the impacts of the nuclear phaseout on the respect of the Kyoto protocol. The data are based on the belgium electricity production. The author concludes that the nuclear power plants shutdown will lead to a non respect of the kyoto protocol in unacceptable limits. To respect the protocol, he presents two possibilities: the today nuclear park and the use of 1600 wind turbines of 2 MW, or the improvement of the energy efficiency of the thermal power plants. (A.L.B.)

Inclined Zenith Aurora over Kyoto on 17 September 1770: Graphical Evidence of Extreme Magnetic Storm

Science.gov (United States)

Kataoka, Ryuho; Iwahashi, Kiyomi

2017-10-01

Red auroras were observed in Japan during an extreme magnetic storm that occurred on 17 September 1770. We show new evidence that the red aurora extended toward the zenith of Kyoto around midnight. The basic appearance of the historical painting of the red aurora is geometrically reproduced based on the inclination of the local magnetic field and a detailed description in a newly discovered diary. The presence of the inclined zenith aurora over Kyoto suggests that the intensity of the September 1770 magnetic storm is comparable to, or slightly larger than that of the September 1859 Carrington storm.

Efek antikaries ekstrak gambir pada tikus jantan galur wistar

Directory of Open Access Journals (Sweden)

Siti Rusdiana Puspa Dewi

2017-12-01

Full Text Available Anti-caries effect of gambier extract on male wistar rats. Several previous studies have mentioned that gambir extract can inhibit the growth of Streptococcus mutans (S. mutans because it contains active substances of catechins and tannins. The objective of this study was to explore the anti-caries effect of gambir extract on male Wistar rats. Thirty-six Wistar rats were inoculated with S. mutans, given cariogenic foods and divided into 4 groups according to the doses of gambir extract, namely 6 mg, 12 mg, 24 mg and placebo. After 60 days, the rats were euthanized, then the number of caries on the mesial or distal and occlusal surfaces was counted by using the Keyes’ method. The data were analyzed using Kruskal Wallis test. The results revealed that caries was found only in occlusal surfaces with an enamel depth. There is no significant difference among all the groups, so it can be concluded that gambir extract at 6 mg, 12 mg and 24 mg doses do not have anti-caries effect on the teeth of male Wistar rats.   ABSTRAK Beberapa penelitian terdahulu mengatakan bahwa ekstrak gambir dapat menghambat pertumbuhan Steptococcus mutans (S. mutans karena mengandung zat aktif katekin dan tanin. Tujuan dari penelitian ini adalah untuk melihat efek antikaries ekstrak gambir pada tikus jantan galur Wistar. Tiga puluh enam ekor tikus galur Wistar diinokulasi dengan S.  mutans, diberikan makanan kariogenik dan dibagi menjadi 4 kelompok, yakni, kelompok yang diberi dosis ekstrak gambir 6 mg, 12 mg, 24 mg dan plasebo. Setelah 60 hari, tikus di eutanasia, kemudian dihitung jumlah karies pada permukaan halus dan oklusal dengan menggunakan metode Keyes. Data dianalisa dengan menggunakan tes Kruskal Wallis. Hasil penelitian diketahui bahwa karies ditemukan hanya pada pemukaan oklusal dengan kedalaman email. Tidak ada perbedaan signifikan antar semua kelompok, sehingga dapat disimpulkan bahwa ekstrak gambir dengan dosis 6 mg, 12 mg dan 24 mg tidak memiliki efek

Kyoto or non-Kyoto - people or politics: results of recent public opinion surveys on energy and climate change

International Nuclear Information System (INIS)

Ashworth, Peta; Gardner, John; Littleboy, Anna

2007-01-01

Full text: We present the results of a survey of an Australian public opinion survey in the area of climate change and energy technologies and compare the results with similar studies conducted in the other major non-Kyoto-adherent party, the United States, as well as to Kyoto-adherent countries including the UK, Japan, Sweden and Spain. We explore some of the differences and similarities in attitudes and understandings. In our survey, Australians place environment, health care and petrol prices as the most important issues facing their country, while in America it is terrorism, health care and the economy and in the UK it is asylum seekers, crime and health care. In many other areas, the differences are considerably smaller and there are some remarkable similarities. Whereas climate change is increasingly cited as the leading environmental issue in most countries surveyed, in Australia, climate change is second to water availability as the top environmental concern. The study examines where climate change and energy technologies fit within these broader national and environmental priorities and identifies the general public's preferred solutions. We find clear support in Australia and the other countries surveyed for renewable energy technologies, particularly solar energy and to a lesser extent wind and biomass energy. We also find considerable disagreement in all countries regarding the future of nuclear power as well as with regard to carbon dioxide capture and storage technologies (albeit the latter with much larger uncertainty). The paper also explores the current knowledge levels of the general public in a number of countries about carbon dioxide emissions and how much as individuals, they are prepared to pay to mitigate greenhouse gas emissions. We find that, in general, at a more detailed level in terms of both attitudes and understandings of energy and climate issues there is considerable agreement across disparate countries Gudged on their national

Cooperation mechanisms of the EU renewable energy directive and flexible mechanisms of the Kyoto Protocol: comparison and lessons learnt. Working paper

Energy Technology Data Exchange (ETDEWEB)

Frieden, Dorian; Tuerk, Andreas; Steiner, Daniel

2013-07-15

This working paper discusses similarities and differences between the cooperation mechanisms of the EU renewable energy directive (RES directive) and the flexible mechanisms of the Kyoto Protocol. The cooperation mechanisms allow the (virtual) trade of renewable energy and were introduced with the RES directive to provide Member States (MS) with greater flexibility to achieve their national targets for renewable energy sources (RES). A similar kind of flexibility is known from the flexible mechanisms of the Kyoto Protocol which aim at the cost efficient achievement of emission reduction targets. Lessons learned from the Kyoto mechanisms may allow conclusions to be drawn on the design and implementation of the renewable energy cooperation mechanisms. This paper first gives an overview of the cooperation mechanisms regarding their potential, advantages and disadvantages, barriers and preconditions. This is followed by a brief explanation of and a systematic comparison with the flexible mechanisms of the Kyoto Protocol – Joint Implementation (JI); Clean Development Mechanism (CDM); and International Emissions Trading (IET). A gamut of factors influenced the success of the Kyoto mechanisms in general and in specific national contexts. Therefore, it is not possible to directly transfer past experiences with the Kyoto mechanisms to the capability of specific nations to make use of the renewable energy cooperation mechanisms. A comparison of specific features, such as the mechanism type (transfer, project-based, support scheme), price building and specific barriers can, however, help anticipate the possible dynamics and challenges of the cooperation mechanisms. Experiences with the Kyoto mechanisms show that predictions based on supply-demand analysis were valid only to a limited extent and that specific factors such as institutional capacity constraints or legal uncertainties delayed or prevented the use of the mechanisms in some cases. Similarly, for the cooperation

Driving factors of carbon dioxide emissions and the impact from Kyoto Protocol

Energy Technology Data Exchange (ETDEWEB)

Grunewald, Nicole [Goettingen Univ. (Germany). Dept. of Economics; Martinez-Zarzoso, Inmaculada [Jaume I Univ. (Spain). International Economics Institute

2009-08-15

In the last two decades increasing attention has been paid to the relationship between environmental degradation and economic development. According to the Environmental Kuznets Curve (EKC) hypothesis this relationship may be described by an inverted-U curve. However, recent evidence rejects the EKC hypothesis for GHG emissions in a broad sense. In this paper we aim to investigate whether the EKC behavior for CO2 emissions could be proved on the behalf of institutional regulations. We analyze the driving factors of CO2 for developed and developing countries to test the theory of the EKC in the context of environmental regulations using a static and dynamic panel data model. We consider the Kyoto Protocol and the Clean Development Mechanism (CDM). The results from this study indicate that the Kyoto obligations have a reducing effect on CO2 emissions in developed and developing countries. (orig.)

Kyoto and the economics of global warming; Kyoto et l'economie de l'effet de serre

Energy Technology Data Exchange (ETDEWEB)

Guesnerie, R.

2003-07-01

This report sheds light on the economic issues surrounding climate change. The objective is to fuel a longer term reflexions. The greenhouse effect raises many questions dealing with economic policy. In particular what is the right agenda for action taking into account the low reversibility of the increasing concentration of greenhouse gases? What about the Kyoto protocol architecture? How to deal with countries that will not participate in the effort for controlling emissions, while enjoying the benefits of the preservation of the climate, a collective good? How to protect the competitiveness of countries that impose environmental constraints on their producers? This report is then discussed by P. Champsaur and A. Lipietz. (A.L.B.)

Is the Kyoto Protocol an adequate environmental agreement to resolve the climate change problem?

International Nuclear Information System (INIS)

Arcas, R.L.

2001-01-01

The lack of understanding on how to handle the issue of global warming, which is embodied by the Kyoto Protocol, among the various nations of the world reached a point where environmental policy-makers saw a number of possible scenarios to global warming before the last meeting on Climate Change in July 2001 in Bonn: Amendments to the Kyoto Protocol, by changing the current targets and timetable into a long-term view of the global warming issue. The U.S. does not agree with the Kyoto Protocol Therefore, it will not do anything about it in terms of its ratification. A middle ground between the two previous options. The idea is the creation of a new mechanism where nations meet in international environmental for a voluntarily exchange of views with no legal commitments. In order to move forward, we should stop thinking of the global warming issue only in a cost-benefit analysis and instead take more into account public health and safety requirements. Since the U.S. and EU representatives may well find themselves deadlocked again when they meet at the end of October 2001 in Morocco for the next climate change convention, the author would like to make some recommendations at the end of this article. (author)

Alcohol drinking during adolescence increases consumptive responses to alcohol in adulthood in Wistar rats

Science.gov (United States)

Amodeo, Leslie R.; Kneiber, Diana; Wills, Derek N.; Ehlers, Cindy L.

2017-01-01

Binge drinking and the onset of alcohol use disorders usually peak during the transition between late adolescence and early adulthood, and early adolescent onset of alcohol consumption has been demonstrated to increase the risk for alcohol dependence in adulthood. In the present study we describe an animal model of early adolescent alcohol consumption where animals drink unsweetened and unflavored ethanol in high concentrations (20%). Using this model we investigated the influence of drinking on alcohol-related appetitive behavior and alcohol consumption levels in early adulthood. Further, we also sought to investigate whether differences in alcohol-related drinking behaviors were specific to exposure in adolescence versus exposure in adulthood. Male Wistar rats were given a 2-bottle choice between 20% ethanol and water in one group and between two water bottles in another group during their adolescence (Postnatal Day (PD) PD26-59) to model voluntary drinking in adolescent humans. As young adults (PD85), rats were trained in a paradigm that provided free access to 20% alcohol for 25 min after completing up to a fixed ratio (FR) 16-lever press response. A set of young adult male Wistar rats was exposed to the same paradigm using the same time course beginning at PD92. The results indicate that adolescent exposure to alcohol increased consumption of alcohol in adulthood. Furthermore, when investigating differences between adolescent high and low adolescent drinkers in adulthood, high consumers continued to drink more alcohol, had fewer FR failures, and had faster completion of FR schedules in adulthood whereas the low consumers were no different than controls. Rats exposed to ethanol in young adulthood also increased future intake but there were no differences in any other components of drinking behavior. Both adolescent- and adult-exposed rats did not exhibit an increase in lever pressing during the appetitive challenge session. These data indicate that adolescent

PENGARUH PEMBERIAN KEFIR BENING TERHADAP KADAR GLUKOSA DARAH PADA TIKUS WISTAR HIPERGLIKEMIA YANG DIINDUKSI STREPTOZOTOCIN (STZ

Directory of Open Access Journals (Sweden)

Judiono Judiono

2012-11-01

Full Text Available ABSTRACT Background: Hyperglycemia in diabetes caused by excessive free-radicals, which in turn increases reactive oxygen species, reduced immune function and antioxidant, the beta cell damage. Objective: To validate the effects of plain kefir probiotic on blood glucose level in streptozotocin (STZ induced hyperglycemia Wistar rats. Methods: The experiment using randomized pretest-posttest control group design was carried-out on 48 male hyperglycemia Wistar rats induced by 40 mg/kg body-weight of STZ. Rats were divided randomly into four groups: (1 negative control fed ad libitum standard diet, (2 positive control induced by STZ, (3 insulin treated 0.76 UI/200 g body weight, and (4 plain kefir 3.6 cc per day. Kefir is prepared by the use of pasteurized skim milk fermented by kefir commercial inoculums. Blood glucose was measured with Super Glucocard II meter (Arkray, Kyoto, Japan. Results Kefir supplementation 3.6 cc per day had significantly effect on blood glucose reduction after… days. Results showed that blood glucose levels before and after the treatment in each group as follows: in negative control group, before and after the treatment were 92.7 ± 6.6 mgdL and 89.4 ± 5.3 mgdL, respectively; in positive control group, before and after treatment were 263.9 ± 61.7 mgdL and 290.9 ± 99.8 mgdL; in insulin group, before and after the treatment were 286.9 ± 73.2 mgdL and 168.3 ± 53.3 mgdL; and in kefir group, before and after the treatment were 234.0 ± 61.1 mgdL and 147.8 ± 52.6 mgdL. Conclusion: Kefir supplementation significantly reduced blood glucose in vivo. Isolation and identification of probiotic involved on biomolecular and to find out the role of specific probiotic originated from kefir in diabetes mellitus are very challenging to be implemented in clinical application. [Penel Gizi Makan 2009, 32(2: 129-136] Key words: probiotic, kefir, diabetes mellitus, hyperglicemia, streptozotocin

The Kyoto Protocol and forestry practices in the United States

Science.gov (United States)

Bov B. Eav; Richard A. Birdsey; Linda S. Heath

2000-01-01

Forestry may play an important if not critical role in the ability of the U.S. to meet its greenhouse gas emissions target under the terms of the Kyoto Protocol. Given the low rate of change in the U.S. forest land area, the major anthropogenic influences on the current net forest carbon flux are forest management and protection activities that have resulted in...

Financing hydropower projects using the mechanisms provided by the Kyoto Protocol

International Nuclear Information System (INIS)

Eugenia Anca Echizli

2004-01-01

One of the most serious and current environmental global problems is the Climate Change generated by the increasing of Green House gas (GHG) level. Romania has signed the United Nation Framework Convention on Climate Change and is the first country listed in Convention Annex I which ratified Kyoto Protocol. Romania committed itself to lower the level of GHG emissions with 8% as compared with the GHG emissions level in 1989, what is similar to the commitment of EU countries. In order to satisfy the requirements of accession to the European Union, Romania has also developed several national strategies to promote sustainable development. Hidroelectrica's Environmental Policy includes international partnership to finance the hydropower projects under Kyoto Protocol of United Nation Framework Convention on Climate Change. Hidroelectrica has submitted Joint Implementation projects to the PCF program of World Bank and ERUPT programs of Dutch Government. The paper reflects Hidroelectrica's experience in that field: the actions necessary to initiate and promote such projects, the steps recommended in developing their implementation, difficulties and barriers, results obtained, learned lessons. (author)

Luther contre le protocole de Kyoto ou le retour des « indulgences ».

Directory of Open Access Journals (Sweden)

Bernard Jouve

2005-05-01

Full Text Available Le 16 février 2005 a marqué la mise en œuvre du Protocole de Kyoto. En fait, depuis l’annonce par la Russie, le 25 octobre 2004, de sa décision de ratifier ce protocole, l’affaire était entendue. Menacé depuis le refus des États-Unis, l’un des plus grands pollueurs de la planète, de ne pas le ratifier pour des raisons purement économiques alors que ce pays produit à lui seul 40 % des gaz à effet de serre ( ges , l’accord survenu à Kyoto en 1997 est enfin entériné et ...

Hepatoprotective, Antihyperlipidemic, and Anti-inflammatory Activity of Moringa oleifera in Diabetic-induced Damage in Male Wistar Rats

Science.gov (United States)

Omodanisi, Elizabeth I.; Aboua, Yapo G.; Chegou, Novel N.; Oguntibeju, Oluwafemi O.

2017-01-01

Background: The number of individuals with diabetes is increasing daily, and diabetes is presently estimated to affect about 422 million adults worldwide. Conventional drugs used to treat diabetes are not without severe side effects, accessibility, and affordability. This study elucidates the potential effects of Moringa oleifera (MO) leaves extract to manage and treat diabetes induced in male Wistar rats. Materials and Methods: Adult male Wistar rats were randomly divided into four groups (n = 12/group): NC – nondiabetic rats (positive control), MO – nondiabetic-treated rats, DM – diabetic rats (negative control), DM + MO – diabetic-treated rats. Hepatic enzymes and biochemical parameters as well as antioxidant capacity and inflammatory cytokine levels were assessed. Levels of low-density lipoprotein, high-density lipoprotein, and total cholesterol were evaluated. Results: Oral administration of methanolic extract of MO (250 mg/kg) to diabetic rats for 42 days showed a significant reduction in hepatic enzyme markers and normalized lipid profile parameters in the serum compared to normal control group. Treatment also increased the level of antioxidant capacity and alleviated inflammatory biomarkers of the liver. Histology sections of the liver tissue showed protective effect of MO in treated rats. Conclusions: MO showed hepatoprotective, anti-inflammatory, and lipid-lowering effects against streptozotocin-induced hepatotoxicity. Histological section demonstrated specific alterations in the liver of the diabetic and nondiabetic male Wistar rats while MO treatment revealed improvement in liver alterations. Abbreviations Used: IL 1: Interleukin 1, IL 6: Interleukin 16, MCP-1: Monocyte chemotactic protein, TNF-α: Tumor Necrotic factor alpha, ROS: Reactive oxygen species, MO: Moringa oleifera, STZ: Streptozotocin, SRC: Standard rat chow, ALP: Alkaline phosphatase, AST: Aspartate aminotransferase, ALT: Alanine aminotransferase, ORAC: Oxygen radical absorbance

Regional costs and benefits of alternative post-Kyoto climate regimes: Comparison of variants of the Multi-stage and Per Capita Convergence regimes

NARCIS (Netherlands)

Vuuren DP van; Elzen MGJ den; Berk MM; Lucas P; Eickhout B; Eerens H; Oostenrijk R; KMD

2003-01-01

The study documented here explores technical, economic and environmental implications of different post-Kyoto climate regimes for differentiation of future commitments that would lead to a stabilisation of greenhouse gas concentrations (Kyoto gases) in the atmosphere at 550 and 650

Analysis of kyoto university reactor physics critical experiments using NCNSRC calculation methodology

International Nuclear Information System (INIS)

Amin, E.; Hathout, A.M.; Shouman, S.

1997-01-01

The kyoto university reactor physics experiments on the university critical assembly is used to benchmark validate the NCNSRC calculations methodology. This methodology has two lines, diffusion and Monte Carlo. The diffusion line includes the codes WIMSD4 for cell calculations and the two dimensional diffusion code DIXY2 for core calculations. The transport line uses the MULTIKENO-Code vax Version. Analysis is performed for the criticality, and the temperature coefficients of reactivity (TCR) for the light water moderated and reflected cores, of the different cores utilized in the experiments. The results of both Eigen value and TCR approximately reproduced the experimental and theoretical Kyoto results. However, some conclusions are drawn about the adequacy of the standard wimsd4 library. This paper is an extension of the NCNSRC efforts to assess and validate computer tools and methods for both Et-R R-1 and Et-MMpr-2 research reactors. 7 figs., 1 tab

Zero-Carbon Energy Kyoto 2011 : Special Edition of Jointed Symposium of Kyoto University Global COE “Energy Science in the Age of Global Warming” and Ajou University BK21

CERN Document Server

2012-01-01

The nuclear plant accident at Fukushima in the wake of the Great East Japan Earthquake and tsunami has had a major impact on the energy strategy of Japan and the world. From a global perspective, approach to energy is of greater and greater consequence. The Global Center of Excellence (COE) Program of the Ministry of Education, Culture, Sports, Science and Technology of Japan, with the support of university faculty members, has established an international education and research platform to foster educators, researchers, and policy makers who can develop technologies and propose policies for establishing a CO2 zero-emission society no longer dependent on fossil fuels by the year 2100. Since 2008, a program called “Energy Science in the Age of Global Warming—Toward a CO2 Zero-Emission Energy System” has been in progress at Kyoto University. A third international symposium, titled “Zero-Carbon Energy, Kyoto 2011,” was held jointly with Ajou University, Korea, in August 2011, and this book is a compila...

Submission under the United Nations framework convention on climate change and the Kyoto protocol 2011. National inventory report for the German greenhouse gas inventory 1990-2009; Berichterstattung unter der Klimarahmenkonvention der Vereinten Nationen und dem Kyoto-Protokoll 2011. Nationaler Inventarbericht zum Deutschen Treibhausgasinventar 1990-2009

Energy Technology Data Exchange (ETDEWEB)

NONE

2011-06-15

As a Party to the United Nations Framework on Climate Change (UNFCCC), since 1994 Germany has been obliged to prepare, publish and regularly update national emission inventories of greenhouse gases. In February 2005, the Kyoto Protocol entered into force. As a result, for the first time ever the international community of nations is required to implement binding action objectives and instruments for global climate protection. As a result of Europe's own implementation of the Kyoto Protocol, via the adoption of EU Decision 280/20041, these requirements became legally binding for Germany in spring 2004. The Secretariat of the Framework Convention on Climate Change has made submission of the inventory report a pre-requisite for performance of the agreed inventory reviews. Germany now presents its ninth National Inventory Report (NIR 2011), following its inventories for the years 1990 to 2009. This latest report covers the same period (1990 to 2009), and it describes the methods and the data sources on which the calculations are based. The report and the report tables in the Common Reporting Format (CRF) have been prepared in accordance with the UNFCCC guideline on annual inventories (FCCC/SBSTA/2006/9) and, as far as possible, in accordance with the IPCC Good Practice Guidance (IPCC-GPG, 2000) and the IPCC Good Practice Guidance for Land Use, Land Use Change and Forestry (IPCC-GPG LULUCF, 2003). This year, the NIR contains, for the first time, an additional Part II, along with additional sub-chapters in the existing part, in conformance with expanded requirements under the Kyoto Protocol and the relevant decisions at the European level. Part I of the NIR presents, in Chapters 1 to 10, all the information relevant to the annual greenhouse-gas inventory. Chapter 1 provides background information about climate change and about greenhouse gas inventories, as well as further information relative to the Kyoto Protocol. Chapter 2 provides a general overview of

Submission under the United Nations framework convention on climate change and the Kyoto protocol 2011. National inventory report for the German greenhouse gas inventory 1990-2009; Berichterstattung unter der Klimarahmenkonvention der Vereinten Nationen und dem Kyoto-Protokoll 2011. Nationaler Inventarbericht zum Deutschen Treibhausgasinventar 1990-2009

Energy Technology Data Exchange (ETDEWEB)

NONE

2011-06-15

As a Party to the United Nations Framework on Climate Change (UNFCCC), since 1994 Germany has been obliged to prepare, publish and regularly update national emission inventories of greenhouse gases. In February 2005, the Kyoto Protocol entered into force. As a result, for the first time ever the international community of nations is required to implement binding action objectives and instruments for global climate protection. As a result of Europe's own implementation of the Kyoto Protocol, via the adoption of EU Decision 280/20041, these requirements became legally binding for Germany in spring 2004. The Secretariat of the Framework Convention on Climate Change has made submission of the inventory report a pre-requisite for performance of the agreed inventory reviews. Germany now presents its ninth National Inventory Report (NIR 2011), following its inventories for the years 1990 to 2009. This latest report covers the same period (1990 to 2009), and it describes the methods and the data sources on which the calculations are based. The report and the report tables in the Common Reporting Format (CRF) have been prepared in accordance with the UNFCCC guideline on annual inventories (FCCC/SBSTA/2006/9) and, as far as possible, in accordance with the IPCC Good Practice Guidance (IPCC-GPG, 2000) and the IPCC Good Practice Guidance for Land Use, Land Use Change and Forestry (IPCC-GPG LULUCF, 2003). This year, the NIR contains, for the first time, an additional Part II, along with additional sub-chapters in the existing part, in conformance with expanded requirements under the Kyoto Protocol and the relevant decisions at the European level. Part I of the NIR presents, in Chapters 1 to 10, all the information relevant to the annual greenhouse-gas inventory. Chapter 1 provides background information about climate change and about greenhouse gas inventories, as well as further information relative to the Kyoto Protocol. Chapter 2 provides a general overview of development of

An evaluation of business implications of the Kyoto Protocol

Energy Technology Data Exchange (ETDEWEB)

Torvanger, Asbjoern

2001-12-01

This report has been commissioned by Norsk Hydro ASA and written in November-December 2001. The aim of the report is to present and analyze the newest developments in the climate negotiations, particularly the seventh Conference of the Parties to the Climate Convention in Marrakech, Morocco, in October/November 2001, and to provide an evaluation of what the finalized Kyoto Protocol means for business. The report is organized as a collection of slides with supporting text explaining the background and contents of each slide. (author)

Determination of Greenhouse Gases Base Year for Hrvatska elektroprivreda (HEP) in Accordance with Kyoto Protocol

International Nuclear Information System (INIS)

Jelavic, V.; Sestic, M.; Juric, Z.; Stanic, Z.

1998-01-01

The Kyoto Protocol obliges the Republic of Croatia to reduce greenhouse gas emissions by 5 percent till the year 2010, taking a base year from the period between 1985 and 1990. Thermal power plants of Hrvatska Elektroprivreda (HEP) represent significant source of the most important greenhouse gas - CO 2 - and consequently HEP is expected to make a significant contribution to the national activities aiming to meet the Kyoto Protocol requirements. This issue is of particular importance, as Croatia has not submitted its base year to the Conference of the Parties in form of The National Communication on Climate Change, which is one of the requirements of UN Climate Change Convention and the Kyoto Protocol. Related to this, it is interesting to include emissions from the thermal power plants located in Bosnia and Herzegovina and Serbia (650 MWe) that had supplied electricity to the Croatian power supply system in the base year period and on which HEP claims legal ownership. This article presents HEP greenhouse gas emissions from the period of 1985 to 1990, as well as its contribution in total greenhouse gas emissions of Croatia. Furthermore, future HEP greenhouse gas emissions, according to its business development scenario till the year 2010, will be estimated. (author)

Access to finance for community forest management under the UNFCCC and Kyoto Protocol

NARCIS (Netherlands)

Skutsch, Margaret

2002-01-01

A previous article in ETFRN News reviewed the potential for funding for forestry under international climate agreements, particularly under the Kyoto Protocol (Skutsch, 2000). Since then, further negotiations have taken place and this article aims at giving an overview of the current situation.

Development of Taiwanese government’s climate policy after the Kyoto protocol: Applying policy network theory as an analytical framework

International Nuclear Information System (INIS)

Shyu, Chian-Woei

2014-01-01

Given its limited involvement in and recognition by international organizations, Taiwan is not presently a signatory to the United Nations Framework Convention on Climate Change (UNFCCC) or the Kyoto Protocol. The objective of this study is to analyze how and the extent to which changes in an exogenous factor, namely the Kyoto Protocol and Post-Kyoto climate negotiations, affect and ultimately lead to the formulation of and changes in the Taiwanese government's climate policy. This study applies policy network theory to examine the development of and changes in the Taiwanese government's climate policy. The results demonstrate that international climate agreements and negotiations play a key role in the development of, changes to, and transformation of Taiwan's climate policy. Scarce evidence was found in this study to demonstrate that domestic or internal factors affect climate change policy. Despite its lack of participation in the UNFCCC and the Kyoto Protocol, Taiwan has adopted national climate change strategies, action plans, and programs to reduce greenhouse gas emissions. However, these climate policies and measures are fairly passive and aim to only conform to the minimal requirements for developing countries under international climate agreements and negotiations. This process results in inconsistent and variable climate policies, targets, and regulations. - Highlights: • Taiwan is not a signatory to the UNFCCC or its Kyoto Protocol. • International climate agreements strongly affected Taiwan's climate policy. • Little evidence was found that domestic factors affect Taiwan's climate policy. • New climate policies, regulations, and laws are formulated and implemented. • Climate policies, targets, and regulations change frequently and are inconsistent

Estimation of underground structures in Kyoto city by seismic-array observations of microtremors; Bido no array kansoku ni yoru Kyoto shinai no chika kozo tansa

Energy Technology Data Exchange (ETDEWEB)

Miyakoshi, K; Kagawa, T; Akazawa, T [Osaka Soil Test, Osaka (Japan); Ogawa, Y; Shimizu, K [Osaka Gas Corp., Osaka (Japan); Ejiri, J [Obayashi Corp., Tokyo (Japan)

1997-10-22

Observations of microtremors were carried out to estimate the S-wave velocity structure by using arrays of seismographs around the Kyoto Research Park. The observation points were so arranged that equilateral triangle arrays may be formed with maximum radii at 0.2 km, 0.4 km and 0.8 km respectively with the premises of the Kyoto Research Park as the center. The seismographs have used seven vertical movement components (PELS), and were adjusted to a period of eight seconds. In addition, high-cut filters of 4 Hz were used because the observation areas are located in urban areas with heavy traffic. The analysis has used the spatial self-correlation method as a means to estimate phase velocity of surface waves contained in microtremors. As a result, phase velocity estimation has become possible for frequencies from about 0.4 Hz to 2 Hz, whereas the S-wave velocity structure was estimated to a depth of down to about 900 m by using as reference the result of the reflection method exploration having been carried out in the present areas. In addition, it was suggested that microtremors with frequencies higher than 1 Hz are in unsteady state in terms of time or space. 4 refs., 7 figs., 1 tab.

Canada and the Kyoto Protocol: Fact Sheet No. 4 - Compliance

International Nuclear Information System (INIS)

2000-11-01

The Canadian interpretation of compliance is described, emphasizing Canada's determination to work with other countries to build a clear set of rules to govern the conduct of those who participate in these new international instruments and international markets. The Canadian view is that a compliance regime that will facilitate compliance and offers countries significant incentives to take their commitments seriously is critical in providing the legal certainty for the Kyoto mechanisms to work

Kyoto commitments: CHP will help the UK

International Nuclear Information System (INIS)

Knowles, Michael

1998-01-01

In order to meet the United Kingdom's targets for carbon dioxide emissions reduction, agreed at the Kyoto Summit, the UK Government is promoting the use of combined heat and power (CHP) plants. Such schemes need to offer over 70% efficiency, have on-site or nearby heat uses, and allow flexibility for the export of electricity where this is appropriate. Electricity trading arrangements will need to be re-organised in line with similar commodities, in order to facilitate and promote the growth of CHP and renewable energy schemes. Financial incentives and regulation of electricity prices will also contribute to the promotion of CHP schemes, ultimately leading to reduced CO 2 pollution as a result of the growth in the UK's CHP capacity. (UK)

Evaluation of climate policy in the Netherlands 2005. On the way to Kyoto

International Nuclear Information System (INIS)

Bonney, M.

2005-01-01

An evaluation of climate policy in the Netherlands aimed at the realization of targets as formulated in the Kyoto Protocol. The Dutch target is to reduce the emission of greenhouse gases by 6% for the period 2008-2012, compared to the emission in 1990 [nl

Implementation of the Kyoto protocol

International Nuclear Information System (INIS)

2006-07-01

The Rio Earth summit in 1992 has been the starting point of an international awareness about the global risk of climatic change. At this occasion, the richest countries committed themselves to stabilize their greenhouse gas emissions and to reach by the year 2000 an emissions level equivalent to the one of 1990. The Kyoto protocol in 1997 has permitted to convert this will into juridically constraining quantitative commitments. In 2005, Russia ratified the protocol while in 2001 the USA refused to do so. Because the commitments signed are ambitious, flexibility mechanisms have been implemented: 'emission permits' (emissions trading), 'joint implementation' allowing the investments abroad for greenhouse gases abatement in another developed country, and 'clean development mechanisms' when investments are made in a developing country. The Marrakech conference of December 2001 has permitted to fix up the eligibility criteria of projects belonging to the joint implementation and clean development mechanisms. The effective implementation of these mechanisms still raises technical difficulties to evaluate and measure the effective abatement of greenhouse gas emissions. (J.S.)

Kyoto Protocol: Debate on environment and development in the discussions on Climate Change

International Nuclear Information System (INIS)

Rodriguez S, Liliana

2007-01-01

The climatic behavior of the planet and its consequences has favored debates about the models of development of the countries responsible for the accelerated deterioration of the atmosphere and of the natural phenomena by these recurrent days. Nevertheless, countries as United States, after signing commitments as the Convention on Climatic Change, refuse to acquire the obligations of the Kyoto Protocol, from fear of undergoing deterioration in their economies. In this setting, where the nation responsible for the emission of approximately 36% of the turned out effect greenhouse gases result of the human action in the planet does not commit itself to adopt restrictive policies to make its models of production but friendly with the nature although these measures begin to be imposed to other nations as determining factors in the international commercial negotiations, seems to be that the adoption of the Kyoto Protocol for developing countries as Colombia is not absolutely beneficial

Genetically determined differences in the resistance to myocardial infarction in Wistar and August rats.

Science.gov (United States)

Belkina, L M; Saltykova, V A; Pshennikova, M G

2001-06-01

In intact August rats, the cardiac contractile function at rest was by 76% higher than in Wistar rats, while their hearts, both intact and after acute myocardial infarction, were more resistant to isometric load than the hearts of Wistar rats. Postinfarction mortality in August rats was 18% vs. 70% in Wistar rats. Adrenoreactivity of the myocardium in August rats was decreased compared to that in Wistar rats. These peculiarities can determine high resistance of August rats to myocardial infarction.

Submission under the United Nations framework convention on climate change and the Kyoto protocol 2012. National inventory report for the German greenhouse gas inventory 1990-2010; Berichterstattung unter der Klimarahmenkonvention der Vereinten Nationen und dem Kyoto-Protokoll 2012. Nationaler Inventarbericht zum Deutschen Treibhausgasinventar 1990-2010

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-06-15

All Parties listed in ANNEX I of the UNFCCC are required to prepare and submit annual National Inventory Reports (NIRs) containing detailed and complete information on the entire process of preparation of greenhouse gas inventories. The purpose of such reports is to ensure the transparency, consistency and comparability of inventories and support the independent review process. Pursuant to decision 15/CMP.1, as of 2010 all of the countries listed in ANNEX I of the UN Framework Convention on Climate Change that are also parties to the Kyoto Protocol must submit annual inventories in order to be able to make use of flexible mechanisms pursuant to Articles 6, 12 and 17 of the Kyoto Protocol. Together with the inventory tables, Germany submits a NIR, which refers to the period covered by the inventory tables and describes the methods and data sources on which the pertinent calculations are based. The report and the report tables in the Common Reporting Format (CRF) have been prepared in accordance with the UNFCCC guideline on annual inventories (FCCC/SBSTA/2006/9) and in accordance with the IPCC Good Practice Guidance (IPCC-GPG, 2000) and the IPCC Good Practice Guidance for Land Use, Land-Use Change and Forestry (IPCC-GPG LULUCF, 2003). The NIR contains a Part II, along with additional sub-chapters, that fulfill the expanded requirements under the Kyoto Protocol and the relevant obligations at the European level. Part I of the NIR presents, in Chapters 1 to 10, all the information relevant to the annual greenhouse-gas inventory. Chapter 1 provides background information about climate change and about greenhouse-gas inventories, as well as further information relative to the Kyoto Protocol. This section describes the National System pursuant to Article 5.1 of the Kyoto Protocol, which system is designed to aid and assure compliance with all reporting obligations with respect to atmospheric emissions and removals in sinks. In addition, this chapter describes the basic

Submission under the United Nations framework convention on climate change and the Kyoto protocol 2012. National inventory report for the German greenhouse gas inventory 1990-2010; Berichterstattung unter der Klimarahmenkonvention der Vereinten Nationen und dem Kyoto-Protokoll 2012. Nationaler Inventarbericht zum Deutschen Treibhausgasinventar 1990-2010

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-06-15

All Parties listed in ANNEX I of the UNFCCC are required to prepare and submit annual National Inventory Reports (NIRs) containing detailed and complete information on the entire process of preparation of greenhouse gas inventories. The purpose of such reports is to ensure the transparency, consistency and comparability of inventories and support the independent review process. Pursuant to decision 15/CMP.1, as of 2010 all of the countries listed in ANNEX I of the UN Framework Convention on Climate Change that are also parties to the Kyoto Protocol must submit annual inventories in order to be able to make use of flexible mechanisms pursuant to Articles 6, 12 and 17 of the Kyoto Protocol. Together with the inventory tables, Germany submits a NIR, which refers to the period covered by the inventory tables and describes the methods and data sources on which the pertinent calculations are based. The report and the report tables in the Common Reporting Format (CRF) have been prepared in accordance with the UNFCCC guideline on annual inventories (FCCC/SBSTA/2006/9) and in accordance with the IPCC Good Practice Guidance (IPCC-GPG, 2000) and the IPCC Good Practice Guidance for Land Use, Land-Use Change and Forestry (IPCC-GPG LULUCF, 2003). The NIR contains a Part II, along with additional sub-chapters, that fulfill the expanded requirements under the Kyoto Protocol and the relevant obligations at the European level. Part I of the NIR presents, in Chapters 1 to 10, all the information relevant to the annual greenhouse-gas inventory. Chapter 1 provides background information about climate change and about greenhouse-gas inventories, as well as further information relative to the Kyoto Protocol. This section describes the National System pursuant to Article 5.1 of the Kyoto Protocol, which system is designed to aid and assure compliance with all reporting obligations with respect to atmospheric emissions and removals in sinks. In addition, this chapter describes the basic

Stressed lungs: unveiling the role of circulating stress hormones in ozone-induced lung injury and inflammation

Science.gov (United States)

Our recent work demonstrated that circulating stress hormones, epinephrine and corticosterone/cortisol, are involved in mediating ozone pulmonary effects through the activation of hypothalamus-pituitary-adrenal (HPA) axis. Adrenalectomy in Wistar Kyoto (WKY) rats diminished circu...

Chronic effects of soft drink consumption on the health state of Wistar rats: A biochemical, genetic and histopathological study

OpenAIRE

ALKHEDAIDE, ADEL; SOLIMAN, MOHAMED MOHAMED; SALAH-ELDIN, ALAA-ELDIN; ISMAIL, TAMER AHMED; ALSHEHIRI, ZAFER SAAD; ATTIA, HOSSAM FOUAD

2016-01-01

The present study was performed to examine the effects of chronic soft drink consumption (SDC) on oxidative stress, biochemical alterations, gene biomarkers and histopathology of bone, liver and kidney. Free drinking water of adult male Wistar rats was substituted with three different soft drinks: Coca-Cola, Pepsi and 7-Up, for three consecutive months. The serum and organs were collected for examining the biochemical parameters associated with bone, liver and kidney functions. Semi-quantitat...

Kyoto, coal and sharing the cost burden

International Nuclear Information System (INIS)

Daley, J.

1998-01-01

Parties to the UN Framework Convention on Climate Change (the Rio Treaty) at their first conference in 1995 agreed that the commitments entered into under the Convention were 'not adequate' to achieve its objective. These nations determined to proceed to strengthen those commitments under a protocol to be prepared for the third conference at Kyoto. Also it was to contain 'quantified emissions limitation objectives' (binding targets) on the industrial countries. For such targets to be consistent with Australia's interests, they would need to recognise Australia's relatively fast population and economic growth (both of which imply relatively faster growth in emissions), the increasing preponderance of energy intensive industries in the Australian economy, and our dependence on the export of energy intensive manufactures (like aluminium and other metals) and direct export of fossil fuels (including coal and natural gas). Major parties to the protocol negotiations - the USA and the EU - were advocates of uniform percentage emissions reductions from 1990 levels. Uniform percentage reductions, however intuitively appealing, impose widely different costs on different parties on account of their different circumstances. Australia would have been penalised by uniform reductions because our projected business-as-usual emissions trajectory is relatively steep, and measures adopted internationally to mitigate greenhouse gas emissions impact disproportionately on this economy (notably on account of reduced demand for Australian coal). The accompanying charts depict ABAREs 'less stringent' emissions scenario - addressing a goal of stabilising industrial countries' emissions of C0 2 rather than reducing them. ABARE's simulation for Australia by sector shows big negative impacts on output of non-ferrous metals, iron and steel, and coal. The metals industries, directly or indirectly are the coal industry's most important domestic customers. It is argued that because of the impact

A comparative study on the energy policies in Japan and Malaysia in fulfilling their nations' obligations towards the Kyoto Protocol

International Nuclear Information System (INIS)

Lau, Lee Chung; Tan, Kok Tat; Lee, Keat Teong; Mohamed, Abdul Rahman

2009-01-01

Global warming and the associated changes in the world climate pattern have been accepted world wide as the gravest threat to humanity in the 20th century. To mitigate the impacts of global warming, the Kyoto Protocol was established in 1997 with the objective of reducing global greenhouse gases (GHGs) emission, in particular carbon dioxide (CO 2 ), by 5.2% below 1990 levels. Developed nations that ratified the Protocol are committed to GHG reduction targets while developing nations are encouraged to reduce GHG emissions on a voluntary basis. Since most of the GHGs emissions come from the energy sector, energy policy plays an important role in fulfilling the Kyoto Protocol obligations. This year marks the beginning of the commitment period for the 2012 Kyoto Protocol. In this case, it would be worthwhile to compare the energy policies in Malaysia and Japan as these nations move towards fulfilling their obligations towards the Kyoto Protocol; bearing in mind that both countries ratified the Protocol, but that Japan commits a reduction target of 6% while Malaysia bears no obligation. Based on the comparison, recommendations were made on how a developing nation like Malaysia could adopt the policies implemented in Japan to suit local conditions and contribute significantly to GHG reduction.

Management of radioactive liquid and solid wastes at the Research Reactor Institute, Kyoto University, (3)

International Nuclear Information System (INIS)

Tsutsui, Tenson; Shimoura, K.; Koyama, A.

1977-11-01

In this report, the management of radioactive liquid and solid wastes at the Research Reactor Institute, Kyoto University during past 6 years, from April in 1971 to March in 1977 are reviewed. (auth.)

Kyoto Protocol implementation in Serbia as precognition of sustainable energetic and economic development

International Nuclear Information System (INIS)

Golusin, Mirjana; Munitlak Ivanovic, Olja

2011-01-01

The paper gives reasons for low energy efficiency typical of the Serbian economy, which is based on outdated and dirty technologies. The comparison of selected economic indicators and indicators of energy efficiency in both Serbia and the European Union points out the benefits of the Kyoto Protocol implementation due to the growth of competitiveness in the global market. Serbia has no obligation to reduce GHG emissions, the authors point to the proposals whose implementation along with the mechanisms of the Protocol can enable Serbia the access to markets that trade GHG emissions and the access to dedicated funds, self-financing or attracting foreign investments to raise energy efficiency, which will be accompanied by adequate economic benefits. A similar principle can be applied in all countries that are not obliged to reduce GHG emissions. The application of different mechanisms aiming to increase energy efficiency in Serbia, could contribute to the increase of GDP annual growth rate from 5% to 7%, which cannot be achieved by any other economic instrument. Energy efficiency, which is actually a question of competitiveness of each economy, can finance itself through the mechanisms of the Kyoto Protocol by selling excess emissions resulting from improved energy efficiency. - Research highlights: → Serbia is a country with the outdated technology and low energy efficiency values. → Sustainable economic and energetic growth can be stirred by inserting Kyoto Protocol. → By investing in modern technology Serbia could lessen emission into the atmosphere. → Cut of emission in the atmosphere could help reaching certain carbon credit values. → By selling the carbon credit Serbia could do economic growth of 5-7% on a year level.

Meteor observation by the Kyoto meteor radar

International Nuclear Information System (INIS)

Kato, S.; Tsuda, T.

1987-01-01

The Kyoto Meteor Radar is a monostatic coherent pulsed Doppler radar operating on the frequency of 31.57 MH. The system is computer controlled and uses radio interferometry for echo height determination. The antenna, an improvement, can be directed either to the north or the east. The system has been continuously collecting data on winds at meteor heights by radar observation. The meteor echo rate was also measured, the echo rate distribution with height and the daily variation in height integrated echo rate are discussed. Investigations of atmospheric tides are being pursued by cooperative observations. A novel approach to the study of gravity waves was attempted using the meteor radar which is able to detect the horizontal propagation of the waves by observing the changing phase through the region illuminated by the radar

WW instituudi direktor Christopher Flavin : Kyoto protokoll viiakse ellu Bushita / Christopher Flavin ; interv. Tarmo Virki

Index Scriptorium Estoniae

Flavin, Christopher

2002-01-01

World Watch Instituudi direktor leiab, et maailm vajaks globaalset keskkonnaorganisatsiooni, mis tasakaalustaks Maailma Kaubandusorganisatsiooni mõju. Euroopa Liit ja Jaapan suudavad Kyoto protokolli ratifitseerimise ellu viia ka ilma USA-ta. Lisa: Tuumaenergia pole lahendus

The road from Kyoto : A U.S. industry view

Energy Technology Data Exchange (ETDEWEB)

O`Keefe, W.F. [American Petroleum Inst., Washington, DC (United States)

1998-05-01

An American industry perspective of the Kyoto Protocol and its ability to produce a viable solution to global warming was offered. The Protocol would require most industrialized nations (including Canada and the United States) to cut their carbon dioxide emissions by 6 to 8 per cent below 1990 levels by year 2008 to 2012. Developing countries would not have to meet this target. It was argued that this set of targets and timetables assumes that climate risks are known with great certainty, when in fact, the long term risks of climate change are highly uncertain and near-term risks are small. It was also argued that developing countries account for more than half of the growth in CO{sub 2} emissions, therefore, their exemption from the Kyoto Protocol would make the Protocol ineffective against even a moderate warming scenario. Furthermore, the Protocol has the potential to create reactionary incentives for energy-intensive industries to move their facilities and jobs to countries without the curbs on CO{sub 2} emissions. It was suggested that a better climate policy would include all countries in CO{sub 2} reductions. It would be less expensive to achieve a target CO{sub 2} atmospheric concentration by curbing emissions slowly at first, developing technology to do so more cheaply and moving more aggressively in later years. The reality is that if the climate policy is too expensive, it is less practical and more difficult to achieve, both economically and politically. 1 tab., 2 figs.

Flexible mechanisms in the corporate greenhouse: implementation of the Kyoto Protocol and the globalization of the electric power industry

Energy Technology Data Exchange (ETDEWEB)

Schreuder, Y.; Sherry, C. [University of Delaware, Newark, DE (United States). Center for Energy and Environmental Policy

2001-07-01

The contradictions and unresolved tensions between economic globalization and climate change negotiations have added urgency to the climate change debate. The paper argues that the declining role of the nation state in the global economy and the increasing reach of transnational corporations throughout the world present a serious challenge to the environmental integrity and success of international environmental treaties such as the Kyoto Protocol. In particular efficacy and equity of the flexible mechanism under the Kyoto Protocol are questioned as illustrated by the patterns of Foreign Direct Investment (FDI) of the US electric power industry in the developing world. US FDI in the electric power sectors of developing countries supports continued carbon-intensive development patterns which will make the long-term goals of the Kyoto Protocol more difficult to achieve. Consequently, FDI raises questions about justifiability of giving credit to Annex I countries through CDM projects undertaken by transnational electric power corporations. 13 refs.

Kyoto global consensus report on Helicobacter pylori gastritis.

Science.gov (United States)

Sugano, Kentaro; Tack, Jan; Kuipers, Ernst J; Graham, David Y; El-Omar, Emad M; Miura, Soichiro; Haruma, Ken; Asaka, Masahiro; Uemura, Naomi; Malfertheiner, Peter

2015-09-01

To present results of the Kyoto Global Consensus Meeting, which was convened to develop global consensus on (1) classification of chronic gastritis and duodenitis, (2) clinical distinction of dyspepsia caused by Helicobacter pylori from functional dyspepsia, (3) appropriate diagnostic assessment of gastritis and (4) when, whom and how to treat H. pylori gastritis. Twenty-three clinical questions addressing the above-mentioned four domains were drafted for which expert panels were asked to formulate relevant statements. A Delphi method using an anonymous electronic system was adopted to develop the consensus, the level of which was predefined as ≥80%. Final modifications of clinical questions and consensus were achieved at the face-to-face meeting in Kyoto. All 24 statements for 22 clinical questions after extensive modifications and omission of one clinical question were achieved with a consensus level of >80%. To better organise classification of gastritis and duodenitis based on aetiology, a new classification of gastritis and duodenitis is recommended for the 11th international classification. A new category of H. pylori-associated dyspepsia together with a diagnostic algorithm was proposed. The adoption of grading systems for gastric cancer risk stratification, and modern image-enhancing endoscopy for the diagnosis of gastritis, were recommended. Treatment to eradicate H. pylori infection before preneoplastic changes develop, if feasible, was recommended to minimise the risk of more serious complications of the infection. A global consensus for gastritis was developed for the first time, which will be the basis for an international classification system and for further research on the subject. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Annual report of Radiation Laboratory Department of Nuclear Engineering Kyoto University for fiscal 1993

International Nuclear Information System (INIS)

1994-07-01

This publication is the collection of the papers presented research activities of Radiation Laboratory, Department of Nuclear Engineering, Kyoto University during the 1993 academic/fiscal year (April, 1993 - March, 1994). The 47 of the presented papers are indexed individually. (J.P.N.)

Annual report of Radiation Laboratory Department of Nuclear Engineering Faculty of Engineering, Kyoto University

International Nuclear Information System (INIS)

1993-07-01

This publication is the collection of the papers presented research activities of Radiation laboratory, Department of Nuclear Engineering, Kyoto University during the 1992 academic/fiscal year (April, 1992 - March, 1993). The 48 of the presented papers are indexed individually. (J.P.N.)

Carbon emissions: the economic benefits of the Kyoto Protocol

International Nuclear Information System (INIS)

Leo, G.A. de; Gatto, M.

2001-01-01

The third Conference of the Parties in Kyoto set the target of reducing greenhouse-gas emissions by an average of 5.3 per cent with respect to 1990 values by 2008 - 2012. One of the main objections to the protocol's ratification is that compliance would pose an unbearable economic burden on the countries involved. But we show here that this is not the case if costs apart from the direct costs of energy production are also considered. Costs are also incurred in rectifying damage to human health, material goods, agriculture and the environment related to greenhouse-gas emissions. (author)

UCN-VCN facility and experiments in Kyoto University Reactor

International Nuclear Information System (INIS)

Kawabata, Yuji; Okumura, Kiyoshi; Utsuro, Masahiko

1993-01-01

An ultracold and very cold neutron facility was installed in Kyoto University Reactor (KUR). The facility consists of a very cold neutron (VCN) guide tube, a VCN bender, a supermirror neutron turbine and experimental equipments with ultracold neutrons (UCN). The properties of each equipments are presented. UCN is generated by a supermirror neutron turbine combined with the cold neutron source operated with liquid deuterium, and the UCN output spectrum was measured by the time-of-flight method. A gravity analyzer for high resolution spectroscopy and a neutron bottle for decay experiments are now developing as the UCN research in KUR. (author)

Post-Kyoto energy consumption strategies for the Greek interconnected electric system

International Nuclear Information System (INIS)

Dagoumas, A.S.; Panapakidis, I.P.; Papagiannis, G.K.; Dokopoulos, P.S.

2008-01-01

The liberalization of the Greek electric market (Law 2773/99, updated with Laws 3175/2003 and 3426/2005 for incorporating Directive 2003/54 into the Greek legislation) is in its final structural transformation, which includes the fact that from 1.7.2007 each customer can select its electricity provider. This new status together with the procedure towards the formation of a post-Kyoto plan, raise the need of examining different energy saving strategies in the consumption side for evaluating their economic and environmental consequences. Such strategies may be useful for the decision makers or the electricity retail companies. This paper examines the influence of several post-Kyoto electricity consumption strategies in the Greek interconnected electric system for the period 2005-2025. The aim of the paper is to be used as a decision makers' tool for investigating the potential of electricity consumption policies. The results show that policies related either to seasonal peak demand control, or targeting at the total electric consumption lead to significant gains and emission reduction. Moreover the influence of factors, such as the weather conditions, the discount rate of the energy investments, the fuel prices evolution and the consumers' behavior linkage with oil prices are examined

Parties at the convention of the United Nations on climatic change and second meeting of the parties to the Kyoto protocol; Parties a la convention-cadre des Nations-Unies sur les changements climatiques et seconde reunion des parties au Protocole de Kyoto

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-07-01

Kenya hosted the second meeting of the Parties to the Kyoto Protocol in conjunction with the twelfth session of the conference of the Parties to the climatic change convention, in Nairobi from 6 to 17 November 2006. This document presents in a first part the key areas discussed at Nairobi; in a second part the international framework with the consequences of the Kyoto protocol implementation; and in the last part the demonstrable progresses of the France in the policy effects, tendencies concerning the greenhouse gases and the respect of the commitments. (A.L.B.)

An assessment of the economic and environmental implications for Canada of the Kyoto Protocol

International Nuclear Information System (INIS)

2000-11-01

The National Climate Change Process was launched in April 1998 to examine the feasibility and implications of Canada's commitment to the Kyoto Protocol. The Analysis Modelling Group (AMG) was designated to assess the economic and environmental consequences for Canada in achieving the target. This report summarizes the analytical approach, the assumptions, the results and the main findings of the AMG's efforts to analyse the macro-/micro-economic, social, health and environmental implications of the Kyoto Protocol. The role of the AMG was to provide policymakers with guidance on some issues such as the economic implications of different broad policy approaches, the potential costs of greater access to the Kyoto flexibility mechanisms, the sectoral and regional distributions of emissions reductions, and the degree to which Canada's competitive position could be affected by the achievement of the Protocol. The relative importance of greenhouse gas reduction was also discussed along with a review of actions that offer significant potential for emissions reductions. The AMG examined five policy packages or Paths which are differentiated by different degrees of reliance on specific measures and tradable permit systems and by the imposition of sectoral versus national targets. It was concluded that at the national level, attainment of the target results in sustained, long-term negative economic impacts. In the long run, the reduction in gross domestic product (GDP) relative to the business-as-usual case, ranges from 0 to 3 per cent depending on the path-scenario combination. It was emphasized that it is important to provide perspective on these estimates. 37 refs., 64 figs

Sürdürülebilir Kalkınma İçin Türkiye’de Düşük Karbon Ekonomisi ve Kyoto Protokolü’nün Finansman Kaynakları / Low Carbon Economy and Financial Sources of The Kyoto Protocol for Sustainable Development In Turkey

Directory of Open Access Journals (Sweden)

Mehmet Ragıp BAYRAK

2012-12-01

Full Text Available Dünya kamuoyu bugünlerde uluslararası iklim değişimi rejiminin, sera gazlarının salımına kısıtlamalar getiren Kyoto Protokolü’nün sona ereceği 2012 yılı sonrasını ve emisyon azaltımı adına net hedefler ortaya koymayan Kopenhag Uzlaşması’nın sonuçlarını tartışmaktadır. Düşük karbon ekonomisi modelinin temellerini oluşturan ve serbest piyasa ekonomisi mekanizması içerisinde çözüm arayan Temiz Kalkınma Mekanizması (CDM, Ortak Uygulama (JI ve Emisyon Ticareti (ET gibi Kyoto Protokolü uygulamalarının 2012 sonrasındaki durumu da belirsizdir. Kyoto Protokolü, iklim değişimi ile mücadelenin ve düşük karbon ekonomisine geçişin yollarını devlet müdahaleciliğinden çok serbest piyasa ekonomisi mekanizması içerisinde aramaktadır ve sorunun global boyutuna vurgu yapmaktadır. Sürdürülebilir ekonomik kalkınma sürecinin sağlıklı bir şekilde geliştirilmesi ve yürütülmesi gelişmekte olan ülkeler arasında yer alan Türkiye için de önem arz etmektedir ancak ülkemizin bu konuda yeterli gelişmeyi gösterdiği söylenemez. Bu çalışmada Kyoto Protokolü’nün piyasa temelli finansman kaynakları incelenmiş ve Türkiye’de düşük karbon ekonomisi modeline geçiş sürecinin durumu ve bu süreçte ilgili finansman kaynaklarının yeri araştırılmıştır. Ayrıca iklim değişikliği rejiminin 2012 yılında sona erecek ilk yükümlülük dönemi sonrası alacağı şekle ilişkin işleyen süreçte gelişmekte olan ülkelerin de emisyon indiriminden sorumlu tutulması gerektiğine ve bu yolla karbon piyasalarında işlem hacminin artması gerektiği sonucuna ulaşılmıştır. Low Carbon Economy and Financial Sources of The Kyoto Protocol for Sustainable Development In Turkey The World public opinion currently discusses uncertainty of the Post - Kyoto negotiations because The Copenhagen Summit held to talk about Post-Kyoto period on December 2009 still has no clear targets

Nuclear power for greenhouse gas mitigation under the Kyoto protocol: The Clean Development Mechanism (CDM)

International Nuclear Information System (INIS)

Rogner, H.-H.

2000-01-01

At the 43rd regular session of the IAEA General Conference, Member States requested the IAEA to help countries in assessing nuclear power's role in light of global environmental challenges and energy needs. Such assistance should include support for implementing national case studies, and facilitating access to relevant information about nuclear power's role in achieving sustainable development in developing countries and in mitigating GHG emissions. The dissemination of information on CDM is of particular importance to developing countries, so as to enable Member States interested in the mechanism to take an active and informed role in the debate regarding the Kyoto Protocol and eligible CDM technologies. Therefore, the Secretariat organized a series of information seminars, workshops and training courses for Member States on the Kyoto Protocol, the Clean Development Mechanism, Joint Implementation and Emissions Trading with particular emphasis on the potential role of nuclear power for GHG mitigation. On request, the Secretariat also provided training and assistance to several Member States in the preparation of national case studies that explore the potential role of nuclear power as a CDM technology. These case studies will be presented by the respective national study teams during this side event at the 44th IAEA General Conference. Within the general criteria included in the Kyoto Protocol, the decision on which technologies are eligible for GHG mitigation under the flexibility mechanisms is a sovereign decision of each country

Blood Pressure Interventions Affect Acute and Four-Week Diesel Exhaust Induced Pulmonary Injury in Healthy and Hypertensive Rats

Science.gov (United States)

Rationale: We recently showed that inhalation exposure of normotensive Wistar Kyoto (WKY) rats to whole diesel exhaust (DE) elicits changes in cardiac gene expression that broadly mimics expression in spontaneously hypertensive (SH) rats without DE. We hypothesized that pharmacol...

SYSTEMIC IMBALANCE OF ESSENTIAL METALS AND CARDIAC GENE EXPRESSION IN RATS FOLLOWING ACUTE PULMONARY ZINC EXPOSURE

Science.gov (United States)

We have recently demonstrated that PM containing water-soluble zinc may cause cardiac injury following pulmonary exposure. To investigate if pulmonary zinc exposure causes systemic metal imbalance and direct cardiac effects, we intratracheally (IT) instilled male Wistar Kyoto (WK...

Kyoto and beyond : A plan of action to meet and exceed Manitoba's Kyoto targets

International Nuclear Information System (INIS)

2002-10-01

This document represents the next step in Manitoba's effort to mitigate the effects of climate change. A message from the Manitoba Premier and the Minister of Conservation of Manitoba are included in the introduction. The Action Plan is based in part on the discussion among climate experts and public input gathered in the course of the 2001 task force and the 2001 public forum on climate change. A rise in average global temperatures is affecting most of the planet, which is due in part to the upsetting of the balance of greenhouse gases in the atmosphere as a result of human activities. It is affecting weather patterns, water, agriculture, forests, health and welfare, and life in the North. The Manitoba government is committed to meeting and exceeding the reduction targets set under the Kyoto Protocol through renewable electricity, Selkirk conversion, ethanol, methane capture, and other measures targeted toward industry. Energy efficiency also plays a big part in the process of reducing greenhouse gas emissions. The government is leading by example, and also investing in knowledge. It is promoting technology development and innovation while enhancing awareness and understanding. All sectors are being encouraged to implement appropriate measures. The various initiatives undertaken by each department and organization under each of those headings are described. figs

Climate economics: post-Kyoto tracks; Economie du climat: pistes pour l'apres-Kyoto

Energy Technology Data Exchange (ETDEWEB)

Godard, Olivier; Ponssard, Jean-Pierre [Laboratoire d' Econometrie, Ecole Polytechnique, Route de Saclay, 91128 Palaiseau (France)

2011-03-19

Commitments obtained by the Kyoto protocol will end in 2012. An impressive series of conferences - Bali (2007), Copenhagen (2009), Cancun (2010) to mention the main ones - were organised to prepare the post-2012 regime. Everything was supposed to be decided at the Copenhagen meeting but the state representatives came up against the obstacle. The pre-Copenhagen hope has given place to disillusion and has led to a turn-off towards a weekly coordinated regime which requires a strategic revision of approaches. This book presents the lessons learnt from the relative failure of these negotiations and proposes new paths for the future. It puts forward some strategic stakes that have to be taken into account for the future: the equity between very heterogeneous countries and populations, the industrial competitiveness, the carbon leaks and the violation of the most ambitious climate policies due to the heterogeneity of commitment levels, and the geopolitical reality. The world will have to live for a long time with heterogeneous carbon prices, themselves reflecting heterogeneous commitment levels. New modalities have to be defined which would manage to combine justice and efficiency. Two complementary paths are developed in this book: the establishing of adjustment mechanisms at borders and of international sectoral agreements. (J.S.)

Ocean iron fertilization in the context of the Kyoto protocol and the post-Kyoto process

International Nuclear Information System (INIS)

Bertram, Christine

2010-01-01

Ocean iron fertilization is currently discussed as a potential measure to mitigate climate change by enhancing oceanic CO 2 uptake. Its mitigation potential is not yet well explored, and carbon offsets generated through iron fertilization activities could currently not be traded on regulated carbon markets. Still, commercial interests in ocean iron fertilization already exist, which underlines the need to investigate a possible regulatory framework for it. To this end, I first discuss important basic aspects of ocean iron fertilization, namely its scientific background, quantitative potential, side effects, and costs. In a second step, I review regulatory aspects connected to ocean iron fertilization, like its legal status and open access issues. Moreover, I analyze how the regulations for afforestation and reforestation activities within the framework of the Kyoto Clean Development Mechanism (CDM) could be applied to ocean iron fertilization. Main findings are that the quantitative potential of ocean iron fertilization is limited, that costs are higher than initially hoped, and that potential adverse side effects are severe. Moreover, the legal status of ocean iron fertilization is currently not well defined, open access might cause inefficiencies, and the CDM regulations could not be easily applied to ocean iron fertilization.

Data base of reactor physics experimental results in Kyoto University critical assembly experimental facilities

International Nuclear Information System (INIS)

Ichihara, Chihiro; Fujine, Shigenori; Hayashi, Masatoshi

1986-01-01

The Kyoto University critical assembly experimental facilities belong to the Kyoto University Research Reactor Institute, and are the versatile critical assembly constructed for experimentally studying reactor physics and reactor engineering. The facilities are those for common utilization by universities in whole Japan. During more than ten years since the initial criticality in 1974, various experiments on reactor physics and reactor engineering have been carried out using many experimental facilities such as two solidmoderated cores, a light water-moderated core and a neutron generator. The kinds of the experiment carried out were diverse, and to find out the required data from them is very troublesome, accordingly it has become necessary to make a data base which can be processed by a computer with the data accumulated during the past more than ten years. The outline of the data base, the data base CAEX using personal computers, the data base supported by a large computer and so on are reported. (Kako, I.)

Options for the second commitment period of the Kyoto Protocol

Energy Technology Data Exchange (ETDEWEB)

Hoehne, Niklas; Phylipsen, Dian; Ullrich, Simone; Blok, Kornelis

2005-02-15

This study assesses available options for the second commitment period of the Kyoto Protocol. The study includes the following sections: An introduction, an overview of proposals and establishing a network, analysis of interests of countries, selected country case studies, an overview of the issues to be considered, options for adaptation to climate change, a new approach ''Common but Differentiated Convergence'', an update of the Triptych approach, a comprehensive compromise proposal, the comparison of emission allowances under various approaches and a negotiation strategy for the EU and Germany. (orig.)

Options for the second commitment period of the Kyoto Protocol

Energy Technology Data Exchange (ETDEWEB)

Hoehne, Niklas; Phylipsen, Dian; Ullrich, Simone; Blok, Kornelis

2005-02-15

This study assesses available options for the second commitment period of the Kyoto Protocol. The study includes the following sections: An introduction, an overview of proposals and establishing a network, analysis of interests of countries, selected country case studies, an overview of the issues to be considered, options for adaptation to climate change, a new approach ''Common but Differentiated Convergence'', an update of the Triptych approach, a comprehensive compromise proposal, the comparison of emission allowances under various approaches and a negotiation strategy for the EU and Germany. (orig.)

Streptozotocin-induced diabetes mellitus in spontaneously hypertensive rats: a pathophysiological model for the combined effects of hypertension and diabetes

NARCIS (Netherlands)

Pijl, A. J.; van der Wal, A. C.; Mathy, M. J.; Kam, K. L.; Hendriks, M. G.; Pfaffendorf, M.; van Zwieten, P. A.

1994-01-01

The present study was undertaken to investigate the combined effects of hypertension and streptozotocin-induced diabetes mellitus in the rat. Accordingly, four groups of rats were studied: Wistar Kyoto rats (WKY), diabetic WKY, spontaneously hypertensive rats (SHR) and diabetic SHR, respectively.

Stevia preferences in Wistar rats.

Science.gov (United States)

Núñez Martínez, Paula; Argüelles Luis, Juan; Perillán Méndez, Carmen

2016-11-01

The Stevia rebaudiana plant is likely to become a major source of high-potency sweetener for the growing natural-food market. S. rebaudiana is the source of a number of sweet diterpenoid glycosides, but the major sweet constituents are rebaudioside A and stevioside. These two constituents have similar pharmacokinetic and metabolic profiles in rats and humans, and thus, studies carried out with either steviol glycoside are relevant to both. Other studies illustrate the diversity of voluntary sweet intake in mammals. This study was done using a series of two-bottle tests that compared a wide range of sweetener concentrations versus saccharin concentrations and versus water. Wistar rats displayed preferences for stevia extract and pure rebaudioside A solutions over water at a range of concentrations (0.001% to 0.3%), and their intake peak occurred at 0.1% concentration. They also preferred solutions prepared with a commercial rebaudioside A plus erythritol mixture to water, and their peak was at 2% concentration. The present study provides new information about the responses of Wistar rats to stevia compounds and commercial stevia products such as Truvia. These results could help with the appropriate dosage selection for focused behavioral and physiological studies on stevia.

How the negotiators tackled the 'hot air' issue for the second commitment period of the Kyoto Protocol

International Nuclear Information System (INIS)

2013-02-01

In 1997, when the Kyoto Protocol was approved, developed countries set their greenhouse gas (GHG) reduction commitments in relation to a 'base year' level. For the Kyoto Protocol, the year 1990 was chosen in most cases. However, irrespective of GHG mitigation action, the countries of the former Soviet Union have seen their emissions of greenhouse gases significantly decreasing after the collapse of the USSR. Given that their emissions were and still are today far below the commitments they established in 1997, these countries have a significant surplus of allowances referred to as 'hot air'. Before the COP 18 that took place in Doha (Qatar) late 2012, many countries and observers raised concern about this 'hot air'. Typically, there were two separate questions: What should we do with the accumulated surplus from the first commitment period of the Kyoto Protocol (CP1)? And will a new 'hot air' be created during the second commitment period (CP2)? This analysis explores the implications of the decisions made in Doha, using the case of Ukraine to illustrate responses to the questions raised. Indeed, as the European Union regulation forbids European countries to use CP1 units to achieve CP2 targets, Ukraine is the principal country committing to CP2 with a substantial reserve of CP1 units

Denmark's climate policy objectives and achievements. Report on demonstrable progress in 2005 under the Kyoto Protocol

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-07-01

This report is about Denmark's demonstrable progress made under the Kyoto Protocol. The report has been prepared according to the guidelines for reporting under the United Nations Framework Convention on Climate Change and the Kyoto Protocol. The report has been prepared on the basis of Denmark's Fourth National Communication on Climate Change under the United Nations Framework Convention on Climate Change. The Fourth National Communication is the first National Communication after the Kyoto Protocol entered into force. Compared to the Third National Communication, the Fourth National Communication is extended with supplementary information in accordance with the additional reporting requirements for parties to the Protocol. Since the information in the Fourth National Communication corresponds to a great extent to the information that must be included in this report, Denmark has chosen to prepare the two reports in parallel. Except information on Greenland and a few updates the present report contains the same information as the progress report published and forwarded to the European Commission in June 2005. The present report will be forwarded to the UN Climate Secretariat together with the Fourth National Communication whereto references for further information are made. (au)

Short-Term Therapy with Rosiglitazone, a PPAR-γ Agonist, Improves Metabolic Profile and Vascular Function in Nonobese Lean Wistar Rats

OpenAIRE

Naderali, Mohammad M.; Itua, Imose; Abubakari, Abdul-Razak; Naderali, Ebrahim K.

2012-01-01

A number of preclinical and clinical studies have reported blood-pressure-lowering benefits of thiazolidinediones in diabetic subjects and animal models of diabetes. This study was designed to further elucidate vascular effects of rosiglitazone, on healthy nonobese, lean animals. Adult male Wistar rats were randomized and assigned to control and rosiglitazone-treated groups and were dosed daily with either vehicle or rosiglitazone (10 mg kg−1 day−1) by oral gavage for 5 days. Compared with co...

Implementing the Kyoto protocol : why JI and CDM show more promise than international emissions trading

NARCIS (Netherlands)

Woerdman, E.

The Kyoto protocol allows developed countries to achieve cost-effective greenhouse gas emission reductions abroad by means of international emissions trading (IET), joint implementation (JI) and the clean development mechanism (CDM). The article argues that JI and CDM projects will be more

Maternal separation diminishes α-adrenergic receptor density and function in renal vasculature from male Wistar-Kyoto rats.

Science.gov (United States)

Loria, Analia S; Osborn, Jeffrey L

2017-07-01

Adult rats exposed to maternal separation (MatSep) are normotensive but display lower glomerular filtration rate and increased renal neuroadrenergic drive. The aim of this study was to determine the renal α-adrenergic receptor density and the renal vascular responsiveness to adrenergic stimulation in male rats exposed to MatSep. In addition, baroreflex sensitivity was assessed to determine a component of neural control of the vasculature. Using tissue collected from 4-mo-old MatSep and control rats, α 1 -adrenergic receptors (α 1 -ARs) were measured in renal cortex and isolated renal vasculature using receptor binding assay, and the α-AR subtype gene expression was determined by RT-PCR. Renal cortical α 1 -AR density was similar between MatSep and control tissues (B max = 44 ± 1 vs. 42 ± 2 fmol/mg protein, respectively); however, MatSep reduced α 1 -AR density in renal vasculature (B max = 47 ± 4 vs. 62 ± 4 fmol/mg protein, P adrenergic receptor expression and function in the renal vasculature could develop secondary to MatSep-induced overactivation of the renal neuroadrenergic tone. Copyright © 2017 the American Physiological Society.

Will OPEC lose from the Kyoto Protocol?

International Nuclear Information System (INIS)

Barnett, Jon; Dessai, Suraje; Webber, Michael

2004-01-01

A range of energy-economy models forecast losses to members of the Organisation of Petroleum Exporting Countries (OPEC) should the Kyoto Protocol come into force. These forecasts are a powerful influence in the United Nations Framework Convention on Climate Change negotiations. They are used by OPEC to advance the agenda on the impacts of response measures, covertly arguing for compensation for lost oil revenues arising from implementation of the Protocol. This paper discusses this issue, and explores the key assumptions of these models and their uncertainties. Assumptions about carbon leakage, future availability of oil reserves, substitution, innovation, and capital turnover are considered. The paper suggests that losses will not affect OPEC countries equally, and that these losses are not likely to be as substantial as the models forecast. A range of policy measures are proposed to lessen any impact the Protocol may have on OPEC

World CO_2-energy emissions balance and impacts of the Kyoto Protocol in Europe

International Nuclear Information System (INIS)

Chateau, Bertrand

2005-01-01

CO_2 represents more than 80% of all GHG emissions and it is increasing since 1990. Energy accounts for 85% of all GHG emissions. The United States account for almost 50% of all GHG emissions from the countries of the Annex B. Russian emissions have collapsed, from 22% to 13% of total emissions from Annex B countries between 1990 and 2002. The share of the United States has increased by 6 points since 1990, the EU-15's by one point. Germany, United Kingdom, France, Italy and Spain cover 75% of total GHG emissions from the EU-15 (2002). CO_2-energy emissions in the world: 26.3 GtCO_2 in 2003. Annex B's countries account for around 60% of the world emissions; Annex B's countries which have ratified the Kyoto Protocol represent around one third of all emissions; China accounts for 16% of total emissions. China, CEI, USA and the EU-25 drive world emissions in 2003: Chinese emissions have risen by from 12% between 2002 and 2003, they account for one third of the world emissions increase. Chinese emissions have increased as much as all Annex B's countries, 25% of the world emissions increase come from the Annex B's countries which have ratified the Kyoto Protocol. CO_2-energy Emissions from the annex B's countries have been steady between 1990 and 2003: The annex B's countries which have ratified Kyoto have decreased by 10% in 2003 compared to 1990; US emissions increased sharply when those of the EU-25 decreased: +20% versus -5%; The 'hot air' of the CIS still represents 28% of 1990 CIS emissions; Meanwhile, the weight of China and India has dramatically increased: +73% and 82%. Coal is the principal emission source in the world in 2003. Since 1990, the emissions increase is principally due to coal. The energy sector (power generation essentially) accounts for more than half of total CO_2-energy emissions; the transport sector is the second largest emitter (20%). 3/4 of the CO_2-energy emissions increase is due to the energy sector, 1/4 due to the transport sector. The

GHG emissions, GDP growth and the Kyoto Protocol: A revisit of Environmental Kuznets Curve hypothesis

Energy Technology Data Exchange (ETDEWEB)

Huang, Wei Ming; Lee, Grace W.M. [Graduate Institute of Environmental Engineering, National Taiwan University, 71, Chou-Shan Road, Taipei 106 (China); Wu, Chih Cheng [Energy and Air Pollution Control Section, New Materials R and D Department, China Steel Corporation, 1, Chung-Kang Road, Siaogang District, Kaohsiung 81233 (China)

2008-01-15

The Kyoto Protocol attempts through political negotiations to guide participating industrialized countries' greenhouse gas (GHG) emissions from a positive growing trend, to reach a peak point (or turning point), and then be reduced to a negative growth. That means the relationship between decreasing GHG emissions and economic growth may be described by an inverted-U curve (or called a bell-shaped curve), which is consistent with the concept of the Environmental Kuznets Curve (EKC) hypothesis. This research observed that the economic development and GHG emissions in Economies in Transition (EITs) exhibit a hockey-stick curve trend (or called quasi-L-shape curve), that also generates a lot of 'hot air' which is significant to the implementation of the Kyoto Protocol. In addition, through the analysis of single-country time series data and GDP data, this research demonstrated that statistical data for most of the Annex II countries do not possess evidence that supports the EKC hypothesis for GHG emissions. The results from this study also indicated that the 38 industrialized countries are unable to meet their targets under the Kyoto Protocol within the specified time period, which are probably caused by the econometric method's inability to predict accurately the extents and development of innovative technologies and Clean Development Mechanism (CDM) projects. If the international community truly wants to reduce the GHG emissions, the effectiveness of the existing international framework for emissions reduction needs to be reconsidered seriously, and the global cooperation mechanism also needs to be greatly enhanced. (author)

GHG emissions, GDP growth and the Kyoto Protocol: A revisit of Environmental Kuznets Curve hypothesis

Energy Technology Data Exchange (ETDEWEB)

Huang Weiming [Graduate Institute of Environmental Engineering, National Taiwan University, 71, Chou-Shan Road, Taipei 106, Taiwan (China); Lee, Grace W.M. [Graduate Institute of Environmental Engineering, National Taiwan University, 71, Chou-Shan Road, Taipei 106, Taiwan (China)], E-mail: gracelee@ntu.edu.tw; Wu Chihcheng [Energy and Air Pollution Control Section, New Materials R and D Department, China Steel Corporation, 1, Chung-Kang Road, Siaogang District, Kaohsiung 81233, Taiwan (China)

2008-01-15

The Kyoto Protocol attempts through political negotiations to guide participating industrialized countries' greenhouse gas (GHG) emissions from a positive growing trend, to reach a peak point (or turning point), and then be reduced to a negative growth. That means the relationship between decreasing GHG emissions and economic growth may be described by an inverted-U curve (or called a bell-shaped curve), which is consistent with the concept of the Environmental Kuznets Curve (EKC) hypothesis. This research observed that the economic development and GHG emissions in Economies in Transition (EITs) exhibit a hockey-stick curve trend (or called quasi-L-shape curve), that also generates a lot of 'hot air' which is significant to the implementation of the Kyoto Protocol. In addition, through the analysis of single-country time series data and GDP data, this research demonstrated that statistical data for most of the Annex II countries do not possess evidence that supports the EKC hypothesis for GHG emissions. The results from this study also indicated that the 38 industrialized countries are unable to meet their targets under the Kyoto Protocol within the specified time period, which are probably caused by the econometric method's inability to predict accurately the extents and development of innovative technologies and Clean Development Mechanism (CDM) projects. If the international community truly wants to reduce the GHG emissions, the effectiveness of the existing international framework for emissions reduction needs to be reconsidered seriously, and the global cooperation mechanism also needs to be greatly enhanced.

GHG emissions, GDP growth and the Kyoto Protocol: A revisit of Environmental Kuznets Curve hypothesis

International Nuclear Information System (INIS)

Huang Weiming; Lee, Grace W.M.; Wu Chihcheng

2008-01-01

The Kyoto Protocol attempts through political negotiations to guide participating industrialized countries' greenhouse gas (GHG) emissions from a positive growing trend, to reach a peak point (or turning point), and then be reduced to a negative growth. That means the relationship between decreasing GHG emissions and economic growth may be described by an inverted-U curve (or called a bell-shaped curve), which is consistent with the concept of the Environmental Kuznets Curve (EKC) hypothesis. This research observed that the economic development and GHG emissions in Economies in Transition (EITs) exhibit a hockey-stick curve trend (or called quasi-L-shape curve), that also generates a lot of 'hot air' which is significant to the implementation of the Kyoto Protocol. In addition, through the analysis of single-country time series data and GDP data, this research demonstrated that statistical data for most of the Annex II countries do not possess evidence that supports the EKC hypothesis for GHG emissions. The results from this study also indicated that the 38 industrialized countries are unable to meet their targets under the Kyoto Protocol within the specified time period, which are probably caused by the econometric method's inability to predict accurately the extents and development of innovative technologies and Clean Development Mechanism (CDM) projects. If the international community truly wants to reduce the GHG emissions, the effectiveness of the existing international framework for emissions reduction needs to be reconsidered seriously, and the global cooperation mechanism also needs to be greatly enhanced

Hypertension impairs postnatal vasculogenesis role of antihypertensive agents

NARCIS (Netherlands)

D. You (Dong); C. Cochain (Clément); C. Loinard (Céline); J. Vilar (Jose Manuel); B.M.E. Mees (Barend); M. Duriez (Micheline); B.I. Levy (Bernard); J.S. Silvestre (Jean Sebastien)

2008-01-01

textabstractWe analyzed the effect of hypertension on postischemic vasculogenesis. Ischemia was induced by right femoral artery ligature in Wistar Kyoto rats (WKY) or spontaneously hypertensive rats (SHR) treated with or without angiotensin-converting enzyme inhibitor (Perindopril, 0.76 mg/kg/d) and

Increased transient receptor potential canonical type 3 channels in vasculature from hypertensive rats

DEFF Research Database (Denmark)

Liu, Daoyan; Yang, Dachun; He, Hongbo

2009-01-01

We tested the hypothesis that transient receptor potential canonical type 3 (TRPC3) channels are increased in vascular smooth muscle cells and aortic tissue from spontaneously hypertensive rats (SHR) compared with normotensive Wistar Kyoto rats. Expression of TRPC3 was analyzed by immunohistochem...

[Reference curves for assessing the physical growth of male Wistar rats].

Science.gov (United States)

Cossio-Bolaños, Marco; Gómez Campos, Rossana; Vargas Vitoria, Rodrigo; Hochmuller Fogaça, Rosalvo Tadeu; de Arruda, Miguel

2013-11-01

Wistar rats are one of the most popular strains routinely used for research in the laboratory to serve as an important research tool, so it requires strict control of variables such as age, sex and body weight, and Thus to extrapolate the results to the human model. To develop reference curves for assessing the physical growth of male Wistar rats according to chronological age and somatic maturation from a non-invasive. The subjects studied were 731 male Wistar rats transversely. We assessed age, body weight and body surface. LMS method was used to construct percentile curves based on weight and somatic maturation. The proposed physical growth curves are used to track the physical growth and nutritional status diagnosis of male Wistar rats. Budgets by cutting points are: P3, P10, P25, P50, P75, P90 and P97. The results suggest that scientists from different areas can use such references, in order to extrapolate somatic growth phases of the laboratory rat and the human model is a non-invasive alternative to assess growth and nutritional status. Copyright AULA MEDICA EDICIONES 2013. Published by AULA MEDICA. All rights reserved.

Climate economics: post-Kyoto tracks

International Nuclear Information System (INIS)

Godard, Olivier; Ponssard, Jean-Pierre

2011-01-01

Commitments obtained by the Kyoto protocol will end in 2012. An impressive series of conferences - Bali (2007), Copenhagen (2009), Cancun (2010) to mention the main ones - were organised to prepare the post-2012 regime. Everything was supposed to be decided at the Copenhagen meeting but the state representatives came up against the obstacle. The pre-Copenhagen hope has given place to disillusion and has led to a turn-off towards a weekly coordinated regime which requires a strategic revision of approaches. This book presents the lessons learnt from the relative failure of these negotiations and proposes new paths for the future. It puts forward some strategic stakes that have to be taken into account for the future: the equity between very heterogeneous countries and populations, the industrial competitiveness, the carbon leaks and the violation of the most ambitious climate policies due to the heterogeneity of commitment levels, and the geopolitical reality. The world will have to live for a long time with heterogeneous carbon prices, themselves reflecting heterogeneous commitment levels. New modalities have to be defined which would manage to combine justice and efficiency. Two complementary paths are developed in this book: the establishing of adjustment mechanisms at borders and of international sectoral agreements. (J.S.)

Increased Energy Efficiency in Slovenian Industry - A Contribution to the Kyoto Target

International Nuclear Information System (INIS)

Selan, B.; Urbancic, A.

1998-01-01

In Slovenia the actual fast growth of greenhouse emissions will require substantial efforts to fulfil the target set in Kyoto. The end-use emissions in the in the industrial sectors represented one third of the total CO 2 emissions in the country in 1996. The cost-effective potential in the sector for CO 2 emission reduction is significant. In the paper, the most important ongoing energy efficiency activities in the industrial sector are presented: information and awareness building, energy advising to larger industrial consumers, energy audition programme, demonstration programme of energy efficiency technologies, financial incentives for energy efficiency investment and the energy efficiency investment fund. A CO 2 tax has been in force since 1997. The results of an evaluation of energy efficiency strategies in industry in the frame of the project 'Integrated resource planning for the energy efficiency in Slovenia' are discussed from the viewpoint of greenhouse gases reduction targets set by Slovenia, and a brief information on the ongoing and expected post Kyoto activities and studies is given. The most important points of the future GHG reduction strategy related to industrial sector in Slovenia will be focused on intensified energy efficiency programme, increased combined heat and power production (CHP), and the effects of incentives through the CO 2 tax. (author)

Developmental stress elicits preference for methamphetamine in the spontaneously hypertensive rat model of attention-deficit/hyperactivity disorder.

Science.gov (United States)

Womersley, Jacqueline S; Mpeta, Bafokeng; Dimatelis, Jacqueline J; Kellaway, Lauriston A; Stein, Dan J; Russell, Vivienne A

2016-06-17

Developmental stress has been hypothesised to interact with genetic predisposition to increase the risk of developing substance use disorders. Here we have investigated the effects of maternal separation-induced developmental stress using a behavioural proxy of methamphetamine preference in an animal model of attention-deficit/hyperactivity disorder, the spontaneously hypertensive rat, versus Wistar Kyoto and Sprague-Dawley comparator strains. Analysis of results obtained using a conditioned place preference paradigm revealed a significant strain × stress interaction with maternal separation inducing preference for the methamphetamine-associated compartment in spontaneously hypertensive rats. Maternal separation increased behavioural sensitization to the locomotor-stimulatory effects of methamphetamine in both spontaneously hypertensive and Sprague-Dawley strains but not in Wistar Kyoto rats. Our findings indicate that developmental stress in a genetic rat model of attention-deficit/hyperactivity disorder may foster a vulnerability to the development of substance use disorders.

Ethanol during adolescence decreased the BDNF levels in the hippocampus in adult male Wistar rats, but did not alter aggressive and anxiety-like behaviors

Directory of Open Access Journals (Sweden)

Letícia Scheidt

2015-09-01

Full Text Available Objective:To investigate the effects of ethanol exposure in adolescent rats during adulthood by assesssing aggression and anxiety-like behaviors and measuring the levels of inflammatory markers.Methods:Groups of male Wistar rats (mean weight 81.4 g, n = 36 were housed in groups of four until postnatal day (PND 60. From PNDs 30 to 46, rats received one of three treatments: 3 g/kg of ethanol (15% w/v, orally, n = 16, 1.5 g/kg of ethanol (12.5% w/v, PO, n = 12, or water (n = 12 every 48 hours. Animals were assessed for aggressive behavior (resident x intruder test and anxiety-like behaviors (elevated plus maze during adulthood.Results:Animals that received low doses of alcohol showed reduced levels of brain-derived neurotrophic factor (BDNF in the hippocampus as compared to the control group. No significant difference was found in prefrontal cortex.Conclusions:Intermittent exposure to alcohol during adolescence is associated with lower levels of BDNF in the hippocampus, probably due the episodic administration of alcohol, but alcohol use did not alter the level agression toward a male intruder or anxiety-like behaviors during the adult phase.

Soil respiration and its role in Russia's terrestrial C flux balance for the Kyoto baseline year

International Nuclear Information System (INIS)

Stolbovoi, Vladimir

2003-01-01

This study introduces a transparent, operational model of estimating soil respiration (SR) to meet the requirements of the Kyoto Protocol of the United Nation Framework Convention on Climate Change within a framework of full carbon accounting (Nilsson et al.; 2000). By applying this model, we are able to define SR for the Kyoto 1990 baseline year for Russia (3200 Tg C), and establish soil emission thresholds for any spatial units, e.g. vegetation zones and land-use patterns. This model is built upon a fundamental biogeochemical cycle and provides a scientific basis for carbon management. SR comprised about 74% of the photosynthetically assimilated carbon in 1990, with the remainder accounted for in several areas. The carbon flux balance is, therefore, found to be closed for Russia. Our findings suggest that incomplete accounting is the reason for missing carbon globally

Kyoto protocol and related issues; Chikyu ondanka boshi Kyoto kaigi (COP3) to sono kadai

Energy Technology Data Exchange (ETDEWEB)

Ninomiya, Y. [Global Industrial Social Progress Research Institute, Tokyo (Japan)

1997-09-30

The Third Session of the Conference of the Parties to the United Nations Framework Convention on Climate Change (COP3) will be held in Kyoto in December 1997. Described herein are the current status and issues of the convention. USA and Japan, which hold important keys to set up the abatement target, have issued no proposals concretely at the current AGBM (Ad-hoc Group Berlin Mandate) 7, and the conference for the concrete targets will be decided in the next AGBM 8 to be held in October. The final target will be set by the ministerial segment of COP3, because the negotiations for the treaty are political in nature. USA proposes reduction at a uniform, realistic rate, and Japan proposes reduction at a uniform rate or setting up the emission target per capita, each being different from reduction at a much higher uniform rate proposed by EU. Within EU, however, 10% out of 15% reduction rate it proposes is agreed by the member countries, and the remaining rate of % may not be agreed. It is necessary for the advanced parties to set up realistic and legally binding solutions, including ratification by USA, which can persuade the developing countries. tab.1

Kyoto Protocol, constraint or opportunity for coal based electricity producers

International Nuclear Information System (INIS)

Balasoiu, Constantin; Alecu, Sorin

2006-01-01

Coming into force of Kyoto Protocol (KP) in February 2005, as a result of its signing by Russian Federation, created the lawfulness of its provisions and mechanisms in order to reduce the average emission of Greenhouse Gases (GHG) at a global level down to 5.2 %. Passing this environment problem from a constrained area (regulations, directives) to an opportunity area (business) created the possibility that the achievement of KP objectives to be not an exclusive financial task of 'polluting actors', but opened the opportunity of bringing on stage all the necessary elements of a modern business environment: banks, investments from founds companies, consultants, buyers, sellers, stocks exchange. Until now, the investments and emissions transactions based by KP mechanisms at the worldwide level was focused on renewable energy area. Because for the most of countries, including Romania, the production of electricity based on fossil fuels (special coal) is one of the main option, bringing the KP mechanisms in operation in this area is difficult for at least two reasons: - the investments are huge; - the emissions reduction is not spectacular. In these circumstances, this paper gives an overview of the present GHG emission market, transaction mechanisms on this market and of the ways through which coal based electricity producers from Romania can access this market. We consider that the filtration of the information in this area from electricity producer point of view makes the content of this paper a good start for a new approach of environment management and its conversion from constraint (financial resources consumer) to opportunity ( financial resources producer). The paper contains are as follows: 1. Kyoto Protocol at a glance; 2. Emission trading mechanisms; 2.1. Transaction mechanisms under KP; 2.1.1. Joint Implementation (JI); 2.1.2 Clean Development Mechanism (CDM); 2.1.3. Emissions Trading (ET); 2.2. Other transactions mechanisms; 2.2.1. European Union Emissions

EV car sharing/rental pilot project in Kyoto : an outline of the project

Energy Technology Data Exchange (ETDEWEB)

Kitamura, R. [Kyoto Univ., (Japan). Dept. of Civil Engineering Systems; Masunaga, K. [Japan Electric Vehicle Association, Minato, Tokyo (Japan)

2000-07-01

This paper presented a demonstration project in the City of Kyoto, Japan, which is aimed at determining if a Public Car System is an economically viable option for the twenty first century. The Kyoto electric vehicle (EV) car sharing project comprises advanced systems for EV reservation, check-out and return, and fleet operation and management. The most unique feature of this project is that it utilizes the ever expanding Internet and advanced mobile phones with Internet capabilities. Initially, 35 two-seater EVs will be shared by employees and visitors for business-related trips on weekdays and by tourists on weekends. The car sharing will be only short-term for only a single trip. The EV can be checked out and returned to any service depot located at railroad stations, major business centers and tourist attractions for user convenience. The ultimate goal of the project is to promote energy and resource conservation while providing adequate levels of mobility for people. Converting existing fleets to EVs which produce no exhaust gases is considered to be a viable solution to the problem of air pollution caused by traffic jams. tabs., figs.

Augmented vascular smooth muscle cell stiffness and adhesion when hypertension is superimposed on aging.

Science.gov (United States)

Sehgel, Nancy L; Sun, Zhe; Hong, Zhongkui; Hunter, William C; Hill, Michael A; Vatner, Dorothy E; Vatner, Stephen F; Meininger, Gerald A

2015-02-01

Hypertension and aging are both recognized to increase aortic stiffness, but their interactions are not completely understood. Most previous studies have attributed increased aortic stiffness to changes in extracellular matrix proteins that alter the mechanical properties of the vascular wall. Alternatively, we hypothesized that a significant component of increased vascular stiffness in hypertension is due to changes in the mechanical and adhesive properties of vascular smooth muscle cells, and that aging would augment the contribution from vascular smooth muscle cells when compared with the extracellular matrix. Accordingly, we studied aortic stiffness in young (16-week-old) and old (64-week-old) spontaneously hypertensive rats and Wistar-Kyoto wild-type controls. Systolic and pulse pressures were significantly increased in young spontaneously hypertensive rats when compared with young Wistar-Kyoto rats, and these continued to rise in old spontaneously hypertensive rats when compared with age-matched controls. Excised aortic ring segments exhibited significantly greater elastic moduli in both young and old spontaneously hypertensive rats versus Wistar-Kyoto rats. were isolated from the thoracic aorta, and stiffness and adhesion to fibronectin were measured by atomic force microscopy. Hypertension increased both vascular smooth muscle cell stiffness and vascular smooth muscle cell adhesion, and these increases were both augmented with aging. By contrast, hypertension did not affect histological measures of aortic collagen and elastin, which were predominantly changed by aging. These findings support the concept that stiffness and adhesive properties of vascular smooth muscle cells are novel mechanisms contributing to the increased aortic stiffness occurring with hypertension superimposed on aging. © 2014 American Heart Association, Inc.

The Long Road from Ljubljana to Kyoto: Implementing Emission Trading Mechanisms and CO2 Tax

Directory of Open Access Journals (Sweden)

Tanja Markovič-Hribernik

2006-03-01

Full Text Available According to the Kyoto Protocol, Slovenia is required to reduce GHG emissions to an average of 8% below base year 1986 emissions in the period 2008-2012. Slovenia established different measures for reducing GHG emissions long before its ratification. It was first transition country who implemented CO2 tax in the 1997. Several changes in CO2 tax have not brought the desired results. CO2 emissions have actually increased. At the beginning of 2005, Slovenia joined other EU member states by implementing the emissions trading instrument, defined by new EU Directive. At the same time, Slovenia has adopted a new CO2 tax system, which is compatible with the new circumstances. The main purpose of this paper is to present the characteristics of Slovenian approach to national allocation plan for emissions trading and analyze the problems of the CO2 tax in Slovenia. Paper also describes the compliance cost of achieving the Kyoto target and expected movements on the Slovenian allowances market.

In vitro uptake of 75Se-selenite by lens of young and adult rats

International Nuclear Information System (INIS)

Sladkova, J.; Ostadalova, I.; Babicky, A.; Obenberger, J.

1988-01-01

The uptake was observed of 75 Se-selenite by the lens in Wistar strain rats in adult animals, in 17-day old rats kept with their mothers and in prematurely weaned rats. Also measured was the excretion of 75 Se by the lens of young and adult rats following incubation in the medium with radioselenium. The metabolites were analysed which were discharged by the lens containing 75 Se. In Brattleboro rats the uptake of 75 Se-selenite was also measured by the lens in young and adult rats. The uptake of 75 Se-selenite by the lens in young Wistar rats was found to be 1.6 times higher than by the lens of adult rats and the time course of the radioselenium uptake was slightly different. In the lens of prematurely weaned rats no significant difference was found in the uptake of radioselenium after 4 hours as compared with rats of the same age kept with their mothers. In homozygous Brattleboro rats, a higher uptake of 75 Se-selenite was found as compared with both young and adult heterozygous rats. The time course and the quantity of 75 Se efflux from the lens of young and adult Wistar rats differed significantly after 0.5 hour of pre-incubation. From metabolites containing 75 Se excreted by the lens following preincubation, glutathione selenotrisulfide and a not yet accurately determined fraction with a large share of radioactivity were isolated. The stated results provide yet more proof that selenium cataract is a manifestation of the ontogenic dependence of selenium metabolism in the lens and in the entire organism. (author). 4 tabs., 30 refs

Parties at the convention of the United Nations on climatic change and second meeting of the parties to the Kyoto protocol

International Nuclear Information System (INIS)

2006-01-01

Kenya hosted the second meeting of the Parties to the Kyoto Protocol in conjunction with the twelfth session of the conference of the Parties to the climatic change convention, in Nairobi from 6 to 17 November 2006. This document presents in a first part the key areas discussed at Nairobi; in a second part the international framework with the consequences of the Kyoto protocol implementation; and in the last part the demonstrable progresses of the France in the policy effects, tendencies concerning the greenhouse gases and the respect of the commitments. (A.L.B.)

On the quality of compliance mechanisms in the Kyoto Protocol

International Nuclear Information System (INIS)

Nentjes, Andries; Klaassen, Ger

2004-01-01

In this paper we evaluate the compliance mechanisms in the Kyoto Protocol as agreed at the seventh Conference of Parties to the United Nations Framework Convention on Climate Change (UNFCCC) in Marrakech. We differ from the literature since we concentrate on the complete set of compliance rules agreed in Marrakech and, as a new element, we systematically discuss these compliance incentives in conjunction with the implicit compliance incentives: reputation protection, emission trading and banking. We conclude that effectiveness and efficiency go hand in hand for all explicit and implicit compliance incentives except one--emission trading. Trading improves efficiency but this can also occur at the cost of increasing non-compliance

Interleukin-1 beta inhibits rat thyroid cell function in vivo and in vitro by an NO-independent mechanism and induces hypothyroidism and accelerated thyroiditis in diabetes-prone BB rats

DEFF Research Database (Denmark)

Reimers, J I; Rasmussen, A K; Karlsen, A E

1996-01-01

Interleukin-1 beta has been implicated as a pathogenic factor in the development of autoimmune thyroiditis. When given for 5 days to normal non-diabetes-prone Wistar Kyoto rats, it decreased plasma concentrations of total tri-iodothyronine and thyroxine and increased plasma TSH. These effects were...

Etude Climat no. 43 'Use of Kyoto credits by European installations: from an efficient market to a burst bubble'

International Nuclear Information System (INIS)

Stephan, Nicolas; Bellassen, Valentin; Alberola, Emilie

2014-01-01

Among the publications of CDC Climat Research, 'Climate Reports' offer in-depth analyses on a given subject. This issue addresses the following points: During the Phase II of the European Trading Scheme, installations had the option to surrender carbon credits from project-based mechanisms of the Kyoto Protocol (CERs and ERUs). The rules set by Member States and approved by the European Commission capped the demand at around 1,400 MtCO 2 between 2008 and 2012. In the end, over 1 billion Kyoto credits (675 million CERs and 383 million ERUs) have been surrendered by EU ETS installations. What conclusions can be drawn from this unique experience in a CO 2 allowance market?

Land Use: the Kyoto protocol, the FAO definition of forest and the Italian Inventory of Forests and Carbon Stocks

Directory of Open Access Journals (Sweden)

2005-01-01

Full Text Available In 2000, after the international agreement on the Kyoto Protocol of the United Nations Framework Convention on Climate Change, the United Nation Food and Agriculture Organization decided to adopt a new set of basic forest and forest change definitions. The main change is that new definitions are no more related to land cover but to land use. The entry into force of the Kyoto Protocol requires now that national forest related data must be based on land use concept. Thus, national forest inventory shall be designed in order to collect data which are consistent with current land-use related definitions. In this paper the authors analyze the case of the Italian forest inventory.

Effect of one session endurance exhausting exercise on some coagulation markers of mature and immature wistar rats

Directory of Open Access Journals (Sweden)

Shadmehr MirdarHarijani

2013-06-01

Full Text Available Background: The incidence of thrombosis is lower in children and prepubertal period than adults. But its incidence increases in adolescence.The aim of this study was comparing the effect of one session of endurance exhaustive exercise in different times on some of coagulation systems markers in pre and after maturation wistar rats. Material and Methods: 27mature male wistar rats with 241±5 grams mean weight and 27 immature male rats with 97±5 grams mean weight which were 14 and 5 weeks old, respectively, after two weeks getting accustomed to the new environment and treadmill, were divided into one control and two exercising groups. Then, sampling was performed immediately and after 24 hours after exercise. Exhausting endurance exercise program involved increasing the speed of treadmill until getting exhausted. Fibrinogen, APTT, and PT were measured with the Clause and coagulation methods. The analysis was performed by using independent t-test, one-way variance analysis and tukey test. Significance level was assigned for all statistical analysis (p≤0.050. Results: Results in immature and mature rats groups indicated that amounts of fibrinogen has had significant reduction immediately after exercise (p=0.004, p=0.047, and 24 hours after exercise were significantly increased only in mature rats (p=0.000. Also, APTT in all groups decreased immediately and 24 hours after exercise but it was significant just 24 hours after exercise. Conclusion: Due to the increased fibrinogen and decreased APTT at 24 hours after exhaustive endurance exercise in mature and immature rats, it seems that performing such activities in children and inactive adults must be accompanied with special considerations.

On the Consequences of the U.S. Withdrawal from the Kyoto/Bonn Protocol

International Nuclear Information System (INIS)

Buchner, B.; Cersosimo, I.; Carraro, C.

2001-12-01

The US decision not to ratify the Kyoto Protocol and the recent outcomes of the Bonn and Marrakech Conferences of the Parties have important implications for both the effectiveness and the efficiency of future climate policies. Among these implications, those related with technical change and with the functioning of the international market for carbon emissions are particularly relevant, because these variables have the largest impact on the overall abatement cost to be borne by Annex B countries in the short and in the long run. This paper analyses the consequences of the US decision to withdraw from the Kyoto/Bonn Protocol both on technological innovation and on the price of emission permits (and, as a consequence, on abatement costs). A first goal is to assess the impact of the US defection on the price of permits and compliance costs when technological innovation and diffusion is taken into account (the model embodies international technological spillovers). A second goal is to understand for what reasons in the presence of endogenous and induced technical change the reduction of the price of permits is lower than in most empirical analyses recently circulated. A third goal is to assess the role of Russia in climate negotiations, its increased bargaining power and its eventual incentives to follow the US defections

Analyzing the Kyoto Protocol under the Marrakesh Accords. Economic efficiency and environmental effectiveness

International Nuclear Information System (INIS)

Den Elzen, Michel G.J.; De Moor, Andre P.G.

2002-01-01

This article evaluates the environmental effectiveness and economic implications of the Kyoto Protocol (KP) after the Bonn agreement and the Marrakesh Accords. We will break it down into several components that correspond with major steps in the international process: pre-COP 6 version of the KP, with unrestricted international emissions trading but without sinks; withdrawal of the USA; and decisions on sinks in Bonn and Marrakesh. The Marrakesh Accords bring Annex-I emissions in 2010 without the USA at 0.5% under base-year levels; this corresponds to nearly 2% above the 1990-levels. The US withdrawal has by far the greatest impact in reducing the environmental effectiveness of the KP, whereas the impact of the decision on sinks is comparatively small. The US withdrawal also substantially reduces the permit demand and permit prices will drop dramatically. Hot air becomes increasingly dominant and may threaten the viability of the Kyoto Mechanisms (KM), especially in lower baseline (business-as-usual (BaU)) scenarios. Therefore, banking of hot air is of absolute importance to improve the environmental effectiveness of the protocol at moderately higher costs, while enhancing the development of a viable emission trading market. A strategy of curtailing and banking permit supply is also in the interest of the dominant seller, Russia

Summary report of activities under visiting research program in Research Reactor Institute, Kyoto University, second half of 1989

International Nuclear Information System (INIS)

1990-07-01

The Technical Report is published on occasion by summarizing in the form of prompt report the data required at the time of research and experiment, such as the results of the functional test on various experimental facilities, the test results for the articles made for trial, the state of radiation control and waste treatment, the reports of study meetings and so on, or the remarkable results and new methods obtained in research, the discussion on other papers and reports and others in the Research Reactor Institute, Kyoto University. In this report, the gists of 69 studies carried out by using the Research Reactor and 15 studies by using the Kyoto University Critical Assembly are collected. Adoption number, classification, title, the names of reporters and gist are given for each report. (K.I.)

Alterations in substance P binding in brain nuclei of spontaneously hypertensive rats

International Nuclear Information System (INIS)

Shigematsu, K.; Niwa, M.; Kurihara, M.; Castren, E.; Saavedra, J.M.

1987-01-01

Substance P binding sites were characterized in brain nuclei of young (4-wk-old) and adult (16-wk-old) spontaneously hypertensive rats (SHR) and age-matched normotensive Wistar-Kyoto (WKY) control rats by quantitative autoradiography. Young SHR presented higher affinity constants (K/sub A/) than young WKY. The changes were restricted to locus coeruleus, the area postrema, the dorsal motor nucleus of the vagus, and to discrete areas located in lobes 9 and 10 of the vermis cerebelli of SHR. There were no differences in the maximal binding capacity (B/sub max/) except in the nucleus ambiguus where the B/sub max/ was lower than WKY. Conversely, the number of substance P binding sites was higher in the locus coeruleus, the nucleus tegmentalis dorsalis, the nucleus ambiguus, the dorsal motor nucleus of the vagus, the hypoglossal nucleus, the inferior olivary nucleus, and lobes 9 and 10 of the vermis cerebelli of adult SHR when compared with adult WKY. The results support the hypothesis of a role for brain substance P in blood pressure regulation and in genetic hypertension in rats

Karl Popper: antes y después de Kyoto

Directory of Open Access Journals (Sweden)

Zanotti, Gabriel

1999-06-01

Full Text Available Not available.En su último libro sobre Karl Popper, Mariano Artigas plantea una hermenéutica revolucionaria: muestra que la ética de Popper es el fundamento de su epistemología, y que el fundamento de esa ética está lejos del «conjeturalismo» que suele atribuirse a Popper. Artigas analiza qué significa en Popper la «fe irracional en la razón» y utiliza, como fuente inédita, el dramático relato que hace Popper de su relación con W. W. Bartley, por primera vez, en Kyoto, en 1992. Sea cual fuere la opinión del lector, el libro de Artigas divide la hermenéutica de Popper en un antes y un después.

Endogenous induced technical change and the costs of Kyoto

International Nuclear Information System (INIS)

Buonanno, Paolo; Carraro, Carlo; Galeotti, Marzio

2003-01-01

We present a model for climate change policy analysis which accounts for the possibility that technology evolves endogenously and that technical change can be induced by environmental policy measures. Both the output production technology and the emission-output ratio depend upon a stock of knowledge, which accumulates through R and D activities. Two versions of this model are studied, one with endogenous technical change but exogenous environmental technical change and the other with both endogenous and induced technical change. A third version also captures technological spillover effects. As an application, the model is simulated allowing for trade of pollution permits as specified in the Kyoto Protocol and assessing the implications in terms of cost efficiency, economic growth and R and D efforts of the three different specifications of technical change

Construction of 100 MeV electron linac in Kyoto University

International Nuclear Information System (INIS)

Shirai, Toshiyuki; Sugimura, Takeshi; Kando, Masaki

1995-01-01

An electron linear accelerator and a compact storage ring have been constructed at Kyoto University. The beam energy of the storage ring is 300 MeV and will be utilized as a synchrotron radiation source. The output beam energy of the linac is 100 MeV and the designed beam current is 100 mA at the pulse width of 1 μsec. The construction of the linac had been finished and the test is under going. The electron beam of 300 mA is extracted from the electron gun and the peak RF power of 20 MW is successfully fed to the accelerating structures at the pulse width of 2 μsec. (author)

From Kyoto to Bonn: implications and opportunities for renewable energy

International Nuclear Information System (INIS)

Pugliese, M.; Cameron, J.; Wilder, M.

2001-01-01

The article discusses the need for the uptake of renewable energy sources to increase to meet the commitments made in Bonn in July for compliance with the Kyoto Protocol. The article is presented under the sub-headings of: (i) the Bonn Agreement; (ii) implications and opportunities for renewable energy; (iii) the commercialisation and mainstreaming of renewable energy technologies; (iv) greenhouse gas-reducing projects (v) renewable portfolio standards and renewable certificate trading programmes; (vi) increased funding for product and technology development; (vii) emissions trading; (viii) domestic legislation and initiatives; (ix) regulatory effects in Annex I countries specifically impacting renewable energy (UK, Germany, Australia, EU Renewable Energy Law) and (x) US efforts in the absence of a national climate policy

Latest approaches of Kyoto protocol

International Nuclear Information System (INIS)

Matei, M.; Matei, L.

2005-01-01

Recently EURELECTRIC welcome the proposal of new EC Directive concerning the inclusion in the EU Emissions Trading Scheme (ETS) of credits from the project mechanisms - Joint Implementation (JI) and Clean Development Mechanism (CDM). The proposed Directive is an amendment to the EU Emissions Trading Directive adopted in June 2003. EURELECTRIC calls for unlimited use of credits in ETS. The draft Directive provides for the application of these mechanisms to begin as of 2008, on condition that the Kyoto Protocol does actually enter into force, an event which is still dependent on Russia's ratification. Such ratification has been subject to contradictory statements from the Russian Government, and the question of whether their signature to the Protocol is forthcoming is still fraught with uncertainty. Although it is not anticipated that significant quantities of JI or CDM certified credits will be available in the period 2005-2007, those that do become available would provide some additional liquidity in the emissions trading market. There is a direct relation between the coming ETS and electricity pricing: environmental policy is the driver, based on the need to switch to a low-carbon future and manage the necessary investments in a rational manner - and emissions trading is the best solution available. Romania has good opportunities to be involved in the greenhouse gases market, both in ETS and JI mechanisms. Some JI projects between Romanian and The Netherlands are already done or underway. (author)

Emission Trading under the Kyoto Protocol

Energy Technology Data Exchange (ETDEWEB)

Holtsmark, Bjart; Hagem, Cathrine

1998-12-01

This report discusses the potential gains from emission trading and raises some crucial questions. It shows that the total costs of the Kyoto Protocol could be reduced by about 95% through emission trading. Emission trading is an option also in the domestic arenas. The governments of the Annex B countries may allocate emission quotas to local enterprises as emission permits. Thus new markets for greenhouse gas emission quotas may emerge, domestically and internationally. It is emphasized that emission trading at the national and international levels must be discussed separately. The Nordic governments, for example, will find several good reasons for supporting emission trading at the international level if not necessarily domestically. The Nordic countries have already implemented domestic taxes on CO{sub 2} emissions and this tax policy could be sustained while these governments support and take part in emission trading at the international level.The report also considers a possible side effect of emission trading: free emission trading among Annex B countries could reduce the total abatement compared to a non-tradable policy as a consequence of the fact that some of the countries that are in transition to a market economy may be given emission limitations above their business-as-usual emissions. 40 refs., 7 figs., 4 tabs.

Pengaruh Jamu Dengan Tribulus Terrestris Terhadap Kualitas Sperma Tikus Wistar Jantan (Rattus Norvegicus)

OpenAIRE

Pelealu, Delano; Tendean, Lydia; Wantouw, Benny

2015-01-01

: Tribulus terrestris dikenal sebagai bahan yang dapat memperbaiki kualitas sperma. Salah satu jenis jamu yang diproduksi di Indonesia mengandung Tribulus terrestris Penelitian ini bertujuan untuk mengetahui pengaruh jamu dengan Tribulus terrestris terhadap konsentrasi, motilitas, dan morfologi spermatozoa tikus wistar jantan (Rattus norvegicus). Penelitian ini menggunakan metode eksperimental. Sampel 9 ekor tikus wistar jantan (Rattus norvegicus) dibagi menjadi 3 kelompok yakni, kelompok P0 ...

Solanum muricatum Aiton Juice as A Hepatoprotective Agent in Wistar Rats Induced With Carbon Tetrachloride

Directory of Open Access Journals (Sweden)

Justine Sim Wei Yang

2015-12-01

Full Text Available Background: Liver participates in various metabolic processes in human body. Exposures to toxins such as carbon tetrachloride (CCl4 results in hepatocyte destruction and release the cell contents. Enzymes such as serum glutamic pyruvic transaminase (SGPT were used as a parameter to diagnose liver damage. Pepino (Solanum muricatum Aiton contains antioxidants that protect liver from hepatoxicity. The aim of this experiment is to determine the effect of pepino in protecting the hepatocyte from hepatotoxic effect of CCl4. Methods: A total of 16 Wistar rats used as the subject were divided into Control and Therapeutic Group. The Control group was induced with CCl4 but was not given pepino juice. Meanwhile, the Therapeutic Group was given pepino juice for 10 days. For induction of hepatotoxicity, CCl4 10% was given at a dosage of 2.0 ml/kg intra-peritoneal. Each Wistar rat in Therapeutic Group was given 1.0 ml of 300 g/ml pepino juice via oral feeding. Spectrophotometer with adjusted wavelength of 340 nm was used to measure SGPT level of the Wistar rats and statistical T-test was used to analyze the data. Results: Wistar rats in Therapeutic group showed a larger decrease (6898.9 IU/L–79.1 IU/L in SGPT level compared to the Control group (6469.8 IU/L–418.5 IU/L. The SGPT level of the Wistar rat in Therapeutic group reached normal baseline (50 IU/L–150 IU/L. The significance of the experiment was supported by the T-test, P-value <0.05 Discussion: Pepino juice had antioxidants that protect the hepatocyte of Wistar rats from free radicals. The synergistic action of antioxidants and hepatocyte regeneration of Wistar rats in Therapeutic group caused a decrease in SGPT level. Therefore, the experiment concluded that pepino juice at the dosage of 300 g/ml has hepatoprotective effect.

Benchmarks of subcriticality in accelerator-driven system at Kyoto University Critical Assembly

Directory of Open Access Journals (Sweden)

Cheol Ho Pyeon

2017-09-01

Full Text Available Basic research on the accelerator-driven system is conducted by combining 235U-fueled and 232Th-loaded cores in the Kyoto University Critical Assembly with the pulsed neutron generator (14 MeV neutrons and the proton beam accelerator (100 MeV protons with a heavy metal target. The results of experimental subcriticality are presented with a wide range of subcriticality level between near critical and 10,000 pcm, as obtained by the pulsed neutron source method, the Feynman-α method, and the neutron source multiplication method.

Clean Development Mechanism” projects in the developing countries within the Kyoto protocol: problem analysis of a case study in Morocco

Directory of Open Access Journals (Sweden)

Gaglioppa P

2009-11-01

Full Text Available An internship period spent in the north of Morocco kingdom (Tetouan gave a contribute to the organization activity in promoting sustainable development in the rural areas under the Kyoto Protocol. The multitasking project will increase biodiversity planting trees for wood, forage and fruits productions. The paper show a first step study to evaluate the possibility to reach an agreement with the propriety and the manager of these areas in a multifunctional reforestation project. The eligible site suitable for reforestation in accordance with the CDM international scheme is a large plateau (more than 5000 hectares 600 meters high on the sea level far from the Cannabis crops area. The evaluation of the project costs and of the social benefits for the population consider (using different species the indigenous communities necessity. The evaluation of carbon sequestration show the small scale of the reforestation project on behalf of the Kyoto Protocol, but give also an idea about the people rights and necessities. The normal afforestation and reforestation projects, under the Kyoto Protocol, try to maximize the CO2 sequestration in a short time, than business laws usually require. A small scale project could be self-managing, less expensive (international certification costs and more interesting for local communities.

Serum Trace Element Presentation in Female Wistar Rats ...

African Journals Online (AJOL)

Serum Trace Element Presentation in Female Wistar Rats administered with Paracetamol & Paracetamol/Methionine. AA Iyanda, FAA Adeniyi. Abstract. A number of therapeutic agents are known to alter serum trace element levels with dangerous consequences. An earlier study had demonstrated significant alteration in the ...

EFFECTS OF EARLY POSTNATAL ANOXIA ON ADULT LEARNING AND EMOTION IN RATS

NARCIS (Netherlands)

BUWALDA, B; NYAKAS, C; VOSSELMAN, HJ; LUITEN, PGM; Vosselman, Henk Jan

Cognitive functioning, behavioural attention and anxiety were studied in adult male Wistar rats after early postnatal anoxia. Spatial memory performance in the holeboard learning task was impaired in anoxic rats when compared with control animals. Attention assessed by the behavioural immobility

Impacts of the Kyoto protocol on U.S. energy markets and economic activity

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-10-01

The Intergovernmental Panel on Climate Change (IPCC) was established by the World Meteorological Organization and the United Nations Environment Program in 1988 to assess the available scientific, technical, and socioeconomic information in the field of climate change. The most recent report of the IPCC concluded that ``Our ability to quantify the human influence on global climate is currently limited because the expected signal is still emerging from the noise of natural variability, and because there are uncertainties in key factors. These include the magnitudes and patterns of long-term variability and the time-evolving pattern of forcing by, and response to, changes in concentrations of greenhouse gases and aerosols, and land surface changes. Nevertheless the balance of evidence suggests that there is a discernible human influence on global climate. The first and second Conference of the Parties in 1995 and 1996 agreed to address the issue of greenhouse gas emissions for the period beyond 2000, and to negotiate quantified emission limitations and reductions for the third Conference of the Parties. On December 1 through 11, 1997, representatives from more than 160 countries met in Kyoto, Japan, to negotiate binding limits on greenhouse gas emissions for developed nations. The resulting Kyoto Protocol established emissions targets for each of the participating developed countries--the Annex 1 countries--relative to their 1990 emissions levels. 114 refs., 138 figs., 33 tabs.

Impacts of the Kyoto protocol on U.S. energy markets and economic activity

International Nuclear Information System (INIS)

1998-10-01

The Intergovernmental Panel on Climate Change (IPCC) was established by the World Meteorological Organization and the United Nations Environment Program in 1988 to assess the available scientific, technical, and socioeconomic information in the field of climate change. The most recent report of the IPCC concluded that ''Our ability to quantify the human influence on global climate is currently limited because the expected signal is still emerging from the noise of natural variability, and because there are uncertainties in key factors. These include the magnitudes and patterns of long-term variability and the time-evolving pattern of forcing by, and response to, changes in concentrations of greenhouse gases and aerosols, and land surface changes. Nevertheless the balance of evidence suggests that there is a discernible human influence on global climate. The first and second Conference of the Parties in 1995 and 1996 agreed to address the issue of greenhouse gas emissions for the period beyond 2000, and to negotiate quantified emission limitations and reductions for the third Conference of the Parties. On December 1 through 11, 1997, representatives from more than 160 countries met in Kyoto, Japan, to negotiate binding limits on greenhouse gas emissions for developed nations. The resulting Kyoto Protocol established emissions targets for each of the participating developed countries--the Annex 1 countries--relative to their 1990 emissions levels. 114 refs., 138 figs., 33 tabs

Impact of the recession on the realization of the Kyoto target and the 2011 target of the working programme 'Clean and Efficient'. Memo

International Nuclear Information System (INIS)

2009-01-01

By request of the Dutch Ministry of Housing, Spatial Planning and the Environment the Environmental Assessment Agency (PBL) drew up this memo on the impact of the recession on the realization of the Kyoto target and the intermediate target for 2011 from the working programme Clean and Efficient. The main conclusion of this memo is that both with and without the recession the Kyoto target will probably be realized. The main difference lies in the volume of emission allowances deployed by the government to realize the target [mk] [nl

Comprehensive geriatric intervention program with and without weekly class-style exercise: research protocol of a cluster randomized controlled trial in Kyoto-Kameoka Study

Directory of Open Access Journals (Sweden)

Watanabe Y

2018-05-01

Full Text Available Yuya Watanabe,1–4,* Yosuke Yamada,2,4,* Keiichi Yokoyama,2,5,6,* Tsukasa Yoshida,2,4,7 Yasuko Yoshinaka,5,6 Mie Yoshimoto,8 Yoko Tanaka,9 Aya Itoi,10 Emi Yamagata,11 Naoyuki Ebine,1 Kazuko Ishikawa-Takata,12 Misaka Kimura2,3 1Faculty of Health and Sports Science, Doshisha University, Kyotanabe, Japan; 2Laboratory of Applied Health Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan; 3Department of Health and Sports Sciences, Kyoto Gakuen University, Kameoka, Japan; 4Section of Healthy Longevity Research, National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan; 5Specified Non-profit Corporation Genki-up AGE Project, Kameoka, Japan; 6Department of Business Administration, Kyoto Gakuen University, Kyoto, Japan; 7Senior Citizen’s Welfare Section, Kameoka City Government, Kameoka, Japan; 8Corporation of Japan Dental Hygienists’ Association, Kyoto, Japan; 9Kyoto Dietetic Association, Kyoto, Japan; 10Department of Health, Sports and Nutrition, Faculty of Health and Welfare, Kobe Women’s University, Kobe, Japan; 11Faculty of Nursing, Doshisha Women’s College of Liberal Arts, Kyotanabe, Japan; 12Department of Nutrition and Metabolism, National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan *These authors contributed equally to this work Objective: The number of long-term care (LTC users and the associated expenditures in Japan are increasing dramatically. The national government recommends LTC prevention through activation of communities. However, there is no clear evidence of the effect of population-based comprehensive geriatric intervention program (CGIP for restraints of LTC users and the associated expenditures in the future. The aims of the current paper are to describe the study protocol and progress of a cluster randomized controlled trial (RCT with a CGIP in Kameoka City. Methods: The

The Kyoto Protocol: one more stage in the climate change negotiations

International Nuclear Information System (INIS)

Maruri Londono, Enrique

1998-02-01

This article notices on the internal difficulties that will be generated around the ratification of the Kyoto Protocol in developed countries as United States, Canada and Japan, given the position of industries like the vehicles and the energetic, that try to dilate the commitments assumed in December of 1997. It is emphasized in the North American case, taking into account their contribution in the global greenhouse gases emissions and the importance of their participation in an international agreement on the topic of the climate change, assuming a critical position about the Senate's decision of conditioning the agreement's ratification to the assumption of commitments of developing countries

Efficacy of the Kyoto Classification of Gastritis in Identifying Patients at High Risk for Gastric Cancer.

Science.gov (United States)

Sugimoto, Mitsushige; Ban, Hiromitsu; Ichikawa, Hitomi; Sahara, Shu; Otsuka, Taketo; Inatomi, Osamu; Bamba, Shigeki; Furuta, Takahisa; Andoh, Akira

2017-01-01

Objective The Kyoto gastritis classification categorizes the endoscopic characteristics of Helicobacter pylori (H. pylori) infection-associated gastritis and identifies patterns associated with a high risk of gastric cancer. We investigated its efficacy, comparing scores in patients with H. pylori-associated gastritis and with gastric cancer. Methods A total of 1,200 patients with H. pylori-positive gastritis alone (n=932), early-stage H. pylori-positive gastric cancer (n=189), and successfully treated H. pylori-negative cancer (n=79) were endoscopically graded according to the Kyoto gastritis classification for atrophy, intestinal metaplasia, fold hypertrophy, nodularity, and diffuse redness. Results The prevalence of O-II/O-III-type atrophy according to the Kimura-Takemoto classification in early-stage H. pylori-positive gastric cancer and successfully treated H. pylori-negative cancer groups was 45.1%, which was significantly higher than in subjects with gastritis alone (12.7%, pgastritis scores of atrophy and intestinal metaplasia in the H. pylori-positive cancer group were significantly higher than in subjects with gastritis alone (all pgastritis classification may thus be useful for detecting these patients.

Capping the Cost of Compliance with the Kyoto Protocol and Recycling Revenues into Land-Use Projects

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Bernhard Schlamadinger

2001-01-01

Full Text Available There is the concern among some countries that compliance costs with commitments under the Kyoto Protocol may be unacceptably high. There is also the concern that technical difficulties with the inclusion of land use, land-use change, and forestry activities in non-Annex I countries might lead to an effective exclusion of such activities from consideration under the Protocol. This paper is proposing a mechanism that addresses both these concerns. In essence, it is suggested that parties should be able to purchase fixed-price offset certificates if they feel they cannot achieve compliance through other means alone, such as by improved energy efficiency, increased use of renewable energy, or use of the flexible mechanisms in the Kyoto Protocol. These offset certificates would act as a price cap for the cost of compliance for any party to the Protocol. Revenues from purchase of the offset certificates would be directed to forest-based activities in non-Annex I countries such as forest protection that may carry multiple benefits including enhancing net carbon sequestration.

Capping the cost of compliance with the Kyoto Protocol and recycling revenues into land-use projects.

Science.gov (United States)

Schlamadinger, B; Obersteiner, M; Michaelowa, A; Grubb, M; Azar, C; Yamagata, Y; Goldberg, D; Read, P; Kirschbaum, M U; Fearnside, P M; Sugiyama, T; Rametsteiner, E; Böswald, K

2001-07-14

There is the concern among some countries that compliance costs with commitments under the Kyoto Protocol may be unacceptably high. There is also the concern that technical difficulties with the inclusion of land use, land-use change, and forestry activities in non-Annex I countries might lead to an effective exclusion of such activities from consideration under the Protocol. This paper is proposing a mechanism that addresses both these concerns. In essence, it is suggested that parties should be able to purchase fixed-price offset certificates if they feel they cannot achieve compliance through other means alone, such as by improved energy efficiency, increased use of renewable energy, or use of the flexible mechanisms in the Kyoto Protocol. These offset certificates would act as a price cap for the cost of compliance for any party to the Protocol. Revenues from purchase of the offset certificates would be directed to forest-based activities in non-Annex I countries such as forest protection that may carry multiple benefits including enhancing net carbon sequestration.

PROTOCOLO DE KYOTO: DEBATE SOBRE AMBIENTE Y DESARROLLO EN LAS DISCUSIONES SOBRE CAMBIO CLIMÁTICO

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Rodríguez S. Liliana

2008-07-01

Full Text Available El comportamiento climático del planeta y sus consecuencias han propiciado debates sobre los modelos de desarrollo de los países responsables del deterioro acelerado del ambiente y de los fenómenos naturales por estos días recurrentes. Sin embargo, países como Estados Unidos, luego de firmar compromisos como la Convención sobre Cambio Climático, rehúsan adquirir las obligaciones del Protocolo de Kyoto, por temor a sufrir deterioro en sus economías. En este escenario, donde la nación responsable de la emisión de aproximadamente 36% de los gases efecto invernadero resultado de la acción humana en el planeta no se compromete a adoptar políticas restrictivas tendientes a hacer sus modelos de producción más amigables con la naturaleza a pesar de que dichas medidas empiezan a ser impuestas a otras naciones como condicionantes en las negociaciones comerciales internacionales, parece ser que la adopción del Protocolo de Kyoto para países en desarrollo como Colombia no es del todo benéfica.

Detecting DNA synthesis of neointimal formation after catheter balloon injury in GK and in Wistar rats: using 5-ethynyl-2'-deoxyuridine

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Guo Jingsheng

2012-12-01

Full Text Available Abstract Background Neointimal formation plays an important role in the pathogenesis of coronary restenosis after percutaneous coronary intervention (PCI, especially in patients with diabetes mellitus. Recently, some studies have shown that 5-ethynyl-2'-deoxyuridine (EdU incorporation can serve as a novel alternative to the 5-bromo-2'-deoxyuridine (BrdU antibody detection method for detection of DNA synthesis in regenerating avian cochlea, chick embryo and the adult nervous system. However, few studies have been performed to assess the suitability of EdU for detecting DNA synthesis in vascular neointima. Methods The carotid artery balloon injury model was established in Goto-Kakizaki (GK and Wistar rats. A Cell-LightTM EdU Kit was used to detect EdU-labeled cell nuclei of common carotid arteries at day 7 after catheter balloon injury. Different methods of injecting EdU were tested. The protein levels of proliferating cell nuclear antigen (PCNA and p-Akt (Ser473, as well as the mRNA levels of PCNA were evaluated by Western blotting and quantitative real-time PCR (qRT-PCR, respectively. Immunohistochemical staining was also employed to visualize PCNA-positive cells. Results At day 7 after catheter balloon injury, far more EdU-positive and PCNA-positive cells were observed in GK rats. When comparing groups that received different EdU doses, it was found that the percentage of EdU-positive cells at a dose of 100 mg/kg body weight was than at doses of 25 mg/kg and 50 mg/kg. The number of positive cells was significantly higher in the repeated injection group compared to the single injection group. Further, after balloon injury DNA synthesis in GK rats was more notable than in Wistar rats. Neointimal formation in GK rats was more obvious than in Wistar rats. The protein levels of PCNA and p-Akt (Ser473 and the mRNA levels of PCNA were increased in injured rats as compared to uninjured rats, and were significantly higher in GK rats than in Wistar rats

MORPHOMETRIC EFFECTS OF COLA NITIDA EXTRACT ON THE STOMACH OF ADULT MALE WISTAR RATS

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Ojo Gideon B

2010-01-01

Full Text Available Cola nut was investigated for possible harmful effect on the morphology of the stomach, considering its wide consumption and documented antioxidant properties.Twenty-five Adult male Wistar rats with average weight of 167.6 g and randomly divided into five groups A, B, C, D and E each containing five animals. Care of the animal according to the Rules and Guidelines of the Animal Right Committee of the Obafemi Awolowo University, Ile-Ife, Nigeria was adopted. The rats in group A (control were given distilled water while animals in experimental groups B, C, D and E were each given 600 mg/kg body weight of crude extract of Cola nitida by oral intubation for consecutive three, five, seven and nine days respectively and sacrificed. The stomach was excised, quickly fixed in 10% formal saline and processed histologically, using routine haematoxylin and eosin (H and E stain. The stained sections were subjected to morphometrics analysis at a magnification of sign 40 using the eye piece micrometer procedure.The result revealed a significant reduction in the epithelia thickness of the experimental animals, (Groups A=218.40 µm ± 144.61 vs. B=117.00 µm ± 34.88, C=124.80 µm ± 87.01, D=96.60 µm ± 60.04 and E=108.57 µm ± 122.16 (t=3.04, 2.48, 3.57 and 2.58 respectively, p 0.05 and (A=148.20 µm ± 50.56 vs. B=109.20 µm ± 22.27, C=117.00 µm ± 11.07, D=124.80 µm ± 71.67, E=162.86 µm ± 112.35 (t=1.58, 1.35, 0.60, and 0.46 respectively, p<0.05.The thickness of the muscularis mucosa and muscularis externa were significantly increased by the extract, (Groups A=140.40 µm ± 95.84 vs. B=358.80 µm ± 323.07, C=260.00 µm ± 32.89, D=306.80 µm ± 148.90, E=374.83 µm ± 175.44 (t=7.16, 6.36, 3.83, and 2.89 respectively, p<0.05 and (140.4 µm ± 47.94 vs. B=358.80 µm ±161.53, C=260.00 µm ± 16.44, D=306.80 µm ± 74.44, E=374.83 µm ± 87.72 (t=2.90, 5.22, 4.20, and 5.22 respectively, p<0.05.It is therefore evident that the consumption of cola nut

Grooming behavior of spontaneously hypertensive rats

NARCIS (Netherlands)

Buuse, M. van den; Jong, Wybren de

1987-01-01

In an open field spontaneously hypertensive rats (SHR) exhibited lower scores for grooming when compared to their normotensive controls, the Wistar Kyoto rats (WKY). After i.c.v. injection of 1 μg ACTH1–24 cumulative 50-min grooming scores were lower in SHR. Analysis of subscores indicated that the

Changes caused by haloperidol are blocked by music in Wistar rat.

Science.gov (United States)

Tasset, Inmaculada; Quero, Ismael; García-Mayórgaz, Ángel D; del Río, Manuel Causse; Túnez, Isaac; Montilla, Pedro

2012-06-01

This study sought to evaluate the effect of classical music, using Mozart's sonata for two pianos (K. 448), on changes in dopamine (DA) levels in the striatal nucleus (SN), prefrontal cortex (PFC) and mesencephalon, and on prolactin (PRL) and corticosterone secretion in adult male Wistar rats. Rats were divided into four groups: (1) control, (2) haloperidol treatment (single dose of 2 mg/kg s.c.), (3) music (two 2-h sessions per day) and (4) haloperidol plus music. Rats were sacrificed 2 h after haloperidol injection. Music prompted a fall in plasma PRL and corticosterone levels in healthy rats (P music was associated with a significant increase in DA levels in all groups, with the increase being particularly marked in PFC and SN (P music, by contrast, enhances DA activity and turnover in the brain. The results obtained here bear out reports that music triggers a reduction in systolic pressure and an increase in mesencephalon dopamine levels in human and rats treated with ecstasy, through a calmodulin-dependent system.

Development of a national forest inventory for carbon accounting purposes in New Zealand's planted Kyoto forests

Science.gov (United States)

John Moore; Ian Payton; Larry Burrows; Chris Goulding; Peter Beets; Paul Lane; Peter Stephens

2007-01-01

This article discusses the development of a monitoring system to estimate carbon sequestration in New Zealand's planted Kyoto forests, those forests that have been planted since January 1, 1990, on land that previously did not contain forest. The system must meet the Intergovernmental Panel on Climate Change good practice guidance and must be seen to be unbiased,...

JPRS Report, Science & Technology, Japan, International Society of Electrochemistry Meeting (40th) Held in Kyoto on 17-22 Sep 89

National Research Council Canada - National Science Library

1990-01-01

Selected "extended abstracts" presented at the 40th International Society of Electrochemistry Meeting held 17-22 Sep 89 in Kyoto, sponsored by the International Union of Pure and Applied Chemistry (IUPAC...

Opposite lipemic response of Wistar rats and C57BL/6 mice to dietary glucose or fructose supplementation

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C.R. Barbosa

2007-03-01

Full Text Available The metabolic effects of carbohydrate supplementation in mice have not been extensively studied. In rats, glucose- and fructose-rich diets induce hypertriacylglycerolemia. In the present study, we compared the metabolic responses to two monosaccharide supplementations in two murine models. Adult male Wistar rats (N = 80 and C57BL/6 mice (N = 60, after 3 weeks on a standardized diet, were submitted to dietary supplementation by gavage with glucose (G or fructose (F solutions (500 g/L, 8 g/kg body weight for 21 days. Glycemia was significantly higher in rats after fructose treatment (F: 7.9 vs 9.3 mM and in mice (G: 6.5 vs 10 and F: 6.6 vs 8.9 mM after both carbohydrate treatments. Triacylglycerolemia increased significantly 1.5 times in rats after G or F supplementation. Total cholesterol did not change with G treatment in rats, but did decrease after F supplementation (1.5 vs 1.4 mM, P < 0.05. Both supplementations in rats induced insulin resistance, as suggested by the higher Homeostasis Model Assessment Index. In contrast, mice showed significant decreases in triacylglycerol (G: 1.8 vs 1.4 and F: 1.9 vs 1.4 mM, P < 0.01 and total cholesterol levels (G and F: 2.7 vs 2.5 mM, P < 0.05 after both monosaccharide supplementations. Wistar rats and C57BL/6 mice, although belonging to the same family (Muridae, presented opposite responses to glucose and fructose supplementation regarding serum triacylglycerol, free fatty acids, and insulin levels after monosaccharide treatment. Thus, while Wistar rats developed features of plurimetabolic syndrome, C57BL/6 mice presented changes in serum biochemical profile considered to be healthier for the cardiovascular system.

Comparative Studies on the Cardiovascular System in the Wistar ...

African Journals Online (AJOL)

PROF HORSFALL

http://ww.bioline.org.br/ja. Comparative Studies on the Cardiovascular System in the Wistar Rat (Rattus .... norvegicus) were gotten from the animal house of the. Department of Anatomy .... Locomotion and Respiration in. Marine Air – Breathing ...

August rats are more resistant to arrhythmogenic effect of myocardial ischemia and reperfusion than Wistar rats.

Science.gov (United States)

Belkina, L M; Kirillina, T N; Pshennikova, M G; Arkhipenko, Yu V

2002-06-01

As differentiated from Wistar rats, myocardial ischemia and reperfusion produce no ventricular fibrillation in August rats. Pretreatment with nitric oxide synthase inhibitor Nw-nitro-L-arginine increased mortality rate in August rats with acute myocardial infarction from 20 to 40%. Under these conditions mortality rate in Wistar rats increased from 50 to 71%. Interstrain differences in the resistance of these animals to the arrhythmogenic effect of ischemia are probably associated with higher activity of the nitric oxide system in August rats compared to Wistar rats.

Effect of Consuming Iodized Salt on Fertility Indices in Male Adult Rats

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M. Mehrabani Natanzi

2017-06-01

Full Text Available Introduction: Today about 27.4 percent of female 15-44 years and 1 percent of female in fertility age are affected by infertility. Iodine is a rare element that is essential for the synthesis of thyroid hormones. Concentration of the thyroid hormones in blood under the influence of iodine intake and changes in thyroid hormones levels interact with reproductive system. Today, all the people of Iran consuming iodized salt regardless of iodine status in their body. In this study according to high prevalence of the infertility among young couples, iodized salt intake on fertility in male rats were investigated. Materials and Methods: In this study 20 male and 20 female adult Wistar rats were used. Twenty male adult Wistar rats were randomly divided into 2 groups. Including the control group and treatment group that received iodine and female adult Wistar were fed with a regular diet. Five male rats from each group were killed at the end of the fourth weeks in order to evaluate the possible effect of iodized salt on sperm analysis and weight of testis. After a month, male and female rats were placed in pairs in separate cages and their offspring were investigated in terms of number, gender and health. Results: The result of this study showed that the number of healthy offspring of treated male rats was significantly lower than the control group. Conclusion: Due to the negative effect of excessive iodine intake on fertility rate, it is recommended to couples to perform functional tests of their thyroid glands before intake of iodized salts.

Educational use of research reactor (KUR) and critical assembly (KUCA) at Kyoto University

International Nuclear Information System (INIS)

Misawa, Tsuyoshi; Unesaki, Hironobu; Ichihara, Chihiro; Pyeon, Cheol Ho; Shiroya, Seiji

2005-01-01

At Kyoto University Research Reactor Institute, a research reactor of 5MW (KUR) and a critical assembly (KUCA) have been used for educational purpose to train undergraduate or graduate students. Using KUR, basic experiments for neutron applications have been carried out, and KUCA has been used for the education of nuclear engineering and technology. Especially, using KUCA, a joint reactor laboratory course of graduate level is offered every summer since 1975 by nine associated Japanese universities, and more than 2200 students attended this course

Comparative evaluation of the sperm characteristics and morphology of adult Wistar rats fed either low or normal protein-energy diets and orally dosed with aqueous Cuscuta australis extracts.

Science.gov (United States)

Omirinde, J O; Ozegbe, P C; Oyeyemi, M O

2014-06-19

Cuscuta australis (C. australis) seed and stem are commonly used as dietary supplements in a maize-meal, "Ogi", by the local population for the management of male and female reproductive dysfunctions. This study, as a part of on-going efforts, therefore, evaluated and compared the effects of Low Protein-energy (LP) and Normal Protein-energy (NP) diets on the sperm morphology and characteristics of adult Wistar rats orally dosed aqueous extracts of C. australis seed (LPSE and NPSE) and stem (LPST and NPST), 300 mg of extract/kg body weight of rat/day, for seven days. The control groups (LPWA and NPWA) received vehicle, water. Live-dead ratio and percentage of sperms with curved tail were significantly decreased (p<0.01) in the NPST relative to the NPWA, LPWA, LPST, NPSE and LPSE. Total abnormal sperm counts, acephalic sperms and tailless head sperms were significantly decreased (p<0.001, p<0.05 and p<0.001, respectively) in the LPST and NPST relative to LPSE, NPSE, LPWA and NPWA. The LPSE, LPST and NPST showed significantly decreased (p<0.05) percentages of sperms with either bent mid-piece or curved mid-piece relative to the LPWA. Significantly decreased (p<0.05) percentage of sperms with curved mid-piece was also observed in the NPSE relative to LPWA. Protein-energy diet significantly influenced (at least p<0.05) the effect of each extract on sperm motility and percentage of sperms with curved tail. Stem extract significantly decreased (p<0.01) the percentages of acephalic sperms and tailless head sperms. Diet-stem extract interaction significantly influenced (p<0.05) live-dead ratio. Our data suggest that orally administered aqueous extracts of C. australis generally enhanced the sperm morphology and characteristics of the male Wistar rat and that the stem extract maintained sperm morphology better than the seed extract. It also showed that the stem extract decreased live-dead ratio and that the efficacy of orally administered aqueous C. australis stem extract

Efficacy of silkworm (Bombyx mori L.) chrysalis oil as a lipid source in adult Wistar rats.

Science.gov (United States)

Mentang, Feny; Maita, Masashi; Ushio, Hideki; Ohshima, Toshiaki

2011-08-01

The effects of silkworm chrysalis oil, rich in n-3 α-linolenic acid (ALA), on lipid metabolism in Wistar rats were investigated. The rats were fed diets containing 7% soybean oil (control), silkworm chrysalis oil (SWO), or fish oil (FO) for 8weeks. Plasma triglyceride and glucose levels were significantly lower in the SWO group after 8weeks compared to the control and FO groups. The total cholesterol and blood urea nitrogen levels were higher in the control group than in the SWO and FO groups at 8weeks post-consumption. However, aspartate amino transferase and alanine amino transferase levels were not significantly different among all groups. A higher arachidonic acid (AA) content was detected in the control group, while lower AA levels were observed with the increase in EPA and DHA in the SWO and FO groups. These results suggest that n-3 α-linolenic acid-rich silkworm chrysalis oil can improve hyperlipidaemia and hyperglycaemia. Copyright © 2011 Elsevier Ltd. All rights reserved.

Economic impact assessment of Turkey's post-Kyoto vision on emission trading

International Nuclear Information System (INIS)

Akın Olçum, Gökçe; Yeldan, Erinç

2013-01-01

For the post-Kyoto period, Turkey strongly emphasizes the establishment of national emission trading system by 2015 and its integration with the EU ETS along its accession process to the EU. In this paper, we study the mechanisms of adjustment and economic welfare consequences of various ETS regimes that Turkey considers to apply by 2020, i.e. regional ETS and international trading within the EU ETS. We conduct our analysis under the current EU 20–20–20 emission target, 20%, and also under its revised version, 30%. We find that Turkey has economic gains from linking with the EU ETS under the 20% cap, in comparison to the domestic ETSs. Despite the EU's welfare loss under linkage in comparison to the case where Turkey has domestic abatement efforts, it still prefers linking as it increases economic well being compared to the case where Turkey does not abate. Under 30% cutback, Turkey has critical output loss under linkage due to high abatement burden on the EU, while the EU is better off as it passes some of its abatement burden to Turkey. Therefore, emission quotas and their allocation across the ETS and non ETS sectors become highly critical in distributing the overall economic gains from bilateral trading. - Highlights: • We conduct welfare analysis of Turkey's post-Kyoto vision on emission trading. • Welfare impacts of having Turkey in the EU ETS via EU accession are analyzed. • Analysis is done with the current EU target of 20%, and the revised target of 30%. • Welfare impacts of linkage on both regions highly depend on the emission targets. • The EU has welfare gains when Turkey engages in abatement actions

Kyoto and beyond : the low emission path to innovation and efficiency

International Nuclear Information System (INIS)

Torrie, R.; Parfett, R.; Steenhof, P.

2002-09-01

This paper presents a scenario in which greenhouse gas emissions in Canada are brought down to half the current levels over the next 28 years, surpassing the Kyoto target and putting Canada on a course for even greater emission reductions in the long term. The rationale for this action is based on information which states that concentration of greenhouses gases in the upper atmosphere will continue to increase until emissions are brought down to about half their current levels on a global basis. Just to stop emissions from growing on a global level would require a reduction of about 50 per cent in Canada. It is noted that achieving the Kyoto targets would not stop atmospheric concentrations of greenhouse gases from continuing to rise unless they are implemented with a plan to reduce emissions even further for the long term. The design principles that were followed in coming up with a plan to achieve 50 per cent emission reductions include: an energy demand focus; efficiency; renewable energy sources; energy services that are provided by technologies that are environmentally benign; energy services provided at least cost; and diversity of energy sources. It was concluded that the key to achieving sustainable reductions in greenhouse gas emissions is on the demand side of the energy economy, suggesting there is a need for basic changes in the climate policy debate in Canada. Studies have confirmed that technological innovation and energy saving measures can meet environmental objectives while creating economic growth and employment opportunities. It was suggested that these measures could provide economic renewal in regions that are in decline. They will also reduce air pollution which is becoming a major economic and public health issue in several Canadian communities. refs., tabs., figs

Paper presented to the Commission des transports et de l'environnement in the context of the general consultation concerning the implementation of the Kyoto Protocol in Quebec

International Nuclear Information System (INIS)

2003-02-01

Climate change is a major issue facing Quebec's population and future generations. The scientific community generally agrees on the negative effects resulting from global climate change on human health, the environment and the economy. In 1997, the Kyoto Protocol was adopted by industrialized countries, whereby countries agreed to reduce their emissions of greenhouse gases (GHG) by a certain percentage, calculated from 1990 levels. In the case of Canada, this percentage was 6 per cent, for the first commitment period covering 2008-2012. Quebec's performance on the issue of GHG emissions compares favorably to that of other Canadian provinces, even to that of other industrialized countries. Canada ratified the Kyoto Protocol in December 2002. The Quebec National Assembly called for a parliamentary committee to meet on 18 February 2003 on the implementation of the Kyoto Protocol. Hydro-Quebec, since 1997, has favored the ratification of the Kyoto Protocol by the Canadian government. In this document, Hydro-Quebec makes its position known in the context of this debate and the commercial context of the electric power industry in 2003. The first section of the document was devoted to the favorable performance of Hydro-Quebec, on the retroactive and prospective aspects of GHG emissions with regard to the entire electric power industry in Canada. In the second section, an explanation was provided, in the context of deregulation of the electricity market in North America, on the implementation of the Kyoto Protocol in Quebec and in Canada and how it becomes a major commercial issue for Hydro-Quebec. The analysis was conducted in light of the mandate of Hydro-Quebec to provide a secure and reliable service to its customers. refs., 1 fig

A new materials irradiation facility at the Kyoto university reactor

International Nuclear Information System (INIS)

Yoshiie, T.; Hayashi, Y.; Yanagita, S.; Xu, Q.; Satoh, Y.; Tsujimoto, H.; Kozuka, T.; Kamae, K.; Mishima, K.; Shiroya, S.; Kobayashi, K.; Utsuro, M.; Fujita, Y.

2003-01-01

A new materials irradiation facility with improved control capabilities has been installed at the Kyoto University Reactor (KUR). Several deficiencies of conventional fission neutron material irradiation systems have been corrected. The specimen temperature is controlled both by an electric heater and by the helium pressure in the irradiation tube without exposure to neutrons at temperatures different from the design test conditions. The neutron spectrum is varied by the irradiation position. Irradiation dose is changed by pulling the irradiation capsule up and down during irradiation. Several characteristics of the irradiation field were measured. The typical irradiation intensity is 9.4x10 12 n/cm 2 s (>0.1 MeV) and the irradiation temperature of specimens is controllable from 363 to 773 K with a precision of ±2 K

History of the research reactor institute of Kyoto University in view of nuclear science information data base (KURRIP)

Energy Technology Data Exchange (ETDEWEB)

Takeuchi, Takayuki; Mizuma, Mitsuo (Kyoto Univ., Kumatori, Osaka (Japan). Research Reactor Inst.); Kimura, Itsuro

1994-02-01

Since the Research Reactor Institute of Kyoto University was established as an inter-university research institute in 1963, a large number of cooperative research projects have been achieved by visiting scientists and its own staff in various research fields, making use of facilities centered around the Kyoto University Reactor, as well as the other experimental facilities. Ten years ago, the construction of the 'KURRIP' data base was initiated to grasp the whole aspect of the research activities at the Institute, in commemoration of its 20th anniversary. At the present time, KURRIP contains the information on 5,910 papers published for 29 years from 1963 to 1991. As this academic year is the 30th anniversary of the Institute, the history of its research activities was reviewed again using this data base. All of the publications were classified by authors's affiliations, kinds of papers, publishers, fields of studies, and research facilities used, and their historical variations are checked and discussed. (author).

Research project on accelerator-driven subcritical system using FFAG accelerator and Kyoto University critical assembly

International Nuclear Information System (INIS)

Mishima, Kaichiro; Unesaki, Hironobu; Misawa, Tsuyoshi; Tanigaki, Minoru; Mori, Yoshiharu; Shiroya, Seiji; Inoue, Makoto; Ishi, Y.; Fukumoto, Shintaro

2005-01-01

The KART (Kumatori Accelerator-driven Reactor Test facility) project started in Research Reactor Institute, Kyoto University in fiscal year 2002 with the grant by the Japanese Ministry of Education, Culture, Sports, Science and Technology. The purpose of this research project is to demonstrate the basis feasibility of accelerator driven system (ADS), studying the effect of incident neutron energy on the effective multiplication factor in a subcritical nuclear fuel system. For this purpose, a variable-energy FFAG (Fixed Field Alternating Gradient) accelerator complex is being constructed to be coupled with the Kyoto University Critical Assembly (KUCA). The FFAG proton accelerator complex consists of ion-beta, booster and main rings. This system aims to attain 1 μA proton beam with energy range from 20 to 150 MeV with a repetition rate of 120 Hz. The first beam from the FFAG complex is expected to be available by the end of FY 2005, and the experiment on ADS with KUCA and the FFAG complex (FFAG-KUCA experiment) will start in FY 2006. Before the FFAG-KUCA experiment starts, preliminary experiments with 14 MeV neutrons are currently being performed using a Cockcroft-Walton type accelerator coupled with the KUCA. Experimental data are analyzed using continuous energy Monte-Carlo codes MVP, MCNP and MNCP-X. (author)

Reactor laboratory course for students majoring in nuclear engineering with the Kyoto University Critical Assembly (KUCA)

International Nuclear Information System (INIS)

Nishihara, H.; Shiroya, S.; Kanda, K.

1996-01-01

With the use of the Kyoto University Critical Assembly (KUCA), a joint reactor laboratory course of graduate level is offered every summer since 1975 by nine associated Japanese universities (Hokkaido University, Tohoku University, Tokyo Institute of Technology, Musashi Institute of Technology, Tokai University, Nagoya University, Osaka University, Kobe University of Mercantile Marine and Kyushu University) in addition to a reactor laboratory course of undergraduate level for Kyoto University. These courses are opened for three weeks (two weeks for the joint course and one week for the undergraduate course) to students majoring in nuclear engineering and a total of 1,360 students have taken the course in the last 21 years. The joint course has been institutionalized with the background that it is extremely difficult for a single university in Japan to have her own research or training reactor. By their effort, the united faculty team of the joint course have succeeded in giving an effective, unique one-week course, taking advantage of their collaboration. Last year, an enquete (questionnaire survey) was conducted to survey the needs for the educational experiments of graduate level and precious data have been obtained for promoting reactor laboratory courses. (author)

Establishment of SHG-44 human glioma model in brain of wistar rat with stereotactic technique

International Nuclear Information System (INIS)

Hong Xinyu; Luo Yi'nan; Fu Shuanglin; Wang Zhanfeng; Bie Li; Cui Jiale

2004-01-01

Objective: To establish solid intracerebral human glioma model in Wistar rat with xenograft methods. Methods: The SHG-44 cells were injected into brain right caudate nucleus of previous immuno-inhibitory Wistar rats with stereotactic technique. The MRI scans were performed at 1 week and 2 weeks later after implantation. After 2 weeks the rats were killed and pathological examination and immunohistologic stain for human GFAP were used. Results: The MRI scan after 1 week of implantation showed the glioma was growing, pathological histochemical examination demonstrated the tumor was glioma. Human GFAP stain was positive. The growth rate of glioma model was about 60%. Conclusion: Solid intracerebral human glioma model in previous immuno-inhibitory Wistar rat is successfully established

Historical on the Norm Related to the CO{sub 2} Emission Integrated in the Protocol of Kyoto; Historico sobre la Normativa Relacionada con las Emisiones de CO{sub 2} Integrado en el Protocolo de Kyoto

Energy Technology Data Exchange (ETDEWEB)

Villadoniga, M.

2006-07-01

The United Nations Framework Convention on Climate Change (UNFCCC) was approved in 1992 to respond to the worl-wide concern about the warming of the planet. The primary target was the stabilization of the concentration of greenhouse gases in the atmosphere, in an attempt to reduce to the minimum the degradation of the environment caused by humans. By virtue of the Convention, the Parts2 are committed to reach their objectives in the reduction of the emissions. A Conference of the Parts was stablished to promote the effective application of the Convention. The third Conference of the Parts, celebrated in Kyoto (Japan, 1997) approved, by consensus, the denominated Kyoto Protocol, in which 39 developed countries and countries with economies in transition were committed to reduce their emissions of greenhouse gases between years 2008 and 2012 in a 5.2 global percent with respect to the 1990 levels. Three {sup f}lexibility mechanisms{sup w}ere stablished to help the Parts to reach their objectives: the emissions trading, the clean development mechanism and the joint implementation. Within the European Union (EU), a redistribution of the general objective among his States Members is allowed: {sup G}reenhouse gas emissions trading{sup .} (Author)

Do use the climate policy mechanisms of the Kyoto protocol.. An interview with Hartmut Grass, Hamburg

International Nuclear Information System (INIS)

Anon.

1999-01-01

The aspects discussed in this interview are of a global and national nature. The global aspects relate to the results of the UN conference in Kyoto in matters of the UN Framework Convention on Climate Change, and the national aspects relate to Germany's environmental and energy policy and the current situation in the context of global policy for greenhouse gas abatement. (orig./CB) [de

Submission under the United Nations framework convention on climate change and Kyoto protocol 2010. National inventory report for the German greenhouse gas inventory 1990-2008; Berichterstattung unter der Klimarahmenkonvention der Vereinten Nationen und dem Kyoto-Protokoll 2010. Nationaler Inventarbericht zum Deutschen Treibhausgasinventar 1990-2008

Energy Technology Data Exchange (ETDEWEB)

Strogies, Michael; Gniffke, Patrick (comps.)

2010-06-15

As a Party to the United Nations Framework on Climate Change (UNFCCC), since 1994 Germany has been obliged to prepare, publish and regularly update national emission inventories of greenhouse gases. In February 2005, the Kyoto Protocol entered into force. As a result, for the first time ever the international community of nations is required to implement binding action objectives and instruments for global climate protection. This leads to extensive obligations vis-a-vis the preparation, reporting and review of emissions inventories. As a result of Europe's own implementation of the Kyoto Protocol, via the adoption of EU Decision 280/20041, these requirements became legally binding for Germany in spring 2004. Pursuant to Decision 3/CP.5, all The purpose of such reports is to ensure the transparency, consistency and comparability of inventories and support the independent review process. The Secretariat of the Framework Convention on Climate Change has made submission of the inventory report a pre-requisite for performance of the agreed inventory reviews. Germany now presents its eighth National Inventory Report (NIR 2010), following its inventories for the years 1990 to 2008. This latest report covers the same period (1990 to 2008), and it describes the methods and the data sources on which the calculations are based. This year, the NIR contains, for the first time, an additional Part II, along with additional sub-chapters in the existing part, in conformance with expanded requirements under the Kyoto Protocol and the relevant decisions at the European level. Part I of the NIR presents, in Chapters 1 to 10, all the information relevant to the annual greenhouse gas inventory. Chapter 1 provides background information about climate change and about greenhouse gas inventories, as well as further information relative to the Kyoto Protocol. In addition, this chapter describes the basic principles and methods with which the emissions and sinks of the IPCC categories

Effects of Ascorbic Acid on Reproductive Functions of Male Wistar ...

African Journals Online (AJOL)

Effects of Ascorbic Acid on Reproductive Functions of Male Wistar Rats Exposed to Nicotine. ... smoke, and its effects on male reproductive system and fertility are well documented. ... The drugs were orally administered for thirty-five days.

Depressed glucose utilization in lungs of BB wistar spontaneously diabetic rats

International Nuclear Information System (INIS)

Uhal, B.D.; Moxley, M.A.; Longmore, W.J.

1986-01-01

Lungs of BB wistar spontaneously diabetic rats were perfused with [ 14 C(U)]glucose in modified Krebs Ringer bicarbonate medium for 1.5 hours. Lungs from non-diabetic BB Wistar rats were perfused simultaneously and served as controls. The perfusions were terminated by rapid freezing of the tissue in liquid N 2 followed by separation of surfactant and residual lung fractions. The rates of glucose incorporation into surfactant DSPC, PG, and PE were decreased 4.7, 2.4 and 2.5-fold, respectively, in lungs of spontaneously diabetic rats when expressed as final product specific activities. The rate of glucose incorporation into residual PC was also reduced by 2.3-fold. Expressed as moles incorporated per gram wet weight of lung, incorporations into surfactant DSPC, PG and residual PC were also reduced by 4.1, 6.3 and 3.8-fold respectively. These data; (1) agree with previous studies of the lungs of streptozotocin and alloxan-diabetic rats; (2) show that the depressed glucose utilization for lipid synthesis observed previously is not due to streptozotocin or alloxan toxicity; (3) suggest that the BB Wistar rat will provide a useful model for the study of the effects of insulin-dependent diabetes on lung metabolism

Approaching the Kyoto targets: a case study for Basilicata region (Italy)

Energy Technology Data Exchange (ETDEWEB)

Salvia, M.; Cuomo, V. [Consiglio Nazionale delle Ricerche, Tito Scalo (Italy). Istituto di Metodologie per l' Analisi Ambientale; Pietrapertosa, F. [Consiglio Nazionale delle Ricerche, Tito Scalo (Italy). Istituto di Metodologie per l' Analisi Ambientale; Universita degli Studi della Basilicata, Potenza (Italy). Dip. di Ingegneria e Fisica dell' Ambiente; Cosmi, C. [Consiglio Nazionale delle Ricerche, Tito Scalo (Italy). Istituto di Metodologie per l' Analisi Ambientale; Istituto Nazionale di Fisica della Materia, Napoli (Italy); Macchiato, M. [Universita Federico II, Napoli (Italy). Dip. di Scienze Fisiche

2004-02-01

Approaching the national Kyoto Protocol (KP) targets involves a re-definition of the actual configuration of local energy systems. This study deals with a local scale application of the IEA-MARKAL models generator, in which the anthropogenic system of Basilicata Region (Southern Italy) is investigated to support the definition of coherent long- term strategies and sound climate protection policies. A scenario by scenario analysis points out the behaviour of the optimal mix of fuels and technologies in the presence of carbon dioxide emissions constraints. Trade off curves and reduced costs analyses outline the most effective actions for contributing to the national KP targets, with particular emphasis on the interventions in Civil (Residential, Commercial and Services) and waste management sectors. (author)

Advances in multimedia modeling: 14th International Multimedia Modeling Conference, MMM 2008, Kyoto, Japan, January 9-11, 2008: Proceedings

NARCIS (Netherlands)

Satoh, S.; Nack, F.; Etoh, M.

2008-01-01

This book constitutes the refereed proceedings of the 14th International Multimedia Modeling Conference, MMM 2007, held in Kyoto, Japan, in January 2007. The 23 revised full papers and 24 revised poster papers were carefully reviewed and selected from more than 130 submissions. The papers are

Tracing of Zinc Nanocrystals in the Anterior Pituitary of Zinc-Deficient Wistar Rats.

Science.gov (United States)

Kuldeep, Anjana; Nair, Neena; Bedwal, Ranveer Singh

2017-06-01

The aim of this study was to trace zinc nanocrystals in the anterior pituitary of zinc-deficient Wistar rats by using autometallographic technique. Male Wistar rats (30-40 days of age, pre-pubertal period) of 40-50 g body weight were divided into the following: the ZC (zinc control) group-fed with 100 ppm zinc in diet, the ZD (zinc-deficient) group-fed with zinc-deficient (1.00 ppm) diet and the PF (pair-fed) group-received 100 ppm zinc in diet. The experiments were set for 2 and 4 weeks. Pituitary was removed and processed for the autometallographic technique. The control and pair-fed groups retained their normal morphological features. However, male Wistar rats fed on zinc-deficient diet for 2 and 4 weeks displayed a wide range of symptoms such as significant (P zinc nanocrystals in the nuclei. The present findings suggest that the dietary zinc deficiency causes decreased intensity of zinc nanocrystals localization and their distribution in the pituitary thereby contributing to the dysfunction of the pituitary of the male Wistar rats. The severity of zinc deficiency symptoms progressed after the second week of the experiment. Decreased intensity of zinc nanocrystals attenuates the pituitary function which would exert its affect on other endocrine organs impairing their functions indicating that the metabolic regulation of pituitary is mediated to a certain extent by zinc and/or hypothalamus-hypophysial system which also reflects its essentiality during the period of growth.

The Kyoto meeting has given a clear signal. The 3rd conference of signatory states to the UN Framework Convention on Climate Change: Current situation, negotiation dynamics, results; Kyoto-Gipfel hat deutliches Signal gesetzt. Die 3. VSK zur KRK: Ausgangslage, Verhandlungsdynamik, Ergebnis

Energy Technology Data Exchange (ETDEWEB)

Lamprecht, F.

1998-01-01

This third meeting of the Parties to the UN Framework Convention on Climate Change, held from 1-10 December 1997 in Kyoto/Japan, on which high expectations had been placed, just as on the Berlin meeting two years ago, has certainly not come up to expectations, but still agreed upon a Protocol that can be called an important signpost in international policy for protection of the environment. The envisaged greenhouse gas reduction by 5.2 per cent (of 1990 emissions) laid down in the Protocol, to be achieved by the industrialized countries either individually or by Joint Implementation over the period from 2008 until 2012, is a positive result considering the present situation. Although the agreed cutback falls short of the figures given by climate experts (who demand at least a 20% reduction by the year 2005), the obligation of the USA, the worldwide biggest emitter of greenhouse gases, to achieve a mandatory minimum cutback in emissions of 7% can be considered a big success. (orig./CB) [Deutsch] Auf der wie vor zwei Jahren in Berlin mit stark ueberzogenen Erwartungen ueberfrachteten 3. Vertragsstaatenkonferenz (VSK) zur Klimarahmenkonvention (KRK) vom 1.-10. Dezember 1997 in Kyoto/Japan ist ein zwar bescheidender, aber wichtiger Meilenstein der internationalen Umweltpoltik gesetzt worden. Die im Kyoto-Protokoll festgeschriebene, von den Industrielaendern individuell oder gemeinsam in der Periode 2008-2012 im Durchschnitt zu erzielende Treibhausgasreduktion von insgesamt 5,2% (Basis 1990) ist, gemessen an der Ausgangslage, positiv zu werten. Wenngleich damit die Forderung der Klimaforscher (mindestens 20%-Reduktion bis 2005) nicht erreicht wurde, muss die 7%-Minderungsverpflichtung des weltgroessten Treibhausgasemittenten USA als grosser Erfolg gesehen werden. (orig./RHM)

Studies of the effect of 0.4-Gy and 0.6-Gy prenatal X-irradiation on postnatal adult behavior in the Wistar rat.

Science.gov (United States)

Jensh, R P; Brent, R L; Vogel, W H

1987-02-01

Thirty-four pregnant Wistar rats were X-irradiated on the 9th or 17th day of gestation at a dosage level 0.4 Gy or 0.6 Gy or were sham-irradiated. All mothers were allowed to deliver their offspring, and litters were limited to a maximum of eight on day 2. On day 30, 224 offspring were weaned and raised until 60 days of age, at which time testing began. Each rat randomly received, in random order, three of the following six behavioral tests: Water T-maze, Conditioned Avoidance Response, Forelimb Hanging, Activity Wheel, Swimming, and Open Field. There were no statistically significant differences between the irradiated and control groups for maternal weight or weight gain or mean litter size, although the litter size of the 17th day 0.6-Gy group was slightly lower. Among offspring irradiated with 0.6 Gy on the 17th day, 3-day-old neonates' weights were significantly reduced. Offspring irradiated on the 17th day with 0.6 Gy exhibited higher Conditioned Avoidance Response 5th-day and retest avoidance scores than did the controls. There were also significant sex differences in responses within the irradiated and control groups for several tests, which were unrelated to radiation exposure. The results of this study indicate that low-level X-irradiation during the fetal period of rat gestation results in neonatal growth retardation and subtle behavioral alterations that may be manifested in adult life. Growth retardation may be the most sensitive indicator of subtle effects that result from low-level prenatal exposure to X-rays.

Studies of the effect of 0.4-Gy and 0.6-Gy prenatal X-irradiation on postnatal adult behavior in the Wistar rat

International Nuclear Information System (INIS)

Jensh, R.P.; Brent, R.L.; Vogel, W.H.

1987-01-01

Thirty-four pregnant Wistar rats were X-irradiated on the 9th or 17th day of gestation at a dosage level 0.4 Gy or 0.6 Gy or were sham-irradiated. All mothers were allowed to deliver their offspring, and litters were limited to a maximum of eight on day 2. On day 30, 224 offspring were weaned and raised until 60 days of age, at which time testing began. Each rat randomly received, in random order, three of the following six behavioral tests: Water T-maze, Conditioned Avoidance Response, Forelimb Hanging, Activity Wheel, Swimming, and Open Field. There were no statistically significant differences between the irradiated and control groups for maternal weight or weight gain or mean litter size, although the litter size of the 17th day 0.6-Gy group was slightly lower. Among offspring irradiated with 0.6 Gy on the 17th day, 3-day-old neonates' weights were significantly reduced. Offspring irradiated on the 17th day with 0.6 Gy exhibited higher Conditioned Avoidance Response 5th-day and retest avoidance scores than did the controls. There were also significant sex differences in responses within the irradiated and control groups for several tests, which were unrelated to radiation exposure. The results of this study indicate that low-level X-irradiation during the fetal period of rat gestation results in neonatal growth retardation and subtle behavioral alterations that may be manifested in adult life. Growth retardation may be the most sensitive indicator of subtle effects that result from low-level prenatal exposure to X-rays

Do foreign direct investment and renewable energy consumption affect the CO2 emissions? New evidence from a panel ARDL approach to Kyoto Annex countries.

Science.gov (United States)

Mert, Mehmet; Bölük, Gülden

2016-11-01

This study examines the impact of foreign direct investment (FDI) and the potential of renewable energy consumption on carbon dioxide (CO 2 ) emissions in 21 Kyoto countries using an unbalanced panel data. For this purpose, Environmental Kuznets Curve (EKC) hypothesis was tested using panel cointegration analysis. Panel causality tests show that there are significant long-run causalities from the variables to carbon emissions, renewable energy consumption, fossil fuel energy consumption and inflow foreign direct investments. The results of our model support the pollution haloes hypothesis which states that FDI brings in clean technology and improves the environmental standards. However, an inverted U-shaped relationship (EKC) was not supported by the estimated model for the 21 Kyoto countries. This means that economic growth cannot ensure environmental protection itself or environmental goals cannot await economic growth. Another important finding is that renewable energy consumption decreases carbon emissions. Based on the empirical results, some important policy implications emerge. Kyoto countries should stimulate the FDI inflows and usage of renewable energy consumption to mitigate the air pollution and meet the emission targets. This paper provides new insights into environment and energy policies through FDI inclusion.

Kerjasama Universitas Riau dan Universitas Kyoto dalam Pengelolaan Ekosistem Gambut di Kabupaten Bengkalis Tahun 2010-2014

OpenAIRE

", Afrizal; Al Husna, Hasma Al Husna

2015-01-01

This research explains about cooperation of Riau University and Kyoto University forward management of peatland ecosystem in District Bengkalis-Indonesia. The purpose of this research to know degradation of peatland ecosystem in District Bengkalis-Indonesia have global effect. A huge of peat area unwise exploited, especially for palm oil plantation industrial forest estate (plantation development: forestry and estate corps). This problem have of interest to the international institutions do r...

Kyoto, the oil sands and the GHG emissions market

International Nuclear Information System (INIS)

Vickers, P.

2004-01-01

This paper reviews uncertainties in the oil sands industry in relation to climate change, greenhouse gas emissions and the Kyoto Protocol. Other issues contributing to uncertainties in the industry were also discussed, including water and natural gas issues, refinery capacity and markets, price and exchange rates as well as capital availability and project cost overruns. The potential economic impact of the Kyoto Protocol on oil sands was outlined with prices per barrel. Government regulations were examined in the context of the evolving expectations of the Canadian public. U.S. actions on climate change were examined at the federal and state level. Emissions trading systems were reviewed with reference to a post 2012 regime. The 2005 budget was discussed, along with the Canadian legislative agenda and domestic offsets program, as well as the regulatory agenda in June of 2005. Post 2012 issues were examined, including discussions on the next commitment period, with reference to the fact that there was no support for new commitments among developing countries but that domestic pressures was building in the U.S. for air and climate regulations. Pressures from shareholders and the scientific community were discussed. Emissions trading in the European Union was reviewed. Stabilization goals will mean significant cuts to emissions in order to accommodate growth. Scenario planning and climate change uncertainties were also reviewed. The benefits of scenario planning in complex situations were outlined and were seen to encourage the development of strategic options. Issues concerning environmental stewardship and possible responses by the Unites States were discussed. Three scenarios were outlined: that climate change is not man-made and all the problems will go away; that technology will evolve to accommodate changes; and that policy will be insensitive to the economy, technology will lag and the energy sector will be faced with much higher costs. Various risk management

Testicular Morphometry and Histology of Male Wistar Rats and ...

African Journals Online (AJOL)

The effects of aqueous extract of Spondias mombin leaves on testicular characteristics and neonatal birth weights after oral treatment of male and female ... was no antifertility consequence of aqueous spondias mombin on the male wistar rat but insipient infertility was noticed with lower dosages for the female but none with ...

Radiofrequency electromagnetic radiation from cell phone causes defective testicular function in male Wistar rats.

Science.gov (United States)

Oyewopo, A O; Olaniyi, S K; Oyewopo, C I; Jimoh, A T

2017-12-01

Cell phones have become an integral part of everyday life. As cell phone usage has become more widespread, concerns have increased regarding the harmful effects of radiofrequency electromagnetic radiation from these devices. The current study was undertaken to investigate the effects of the emitted radiation by cell phones on testicular histomorphometry and biochemical analyses. Adult male Wistar rats weighing 180-200 g were randomly allotted to control, group A (switched off mode exposure), group B (1-hr exposure), group C (2-hr exposure) and group D (3-hr exposure). The animals were exposed to radiofrequency electromagnetic radiation of cell phone for a period of 28 days. Histomorphometry, biochemical and histological investigations were carried out. The histomorphometric parameters showed no significant change (p electromagnetic radiation of cell phone leads to defective testicular function that is associated with increased oxidative stress and decreased gonadotropic hormonal profile. © 2017 Blackwell Verlag GmbH.

Adult-Onset Hypothyroidism Enhances Fear Memory and Upregulates Mineralocorticoid and Glucocorticoid Receptors in the Amygdala

OpenAIRE

Montero-Pedrazuela, Ana; Fern?ndez-Lamo, Iv?n; Alieva, Mar?a; Pereda-P?rez, Inmaculada; Venero, C?sar; Guada?o-Ferraz, Ana

2011-01-01

Hypothyroidism is the most common hormonal disease in adults, which is frequently accompanied by learning and memory impairments and emotional disorders. However, the deleterious effects of thyroid hormones deficiency on emotional memory are poorly understood and often underestimated. To evaluate the consequences of hypothyroidism on emotional learning and memory, we have performed a classical Pavlovian fear conditioning paradigm in euthyroid and adult-thyroidectomized Wistar rats. In this ex...

Beneficial effects of low dose Musa paradisiaca on the semen quality of male Wistar rats.

Science.gov (United States)

Alabi, A S; Omotoso, Gabriel O; Enaibe, B U; Akinola, O B; Tagoe, C N B

2013-03-01

This study aimed at determining the effects of administration of mature green fruits of Musa paradisiaca on the semen quality of adult male Wistar rats. THE ANIMALS USED FOR THE STUDY WERE GROUPED INTO THREE: the control group, given 2 ml of double distilled water, a low dose group given 500 mg/kg/day and a high dose group given 1000 mg/kg/day of the plantain fruits, which was made into flour, and dissolved in 2 ml of double distilled water for easy oral administration. Significant increment in the semen parameters was noticed in animals that received a lower dose of the plantain flour, but those animals who received the high dose had marked and very significant reduction in sperm cell concentration and percentage of morphologically normal spermatozoa. Musa paradisiaca should be consumed in moderate quantities in order to derive its beneficial effects of enhancing male reproductive functions.

Effect of a trans fatty acid-enriched diet on biochemical and inflammatory parameters in Wistar rats.

Science.gov (United States)

Longhi, Rafael; Almeida, Roberto Farina; Machado, Letiane; Duarte, Maria Marta Medeiros Frescura; Souza, Débora Guerini; Machado, Priscila; de Assis, Adriano Martimbianco; Quincozes-Santos, André; Souza, Diogo Onofre

2017-04-01

Recent data regarding trans fatty acids (TFAs) have implicated these lipids as particularly deleterious to human health, causing systemic inflammation, endothelial dysfunction and possibly inflammation in the central nervous system (CNS). We aimed to clarify the impact of partially hydrogenated soybean oil (PHSO) with different TFA concentrations on cerebrospinal fluid (CSF), serum and hepatic parameters in adult Wistar rats. Wistar rats (n = 15/group) were fed either a normolipidic diet or a hyperlipidic diet for 90 days. The normolipidic and hyperlipidic diets had the same ingredients except for fat compositions, concentrations and calories. We used lard in the cis fatty acid group and PHSO in the trans fatty acid group. The intervention groups were as follows: (1) low lard (LL), (2) high lard (HL), (3) low partially hydrogenated soybean oil (LPHSO) and (4) high partially hydrogenated soybean oil (HPHSO). Body weight, lipid profiles and the inflammatory responses in the CSF, serum and liver tissue were analyzed. Surprisingly, with the PHSO diet we observed a worse metabolic response that was associated with oxidative stress in hepatic tissue as well as impaired serum and CSF fluid parameters at both PHSO concentrations. In many analyses, there were no significant differences between the LPHSO and HPHSO diets. Dietary supplementation with PHSO impaired inflammatory parameters in CSF and blood, induced insulin resistance, altered lipid profiles and caused hepatic damage. Overall, these findings suggest that fat composition is more important than the quantity of fat consumed in terms of cis and trans fatty acid diets.

Morphological evaluation of the superior colliculus of young Wistar ...

African Journals Online (AJOL)

Morphological evaluation of the superior colliculus of young Wistar rats following prenatal exposure to Carica papaya leaf extract. ... 9 and 10 of gestation (Group A); days 16 and 17 (Group B); and on days 9, 10, 16 and 17 (Group C); while Group D represented the control, and received distilled water throughout gestation.

Sodium arsenite-induced reproductive toxicities in male Wistar rats ...

African Journals Online (AJOL)

Sodium arsenite-induced reproductive toxicities in male Wistar rats: role of Tridax procumbens leaf extract. ... Bulletin of Animal Health and Production in Africa ... In the present study, the effects of ethanol leaf extract of Tridax procumbens ... in Groups B to D as compared to Group A was significantly reduced (p<0.05).

The effect of tobacco snuff on blood coagulation parameters in adult ...

African Journals Online (AJOL)

This study evaluates the effect of tobacco snuff on platelet count, prothrombin time (PT), and partial thromboplastin time (aPTT) in adult Wistar rats weighing between 150-300g and divided into four group (A - D; n=12 each). Group A served as control, while B, C and D served as test groups. The test groups were further ...

Achilles tendon of wistar rats treated with laser therapy and eccentric exercise

Directory of Open Access Journals (Sweden)

Maria Verônica de Souza

2015-10-01

Full Text Available ABSTRACTIntroduction:Both laser therapy and eccentric exercises are used in tendon injuries. However, the association of these physiotherapeutic modalities is yet little investigated.Objective:To evaluate the effect of low-level laser therapy associated to eccentric exercise (downhill walking on Achilles tendinopathy of Wistar rats.Method:Eighteen Achilles tendon from 15 adult male Wistar rats were used. Tendons were distributed in six groups (laser, eccentric exercise, laser and eccentric exercise, rest, contralateral tendon, and healthy tendon. Unilateral tendinopathy was surgically induced by transversal compression followed by scarification of tendon fibers. The treatments laser therapy (904 nm, 3J/cm² and/or eccentric exercise (downhill walking; 12 m/min; 50 min/day; 15o inclination treadmill began 24 hours after surgery and remained for 20 days. Clinical and biomechanical analyzes were conducted. Achilles tendon was macroscopically evaluated and the transversal diameter measured. Euthanasia was performed 21 days after lesion induction. Tendons of both limbs were collected and frozen at -20°C until biomechanical analysis, on which the characteristic of maximum load (N, stress at ultimate (MPa and maximum extension (mm were analyzed.Results:Swelling was observed within 72 hours postoperative. No fibrous adhesions were observed nor increase in transversal diameter of tendons. Animals with the exercised tendons, but not treated with laser therapy, presented lower (p=0.0000 locomotor capacity. No difference occurred be-tween groups for the biomechanical characteristics maximum load (p=0.4379, stress at ultimate (p=0.4605 and maximum extension (p=0.3820 evaluated, even considering healthy and contralateral tendons.Conclusion:The concomitant use of low-level laser and the eccentric exercise of downhill walking, starting 24 hours after surgically induced tendinopathy, do not result in a tendon with the same biomechanical resistance or elasticity

Effects of the administration of a catalase inhibitor into the fourth cerebral ventricle on cardiovascular responses in spontaneously hypertensive rats exposed to sidestream cigarette smoke

OpenAIRE

Valenti, Vitor E.; Abreu, Luiz Carlos de; Fonseca, Fernando L. A.; Adami, Fernando; Sato, Monica A.; Vanderlei, Luiz Carlos M.; Ferreira, Lucas Lima; Rodrigues, Luciano M.; Ferreira, Celso

2013-01-01

OBJECTIVE: Previous studies have demonstrated a relationship between brain oxidative stress and cardiovascular regulation. We evaluated the effects of central catalase inhibition on cardiovascular responses in spontaneously hypertensive rats exposed to sidestream cigarette smoke. METHODS: Male Wistar Kyoto (WKY) rats and spontaneously hypertensive rats (SH) (16 weeks old) were implanted with a stainless steel guide cannula leading into the fourth cerebral ventricle (4...

Mécanisme pour un Développement Propre (MDP) du Protocole de Kyoto :barrières et opportunités pour les pays moins avancés d’Afrique. Cas du Burundi/Clean Development Mechanism (CDM) of the Kyoto Protocol: barriers and opportunities for the least developed countries in Africa. Case study of Burundi.

OpenAIRE

Bisore, Simon

2012-01-01

Du Protocole de Kyoto est née une série d’objectifs de réduction des émissions de GES. Le respect de ces objectifs peut entraîner des coûts très lourds pour les économies des pays développés engagés dans la lutte contre les changements climatiques. Pour minimiser les coûts imposés par ces objectifs, des instruments économiques ont été développés, avec notamment la création de marchés du carbone. Y participent les trois mécanismes de flexibilité du Protocole de Kyoto parmi lesquels figure le M...

Methylphenidate and Atomoxetine-Responsive Prefrontal Cortical Genetic Overlaps in "Impulsive" SHR/NCrl and Wistar Rats.

Science.gov (United States)

Dela Peña, Ike; Dela Peña, Irene Joy; de la Peña, June Bryan; Kim, Hee Jin; Shin, Chan Young; Han, Doug Hyun; Kim, Bung-Nyun; Ryu, Jong Hoon; Cheong, Jae Hoon

2017-09-01

Impulsivity, the predisposition to act prematurely without foresight, is associated with a number of neuropsychiatric disorders, including attention-deficit/hyperactivity disorder (ADHD). Identifying genetic underpinnings of impulsive behavior may help decipher the complex etiology and neurobiological factors of disorders marked by impulsivity. To identify potential genetic factors of impulsivity, we examined common differentially expressed genes (DEGs) in the prefrontal cortex (PFC) of adolescent SHR/NCrl and Wistar rats, which showed marked decrease in preference for the large but delayed reward, compared with WKY/NCrl rats, in the delay discounting task. Of these DEGs, we examined drug-responsive transcripts whose mRNA levels were altered following treatment (in SHR/NCrl and Wistar rats) with drugs that alleviate impulsivity, namely, the ADHD medications methylphenidate and atomoxetine. Prefrontal cortical genetic overlaps between SHR/NCrl and Wistar rats in comparison with WKY/NCrl included genes associated with transcription (e.g., Btg2, Fos, Nr4a2), synaptic plasticity (e.g., Arc, Homer2), and neuron apoptosis (Grik2, Nmnat1). Treatment with methylphenidate and/or atomoxetine increased choice of the large, delayed reward in SHR/NCrl and Wistar rats and changed, in varying degrees, mRNA levels of Nr4a2, Btg2, and Homer2, genes with previously described roles in neuropsychiatric disorders characterized by impulsivity. While further studies are required, we dissected potential genetic factors that may influence impulsivity by identifying genetic overlaps in the PFC of "impulsive" SHR/NCrl and Wistar rats. Notably, these are also drug-responsive transcripts which may be studied further as biomarkers to predict response to ADHD drugs, and as potential targets for the development of treatments to improve impulsivity.

Adolescent D-amphetamine treatment in a rodent model of ADHD: Pro-cognitive effects in adolescence without an impact on cocaine cue reactivity in adulthood.

Science.gov (United States)

Jordan, Chloe J; Taylor, Danielle M; Dwoskin, Linda P; Kantak, Kathleen M

2016-01-15

Attention-deficit/hyperactivity disorder (ADHD) is comorbid with cocaine abuse. Whereas initiating ADHD medication in childhood does not alter later cocaine abuse risk, initiating medication during adolescence may increase risk. Preclinical work in the Spontaneously Hypertensive Rat (SHR) model of ADHD found that adolescent methylphenidate increased cocaine self-administration in adulthood, suggesting a need to identify alternatively efficacious medications for teens with ADHD. We examined effects of adolescent d-amphetamine treatment on strategy set shifting performance during adolescence and on cocaine self-administration and reinstatement of cocaine-seeking behavior (cue reactivity) during adulthood in male SHR, Wistar-Kyoto (inbred control), and Wistar (outbred control) rats. During the set shift phase, adolescent SHR needed more trials and had a longer latency to reach criterion, made more regressive errors and trial omissions, and exhibited slower and more variable lever press reaction times. d-Amphetamine improved performance only in SHR by increasing choice accuracy and decreasing errors and latency to criterion. In adulthood, SHR self-administered more cocaine, made more cocaine-seeking responses, and took longer to extinguish lever responding than control strains. Adolescent d-amphetamine did not alter cocaine self-administration in adult rats of any strain, but reduced cocaine seeking during the first of seven reinstatement test sessions in adult SHR. These findings highlight utility of SHR in modeling cognitive dysfunction and comorbid cocaine abuse in ADHD. Unlike methylphenidate, d-amphetamine improved several aspects of flexible learning in adolescent SHR and did not increase cocaine intake or cue reactivity in adult SHR. Thus, adolescent d-amphetamine was superior to methylphenidate in this ADHD model. Copyright © 2015 Elsevier B.V. All rights reserved.

Selenite cataract and its attenuation by vitamin E in wistar rats.

Directory of Open Access Journals (Sweden)

Mathew Joe

2003-01-01

Full Text Available Purpose: To study the role of vitamin E in preventing cataract formation in experimental animals. Methods: An experimental model (selenite cataract was selected for this study. Selenite cataract was produced in rats by subcutaneous administration of sodium selenite. Biochemical and histological changes following induction of selenite cataract in weanling wistar rats were studied vis-à-vis the role of vitamin E in attenuating or preventing cataractogenesis. Results: Vitamin E was capable of preventing selenite cataractogenesis. Selenite cataract did not develop in 91.6% (11 of 12 and 76.7% (8 of 12 vitamin E treated rats, when administered on the 12th and 10th post partum day respectively. Conclusion: The study confirmed that selenite induced cataract in wistar rats is attenuated by vitamin E.

Fiscal 1998 achievement report on welfare technosystem research and development. Kyoto; 1998 nendo walfare technosystem kenkyu kaihatsu (Kyoto) seika hokokusho

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-03-01

To be ready for the computing-everywhere age to come, it is necessary to create environments in which the barrier-free utilization is ensured of various apparatuses of the daily routine, such as various bodily function substituting apparatuses capable of compensating for the degraded functions of disabled or aged individuals. Under the circumstances, a system for building man-machine interfaces in the home or the like is required, and fundamental technologies of architecture and information infrastructure have to be established on which the development of technologies for the field involved will proceed. Concerning the technologies already in existence in this field of research, a survey is conducted of the status of research and development of information interface techniques primarily at Stanford University, and a report is made thereon. Also reported is the information obtained at Technology and Persons with Disabilities Conference 1999. The result of a survey of the trend of research and development of the smart house under the TIDE (Technology Initiative for Disabled and Elderly People) project and the result of a survey of an information standardization project for equipment control in Europe are reported, and the result of a survey of the approach of Kyoto's welfare apparatus distributors to the development of equipment is made known. (NEDO)

To implicate the private sector in funding: The Kyoto mechanisms and SUMO policies

International Nuclear Information System (INIS)

Leguet, Benoit; Morel, Romain

2015-01-01

Internationally set objectives in the fight against climate change cannot be reached without funding from the private sector. Public money, a scarce resource, must be used as best possible, in particular when it has a leverage effect on private funding. In this respect, feedback from the Kyoto Protocol's clean development mechanism is of interest. On the eve of the 2015 Paris Climate Conference, we must ramp up the mobilization of private resources. Smart unconventional monetary (SUMO) policies could help us toward this goal. Several countries have adopted such policies to cope with macro-economic circumstances or systemic risks. Is the destabilization of the climate not a risk of this sort?

Political realities and economic realities towards a Kyoto protocol

International Nuclear Information System (INIS)

Bourdaire, J.M.

1997-01-01

The current climate change commitments and the negotiating positions of Annex I countries were discussed. It was pointed out that the energy sector is not homogeneous and therefore, climate change should focus on the areas all over the world which are most sensitive to a carbon value. It was also noted that while the present time is ripe for action on climate change, actions should not take place at any cost. A scenario based on the three principal functions of energy, i.e. to supply mobility, electricity and heat was proposed. It was claimed that this proposal had the potential to bridge the gap between the political reality of Kyoto and the economic realities of the energy sector. The essence of the proposal centred around the concept of 'carbon value'. The effect of establishing carbon values for each of the different energy services worldwide, was discussed. Various mechanisms for establishing carbon values, such as emission trading, joint implementation with non-Annex I parties, penalties for non-compliance, mitigation efforts in least-cost options, were also reviewed

Fulfilling the Kyoto protocol in Spain: A matter of economic crisis or environmental policies?

International Nuclear Information System (INIS)

Zafrilla, Jorge Enrique; López, Luis Antonio; Cadarso, María Ángeles; Dejuán, Óscar

2012-01-01

In 2008, Spain exceeded by 20.9% the CO 2 emissions allowed by the Kyoto Protocol for 2012. The financial and economic crisis has transformed these figures: as production fell so did energy demand and with it CO 2 emissions. Will the Spanish economic crisis allow Spain to fulfill its commitments? With this in mind, we have developed an extended input–output model able to forecast energy demand and compute CO 2 emissions linked to the consumption of energy goods: petroleum products, gas and coal. The results show that the crisis, and in particularly, the stagnation of the construction industry, is only one of the pillars which help to contain these emissions at −6.81%. The possibility of incorporating environmental policies, new technologies and increases in the price of crude oil in these simulations, means an even greater reduction of emissions than the impact of the crisis (−9.76%). The final result of our most pessimistic/realistic scenario is that, in 2012, Spain will exceed its CO 2 emissions, linked to the combustion of energy goods, by only 0.9%. - Highlights: ► We use an extended input–output model to forecast the evolution of CO 2 emissions. We evaluate the economic crisis impact on emissions figures (2008–2012). ► The environmental policies are introduced by considering structural trends. ► In our reference scenario, Spain exceeds Kyoto commitments only by 0.9% in 2012. ► The 16.6% emissions reduction is explained by trends (−9.8%) and crisis (−6,8%).

Assessment of Polyscias fruticosa (L. Harm (Araliaceae leaf extract on male fertility in male Wistar rats

Directory of Open Access Journals (Sweden)

ALEX BOYE

2018-03-01

Full Text Available Background: Polyscias fruticosa is used widely as food, disease remedy and as an ornamental across Afro-Asian countries. For instance, P. fruticosa is used traditionally as an anti-asthma, anti-tussive, and a muco-suppressant herbal remedy for asthmatics in Ghana. Although many studies have investigated the pharmacological basis of the ethnobotanical uses of P. fruticosa, however, its effect on the reproductive system remains completely unknown. Aim of study: This study assessed effects of Polyscias fruticosa leaf extract (PFE on male fertility and toxicity in adult male Wistar rats. Materials and methods: after crude preparation of PFE, it was subjected to qualitative phytochemical, thin layer chromatography (TLC and gas chromatography mass spectrometry (GC-MS analyses. Effect of PFE was assessed on male fertility and toxicity by using healthy adult male Wistar rats. Rats were randomly assigned to: normal saline (5 ml/kg po, n = 5, Clomiphene Citrate (50 mg/kg po; n = 5 and PFE (100, 200 and 500 mg/kg po; n = 5 respectively groups and treated for 21 days. On day 22 rats were sacrificed and male fertility parameters (left testis weight, relative testis weight, caudal epididymal weight, caudal epididymal sperm count, sperm motility, sperm morphology and assessment of male sex hormones and testicular histology were assessed. Results: There were no significant changes in bodyweight, weight of left testis, weights of right and left caudal epididymides between treatments groups (PFE and clomiphene citrate and control. Caudal epididymal sperm count increased in PFE (100 and 500 mg/kg-treated rats relative to control. Sperm motility relatively increased in PFE-treated rats compared to control. Sperm abnormality decreased in PFE-treated rats; especially in PFE (100 mg/kg group compared to control. Serum testosterone levels decreased inversely with serum luteinizing hormone (LH levels in PFE-treated rats compared to control. There were minimal

Implementing the Kyoto protocol in Europe: Interactions between international and Community controls

International Nuclear Information System (INIS)

Tabau, Anne-Sophie

2011-07-01

This bibliographical note presents a book which discusses the coexistence of the Kyoto protocol and of a regional regime within the European Union for the actual application of rules requiring mechanisms of control. The international regime implements a continuous monitoring which combines conventional techniques and more intrusive procedures. The European Community introduced a non-contentious mechanism with a large and strong law basis and sanction ability. The author assesses the ability of the monitoring system as a whole to ensure the very credibility of the Protocol. She also assesses the reliability of international and community economic tools which aim at reducing greenhouse gas emissions at a minimum cost. She also discusses the desirable evolutions of the regime of struggle against climate changes

Age-related differences in anxiety-like behavior and amygdalar CCL2 responsiveness to stress following alcohol withdrawal in male Wistar rats.

Science.gov (United States)

Harper, Kathryn M; Knapp, Darin J; Park, Meredith A; Breese, George R

2017-01-01

Behavioral and neuroimmune vulnerability to withdrawal from chronic alcohol varies with age. The relation of anxiety-like behavior to amygdalar CCL2 responses following stress after withdrawal from chronic intermittent alcohol (CIA) was investigated in adolescent and adult rats. Adolescent and adult Wistar rats were exposed to CIA (three 5-day blocks of dietary alcohol separated by 2 days of withdrawal) at concentrations that created similar blood alcohol levels across age. Twenty-four hours into the final withdrawal, half of the rats were exposed to 1 h of restraint stress. Four hours post-stress, rats were used for behavior or tissue assays. Anxiety-like behavior was increased versus controls by CIA in adolescents and by CIA + stress in adults. CCL2 mRNA was increased versus controls by CIA in adolescents and by CIA and CIA + stress in adults. CCL2 co-localization with neuronal marker NeuN was decreased versus controls by CIA in adolescents and by CIA + stress in adults. CCL2 co-localization with astrocytic marker GFAP was decreased versus controls by CIA and CIA + stress in adolescents, but experimental groups did not differ from controls in adults. CCL2 co-localization with microglial marker Iba1 was decreased versus controls by stress alone in adolescents and by CIA + stress in adults. Changes in CCL2 protein might control behavior at either age but are particularly associated with CIA alone in adolescents and with CIA + stress in adults. That the number of CeA neurons expressing CCL2 was altered after CIA and stress is consistent with CCL2 involvement in neural function.

A review of research activities at the Research Reactor Institute of Kyoto University in view of research publication information

International Nuclear Information System (INIS)

Takeuchi, Takayuki; Mizuma, Mitsuo; Kimura, Itsuro.

1995-01-01

A database of research publication was constructed for the purpose of grasping all of the research activities at the Research Reactor Institute, Kyoto University. The database named KURRIP collects all of the research publications of the Institute by not only its own staff but also visiting scientists. The publications are in the form of original papers, review papers, papers in proceedings, short notes and letters, synopses over 3 pages presented orally at scientific meeting, books and doctoral theses. At present, the KURRIP database contains the information on 6,210 items which have been published for 30 years since the Institute was established as an interuniversity research institute for joint use of a research reactor and other related large facilities in 1963. By utilizing the KURRIP database, the analyses have been done: (1) affiliation of the authors, (2) kind of publications, (3) classification of publishers, (4) research fields, and (5) experimental facilities. The KURRIP database is now stored in the Data Processing Center of Kyoto University and can be utilized through a computer center at one of the main national universities in Japan. (author)

Effects of chronic treatment with fluvoxamine and paroxetine during adolescence on serotonin-related behavior in adult male rats.

NARCIS (Netherlands)

Jong, T.R. de; Snaphaan, L.J.A.E.; Pattij, T.; Veening, J.G.; Waldinger, M.D.; Cools, A.R.; Olivier, B.

2006-01-01

Selective Serotonin Reuptake Inhibitors (SSRIs) are designed to treat adults, but are increasingly prescribed for adolescents. SSRIs might cause permanent changes in serotonin-related behavior in adolescents, since their serotonergic system is still developing. Male Wistar rats were treated with

Correlation between movement complexity during static standing and balance function in institutionalized older adults

Directory of Open Access Journals (Sweden)

Yamagata M

2017-03-01

Full Text Available Momoko Yamagata,1 Tome Ikezoe,1 Midori Kamiya,1 Mitsuhiro Masaki,2,3 Noriaki Ichihashi1 1Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, 2Department of Physical Therapy, 3Institute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, Japan Purpose: Sample entropy (SampEn is an analysis to evaluate movement complexity of the center of pressure (COP. A lower value of SampEn indicates lower complexity of COP variability, that is, rigidity, and lower degrees of freedom. Previous studies reported the association of increased SampEn with improved standing balance ability in young subjects. However, no studies have examined these relationships among older adults. Thus, we aimed to investigate the relationship between SampEn and standing balance ability in older adults.Subjects and methods: The subjects were 33 institutionalized older adults (aged 82.2±6.5 years. COP during static standing was measured. The standard deviation (SD values of COP and SampEn in the sagittal and frontal planes were calculated using time series data. One-leg standing test (OLST, functional reach (FR test, and lateral reach (LR test were also measured to evaluate standing balance ability.Results: OLST, FR, and LR were 6.5±8.3 s, 19.8±5.9 cm, and 18.2±6.4 cm, respectively. Pearson correlation analysis revealed that SampEn in the sagittal plane significantly correlated with OLST (r=-0.35 and FR (r=-0.36. However, SampEn in the frontal plane and SD of COP in both sagittal and frontal planes had no relationship with any of the clinical balance tests.Conclusion: Lower SampEn implies rigidity for postural control. In the present study, it was found that lower SampEn in the sagittal plane was related to a higher balance function, which suggests that older adults utilized body rigidity to maintain postural stability as a compensative strategy. Keywords: older adults, posture, balance, standing, complexity

Sub-chronic oral toxicity of Cuminum cyminum L.'s essential oil in female Wistar rats.

Science.gov (United States)

Taghizadeh, Mohsen; Ostad, Seyed Naser; Asemi, Zatollah; Mahboubi, Mohaddese; Hejazi, Sara; Sharafati-Chaleshtori, Reza; Rashidi, Aliakbar; Akbari, Hosein; Sharifi, Nasrin

2017-08-01

The current study was performed to evaluate the toxicity of Cuminum cyminum L. (C. cyminum)'s essential oil after 23 days and 45 days of repeated oral administration in female Wistar rats. A total of 80 healthy female Wistar rats were randomly selected and divided into 4 groups. The rats were gavaged with C. cyminum's essential oil at dose levels of 0, 250, 500 and 1000 mg/kg/day. Clinical signs, body weight, hematology, serum biochemistry and organ histopathology were assessed once after 23 days and again after 45 days passed from the start of the intervention. Oral administration of C. cyminum's essential oil had no observed adverse effects on clinical signs, mortality, body weight, hematology, biochemistry and organ histology (liver, kidneys, spleen and lungs) in a sample of healthy female Wistar rats after 23 days and 45 days from the start of the study. However, an increase in serum levels of alanine transaminase (ALT) was found only at dose level of 1000 mg/kg/d C. cyminum's essential oil, after the 23-days interval. We conservatively defined the non-observed adverse effect level (NOAEL) for C. cyminum's essential oil as 500 mg/kg/d in female Wistar rats. The present study results should be treated with cautious in terms of the other organs' toxicity. Copyright © 2017 Elsevier Inc. All rights reserved.

A low-carbon scenario creation method for a local-scale economy and its application in Kyoto city

International Nuclear Information System (INIS)

Gomi, Kei; Shimada, Kouji; Matsuoka, Yuzuru

2010-01-01

On May 2008, Kyoto city government set up a low-carbon target of a 50% GHG reduction by 2030 compared to the 1990 level. To contribute to these discussions, we developed a local (city-scale) low-carbon scenario creation method. An estimation model was developed to show a quantitative and consistent future snapshot. The model can explicitly treat the uncertainty of future socio-economic situations, which originate from the openness of local economy. The method was applied to Kyoto city, and countermeasures to achieve the low-carbon target were identified. Without countermeasures, emissions would increase 12% from 2000. Among the measures, the reduction potential of energy efficiency improvements to residential and commercial sectors was found to be relatively large (15% and 18% of total reductions, respectively). The reduction potential of the passenger transport sector, in which the city government's policy is especially important, was 17% of the total amount. A sensitivity analysis showed that a 10% increase in exports leads to an 8.5% increase in CO 2 emissions, and a 20% increase in the share of the commuters from outside the city leads to a 3.5% decrease of CO 2 emissions because of the smaller number of residents in the city.

Muusikamaailm : Gergievi festival Rotterdamis. Los Angelese Ooper alustas. Luzerni festival tänaseni. Yaltah Menuhin lahkunud. Kyoto auhind György Ligetile / Priit Kuusk

Index Scriptorium Estoniae

Kuusk, Priit, 1938-

2001-01-01

Rotterdami Filharmoonikute peadirigendi V. Gergijevi korraldatud muusikafestivalist. Los Angelese Ooperi hooaja algusest. Luzerni festivalist šveitsis. Lühidalt Yaltah Menuhinist. G. Ligeti pälvis Kyoto elutöö-auhinna

Effect of a hyper-protein diet on Wistar rats development and ...

African Journals Online (AJOL)

STORAGESEVER

2009-05-04

May 4, 2009 ... studied possible presence of anti milk-protein seric IgG induced by the .... when administrating long term hyper-protein diets for humans. Reactivity to the ... adipose tissue without major side effects in Wistar male rats. Am. J.

Differences in tubuloglomerular feedback--oscillatory activity between spontaneously hypertensive and Wistar-Kyoto rats

DEFF Research Database (Denmark)

Holstein-Rathlou, N H; Leyssac, P P

1985-01-01

strains, oscillations could be elicited by free flow microperfusion with artificial tubular fluid. When furosemide was added to the artificial tubular fluid in a concentration of 0.1 mmol/l, the oscillations were abolished in both strains of rats. It is concluded that, in both strains of rats...

Effect of Massoia (Massoia aromatica Becc.) Bark on the Phagocytic Activity of Wistar Rat Macrophages

OpenAIRE

Triana Hertiani; Agustinus Yuswanto; Sylvia Utami Tunjung Pratiwi; Harlyanti Muthma’innah Mashar

2018-01-01

The essential oil of Massoia (Massoia aromatica Becc., Lauraceae) bark is a potential immunomodulator in vitro. This study evaluated the potential immunomodulatory effects of Massoia bark infusion on the nonspecific immune response (phagocytosis) of Wistar rats. For the in vitro assay, macrophages were treated with the freeze-dried infusion at the concentrations of 2.5, 5, 10, 20, or 40 µg/mL media. For the in vivo assay, two-month-old male Wistar rats were divided into five groups. The...

Effect of Low Dose Lead (Pb) Administration on Tail Immersion Test and Formalin-induced Pain in Wistar Rats: Possible Modulatory Role of Cobalt (II) Chloride.

Science.gov (United States)

Umar, A H; Suleiman, I; Muhammed, H

2017-03-06

Lead (Pb) is cheap and there is a long tradition of its use, but its toxic effects have also been recognized. There is increased public health concern regarding the hazards of low dose Pb exposure to adults and children. Studies have shown the risks for hypertension, decrements in renal function, subtle decline in cognitive function, and adverse reproductive outcome at low blood Pb level. In this study, the possible modulatory role of cobalt (II) chloride (CoCl2) on low level Pb exposure on tail immersion test and formalin induced pain was investigated. Twenty adult Wistar rats of both sexes (weight 150g to 200g) were used. The animals were divided into four groups (n = 5) and administered Pb (5mg/kg), Pb (5mg/kg) + CoCl2 (50mg/kg) and CoCl2 (50mg/kg) orally for twenty-eight days. The last group served as control and were given distilled water only. In the tail immersion test, there was no significant change in reaction time for all three groups when compared to the control. In the formalin-induced pain, pain score after five and forty-five minutes also do not show significant change for all the three groups when compared to control. This work suggested that exposure to 5mg/kg Pb for twenty-eight days do not significantly impair reaction time in tail immersion test and pain score in formalin induced pain in Wistar rats. Also, administration of 50mg/kg CoCl2 do not improve performance of the animals in the experiments.

Effects of aspartame on the evaluation of electrophysiological responses in Wistar albino rats

Directory of Open Access Journals (Sweden)

Arbind Kumar Choudhary

2016-07-01

Full Text Available Aspartame is a non-nutritive sweetener that is used predominantly in various ‘diet’ and ‘low-calorie’ products, such as beverages, instant breakfasts, desserts, breath mints, sugar-free chewing gum, vitamins, and pharmaceuticals, consumed by millions of people who are attempting weight loss, young adults and diabetic persons. On a weight basis, the metabolism of aspartame generates approximately 50% phenylalanine, 40% aspartic acid and 10% methanol. The detailed mechanisms of the effects of aspartame on the electrophysiological response are still unclear; therefore, this study was designed to clarify whether longer-term aspartame consumption has any effect on the electrophysiological response in Wistar albino rats. The oral administration of aspartame in a safe dose of 40 mg/kg bodyweight/day (as recommended by EFSA, 2012 was tested in Wistar albino rats for a longer period (90 days. Electrophysiological responses, including heart rate variability (HRV and electroencephalogram (EEG pattern, were assessed in a folate-deficient animal model along with control animals using BIOPAC and EEG equipment (model RMS EEG–24 brain new-plus: RMS – Recorder and Medicare systems. In this study, the folate-deficient animal model was used to mimic human methanol metabolism in rats. After 90 days of aspartame treatment, a significant alteration was observable in the time domain [Mean RR (ms SDNN (ms RMSSD (ms PNN50 (%] and the frequency domain [LF, HF, and LF/HF ratio] with significantly impaired frequency and amplitude of the fronto-parietal and occipital EEG waves at p ≤ 0.05. The results of this study clearly indicate that the oral consumption of aspartame reduced HRV, with sympathetic dominance and loss of vagal tone, and altered sympathovagal activity along with impairment of learning and memory, showing an additional effect on health within this study duration. The aspartame metabolites methanol and formaldehyde may be the causative factors

Abatement costs of post-Kyoto climate regimes

International Nuclear Information System (INIS)

Elzen, Michel den; Lucas, Paul; Vuuren, Detlef van

2005-01-01

This article analyses the abatement costs of three post-Kyoto regimes for differentiating commitments compatible with stabilising atmospheric greenhouse gases concentrations at 550 ppmv CO 2 equivalent in 2100. The three regimes explored are: (1) the Multi-Stage approach assumes a gradual increase in the number of Parties involved who are adopting either emission intensity or reductions targets; (2) the Brazilian Proposal approach, i.e. the allocation or reductions based on countries' contribution to temperature increase; (3) Contraction and Convergence, with full participation in convergence of per capita emission allowances. In 2050, the global costs increase up to about 1% of the world GDP, ranging from 0.5% to 1.5%, depending on baseline scenario and marginal abatement costs. Four groups of regions can be identified on the basis of similar costs (expressed as the percentage of GDP). These are: (1) OECD regions with average costs; (2) FSU, the Middle East and Latin America with high costs; (3) South-East Asia and East Asia (incl. China) with low costs; and (4) South Asia (incl. India) and Africa with net gains from emissions trading for most regimes. The Brazilian Proposal approach gives the highest costs for groups 1 and 2. The distribution of costs for the Contraction and Convergence approach highly depends on the convergence year. The Multi-Stage approach and Contraction and Convergence (convergence year 2050) seem to result in relatively the most even distribution of costs amongst all Parties

The carrying out process of Kyoto Protocol in Italy. Methods, scenarios and policy evaluation; Il processo di attuazione del Protocollo di Kyoto in Italia. Metodi, scenari e valutazione di politiche e misure

Energy Technology Data Exchange (ETDEWEB)

Menna, P.; Tosato, G.C.; Parenti, A.; Santi, F.; Simbolotti, G.; Presutto, M.; Dalla Costa, M.; Colosimo, A. [ENEA, Rome (Italy); Bonanni, P.; Contaldi, M.; De Lauretis, R. [Agenzia Nazionale per la Protezione dell' Ambiente, Rome (Italy)

2000-07-01

This paper reports some technical contributes related to the Kyoto Protocol and its application in Italian decision making policy. [Italian] Il presente volume raccoglie una decina di contributi tecnici originariamente preparati o commissionati dall'ENEA, Ente Nazionale per le Nuove Tecnologie, l'Energia e l'Ambiente, in vista della Conferenza Nazionale Energia e Ambiente. Questa fotografia di una situazione in rapida evoluzione e' stata preparata da esperti del settore che contribuiscono a redigere il materiale tecnico di base utilizzato dai negoziatori nazionali durante le trattative internazionali e dai responsabili nazionali per avviare il processo di presa di decisioni in materia.

Effect of Prosthechea karwinskii (Orchidaceae on obesity and dyslipidemia in Wistar rats

Directory of Open Access Journals (Sweden)

Alejandra Rojas-Olivos

2017-12-01

Conclusions: The P. karwinskii extracts evaluated here reduces the glycemic and lipidemic parameters in Wistar rats with MS induced. These effects may be attributed to the high antioxidant capacity of the extracts.

Proceedings of the 18th technical meeting on nuclear reactor and radiation for KURRI engineers and the 9th technical official group section 5 meeting in Kyoto University

International Nuclear Information System (INIS)

2010-03-01

This report is a summary of 18th Technical Meeting on Nuclear Reactor and Radiation for KURRI Engineers in Kyoto University. This was also the 9th meeting for technical official group section 5 (nuclear and radiation) in Kyoto University. In the workshop, three special lectures held were: (1) 'On Border Between Subcritical and Supercritical', (2) 'Memories of Nuclear Power Plant Management for 40 Years', and (3) 'Introduction of Technical Office in Faculty of Engineering, Kyoto University'. The technical presentations held were: (1) 'Radiation Background Study of Specialty Products in Senshu Region', (2) 'Introduction of Radioactivation Analysis at KUR', (3) 'Consideration of Critical Approach Method for KUR Low-Enrichment Fuel Reactor Core Using SRAC', (4) 'Evaluation of Temperature Coefficient of KUR Low-Enrichment Fuel Reactor Core Using SRAC'. As training for technical staffs in Technical Office, we visited the facility in Ashiu Research Forest. An introduction of this facility and the comments from the participants were included in this report. (S.K.)

A study on characteristics and sources of winter time atmospheric aerosols in Kyoto and Seoul using PIXE and supplementary analysis

International Nuclear Information System (INIS)

Ma, C.-J.; Kasahara, M.; Tohno, S.; Yeo, H.-G.

1999-01-01

Atmospheric aerosols were collected using a two stages filter sampler to classify into the fine and coarse fraction in Kyoto and Seoul in winter season. Elemental concentrations of aerosols were analyzed by PIXE and EAS as well as ion concentrations by IC. Analyzed data were used to source of aerosol particles. (author)

Moderate exercise during pregnancy in Wistar rats alters bone and body composition of the adult offspring in a sex-dependent manner.

Directory of Open Access Journals (Sweden)

Brielle V Rosa

Full Text Available Exercise during pregnancy may have long-lasting effects on offspring health. Musculoskeletal growth and development, metabolism, and later-life disease risk can all be impacted by the maternal environment during pregnancy. The skeleton influences glucose handling through the actions of the bone-derived hormone osteocalcin. The purpose of this study was to test the effects of moderate maternal exercise during pregnancy on the bone and body composition of the offspring in adult life, and to investigate the role of osteocalcin in these effects. Groups of pregnant Wistar rats either performed bipedal standing exercise to obtain food/water throughout gestation but not lactation, or were fed conventionally. Litters were reduced to 8/dam and pups were raised to maturity under control conditions. Whole body dual-energy x-ray absorptiometry, and ex vivo peripheral quantitative computed tomography scans of the right tibia were performed. At study termination blood and tissue samples were collected. Serum concentrations of fully and undercarboxylated osteocalcin were measured, and the relative expression levels of osteocalcin, insulin receptor, Forkhead box transcription factor O1, and osteotesticular protein tyrosine phosphatase mRNA were quantified. Body mass did not differ between the offspring of exercised and control dams, but the male offspring of exercised dams had a greater % fat and lower % lean than controls (p=0.001 and p=0.0008, respectively. At the mid-tibial diaphysis, offspring of exercised dams had a lower volumetric bone mineral density than controls (p=0.01 and in the male offspring of exercised dams the bone: muscle relationship was fundamentally altered. Serum concentrations of undercarboxylated osteocalcin were significantly greater in the male offspring of exercised dams than in controls (p=0.02; however, the relative expression of the measured genes did not differ between groups. These results suggest that moderate exercise during

Total lymphoid irradiation in the Wistar rat: technique and dosimetry

International Nuclear Information System (INIS)

Hoogenhout, J.; Kazem, I.; de Jong, J.

1983-01-01

The technical and dosimetric aspects of total lymphoid irradiation (TLI) in the Wistar rat were evaluated as part of a set-up to develop a new model for tumor xenotransplantation. Information obtained from anatomical dissections, radionuclide imaging of the spleen, lymphography and chromolymphography was used to standardize the localization portals cut out in a lead plate. The two portals encompassed the lymphoid tissue above and below the diaphragm. A specially designed masonite phantom was used to measure the dose distribution in the simulated target volumes. Ionization chamber dosimetery, thermoluminescence dosimetry and film densitometry were used for measuring exposure and absorbed dose. Irradiation was performed with 250 kV X rays (HVL 3.1 mm Cu). The dose rate was regulated by adjusting the treatment distance. The dose inhomogeneity measured in the target volumes varied between 80-100%. The side scatter dose to non target tissues under the shielded area between the two portals ranged between 20-30%. The technique and dosimetry of total lymphoid irradiation in Wistar rats are now standardized and validated and pave the way for tumor xenotransplantation experiments

The observance of the Kyoto Protocol on climate changes: stakes of the international control of compliance with commitments

International Nuclear Information System (INIS)

Maljean-Dubois, S.

2007-01-01

The author presents the conclusions of multidisciplinary research which has examined the relationship between the Kyoto protocol's observance mechanisms (control of compliance of commitments and sanction in case of non compliance) and the more conventional mechanisms of international conflict solving. It also examines the peculiar characteristics of these mechanisms, whether legal or not. Finally, the author examines the impact of the adopted procedure, and whether it is constraining

A design study on hyper-thermal neutron irradiation field for neutron capture therapy at Kyoto University Reactor

International Nuclear Information System (INIS)

Sakurai, Y.; Kobayashi, T.

2000-01-01

A study about the installation of a hyper-thermal neutron converter to a clinical collimator was performed, as a series of the design study on a hyper-thermal neutron irradiation field at the Heavy Water Neutron Irradiation Facility of Kyoto University Reactor. From the parametric-surveys by Monte Carlo calculation, it was confirmed that the practical irradiation field of hyper-thermal neutrons would be feasible by the modifications of the clinical collimator and the bismuth-layer structure. (author)

Regional costs and benefits of alternative post-Kyoto climate regimes: Comparison of variants of the Multi-stage and Per Capita Convergence regimes

NARCIS (Netherlands)

Vuuren DP van; Elzen MGJ den; Berk MM; Lucas P; Eickhout B; Eerens H; Oostenrijk R; KMD

2003-01-01

Deze studie verkent de technische, economische en milieu implicaties van verschillende zogenaamde post-Kyoto regimes voor de verdeling van regionale reductie doelstellingen die leiden tot stabilisatie van de broeikasgasconcentratie in de atmosfeer op 550 en 650 ppmv CO2-equivalenten (het S550e

Results of geophysical survey on Hanaore-fault in the Kyoto urban area; Butsuri tansa ni yoru Kyoto shigaichi ni okeru Hanaore danso chosa

Energy Technology Data Exchange (ETDEWEB)

Yoshioka, T. [Geological Survey of Japan, Tsukuba (Japan); Echigo, T. [Osaka Soil Test, Osaka (Japan); Toshioka, T.; Matsubara, Y. [Oyo Corp., Tokyo (Japan)

1997-05-27

This paper reports results of gravity survey and seismic survey using the shallow bed reflection method to identify distribution of the Hanaore fault in the Kyoto urban area. In the gravity survey, level differential structure caused by the fault was identified as an abrupt change in Bouger anomalous values. The continuity therefrom made the estimation possible on existence and positions of such faults as the Hanaore fault belonging to the Hanaore fault system, the Shishigaya fault, the Kaguraoka fault, and the Okazaki fault. The estimation as a result of the gravity survey include the following findings: the Hanaore fault runs from south of the Yoshidayama in the south-north direction; the distribution of the Okazaki fault has a level differential structure falling on the east side; the structure shows low Bouger anomaly distribution; and this area forms a rift valley belt. In the seismic survey using the shallow bed reflection method, no distinct reflection plane considered as the basement was verified because of influence from urban area noise. However, it was possible to estimate such an underground structure as a monoclinal fold from shapes of the reflection plane and the distribution depths. 7 refs., 5 figs.

Histological evaluation of the prefrontal cortex of infantile Wistar rats ...

African Journals Online (AJOL)

Primiparous Wistar rats were mated, and pregnancy was confirmed. A daily dose of 0.03 mg/kg of nicotine was administered intra-peritoneally to each treated rat for five consecutive days during their first two weeks of gestation. The rate of development and maturation of brain cells was reduced, as well as a reduction in the ...

Post-Kyoto policy implications on the energy system: A TIAM-FR long-term planning exercise

Energy Technology Data Exchange (ETDEWEB)

Selosse, Sandrine; Assoumou, Edi; Maizi, Nadia; Mazauric, Vincent

2010-09-15

The aim of this study is to discuss the long term analysis of post-Kyoto commitments, with the modelling tool ETSAP-TIAM-FR. Through the specification of CO2 mitigation targets scenarios covering the period 2000-2050, this analysis focuses on the effects of these carbon constraints on several indicators such as global and regional CO2 emissions, the cost of the climate policy, carbon marginal costs, the primary energy consumption and the energy mix. This paper compares global efforts of CO2 mitigation with the cost of carbon and finally discusses the development of CCS technologies.

The role of mammary gland on 131-I uptake by neonatal of wistar mice

International Nuclear Information System (INIS)

Darussalam, M.; Soedjono, I.; Ilyas, R.

1988-01-01

The aim of this investigation was to know the role of mammary gland of Wistar mice in transfering Iodine (I) to neonatal that fit in the role of I itself, and the degree of neonate need to I. Twenty four albino Wistar mouse post natal, were divided into 4 groups of six mouse for each, based on the interval observation. Each mice was given per oral 0.25 ml Na131-I with the activity of 300 uCi. The observation were pointed to tissues and organs such as: blood, liver, kidney, digestion cannal, tiroid gland, lymphe, mammary gland and urine; where as for neonatal: blood, kidney, digestion cannal, and the tiroid gland. The resuls show thet the high 131-I repentions were bound on tiroid gland (between 5.72 and 21.76 %) and on mammary gland (batween 9.30 and 21.90 %) of Wistar mice at lactation period in line with the increasing of mammary gland function and increasing the need of iodine for neonatal. In uptake of 131-I the thyroid gland of neonatal seemed superior compared to tissue or other neonatal organs. (author). 5 refs, 2 figs, 4 tabs

Radionecrosis attenuation in wistar rats with cutaneous application of quercetin; Atenuacao da radionecrose em ratos Wistar com aplicacao cutanea de quercetina

Energy Technology Data Exchange (ETDEWEB)

Alves, Nelson Mendes

2016-11-01

The increased incidence of cancer has been significant in recent decades in the world population, as confirmed by national and international institutions in the health area. The emergence of cancer is influenced, predominantly by genetic and environmental factors, being manifested more in the adult population. The main modalities for cancer treatment (radiotherapy, chemotherapy and surgery) may be used separately or in combination, depending on the type of cancer. Among the methods mentioned, radiation therapy is the one more broadly used for the treatment of patients, having an associated side effect called radiodermatitis, which has degrees of severity ranging from simple erythema to radionecrosis. The manifestation of radiodermatitis may occur during the treatment or after the radiotherapy sessions: both situations have great relevance in the patient's quality of life and social costs. One of the studied alternative therapies for attenuating the radionecrosis is the quercetin cutaneous application. One of the alternative therapies, studied to mitigate or eliminate the radionecrosis, is based on the topical application of quercetin. To evaluate the effectiveness of this mitigation, an animal model of radionecrosis was developed, to be used in Wistar rats. After in vitro studies, the quercetin concentrations and time of application were determined, reducing the number of animals, when in vivo experiments are carried out. With the topical application of 250 μ mol/L of quercetin, one hour prior to gamma irradiation, at a dose of 85 Gy, the side effects of radiation were minimized, avoiding the formation of radionecrosis. There was, also, a tendency to attenuate the wound area in the studied animals, compared to the irradiated animals without the quercetin application. (author)

Reactor Physics Experiments by Korean Under-Graduate Students in Kyoto University Critical Assembly Program (KUGSiKUCA Program)

International Nuclear Information System (INIS)

Pyeon, Cheol Ho; Misawa, Tsuyoshi; Unesaki, Hironobu; Ichihara, Chihiro; Shiroya, Seiji; Whang, Joo Ho; Kim, Myung Hyun

2006-01-01

The Reactor Laboratory Course for Korean Under-Graduate Students in Kyoto University Critical Assembly (KUGSiKUCA) program has been launched from 2003, as one of international collaboration programs of Kyoto University Research Reactor Institute (KURRI). This program was suggested by Department of Nuclear Engineering, College of Advanced Technology, Kyunghee University (KHU), and was adopted by Ministry of Science and Technology of Korean Government as one of among Nuclear Human Resources Education and Training Programs. On the basis of her suggestion for KURRI, memorandum for academic corporation and exchange between KHU and KURRI was concluded on July 2003. The program has been based on the background that it is extremely difficult for any single university in Korea to have her own research or training reactor. Up to this 2006, total number of 61 Korean under-graduate school students, who have majored in nuclear engineering of Kyunghee University, Hanyang University, Seoul National University, Korea Advanced Institute of Science and Technology, Chosun University and Cheju National University in all over the Korea, has taken part in this program. In all the period, two professors and one teaching assistant on the Korean side led the students and helped their successful experiments, reports and discussions. Due to their effort, the program has succeeded in giving an effective and unique course, taking advantage of their collaboration

Europe facing climate change - a border adjustment measure to prepare the after-Kyoto?

International Nuclear Information System (INIS)

Abbas, Mehdi; Sindico, Francesco

2012-01-01

Considering the different relationships between the trade framework and that of the struggle against climate change, the authors address the European Union (EU) environmental strategy within the perspective of a multilateral governance of climate changes for the after-Kyoto period. After having recalled what is at stake in a border adjustment measure and outlined the difficulties of implementation of a tax-based solution at a multilateral level, the authors present the available strategies for the EU. Then, they address the strategy based on trade liberalization as incentive to the struggle against climate changes. They discuss the derogation to standard rules and finally propose a governance system between the United Nations Framework Convention on Climate Change (UNFCCC or FCCC) and the WTO

Nuclear characteristics evaluation for Kyoto University Research Reactor with low-enriched uranium core

Energy Technology Data Exchange (ETDEWEB)

Nakajima, Ken; Unesaki, Hironobu [Kyoto University Research Reactor Institute, Kumatori-cho Sennan-gun Osaka (Japan)

2008-07-01

A project to convert the fuel of Kyoto University Research Reactor (KUR) from highly enriched uranium (HEU) to low-enriched uranium (LEU) is in progress as a part of RERTR program. Prior to the operation of LEU core, the nuclear characteristics of the core have been evaluated to confirm the safety operation. In the evaluation, nuclear parameters, such as the excess reactivity, shut down margin control rod worth, reactivity coefficients, were calculated, and they were compared with the safety limits. The results of evaluation show that the LEU core is able to satisfy the safety requirements for operation, i.e. all the parameters satisfy the safety limits. Consequently, it was confirmed that the LEU fuel core has the proper nuclear characteristics for the safety operation. (authors)

Characteristics of neutron irradiation facility and dose estimation method for neutron capture therapy at Kyoto University research reactor institute

International Nuclear Information System (INIS)

Kobayashi, T.; Sakurai, Y.; Kanda, K.

2001-01-01

The neutron irradiation characteristics of the Heavy Water Neutron Irradiation Facility (HWNIF) at the Kyoto University Research Reactor Institute (KIJRRI) for boron neutron capture therapy (BNCT), is described. The present method of dose measurement and its evaluation at the KURRI, is explained. Especially, the special feature and noticeable matters were expounded for the BNCT with craniotomy, which has been applied at present only in Japan. (author)

The impact of the Kyoto Protocol on the Quebec electricity market : business opportunities, protection of reference levels, and trading of emission credits

International Nuclear Information System (INIS)

Legault, R. F.

2003-01-01

Helimax Energy is a consulting company located in Montreal, Quebec specializing in wind energy on the national and international scene. In Canada, Helimax has worked (or is currently working) in seven provinces. To date, 96 contracts in renewable energy sources have been fulfilled throughout the world, of which 66 projects deal with wind energy. Several factors explain the growth of wind energy. These include a constant reduction of cost, Kyoto Protocol (environmental conscience), energy policies, social acceptance, technological maturity, reliability, and availability of funds to name a few. Europe is the world leader in the wind energy market. Canada represents a market ripe for expansion. The Kyoto Protocol was discussed and the relative value of carbon credits was examined with the help of a graph. The value of carbon credits remains marginal in the context of clean development mechanisms, unless a very polluting technology (in terms of carbon emissions) is replaced and the credit carbon cost is relatively high. tabs., figs

Effect of calcium bentonite on lipid parameters in Wistar albino rat ...

African Journals Online (AJOL)

The in vivo effect of Nigerian calcium bentonite clay on rat plasma cholesterol and triglyceride levels of Wistar albino rats was investigated. The rats were fed for a period of four weeks with varying concentrations of the bentonite clay, and the cholesterol and triglyceride levels determined using spectrophotometric methods.

THE ACTION OF AVOCADO OIL ON THE LIPIDOGRAM OF WISTAR RATS SUBMITTED TO PROLONGED ANDROGENIC STIMULUM.

Science.gov (United States)

de Souza Abboud, Renato; Alves Pereira, Vivian; Soares da Costa, Carlos Alberto; Teles Boaventura, Gilson; Alves Chagas, Mauricio

2015-08-01

the abuse of steroid hormones administered in chronic form may cause alterations in the lypidic profile, conveying na increase in the levels of LDL, and reduction in the levels of HDL. In average, 53.44% of the lypidic composition of the avocado core is composed of oleic acid (which is a phytosterol) and the study of the hypolipemiating effect of these substances has been performed aiming at the prevention and control of dislypidemias. to assess the potential hypolipemiant power of the avocado oil on the lypidogram of adult male Wistar rats submitted to prolonged androgenic hiperestimulation. twenty eight Wistar rats were divided in 4 groups of 7 animals: the control group (CG); Avocado Oil Group (AOG) fed with a staple based on Avocado Oil; Induced Grupo (IG); and the Induced Grupo fed with a staple based on Avocado Oil (AOIG). The inducing was performed through surgery to subcutaneously implant sillicon pellets suffed with 1 ml of testosterone propionate which were replaced at every 4 weeks. VLDL (AOIG: 28.14 ± 4.45; IG:36.83 ± 5.56 mg/ml); Triglicerides (AOIG: 140.07 ± 22.66; IG: 187.2 ± 27 mg/ml); HDL (AOIG: 40, 67 ± 1.2; GI: 35.09 ± 0.8; AOG: 32.31 ± 2.61 e CG: 32.36 ± 4.93 mg/ml) Testosterone (AOIG:1.42 ± 0.46; GI: 2.14 ± 0.88; AOG: 2.97 ± 1.34 e CG:1.86 ± 0.79 ng/ml). avocado Oil exerted a direct regulating effect on the lypidic profile, acting efficiently on animals submmited to androgenic stimulation through a prolonged period. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

Canada and the Kyoto Protocol: Fact Sheet No. 5 - Developing countries

International Nuclear Information System (INIS)

2000-11-01

This fact sheet acknowledges that global change affects developed and developing countries alike, and the fact that most developing countries do not have the human, financial and technical capacity to effectively address climate change issues without help from the industrialized nations. The fact sheet also puts Canada on record as being in agreement with the spirit of the Kyoto Protocol to encourage the participation of developing countries in global efforts to combat climate change and promote sustainable development and reaffirms Canada's willingness to provide financial and technical assistance to developing countries to enable them to play a meaningful part in this global effort. In this context, the fact sheet briefly describes the new Canada Climate Change Development Fund which has been set up to reduce the growth of GHG emissions and support carbon sink activities in developing countries, to strengthen the capacity of developing conuntries to reduce their vulnerability to adverse effects of climate change, and to participate in global efforts to combat them

Morfologia testicular de ratos Wistar obesos sedentários e submetidos a treinamento físico = Testicular morphology in obese and sedentary Wistar rats submitted to physical training

Directory of Open Access Journals (Sweden)

Ken Sekine Takashiba

2011-01-01

Full Text Available O objetivo deste trabalho foi avaliar morfologicamente os efeitos da dieta de cafeteria e o treinamento físico em esteira sobre o testículo de ratos Wistar. Ratos machos adultos foram divididos em grupos (sedentário-controle; sedentário-cafeteria; treinado-controle; e treinadocafeteria. Para comprovar a instalação da obesidade calculou-se o índice de Lee e o peso dos tecidos adiposos periepididimal e retroperitoneal. A análise testicular envolveu o peso da gônada e após processamento histológico e coloração por Hematoxilina-Eosina, os parâmetros de diâmetro tubular, altura do epitélio seminífero, identificação dos tipos celulares presentes nos túbulos seminíferos, contagem de células e rendimento geral da espermatogênese. O aumento significativo do Índice de Lee e do peso dos tecidos adiposos, nos grupos que receberam dieta de cafeteria, comprovou a instalação da obesidade e indicou ser este um modelo adequado para induzir obesidade experimental. Não houve efeito da dieta ou do treinamento sobre o peso testicular, diâmetro tubular e altura do epitélio seminífero não havendo também diferenças na organização histológica dos testículos e túbulos seminíferos. Após quantificação celular e cálculo dos índices mitótico e meiótico e da capacidade total de suporte das células de Sertoli, verificamos efeito positivo do treinamento físico, independente da dieta recebida, sobre o rendimento geral da espermatogênese.The aim of this study was to morphologically evaluate the effects of the cafeteria diet and physical training on the testicles of adult Wistar rats. Adult male rats were divided into groups (sedentary-control, sedentary-cafeteria, trained-control, and trainedcafeteriaIn order to state the obesity condition both the Lee index and the weight of retroperitoneal and periepididymal adipose tissues were calculated. The testicular analysis involved the gonad weight and after the histological processing

Chemopreventive effects of embelin and curcumin against N-nitrosodiethylamine/phenobarbital-induced hepatocarcinogenesis in Wistar rats.

Science.gov (United States)

Sreepriya, M; Bali, Geetha

2005-09-01

The effects of embelin (50 mg/kg/day), a benzoquinone derivative of Embelia ribes, and the effects of curcumin (100 mg/kg/day), the active principle of Curcuma longa, against N-nitrosodiethylamine (DENA)-initiated and phenobarbital (PB)-promoted hepatocarcinogenesis were studied in Wistar rats. They were able to prevent the induction of hepatic hyper plastic nodules, body weight loss, increase in the levels of hepatic diagnostic markers, and hypoproteinemia induced by DENA/PB treatment. Hence, results of our study suggest the possible chemopreventive effects of embelin (EMB) and curcumin (CUR) against DENA/PB-induced hepatocarcinogenesis in Wistar rats.

Proceedings of the International Symposium on Multiple-Valued Logic (13th) Held at Kyoto, Japan on May 23-25, 1983.

Science.gov (United States)

1983-05-01

would like to thank the members of the Organizing Committee of ISMVL-Japan, listed on page vii of this Proceedings, for their generous support. Hisashi ...8217 °. °- . ’. . 6% Organizing Commnittee I *Chairman: Hisashi Mine Department of Applied Mathematics and Physics Kcyoto University, Kyoto...Masayuki Kimura (Tohoku University, Japan) Tadahiro Kitahashi (Toyohashi University of Technology, Japan) Yoshiaki Koga (National Defense Academy, Japan

Differences in Monoamine Oxidase Activity in the Brain of Wistar and August Rats with High and Low Locomotor Activity: A Cytochemical Study.

Science.gov (United States)

Sergutina, A V; Rakhmanova, V I

2016-06-01

Monoamine oxidase activity was quantitatively assessed by cytochemical method in brain structures (layers III and V of the sensorimotor cortex, caudate nucleus, nucleus accumbens, hippocampal CA3 field) of rats of August line and Wistar population with high and low locomotor activity in the open fi eld test. Monoamine oxidase activity (substrate tryptamine) predominated in the nucleus accumbens of Wistar rats with high motor activity in comparison with rats with low locomotor activity. In August rats, enzyme activity (substrates tryptamine and serotonin) predominated in the hippocampus of animals with high motor activity. Comparison of August rats with low locomotor activity and Wistar rats with high motor activity (i.e. animals demonstrating maximum differences in motor function) revealed significantly higher activity of the enzyme (substrates tryptamine and serotonin) in the hippocampus of Wistar rats. The study demonstrates clear-cut morphochemical specificity of monoaminergic metabolism based on the differences in the cytochemical parameter "monoamine oxidase activity", in the studied brain structures, responsible for the formation and realization of goal-directed behavior in Wistar and August rats.

Voluntary physical exercise alters attentional orienting and social behavior in a rat model of attention-deficit/hyperactivity disorder.

Science.gov (United States)

Hopkins, Michael E; Sharma, Mita; Evans, Gretchen C; Bucci, David J

2009-06-01

The effects of voluntary physical exercise on attentional function and social behavior were examined in male and female spontaneously hypertensive rats (SHR), a commonly used animal model of attention-deficit/hyperactivity disorder (ADHD). Rats in the exercise groups had free access to a running wheel for 2 weeks and then all rats received nonreinforced presentations of a visual stimulus (light) during the 1st training session, followed by daily sessions in which the light was paired with food. Nonexercising male and female SHR rats exhibited more unconditioned orienting behavior than Wistar-Kyoto rats. SHRs also exhibited impaired conditioning when the light was paired with food. Exercise reduced orienting in female SHRs but not in male SHRs. In the social interaction task, nonexercising male and female SHRs interacted more with an unfamiliar rat than Wistar-Kyoto rats. Exercise reduced the number of social interactions in female SHRs but not male SHRs. There were no differences in general locomotor activity observed between the nonexercising and exercising SHRs. These data indicate that exercise may preferentially benefit female SHRs, and has implications for using exercise as an intervention for ADHD and for understanding sex differences in the effects of exercise on behavior. Copyright (c) 2009 APA, all rights reserved.

Evaluation of Glycemic and Lipid Profile of Offspring of Diabetic Wistar Rats Treated with Malpighia emarginata Juice

Directory of Open Access Journals (Sweden)

Sandra M. Barbalho

2011-01-01

Full Text Available Knowing that maternal diabetes is related to hyperglycemia and fetal hyperinsulinemia, which affect the lipid metabolism, the aim of this study was to evaluate the effects of Malpighia emarginata (acerola juice on the glycemic and lipid profile of offspring of diabetic and nondiabetic Wistar rats. The adult offspring of non-diabetic dams and of dams with severe streptozotocin-induced diabetes were divided into groups: G1, offspring (of control dams treated with water, G2, offspring (of diabetic dams treated with water, G3, male offspring (of control dams treated with acerola juice, and G4, male offspring (of diabetic dams treated with acerola juice. The offspring of diabetic dams treated with acerola juice showed significantly decreased levels of glucose, cholesterol, triglycerides, and increased HDL-c. The use of acerola juice is a potential strategy to aid in the prevention of DM and dyslipidemia and its complications or to act as an auxiliary in the treatment of these diseases.

RF source for proton linear accelerator in Kyoto University

International Nuclear Information System (INIS)

Iwashita, Yoshihisa

1987-01-01

Construction of a 433 MHz, 7 MeV proton linear accelerator is currently underway in Kyoto University under a three-year plan starting in 1986. The ion source, power source for it, RFQ main unit, WR2100 waveguide and a set of klystrons for RFQ were installed last year, or the first year of the plan, and the power source for the klystrons for RFQ, a set of klystrons for STL, DTL main unit, etc., are planned to be installed this year. Operation has not started yet because of the absence of the power source for the klystrons. Thus this report is focused on the considerations made in selecting the acceleration frequency of 433 MHz, specifications of the klystrons and the structure of the power sources for them. Based on considerations of the efficiency and cost of the accelerating tubes and RF sources to be used, the acceleration frequencies of 433.33 MHz and 1,300 MHz were adopted. The klystron selected is Litton L5773, which has a peak power output of 1.25 Mw, average power output of 75 kW, maximum pulse width of 2,000 μS and duty of 6 percent, and it consists of four cavities. The structure and characteristics of a klystron are also described. (Nogami, K.)

l=1 helical axis heliotron device in Kyoto university

International Nuclear Information System (INIS)

Nagasaki, K.; Sano, F.; Mizuuchi, T.; Hanatani, K.; Okada, H.; Obiki, T.

1999-01-01

Helical systems are an attractive candidate for magnetic fusion reactor. Recently, there has been great progress in theoretical research of three dimensional magnetic field structures, resulting in several kinds of confinement optimization being proposed for toroidal magnetic confinement system. For example, some sophisticated ideas have appeared on stage such as quasi-helical symmetry and quasi-isodynamic system. To find experimentally which way is the best Optimisation, a new helical axis heliotron device, so called 'Heliotron J', is under construction in the Institute of Advanced Energy, Kyoto University, Japan. In this conference, the basic concept and the present status will be presented. In the conventional plane axis helical system, it was difficult to have both good particle confinement and good MHD stability simultaneously. The goal of Heliotron J project is to clarify their compatibility in the spatial axis toroidal device. The best way for Optimising the helical magnetic field configuration will be explored by investigating the plasma response to the change in the field components. The main subjects for plasma experiment are: demonstration of the existence of good magnetic flux surfaces, reduction of neoclassical transport in collisionless regime, MHD Stabilisation in high β plasma, controllability of bootstrap current, good confinement of high energy particles

Anti-diabetic properties of rice-based herbal porridges in diabetic Wistar rats.

Science.gov (United States)

Senadheera, Senadheera Pathirannehelage Anuruddhika Subhashinie; Ekanayake, Sagarika; Wanigatunge, Chandanie

2014-10-01

The present study aims to investigate anti-hyperglycaemic, anti-hyperlipidaemic and toxic effects of long-term consumption of selected green leafy porridges in a streptozotocin-induced diabetic Wistar rat model. Porridges made with Asparagus racemosus Willd. (AR), Hemidesmus indicus (L) R. Br. W. T. Aiton (HI), Scoparia dulcis L. (SD) and coconut milk porridge (CM) were incorporated into diets of diabetic Wistar rats. Diabetic control (DM) and normal control groups (NC) were provided with standard rat diet. Fasting blood glucose (FBG), HbA1c , C reactive protein (CRP), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), liver enzymes and creatinine were measured. Feed and water intake among diabetic groups were significantly high when compared with those of NC (p  0.05). Among the diabetic groups, lowest TC (119 ± 20.6 mg/dL) and highest HDL-C (33 ± 6.3 mg/dL) were also detected in SD group. Alanine transaminase and creatinine were not significantly different (p > 0.05) among diabetic groups but significant when compared with those of NC. When compared with those of NC, aspartate transaminase levels were significantly (p < 0.05) high in SD, CM and DM groups. Body weight : liver weight and body weight : pancreas weight ratios and CRP were not significantly different among all groups. The study proved that SD porridge reduced weight loss, elicited hypoglycaemic and hypolipidaemic properties, and caused no toxicity in diabetes-induced Wistar rats. Copyright © 2014 John Wiley & Sons, Ltd.

Report of researches by common utilization of facilities in Kyoto University Research Reactor Institute, latter half of fiscal year 1982

International Nuclear Information System (INIS)

1983-01-01

The technical report of the Kyoto University Research Reactor Institute is published any time to immediately report on the results of the functional tests of various experimental facilities, the test results for the products made for trial, radiation control, the situation of waste treatment, the data required for research and experiment such as the reports of study meetings, the conspicuous results obtained amid researches, new processes, and the discussion on other papers and reports. In this report, the title, the names of reporters and the summary of 65 researches carried out by the common utilization of the facilities in the Kyoto University Research Reactor Institute are collected. The themes of the researches are such as Moessbauer spectroscopic study of ferrocene and its derivative iodides by I-129, decomposition of cadmium telluride during heat treatment, element distribution in resource living things and environmental substances produced in northern ocean, radioactivation analysis of trace elements in blood of tumor-bearing animals, radioactivation analysis of noble metal elements in geochemical samples, relaxation phenomena by gamma-gamma perturbation angle correlation, separation of components in Allende meteorite and their radioactivation analysis, measurement of cross section of Pa-231 (n, gamma) reaction and others. (Kako, I.)

Report of researches by common utilization of facilities in Kyoto University Research Reactor Institute, first half of fiscal year 1982

International Nuclear Information System (INIS)

1983-01-01

The technical report of the Kyoto University Research Reactor Institute is published any time to immediately report on the results of the functional tests of various experimental facilities, the test results for the products made for trial, radiation control, the situation of waste treatment, the data required for research and experiment such as the reports of study meetings, the conspicuous results obtained amid researches, new processes, and the discussion on other papers and reports. In this report, the title, the names of reporters and the summary of 47 researches carried out by the common utilization of the facilities in the Kyoto University Research Reactor Institute are collected. The themes of the researches are such as diffusion of impurities ion-implanted in silicon into natural oxide films, origin of igneous rocks by trace element distribution study, element distribution in black ore and its accompanying rocks and origin of black ore, reprocessing of molten salt fuel of thorium group, forerunning martensite transformation of Fe-Pt invar alloy, change of nucleic acid component to recoil tritium at cryogenic temperature, gamma irradiation effect of KC1 containing Pb 2+ , radiation effect on cadmium halide crystals and impurity metallic ions and others. (Kako, I.)

Adolescent Atomoxetine Treatment in a Rodent Model of ADHD: Effects on Cocaine Self-Administration and Dopamine Transporters in Frontostriatal Regions

Science.gov (United States)

Somkuwar, Sucharita S; Jordan, Chloe J; Kantak, Kathleen M; Dwoskin, Linda P

2013-01-01

Cocaine abuse and attention deficit/hyperactivity disorder (ADHD) are often comorbid. Preclinical research indicates that medial prefrontal (mPFC) and orbitofrontal (OFC) cortices are important neural substrates for both disorders. Using the spontaneously hypertensive rat (SHR) model of ADHD, we reported that adolescent treatment with the stimulant methylphenidate, a dopamine (DAT) and norepinephrine (NET) transporter inhibitor, enhanced cocaine self-administration during adulthood, and was associated with increased DAT function in mPFC. This study investigates the effects of atomoxetine ((R)-N-methyl-γ-(2-methylphenoxy)-benzenepropanamine hydrochloride) treatment, a selective NET inhibitor, during adolescence on cocaine self-administration and on DAT function and cell-surface expression in mPFC and OFC during adulthood. SHR acquired cocaine self-administration faster than Wistar–Kyoto and Wistar. Across cocaine doses, SHR earned more cocaine infusions and had higher progressive-ratio breakpoints than Wistar–Kyoto and Wistar, demonstrating that the SHR phenotype models comorbid ADHD and cocaine abuse. Prior atomoxetine treatment did not augment cocaine self-administration in SHR, but acquisition was enhanced in Wistar–Kyoto. No strain differences were found for DAT kinetic parameters or cellular localization in the vehicle controls. Atomoxetine did not alter DAT kinetic parameters or localization in SHR mPFC. Rather, atomoxetine decreased Vmax and DAT cell surface expression in SHR OFC, indicating that inhibition of NET by atomoxetine treatment during adolescence indirectly reduced DAT function and trafficking to the cell surface in OFC, specifically in the ADHD model. Thus, atomoxetine, unlike methylphenidate, does not enhance vulnerability to cocaine abuse in SHR and may represent an important alternative for teens with ADHD when drug addiction is a concern. PMID:23822950

Mental Health Problems among Undergraduates in Fukushima, Tokyo, and Kyoto after the March 11 Tohoku Earthquake.

Science.gov (United States)

Ishikawa, Shin-ichi; Motoya, Ryo; Sasagawa, Satoko; Takahashi, Takahito; Okajima, Isa; Takeishi, Yasuchika; Essau, Cecilia A

2015-06-01

On March 11, 2011, the Great East Japan Earthquake devastated the Tohoku region, which led to a tsunami and a nuclear disaster. While these three disasters caused tremendous physical damage, their psychological impact remains unclear. The present study evaluated traumatic responses, internalizing (i.e., anxiety and depression), and externalizing (i.e., anger) symptoms among Japanese young people in the immediate aftermath and 2.5 years later. A total of 435 undergraduates were recruited from universities in three differentially exposed regions: Fukushima, Tokyo, and Kyoto. They completed a set of questionnaires retrospectively (i.e., September to December 2013) to measure their traumatic responses, anxiety and depressive symptoms, functional impairment, and anger immediately after the disaster and 2.5 years later. Participants in Tokyo had the highest level of traumatic response and internalizing symptoms immediately after the earthquake, whereas those in Fukushima had significantly higher levels of trait anger, anger-in (holding one's anger in), and anger-out (expressing one's anger externally). In Kyoto, the levels of anxiety and depression after 2.5 years were significantly higher than they were immediately after the disasters. In conclusion, anger symptoms were high among young people who lived at or near the center of the disasters, while anxiety and depression were high among those who lived far away from the disasters. These findings suggest the importance of providing mental health services to young people who did not live near the disaster area as well as to those living in the directly affected area.

Rapid development of Leydig cell tumors in a Wistar rat substrain

NARCIS (Netherlands)

Teerds, K. J.; de rooij, D. G.; de Jong, F. H.; Rommerts, F. F.

1991-01-01

In 78% of the Wistar rats (substrain U) studied, spontaneous Leydig cell tumors developed between the ages of 12 and 30 months. The first signs of tumor development, in the form of nodules of Leydig cells, were already apparent in 1-month-old U-rats. These nodules of Leydig cells were found in all

COMENTARIOS SOBRE EL CONVENIO DE KYOTO PARA LA ARMONIZACIÓN Y SIMPLIFICACIÓN DE PROCEDIMIENTOS ADUANEROS

OpenAIRE

Araújo Segovia, Ramiro; Pontificia Universidad Javeriana

2005-01-01

En el ámbito internacional existe un convenio sobre facilitación de procedimientos aduaneros, llamado “Convenio de Kyoto para la armonización y simplificación de los regímenes aduaneros”.En algunas normas internas colombianas se hace referencia a ese convenio, pero no ha sido firmado por Colombia. Además, en algunos sectores aduaneros se lo suele mencionar como un referente a tener en cuenta por el gobierno cuando expida normas aduaneras.Sin embargo, sentimos que no ha habido ni divulgación n...

Crocin reduced acrylamide-induced neurotoxicity in Wistar rat through inhibition of oxidative stress

Directory of Open Access Journals (Sweden)

Soghra Mehri

2015-09-01

Conclusion: The administration of crocin markedly improved behavioral and histopathological damages in Wistar rats exposed to ACR. Reduction of oxidative stress can be considered as an important mechanism of neuroprotective effects of crocin against ACR-induced toxicity.

PREFACE: Beyond Kyoto - the necessary road

Science.gov (United States)

Margrethe Basse, Ellen

2009-03-01

The Beyond Kyoto conference in Aarhus March 2009 was organised in collaboration with other knowledge institutions, businesses and authorities. It brought together leading scientists, policy-makers, authorities, intergovernmental organisations, NGO's, business stakeholders and business organisations. The conference was a joint interdisciplinary project involving many academic areas and disciplines. These conference proceedings are organised in central and recurring themes that cut across many debates on climate change, the climatic challenges as well as the solutions. In the front there is a short presentation of the conference concept. Part I of the proceedings focuses on issues related to the society - covering climate policy, law, market based instruments, financial structure, behaviour and consumption, public participation, media communication and response from indigenous peoples etc. Part II of the proceedings concerns the scientific knowledge base on climate related issues - covering climate change processes per se, the potential impacts of projected climate change on biodiversity and adaptation possibilities, the interplay between climate, agriculture and biodiversity, emissions, agricultural systems, increasing pressure on the functioning of agriculture and natural areas, vulnerability to extreme weather events and risks in respect to sea-level rise etc. The conference proceedings committee consists of four professors from Aarhus University: Jens-Christian Svenning, Jørgen E Olesen, Mads Forchhammer and Ellen Margrethe Basse. Aarhus University's Climate Secretariat has had the overall responsibility for coordinating the many presentations, as well as the practical side of arranging the conference and supporting the publication of papers. As Head of the Climate Secretariat and Chair of Aarhus University's Climate Panel, I would like to thank everyone for their contribution. This applies both to the scientific and the practical efforts. Special thanks to

Dietary intake of ain-93 standard diet induces Fatty liver with altered hepatic fatty acid profile in Wistar rats.

Science.gov (United States)

Farias Santos, Juliana; Suruagy Amaral, Monique; Lima Oliveira, Suzana; Porto Barbosa, Júnia; Rego Cabral, Cyro; Sofia Melo, Ingrid; Bezerra Bueno, Nassib; Duarte Freitas, Johnatan; Goulart Sant'ana, Antônio; Rocha Ataíde, Terezinha

2015-05-01

There are several standard diets for animals used in scientific research, usually conceived by scientific institutions. The AIN-93 diet is widely used, but there are some reports of fatty liver in Wistar rats fed this diet. We aimed to evaluate the hepatic repercussions of the AIN-93 diet intake in Wistar rats. Forty newly-weaned 21-day-old male Wistar rats were fed either the AIN-93 diet or a commercial diet for either 1 month or 4 months. Weight gain, serum biochemistry, hepatic histology, and hepatic fatty acid profile were analyzed. Hepatic steatosis was observed, especially in the group fed the AIN-93 diet. Serum blood glucose, absolute and relative liver weight and hepatic levels of oleic, palmitoleic, stearic, and palmitic fatty acids were related to the observed steatosis, while lipidogram and serum markers of liver function and injury were not. AIN-93 diet induced acute hepatic steatosis in Wistar rats, which may compromise its use as a standard diet for experimental studies with rodents. The hepatic fatty acid profile was associated with steatosis, with possible implications for disease prognosis. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

Long-term outcomes after percutaneous coronary intervention for chronic total occlusion (from the CREDO-Kyoto registry cohort-2).

OpenAIRE

Yamamoto, Erika; Natsuaki, Masahiro; Morimoto, Takeshi; Furukawa, Yutaka; Nakagawa, Yoshihisa; Ono, Koh; Mitsudo, Kazuaki; Nobuyoshi, Masakiyo; Doi, Osamu; Tamura, Takashi; Tanaka, Masaru; Kimura, Takeshi

2013-01-01

Despite improving success rate of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) lesions, the clinical benefit of recanalization of CTO is still a matter of debate. Of 13, 087 patients who underwent PCI in the CREDO-Kyoto registry cohort-2, 1, 524 patients received PCI for CTO (CTO-PCI). Clinical outcomes were compared between 1, 192 patients with successful CTO-PCI and 332 patients with failed CTO-PCI. In-hospital death tended to occur less frequently in the succe...

Intestinal ion transport in rats with spontaneous arterial hypertension.

Science.gov (United States)

Lübcke, R; Barbezat, G O

1988-08-01

1. Ion balance, intestinal ion transport in vivo with luminal Ringer, and direct voltage clamping in vivo with luminal Ringer and sodium-free choline-Ringer were studied in young (40 days old) and adult (120 days old) spontaneously hypertensive rats (SHR) and age-matched normotensive controls (Wistar-Kyoto rats, WKY). 2. Faecal sodium output was significantly higher in SHR compared with WKY in both young (+67%) and adult (+43%) rats. 3. Small-intestinal sodium absorption was equal in young SHR and WKY, but significantly greater net sodium absorption was found in the ileum of adult SHR. In contrast, net sodium absorption was reduced from the colon of both young and adult SHR. 4. In adult SHR, the colonic transepithelial short-circuit current (Isc) and the transepithelial potential difference (PD) were significantly higher, whereas the transepithelial membrane resistance (Rm) was significantly lower than in WKY. There was an identical drop in Isc in both strains when luminal sodium was replaced by choline. These data cannot be explained by increased electrogenic cation (sodium) absorption in the SHR, but would favour chloride secretion. 5. It is suggested that in SHR membrane electrolyte transport abnormalities may also be present in the epithelial cells of the small and large intestine, as have been demonstrated already in blood cells by several investigators. The SHR may become an interesting experimental animal model for the study of generalized ion transport disorders.

Effect of Nitric Oxide Synthesis Blockade on the Morphology of Langerhans Islets in August and Wistar Rats with Acute Alloxan Diabetes.

Science.gov (United States)

Smirnova, E A; Michunskaya, A B; Terekhina, O L; Kobozeva, L P; Kruglov, S V; Belkina, L M; Pozdnyakov, O M

2015-06-01

Alloxan diabetes was modeled in August rats with high activity of the NO system and in Wistar rats, and the effects of NO system blockade (by a course treatment with L-NNA) on Langerhans islet β cells were studied in 15 days. The toxic effects of diabetes on the rat β cells and islets were similar: the content of active β cells in the islets decreased to 15-20%, the number of islets to 24-29% of control. A course of L-NNA reduced the β cell and islet death, in August cells greater than in Wistar: the number of islets in August rats was restored to 81%, in Wistar rats to 60% of initial level; the activity of β cells remained at the control level in the former and 2-fold lower than in the control in the latter. It seems that a less pronounced protective effect of L-NNA in Wistar rats was explained by excessive reduction of NO level essential for β cell regeneration.

[Contractile function of the heart and myocardium antioxidant system in rats of August and Wistar strains during ischemia and reperfusion].

Science.gov (United States)

Sazontova, T G; Belkina, L M; Zhukova, A G; Kirillina, T N; Arkhipenko, Iu V

2004-01-01

In August rats, local myocardial ischemia caused by 30-min occlusion of the coronary artery induced a slight depression of the contractile function of the heart; the latter was restored after 15-min reperfusion more rapidly than in Wistar rats. In August rats, the activities of antioxidant protection enzymes were lower than in Wistar rats. In comparison with Wistar rats, these enzyme activities were decreased in a lesser degree under ischemia and were restored in a greater degree under reperfusion. It may thus be concluded that the higher stability of antiradical protection parameters in August rats is one of the mechanisms responsible for the enhanced resistance of the heart to ischemia- and reperfusion-induced injuries.

Passive Immunization of Anti bZP3 (Zone Pellucida3 in Wistar Rat (Rattus novergicus and Mouse (Mus musculus

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Y. Pantiwati

2012-12-01

Full Text Available This study was aimed at comparing the influence of anti bZP3’s passive immunization on anti-anti bZP3’s titer and pregnancy level on Wistar rats and mice. This study employed factorial design experiment with completely randomized design. The first factor was immunogenic type. The treated rats were immunized with 100 L anti bZP3 in 100 L Complete Freund’s Adjuvant (CFA, while the treated mice were injected with 50 L anti bZP3 in 50 L CFA. Control Wistar rats and mice were immunized with CFA and Incomplete Freund’s Adjuvant (IFA without anti bZP3. The second factor was animal type. The third factor was the length of serum incubation, i.e. 38, 49, 63, 86, 100, and 126 d. Dot blot on the treated Wistar rats and mice showed positive response proven by blue gradation; pre-immune mice as well as control Wistar rats and mice showed negative response proven by white gradation. The highest antibody titer in treated mouse serum was shown in 63 d incubation. The pregnancy on treated mice, control mice and Wistar rat occurred 100% until day 126; while the failure percentage on the treated mice was 4.5%. The pregnancy on treated mice occurred in 86 d incubation (1 rat, 100 d incubation (1 rat, and 126 d incubation (3 rats. Effective passive immunization on similar hospes occurred until day 63; while different hospes was ineffective. Antibodi anti-bZP3 was potential as a contraception through passive immunization on similar hospes.

The Effect of Pistacia khynjuk on Humoral Immune System of Wistar Rats

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A Hadinia

2011-01-01

Full Text Available Introduction & Objective: Plants from the genus Pistacia family such as Pistacia atlantica, Pistacia vera and Pistacia khynjuk are considered as herbal medicines. Antibacterial and anti-inflammatory effects of these plants have been confirmed. The aim of the current study was to find the effect of Pistacia khynjuk on humoral immune system of Wistar rats. Materials & Methods: This is an experimental study which was conducted at Yasuj University of Medical Sciences in 2009. Forty male Wistar rats were randomly allocated into four groups of ten animals and orally received 10 mg/kg of the extract of nucleus, cutin and fruit of Pistacia khynjuk respectively, every day for two weeks. The control group received only placebo. Immuno-reactivity was induced using BCG vaccine (IP with Freund‘s complete adjuvant (CFA. The titer of IgG and IgM were measured after the treatment using ELISA method. Moreover, the cervical lymph nodes and spleen of animals were excised and the volume and density of the primary and secondary follicle was evaluated by steriology. The collected data were analyzed by the SPSS using one-way ANOVA. Results: The differences in the mean level of IgG and IgM between the treated and the control animals were not significant (p>.05. Also, the mean volume of the spleen and cervical lymph nodes of the first three groups in comparison with the control animals were not significant (p>.05. Conclusion: Findings of this study showed that the Pistacia khynjuk did not have any direct effect on the activity of humoral immune system and the increasing of antibody level among Wistar rats.

Comparison of the Kyoto Scale of Psychological Development 2001 with the parent-rated Kinder Infant Development Scale (KIDS).

Science.gov (United States)

Aoki, Sayaka; Hashimoto, Keiji; Ikeda, Natsuha; Takekoh, Makoto; Fujiwara, Takeo; Morisaki, Naho; Mezawa, Hidetoshi; Tachibana, Yoshiyuki; Ohya, Yukihiro

2016-05-01

The purpose of the study was to extend our understanding of the Kyoto Scale of Psychological Development (KSPD) by comparison with a parent-rated scale, the Kinder Infant Development Scale (KIDS). The participants of this study were 229 children aged 0-4, who were referred to the Developmental Evaluation Center of the National Center for Child Health and Development, due to a suspected developmental disorder/delay. The participants were divided into subgroups, depending on age and overall DQ. For each group separately, correlation analyses were conducted between the Developmental Quotient (DQ) of each KSPD domain and DQ of each KIDS subscale. For high DQ group, in all ages, the KSPD Postural-Motor (P-M) domain DQ demonstrated a high correlation with the KIDS Physical-Motor DQ, and at young ages, it was also found to be moderately or strongly associated with the KIDS Manipulation DQ. For high DQ group, the KSPD Cognitive-Adaptive (C-A) domain DQ was most consistently related to the KIDS Manipulation DQ, and was also moderately correlated with the KIDS Physical-Motor DQ, Receptive Language DQ, Social Relationship with Adults DQ, Discipline DQ, and Feeding DQ, depending on age. For high DQ group, the KSPD Language-Social (L-S) DQ most consistently showed a moderate or high correlation with the KIDS Receptive Language DQ and the Manipulation DQ, and also related to Physical-Motor DQ, Expressive Language DQ, Language Conception DQ, Social Relationship with Adults DQ, and Social Relationship with Children DQ for some age groups. The low DQ group demonstrated stronger relationships on many of the pairs of the DQ of a KSPD subdomain and the DQ of a KIDS subscale, regardless of the type of subdomains and subscales. For high DQ group, the KSPD P-M domain was consistently related to parent-reported physical/motor development, the C-A domain primarily reflected a child's fine motor skills and his/her ability to understand and follow verbal instructions provided by adults

Complying with the Kyoto Protocol under uncertainty: Taxes or tradable permits?

International Nuclear Information System (INIS)

Quirion, Philippe

2010-01-01

The Kyoto Protocol allocates tradable emission allowances (AAUs) to developed countries, but they are free to choose a set of policy instruments to comply with these targets. We compare two different policy instruments: a tax and purely domestic tradable permits, for the European Union, the US and Japan. Information on abatement costs and international permit price is imperfect and stems from nine global economic models. For a country party to the Protocol, the benefit of emission reduction is that it can sell more or has to buy less AAUs. We show that in this context, permits entail a slightly lower expected cost than a tax for the US and Japan, whereas both instruments yield an almost equal outcome for Europe. Applying Weitzman's framework (Prices vs. quantities, RES, 1974) in this context, we show the importance of the positive correlation between costs and benefits: technology shocks that lead to low abatement costs in one country generally lead to low abatement costs in other countries too, thereby leading to a low international permit price in the true-up period.

Present status of Kyoto University reactor research result data base KURRIP

International Nuclear Information System (INIS)

Takeuchi, Takayuki

1986-01-01

The construction of KURRIP data base was begun in 1982, and in 1983, the data base concerning the literatures published in five years from 1978 to 1982 was set up in the Kyoto University Large Computer Center, and it has become available generally. In fiscal year 1984, the data concerning the literatures published from 1974 to 1977 and in 1983 were added. Moreover in this fiscal year, the work is carried out to input the data concerning the literatures published from 1970 to 1973 and in 1984. The data retrievable at present are those for ten years from 1974 to 1983. The results of having retrieved these data about a number of items are reported in this paper. The classification according to the places of employment of authors, the classification according to the kinds of literatures, the classification according to the languages used, the classification according to the installations used, the classification according to the fields of research, and the classification according to the magazines which printed the data are reported. (Kako, I.)

Toxicity, distribution, and accumulation of silver nanoparticles in Wistar rats

International Nuclear Information System (INIS)

Espinosa-Cristobal, L. F.; Martinez-Castañon, G. A.; Loyola-Rodriguez, J. P.; Patiño-Marin, N.; Reyes-Macías, J. F.; Vargas-Morales, J. M.; Ruiz, Facundo

2013-01-01

The bactericidal effect of silver nanoparticles (SNP) has lead to their application in several products mainly in the medicine field. This study analyzed the distribution, accumulation, and toxicity in principal organs of Wistar rats exposed to SNP suspensions by oral administration. Two sizes of washed SNP (14 and 36 nm) were prepared, characterized, and redispersed in deionized water. Each suspension was administrated to Wistar rats by oral way for 55 days; after finishing this treatment time, rats were sacrificed by anesthesia overdose. Organs were collected, processed, and prepared; then, accumulation and concentrations of SNP were obtained using inductively coupled plasma mass spectrometry (ICP-MS). Toxicity was determined by clinical chemistry and hematology from blood samples in three different periods; light microscopy (LM) and scanning electron microscopy (SEM) were applied to evaluate histopathology in tissues. Silver concentrations were higher in small intestine, followed by kidney, liver, and brain. Clinical chemistry and hematology showed altered values in blood urea nitrogen, total proteins, and mean corpuscular hemoglobin, concentration values had statistical difference in both groups (14 and 36 nm) (p < 0.05). LM, SEM, ICP-MS, clinical chemistry, and hematology tests suggest that the administration way, concentration, shape, size, presentation, administration time of SNP used in this study, do not change significantly these values.

Toxicity, distribution, and accumulation of silver nanoparticles in Wistar rats

Energy Technology Data Exchange (ETDEWEB)

Espinosa-Cristobal, L. F.; Martinez-Castanon, G. A., E-mail: mtzcastanon@fciencias.uaslp.mx; Loyola-Rodriguez, J. P.; Patino-Marin, N. [UASLP, Doctorado Institucional en Ingenieria y Ciencia de los Materiales (Mexico); Reyes-Macias, J. F. [Facultad de Estomatologia de la Universidad Autonoma de San Luis Potosi, Maestria y Doctorado en Ciencias Odontologicas en el Area de Odontologia Integral Avanzada (Mexico); Vargas-Morales, J. M. [Av. Salvador Nava s/n, Zona Universitaria, Facultad de Ciencias Quimicas de la Universidad Autonoma de San Luis Potosi (Mexico); Ruiz, Facundo [Facultad de Ciencias de la Universidad Autonoma de San Luis Potosi (Mexico)

2013-06-15

The bactericidal effect of silver nanoparticles (SNP) has lead to their application in several products mainly in the medicine field. This study analyzed the distribution, accumulation, and toxicity in principal organs of Wistar rats exposed to SNP suspensions by oral administration. Two sizes of washed SNP (14 and 36 nm) were prepared, characterized, and redispersed in deionized water. Each suspension was administrated to Wistar rats by oral way for 55 days; after finishing this treatment time, rats were sacrificed by anesthesia overdose. Organs were collected, processed, and prepared; then, accumulation and concentrations of SNP were obtained using inductively coupled plasma mass spectrometry (ICP-MS). Toxicity was determined by clinical chemistry and hematology from blood samples in three different periods; light microscopy (LM) and scanning electron microscopy (SEM) were applied to evaluate histopathology in tissues. Silver concentrations were higher in small intestine, followed by kidney, liver, and brain. Clinical chemistry and hematology showed altered values in blood urea nitrogen, total proteins, and mean corpuscular hemoglobin, concentration values had statistical difference in both groups (14 and 36 nm) (p < 0.05). LM, SEM, ICP-MS, clinical chemistry, and hematology tests suggest that the administration way, concentration, shape, size, presentation, administration time of SNP used in this study, do not change significantly these values.

The Promotion of Peace Education through Guides in Peace Museums. A Case Study of the Kyoto Museum for World Peace, Ritsumeikan University

Science.gov (United States)

Tanigawa, Yoshiko

2015-01-01

This paper focuses on how peace education at a peace museum is promoted by a volunteer guide service for visitors. Peace museums are places where many materials related to war and peace history are on display. To support the learning experience of museum visitors, many peace museums in Japan provide a volunteer guide service. The Kyoto Museum for…

Effect of an avocado oil-enhanced diet (Persea americana) on sucrose-induced insulin resistance in Wistar rats.

Science.gov (United States)

Del Toro-Equihua, Mario; Velasco-Rodríguez, Raymundo; López-Ascencio, Raúl; Vásquez, Clemente

2016-04-01

A number of studies have been conducted to evaluate the effects of vegetable oils with varying percentages of monounsaturated and polyunsaturated fatty acids on insulin resistance. However, there is no report on the effect of avocado oil on this pathologic condition. The aim of this work was to evaluate the effect of avocado oil on sucrose-induced insulin resistance in Wistar rats. An experimental study was carried out on Wistar rats that were randomly assigned into six groups. Each group received a different diet over an 8-week period (n = 11 in each group): the control group was given a standard diet, and the other five groups were given the standard feed plus sucrose with the addition of avocado oil at 0%, 5%, 10%, 20%, and 30%, respectively. Variables were compared using Student t test and analysis of variance. Statistically significant difference was considered when p avocado oil showed lower insulin resistance (p = 0.022 and p = 0.024, respectively). Similar insulin resistance responses were observed in the control and 30% avocado oil addition groups (p = 0.85). Addition of 5-30% avocado oil lowered high sucrose diet-induced body weight gain in Wistar rats. It was thus concluded that glucose tolerance and insulin resistance induced by high sucrose diet in Wistar rats can be reduced by the dietary addition of 5-20% avocado oil. Copyright © 2016. Published by Elsevier B.V.

Government spending on Canada's oil and gas industry : undermining Canada's Kyoto commitment

International Nuclear Information System (INIS)

Taylor, A.; Bramley, M.; Winfield, M.

2005-01-01

This study investigates government spending in the Canadian oil and gas industry within the context of greenhouse gas emission trends and Kyoto commitments. Various forms of provincial and federal government support provided between 1996 and 2002 through grants, tax expenditures, and government program expenditures for conventional oil and gas and oil sands sectors are presented. The paper contextualizes government support for oil and gas production, discusses what constitutes a subsidy, presents the methodology and approach used to establish expenditure estimates, presents the study findings and discusses expenditure estimates and puts the results into the context of other public policy work. The conclusion recommends policy changes and describes important areas for future research related to public expenditure on oil and gas production. The study concludes that while it is understood that reform or removal of environmentally harmful subsidies will not solve environmental problems alone, such actions are important in order to achieve environmental improvements and objectives. 163 refs., 24 tabs, 5 figs

Effects of uterine cervix constriction on Wistar rats Efeitos da constrição do cérvix uterino em ratos Wistar

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Cassio Eduardo Raposo-Amaral

2010-12-01

Full Text Available PURPOSE: To verify if uterine cerclage can induce craniosynostosis or any cranial deformity in new born Wistar rats. METHODS: One pregnant female Wistar rat underwent laparotomy on day 18 of gestation and the uterus cervix was closed with a 3-0 nylon suture to avoid delivery, that occurs normally on the 21 day. The suture was released after 48 hours beyond the normal gestation period. The female rat delivered 11 pups. Six surviving rats from the delivery (group A - constrained group. Two rats were born from another mother and in the same age were used as control group (group B - 2 nonconstrained controls were allowed to grow. They were sacrificed 1.2 years after their birth all the eight animals. Linear measurement, routine histology and computed tomography of the skull were performed at the time of their death to evaluate the cranial asymmetries by mesurements of the anatomical landmarks of the craniofacial skeleton of the rats on the two groups and compared then. RESULTS: We did not observe statistically significant differences in any of the compared measurements (p>0.05 obtained through the morphologic and radiologic methods. Histologic examinations did not reveal any sign of premature fusion or suture imbrications. Critical decrease in longitudinal body size was noticed as the limbs too in all the animals of group A. CONCLUSION: Constriction of uterine cervix leads to fetus suffering, even death for a few animals, associated to small body size, but not to craniosynostosis.OBJETIVO: Verificar se a cerclagem intra-uterina pode induzir, ao nascimento de ratos Wistar, craniossinostose ou qualquer outra deformidade craniana. MÉTODOS: Uma rata Wistar prenhe foi submetida à laparotomia no 18º dia de gestação e o cérvix uterino foi suturado com 3-0 nylon, impedindo o parto normal que normalmente ocorre no 21º dia de gestação. A sutura foi liberada 48 horas após o período gestacional normal. A rata gestante deu à luz 11 animais. Seis

National inventory report for France under the UN Framework Convention on Climate Change (UNFCCC) and the Kyoto Protocol - CCNUCC, March 2011

International Nuclear Information System (INIS)

Chang, Jean-Pierre; Fontelle, Jean-Pierre; Nicco, Laetitia; Andre, Jean-Marc; Deflorenne, Emmanuel; Druart, Ariane; Gueguen, Celine; Jabot, Julien; Jacquier, Guillaume; Joya, Romain; Martinet, Yann; Mathias, Etienne; Prouteau, Emilie; Serveau, Laetitia; Vincent, Julien; Allemand, Nadine; Bastide, Aurelie; Gavel, Antoine; Kessouar, Sabrina; Tuddenham, Mark; Millard, Frederique; MArtineaud, Helene; MILLION, Aurelien; Nikov, Dimitar; Guittet, Olivier

2011-03-01

This national inventory report supplies emission data for France within the period 1990-2009, concerning all the substances that contribute to enhancing the greenhouse effect, required under: the United Nations Framework Convention on Climate Change (UNFCCC), the second year of commitment to the Kyoto Protocol (2008-2012). The substances covered are the direct greenhouse gases comprising the Kyoto Protocol 'basket of six': carbon dioxide (CO 2 ), methane (CH 4 ), nitrous oxide (N 2 O), the two species of halogenous substances, hydro-fluorocarbons (HFCs) and per-fluorocarbons (PFCs), and sulphur hexafluoride (SF 6 ). Emissions of sulphur dioxide (SO 2 ), nitrogen oxides (NO x ), non methane volatile organic compounds (NMVOCs), and carbon monoxide (CO), have also to be reported by the Parties under the Convention. For the period 1990-2008 as a whole, estimates provided in the previous inventories have been reviewed and corrected to take into account updated statistics, improved knowledge, possible changes in methodology and specifications contained in the guidelines (FCCC/SBSTA/2006/9), as defined by the UNFCCC. Several changes have been added to take into account the remarks of the reviews of UNFCCC. Although significant continuous progress has been achieved in terms of the sources covered and the quality of estimates, considerable uncertainties remain concerning emissions. These should be borne in mind when using the data in this report. A table indicating uncertainties based on current knowledge has been included in the report. Future reviews of these data are always possible, if not probable, to take into account both changes in methodology and work underway at international level with a view to improving knowledge and rules on compiling and presenting emissions. To answer specifically to the Kyoto Protocol's requirements, this report also includes the requirements supplementary information required under Article 7, paragraph 1, and Article 3, paragraph 14 of the

The Kyoto protocol: assessment and perspectives. Towards a new regime up to the climate stake

International Nuclear Information System (INIS)

Gautier, Celia

2012-01-01

This report proposes an analysis within the context of transition of the climate regime from the 'before-2012' regime to the 'post-2020' regime. It first gives an overview of international stakes and context (lack of ambition for climate policy, perspective of an international agreement from 2020). Then, the authors recall the history and achievements of the Kyoto protocol which is the basis of the present climate policy regime. They propose an assessment of actions performed by countries during the first period of the protocol, and focus on the present climate regime elements which are to be safeguarded. They analyse the weaknesses of the present regime, and propose possible improvements for the future post-2020 climate regime

Effects of bentonite on plasma urea and creatinine of wistar albino rats.

African Journals Online (AJOL)

The in vivo effect of Nigerian calcium bentonite clay on wistar albino rat plasma urea and creatinine levels were investigated. The rats were fed for a period of four weeks with varying concentrations of the bentonite clay, and the urea and creatinine levels determined using spectrophotometric methods. Test results showed ...

Future plans on the Kyoto University Research Reactor (KUR)

International Nuclear Information System (INIS)

Shibata, Seiichi

2000-01-01

The Research Reactor Institute (RRI), Kyoto University, for aiming at performing the 'Experiments using a reactor and its related research', was established in Showa 38 (1963) as a cooperative research institute for universities and so on in allover Japan. Operation using KUR of one of main facilities in RRI was started by 1 MW of its rated output in 1964, and converted to 5 MW in 1968, after which through development , addition and modification of various research apparatus it has been proposed to the cooperative application researches with universities and so on in allover Japan, hitherto. Among these periods, its research organization is improved to six departments containing twenty divisions and two attached research facilities to progress some investigations on future plans at RRI for response to new researching trends. Here were described on present state of research on use of low concentrated uranium fuels at research reactor, and future plans on neutron factory and hybrid reactor. The former aims at establishment of a new research facility capable of alternating to KUR for future academic research on research reactor containing high quality and high degree application of neutron field and safety management and feature upgrading of nuclear energy. And, the latter aims at development on an accelerator drive uncritical reactor combined an accelerator neutron source and an uncritical reactor. (G.K.)

Accelerator mass analysis at tandem accelerator in Kyoto University

Energy Technology Data Exchange (ETDEWEB)

Nakamura, Masanobu; Tazawa, Yuji; Matsumoto, Hiroshi; Hirose, Masanori [Kyoto Univ. (Japan). Faculty of Science; Ogino, Koya; Kohno, Masuchika; Funaba, Hiroyuki

1996-12-01

Tandem accelerator in Science Faculty, Kyoto University was renewed from 5 MV in the highest terminal voltage of Van de Graaff to 8 MV of Peletron in 1992. And, AMS effective for cosmic ray, dating, environment measurement and so forth is determined to a column of collaborative studies by universities and institutes in Japan. On this renewal, because of using high energy beam transportation of the present tandem accelerator, super high sensitivity measurement of long half-life radioactive isotopes of heavy elements such as {sup 36}Cl, {sup 41}Ca, {sup 129}I and so forth is aimed, although having some limitations due to small magnet. The accelerator is active in characteristics of the middle size tandem accelerator, and developing {sup 14}C measurement for its standard technology, as aiming at {sup 36}Cl measurement, at first. As a result, in this tandem accelerator stable and high beam transmittance could be obtained by adding a slit at negative ion source to make emittance of incident beam smaller. {sup 14}C/{sup 12}C ratio of Modan`s sample obtained by graphitizing NBS oxalic acid and Ded`s sample consisting of mineral graphite produced in Sri Lanka are measured to confirm better reproductivity of this system. Future development of successive incident method is planned to test actual carbon samples. (G.K.)

Alleviation of metabolic abnormalities induced by excessive fructose administration in Wistar rats by Spirulina maxima.

Science.gov (United States)

Jarouliya, Urmila; Zacharia, J Anish; Kumar, Pravin; Bisen, P S; Prasad, G B K S

2012-03-01

Diabetes mellitus is a metabolic disorder characterized by hyperglycaemia. Several natural products have been isolated and identified to restore the complications of diabetes. Spirulina maxima is naturally occurring fresh water cyanobacterium, enriched with proteins and essential nutrients. The aim of the study was to determine whether S. maxima could serve as a therapeutic agent to correct metabolic abnormalities induced by excessive fructose administration in Wistar rats. Oral administration of 10 per cent fructose solution to Wistar rats (n = 5 in each group) for 30 days resulted in hyperglycaemia and hyperlipidaemia. Aqueous suspension of S. maxima (5 or 10%) was also administered orally once daily for 30 days. The therapeutic potential of the preparation with reference to metformin (500 mg/kg) was assessed by monitoring various biochemical parameters at 10 day intervals during the course of therapy and at the end of 30 days S. maxima administration. Significant (Pmaxima aquous extract. Co-administration of S. maxima extract (5 or 10% aqueous) with 10 per cent fructose solution offered a significant protection against fructose induced metabolic abnormalities in Wistar rats. The present findings showed that S. maxima exhibited anti-hyperglycaemic, anti-hyperlipidaemic and hepatoprotective activity in rats fed with fructose. Further studies are needed to understand the mechanisms.

Efeito das drogas anti-retrovirais sobre as taxas de fertilidade de ratas Wistar Effects of antiretroviral drugs on fertility of Wistar rats

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Ernesto Antonio Figueiró Filho

2002-12-01

írus da imunodeficiência humana.PURPOSE: to evaluate experimentally the effects of antiretroviral drugs used alone and in association upon the fertility of pregnant Wistar rats and the perinatal effects on the offspring. METHODS: adult female pregnant Wistar rats weighing 200-230 g were used. The antiretroviral drugs zidovudine (AZT, lamivudine (3TC and nelfinavir (NFV were used alone and in association at daily doses of ten times the dose normally used in pregnant women, proportionally to the animal's body weight. Seven groups were studied, including the control one. The experiment started on day 0 and the pregnant animals were sacrificed on day 21. The alive and dead fetuses, the total implantation sites and the total numbers of corporea lutea were used to calculate the fertility values. The statistical analysis was performed by Student's t test and by the Mann-Whitney test. RESULTS: there were no significant statistical differences regarding preimplantation loss and implantation efficiency values of the rats treated with isolated and associated antiretroviral drugs. There was a significant increase in the postimplantation loss values (control group: 7.6%; drug groups variation: 20.2-26.7%, a decrease in the fetal viability values (control group: 92.4%, drug groups variation: 73.3-79.8%, and a decreasing number of fetuses per animal (control group: 14.7; drug groups variation: 11.1-12.7. There was a significant weight reduction of the female rats and of the offspring of animals treated with 3TC, AZT + 3TC and AZT + 3TC + NFV. CONCLUSION: with the administration of high antiretroviral doses, important fertility effects could be observed, which showed that less histotoxic antiretroviral drugs must be studied in order to warrant the safety of using these medicines in pregnant HIV-1 - infected women.

Assessment of Environmental and Economic Consequences of Global Warming with Emphasis on the achievements of Kyoto Protocol Implementation in Iran

International Nuclear Information System (INIS)

Mohammadi, H.; Abbasi, F.; Kar Bakhshe Raveri, S.

2017-01-01

One of the most important issues which has recently drawn attention is the preservation of the earth's ecosystems due to the events and environmental crises caused by industrial activities. The formation of more than a dozen conventions and protocols in different areas of environment also shows the importance of this issue. Given the implementation of the Convention and the Protocol, particularly the economic, social and environmental effects on all countries, especially developing countries with weak and vulnerable economy, in this article we Introduce environmental indices for Sustainable Development. In the case of carbon dioxide emissions, to examine emissions spectrum in the member states of Kyoto Protocol concurrent with the implementation of the first period, then climatic approaches were analyzed after the implementation of the first round. This research employs explanatory- analysis method. Examining indices shows that industrialized countries meet environmental requirements of the Kyoto Protocol and with regard to their own economic policy try to fulfill their obligations to reduce their greenhouse gas emissions but we face the global trend of rising emissions. This trend can be observed in non-Annex countries, including the Islamic Republic of Iran that there is no obligation in the first round to reduce greenhouse gas emissions.

Report of researches by common utilization of facilities in Kyoto University Research Reactor Institute, first half of fiscal year 1981

International Nuclear Information System (INIS)

1983-01-01

The technical report of the Kyoto University Research Reactor Institute is published any time to immediately report on the results of the functional tests of various experimental facilities, the test results for the products made for trial, radiation control, the situation of waste treatment, the data required for research and experiment such as the reports of study meetings, the conspicuous results obtained amid researches, new processes, and the discussion on other papers and reports. In this report, the title, the names of reporters and the summary of 57 researches carried out by the common utilization of the facilities in the Kyoto University Research Reactor Institute are collected. The themes of the researches are such as neutron radiography using a research reactor, measurement of Zr/Hf ratio in zirconium, interstitial germanium atoms in thermal neutron irradiation study, measurement of induced radioactivity due to neutrons in Nagasaki and Hiroshima atomic bombings, properties of semiconductor electrons in radiation study, induction of mutation in crops by neutron irradiation and utilization for breeding, thermal fluorescence mechanism of alkali halide and MgO single crystals, atomic configuration in PZT rhombohedron phase, modulated structure of Cu-Co alloys, excitation of nuclei by positron annihilation and others. (Kako, I.)

Report of researches by common utilization of facilities in Kyoto University Research Reactor Institute, latter half of fiscal year 1981

International Nuclear Information System (INIS)

1983-01-01

The technical report of the Kyoto University Research Reactor Institute is published any time to immediately report on the results of the functional tests of various experimental facilities, the test results for the products made for trial, radiation control, the situation of waste treatment, the data required for research and experiment such as the reports of study meetings, the conspicuous results obtained amid researches, new processes, and the discussion on other papers and reports. In this report, the title, the names of reporters and the summary of 61 researches carried out by the common utilization of the facilities in the Kyoto University Research Reactor Institute are collected. The themes of the researches are such as radioactivation analysis of trace elements in rocks and minerals, anodic oxidation films of GaAs and structure, measurement of yield of uranium isotopes produced by reactor neutron irradiation of thorium, geochemical study of trace elements in hydrosphere by radio-activation analysis, various diseases and variation of elements in rat furs, Moessbauer spectroscopic study of gold compounds with singular coupling by Au-197, measurement of grass-eating quantity and rate of digestion of cows using Au and Eu, sickness biochemical study of trace elements in hair samples of patients and others. (Kako, I.)

A low-carbohydrate/high-fat diet reduces blood pressure in spontaneously hypertensive rats without deleterious changes in insulin resistance

OpenAIRE

Bosse, John D.; Lin, Han Yi; Sloan, Crystal; Zhang, Quan-Jiang; Abel, E. Dale; Pereira, Troy J.; Dolinsky, Vernon W.; Symons, J. David; Jalili, Thunder

2013-01-01

Previous studies reported that diets high in simple carbohydrates could increase blood pressure in rodents. We hypothesized that the converse, a low-carbohydrate/high-fat diet, might reduce blood pressure. Six-week-old spontaneously hypertensive rats (SHR; n = 54) and Wistar-Kyoto rats (WKY; n = 53, normotensive control) were fed either a control diet (C; 10% fat, 70% carbohydrate, 20% protein) or a low-carbohydrate/high-fat diet (HF; 20% carbohydrate, 60% fat, 20% protein). After 10 wk, SHR-...

The Establishment of Metabolic Syndrome Model by Induction of Fructose Drinking Water in Male Wistar Rats

Directory of Open Access Journals (Sweden)

Norshalizah Mamikutty

2014-01-01

Full Text Available Background. Metabolic syndrome can be caused by modification of diet by means of consumption of high carbohydrate and high fat diet such as fructose. Aims. To develop a metabolic syndrome rat model by induction of fructose drinking water (FDW in male Wistar rats. Methods. Eighteen male Wistar rats were fed with FDW 20% and FDW 25% for a duration of eight weeks. The physiological changes with regard to food and fluid intake, as well as calorie intake, were measured. The metabolic changes such as obesity, dyslipidaemia, hypertension, and hyperglycaemia were determined. Data was presented in mean ± SEM subjected to one-way ANOVA. Results. Male Wistar rats fed with FDW 20% for eight weeks developed significant higher obesity parameters compared to those fed with FDW 25%. There was hypertrophy of adipocytes in F20 and F25. There were also systolic hypertension, hypertriglyceridemia, and hyperglycemia in both groups. Conclusion. We conclude that the metabolic syndrome rat model is best established with the induction of FDW 20% for eight weeks. This was evident in the form of higher obesity parameter which caused the development of the metabolic syndrome.

Can prenatal low-dose irradiation affect behavior of adult rats?

International Nuclear Information System (INIS)

Smajda, B.; Tomasova, L.; Kokocova, N.

2011-01-01

The aim of our study was to determine whether exposure of very low dose gamma-rays during the critical phase of brain development affects some selected behavioral parameters in adult rats. Pregnant female Wistar rats were irradiated with 1 Gy gamma-rays from a cobalt source at 17 th day of pregnancy. The progeniture of irradiated as well as non-irradiated females have undergone behavioral tests at the age of 3 months. Irradiated animals exhibited lower locomotor and exploratory activity in the open field test. (authors)

Mexamine used to decrease radiation damage to Wistar rat embryogenesis

International Nuclear Information System (INIS)

Palyga, G.F.; Zakoshchikov, K.F.

1987-01-01

In experiments with 330 Wistar rats experiencing their pregnancy and 1430 neonatal rats of the first generation a study was made on the toxicity and radioprotective efficiency of a single subcutaneous injection of 10 mg/kg mexamine on days 3, 11 and 19 pregnancy. The agent caused various abnormalities in pregnancy, delivery and postnatal development of the offspring of nonirradiated animals, and it was almost ineffective when used for the prevention of radiation damages during the anrnatal ontogenesis

Report of research by common utilization in Research Reactor Institute, Kyoto University, in latter half of fiscal 1980

International Nuclear Information System (INIS)

1982-01-01

In the technical report, the data required for research and experiment, such as the result of functional test of various experimental facilities, the test results of the products manufactured for trial, the state of radiation control and waste treatment, and the reports of study meetings, or the remarkable results and new methods obtained in research and the discussion on other papers and reports in the Research Reactor Institute, Kyoto University, are summarized as prompt report. The subject, reporters and synopsis of 69 papers are reported in this publication. (Kako, I.)

Report of research by common utilization in Research Reactor Institute, Kyoto University, in first half of fiscal 1980

International Nuclear Information System (INIS)

1982-01-01

In the technical report, the data required for research and experiment, such as the result of functional test of various experimental facilities, the test results of the products manufactured for trial, the state of radiation control and waste treatment, and the reports of study meetings, or the remarkable results and new methods obtained in research, and the discussion on other papers and reports in the Research Reactor Institute, Kyoto University, are summarized as prompt report. The subject, reporters and synopsis of 54 papers are reported in this publication. (Kako, I.)

Assessing and training standing balance in older adults: a novel approach using the 'Nintendo Wii' Balance Board.

Science.gov (United States)

Young, William; Ferguson, Stuart; Brault, Sébastien; Craig, Cathy

2011-02-01

Older adults, deemed to be at a high risk of falling, are often unable to participate in dynamic exercises due to physical constraints and/or a fear of falling. Using the Nintendo 'Wii Balance Board' (WBB) (Nintendo, Kyoto, Japan), we have developed an interface that allows a user to accurately calculate a participant's centre of pressure (COP) and incorporate it into a virtual environment to create bespoke diagnostic or training programmes that exploit real-time visual feedback of current COP position. This platform allows researchers to design, control and validate tasks that both train and test balance function. This technology provides a safe, adaptable and low-cost balance training/testing solution for older adults, particularly those at high-risk of falling. Copyright © 2010 Elsevier B.V. All rights reserved.

Ion and electron Van de Graaff accelerators of Kyoto University

International Nuclear Information System (INIS)

Fukuzawa, F.; Imanishi, N.; Tomita, M.; Norisawa, K.; Yoshida, K.; Ohdaira, T.

1990-01-01

Two Van de Graaff accelerators are available at the Uji campus of Kyoto University. One is a 4MV machine, which is used for heavy ion acceleration, while the other is a 2MV machine for electron acceleration. These machines have been modified in various parts and currently used very actively in many fields of investigation. Important modifications of the 4MV machine are: use of a newly developed accelerating tube, addition of a charge-changer before the analyzing magnet, renewal of the charging belt, and development of a microbeam system for PIXE and RBS analysis. An attempt is now being made to accelerate micro-particles using the 2MV machine. The new accelerating tube has bucket type electrodes with large accelerating apertures. By charge-changing the accelerated 1+ ions to higher charge states, 2+, 3+, ..., at the entrance of the analyzing magnet, Ar ions with energies of up to 2.73, 6.21, .... MeV can be deflected to the duct. Scanning microbeam PIXE and RBS are powerful tools for analysis of spatial elemental distribution. Calculations suggest that a beam size of about 3 μm can be attained by using an object aperture of 10μm in diameter and controlling the beam divergence within 10μ rad in both directions. (N.K.)

Resolving issues on terrestrial biospheric sinks in the Kyoto Protocol

Energy Technology Data Exchange (ETDEWEB)

Nabuurs, G.J.; Verkaik, E.; Mohren, G.M.J. [DLO Institute for Forestry and Nature Research IBN-DLO, Wageningen (Netherlands); Dolman, A.J.; Kabat, P. [DLO Winand Staring Centre SC-DLO, Wageningen (Netherlands); Whitmore, A.P.; Oenema, O. [DLO Institute for Agrobiology AB-DLO, Wageningen (Netherlands); Daamen, W.P. [Consulatancy Daamen, Schoonderwoerd and De Klein, Kesteren (Netherlands)

1999-08-01

In the Kyoto Protocol, all Annex I countries have agreed to reduce their carbon dioxide emissions with a certain percentage in 2008-2012 compared to 1990. To achieve that target, some direct human induced activities initiated in the Land-use Change and Forestry sector since 1990, may be used. However, the wording in the Protocol has caused confusion on what is exactly meant in the Protocol, which activities may be included, whether soils should be included and whether any additional measures may be included in the future. Also, the way of monitoring, verification and reporting is unclear. In this NRP project the implications of a choice for a certain definition, additional compartments of the C cycle, and feasibility of monitoring are assessed for a limited number of countries. This is done by applying those definitions and additional measures to the countries` C budget on the latest data. The forest related matters are handled by the Institute for Forestry and Nature Research (IBN-DLO), the soil related matters are handled by the Research Institute for Agrobiology and Soil fertility (AB-DLO), the monitoring and verification matters are handled by the Winand Staring Centre for Integrated Land, Soil and Water Research (SC-DLO). 120 refs.

Effect of Lactobacillus casei on the Pharmacokinetics of Amiodarone in Male Wistar Rats

Czech Academy of Sciences Publication Activity Database

Matušková, Z.; Anzenbacher, P.; Večeřa, R.; Siller, M.; Tlaskalová-Hogenová, Helena; Strojil, J.; Anzenbacherová, E.

2017-01-01

Roč. 42, č. 1 (2017), s. 29-36 ISSN 0378-7966 R&D Projects: GA ČR(CZ) GAP303/12/0535 Institutional support: RVO:61388971 Keywords : Lactobacillus casei * Amiodarone * Wistar Rats Subject RIV: EE - Microbiology, Virology OBOR OECD: Microbiology Impact factor: 1.400, year: 2016

Induction of hepatic aryl hydrocarbon hydroxylase and epoxide hydrase in Wistar rats pretreated with oral methadone hydrochloride.

Science.gov (United States)

Bellward, G D; Gontovnick, L S; Otten, M

1977-01-01

Methadone-HCl added to the drinking water of adult female Wistar rats for 4 weeks produced an increase in the aryl hydrocarbon hydroxylase activity of the hepatic microsomal fraction to 222% of control levels. No change was seen in epoxide hydrase activity. In contrast, when male rats were treated similarly, there was an increase in epoxide hydrase activity to 212% of controls with no change in aryl hydrocarbon hydroxylase activity. No such changes were observed when the subcutaneous route of administration or chronic, low-dose, intraperitoneal injections were used. There were no differences in hepatic cytochrome P-450 or protein concentrations in treated animals as compared to their respective control groups. Control studies were carried out with quinine sulfate in the drinking water to decrease water intake to the level of the methadone-treated group. No elevation in either enzyme activity occurred in this control group. Similarly, paired-feeding studies showed the elevation of enzyme activity to be due to the methadone, not food deprivation. The effects of concurrent therapy of methadone with phenobarbital sodium or 3-methylcholanthrene were compared.

Ameliorative Effects of Acacia Honey against Sodium Arsenite-Induced Oxidative Stress in Some Viscera of Male Wistar Albino Rats

OpenAIRE

Muhammad Aliyu; Sani Ibrahim; Hajiya M. Inuwa; Abdullahi B. Sallau; Olagunju Abbas; Idowu A. Aimola; Nathan Habila; Ndidi S. Uche

2013-01-01

Cancer is a leading cause of death worldwide and its development is frequently associated with oxidative stress-induced by carcinogens such as arsenicals. Most foods are basically health-promoting or disease-preventing and a typical example of such type is honey. This study was undertaken to investigate the ameliorative effects of Acacia honey on sodium arsenite-induced oxidative stress in the heart, lung and kidney tissues of male Wistar rats. Male Wistar albino rats divided into four groups...

Evaluation of protein undernourishment on the condylar process of the Wistar rat mandible correlation with insulin receptor expression

Directory of Open Access Journals (Sweden)

Marcelo Arthur CAVALLI

2015-04-01

Full Text Available The mandible condylar process cartilage (CP of Wistar rats is a secondary cartilage and acts as a mandibular growth site. This phenomenon depends on adequate proteins intake and hormone actions, including insulin. Objectives The present study evaluated the morphological aspects and the expression of the insulin receptor (IR in the cartilage of the condylar process (CP of rats subjected to protein undernourishment. Material and Methods The nourished group received a 20% casein diet, while the undernourished group (U received a 5% casein diet. The re-nourished groups, R and RR, were used to assess the effects of re-nutrition during puberty and adulthood, respectively. CPs were processed and stained with picro-sirius red, safranin-O and azocarmine. Scanning electron microscopy and immunohistochemistry were also performed. Results The area of the CP cartilage and the number of cells in the chondroblastic layer decreased in the U group, as did the thickness of the CP layer in the joint and hypertrophic layer. Renourishment during the pubertal stage, but not during the adult phase, restored these parameters. The cell number was restored when re-nutrition occurred in the pubertal stage, but not in the adult phase. The extracellular matrix also decreased in the U group, but was restored by re-nutrition during the pubertal stage and further increased in the adult phase. IR expression was observed in all CPs, being higher in the chondroblastic and hypertrophic cartilage layers. The lowest expression was found in the U and RR groups. Conclusions Protein malnutrition altered the cellularity, the area, and the fibrous cartilage complex, as well as the expression of the IRs.

Sweet taste of saccharin induces weight gain without increasing caloric intake, not related to insulin-resistance in Wistar rats.

Science.gov (United States)

Foletto, Kelly Carraro; Melo Batista, Bruna Aparecida; Neves, Alice Magagnin; de Matos Feijó, Fernanda; Ballard, Cíntia Reis; Marques Ribeiro, Maria Flávia; Bertoluci, Marcello Casaccia

2016-01-01

In a previous study, we showed that saccharin can induce weight gain when compared with sucrose in Wistar rats despite similar total caloric intake. We now question whether it could be due to the sweet taste of saccharin per se. We also aimed to address if this weight gain is associated with insulin-resistance and to increases in gut peptides such as leptin and PYY in the fasting state. In a 14 week experiment, 16 male Wistar rats received either saccharin-sweetened yogurt or non-sweetened yogurt daily in addition to chow and water ad lib. We measured daily food intake and weight gain weekly. At the end of the experiment, we evaluated fasting leptin, glucose, insulin, PYY and determined insulin resistance through HOMA-IR. Cumulative weight gain and food intake were evaluated through linear mixed models. Results showed that saccharin induced greater weight gain when compared with non-sweetened control (p = 0.027) despite a similar total caloric intake. There were no differences in HOMA-IR, fasting leptin or PYY levels between groups. We conclude that saccharin sweet taste can induce mild weight gain in Wistar rats without increasing total caloric intake. This weight gain was not related with insulin-resistance nor changes in fasting leptin or PYY in Wistar rats. Copyright © 2015 Elsevier Ltd. All rights reserved.

A gestational diet high in fat-soluble vitamins alters expression of genes in brain pathways and reduces sucrose preference, but not food intake, in Wistar male rat offspring.

Science.gov (United States)

Sanchez-Hernandez, Diana; Poon, Abraham N; Kubant, Ruslan; Kim, Hwanki; Huot, Pedro S P; Cho, Clara E; Pannia, Emanuela; Pausova, Zdenka; Anderson, G Harvey

2015-04-01

High intakes of multivitamins (HV) during pregnancy by Wistar rats increase food intake, body weight, and characteristics of the metabolic syndrome in male offspring. In this study, high-fat soluble vitamins were fed in combination during gestation to test the hypothesis that they partially account for the effects of the HV diet. Pregnant Wistar rats (14-16/group) were fed a recommended multivitamin diet (1-fold all vitamins) or high-fat soluble vitamin diet (HFS; 10-fold vitamins A, D, E, and K) during pregnancy. Offspring body weight, food intake, and preference as well as expression of selected genes in the hypothalamus and hippocampus were evaluated at birth, weaning, and 14 weeks postweaning. Body weight and food intake were not affected but sucrose preference decreased by 4% in those born to dams fed the HFS gestational diet. Gene expressions of the hypothalamic anorexogenic pro-opiomelanocortin (Pomc) and orexogenic neuropeptide Y (Npy) (∼30% p = 0.008, ∼40% p = 0.007) were increased in weaning and adult rats, respectively. Hippocampal dopaminergic genes (35%-50% p vitamins A, D, E, and K does not show the effects of the HV diet on body weight or food intake but may affect the development of higher hedonic regulatory pathways associated with food preference.

Radionecrosis attenuation in wistar rats with cutaneous application of quercetin

International Nuclear Information System (INIS)

Alves, Nelson Mendes

2016-01-01

The increased incidence of cancer has been significant in recent decades in the world population, as confirmed by national and international institutions in the health area. The emergence of cancer is influenced, predominantly by genetic and environmental factors, being manifested more in the adult population. The main modalities for cancer treatment (radiotherapy, chemotherapy and surgery) may be used separately or in combination, depending on the type of cancer. Among the methods mentioned, radiation therapy is the one more broadly used for the treatment of patients, having an associated side effect called radiodermatitis, which has degrees of severity ranging from simple erythema to radionecrosis. The manifestation of radiodermatitis may occur during the treatment or after the radiotherapy sessions: both situations have great relevance in the patient's quality of life and social costs. One of the studied alternative therapies for attenuating the radionecrosis is the quercetin cutaneous application. One of the alternative therapies, studied to mitigate or eliminate the radionecrosis, is based on the topical application of quercetin. To evaluate the effectiveness of this mitigation, an animal model of radionecrosis was developed, to be used in Wistar rats. After in vitro studies, the quercetin concentrations and time of application were determined, reducing the number of animals, when in vivo experiments are carried out. With the topical application of 250 μ mol/L of quercetin, one hour prior to gamma irradiation, at a dose of 85 Gy, the side effects of radiation were minimized, avoiding the formation of radionecrosis. There was, also, a tendency to attenuate the wound area in the studied animals, compared to the irradiated animals without the quercetin application. (author)

Comprehensive modelling for approaching the Kyoto targets on a local scale

International Nuclear Information System (INIS)

Pietrapertosa, F.; Macchiato, M.; Salvia, M.

2003-01-01

This study aimed to evaluate the effectiveness of the MARKAL comprehensive model in the development of coherent medium-term strategies and sound climate protection policies at local level. The local case study (Val d'Agri, Basilicata region, Italy) discusses the possible role of local communities in the achievement of the national objectives derived by the Kyoto Protocol, investigating the traditional sectors responsible for air pollution and providing a full picture of the main energy and material flows. A scenario analysis was performed to analyse the response of the modelled system to the introduction of an exogenous constraint on carbon dioxide (CO 2 ) emissions. The main effects are presented with reference to fuel mix, technology choice, real market prices and reduced costs of competing options. The comparison of the solutions obtained for the different scenarios is useful to point out the effects of the CO 2 constraint on the total system cost and on the emission levels of other atmospheric pollutants. A further multiobjective optimisation was performed to analyse the effects of combined environmental constraints (CO 2 and particulate) on the overall system cost as well as in terms of marginal costs. (author)

Comprehensive modelling for approaching the Kyoto targets on a local scale

Energy Technology Data Exchange (ETDEWEB)

Pietrapertosa, F. [Istituto di Metodologie per l' Analisi Ambientale, Tito Scalo (Italy); Universita degli Studi della Basilicata, Potenza (Italy). Dipartimento di Ingegneria e Fisica dell' Ambiente; Cosmi, C.; Marmo, G. [Istituto di Metodologie per l' Analisi Ambientale, Tito Scalo (Italy); Istituto Nazionale di Fisica della Materia, Napoli (Italy); Macchiato, M. [Universita Federico II, Napoli (Italy). Dipartimento di Scienze Fisiche; Salvia, M. [Istituto di Metodologie per l' Analisi Ambientale, Tito Scalo (Italy)

2003-06-01

This study aimed to evaluate the effectiveness of the MARKAL comprehensive model in the development of coherent medium-term strategies and sound climate protection policies at local level. The local case study (Val d'Agri, Basilicata region, Italy) discusses the possible role of local communities in the achievement of the national objectives derived by the Kyoto Protocol, investigating the traditional sectors responsible for air pollution and providing a full picture of the main energy and material flows. A scenario analysis was performed to analyse the response of the modelled system to the introduction of an exogenous constraint on carbon dioxide (CO{sub 2}) emissions. The main effects are presented with reference to fuel mix, technology choice, real market prices and reduced costs of competing options. The comparison of the solutions obtained for the different scenarios is useful to point out the effects of the CO{sub 2} constraint on the total system cost and on the emission levels of other atmospheric pollutants. A further multiobjective optimisation was performed to analyse the effects of combined environmental constraints (CO{sub 2} and particulate) on the overall system cost as well as in terms of marginal costs. (author)

A post-Kyoto analysis of the Greek electric sector

International Nuclear Information System (INIS)

Dagoumas, A.S.; Kalaitzakis, E.; Papagiannis, G.K.; Dokopoulos, P.S.

2007-01-01

The obligations resulting from the Kyoto Protocol (KP) are implemented by many participants, e.g. Greece, by a combination of two methods: (a) application of regional measures which restrict CO 2 emissions and (b) procurement of green certificates e.g. in a Climate Exchange Market (CEX). Therefore, the cost for compliance with the KP depends on the extent each method is used and also on the traded values in the CEX. The energy policy and planning to be considered are long-term items and now extension of the KP to a post-KP is discussed which reaches year 2020. In Greece, the electricity sector is with a weighted CO 2 contribution of 73%, the dominantly emission sector. The paper analyzes the cost and other merits of different scenarios for the expansion of electrical power system in Greece. For different scenarios, the total cost of the electrical power system expansion is calculated as a function of the price of emission certificates. It has been shown that there is a price of 27.5 Euro /tCO 2 , above which specific mitigation measures may lead to cost optimum solutions. A sensitivity analysis is also presented concerning the variation of key parameters like the participation in the system expansion of new supercritical coal units, the price evolution of natural gas, the RES usage rate and the discount rates of the expansion investments. Results may be of interest for a decision on the cost optimum electrical power system expansion

Ascorbic acid treatment elevates follicle stimulating hormone and testosterone plasma levels and enhances sperm quality in albino Wistar rats

OpenAIRE

Okon, Uduak Akpan; Utuk, Ikponoabasi Ibanga

2016-01-01

Background: Infertility issues have been linked to the effect of oxidative reaction in the reproductive system. This study evaluated the effect of ascorbic acid, on fertility parameters of male albino Wistar rats was studied. Materials and Methods: Eighteen albino Wistar rats weighed between 178 g and 241 g were used, randomly assigned into three groups. Group 1 was the control group; oral gavaged 5 ml of distilled water; Groups 2 and 3 were administered medium dose (250 mg/kg) and high dose ...

Interim report on construction of data base for atomic energy science documents (concerning Kyoto University Reactor)

International Nuclear Information System (INIS)

Takeuchi, Takayuki

1984-01-01

The Kyoto University Research Reactor Institute was established in 1963 as a research institute for all universities in Japan utilizing the facilities in common. The construction of a document data base has been undertaken in commemoration of the 20th anniversary of the institute. The data base concerns the research works performed at the institute and also the publications and reports on the research made by the personnel belonging to the institute. Input data are gathered from concerned researchers. In this interim report, the structure and contents of this data base are shortly described. One of the features of this data base is that it handles data with both Japanese and English at the same time. (Aoki, K.)

What can we learn from the endogeneization of the technical progress in GEM - E3? The case of the Kyoto protocol; Que pouvons nous apprendre de l'endogeneisation du progres technique dans GEM - E3? le cas du protocole de Kyoto

Energy Technology Data Exchange (ETDEWEB)

Fougeyrollas, A.; Le Mouel, P.; Zagame, P

2007-07-01

This project aims to study how the evaluation of the policies of fight against the greenhouse effect gases emission studied at an european scale, in the framework of the Kyoto agreements, is modified when the applied model, of general equilibrium takes into account the behavior of endogenous growth described by the new theories. More specially, the authors calibrated a production module with endogenous growth properties in the model GEM-E3. The new developed module show the costs reduction of policies of greenhouse effect gases emission limitation for France and Europe. (A.L.B.)

Maternal separation decreases adult hippocampal cell proliferation and impairs cognitive performance but has little effect on stress sensitivity and anxiety in adult Wistar rats.

Science.gov (United States)

Hulshof, Henriëtte J; Novati, Arianna; Sgoifo, Andrea; Luiten, Paul G M; den Boer, Johan A; Meerlo, Peter

2011-01-20

Stressful events during childhood are thought to increase the risk for the development of adult psychopathology. A widely used animal model for early life stress is maternal separation (MS), which is thought to affect development and cause alterations in neuroendocrine stress reactivity and emotionality lasting into adulthood. However, results obtained with this paradigm are inconsistent. Here we investigated whether this variation may be related to the type of stressor or the tests used to assess adult stress sensitivity and behavioral performance. Rat pups were exposed to a 3h daily MS protocol during postnatal weeks 1-2. In adulthood, animals were subjected to a wide variety of stressors and tests to obtain a better view on the effects of MS on adult hypothalamic-pituitary-adrenal (HPA) axis regulation, anxiety-like behavior, social interaction and cognition. Also, the influence of MS on adult hippocampal neurogenesis was studied because it might underlie changes in neuroendocrine regulation and behavioral performance. The results show that, independent of the nature of the stressor, MS did not affect the neuroendocrine response. MS did not influence anxiety-like behavior, explorative behavior and social interaction, but did affect cognitive function in an object recognition task. The amount of new born cells in the hippocampal dentate gyrus was significantly decreased in MS animals; yet, cell differentiation and survival were not altered. In conclusion, while interfering with the mother-infant relationship early in life did affect some aspects of adult neuroplasticity and cognitive function, it did not lead to permanent changes in stress sensitivity and emotionality. Copyright © 2010 Elsevier B.V. All rights reserved.

Effects of high fat diet on incidence of spontaneous tumors in Wistar rats

DEFF Research Database (Denmark)

KRISTIANSEN, E.; Madsen, Charlotte Bernhard; Meyer, Otto A.

1993-01-01

In a 2.5-year carcinogenicity study, two groups, both including male and female Wistar rats, were fed two different diets with 4% and 16% fat. In addition to 4% soybean oil, the high-fat diet contained 12% mono- and diglycerides, of which 85% was stearic acid and 13% palmitic acid...

Características ultra-estruturais do nó sinoatrial de rato Wistar Superstructural features of the wistar strain male rats' sinoatrial node (SAN

Directory of Open Access Journals (Sweden)

Carlos Alberto Mandarim de Lacerda

2002-04-01

Full Text Available As características ultra-estruturais do nó sinoatrial (NSA de 5 ratos machos da variedade Wistar, com 3 meses de idade, foram estudadas por meio de microscopia eletrônica de transmissão (MET. Fragmento pequeno, contendo a região do NSA e área adjacente do átrio direito do coração, foi retirado e fixado em glutaraldeído 2,5% e processado de acordo com técnica convencional para MET. A morfologia do nó sinoatrial de ratos é semelhante a de outros mamíferos. O NSA é uma estrutura anatômica independente do miocárdio atrial, constituído por células típicas (miócitos nodais, células de transição e, principalmente, células nodais imersos em matriz extracelular, na qual predominam fibras colágenas, fibroblastos e nervosThe superstructural features of five Wistar strain male rats' sinoatrial node (SAN at 3-mo-old were studied through transmission electron microscopy (TEM. Small fragments with the regions containing the SAN were cut off, fixed in glutaraldehyde 2.5% and processed according to the conventional technique for TEM. The morphology of the sinoatrial node of the rats is similar as found in other mammals. The SAN is an independent anatomic structure of the atrial myocardial, constituted of typical cells (nodal myocytes, transition cells and nodal cells principally immersed in the extra cellular matrix where collagen fibers, fibroblasts and nerve predominate

EFFECTS OF RESVERATROL ON LIVER FUNCTION OF OBESE FEMALE WISTAR RATS

Directory of Open Access Journals (Sweden)

Nádia Araújo Miguel

2016-07-01

Full Text Available Resveratrol has antioxidant, anti-inflammatory, lipolytic, and antifibrotic properties, which may be useful in supplementation of obese patients and with liver problems. This study evaluated the effects of 6-week resveratrol supplementation on the lipid profile and liver function of female Wistar rats fed a high-fat diet to induce obesity. Sixty-four Wistar rats were divided into 4 groups (n = 16: the control group (C; the control obese group (CO; the resveratrol group (R; and the resveratrol obese group (RO. At the end of the experiment, the animals were anesthetized for blood collection and subsequent euthanasia for collection of liver biopsy. The parameters for body weight, liver weight, retroperitoneal fat weight, serum lipid and liver profiles and histopathological analysis were evaluated. The 6-week resveratrol administration did not induce weight loss nor did it reduce the lipid profile; however, it decreased the liver enzymes aspartate aminotransferase (AST and alkaline phosphatase (ALP and reduced the incidence of steatosis (75.0% in group RO compared with group CO (81.2%. Thus, we concluded that resveratrol supplementation for the short period of six weeks had a beneficial effect on liver function by reducing hepatic steatosis and the liver enzymes AST and ALP in obese female rats. Keywords: liver function; obesity; rats; resveratrol.

O epitélio respiratório em ratos Wistar

Directory of Open Access Journals (Sweden)

Nuno A.A. Castelo Branco

2003-09-01

Full Text Available RESUMO: A doença vibroacústica é uma patologia sistémica, caracterizada pela proliferação anormal das matrizes extra-celulares e causada pela exposição crónica a ruído de baixa frequência (RBF (≤500 Hz, incluindo os infra-sons. Neste contexto, nos estudos conduzidos em ratos Wistar expostos a RBF, na tentativa de reproduzir a patologia observada em trabalhadores expostos a esta noxa, observaram-se aspectos não descritos. Urge assim esclarecer os aspectos normais em populações de ratos Wistar não expostos. Dez ratos Wistar, tratados de acordo com a norma 86/609/ CE, foram mantidos em silêncio até à idade de 3,5 meses e então sacrificados tendo sido colhidos fragmentos de traqueia e brônquios para microscopia óptica e electrónica de varrimento (MEV e de transmissão (MET. As células em escova (CE que se observam frequentemente em MET são menos visíveis em MEV, devido aos cílios das células vizinhas. São frequentes as estruturas em roseta, constituídas por um anel de células secretoras centradas numa CE. Em MET observam-se corpos multivesiculares dentro das CE. Observam-se, tanto em MEV como em MET, numerosas vesículas emanando da membrana plasmática dos cílios e das microvilosidades das CE. Estes dados podem contribuir para a compreensão da função das CE.REV PORT PNEUMOL 2003; IX (5: 381-388 ABSTRACT: Morphofunctional changes of respiratory epithelia became the object of intense study in Wistar rats after previous research showed that occupationally-simulated exposure to low frequency noise (≤500 Hz, including infrasound induced irreversible lesions in these tissues. Aspects of normal respiratory epithelia in rats are lacking in the literature, and are the object of this report. Ten Wistar rats were kept in silence, fed standard rat food, and had unrestrained access to water (treated in accordance with 86/609/CE. The

Carcinogenicity study on butylated hydroxytoluene (BHT) in Wistar rats exposed in utero

DEFF Research Database (Denmark)

Olsen, P.; Meyer, Otto A.; Bille, N.

1986-01-01

Groups of 60, 40, 40 and 60 F0 Wistar rats of each sex were fed a semi-synthetic diet containing butylated hydroxytoluene (BHT) in concentrations to provide intakes of 0, 25, 100 or 500 mg/kg body weight/day, respectively. The F0 rats were mated and groups of 100, 80, 80 or 100 F1 rats of each sex...

Biomedical irradiation system for boron neutron capture therapy at the Kyoto University Reactor

International Nuclear Information System (INIS)

Kobayashi, T.; Kanda, K.; Ujeno, Y.; Ishida, M.R.

1990-01-01

Physics studies related to radiation source, spectroscopy, beam quality, dosimetry, and biomedical applications using the Kyoto University Reactor Heavy Water Facility are described. Also, described are a Nickel Mirror Neutron Guide Tube and a Super Mirror Neutron Guide Tube that are used both for the measurement of boron concentration in phantom and living tissue and for precise measurements of neutron flux in phantom in the presence of both light and heavy water. Discussed are: (1) spectrum measurements using the time of flight technique, (2) the elimination of gamma rays and fast neutrons from a thermal neutron irradiation field, (3) neutron collimation without producing secondary gamma rays, (4) precise neutron flux measurements, dose estimation, and the measurement of boron concentration in tumor and its periphery using guide tubes, (5) the dose estimation of boron-10 for the first melanoma patient, and (6) special-purpose biological irradiation equipment. Other related subjects are also described

Biomedical irradiation system for boron neutron capture therapy at the Kyoto University reactor

International Nuclear Information System (INIS)

Kobayashi, T.; Kanda, K.; Ujeno, Y.; Ishida, M.R.

1990-01-01

Physics studies related to radiation source, spectroscopy, beam quality, dosimetry, and biomedical applications using the Kyoto University Reactor Heavy Water Facility are described. Also, described are a Nickel Mirror Neutron Guide Tube and a Super Mirror Neutron Guide Tube that are used both for the measurement of boron concentration in phantom and living tissue and for precise measurements of neutron flux in phantom in the presence of both light and heavy water. Discussed are: (1) spectrum measurements using the time of flight technique, (2) the elimination of gamma rays and fast neutrons from a thermal neutron irradiation field, (3) neutron collimation without producing secondary gamma rays, (4) precise neutron flux measurements, dose estimation, and the measurement of boron concentration in tumor and its periphery using guide tubes, (5) the dose estimation of boron-10 for the first melanoma patient, and (6) special-purpose biological irradiation equipment. Other related subjects are also described

Long-Time Choledochal Clamping in Wistar Rats Causes Biliary Obstruction Progressing to Hepatic Fibrosis.

Science.gov (United States)

Jorge, G D L; Tártaro, R R; Escanhoela, C A F; Boin, I D F S F

2016-09-01

Biliary complications are important causes of morbidity and mortality in patients undergoing hepatic surgery. The aim of the study was to evaluate late liver alterations after a long period of choledochal clamping in Wistar rats. Ten male Wistar rats, weighing 304 grams, anesthetized with sodium thiopental (25 mg/kg) and xylazine (10 mg/kg) intravenously, were distributed into 2 groups: the choledochal clamping group (CCG) and the operation sham group (OSG), with 5 animals each submitted to an abdominal incision. In the CCG, the choledochal was isolated, dissected, and clamped with a microvascular clamp for 40 minutes. After this occlusion time, the clamp was removed and the incision was closed. In the OSG the animals, under normal conditions, were submitted only to anesthesia and laparotomy for choledochal manipulation. In all animals, after the 31st day, a hepatic biopsy was carried out for histology and blood biochemical tests: total bilirubin, alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, and gamma-glutamyl transferase. The animals were euthanized under anesthesia. This research was approved by the Ethics Committee on Animal Use (CEUA, Unicamp, No. 2511-1). In the CCG, 100% of the animals showed bile duct dilatation, ductular proliferation, and portal inflammatory infiltrate; 60% showed regenerative nodule formation; and 80% had porta-porta septa and foci of necrosis, all of which were not found in the OSG. All CCG group biochemical tests had significant increases (P Wistar rats caused hepatic dysfunction and biochemical and histological injuries with degrees of distortion to the hepatic architecture. Copyright © 2016 Elsevier Inc. All rights reserved.

'Charles River Associates analysis : impact of the world implementing the Kyoto Protocol : analysis of the impact on the Canadian upstream oil and gas industry of the global implementation of the Kyoto Protocol

International Nuclear Information System (INIS)

1999-09-01

A study was conducted to estimate the impacts on the Canadian oil and gas industry from the changes in demand for oil and natural gas fuels caused by implementation of the Kyoto Protocol throughout the Canadian economy. The multi-sector, multi-region trade (MS-MRT) model was used in the study. The MS-MRT was designed to study the effects of carbon restrictions on industrial output, trade and economic welfare in different regions of the world. An overview of the model was presented. The regions in the MS-MRT model are divided as follows: Canada; United States; European Union; Other OECD; Eastern Europe and Former Soviet Union; Non-OECD Asia; Mexico and OPEC; and all other countries. This paper also described how production, consumption and trade are modelled. The cases under which the impacts on the Canadian oil and gas sectors are modelled were also presented. refs., tabs., figs

Dissociation between spontaneously hypertensive (SHR) andWistar–Kyoto (WKY) rats in baseline performance and methylphenidate response on measures of attention, impulsivity and hyperactivity in a Visual Stimulus Position Discrimination Task

Energy Technology Data Exchange (ETDEWEB)

Thanos, P.K.

2009-10-08

The spontaneously hypertensive rat (SHR) is a widely accepted rodent model of Attention Deficit/Hyperactivity Disorder (ADHD), and methylphenidate (MP) is a central nervous systemstimulant that has been shown to have a dose-related positive effect on attention task performance in humans with ADHD. The current study was undertaken to compare SHR to its typical control strain, Wistar-Kyoto(WKY) rats, on the performance of a Visual Stimulus Position Discrimination Task (VSPDT) as well as of the responsiveness of the two rat strains to MP treatment. The rats were initially trained on the VSPDT, in which a light cue was presented randomly at three different cue-light intervals (1 s, 300 ms and 100 ms) over one of two levers, and presses on the lever corresponding to the light cue were reinforced with a food pellet. Once rats reached stable performance, the treatment phase of the study began, during which they received daily intraperitoneal (IP) injections of saline, 2 mg/kg, 5 mg/kg, and 10 mg/kg of MP in a randomized order immediately prior to being tested on the VSPDT. Baseline performance accuracy on the VSPDT did not differ between the groups. Furthermore, a striking strain dissociation was evident in the response of the two strains to treatment; VSPDT performance was substantially disrupted by the 5 and 10 mg/kg dose in the WKY rats but only mildly in the SHR rats. Response omissions were also increased only in WKY rats. Finally, both strains had increased locomotor activity in the operant chamber following MP treatment. These findings point to an important difference in response tendency toMP in the two strains that supports a view that a critical difference between these strains may suggest neurochemical and neuroadaptive differences associated with the behavioral impairments of ADHD.

Reactor laboratory course for Korean under-graduate students in Kyoto University Critical Assembly (KUGSiKUCA)

International Nuclear Information System (INIS)

Pyeon, Cheol Ho; Misawa, Tsuyoshi; Unesaki, Hironobu; Ichihara, Chihiro; Shiroya, Seiji; Whang, Joo Ho; Kim, Myung Hyun

2005-01-01

The Reactor Laboratory Course for Korean Under-Graduate Students has been carried out at Kyoto University Critical Assembly of Japan. This course has been launched from fiscal year 2003 and has been founded by Ministry of Science and Technology of Korean Government. Since then, the total number of 43 Korean under-graduate students, who have majored in nuclear engineering of 6 universities in all over the Korea, has been taken part in this course. The reactor physics experiments have been performed in this course, such as Approach to criticality, Control rod calibration, Measurement of neutron flux and power calibration, and Educational reactor operation. As technical tour of Japan, nuclear site tour has been taken during their stay in Japan, such as PWR, FBR, nuclear fuel company and some institutes

The Kyoto protocol - a victim of supply security? or: if Maslow were in energy politics

International Nuclear Information System (INIS)

Frei, Christoph W.

2004-01-01

History suggests that energy policy priorities can be stratified, similar to the way Maslow structured his famous pyramid of human needs. The essay below claims that access to energy, supply security, energy costs, environmental issues and social acceptance are not subject to trade-off, but to a hierarchy that underlies the importance of satisfying lower-order needs before addressing the higher-order needs. The essay demonstrates the hierarchy with an 'energy policy needs pyramid' based on historical evidence. The pyramid is used to analyze the viability of current items of the energy policy agenda. Conclusions indicate that the Kyoto protocol might be a victim of supply insecurity, that OPEC is good for the environment and that environmentalists should make the fight against energy poverty their first priority in order to achieve their overall goals

N.3663 report realized for the Foreign Affairs Commission on the law project n. 3274, authorizing the approbation of the agreement between France and United States of Mexico on the mechanism of clean development in the framework of the Kyoto protocol

International Nuclear Information System (INIS)

2007-02-01

The clean development mechanism is one of the Kyoto protocol flexible mechanisms. It is intended to allow industrialized countries to offset their greenhouse gas reduction targets by funding projects in developing countries that lead to reduced emissions. In this framework, this law project aims to favor the cooperation between France and Mexico. The first part presents the advantages of the Kyoto protocol and the second part is devoted to the bilateral cooperation. (A.L.B.)

Effects of enoxaparin and unfractionated heparin in prophylactic and therapeutic doses on the fertility of female Wistar rats.

Science.gov (United States)

Figueiró-Filho, Ernesto Antonio; Aydos, Ricardo Dutra; Senefonte, Flávio Renato de Almeida; Ferreira, Cristiane Munaretto; Pereira, Erica Freire de Vasconcelos; Oliveira, Vanessa Marcon de; Menezes, Giovanna Pádoa de; Bósio, Marco Antonio Costa

2014-07-01

To evaluate the effects of exposure of enoxaparin and unfractionated heparin (UFH) in prophylactic and therapeutic doses on the fertility rates of pregnant healthy Wistar rats. Enoxaparin and UFH were administered in prophylactic doses 1 mg/Kg/day 72 UI/Kg/day, and in therapeutic doses at 2 mg/kg/day 400UI/Kg/day. The rats were divided into five groups. The number of live and dead foetuses was quantified. The uterine horns were dissected and the presence of early and late reabsorptions (abortions) was determined. A peffect on fertility with the use of anticoagulant drugs in pregnant healthy Wistar rats.

Mécanisme pour un développement propre (MDP) du protocole de Kyoto: barrières et opportunités pour les pays moins avancés d'Afrique :cas du Burundi

OpenAIRE

Bisore, Simon

2012-01-01

Du Protocole de Kyoto est née une série d’objectifs de réduction des émissions de GES. Le respect de ces objectifs peut entraîner des coûts très lourds pour les économies des pays développés engagés dans la lutte contre les changements climatiques. Pour minimiser les coûts imposés par ces objectifs, des instruments économiques ont été développés, avec notamment la création de marchés du carbone. Y participent les trois mécanismes de flexibilité du Protocole de Kyoto parmi lesquels figure le M...

Reactivation of the Chagasic Infection in Wistar Rats in Gestation

OpenAIRE

Moreno B, Elio; Méndez I, Maidé; Alarcón M, Maritza; Araujo A, Sonia; Lugo de Yarbuh, Ana

2005-01-01

En este trabajo investigamos en ratas Wistar crónicamente infectadas con Trypanosoma cruzi, la reactivación de la infección durante la gestación y después del parto, mediante un estudio parasitológico, inmunológico, histopatológico e inmunohistoquímico. Los resultados mostraron un control de las parasitemias patentes y/o subpatentes; títulos elevados de anticuerpos específicos anti-T. cruzi, detectándose en las ratas gestantes una disminución en los niveles de IgG y un incremento significativ...

Climate Change and Employment in Europe. 'Kyoto' section. Country Report. Spain

Energy Technology Data Exchange (ETDEWEB)

Nussbaumer, P. [Universitat Autonoma de Barcelona ICTA, Barcelona (Spain); Belen Sanchez, A.; Riechmann, J. [ISTAS Instituto Sindical de Trabajo, Ambiente y Salud, Madrid (Spain)

2006-10-15

The results of an analysis of the effects of carbon dioxide emission mitigation policies and measures on the economic activity and employment in Spain are presented and discussed. The investigation is based on the review of the literature and on the results of a series of face-to-face interviews with selected stakeholders. Actors interviewed include representatives of public authorities, employers and employers' organisations, trade unions, and environmental NGOs. They are active in the following sectors: Energy, Industry, Transport, Building and Construction. Spain's lively economy experienced an important growth, exceeding the European average, in the last few years. Greenhouse gases emissions increased in all sectors in the recent years, making Spain the second European country the furthest away (+52% in 2005) from its Kyoto emission commitment (+15%) in absolute terms. Spain's Kyoto target will only be reachable with an extensive use of the flexible mechanisms. The Government, at national and regional level, put in place a comprehensive mix of Policies and Measures in order to curb down greenhouse gases emissions, the national Allocation Plan being the central element. Its design has been accompanied by a notable social consultation process, which includes trade unions and companies representatives. Other important Policies and Measures are the Strategy for Energy Savings and Energy Efficiency, the Renewable Energy Plan, and the Strategic Infrastructures and Transport Plan. The impact on employment of greenhouse gases mitigation Policies and Measures is generally perceived as minor by the interviewees. Nevertheless, some fields, such as Renewable Energy for instance, could see their activity enhanced by such policies. In the same way, cost-benefit analyses of energy efficiency measures commonly conclude to a net positive balance in terms of employment. Some fear for employment in the coal sector as a shift away from conventional energy is

Comparative morphophysiological evaluation of the testis of adult Wistar rats fed low protein-energy diet and dosed with aqueous extracts of Cuscuta australis.

Science.gov (United States)

Ozegbe, P C; Omirinde, J O

2012-12-18

Cuscuta australis (C. australis) seed and stem are historically used by the local population as dietary supplement for the management of infertility. This study, therefore, evaluated the effect of orally administered aqueous extracts of C. australis seed and stem, 300 mg/kg body weight/day for seven days, on the testis of the adult Wistar rat fed either low or normal protein-energy diets. The control group received water. The relative weight of the testis was non-significantly increased (p>0.05) in the Low Protein-energy diet-Water-treated (LPWA), Low Protein-energy diet-Seed-treated (LPSE) and Normal Protein-energy diet-Seed-treated (NPSE) groups relative to the Normal Protein-energy diet-Water-treated (NPWA). The weight of the testis was also non-significantly increased (p˃0.05) in the Low Protein-energy diet-Stem-treated (LPST), but decreased in the Normal Protein-energy diet-Stem-treated (NPST), relative to LPWA and NPWA. Heights of germinal epithelium were significantly decreased (p<0.05) in the LPWA, LPSE and LPST relative to the NPWA, NPSE and NPST. Diet significantly influenced (p<0.001) the effect of stem extract on the height of germinal epithelium. The NPSE, LPSE, NPST, LPST and LPWA showed significantly decreased (p<0.001) plasma levels of luteinizing hormone (LH) and follicle stimulating hormone (FSH) relative to NPWA. The LPWA, LPSE and NPST also showed significantly decreased (p<0.001) levels of testosterone relative to NPWA and LPST. Diet significantly influenced (p<0.001) the effect of seed on the level of LH. Seed-diet interactions significantly affected the levels of FSH (p<0.001) and LH (p<0.05), but not testosterone. Diet significantly influenced (p<0.001) the effects of stem extract on the levels of FSH, LH and testosterone. Stem-diet interactions significantly affected (p<0.001) the levels of FSH, LH and testosterone. Our data suggest that the aqueous extract of C. australis stem is more potent than the seed extract and that dietary protein

Effect Of Polyphenols Klika Ongkea Mezzetia Parviflora Becc Against Blood Glucose Wistar Rats Induced By Streptozotocin

Directory of Open Access Journals (Sweden)

Jangga

2015-04-01

Full Text Available Abstract When this has been developed medicines from natural ingredients to control diabetes mellitus most of these materials have been studied and shown to be effective as an alternative therapy. This study aimed to determine the effect of polyphenols Klika ongkea Mezzetia parviflora Becc. To decrease blood glucose levels induced streptozotosin wistar rats STZ and to determine the concentration of how the effect is not significantly different from the control group of drugs. In this study used Wistar rats were 120 tails are divided into six treatment groups the first group of healthy controls were given Na. CMC 1 group II were given pain control STZ 40 mg kg body weight of mice group III was given the drug control galvus vildagliptin group IV V and VI are given polyphenols Klika ongkea each 100mg kg and 300mg kg for 21 day. The results showed that administration of polyphenols Klika ongkea 300mg kg body weight of rats and 300 mg kg body weight of mice as a protective effect on the decreased levels of blood glucose Wistar rats induced by STZ and giving polyphenols Klika ongkea 300mg kg body weight of rats and 300 mg kg rat as protective effect was not significantly different the effect of galvus vildagliptin 0.9 mg 200 gBW mice.

Performance of the 100 MeV injector linac for the electron storage ring at Kyoto University

International Nuclear Information System (INIS)

Shirai, T.; Sugimura, T.; Iwashita, Y.; Kakigi, S.; Fujita, H.; Tonguu, H.; Noda, A.; Inoue, M.

1996-01-01

An electron linear accelerator has been constructed as an injector of a 300 MeV electron storage ring (Kaken Storage Ring, KSR) at Institute for Chemical Research, Kyoto University. The output beam energy of the linac is 100 MeV and the designed beam current is 100 mA at the 1 μsec long pulse mode. The transverse and longitudinal emittance are measured to evaluate the beam quality for the beam injection into the KSR. They are observed by the profile monitors combined with quadrupole magnets or an RF accelerator. The results are that the normalized transverse emittance is 120 π.mm.mrad. The longitudinal emittance is 15 π.deg.MeV and the energy spread is ±2.2 %. (author)

LOS DERECHOS DE EMISIÓN COMO INSTRUMENTO PARA ALCANZAR KYOTO: EL CASO DEL SECTOR ELÉCTRICO

Directory of Open Access Journals (Sweden)

Yolanda Fernández Fernández

2008-06-01

Full Text Available The signature of the Kyoto’s Protocol has the aim to reduce greenhouse gas emissions, through several instruments as the market of emission rights. Each European Estate must publish the amount of rights that are assigned to each sector. In the case of Spain, this is published in the “Plan Nacional de Asignación (PNA de Derechos de Emisión”.The aim of this work is to review the "Emission trading system" as an instrument in order to fulfil the Kyoto Protocol and its influence on the offer of electricity. In addition, we will analyse the government response to the electric industry related to the concession of new “emission rights” in the new 2008-2012 Plan.

A study of the effects of oral contraceptives on plasma urea of Wistar ...

African Journals Online (AJOL)

Oral contraceptives such as Microgynon a combined pill (0.15mg levonorgestrel and 0.03mg ethinylestradiol) and Primolut -N a mini pill (5mg norethisterone) were investigated for their in-vivo effects on wistar albino rat rattus rattus plasma urea levels. Test results showed that the drugs had a lowering effect on plasma urea ...

Effect of Grape Seed Extract on Lipid Profile and Expression of Interleukin-6 in Polycystic Ovarian Syndrome Wistar Rat Model

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Zohreh Salmabadi

2017-09-01

Full Text Available Background Polycystic ovary syndrome (PCOS is a common but complex endocrine disorder and is the major cause of anovulation and consequent subfertility. In this study the effect of grape seed extract (GSE on triglyceride (TG, total cholesterol (TC, highdensity lipoprotein-cholestrol (HDL-C, low-density lipoprotein-cholestrol (LDL-C and interleukin-6 (IL-6 in PCOS Wistar rats were assessed. Materials and Methods In this experimental study, 84 adult female Wistar rats were divided into 7 groups (n=12 including control (intact, Sham (estradiol valerate solvent injection, control PCOS and 4 experimental PCOS groups. To induce the syndrome, a single subcutaneous injection of 2 mg estradiol valerate was applied. In experimental groups, PCOS rats were treated with different doses of 50, 75, 100 and 200 mg/kg body weight (BW GSE by intraperitoneal injection for 10 consecutive days. After harvesting blood serum, TG was measured by Glycerol-3-phosphate Oxidase-Peoxidase (GPO- PAP, TC by Cholesterol Oxidase-Peroxidase (CHOD-PAP, and HDL-C by sedimentation method, LDL-C by Friedwald calculation and IL-6 by ELISA method. The serum values of each parameter were analyzed using one-way ANOVA at P≤0.05. Results In all experimental groups significant decrease of visceral fat was obvious as compared with control PCOS group. LDL-C, TC and IL-6 levels in experimental groups, particularly at dose of 50 mg/kg of GSE, were significantly decreased as compared with PCOS group. However, HDL-C levels were not significantly changed. Conclusion : According to the findings of this study, it can be concluded that GSE with its effects on serum TC, LDL-C and IL-6 could reduce the effects of dyslipidemia and inflammation in PCOS rats and improve systemic symptoms of PCOS.

Progress of German climate change policies until 2020. Report of the German Government for the assessment of projected progress in accordance with the implementation of the Kyoto Protocol - reporting in compliance to article 3(2) EU Directive 280/2004. Final report; Wirksamkeit des Klimaschutzes in Deutschland bis 2020. Bericht der Bundesregierung zur Bewertung des voraussichtlichen Fortschritts der Bundesrepublik Deutschland 2007 gemaess Umsetzung des Kyoto-Protokolls - Berichterstattung nach Artikel 3 Absatz 2 der EU-Richtlinie 280/2004. Endfassung

Energy Technology Data Exchange (ETDEWEB)

Erdmenger, Christoph; Kuhnhenn, Kai; Maue, Georg; Mayr, Sebastian (comps.)

2008-03-15

The report of the German Government on the projected progress in accordance with the implementation of the Kyoto Protocol with respect ton the progress of German climate policy until 2020 covers the following chapters: comparison of the scenarios without and with measures: description of the measures and instruments implemented in Germany and quantification of their efficacy (energy management, industry, commerce, trade, private households, traffic, agriculture, forestry); scenario with further measures: description of possible further measures and instruments for climate protection and quantification of their expected impacts; institutional measures and instrument concerning the Kyoto protocol; measures for participation in flexible mechanisms.

Saccharin and aspartame, compared with sucrose, induce greater weight gain in adult Wistar rats, at similar total caloric intake levels.

Science.gov (United States)

Feijó, Fernanda de Matos; Ballard, Cíntia Reis; Foletto, Kelly Carraro; Batista, Bruna Aparecida Melo; Neves, Alice Magagnin; Ribeiro, Maria Flávia Marques; Bertoluci, Marcello Casaccia

2013-01-01

It has been suggested that the use of nonnutritive sweeteners (NNSs) can lead to weight gain, but evidence regarding their real effect in body weight and satiety is still inconclusive. Using a rat model, the present study compares the effect of saccharin and aspartame to sucrose in body weight gain and in caloric intake. Twenty-nine male Wistar rats received plain yogurt sweetened with 20% sucrose, 0.3% sodium saccharin or 0.4% aspartame, in addition to chow and water ad libitum, while physical activity was restrained. Measurements of cumulative body weight gain, total caloric intake, caloric intake of chow and caloric intake of sweetened yogurt were performed weekly for 12 weeks. Results showed that addition of either saccharin or aspartame to yogurt resulted in increased weight gain compared to addition of sucrose, however total caloric intake was similar among groups. In conclusion, greater weight gain was promoted by the use of saccharin or aspartame, compared with sucrose, and this weight gain was unrelated to caloric intake. We speculate that a decrease in energy expenditure or increase in fluid retention might be involved. Copyright © 2012 Elsevier Ltd. All rights reserved.

Effect of prebiotics of Agave salmiana fed to healthy Wistar rats.

Science.gov (United States)

Jasso-Padilla, Iliana; Juárez-Flores, Bertha; Alvarez-Fuentes, Gregorio; De la Cruz-Martínez, Alejandro; González-Ramírez, José; Moscosa-Santillán, Mario; González-Chávez, Marco; Oros-Ovalle, Cuauhtemoc; Prell, Florian; Czermak, Peter; Martinez-Gutierrez, Fidel

2017-01-01

Inulin and other fructans are synthesized and stored in mezcal agave (Agave salmiana). Fructans provide several health benefits and have excellent technological properties, but only few data report their physiological effect when added in the diet. Here, we studied the physiological effects of fructans obtained from A. salmiana when added in the diet of Wistar rats. Results showed favorable changes on Wistar rats when the fructans was added to their diet, including the decrease of the pH in the feces and the increase of the number of lactic acid bacteria (CFU g -1 ) (Lactobacillus spp. and Bifidobacterium spp.), even these changes were enhanced with the synbiotic diet (fructans plus B. animalis subsp. lactis). Synbiotic diet, developed changes in the reduction of cholesterol and triglycerides concentrations in serum, with statistical differences (P < 0.05). Histological analysis of colon sections showed that synbiotic diet promoted colon cells growth suggesting that fructans from A. salmiana confer beneficial health effects through gut microbiota modulation. Our data underline the advantage of targeting the gut microbiota by colonic nutrients like specific structure of fructans from A. salmiana, with their beneficial effects. More studies are necessary to define the role of fructans to develop more solid therapeutic solutions in humans. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

Present status of operation and utilization of Kyoto University Reactor, KUR

International Nuclear Information System (INIS)

Kimura, Itsuro

1988-01-01

The Research Reactor Institute was established as an inter-university research institute in 1963. The main installation of the Institute is the KUR, a light water moderated, tank type reactor of 5,000 kW. In addition, a 46 MeV electron linear accelerator and a gamma ray irradiation facility with 10,000 Ci Co-60 are actively used for research. In 1974, Kyoto University Critical Assembly (KUCA) was constructed, and it has been used for research and education. The Reactor Utilization Center and the Fundamental Research Laboratory for Neutron Therapy were established in 1975 and 1976, respectively. Approximately 200 people work there, of them, some 80 do research and education, including 13 professors and 12 associate professors. All the experimental facilities of the Institute are available for the cooperative research projects of other universities and public research institutions in the fields of natural science and engineering, medical science, agriculture and forestry, fishery and stock-raising, environment science, cultural science and others. As a rule, the KUR is operated for about 70 hours from Tuesday morning to Friday evening every week. The annual examination by the government is carried out in spring. The total operation time was about 45,000 hours as of the end of 1987. The recent topics are reported. (Kako, I.)

Supplier-dependent differences in intermittent voluntary alcohol intake and response to naltrexone in Wistar rats

Directory of Open Access Journals (Sweden)

Shima eMomeni

2015-11-01

Full Text Available Alcohol use disorder (AUD is a worldwide public health problem and a polygenetic disorder displaying substantial individual variation. This work aimed to study individual differences in behavior and its association to voluntary alcohol intake and subsequent response to naltrexone in a seamless heterogenic group of animals. Thus, by this approach the aim was to more accurately recapitulate the existing heterogeneity within the human population. Male Wistar rats from three different suppliers (Harlan Laboratories B.V., RccHanTM:WI; Taconic Farms A/S, HanTac:WH; and Charles River GmbH, Crl:WI were used to create a heterogenic group for studies of individual differences in behavior, associations to intermittent voluntary alcohol intake and subsequent response to naltrexone. The rats were tested in the open field prior to the Y-maze and then given voluntary intermittent access to alcohol or water in the home cage for six weeks, where after, naltrexone in three different doses or saline was administered in a Latin square design over four weeks and alcohol intake and preference was measured. However, supplier-dependent differences and concomitant skew subgroup formations, primarily in open field behavior and intermittent alcohol intake, resulted in a shifted focus to instead study voluntary alcohol intake and preference, and the ensuing response to naltrexone in Wistar rats from three different suppliers. The results showed that outbred Wistar rats are diverse with regard to voluntary alcohol intake and preference in a supplier-dependent manner; higher in RccHanTM:WI relative to HanTac:WH and Crl:WI. The results also revealed supplier-dependent differences in the effect of naltrexone that were dose- and time-dependent; evident differences in high-drinking RccHanTM:WI rats relative to HanTac:WH and Crl:WI rats. Overall these findings render RccHanTM:WI rats more suitable for studies of individual differences in voluntary alcohol intake and response to