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Sample records for additional delayed regional

  1. Network Delay Inference from Additive Metrics

    Bhamidi, Shankar; Rajagopal, Ram; Roch, Sebastien

    2006-01-01

    We demonstrate the use of computational phylogenetic techniques to solve a central problem in inferential network monitoring. More precisely, we design a novel algorithm for multicast-based delay inference, i.e. the problem of reconstructing the topology and delay characteristics of a network from end-to-end delay measurements on network paths. Our inference algorithm is based on additive metric techniques widely used in phylogenetics. It runs in polynomial time and requires a sample of size ...

  2. Delayed radiation necrosis in the optochiasmatic region

    Two cases with delayed radiation necrosis of the chiasmatic region following irradiation of the hypophysis for treatment of Cushing's disease were presented. Case 1 was a 36-year-old female who had reduction of visual acuity and bitemporal hemianopsia 2 years after 60Co-irradiation therapy (total 8000 rads) for Cushing's disease. CT scans showed low density in the pituitary fossa and irregular contrast-enhanced suprasellar mass, and metrizamide CT cisternography revealed the pituitary fossa filled with contrast medium. From those findings, secondary empty sella syndrome was suspicious. Case 2 was a 35-year-old male who had progressive visual disturbance 3 years after 60Co-irradiation therapy (total 9050 rads) for Cushing's disease. The right visual acuity was 0.05 and the left one was 0.1. Examination of visual field showed left homonymous hemianopsia. CT scans showed the contrast enhanced suprasellar mass extending to the right anterior thalamic region, and metrizamide CT cisternography detected secondary empty sella as same as that of Case 1. Authors reviewed and analyzed literatures of delayed radiation necrosis. The incidence of this condition was 4% to 9% and onset of the symptoms occured approximately 2 years after irradiation to hypophysis. Administration of steroid hormone and surgical treatment for the radiation necrosis involving the chiasmatic region were almost ineffective and also the prognosis of radionecrotic lesions involving the hypothalamus was very poor. Therefore, radiotherapy for hypophyseal region must be carried out by means of a rotation or arching technique in order to avoid this condition and further total dosage and its fractionation in radiation therapy should not exceed 6000 rads and 200 rads a day. (J.P.N.)

  3. Delayed imaging and additional methods to reduce subdiaphragmatic activity in myocardial perfusion SPECT imaging

    Wosnitzer, Brian; Ata, Pashmina; DePuey, Ernest Gordon

    2015-01-01

    Compton scatter from radiotracer in structures close to the heart may partially or completely mask myocardial perfusion defects on SPECT imaging. Previous reports have discussed benefits of additional delayed imaging. We present a case in which additional delayed stress imaging reduced Compton scatter and unveiled clinically significant, stress-induced ischemia.

  4. Passivity and Passification of Memristor-Based Recurrent Neural Networks With Additive Time-Varying Delays.

    Rakkiyappan, Rajan; Chandrasekar, Arunachalam; Cao, Jinde

    2015-09-01

    This paper presents a new design scheme for the passivity and passification of a class of memristor-based recurrent neural networks (MRNNs) with additive time-varying delays. The predictable assumptions on the boundedness and Lipschitz continuity of activation functions are formulated. The systems considered here are based on a different time-delay model suggested recently, which includes additive time-varying delay components in the state. The connection between the time-varying delay and its upper bound is considered when estimating the upper bound of the derivative of Lyapunov functional. It is recognized that the passivity condition can be expressed in a linear matrix inequality (LMI) format and by using characteristic function method. For state feedback passification, it is verified that it is apathetic to use immediate or delayed state feedback. By constructing a Lyapunov-Krasovskii functional and employing Jensen's inequality and reciprocal convex combination technique together with a tighter estimation of the upper bound of the cross-product terms derived from the derivatives of the Lyapunov functional, less conventional delay-dependent passivity criteria are established in terms of LMIs. Moreover, second-order reciprocally convex approach is employed for deriving the upper bound for terms with inverses of squared convex parameters. The model based on the memristor with additive time-varying delays widens the application scope for the design of neural networks. Finally, pertinent examples are given to show the advantages of the derived passivity criteria and the significant improvement of the theoretical approaches. PMID:25415991

  5. Formation of "delayed risks" in regional innovative production

    Olga Avdeychik

    2014-02-01

    Full Text Available The article considers specific features of functioning of regional complexes within the framework of joint realization of both Sustainable Development Concept and an innovation strategy which provides a synergistic result of achieving optimal economic parameters while minimizing negative anthropogenic impact on the environment. Violation of the optimal equilibrium in the simultaneous implementation of both strategies increases the probability of manifestation of environmental and economic risks and economic risks, due to increasing share of waste at different stages of life cycle of industrial products with a predominant innovation component. Disproportions in the implementation of modern approaches to innovations functioning with regard to regional specifics of sustainable development increase adverse effects on the ecosystem. Forming a background of delayed technologic and environmental risk, they increase the likelihood of economic risk, reducing the effectiveness of already implemented innovations. An effective strategy for minimization of delayed risks to different species is the formation of regional cluster structures which include industrial, managerial, research and training components based on integration of intellectual, material and technological resources.

  6. Regional White Matter Volumes Correlate with Delay Discounting

    Yu, Rongjun

    2012-01-01

    A preference for immediate gratification is a central feature in addictive processes. However, the neural structures underlying reward delay tolerance are still unclear. Healthy participants (n = 121) completed a delay discounting questionnaire assessing the extent to which they prefer smaller immediate rewards to larger delayed reward after undergoing magnetic resonance imaging (MRI) scanning. Whole brain voxel-based morphometric analysis shows that delay discounting severity was negatively ...

  7. Regional white matter volumes correlate with delay discounting.

    Rongjun Yu

    Full Text Available A preference for immediate gratification is a central feature in addictive processes. However, the neural structures underlying reward delay tolerance are still unclear. Healthy participants (n = 121 completed a delay discounting questionnaire assessing the extent to which they prefer smaller immediate rewards to larger delayed reward after undergoing magnetic resonance imaging (MRI scanning. Whole brain voxel-based morphometric analysis shows that delay discounting severity was negatively correlated with right prefrontal subgyral white matter volume and positively correlated with white matter volume in parahippocampus/hippocampus, after whole brain correction. This study might better our understanding of the neural basis of impulsivity and addiction.

  8. STUDY OF INJECTION TRAMADOL AS ADDITIVE IN INTRAVENOUS REGIONAL ANESTHESIA

    Rajesh

    2015-10-01

    is no effect of Tramadol on onset of motor blocked in both the group. In post - operative period the need of analgesic is delayed in group 2 which is statistically significant.( p value is 0.00001 We observe post - oper ative nausea and vomiting events more in group - 1(24% and in group - 2 (16 % but there isno statistical difference. Pain is the significant factor for post - operative nausea and vomiting. Group 2 patients (Tramadol group are more comfortable with tourniquet intra - operatively but statistically it is not significant. Intraoperative discomfort may attribute to anxiety and fear along with possibility of dilution of drugs because of inadequate exsanguination . CONCLUSION : We conclude that addition of injection Tra madol 50mg in intravenous regional anesthesia will improve the onset of sensory blockade and improves the post - operative analgesia without any increase of postoperative nausea and vomiting. Also it is concluded that injection Tramadol has no effect on moto r blocked.

  9. Mixed butanols addition to gasoline surrogates: Shock tube ignition delay time measurements and chemical kinetic modeling

    AlRamadan, Abdullah S.

    2015-10-01

    The demand for fuels with high anti-knock quality has historically been rising, and will continue to increase with the development of downsized and turbocharged spark-ignition engines. Butanol isomers, such as 2-butanol and tert-butanol, have high octane ratings (RON of 105 and 107, respectively), and thus mixed butanols (68.8% by volume of 2-butanol and 31.2% by volume of tert-butanol) can be added to the conventional petroleum-derived gasoline fuels to improve octane performance. In the present work, the effect of mixed butanols addition to gasoline surrogates has been investigated in a high-pressure shock tube facility. The ignition delay times of mixed butanols stoichiometric mixtures were measured at 20 and 40bar over a temperature range of 800-1200K. Next, 10vol% and 20vol% of mixed butanols (MB) were blended with two different toluene/n-heptane/iso-octane (TPRF) fuel blends having octane ratings of RON 90/MON 81.7 and RON 84.6/MON 79.3. These MB/TPRF mixtures were investigated in the shock tube conditions similar to those mentioned above. A chemical kinetic model was developed to simulate the low- and high-temperature oxidation of mixed butanols and MB/TPRF blends. The proposed model is in good agreement with the experimental data with some deviations at low temperatures. The effect of mixed butanols addition to TPRFs is marginal when examining the ignition delay times at high temperatures. However, when extended to lower temperatures (T < 850K), the model shows that the mixed butanols addition to TPRFs causes the ignition delay times to increase and hence behaves like an octane booster at engine-like conditions. © 2015 The Combustion Institute.

  10. Influence of Biofuel Additions on the Ignition Delay of Single Diesel Fuel Drops

    Kopeika, A. K.; Golovko, V. V.; Zolotko, A. N.; Raslavičius, L.; Lubarskii, V. M.

    2015-07-01

    The behavior of single drops of two- and three-component mineral diesel fuel blends with ethanol and rapeseed oil methyl ester in a heated atmosphere has been investigated. With the use of the known quasi-stationary approach, the influence of the thermal properties of fuel blend components and their composition on the ignition delay time of the drop has been investigated. It has been established that under inert heating conditions of the drop, additions of low-boiling ethanol to diesel fuel should shorten the duration of the preignition period, and additions of rapeseed oil methyl ester should, on the contrary, prolong it. Analysis of the obtained data has made it possible to determine the optimal composition of the fuel blend for the most economical operation of the diesel. The prognostic estimates made are confirmed by laboratory experiments and bench tests of fuel blends.

  11. Identification and systematical studies of the electron-capture delayed fission (ECDF) in the lead region

    Pauwels, D B; Lane, J

    2008-01-01

    In our recent experiment (March 2007) at the velocity filter SHIP(GSI) we observed the electron-capture delayed fission of the odd-odd isotope $^{194}$At. This is the first unambiguous identification of this phenomenon in the very neutron-deficient nuclei in the vicinity of the proton shell closure at Z=82. In addition, the total kinetic energy (TKE) for the daughter nuclide $^{194}$Po was measured, despite the fact that this isotope does not decay via spontaneous fission. Semi-empirical analysis of the electron-capture Q$_{EC}$ values and fission barriers B$_{f}$ shows that a relatively broad island of ECDF must exist in this region of the Nuclide Chart, with some of the nuclei having unusually high ECDF probabilities. Therefore, this Proposal is intended to initiate the systematic identification and study of $\\beta$-delayed fission at ISOLDE in the very neutron-deficient lead region. Our aim is to provide unique low-energy fission data (e.g. probabilities, TKE release, fission barriers and their isospin dep...

  12. Bifurcation behaviors of synchronized regions in logistic map networks with coupling delay

    Network synchronized regions play an extremely important role in network synchronization according to the master stability function framework. This paper focuses on network synchronous state stability via studying the effects of nodal dynamics, coupling delay, and coupling way on synchronized regions in Logistic map networks. Theoretical and numerical investigations show that (1) network synchronization is closely associated with its nodal dynamics. Particularly, the synchronized region bifurcation points through which the synchronized region switches from one type to another are in good agreement with those of the uncoupled node system, and chaotic nodal dynamics can greatly impede network synchronization. (2) The coupling delay generally impairs the synchronizability of Logistic map networks, which is also dominated by the parity of delay for some nodal parameters. (3) A simple nonlinear coupling facilitates network synchronization more than the linear one does. The results found in this paper will help to intensify our understanding for the synchronous state stability in discrete-time networks with coupling delay

  13. An LMI Approach to H∞ Performance Analysis of Continous-Time System with Two Additive Time-Varying Delays

    Wrastawa Ridwan

    2011-08-01

    Full Text Available This paper investigates the problem of H∞ performance analysis for continous–time systems with two additive time-varying delays in the state. Our objective is focused on stability analysis of a continuous system with two time-varying delays with an H∞ disturbance attenuation level γ. By exploiting Lyapunov-Krasovski functional and introducing free weighting matrix variables, LMI stability condition have been derived.

  14. Delayed Adrenarche may be an Additional Feature of Immunoglobulin Super Family Member 1 Deficiency Syndrome.

    Hulle, Severine Van; Craen, Margarita; Callewaert, Bert; Joustra, Sjoerd; Oostdijk, Wilma; Losekoot, Monique; Wit, Jan Maarten; Turgeon, Marc Olivier; Bernard, Daniel J; Schepper, Jean De

    2016-03-01

    Immunoglobulin super family member 1 (IGSF1) deficiency syndrome is characterized by central hypothyroidism, delayed surge in testosterone during puberty, macro-orchidism, and in some cases, hypoprolactinemia and/or transient growth hormone (GH) deficiency. Our patient was a 19-year-old male adolescent who had been treated since the age of 9 years with GH and thyroxine for an idiopathic combined GH, thyroid-stimulating hormone (TSH), and prolactin (PRL) deficiency. His GH deficiency proved to be transient, but deficiencies of TSH and PRL persisted, and he had developed macro-orchidism since the end of puberty. Brain magnetic resonance imaging and PROP1 and POU1F1 sequencing were normal. A disharmonious puberty (delayed genital and pubic hair development, bone maturation, and pubertal growth spurt, despite normal testicular growth) was observed as well as a delayed adrenarche, as reflected by very low dehydroepiandrosterone sulfate and delayed pubarche. Direct sequencing of the IGSF1 gene revealed a novel hemizygous mutation, c.3127T>C, p.Cys1043Arg. Pathogenicity of the mutation was demonstrated in vitro. Male children with an idiopathic combined GH, PRL, and TSH deficiency, showing persistent central hypothyroidism but transient GH deficiency upon retesting at adult height, should be screened for mutations in the IGSF1 gene, especially when macro-orchidism and/or hypoprolactinemia are present. We suspect that delayed adrenarche, as a consequence of PRL deficiency, might be part of the clinical phenotype of patients with IGSF1 deficiency. PMID:26757742

  15. Stability Region Analysis of PID and Series Leading Correction PID Controllers for the Time Delay Systems

    D. RAMA REDDY

    2012-07-01

    Full Text Available This paper describes the stability regions of PID (Proportional +Integral+ Derivative and a new PID with series leading correction (SLC for Networked control system with time delay. The new PID controller has a tuning parameter ‘β’. The relation between β, KP, KI and KD is derived. The effect of plant parameters on stabilityregion of PID controllers and SLC-PID controllers in first-order and second-order systems with time delay are also studied. Finally, an open-loop zero was inserted into the plant-unstable second order system with time delay so that the stability regions of PID and SLC-PID controllers get effectively enlarged. The total system isimplemented using MATLAB/Simulink.

  16. Reduction in Delayed Gastric Emptying Following Non-Pylorus Preserving Pancreaticoduodenectomy by Addition of a Braun Enteroenterostomy

    Mehrdad Nikfarjam

    2012-09-01

    Full Text Available Context Delayed gastric emptying is a major cause of morbidity following pancreaticoduodenectomy. Objective The impact of a Braun enteroenterostomy on delayed gastric emptying, used in reconstruction following classic pancreaticoduodenectomy, was assessed. Patients Forty-four consecutive patients undergoing non-pylorus preserving pancreaticoduodenectomy from 2009 to 2011 by a single surgeon were included in this study. Interventions The first 20 patients had a standard antecolic gastroenterostomy and the subsequent 24 had the addition of a Braun enteroenterostomy. Results Patient characteristics, the extent of surgery, surgical findings and tumor characteristics were similar between the two groups. The delayed gastric emptying rate in the Braun enteroenterostomy (1/24, 4.2% was significantly lower (P=0.008 than the standard reconstruction group (7/20, 35.0%. In the standard group, 6 of 7 cases (85.7% of delayed gastric emptying were class C in nature. After exclusion of 8 total pancreatectomy patients, the pancreatic fistula rate in the Braun enteroenterostomy group (4/19, 21.1% was similar (0.706 to the standard reconstruction group (5/17, 29.4% as was the median length of hospital stay (10 days vs. 15 days; P=0.291. Braun enteroenterostomy technique was the only significant independent factor associated with reduced delayed gastric emptying with an odds ratio of 0.08 (95% confidence interval: 0.01-0.73; P=0.025. Conclusion The use of Braun enteroenterostomy following nonpylorus preserving pancreaticoduodenectomy appears to result in a significant reduction in delayed gastric emptying.

  17. Delayed onset of tricuspid valve flow in repaired tetralogy of Fallot: an additional mechanism of diastolic dysfunction and interventricular dyssynchrony

    Benson Lee N

    2011-08-01

    Full Text Available Abstract Background Diastolic dysfunction of the right ventricle (RV is common after repair of tetralogy of Fallot. While restrictive physiology in late diastole has been well known, dysfunction in early diastole has not been described. The present study sought to assess the prevalence and mechanism of early diastolic dysfunction of the RV defined as delayed onset of the tricuspid valve (TV flow after TOF repair. Methods The study population consisted of 31 children with repaired TOF (mean age ± SD, 12.3 ± 4.1 years who underwent postoperative cardiovascular magnetic resonance (CMR. The CMR protocol included simultaneous phase-contrast velocity mapping of the atrioventricular valves, which enabled direct comparison of the timing and patterns of tricuspid (TV and mitral (MV valve flow. The TV flow was defined to have delayed onset when its onset was > 20 ms later than the onset of the MV flow. The TV and MV flow from 14 normal children was used for comparison. The CMR results were correlated with the findings on echocardiography and electrocardiography. Result Delayed onset of the TV flow was observed in 16/31 patients and in none of the controls. The mean delay time was 64.81 ± 27.07 ms (8.7 ± 3.2% of R-R interval. The delay time correlated with the differences in duration of the TV and MV flow (55.94 ± 32.88 ms (r = 0.90, p Conclusions Early diastolic dysfunction with delayed onset of TV flow is common after TOF repair, and is associated with reduced RV ejection fraction. It is a further manifestation of interventricular dyssynchrony and represent an additional mechanism of ventricular diastolic dysfunction.

  18. Evaluation Study for Delay and Link Utilization with the New-Additive Increase Multiplicative Decrease Congestion Avoidance and Control Algorithm

    Jasem, Hayder Natiq; Othman, Mohamed; Subramaniam, Shamala

    2010-01-01

    As the Internet becomes increasingly heterogeneous, the issue of congestion avoidance and control becomes ever more important. And the queue length, end-to-end delays and link utilization is some of the important things in term of congestion avoidance and control mechanisms. In this work we continue to study the performances of the New-AIMD (Additive Increase Multiplicative Decrease) mechanism as one of the core protocols for TCP congestion avoidance and control algorithm, we want to evaluate the effect of using the AIMD algorithm after developing it to find a new approach, as we called it the New-AIMD algorithm to measure the Queue length, delay and bottleneck link utilization, and use the NCTUns simulator to get the results after make the modification for the mechanism. And we will use the Droptail mechanism as the active queue management mechanism (AQM) in the bottleneck router. After implementation of our new approach with different number of flows, we expect the delay will less when we measure the delay ...

  19. Diagnostic and treatment delay among Tuberculosis patients in Afar Region, Ethiopia: A cross-sectional study

    Belay Mulugeta

    2012-05-01

    Full Text Available Abstract Background TB is a major public health problem globally and Ethiopia is 8th among the 22 high burden countries. Early detection and effective treatment are pre-requisites for a successful TB control programme. In this regard, early health seeking action from patients’ side and prompt diagnosis as well as initiation of treatment from the health system’s side are essential steps. The aim of this study was to assess delay in the diagnosis and treatment of TB in a predominantly pastoralist area in Ethiopia. Methods On a cross-sectional study, two hundred sixteen TB patients who visited DOTS clinics of two health facilities in Afar Region were included consecutively. Time from onset of symptoms till first consultation of formal health providers (patients’ delay and time from first consultation till initiation of treatment (health system’s delay were analyzed. Results The median patients’ and health system’s delay were 20 and 33.5 days, respectively. The median total delay was 70.5 days with a median treatment delay of 1 day. On multivariate logistic regression, self-treatment (aOR. 3.99, CI 1.50-10.59 and first visit to non-formal health providers (aOR. 6.18, CI 1.84-20.76 were observed to be independent predictors of patients’ delay. On the other hand, having extra-pulmonary TB (aOR. 2.08, CI 1.08- 4.04, and a first visit to health posts/clinics (aOR. 19.70, CI 6.18-62.79, health centres (aOR. 4.83, CI 2.23-10.43 and private health facilities (aOR. 2.49, CI 1.07-5.84 were found to be independent predictors of health system’s delay. Conclusions There is a long delay in the diagnosis and initiation of treatment and this was mainly attributable to the health system. Health system strengthening towards improved diagnosis of TB could reduce the long health system’s delay in the management of TB in the study area.

  20. Calibration of regional ionospheric delay with uncombined precise point positioning and accuracy assessment

    Li Wei; Cheng Pengfei; Bei Jinzhong; Wen Hanjiang; Wang Hua

    2012-08-01

    A new method for the calibration of regional ionospheric delay based on uncombined precise point positioning (U-PPP) is proposed in this study. The performance of the new method was comparatively validated in terms of its accuracy and robustness with respect to the phase-smoothed pseudorange (PSP) method through two short-baseline experiments. Accuracy of the PPP-derived ionospheric delays was further assessed by interpolating them to a user station to perform single-frequency simulated kinematic PPP. Two 24-hr period datasets of four continuous operation reference system (CORS) stations were analyzed, collected during calm and disturbed ionospheric conditions, respectively. The single-frequency GPS observables from a user station, that were a-priori corrected by the interpolated ionospheric delays, were utilized to implement single-frequency PPP (SF-PPP). The results show that interpolation accuracy is better than 1 dm and, with the proposed method, is less affected by the ionospheric activity; meanwhile, positioning accuracy of SF-PPP was 4 ∼5 cm (horizontal) and better than 1 dm (vertical). For comparison, two reference SF-PPP solutions were also obtained, in which the ionospheric delays are eliminated either by forming semi-combination observations or by using global ionosphere maps (GIM) model values; in both cases the positioning accuracy was only 4 ∼7 dm (horizontal) and 1 m (vertical). These results provide a further demonstration of the performance of PPP-based regional ionospheric calibration in the parameter domain.

  1. Effects of delayed treatment with nebracetam on neurotransmitters in brain regions after microsphere embolism in rats

    Takeo, Satoshi; Hayashi, Hideki; Miyake, Keiko; Takagi, Kaori; Tadokoro, Mina; Takagi, Norio; Oshikawa, Sayuri

    1997-01-01

    The effects of delayed treatment with nebracetam, a novel nootropic drug, on neurotransmitters of brain regions were examined in rats with microsphere embolism-induced cerebral ischaemia.Cerebral ischaemia was induced by administration of 900 microspheres (48 μm) into the internal carotid artery. The rats with stroke-like symptoms were treated p.o. with 30 mg kg−1 nebracetam twice daily. The levels of acetylcholine, dopamine, noradrenaline, 5-hydroxytryptamine (5-HT) and their metabolites in ...

  2. STUDY OF INJECTION TRAMADOL AS ADDITIVE IN INTRAVENOUS REGIONAL ANESTHESIA

    Rajesh; Sandeep,; Vishal V; Preeti V; Harshad

    2015-01-01

    Now a days IVRA is developed with use of double tourniquet and additive drugs like opioids, NSAIDS , muscle relaxants etc ., to minimize the intraoperative discomfort of surgery and tourniquet pain. Many additives can take care of the post - operative pain. Each additive has its own pros and cons. Tramadol is a synthetic opioid analgesic having additional local anesthetic propert y and effect in neurotransmitter reuptake. With this background we studied the in...

  3. Additions to the flora of Marathwada region of Maharashtra, India

    S.P. Gaikwad

    2012-04-01

    Full Text Available The present communication reports thirteen taxa of flowering plants not previously recorded from Marathwada region. A brief taxonomic description along with phenological and GPS data, distribution, and habitat are provided for each taxon.

  4. Effects of time delay on stochastic resonance of a periodically driven linear system with multiplicative and periodically modulated additive white noises

    Stochastic resonance (SR) of a periodically driven time-delayed linear system with multiplicative white noise and periodically modulated additive white noise is investigated. In the condition of small delay time, an approximate analytical expression of output signal-to-noise ratio (SNR) is obtained. The analytical results indicate that (1) there exists a resonance peak in the curve for SNR versus time delay; (2) the time delay will suspend the SR dramatically for SNR versus other parameters of the system, such as noise intensity, correlation intensity, and signal frequency, once a certain value is reached, the SR phenomenon disappears. (general)

  5. Delayed Proton Emission in the A=70 Region, a Strobe for Level Density and Particle Width

    2002-01-01

    The delayed particle emission, which is a characteristic signature of the most exotic nuclei decay, provides a wide variety of spectroscopic information among which level density, and gives in some cases access to selected microscopic structures. In regard to these two aspects the $\\beta^+$-EC delayed proton emission in the A=70 neutron deficient mass region is of special interest to be investigated. Indeed, in this area located close to the proton drip line and along the N=Z line, the delayed proton emission constitutes an access to level density in the Q$_{EC}$-S$_p$ window of the emitting nucleus. Moreover, the unbound states populated by the EC process are expected to exhibit lifetimes in the vicinity of the K electronic shell filling time ($\\tau\\!\\sim\\!2\\times10^{-16}$s) and so the particle widths can be reached via proton X-ray coincidence measurements (PXCT). From theoretical approaches strongly deformed low-spin proton unbound levels which may be populated in the T$_Z$ = 1/2 precursors decay are predi...

  6. Increased risk of schizophrenia from additive interaction between infant motor developmental delay and obstetric complications: evidence from a population-based longitudinal study.

    Clarke, Mary C

    2011-12-01

    Obstetric complications and developmental delay are well-established risk factors for schizophrenia. The authors investigated whether these risk factors interact in an additive manner to further increase risk for schizophrenia.

  7. Reactive changes in astrocytes, and delayed neuronal death, in the rat hippocampal CA1 region following cerebral ischemia/reperfusion

    Guiqing Zhang; Xiang Luo; Zhiyuan Yu; Chao Ma; Shabei Xu; Wei Wang

    2009-01-01

    BACKGROUND: Blood supply to the hippocampus is not provided by the middle cerebral artery. However, previous studies have shown that delayed neuronal death in the hippocampus may occur following focal cerebral ischemia induced by middle cerebral artery occlusion. OBJECTIVE: To observe the relationship between reactive changes in hippocampal astrocytes and delayed neuronal death in the hippocampal CA1 region following middle cerebral artery occlusion. DESIGN, TIME AND SETTING: The immunohistochemical, randomized, controlled animal study was performed at the Laboratory of Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, from July to November 2007. MATERIALS: Rabbit anti-glial fibrillary acidic protein (GFAP) (Neomarkers, USA), goat anti-rabbit IgG (Sigma, USA) and ApoAlert apoptosis detection kit (Biosciences Clontech, USA) were used in this study. METHODS: A total of 42 healthy adult male Wistar rats, aged 3-5 months, were randomly divided into a sham operation group (n = 6) and a cerebral ischemia/reperfusion group (n = 36). In the cerebral ischemia/reperfusion group, cerebral ischemia/reperfusion models were created by middle cerebral artery occlusion. In the sham operation group, the thread was only inserted into the initial region of the internal carotid artery, and middle cerebral artery occlusion was not induced. Rats in the cerebral ischemia/reperfusion group were assigned to a delayed neuronal death (+) subgroup and a delayed neuronal death (-) subgroup, according to the occurrence of delayed neuronal death in the ischemic side of the hippocampal CA1 region following cerebral ischemia. MAIN OUTCOME MEASURES: Delayed neuronal death in the hippocampal CA1 region was measured by Nissl staining. GFAP expression and delayed neuronal death changes were measured in the rat hippocampal CA1 region at the ischemic hemisphere by double staining for GFAP and TUNEL. RESULTS: After 3 days of ischemia

  8. $\\beta$-delayed fission in proton-rich nuclei in the lead region

    AUTHOR|(CDS)2085005; Huyse, Mark; Popescu, Lucia

    Nuclear fission is the breakup of an atomic nucleus into two (sometimes three) fragments, thereby releasing a large amount of energy. Soon after its discovery in the late 1930’s, the gross properties of the fission phenomenon were explained by macroscopic nuclear models. Certain features however, such as asymmetric fission-fragment mass distributions in the actinide region, require the inclusion of microscopic effects. This interplay of the microscopic motion of individual nucleons on this macroscopic process is, until today, not yet fully understood. The phenomenon of fission has therefore been of recurring interest for both theoretical and experimental studies. This thesis work focuses on the $\\beta$-delayed fission ($\\beta$DF) process, an excellent tool to study low-energy fission of exotic nuclei, which was discovered in 1966 in the actinide region. In this two-step process, a precursor nucleus first undergoes $\\beta$-decay to an excited level in the daughter nucleus, which may subsequently fission. Rec...

  9. Regional variations in early intervention utilization for children with developmental delay.

    Grant, Roy; Isakson, Elizabeth A

    2013-09-01

    We tested whether state-level variations in early intervention program (EI) participation were consistent with rates of key risk factors for early developmental delay. Based on the results of prior studies, we focused on child poverty and low birth weight as risk factors, included state threshold for EI eligibility by category (classified as broad/moderate or narrow), and aggregated the states into regions. Bivariate analyses were done in SPSS 15.0. All data were for 2009. Results were tested against data for prior years to ascertain whether findings for 2009 were anomalous. Nationally, 2.67 % of the age-eligible population was served in EI (range among states, 1.24-6.51 %). Variation in EI participation was significant at the regional level. Early intervention participation was lowest in the south and highest in the northeast (p child poverty (p < 0.01) were also significant. Both were highest in the south. While EI participation varied significantly by state eligibility standards, this factor did not entirely explain variance in utilization. Results for 2009 were representative of multi-year trend data. National EI utilization rates consistently lagged behind need as identified in epidemiologic studies from multiple sources. The results strongly suggest that there is a significant population of infants and toddlers who need but do not receive EI services, especially in the south. PMID:22918713

  10. The Degrees of Freedom Regions of Two-User and Certain Three-User MIMO Broadcast Channels with Delayed CSIT

    Vaze, Chinmay S.; Varanasi, Mahesh K.

    2010-01-01

    The degrees of freedom (DoF) region of the fast-fading MIMO (multiple-input multiple-output) Gaussian broadcast channel (BC) is studied when there is delayed channel state information at the transmitter (CSIT). In this setting, the channel matrices are assumed to vary independently across time and the transmitter is assumed to know the channel matrices with some arbitrary finite delay. An outer-bound to the DoF region of the general $K$-user MIMO BC (with an arbitrary number of antennas at ea...

  11. Combined action of time-delay and colored cross-associated multiplicative and additive noises on stability and stochastic resonance for a stochastic metapopulation system

    Wang, Kang-Kang; Zong, De-Cai; Wang, Ya-Jun; Li, Sheng-Hong

    2016-05-01

    In this paper, the transition between the stable state of a big density and the extinction state and stochastic resonance (SR) for a time-delayed metapopulation system disturbed by colored cross-correlated noises are investigated. By applying the fast descent method, the small time-delay approximation and McNamara and Wiesenfeld's SR theory, we investigate the impacts of time-delay, the multiplicative, additive noises and colored cross-correlated noise on the SNR and the shift between the two states of the system. Numerical results show that the multiplicative, additive noises and time-delay can all speed up the transition from the stable state to the extinction state, while the correlation noise and its correlation time can slow down the extinction process of the population system. With respect to SNR, the multiplicative noise always weakens the SR effect, while noise correlation time plays a dual role in motivating the SR phenomenon. Meanwhile, time-delay mainly plays a negative role in stimulating the SR phenomenon. Conversely, it could motivate the SR effect to increase the strength of the cross-correlation noise in the SNR-β plot, while the increase of additive noise intensity will firstly excite SR, and then suppress the SR effect.

  12. Teleseismic P-wave Delay Time Tomography of the southern Superior Province and Midcontinent Rift System (MRS) Region

    Bollmann, T. A.; van der Lee, S.; Frederiksen, A. W.; Wolin, E.; Aleqabi, G. I.; Revenaugh, J.; Wiens, D. A.; Darbyshire, F. A.

    2014-12-01

    The Superior Province Rifting Earthscope Experiment (SPREE) and the northern midwest footprint of USArray's Transportable Array recorded continuous ground motion for a period of 2.5 years. From around 400 M>5.5 teleseismic earthquakes recorded at 337 stations, we measured body wave delay times for 255 of these earthquakes. The P wave delays are accumulated over more than 45 thousand wave paths with turning points in the lower mantle. We combine these delay times with a similar number delay times used in previous tomographic studies of the study region. The latter delay times stem from fewer stations, including Polaris and CNSN stations, and nearly a thousand earthquakes. We combine these two sets of delay times to image the three-dimensional distribution of seismic velocity variations beneath the southern Superior Province and surrounding provinces. This combined data coverage is illustrated in the accompanying figure for a total number of 447 stations . The coverage and the combined delays form the best configuration yet to image the three-dimensional distribution of seismic P and S-wave velocity variations beneath the southern Superior and surrounding provinces. Closely spaced stations (~12 km) along and across the MRS provide higher resolving power for lithospheric structure beneath the rift system. Conforming to expectations that the entire region is underlain by thick, cool lithosphere, a mean delay of -.55 +/- .54 s. This is very similar to the mean delays -.6s +/- .37s measured for this region before 2012. Event corrections range from -.2 +/-.54 s and correlate with tectonics for 80% of the earthquakes. An inversion of these nearly one hundred thousand P and around thirty thousand S-wave delay times for high-resolution P and S-wave velocity structure, respectively, does not show structures that are obviously related to the crustal signature of the MRS. None of structures imaged, align with or have a similar shape to the high Mid-continent Gravity Anomaly

  13. Study on the Effective Region of Active Decoy Jamming to SAR Based on Time-delay Doppler-shift Method

    Liu Yong-cai

    2013-03-01

    Full Text Available The active decoy jamming to SAR based on the Time-Delay Doppler-Shift (TDDS method takes effect in certain region. Proper utilization of jamming ensuring decoy quality is based on the study of the effective region. After the mathematical analysis of the difference between jamming signal and real point-target echo, the paper points out that residual RCM, matched filter error, loss of doppler bandwidth are three main factors deteriorating the focus of jamming signal. Formulation of effective region is obtained and verified by simulation results. The study indicates that the TDDS method can effectively protect limited region around the jammer.

  14. The plasmacytoma resistance gene, Pctr2, delays the onset of tumorigenesis and resides in the telomeric region of chromosome 4.

    Mock, B A; Hartley, J; Le Tissier, P; Wax, J S; Potter, M

    1997-11-15

    Mouse plasmacytomas share pathogenetic features in common with both multiple myeloma and Burkitt's lymphoma in humans. Susceptibility to plasmacytoma induction by intraperitoneal pristane in mice is controlled by multiple genes. At least two of these genes reside on mouse chromosome 4 in regions of the genome sharing linkage homology with human chromosomes 9p21, 1p32, and 1p36. A series of congenic strains recombinant for regions of mouse chromosome 4 in the vicinity of the Pctr2 predisposition locus were created and typed for their tumor susceptibility/resistance phenotypes. These strains were derived by introgressively backcrossing alleles from resistant DBA/2 mice onto the susceptible BALB/cAnPt background. Six resistant and two susceptible strains were allelotyped for 10 genes and 49 random DNA markers to identify the smallest region of overlap in the resistant strains. These studies have determined that the Pctr2 locus resides in either a 500-kb interval proximal to Nppa, or in a 1- to 2-centiMorgan (cM) interval distal to Nppa. In these congenic strain analyses, the Nppa and Fv1 loci, in addition to genes within about 1 cM of these loci, have been excluded as candidates for the Pctr2 locus. A relevant locus that may reside in this interval is Rep2; it is associated with the efficiency of repairing X-ray induced DNA damage sustained during the G2 phase of the mitotic cycle. The Pctr2 locus acts in a codominant fashion. F1 hybrids between resistant and susceptible congenic strains exhibit a reduced tumor incidence and a significant delay in the onset of tumorigenesis. Identification and eventual cloning of the Pctr2 locus may assist in the identification of genes involved in many types of cancer showing aberrations in human chromosome 1p36. PMID:9354679

  15. Vascular Steal Explains Early Paradoxical Blood Oxygen Level-Dependent Cerebrovascular Response in Brain Regions with Delayed Arterial Transit Times

    Julien Poublanc

    2013-04-01

    Full Text Available Introduction: Blood oxygen level-dependent (BOLD magnetic resonance imaging (MRI during manipulation of inhaled carbon dioxide (CO2 can be used to measure cerebrovascular reactivity (CVR and map regions of exhausted cerebrovascular reserve. These regions exhibit a reduced or negative BOLD response to inhaled CO2. In this study, we sought to clarify the mechanism behind the negative BOLD response by investigating its time delay (TD. Dynamic susceptibility contrast (DSC MRI with the injection of a contrast agent was used as the gold standard in order to provide measurement of the blood arrival time to which CVR TD could be compared. We hypothesize that if negative BOLD responses are the result of a steal phenomenon, they should be synchronized with positive BOLD responses from healthy brain tissue, even though the blood arrival time would be delayed. Methods: On a 3-tesla MRI system, BOLD CVR and DSC images were collected in a group of 19 patients with steno-occlusive cerebrovascular disease. For each patient, we generated a CVR magnitude map by regressing the BOLD signal with the end-tidal partial pressure of CO2 (PETCO2, and a CVR TD map by extracting the time of maximum cross-correlation between the BOLD signal and PETCO2. In addition, a blood arrival time map was generated by fitting the DSC signal with a gamma variate function. ROI masks corresponding to varying degrees of reactivity were constructed. Within these masks, the mean CVR magnitude, CVR TD and DSC blood arrival time were extracted and averaged over the 19 patients. CVR magnitude and CVR TD were then plotted against DSC blood arrival time. Results: The results show that CVR magnitude is highly correlated to DSC blood arrival time. As expected, the most compromised tissues with the longest blood arrival time have the lowest (most negative CVR magnitude. However, CVR TD shows a noncontinuous relationship with DSC blood arrival time. CVR TD is well correlated to DSC blood arrival time

  16. Influence of Mineral Additions in the Inhibition of Delayed Ettringite Formation in Cement based Materials – A Microstructural Characterization

    Santos Silva, A.; Soares, D.; L. Matos; Salta, M.; Divet, Loïc; Pavoine, Alexandre; Candeias, A; Mirao, J.

    2010-01-01

    The degradation of concrete structures caused by delayed ettringite formation (DEF) is aproblem that affects many concrete structures worldwide [1]. This pathology is due to the formation of expansive ettringite inside the material and is very difficult to deal with, because presently there is no efficient method to repair concrete structures affected by DEF. Hence, there is an urgent need to find preventive methods that may enable the inhibition of DEF in new constructions. This paper presen...

  17. Influence of mineral additions in the inhibition of delayed ettringite formation in cement based materials. A microstructural characterization

    Divet, Loïc; SANTOS SILVA, Antonio; Soares, D.; L. Matos; Salta, M.; Pavoine, Alexandre; Candeias, A; Mirao, J.

    2009-01-01

    The degradation of concrete structures caused by delayed ettringite formation (DEF) is a problem that affects many concrete structures worldwide [1]. This pathology is due to the formation of expansive ettringite inside the material and is very difficult to deal with, because presently there is no efficient method to repair concrete structures affected by DEF. Hence, there is an urgent need to find preventive methods that may enable the inhibition of DEF in new constructions. This paper prese...

  18. Delayed onset of tricuspid valve flow in repaired tetralogy of Fallot: an additional mechanism of diastolic dysfunction and interventricular dyssynchrony

    Benson Lee N; Redington Andrew N; Bronzetti Gabriele; Cheung Michael; AlHabshan Fahad; Sun Ai-Min; Macgowan Christopher; Yoo Shi-Joon

    2011-01-01

    Abstract Background Diastolic dysfunction of the right ventricle (RV) is common after repair of tetralogy of Fallot. While restrictive physiology in late diastole has been well known, dysfunction in early diastole has not been described. The present study sought to assess the prevalence and mechanism of early diastolic dysfunction of the RV defined as delayed onset of the tricuspid valve (TV) flow after TOF repair. Methods The study population consisted of 31 children with repaired TOF (mean ...

  19. Factors influencing surgical delay after hip fracture in hospitals of Emilia Romagna Region, Italy: a multilevel analysis.

    Belotti, Laura Maria Beatrice; Bartoli, Simona; Trombetti, Susanna; Montella, Maria Teresa; Toni, Aldo; De Palma, Rossana

    2013-01-01

    Hip fracture is becoming a major public health concern, with associated mortality and morbidity particularly in the elderly. This study aims to investigate factors (i.e. patient factors and hospital variables) associated with increased risk for delaying surgery after hip fractures, and to assess whether and to what extent timing was associated with mortality risk. All patients aged 65 and over, resident in Emilia Romagna Region (Italy) and admitted to hospital for hip fracture (2009 - 2010) were selected. Data on surgical delay were adjusted using multilevel logistic regression model. A Cox proportional hazard model was fitted to a propensity score matched sample to assess mortality between delayed and early treated patients. Of the 10, 995 patients included (mean age: 83.3 years), 44.9% underwent surgery within 2 days. Significant risk factors for delayed surgery were: gender (OR: 1.16), comorbidity (OR: 1.29), anticoagulant (OR: 7.64) ,antiplatelet medication (OR: 2.43) , type of procedure (OR: 1.37) and day of admission (OR: Thu-Fri: 6.05; Sat-Sun: 1.17). Type of hospital and annual volume of hip fracture surgeries were not sufficient to explain hospital variability. A significant difference in mortality rate between early and delayed surgery emerged six months post surgery. PMID:23397198

  20. Pubertal hormones modulate the addition of new cells to sexually dimorphic brain regions

    Ahmed, Eman I.; Zehr, Julia L.; Schulz, Kalynn M.; Lorenz, Betty H.; Doncarlos, Lydia L.; Sisk, Cheryl L.

    2008-01-01

    New cells, including neurons, arise in several brain regions during puberty in rats. Sex differences in pubertal addition of cells coincide with adult sexual dimorphisms: for each region, the sex that gains more cells during puberty has a larger volume in adulthood. Removing gonadal hormones before puberty eliminates these sex differences, indicating that gonadal steroids direct the addition of new cells during puberty to maintain and accentuate sexual dimorphisms in the adult brain.

  1. The estimation of β-delayed two-neutron emission probability in the A>=50 region

    The probability of recently discovered β-delayed two-neutron emission is calculated using the microscopic model based on the finite Fermi systems theory. For nuclei of sup(50,51,52)K, 86As, 92Br, 91Se, sup(98,99,100)Rb, 132In, 136Sb with measured half-lives predictions are made. The effect of the β-strength function structure on β-delayed two-neutron emission probability in the continuous part of the spectrum is discussed. (orig.)

  2. Regional Brain Differences in the Effect of Distraction During the Delay Interval of a Working Memory Task

    Dolcos, Florin; Miller, Brian; Kragel, Philip; Jha, Amishi; McCarthy, Gregory

    2007-01-01

    Working memory (WM) comprises operations whose coordinated action contributes to our ability to maintain focus on goal-relevant information in the presence of distraction. The present study investigated the nature of distraction upon the neural correlates of WM maintenance operations by presenting task-irrelevant distracters during the interval between the memoranda and probes of a delayed-response WM task. The study used a region of interest (ROIs) approach to investigate the role of anterio...

  3. Addition of ketamine or dexmedetomidine to lignocaine in intravenous regional anesthesia: A randomized controlled study

    Alok Kumar

    2012-01-01

    Results: Shortened sensory and motor block onset times (69.17 min and 7.83 min respectively, P < 0.0001 and improved quality of anesthesia (satisfaction score = 3, P < 0.05 were found in ketamine group. Visual analog scale scores (3.21 ± 0.41 were comparable while time to first analgesic requirement (166.25 ± 25.89 min, P < 0.0001 was significantly longer in dexmedetomidine group after tourniquet release. Conclusion: We conclude that the addition of 1 mcg/kg of body weight dexmedetomidine or 0.5 mg/kg of body weight ketamine to lignocaine for IVRA improves quality of anesthesia and perioperative analgesia without causing side effects. We considered ketamine reduced the time for onset of block, delayed the onset of tourniquet pain, and reduced postoperative analgesic requirement and had a better patient satisfaction than placebo or dexmedetomidine.

  4. A Working Memory Buffer in Parahippocampal Regions: Evidence from a Load Effect during the Delay Period.

    Schon, Karin; Newmark, Randall E; Ross, Robert S; Stern, Chantal E

    2016-05-01

    Computational models have proposed that the entorhinal cortex (EC) is well suited for maintaining multiple items in working memory (WM). Evidence from animal recording and human neuroimaging studies show that medial temporal lobe areas including the perirhinal (PrC), EC, and CA1 hippocampal subfield may contribute to active maintenance during WM. Previous neuroimaging work also suggests CA1 may be recruited transiently when encoding novel information, and EC and CA1 may be involved in maintaining multiple items in WM. In this study, we tested the prediction that a putative WM buffer would demonstrate a load-dependent effect during a WM delay. Using high-resolution fMRI, we examined whether activity within the hippocampus (CA3/DG, CA1, and subiculum) and surrounding medial temporal cortices (PrC, EC, and parahippocampal cortex-PHC) is modulated in a load-dependent manner. We employed a delayed matching-to-sample task with novel scenes at 2 different WM loads. A contrast between high- and low-WM load showed greater activity within CA1 and subiculum during the encoding phase, and greater EC, PrC, and PHC activity during WM maintenance. These results are consistent with computational models and suggest that EC/PrC and PHC act as a WM buffer by actively maintaining novel information in a capacity-dependent manner. PMID:25662713

  5. Immediate and delayed micro-tensile bond strength of different luting resin cements to different regional dentin

    Ali, Abdelraheem Mohamed; Hamouda, Ibrahim Mohamed; Ghazy, Mohamed Hamed; Abo-Madina, Manal Mohamed

    2012-01-01

    We sought to evaluate immediate and delayed micro-tensile bond strength of Panavia F2.0 and Multilink Sprint resin cement to superficial, deep and cervical dentin. Thirty-six freshly extracted non-carious human molars were sectioned in the mesiodistal direction to expose three different dentin regions including superficial dentin (1 mm below the dentine-enamel junction), deep dentin (1 mm above the highest pulp horn) and cervical dentin (0.5 mm above the cemento-enamel junction and 0.5 mm bel...

  6. Organic Matter and Water Addition Enhance Soil Respiration in an Arid Region

    Liming Lai; Jianjian Wang; Yuan Tian; Xuechun Zhao; Lianhe Jiang; Xi Chen; Yong Gao; Shaoming Wang; Yuanrun Zheng

    2013-01-01

    Climate change is generally predicted to increase net primary production, which could lead to additional C input to soil. In arid central Asia, precipitation has increased and is predicted to increase further. To assess the combined effects of these changes on soil CO2 efflux in arid land, a two factorial manipulation experiment in the shrubland of an arid region in northwest China was conducted. The experiment used a nested design with fresh organic matter and water as the two controlled par...

  7. Fine-mapping in the MHC region accounts for 18% additional genetic risk for celiac disease

    Gutierrez-Achury, Javier; Zhernakova, Alexandra; Pulit, Sara L.; Trynka, Gosia; Hunt, Karen A.; Romanos, Jihane; Raychaudhuri, Soumya; van Heel, David A.; Wijmenga, Cisca; de Bakker, Paul I.W.

    2015-01-01

    Although dietary gluten is the trigger, celiac disease risk is strongly influenced by genetic variation in the major histocompatibility complex (MHC) region. We fine-mapped the MHC association signal to identify additional risk factors independent of the HLA-DQ alleles and observed five novel associations that account for 18% of the genetic risk. Together with the 57 known non-MHC loci, genetic variation can now explain up to 48% of celiac disease heritability. PMID:25894500

  8. Fine-mapping in the MHC region accounts for 18% additional genetic risk for celiac disease

    Gutierrez-Achury, Javier; Zhernakova, Alexandra; Pulit, Sara L.; Trynka, Gosia; Hunt, Karen A.; Romanos, Jihane; Raychaudhuri, Soumya; Van Heel, David A.; Wijmenga, Cisca; Paul I W de Bakker

    2015-01-01

    Although dietary gluten is the trigger, celiac disease risk is strongly influenced by genetic variation in the major histocompatibility complex (MHC) region. We fine-mapped the MHC association signal to identify additional risk factors independent of the HLA-DQ alleles and observed five novel associations that account for 18% of the genetic risk. Together with the 57 known non-MHC loci, genetic variation can now explain up to 48% of celiac disease heritability.

  9. Isotope investigation of groundwater recharge by delay action dams in the arid region of Balochistan, Pakistan

    Isotope techniques (2H, 18O, 3H) were applied to investigate effectiveness of delay action dam reservoirs in Ziarat Valley of Balochistan. These reservoirs are meant to collect water in rainy seasons and supplement discharge of downstream karezes (subsurface water channels emerging on the ground surface after receiving groundwater through open wells) in dry season by recharging groundwater. The data indicate that the mean values of δ2H, δ18O and tritium of precipitation are: -6.4 per mille, -37 per mille and 9 TU respectively. Ranges of δ18O and δ2H values of the groundwater samples (wells, karezes, springs) are -6.6 to -2.2 per mille and -40 to -16 per mille respectively. The reservoirs have ranges of δ2H and δ18O values from -6.7 to +15.6 per mille and -42 to +86 per mille respectively and they follow evaporation lines on the δ18O-δ2H plots. Isotope data indicate that there is no significant groundwater recharge from the Pechi Dam and Manna Dam reservoirs. Vouch Ghouski Dam has some contribution in groundwater recharge while Warchoom Dam reservoir is much effective in contributing to groundwater recharge. Results of tritium suggest that the residence time of groundwater is quite short (fresh water). (author)

  10. Constraints on the broad line region from regularized linear inversion: Velocity-delay maps for five nearby active galactic nuclei

    Skielboe, Andreas; Treu, Tommaso; Park, Daeseong; Barth, Aaron J; Bentz, Misty C

    2015-01-01

    Reverberation mapping probes the structure of the broad emission-line region (BLR) in active galactic nuclei (AGN). The radius of the BLR along with the virial velocity of the BLR gas can be used to measure the mass of the supermassive black hole. The main systematic uncertainty affecting reverberation mapping is the unknown structure of the BLR. We develop a new method for analysing reverberation mapping data based on regularized linear inversion (RLI) that includes statistical modelling of the AGN continuum light curves. This method enables fast, flexible, and robust calculation of velocity-resolved response maps to probe BLR structure. Contrary to other methods, RLI allows for negative response in the BLR, such as when some areas of the BLR respond in inverse proportion to a change in ionizing continuum luminosity. We present time delays, integrated response functions, and velocity-delay maps for the H{\\beta} broad emission line in five nearby AGN, as well as H{\\alpha} and H{\\gamma} broad emission lines in...

  11. Organic matter and water addition enhance soil respiration in an arid region.

    Liming Lai

    Full Text Available Climate change is generally predicted to increase net primary production, which could lead to additional C input to soil. In arid central Asia, precipitation has increased and is predicted to increase further. To assess the combined effects of these changes on soil CO2 efflux in arid land, a two factorial manipulation experiment in the shrubland of an arid region in northwest China was conducted. The experiment used a nested design with fresh organic matter and water as the two controlled parameters. It was found that both fresh organic matter and water enhanced soil respiration, and there was a synergistic effect of these two treatments on soil respiration increase. Water addition not only enhanced soil C emission, but also regulated soil C sequestration by fresh organic matter addition. The results indicated that the soil CO2 flux of the shrubland is likely to increase with climate change, and precipitation played a dominant role in regulating soil C balance in the shrubland of an arid region.

  12. Delayed X-Ray Afterglows from Obscured Gamma-Ray Bursts in Star-Forming Regions

    Meszaros, P.; Gruzinov, A.

    2000-01-01

    For Gamma-Ray Bursts occurring in dense star-forming regions, the X-ray afterglow behavior minutes to days after the trigger may be dominated by the small-angle scattering of the prompt X-ray emission off dust grains. We give a simple illustrative model for the X-ray light curves at different X-ray energies, and discuss possible implications. A bump followed by a steeper decay in soft X-rays is predicted for bursts which are heavily obscured in the optical.

  13. Transferability of regional permafrost disturbance susceptibility modelling using generalized linear and generalized additive models

    Rudy, Ashley C. A.; Lamoureux, Scott F.; Treitz, Paul; van Ewijk, Karin Y.

    2016-07-01

    To effectively assess and mitigate risk of permafrost disturbance, disturbance-prone areas can be predicted through the application of susceptibility models. In this study we developed regional susceptibility models for permafrost disturbances using a field disturbance inventory to test the transferability of the model to a broader region in the Canadian High Arctic. Resulting maps of susceptibility were then used to explore the effect of terrain variables on the occurrence of disturbances within this region. To account for a large range of landscape characteristics, the model was calibrated using two locations: Sabine Peninsula, Melville Island, NU, and Fosheim Peninsula, Ellesmere Island, NU. Spatial patterns of disturbance were predicted with a generalized linear model (GLM) and generalized additive model (GAM), each calibrated using disturbed and randomized undisturbed locations from both locations and GIS-derived terrain predictor variables including slope, potential incoming solar radiation, wetness index, topographic position index, elevation, and distance to water. Each model was validated for the Sabine and Fosheim Peninsulas using independent data sets while the transferability of the model to an independent site was assessed at Cape Bounty, Melville Island, NU. The regional GLM and GAM validated well for both calibration sites (Sabine and Fosheim) with the area under the receiver operating curves (AUROC) > 0.79. Both models were applied directly to Cape Bounty without calibration and validated equally with AUROC's of 0.76; however, each model predicted disturbed and undisturbed samples differently. Additionally, the sensitivity of the transferred model was assessed using data sets with different sample sizes. Results indicated that models based on larger sample sizes transferred more consistently and captured the variability within the terrain attributes in the respective study areas. Terrain attributes associated with the initiation of disturbances were

  14. Additive angular dependent rebalance acceleration arithmetic for neutron transport equation in optically thick diffusive region

    The first-order neutron transport equation was solved by the least-squares finite element method based on the discrete ordinates discretization. For the traditional source iteration method is very slowly for the optically thick diffusive medium, sometime even divergent especially for the scattering ratio is close to unity, so the acceleration method should be proposed. There is only diffusive synthetical acceleration (DSA) for the discontinuous finite element method (DFEM) and almost no one for the least- squares finite element method. The additive angular dependent rebalance (AADR) acceleration arithmetic and its extrapolate method were given, in which the additive modification was used. It was applied to solve the transport equation with fixed source, fission source, in optically thick diffusive regions and with unstructured-mesh. The numerical results of benchmark problems demonstrate that the arithmetic can shorten the CPU time about 1.5-2 times and give high precise. (authors)

  15. Delayed neutron and delayed photon characteristics from photofission of 232Th, 235,238U, and 237Np with endpoint Bremsstrahlung photons in the giant dipole resonance region

    A renewed interest in photonuclear reactions was stimulated by applications as radioactive ion beam production, irradiation stations by high energy photons, shielding of electron accelerators, etc. Today, a particular attention is paid to the non-destructive characterization of waste barrels and the detection of nuclear materials, both based on photofission process and the associated delayed neutron (DN) and delayed photon (DP) emissions. The need of accurate and complete data for DN and DP yields and time characteristics of actinides was the motivation for an experimental campaign, started in 2004. In this paper, the experimental setup and the data analysis method will be presented and the modeling work will be described. Experimental results for DN and DP characteristics will be compared to calculations in the case of photofission of 232Th, 235,238U, and 237Np. (authors)

  16. Delayed neutron and delayed photon characteristics from photofission of 232Th, 235,238U, and 237Np with endpoint Bremsstrahlung photons in the giant dipole resonance region

    Doré, D.; Dighe, P. M.; Berthoumieux, E.; Laborie, J.-M.; Ledoux, X.; Macary, V.; Panebianco, S.; Ridikas, D.

    2009-10-01

    A renewed interest in photonuclear reactions was stimulated by applications as radioactive ion beam production, irradiation stations by high energy photons, shielding of electron accelerators, etc. Today, a particular attention is paid to the non-destructive characterization of waste barrels and the detection of nuclear materials, both based on photofission process and the associated delayed neutron (DN) and delayed photon (DP) emissions. The need of accurate and complete data for DN and DP yields and time characteristics of actinides was the motivation for an experimental campaign, started in 2004. In this paper, the experimental setup and the data analysis method will be presented and the modeling work will be described. Experimental results for DN and DP characteristics will be compared to calculations in the case of photofission of 232Th, 235,238U, and 237Np.

  17. Variability of wet troposphere delays over inland reservoirs as simulated by a high-resolution regional climate model

    Clark, E.; Lettenmaier, D. P.

    2014-12-01

    Satellite radar altimetry is widely used for measuring global sea level variations and, increasingly, water height variations of inland water bodies. Existing satellite radar altimeters measure water surfaces directly below the spacecraft (approximately at nadir). Over the ocean, most of these satellites use radiometry to measure the delay of radar signals caused by water vapor in the atmosphere (also known as the wet troposphere delay (WTD)). However, radiometry can only be used to estimate this delay over the largest inland water bodies, such as the Great Lakes, due to spatial resolution issues. As a result, atmospheric models are typically used to simulate and correct for the WTD at the time of observations. The resolutions of these models are quite coarse, at best about 5000 km2 at 30˚N. The upcoming NASA- and CNES-led Surface Water and Ocean Topography (SWOT) mission, on the other hand, will use interferometric synthetic aperture radar (InSAR) techniques to measure a 120-km-wide swath of the Earth's surface. SWOT is expected to make useful measurements of water surface elevation and extent (and storage change) for inland water bodies at spatial scales as small as 250 m, which is much smaller than current altimetry targets and several orders of magnitude smaller than the models used for wet troposphere corrections. Here, we calculate WTD from very high-resolution (4/3-km to 4-km) simulations of the Weather Research and Forecasting (WRF) regional climate model, and use the results to evaluate spatial variations in WTD. We focus on six U.S. reservoirs: Lake Elwell (MT), Lake Pend Oreille (ID), Upper Klamath Lake (OR), Elephant Butte (NM), Ray Hubbard (TX), and Sam Rayburn (TX). The reservoirs vary in climate, shape, use, and size. Because evaporation from open water impacts local water vapor content, we compare time series of WTD over land and water in the vicinity of each reservoir. To account for resolution effects, we examine the difference in WRF

  18. Inner Mongolia Autonomous Region (IMAR) energy base: Additional final report and recommendations

    Clark, Woodrow W. II.; Isherwood, William [Clark Strategic Partners, PO Box 17975, Beverly Hills, CA 90210 (United States)

    2010-03-15

    The ADB authors felt that an additional set of recommendations were needed to the final Report. Two reasons guided that decision: one was simply that the planned and budgeted final presentation of the Report was to be made in December 07 in Beijing to high level members of the Central Government. That meeting was cancelled. No reason was given but due to the upcoming Olympic Games in August 2008, perhaps discussion of the energy issues in China were too sensitive. But the other reason for the need to state additional recommendations was basically to help support the IMAR government in its direction for the future. The IMAR Government throughout the two years of research for this Report were extremely supportive and actively following the presentations and data. It was obvious that they felt that the Report or parts of it, for example, helping the next Five Year Plan for all of China define what sustainable development was and was not. However there were other elements that emerged including strong support for new alternative energy business development, education in this area, and strong resistance to the IMAR becoming a pipeline for natural gas coming from Russia to China. In short IMAR and China did not want to become another dependent region on Russian fossil fuels. These issues and recommendations are built upon the ADB Report but did not become apart of it. (author)

  19. The structure of the broad-line region in active galactic nuclei. I. Reconstructed velocity-delay maps

    Grier, C.J.; Peterson, B.M.; Pogge, R.W.;

    2013-01-01

    of the most clearly defined velocity-delay maps to date. These maps constitute a large increase in the number of objects for which we have resolved velocity-delay maps and provide evidence supporting the reliability of reverberation-based black hole mass measurements. © 2013. The American......We present velocity-resolved reverberation results for five active galactic nuclei. We recovered velocity-delay maps using the maximum entropy method for four objects: Mrk 335, Mrk 1501, 3C 120, and PG 2130+099. For the fifth, Mrk 6, we were only able to measure mean time delays in different...

  20. Tomography with P, PP and pP delay-time data and the three-dimensional mantle structure below the Caribbean region

    van der Hilst, R.D.

    1990-01-01

    I address in this thesis two principal topics. Firstly, in chapters 2 and 3 I discuss improvements on the method of P delay-time tomography which were necessary to obtain reliable tomographic images of the mantle structure below the Caribbean region. These improvements include the reduction of refer

  1. Serotonin Transporter Promoter Region (5-HTTLPR) Polymorphism Is Not Associated With Paroxetine-Induced Ejaculation Delay in Dutch Men With Lifelong Premature Ejaculation

    Janssen, Paddy K C; Zwinderman, Aeilko H; Olivier, Berend; Waldinger, Marcel D

    2014-01-01

    PURPOSE: To investigate the association between the 5-HT-transporter-gene-linked promoter region (5-HTTLPR) polymorphism and 20-mg paroxetine-induced ejaculation delay in men with lifelong premature ejaculation (LPE). MATERIALS AND METHODS: This was a prospective study of 10 weeks of paroxetine trea

  2. Morphology of temporal region skin in women of different age categories with an additional pathology

    Makarchuk O.I.

    2010-01-01

    Full Text Available To define structural and functional changes of skin in women of different age groups with an additional internal pathology in this work intraoperative biopsy material of skin of 104 women at the age from 19 to 73 years, that was taken during standard surgery instrumentations for different defects of face skin correction, was investigated. Skin material of temporal region was morphologically processed. To define parameters of microvessels, serial sections was investigated with the help of morphometry. It was determined, that involution dynamic of microvessel condition in papillary layer of derma coincides with grade reduction of relative volume of microvessels bed. There is growth of relative microvessels volume in reticular layer of derma in women of older age groups. Microcirculation age changes include structural disorders of intrapapillary capillary loops, disorganization of arterioles in papillary and reticular layers of derma, disorders of venules because of the changes in microenvironmental fibrillar network. It is typical at the patients with nicotinic dependence, ischemic heart disease, hypertonic disease, a diabetes, and also adiposity of a different degree essential infringement of microvessels bed structure of a skin that gives the basis for allocation of the given contingent of patients as group high intraoperative and postoperative risk at carrying out of operative interventions for correction of face skin involutive changes.

  3. Delayed Treatment with Sodium Hydrosulfide Improves Regional Blood Flow and Alleviates Cecal Ligation and Puncture (CLP)-Induced Septic Shock.

    Ahmad, Akbar; Druzhyna, Nadiya; Szabo, Csaba

    2016-08-01

    Cecal ligation and puncture (CLP)-induced sepsis is a serious medical condition, caused by a severe systemic infection resulting in a systemic inflammatory response. Recent studies have suggested the therapeutic potential of donors of hydrogen sulfide (H2S), a novel endogenous gasotransmitter and biological mediator in various diseases. The aim of the present study was to assess the effect of H2S supplementation in sepsis, with special reference to its effect on the modulation of regional blood flow. We infused sodium hydrosulfide (NaHS), a compound that produces H2S in aqueous solution (1, 3, or 10 mg/kg/h, for 1 h at each dose level) in control rats or rats 24 h after CLP, and measured blood flow using fluorescent microspheres. In normal control animals, NaHS induced a characteristic redistribution of blood flow, and reduced cardiac, hepatic, and renal blood flow in a dose-dependent fashion. In contrast, in rats subjected to CLP, cardiac, hepatic, and renal blood flow was significantly reduced; infusion of NaHS (1 mg/kg/h and 3 mg/kg/h) significantly increased organ blood flow. In other words, the effect of H2S on regional blood flow is dependent on the status of the animals (i.e., a decrease in blood flow in normal controls, but an increase in blood flow in CLP). We have also evaluated the effect of delayed treatment with NaHS on organ dysfunction and the inflammatory response by treating the animals with NaHS (3 mg/kg) intraperitoneally (i.p.) at 24 h after the start of the CLP procedure; plasma levels of various cytokines and tissue indicators of inflammatory cell infiltration and oxidative stress were measured 6 h later. After 24 h of CLP, glomerular function was significantly impaired, as evidenced by markedly increased (over 4-fold over baseline) blood urea nitrogen and creatinine levels; this increase was also significantly reduced by treatment with NaHS. NaHS also attenuated the CLP-induced increases in malondialdehyde levels (an index of

  4. Value addition of wild apricot fruits grown in North-West Himalayan regions-a review.

    Sharma, Rakesh; Gupta, Anil; Abrol, G S; Joshi, V K

    2014-11-01

    Wild apricot (Prunus armeniaca L.) commonly known as chulli is a potential fruit widely distributed in North-West Himalayan regions of the world. The fruits are good source of carbohydrates, vitamins, minerals besides having attractive colour and typical flavour. Unlike table purpose varieties of apricots like New Castle, the fruits of wild apricot are unsuitable for fresh consumption because of its high acid and low sugar content. However, the fruits are traditionally utilized for open sun drying, pulping to prepare different products such as jams, chutney and naturally fermented and distilled liquor. But, scientific literature on processing and value addition of wild apricot is scanty. Preparation of jam with 25 % wild apricot +75 % apple showed maximum score for organoleptic characteristics due to better taste and colour. Osmotic dehydration has been found as a suitable method for drying of wild type acidic apricots. A good quality sauce using wild apricot pulp and tomato pulp in the ratio of 1:1 has been prepared, while chutney of good acceptability prepared from wild apricot pulp (100 %) has also been documented. Preparation of apricot-soy protein enriched products like apricot-soya leather, toffee and fruit bars has been reported, which are reported to meet the protein requirements of adult and children as per the recommendations of ICMR. Besides these processed products, preparation of alcoholic beverages like wine, vermouth and brandy from wild apricot fruits has also been reported by various researchers. Further, after utilization of pulp for preparation of value added products, the stones left over have been successfully utilized for oil extraction which has medicinal and cosmetic value. The traditional method of oil extraction has been reported to be unhygienic and result in low oil yield with poor quality, whereas improved mechanical method of oil extraction has been found to produce good quality oil. The apricot kernel oil and press cake have

  5. Studies on the Regional Cerebral Blood Flow in Delayed Carbon Monoxide sequelae using 99mTc-HMPAO

    8 patients of delayed CO sequelae were evaluated using Brain CT and 99mTc-HMPAO SPECT. The results were as follows; 1) CT findings of delayed CO sequelae were bilateral low density lesion in globus pallidus (1 pt.), diffuse low density in white matter with bilateral low density in white matter (1 pt.), diffuse low density in white matter with bilateral low density in globus pallidus (1 pt.), diffuse low density in white matter with cortical atrophy (1 pt.), bilateral low density in globus pallidus and diffuse low density in white matter with cortical atrophy (1 pt.) and normal in 3 pts. 2) 99mTc-HMPAO Brain SPECT findings of delayed CO sequelae were decreased regiona1 cerebral blood flow (rCBF) in frontal (1 among 8 pts.), frontal and basal ganglia (3 among 8 pts.), and diffuse patch decreased rCBF pattern (4 among 8 pts.) 3) 99mTc-HMPAO Brain SPECT study was well correlated with neurologic symptoms and signs in delayed CO sequelae. Our results may suggest that reduced cerebral blood flow contributes to the development of delayed CO sequelae.

  6. Serotonin Transporter Promoter Region (5-HTTLPR) Polymorphism Is Not Associated With Paroxetine-Induced Ejaculation Delay in Dutch Men With Lifelong Premature Ejaculation

    Paddy K C Janssen; Zwinderman, Aeilko H; Olivier, Berend; Waldinger, Marcel D.

    2014-01-01

    PURPOSE: To investigate the association between the 5-HT-transporter-gene-linked promoter region (5-HTTLPR) polymorphism and 20-mg paroxetine-induced ejaculation delay in men with lifelong premature ejaculation (LPE). MATERIALS AND METHODS: This was a prospective study of 10 weeks of paroxetine treatment in 54 men with LPE. Intravaginal ejaculation latency time (IELT) was measured by stopwatch. Controls consisted of 92 Caucasian men. All men with LPE were genotyped for the 5-HTTLPR polymorphi...

  7. Value addition of wild apricot fruits grown in North–West Himalayan regions-a review

    Sharma, Rakesh; Gupta, Anil; Abrol, G. S.; Joshi, V. K.

    2012-01-01

    Wild apricot (Prunus armeniaca L.) commonly known as chulli is a potential fruit widely distributed in North-West Himalayan regions of the world. The fruits are good source of carbohydrates, vitamins, minerals besides having attractive colour and typical flavour. Unlike table purpose varieties of apricots like New Castle, the fruits of wild apricot are unsuitable for fresh consumption because of its high acid and low sugar content. However, the fruits are traditionally utilized for open sun d...

  8. An Analytical Delay Model

    MIN Yinghua; LI Zhongcheng

    1999-01-01

    Delay consideration has been a majorissue in design and test of high performance digital circuits. Theassumption of input signal change occurring only when all internal nodesare stable restricts the increase of clock frequency. It is no longertrue for wave pipelining circuits. However, previous logical delaymodels are based on the assumption. In addition, the stable time of arobust delay test generally depends on the longest sensitizable pathdelay. Thus, a new delay model is desirable. This paper explores thenecessity first. Then, Boolean process to analytically describe thelogical and timing behavior of a digital circuit is reviewed. Theconcept of sensitization is redefined precisely in this paper. Based onthe new concept of sensitization, an analytical delay model isintroduced. As a result, many untestable delay faults under thelogical delay model can be tested if the output waveforms can be sampledat more time points. The longest sensitizable path length is computedfor circuit design and delay test.

  9. The delayed proton emission in the A=65-77 mass region statistical aspects and structure effects

    The β delayed proton emission of the TZ=1/2 precursors 65Ge, 69Se, 73Kr, 77Sr is analysed in terms of statistical behaviour including fluctuation phenomena. Average values of level spacing, partial particle width and total level width are obtained for the proton emitting isotopes. Indications arise for specific structure effects in both the β strength function and the particle emission process. (authors). 11 refs., 2 figs., 1 tab

  10. Retrieval of Wet-Tropospheric Path Delay over Coastal and Inland Water Regions using Wide-band Millimeter-Wave Radiometry

    Bosch-Lluis, Xavier; Gilliam, Kyle L.; Reising, Steven C.; Tanner, Alan B.; Brown, Shannon T.; Kangaslahti, Pekka

    2013-04-01

    Currently, wet-tropospheric path delay measurements over inland water and coastal areas are extremely sparse. They are generally limited to twice-per-day radiosonde launches and a small number of ground-based GPS or radiometer path delay measurements, as well as radar measurements of phase delay to a small number of fixed targets on the ground. Knowledge of the wet-tropospheric path delay is necessary for next-generation high-resolution altimeters, such as the Surface Water and Ocean Topography (SWOT) mission, in formulation and planned for launch in 2020. SWOT has two major science objectives. First, the oceanographic objective is to characterize ocean mesoscale and sub-mesoscale circulation with horizontal resolution of 10 km and order of 1 cm height precision. Second, the hydrological objective is to provide global height measurements of inland surface water bodies with area of greater than 250 square meters and flow rate of rivers with width greater than 100 m. Wet-tropospheric path delay retrieval over coastal and inland-water areas is needed to achieve both of these objectives with sufficient height accuracy. In addition, information on total precipitable water vapor under nearly all weather conditions is needed to improve initialization of numerical weather prediction models. Currently, 18-34 GHz microwave radiometers provide wet-path delay corrections for the Jason series of nadir-viewing altimeters. However, these retrievals are limited to open ocean, and land incursion is unacceptable within 40 km of coastlines. The addition of millimeter-wave radiometers (70-170 GHz) is needed to address this problem by providing smaller surface footprint dimensions proportional to wavelength. In this work, we present a prototype algorithm to demonstrate the potential to retrieve wet-tropospheric path delay from brightness temperatures measured by millimeter-wave radiometers using the Brightness Temperature Deflection Ratio (BTDR) method. The BTDR algorithm retrieves wet

  11. The Revealed Competitiveness of Major Ports in the East Asian Region: An Additive Market Share Analysis

    Tae Seung Kim

    2015-12-01

    Full Text Available In the single cargo market, the ordinary market share analysis method has been the representative tool for revealed competitiveness analysis. This paper develops and employs an applied market share index called the additive market share (AMS. Data are collected from 15 major container ports for the 1998-2013 period. In comparison to the results of an ordinary market share analysis, the highest AMS is observed for the Bohai Rim port cluster from 2008, not for the Yangtze River cluster or the Pearl River cluster. There are substitutable relationships between Yangtze River and non-Chinese ports and between Pearl River and Bohai Rim ports from 2001. Finally, there is an internal competition at Pearl River and Yangtze River ports, whereas Bohai Rim and non-Chinese ports show internally complementary relationships.

  12. Time delay in quantum scattering

    As is well known, the knowledge of the scattering cross section and its angular dependence, as a function of energy, is insufficient to determine the phase shifts uniquely. This led Eisenbud and Wigner to propose the measurement of the scattering lifetime or time delay as an additional independent datum. A rigorous time-dependent study of time delay within the framework of Hilbert space formalism is presented. Specifically, Martin's theory of time delay and the validity of the Eisenbud-Wigner time delay formula are extended to spherically symmetric potentials satisfying the asymptotic fall-off rate V(r) → O(r/sup -2-epsilon/). This extension is obtained by use of a maximal estimate of the rate of convergence of the asymptotic condition and the elimination of Martin's requirement that the scattering operator S be three times differentiable with respect to the free-particle Hamiltonian H0. Also presented are related results on the total time a quantum particle spends inside some bounded regions in position space. It is then proved that any two free particles having identical distributions of energy and angular momentum take exactly identical expectation values for the transit time across an arbitrary spherical region centered at the origin in position space. Ways to extend this result to nonfree Hamiltonians are indicated. Finally, the relationship between the position operator and the Eisenbud-Wigner time delay operator is examined. It is shown that the usual method of calculating time delay based on the classical analysis of the position operator is not exact

  13. Delayed fission

    Delayed fission is a nuclear process that couples beta decay and fission. In the delayed fission process, a parent nucleus undergoes beta decay or electron capture and thus populates excited states in the daughter nucleus. This review covers experimental methods for detecting and measuring delayed fission. Experimental results (ECDF activities and beta-DF activities) and theory are presented. The future prospects for study of delayed fission are discussed. 50 refs., 8 figs., 2 tabs

  14. Impacts of Additional HONO Sources on Concentrations and Deposition of NOy in the Beijing-Tianjin-Hebei Region of China

    Li, Ying; An, Junling; Kajino, Mizuo; Li, Jian; Qu, Yu

    2015-04-01

    Reactive nitrogen-containing compounds (NOy) are involved in many important chemical processes in the atmosphere, including aerosol formation as well as ozone (O3) production and destruction. As NOy deposition was increasing rapidly in China during 1980s ~ 2000s, great effort is urgently needed to reduce N deposition. HONO, an important component of NOy, is a significant precursor of the hydroxyl radical (OH) that drives the formation of O3 and fine particles (PM2.5). Nevertheless, the detailed formation mechanisms of HONO and strength of its sources remain unclear. Unknown HONO sources and their potential impacts on air quality have gained extensive interests but to our current knowledge, the impact of HONO sources on regional-scale deposition of NOy has not been quantified up to date. The goal of this work is to evaluate the effects of the additional HONO sources on concentrations and deposition of individual NOy species as well as the NOy budget in the northern Chinese regions being affected by heavy pollution. Simulations of HONO contributions over Beijing-Tianjin-Hebei region (BTH) during summer and winter periods of 2007 using the fully coupled Weather Research and Forecasting /Chemistry (WRF/Chem) model are performed by including three additional HONO sources: 1) the reaction of photo-excited nitrogen dioxide (NO2*) with water vapor, 2) NO2 heterogeneous reaction at the aerosol surfaces, and 3) HONO emissions. The model results show that the three additional HONO sources produce a 20%~40% (> 100%) increase in monthly-mean OH concentrations in many urban areas in August (February), leading to a 10%~40% (10%~100%) variation in monthly-mean concentrations of NOx, nitrate and PAN, a 5%~10% (10%~40%) increase in the total dry deposition of NOy, and an enhancement of 1.4 Gg N (1.5 Gg N) in the total of dry and wet deposition of NOy over this region in August (February). These results suggest that the additional HONO sources aggravate regional-scale acid deposition

  15. Isotope investigation of interrelation between delay action dams and groundwater in the arid region of Balochistan, Pakistan

    Isotope techniques (2H, 18O, 3H) were applied to investigate interrelationship between delay action dams and groundwater in Ziarat Valley of Balochistan. These reservoirs are meant to collect water in rainy season and supplement groundwater recharge in dry season. The data indicate that the mean values of δ2H, δ18O and tritium of precipitation are: -6.4 per mille, -37 per mille and 9 TU respectively. Ranges of δ18O and δ2H values of the groundwater samples (wells and karezes/kanats) are -6.8 to -4.2 per mille and -42.5 to -0.7 per mille respectively. The δ18O and δ2H of dam reservoirs range from -6.9 to +15.6 per mille and -42.6 to +86 per mille respectively and they follow evaporation lines in the δ18O-δ2H plots. Isotope data indicate that there is no significant groundwater recharge from the Pechi Dam reservoir. Uchki Dam has some contribution in groundwater recharge. Results of tritium suggest that the residence time of groundwater is quite short (fresh water). (author)

  16. Deterministically delayed pseudofractal networks

    On the basis of pseudofractal networks (PFNs), we propose a family of delayed pseudofractal networks (DPFNs) with a special feature that newly added edges delay producing new nodes, differing from the evolution algorithms of PFNs where all existing edges simultaneously generate new nodes. We obtain analytical formulae for degree distribution, clustering coefficient (C) and average path length (APL). We compare DPFNs and PFNs, and show that the exponent of the degree distribution of DPFNs is smaller than that of PFNs, meaning that the heterogeneity of this kind of delayed network is higher. Compared to PFNs, small-world features of DPFNs are more prominent (larger C and smaller APL). We also find that the delay strengthens the scale-free and small-world characteristics of DPFNs. In addition, we calculate and compare the mean first passage time (MFPT) numerically, revealing that the MFPT of DPFNs is shorter. Our study may help with a deeper understanding of various deterministically growing delayed networks

  17. Isotope techniques in studies of paleontology environmental reconstruction (vegetation and climate) in the delayed quaternario of two Brazilian regions

    This paper presents an attempt to reconstruct vegetation and climate changes in the central region of the state of Sao Paulo (Jaguariuna) and west of the state of Mato Grosso (Pontes e Lacerda) during the last 12,000 years BP, based on δ13C values of soil organic matter (SOM), 14 C dating and botanical identification of buried charcoal in the soil profiles. Sampling site in Sao Paulo was located under natural vegetation ('cerradao'), along the slope of small hills and in the top of slope under the semi-deciduous forest in Mato Grosso. Charcoal was found predominantly between 150 and 50 cm depth, indicating a period of greater frequency of fires in these regions, between 6,000 and 3,000 years BP. More enriched values of δ13C of SOM (predominance of C4 plants) were observed from approximately 12,000 to 7,000 years BP in Jaguariuna, indicating drier climate when compared with nowadays conditions. The charcoal analyses indicated the predominance of cerrado species. In Pontes e Lacerda site, the δ13C profile suggests the presence of C3 vegetation (forest) during the last 10,000 years and the most of identified charcoal fragments indicated the presence of semi-deciduous forest as well as cerrado species. (author)

  18. Delay in Contests

    Bester, Helmut; Konrad, Kai A.

    2003-01-01

    "Why is there delay in contests? In this paper we follow and extend the line of reasoning of Carl von Clausewitz to explain delay. For a given contest technology, delay may occur if there is an asymmetry between defense and attack, if the expected change in relative strengths is moderate, and if the additional cost of investment in future strength is low." (author's abstract) "In Konfliktsituationen findet der 'showdown' häufig mit einer Verzögerung statt. Das ist überraschend, weil sich m...

  19. Clustered chimera states in delay coupled oscillator systems

    Sethia, Gautam C.; Sen, Abhijit; Atay, Fatihcan M

    2008-01-01

    We investigate "chimera" states in a ring of identical phase oscillators coupled in a time-delayed and spatially non-local fashion. We find novel "clustered chimera" states that have spatially distributed phase coherence separated by incoherence with adjacent coherent regions in anti-phase. The existence of such time-delay induced phase clustering is further supported through solutions of a generalized functional self-consistency equation of the mean field. Our results highlight an additional...

  20. Delayed discharge.

    Allen, Daniel

    2016-07-01

    Essential facts Delays in discharging older peo ple from hospital cost the NHS £820 million a year, according to a report from the National Audit Office (NAO). Last year in acute hospitals, 1.15 million bed days were lost to delayed transfers of care, an increase of 31% since 2013. The NAO says rising demand for NHS services is compounded by reduced local authority spending on adult social care - down by 10% since 2009-10. PMID:27380673

  1. The effect of growing regions, microbiological fertilizers and soil additives on productivity of buckwheat (Fagopyrum esculentum Moench

    Dolijanović Željko K.

    2014-01-01

    Full Text Available This study was aimed at investigating the productivity of buckwheat taking into account growing regions, especially altitude, since this species does not have demanding soil requirements. The experiments were conducted during 2009 and 2010 in two localities: Valjevo (the village of Jasenica at 300 m altitude - 2009 and the village of Jovanja at 160 m altitude - 2010, and Nova Varos (the village of Radijevići at 1,065 m altitude. Soil of the experimental plots at both localities was characterized by acidic chemical reactions, with 3-5% of humus. In addition, the soil was rich in potassium, but poor in phosphorus. Within the objective test, with four replications, microbiological fertilizers Bactofil and Slavol were applied just before planting, alone or in combination with soil additives (hydrogel and zeolite. Half of each plot was fertilized foliarly, by the application of microbiological fertilizer Slavol using the concentrations of 50 ml per 10 liters of water. As compared with the control (no fertilizer application, in all variants of fertilization with a top dressing, increased grain yields were obtained. Significantly higher grain yields of buckwheat were obtained in the first locality, especially in the variant of fertilization with the combined use of Slavol and soil conditioner hydrogel. [Projekat Ministarstva nauke Republike Srbije, br. TR-31037

  2. Apollo 16 regolith breccias and soils - Recorders of exotic component addition to the Descartes region of the moon

    Simon, S. B.; Papike, J. J.; Laul, J. C.; Hughes, S. S.; Schmitt, R. A.

    1988-01-01

    Using the subdivision of Apollo 16 regolith breccias into ancient (about 4 Gyr) and younger samples (McKay et al., 1986), with the present-day soils as a third sample, a petrologic and chemical determination of regolith evolution and exotic component addition at the A-16 site was performed. The modal petrologies and mineral and chemical compositions of the regolith breccias in the region are presented. It is shown that the early regolith was composed of fragments of plutonic rocks, impact melt rocks, and minerals and impact glasses. It is found that KREEP lithologies and impact melts formed early in lunar history. The mare components, mainly orange high-TiO2 glass and green low-TiO2 glass, were added to the site after formation of the ancient breccias and prior to the formation of young breccias. The major change in the regolith since the formation of the young breccias is an increase in maturity represented by the formation of fused soil particles with prolonged exposure to micrometeorite impacts.

  3. Additional stratifications in the equatorial F region at dawn and dusk during geomagnetic storms: Role of electrodynamics

    Sreeja, V.; Balan, N.; Ravindran, Sudha; Pant, Tarun Kumar; Sridharan, R.; Bailey, G. J.

    2009-08-01

    The role of electrodynamics in producing additional stratifications in the equatorial F region (F 3 layer) at dawn and dusk during geomagnetic storms is discussed. Two cases of F 3 layer at dawn (0600-0730 LT on 5 October 2000 and 8 December 2000) and one case of F 3 layer at dusk (1600-1730 LT on 5 October 2000) are observed, for the first time, by the digital ionosonde at the equatorial station Trivandrum (8.5°N 77°E dip ˜ 0.5°N) in India. The unusual F 3 layers occurred during the geomagnetic storms and are associated with southward turning of interplanetary magnetic field B z , suggesting that eastward prompt penetration electric field could be the main cause of the F 3 layers. The dawn F 3 layer on 5 October is modeled using the Sheffield University Plasmasphere-Ionosphere Model by using the E × B drift estimated from the real height variation of the ionospheric peak during the morning period. The model qualitatively reproduces the dawn F 3 layer. While the existing F 2 layer rapidly drifts upward and forms the F 3 layer and topside ledge, a new layer forming at lower heights develops into the normal F 2 layer.

  4. Service Provider Competition: Delay Cost Structure, Segmentation, and Cost Advantage

    Maxim Afanasyev; Haim Mendelson

    2010-01-01

    We model competition between two providers who serve delay-sensitive customers. We compare a generalized delay cost structure, where a customer's delay cost depends on her service valuation, with the traditional additive delay cost structure, where the delay cost is independent of the customer's service valuation. Under the additive delay cost structure, service providers offer different prices and expected delays, but customers are indifferent between the providers. Under the generalized del...

  5. Prevention of an additional surgery for regional lymphadenectomy in melanoma: rapid intraoperative immunostaining of sentinel lymph node imprint smears

    Campbell Bruce H

    2006-09-01

    Full Text Available Abstract Background Sentinel lymph node (SLN biopsy is performed at many institutions and is considered a standard of care in the management of cutaneous melanoma. The discriminatory immunostaining pattern with the 'MCW Melanoma Cocktail' (a mixture of MART-1 {1:500}, Melan- A {1:100}, and Tyrosinase {1:50} monoclonal antibodies allows intraoperative immunocytochemical evaluation of imprint smears of SLNs for melanoma metastases. Cohesive cells of benign capsular melanocytic nevi that were also immunoreactive with the cocktail do not exfoliate easily for imprint smear detection. Methods We prospectively evaluated 73 lymph nodes (70 SLN & 3 non-SLN from 41 cases (mean 1.8, 1 to 4 SLNs/case of cutaneous melanoma using a rapid 17-minute immunostaining previously published protocol. The results were compared with permanent sections also immunostained with 'the cocktail'. Results 19.5%, 8/41 cases (12%, 9/73 lymph nodes were positive for melanoma metastases on permanent sections immunostained with the 'MCW melanoma cocktail'. Melanoma metastases in 87.5% (7/8 of these cases were also detected in rapidly immunostained imprint smears, with 100% specificity and 90% sensitivity. None of the 7 SLNs from 7 cases with capsular nevi showed false positive results. Conclusion Melanoma metastases could be detected in imprint smears immunostained with 'MCW Melanoma Cocktail' utilizing a rapid intraoperative protocol. The cohesive cells of the capsular nevi do not readily exfoliate and do not lead to false positive interpretation. In a majority of positive cases, a regional lymphadenectomy could have been completed during the same surgery for SLN biopsy and wide excision of primary melanoma site, potentially eliminating the need for an additional surgery.

  6. Stability analysis of multiple time-delayed system.

    Zheng, Da; Ren, Zhengyun; Fang, Jian-An

    2008-10-01

    A general class of linear time-invariant systems with time delays is studied. A number of methodologies have been suggested to assess the stability in the parametric domain of time delay or coefficient. This study offers an exact, structured and robust methodology to determine the stability regions of uncertain parameters in both time-delay space and coefficient space. The Rekasius transformation is used as a connection between time-delay space and coefficient space. An explicit analytical expression in terms of the system parameters which reveals the stability regions(pockets) in the domain of time delay and coefficient is presented. The method starts with the determination of all possible values of uncertain parameters which result in purely imaginary characteristic roots. In addition, some special stability boundaries are also discussed. After generating stability boundaries in parametric space, the two-step determination procedure is proposed to determine the actual stability regions. Such an approach can be used to determine the stability regions of any uncertain parameters of any retarded time-delay system. A complete example case study is also provided. PMID:18589418

  7. Delayed privatization

    Bernardo Bortolotti; Paolo Pinotti

    2008-01-01

    This paper studies the timing of privatization in 21 major developed economies in the 1977-2002 period. Duration analysis shows that political fragmentation plays a significant role in explaining government's decision to privatize: privatization is delayed longer in democracies characterized by a larger number of parties and operating under proportional electoral rules, as predicted by war of attrition models of economic reform. Results are robust to various assumptions on the underlying stat...

  8. Four patients with speech delay, seizures and variable corpus callosum thickness sharing a 0.440 Mb deletion in region 1q44 containing the HNRPU gene

    Caliebe, Almuth; Kroes, Hester Y.; van der Smagt, Jasper J.; Martin-Subero, Jose I.; Toennies, Holger; van 't Slot, Ruben; Nievelstein, Rutger A. J.; Muhle, Hiltrud; Stephani, Ulrich; Alfke, Karsten; Stefanova, Irina; Hellenbroich, Yorck; Gillessen-Kaesbach, Gabriele; Hochstenbach, Ron; Siebert, Reiner; Poot, Martin

    2010-01-01

    Structural genome aberrations are frequently associated with highly variable congenital phenotypes involving mental retardation and developmental delay. Although some of these aberrations may result in recognizable phenotypes, a high degree of phenotypic variability often complicates a comprehensive

  9. Synchronizing time delay systems using variable delay in coupling

    Highlights: → Delay and anticipation in coupling function varies with system dynamics. → Delay or anticipation of the synchronized state is independent of system delay. → Stability analysis developed is quite general. → We demonstrate enhanced security in communication. → Generalized synchronization possible over a wide range of parameter mismatch. - Abstract: We present a mechanism for synchronizing time delay systems using one way coupling with a variable delay in coupling that is reset at finite intervals. We present the analysis of the error dynamics that helps to isolate regions of stability of the synchronized state in the parameter space of interest for single and multiple delays. We supplement this by numerical simulations in a standard time delay system like Mackey Glass system. This method has the advantage that it can be adjusted to be delay or anticipatory in synchronization with a time which is independent of the system delay. We demonstrate the use of this method in communication using the bi channel scheme. We show that since the synchronizing channel carries information from transmitter only at intervals of reset time, it is not susceptible to an easy reconstruction.

  10. 77 FR 5714 - Change of Addresses for Regional Offices, Addition of One New Address, and Correction of Names of...

    2012-02-06

    ... Palau: Regional Director, U.S. Fish and Wildlife Service, 911 NE 11th Avenue, Portland, Oregon 97232... filing applications for ROWs over and across Service-administered lands and the terms and conditions.... 4321 et seq.; Executive Order 12630 (Takings); Executive Order 12866 (Regulatory Planning and...

  11. Dynamic Cournot Duopoly Game with Delay

    A. A. Elsadany

    2014-01-01

    Full Text Available The delay Cournot duopoly game is studied. Dynamical behaviors of the game are studied. Equilibrium points and their stability are studied. The results show that the delayed system has the same Nash equilibrium point and the delay can increase the local stability region.

  12. The effect of growing regions, microbiological fertilizers and soil additives on productivity of buckwheat (Fagopyrum esculentum Moench)

    Dolijanović Željko K.; Oljača Snežana I.; Kovačević Dušan Đ.; Šeremešić Srđan I.; Jovović Zoran M.

    2014-01-01

    This study was aimed at investigating the productivity of buckwheat taking into account growing regions, especially altitude, since this species does not have demanding soil requirements. The experiments were conducted during 2009 and 2010 in two localities: Valjevo (the village of Jasenica at 300 m altitude - 2009 and the village of Jovanja at 160 m altitude - 2010), and Nova Varos (the village of Radijevići at 1,065 m altitude). Soil of the experimental p...

  13. Optimum Delayed Retirement Credit

    Sheshinski, Eytan

    2002-01-01

    A central question for pension design is how benefits should vary with the age of retirement beyond early eligibility age. It is often argued that in order to be neutral with respect to individual retirement decisions benefits should be actuarially fair, that is, the present value of additional contributions and benefits (’Delayed Retirement Credit’ - DRC) due to postponed retirement should be equal. We show that in a self-selection, asymmetric information model, because individual decisions ...

  14. Reconstitution of the mitochondrial Hsp70 (mortalin)-p53 interaction using purified proteins--identification of additional interacting regions.

    Iosefson, Ohad; Azem, Abdussalam

    2010-03-19

    Previous studies have shown that the mammalian mitochondrial 70 kDa heat-shock protein (mortalin) can also be detected in the cytosol. Cytosolic mortalin binds p53 and by doing so, prevents translocation of the tumor suppressor into the nucleus. In this study, we developed a novel binding assay, using purified proteins, for tracking the interaction between p53 and mortalin. Our results reveal that: (i) P53 binds to the peptide-binding site of mortalin which enhances the ability of the former to bind DNA. (ii) An additional previously unknown binding site for mortalin exists within the C-terminal domain of p53. PMID:20153329

  15. Systematics in delayed neutron yields

    Ohsawa, Takaaki [Kinki Univ., Higashi-Osaka, Osaka (Japan). Atomic Energy Research Inst.

    1998-03-01

    An attempt was made to reproduce the systematic trend observed in the delayed neutron yields for actinides on the basis of the five-Gaussian representation of the fission yield together with available data sets for delayed neutron emission probability. It was found that systematic decrease in DNY for heavier actinides is mainly due to decrease of fission yields of precursors in the lighter side of the light fragment region. (author)

  16. Interferometric Propagation Delay

    Goldstein, Richard

    1999-01-01

    Radar interferometry based on (near) exact repeat passes has lately been used by many groups of scientists, worldwide, to achieve state of the art measurements of topography, glacier and ice stream motion, earthquake displacements, oil field subsidence, lava flows, crop-induced surface decorrelation, and other effects. Variations of tropospheric and ionospheric propagation delays limit the accuracy of all such measurements. We are investigating the extent of this limitation, using data from the Shuttle radar flight, SIR-C, which is sensitive to the troposphere, and the Earth Resources Satellites, ERS-1/2, which are sensitive to both the troposphere and the ionosphere. We are presently gathering statistics of the delay variations over selected, diverse areas to determine the best accuracy possible for repeat track interferometry. The phases of an interferogram depend on both the topography of the scene and variations in propagation delay. The delay variations can be caused by movement of elements in the scene, by changes in tropospheric water vapor and by changes of the charge concentrations in the ionosphere. We plan to separate these causes by using the data from a third satellite visit (three-pass interferometry). The figure gives the geometry of the three-pass observations. The page of the figure is taken to be perpendicular to the spacecraft orbits. The three observational locations are marked on the figure, giving baselines B-12 and B-13, separated by the angle alpha. These parameters are almost constant over the whole scene. However, each pixel has an individual look angle, theta, which is related to the topography, rho is the slant range. A possible spurious time delay is shown. Additional information is contained in the original.

  17. An examination of the origin and evolution of additional tandem repeats in the mitochondrial DNA control region of Japanese sika deer (Cervus Nippon).

    Ba, Hengxing; Wu, Lang; Liu, Zongyue; Li, Chunyi

    2016-01-01

    Tandem repeat units are only detected in the left domain of the mitochondrial DNA control region in sika deer. Previous studies showed that Japanese sika deer have more tandem repeat units than its cousins from the Asian continent and Taiwan, which often have only three repeat units. To determine the origin and evolution of these additional repeat units in Japanese sika deer, we obtained the sequence of repeat units from an expanded dataset of the control region from all sika deer lineages. The functional constraint is inferred to act on the first repeat unit because this repeat has the least sequence divergence in comparison to the other units. Based on slipped-strand mispairing mechanisms, the illegitimate elongation model could account for the addition or deletion of these additional repeat units in the Japanese sika deer population. We also report that these additional repeat units could be occurring in the internal positions of tandem repeat regions, possibly via coupling with a homogenization mechanism within and among these lineages. Moreover, the increased number of repeat units in the Japanese sika deer population could reflect a balance between mutation and selection, as well as genetic drift. PMID:24621225

  18. Beta-decay half-lives and beta-delayed neutron emission probabilities of nuclei in the region below A=110, relevant for the r-process

    Pereira, J; Aprahamian, A; Arndt, O; Becerril, A; Elliot, T; Estrade, A; Galaviz, D; Kessler, R; Kratz, K -L; Lorusso, G; Mantica, P F; Matos, M; Møller, P; Montes, F; Pfeiffer, B; Schatz, H; Schertz, F; Schnorrenberger, L; Smith, E; Stolz, A; Quinn, M; Walters, W B; Wöhr, A

    2009-01-01

    Measurements of the beta-decay properties of r-process nuclei below A=110 have been completed at the National Superconducting Cyclotron Laboratory, at Michigan State University. Beta-decay half-lives for Y-105, Zr-106,107 and Mo-111, along with beta-delayed neutron emission probabilities of Y-104, Mo-109,110 and upper limits for Y-105, Zr-103,104,105,106,107 and Mo-108,111 have been measured for the first time. Studies on the basis of the quasi-random phase approximation are used to analyze the ground-state deformation of these nuclei.

  19. Source Coding When the Side Information May Be Delayed

    Simeone, Osvaldo

    2011-01-01

    For memoryless sources, delayed side information at the decoder does not improve the rate-distortion function. However, this is not the case for more general sources with memory, as demonstrated by a number of works focusing on the special case of (delayed) feedforward. In this paper, a setting is studied in which the encoder is potentially uncertain about the delay with which measurements of the side information are acquired at the decoder. Assuming a hidden Markov model for the sources, at first, a single-letter characterization is given for the set-up where the side information delay is arbitrary and known at the encoder, and the reconstruction at the destination is required to be (near) lossless. Then, with delay equal to zero or one source symbol, a single-letter characterization is given of the rate-distortion region for the case where side information may be delayed or not, unbeknownst to the encoder. The characterization is further extended to allow for additional information to be sent when the side ...

  20. Effective multicasting algorithm for dynamic membership with delay constraint

    CHEN Lin; XU Zheng-quan

    2006-01-01

    This paper proposes an effective heuristic algorithm for dynamic multicast routing with delay-constrained DDMR.The tree constructed by DDMR has the following characteristics: (1) multicast tree changes with the dynamic memberships; (2)the cost of the tree is as small as possible at each node addition/removal event; (3) all of the path delay meet a fixed delay constraint;(4) minimal perturbation to an existing tree. The proposed algorithm is based on "damage" and "usefulness" concepts proposed in previous work, and has a new parameter bf(Balancing Factor) for judging whether or not to rearrange a tree region when membership changes. Mutation operation in Genetic Algorithm (GA) is also employed to find an attached node for a new adding node.Simulation showed that our algorithm performs well and is better than static heuristic algorithms, in term of cost especially.

  1. Precise delay measurement through combinatorial logic

    Burke, Gary R. (Inventor); Chen, Yuan (Inventor); Sheldon, Douglas J. (Inventor)

    2010-01-01

    A high resolution circuit and method for facilitating precise measurement of on-chip delays for FPGAs for reliability studies. The circuit embeds a pulse generator on an FPGA chip having one or more groups of LUTS (the "LUT delay chain"), also on-chip. The circuit also embeds a pulse width measurement circuit on-chip, and measures the duration of the generated pulse through the delay chain. The pulse width of the output pulse represents the delay through the delay chain without any I/O delay. The pulse width measurement circuit uses an additional asynchronous clock autonomous from the main clock and the FPGA propagation delay can be displayed on a hex display continuously for testing purposes.

  2. Sloppy Addition and Multiplication

    Nannarelli, Alberto

    Sometimes reducing the precision of a numerical processor, by introducing errors, can lead to significant performance (delay, area and power dissipation) improvements without compromising the overall quality of the processing. In this work, we show how to perform the two basic operations, addition...

  3. Coherent Pattern Prediction in Swarms of Delay-Coupled Agents

    Mier-Y-Teran-Romero, Luis; Forgoston, Eric; Scwartz, Ira

    2013-03-01

    We consider a general swarm model of self-propelling particles interacting through a pairwise potential in the presence of a fixed communication time delay. Previous work has shown that swarms with communication time delays and noise may display pattern transitions that depend on the size of the coupling amplitude. We extend these results by completely unfolding the bifurcation structure of the mean field approximation. Our analysis reveals a direct correspondence between the different dynamical behaviors found in different regions of the coupling-time delay plane with the different classes of simulated coherent swarm patterns. We derive the spatio-temporal scales of the swarm structures, and also demonstrate how the complicated interplay of coupling strength, time delay, noise intensity, and choice of initial conditions can affect the swarm. In addition, when adding noise to the system, we find that for sufficiently large values of the coupling strength and/or the time delay, there is a noise intensity threshold that forces a transition of the swarm from a misaligned state into an aligned state. We show that this alignment transition exhibits hysteresis when the noise intensity is taken to be time dependent. Office of Naval Research, NIH (LMR and IBS) and NRL (EF)

  4. Epidemic Spread and Variation of Peak Times in Connected Regions Due to Travel-Related Infections - Dynamics of an Antigravity-Type Delay Differential Model

    DH Knipl; G R\\xf6st; Wu, J.

    2013-01-01

    National boundaries have never prevented infectious diseases from reaching distant territories; however, the speed at which an infectious agent can spread around the world via the global airline transportation network has significantly increased during recent decades. We introduce an SEAIR-based, antigravity model to investigate the spread of an infectious disease in two regions which are connected by transportation. As a submodel, an age-structured system is constructed to incorporate the po...

  5. Delay Time in Quaternionic Quantum Mechanics

    De Leo, Stefano

    2012-01-01

    In looking for quaternionic violations of quantum mechanics, we discuss the delay time for pure quaternionic potentials. The study shows in which energy region it is possible to amplify the difference between quaternionic and complex quantum mechanics.

  6. Can the addition of regional radiotherapy counter-balance important risk factors in breast cancer patients with extracapsular invasion of axillary lymph-node metastases?

    Purpose: To evaluate if locoregional radiotherapy (RT) versus local irradiation only can alter the pattern of failure in breast cancer patients with extranodal invasion. Patients and Methods: From 08/1988 to 06/1998, 81 patients with extranodal invasion were treated with adjuvant RT (median total dose: 50.4 Gy), 46/81 only locally, 35/81 locoregionally due to presumed adverse parameters. The mean number of resected (positive) lymph nodes was 17 (seven). 78 patients received adjuvant systemic treatment(s). Results: Patients treated with locoregional RT had significantly more often lymphatic vessel invasion (LVI; 63% vs. 28%; p = 0.003), T3/T4 tumors (43% vs. 17%; p = 0.014), and four or more positive lymph nodes (91% vs. 46%; p < 0.001) than patients irradiated only locally. Disease progression occurred in 24/81 patients (locoregional RT: 26% vs. local RT: 33%). The above risk factors were highly significant of worse outcome. Despite their overrepresentation in the locoregional RT group, no difference was found between both groups in regard to disease-free survival (DFS; p = 0.83) and overall survival (OS; p = 0.56), suggesting that regional RT was able to counterbalance the increased risk. There was even a trend toward a better 3-year DFS, 61% in locoregional RT and 37% in local RT, in the subgroup of patients with four or more positive lymph nodes. In a Cox regression model, higher T-stage, four or more positive lymph nodes, and LVI remained significant. For DFS and distant metastasis-free survival (DMFS), the absence of estrogen receptors and the omission of regional RT were also significant. Conclusion: Our data suggest that the addition of regional RT might be beneficial in selected subgroups of patients with extranodal invasion and other poor prognostic factors. (orig.)

  7. Dimensional reduction of nonlinear time delay systems

    M. S. Fofana

    2005-01-01

    infinite-dimensional problem without the assumption of small time delay. This dimensional reduction is illustrated in this paper with the delay versions of the Duffing and van der Pol equations. For both nonlinear delay equations, transcendental characteristic equations of linearized stability are examined through Hopf bifurcation. The infinite-dimensional nonlinear solutions of the delay equations are decomposed into stable and centre subspaces, whose respective dimensions are determined by the linearized stability of the transcendental equations. Linear semigroups, infinitesimal generators, and their adjoint forms with bilinear pairings are the additional candidates for the infinite-dimensional reduction.

  8. Relative impact of previous disturbance history on the likelihood of additional disturbance in the Northern United States Forest Service USFS Region

    Hernandez, A. J.

    2015-12-01

    The Landsat archive is increasingly being used to detect trends in the occurrence of forest disturbance. Beyond information about the amount of area affected, forest managers need to know if and how disturbance regimes change. The National Forest System (NFS) has developed a comprehensive plan for carbon monitoring that requires a detailed temporal mapping of forest disturbances across 75 million hectares. A long-term annual time series that shows the timing, extent, and type of disturbance beginning in 1990 and ending in 2011 has been prepared for several USFS Regions, including the Northern Region. Our mapping starts with an automated detection of annual disturbances using a time series of historical Landsat imagery. Automated detections are meticulously inspected, corrected and labeled using various USFS ancillary datasets. The resulting maps of verified disturbance show the timing and types are fires, harvests, insect activity, disease, and abiotic (wind, drought, avalanche) damage. Also, the magnitude of each change event is modeled in terms of the proportion of canopy cover lost. The sequence of disturbances for every pixel since 1990 has been consistently mapped and is available across the entirety of NFS. Our datasets contain sufficient information to describe the frequency of stand replacement, as well as how often disturbance results in only a partial loss of canopy. This information provides empirical insight into how an initial disturbance may predispose a stand to further disturbance, and it also show a climatic signal in the occurrence of processes such as fire and insect epidemics. Thus, we have the information to model the likelihood of occurrence of certain disturbances after a given event (i.e. if we have a fire in the past what does that do to the likelihood of occurrence of insects in the future). Here, we explore if previous disturbance history is a reliable predictor of additional disturbance in the future and we present results of applying

  9. Delayed translational silencing of ceruloplasmin transcript in gamma interferon-activated U937 monocytic cells: role of the 3' untranslated region

    Mazumder, B.; Fox, P. L.

    1999-01-01

    Ceruloplasmin (Cp) is an acute-phase protein with ferroxidase, amine oxidase, and pro- and antioxidant activities. The primary site of Cp synthesis in human adults is the liver, but it is also synthesized by cells of monocytic origin. We have shown that gamma interferon (IFN-gamma) induces the synthesis of Cp mRNA and protein in monocytic cells. We now report that the induced synthesis of Cp is terminated by a mechanism involving transcript-specific translational repression. Cp protein synthesis in U937 cells ceased after 16 h even in the presence of abundant Cp mRNA. RNA isolated from cells treated with IFN-gamma for 24 h exhibited a high in vitro translation rate, suggesting that the transcript was not defective. Ribosomal association of Cp mRNA was examined by sucrose centrifugation. When Cp synthesis was high, i.e., after 8 h of IFN-gamma treatment, Cp mRNA was primarily associated with polyribosomes. However, after 24 h, when Cp synthesis was low, Cp mRNA was primarily in the nonpolyribosomal fraction. Cytosolic extracts from cells treated with IFN-gamma for 24 h, but not for 8 h, contained a factor which blocked in vitro Cp translation. Inhibitor expression was cell type specific and present in extracts of human cells of myeloid origin, but not in several nonmyeloid cells. The inhibitory factor bound to the 3' untranslated region (3'-UTR) of Cp mRNA, as shown by restoration of in vitro translation by synthetic 3'-UTR added as a "decoy" and detection of a binding complex by RNA gel shift analysis. Deletion mapping of the Cp 3'-UTR indicated an internal 100-nucleotide region of the Cp 3'-UTR that was required for complex formation as well as for silencing of translation. Although transcript-specific translational control is common during development and differentiation and global translational control occurs during responses to cytokines and stress, to our knowledge, this is the first report of translational silencing of a specific transcript following cytokine

  10. Delay in onset of metabolic alkalosis during regional citrate anti-coagulation in continous renal replacement therapy with calcium-free replacement solution

    See Kay

    2009-01-01

    Full Text Available Regional citrate anti-coagulation for continuous renal replacement therapy chelates calcium to produce the anti- coagulation effect. We hypothesise that a calcium-free replacement solution will require less citrate and produce fewer metabolic side effects. Fifty patients, in a Medical Intensive Care Unit of a tertiary teaching hospital (25 in each group, received continuous venovenous hemofiltration using either calcium-containing or calcium-free replacement solutions. Both groups had no significant differences in filter life, metabolic alkalosis, hypernatremia, hypocalcemia, and hypercalcemia. However, patients using calcium-containing solution developed metabolic alkalosis earlier, compared to patients using calcium-free solution (mean 24.6 hours,CI 0.8-48.4 vs. 37.2 hours, CI 9.4-65, P = 0.020. When calcium-containing replacement solution was used, more citrate was required (mean 280ml/h, CI 227.2-332.8 vs. 265ml/h, CI 203.4-326.6, P = 0.069, but less calcium was infused (mean 21.2 ml/h, CI 1.2-21.2 vs 51.6ml/h, CI 26.8-76.4, P ≤ 0.0001.

  11. Delayed Gambler's Ruin

    Imai, Tomohisa

    2016-01-01

    We present here a new extended model of the gambler's ruin problem by incorporating delays in receiving of rewards and paying of penalties. When there is a difference between two delays, an exact analysis of the ruin probability is difficult. We derive an approximate scheme to find an effective shift in the initial assets of the gambler. Through comparison against computer simulations, this approximation is shown to work for small differences between the two delays.

  12. VARIABLE TIME DELAY MEANS

    Clemensen, R.E.

    1959-11-01

    An electrically variable time delay line is described which may be readily controlled simuitaneously with variable impedance matching means coupied thereto such that reflections are prevented. Broadly, the delay line includes a signal winding about a magnetic core whose permeability is electrically variable. Inasmuch as the inductance of the line varies directly with the permeability, the time delay and characteristic impedance of the line both vary as the square root of the permeability. Consequently, impedance matching means may be varied similariy and simultaneously w:th the electrically variable permeability to match the line impedance over the entire range of time delay whereby reflections are prevented.

  13. Second Malignancies After Adjuvant Radiation Therapy for Early Stage Breast Cancer: Is There Increased Risk With Addition of Regional Radiation to Local Radiation?

    Hamilton, Sarah Nicole [Department of Surgery, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia (Canada); Department of Radiation Oncology, British Columbia Cancer Agency-Vancouver Centre, Vancouver, British Columbia (Canada); Tyldesley, Scott, E-mail: styldesl@bccancer.bc.ca [Department of Surgery, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia (Canada); Department of Radiation Oncology, British Columbia Cancer Agency-Vancouver Centre, Vancouver, British Columbia (Canada); Li, Dongdong [Cancer Control Research Department, British Columbia Cancer Agency-Vancouver Centre, Vancouver, British Columbia (Canada); Olson, Robert [Department of Radiation Oncology, British Columbia Cancer Agency-Centre for the North, Prince George, British Columbia (Canada); McBride, Mary [Cancer Control Research Department, British Columbia Cancer Agency-Vancouver Centre, Vancouver, British Columbia (Canada)

    2015-04-01

    Purpose: This study was undertaken to determine whether there was an increased risk of second malignancies (SM), particularly lung cancer, in early stage breast cancer patients treated with the addition of nodal fields to breast and/or chest wall radiation therapy (RT). Materials and Methods: Subjects were stage I/II female breast cancer patients 20 to 79 years of age, diagnosed between 1989 and 2005 and treated with adjuvant RT at our institution. Patients were included if they survived and did not have SM within 3 years of diagnosis. Standardized incidence ratios (SIR) with 95% confidence intervals (CI) were calculated to compare SM incidence to cancer incidence in the general sex- and age-matched populations. Secondary malignancy risks in patients treated with local RT (LRT) to the breast/chest wall were compared to those in patients treated with locoregional RT (LRRT) to the breast/chest wall and regional nodes, using multivariate regression analysis (MVA) to account for covariates. Results: The cohort included 12,836 patients with a median follow-up of 8.4 years. LRRT was used in 18% of patients. The SIR comparing patients treated with LRT to the general population was 1.29 (CI: 1.21-1.38). No statistically significant increased incidence of in-field malignancies (SIR, 1.04; CI: 0.87-1.23) and lung cancers (SIR, 1.06; CI: 0.88-1.26) was detected. The SIR comparing patients treated with LRRT to the general population was 1.39 (CI: 1.17-1.64). No statistically significant increased incidence of in-field malignancies (SIR, 1.26; CI: 0.77-1.94) and lung cancers (SIR, 1.27; CI: 0.76-1.98) was detected. On MVA comparing LRRT to LRT, the adjusted hazard ratio was 1.20 for in-field malignancies (CI: 0.68-2.16) and 1.26 for lung cancer (CI: 0.67-2.36). The excess attributable risk (EAR) to regional RT was 3.1 per 10,000 person years (CI: −8.7 to 9.9). Conclusions: No statistically significant increased risk of second malignancy was detected after LRRT relative to

  14. Second Malignancies After Adjuvant Radiation Therapy for Early Stage Breast Cancer: Is There Increased Risk With Addition of Regional Radiation to Local Radiation?

    Purpose: This study was undertaken to determine whether there was an increased risk of second malignancies (SM), particularly lung cancer, in early stage breast cancer patients treated with the addition of nodal fields to breast and/or chest wall radiation therapy (RT). Materials and Methods: Subjects were stage I/II female breast cancer patients 20 to 79 years of age, diagnosed between 1989 and 2005 and treated with adjuvant RT at our institution. Patients were included if they survived and did not have SM within 3 years of diagnosis. Standardized incidence ratios (SIR) with 95% confidence intervals (CI) were calculated to compare SM incidence to cancer incidence in the general sex- and age-matched populations. Secondary malignancy risks in patients treated with local RT (LRT) to the breast/chest wall were compared to those in patients treated with locoregional RT (LRRT) to the breast/chest wall and regional nodes, using multivariate regression analysis (MVA) to account for covariates. Results: The cohort included 12,836 patients with a median follow-up of 8.4 years. LRRT was used in 18% of patients. The SIR comparing patients treated with LRT to the general population was 1.29 (CI: 1.21-1.38). No statistically significant increased incidence of in-field malignancies (SIR, 1.04; CI: 0.87-1.23) and lung cancers (SIR, 1.06; CI: 0.88-1.26) was detected. The SIR comparing patients treated with LRRT to the general population was 1.39 (CI: 1.17-1.64). No statistically significant increased incidence of in-field malignancies (SIR, 1.26; CI: 0.77-1.94) and lung cancers (SIR, 1.27; CI: 0.76-1.98) was detected. On MVA comparing LRRT to LRT, the adjusted hazard ratio was 1.20 for in-field malignancies (CI: 0.68-2.16) and 1.26 for lung cancer (CI: 0.67-2.36). The excess attributable risk (EAR) to regional RT was 3.1 per 10,000 person years (CI: −8.7 to 9.9). Conclusions: No statistically significant increased risk of second malignancy was detected after LRRT relative to

  15. Improved LMI representations for delay-independent and delay-dependent stability conditions

    Yingmin JIA; Hideki Kokame

    2003-01-01

    Some new linear matrix inequality (LMI) representations for deley-independent and delay-dependent stability conditions are obtained by introducing additional matrices and eliminating the product coupling of the system matrices and the Lyapunov matrices. The results improve conservativeness of the given conditions for the analysis and the design of time-delay systems with polytopic-type uncertainty.

  16. Delay Banking for Managing Air Traffic

    Green, Steve

    2008-01-01

    Delay banking has been invented to enhance air-traffic management in a way that would increase the degree of fairness in assigning arrival, departure, and en-route delays and trajectory deviations to aircraft impacted by congestion in the national airspace system. In delay banking, an aircraft operator (airline, military, general aviation, etc.) would be assigned a numerical credit when any of their flights are delayed because of an air-traffic flow restriction. The operator could subsequently bid against other operators competing for access to congested airspace to utilize part or all of its accumulated credit. Operators utilize credits to obtain higher priority for the same flight, or other flights operating at the same time, or later, in the same airspace, or elsewhere. Operators could also trade delay credits, according to market rules that would be determined by stakeholders in the national airspace system. Delay banking would be administered by an independent third party who would use delay banking automation to continually monitor flights, allocate delay credits, maintain accounts of delay credits for participating airlines, mediate bidding and the consumption of credits of winning bidders, analyze potential transfers of credits within and between operators, implement accepted transfers, and ensure fair treatment of all participating operators. A flow restriction can manifest itself in the form of a delay in assigned takeoff time, a reduction in assigned airspeed, a change in the position for the aircraft in a queue of all aircraft in a common stream of traffic (e.g., similar route), a change in the planned altitude profile for an aircraft, or change in the planned route for the aircraft. Flow restrictions are typically imposed to mitigate traffic congestion at an airport or in a region of airspace, particularly congestion due to inclement weather, or the unavailability of a runway or region of airspace. A delay credit would be allocated to an operator of a

  17. Dynamic Network Delay Cartography

    Rajawat, Ketan; Giannakis, Georgios B

    2012-01-01

    Path delays in IP networks are important metrics, required by network operators for assessment, planning, and fault diagnosis. Monitoring delays of all source-destination pairs in a large network is however challenging and wasteful of resources. The present paper advocates a spatio-temporal Kalman filtering approach to construct network-wide delay maps using measurements on only a few paths. The proposed network cartography framework allows efficient tracking and prediction of delays by relying on both topological as well as historical data. Optimal paths for delay measurement are selected in an online fashion by leveraging the notion of submodularity. The resulting predictor is optimal in the class of linear predictors, and outperforms competing alternatives on real-world datasets.

  18. Food additives

    ... this page: //medlineplus.gov/ency/article/002435.htm Food additives To use the sharing features on this page, please enable JavaScript. Food additives are substances that become part of a food ...

  19. Ionospheric delay gradient monitoring for GBAS by GPS stations near Suvarnabhumi airport, Thailand

    Rungraengwajiake, Sarawoot; Supnithi, Pornchai; Saito, Susumu; Siansawasdi, Nattapong; Saekow, Apitep

    2015-10-01

    Ground-based augmentation system (GBAS) is an important augmentation system that provides the differential corrections and integrity information from the reference stations to the aircrafts for precision approach and landing. It is known that the nonuniform ionospheric characteristics called "ionospheric delay gradient" can cause the errors in differential corrections degrading the accuracy and safety level if they are undetected by the reference stations. Since the characteristics of the ionosphere are different for each region, the ionospheric delay gradient observations in equatorial and low-latitude regions are necessary for developing the suitable ionospheric threat models. The purpose of this work is to analyze the ionospheric delay gradients observed by three GPS stations near Suvarnabhumi airport in Bangkok, Thailand, which is located in the low-latitude region. The ionospheric irregularities in this region are mainly caused by the plasma bubble, which usually occurs after sunset. The GPS data with plasma bubble occurrence during the September equinox 2011 and 2012 are therefore analyzed. In addition, the data analysis procedure utilizing the rate of total electron content change index for this region is proposed. The results show that the ionospheric delay gradients observed in the west-east direction appear higher than the south-north direction, varying from 28 to 178 mm/km during plasma bubble occurrences.

  20. Discovery of a Plains Caldera Complex and Extinct Lava Lake in Arabia Terra, Mars: Implications for the Discovery of Additional Highland Volcanic Source Regions

    Bleacher, Jacob; Michalski, Joseph

    2012-01-01

    Several irregularly shaped topographic depressions occur near the dichotomy boundary in northern Arabia Terra, Mars. The geomorphology of these features suggests that they formed by collapse, opposed to meteor impact. At least one depression (approx.55 by 85 km) displays geologic features indicating a complex, multi-stage collapse history. Features within and around the collapse structure indicate volcanic processes. The complex occurs within Hesperian ridged plains of likely volcanic origin and displays no crater rim or evidence for ejecta. Instead the depression consists of a series of circumferential graben and down-dropped blocks which also display upper surfaces similar to ridged plain lavas. Large blocks within the depression are tilted towards the crater center, and display graben that appear to have originally been linked with circumferential graben outside of the complex related to earlier collapse events. A nearly 700 m high mound exists along a graben within the complex that might be a vent. The deepest depression displays two sets of nearly continuous terraces, which we interpret as high-stands of a drained lava lake. These features appear similar to the black ledge described during the Kilauea Iki eruption in 1959. A lacustrine origin for the terraces seems unlikely because of the paucity of channels found in or around the depression that could be linked to aqueous surface processes. In addition, there is no obvious evidence for lacustrine sediments within the basin. Together with the presence of significant faulting that is indicative of collapse we conclude that this crater complex represents a large caldera formed in the Late Noachian to Early Hesperian. Other linear and irregular depressions in the region also might be linked to ancient volcanism. If that hypothesis is correct, it suggests that northern Arabia Terra could contain a large, previously unrecognized highland igneous province. Evacuation of magma via explosive and effusive activity

  1. Finite time stabilization of delayed neural networks.

    Wang, Leimin; Shen, Yi; Ding, Zhixia

    2015-10-01

    In this paper, the problem of finite time stabilization for a class of delayed neural networks (DNNs) is investigated. The general conditions on the feedback control law are provided to ensure the finite time stabilization of DNNs. Then some specific conditions are derived by designing two different controllers which include the delay-dependent and delay-independent ones. In addition, the upper bound of the settling time for stabilization is estimated. Under fixed control strength, discussions of the extremum of settling time functional are made and a switched controller is designed to optimize the settling time. Finally, numerical simulations are carried out to demonstrate the effectiveness of the obtained results. PMID:26264170

  2. commensurate point delays

    M. de la Sen

    2005-01-01

    nominal controller is maintained. In the current approach, the finite spectrum assignment is only considered as a particular case of the designer's choice of a (delay-dependent arbitrary spectrum assignment objective.

  3. Ray-traced tropospheric total slant delays for GNSS processing

    Hobiger, T.; Ichikawa, R.; Hatanaka, Y.; Yutsudo, T.; Iwashita, C.; Miyahara, B.; Koyama, Y.; Kondo, T.

    2007-12-01

    Numerical weather models have undergone an improvement of spatial and temporal resolution in the recent years, which made their use for GNSS applications feasible. Ray-tracing through such models permits the computation of total troposphere delays and ray-bending angles. At the National Institute of Information and Communications Technology (NICT), Japan the so-called KAshima RAy-tracing Tools (KARAT) have been developed which allow to obtain troposphere delay corrections in real-time. Together with fine-mesh weather models from the Japanese Meteorological Agency (JMA) huge parts of the East Asian region, including Japan, Korea, Taiwan and East China, can be covered. The Japanese GEONET with its more than 1300 GNSS receivers represent an ideal test-bed for the evaluation of the performance of KARAT. In cooperation with the Geographical Survey Institute (GSI), Japan more than 1.6 billion observations, covering measurements from July 1st until August 31st, 2006, were processed and the corresponding troposphere delays were used to modify the original RINEX files by subtraction of code- and phase delays. These modified observations were processed by a dedicated analysis run of the GEONET operation center, taking advantage of the computer cluster at GSI. First results from this study, together with an in-depth discussion about the assets and drawbacks of the reduction of troposphere total slant delays will be given in this presentation. Additionally an overview about KARAT, the treatment of observational data and the impact of future refined numerical weather models on GNSS analysis will be included in this contribution.

  4. Calculating drain delay in high electron mobility transistors

    Coffie, R.

    2015-12-01

    An expression for the signal delay (drain delay) associated with electrons traveling through the gate-drain depletion region has been obtained for nonuniform electron velocity. Due to the presence of the gate metal, the signal delay through the gate-drain depletion region was shown to be larger than the signal delay in the base-collector depletion region of a bipolar transistor when equal depletion lengths and velocity profiles were assumed. Drain delay is also shown to be larger in transistors with field plates (independent of field plate connection) compared to transistors without field plates when equal depletion lengths and velocity profiles were assumed. For the case of constant velocity, two expressions for the proportionality constant relating drain delay and electron transit time across the depletion were obtained.

  5. Vernier Delay Unit

    This module will accept differential ECL pulses from the auxiliary rear panel or NIM level pulses from the front panel. The pulses are produced at the output with a fixed delay that is software programmable in steps of 0.1 ns over the range of 0.1 to 10.5 ns. Multiple outputs are available at the front panel. Minimum delay through the module is 9 ns

  6. Delayed Product Introduction

    Kai-Lung Hui; Qiu-Hong Wang

    2005-01-01

    We investigate the incentives of a monopolistic seller to delay the introduction of a new and improved version of his product. By analyzing a three-period model, we show that the seller may prefer to delay introducing a new product, even though the enabling technologies for the product are already available. The underlying motivation is analogous to that found in the durable goods monopolist literature – the seller suffers from a time inconsistency problem that causes his old and new products...

  7. Quad precision delay generator

    A Quad Precision Delay Generator delays a digital edge by a programmed amount of time, varying from nanoseconds to microseconds. The output of this generator has an amplitude of the order of tens of volts and rise time of the order of nanoseconds. This was specifically designed and developed to meet the stringent requirements of the plasma focus experiments. Plasma focus is a laboratory device for producing and studying nuclear fusion reactions in hot deuterium plasma. 3 figs

  8. An epidemic model of a vector-borne disease with direct transmission and time delay

    Wei, Hui-Ming; Li, Xue-Zhi; Martcheva, Maia

    2008-06-01

    This paper considers an epidemic model of a vector-borne disease which has direct mode of transmission in addition to the vector-mediated transmission. The incidence term is assumed to be of the bilinear mass-action form. We include both a baseline ODE version of the model, and, a differential-delay model with a discrete time delay. The ODE model shows that the dynamics is completely determined by the basic reproduction number R0. If R0[less-than-or-equals, slant]1, the disease-free equilibrium is globally stable and the disease dies out. If R0>1, a unique endemic equilibrium exists and is locally asymptotically stable in the interior of the feasible region. The delay in the differential-delay model accounts for the incubation time the vectors need to become infectious. We study the effect of that delay on the stability of the equilibria. We show that the introduction of a time delay in the host-to-vector transmission term can destabilize the system and periodic solutions can arise through Hopf bifurcation.

  9. Delayed radiation neuropathy

    A case of cervical plexus neuropathy was reported in association with chronic radio-dermatitis, myxedema with thyroid adenoma and epiglottic tumor. A 38-year-old man has noticed muscle weakness and wasting of the right shoulder girdle since age 33. A detailed history taking revealed a previous irradiation to the neck because of the cervical lymphadenopathy at age 10 (X-ray 3,000 rads), keroid skin change at age 19, obesity and edema since 26, and hoarseness at 34. Laryngoscopic examination revealed a tumor on the right vocal cord, diagnosed as benign papilloma by histological study. In addition, there were chronic radio-dermatitis around the neck, primary hypothyroidism with a benign functioning adenoma on the right lobe of the thyroid, the right phrenic nerve palsy and the right recurrent nerve palsy. All these lesions were considered to be the late sequellae of radiation to the neck in childhood. Other neurological signs were weakness and amyotrophy of the right shoulder girdle with patchy sensory loss, and areflexia of the right arm. Gross power was fairly well preserved in the right hand. EMG showed neurogenic changes in the tested muscles, suggesting a peripheral nerve lesion. Nerve conduction velocities were normal. No abnormal findings were revealed by myelography and spinal CT. The neurological findings of the patient were compatible with the diagnosis of middle cervical plexus palsy apparently due to late radiation effect. In the literature eight cases of post-radiation neuropathy with a long latency have been reported. The present case with the longest latency after the radiation should be included in the series of the reported cases of ''delayed radiation neuropathy.'' (author)

  10. Delayed recombination and standard rulers

    Measurements of baryonic acoustic oscillations (BAOs) in galaxy surveys have been recognized as a powerful tool for constraining dark energy. However, this method relies on the knowledge of the size of the acoustic horizon at recombination derived from cosmic microwave background (CMB) anisotropy measurements. This estimate is typically derived assuming a standard recombination scheme; additional radiation sources can delay recombination altering the cosmic ionization history and the cosmological inferences drawn from CMB and BAO data. In this paper we quantify the effect of delayed recombination on the determination of dark energy parameters from future BAO surveys such as the Baryon Oscillation Spectroscopic Survey and the Wide-Field Multi-Object Spectrograph. We find the impact to be small but still not negligible. In particular, if recombination is nonstandard (to a level still allowed by CMB data), but this is ignored, future surveys may incorrectly suggest the presence of a redshift-dependent dark energy component. On the other hand, in the case of delayed recombination, adding to the analysis one extra parameter describing deviations from standard recombination does not significantly degrade the error bars on dark energy parameters and yields unbiased estimates. This is due to the CMB-BAO complementarity.

  11. The Text of the Agreement of 20 August 1984 Extending the Asian Regional Co-Operative Project on Food Irradiation. Additional acceptance of the Second Extension Agreement

    A notification of acceptance of the Second Agreement to Extend the Agreement Establishing the Asian Regional Co-operative Project on Food Irradiation by the Governments of Sri Lanka was received by the Agency on 28 October 1985. Pursuant to Article II, paragraph 2, the Second Extension Agreement consequently entered into force on that date with respect to the Government of Sri Lanka

  12. The Text of the Agreement of 20 August 1984 Extending the Asian Regional Co-Operative Project on Food Irradiation. Additional acceptance of the Second Extension Agreement

    A notification of acceptance of the Second Agreement to Extend the Agreement Establishing the Asian Regional Co-operative Project on Food Irradiation by the Governments of the Philippines was received by the Agency on 25 September 1985. Pursuant to Article II, paragraph 2, the Second Extension Agreement consequently entered into force on that date with respect to the Government of the Philippines

  13. Ranking different factors influencing flight delay

    Meysam Kazemi Asfe

    2014-07-01

    Full Text Available Flight interruption is one of the most important issues in today’s airline industry. Every year, most airlines spend significant amount of money to compensate flight delays. Therefore, it is important to detect important factors influencing on flight delays. This paper presents an empirical investigation to determine important factors on this issue. The study also asks some decision makers to make pairwise comparison and ranks various factors using the art of analytical hierarchy process. The study determines that technical defects and delayed entry were among the most important factors to blame for flight delays. In addition, announcing the postponement, replacement aircraft and path replacement are among the most important decisions facing managers in the aviation industry during the disruption of the flight.

  14. Diagrammatic approach to attosecond delays in photoionization

    Dahlström, J M; Lindroth, E

    2012-01-01

    We study laser-assisted photoionization by attosecond pulses using a time-independent formalism based on diagrammatic many-body perturbation theory. Our aim is to provide an ab inito route to the "delays" for this above-threshold ionization process, which is essential for a quantitative understanding of attosecond metrology. We present correction curves for characterization schemes of attosecond pulses, such as "streaking", that account for the delayed atomic response in ionization from neon and argon. We also verify that photoelectron delays from many-electron atoms can be measured using similar schemes if, instead, the so-called continuum--continuum delay is subtracted. Our method is general and it can be extended also to more complex systems and additional correlation effects can be introduced systematically.

  15. The Agreement to Extend the Agreement 23 May 1980 Establishing the Asian Regional Co-Operative Project on Food Irradiation. Additional acceptances of the Agreement

    The Governments of the Philippines and India notified the Agency of their acceptance of the Agreement to Extend the Agreement Establishing the Asian Regional Co-operative Project on Food Irradiation of 8 July 1983, in accordance with Article II, paragraph 1 thereof, on 23 September 1983 and 27 September 1983 respectively. Pursuant to Article II, paragraph 2, the Extension Agreement consequently entered into force with respect to these Governments on the respective dates

  16. A new subfamily of penaeidin with an additional serine-rich region from kuruma shrimp (Marsupenaeus japonicus) contributes to antimicrobial and phagocytic activities.

    An, Ming-Yu; Gao, Jie; Zhao, Xiao-Fan; Wang, Jin-Xing

    2016-06-01

    Penaeidins are an important family of antimicrobial peptides (AMPs) in penaeid shrimp. To date, five groups of penaeidins have been identified in penaeid shrimp. All are composed of a proline-rich N-terminus and a C-terminus containing six cysteine residues engaged in three disulfide bridges. In this study, a new type of penaeidin from Marsupenaeus japonicus was identified. The full-length penaeidin contains a unique serine-rich region and a penaeidin domain, which consists of a proline-rich region and a cysteine-rich region. Here, we classify all penaeidins into two subfamilies. All reported penaeidins are in subfamily I, and the new penaeidin identified in M. japonicus is designated as Penaeidin subfamily II (MjPen-II). MjPen-II was expressed in hemocytes, heart, hepatopancreas, gills, stomach and intestine, and was upregulated after bacterial challenge. A liquid bacteriostatic assay showed that MjPen-II had antibacterial activity to some Gram-positive and Gram-negative bacteria. MjPen-II could bind to bacteria by binding to polysaccharides on the surface of bacteria, thus promoting bacterial agglutination. The serine-rich region enhanced the agglutination activity of MjPen-II. The proline-rich domain had a stronger bacterial-binding activity and polysaccharide-binding activity than the cysteine-rich domain. MjPen-II was also found to be involved in the phagocytosis of bacteria and efficiently improved the phagocytosis rate. Therefore, MjPen-II eliminates bacteria through direct bacterial inhibition as well as by promoting phagocytosis in shrimp. PMID:26855016

  17. The Text of a Regional Co-operative Agreement for Research, Development and Training related to Nuclear Science and Technology. Additional Acceptance of the Agreement

    The Governments of Indonesia, Thailand and the Philippines notified the Agency of their acceptance of the Regional Co-operative Agreement for Research, Development and Training Related to Nuclear Science and Technology between the Agency and Member States, in accordance with Section 9 thereof, on 16 October 1972, 4 December 1972 and 17 April 1973 respectively. Pursuant to Section 10, the Agreement consequently entered into force with respect to these Governments on the respective dates

  18. Additivity dominance

    Paul Rozin

    2009-10-01

    Full Text Available Judgments of naturalness of foods tend to be more influenced by the process history of a food, rather than its actual constituents. Two types of processing of a ``natural'' food are to add something or to remove something. We report in this study, based on a large random sample of individuals from six countries (France, Germany, Italy, Switzerland, UK and USA that additives are considered defining features of what makes a food not natural, whereas ``subtractives'' are almost never mentioned. In support of this, skim milk (with major subtraction of fat is rated as more natural than whole milk with a small amount of natural vitamin D added. It is also noted that ``additives'' is a common word, with a synonym reported by a native speaker in 17 of 18 languages, whereas ``subtractive'' is lexicalized in only 1 of the 18 languages. We consider reasons for additivity dominance, relating it to omission bias, feature positive bias, and notions of purity.

  19. The WNT2 Gene Polymorphism Associated with Speech Delay Inherent to Autism

    Lin, Ping-I; Chien, Yi-Ling; Wu, Yu-Yu; Chen, Chia-Hsiang; Gau, Susan Shur-Fen; Huang, Yu-Shu; Liu, Shih-Kai; Tsai, Wen-Che; Chiu, Yen-Nan

    2012-01-01

    Previous evidence suggests that language function is modulated by genetic variants on chromosome 7q31-36. However, it is unclear whether this region harbors loci that contribute to speech delay in autism. We previously reported that the WNT2 gene located on 7q31 was associated with the risk of autism. Additionally, two other genes on 7q31-36,…

  20. Time Delay Cosmography

    Treu, Tommaso

    2016-01-01

    Gravitational time delays, observed in strong lens systems where the variable background source is multiply-imaged by a massive galaxy in the foreground, provide direct measurements of cosmological distance that are very complementary to other cosmographic probes. The success of the technique depends on the availability and size of a suitable sample of lensed quasars or supernovae, precise measurements of the time delays, accurate modeling of the gravitational potential of the main deflector, and our ability to characterize the distribution of mass along the line of sight to the source. We review the progress made during the last 15 years, during which the first competitive cosmological inferences with time delays were made, and look ahead to the potential of significantly larger lens samples in the near future.

  1. Delayed breast implant reconstruction

    Hvilsom, Gitte B.; Hölmich, Lisbet R.; Steding-Jessen, Marianne;

    2011-01-01

    -stage procedures. From the Danish Registry for Plastic Surgery of the Breast, which has prospectively registered data for women undergoing breast implantations since 1999, we identified 559 women without a history of radiation therapy undergoing 592 delayed breast reconstructions following breast cancer during the......Studies of complications following reconstructive surgery with implants among women with breast cancer are needed. As the, to our knowledge, first prospective long-term study we evaluated the occurrence of complications following delayed breast reconstruction separately for one- and two...

  2. Approximation of distributed delays

    Lu, Hao; Eberard, Damien; Simon, Jean-Pierre

    2010-01-01

    We address in this paper the approximation problem of distributed delays. Such elements are convolution operators with kernel having bounded support, and appear in the control of time-delay systems. From the rich literature on this topic, we propose a general methodology to achieve such an approximation. For this, we enclose the approximation problem in the graph topology, and work with the norm defined over the convolution Banach algebra. The class of rational approximates is described, and a constructive approximation is proposed. Analysis in time and frequency domains is provided. This methodology is illustrated on the stabilization control problem, for which simulations results show the effectiveness of the proposed methodology.

  3. Regional dGEMRIC analysis in patients at risk of osteoarthritis provides additional information about activity related changes in cartilage structure

    Hawezi, Z K; Lammentausta, E; Svensson, J; Roos, E M; Dahlberg, L E; Tiderius, C J

    2016-01-01

    . PURPOSE: To improve the knowledge about exercise effects on cartilage structure by re-analyzing previous images with regional dGEMRIC analysis. MATERIAL AND METHODS: Thirty patients (age range, 38-50 years) with a previous medial meniscus resection were divided into three groups according to self...... joint, the largest improvement being observed in lateral posterior cartilage, i.e. the load-bearing cartilage in the compartment without a meniscus lesion. The effects of exercise do not seem to vary with cartilage depth....

  4. Global exponential synchronization of nonlinear time-delay Lur'e systems via delayed impulsive control

    Chen, Wu-Hua; Wei, Dan; Lu, Xiaomei

    2014-09-01

    This paper is concerned with the global exponential synchronization problem of two identical nonlinear time-delay Lur'e systems via delayed impulsive control. Some novel impulsive synchronization criteria are obtained by introducing a discontinuous Lyapunov function and by using the Lyapunov-Razumikhin technique, which are expressed in forms of linear matrix inequalities. The derived criteria reveal the effects of impulsive input delays and impulsive intervals on the stability of synchronization error systems. Then, sufficient conditions on the existence of a delayed impulsive controller are derived by employing these newly-obtained synchronization criteria. Additionally, some synchronization criteria for two identical time-delay Lur'e systems with impulsive effects are presented by using delayed continuous feedback control. The synchronization criteria via delayed continuous feedback control can deal with the case when the impulsive control strategy fails to synchronize two identical impulsive time-delay Lur'e systems. Three numerical examples are provided to illustrate the efficiency of the obtained results.

  5. Controller design for delay-independent stability of linear time-invariant vibration systems with multiple delays

    Mahmoodi Nia, Payam; Sipahi, Rifat

    2013-07-01

    One of the critical parameters that can deteriorate the effectiveness of active vibration control (AVC) is the delay in sensors. Especially, in remote sensing where delays are large, and in high-speed applications with even small delays, instability can be inevitable. This paper presents algebraic approaches to design controllers in order to achieve stability regardless of the amount of delays for AVC applications modeled by linear time-invariant systems with "multiple" constant delays. The approaches are based on a nonconservative framework, and can identify the regions in the controller gain space where delay-independent stability (DIS) is achievable. With these controllers, we demonstrate via simulations that vibration suppression, within certain excitation frequency bands, can be improved or be as effective as those in AVC applications without delays.

  6. Delayed recombination and cosmic parameters

    Current cosmological constraints from cosmic microwave background anisotropies are typically derived assuming a standard recombination scheme, however additional resonance and ionizing radiation sources can delay recombination, altering the cosmic ionization history and the cosmological inferences drawn from the cosmic microwave background data. We show that for recent observations of the cosmic microwave background anisotropy, from the Wilkinson microwave anisotropy probe satellite mission (WMAP) 5-year survey and from the arcminute cosmology bolometer array receiver experiment, additional resonance radiation is nearly degenerate with variations in the spectral index, ns, and has a marked effect on uncertainties in constraints on the Hubble constant, age of the universe, curvature and the upper bound on the neutrino mass. When a modified recombination scheme is considered, the redshift of recombination is constrained to z*=1078±11, with uncertainties in the measurement weaker by 1 order of magnitude than those obtained under the assumption of standard recombination while constraints on the shift parameter are shifted by 1σ to R=1.734±0.028. From the WMAP5 data we obtain the following constraints on the resonance and ionization sources parameters: εαi<0.058 at 95% c.l.. Although delayed recombination limits the precision of parameter estimation from the WMAP satellite, we demonstrate that this should not be the case for future, smaller angular scales measurements, such as those by the Planck satellite mission.

  7. Asynchronous Bounded Expected Delay Networks

    Bakhshi, Rena; Endrullis, Jörg; Fokkink, Wan; Pang, Jun

    2010-01-01

    The commonly used asynchronous bounded delay (ABD) network models assume a fixed bound on message delay. We propose a probabilistic network model, called asynchronous bounded expected delay (ABE) model. Instead of a strict bound, the ABE model requires only a bound on the expected message delay. While the conditions of ABD networks restrict the set of possible executions, in ABE networks all asynchronous executions are possible, but executions with extremely long delays are less probable. In ...

  8. Additivity dominance

    Paul Rozin; Claude Fischler; Christy Shields-Argeles

    2009-01-01

    Judgments of naturalness of foods tend to be more influenced by the process history of a food, rather than its actual constituents. Two types of processing of a ``natural'' food are to add something or to remove something. We report in this study, based on a large random sample of individuals from six countries (France, Germany, Italy, Switzerland, UK and USA) that additives are considered defining features of what makes a food not natural, whereas ``subtractives'' are almost never mentioned....

  9. Restarting delayed nuclear power plant projects

    The management of nuclear power plant projects with delays of several years with respect to the original scheduled commercial operation date presents particular issues and problem areas beyond the normal management tasks needed for projects implemented within originally planned schedules. During the years 1997-1998 the IAEA collected information and practical examples on necessary management actions to preserve the capability for resuming work and completing delayed nuclear power projects when conditions permit. The results were published in the IAEA-TECDOC-1110 entitled Management of Delayed Nuclear Power Plant Projects. As this publication was finalized, at the end of 1998, the available information at the IAEA PRIS (Power Reactor Information System) indicated that more than 40 nuclear power plant projects had delays of five or more years with respect to the originally scheduled operation dates. The PRIS data, collected at the end of 2007, illustrates a trend toward restarting and completing projects that were once delayed. The data indicates that the number of delayed nuclear power projects has reduced to about 25. Some practical methodologies and successful experience from the restarted projects were reviewed, summarized and included in the present publication. The purpose is to address the specific management issues pertaining to a delayed nuclear power project in the period after the decision for restarting is adopted. This publication covers those management issues not considered within the normal processes described in other IAEA publications. It is expected that the practical experience collected from delayed nuclear power projects that were successfully restarted, completed and brought to commercial operation, can provide useful assistance to the management of similar projects considering resumption of work in the future. This publication was produced within the IAEA programme directed to increase the capability of Member States for strengthening national

  10. Dragonflies and damselflies (Insecta: Odonata of the northeastern region of Bangladesh with five new additions to the Odonata fauna of Bangladesh

    M. Kawsar Khan

    2015-09-01

    Full Text Available Odonata were surveyed in one reserve forest, two national parks, one Eco Park, one lake and one University campus in the northeastern region of Bangladesh from March 2014 to March 2015.  A total of 64 species of Anisoptera and Zygoptera belonging to 41 genera under seven families were recorded.  Among them 45 species and 19 genera were new records for the study area.  Two species of Anisoptera, i.e., Anax indicus Lieftinck, 1942 and Gynacantha khasiaca MacLachlan, 1896, and three species of Zygoptera i.e., Matrona nigripectus Selys, 1879, Agriocnemis kalinga Nair & Subramanian, 2014, and Prodasineura laidlawii Forster, 1907 were recorded for the first time from Bangladesh.  

  11. Delayed traumatic diaphragmatic hernia

    Lu, Jing; Wang, Bo; Che, Xiangming; Li, Xuqi; Qiu, Guanglin; He, Shicai; Fan, Lin

    2016-01-01

    Abstract Background: Traumatic diaphragmatic hernias (TDHs) are sometimes difficult to identify at an early stage and can consequently result in diagnostic delays with life-threatening outcomes. It is the aim of this case study to highlight the difficulties encountered with the earlier detection of traumatic diaphragmatic hernias. Methods: Clinical data of patients who received treatment for delayed traumatic diaphragmatic hernias in registers of the First Affiliated Hospital of Xi’an Jiaotong University from 1998 to 2014 were analyzed retrospectively. Results: Six patients were included in this study. Left hemidiaphragm was affected in all of them. Most of the patients had a history of traffic accident and 1 a stab-penetrating injury. The interval from injury to developing symptoms ranged from 2 to 11 years (median 5 years). The hernial contents included the stomach, omentum, small intestine, and colon. Diaphragmatic injury was missed in all of them during the initial managements. All patients received operations once the diagnosis of delayed TDH was confirmed, and no postoperative mortality was detected. Conclusions: Delayed TDHs are not common, but can lead to serious consequences once occurred. Early detection of diaphragmatic injuries is crucial. Surgeons should maintain a high suspicion for injuries of the diaphragm in cases with abdominal or lower chest traumas, especially in the initial surgical explorations. We emphasize the need for radiographical follow-up to detect diaphragmatic injuries at an earlier stage. PMID:27512848

  12. Speech and Language Delay

    ... child depends on the cause of the speech delay. Your doctor will tell you the cause of your child's problem and explain any treatments that might fix the problem or make it better. A speech and language pathologist might be helpful in making treatment plans. This ...

  13. Ignition Delay Studies on Hypergolic Fuel Grains

    S. R. Jain

    1988-07-01

    Full Text Available The ignition delays of several solid hypergolic fuel compositions, casted using various polymeric binders, or as melts, have been determined with fuming nitric acid as oxidizer. The ignition delays of various hypergolic fuel compositions increase drasticaliy on casting with binders like. carboxyl or hydroxyl termninated polybutadiene. Fuel grains cast using some newly syhthesised epoxy  resins with other ingrcdients, such as curing agent, magnesium powder and fuel, have short ignition delays of the order of 200 ms, and also good mechanical strength. Increasing the amount of binder in the composition retards the hypergolicity of the rain. Similar studies have been made on melt-cast systems using low melting hypergolic fuels for casting fuel powders. The ignition delays of the melt-cast grains, are longer than those determined taking the composition in the powder form. The effect of highly hypergolic additives, and metal powders, on the ignition delay of the cast compositions has been determined. Grains having good mechanical strength and short ignition delays have been obtained by optimising the fuel grain composition.

  14. Stability analysis of a class of fractional delay differential equations

    Sachin B Bhalekar

    2013-08-01

    In this paper we analyse stability of nonlinear fractional order delay differential equations of the form $D^{} y(t) = af(y(t - )) - {\\text{by}} (t)$, where $D^{}$ is a Caputo fractional derivative of order 0 < ≤ 1. We describe stability regions using critical curves. To explain the proposed theory, we discuss fractional order logistic equation with delay.

  15. Various Forms of Project Delay in the Construction Industry

    Nurbasirah Mohamed Alias; Md Azree Othuman Mydin

    2013-01-01

    Project delay can be defined as an incident that causes extended time in order to complete all or part of a particular project successfully. In other words, delay is the time overrun, either ahead of the date for project completion specified by the contract or further than the extensive contract period where an addition of time has been granted. It should be pointed out that the project delay in the construction industry is a universal or large-scale observable fact affectin...

  16. Whole heart coronary imaging with flexible acquisition window and trigger delay.

    Keigo Kawaji

    Full Text Available Coronary magnetic resonance imaging (MRI requires a correctly timed trigger delay derived from a scout cine scan to synchronize k-space acquisition with the quiescent period of the cardiac cycle. However, heart rate changes between breath-held cine and free-breathing coronary imaging may result in inaccurate timing errors. Additionally, the determined trigger delay may not reflect the period of minimal motion for both left and right coronary arteries or different segments. In this work, we present a whole-heart coronary imaging approach that allows flexible selection of the trigger delay timings by performing k-space sampling over an enlarged acquisition window. Our approach addresses coronary motion in an interactive manner by allowing the operator to determine the temporal window with minimal cardiac motion for each artery region. An electrocardiogram-gated, k-space segmented 3D radial stack-of-stars sequence that employs a custom rotation angle is developed. An interactive reconstruction and visualization platform is then employed to determine the subset of the enlarged acquisition window for minimal coronary motion. Coronary MRI was acquired on eight healthy subjects (5 male, mean age = 37 ± 18 years, where an enlarged acquisition window of 166-220 ms was set 50 ms prior to the scout-derived trigger delay. Coronary visualization and sharpness scores were compared between the standard 120 ms window set at the trigger delay, and those reconstructed using a manually adjusted window. The proposed method using manual adjustment was able to recover delineation of five mid and distal right coronary artery regions that were otherwise not visible from the standard window, and the sharpness scores improved in all coronary regions using the proposed method. This paper demonstrates the feasibility of a whole-heart coronary imaging approach that allows interactive selection of any subset of the enlarged acquisition window for a tailored reconstruction

  17. Calibration of Low-Frequency, Wide-Field Radio Interferometers Using Delay/Delay-Rate Filtering

    Parsons, Aaron R

    2009-01-01

    We present a filtering technique that can be applied to individual baselines of wide-bandwidth, wide-field interferometric data to geometrically select regions on the celestial sphere that contain primary calibration sources. The technique relies on the Fourier transformation of wide-band frequency spectra from a given baseline to obtain one-dimensional "delay images", and then the transformation of a time-series of delay images to obtain two-dimensional "delay/delay-rate images." Source selection is possible in these images given appropriate combinations of baseline, bandwidth, integration time and source location. Strong and persistent radio frequency interference (RFI) limits the effectiveness of this source selection owing to the removal of data by RFI excision algorithms. A one-dimensional, complex CLEAN algorithm has been developed to compensate for RFI-excision effects. This approach allows CLEANed, source-isolated data to be used to isolate bandpass and primary beam gain functions. These techniques ar...

  18. Refinement of the Region for Split Hand/Foot Malformation 5 on 2q31.1

    Theisen, A.; Rosenfeld, J.A.; Shane, K.; McBride, K.L.; Atkin, J F; Gaba, C.; Hoo, J.; Kurczynski, T W; Schnur, R. E.; Coffey, L.B.; Zackai, E H; Schimmenti, L.; Friedman, N.; Zabukovec, M.; Ball, S

    2011-01-01

    Background: Deletions that encompass 2q31.1 have been proposed as a microdeletion syndrome with common clinical features, including intellectual disability/developmental delay, microcephaly, cleft palate, growth delay, and hand/foot anomalies. In addition, several genes within this region have been proposed as candidates for split hand-foot malformation 5 (SHFM5). Methods: To delineate the genotype-phenotype correlation between deletions of this region, we identified 14 individuals with delet...

  19. Delay reduction: current status.

    Fantino, E; Preston, R. A.; Dunn, R

    1993-01-01

    Delay-reduction theory states that the effectiveness of a stimulus as a conditioned reinforcer may be predicted most accurately by the reduction in time to primary reinforcement correlated with its onset. We review support for the theory and then discuss two new types of experiments that assess it. One compares models of choice in situations wherein the less preferred outcome is made more accessible; the other investigates whether frequency of conditioned reinforcement affects choice beyond t...

  20. Time-Delay Interferometry

    Dhurandhar, Sanjeev V.; Tinto, Massimo

    2005-07-01

    Equal-arm interferometric detectors of gravitational radiation allow phase measurements many orders of magnitude below the intrinsic phase stability of the laser injecting light into their arms. This is because the noise in the laser light is common to both arms, experiencing exactly the same delay, and thus cancels when it is differenced at the photo detector. In this situation, much lower level secondary noises then set the overall performance. If, however, the two arms have different lengths (as will necessarily be the case with space-borne interferometers), the laser noise experiences different delays in the two arms and will hence not directly cancel at the detector. In order to solve this problem, a technique involving heterodyne interferometry with unequal arm lengths and independent phase-difference readouts has been proposed. It relies on properly time-shifting and linearly combining independent Doppler measurements, and for this reason it has been called Time-Delay Interferometry (TDI). This article provides an overview of the theory and mathematical foundations of TDI as it will be implemented by the forthcoming space-based interferometers such as the Laser Interferometer Space Antenna (LISA) mission. We have purposely left out from this first version of our "Living Review" article on TDI all the results of more practical and experimental nature, as well as all the aspects of TDI that the data analysts will need to account for when analyzing the LISA TDI data combinations. Our forthcoming "second edition" of this review paper will include these topics.

  1. Time-Delay Interferometry

    Massimo Tinto

    2014-08-01

    Full Text Available Equal-arm detectors of gravitational radiation allow phase measurements many orders of magnitude below the intrinsic phase stability of the laser injecting light into their arms. This is because the noise in the laser light is common to both arms, experiencing exactly the same delay, and thus cancels when it is differenced at the photo detector. In this situation, much lower level secondary noises then set the overall performance. If, however, the two arms have different lengths (as will necessarily be the case with space-borne interferometers, the laser noise experiences different delays in the two arms and will hence not directly cancel at the detector. In order to solve this problem, a technique involving heterodyne interferometry with unequal arm lengths and independent phase-difference readouts has been proposed. It relies on properly time-shifting and linearly combining independent Doppler measurements, and for this reason it has been called time-delay interferometry (TDI. This article provides an overview of the theory, mathematical foundations, and experimental aspects associated with the implementation of TDI. Although emphasis on the application of TDI to the Laser Interferometer Space Antenna (LISA mission appears throughout this article, TDI can be incorporated into the design of any future space-based mission aiming to search for gravitational waves via interferometric measurements. We have purposely left out all theoretical aspects that data analysts will need to account for when analyzing the TDI data combinations.

  2. Numerical Investigation of Noise Enhanced Stability Phenomenon in a Time-Delayed Metastable System

    JIA Zheng-Lin

    2008-01-01

    @@ The transient properties of a time-delayed metastable system subjected to the additive white noise are investigated by means of the stochastic simulation method. The noise enhanced stability phenomenon (NES) can be observed in this system and the effect of the delay time on the NES shows a critical behaviour, i.e., there is a critical value of the delay time Tc ≈ 1, above which the time delay enhances the NES effect with the delay time increasing and below which the time delay weakens the NES effect as the delay time increases.

  3. Numerical Investigation of Noise Enhanced Stability Phenomenon in a Time-Delayed Metastable System

    The transient properties of a time-delayed metastable system subjected to the additive white noise are investigated by means of the stochastic simulation method. The noise enhanced stability phenomenon (NES) can be observed in this system and the effect of the delay time on the NES shows a critical behaviour, i.e., there is a critical value of the delay time τc ≈ 1, above which the time delay enhances the NES effect with the delay time increasing and below which the time delay weakens the NES effect as the delay time increases

  4. Current Vaccine Shortages and Delays

    ... CDC.gov . Vaccines and Immunizations Share Compartir Current Vaccine Shortages & Delays Last Updated December 7, 2015 On ... schedule are included in this update. Chart of Vaccines* in Delay or Shortage Vaccines are listed in ...

  5. Impulsivity Relates To Striatal Gray Matter Volumes In Humans: Evidence From A Delay Discounting Paradigm

    Melanie eTschernegg

    2015-07-01

    Full Text Available Time-stable personality traits, such as impulsivity and its relationship with functional and structural brain alterations, have gained much attention in the recent literature. Evidence from functional neuroimaging data implies an association between impulsivity and cortical as well as subcortical areas of the reward system. Discounting future rewards during impulsive decisions can be related to activation in the orbitofrontal cortex and striatum. Cortical structural changes in prefrontal regions have been found for introspective impulsivity measures. The present study focuses on brain regions associated with delay discounting to investigate structural manifestations of trait impulsivity. To test this, seventy subjects underwent structural MRI followed by a behavioural delay discounting task outside of the scanner to measure impulsivity with questions like: Would you like to have 3 € immediately or 10 € in five days?. The amount of smaller-but-sooner decisions was calculated and used as a measure of behavioural impulsivity. Furthermore, we estimated subject’s individual delay discounting parameter K reflecting the tendency to discount future rewards. Behaviourally, we found strong evidence in favour of a discounting utility model compared to a standard hyperbolic model of choice valuation. Neuronally, we focused on cortical and subcortical brain structure and investigated the association of behavioural impulsivity with delay discounting tendencies and gray matter volume. Voxel-based morphometric analyses showed positive correlations between delay discounting and gray matter volume in the striatum. Additional analyses using Freesurfer provided evidence for a positive correlation between delay discounting and gray matter volume of the caudate. Taken together, our study provides strong evidence for a structural manifestation of time-stable trait impulsivity in the human brain.

  6. Stimulus-dependent synchronization in delayed-coupled neuronal networks.

    Esfahani, Zahra G; Gollo, Leonardo L; Valizadeh, Alireza

    2016-01-01

    Time delay is a general feature of all interactions. Although the effects of delayed interaction are often neglected when the intrinsic dynamics is much slower than the coupling delay, they can be crucial otherwise. We show that delayed coupled neuronal networks support transitions between synchronous and asynchronous states when the level of input to the network changes. The level of input determines the oscillation period of neurons and hence whether time-delayed connections are synchronizing or desynchronizing. We find that synchronizing connections lead to synchronous dynamics, whereas desynchronizing connections lead to out-of-phase oscillations in network motifs and to frustrated states with asynchronous dynamics in large networks. Since the impact of a neuronal network to downstream neurons increases when spikes are synchronous, networks with delayed connections can serve as gatekeeper layers mediating the firing transfer to other regions. This mechanism can regulate the opening and closing of communicating channels between cortical layers on demand. PMID:27001428

  7. The Cost of Delaying Approval of Golden Rice

    Wesseler, J.H.H.; Kaplan, S; Zilberman, D.

    2014-01-01

    More than 250,000 children go blind every year because of Vitamin A deficiency. Vitamin A intake can be enhanced by consuming Golden Rice—a genetically engineered variety of rice. It was available for commercialization in 2002, but approval has been delayed. We estimate that this delay has resulted in 600,000 to 1.2 million additional cases of blindness.

  8. Synchronization Stability in Weighted Complex Networks with Coupling Delays

    WANG Qing-Yun; DUAN Zhi-Sheng; CHEN Guan-Rong; LU Qi-Shao

    2009-01-01

    Realistic networks display not only a complex topological structure, but also a heterogeneous distribution of weights in connection strengths.In addition, the information spreading through a complex network is often associated with time delays due to the finite speed of signal transmission over a distance.Hence, the weighted complex network with coupling delays have meaningful implications in real world, and resultantly ga/ns increasing attention in various fields of science and engineering.Based on the theory of asymptotic stability of linear time-delay systems, synchronization stability of the weighted complex dynamical network with coupling delays is investigated, and simple criteria are obtained for both delay-independent and delay-dependent stabilities of synchronization states.The obtained criteria in this paper encompass the established results in the literature as special cases.Some examples are given to illustrate the theoretical results.

  9. GENERAL: Synchronization Stability in Weighted Complex Networks with Coupling Delays

    Wang, Qing-Yun; Duan, Zhi-Sheng; Chen, Guan-Rong; Lu, Qi-Shao

    2009-04-01

    Realistic networks display not only a complex topological structure, but also a heterogeneous distribution of weights in connection strengths. In addition, the information spreading through a complex network is often associated with time delays due to the finite speed of signal transmission over a distance. Hence, the weighted complex network with coupling delays have meaningful implications in real world, and resultantly gains increasing attention in various fields of science and engineering. Based on the theory of asymptotic stability of linear time-delay systems, synchronization stability of the weighted complex dynamical network with coupling delays is investigated, and simple criteria are obtained for both delay-independent and delay-dependent stabilities of synchronization states. The obtained criteria in this paper encompass the established results in the literature as special cases. Some examples are given to illustrate the theoretical results.

  10. On The Convergence of Solutions of Globally Modified Navier-Stokes Equations with Delays To Solutions of Navier-Stokes Equations with Delays

    Marín Rubio, Pedro; Real Anguas, José; Márquez Durán, Antonio Miguel

    2011-01-01

    We prove that under suitable assumptions, from a sequence of solutions of globally modified Navier-Stokes equations with delays we can extract a subsequence which converges in an adequate sense to a weak solution of a three-dimensional Navier-Stokes equation with delays. An additional case with a family of different delays involved in the approximating problems is also discussed.

  11. Time-Delay Interferometry

    Dhurandhar Sanjeev V.

    2005-07-01

    Full Text Available Equal-arm interferometric detectors of gravitational radiation allow phase measurements many orders of magnitude below the intrinsic phase stability of the laser injecting light into their arms. This is because the noise in the laser light is common to both arms, experiencing exactly the same delay, and thus cancels when it is differenced at the photo detector. In this situation, much lower level secondary noises then set the overall performance. If, however, the two arms have different lengths (as will necessarily be the case with space-borne interferometers, the laser noise experiences different delays in the two arms and will hence not directly cancel at the detector. In order to solve this problem, a technique involving heterodyne interferometry with unequal arm lengths and independent phase-difference readouts has been proposed. It relies on properly time-shifting and linearly combining independent Doppler measurements, and for this reason it has been called Time-Delay Interferometry (TDI. This article provides an overview of the theory and mathematical foundations of TDI as it will be implemented by the forthcoming space-based interferometers such as the Laser Interferometer Space Antenna (LISA mission. We have purposely left out from this first version of our "Living Review" article on TDI all the results of more practical and experimental nature, as well as all the aspects of TDI that the data analysts will need to account for when analyzing the LISA TDI data combinations. Our forthcoming "second edition" of this review paper will include these topics.

  12. Concurrent Delay in Construction Disputes

    Cavaleri, Sylvie Cécile

    Delay is one of the issues most frequently encountered in today’s construction industry; it causes significant economic damage to all parties involved. Construction contracts, standard and bespoke, almost invariably consider delay from a perspective of single liability. If the event causing the...... period of delay can potentially be attributed to several events falling within both parties' spheres of responsibility, commonly termed concurrent delay, is rarely regulated in construction contracts in spite of its common occurrence. This book analyses both the theoretical foundations and the practical...... solutions to the issue of concurrent delay in a comparative perspective between common and civil law systems, with an emphasis on Danish and English law....

  13. Vehicle barrier with access delay

    Swahlan, David J; Wilke, Jason

    2013-09-03

    An access delay vehicle barrier for stopping unauthorized entry into secure areas by a vehicle ramming attack includes access delay features for preventing and/or delaying an adversary from defeating or compromising the barrier. A horizontally deployed barrier member can include an exterior steel casing, an interior steel reinforcing member and access delay members disposed within the casing and between the casing and the interior reinforcing member. Access delay members can include wooden structural lumber, concrete and/or polymeric members that in combination with the exterior casing and interior reinforcing member act cooperatively to impair an adversarial attach by thermal, mechanical and/or explosive tools.

  14. A unified approach for impulsive lag synchronization of chaotic systems with time delay

    In this paper, we propose a unified approach for impulsive lag-synchronization of a class of chaotic systems with time delay by employing the stability theory of impulsive delayed differential equations. Three well-known delayed chaotic systems are presented to illustrate our results. Also, the estimates of the stable regions for these systems are given, respectively

  15. Benefit achieved through determination of patient-specific, best scan delay after administration of contrast agent in cardiovascular CT examination

    A peripheral contrast bolus was administered intravenously in 138 consecutive patients to determine the time to maximum density in a left ventricular or aortic region of interest by electron beam CT. 20 EKG-triggered scans were acquired within 70 heartbeats. The deviation of the time to maximum density from a standard, fixed scan delay was determined. Results: Mean time to maximum density was 22 s, and the average deviation from that mean was 5 s. At an injection rate of 4 cc/s, this deviation implies that determining the individual scan delay from a test bolus injection may potentially save 20 cc contrast per patient. This amount of contrast agent, in turn, is required for the test bolus. Conclusion: Deriving the individual scan delay from test bolus kinetics may improve image contrast in cardiovascular CT studies without additional contrast expense. (orig.)

  16. Long delayed radio echoes

    This thesis describes an experimental program carried out at Stanford over a five-year period. The experiment involved transmitting a radio signal, and tape-recording the output of a receiver gang-tuned with the transmitter for the following 30 s interval. The tapes were later audited for possible LDE. Although none of the possible LDE received reproduces exactly the transmitted signal, many exhibit features that seem unlikely to have been generated except by an LDE mechanism. A mechanism for producing LDE has been studied which involves signal propagation in an electron plasma wave mode at very low group velocity. Modifications to the simplified theory leading to prediction of longer delays are discussed

  17. Location Estimation using Delayed Measurements

    Bak, Martin; Larsen, Thomas Dall; Nørgård, Peter Magnus;

    1998-01-01

    When combining data from various sensors it is vital to acknowledge possible measurement delays. Furthermore, the sensor fusion algorithm, often a Kalman filter, should be modified in order to handle the delay. The paper examines different possibilities for handling delays and applies a new techn...... technique to a sensor fusion system for estimating the location of an autonomous guided vehicle. The system fuses encoder and vision measurements in an extended Kalman filter. Results from experiments in a real environment are reported...

  18. Modeling delay in genetic networks: From delay birth-death processes to delay stochastic differential equations

    Gupta, Chinmaya; López, José Manuel; Azencott, Robert; Ott, William [Department of Mathematics, University of Houston, Houston, Texas 77004 (United States); Bennett, Matthew R. [Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77204, USA and Institute of Biosciences and Bioengineering, Rice University, Houston, Texas 77005 (United States); Josić, Krešimir [Department of Mathematics, University of Houston, Houston, Texas 77004 (United States); Department of Biology and Biochemistry, University of Houston, Houston, Texas 77204 (United States)

    2014-05-28

    Delay is an important and ubiquitous aspect of many biochemical processes. For example, delay plays a central role in the dynamics of genetic regulatory networks as it stems from the sequential assembly of first mRNA and then protein. Genetic regulatory networks are therefore frequently modeled as stochastic birth-death processes with delay. Here, we examine the relationship between delay birth-death processes and their appropriate approximating delay chemical Langevin equations. We prove a quantitative bound on the error between the pathwise realizations of these two processes. Our results hold for both fixed delay and distributed delay. Simulations demonstrate that the delay chemical Langevin approximation is accurate even at moderate system sizes. It captures dynamical features such as the oscillatory behavior in negative feedback circuits, cross-correlations between nodes in a network, and spatial and temporal information in two commonly studied motifs of metastability in biochemical systems. Overall, these results provide a foundation for using delay stochastic differential equations to approximate the dynamics of birth-death processes with delay.

  19. Development of an improved method for calculating the effective delayed neutron fraction of a core using a structure with only a few collapsed energy groups

    In this study, an improved method for calculating the effective delayed neutron fraction of a core with a few collapsed energy groups has been developed. To accurately calculate the effective delayed neutron fraction of a core using the conventional method, a structure with several energy groups is needed for the fast energy region in order to reflect the difference in the fission spectra for prompt fission neutrons and delayed neutrons. On the other hand, a structure with only a few energy groups is needed for the criticality evaluation. Thus, the calculation cost increases for the effective delayed neutron fraction calculations owing to the need for a large number of energy groups. To solve this problem, in the present study, the error mechanism for the effective delayed neutron fraction calculation using a structure with only a few energy groups was studied, and it was found that the error results from the collapse of the fission spectra after the cell calculations without adjoint flux weighting. In addition, an improved method for the collapse fission spectra with an adjoint flux obtained by one-point calculation was developed. Using the proposed method, the effective delayed neutron fraction can be estimated with sufficient accuracy using a structure consisting of only a few collapsed energy groups. This result will contribute to reducing the calculation cost and/or improving the accuracy of effective delayed neutron fraction calculations. (author)

  20. Post-CTS Delay Insertion

    Jianchao Lu; Baris Taskin

    2010-01-01

    A post-clock-tree-synthesis (post-CTS) optimization method is proposed that suggests delay insertion at the leaves of the clock tree in order to implement a limited version of clock skew scheduling. Delay insertion is limited on each clock tree branch simultaneous with a global monitoring of the total amount of delay insertion. The delay insertion for nonzero clock skew operation is performed only at the clock sinks in order to preserve the structure and the optimizations implemented in the c...

  1. Architectural Overview of Delay Tolerant Network.

    S.Fowjiya; A.Udhayachandrika; Dr.A.Kathirvel

    2013-01-01

    This paper discuss about the current design of the Delay/Disruption Tolerant Networking (DTN) Architecture and also deals with some open issues regarding the architecture. At present we had achieved some stability within the design, but somehow additional experience is required to understand the concept of long ongoing transmissions at long running operational environments as well as to know the architectural complexity.The parameters including congestion, routing scenarios, security, and tra...

  2. A new method for analyzing diagnostic delay in gynecological cancer

    Vandborg, Mai Partridge; Edwards, Kasper; Kragtrup, Jakob; Vedsted, Peter; Hansen, Dorte Gilså; Mogensen, Ole

    2011-01-01

    delay of 6 weeks or more before treatment for gynecological cancer at a specialized regional department (The Department of Gynecology and Obstetrics, Odense University Hospital, Denmark). Methods. Maps of existing processes were performed for each patient reflecting the patients’ pathway through the......Objective. To present a new methodology to illustrate, understand and measure delay in health care. The method is inspired by process mapping tools as analytical framework and demonstrates its usefulness for studying diagnostic delay in gynecological cancer. Sample. Six women with a diagnostic...... delay in the diagnostic process. Some important contributors to diagnostic delay in gynecological cancer were found: lack of cancer suspicion, competing diseases, negative test results, inexpedient referral patterns and referrals without cancer suspicion. Conclusion. Our results point out process...

  3. Management of delayed nuclear power plant projects

    According to the available information at the IAEA PRIS (Power Reactor Information System) at the end of 1998 there were more than 40 nuclear power plant projects with delays of five or more years with respect to the originally scheduled commercial operation. The degree of conformance with original construction schedules showed large variations due to several issues, including financial, economic and public opinion factors. Taking into account the number of projects with several years delay in their original schedules, it was considered useful to identify the subject areas where exchange of experience among Member States would be mutually beneficial in identification of problems and development of guidance for successful management of the completion of these delayed projects. A joint programme of the IAEA Departments of Nuclear Energy (Nuclear Power Engineering Section) and Technical Co-operation (Europe Section, with additional support from the Latin America and West Asia Sections) was set up during the period 1997-1998. The specific aim of the programme was to provide assistance in the management of delayed nuclear power plants regarding measures to maintain readiness for resuming the project implementation schedule when the conditions permit. The integration of IAEA interdepartmental resources enabled the participation of 53 experts from 14 Member States resulting in a wider exchange of experience and dissemination of guidance. Under the framework of the joint programme, senior managers directly responsible for delayed nuclear power plant projects identified several issues or problem areas that needed to be addressed and guidance on management be provided. A work plan for the development of several working documents, addressing the different issues, was established. Subsequently these documents were merged into a single one to produce the present publication. This publication provides information and practical examples on necessary management actions to preserve

  4. Delayed feedback induced multirhythmicity in the oscillatory electrodissolution of copper.

    Nagy, Timea; Verner, Erika; Gáspár, Vilmos; Kori, Hiroshi; Kiss, István Z

    2015-06-01

    Occurrence of bi- and trirhythmicities (coexistence of two or three stable limit cycles, respectively, with distinctly different periods) has been studied experimentally by applying delayed feedback control to the copper-phosphoric acid electrochemical system oscillating close to a Hopf bifurcation point under potentiostatic condition. The oscillating electrode potential is delayed by τ and the difference between the present and delayed values is fed back to the circuit potential with a feedback gain K. The experiments were performed by determining the period of current oscillations T as a function of (both increasing and decreasing) τ at several fixed values of K. With small delay times, the period exhibits a sinusoidal type dependence on τ. However, with relatively large delays (typically τ ≫ T) for each feedback gain K, there exists a critical delay τcrit above which birhythmicity emerges. The experiments show that for weak feedback, Kτcrit is approximately constant. At very large delays, the dynamics becomes even more complex, and trirhythmicity could be observed. Results of numerical simulations based on a general kinetic model for metal electrodissolution were consistent with the experimental observations. The experimental and numerical results are also interpreted by using a phase model; the model parameters can be obtained from experimental data measured at small delay times. Analytical solutions to the phase model quantitatively predict the parameter regions for the appearance of birhythmicity in the experiments, and explain the almost constant value of Kτcrit for weak feedback. PMID:26117133

  5. Delayed unlatching mechanism

    Bzorgi, Fariborz M.

    2015-05-19

    In various embodiments an apparatus is presented for securing a structure such as a door, window, hatch, or gate that moves between an open and a closed position relative to a fixed structure to provide or deny access to a compartment, a room, an outdoor area, or a facility. Various embodiments provide a delay in opening the closure of sufficient duration to frustrate a rapid activation that might be desired by a person who is attempting to pass through the closure for some illicit purpose. Typically, hydraulics are used to activate the apparatus and no electrical energy or electronic signals are employed. In one embodiment, a plurality of actuations of a hand lever operates a hydraulic pump that moves a locking bolt from a first position in which a locking bolt is engaged with a recess in the fixed structure (preventing opening of a gate) to a second position in which the locking bolt is disengaged from the recess to permit opening of the gate.

  6. Delay Adjusted Incidence Infographic

    This Infographic shows the National Cancer Institute SEER Incidence Trends. The graphs show the Average Annual Percent Change (AAPC) 2002-2011. For Men, Thyroid: 5.3*,Liver & IBD: 3.6*, Melanoma: 2.3*, Kidney: 2.0*, Myeloma: 1.9*, Pancreas: 1.2*, Leukemia: 0.9*, Oral Cavity: 0.5, Non-Hodgkin Lymphoma: 0.3*, Esophagus: -0.1, Brain & ONS: -0.2*, Bladder: -0.6*, All Sites: -1.1*, Stomach: -1.7*, Larynx: -1.9*, Prostate: -2.1*, Lung & Bronchus: -2.4*, and Colon & Rectum: -3/0*. For Women, Thyroid: 5.8*, Liver & IBD: 2.9*, Myeloma: 1.8*, Kidney: 1.6*, Melanoma: 1.5, Corpus & Uterus: 1.3*, Pancreas: 1.1*, Leukemia: 0.6*, Brain & ONS: 0, Non-Hodgkin Lymphoma: -0.1, All Sites: -0.1, Breast: -0.3, Stomach: -0.7*, Oral Cavity: -0.7*, Bladder: -0.9*, Ovary: -0.9*, Lung & Bronchus: -1.0*, Cervix: -2.4*, and Colon & Rectum: -2.7*. * AAPC is significantly different from zero (p<.05). Rates were adjusted for reporting delay in the registry. www.cancer.gov Source: Special section of the Annual Report to the Nation on the Status of Cancer, 1975-2011.

  7. Geometric time delay interferometry

    The space-based gravitational-wave observatory LISA, a NASA-ESA mission to be launched after 2012, will achieve its optimal sensitivity using time delay interferometry (TDI), a LISA-specific technique needed to cancel the otherwise overwhelming laser noise in the interspacecraft phase measurements. The TDI observables of the Michelson and Sagnac types have been interpreted physically as the virtual measurements of a synthesized interferometer. In this paper, I present Geometric TDI, a new and intuitive approach to extend this interpretation to all TDI observables. Unlike the standard algebraic formalism, Geometric TDI provides a combinatorial algorithm to explore exhaustively the space of second-generation TDI observables (i.e., those that cancel laser noise in LISA-like interferometers with time-dependent arm lengths). Using this algorithm, I survey the space of second-generation TDI observables of length (i.e., number of component phase measurements) up to 24, and I identify alternative, improved forms of the standard second-generation TDI observables. The alternative forms have improved high-frequency gravitational-wave sensitivity in realistic noise conditions (because they have fewer nulls in the gravitational-wave and noise response functions), and are less susceptible to instrumental gaps and glitches (because their component phase measurements span shorter time periods)

  8. Geometric Time Delay Interferometry

    Vallisneri, M

    2005-01-01

    The space-based gravitational-wave observatory LISA, a NASA--ESA mission to be launched after 2012, will achieve its optimal sensitivity using Time Delay Interferometry (TDI), a LISA-specific technique needed to cancel the otherwise overwhelming laser noise in the inter-spacecraft phase measurements. In this paper I present_Geometric TDI_, a new, intuitive approach to derive the TDI observables and to understand them as the virtual measurements of a synthesized multi-beam interferometer. Unlike the standard algebraic formalism, Geometric TDI provides a combinatorial algorithm to explore exhaustively the space of _second-generation_ TDI observables (i.e., those that cancel laser noise in LISA-like interferometers with time-dependent armlengths). Using this algorithm, I survey the space of second-generation TDI observables of length (i.e., number of component phase measurements) up to 24, and I identify alternative, improved forms of the standard second-generation TDI observables. The alternative forms have imp...

  9. Delayed breast implant reconstruction

    Hvilsom, Gitte B.; Hölmich, Lisbet R.; Steding-Jessen, Marianne;

    2012-01-01

    We evaluated the association between radiation therapy and severe capsular contracture or reoperation after 717 delayed breast implant reconstruction procedures (288 1- and 429 2-stage procedures) identified in the prospective database of the Danish Registry for Plastic Surgery of the Breast during...... the period between 1999 and 2006. A history of radiation therapy was associated with increased risk of severe capsular contracture for 1- and 2-stage procedures, with adjusted hazard ratios (HR) of 3.3 (95% confidence interval [CI]: 0.9-12.4) and 7.2 (95% CI: 2.4-21.4), respectively. Similarly, a...... history of radiation therapy was associated with a non-significantly increased risk of reoperation after both 1-stage (HR = 1.4; 95% CI: 0.7-2.5) and 2-stage (HR = 1.6; 95% CI: 0.9-3.1) procedures. Reconstruction failure was highest (13.2%) in the 2-stage procedures with a history of radiation therapy...

  10. Improving Accuracy in Arrhenius Models of Cell Death: Adding a Temperature-Dependent Time Delay.

    Pearce, John A

    2015-12-01

    The Arrhenius formulation for single-step irreversible unimolecular reactions has been used for many decades to describe the thermal damage and cell death processes. Arrhenius predictions are acceptably accurate for structural proteins, for some cell death assays, and for cell death at higher temperatures in most cell lines, above about 55 °C. However, in many cases--and particularly at hyperthermic temperatures, between about 43 and 55 °C--the particular intrinsic cell death or damage process under study exhibits a significant "shoulder" region that constant-rate Arrhenius models are unable to represent with acceptable accuracy. The primary limitation is that Arrhenius calculations always overestimate the cell death fraction, which leads to severely overoptimistic predictions of heating effectiveness in tumor treatment. Several more sophisticated mathematical model approaches have been suggested and show much-improved performance. But simpler models that have adequate accuracy would provide useful and practical alternatives to intricate biochemical analyses. Typical transient intrinsic cell death processes at hyperthermic temperatures consist of a slowly developing shoulder region followed by an essentially constant-rate region. The shoulder regions have been demonstrated to arise chiefly from complex functional protein signaling cascades that generate delays in the onset of the constant-rate region, but may involve heat shock protein activity as well. This paper shows that acceptably accurate and much-improved predictions in the simpler Arrhenius models can be obtained by adding a temperature-dependent time delay. Kinetic coefficients and the appropriate time delay are obtained from the constant-rate regions of the measured survival curves. The resulting predictions are seen to provide acceptably accurate results while not overestimating cell death. The method can be relatively easily incorporated into numerical models. Additionally, evidence is presented

  11. Denials and Delays of Radioactive Material Shipments

    delays of shipments of radioactive materials forms an important issue today. Radioactive materials need to be transported using all modes of transport for use in different applications such as public health, industry, research and production of nuclear power. The transport of radioactive materials is governed by national and international regulations, which are based on the International Atomic Energy Agency (IAEA) regulations for safe transport of radioactive materials (TS-R-1). These regulations ensure high standards of safety. Recently there were increasing numbers of instances of denials and delays of shipments of radioactive materials even when complying with the regulations. The denials and delays can result in difficulties to patients and others who rely on products sterilized by radiation. Therefore there is an urgent need for a universally accepted approach to solve this problem. In response, the IAEA has formed an International Steering Committee (ISC) on denials and delays of radioactive materials. Also, it designate the National Focal Points (NFP) representative to help the ISC members and the IAEA by informing about denial operations and how they can help. The Steering Committee developed and adopted an action plan which includes the action to be taken. This plan is based on: Awareness, Training, Communication, Lobbying for marketing, Economic and Harmonization among member states. It is important to work within the mandate of the ISC and in the line of action plan on denials and delays. It identified the following network members such as: National Focal Points, Regional Coordinators, National Committee, National Representative for different modes of transport and similar bodies, Carriers, Producers and Suppliers, Different civil societies, NGO's, Ministry of transport and others.

  12. #FakeNobelDelayReasons

    2013-01-01

    Tuesday’s hour-long delay of the Nobel Prize in Physics announcement was (and still is) quite the cause for speculation. But on the Twittersphere, it was simply the catalyst for some fantastic puns, so-bad-they're-good physics jokes and other shenanigans. Here are some of our favourite #FakeNobelDelayReasons.    

  13. Magnetic bearing optical delay line

    Dool, T.C. van den; Kamphues, F.G.; Fouss, B.; Henrioulle, K.; Hogenhuis, H.

    2004-01-01

    TNO TPD, in close cooperation with Micromega-Dynamics and Dutch Space, has developed an advanced Optical Delay Line (ODL) for use in PRIMA, GENIE and other ground based interferometers. The delay line design is modular and flexible, which makes scaling for other applications a relatively easy task.

  14. Consumer Procrastination and Purchase Delay

    Darpy, Denis

    2000-01-01

    Recent research on purchase delay have developed numerous situational and individual causes. This paper proposes Consumer Procrastination to conceptualize the individual factor which influence people to chronically delay their purchases. Consumer Procrastination is measured with a new scale. An experiment is designed to show the importance of its impact on the decision to not choose along with context effects.

  15. Delayed Reinforcement of Operant Behavior

    Lattal, Kennon A.

    2010-01-01

    The experimental analysis of delay of reinforcement is considered from the perspective of three questions that seem basic not only to understanding delay of reinforcement but also, by implication, the contributions of temporal relations between events to operant behavior. The first question is whether effects of the temporal relation between…

  16. Carbon monoxide-induced delayed amnesia, delayed neuronal death and change in acetylcholine concentration in mice

    Nabeshima, T.; Katoh, A.; Ishimaru, H.; Yoneda, Y.; Ogita, K.; Murase, K.; Ohtsuka, H.; Inari, K.; Fukuta, T.; Kameyama, T. (Meijo Univ., Nagoya (Japan))

    1991-01-01

    We investigated the interrelationship of delayed amnesia, delayed neuronal death and changes in acetylcholine concentration induced by carbon monoxide (CO)-exposure in mice. In the test for retention of the passive avoidance task, amnesia was observed 5 and 7 days after CO-exposure when the mice were exposed to CO 1 day after training; in the case when the mice were exposed to CO 5 and 7 days before training, amnesia was also observed in a retention test given 1 day after training. The number of pyramidal cells in the hippocampal CA1 subfield was lower than that of the control 3, 5 and 7 days after CO-exposure. But the neurodegeneration in the parietal cortex, area 1, was not observed until 7 days after CO-exposure. The findings indicated that the amnesia and the neuronal death were produced after a delay when the mice were exposed to CO. In addition, the delayed amnesia was closely related to the delayed neuronal death in the hippocampal CA1 subfield. Moreover, (3H)glutamate and (3H)glycine binding sites did not change after CO-exposure but, 7 days after CO-exposure, the concentration of acetylcholine and the binding of (3H)quinuclidinyl benzilate in the frontal cortex and the striatum were found to have significantly changed, but those in the hippocampus did not show significant change. Therefore, we suggest that delayed amnesia induced by CO-exposure may result from delayed neuronal death in the hippocampal CA1 subfield and dysfunction in the acetylcholinergic neurons, in the frontal cortex, the striatum and/or the hippocampus.

  17. Carbon monoxide-induced delayed amnesia, delayed neuronal death and change in acetylcholine concentration in mice

    We investigated the interrelationship of delayed amnesia, delayed neuronal death and changes in acetylcholine concentration induced by carbon monoxide (CO)-exposure in mice. In the test for retention of the passive avoidance task, amnesia was observed 5 and 7 days after CO-exposure when the mice were exposed to CO 1 day after training; in the case when the mice were exposed to CO 5 and 7 days before training, amnesia was also observed in a retention test given 1 day after training. The number of pyramidal cells in the hippocampal CA1 subfield was lower than that of the control 3, 5 and 7 days after CO-exposure. But the neurodegeneration in the parietal cortex, area 1, was not observed until 7 days after CO-exposure. The findings indicated that the amnesia and the neuronal death were produced after a delay when the mice were exposed to CO. In addition, the delayed amnesia was closely related to the delayed neuronal death in the hippocampal CA1 subfield. Moreover, [3H]glutamate and [3H]glycine binding sites did not change after CO-exposure but, 7 days after CO-exposure, the concentration of acetylcholine and the binding of [3H]quinuclidinyl benzilate in the frontal cortex and the striatum were found to have significantly changed, but those in the hippocampus did not show significant change. Therefore, we suggest that delayed amnesia induced by CO-exposure may result from delayed neuronal death in the hippocampal CA1 subfield and dysfunction in the acetylcholinergic neurons, in the frontal cortex, the striatum and/or the hippocampus

  18. A novel memristive time-delay chaotic system without equilibrium points

    Pham, V.-T.; Vaidyanathan, S.; Volos, C. K.; Jafari, S.; Kuznetsov, N. V.; Hoang, T. M.

    2016-02-01

    Memristor and time-delay are potential candidates for constructing new systems with complex dynamics and special features. A novel time-delay system with a presence of memristive device is proposed in this work. It is worth noting that this memristive time-delay system can generate chaotic attractors although it possesses no equilibrium points. In addition, a circuitry implementation of such time-delay system has been introduced to show its feasibility.

  19. Time-delay damping theory

    洪峰

    2002-01-01

    In this paper, existing damping theories are briefly reviewed. On the basis of the existing damping theories, a new kind of damping theory, i.e., the time-delay damping theory, is developed. In the time-delay damping theory, the damping force is considered to be directly proportional to the increment of displacement. The response analysis of an SDOF time-delay damping system is carried out, and the methods for obtaining the solution for a time-delay damping system in the time domain as well as the frequency domain are given. The comparison between results from different damping theories shows that the time-delay damping theory is both reasonable and convenient.

  20. Delayed failure of vanadium-hydrogen alloys

    Group Va refractory metals (Ta, V and Nb) are known to be embrittled in tension by hydrogen at low temperatures, but no work has been reported on delayed failure. The high mobility of hydrogen in V at room temperature, up to 5 x 10-5 cm2/sec, would be expected to enhance hydrogen migration to regions of high stress and affect time-dependent fracture behaviour. The present work was performed to determine the role of hydrogen, in solution and/or as a hydride, in the room temperature delayed failure behaviour of vanadium. Specimens were dead-weight loaded at room temperature in a creep-rupture testing machine; time to rupture was determined as a function of stress intensity, which was calculated by standard ASTM methods for a double edge notched sheet. Results are reported and discussed. (author)

  1. Modelling of time delay of electrical breakdown for nitrogen-filled tubes at pressures of 6.6 and 13.3 mbar in the increase region of the memory curve

    Experimentally measured electrical breakdown time delay data versus the afterglow period (representing 'memory curves') for nitrogen-filled tubes at pressures of 6.6 and 13.3 mbar have been shown. The influence of N(4S) nitrogen atoms on secondary electron emission from the cathode (the SEE process) in late afterglow has been discussed. N(4S) atom concentration decay over relaxation time τ, N(4S)(τ), has been analysed by a numerical model and two analytical models. N(4S) decay analytical models are combined with different yield models that describe the SEE process by N(4S) and these combinations are employed to fit the experimental data. It has been shown that in late afterglow solving of very simple analytical equations instead of numerical solving of partial differential equations for N(4S)(τ) fitting can be used and that the combination of the first and the second order of the SEE process by N(4S) in yield modelling should be used in the case of 13.3 mbar pressure.

  2. Group delay functions and its applications in speech technology

    Hema A Murthy; B Yegnanarayana

    2011-10-01

    Traditionally, the information in speech signals is represented in terms of features derived from short-time Fourier analysis. In this analysis the features extracted from the magnitude of the Fourier transform (FT) are considered, ignoring the phase component. Although the significance of the FT phase was highlighted in several studies over the recent three decades, the features of the FT phase were not exploited fully due to difficulty in computing the phase and also in processing the phase function. The information in the short-time FT phase function can be extracted by processing the derivative of the FT phase, i.e., the group delay function. In this paper, the properties of the group delay functions are reviewed, highlighting the importance of the FT phase for representing information in the speech signal. Methods to process the group delay function are discussed to capture the characteristics of the vocal-tract system in the form of formants or through a modified group delay function. Applications of group delay functions for speech processing are discussed in some detail. They include segmentation of speech into syllable boundaries, exploiting the additive and high resolution properties of the group delay functions. The effectiveness of segmentation of speech, and the features derived from the modified group delay are demonstrated in applications such as language identification, speech recognition and speaker recognition. The paper thus demonstrates the need to exploit the potential of the group delay functions for development of speech systems.

  3. Analysing End-to-End Packet Delay and Loss in mobile ad hoc networks for interactive audio applications

    Benaissa, Mouna; Lecuire, Vincent; Lepage, Francis; Schaff, André

    2003-01-01

    Interactive audio applications such as audio conferencing and telephony require high constraints on delay, jitter and loss. The packets of these applications must be received without significant loss, with low delay and jitter. When packet loss rate exceeds 10% and one way delay exceeds 150 ms, speech quality can be quite poor. Human conversation tolerates a maximum end-to-end delay of between 150 and 300 milliseconds. In addition, these packets must have a small delay variation to maintain c...

  4. Transport of radioactive materials by air: a national approach to cope with denials and delays

    Full text: Around 300 nuclear medicine services in the Greater Caribbean depend, almost exclusively, on the airlines to receive radiopharmaceuticals. Less than 20 % of the regional airlines accept radioactive materials in addition to delays and denials, altogether, result in hardships to patients undergoing diagnosis and treatment, despite compliance with regulations. In the international framework leaded by the IAEA to alleviate the difficulties encountered, national approaches are needed to support this effort. The paper presents the Cuban experience regarding statistics of denials and delays by air, generic examples and classification of causes. The role of a Facilitation Working Group and actions taken in communication, awareness, harmonization of regulations, education and training are discussed. The results show a sensitive improvement in the reported instances of denials and delays at domestic level, strongly influenced by the corporative social responsibility of the main national airline and the actions underway. On the other hand, the increasing number of reported denials by international airlines in the last two years, demonstrate how much work must be done at regional and international level. (author)

  5. Attosecond delays in molecular photoionization

    Huppert, Martin; Baykusheva, Denitsa; von Conta, Aaron; Wörner, Hans Jakob

    2016-01-01

    We report measurements of energy-dependent attosecond photoionization delays between the two outer-most valence shells of N$_2$O and H$_2$O. The combination of single-shot signal referencing with the use of different metal foils to filter the attosecond pulse train enables us to extract delays from congested spectra. Remarkably large delays up to 160 as are observed in N$_2$O, whereas the delays in H$_2$O are all smaller than 50 as in the photon-energy range of 20-40 eV. These results are interpreted by developing a theory of molecular photoionization delays. The long delays measured in N$_2$O are shown to reflect the population of molecular shape resonances that trap the photoelectron for a duration of up to $\\sim$110 as. The unstructured continua of H$_2$O result in much smaller delays at the same photon energies. Our experimental and theoretical methods make the study of molecular attosecond photoionization dynamics accessible.

  6. Delayed feedback control of unstable steady states in fractional-order chaotic systems

    Gjurchinovski, Aleksandar; Urumov, Viktor

    2010-01-01

    We study the possibility to stabilize unstable steady states in chaotic fractional-order dynamical systems by the time-delayed feedback method with both constant and time-varying delays. By performing a linear stability analysis in the constant delay case, we establish the parameter ranges for successful stabilization of unstable equilibria in the plane parametrizad by the feedback gain and the time delay. An insight into the control mechanism is gained by analyzing the characteristic equation of the controlled system, showing that the control scheme fails to control unstable equilibria having an odd number of positive real eigenvalues. It is shown numerically that delayed feedback control with a variable time-delay significantly enlarges the stability region of the steady states in comparison to the classical time-delayed feedback scheme with a constant delay.

  7. Dynamical behaviors in time-delay systems with delayed feedback and digitized coupling

    We consider a network of delay dynamical systems connected in a ring via unidirectional positive feedback with constant delay in coupling. For the specific case of Mackey–Glass systems on the ring topology, we capture the phenomena of amplitude death, isochronous synchronization and phase-flip bifurcation as the relevant parameters are tuned. Using linear stability analysis and Master Stability Function approach, we predict the region of amplitude death and synchronized states respectively in the parameter space and study the nature of transitions between the different states. For a large number of systems in the same dynamical configuration, we observe splay states, mixed splay states and phase locked clusters. We extend the study to the case of digitized coupling and observe that these emergent states still persist. However, the sampling and quantization reduce the regions of amplitude death and induce phase-flip bifurcation

  8. On Cucker-Smale model with noise and delay

    Erban, Radek; Haskovec, Jan; Sun, Yongzheng

    2015-01-01

    A generalization of the Cucker-Smale model for collective animal behaviour is investigated. The model is formulated as a system of delayed stochastic differential equations. It incorporates two additional processes which are present in animal decision making, but are often neglected in modelling: (i) stochasticity (imperfections) of individual behaviour; and (ii) delayed responses of individuals to signals in their environment. Sufficient conditions for flocking for the generalized Cucker-Sma...

  9. Time Delay in Molecular Photoionization

    Hockett, P; Villeneuve, D M; Corkum, P B

    2015-01-01

    Time-delays in the photoionization of molecules are investigated. As compared to atomic ionization, the time-delays expected from molecular ionization present a much richer phenomenon, with a strong spatial dependence due to the anisotropic nature of the molecular scattering potential. We investigate this from a scattering theory perspective, and make use of molecular photoionization calculations to examine this effect in representative homonuclear and hetronuclear diatomic molecules, nitrogen and carbon monoxide. We present energy and angle-resolved maps of the Wigner delay time for single-photon valence ionization, and discuss the possibilities for experimental measurements.

  10. Factors associated with patient and provider delays for tuberculosis diagnosis and treatment in Asia: a systematic review and meta-analysis.

    Jing Cai

    Full Text Available Delays in tuberculosis (TB diagnosis and treatment is a major barrier to effective management of the disease. Determining the factors associated with patient and provider delay of TB diagnosis and treatment in Asia may contribute to TB prevention and control.We searched the PubMed, EMBASE and Web of Science for studies that assessed factors associated with delays in care-seeking, diagnosis, or at the beginning of treatment, which were published from January 1992 to September 2014. Two reviewers independently identified studies that were related to our meta-analysis and extracted data from each study. Independent variables were categorized in separate tables for patient and provider delays.Among 45 eligible studies, 40 studies assessed patient delay whereas 30 assessed provider delay. Cross-sectional surveys were used in all but two articles, which included 17 countries and regions. Socio-demographic characteristics, TB-related symptoms and medical examination, and conditions of seeking medical care in TB patients were frequently reported. Male patients and long travel time/distance to the first healthcare provider led to both shorter patient delays [odds ratio (OR (95% confidence intervals, CI = 0.85 (0.78, 0.92; 1.39 (1.08, 1.78] and shorter provider delays [OR (95%CI = 0.96 (0.93, 1.00; 1.68 (1.12, 2.51]. Unemployment, low income, hemoptysis, and positive sputum smears were consistently associated with patient delay [ORs (95%CI = 1.18 (1.07, 1.30, 1.23 (1.02, 1.49, 0.64 (0.40, 1.00, 1.77 (1.07, 2.94, respectively]. Additionally, consultation at a public hospital was associated with provider delay [OR (95%CI = 0.43 (0.20, 0.91].We propose that the major opportunities to reduce delays involve enabling socio-demographic factors and medical conditions. Male, unemployed, rural residence, low income, hemoptysis, positive sputum smear, and long travel time/distance significantly correlated with patient delay. Male, long travel time/distance and

  11. Fundamentals of Delayed Coking Joint Industry Project

    Michael Volk; Keith Wisecarver

    2004-09-26

    Delayed coking evolved steadily over the early to mid 1900s to enable refiners to convert high boiling, residual petroleum fractions to light products such as gasoline. Pound for pound, coking is the most energy intensive of any operation in a modern refinery. Large amounts of energy are required to heat the thick, poor-quality petroleum residuum to the 900 to 950 degrees F required to crack the heavy hydrocarbon molecules into lighter, more valuable products. One common misconception of delayed coking is that the product coke is a disadvantage. Although coke is a low valued (near zero economic value) byproduct, compared to transportation fuels, there is a significant worldwide trade and demand for coke as it is an economical fuel. Coke production has increased steadily over the last ten years, with further increases forecast for the foreseeable future. Current domestic production is near 111,000 tons per day. A major driving force behind this increase is the steady decline in crude quality available to refiners. Crude slates are expected to grow heavier with higher sulfur contents while environmental restrictions are expected to significantly reduce the demand for high-sulfur residual fuel oil. Light sweet crudes will continue to be available and in even greater demand than they are today. Refiners will be faced with the choice of purchasing light sweet crudes at a premium price, or adding bottom of the barrel upgrading capability, through additional new investments, to reduce the production of high-sulfur residual fuel oil and increase the production of low-sulfur distillate fuels. A second disadvantage is that liquid products from cokers frequently are unstable, i.e., they rapidly form gum and sediments. Because of intermediate investment and operating costs, delayed coking has increased in popularity among refiners worldwide. Based on the 2000 Worldwide Refining Survey published in the Oil and Gas, the delayed coking capacity for 101 refineries around the world

  12. Fundamentals of Delayed Coking Joint Industry Project

    Michael Volk; Keith Wisecarver

    2003-09-26

    Delayed coking evolved steadily over the early to mid 1900s to enable refiners to convert high boiling, residual petroleum fractions to light products such as gasoline. Pound for pound, coking is the most energy intensive of any operation in a modern refinery. Large amounts of energy are required to heat the thick, poor-quality petroleum residuum to the 900 to 950 degrees F required to crack the heavy hydrocarbon molecules into lighter, more valuable products. One common misconception of delayed coking is that the product coke is a disadvantage. Although coke is a low valued (near zero economic value) byproduct, compared to transportation fuels, there is a significant worldwide trade and demand for coke as it is an economical fuel. Coke production has increased steadily over the last ten years, with further increases forecast for the foreseeable future. Current domestic production is near 111,000 tons per day. A major driving force behind this increase is the steady decline in crude quality available to refiners. Crude slates are expected to grow heavier with higher sulfur contents while environmental restrictions are expected to significantly reduce the demand for high-sulfur residual fuel oil. Light sweet crudes will continue to be available and in even greater demand than they are today. Refiners will be faced with the choice of purchasing light sweet crudes at a premium price, or adding bottom of the barrel upgrading capability, through additional new investments, to reduce the production of high-sulfur residual fuel oil and increase the production of low-sulfur distillate fuels. A second disadvantage is that liquid products from cokers frequently are unstable, i.e., they rapidly form gum and sediments. Because of intermediate investment and operating costs, delayed coking has increased in popularity among refiners worldwide. Based on the 2000 Worldwide Refining Survey published in the Oil and Gas, the delayed coking capacity for 101 refineries around the world

  13. Interaction of Airspace Partitions and Traffic Flow Management Delay

    Palopo, Kee; Chatterji, Gano B.; Lee, Hak-Tae

    2010-01-01

    To ensure that air traffic demand does not exceed airport and airspace capacities, traffic management restrictions, such as delaying aircraft on the ground, assigning them different routes and metering them in the airspace, are implemented. To reduce the delays resulting from these restrictions, revising the partitioning of airspace has been proposed to distribute capacity to yield a more efficient airspace configuration. The capacity of an airspace partition, commonly referred to as a sector, is limited by the number of flights that an air traffic controller can safely manage within the sector. Where viable, re-partitioning of the airspace distributes the flights over more efficient sectors and reduces individual sector demand. This increases the overall airspace efficiency, but requires additional resources in some sectors in terms of controllers and equipment, which is undesirable. This study examines the tradeoff of the number of sectors designed for a specified amount of traffic in a clear-weather day and the delays needed for accommodating the traffic demand. Results show that most of the delays are caused by airport arrival and departure capacity constraints. Some delays caused by airspace capacity constraints can be eliminated by re-partitioning the airspace. Analyses show that about 360 high-altitude sectors, which are approximately today s operational number of sectors of 373, are adequate for delays to be driven solely by airport capacity constraints for the current daily air traffic demand. For a marginal increase of 15 seconds of average delay, the number of sectors can be reduced to 283. In addition, simulations of traffic growths of 15% and 20% with forecasted airport capacities in the years 2018 and 2025 show that delays will continue to be governed by airport capacities. In clear-weather days, for small increases in traffic demand, increasing sector capacities will have almost no effect on delays.

  14. Impact of time-delayed feedback on spatiotemporal dynamics in the Lugiato-Lefever model

    Panajotov, K.; Puzyrev, D.; Vladimirov, A. G.; Gurevich, S. V.; Tlidi, M.

    2016-04-01

    We analyze the impact of delayed optical feedback (OF) on the spatiotemporal dynamics of the Lugiato-Lefever model. First, we carry out linear stability analysis and reveal the role of the OF strength and phase on the shape of the bistable curve as well as on Turing, Andronov-Hopf, and traveling-wave instability regions. Further, we demonstrate how the OF impacts the spatial dynamics by shifting the regions with different spatial eigenvalue spectra. In addition, we reveal a clustering behavior of cavity solitons as a function of the OF strength at fixed OF phase. Depending on the feedback parameters, OF can also induce a drift bifurcation of a stationary cavity soliton, as well as an Andronov-Hopf bifurcation of a drifting soliton. We present an analytical expression for the threshold of the drift bifurcation and show that above a certain value of the OF strength the system enters a region of spatiotemporal chaos.

  15. Delays and networked control systems

    Hetel, Laurentiu; Daafouz, Jamal; Johansson, Karl

    2016-01-01

    This edited monograph includes state-of-the-art contributions on continuous time dynamical networks with delays. The book is divided into four parts. The first part presents tools and methods for the analysis of time-delay systems with a particular attention on control problems of large scale or infinite-dimensional systems with delays. The second part of the book is dedicated to the use of time-delay models for the analysis and design of Networked Control Systems. The third part of the book focuses on the analysis and design of systems with asynchronous sampling intervals which occur in Networked Control Systems. The last part of the book exposes several contributions dealing with the design of cooperative control and observation laws for networked control systems. The target audience primarily comprises researchers and experts in the field of control theory, but the book may also be beneficial for graduate students. .

  16. Language Delays in Toddlers: Information for Parents

    ... Stages Listen Español Text Size Email Print Share Language Delays in Toddlers: Information for Parents Page Content ... situation or repeats scripts from TV Delays in language Delays in language are the most common types ...

  17. Tunable silicon CROW delay lines

    Morichetti, Francesco; Canciamilla, Antonio; Torregiani, Matteo; Ferrari, Carlo; Melloni, Andrea; Martinelli, Mario

    2010-05-01

    Tunable coupled resonator optical waveguides (CROWs) are powerful and versatile devices that can be used to dynamically control the delay of optical data streams on chip. In this contribution we show that CROW delay lines fabricated on a silicon on insulator (SOI) platform are suitable for applications in the emerging scenario of optical systems at 100 Gbit/s. Issues concerning technology, design, limits and applications of SOI CROWs are discussed. The performances of silicon CROW delay lines activated by thermal tuning are compared to those of glass CROW in terms of power consumption, thermal crosstalk and reconfiguration speed. The continuous delay of 10-ps long optical pulses by 8 bit length is demonstrated by using a silicon CROW with a bandwidth of 87 GHz and made of 12 RRs. At 100 Gbit/s this structure provides comparable figures of merit (fractional delay of 0.75 bit/RR and fractional loss of 0.7 dB per bit-delay) of state-of-the art glass CROW operating at 10 Gbit/s, yet the area of the latter being three order of magnitude larger. The compatibility of silicon CROW with the emerging 100 Gbit/s systems is demonstrated by showing error-free phase-preserving propagation of a 100 Gbit/s return-to-zero (RZ) polarization-division-multiplexing (PolDM) differential quaternary phase shit keying (DQPSK) signal dynamically delayed by the CROW. It is also demonstrated that a silicon CROW can be used in a PolDM system to introduce a polarization selective delay in order to optimize the time interleaving of the two orthogonally polarized data streams.

  18. Deconstructing delayed posttraumatic stress disorder

    Smid, G.E.

    2011-01-01

    According to the Diagnostic and Statistical Manual of Mental Disorders, delayed posttraumatic stress disorder (PTSD) must be diagnosed in individuals fulfilling criteria for PTSD if the onset of symptoms is at least six months after the trauma. The purpose of this thesis was to establish the prevalence of delayed PTSD and to examine factors that may explain its occurrence. We conducted a meta-analysis and examined prospective data from disaster survivors, unaccompanied refugee minors, and arm...

  19. Basin stability in delayed dynamics

    Leng, Siyang; Lin, Wei; Kurths, Jürgen

    2016-02-01

    Basin stability (BS) is a universal concept for complex systems studies, which focuses on the volume of the basin of attraction instead of the traditional linearization-based approach. It has a lot of applications in real-world systems especially in dynamical systems with a phenomenon of multi-stability, which is even more ubiquitous in delayed dynamics such as the firing neurons, the climatological processes, and the power grids. Due to the infinite dimensional property of the space for the initial values, how to properly define the basin’s volume for delayed dynamics remains a fundamental problem. We propose here a technique which projects the infinite dimensional initial state space to a finite-dimensional Euclidean space by expanding the initial function along with different orthogonal or nonorthogonal basis. A generalized concept of basin’s volume in delayed dynamics and a highly practicable calculating algorithm with a cross-validation procedure are provided to numerically estimate the basin of attraction in delayed dynamics. We show potential applicabilities of this approach by applying it to study several representative systems of biological or/and physical significance, including the delayed Hopfield neuronal model with multistability and delayed complex networks with synchronization dynamics.

  20. 具有时滞和自食的阶段结构的合作系统的周期解的研究%The study of Periodic Solution a Nonautonomous Stage-Structured System With Time Delay and Cannibalism Two Kinds of Additive Maps on Operator Algebras

    李秋英; 贾建文

    2006-01-01

    In this paper, we consider a cooperative model,which has a discrete delay, stage structure and cannibalism. By using the continuation theorem of coincidence degree theory, a sufficient condition is obtained for the existence of a positive periodic solution of this system.%本文讨论一类具有时滞、阶段结构及自食的非自治合作系统的动力学行为,利用重合度理论中的的连续性定理,得到系统正周期解存在的充分条件.

  1. Delay-coupled discrete maps: Synchronization, bistability, and quasiperiodicity

    The synchronization transition is studied in delay-coupled logistic maps. For low coupling, in-phase and out-of-phase synchronous dynamics coexist, and with increasing coupling there is a regime of quasiperiodicity before eventual attraction to a fixed point at a critical value of coupling that depends on the nonlinearity. The presence of a region of asynchrony separating two synchronized regimes-termed anomalous behaviour-has been observed earlier in continuous systems and is shown here to occur in delay mappings as well. There are regions of in-phase, anti-phase, and out-of-phase dynamics of periodic as well as chaotic attractors.

  2. Reaction diffusion equation with spatio-temporal delay

    Zhao, Zhihong; Rong, Erhua

    2014-07-01

    We investigate reaction-diffusion equation with spatio-temporal delays, the global existence, uniqueness and asymptotic behavior of solutions for which in relation to constant steady-state solution, included in the region of attraction of a stable steady solution. It is shown that if the delay reaction function satisfies some conditions and the system possesses a pair of upper and lower solutions then there exists a unique global solution. In terms of the maximal and minimal constant solutions of the corresponding steady-state problem, we get the asymptotic stability of reaction-diffusion equation with spatio-temporal delay. Applying this theory to Lotka-Volterra model with spatio-temporal delay, we get the global solution asymptotically tend to the steady-state problem's steady-state solution.

  3. CALIBRATION OF LOW-FREQUENCY, WIDE-FIELD RADIO INTERFEROMETERS USING DELAY/DELAY-RATE FILTERING

    We present a filtering technique that can be applied to individual baselines of wide-bandwidth, wide-field interferometric data to geometrically select regions on the celestial sphere that contain primary calibration sources. The technique relies on the Fourier transformation of wide-band frequency spectra from a given baseline to obtain one-dimensional 'delay images', and then the transformation of a time-series of delay images to obtain two-dimensional 'delay/delay-rate images'. Source selection is possible in these images given appropriate combinations of baseline, bandwidth, integration time, and source location. Strong and persistent radio frequency interference (RFI) limits the effectiveness of this source selection owing to the removal of data by RFI excision algorithms. A one-dimensional, complex CLEAN algorithm has been developed to compensate for RFI-excision effects. This approach allows CLEANed, source-isolated data to be used to isolate bandpass and primary beam gain functions. These techniques are applied to data from the Precision Array for Probing the Epoch of Reionization as a demonstration of their value in calibrating a new generation of low-frequency radio interferometers with wide relative bandwidths and large fields of view.

  4. Nursing diagnosis of delayed surgical recovery

    Rosimere Ferreira Santana

    2014-09-01

    Full Text Available The purpose of this study was to identify and analyze the nursing diagnosis of delayed surgical recovery, its defining characteristics and related factors according to NANDA-I taxonomy, through an integrative review. 34 articles were selected from MEDLINE, CINAHL, LILACS, and BDENF databases. In these, the delayed surgical recovery diagnosis was identified in a study. However, it was possible to identify the defining characteristics: difficulty to move about (36.4% which requires help to complete self-care (27.3% and the evidence of interrupted healing of the surgical site (27.3%. Additionally, the related factors were: pain (34.2%, postoperative surgical site infection (31.7%, postoperative expectations (31.7%, and obesity (2.4%. Other identified related factors were: advanced age (38.9%, diabetes mellitus (22.2% and nutritional deficiency (16.7%. In conclusion, the diagnosis deals with a phenomenon of nursing surgical practice, recommended for the monitoring and standardized documentation of complications that may delay recovery and hospital discharge.

  5. Effects of Delayed Second Cochlear Implant

    XIA Rui-ming; WU Xi-hong; JANG Zi-gang; JING Yuan-yuan; LIN Yun-juan; YU Li-sheng

    2006-01-01

    Objective Since Helms' successful bilateral cochlear implantation with good results in 1996, there have been increasing number of reports on bilateral cochlear implantation. Most second device have been implantated within one year after the first. Considering effects of long time auditory deprivation, it is not clear whether a delayed second cochlear implant serves to add additional benefits and how it may interact with central nervous system plasticity. Methods Three cases who received delayed second cochlear implants at People's Hospital of Peking University from 2002 to 2005 were reviewed. The interval between the first and second implants was longer than 2 years in all three patients. Sound perception, and unilateral/bilateral speech discrimination in quiet and noise were evaluated. In addition, GAP detection test was conducted in one patient. Results In one case,having both implants on provided improved performance compared to using only one implant both in quiet and noise. Presumably due to visual interference from lip-reading or short interval between second implant and testing,one patient showed no improvement from using the second implant either in quiet or noise, while the last case demonstrated additional benefits from the second implant only in quiet. In all three patients, performance in recognizing the four tones in Mandarin was superior over word recognition. Conclusions Considerable plasticity in the cerebral auditory center is preserved, despite long acoustic deprivation in some children who have received unilateral cochlear implant. Delayed second implants can result in significant improvements in some of these children. Visual interference from lip-reading may be an obstacle during retraining. The better recognition of tones in the Mandarin language may represent a different sound discrimination mechanism in the auditory system,although it may also be related to the signal processing mechanisms of the implant used (MED-EL COMBI 40+).

  6. Earth system commitments due to delayed mitigation

    Pfister, Patrik L.; Stocker, Thomas F.

    2016-01-01

    As long as global CO2 emissions continue to increase annually, long-term committed Earth system changes grow much faster than current observations. A novel metric linking this future growth to policy decisions today is the mitigation delay sensitivity (MDS), but MDS estimates for Earth system variables other than peak temperature (ΔT max) are missing. Using an Earth System Model of Intermediate Complexity, we show that the current emission increase rate causes a ΔT max increase roughly 3-7.5 times as fast as observed warming, and a millenial steric sea level rise (SSLR) 7-25 times as fast as observed SSLR, depending on the achievable rate of emission reductions after the peak of emissions. These ranges are only slightly affected by the uncertainty range in equilibrium climate sensitivity, which is included in the above values. The extent of ocean acidification at the end of the century is also strongly dependent on the starting time and rate of emission reductions. The preservable surface ocean area with sufficient aragonite supersaturation for coral reef growth is diminished globally at an MDS of roughly 25%-80% per decade. A near-complete loss of this area becomes unavoidable if mitigation is delayed for a few years to decades. Also with respect to aragonite, 12%-18% of the Southern Ocean surface become undersaturated per decade, if emission reductions are delayed beyond 2015-2040. We conclude that the consequences of delaying global emission reductions are much better captured if the MDS of relevant Earth system variables is communicated in addition to current trends and total projected future changes.

  7. Earth system commitments due to delayed mitigation

    As long as global CO2 emissions continue to increase annually, long-term committed Earth system changes grow much faster than current observations. A novel metric linking this future growth to policy decisions today is the mitigation delay sensitivity (MDS), but MDS estimates for Earth system variables other than peak temperature (ΔT max) are missing. Using an Earth System Model of Intermediate Complexity, we show that the current emission increase rate causes a ΔT max increase roughly 3–7.5 times as fast as observed warming, and a millenial steric sea level rise (SSLR) 7–25 times as fast as observed SSLR, depending on the achievable rate of emission reductions after the peak of emissions. These ranges are only slightly affected by the uncertainty range in equilibrium climate sensitivity, which is included in the above values. The extent of ocean acidification at the end of the century is also strongly dependent on the starting time and rate of emission reductions. The preservable surface ocean area with sufficient aragonite supersaturation for coral reef growth is diminished globally at an MDS of roughly 25%–80% per decade. A near-complete loss of this area becomes unavoidable if mitigation is delayed for a few years to decades. Also with respect to aragonite, 12%–18% of the Southern Ocean surface become undersaturated per decade, if emission reductions are delayed beyond 2015–2040. We conclude that the consequences of delaying global emission reductions are much better captured if the MDS of relevant Earth system variables is communicated in addition to current trends and total projected future changes. (letter)

  8. Regional nodal staging with 18F-FDG PET–CT in non-small cell lung cancer: Additional diagnostic value of CT attenuation and dual-time-point imaging

    Background: [Fluorine-18]-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET–CT) is widely performed in the regional nodal staging of non-small cell lung cancer (NSCLC). However, the uptake of 18F-FDG by tubercular granulomatous tissues may lead to false-positive diagnosis. This is of special concern in China, where tubercular granulomatous disease is epidemic. Herein, we evaluated the efficacy of an additional CT attenuation and a dual-time-point scan in determining the status of lymph nodes. Methods: Eighty NSCLC patients underwent curative surgical resection after 18F-FDG PET–CT and separate breath-hold CT examinations. The initial images were analyzed by two methods. In method 1, nodal status was determined by 18F-FDG uptake only. In Method 2, nodal status was determined by 18F-FDG uptake associated with CT attenuation. For dual-time-point imaging, the retention index (RI) of benign and malignant nodal groups with positive uptake in the initial scan was examined. Results: A total of 265 nodal groups were documented. On a per-nodal-group basis, the diagnostic sensitivity, specificity, and accuracy of Method 1 were 66.7%, 89.7%, and 85.3%, respectively, whereas those of Method 2 were 64.7%, 96.7%, and 90.6%, respectively. The improvement in diagnostic specificity and accuracy associated with the addition of CT attenuation in Method 2 as compared to Method 1 was statistically significant (p 0.05). Conclusion: 18F-FDG PET–CT has high diagnostic value for preoperative lymph-node (N) staging of NSCLC patients. We show that 18F-FDG uptake combined with CT attenuation improves the diagnostic specificity and accuracy of nodal diagnosis in NSCLC. For the lymph nodes with positive uptake in the initial scan, dual-time-point imaging has limited effect in differentiation.

  9. Delayed bedtimes and obsessive-compulsive symptoms.

    Coles, Meredith E; Schubert, Jessica R; Sharkey, Katherine M

    2012-10-01

    There is increasing recognition of an important interplay between psychiatric disorders and sleep. Clinical observations and several empirical studies have shown that later bedtimes are associated with obsessive-compulsive disorder (OCD). This study examined the relation of delayed bedtimes (DBs) and symptoms of OCD. Two hundred and sixty-six undergraduates completed a battery of questionnaires assessing sleep patterns, mood, and obsessive-compulsive (OC) symptoms. Results showed that participants with DBs reported increased rates of OC symptoms, as compared with non-DB participants. Further, this relation remained significant when controlling for negative affect. Additional work examining the interplay between sleep and OC symptoms is warranted. PMID:22946735

  10. Delay Independent Criterion for Multiple Time-delay Systems

    Chang, C. J.; Liu, K. F. R.; Yeh, K.; Chen, C. W.; Chung, P. Y.

    Based on the fuzzy Lyapunov method, this work addresses the stability conditions for nonlinear systems with multiple time delays to ensure the stability of building structure control systems. The delay independent conditions are derived via the traditional Lyapunov and fuzzy Lyapunov methods for multiple time-delay systems as approximated by the Tagagi-Sugeno (T-S) fuzzy model. The fuzzy Lyapunov function is defined as a fuzzy blending of quadratic Lyapunov functions. A parallel distributed compensation (PDC) scheme is utilized to construct a global fuzzy logic control (FLC) by blending all linear local state feedback controllers in the controller design procedure. Furthermore, the H infinity performance and robustness of the design for modeling errors also need to be considered in the stability conditions.

  11. Model Additional Protocol

    Since the end of the cold war a series of events has changed the circumstances and requirements of the safeguards system. The discovery of a clandestine nuclear weapons program in Iraq, the continuing difficulty in verifying the initial report of Democratic People's Republic of Korea upon entry into force of their safeguards agreement, and the decision of the South African Government to give up its nuclear weapons program and join the Treaty on the Non-Proliferation of Nuclear Weapons have all played a role in an ambitious effort by IAEA Member States and the Secretariat to strengthen the safeguards system. A major milestone in this effort was reached in May 1997 when the IAEA Board of Governors approved a Model Protocol Additional to Safeguards Agreements. The Model Additional Protocol was negotiated over a period of less than a year by an open-ended committee of the Board involving some 70 Member States and two regional inspectorates. The IAEA is now in the process of negotiating additional protocols, State by State, and implementing them. These additional protocols will provide the IAEA with rights of access to information about all activities related to the use of nuclear material in States with comprehensive safeguards agreements and greatly expanded physical access for IAEA inspectors to confirm or verify this information. In conjunction with this, the IAEA is working on the integration of these measures with those provided for in comprehensive safeguards agreements, with a view to maximizing the effectiveness and efficiency, within available resources, the implementation of safeguards. Details concerning the Model Additional Protocol are given. (author)

  12. Delayed Gastric Emptying after Living Donor Hepatectomy for Liver Transplantation

    Hanjay Wang

    2014-01-01

    Full Text Available Delayed gastric emptying is a significant postoperative complication of living donor hepatectomy for liver transplantation and may require endoscopic or surgical intervention in severe cases. Although the mechanism of posthepatectomy delayed gastric emptying remains unknown, vagal nerve injury during intraoperative dissection and adhesion formation postoperatively between the stomach and cut liver surface are possible explanations. Here, we present the first reported case of delayed gastric emptying following fully laparoscopic hepatectomy for living donor liver transplantation. Additionally, we also present a case in which symptoms developed after open right hepatectomy, but for which dissection for left hepatectomy was first performed. Through our experience and these two specific cases, we favor a neurovascular etiology for delayed gastric emptying after hepatectomy.

  13. Optimal state estimation over communication channels with random delays

    Mahmoud, Magdi S.

    2013-04-01

    This paper is concerned with the optimal estimation of linear systems over unreliable communication channels with random delays. The measurements are delivered without time stamp, and the probabilities of time delays are assumed to be known. Since the estimation is time-driven, the actual time delays are converted into virtual time delays among the formulation. The receiver of estimation node stores the sum of arrived measurements between two adjacent processing time instants and also counts the number of arrived measurements. The original linear system is modeled as an extended system with uncertain observation to capture the feature of communication, then the optimal estimation algorithm of systems with uncertain observations is proposed. Additionally, a numerical simulation is presented to show the performance of this work. © 2013 The Franklin Institute.

  14. Targeted resequencing of the pericentromere of chromosome 2 linked to constitutional delay of growth and puberty.

    Diana L Cousminer

    Full Text Available Constitutional delay of growth and puberty (CDGP is the most common cause of pubertal delay. CDGP is defined as the proportion of the normal population who experience pubertal onset at least 2 SD later than the population mean, representing 2.3% of all adolescents. While adolescents with CDGP spontaneously enter puberty, they are at risk for short stature, decreased bone mineral density, and psychosocial problems. Genetic factors contribute heavily to the timing of puberty, but the vast majority of CDGP cases remain biologically unexplained, and there is no definitive test to distinguish CDGP from pathological absence of puberty during adolescence. Recently, we published a study identifying significant linkage between a locus at the pericentromeric region of chromosome 2 (chr 2 and CDGP in Finnish families. To investigate this region for causal variation, we sequenced chr 2 between the genomic coordinates of 79-124 Mb (genome build GRCh37 in the proband and affected parent of the 13 families contributing most to this linkage signal. One gene, DNAH6, harbored 6 protein-altering low-frequency variants (< 6% in the Finnish population in 10 of the CDGP probands. We sequenced an additional 135 unrelated Finnish CDGP subjects and utilized the unique Sequencing Initiative Suomi (SISu population reference exome set to show that while 5 of these variants were present in the CDGP set, they were also present in the Finnish population at similar frequencies. Additional variants in the targeted region could not be prioritized for follow-up, possibly due to gaps in sequencing coverage or lack of functional knowledge of non-genic genomic regions. Thus, despite having a well-characterized sample collection from a genetically homogeneous population with a large population-based reference sequence dataset, we were unable to pinpoint variation in the linked region predisposing delayed puberty. This study highlights the difficulties of detecting genetic variants

  15. Dynamic Server Allocation over Time Varying Channels with Switchover Delay

    Celik, Güner D; Modiano, Eytan

    2012-01-01

    We consider a dynamic server allocation problem over parallel queues with randomly varying connectivity and server switchover delay between the queues. At each time slot the server decides either to stay with the current queue or switch to another queue based on the current connectivity and the queue length information. Switchover delay occurs in many telecommunications applications and is a new modeling component of this problem that has not been previously addressed. We show that the simultaneous presence of randomly varying connectivity and switchover delay changes the system stability region and the structure of optimal policies. In the first part of the paper, we consider a system of two parallel queues, and develop a novel approach to explicitly characterize the stability region of the system using state-action frequencies which are stationary solutions to a Markov Decision Process (MDP) formulation. We then develop a frame-based dynamic control (FBDC) policy, based on the state-action frequencies, and ...

  16. Importance of delayed neutron data in transmutation system

    The accelerator-driven transmutation system has been studied at the Japan Atomic Energy Research Institute. This system is a hybrid system which consists of a high intensity accelerator, a spallation target and a subcritical core region. The subcritical core is driven by neutrons generated by spallation reaction in the target region. There is no control rod in this system, so the power is controlled only by proton beam current. The beam current to keep constant power change with effective multiplication factor of subcritical core. So, the evaluation of delayed neutron fraction which is strongly connected to the measurement of subcritical level is important factor in operation of accelerator-driven system. In this paper, important nuclides for the delayed neutron fraction of ADS will be discussed, moreover, present state of delayed neutron data in evaluated nuclear data library is presented. (author)

  17. Geometric representation for numerical stability region of linear multistep methods

    2001-01-01

    Studies the numerical stability region of linear multistep(LM) methods applied to linear test equation of the formy′(t) = ay(t) + by( t - 1), t > 0, y( t ) = g( t ) - 1 ≤ t ≤ 0, a,b ∈ R, proves through delaydependent stability analysis that the intersection of stability regions of the equation and the method is not empty, in addition to approaches to the boundary of the delay differential equation(DDEs) in the limiting case of stepsize boundary of the stability region of linear multistep methods.

  18. 49 CFR 236.563 - Delay time.

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Delay time. 236.563 Section 236.563 Transportation... Cab Signal Systems Rules and Instructions; Locomotives § 236.563 Delay time. Delay time of automatic... requirements of § 236.24 shall take into consideration the delay time....

  19. On Stability of Linear Time-Delay Systems with Multiple Time-Varying Delays

    Park, Gwang-Seok; Choi, Ho-Lim

    In this letter, delay-dependent stability criterion for linear time-delay systems with multiple time varying delays is proposed by employing the Lyapunov-Krasovskii functional approach and integral inequality. By the N-segmentation of delay length, we obtain less conservative results on the delay bounds which guarantee the asymptotic stability of the linear time-delay systems with multiple time varying delays. Simulation results show that the proposed stability criteria are less conservative than several other existing criteria.

  20. Chaos in the delay logistic equation with discontinuous delays

    This paper analyzes a delay logistic equation which models a feedback control problem. Interval map associated to the system is derived. By calculating Lyapunov exponent, we indicate stable orbit and chaotic phenomenon respectively. The results are verified through computer simulation. We identify the parameter which controls the dynamics.

  1. A quantum delayed choice experiment

    Peruzzo A.; Shadbolt P.; Brunner N.; Popescu S.; O'Brien J.L.

    2012-01-01

    Quantum systems exhibit particle-like or wave-like behaviour depending on the experimental apparatus they are confronted by. This wave-particle duality is at the heart of quantum mechanics, and is fully captured in Wheeler's famous delayed choice gedanken experiment. In this variant of the double slit experiment, the observer chooses to test either the particle or wave nature of a photon after it has passed through the slits. Here we report on a quantum delayed choice experiment, based on a q...

  2. Importance of delayed neutrons in nuclear research

    The report presents a comprehensive review of the uses ofβ-, n delayed neutrons in nuclear research with special emphasis on energy spectra and reactor applications. The review covers the following aspects : (1) delayed neutron in reactor analysis, (2) absolute delayed neutron yield, (3) delayed neutron decay constants, (4) delayed neutron energy spectra and their importance in high accuracy criticality calculations and precise evaluation of reactor kinetics characteristics, particularly fast breeders, (5) a chronological account of the developments in the measurement of delayed neutron energy spectra, both aggregate (composite) and from individual fission product isotopes during the last fifty years or so, (6) major spectrometry techniques for measuring delayed neutron energy spectra, (7) spectral analysis, (8) calculations of delayed neutron energy spectra from precursor data, and (9) sensitivity analysis of fast reactor dynamic behaviour to delayed neutron energy spectra. Finally the report recommends a number of areas for future research work on delayed neutrons. (author). refs., 49 figs., 10 tabs

  3. Regional nodal staging with {sup 18}F-FDG PET-CT in non-small cell lung cancer: Additional diagnostic value of CT attenuation and dual-time-point imaging

    Li, Meng, E-mail: caseylimeng@126.com [Department of Diagnostic Radiology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021 (China); Wu, Ning, E-mail: cjr.wuning@vip.163.com [PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021 (China); Department of Diagnostic Radiology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021 (China); Liu, Ying, E-mail: liuyinggqw@sina.com [PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021 (China); Zheng, Rong, E-mail: zhengrong_2004@yahoo.com.cn [PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021 (China); Liang, Ying, E-mail: liangy_2000@sina.com [PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021 (China); Zhang, Wenjie, E-mail: winjiezh@163.com [PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021 (China); Zhao, Ping, E-mail: dr.zhaoping@263.net [PET-CT Center, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021 (China)

    2012-08-15

    Background: [Fluorine-18]-fluorodeoxyglucose positron emission tomography/computed tomography ({sup 18}F-FDG PET-CT) is widely performed in the regional nodal staging of non-small cell lung cancer (NSCLC). However, the uptake of {sup 18}F-FDG by tubercular granulomatous tissues may lead to false-positive diagnosis. This is of special concern in China, where tubercular granulomatous disease is epidemic. Herein, we evaluated the efficacy of an additional CT attenuation and a dual-time-point scan in determining the status of lymph nodes. Methods: Eighty NSCLC patients underwent curative surgical resection after {sup 18}F-FDG PET-CT and separate breath-hold CT examinations. The initial images were analyzed by two methods. In method 1, nodal status was determined by {sup 18}F-FDG uptake only. In Method 2, nodal status was determined by {sup 18}F-FDG uptake associated with CT attenuation. For dual-time-point imaging, the retention index (RI) of benign and malignant nodal groups with positive uptake in the initial scan was examined. Results: A total of 265 nodal groups were documented. On a per-nodal-group basis, the diagnostic sensitivity, specificity, and accuracy of Method 1 were 66.7%, 89.7%, and 85.3%, respectively, whereas those of Method 2 were 64.7%, 96.7%, and 90.6%, respectively. The improvement in diagnostic specificity and accuracy associated with the addition of CT attenuation in Method 2 as compared to Method 1 was statistically significant (p < 0.01). Thirty-nine nodal groups with positive uptake in the initial scan underwent dual-time-point imaging and the difference in the RI between benign and malignant groups showed no statistical significance (p > 0.05). Conclusion: {sup 18}F-FDG PET-CT has high diagnostic value for preoperative lymph-node (N) staging of NSCLC patients. We show that {sup 18}F-FDG uptake combined with CT attenuation improves the diagnostic specificity and accuracy of nodal diagnosis in NSCLC. For the lymph nodes with positive uptake in

  4. Delay oil oxidation during frying process

    Blend oil (mixed of refined sunflower and soy beans oils 1:1 w/w) containing add 200 ppm of rosemary leaves methanolic extract (rosemary extract) (RE) and 3% refined rice bran oil (RRBO), were used in frying process at 1800 degree c for 5 hrs/ day, four consecutive days to delay oil oxidation during frying. Therefore, rosemary extract (methanolic extract) was analyzed by HPLC technique for identification of flavonoids compounds (as a specific active compounds; gives high protection to frying oil). Physical and chemical properties, including refractive index(RI). Red color unit (R), viscosity, acidity (FFA), peroxide value (PV), iodine value (IV) oxidized fatty acid (OFA), polymer content (PC), total polar components (TPC) and trans fatty acid (TFA) as eliadic acid were determined. The results indicated that; rosemary extract contained about eight flavonoids compounds (hypersoid, rutin, 3-OH flavon, luleotin, kempferol, sakarutin, querectrin and apeginin). Addition of RE or RRBO to frying oil caused delay oil oxidation during frying process compared with frying oil without any addition. Also, the results indicated that rosemary extract was more effective in reducing formation of PV, FFA, OFA, PC, TPC and TFA in frying oil than refined rice bran oil

  5. Numerical simulation of time delays in light induced ionization

    Su, Jing; Becker, Andreas; Jaroń-Becker, Agnieszka

    2012-01-01

    We apply a fundamental definition of time delay, as the difference between the time a particle spends within a finite region of a potential and the time a free particle spends in the same region, to determine results for photoionization of an electron by an extreme ultraviolet (XUV) laser field using numerical simulations on a grid. Our numerical results are in good agreement with those of the Wigner-Smith time delay, obtained as the derivative of the phase shift of the scattering wave packet with respect to its energy, for the short-range Yukawa potential. In case of the Coulomb potential we obtain time delays for any finite region, while - as expected - the results do not converge as the size of the region increases towards infinity. The impact of an ultrashort near-infrared probe pulse on the time delay is analyzed for both the Yukawa as well as the Coulomb potential and is found to be small for intensities below $10^{13}$ W/cm$^2$.

  6. Drain Current Response Delay of FD-SOI MOSFETs in RF Operation

    Shimizu, Yoshiyuki; Kim, Gue Chol; Murakami, Bunsei; Ueda, Keisuke; Utsurogi, Yoshihiro; Cha, Sungwoo; Matsuoka, Toshimasa; Taniguchi, Kenji

    2004-01-01

    We investigated the frequency dependences of Y22 of FD-SOI MOSFETs, in which the drain current response delay is observed for the first time. Short channel FD-SOI devices operating in linear region show significant drain current response delay. It is confirmed that FD-SOI MOSFET's RF behavior can be well reproduced with the proposed model including the drain current response delay.

  7. Two vicious circles contributing to a diagnostic delay for tuberculosis patients in Arkhangelsk

    2014-01-01

    Setting: Delay in tuberculosis (TB) diagnosis increases the infectious pool in the community and the risk of development of resistance of mycobacteria, which results in an increased number of deaths. Objective: To describe patients’ and doctors’ perceptions of diagnostic delay in TB patients in the Arkhangelsk region and to develop a substantive model to better understand the mechanisms of how these delays are linked to each other. Design: A grounded theory approach was used to study the ph...

  8. Two vicious circles contributing to a diagnostic delay for tuberculosis patients in Arkhangelsk

    Kuznetsov, Vladimir N.; Grjibovski, Andrej M.; Andrej O. Mariandyshev; Johansson, Eva; Bjune, Gunnar A

    2014-01-01

    Setting: Delay in tuberculosis (TB) diagnosis increases the infectious pool in the community and the risk of development of resistance of mycobacteria, which results in an increased number of deaths.Objective: To describe patients’ and doctors’ perceptions of diagnostic delay in TB patients in the Arkhangelsk region and to develop a substantive model to better understand the mechanisms of how these delays are linked to each other.Design: A grounded theory approach was used to study the phenom...

  9. Stochastic Resonance of a Periodically Driven Bistable System with Two Different Kinds of Time Delays

    In this paper, we study the phenomenon of stochastic resonance (SR) in a periodically driven bistable system with correlations between multiplicative and additive white noise terms when there are two different kinds of time delays existed in the deterministic and fluctuating forces, respectively. Using the small time delay approximation and the theory of signal-to-noise ratio (SNR) in the adiabatic limit, the expression of SNR is obtained. The effects of the delay time τ in the deterministic force, and the delay time θ in the fluctuating force on SNR are discussed. Based on the numerical computation, it is found that: (i) There appears a reentrant transition between one peak and two peaks and then to one peak again in the curve of SNR when the value of the time delay θ is increased. (ii) SR can be realized by tuning the time delay τ or θ with fixed noise, i.e., delay-induced stochastic resonance (DSR) exists. (general)

  10. Local Effects of Delayed Food

    Davison, Michael; Baum, William M.

    2007-01-01

    Five pigeons were trained on a procedure in which seven concurrent variable-interval schedules arranged seven different food-rate ratios in random sequence in each session. Each of these components lasted for 10 response-produced food deliveries, and components were separated by 10-s blackouts. We varied delays to food (signaled by blackout)…