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Sample records for activity physical exertion

  1. Exercise, physical activity, and exertion over the business cycle.

    Colman, Gregory; Dave, Dhaval

    2013-09-01

    Shifts in time and income constraints over economic expansions and contractions would be expected to affect individuals' behaviors. We explore the impact of the business cycle on individuals' exercise, time use, and total physical exertion, utilizing information on 112,000 individual records from the 2003-2010 American Time Use Surveys. In doing so, we test a key causal link that has been hypothesized in the relation between unemployment and health, but not heretofore assessed. Using more precise measures of exercise (and other activities) than previous studies, we find that as work-time decreases during a recession, recreational exercise, TV-watching, sleeping, childcare, and housework increase. This, however, does not compensate for the decrease in work-related exertion due to job-loss, and total physical exertion declines. These effects are strongest among low-educated men, which is validating given that employment in the Great Recession has declined most within manufacturing, mining, and construction. We also find evidence of intra-household spillover effects, wherein individuals respond to shifts in spousal employment conditional on their own labor supply. The decrease in total physical activity during recessions is especially problematic for vulnerable populations concentrated in boom-and-bust industries, and may have longer-term effects on obesity and related health outcomes. PMID:23906116

  2. Sex differences in the intensity and qualitative dimensions of exertional dyspnea in physically active young adults.

    Cory, Julia M; Schaeffer, Michele R; Wilkie, Sabrina S; Ramsook, Andrew H; Puyat, Joseph H; Arbour, Brandon; Basran, Robbi; Lam, Michael; Les, Christian; MacDonald, Benjamin; Jensen, Dennis; Guenette, Jordan A

    2015-11-01

    Understanding sex differences in the qualitative dimensions of exertional dyspnea may provide insight into why women are more affected by this symptom than men. This study explored the evolution of the qualitative dimensions of dyspnea in 70 healthy, young, physically active adults (35 M and 35 F). Participants rated the intensity of their breathing discomfort (Borg 0-10 scale) and selected phrases that best described their breathing from a standardized list (work/effort, unsatisfied inspiration, and unsatisfied expiration) throughout each stage of a symptom-limited incremental-cycle exercise test. Following exercise, participants selected phrases that described their breathing at maximal exercise from a list of 15 standardized phrases. Intensity of breathing discomfort was significantly higher in women for a given ventilation, but differences disappeared when ventilation was expressed as a percentage of maximum voluntary ventilation. The dominant qualitative descriptor in both sexes throughout exercise was increased work/effort of breathing. At peak exercise, women were significantly more likely to select the following phrases: "my breathing feels shallow," "I cannot get enough air in," "I cannot take a deep breath in," and "my breath does not go in all the way." Women adopted a more rapid and shallow breathing pattern and had significantly higher end-inspiratory lung volumes relative to total lung capacity throughout exercise relative to men. These findings suggest that men and women do not differ in their perceived quality of dyspnea during submaximal exercise, but subjective differences appear at maximal exercise and may be related, at least in part, to underlying sex differences in breathing patterns and operating lung volumes during exercise. PMID:26338458

  3. Using Ratings of Perceived Exertion in Physical Education

    Lagally, Kristen M.

    2013-01-01

    Ratings of perceived exertion have been shown to be a valid method of monitoring physical activity intensity for both adults and children. As such, this subjective method may serve as an alternative to objective measurements for assessing students' performance on national standards 2 and 4. The OMNI-Child perceived exertion scales were…

  4. The Role of Exercise Self-Efficacy, Perceived Exertion, Event-Related Stress, and Demographic Factors in Predicting Physical Activity among College Freshmen

    Brannagan, Kim

    2011-01-01

    Objectives: The focus of this study was to examine the relationship among precursors to physical activity, including exercise self-efficacy, perceived exertion, stress, and demographic factors, among college students. Design: This study employed an associational design. Setting: The study population was college freshmen in southeast Louisiana who…

  5. Does mental exertion alter maximal muscle activation?

    Vianney Rozand; Benjamin Pageaux

    2014-01-01

    Mental exertion is known to impair endurance performance, but its effects on neuromuscular function remain unclear. The purpose of this study was to test the hypothesis that mental exertion reduces torque and muscle activation during intermittent maximal voluntary contractions of the knee extensors. Ten subjects performed in a randomized order three separate mental exertion conditions lasting 27 minutes each: i) high mental exertion (incongruent Stroop task), ii) moderate mental exertion (con...

  6. Does mental exertion alter maximal muscle activation?

    Rozand, Vianney; Pageaux, Benjamin; Marcora, Samuele M.; Papaxanthis, Charalambos; Lepers, Romuald

    2014-01-01

    Mental exertion is known to impair endurance performance, but its effects on neuromuscular function remain unclear. The purpose of this study was to test the hypothesis that mental exertion reduces torque and muscle activation during intermittent maximal voluntary contractions of the knee extensors. Ten subjects performed in a randomized order three separate mental exertion conditions lasting 27 min each: (i) high mental exertion (incongruent Stroop task), (ii) moderate mental exertion (congr...

  7. Playing in parallel: the effects of multiplayer modes in active video game on motivation and physical exertion.

    Peng, Wei; Crouse, Julia

    2013-06-01

    Although multiplayer modes are common among contemporary video games, the bulk of game research focuses on the single-player mode. To fill the gap in the literature, the current study investigated the effects of different multiplayer modes on enjoyment, future play motivation, and the actual physical activity intensity in an active video game. One hundred sixty-two participants participated in a one-factor between-subject laboratory experiment with three conditions: (a) single player: play against self pretest score; (b) cooperation with another player in the same physical space; (c) parallel competition with another player in separated physical spaces. We found that parallel competition in separate physical spaces was the optimal mode, since it resulted in both high enjoyment and future play motivation and high physical intensity. Implications for future research on multiplayer mode and play space as well as active video game-based physical activity interventions are discussed. PMID:23509986

  8. Effects of 0.5 - 2 Gy gamma-rays on physical activities and intellectual behavior in dogs and influence of physical exertion on clinical manifestation

    A comparison of 88 pre-radiation and 433 post-radiation determinations demonstrated that 0.5∼2.0 Gy gamma irradiated police dogs could keep a good condition in physical performances such as 100-metre dash with or without load and 1.5∼5 km long-distance running with a load of 1/5 body weight. No detectable change could be found in intellectual behavior including performances in response to vocal or gestural command, discrimination of metronomic frequencies, differentiation between handkerchiefs from different persons, trailing, guarding and memory in any one of these dogs. As compared with 6 police dogs and 3 mongrel dogs kept at rest after irradiation, 7 police dogs and 3 mongrel dogs and 3 mongrel dogs undergoing above mentioned physical exertion showed fewer and milder symptoms and higher white

  9. Effects of the workplace health promotion activities soccer and zumba on muscle pain, work ability and perceived physical exertion among female hospital employees

    Barene, Svein; Krustrup, Peter; Holtermann, Andreas

    2014-01-01

    Objectives: This 40-week workplace physical training RCT investigated the effect of soccer and Zumba, respectively, on muscle pain intensity and duration, work ability, and rating of perceived exertion (RPE) during work among female hospital employees. Methods: 107 hospital employees were cluster...

  10. Does heavy physical exertion trigger myocardial infarction?

    Hallqvist, J; Möller, J; Ahlbom, A; Diderichsen, Finn; Reuterwall, C; de Faire, U

    2000-01-01

    carried out with 699 myocardial infarction patients after onset of the disease. These cases represented 47 percent of all cases in the study base, and 70 percent of all nonfatal cases. The relative risk from vigorous exertion was 6.1 (95% confidence interval: 4.2, 9.0). The rate difference was 1.5 per...... socioeconomic status. Premonitory symptoms were common, and this implies risks of reverse causation bias and misclassification of case exposure information that require methodological consideration. Different techniques (the use of the usual-frequency type of control information, a pair-matched analysis, and a...... standard case-referent analysis) were applied to overcome the threat of misclassification of control exposure information. A case-crossover analysis in a random sample of healthy subjects resulted in a relative risk close to unity, as expected....

  11. Physical exertion and working efficiency of reforestation workers

    Kennedy Michael D

    2011-06-01

    Full Text Available Abstract Background The purpose of this study was to quantify the physical exertion during tree planting work and to examine the relationships between exertion, task efficiency, and productivity. Methods Heart rate (HR was monitored on 34 tree planters while they worked. HR data was collected for a complete working day on 19 subjects and for shorter periods of time on 15 subjects. Video of work tasks was recorded on 22 subjects (video was recorded on 7 of the subjects for whom HR was monitored through a full working day and analyzed for working pace and proportion of time spent on each task. Results HR during a full day (9.0 ± 1.2 hours of tree planting work was 115.2 ± 8.8 beats.min-1, and working HR was 128.2 ± 15.6 beats.min-1 for 82.5 ± 6.8% of the work day. Mean work pace was 452 ± 174 trees.h-1, and the proportion of time spent planting each tree was 53 ± 8% of the working time. Significant (P Conclusions Tree planters work at approximately 65% of age-predicted HRmax, and maintain HR at approximately 59% of HRmax throughout the entire working day. Productivity in these workers appears to be related to effort rather than to experience or task efficiency per se.

  12. Persulfate activation during exertion of total oxidant demand.

    Teel, Amy L; Elloy, Farah C; Watts, Richard J

    2016-09-01

    Total oxidant demand (TOD) is a parameter that is often measured during in situ chemical oxidation (ISCO) treatability studies. The importance of TOD is based on the concept that the oxidant demand created by soil organic matter and other reduced species must be overcome before contaminant oxidation can proceed. TOD testing was originally designed for permanganate ISCO, but has also recently been applied to activated persulfate ISCO. Recent studies have documented that phenoxides activate persulfate; because soil organic matter is rich in phenolic moieties, it may activate persulfate rather than simply exerting TOD. Therefore, the generation of reactive oxygen species was investigated in three soil horizons of varied soil organic carbon content over 5-day TOD testing. Hydroxyl radical may have been generated during TOD exertion, but was likely scavenged by soil organic matter. A high flux of reductants + nucleophiles (e.g. alkyl radicals + superoxide) was generated as TOD was exerted, resulting in the rapid destruction of the probe compound hexachloroethane and the common groundwater contaminant trichloroethylene (TCE). The results of this research document that, unlike permanganate TOD, contaminant destruction does occur as TOD is exerted in persulfate ISCO systems and is promoted by the activation of persulfate by soil organic matter. Future treatability studies for persulfate ISCO should consider contaminant destruction as TOD is exerted, and the potential for persulfate activation by soil organic matter. PMID:27269993

  13. Physical activity

    Physical activity -- which includes an active lifestyle and routine exercise -- plus eating well, is the best way to ... shortness of breath when you are active Build physical activity into your regular routine Simple lifestyle changes can ...

  14. Physical exercise at the workplace reduces perceived physical exertion during healthcare work

    Jakobsen, Markus Due; Sundstrup, Emil; Brandt, Mikkel;

    2015-01-01

    exercise may decrease physical exertion during work. This study investigates the effect of workplace-based versus home-based physical exercise on physical exertion during work (WRPE) among healthcare workers. METHODS: 200 female healthcare workers (age: 42.0, body mass index: 24.1, average pain intensity......: 3.1 on a scale of 0 to 10, average WRPE: 3.6 on a scale of 0 to 10) from 18 departments at three participating hospitals. Participants were randomly allocated at the cluster level to 10 weeks of: (1) workplace physical exercise (WORK) performed in groups during working hours for 5×10 minutes per...... week and up to five group-based coaching sessions on motivation for regular physical exercise, or (2) home-based physical exercise (HOME) performed during leisure time for 5×10 minutes per week. Physical exertion was assessed at baseline and at 10-week follow-up. RESULTS: 2.2 (SD: 1.1) and 1.0 (SD: 1...

  15. Physical activity

    ... this page: //medlineplus.gov/ency/article/001941.htm Physical activity To use the sharing features on this page, please enable JavaScript. Physical activity -- which includes an active lifestyle and routine exercise -- ...

  16. Physical Activity

    Andersen, Lars Bo; Anderssen, Sigmund Alfred; Wisløff, Ulrik;

    2014-01-01

    Andersen LB, Anderssen SA, Wisløff U, Hellénius M-L, Fogelholm M, Ekelund U. (Expert Group) Nordic Nutrition Recommendations 2012. Integrating nutrition and physical activity. Chapter: Physical Activity p. 195-217.Nordic Counsil of Ministers.......Andersen LB, Anderssen SA, Wisløff U, Hellénius M-L, Fogelholm M, Ekelund U. (Expert Group) Nordic Nutrition Recommendations 2012. Integrating nutrition and physical activity. Chapter: Physical Activity p. 195-217.Nordic Counsil of Ministers....

  17. Physics activities

    As we move into the 21st Century, nuclear technology is on the verge of rejuvenation in advanced Member States and of expansion in developing Member States. The principal responsibilities of the IAEA are transferring technologies, co-ordinating scientific research, managing specialized projects and maintaining analytical quality control. The IAEA physics activities provide assistance with nuclear instrumentation, promote more effective utilization of research reactors and accelerators, and facilitate global co-operation in nuclear fusion research. These activities will help Member States improve their standards of living through the benefits of nuclear technology. This booklet presents a brief profile on the physics activities and involvement in these fields of the Physics Section, IAEA

  18. Self-Reported Low Vitality, Poor Mental Health, and Low Dietary Restraint Are Associated with Overperception of Physical Exertion

    Hunter, Gary R.; Chandler-Laney, Paula C.; Brock, David W.; Gower, Barbara A; Alvarez, Jessica A.; Bush, Nikki C.

    2010-01-01

    Objective. We investigated whether perceived exertion, in comparison to the physiological response to exercise, was associated with self-reported vitality, mental health, and physical function during daily activities, or weight control behaviors. Design. Weight-reduced, formerly overweight women (n = 126, aged 22–46 years), completed health and dietary control questionnaires, and underwent a treadmill-walking task while heart rate, ventilation, respiratory exchange ratio, and ratings of perce...

  19. Prior physical exertion modulates allocentric distance perception: a demonstration of task-irrelevant cross-modal transfer

    Clark, E. V.; Ward, N.S.; Kuppuswamy, A.

    2016-01-01

    Physical exertion has been previously shown to influence distance perception in the egocentric framework. In this study, we show that physical exertion influences allocentric distance perception. Twenty healthy volunteers made allocentric line length estimates following varying levels of physical exertion. Each participant was presented with 30 different line lengths ranging from 1 to 12 cm, and each length was presented three times. Each line presentation was preceded by the participant exer...

  20. Persisting Effects of Concussion on Heart Rate Variability during Physical Exertion.

    Abaji, Joseph Patrick; Curnier, Daniel; Moore, Robert Davis; Ellemberg, Dave

    2016-05-01

    The purpose of this study was to evaluate cardiac autonomic modulation in university athletes during the post-acute to late phase (mean, 95 days ±63) of injury at rest and during physical exertion. We also sought to evaluate the effect of time since injury and number of injuries on heart rate variability (HRV). We hypothesized that physical exertion would reveal persisting modifications in HRV following a concussion. We included, in a cross-sectional design, athletes who sustained a concussion and matched controls. Concussions were identified by a medical doctor using established criteria. Twelve male concussed and 12 control athletes took part in the study. Control participants were teammates who were chosen to match the concussed athletes with regard to their height, weight, education, and age. The beat-to-beat electrocardiogram intervals of the participants were measured at rest and during physical exertion (isometric hand grip contraction; IHGC), which was sustained for 3 minutes at 30% of the participants' maximum. Linear and nonlinear parameters of HRV were calculated. The ratio between low and high frequency (LF/HF) bands was calculated to assess the sympathovagal balance. During the IHGC, but not at rest, concussed athletes presented significantly lower power in HF bands, leading to a significantly higher LF/HF ratio (p ≤ 0.05). Thus, asymptomatic athletes still may exhibit modifications in cardiac autonomic modulation weeks to months following injury. These modifications may only become apparent during physical exertion. Monitoring HRV may aid diagnosis and provide insight about safe return to play. PMID:26159461

  1. Interactive Effects of Physical and Mental Workload: A Study of Muscle Function, Capacity and Exertion Type

    Ranjana K Mehta

    2011-01-01

    Workers experience combined physical and mental demands in their daily jobs, yet the contribution of these concurrent demands in the development of work-related musculoskeletal disorders (WMSDs) is not clearly understood. There is a need to understand how concurrent demands interact with different work parameters, such as force levels, muscles employed, and types of exertion, to influence physiological responses. Furthermore, whether muscle capacity is altered with these concurrent demands ...

  2. Physical Activity (Exercise)

    ... Our ePublications > Physical activity (exercise) fact sheet ePublications Physical activity (exercise) fact sheet How can physical activity improve ... Have had recent hip surgery More information on physical activity (exercise) For more information about physical activity (exercise), ...

  3. Physical exertion in simple reaction time and continuous attention of sport participants.

    Tsorbatzoudis, H; Barkoukis, V; Danis, A; Grouios, G

    1998-04-01

    To investigate the effect of physical exertion on simple reaction time and continuous attention of sport participants, an experiment was conducted with 46 male university students and 12 male cyclists. The subjects were assigned to three experimental and two control groups. The subjects of the experimental groups were asked to perform, following a 5-min, period of warming up, a high intensity exercise protocol for 5 min., on a mechanically braked cycle ergometer (Group A) or a moderate intensity exercise protocol for 30 min, on the same cycle ergometer (Groups B and C). Shortly before and immediately after the physical exercise subjects of all groups were asked to perform a test of simple reaction time and continuous attention. The subjects of the control groups were asked to perform at rest both tests of the simple reaction time and the continuous attention twice, with a 10-min. and a 35-min. interval between the first and second attempts, respectively. The results did not support the notion that exercise of moderate or high intensity influences significantly the cognitive performance of aerobically trained or untrained subjects. The results are discussed in the light of the current research findings concerning exertion and human psychomotor performance. PMID:9638756

  4. The effects of physical exertion on decision-making performance of Australian football umpires.

    Paradis, Kasey; Larkin, Paul; O'Connor, Donna

    2016-08-01

    Decision-making is a key component of an umpire's in-game performance, with each decision potentially having a direct impact on the result of the game. Additionally, umpires have to be physically fit to ensure they keep up with the gameplay. While research has identified the decision-making demands and running demands of umpires separately, few have explored the relationship between them. The aim of this investigation was to examine the relationship between physical exertion and decision-making performance of Australian football umpires at the sub-elite and junior levels. A total of 18 Australian football umpires (sub-elite, n = 10; junior n = 8) performed 10 × 300 m runs, with each repetition immediately followed by a video-based decision-making test, then 1 min of recovery. A Mann-Whitney U assessment indicated a significant difference between the sub-elite and junior level umpires for decision-making accuracy (U = 13.00, z = -2.43, P = 0.016, r = -0.5). However, there was no significant difference in response time (U = 28.00, z = -1.07, P = 0.315, r = -0.25). The sub-elite umpires completed the running efforts in significantly less time than the junior umpires (P running times for either skill level (P > 0.05). This suggests decision-making performance may not be affected by physical exertion. Therefore, it may be suggested coaches of football umpires allocate more time to the decision-making development of their umpires instead of focusing largely on the physical fitness side, as is currently the trend. PMID:26654891

  5. Guide to Physical Activity

    ... Families ( We Can! ) Health Professional Resources Guide to Physical Activity Physical activity is an important part of your ... to injury. Examples of moderate-intensity amounts of physical activity Common Chores Washing and waxing a car for ...

  6. Physical Activity Assessment

    Current evidence convincingly indicates that physical activity reduces the risk of colon and breast cancer. Physical activity may also reduce risk of prostate cancer. Scientists are also evaluating potential relationships between physical activity and other cancers.

  7. Prior physical exertion modulates allocentric distance perception: a demonstration of task-irrelevant cross-modal transfer.

    Clark, Ella V; Ward, Nick S; Kuppuswamy, Annapoorna

    2016-08-01

    Physical exertion has been previously shown to influence distance perception in the egocentric framework. In this study, we show that physical exertion influences allocentric distance perception. Twenty healthy volunteers made allocentric line length estimates following varying levels of physical exertion. Each participant was presented with 30 different line lengths ranging from 1 to 12 cm, and each length was presented three times. Each line presentation was preceded by the participant exerting one of the following three levels of their maximal voluntary force (MVF): 20, 50, or 80 % MVF using their hand in the pinch force task. Psychometric curves were obtained for the lines perceived as 'long' following each of the three force levels. Lines that were perceived as 'short' following 20 and 50 % MVF were perceived as 'long' following 80 % MVF; that is, there was a significant leftward shift in the psychometric curve following 80 % MVF when compared to 20 and 50 % MVF. Here, we demonstrate that physical exertion influences perception of distances in the allocentric framework. We discuss our findings with respect to cross-modal interactions, fatigue physiology, peri- and extra-personal space interactions. PMID:27052884

  8. Validity of Borg Ratings of Perceived Exertion During Active Video Game Play

    Pollock, Brandon S; Jacob E. Barkley; POTENZINI, NICK; DESALVO, RENEE M.; BUSER, STACEY L.; OTTERSTETTER, RONALD; JUVANCIC-HELTZEL, JUDITH A.

    2013-01-01

    During physically interactive video game play (e.g., Nintendo Wii), users are exposed to potential distracters (e.g., video, music), which may decrease their ratings of perceived exertion (RPE) throughout game play. The purpose of this investigation was to determine the association between RPE scores and heart rate while playing the Nintendo Wii. Healthy adults (N = 13, 53.5 ± 5.4 years old) participated in two exercise sessions using the Nintendo Wii Fit Plus. During each session participant...

  9. Implicit theories about willpower predict the activation of a rest goal following self-control exertion.

    Job, Veronika; Bernecker, Katharina; Miketta, Stefanie; Friese, Malte

    2015-10-01

    Past research indicates that peoples' implicit theories about the nature of willpower moderate the ego-depletion effect. Only people who believe or were led to believe that willpower is a limited resource (limited-resource theory) showed lower self-control performance after an initial demanding task. As of yet, the underlying processes explaining this moderating effect by theories about willpower remain unknown. Here, we propose that the exertion of self-control activates the goal to preserve and replenish mental resources (rest goal) in people with a limited-resource theory. Five studies tested this hypothesis. In Study 1, individual differences in implicit theories about willpower predicted increased accessibility of a rest goal after self-control exertion. Furthermore, measured (Study 2) and manipulated (Study 3) willpower theories predicted an increased preference for rest-conducive objects. Finally, Studies 4 and 5 provide evidence that theories about willpower predict actual resting behavior: In Study 4, participants who held a limited-resource theory took a longer break following self-control exertion than participants with a nonlimited-resource theory. Longer resting time predicted decreased rest goal accessibility afterward. In Study 5, participants with an induced limited-resource theory sat longer on chairs in an ostensible product-testing task when they had engaged in a task requiring self-control beforehand. This research provides consistent support for a motivational shift toward rest after self-control exertion in people holding a limited-resource theory about willpower. PMID:26075793

  10. Activity limitation and exertional dyspnea in adult asthmatic patients: What do we know?

    Vermeulen, François; Garcia, Gilles; Ninane, Vincent; Laveneziana, Pierantonio

    2016-08-01

    Limitation of activity is the most cited symptom described by uncontrolled asthma patients. Assessment of activity limitation can be undertaken through several ways, more or less complex, subjective or objective. Yet little is known about the link between patients sensations and objective measurements. The present review reports the current knowledge regarding activity limitation and symptom perception (i.e., exertional dyspnea) in adult patients with asthma. This work is based on references indexed by PubMed, irrespective of the year of publication. Overall, patients with stable asthma do not have a more sedentary lifestyle than healthy subjects. However, during a cycle ergometric test, the maximal load is reduced when FEV1, FVC and muscle strengths are decreased. Additionally, during the six-minute walking test, mild asthma patients walk less than healthy subjects even if the minimal clinically important difference is not reached. The major complaint of asthma patients when exercising is dyspnea that is mainly related to the inspiratory effort and also to dynamic hyperinflation in some circumstances. Finally, the administration of bronchodilator does not improve the ventilatory pattern and the exercise capacity of asthma patients and little is known on its effect on exertional dyspnea. The present review allows to conclude that until now there is no gold standard test allowing the objective assessment of "activity limitation and exertional dyspnea" in asthma patients. PMID:27492522

  11. Physical Activity and Children

    ... Food and Beverage Toolkit The AHA's Recommendations for Physical Activity in Children Updated:Jul 21,2016 Click image ... Inactive children are likely to become inactive adults. Physical activity helps with: controlling weight reducing blood pressure raising ...

  12. Neuropathogenic Escherichia coli K1 does not exhibit proteolytic activities to exert its pathogenicity

    Iqbal, Junaid; Rajani, Mehak; Siddiqui, Ruqaiyyah; Khan, Naveed Ahmed

    2013-01-01

    Background Proteases are well-known virulence factors that promote survival, pathogenesis and immune evasion of many pathogens. Several lines of evidence suggest that the blood–brain barrier permeability is a prerequisite in microbial invasion of the central nervous system. Because proteases are frequently associated with vascular permeability by targeting junctional proteins, here it is hypothesized that neuropathogenic Escherichia coli K1 exhibit proteolytic activities to exert its pathogen...

  13. Core muscle activity, exercise preference, and perceived exertion during core exercise with elastic resistance versus machine

    Jonas Vinstrup; Emil Sundstrup; Mikkel Brandt; Jakobsen, Markus D.; Joaquin Calatayud; Andersen, Lars L.

    2015-01-01

    Objectives. To investigate core muscle activity, exercise preferences, and perceived exertion during two selected core exercises performed with elastic resistance versus a conventional training machine. Methods. 17 untrained men aged 26–67 years participated in surface electromyography (EMG) measurements of five core muscles during torso-twists performed from left to right with elastic resistance and in the machine, respectively. The order of the exercises was randomized and each exercise con...

  14. Perceived physical exertion during healthcare work and prognosis for recovery from long-term pain in different body regions: Prospective cohort study

    Andersen Lars L

    2012-12-01

    Full Text Available Abstract Background The prevalence of musculoskeletal pain is high among healthcare workers. Knowledge about risk factors at work is needed to efficiently target preventive strategies. This study estimates the prognosis for recovery from long-term musculoskeletal pain in different body regions among healthcare workers with different levels of perceived physical exertion during healthcare work. Methods Prospective cohort study among 4,977 Danish female healthcare workers responding to a baseline and follow-up questionnaire in 2005 and 2006, respectively. We defined long-term pain, short-term pain and pain-free as > 30, 1–30 and 0 days with pain during the last year, and included in the analyses only those with long-term pain at baseline in the low back (N=1,089, neck/shoulder (N=1,400 and knees (N = 579, respectively. Using cumulative logistic regression analysis, the prognosis for recovering from long-term pain at baseline to short-term pain or pain-free at follow-up in the respective body regions when experiencing moderate or light (reference: strenuous physical exertion during healthcare work was modeled. Results Among those with long-term pain at baseline 34% (low back, 29% (neck/shoulders, and 29% (knees recovered to short-term pain at follow-up and 7% (low back, 8% (neck/shoulders, and 17% (knees recovered to being pain-free. After adjusting for potential confounders (age, BMI, tenure, smoking status, leisure physical activity and psychosocial work conditions, light perceived physical exertion during healthcare work was associated with improved prognosis for recovery from long-term pain in the low back (OR 1.42, 95% CI 1.01 – 1.99 and neck/shoulders (OR 1.89, 95% CI 1.43 – 2.50, but not in the knees. Moderate physical exertion was not associated with improved prognosis for recovery from long-term pain for any of the body regions. Conclusion In the present study, healthcare workers with light perceived physical exertion during

  15. Preschoolers’ Physical Activity Behaviours

    Irwin, Jennifer D.; He, Meizi; Bouck, L. Michelle Sangster; Tucker, Patricia; Pollett, Graham L.

    2016-01-01

    Objectives To understand parents’ perspectives of their preschoolers’ physical activity behaviours. Methods A maximum variation sample of 71 parents explored their preschoolers’ physical activity behaviours through 10 semi-structured focus group discussions. Results Parents perceived Canada’s Physical Activity Guidelines for Children as inadequate; that their preschoolers get and need more than 30–90 minutes of activity daily; and that physical activity habits must be established during the preschool years. Nine barriers against and facilitators toward adequate physical activity were proposed: child’s age, weather, daycare, siblings, finances, time, society and safety, parents’ impact, and child’s activity preferences. Discussion The need for education and interventions that address current barriers are essential for establishing physical activity as a lifestyle behaviour during early childhood and, consequently, helping to prevent both childhood and adulthood obesity. PMID:16625802

  16. The Design of Networked Exertion Games

    Frank Vetere

    2009-01-01

    Full Text Available Incorporating physical activity and exertion into pervasive gaming applications can provide health and social benefits. Prior research has resulted in several prototypes of pervasive games that encourage exertion as interaction form; however, no detailed critical account of the various approaches exists. We focus on networked exertion games and detail some of our work while identifying the remaining issues towards providing a coherent framework. We outline common lessons learned and use them as the basis for generalizations for the design of networked exertion games. We propose possible directions of further investigation, hoping to provide guidance for future work to facilitate greater awareness and exposure of exertion games and their benefits.

  17. Expanding exertion gaming

    Marshall, Joe; Mueller, Florian ‘Floyd’; Benford, Steve; Pijnappel, Sebastiaan

    2016-01-01

    While exertion games - digital games where the outcome is determined by physical exertion - are of growing interest in HCI, we believe the current health and fitness focus in the research of exertion games limits the opportunities this field has to offer. In order to broaden the agenda on exertion games, we link the existing fields of sports and interactive entertainment (arguing these fields have much to offer) by presenting four of our own designs as case studies. Using our experiences with...

  18. Update: Exertional hyponatremia, active component, U.S. Army, Navy, Air Force, and Marine Corps, 2000-2015.

    2016-03-01

    From 2000 through 2015, there were 1,542 incident diagnoses of exertional hyponatremia among active component members of the U.S. Army, Navy, Air Force, and Marine Corps. Annual incidence rates rose sharply from 2008 through 2010 but then decreased by more than 50% from 2010 through 2013. In 2015, the number of cases (n=116) increased by approximately 20% from the previous year. The recent increase in rates overall reflects increased rates in the Army and the Marine Corps. Relative to their respective counterparts, crude incidence rates of exertional hyponatremia for the entire 16-year surveillance period were higher among females, those in the youngest age group, Marines, and recruit trainees. Service members (particularly recruit trainees) and their supervisors must be vigilant for early signs of heat-related illnesses and must be knowledgeable of the dangers of excessive water consumption and the prescribed limits for water intake during prolonged physical activity (e.g., field training exercises, personal fitness training, recreational activities) in hot, humid weather. PMID:27030930

  19. Activity Exerted by a Testosterone Derivative on Myocardial Injury Using an Ischemia/Reperfusion Model

    Figueroa-Valverde Lauro

    2014-01-01

    Full Text Available Some reports indicate that several steroid derivatives have activity at cardiovascular level; nevertheless, there is scarce information about the activity exerted by the testosterone derivatives on cardiac injury caused by ischemia/reperfusion (I/R. Analyzing these data, in this study, a new testosterone derivative was synthetized with the objective of evaluating its effect on myocardial injury using an ischemia/reperfusion model. In addition, perfusion pressure and coronary resistance were evaluated in isolated rat hearts using the Langendorff technique. Additionally, molecular mechanism involved in the activity exerted by the testosterone derivative on perfusion pressure and coronary resistance was evaluated by measuring left ventricular pressure in the absence or presence of the following compounds: flutamide, prazosin, metoprolol, nifedipine, indomethacin, and PINANE TXA2. The results showed that the testosterone derivative significantly increases P=0.05 the perfusion pressure and coronary resistance in isolated heart. Other data indicate that the testosterone derivative increases left ventricular pressure in a dose-dependent manner (0.001–100 nM; however, this phenomenon was significantly inhibited P=0.06 by indomethacin and PINANE-TXA2  P=0.05 at a dose of 1 nM. In conclusion, these data suggest that testosterone derivative induces changes in the left ventricular pressure levels through thromboxane receptor activation.

  20. Physical activity among adolescents

    Henriksen, P W; Ingholt, L; Rasmussen, M;

    2015-01-01

    The objectives of this study were (a) to examine the association between various kinds of parental social support and adolescents' physical activity (PA) and (b) to examine whether various kinds of social support from mothers and fathers were differently associated with boys' and girls' PA. Data...... understand why some adolescents are physically active and others are not....

  1. Peak Longevity Physical Activity

    People who engage in three to five times the recommended minimum level of leisure-time physical activity derive the greatest benefit in terms of mortality reduction when compared with people who do not engage in leisure-time physical activity.

  2. Correlates of physical activity

    Bauman, Adrian E; Reis, Rodrigo S; Sallis, James F;

    2012-01-01

    Physical inactivity is an important contributor to non-communicable diseases in countries of high income, and increasingly so in those of low and middle income. Understanding why people are physically active or inactive contributes to evidence-based planning of public health interventions, because...... that age, sex, health status, self-efficacy, and motivation are associated with physical activity. Ecological models take a broad view of health behaviour causation, with the social and physical environment included as contributors to physical inactivity, particularly those outside the health sector......, such as urban planning, transportation systems, and parks and trails. New areas of determinants research have identified genetic factors contributing to the propensity to be physically active, and evolutionary factors and obesity that might predispose to inactivity, and have explored the longitudinal...

  3. Physical Activity and Cancer

    ... of insulin and insulin-like growth factor I (IGF-I), improving the immune response ; and assisting with ... studies have started examining the factors related to long-term behavior change and increases in physical activity. ...

  4. Facts about Physical Activity

    ... stroke, type 2 diabetes, depression, and some cancers. Physical activity can also help with weight control, and may improve academic achievement in students. There's more . Inactive adults have a ...

  5. Physical activity: genes & health

    2002-01-01

    Carl Johan SUNDBERG is an Associate Professor in Physiology and Licenced Physician. His research focus is Molecular mechanisms involved in the adaptation of human skeletal muscle to physical activity.

  6. Novel small-molecule AMPK activator orally exerts beneficial effects on diabetic db/db mice

    Li, Yuan-Yuan; Yu, Li-Fang; Zhang, Li-Na; Qiu, Bei-Ying; Su, Ming-Bo; Wu, Fang; Chen, Da-Kai; Pang, Tao; Gu, Min; Zhang, Wei; Ma, Wei-Ping; Jiang, Hao-Wen; Li, Jing-Ya, E-mail: jyli@mail.shcnc.ac.cn; Nan, Fa-Jun, E-mail: fjnan@mail.shcnc.ac.cn; Li, Jia, E-mail: jli@mail.shcnc.ac.cn

    2013-12-01

    AMP-activated protein kinase (AMPK), which is a pivotal guardian of whole-body energy metabolism, has become an attractive therapeutic target for metabolic syndrome. Previously, using a homogeneous scintillation proximity assay, we identified the small-molecule AMPK activator C24 from an optimization based on the original allosteric activator PT1. In this paper, the AMPK activation mechanism of C24 and its potential beneficial effects on glucose and lipid metabolism on db/db mice were investigated. C24 allosterically stimulated inactive AMPK α subunit truncations and activated AMPK heterotrimers by antagonizing autoinhibition. In primary hepatocytes, C24 increased the phosphorylation of AMPK downstream target acetyl-CoA carboxylase dose-dependently without changing intracellular AMP/ATP ratio, indicating its allosteric activation in cells. Through activating AMPK, C24 decreased glucose output by down-regulating mRNA levels of phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G6Pase) in primary hepatocytes. C24 also decreased the triglyceride and cholesterol contents in HepG2 cells. Due to its improved bioavailability, chronic oral treatment with multiple doses of C24 significantly reduced blood glucose and lipid levels in plasma, and improved the glucose tolerance of diabetic db/db mice. The hepatic transcriptional levels of PEPCK and G6Pase were reduced. These results demonstrate that this orally effective activator of AMPK represents a novel approach to the treatment of metabolic syndrome. - Highlights: • C24 activates AMPK through antagonizing autoinhibition within α subunit. • C24 activates AMPK in hepatocytes and decreases glucose output via AMPK. • C24 exerts beneficial effects on diabetic db/db mice. • C24 represents a novel therapeutic for treatment of metabolic syndrome.

  7. Novel small-molecule AMPK activator orally exerts beneficial effects on diabetic db/db mice

    AMP-activated protein kinase (AMPK), which is a pivotal guardian of whole-body energy metabolism, has become an attractive therapeutic target for metabolic syndrome. Previously, using a homogeneous scintillation proximity assay, we identified the small-molecule AMPK activator C24 from an optimization based on the original allosteric activator PT1. In this paper, the AMPK activation mechanism of C24 and its potential beneficial effects on glucose and lipid metabolism on db/db mice were investigated. C24 allosterically stimulated inactive AMPK α subunit truncations and activated AMPK heterotrimers by antagonizing autoinhibition. In primary hepatocytes, C24 increased the phosphorylation of AMPK downstream target acetyl-CoA carboxylase dose-dependently without changing intracellular AMP/ATP ratio, indicating its allosteric activation in cells. Through activating AMPK, C24 decreased glucose output by down-regulating mRNA levels of phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G6Pase) in primary hepatocytes. C24 also decreased the triglyceride and cholesterol contents in HepG2 cells. Due to its improved bioavailability, chronic oral treatment with multiple doses of C24 significantly reduced blood glucose and lipid levels in plasma, and improved the glucose tolerance of diabetic db/db mice. The hepatic transcriptional levels of PEPCK and G6Pase were reduced. These results demonstrate that this orally effective activator of AMPK represents a novel approach to the treatment of metabolic syndrome. - Highlights: • C24 activates AMPK through antagonizing autoinhibition within α subunit. • C24 activates AMPK in hepatocytes and decreases glucose output via AMPK. • C24 exerts beneficial effects on diabetic db/db mice. • C24 represents a novel therapeutic for treatment of metabolic syndrome

  8. Visual complexity, player experience, performance and physical exertion in motion-based games for older adults

    Smeddinck, Jan D.; Gerling, Kathrin M.; Tiemkeo, Saranat

    2013-01-01

    Motion-based video games can have a variety of benefits for the players and are increasingly applied in physical therapy, rehabilitation and prevention for older adults. However, little is known about how this audience experiences playing such games, how the player experience affects the way older adults interact with motion-based games, and how this can relate to therapy goals. In our work, we decompose the player experience of older adults engaging with motion-based games, focusing on the e...

  9. Silybin-mediated inhibition of Notch signaling exerts antitumor activity in human hepatocellular carcinoma cells.

    Song Zhang

    Full Text Available Hepatocellular carcinoma (HCC is a global health burden that is associated with limited treatment options and poor patient prognoses. Silybin (SIL, an antioxidant derived from the milk thistle plant (Silybum marianum, has been reported to exert hepatoprotective and antitumorigenic effects both in vitro and in vivo. While SIL has been shown to have potent antitumor activity against various types of cancer, including HCC, the molecular mechanisms underlying the effects of SIL remain largely unknown. The Notch signaling pathway plays crucial roles in tumorigenesis and immune development. In the present study, we assessed the antitumor activity of SIL in human HCC HepG2 cells in vitro and in vivo and explored the roles of the Notch pathway and of the apoptosis-related signaling pathway on the activity of SIL. SIL treatment resulted in a dose- and time-dependent inhibition of HCC cell viability. Additionally, SIL exhibited strong antitumor activity, as evidenced not only by reductions in tumor cell adhesion, migration, intracellular glutathione (GSH levels and total antioxidant capability (T-AOC but also by increases in the apoptotic index, caspase3 activity, and reactive oxygen species (ROS. Furthermore, SIL treatment decreased the expression of the Notch1 intracellular domain (NICD, RBP-Jκ, and Hes1 proteins, upregulated the apoptosis pathway-related protein Bax, and downregulated Bcl2, survivin, and cyclin D1. Notch1 siRNA (in vitro or DAPT (a known Notch1 inhibitor, in vivo further enhanced the antitumor activity of SIL, and recombinant Jagged1 protein (a known Notch ligand in vitro attenuated the antitumor activity of SIL. Taken together, these data indicate that SIL is a potent inhibitor of HCC cell growth that targets the Notch signaling pathway and suggest that the inhibition of Notch signaling may be a novel therapeutic intervention for HCC.

  10. Global physical activity levels

    Hallal, Pedro C; Andersen, Lars Bo; Bull, Fiona C;

    2012-01-01

    To implement effective non-communicable disease prevention programmes, policy makers need data for physical activity levels and trends. In this report, we describe physical activity levels worldwide with data for adults (15 years or older) from 122 countries and for adolescents (13-15-years......-old) from 105 countries. Worldwide, 31·1% (95% CI 30·9-31·2) of adults are physically inactive, with proportions ranging from 17·0% (16·8-17·2) in southeast Asia to about 43% in the Americas and the eastern Mediterranean. Inactivity rises with age, is higher in women than in men, and is increased in high......-income countries. The proportion of 13-15-year-olds doing fewer than 60 min of physical activity of moderate to vigorous intensity per day is 80·3% (80·1-80·5); boys are more active than are girls. Continued improvement in monitoring of physical activity would help to guide development of policies and programmes...

  11. Phenolcarboxylic acids from medicinal herbs exert anticancer effects through disruption of COX-2 activity.

    Tao, Li; Wang, Sheng; Zhao, Yang; Sheng, Xiaobo; Wang, Aiyun; Zheng, Shizhong; Lu, Yin

    2014-09-25

    Integrated research of herbs and formulas characterized by functions of promoting blood circulation and removing blood stasis is one of the most active fields in traditional Chinese medicine. This paper strives to demonstrate the roles of a homologous series of phenolcarboxylic acids from these medicinal herbs in cancer treatment via targeting cyclooxygenase-2 (COX-2), a well-recognized mediator in tumorigenesis. We selected thirteen typical phenolcarboxylic acids (benzoic acid derivatives, cinnamic acid derivatives and their dehydration-condensation products), and found gallic acid, caffeic acid, danshensu, rosmarinic acid and salvianolic acid B showed 50% inhibitory effects on hCOX-2 activity and A549 cells proliferation. 2D-quantitative method was introduced to describe the potential structural features that contributed to certain bioactivities. We also found these compounds underwent responsible hydrogen bonding to Arg120 and Ser353 in COX-2 active site residues. We further extensively focused on danshensu [d-(+)-β-(3,4-dihydoxy-phenylalanine)] or DSS, which exerted COX-2 dependent anticancer manner. Both genetic and pharmacological inhibition of COX-2 could enhance the ability of DSS inhibiting A549 cells growth. Additionally, COX-2/PGE2/ERK signaling axis was essential for the anticancer effect of DSS. Furthermore, combined treatment with DSS and celecoxib could produce stronger anticancer effects in experimental lung metastasis of A549 cells in vivo. All these findings indicated that phenolcarboxylic acids might possess anticancer effects through jointly targeting COX-2 activity in cancer cells and provided strong evidence in cancer prevention and therapy for the herbs characterized by blood-activating and stasis-resolving functions in clinic. PMID:24916702

  12. Physical activity & depression

    Tsiantoula E.

    2012-07-01

    Full Text Available Depression is a major public health disorder. Clinical depression is the most frequent disability in North America among other countries and by 2020 it is estimated that it will represent the second most common disability worldwide. Physical activity can be used to prevent as well as treat depression. Its characteristics and structure should be individualized to the personality and special needs of the patient as well as to the severity of the disorder. Intensity, duration and the place of performance are of special importance. Research has identified neurobiological and psychological paths that can develop between physical activity and well being. More studies although are needed in order to standardize the use of physical activity as a treatment option, mainly in the groups of children and teenagers.

  13. Muscle activation, blood lactate, and perceived exertion responses to changing resistance training programming variables.

    Hiscock, Daniel J; Dawson, Brian; Donnelly, Cyril J; Peeling, Peter

    2016-08-01

    Ratings of perceived exertion (RPE: 0-10) during resistance training with varying programming demands were examined. Blood lactate (BLa) and muscle activation (using surface electromyography: EMG) were measured as potential mediators of RPE responses. Participants performed three sets of single arm (preferred side) bicep curls at 70% of 1 repetition maximum over 4 trials: Trial (A) 3 sets × 8 repetitions × 120 s recovery between sets; (B) 3 sets × 8 repetitions × 240 s recovery; (C) 3 sets × maximum number of repetitions (MNR) × 120 s recovery; (D) 3 sets × MNR × 240 s recovery. Overall body (RPE-O) and active muscle (RPE-AM) perceptual responses were assessed following each set in each trial. Biceps brachii and brachioradialis muscle EMG was measured during each set for each trial. RPE-O and RPE-AM were not different between Trial A (3.5 ± 1 and 6 ± 1, respectively) and Trial B (3.5 ± 1 and 5.5 ± 1, respectively) (p < .05). However, RPE-AM was significantly greater in Trial C (7.5 ± 1.5) and Trial D (7.5 ± 1.5) than in Trial B (p < .05). There were no significant differences in muscle activation or BLa between trials; however, work rate (tonnage/min) was greater in Trials C and D compared to Trial B. In conclusion, BLa and muscle activation were not related to RPE, but resistance training variables, such as work rate, may impact on RPE when intensity (%1RM) and the number of sets completed remain constant. PMID:26267339

  14. Light-activated nanofibre textiles exert antibacterial effects in the setting of chronic wound healing

    Arenbergerová, M.; Arenberger, P.; Bednář, M.; Kubát, Pavel; Mosinger, Jiří

    2012-01-01

    Roč. 21, č. 8 (2012), s. 619-624. ISSN 0906-6705 R&D Projects: GA ČR GAP208/11/2222 Institutional support: RVO:61388955 ; RVO:61388980 Keywords : antibacterial * leg ulcer * light-activated nanofibres Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.578, year: 2012

  15. Exercise and Physical Activity

    ... Make sure he or she drinks water or juice after exercise. For more information about exercise and physical activity for older adults, visit www.nia.nih.gov/Go4Life . National Institute on Aging National Institutes of Health NIH...Turning Discovery into Health Gentle Exercise Some ...

  16. Doxycycline exerted neuroprotective activity by enhancing the activation of neuropeptide GPCR PAC1.

    Yu, Rongjie; Zheng, Lijun; Cui, Yue; Zhang, Huahua; Ye, Heng

    2016-04-01

    Doxycycline has significant neuroprotective effect with anti-inflammatory and anti-apoptotic activity. We found for the first time that doxycycline specially promoted the proliferation of Chinese hamster ovary (CHO) cells with high expression of neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) preferring G protein-coupled receptor (GPCR), PACAP receptor 1(PAC1) and induced the internalization of PAC1 tagged with yellow fluorescent protein (YFP) indicating doxycycline interacted with PAC1. The homology modeling of PAC1 and molecular docking of doxycycline with PAC1 showed the theoretical binding of doxycycline to PAC1 at the site where PACAP(30-37) recognized. The competition binding assay and PAC1 site-specific mutation of Asp116, which formed two hydrogen bonds with Dox, confirmed the binding of doxycycline to PAC1 imitating PACAP(30-37). Doxycycline (100 ng/mL) significantly promoted the proliferative activities of vasoactive intestinal polypeptide (VIP) and oligopeptide HSDGIF responsible for the activation of PAC1 in PAC1-CHO cells, indicating that doxycycline facilitated the binding and the activation of PAC1 imitating PACAP(28-38). In Neuro2a cells with endogenous expression of PAC1 and its ligands, doxycycline not only promoted the proliferation of Neuro2a cells but also protected the cells from scopolamine induced apoptosis, which was inhibited by cAMP-PKA signal pathway inhibitor H-89, PAC1 shRNA or PACAP antagonist PACAP(6-38). The in vivo study showed long-term treatment with doxycycline (100ug/kg) had significant effect against scopolamine induced amnesia, and the synergetic anti-apoptotic, anti-oxidative and neuroprotective effect of doxycycline with VIP was more efficient than doxycycline alone or VIP alone, indicating doxycycline enhanced the activation of PAC1 in vivo effectively. Furthermore, doxycycline analogue minocycline also had similar theoretically binding site on PAC1 to doxycycline and displayed corresponding

  17. [Primary prevention: physical activity].

    Schuler, G

    2004-01-01

    Traditional risk factors such as smoking, hypertension and being overweight have received considerable attention in recent years, whereas physical activity as a preventive strategy does not enjoy the same public attention. In recent years the level of physical activity has decreased dramatically in children and adolescents in favor of time spent on the internet and in front of the TV. If this trend is allowed to develop along the same direction, a sharp increase in cardiovascular disease can be anticipated. The protective action of physical activity on the cardiovascular system has been well documented in large numbers of patients, and the basic physiological mechanisms have been elucidated. Metabolic changes comprise loss of weight, reduction in triglyceride and LDL levels, as well as an increase in HDL. Insulin sensitivity is enhanced in all tissues postponing the manifestation of diabetes mellitus. Shear forces created by physical activity induce ecNOS within the endothelial lining of the arteries. This enzyme is responsible for controlling vasomotion through the elaboration of NO which causes vasodilation in the smooth muscle within the vessel wall. Utilization of preformed collateral vessels has been postulated repeatedly; so far, however, it only could be documented in animals, not in humans. Nearly all studies concerned with primary prevention have shown a significant negative correlation between energy expenditure during exercise and cardiovascular mortality, even light and moderate exercise will result in a lower incidence. In order to eliminate a sedentary life style in children and adolescents, adequate programs should be initiated in all schools; they should aim for 60 min of physical activity on a daily basis. PMID:15021990

  18. Physical activation of molecules

    A brief review of processes of physical activation of molecules on the basis of phenomena of electronic and vibrational excitation, electron polarization is presented. Consideration is given to activation by electron impact, photo-, magneto- and mechanoactivation, as well as to radiation activation, proceeding under the effect of high-power radiations (102-107 eV). The character of disturbance of molecules, participating in chemical reactions, under the effect of different types of ionizing radiation (α-particles, electrons, γ-quanta etc.) is discussed

  19. Physical activity in elderly

    Jan Cvecka

    2015-08-01

    Full Text Available Aging is a multifactorial irreversible process associated with significant decline in muscle mass and neuromuscular functions. One of the most efficient methods to counteract age-related changes in muscle mass and function is physical exercise. An alternative effective intervention to improve muscle structure and performance is electrical stimulation. In the present work we present the positive effects of physical activity in elderly and a study where the effects of a 8-week period of functional electrical stimulation and strength training with proprioceptive stimulation in elderly are compared.

  20. Physical activity & depression

    Tsiantoula E.; Tsiadoula L.; Patsiaouras A.; Kokaridas D.

    2012-01-01

    Depression is a major public health disorder. Clinical depression is the most frequent disability in North America among other countries and by 2020 it is estimated that it will represent the second most common disability worldwide. Physical activity can be used to prevent as well as treat depression. Its characteristics and structure should be individualized to the personality and special needs of the patient as well as to the severity of the disorder. Intensity, duration and the place of pe...

  1. Changes in uridylic nucleotides and glycogen amount in animals tissue at exposure to ionizing radiation and physical exertion and some ways of their correction

    We have studied the amount of uridylic nucleoside phosphates and glycogen in the tissues of the rats exposed to ionizing radiation (6 Gy) and maximum physical exertion (running along a tredbahn till complete exhaustion). It has been shown that the amount of glycogen in the skeletal muscles decreases considerably 1 hour after combined action of ionizing radiation and physical exertion, 1 - 3 days after it decreased in the liver. Decrease of uridine diphosphate and uridine triphosphate polyphosphates amount as well as increase of uridine monophosphate in the tissue of the brain and liver are natural for uridylic nucleotides after combined action of ionizing radiation and physical exertion. These changes are more marked with increase of the period after the exposure

  2. Gene-physical activity interactions and their impact on diabetes

    Oskari Kilpeläinen, Tuomas; Franks, Paul W

    2014-01-01

    Physical activity exerts beneficial effects on glucose homeostasis that are channeled through our genes. Where variation in the target genes of physical activity exists, gene-physical activity interactions may occur, such that individual genetic profiles inflict differing physiological responses to...... an equal bout of physical activity. Individuals with specific genetic profiles are also expected to be more responsive to the beneficial effects of physical activity in the prevention of type 2 diabetes. Identification of such gene-physical activity interactions could give new insights into the...... introduce the reader to the recent advances in the genetics of type 2 diabetes, summarize the current evidence on gene-physical activity interactions in relation to type 2 diabetes, and outline how information on gene-physical activity interactions might help improve the prevention and treatment of type 2...

  3. Asthma and physical activity.

    Oseid, S

    1982-01-01

    Physical activity regularly leads to a decline in lung function in children and adolescents with asthma. This decline is a consequence of what is known as exercise-induced asthma (EIA), and can be determined and graded with the help of lung function tests before and after submaximal workloads on the ergometer cycle or the treadmill. Typical EIA appears in asthmatic individuals with entirely normal lung function before the effort, but EIA may also become clinically manifest with exercise in patients who have a subclinical degree of obstruction. The grade of EIA is essentially dependent on the duration and intensity of effort but also on the type of exercise. For example, free running causes much greater bronchoconstriction than swimming. The temperature and humidity of the inspired air may partially explain this difference. At the Voksentoppen Allergy Institute we find that about 85% of children develop a fall in lung function of 15% or more after a six minute ergometer cycle test. With typical EIA the fall may be totally or partially abolished by prophylactic medication 10 minutes before the start of the test. Disodium cromoglycate (Intal) and/or beta-adrenergic drugs are regularly used before all physical activity. Training programmes must be based on the interval principle. Swimming, ball games, relay races and dancing are examples of useful activities in the training and rehabilitation of children and adolescents with asthma. Through prophylactic medication and physical training, the aerobic work capacity, muscle strength and lung function in asthmatic children is improved. Training also leads to a significant mobilisation of mental resources and an increase in social integration. PMID:6958045

  4. Daily Spousal Influence on Physical Activity in Knee Osteoarthritis

    Martire, Lynn M.; Stephens, Mary Ann Parris; Mogle, Jacqueline; Schulz, Richard; Brach, Jennifer; Keefe, Francis J.

    2012-01-01

    Background Physical activity is critical for the management of knee osteoarthritis, and the spouse may play a role in encouraging or discouraging physical activity. Purpose To examine four types of spousal influence—spouses' daily activity, autonomy support, pressure, and persuasion--on the daily physical activity of adults living with knee osteoarthritis. Methods A total of 141 couples reported their daily experiences for 22 days using a handheld computer, and wore an accelerometer to measure moderate activity and steps. Results Spouses' autonomy support for patient physical activity, as well as their own level of activity, was concurrently associated with patients' greater daily moderate activity and steps. In addition, on days when male patients perceived that spouses exerted more pressure to be active, they spent less time in moderate activity. Conclusions Couple-oriented interventions for knee osteoarthritis should target physical activity in both partners and spousal strategies for helping patients stay active. PMID:23161472

  5. Physical activity - preventive medicine (image)

    Physical activity contributes to health by reducing the heart rate, decreasing the risk for cardiovascular disease, and reducing ... loss that is associated with age and osteoporosis. Physical activity also helps the body use calories more efficiently, ...

  6. Physical Activity and Psoriatic Arthritis

    ... out more! Email * Zipcode Physical Activity and Psoriatic Arthritis Physical activity plays an important role in overall well-being. If you have psoriatic arthritis, moderate exercise may offer specific benefits, including improved ...

  7. Physical Activity and Your Heart

    ... page from the NHLBI on Twitter. What Is Physical Activity? Español Physical activity is any body movement that works your muscles ... yoga, and gardening are a few examples of physical activity. According to the Department of Health and Human ...

  8. Assessing and Increasing Physical Activity

    Van Camp, Carole M.; Hayes, Lynda B.

    2012-01-01

    Increasing physical activity is a crucial component of any comprehensive approach to combat the growing obesity epidemic. This review summarizes recent behavioral research on the measurement of physical activity and interventions aimed at increasing physical activity and provides directions for future research.

  9. Physical activity: an unknown concept

    Cloes, Marc

    2016-01-01

    Physical educators do not have necesseraly good representations about physical activity and sedentariness. During the presentation, participants will be involved in an interactive process aiming to underline the main concepts that they should use in order to become effective agents of physical activity promotion.

  10. Physical activity in obesity.

    Wouters, Eveline; Geenen,

    2011-01-01

    Physical exercise education in overweight and obese patients not only requires knowledge of physical exercise programs, but also knowledge of psychological processes such as cognitions that may hamper adherence to the exercise program and knowledge of social processes, e.g., consciousness of the sti

  11. Physical activity in obesity

    Wouters, Eveline; Geenen, Rinie

    2011-01-01

    Physical exercise education in overweight and obese patients not only requires knowledge of physical exercise programs, but also knowledge of psychological processes such as cognitions that may hamper adherence to the exercise program and knowledge of social processes, e.g., consciousness of the sti

  12. Effects of mop handle height on shoulder muscle activity and perceived exertion during floor mopping using a figure eight method.

    Wallius, Mari-Anne; Rissanen, Saara M; Bragge, Timo; Vartiainen, Paavo; Karjalainen, Pasi A; Räsänen, Kimmo; Järvelin-Pasanen, Susanna

    2016-01-01

    The aim of this study was to investigate effects of mop handle height on electromyographic (EMG) activities of the shoulder muscles and perceived exertion for the shoulder area during floor mopping using a figure eight method. An experimental study with 13 cleaners was conducted using surface EMG and category ratio (CR-10) scale. EMG activity was recorded unilaterally from the upper trapezius, infraspinatus, anterior and middle deltoid muscles. Each subject performed four trials of mopping and each trial consisted of using a different mop handle height (mop adjustment at the level of shoulder, chin, nose and eye) in randomized order. EMG data were normalized to a percentage of maximal voluntary contraction (%MVC). The muscle activities were assessed by estimating the 10th, 50th and 90th percentiles of the amplitude probability distribution function (APDF) of the EMG signals and analysed by linear mixed model analysis. Results showed that shoulder muscle activity was significantly lower when the mop handle height was adjusted to shoulder level or chin level as compared to eye level. These findings were supported by subjective ratings of exertion. It seems that mop handle height adjustment between shoulder and chin level may be recommended as a basis for figure eight mopping. PMID:26423328

  13. Does an Exercise Intervention Improving Aerobic Capacity Among Construction Workers Also Improve Musculoskeletal Pain, Work Ability, Productivity, Perceived Physical Exertion, and Sick Leave?

    Gram, Bibi; Holtermann, Andreas; Bültmann, Ute;

    2012-01-01

    OBJECTIVE:: To investigate whether an exercise intervention shown to increase aerobic capacity, would also lead to less musculoskeletal pain; improved work ability, productivity, and perceived physical exertion; and less sick leave. METHODS:: Sixty-seven construction workers were randomized into ...... a more multifaceted intervention, larger sample size, or longer follow-up. Text messages may be a convenient data-collection method in future studies....

  14. Perceived physical exertion during healthcare work and prognosis for recovery from long-term pain in different body regions: Prospective cohort study

    Andersen Lars L; Clausen Thomas; Persson Roger; Holtermann Andreas

    2012-01-01

    Abstract Background The prevalence of musculoskeletal pain is high among healthcare workers. Knowledge about risk factors at work is needed to efficiently target preventive strategies. This study estimates the prognosis for recovery from long-term musculoskeletal pain in different body regions among healthcare workers with different levels of perceived physical exertion during healthcare work. Methods Prospective cohort study among 4,977 Danish female healthcare workers responding to a baseli...

  15. Effects of Combined Training with Breathing Resistance and Sustained Physical Exertion to Improve Endurance Capacity and Respiratory Muscle Function in Healthy Young Adults

    Kido, Satoshi; Nakajima, Yasuhiro; Miyasaka, Tomoya; Maeda, Yusuke; Tanaka, Toshiaki; Yu, Wenwei; Maruoka, Hiroshi; Takayanagi, Kiyomi

    2013-01-01

    [Purpose] In this study, combined training with breathing resistance and sustained physical exertion was carried out to evaluate its physiological effects and its effect on improve endurance capacity. [Subjects and Methods] The subjects were nine healthy adults (mean age 20.4, SD ± 1.7 years). The combined training group (n = 5) carried out 6 weeks of combined training using a cycle ergometer, with exercise load tests and respiratory function tests performed before and after the training. The...

  16. Physical activity and human health

    Paulina Wojciechowska

    2015-01-01

    Full Text Available Introduction: The dynamic development of the automotive industry, transport, and the media means that human life has become much easier. At the same time, the comfortable living conditions have decreased physical activity. Biologically conditioned, the need of activity has been minimised by the ever-increasing pace of life. As a result, it may lead to the loss of physical and mental health. Active recreation is not only an excellent source of activity, but also a source of satisfaction. Youths and adults should therefore spend their free time primarily on various forms of physical activity. Aim of the research : To evaluate the physical fitness of students who regularly practice physical exercise, those who occasionally practice, and those not practicing any form of physical activity. Material and methods : In the research we used a questionnaire of the Ruffier test and an orthostatic test. The study involved a group of 15 people aged 20–25 years. Participation in the study was entirely voluntary and anonymous. The study group consisted only of women. Results obtained from the questionnaire survey were fully reflected during exercise tests performed. Results and conclusions: Only regularly practiced physical activity has an effect on our body. Regular exercise increases our body’s physical capacity. Activity is the best means of prevention of lifestyle diseases. Youths and adults should spend their free time mainly doing various forms of physical activity.

  17. Grape pomace extract exerts antioxidant effects through an increase in GCS levels and GST activity in muscle and endothelial cells.

    Goutzourelas, Nikolaos; Stagos, Dimitrios; Housmekeridou, Anastasia; Karapouliou, Christina; Kerasioti, Efthalia; Aligiannis, Nektarios; Skaltsounis, Alexios L; Spandidos, Demetrios A; Tsatsakis, Aristidis M; Kouretas, Demetrios

    2015-08-01

    In a previous study, we demonstrated that a grape pomace extract (GPE) exerted antioxidant activity in endothelial (EA.hy926) and muscle (C2C12) cells through an increase in glutathione (GSH) levels. In the present study, in order to elucidate the mechanisms responsible for the antioxidant activity of GPE, its effects on the expression of critical antioxidant enzymes, such as catalase (CAT), superoxide dismutase (SOD)1, heme oxygenase 1 (HO-1) and gamma-glutamylcysteine synthetase (GCS) were assessed in EA.hy926 and C2C12 cells. Moreover, the effects of GPE on CAT, SOD and glutathione S-transferase (GST) enzymatic activity were evaluated. For this purpose, the C2C12 and EA.hy926 cells were treated with GPE at low and non-cytotoxic concentrations (2.5 and 10 µg/ml for the C2C12 cells; 0.068 and 0.250 µg/ml for the EA.hy926 cells) for 3, 6, 12, 18 and 24 h. Following incubation, enzymatic expression and activity were assessed. The results revealed that treatment with GPE significantly increased GCS levels and GST activity in both the C2C12 and EA.hy926 cells. However, GPE significantly decreased CAT levels and activity, but only in the muscle cells, while it had no effect on CAT levels and activity in the endothelial cells. Moreover, treatment with GPE had no effect on HO-1 and SOD expression and activity in both cell lines. Therefore, the present results provide further evidence of the crucial role of GSH systems in the antioxidant effects exerted by GPE. Thus, GPE may prove to be effective for use as a food supplement for the treatment of oxidative stress-induced pathological conditions of the cardiovascular and skeletal muscle systems, particularly those associated with low GSH levels. PMID:26082074

  18. Physical activity extends life expectancy

    Leisure-time physical activity is associated with longer life expectancy, even at relatively low levels of activity and regardless of body weight, according to a study by a team of researchers led by the NCI.

  19. 3,6-O-[N-(2-Aminoethyl)-acetamide-yl]-chitosan exerts antibacterial activity by a membrane damage mechanism.

    Yan, Feilong; Dang, Qifeng; Liu, Chengsheng; Yan, Jingquan; Wang, Teng; Fan, Bing; Cha, Dongsu; Li, Xiaoli; Liang, Shengnan; Zhang, Zhenzhen

    2016-09-20

    A novel chitosan derivative, 3,6-O-[N-(2-aminoethyl)-acetamide-yl]-chitosan (AACS), was successfully prepared to improve water solubility and antibacterial activity of chitosan. AACS had good antibacterial activity, with minimum inhibitory concentrations of 0.25mg/mL, against Escherichia coli and Staphylococcus aureus. Cell membrane integrity, electric conductivity and NPN uptake tests showed that AACS caused quickly increasing the release of intracellular nucleic acids, the uptake of NPN, and the electric conductivity by damaging membrane integrity. On the other hand, hydrophobicity, cell viability and SDS-PAGE experiments indicated that AACS was able to reduce the surface hydrophobicity, the cell viability and the intracellular proteins through increasing membrane permeability. SEM observation further confirmed that AACS could kill bacteria via disrupting their membranes. All results above verified that AACS mainly exerted antibacterial activity by a membrane damage mechanism, and it was expected to be a new food preservative. PMID:27261735

  20. Interdisciplinarity in Adapted Physical Activity

    Bouffard, Marcel; Spencer-Cavaliere, Nancy

    2016-01-01

    It is commonly accepted that inquiry in adapted physical activity involves the use of different disciplines to address questions. It is often advanced today that complex problems of the kind frequently encountered in adapted physical activity require a combination of disciplines for their solution. At the present time, individual research…

  1. Physical Activity and Academic Achievement

    2014-12-09

    This podcast highlights the evidence that supports the link between physical activity and improved academic achievement. It also identifies a few actions to support a comprehensive school physical activity program to improve academic achievement.  Created: 12/9/2014 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 12/9/2014.

  2. Increasing Youth Physical Activity with Activity Calendars

    Eckler, Seth

    2016-01-01

    Physical educators often struggle with ways to get their students to be active beyond the school day. One strategy to accomplish this is the use of physical activity calendars (PACs). The purpose of this article is to support the use of PACs and give practical advice for creating effective PACs.

  3. The Novel Dipeptide Translocator Protein Ligand, Referred to As GD-23, Exerts Anxiolytic and Nootropic Activities

    Povarnina, P. Yu.; Yarkov, S. A.; Gudasheva, T. A.; Yarkova, M. A.; Seredenin, S. B.

    2015-01-01

    The translocator protein (TSPO) promotes the translocation of cholesterol to the inner mitochondrial membrane and mediates steroid formation. In this study, we first report on a biological evaluation of the dipeptide GD-23 (N-carbobenzoxy-L tryptophanyl-L isoleucine amide), a structural analogue of Alpidem, the principal TSPO ligand. We show that GD-23 in a dose range of 0.05 to 0.5 mg/kg (i.p.) exhibits anxiolytic activity in the elevated plus maze test and nootropic activity in the object recognition test in scopolamine-induced amnesia in rodents. It was shown that GD-23 did not affect spontaneous locomotor activity, holding promise as a nonsedative anxiolytic agent. The anxiolytic and nootropic activities of GD-23 were abrogated by the TSPO specific ligand PK11195, which thus suggests a role for TSPO in mediating the pharmacological activity of GD-23. PMID:26483966

  4. The chalcone compound isosalipurposide (ISPP) exerts a cytoprotective effect against oxidative injury via Nrf2 activation

    The chalcone compound isosalipurposide (ISPP) has been successfully isolated from the native Korean plant species Corylopsis coreana Uyeki (Korean winter hazel). However, the therapeutic efficacy of ISPP remains poorly understood. This study investigated whether ISPP has the capacity to activate NF-E2-related factor (Nrf2)-antioxidant response element (ARE) signaling and induce its target gene expression, and to determined the protective role of ISPP against oxidative injury of hepatocytes. In HepG2 cells, nuclear translocation of Nrf2 is augmented by ISPP treatment. Consistently, ISPP increased ARE reporter gene activity and the protein levels of glutamate cysteine ligase (GCL) and hemeoxygenase (HO-1), resulting in increased intracellular glutathione levels. Cells pretreated with ISPP were rescued from tert-butylhydroperoxide-induced reactive oxygen species (ROS) production and glutathione depletion and consequently, apoptotic cell death. Moreover, ISPP ameliorated the mitochondrial dysfunction and apoptosis induced by rotenone which is an inhibitor of complex 1 of the mitochondrial respiratory chain. The specific role of Nrf2 activation by ISPP was demonstrated using an ARE-deletion mutant plasmid and Nrf2-knockout cells. Finally, we observed that extracellular signal-regulated kinase (ERK) and AMP-activated protein kinase (AMPK), but not protein kinase C (PKC)-δ or other mitogen-activated protein kinases (MAPKs), are involved in the activation of Nrf2 by ISPP. Taken together, our results demonstrate that ISPP has a cytoprotective effect against oxidative damage mediated through Nrf2 activation and induction of its target gene expression in hepatocytes. - Highlights: • We investigated the effect of ISPP on Nrf2 activation. • ISPP increased Nrf2 activity and its target gene expression. • ISPP inhibited the mitochondrial dysfunction and ROS production. • Nrf2 activation by ISPP is dependent on ERK1/2 and AMPK phosphorylation. • ISPP may be a promising

  5. The chalcone compound isosalipurposide (ISPP) exerts a cytoprotective effect against oxidative injury via Nrf2 activation

    Han, Jae Yun [College of Pharmacy, Chosun University, Gwangju 501-759 (Korea, Republic of); Cho, Seung Sik [College of Pharmacy, Mokpo National University, Muan, Jeonnam 535-729 (Korea, Republic of); Yang, Ji Hye; Kim, Kyu Min; Jang, Chang Ho [College of Pharmacy, Chosun University, Gwangju 501-759 (Korea, Republic of); Park, Da Eon [College of Pharmacy, Mokpo National University, Muan, Jeonnam 535-729 (Korea, Republic of); Bang, Joon Seok [Graduate School of Clinical Pharmacy, Sookmyung Women' s University, Seoul (Korea, Republic of); Jung, Young Suk [College of Pharmacy, Pusan National University, Busan (Korea, Republic of); Ki, Sung Hwan, E-mail: shki@chosun.ac.kr [College of Pharmacy, Chosun University, Gwangju 501-759 (Korea, Republic of)

    2015-08-15

    The chalcone compound isosalipurposide (ISPP) has been successfully isolated from the native Korean plant species Corylopsis coreana Uyeki (Korean winter hazel). However, the therapeutic efficacy of ISPP remains poorly understood. This study investigated whether ISPP has the capacity to activate NF-E2-related factor (Nrf2)-antioxidant response element (ARE) signaling and induce its target gene expression, and to determined the protective role of ISPP against oxidative injury of hepatocytes. In HepG2 cells, nuclear translocation of Nrf2 is augmented by ISPP treatment. Consistently, ISPP increased ARE reporter gene activity and the protein levels of glutamate cysteine ligase (GCL) and hemeoxygenase (HO-1), resulting in increased intracellular glutathione levels. Cells pretreated with ISPP were rescued from tert-butylhydroperoxide-induced reactive oxygen species (ROS) production and glutathione depletion and consequently, apoptotic cell death. Moreover, ISPP ameliorated the mitochondrial dysfunction and apoptosis induced by rotenone which is an inhibitor of complex 1 of the mitochondrial respiratory chain. The specific role of Nrf2 activation by ISPP was demonstrated using an ARE-deletion mutant plasmid and Nrf2-knockout cells. Finally, we observed that extracellular signal-regulated kinase (ERK) and AMP-activated protein kinase (AMPK), but not protein kinase C (PKC)-δ or other mitogen-activated protein kinases (MAPKs), are involved in the activation of Nrf2 by ISPP. Taken together, our results demonstrate that ISPP has a cytoprotective effect against oxidative damage mediated through Nrf2 activation and induction of its target gene expression in hepatocytes. - Highlights: • We investigated the effect of ISPP on Nrf2 activation. • ISPP increased Nrf2 activity and its target gene expression. • ISPP inhibited the mitochondrial dysfunction and ROS production. • Nrf2 activation by ISPP is dependent on ERK1/2 and AMPK phosphorylation. • ISPP may be a promising

  6. Barriers for recess physical activity

    Pawlowski, Charlotte Skau; Tjørnhøj-Thomsen, Tine; Schipperijn, Jasper;

    2014-01-01

    ) with in total 111 children (53 boys) from fourth grade, with a mean age of 10.4 years. The focus groups included an open group discussion, go-along group interviews, and a gender segregated post-it note activity. A content analysis of the post-it notes was used to rank the children's perceived barriers......BACKGROUND: Many children, in particular girls, do not reach the recommended amount of daily physical activity. School recess provides an opportunity for both boys and girls to be physically active, but barriers to recess physical activity are not well understood. This study explores gender...... differences in children's perceptions of barriers to recess physical activity. Based on the socio-ecological model four types of environmental barriers were distinguished: natural, social, physical and organizational environment. METHODS: Data were collected through 17 focus groups (at 17 different schools...

  7. Does expiratory muscle activity influence dynamic hyperinflation and exertional dyspnea in COPD?

    Laveneziana, Pierantonio; Webb, Katherine A; Wadell, Karin; Neder, J Alberto; O'Donnell, Denis E

    2014-08-01

    Increased expiratory muscle activity is common during exercise in patients with COPD but its role in modulating operating lung volumes and dyspnea during incremental cycle ergometry is currently unknown. We compared gastric (Pga) and esophageal (Pes) pressures, operating lung volumes and qualitative descriptors of dyspnea during exercise in 12 COPD patients and 12 age- and sex-matched healthy controls. Pes- and Pga-derived measures of expiratory muscle activity were significantly (ptolerance. In conclusion, increased expiratory muscle activity did not mitigate the rise in EELV, the relatively early respiratory mechanical constraints or the attendant perceived inspiratory difficulty during exercise in COPD. PMID:24793133

  8. Energy Balance and Physical Activity

    2001-01-01

    The prevalence of obesity is increasing in most parts of theworld and becoming one of the major global public health problems. Although the components of energy balance have not been adequately estimated over time, available evidence suggests that the increase in obesity is the result of reduced physical activity. Increases in physical activity have been shown to be strongly associated with improving physical fitness and body composition, with probably a positive effect on resting metabolic rate. The Surgeon General's Report on Physical Activity and Health advocates that 30 min of regular, moderate-intensity physical activity is associated with decreases in the risk of chronic diseases and may contribute to quality of life. However, the small changes that contribute 10 min for 3 times a day for aerobic training, or one set instead of three sets of repetitions on resistance training will provide individuals with health benefits. Indeed, nutrition and physical activity should be considered an integral part of fitness and good health, and should be encouraged in all age groups, particularly early in life. The question is no longer centered around the health benefit of increasing physical activity, but rather creating self awareness and behavior changes in individuals. Hence, effective intervention programs are needed that foster long term changes in physical activity. Among various interventions, the Nutrifit program was recently conducted in Thailand and found to improve health related fitness in children. The development of more effective interventions and approaches is a major challenge in this field today.

  9. Essential Oil of Pinus koraiensis Exerts Antiobesic and Hypolipidemic Activity via Inhibition of Peroxisome Proliferator-Activated Receptors Gamma Signaling

    Hyun-Suk Ko; Hyo-Jeong Lee; Hyo-Jung Lee; Eun Jung Sohn; Miyong Yun; Min-Ho Lee; Sung-Hoon Kim

    2013-01-01

    Our group previously reported that essential oil of Pinus koraiensis (EOPK) exerts antihyperlipidemic effects via upregulation of low-density lipoprotein receptor and inhibition of acyl-coenzyme A. In the present study, we investigated the antiobesity and hypolipidemic mechanism of EOPK using in vitro 3T3-L1 cells and in vivo HFD-fed rats. EOPK markedly suppressed fat accumulation and intracellular triglyceride associated with downregulation of adipogenic transcription factor expression, incl...

  10. Physics of solar activity

    Sturrock, Peter A.

    1993-01-01

    The aim of the research activity was to increase our understanding of solar activity through data analysis, theoretical analysis, and computer modeling. Because the research subjects were diverse and many researchers were supported by this grant, a select few key areas of research are described in detail. Areas of research include: (1) energy storage and force-free magnetic field; (2) energy release and particle acceleration; (3) radiation by nonthermal electrons; (4) coronal loops; (5) flare classification; (6) longitude distributions of flares; (7) periodicities detected in the solar activity; (8) coronal heating and related problems; and (9) plasma processes.

  11. THE NOVEL DIPEPTIDE TRANSLOCATOR PROTEIN LIGAND, REFERRED TO AS GD-23, EXERTS ANXIOLYTIC AND NOOTROPIC ACTIVITIES

    POVARNINA P. YU.; YARKOV S.A.; Gudasheva, T.A.; Yarkova, M. A.; Seredenin, S.B.

    2015-01-01

    The translocator protein (TSPO) promotes the translocation of cholesterol to the inner mitochondrial membrane and mediates steroid formation. In this study, we first report on a biological evaluation of the dipeptide GD-23 (N-carbobenzoxy-L tryptophanyl-L isoleucine amide), a structural analogue of Alpidem, the principal TSPO ligand. We show that GD-23 in a dose range of 0.05 to 0.5 mg/kg (i.p.) exhibits anxiolytic activity in the elevated plus maze test and nootropic activity in the object r...

  12. Labdanolic acid methyl ester (LAME) exerts anti-inflammatory effects through inhibition of TAK-1 activation

    Cuadrado, Irene [Departamento de Farmacología, Facultad de Farmacia, Universidad Complutense, Plaza Ramón y Cajal s/n, 28040 Madrid (Spain); Cidre, Florencia; Herranz, Sandra [Unidad de Inflamación y Cáncer. Área de Biología Celular y Desarrollo. Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid (Spain); Estevez-Braun, Ana [Instituto Universitario de Bio-Orgánica “Antonio González”. Universidad de La Laguna. Avda. Astrofísico Fco. Sánchez 2. 38206. La Laguna, Tenerife (Spain); Instituto Canario de Investigaciones del Cáncer (ICIC) (Spain); Heras, Beatriz de las, E-mail: lasheras@farm.ucm.es [Departamento de Farmacología, Facultad de Farmacia, Universidad Complutense, Plaza Ramón y Cajal s/n, 28040 Madrid (Spain); Hortelano, Sonsoles, E-mail: shortelano@isciii.es [Unidad de Inflamación y Cáncer. Área de Biología Celular y Desarrollo. Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid (Spain)

    2012-01-01

    Labdane derivatives obtained from the diterpenoid labdanediol suppressed NO and PGE{sub 2} production in LPS-stimulated RAW 264.7 macrophages. However, mechanisms involved in these inhibitory effects are not elucidated. In this study, we investigated the signaling pathways involved in the anti-inflammatory effects of labdanolic acid methyl ester (LAME) in peritoneal macrophages and examined its therapeutic effect in a mouse endotoxic shock model. LAME reduced the production of NO and PGE{sub 2} in LPS-activated macrophages. This effect involved the inhibition of NOS-2 and COX-2 gene expression, acting at the transcription level. Examination of the effects of the diterpene on NF-κB signaling showed that LAME inhibits the phosphorylation of IκBα and IκBβ, preventing their degradation and the nuclear translocation of the NF-κB p65 subunit. Moreover, inhibition of MAPK signaling was also observed. A further experiment revealed that LAME inhibited the phosphorylation of transforming growth factor-β (TGF-β)-activated kinase 1 (TAK1), an upstream signaling molecule required for IKK and mitogen-activated protein kinases (MAPKs) activation. Inflammatory cytokines such as IL-6, TNF-α and IP-10 were downregulated in the presence of this compound after stimulation with LPS. Additionally, LAME also improved survival in a mouse model of endotoxemia and reduced the circulatory levels of cytokines (IL-6, TNF-α). In conclusion, these results indicate that labdane diterpene LAME significantly attenuates the pro-inflammatory response induced by LPS both in vivo and in vitro. Highlights: ► LAME reduced the production of NO and PGE{sub 2} in LPS-activated macrophages. ► IL-6, TNF-α and IP-10 were also inhibited by LAME. ► Inhibition of TAK-1 activation is the mechanism involved in this process. ► LAME improved survival in a mouse model of endotoxemia. ► LAME reduced the circulatory levels of cytokines (IL-6, TNF-α).

  13. Labdanolic acid methyl ester (LAME) exerts anti-inflammatory effects through inhibition of TAK-1 activation

    Labdane derivatives obtained from the diterpenoid labdanediol suppressed NO and PGE2 production in LPS-stimulated RAW 264.7 macrophages. However, mechanisms involved in these inhibitory effects are not elucidated. In this study, we investigated the signaling pathways involved in the anti-inflammatory effects of labdanolic acid methyl ester (LAME) in peritoneal macrophages and examined its therapeutic effect in a mouse endotoxic shock model. LAME reduced the production of NO and PGE2 in LPS-activated macrophages. This effect involved the inhibition of NOS-2 and COX-2 gene expression, acting at the transcription level. Examination of the effects of the diterpene on NF-κB signaling showed that LAME inhibits the phosphorylation of IκBα and IκBβ, preventing their degradation and the nuclear translocation of the NF-κB p65 subunit. Moreover, inhibition of MAPK signaling was also observed. A further experiment revealed that LAME inhibited the phosphorylation of transforming growth factor-β (TGF-β)-activated kinase 1 (TAK1), an upstream signaling molecule required for IKK and mitogen-activated protein kinases (MAPKs) activation. Inflammatory cytokines such as IL-6, TNF-α and IP-10 were downregulated in the presence of this compound after stimulation with LPS. Additionally, LAME also improved survival in a mouse model of endotoxemia and reduced the circulatory levels of cytokines (IL-6, TNF-α). In conclusion, these results indicate that labdane diterpene LAME significantly attenuates the pro-inflammatory response induced by LPS both in vivo and in vitro. Highlights: ► LAME reduced the production of NO and PGE2 in LPS-activated macrophages. ► IL-6, TNF-α and IP-10 were also inhibited by LAME. ► Inhibition of TAK-1 activation is the mechanism involved in this process. ► LAME improved survival in a mouse model of endotoxemia. ► LAME reduced the circulatory levels of cytokines (IL-6, TNF-α).

  14. Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma

    Yongxia Zhu; Tinghong Ye; Xi Yu; Qian Lei; Fangfang Yang; Yong Xia; Xuejiao Song; Li Liu; Hongxia Deng; Tiantao Gao; Cuiting Peng; Weiqiong Zuo; Ying Xiong; Lidan Zhang; Ningyu Wang

    2016-01-01

    Melanoma is a highly malignant neoplasm of melanocytes with considerable metastatic potential and drug resistance, explaining the need for new candidates that inhibit tumor growth and metastasis. The signal transducer and activator of the transcription 3 (Stat3) signaling pathway plays an important role in melanoma and has been validated as promising anticancer target for melanoma therapy. In this study, nifuroxazide, an antidiarrheal agent identified as an inhibitor of Stat3, was evaluated f...

  15. Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma.

    Zhu, Yongxia; Ye, Tinghong; Yu, Xi; Lei, Qian; Yang, Fangfang; Xia, Yong; Song, Xuejiao; Liu, Li; Deng, Hongxia; Gao, Tiantao; Peng, Cuiting; Zuo, Weiqiong; Xiong, Ying; Zhang, Lidan; Wang, Ningyu; Zhao, Lifeng; Xie, Yongmei; Yu, Luoting; Wei, Yuquan

    2016-01-01

    Melanoma is a highly malignant neoplasm of melanocytes with considerable metastatic potential and drug resistance, explaining the need for new candidates that inhibit tumor growth and metastasis. The signal transducer and activator of the transcription 3 (Stat3) signaling pathway plays an important role in melanoma and has been validated as promising anticancer target for melanoma therapy. In this study, nifuroxazide, an antidiarrheal agent identified as an inhibitor of Stat3, was evaluated for its anti-melanoma activity in vitro and in vivo. It had potent anti-proliferative activity against various melanoma cell lines and could induce G2/M phase arrest and cell apoptosis. Moreover, nifuroxazide markedly impaired melanoma cell migration and invasion by down-regulating phosphorylated-Src, phosphorylated-FAK, and expression of matrix metalloproteinase (MMP) -2, MMP-9 and vimentin. It also significantly inhibited tumor growth without obvious side effects in the A375-bearing mice model by inducing apoptosis and reducing cell proliferation and metastasis. Notably, nifuroxazide significantly inhibited pulmonary metastases, which might be associated with the decrease of myeloid-derived suppressor cells (MDSCs). These findings suggested that nifuroxazide might be a potential agent for inhibiting the growth and metastasis of melanoma. PMID:26830149

  16. Highly homologous proteins exert opposite biological activities by using different interaction interfaces.

    Amir, Anat Iosub; van Rosmalen, Martijn; Mayer, Guy; Lebendiker, Mario; Danieli, Tsafi; Friedler, Assaf

    2015-01-01

    We present a possible molecular basis for the opposite activity of two homologues proteins that bind similar ligands and show that this is achieved by fine-tuning of the interaction interface. The highly homologous ASPP proteins have opposite roles in regulating apoptosis: ASPP2 induces apoptosis while iASPP inhibits it. The ASPP proteins are regulated by an autoinhibitory interaction between their Ank-SH3 and Pro domains. We performed a detailed biophysical and molecular study of the Pro - Ank-SH3 interaction in iASPP and compared it to the interaction in ASPP2. We found that iASPP Pro is disordered and that the interaction sites are entirely different: iASPP Ank-SH3 binds iASPP Pro via its fourth Ank repeat and RT loop while ASPP2 Ank-SH3 binds ASPP2 Pro via its first Ank repeat and the n-src loop. It is possible that by using different moieties in the same interface, the proteins can have distinct and specific interactions resulting in differential regulation and ultimately different biological activities. PMID:26130271

  17. Nitric Oxide Synthase Type III Overexpression By Gene Therapy Exerts Antitumoral Activity In Mouse Hepatocellular Carcinoma

    Raúl González

    2015-08-01

    Full Text Available Hepatocellular carcinoma develops in cirrhotic liver. The nitric oxide (NO synthase type III (NOS-3 overexpression induces cell death in hepatoma cells. The study developed gene therapy designed to specifically overexpress NOS-3 in cultured hepatoma cells, and in tumors derived from orthotopically implanted tumor cells in fibrotic livers. Liver fibrosis was induced by CCl4 administration in mice. Hepa 1-6 cells were used for in vitro and in vivo experiments. The first generation adenovirus was designed to overexpress NOS-3 (or GFP and luciferase cDNA under the regulation of murine alpha-fetoprotein (AFP and Rous Sarcoma Virus (RSV promoters, respectively. Both adenoviruses were administered through the tail vein two weeks after orthotopic tumor cell implantation. AFP-NOS-3/RSV-Luciferase increased oxidative-related DNA damage, p53, CD95/CD95L expression and caspase-8 activity in cultured Hepa 1-6 cells. The increased expression of CD95/CD95L and caspase-8 activity was abolished by l-NAME or p53 siRNA. The tail vein infusion of AFP-NOS- 3/RSV-Luciferase adenovirus increased cell death markers, and reduced cell proliferation of established tumors in fibrotic livers. The increase of oxidative/nitrosative stress induced by NOS-3 overexpression induced DNA damage, p53, CD95/CD95L expression and cell death in hepatocellular carcinoma cells. The effectiveness of the gene therapy has been demonstrated in vitro and in vivo.

  18. (+)-Cannabidiol analogues which bind cannabinoid receptors but exert peripheral activity only.

    Fride, Ester; Feigin, Cfir; Ponde, Datta E; Breuer, Aviva; Hanus, Lumír; Arshavsky, Nina; Mechoulam, Raphael

    2004-12-15

    Delta9-Tetrahydrocannabinol (Delta9-THC) and (-)-cannabidiol are major constituents of the Cannabis sativa plant with different pharmacological profiles: (-)-Delta9-tetrahydrocannabinol, but not (-)-cannabidiol, activates cannabinoid CB1 and CB2 receptors and induces psychoactive and peripheral effects. We have tested a series of (+)-cannabidiol derivatives, namely, (+)-cannabidiol-DMH (DMH-1,1-dimethylheptyl-), (+)-7-OH-cannabidiol-DMH, (+)-7-OH- cannabidiol, (+)-7-COOH- cannabidiol and (+)-7-COOH-cannabidiol-DMH, for central and peripheral (intestinal, antiinflammatory and peripheral pain) effects in mice. Although all (+)-cannabidiols bind to cannabinoid CB1 and CB2 receptors, only (+)-7-OH-cannabidiol-DMH was centrally active, while all (+)-cannabidiol analogues completely arrested defecation. The effects of (+)-cannabidiol-DMH and (+)-7-OH-cannabidiol-DMH were partially antagonized by the cannabinoid CB1 receptor antagonist N-(piperidiny-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716), but not by the cannabinoid CB2 receptor antagonist N-[-(1S)-endo-1,3,3-trimethil bicyclo [2.2.1] heptan-2-yl-5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)-pyrazole-3-carboxamide (SR144528), and had no effect on CB1(-/-) receptor knockout mice. (+)-Cannabidiol-DMH inhibited the peripheral pain response and arachidonic-acid-induced inflammation of the ear. We conclude that centrally inactive (+)-cannabidiol analogues should be further developed as antidiarrheal, antiinflammatory and analgesic drugs for gastrointestinal and other peripheral conditions. PMID:15588739

  19. Various Acylglycerols from Common Oils Exert Different Antitumor Activities on Colorectal Cancer Cells.

    Ramos-Bueno, Rebeca P; González-Fernández, María J; Guil-Guerrero, José L

    2016-04-01

    Colorectal cancer is one of the leading causes of death in Western countries; therefore, the implementation of healthy dietary habits in order to prevent its occurrence is a desirable action. We show here that both free fatty acids (FFAs) and some acylglycerols induce antitumoral actions in the colorectal cancer cell line HT-29. We tested several C18 polyunsaturated fatty acid-enriched oils (e.g., sunflower and Echium) as well as other oils, such as arachidonic acid-enriched (Arasco®) and docosahexaenoic acid-enriched (Marinol® and cod liver oil), in addition to coconut and olive oils. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test indicated inhibitory effects on HT-29 cells viability for FFAs, and monoacylglycerol and diacylglycerol (DAG) species, while the lactate dehydrogenase test proved that FFAs were the more effective species to induce membrane injury. Conversely, all species did not exhibit actions on CCD-18 normal human colon cells viability. Furthermore, transmission electron microscopy showed the presence of necrosis and apoptosis, while the monoacylglycerol lipase (MAGL) inhibition test demonstrated high activity for 2-monoacylglycerols derived from Arasco and sunflower oils. However, different monoacylglycerols and DAGs have also the potential for MAGL inhibition. Therefore, checking for activity on colon cancer cells of specifically designed acylglycerol-derivative species would be a suitable way to design functional foods destined to avoid colorectal cancer initiation. PMID:27007804

  20. Highly homologous proteins exert opposite biological activities by using different interaction interfaces

    Iosub Amir, Anat; van Rosmalen, Martijn; Mayer, Guy; Lebendiker, Mario; Danieli, Tsafi; Friedler, Assaf

    2015-07-01

    We present a possible molecular basis for the opposite activity of two homologues proteins that bind similar ligands and show that this is achieved by fine-tuning of the interaction interface. The highly homologous ASPP proteins have opposite roles in regulating apoptosis: ASPP2 induces apoptosis while iASPP inhibits it. The ASPP proteins are regulated by an autoinhibitory interaction between their Ank-SH3 and Pro domains. We performed a detailed biophysical and molecular study of the Pro - Ank-SH3 interaction in iASPP and compared it to the interaction in ASPP2. We found that iASPP Pro is disordered and that the interaction sites are entirely different: iASPP Ank-SH3 binds iASPP Pro via its fourth Ank repeat and RT loop while ASPP2 Ank-SH3 binds ASPP2 Pro via its first Ank repeat and the n-src loop. It is possible that by using different moieties in the same interface, the proteins can have distinct and specific interactions resulting in differential regulation and ultimately different biological activities.

  1. Resveratrol inhibits Trypanosoma cruzi arginine kinase and exerts a trypanocidal activity.

    Valera Vera, Edward A; Sayé, Melisa; Reigada, Chantal; Damasceno, Flávia S; Silber, Ariel M; Miranda, Mariana R; Pereira, Claudio A

    2016-06-01

    Arginine kinase catalyzes the reversible transphosphorylation between ADP and phosphoarginine which plays a critical role in the maintenance of cellular energy homeostasis. Arginine kinase from the protozoan parasite Trypanosoma cruzi, the etiologic agent of Chagas disease, meets the requirements to be considered as a potential therapeutic target for rational drug design including being absent in its mammalian hosts. In this study a group of polyphenolic compounds was evaluated as potential inhibitors of arginine kinase using molecular docking techniques. Among the analyzed compounds with the lowest free binding energy to the arginine kinase active site (market price; and (3) has as a well-defined target enzyme which is absent in the mammalian host, it is a promising compound as a trypanocidal drug for Chagas disease. PMID:26976067

  2. Salvicine, a novel topoisomerase II inhibitor, exerts its potent anticancer activity by ROS generation.

    Meng, Ling-hua; Ding, Jian

    2007-09-01

    Salvicine is a novel diterpenoid quinone compound obtained by structural modification of a natural product lead isolated from a Chinese herb with potent growth inhibitory activity against a wide spectrum of human tumor cells in vitro and in mice bearing human tumor xenografts. Salvicine has also been found to have a profound cytotoxic effect on multidrug-resisitant (MDR) cells. Moreover, Salvicine significantly reduced the lung metastatic foci of MDA-MB-435 orthotopic xenograft. Recent studies demonstrated that salvicine is a novel non-intercalative topoisomerase II (Topo II) poison by binding to the ATPase domain, promoting DNA-Topo II binding and inhibiting Topo II-mediated DNA relegation and ATP hydrolysis. Further studies have indicated that salcivine-elicited ROS plays a central role in salvicine-induced cellular response including Topo II inhibition, DNA damage, circumventing MDR and tumor cell adhesion inhibition. PMID:17723179

  3. Salvicine,a novel topoisomerase Ⅱ inhibitor, exerts its potent anticancer activity by ROS generation

    Ling-hua MENG; Jian DING

    2007-01-01

    Salvicine is a novel diterpenoid quinone compound obtained by structural modi-fication of a natural product lead isolated from a Chinese herb with potent growth inhibitory activity against a wide spectrum of human tumor cells in vitro and in mice bearing human tumor xenografts. Salvicine has also been found to have a profound cytotoxic effect on multidrug-resisitant (MDR) cells. Moreover, Salvicine significantly reduced the lung metastatic foci of MDA-MB-435 orthotopic xenograft. Recent studies demonstrated that salvicine is a novel non-intercalativetopoisomerase Ⅱ (Topo Ⅱ) poison by binding to the ATPase domain, promoting DNA-Topo Ⅱ binding and inhibiting Topo Ⅱ-mediated DNA relegation and ATP hydrolysis. Further studies have indicated that salcivine-elicited ROS plays a central role in salvicine-induced cellular response including Topo II inhibition,DNA damage, circumventing MDR and tumor cell adhesion inhibition.

  4. OXIDATIVE STRESS AND PHYSICAL ACTIVITY

    Dragan Radovanović

    2012-06-01

    Full Text Available The cells continuously produce free radicals and reactive oxygen species as a part of metabolic processes. Increased aerobic metabolism during exercise is a potential source of oxidative stress. Also, anaerobic physical activity and oxidative stress are interrelated because the intense anaerobic activity leads to damage proteins, lipids and nucleic acids in muscle cells and blood. Complex system of antioxidant defense, which has the enzymatic and non-enzymatic part, has a role in protecting tissues from excessive oxidative damage. Most of the research conducted so far about the impact of various forms of physical activity on levels of oxidative stress is confirmed by changes in biomarkers that indicate lipid peroxidation and proteins modification. Untrained persons, as opposed to trained, are more susceptible to major changes in the body caused by oxidative stress during physical activity. The results of researches have shown that there are no significant differences between the genders in the level of oxidative stress during physical activity and response to antioxidant supplementation possibly applied. It is interesting that, despite of numerous studies, the exact location of oxidative stress origin during physical activity has not been reliably established. In addition, research results provide insufficient evidence on the effectiveness of using antioxidant supplementation to increase the defense against oxidative stress. It is necessary further investigation about the redox status and oxidative stress during physical activity in adolescent athletes.

  5. Surface active stabilizer Tyloxapol in colloidal dispersions exerts cytostatic effects and apoptotic dismissal of cells

    Solid lipid nanoparticles (SLN) have been praised for their advantageous drug delivery properties such as biocompatibility, controlled release and passive drug targeting. However, the cytotoxicity of SLN and their ingredients, especially over a longer time period, has not been investigated in detail. We examined the critical issues regarding the use of a surface active stabilizer Tyloxapol (Tyl) for the preparation of solid lipid particles (SLP) and their effects on cellular functions and viability. SLP composed of behenate, phospholipids and a stabilizer, Tyloxapol or Lutrol (Lut), were prepared by the lipid melt method, labeled with a fluorescent dye and tested on Jurkat or HEK293 cells. The nano-sized particles were rapidly internalized and exhibited cytoplasmic localization. Incubation of cells with SLP-Tyl resulted in a dose- and time-dependent cytostatic effect, and also caused moderate and delayed cytotoxicity. Tyloxapol solution or SLP-Tyl dispersion caused the detachment of HEK293 cells, a decrease in cell proliferation and alterations in cellular morphology. Cell cycle analysis revealed that, while the unfavourable effects of SLP-Tyl and Tyloxapol solution are similar initially, longer incubation results in partial recovery of cells incubated with the dispersion of SLP-Tyl, whereas the presence of Tyloxapol solution induces apoptotic cell death. These findings indicate that Tyloxapol is an unfavourable stabilizer of SLP used for intracellular delivery and reinforce the role of stabilizers in a design of SLP with minimal cytotoxic properties

  6. Flavonoid derivative exerts an antidiabetic effect via AMPK activation in diet-induced obesity mice.

    Chen, Ying; Zhang, Chang; Jin, Mei-Na; Qin, Nan; Qiao, Wei; Yue, Xiao-Long; Duan, Hong-Quan; Niu, Wen-Yan

    2016-09-01

    In our previous study, a derivative of tiliroside, 3-O-[(E)-4-(4-ethoxyphenyl)-2-oxobut-3-en-1-yl]kaempferol (Fla-OEt) significantly enhanced glucose consumption in insulin resistant HepG2 cells. This article deals with the antihyperglycemic and antihyperlipidemic effects of Fla-OEt in diet-induced obesity (DIO) mice. Daily administration of Fla-OEt significantly decreased oral glucose tolerance test, intraperitoneal insulin tolerance test and serum lipids. Hyperinsulinemic-euglycemic clamp and the ratio of high-density-lipoprotein/low-density-lipoprotein with Fla-OEt treatment were increased comparing with high-fat diet (HFD) group, so lipid metabolism was improved. Histopathology examination showed that the Fla-OEt restored the damage of adipose tissues and liver in DIO mice. Moreover, compared with HFD group, Fla-OEt treatment significantly increased the phosphorylation of AMPK and ACC in adiposity tissues, liver, and muscles. The mechanism of its action might be the activation of AMPK pathway. It appears that Fla-OEt is worth further study for development as a lead compound for a potential antidiabetic agent. PMID:26511291

  7. Self-Related Health, Physical Activity and Complaints in Swedish High School Students

    Marie Alricsson; Bodil J. Landstad; Ulla Romild; Suzanne Werner

    2006-01-01

    The aim of this investigation was to study self-related health, physical activity and level of exertion, as well as body complaints in Swedish high school students. A total of 993 high school students aged 16–19 years participated in the study. A questionnaire was completed at school and included questions about self-related health, physical activity behavior, type of physical activity/sport, intensity, duration, possible injuries or complaints, and absence from physical training at school, d...

  8. Physical activity: practice this idea

    Guimarães, Guilherme Veiga; Ciolac, Emmanuel Gomes

    2014-01-01

    Sedentary habits or insufficient activities to promote health benefits can influence the occurrence of chronic diseases. The cardiovascular risk factors arise, at least partially, from the individual-environment interaction during life, and worsen with aging and lack of physical exercise. Health promotion and prevention are among the greatest challenges of public health policies. However, physical activity turns out to be rarely recommended and, thus have a very poor adhesion. In spite of con...

  9. Psychosocial factors underlying physical activity

    Ji Cheng-Ye; Middlestadt Susan E; Zhang Juan

    2007-01-01

    Abstract Background Given the increasing importance of obesity in China, prevention interventions encouraging physical activity by middle school students are needed. The purpose of this study is to illustrate how a rapid elicitation method can be used to identify salient consequences, referents, and circumstances about physical activity as perceived by middle school students and to provide suggestions for interventions and quantitative research. Method A theory-based qualitative study using a...

  10. Teriflunomide, an immunomodulatory drug, exerts anticancer activity in triple negative breast cancer cells.

    Huang, Ou; Zhang, Weili; Zhi, Qiaoming; Xue, Xiaofeng; Liu, Hongchun; Shen, Daoming; Geng, Meiyu; Xie, Zuoquan; Jiang, Min

    2015-04-01

    Triple-negative breast cancer (TNBC) is defined as a group of primary breast cancers lacking expression of estrogen, progesterone, and human epidermal growth factor receptor-2 (HER-2) receptors, characterized by higher relapse rate and lower survival compared with other subtypes. Due to lack of identified targets and molecular heterogeneity, conventional chemotherapy is the only available option for treatment of TNBC, but non-discordant positive therapeutic efficacy could not be achieved. Here, we demonstrated that these TNBC cells were sensitive to teriflunomide, which was a well-known immunomodulatory drug for treatment of relapsing multiple sclerosis (MS). Potent anti-cancer effects in TNBC in vitro, including proliferation inhibition, cell cycle delay, cell apoptosis, and suppression of cell motility and invasiveness, could be achieved with this agent. Of note, we showed that multiple signals involved in TNBC proliferation, survival, migratory, and invasive potential were under regulation by teriflunomide. Among them, we identified down-regulation of growth factor receptors to abolish growth maintenance, suppression of c-Myc, and cyclin D1 to contribute to its anti-proliferative effect, modulation of components of cell cycle to induce S-phase arrest, degradation of Bcl-xL, and up-regulation of BAX via activation of MAPK pathway to induce apoptosis, and inhibition of epithelial-mesenchymal transition (EMT) process, matrix metalloproteinase-9 (MMP9) expression, and inactivation of Src/FAK to reduce TNBC migration and invasion. The results identified teriflunomide may be of therapeutic benefit for the more aggressive and difficult-to-treat breast cancer subtype, indicating the use of teriflunomide for clinical trials for treatment of TNBC patients. PMID:25304315

  11. Reactor physics activities in Japan

    This report reviews the research activity in reactor physics field in Japan during July, 1992 - July, 1993. The review was performed in the following fields : nuclear data evaluation, calculational method development, fast reactor physics, thermal reactor physics, advanced core design, fusion reactor neutronics, nuclear criticality safety, shielding, incineration of radioactive nuclear wastes, noise analysis and control and national programs. The main references were taken from journals and reports published during this period. The research committee of reactor physics is responsible for the review work. (author)

  12. ω3-PUFAs exert anti-inflammatory activity in visceral adipocytes from colorectal cancer patients.

    Massimo D'Archivio

    Full Text Available OBJECTIVE: The aim of this study was to correlate specific fatty acid profiles of visceral white adipose tissue (WAT with inflammatory signatures potentially associated with colorectal cancer (CRC. METHODS: Human adipocytes were isolated from biopsies of visceral WAT from 24 subjects subdivided in four groups: normal-weight (BMI 22.0-24.9 Kg/m2 and over-weight/obese (BMI 26.0-40.0 Kg/m2, affected or not by CRC. To define whether obesity and/or CRC affect the inflammatory status of WAT, the activation of the pro-inflammatory STAT3 and the anti-inflammatory PPARγ transcription factors as well as the expression of adiponectin were analyzed by immunoblotting in adipocytes isolated from each group of subjects. Furthermore, to evaluate whether differences in inflammatory WAT environment correlate with specific fatty acid profiles, gas-chromatographic analysis was carried out on WAT collected from all subject categories. Finally, the effect of the ω3 docosahexaenoic acid treatment on the balance between pro- and anti-inflammatory factors in adipocytes was also evaluated. RESULTS: We provide the first evidence for the existence of a pro-inflammatory environment in WAT of CRC patients, as assessed by the up-regulation of STAT3, and the concomitant decrease of PPARγ and adiponectin with respect to healthy subjects. WAT inflammatory status was independent of obesity degree but correlated with a decreased ω3-/ω6-polyunsaturated fatty acid ratio. These observations suggested that qualitative changes, other than quantitative ones, in WAT fatty acid may influence tissue dysfunctions potentially linked to inflammatory conditions. This hypothesis was further supported by the finding that adipocyte treatment with docosahexaenoic acid restored the equilibrium between STAT3 and PPARγ. CONCLUSION: Our results suggest that adipocyte dysfunctions occur in CRC patients creating a pro-inflammatory environment that might influence cancer development. Furthermore

  13. Solar Activity and Classical Physics

    2001-01-01

    This review of solar physics emphasizes several of the more conspicuous scientific puzzles posed by contemporary observational knowledge of the magnetic activity of the Sun. The puzzles emphasize how much classical physics we have yet to learn from the Sun. The physics of solar activity is based on the principles of Newton, Maxwell, Lorentz, Boltzmann, et. al., along with the principles of radiative transfer. In the large, these principles are expressed by magnetohydrodynamics. A brief derivation of the magnetohydrodynamic induction and momentum equations is provided, with a discussion of popular misconceptions.

  14. Strategies for Physical Activity Promotion beyond the Physical Education Classroom

    Faber, Larry; Kulinna, Pamela Hodges; Darst, Paul

    2007-01-01

    The current need for physical activity has extended beyond the limited time given to students in physical education classes. In order for students to receive appropriate levels of physical activity (i.e., at least 60 minutes per day), it is necessary for physical educators to incorporate physical activity opportunities outside the traditional…

  15. Energy Balance and Physical Activity

    KALLAYAKIJBOONCHOO

    2001-01-01

    The prevalence of obesity is increasing in most parts of the world and becoming one of the major global public health problems.Although the components of energy balance have not been adequately estimated over time,available evidence suggests that the increase in obesity is the result of reduced physical activity.Increases in physical activity have been showen to be strongly associated with improving physical fitness and body composition,with probably a positive effect on resting metabolic rate.The Surgeon General's Report on physical Activity and Health advocates that 30 min of regular,moderate-intensity physical activity is associated with decreases in the risk of chronic diseases and may contribute to quality of life.However,the small changes that contribute 10 min for 3 times a day for 3 times a day for aerobic training,or one set instead of three sets of repetitions on resistance training will provide individuals training,or one set instead of three sets of repetitions on resistance training will provide individuals with health benefits.Indeed,nutrition and physical activity should be considered an integral part of fitness and good health,and should be encouraged in all age groups,particularly early in life,The question is no longer centerd around the health benefit of increasing physical activity,but rather creating self awareness and behavior changes in individuals,Hence,effective intervention programs are needed that foster long term changes in physical activity.Among various interventions,the Nutrifit program was recently conducted in Thailand and found to improve health related fitness in children,The development of more effective interventions and approaches is a major challege in this field today.

  16. Psychosocial factors underlying physical activity

    Ji Cheng-Ye

    2007-09-01

    Full Text Available Abstract Background Given the increasing importance of obesity in China, prevention interventions encouraging physical activity by middle school students are needed. The purpose of this study is to illustrate how a rapid elicitation method can be used to identify salient consequences, referents, and circumstances about physical activity as perceived by middle school students and to provide suggestions for interventions and quantitative research. Method A theory-based qualitative study using a self-completion elicitation was conducted with 155 students from two middle schools in Beijing, China. Following the Theory of Planned Behavior, six open-ended questions asked students for their perceptions about performing physical activity at least 60 minutes each day: advantages of participating in physical activity; disadvantages of doing so; people who approve of participation; people who disapprove; things that make it easy; and things that make it hard. Content analysis revealed categories of salient consequences, reference groups, and circumstances. Results While the three most frequently mentioned advantages elicited from the students were physical health consequences (e.g., will strengthen my body (58.7%, four of the salient advantages were not (e.g., will improve my grades (12.2%. Parents were the most frequently mentioned social referent (42.6% as approving; 27.7% as disapproving when students were asked who might approve or disapprove of their participation. Circumstances perceived to hinder daily physical activity included having too many assignments and not having enough time. Conclusion While many of the beliefs about physical activity elicited from this study were similar to those found with students from England and the US, several were unique to these students from Beijing. The results of this qualitative research suggest that interventions to encourage physical activity among middle school students should address: perceived consequences

  17. Effects of muscle activity and number of resistance exercise repetitions on perceived exertion in tonic and phasic muscle of young Korean adults

    An, Ho Jung; Choi, Wan Suk; Choi, Jung Hyun; Kim, Nyeon Jun; Min, Kyung Ok

    2015-01-01

    [Purpose] The aim of this study was to examine the effects of muscle activity and the number of resistance exercise repetitions on perceived exertion in tonic and phasic muscles in young Korean adults. [Subjects] Janda’s classification system was used to divide 40 Korean males and females in their 20s into a tonic muscle group (10 males, 10 females) and phasic muscle group (10 males, 10 females). [Methods] Each participant performed resistance exercise at 70% of maximum exertion for a single ...

  18. Kinaesthetic activities in physics instruction

    Bruun, Jesper; Voetmann Christiansen, Frederik

    2015-01-01

    One of the major difficulties in learning physics is for students to develop a conceptual understanding of the core concepts of physics. Many authors argue that students’ conceptions of basic physical phenomena are rooted in basic schemas, originating in fundamental kinaesthetic experiences of...... being. We argue that this idea should be utilized in physics instruction, that kinaesthetic activities will provide useful entry point for students’ acquisition of the basic conceptions of physics, and that they can overcome the phenomenological gap between experiential and conceptual understanding. We...... discuss the nature of image schemas and focus particularly on one: effort-resistance-flow. This schema is fundamental not only in our everyday experience, but also in most of school physics. We show how enactment of a particular kinaesthetic model can support student understanding and intuition with...

  19. Kinaesthetic activities in physics instruction

    Bruun, Jesper; Voetmann Christiansen, Frederik

    2016-01-01

    One of the major difficulties in learning physics is for students to develop a conceptual understanding of the core concepts of physics. Many authors argue that students’ conceptions of basic physical phenomena are rooted in basic schemas, originating in fundamental kinaesthetic experiences...... of being. We argue that this idea should be utilized in physics instruction, that kinaesthetic activities will provide useful entry point for students’ acquisition of the basic conceptions of physics, and that they can overcome the phenomenological gap between experiential and conceptual understanding. We...... discuss the nature of image schemas and focus particularly on one: effort-resistance-flow. This schema is fundamental not only in our everyday experience, but also in most of school physics. We show how enactment of a particular kinaesthetic model can support student understanding and intuition...

  20. Vaticaffinol, a resveratrol tetramer, exerts more preferable immunosuppressive activity than its precursor in vitro and in vivo through multiple aspects against activated T lymphocytes

    Feng, Li-Li; Wu, Xue-Feng; Liu, Hai-Liang; Guo, Wen-Jie; Luo, Qiong; Tao, Fei-Fei; Ge, Hui-Ming; Shen, Yan; Tan, Ren-Xiang; Xu, Qiang, E-mail: molpharm@163.com; Sun, Yang, E-mail: yangsun@nju.edu.cn

    2013-03-01

    In the present study, we aimed to investigate the immunosuppressive activity of vaticaffinol, a resveratrol tetramer isolated from Vatica mangachapoi, on T lymphocytes both in vitro and in vivo, and further explored its potential molecular mechanism. Resveratrol had a wide spectrum of healthy beneficial effects with multiple targets. Interestingly, its tetramer, vaticaffinol, exerted more intensive immunosuppressive activity than resveratrol. Vaticaffinol significantly inhibited T cells proliferation activated by concanavalin A (Con A) or anti-CD3 plus anti-CD28 in a dose- and time-dependent manner. It also induced Con A-activated T cells undergoing apoptosis through mitochondrial pathway. Moreover, this compound prevented cells from entering S phase and G2/M phase during T cells activation. In addition, vaticaffinol inhibited ERK and AKT signaling pathways in Con A-activated T cells. Furthermore, vaticaffinol significantly ameliorated ear swelling in a mouse model of picryl chloride-induced ear contact dermatitis in vivo. In most of the aforementioned experiments, however, resveratrol had only slight effects on the inhibition of T lymphocytes compared with vaticaffinol. Taken together, our findings suggest that vaticaffinol exerts more preferable immunosuppressive activity than its precursor resveratrol both in vitro and in vivo by affecting multiple targets against activated T cells. - Graphical abstract: Vaticaffinol, a resveratrol tetramer isolated from Vatica mangachapoi, exerts more intensive immunosuppressive activity than its precursor resveratrol does in vitro and in vivo. Its mechanism may involve multiple effects against activated T cells: regulation of signalings involved in cell proliferation, G0/G1 arrest of T cells, as well as an apoptosis induction in activated effector T cells. Highlights: ► Vaticaffinol, a resveratrol tetramer, exerts more potent activity than its precursor. ► It inhibited T cells proliferation and prevented them from entering

  1. Mechanisms of antimicrobial activity of physical agents

    Among numerous physical agents exerting their deleterious effect on microorganisms only a few have been applied to sterilization or disinfection used for medical purposes. Temperature is the most important agent, which from one side in a very wide range enables supporting of metabolic processes of psychro-, mezo- and thermophilic microorganisms, but beyond these limits causes their death. High temperature induces at first damages of cytoplasmic membrane and then denaturation of RNA leading to death. In the other hand, a low temperature slowly decreasing bellow 0oC induces crystallization of water in cells and destruction of cytoplasmic structures. Ultraviolet radiation causes mutations resulting in stopping of DNA replication in all forms of the microorganisms. The same way of the lethal activity is exerted by ionizing radiation. Its kinetic energy induces mutations affecting not single bases but also whole operons making gene expression impossible. Gaseous plasma is a new physical agent applied recently to sterilization. High frequency energy initiates generation of the plasma from hydrogen peroxide vapours in a high vacuum and creates reactive species particles from the vapours that collide and kill microorganisms. On the other hand, application of ultrasound radiation to killing of microorganisms needs for further studies because of a high variability depending upon used frequency and energy. It is not known, for example, if destruction of microorganisms by ultrasounds is related to a phenomenon of cavitation or thermal energy. Nevertheless, even a range of frequency and energy used in commercial microwave ovens kills vegetative cells of coliform rods in about 15 minutes. (author)

  2. Neuro-hormonal effects of physical activity in the elderly

    GiuseppeRengo; ClaudioDe Lucia

    2013-01-01

    Thanks to diagnostic and therapeutic advances, the elderly population is continuously increasing in the western countries. Accordingly, the prevalence of most chronic age-related diseases will increase considerably in the next decades, thus it will be necessary to implement effective preventive measures to face this epidemiological challenge. Among those, physical activity exerts a crucial role, since it has been proven to reduce the risk of cardiovascular diseases, diabetes, obesity, cogniti...

  3. Strategies to Increase Physical Activity

    Tuso, Phillip

    2015-01-01

    One key intervention to prevent preventable diseases and to make health care more affordable is to increase the percentage of Americans who are physically active. No single intervention will increase activity rates, but a group of interventions working together in synergy may be the stimulus needed to get Americans moving.

  4. Stress hormones and physical activity

    Editorial Office

    1991-01-01

    Hormone secretion during physical activity of specific duration and intensity is part of the stress response. In a study to investigate the secretion of ß-endorphin, leucine enkephalin and other recognised stress hormones during physical exercise, blood samples were taken from fourteen (14) healthy, male athletes who competed in a 21 km roadrace. Blood samples were collected before and after completion of the race. This study shows that ß-endorphin/ß-lipotropin, leucine enkephalin, prolact...

  5. Potential Moderators of Physical Activity on Brain Health

    Regina L. Leckie

    2012-01-01

    Full Text Available Age-related cognitive decline is linked to numerous molecular, structural, and functional changes in the brain. However, physical activity is a promising method of reducing unfavorable age-related changes. Physical activity exerts its effects on the brain through many molecular pathways, some of which are regulated by genetic variants in humans. In this paper, we highlight genes including apolipoprotein E (APOE, brain derived neurotrophic factor (BDNF, and catechol-O-methyltransferase (COMT along with dietary omega-3 fatty acid, docosahexaenoic acid (DHA, as potential moderators of the effect of physical activity on brain health. There are a growing number of studies indicating that physical activity might mitigate the genetic risks for disease and brain dysfunction and that the combination of greater amounts of DHA intake with physical activity might promote better brain function than either treatment alone. Understanding whether genes or other lifestyles moderate the effects of physical activity on neurocognitive health is necessary for delineating the pathways by which brain health can be enhanced and for grasping the individual variation in the effectiveness of physical activity interventions on the brain and cognition. There is a need for future research to continue to assess the factors that moderate the effects of physical activity on neurocognitive function.

  6. [Physical activity and cardiovascular health].

    Temporelli, Pier Luigi

    2016-03-01

    It is well known that regular moderate physical activity, in the context of a healthy lifestyle, significantly reduces the likelihood of cardiovascular events, both in primary and secondary prevention. In addition, it is scientifically proven that exercise can reduce the incidence of diabetes, osteoporosis, depression, breast cancer and colon cancer. Despite this strong evidence, sedentary lifestyle remains a widespread habit in the western world. Even in Italy the adult population has a poor attitude to regular physical activity. It is therefore necessary, as continuously recommended by the World Health Organization, to motivate people to "move" since the transition from inactivity to regular light to moderate physical activity has a huge impact on health, resulting in significant savings of resources. We do not need to be athletes to exercise - it should be part of all our daily routines. PMID:27029874

  7. Motivating People To Be Physically Active. Physical Activity Intervention Series.

    Marcus, Bess H.; Forsyth, LeighAnn H.

    This book describes proven methods for helping people change from inactive to active living. The behavior change methods are useful for healthy adults as well as individuals with chronic physical and psychological conditions. The book describes intervention programs for individuals and groups and for workplace and community settings. Part 1,…

  8. FastStats: Exercise or Physical Activity

    ... What's this? Submit Button NCHS Home Exercise or Physical Activity Recommend on Facebook Tweet Share Compartir Data are ... years of age and over who met the Physical Activity Guidelines for aerobic physical activity: 49.2% Percent ...

  9. Ginsenoside Rp1 Exerts Anti-inflammatory Effects via Activation of Dendritic Cells and Regulatory T Cells.

    Bae, Jingyu; Koo, Jihye; Kim, Soochan; Park, Tae-Yoon; Kim, Mi-Yeon

    2012-10-01

    Ginsenoside Rp1 (G-Rp1) is a saponin derivate that provides anti-metastatic activities through inhibition of the NF-κB pathway. In this study, we examined the effects of G-Rp1 on regulatory T cell (Treg) activation. After treatment of splenocytes with G-Rp1, Tregs exhibited upregulation of IL-10 expression, and along with dendritic cells (DCs), these Tregs showed increased cell number compared to other cell populations. The effect of G-Rp1 on Treg number was augmented in the presence of lipopolysaccharide (LPS), which mimics pathological changes that occur during inflammation. However, depletion of DCs prevented the increase in Treg number in the presence of G-Rp1 and/or LPS. In addition, G-Rp1 promoted the differentiation of the memory types of CD4(+)Foxp3(+)CD62L(low) Tregs rather than the generation of new Tregs. In vivo experiments also demonstrated that Tregs and DCs from mice that were fed G-Rp1 for 7 d and then injected with LPS exhibited increased activation compared with those from mice that were injected with LPS alone. Expression of TGF-β and CTLA4 in Tregs was increased, and upregulation of IL-2 and CD80/ CD86 expression by DCs affected the suppressive function of Tregs through IL-2 receptors and CTLA4. These data demonstrate that G-Rp1 exerts anti-inflammatory effects by activating Tregs in vitro and in vivo. PMID:23717139

  10. Physical Activity in the Classroom

    Réol, Lise Andersen

    2016-01-01

    activities in school enhance positive emotions and support an inclusive and safe learning environment. Thought it does also point to the fact, that it is indeed not that simple. Teachers’ sport-specific educational competences, their own experience of well-being and fun related to physical activities and......It is a wide held belief among scientist and teachers that physical activities in school creates joyfulness and supports the development of a ‘positive’ learning environment. This belief is solid, but built on scant scientific documentation. In Denmark new governmental policy prescribes 45 minutes...... their ability to align activities to the specific group of children they teach, seems to influence the joy and positive effects on the learning environment in school....

  11. Stress hormones and physical activity

    Editorial Office

    1991-07-01

    Full Text Available Hormone secretion during physical activity of specific duration and intensity is part of the stress response. In a study to investigate the secretion of ß-endorphin, leucine enkephalin and other recognised stress hormones during physical exercise, blood samples were taken from fourteen (14 healthy, male athletes who competed in a 21 km roadrace. Blood samples were collected before and after completion of the race. This study shows that ß-endorphin/ß-lipotropin, leucine enkephalin, prolactin, and melatonin may be classified as stress hormones in physical activity of duration 80 to 120 minutes and intensity exceeding 75%-V0₂max. Widespread intra-individual variation in serum cortisol concentrations prevent definite conclusion. The un­expected increase in serum testosterone levels warrants further research.

  12. Evaluation of the physical forces exerted on a spherical bubble inside the nozzle in a cavitating flow with an Eulerian/Lagrangian approach

    Javad Zeidi, Seyed Mohammad; Mahdi, Miralam

    2015-11-01

    An Eulerian/Lagrangian approach is used to calculate the physical forces acting on a spherical bubble. Reynolds average Navier-Stokes (RANS) equations for the Eulerian approach are solved with a finite volume scheme. The SIMPLE algorithm is utilized for pressure and velocity linkage. To model convective fluxes, an upwind scheme is used. The Reynolds stress transport model (RSTM) is used to calculate the turbulent parameters. In the Lagrangian approach, a modified form of the Reyleigh-Plesset (RP) and Maxey equations are solved with MATLAB programming software for evaluation of bubble motion and bubble dynamics. The carrying fluid in this study is diesel fuel. Continuous filter white noise (CFWN) is solved parallel to the Maxey and RP equations to calculate fluctuating terms of velocity in x and y directions. Six forces exerted on the bubble during its motion are investigated inside the cavitating flow regime. The cavitating regime can be extremely effective on bubble force and increase bubble forces up to several thousand times. Added mass force in the y direction has the highest value among all forces exerted on the bubble during its motion inside the nozzle.

  13. Physical activity, hydration and health

    Ascensión Marcos

    2014-06-01

    Full Text Available Since the beginning of mankind, man has sought ways to promote and preserve health as well as to prevent disease. Hydration, physical activity and exercise are key factors for enhancing human health. However, either a little dose of them or an excess can be harmful for health maintenance at any age. Water is an essential nutrient for human body and a major key to survival has been to prevent dehydration. However, there is still a general controversy regarding the necessary amount to drink water or other beverages to properly get an adequate level of hydration. In addition, up to now the tools used to measure hydration are controversial. To this end, there are several important groups of variables to take into account such as water balance, hydration biomarkers and total body water. A combination of methods will be the most preferred tool to find out any risk or situation of dehydration at any age range. On the other hand, physical activity and exercise are being demonstrated to promote health, avoiding or reducing health problems, vascular and inflammatory diseases and helping weight management. Therefore, physical activity is also being used as a pill within a therapy to promote health and reduce risk diseases, but as in the case of drugs, dose, intensity, frequency, duration and precautions have to be evaluated and taken into account in order to get the maximum effectiveness and success of a treatment. On the other hand, sedentariness is the opposite concept to physical activity that has been recently recognized as an important factor of lifestyle involved in the obesogenic environment and consequently in the risk of the non-communicable diseases. In view of the literature consulted and taking into account the expertise of the authors, in this review a Decalogue of global recommendations is included to achieve an adequate hydration and physical activity status to avoid overweight/obesity consequences.

  14. Scoparone Exerts Anti-Tumor Activity against DU145 Prostate Cancer Cells via Inhibition of STAT3 Activity

    Kim, Jeong-Kook; Kim, Joon-Young; Kim, Han-Jong; Park, Keun-Gyu; Harris, Robert A.; Cho, Won-Jea; Lee, Jae-Tae; Lee, In-Kyu

    2013-01-01

    Scoparone, a natural compound isolated from Artemisia capillaris, has been used in Chinese herbal medicine to treat neonatal jaundice. Signal transducer and activator of transcription 3 (STAT3) contributes to the growth and survival of many human tumors. This study was undertaken to investigate the anti-tumor activity of scoparone against DU145 prostate cancer cells and to determine whether its effects are mediated by inhibition of STAT3 activity. Scoparone inhibited proliferation of DU145 ce...

  15. Youth Physical Activity Resources Use and Activity Measured by Accelerometry

    Maslow, Andréa L.; Colabianchi, Natalie

    2014-01-01

    Objectives To examine whether utilization of physical activity resources (eg, parks) was associated with daily physical activity measured by accelerometry. Methods 111 adolescents completed a travel diary with concurrent accelerometry. The main exposure was self-reported utilization of a physical activity resource (none/1+ resources). The main outcomes were total minutes spent in daily 1) moderate-vigorous physical activity and 2) vigorous physical activity. Results Utilizing a physical activity resource was significantly associated with total minutes in moderate-vigorous physical activity. African-Americans and males had significantly greater moderate-vigorous physical activity. Conclusions Results from this study support the development and use of physical activity resources. PMID:21204684

  16. The physical therapist's role in physical activity promotion

    Verhagen, E.; Engbers, L.

    2009-01-01

    Clinicians are increasingly confronted with the diseases of physical inactivity. Paradoxically, a promising strategy to motivate sedentary individuals to become more active is the opportunity to encourage physical activity related behavioural change when individuals encounter health professionals. A

  17. Physical and Social Contexts of Physical Activities Among Adolescent Girls

    Kuo, JoAnn; Schmitz, Kathryn H.; Evenson, Kelly R.; McKenzie, Thomas L.; Jobe, Jared B.; Rung, Ariane L.; Gittelsohn, Joel; Pate, Russell R.

    2016-01-01

    Background With limited opportunities for physical activity during school hours, it is important to understand the contexts of physical activities done outside of school time. Given the importance of physical and social aspects of environments, the purpose of this study was to describe where and with whom girls participate in physical activities outside of school. Methods Participants were 1925 sixth-grade girls in the Trial of Activity for Adolescent Girls (TAAG). At baseline, they completed a 3-day physical activity recall (3DPAR), reporting the main activity performed during 30-minute intervals and the physical and social contexts of physical activities. Results The most frequently reported physical activities done outside of school time were house chores, walking (for transportation or exercise), dance, basketball, playing with younger children, and running or jogging. The most common location for these activities was at home or in the neighborhood. With the exception of household chores, these activities were typically done with at least one other person. Conclusions Interventions that promote physical activities that can be done at or around home or developing supportive social networks for physical activity would be consistent with the current physical activity contexts of adolescent girls. PMID:19420391

  18. PHYSICAL DISABILITY AND DRAMA ACTIVITY

    KRAJNC JOLDIKJ Suzana

    2008-01-01

    Drama activity presents a great challenge for ado­lescents with physical disabilities, and at the same time it provides them with much experience for life.Adolescents are educated through theatrical activ­ity; they test numerous new roles, develop their attitude towards the art culture, and most of all they get the insight into different life situations, which have not been known to many of them so far. By experiencing different roles, an adolescent gets personal recognition, undergoes a proc...

  19. Estimated times to exhaustion and power outputs at the gas exchange threshold, physical working capacity at the rating of perceived exertion threshold, and respiratory compensation point.

    Bergstrom, Haley C; Housh, Terry J; Zuniga, Jorge M; Camic, Clayton L; Traylor, Daniel A; Schmidt, Richard J; Johnson, Glen O

    2012-10-01

    The purposes of this study were to compare the power outputs and estimated times to exhaustion (T(lim)) at the gas exchange threshold (GET), physical working capacity at the rating of perceived exertion threshold (PWC(RPE)), and respiratory compensation point (RCP). Three male and 5 female subjects (mean ± SD: age, 22.4 ± 2.8 years) performed an incremental test to exhaustion on an electronically braked cycle ergometer to determine peak oxygen consumption rate, GET, and RCP. The PWC(RPE) was determined from ratings of perceived exertion data recorded during 3 continuous workbouts to exhaustion. The estimated T(lim) values for each subject at GET, PWC(RPE), and RCP were determined from power curve analyses (T(lim) = ax(b)). The results indicated that the PWC(RPE) (176 ± 55 W) was not significantly different from RCP (181 ± 54 W); however, GET (155 ± 42 W) was significantly less than PWC(RPE) and RCP. The estimated T(lim) for the GET (26.1 ± 9.8 min) was significantly greater than PWC(RPE) (14.6 ± 5.6 min) and RCP (11.2 ± 3.1 min). The PWC(RPE) occurred at a mean power output that was 13.5% greater than the GET and, therefore, it is likely that the perception of effort is not driven by the same mechanism that underlies the GET (i.e., lactate buffering). Furthermore, the PWC(RPE) and RCP were not significantly different and, therefore, these thresholds may be associated with the same mechanisms of fatigue, such as increased levels of interstitial and (or) arterial [K⁺]. PMID:22716291

  20. Ways optimization physical activity students

    Vasilij Sutula

    2014-12-01

    Full Text Available Purpose: on the basis of the analysis of results of poll of students, first, to define structure and the importance of the factors influencing formation of motivation at them to sports and sports activity, secondly, to allocate possible subjects for extension of the maintenance of theoretical and methodical-practical components of sports formation of student's youth. Material and Methods: the study involved students of first and second courses of the Institute for training bodies and the Faculty of Law of the National University №9 Yaroslav the Wise and the students of the Kyiv National University of Culture and Arts and Zhytomyr State University named after Ivan Franko. Results: it is established that during training at national law university interests of students concerning factors which motivate them to sports and sports activity significantly change. The analyses data testify that a key factor which prevents students to be engaged in sports and sports activity, lack of free time is. It is proved that students consider necessary to receive information on the physical state. Conclusions: results of research allowed allocating the most significant factors which motivate students to be engaged in sports and sports activity. It is established subjects of theoretical and methodical and practical components of sports education which interest students of NLU and KNUCA and ZSU. It is shown that for students of Law University of importance topic of theoretical and methodological and practical components of physical education strongly depends on the year of their training.

  1. Macronutrient Intake for Physical Activity

    Buford, Thomas

    Proper nutrition is an essential element of athletic performance, body composition goals, and general health. Although natural variability among persons makes it impossible to create a single diet that can be recommended to all; examining scientific principles makes it easier for athletes and other physically active persons to eat a diet that prepares them for successful training and/or athletic competition. A proper nutritional design incorporates these principles and is tailored to the individual. It is important for the sports nutritionist, coach, and athlete to understand the role that each of the macronutrients plays in an active lifestyle. In addition, keys to success include knowing how to determine how many calories to consume, the macronutrient breakdown of those calories, and proper timing to maximize the benefits needed for the individual's body type and activity schedule.

  2. Occupational and leisure time physical activity

    Holtermann, Andreas; Marott, Jacob Louis; Gyntelberg, Finn;

    2012-01-01

    Men with low physical fitness and high occupational physical activity are recently shown to have an increased risk of cardiovascular disease and all-cause mortality. The association between occupational physical activity with cardiovascular disease and all-cause mortality may also depend on leisure...... time physical activity....

  3. ATTITUDES TOWARD PHYSICAL ACTIVITY AND ITS MEASUREMENT

    VISHNU PETHKAR; SHRADDHA NAIK; SANJEEV SONAWANE

    2010-01-01

    This paper is based on the fact, experience and concerns of many physical educators & teachers about the severe decline in levels of physical activity and the ways in which, incorporation & teaching of physical activity is carried out. This paper deals with the theoretical psychological basis of physical activity andinterventions carried out in measurement of this dimension. This paper tries to bring out the relevance of psychological determinants of physical activity and how these need to su...

  4. The Evolution of Physical Activity Promotion

    Richards, Elizabeth

    2015-01-01

    Overview: A physically active lifestyle has numerous physical and mental health benefits for patients of all ages. Despite these significant benefits, a majority of Americans do not meet current physical activity guidelines. Health care providers, especially nurses, play a vital role in physical activity promotion. Over the past several decades, exercise and physical activity guidelines have evolved from a focus on structured, vigorous exercise to a focus on moderate-intensity “lifestyle” phy...

  5. Physical activity: the present in the context of the past.

    Malina, Robert M; Little, Bertis B

    2008-01-01

    In the broad sense, modern humans have lived in an environment in which physical activity and associated movement skills were central, especially in the context of physical competition with other animals. The physically active lifestyle of earlier human populations has been emphasized, especially the cardiovascular endurance component and energy expenditure, but less attention has been devoted to the gross and fine motor skills that are essential components of this lifestyle. Motor skills developed through practice are important determinants of success and survival in preindustrial societies. In industrial and postindustrial societies, on the other hand, the role of physical activity is different, with prowess in certain areas of physical expertise (e.g., accuracy with projectiles, muscular strength, among others) and prolonged exertion (i.e., cardiovascular endurance) less important for survival. The combined effects of the transition to a sedentary lifestyle and attendant dietary changes have resulted first an epidemic of coronary heart disease and more recently an epidemic of overweight/obesity in postindustrial societies. Although mortality associated with coronary heart disease has declined, due largely to biomedical advances, overweight and obesity have increased concomitantly with population reduction in physical activity (energy expenditure) and increased calorie (energy) consumption. The current scenario begs several questions which have implications for contemporary human biology related to sustaining the pace of cultural change on a biological base that is increasingly being compromised by physical inactivity, overweight, and obesity. PMID:18433002

  6. Childhood asthma and physical activity

    Lochte, Lene; Nielsen, Kim G; Petersen, Poul Erik;

    2016-01-01

    BACKGROUND: Childhood asthma is a global problem affecting the respiratory health of children. Physical activity (PA) plays a role in the relationship between asthma and respiratory health. We hypothesized that a low level of PA would be associated with asthma in children and adolescents. The...... objectives of our study were to (1) summarize the evidence available on associations between PA and asthma prevalence in children and adolescents and (2) assess the role of PA in new-onset or incident asthma among children and adolescents. METHODS: We searched Medline, the Cochrane Library, and Embase and......42014013761; available at: http://www.crd.york.ac.uk/PROSPERO [accessed: 24 March 2016])....

  7. Physics of Space Plasma Activity

    This book provides a timely review of our present understanding of plasma phenomena in magnetized terrestrial and solar space plasmas. The author's emphasis is on the fluid and particle modeling and interpretation of observed active processes in space plasmas, i.e. 'the physical background of large plasma eruptions in space'. It is somewhat alarming for a plasma physicist to read that an emphasis on processes in spatially inhomogeneous plasmas means that the work '... excludes a considerable fraction of the available methods in space plasma physics, such as the theory of waves, instabilities and wave particle interactions on a homogeneous background', particularly in light of the fact that much of our knowledge of these plasmas is derived from observations of such waves. However, it is clear on reading the book that such a restriction is not a disadvantage, but allows the author to concentrate on the main theme of the book, namely the use of fluid and particle pictures to model the equilibrium and active states of space plasmas. There are many other books which cover the wave aspects of space plasmas, and would complement this book. The book's coverage is based on the extensive and profound research of the author and his colleagues in the area of fluid and particle modeling of space plasma structures. After an introduction to the physical setting of active plasmas, and a necessarily concise, but effective, discussion of the fluid and particle models to be used, the steady states of the magnetized plasmas of interest are treated, including the magnetosphere, solar plasmas and current sheets. Next the dynamics of unstable states is covered, including MHD and tearing instabilities, and nonlinear aspects, with a detailed discussion of magnetic reconnection. Finally, the models are applied to magnetospheric and solar observations. The book is attractively written and produced, and this reviewer managed to find a minimum number of errors. A particularly attractive

  8. PHYSICAL DISABILITY AND DRAMA ACTIVITY

    Suzana KRAJNC JOLDIKJ

    2008-06-01

    Full Text Available Drama activity presents a great challenge for ado­lescents with physical disabilities, and at the same time it provides them with much experience for life.Adolescents are educated through theatrical activ­ity; they test numerous new roles, develop their attitude towards the art culture, and most of all they get the insight into different life situations, which have not been known to many of them so far. By experiencing different roles, an adolescent gets personal recognition, undergoes a process of personal changing and thus tests his or her per­sonal perceptions of life.As regards drama activity we follow the presump­tion saying that being different is also an advan­tage.The main purpose of the drama activity is gradu­ally realized through the programme: getting to know yourself and the theatre medium in general. Adolescents meet the multilayered communication and public appearance, which helps them in their personal life.

  9. 体育教学中如何运用情感教育%How to Exert Emotional Education in Physical Education

    王建勋

    2011-01-01

    《体育新课程标准》提出“要强调在体育教学中“睛意’与‘认知’相统一的重要性,进行情感教育。”本文从热爱学生、结合教学内容、营造课堂氛围以及培养学生自信心等几方面探究情感教育在体育教学中的运用策略。%It is laid down in the new standard for PE course that it should be put in the important position to lay stress on the integration of emotion and recognition in physical education.This paper inquires into the strategy for the exertion of emotional ed- ucation from the following aspects: to love students, to relate teaching contents,to build class atmosphere and so on.

  10. Physical Activity during the School Day

    Castelli, Darla M.; Ward, Kimberly

    2012-01-01

    In response to concerns that children are physically inactive, a Centers for Disease Control and Prevention committee developed school-based implementation strategies centered on the components of a Comprehensive School Physical Activity Program (CSPAP), composed of the physical education program, physical activity during the school day, staff…

  11. Physical Activity and Health in Preschool Children

    Christensen, Line Brinch

    Physical activity is beneficial in relation to several life style diseases and the association between physical activity and early predictors of life style diseases seem to be present already in preschool age. Since physical activity and other health behaviours are established during childhood and...... track from childhood into adult life, it is relevant to address physical activity already in the preschool age. The research in preschool children’s physical activity is relatively new, and because of methodological inconsistencies, the associations between physical activity and health are less clear in...... this age group. The objective of this thesis was to contribute to the knowledge base regarding physical activity in preschoolers; How active are preschoolers? Are activity levels related to specific settings during a typical week? And are the activity levels related to a range of health outcomes...

  12. Spontaneous Physical Activity Downregulates Pax7 in Cancer Cachexia

    Dario Coletti

    2016-01-01

    Full Text Available Emerging evidence suggests that the muscle microenvironment plays a prominent role in cancer cachexia. We recently showed that NF-kB-induced Pax7 overexpression impairs the myogenic potential of muscle precursors in cachectic mice, suggesting that lowering Pax7 expression may be beneficial in cancer cachexia. We evaluated the muscle regenerative potential after acute injury in C26 colon carcinoma tumor-bearing mice and healthy controls. Our analyses confirmed that the delayed muscle regeneration observed in muscles form tumor-bearing mice was associated with a persistent local inflammation and Pax7 overexpression. Physical activity is known to exert positive effects on cachectic muscles. However, the mechanism by which a moderate voluntary exercise ameliorates muscle wasting is not fully elucidated. To verify if physical activity affects Pax7 expression, we hosted control and C26-bearing mice in wheel-equipped cages and we found that voluntary wheel running downregulated Pax7 expression in muscles from tumor-bearing mice. As expected, downregulation of Pax7 expression was associated with a rescue of muscle mass and fiber size. Our findings shed light on the molecular basis of the beneficial effect exerted by a moderate physical exercise on muscle stem cells in cancer cachexia. Furthermore, we propose voluntary exercise as a physiological tool to counteract the overexpression of Pax7 observed in cancer cachexia.

  13. Spontaneous Physical Activity Downregulates Pax7 in Cancer Cachexia.

    Coletti, Dario; Aulino, Paola; Pigna, Eva; Barteri, Fabio; Moresi, Viviana; Annibali, Daniela; Adamo, Sergio; Berardi, Emanuele

    2016-01-01

    Emerging evidence suggests that the muscle microenvironment plays a prominent role in cancer cachexia. We recently showed that NF-kB-induced Pax7 overexpression impairs the myogenic potential of muscle precursors in cachectic mice, suggesting that lowering Pax7 expression may be beneficial in cancer cachexia. We evaluated the muscle regenerative potential after acute injury in C26 colon carcinoma tumor-bearing mice and healthy controls. Our analyses confirmed that the delayed muscle regeneration observed in muscles form tumor-bearing mice was associated with a persistent local inflammation and Pax7 overexpression. Physical activity is known to exert positive effects on cachectic muscles. However, the mechanism by which a moderate voluntary exercise ameliorates muscle wasting is not fully elucidated. To verify if physical activity affects Pax7 expression, we hosted control and C26-bearing mice in wheel-equipped cages and we found that voluntary wheel running downregulated Pax7 expression in muscles from tumor-bearing mice. As expected, downregulation of Pax7 expression was associated with a rescue of muscle mass and fiber size. Our findings shed light on the molecular basis of the beneficial effect exerted by a moderate physical exercise on muscle stem cells in cancer cachexia. Furthermore, we propose voluntary exercise as a physiological tool to counteract the overexpression of Pax7 observed in cancer cachexia. PMID:27034684

  14. Congenital Heart Defects and Physical Activity

    ... Tools & Resources Stroke More Congenital Heart Defects and Physical Activity Updated:Apr 19,2016 Exercise Is for Everyone ... almost all patients do some form of regular physical activity. There are a few exceptions, so it's good ...

  15. Promoting physical activity in socially vulnerable groups

    Herens, M.C.

    2016-01-01

    Background:  In the Netherlands, inequalities in physical activity behaviour go hand in hand with socioeconomic inequalities in health. To promote physical activity effectively and equitably, participatory community-based physical activity interventions seem promising and are supported by the Dutch government’s policy. Although many strategies have been developed to increase physical activity levels in general and in socially vulnerable groups in particular, most evaluations show o...

  16. Exposure to Air Pollutants During Physical Activity

    Ramos, C.A.

    2016-01-01

    The context for this thesis is the concern that people who practice physical activity are more susceptible to air pollution. For the studies presented here, three perspectives of physical activity were considered: in indoor, i) physical activity in fitness centers; in outdoor ii) the use of bicycle

  17. Putting Physical Activity on the Policy Agenda

    Woods, Catherine B.; Mutrie, Nanette

    2012-01-01

    The purpose of this paper is to outline why physical activity policy is important in terms of promoting population based increases in physical activity. The promotion of physical activity through public policy happens globally and nationally, however to be successful it should also happen at state and local levels. We outline the rationale for the…

  18. Evaluating a Model of Youth Physical Activity

    Heitzler, Carrie D.; Lytle, Leslie A.; Erickson, Darin J.; Barr-Anderson, Daheia; Sirard, John R.; Story, Mary

    2010-01-01

    Objective: To explore the relationship between social influences, self-efficacy, enjoyment, and barriers and physical activity. Methods: Structural equation modeling examined relationships between parent and peer support, parent physical activity, individual perceptions, and objectively measured physical activity using accelerometers among a…

  19. Promoting physical activity in socially vulnerable groups

    Herens, M.C.

    2016-01-01

    Background:  In the Netherlands, inequalities in physical activity behaviour go hand in hand with socioeconomic inequalities in health. To promote physical activity effectively and equitably, participatory community-based physical activity interventions seem promising and are s

  20. Crocin exerts anti-inflammatory and anti-catabolic effects on rat intervertebral discs by suppressing the activation of JNK

    Li, Kang; Li, Yan; MA, ZHENJIANG; Zhao, Jie

    2015-01-01

    As intervertebral disc (IVD) degeneration has been proven to contribute to low back pain (LBP), drug treatment aiming at attenuating IVD degeneration may prove to be benefiical. Crocin, a bioactive component of saffron, has been found to exert anti-inflammatory effects on cartilage. In the present study, the anti-inflammatory and anti-catabolic effects of crocin on rat IVDs were analyzed in vitro and ex vivo. Nucleus pulposus (NP) cells were isolated from the lumbar IVDs of Sprague-Dawley rat...

  1. Physical Education and Physical Activity: A Historical Perspective

    Guedes, Claudia

    2007-01-01

    Although many recent studies have shown that the lack of physical activity is one of the major causes of obesity, diabetes, and cardiovascular disease among children and adolescents, few studies have shown the connection between the lack of physical education and the prevalence of a sedentary lifestyle. However, it is clear that physical education…

  2. Inhibition of Hypoxia Inducible Factor Alpha and Astrocyte-Elevated Gene-1 Mediates Cryptotanshinone Exerted Antitumor Activity in Hypoxic PC-3 Cells

    Hyo-Jeong Lee

    2012-01-01

    Full Text Available Although cryptotanshinone (CT was known to exert antitumor activity in several cancers, its molecular mechanism under hypoxia still remains unclear. Here, the roles of AEG-1 and HIF-1α in CT-induced antitumor activity were investigated in hypoxic PC-3 cells. CT exerted cytotoxicity against prostate cancer cells and suppressed HIF-1α accumulation and AEG-1 expression in hypoxic PC-3 cells. Also, AEG-1 was overexpressed in prostate cancer cells. Interestingly, HIF-1α siRNA transfection enhanced the cleavages of caspase-9,3, and PAPR and decreased expression of Bcl-2 and AEG1 induced by CT in hypoxic PC-3 cells. Of note, DMOG enhanced the stability of AEG-1 and HIF-1α during hypoxia. Additionally, CT significantly reduced cellular level of VEGF in PC-3 cells and disturbed tube formation of HUVECs. Consistently, ChIP assay revealed that CT inhibited the binding of HIF-1α to VEGF promoter. Furthermore, CT at 10 mg/kg suppressed the growth of PC-3 cells in BALB/c athymic nude mice by 46.4% compared to untreated control. Consistently, immunohistochemistry revealed decreased expression of Ki-67, CD34, VEGF, carbonic anhydrase IX, and AEG-1 indices in CT-treated group compared to untreated control. Overall, our findings suggest that CT exerts antitumor activity via inhibition of HIF-1α, AEG1, and VEGF as a potent chemotherapeutic agent.

  3. Practical Approaches to Prescribing Physical Activity and Monitoring Exercise Intensity.

    Reed, Jennifer L; Pipe, Andrew L

    2016-04-01

    Regular physical activity helps to prevent heart disease, and reduces the risk of first or subsequent cardiovascular events. It is recommended that Canadian adults accumulate at least 150 minutes of moderate- to vigorous-intensity aerobic exercise per week, in bouts of 10 minutes or more, and perform muscle- and bone-strengthening activities at least 2 days per week. Individual exercise prescriptions can be developed using the frequency, intensity, time, and type principles. Increasing evidence suggests that high-intensity interval training is efficacious for a broad spectrum of heart health outcomes. Several practical approaches to prescribing and monitoring exercise intensity exist including: heart rate monitoring, the Borg rating of perceived exertion scale, the Talk Test, and, motion sensors. The Borg rating of perceived exertion scale matches a numerical value to an individual's perception of effort, and can also be used to estimate heart rate. The Talk Test, the level at which simple conversation is possible, can be used to monitor desired levels of moderate- to vigorous-intensity exercise. Motion sensors can provide users with practical and useful exercise training information to aid in meeting current exercise recommendations. These approaches can be used by the public, exercise scientists, and clinicians to easily and effectively guide physical activity in a variety of settings. PMID:26897182

  4. Physical Activity and Incidence of Atrial Fibrillation in Older Adults: The Cardiovascular Health Study

    Suneet Mittal, MD

    2008-01-01

    Retrospective case-control studies and case series of younger athletes and middle-aged adults have suggested an adverse association between physical activity and development of atrial fibrillation. However, these studies have evaluated subjects engaged in either vigorous exertion or endurance training. On the other hand, habitual physical activity might be expected through salutatory effects on blood pressure, vascular compliance, coronary disease, and heart failure to reduce the incidence of...

  5. Exergaming for Physical Activity in Online Physical Education

    Kooiman, Brian J.; Sheehan, Dwayne P.; Wesolek, Michael; Reategui, Eliseo

    2016-01-01

    For many the thought of students taking an online course conjures up images of students sitting at a computer desk. Students taking online physical education (OLPE) at home may lack opportunities for competitive or cooperative physical activity that are available to students in a traditional setting. Active video games (exergames) can be played…

  6. Physical education, school physical activity, school sports and academic performance

    Shephard Roy J.; Trudeau François

    2008-01-01

    Abstract Background The purpose of this paper is to review relationships of academic performance and some of its determinants to participation in school-based physical activities, including physical education (PE), free school physical activity (PA) and school sports. Methods Linkages between academic achievement and involvement in PE, school PA and sport programmes have been examined, based on a systematic review of currently available literature, including a comprehensive search of MEDLINE ...

  7. Activities report in nuclear physics

    Jansen, J. F. W.; Scholten, O.

    1987-01-01

    Experimental studies of giant resonances, nuclear structure, light mass systems, and heavy mass systems are summarized. Theoretical studies of nuclear structure, and dynamics are described. Electroweak interactions; atomic and surface physics; applied nuclear physics; and nuclear medicine are discus

  8. Telmisartan Exerts Anti-Tumor Effects by Activating Peroxisome Proliferator-Activated Receptor-γ in Human Lung Adenocarcinoma A549 Cells

    Juan Li

    2014-03-01

    Full Text Available Telmisartan, a member of the angiotensin II type 1 receptor blockers, is usually used for cardiovascular diseases. Recent studies have showed that telmisartan has the property of PPARγ activation. Meanwhile, PPARγ is essential for tumor proliferation, invasion and metastasis. In this work we explore whether telmisartan could exert anti-tumor effects through PPARγ activation in A549 cells. MTT and trypan blue exclusion assays were included to determine the survival rates and cell viabilities. RT-PCR and western blotting were used to analyze the expression of ICAM-1, MMP-9 and PPARγ. DNA binding activity of PPARγ was evaluated by EMSA. Our data showed that the survival rates and cell viabilities of A549 cells were all reduced by telmisartan in a time- and concentration-dependent manner. Meanwhile, our results also demonstrated that telmisartan dose-dependently inhibited the expression of ICAM-1 and MMP-9. Moreover, the cytotoxic and anti-proliferative effects, ICAM-1 and MMP-9 inhibitive properties of telmisartan were totally blunted by the PPARγ antagonist GW9662. Our findings also showed that the expression of PPARγ was up-regulated by telmisartan in a dose dependent manner. And, the EMSA results also figured out that DNA binding activity of PPARγ was dose-dependently increased by telmisartan. Additionally, our data also revealed that telmisartan-induced PPARγ activation was abrogated by GW9662. Taken together, our results indicated that telmisartan inhibited the expression of ICAM-1 and MMP-9 in A549 cells, very likely through the up-regulation of PPARγ synthesis.

  9. Annual report on nuclear physics activities

    This report surveys the activities in basic research from July 1, 1986 to June 30, 1987 at the Institute for Nuclear Physics (IK) of the Nuclear Research Center Karlsruhe. The research program of this institute comprises laser spectroscopy, nuclear reactions with light ions, neutron physics, neutrino physics and high energy physics, as well as detector technology. (orig.)

  10. Annual report on nuclear physics activities

    This report surveys the activities in fundamental research from July 1, 1981 to June 30, 1982 at the three institutes of the KfK which are concerned with nuclear physics. The research program comprises laser spectroscopy, nuclear reactions with light ions, neutron physics, neutrino physics and physics at medium and higher energies. (orig.)

  11. Does the benefit on survival from leisure time physical activity depend on physical activity at work?

    Holtermann, Andreas; Marott, Jacob Louis; Gyntelberg, Finn;

    2013-01-01

    To investigate if persons with high physical activity at work have the same benefits from leisure time physical activity as persons with sedentary work.......To investigate if persons with high physical activity at work have the same benefits from leisure time physical activity as persons with sedentary work....

  12. Exergaming: Syncing Physical Activity and Learning

    Hicks, Lisa; Higgins, John

    2010-01-01

    This article discusses exergaming, a groundbreaking type of video game which is creating a revolution in physical education. Exergaming combines physical activity and video gaming to create an enjoyable and appealing way for students to be physically active. An extremely popular choice in this genre is the music video/dance rhythm game (MVDG). One…

  13. Exergames: Increasing Physical Activity through Effective Instruction

    Rudella, Jennifer L.; Butz, Jennifer V.

    2015-01-01

    Due to the growing obesity epidemic in the United States, educators must consider new ways to increase physical activity in an effort to address obesity. There are a variety of ways educators can increase physical activity in the classroom, and exergames--video games that require physical movement in order to play--are a modern-day approach to…

  14. Physical activity and sleep among pregnant women

    Borodulin, Katja; Evenson, Kelly R; Monda, Keri; Wen, Fang; Herring, Amy H.; Dole, Nancy

    2010-01-01

    Sleep disturbances are common among pregnant women and safe treatments to improve sleep are needed. Generally, physical activity improves sleep, but studies are lacking on the associations of physical activity with sleep among pregnant women. Our aim was to investigate the cross-sectional association of various modes of physical activity and activity clusters with sleep quality and duration among 1259 pregnant women. Participants were recruited into the Pregnancy, Infection, and Nutrition Stu...

  15. Dynamic Activity-Related Incentives for Physical Activity.

    Schüler, Julia; Brunner, Sibylle

    2012-01-01

    The present studies adopted the theoretical framework of activity- and purpose-related incentives (Rheinberg, 2008) to explain the maintenance of physical activity. We hypothesized that activity-related incentives (e.g., “fun”) increase more than purpose-related incentives (e.g., “health”) between the initiation and maintenance phase of physical activity. Additionally, change in activity-related incentives was hypothesized to be a better predictor of maintenance of physical activity than chan...

  16. Dynamic activity-related incentives for physical activity

    2012-01-01

    The present studies adopted the theoretical framework of activity- and purpose-related incentives (Rheinberg, 2008) to explain the maintenance of physical activity. We hypothesized that activity-related incentives (e.g., “fun”) increase more than purpose-related incentives (e.g., “health”) between the initiation and maintenance phase of physical activity. Additionally, change in activity-related incentives was hypothesized to be a better predictor of maintenance of physical activity than chan...

  17. Physical activity in Greenland - a methodological perspective

    Dahl-Petersen, Inger

    Title: Physical activity in Greenland - a methodical perspective Inger Dahl-Petersen, National Institute of Public Health, Copenhagen, Denmark Purpose:   The present study is the first population-based study in Greenland with information on physical activity using The International Physical...... Participants in a cross-sectional population survey representative of towns and villages in West Greenland completed an interviewer-administered questionnaire about their physical activity. The long version of The International Physical Activity Questionnaire (IPAQ) was used to measure time spent on physical.......001). Less energy was used in leisure time among women living in a village (P<0.001). A similar tendency (non-significant) was found for men. Conclusion: IPAQ is a detailed method to measure physical activity in leisure time, home, work and transportation and provide information on both time and energy...

  18. Youth Physical Activity Resource Use and Activity Measured by Accelerometry

    Maslow, Andra L.; Colabianchi, Natalie

    2011-01-01

    Objectives: To examine whether use of physical activity resources (e.g., parks) was associated with daily physical activity measured by accelerometry. Methods: One hundred eleven adolescents completed a travel diary with concurrent accelerometry. The main exposure was self-reported use of a physical activity resource (none /1 resources). The main…

  19. The Evolution of the Physical Activity Field

    Blair, Steven N.; Powell, Kenneth E.

    2014-01-01

    This article includes an historical review of research on physical activity and health, and how the findings have contributed to physical activity participation and promotion today. In the 20th century, research began to accumulate on the effects of exercise on physiological functions, and later on the relation between regular activity and various…

  20. Biopsychosocial Benefits of Physical Activity in Children

    Ayse Meydanlioglu

    2015-06-01

    Full Text Available Physical activity levels in children have been steadily decreasing in recent years. Reduced physical activity leads to numerous chronic diseases at an early age, particularly obesity. Lifelong participation in physical activity and maintenance of ideal bodyweight are highly effective in the prevention of chronic diseases such as obesity, cardiovascular diseases, hypertension, Type II diabetes, lung and colon cancers. At the same time physical activity increases self-confidence, self-esteem and academic achievement, and reduces symptoms of depression. Therefore, this study was designed to improve awareness of professional groups and families working with children and adolescents about physical activity benefits on children health, as well as psychosocial benefits and planned to offer suggestions for increasing physical activity levels of children. [Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry 2015; 7(2: 125-135

  1. Nearby outdoor environments and seniors physical activities

    Zhe Wang

    2014-09-01

    Full Text Available More than 60% of older Americans have sedentary lifestyles1 1 According to DHHS (1996. and are recommended more physical activities for health benefit. Nearby outdoor environments on residential sites may impact older inhabitants׳ physical activities there (defined as walking, gardening, yard work, and other outdoor physical activities on residential sites. This study surveyed 110 assisted-living residents in Houston, Texas, regarding their previous residential sites before moving to a retirement community and physical activities there. Twelve environmental features were studied under four categories (typology, motivators, function, and safety. Based on data availability, a subset of 57 sample sites was analyzed in Geographic Information Systems. Hierarchical linear modeling was applied to estimate physical activities as a function of the environments. Higher levels of physical activity were found to be positively related with four environmental features (transitional-areas, connecting-paths, walk-ability, and less paving.

  2. Political activity for physical activity: health advocacy for active transport

    Amun Qa-t-a; Reeder Anthony I; Murdoch Linda; Richards Rosalina

    2011-01-01

    Abstract Effective health advocacy is a priority for efforts to increase population participation in physical activity. Local councils are an important audience for this advocacy. The aim of the current study was to describe features of advocacy for active transport via submissions to city council annual plans in New Zealand, and the impact of an information sheet to encourage the health sector to be involved in this process. Written submissions to city council's annual consultation process w...

  3. Physical Activity in Physical Education: Are Longer Lessons Better?

    Smith, Nicole J.; Monnat, Shannon M.; Lounsbery, Monica A. F.

    2015-01-01

    Background: The purpose of this study was to compare physical activity (PA) outcomes in a sample of high school (HS) physical education (PE) lessons from schools that adopted "traditional" versus "modified block" schedule formats. Methods: We used the System for Observing Fitness Instruction Time (SOFIT) to conduct observations…

  4. Break for Physical Activity: Incorporating Classroom-Based Physical Activity Breaks into Preschools

    Wadsworth, Danielle D.; Robinson, Leah E.; Beckham, Karen; Webster, Kip

    2012-01-01

    Engaging in moderate-to-vigorous physical activity is essential to lifelong health and wellness. Physical activity behaviors established in early childhood relate to physical activity behaviors in later years. However, research has shown that children are adopting more sedentary behaviors. Incorporating structured and planned physical activity…

  5. Comprehensive School Physical Activity Programs: Helping All Students Achieve 60 Minutes of Physical Activity Each Day

    Elliot, Eloise; Erwin, Heather; Hall, Tina; Heidorn, Brent

    2013-01-01

    The American Alliance for Health, Physical Education, Recreation and Dance recommends that all schools implement a comprehensive school physical activity program. Physical activity is important to the overall health and well-being of everyone, including all school age children. The benefits of physical activity are well documented and include the…

  6. Non-CpG Oligonucleotides Exert Adjuvant Effects by Enhancing Cognate B Cell-T Cell Interactions, Leading to B Cell Activation, Differentiation, and Isotype Switching

    Melinda Herbáth

    2015-01-01

    Full Text Available Natural and synthetic nucleic acids are known to exert immunomodulatory properties. Notably, nucleic acids are known to modulate immune function via several different pathways and various cell types, necessitating a complex interpretation of their effects. In this study we set out to compare the effects of a CpG motif containing oligodeoxynucleotide (ODN with those of a control and an inhibitory non-CpG ODN during cognate B cell-T cell interactions. We employed an antigen presentation system using splenocytes from TCR transgenic DO11.10 mice and the ovalbumin peptide recognized by the TCR as model antigen. We followed early activation events by measuring CD69 expression, late activation by MHC class II expression, cell division and antibody production of switched, and nonswitched isotypes. We found that both of the tested non-CpG ODN exerted significant immunomodulatory effects on early T cell and on late B cell activation events. Importantly, a synergism between non-CpG effects and T cell help acting on B cells was observed, resulting in enhanced IgG production following cognate T cell-B cell interactions. We propose that non-CpG ODN may perform as better adjuvants when a strong antigen-independent immune activation, elicited by CpG ODNs, is undesirable.

  7. Physical activity opportunities in afterschool programs

    Weaver, R. Glenn; Beets, Michael W.; Huberty, Jennifer; Freedman, Darcy; Turner-McGrievy, Gabrielle; Ward, Diane

    2015-01-01

    Afterschool programs (ASPs) have potential to provide children moderate-to-vigorous physical activity (MVPA). The availability and types (e.g., free play or organized activities) of physical activity opportunities, their structure (e.g., presence of lines, elimination games), and staff behaviors (e.g., encouragement, engaged) can influence children’s MVPA. This study explored these factors in 20 ASPs serving over 1,700 elementary-age children. The occurrence, types and structure of physical a...

  8. Nearby outdoor environments and seniors physical activities

    Zhe Wang

    2014-01-01

    More than 60% of older Americans have sedentary lifestyles1 1 According to DHHS (1996). and are recommended more physical activities for health benefit. Nearby outdoor environments on residential sites may impact older inhabitants׳ physical activities there (defined as walking, gardening, yard work, and other outdoor physical activities on residential sites). This study surveyed 110 assisted-living residents in Houston, Texas, regarding their previous residential sites before moving to a reti...

  9. Physical activities in elderly: benefits and barriers

    Francis, Purity

    2014-01-01

    Abstract: Aim: To research and create awareness on how physical activities have promoted health in the life of the elderly. Research Questions: 1. What are the benefits of physical Activity for Elderly? 2. What obstacles inhibit elderly from physical activities? Method: The study was a Literature review with deductive content analysis method used for analyzing articles. The search engines used was EBSCO, SAGE and Google Scholar. The results are grouped in categories and sub catego...

  10. Governor's nutrition and physical activity scorecard

    2012-01-01

    11 pages Research-based “best practices” that support proper nutrition and increased physical activity for K-12 students form the basis of a Web-based Governor’s Nutrition and Physical Activity Scorecard. Schools are encouraged to use the Web-based scorecard as a tool for identifying best practices and measuring progress towards meeting the nutrition and physical activity needs of students. The best practices and policies recommended by Virginia Action for Healthy Kids, national and state ...

  11. The Built Environment Predicts Observed Physical Activity

    Kelly, Cheryl; Wilson, Jeffrey S.; Schootman, Mario; Clennin, Morgan; Baker, Elizabeth A.; Miller, Douglas K.

    2014-01-01

    Background: In order to improve our understanding of the relationship between the built environment and physical activity, it is important to identify associations between specific geographic characteristics and physical activity behaviors. Purpose: Examine relationships between observed physical activity behavior and measures of the built environment collected on 291 street segments in Indianapolis and St. Louis. Methods: Street segments were selected using a stratified geographic samp...

  12. Measuring Physical Activity Environments: A Brief History

    Sallis, James F.

    2009-01-01

    Physical activity is usually done in specific types of places, referred to as physical activity environments. These often include parks, trails, fitness centers, schools, and streets. In recent years, scientific interest has increased notably in measuring physical activity environments. The present paper provides an historical overview of the contributions of the health, planning, and leisure studies fields to the development of contemporary measures. The emphasis is on attributes of the buil...

  13. Physical activity and breast cancer survival

    Ogunleye, Adeyemi A; Holmes, Michelle D.

    2009-01-01

    Physical activity improves quality of life after a breast cancer diagnosis, and a beneficial effect on survival would be particularly welcome. Four observational studies have now reported decreased total mortality among physically active women with breast cancer; the two largest have also reported decreased breast cancer specific mortality. The estrogen pathway and the insulin pathway are two potential mechanisms by which physical activity could affect breast cancer survival. Randomized trial...

  14. Physical Activity of Croatian Population: Cross-sectional Study Using International Physical Activity Questionnaire

    Jurakić, Danijel; Pedišić, Željko; Andrijašević, Mirna

    2009-01-01

    Aim To determine the physical activity level of the Croatian population in different domains of everyday life. Methods A random stratified sample of 1032 Croatians aged 15 years and older was interviewed using the official Croatian long version of the International Physical Activity Questionnaire (IPAQ). Total physical activity and physical activity in each of the 4 life domains – work, transport, domestic and garden, and leisure-time – were estimated. Physical activit...

  15. Social change and physical activity

    Engström, Lars-Magnus

    2008-01-01

    Today’s Western society is undergoing rapid change, and the speed of this process of change seems to be increasing. One of the major social changes is the gradual changeover from daily lives that contained high levels of physical effort to lives that are increasingly sedentary. A sedentary lifestyle is not without its problems. Several common illnesses are related to physical inactivity. Athletics, exercise, outdoor life and trend sports must be regarded as expressions of lifestyle and not as...

  16. Effect of Exercise Intensity on Differentiated and Undifferentiated Ratings of Perceived Exertion During Cycle and Treadmill Exercise in Recreationally Active and Trained Women

    Bolgar, Melinda R.; Carol E. Baker; Goss, Fredric L.; Elizabeth Nagle; Robert J. Robertson

    2010-01-01

    The purpose of the study is to examine the effect of aerobic exercise intensity on components of the differentiated perceived exertion model in young women performing weight bearing and non-weight bearing aerobic exercise. Subjects were 18-25 yr old women who were recreationally active (n = 19; VO2max = 33.40 ml·kg-1·min-1) and trained (N = 22; VO2max = 43.3 ml·kg-1·min-1). Subjects underwent two graded exercise tests (GXT) on a treadmill and bike which were separated by 48 hours. RPE-Overall...

  17. Determinants of Physical Activity in Active and Low-Active, Sixth Grade African-American Youth.

    Trost, Stewart G.; Pate, Russell R.; Ward, Dianne S.; Saunders, Ruth; Riner, William

    1999-01-01

    Compared determinants of physical activity in active and low-active African-American sixth graders, surveying students and making objective assessments of physical activity over seven days. Results indicated that physical activity self-efficacy, beliefs about physical activity outcomes, involvement in community-based physical activity, perception…

  18. Physical activity and physical fitness profiles of South African women

    Smit, Madelein; Strydom, Gert Lukas; Wilders, Cilas Jacobus

    2011-01-01

    The purpose of this study was to determine the leisure time physical activity (LTPA) participation and physical fitness (PF) levels of South African women of the various ethnic groups. Individuals between the ages of 30 and 60 years (=41.0; ±=4.6) who were part of a cross-sectional non-randomized availability population who voluntarily participated, were used in this study. The group that formed part of the physical activity survey included 3273 subjects (Asian =262; black=1357; coloured=239;...

  19. Active Learning Strategies in Physics Teaching

    Karamustafaoglu, Orhan

    2009-01-01

    The purpose of this study was to determine physics teachers' opinions about student-centered activities applicable in physics teaching and learning in context. A case study approach was used in this research. First, semi-structured interviews were carried out with 6 physics teachers. Then, a questionnaire was developed based on the data obtained…

  20. Political activity for physical activity: health advocacy for active transport

    Amun Qa-t-a

    2011-05-01

    Full Text Available Abstract Effective health advocacy is a priority for efforts to increase population participation in physical activity. Local councils are an important audience for this advocacy. The aim of the current study was to describe features of advocacy for active transport via submissions to city council annual plans in New Zealand, and the impact of an information sheet to encourage the health sector to be involved in this process. Written submissions to city council's annual consultation process were requested for 16 city councils over the period of three years (2007/08, 2008/09, and 2009/10. Submissions were reviewed and categories of responses were created. An advocacy information sheet encouraging health sector participation and summarising some of the evidence-base related to physical activity, active transport and health was released just prior to the 2009/10 submission time. Over the period of the study, city councils received 47,392 submissions, 17% of which were related to active transport. Most submissions came from city residents, with a small proportion (2% from the health sector. The largest category of submissions was in support of pedestrian and cycling infrastructure, design and maintenance of facilities and additional features to support use of these transport modes. Health arguments featured prominently in justifications for active transport initiatives, including concerns about injury risk, obesity, physical inactivity, personal safety and facilities for people with disabilities. There was evidence that the information sheet was utilised by some health sector submitters (12.5%, providing tentative support for initiatives of this nature. In conclusion, the study provides novel information about the current nature of health advocacy for active transport and informs future advocacy efforts about areas for emphasis, such as health benefits of active transport, and potential alliances with other sectors such as environmental

  1. Green Tea Catechin Metabolites Exert Immunoregulatory Effects on CD4(+) T Cell and Natural Killer Cell Activities.

    Kim, Yoon Hee; Won, Yeong-Seon; Yang, Xue; Kumazoe, Motofumi; Yamashita, Shuya; Hara, Aya; Takagaki, Akiko; Goto, Keiichi; Nanjo, Fumio; Tachibana, Hirofumi

    2016-05-11

    Tea catechins, such as (-)-epigallocatechin-3-O-gallate (EGCG), have been shown to effectively enhance immune activity and prevent cancer, although the underlying mechanism is unclear. Green tea catechins are instead converted to catechin metabolites in the intestine. Here, we show that these green tea catechin metabolites enhance CD4(+) T cell activity as well as natural killer (NK) cell activity. Our data suggest that the absence of a 4'-hydroxyl on this phenyl group (B ring) is important for the effect on immune activity. In particular, 5-(3',5'-dihydroxyphenyl)-γ-valerolactone (EGC-M5), a major metabolite of EGCG, not only increased the activity of CD4(+) T cells but also enhanced the cytotoxic activity of NK cells in vivo. These data suggest that EGC-M5 might show immunostimulatory activity. PMID:27112424

  2. Is Enhanced Physical Activity Possible Using Active Videogames?

    Baranowski, Tom; Baranowski, Janice; O'Connor, Teresia; Lu, Amy Shirong; Thompson, Debbe

    2012-01-01

    Our research indicated that 10–12-year-old children receiving two active Wii™ (Nintendo®; Nintendo of America, Inc., Redmond, WA) console videogames were no more physically active than children receiving two inactive videogames. Research is needed on how active videogames may increase physical activity.

  3. Adulthood lifetime physical activity and breast cancer.

    Peplonska, Beata; Lissowska, Jolanta; Hartman, Terryl J.; Szeszenia-Dabrowska, Neonila; Blair, Aaron; Zatonski, Witold; Sherman, Mark E.; Garcia-Closas, Montserrat; Brinton, Louise A.

    2008-01-01

    BACKGROUND: Epidemiologic studies have shown that breast cancer risk is reduced 30% to 40% in highly physically active compared with inactive women. However, the effects of moderate activities, timing of activities, and intervening effects of other risk factors remain less clear. METHODS: We analyzed data on physical activity patterns in 2176 incident breast cancer cases and 2326 controls in a population-based breast cancer case-control study in Poland conducted in 2000-2003. Using unconditio...

  4. Effectiveness of worksite physical activity counseling

    Proper, K.I.

    2003-01-01

    The aim of this thesis was to describe the effectiveness of a particular worksite physical activity intervention involving individual counseling of workers. First, a summary of the existing literature is given as to the effectiveness of worksite physical activity programs. A strong evidence was foun

  5. Interdisciplinary Best Practices for Adapted Physical Activity

    Szostak, Rick

    2016-01-01

    This article provides an introduction to the literature on interdisciplinary research. It then draws lessons from that literature for the field of adapted physical activity. It is argued that adapted physical activity should be a self-consciously interdisciplinary field. It should insist that research be performed according to recognized…

  6. Jumpin' Jaguars: Encouraging Physical Activity After School

    Erwin, Heather E.; Rose, Stephanie A.; Small, Sarah R.; Perman, Jay

    2016-01-01

    Many afterschool physical activity programs and curricula are available, but evaluation of their effectiveness is needed. Well-marketed programs such as the Child and Adolescent Trial for Cardiovascular Health (CATCH) Kids Club have shown limited effectiveness in increasing physical activity for participants in comparison to control groups.…

  7. Physical Activity before and after School

    Beighle, Aaron; Moore, Melanie

    2012-01-01

    This article discusses a variety of before- and after-school programs (BASPs) that can be implemented from preschool through 12th grade. These programs offer physical activity opportunities before and after school for youths of various ages, skill levels, and socioeconomic levels. In addition, strategies for the director of physical activity to…

  8. Staying Safe during Exercise and Physical Activity

    ... nih.gov/Go4Life Staying Safe during Exercise and Physical Activity There’s a way for almost every older adult ... have specific health conditions, discuss your exercise and physical activity plan with your health care provider. Endurance. Listen ...

  9. Evidence-based intervention in physical activity

    Heath, Gregory W; Parra, Diana C; Sarmiento, Olga L;

    2012-01-01

    Promotion of physical activity is a priority for health agencies. We searched for reviews of physical activity interventions, published between 2000 and 2011, and identified effective, promising, or emerging interventions from around the world. The informational approaches of community-wide and m...

  10. Physiological Response to Physical Activity in Children.

    Gilliam, Thomas B.

    This is a report on research in the field of physical responses of children to strenuous activity. The paper is divided into three subtopics: (1) peak performance measure in children; (2) training effects on children; and (3) importance of physical activity for children. Measurements used are oxygen consumption, ventilation, heart rate, cardiac…

  11. Promoting Physical Activity during Early Childhood

    Vidoni, Carla; Ignico, Arlene

    2011-01-01

    The prevalence of obesity in children and adolescents from low-income families in the USA has become a significant concern over the last 20 years. One of the major contributors to this problem is the lack of physical activity. The purpose of this paper is to describe initiatives designed to: (1) engage young children in physical activity during…

  12. Increasing Physical Activity through Recess. Research Brief

    Beighle, Aaron

    2012-01-01

    Regular physical activity promotes important health benefits, reduces risk for obesity and is linked with enhanced academic performance among students. The U.S. Surgeon General recommends that children engage in at least 60 minutes of moderate physical activity most days of the week, yet fewer than half of children ages 6 to 11 meet that…

  13. Intensity versus duration of physical activity

    Laursen, Adam Høgsbro; Kristiansen, Ole P; Marott, Jacob Louis;

    2012-01-01

    To explore the relative importance of leisure time physical activity (LTPA), walking and jogging on risk of developing the metabolic syndrome (MS).......To explore the relative importance of leisure time physical activity (LTPA), walking and jogging on risk of developing the metabolic syndrome (MS)....

  14. Activity Report of Reactor Physics Division - 1997

    The research and development activities of the Reactor Physics Division of the Indira Gandhi Centre for Atomic Research (IGCAR), Kalpakkam during 1997 are reported. The activities are arranged under the headings: nuclear data processing and validation, PFBR and KAMINI core physics, FBTR core physics, radioactivity and shielding and safety analysis. A list of publications of the Division and seminars delivered are included at the end of the report

  15. Physical Activity and Exercise in Dementia

    Sefa Lok

    2015-09-01

    Full Text Available Aging is a dynamic process that affects many systems in the body. Cognitive function with aging, including memory, intelligence, personality and behavior are affected at different levels. As time passes, durability of individuals and the amount of physical activity and exercise decrease. Apart from normal aging process, accompanying chronic brain syndrome of dementia will further reduce activities. Physical activity can provide opportunities for individuals with dementia in the path to socialize. Therefore, the role of physical activity and exercise in adapting an active lifestyle to protect the health of individuals with dementia is becoming increasingly important. Physical activity and exercise which would help in improvement of cognitive activity in dementia are briefly reviewed in this article. [Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry 2015; 7(3.000: 289-294

  16. Correlates of and physical activity counseling effect on attitude toward physical activity among older people

    Tsai, Li-Tang

    2011-01-01

    Among older adults, moderate regular physical activity, even if below the level to show fitness effect, leads to multiple health benefits. However, despite well-documented benefits of physical activity, the majority of adults in developed countries do not exercise. There is a need to investigate what influences attitude toward physical activity among older people to develop suitable health promotion scheme. The purpose of this study was to identify correlates of attitude toward physical activ...

  17. South African Generation Y students' motives for engaging in physical activity : physical activity and health

    Meyer, N; A.L. Bevan-Dye

    2014-01-01

    The purpose of this study was to determine Generation Y students' level of physical activity and the motivation for participating in physical activity. Despite there being a great deal of published literature that provides evidence of the benefits of engaging in physical activity and its influence on reducing certain dreaded illnesses, physical activity amongst the Generation Y cohort (individuals born between 1986 and 2005) is declining worldwide. In South Africa, the Generation Y cohort con...

  18. Neighborhood disadvantage, physical activity barriers, and physical activity among African American breast cancer survivors

    Antwan Jones; Paxton, Raheem J.

    2015-01-01

    In view of evidence that African American cancer survivors experience the greatest challenges in maintaining adequate levels of physical activity, this cross-sectional study was designed to determine whether individual and residential environment characteristics are associated with physical activity in this population. A total of 275 breast cancer survivors completed self-report items measuring sociodemographic variables, physical activity, and select barriers to physical activity in Spring o...

  19. Estimating Physical Activity Energy Expenditure with the Kinect Sensor in an Exergaming Environment

    David Nathan; Du Q Huynh; Jonas Rubenson; Michael Rosenberg

    2015-01-01

    Active video games that require physical exertion during game play have been shown to confer health benefits. Typically, energy expended during game play is measured using devices attached to players, such as accelerometers, or portable gas analyzers. Since 2010, active video gaming technology incorporates marker-less motion capture devices to simulate human movement into game play. Using the Kinect Sensor and Microsoft SDK this research aimed to estimate the mechanical work performed by the ...

  20. Active Learning in the Physics Classroom

    Naron, Carol

    Many students enter physics classes filled with misconceptions about physics concepts. Students tend to retain these misconceptions into their adult lives, even after physics instruction. Constructivist researchers have found that students gain understanding through their experiences. Researchers have also found that active learning practices increase conceptual understanding of introductory physics students. This project study sought to examine whether incorporating active learning practices in an advanced placement physics classroom increased conceptual understanding as measured by the force concept inventory (FCI). Physics students at the study site were given the FCI as both a pre- and posttest. Test data were analyzed using two different methods---a repeated-measures t test and the Hake gain method. The results of this research project showed that test score gains were statistically significant, as measured by the t test. The Hake gain results indicated a low (22.5%) gain for the class. The resulting project was a curriculum plan for teaching the mechanics portion of Advanced Placement (AP) physics B as well as several active learning classroom practices supported by the research. This project will allow AP physics teachers an opportunity to improve their curricular practices. Locally, the results of this project study showed that research participants gained understanding of physics concepts. Social change may occur as teachers implement active learning strategies, thus creating improved student understanding of physics concepts.

  1. Dietary and Physical Activity Behaviors of Middle School Youth: The Youth Physical Activity and Nutrition Survey

    Zapata, Lauren B.; Bryant, Carol A.; McDermott, Robert J.; Hefelfinger, Jennie A.

    2008-01-01

    Background: Obesity has become a national epidemic among youth. Declining physical activity and poor nutrition contribute to this epidemic. The purpose of this study was to obtain data on middle school students' physical activity and nutrition knowledge and practices. Methods: The Youth Physical Activity and Nutrition Survey was developed and…

  2. Changing Physician Practice of Physical Activity Counseling

    Eckstrom, Elizabeth; Hickam, David H.; Lessler, Daniel S; Buchner, David M.

    1999-01-01

    We conducted a prospective controlled trial to determine whether an educational intervention could improve resident physician self-efficacy and counseling behaviors for physical activity and increase their patients’ reported activity levels. Forty-eight internal medicine residents who practiced at a Department of Veterans Affairs hospital received either two workshops on physical activity counseling or no intervention. All residents completed questionnaires before and 3 months after the works...

  3. Activation of Neuropeptide Y Receptors Modulates Retinal Ganglion Cell Physiology and Exerts Neuroprotective Actions In Vitro

    Martins, João; Elvas, Filipe; Brudzewsky, Dan; Martins, Tânia; Kolomiets, Bogdan; Tralhão, Pedro; Gøtzsche, Casper R; Cavadas, Cláudia; Castelo-Branco, Miguel; Woldbye, David P D; Picaud, Serge; Santiago, Ana R; Ambrósio, António F

    2015-01-01

    Neuropeptide Y (NPY) is expressed in mammalian retina but the location and potential modulatory effects of NPY receptor activation remain largely unknown. Retinal ganglion cell (RGC) death is a hallmark of several retinal degenerative diseases, particularly glaucoma. Using purified RGCs and ex vivo...

  4. Chitosan Microparticles Exert Broad-Spectrum Antimicrobial Activity against Antibiotic-Resistant Micro-organisms without Increasing Resistance.

    Ma, Zhengxin; Kim, Donghyeon; Adesogan, Adegbola T; Ko, Sanghoon; Galvao, Klibs; Jeong, Kwangcheol Casey

    2016-05-01

    Antibiotic resistance is growing exponentially, increasing public health concerns for humans and animals. In the current study, we investigated the antimicrobial features of chitosan microparticles (CM), engineered from chitosan by ion gelation, seeking potential application for treating infectious disease caused by multidrug resistant microorganisms. CM showed excellent antimicrobial activity against a wide range of microorganisms, including clinically important antibiotic-resistant pathogens without raising resistant mutants in serial passage assays over a period of 15 days, which is a significantly long passage compared to tested antibiotics used in human and veterinary medicine. In addition, CM treatment did not cause cross-resistance, which is frequently observed with other antibiotics and triggers multidrug resistance. Furthermore, CM activity was examined in simulated gastrointestinal fluids that CM encounter when orally administered. Antimicrobial activity of CM was exceptionally strong to eliminate pathogens completely. CM at a concentration of 0.1 μg/mL killed E. coli O157:H7 (5 × 10(8) CFU/mL) completely in synthetic gastric fluid within 20 min. Risk assessment of CM, in an in vitro animal model, revealed that CM did not disrupt the digestibility, pH or total volatile fatty acid production, indicating that CM likely do not affect the functionality of the rumen. Given all the advantages, CM can serve as a great candidate to treat infectious disease, especially those caused by antibiotic-resistant pathogens without adverse side effects. PMID:27057922

  5. Leaf and branch extracts of Eriobotrya japonica exert antibacterial activity against ESBL-producing Escherichia coli and Klebsiella pneumoniae

    Elias Abdou

    2011-06-01

    Full Text Available In this study, the antimicrobial activity of leaves and branches of Eriobotrya japonica, a Lebanese endegenious plant, against Extended Spectrum Beta Lactamase -producing Escherichia coli and Klebsiella pneumoniae was determined  and the specific plant fraction responsible for this antimicrobial activity were identified. The plants were extracted with ethanol to yield the crude extract which was further subfractionated by different solvents to obtain the petroleum ether, the dichloromethane, the ethyl acetate and the aqueous fractions. The Minimum Inhibitory Concentrations (MIC and Minimum Bactericidal Concentrations (MBC were determined using broth microdilution. Both inhibitory and bactericidal effects of Eriobotrya japonica on Escherichia coli and Klebsiella pneumoniae were mainly observed with the crude extract of the plant, the ethyl acetate, the Dichloromethane, and the aqueous fractions. The antibacterial effect of the Petroleum ether fraction was limited with the leaf extract; however, it was acceptable with the branch extract. The lowest MIC90 was observed with ethyl acetate fraction for both leaf and branch extracts with Escherichia coli and Klebsiella pneumoniae. The concentrations at which most of strains were inhibited ranged between 40 μg/μl and 80 μg/μl. MICs and MBCs effects were detected within 1 dilution. This study constitutes a good example for the screening of antimicrobial activities of plants on highly resistant organisms of clinical importance; however, toxicity of these extracts needs more investigation. Key Words: Eriobotrya japonica, Extended Spectrum Beta Lacatamase, Minimum Inhibitory Concentration, medicinal herbs

  6. Aloe-emodin exerts a potent anticancer and immunomodulatory activity on BRAF-mutated human melanoma cells.

    Tabolacci, Claudio; Cordella, Martina; Turcano, Lorenzo; Rossi, Stefania; Lentini, Alessandro; Mariotti, Sabrina; Nisini, Roberto; Sette, Giovanni; Eramo, Adriana; Piredda, Lucia; De Maria, Ruggero; Facchiano, Francesco; Beninati, Simone

    2015-09-01

    Aim of this study was to extend the knowledge on the antineoplastic effect of aloe-emodin (AE), a natural hydroxyanthraquinone compound, both in metastatic human melanoma cell lines and in primary stem-like cells (melanospheres). Treatment with AE caused reduction of cell proliferation and induction of SK-MEL-28 and A375 cells differentiation, characterized by a marked increase of transamidating activity of transglutaminase whose expression remained unmodified. In vitro antimetastatic property of AE was evaluated by adhesion and Boyden chamber invasion assays. The effect of AE on melanoma cytokines/chemokines production was determined by a multiplex assay: interestingly AE showed an immunomodulatory activity through GM-CSF and IFN-γ production. We report also that AE significantly reduced the proliferation, stemness and invasive potential of melanospheres. Moreover, AE treatment significantly enhanced dabrafenib (a BRAF inhibitor) antiproliferative activity in BRAF mutant cell lines. Our results confirm that AE possesses remarkable antineoplastic properties against melanoma cells, indicating this anthraquinone as a promising agent for differentiation therapy of cancer, or as adjuvant in chemotherapy and targeted therapy. Further, its mechanisms of action support a potential efficacy of AE treatment to counteract resistance of BRAF-mutated melanoma cells to target therapy. PMID:26048310

  7. Organometallic iron(III-salophene exerts cytotoxic properties in neuroblastoma cells via MAPK activation and ROS generation.

    Kyu Kwang Kim

    Full Text Available The objective of the present study was to investigate the specific effects of Iron(III-salophene (Fe-SP on viability, morphology, proliferation, cell cycle progression, ROS generation and pro-apoptotic MAPK activation in neuroblastoma (NB cells. A NCI-DTP cancer screen revealed that Fe-SP displayed high toxicity against cell lines of different tumor origin but not tumor type-specificity. In a viability screen Fe-SP exhibited high cytotoxicity against all three NB cell lines tested. The compound caused cell cycle arrest in G1 phase, suppression of cells progressing through S phase, morphological changes, disruption of the mitochondrial membrane depolarization potential, induction of apoptotic markers as well as p38 and JNK MAPK activation, DNA degradation, and elevated generation of reactive oxygen species (ROS in SMS-KCNR NB cells. In contrast to Fe-SP, non-complexed salophene or Cu(II-SP did not raise ROS levels in NB or SKOV-3 ovarian cancer control cells. Cytotoxicity of Fe-SP and activation of caspase-3, -7, PARP, pro-apoptotic p38 and JNK MAPK could be prevented by co-treatment with antioxidants suggesting ROS generation is the primary mechanism of cytotoxic action. We report here that Fe-SP is a potent growth-suppressing and cytotoxic agent for in vitro NB cell lines and, due to its high tolerance in previous animal toxicity studies, a potential therapeutic drug to treat NB tumors in vivo.

  8. Environmental and Genetic Activation of Hypothalamic BDNF Modulates T-cell Immunity to Exert an Anticancer Phenotype.

    Xiao, Run; Bergin, Stephen M; Huang, Wei; Slater, Andrew M; Liu, Xianglan; Judd, Ryan T; Lin, En-Ju D; Widstrom, Kyle J; Scoville, Steven D; Yu, Jianhua; Caligiuri, Michael A; Cao, Lei

    2016-06-01

    Macroenvironmental factors, including a patient's physical and social environment, play a role in cancer risk and progression. Our previous studies show that living in an enriched environment (EE) providing complex stimuli confers an anticancer phenotype in mice mediated, in part by a specific neuroendocrine axis, with brain-derived neurotrophic factor (BDNF) as the key brain mediator. Here, we investigated how an EE modulated T-cell immunity and its role in the EE-induced anticancer effects. Our data demonstrated that CD8 T cells were required to mediate the anticancer effects of an EE in an orthotropic model of melanoma. In secondary lymphoid tissue (SLT), an EE induced early changes in the phenotype of T-cell populations, characterized by a decrease in the ratio of CD4 T helper to CD8 cytotoxic T lymphocytes (CTL). Overexpression of hypothalamic BDNF reproduced EE-induced T-cell phenotypes in SLT, whereas knockdown of hypothalamic BDNF inhibited EE-induced immune modulation in SLT. Both propranolol and mifepristone blocked the EE-associated modulation of CTLs in SLT, suggesting that both the sympathetic nervous system and the hypothalamic-pituitary-adrenal axis were involved. Our results demonstrated that enhanced anticancer effect of an EE was mediated at least in part through modulation of T-cell immunity and provided support to the emerging concept of manipulating a single gene in the brain to improve cancer immunotherapy. Cancer Immunol Res; 4(6); 488-97. ©2016 AACR. PMID:27045020

  9. Neuro-hormonal effects of physical activity in the elderly

    GiuseppeRengo

    2013-12-01

    Full Text Available Thanks to diagnostic and therapeutic advances, the elderly population is continuously increasing in the western countries. Accordingly, the prevalence of most chronic age-related diseases will increase considerably in the next decades, thus it will be necessary to implement effective preventive measures to face this epidemiological challenge. Among those, physical activity exerts a crucial role, since it has been proven to reduce the risk of cardiovascular diseases, diabetes, obesity, cognitive impairment and cancer. The favourable effects of exercise on cardiovascular homeostasis can be at least in part ascribed to the modulation of the neuro-hormonal systems implicated in cardiovascular pathophysiology. In the elderly, exercise has been shown to affect catecholamine secretion and biosynthesis, to positively modulate the renin-angiotensin-aldosterone system and to reduce the levels of plasma brain natriuretic peptides. Moreover, drugs modulating the neuro-hormonal systems may favourably affect physical capacity in the elderly. Thus, efforts should be made to actually make physical activity become part of the therapeutic tools in the elderly.

  10. Activity report of Reactor Physics Division- 1994

    This report contains the summaries of the various activities conducted during the year 1994 by the members of the Reactor Physics Division. These have been organised under the following topics: nuclear data processing and validation and uncertainty analysis; core physics and operation studies; reactor kinetics and safety analysis; radiation transport and shielding studies. A list of publications made by the members of the Division and the reactor physics seminars held during the year 1994 are included at the end of the report

  11. Noni (Morinda citrifolia L.) Fruit Extracts Improve Colon Microflora and Exert Anti-Inflammatory Activities in Caco-2 Cells.

    Huang, Hsin-Lun; Liu, Cheng-Tzu; Chou, Ming-Chih; Ko, Chien-Hui; Wang, Chin-Kun

    2015-06-01

    Intestinal microflora and inflammation are associated with the risk of inflammatory bowel diseases. Noni (Morinda citrifolia L.) has various bioactivities, but its effect on colon health remains unknown. This study focused on the effects of fermented noni fruit extracts on colon microflora and inflammation of colon epithelial cells. The anti-inflammatory activities of ethanol and ethyl acetate extracts on Caco-2 cells were evaluated including interleukin-8 (IL-8) and cyclooxygenase-2 (COX-2). The growth of Lactobacillus and Bifidobacterium species was promoted by ethanol extract. Ethyl acetate extract decreased intracellular reactive oxygen species and significantly suppressed COX-2, IL-8, and prostaglandin E2 production and neutrophil chemotaxis by suppressing the translocation of the p65 subunit. Quercetin was the main contributor to the anti-inflammatory activity. The fermented noni fruit promoted probiotic growths and downregulated the intracellular oxidation and inflammation in Caco-2 cells. These results suggest that fermented noni fruit might protect against inflammatory diseases of the colon. PMID:25651187

  12. HDAC inhibitor L-carnitine and proteasome inhibitor bortezomib synergistically exert anti-tumor activity in vitro and in vivo.

    Hongbiao Huang

    Full Text Available Combinations of proteasome inhibitors and histone deacetylases (HDAC inhibitors appear to be the most potent to produce synergistic cytotoxicity in preclinical trials. We have recently confirmed that L-carnitine (LC is an endogenous HDAC inhibitor. In the current study, the anti-tumor effect of LC plus proteasome inhibitor bortezomib (velcade, Vel was investigated both in cultured hepatoma cancer cells and in Balb/c mice bearing HepG2 tumor. Cell death and cell viability were assayed by flow cytometry and MTS, respectively. Gene, mRNA expression and protein levels were detected by gene microarray, quantitative real-time PCR and Western blot, respectively. The effect of Vel on the acetylation of histone H3 associated with the p21(cip1 gene promoter was examined by using ChIP assay and proteasome peptidase activity was detected by cell-based chymotrypsin-like (CT-like activity assay. Here we report that (i the combination of LC and Vel synergistically induces cytotoxicity in vitro; (ii the combination also synergistically inhibits tumor growth in vivo; (iii two major pathways are involved in the synergistical effects of the combinational treatment: increased p21(cip1 expression and histone acetylation in vitro and in vivo and enhanced Vel-induced proteasome inhibition by LC. The synergistic effect of LC and Vel in cancer therapy should have great potential in the future clinical trials.

  13. Physical Activity and Adolescent Female Psychological Development.

    Covey, Linda A.; Feltz, Deborah L.

    1991-01-01

    Relationships between self-reported past and present physical activity levels and self-image, sense of mastery, gender role identity, self-perceived physical ability, and self-perceived attractiveness were studied for 149 female high school sophomores, juniors, and seniors. Results are discussed in terms of adolescent emotional health. (SLD)

  14. Adherence to Exercise and Physical Activity: Preface.

    Morgan, William P.; Dishman, Rod K.

    2001-01-01

    Introduces a collection of papers on adherence to exercise programs and physical activity from the 2000 American Academy of Kinesiology and Physical Education conference, which included research on middle school boys and girls, college men and women, and men and women in the later years, as well as on the more traditional subject of middle aged…

  15. Annual report on nuclear physics activities

    This report surveys the activities in fundamental research from July 1, 1980 to June 30, 1981 at the three institutes of the KfK which are concerned with nuclear physics. The research program comprises laser spectroscopy, nuclear reactions with light ions and physics at medium and higher energies. (orig.)

  16. Physical activity and obesity in children

    Hills, Andrew P; Andersen, Lars Bo; Byrne, Nuala M

    2011-01-01

    Globally, obesity is affecting an increasing proportion of children. Physical activity plays an important role in the prevention of becoming overweight and obese in childhood and adolescence, and reducing the risk of obesity in adulthood. Puberty and the following adolescent period are acknowledged...... as particularly vulnerable times for the development of obesity due to sexual maturation and, in many individuals, a concomitant reduction in physical activity. In many Western settings, a large proportion of children and adolescents do not meet recommended physical activity guidelines and, typically, those who...... that children will live less healthy lives than their parents. Owing to the high risk of overweight adolescents becoming obese adults, the engagement of children and adolescents in physical activity and sport is a fundamental goal of obesity prevention....

  17. Physical Activity Improves Quality of Life

    ... Workplace Food and Beverage Toolkit Physical activity improves quality of life Updated:Mar 2,2015 Do you want to ... illnesses and diseases associated with aging and maintains quality of life and independence longer for seniors So why not ...

  18. Reactor physics activities in NEA member countries

    This document is a compilation of National activity reports presented at the thirty-third Meeting of the NEA Committee on Reactor Physics, held at OECD Headquarters, Paris, from 15th - 19th October 1990

  19. [Physical activity and bronchial asthma].

    Endre, László

    2016-06-26

    An article was published in the Lancet in 1935 about the therapy of asthmatic patients, using a special breathing exercise (the authors used a control group, too). Swimming, as a complementary therapy for asthmatic children, was first recommended in 1968, by authors from the United States. In Hungary, regular swimming training for asthmatic children is in use since August, 1981. As the result of this exercise, the physical fitness of asthmatic children (using this method regularly for years) increased dramatically, and it is much better compared to that found in the non asthmatic, non swimming children of the same age group. Their asthma medication requirement decreased, and the severity of their disease moderated considerably. On the other hand, asthma is not a rarity even among elite athletes. It is most frequent in the endurance sports (for example in Northern Europe among cross-country skiers its prevalence is between 14-54%, among long distance runners 15-24%, and among swimmers 13-44%). The possible reason is related to the fact that elite athletes inspirate 200 liter air per minutum (mostly through their mouth). The air pollution and the allergens can penetrate in their lower respiratory tract. The air causes cooling and drying of the mucosa of their airways and, as a consequence, mediators liberate which produce oedema of the mucosa, and bronchoconstriction. Beta-2-receptor agonists inhalation can prevent (or decrease significantly) this phenomenon. These agents are used regularly by elite athletes, too. The non-medical possibilities for prevention include wearing a special mask, frequent ventilation of the swimming pool's air, consumption of omega-3-fatty acid, and inhalation of dry salt (very small, and very clear sodiumchloride particles). PMID:27319382

  20. Activity report of Reactor Physics Division - 1993

    The research and development (R and D) activities of the Reactor Physics Division of Indira Gandhi Centre for Atomic Research (IGCAR), Kalpakkam during 1993 are reported. The activities are arranged under the headings: Nuclear Data Processing and validation, Core Physics and Operation Studies, Reactor Kinetics and Safety analysis, Reactor Noise Analysis and Radiation Transport and Shielding Studies. List of publication is given at the end. (author). refs., figs., tabs

  1. Psychological benefits of exercise and physical activity

    Biddle, Stuart J. H.

    1993-01-01

    This paper reviews contemporary literatura on the psychological benefits of regular involvement in physical activity and exercise. Despite methodological problems, the evidence points towards favourable effects for physical activity for reducing anxiety, depression and reactivity to stress, as well as enhancing aspects of self-esteem. However, the mechanisms underpinning such effects are still unresolved and future research is required on the motivational effects of affective changes from exe...

  2. Activity report of Reactor Physics Division-1995

    The research and development (R and D) activities of the Reactor Physics Division of Indira Gandhi Centre for Atomic Research (IGCAR), Kalpakkam during 1995 are reported. The activity are arranged under the headings: Nuclear Data Processing and Validation, Core Physics and Operation Studies, Reactor Kinetics and Safety analysis, Reactor Noise Analysis and Radiation Transport and Shielding Studies. List of publication is given at the end. refs., figs., tabs

  3. Physical activity, fitness, and gray matter volume

    Erickson, Kirk I.; Leckie, Regina L; Weinstein, Andrea M.

    2014-01-01

    In this review we explore the association between physical activity, cardiorespiratory fitness, and exercise on gray matter volume in older adults. We conclude that higher cardiorespiratory fitness levels are routinely associated with greater gray matter volume in the prefrontal cortex and hippocampus, and less consistently in other regions. We also conclude that physical activity is associated with greater gray matter volume in the same regions that are associated with cardiorespiratory fitn...

  4. Diabetes, physical activity and endometrial cancer

    Friberg, Emilie

    2006-01-01

    Accumulating evidence suggests that hyperinsulinemia, in the context of insulin resistance, is associated with carcinogenesis. Physical activity is involved in the regulation of metabolic and hormonal pathways and is an important factor affecting hyperinsulinemia, insulin resistance and body weight. The major modifiable determinants of insulin resistance, hyperinsulinemia, and diabetes such as obesity, and physical activity, have also been shown to be risk factors for endome...

  5. Physical activity, muscle function, falls and fractures

    Karlsson, Magnus K; Nordqvist, Anders; Karlsson, Caroline

    2008-01-01

    Study design: A thematic review. Objectives: To evaluate if physical activity enhances muscle strength, improves balance, and reduces the fall frequency and the fracture incidence. Background: One of the major medical problems of today is the increasing incidence of fragility fractures. Muscle strength and fall is one of the major determinants of a fracture. If physical activity could increase muscle strength, improve balance and reduce the fall frequency, then training could be recommended a...

  6. Physical activity in obesity and metabolic syndrome

    Strasser, Barbara

    2012-01-01

    Biological aging is typically associated with a progressive increase in body fat mass and a loss of lean body mass. Owing to the metabolic consequences of reduced muscle mass, it is understood that normal aging and/or decreased physical activity may lead to a higher prevalence of metabolic disorders. Lifestyle modification, specifically changes in diet, physical activity, and exercise, is considered the cornerstone of obesity management. However, for most overweight people it is difficult to ...

  7. Water extract from Pleurotus pulmonarius with antioxidant activity exerts in vivo chemoprophylaxis and chemosensitization for liver cancer.

    Xu, Wen Wen; Li, Bin; Lai, Emily Tsz Ching; Chen, Lei; Huang, Jim Jun Hui; Cheung, Annie Lai Man; Cheung, Peter Chi Keung

    2014-01-01

    Chemoprophylaxis and chemosensitization are promising strategies to combat human cancers. Natural antioxidant agents show great promise in cancer therapy, and the use of edible mushrooms against cancer is receiving more interest globally. In this study, the radical scavenging activities including diphenyl-1-picrylhydrazyl, superoxide anion radical, hydroxyl radical, and hydrogen peroxide were compared among hot water extracts from 3 edible mushrooms, among which Pleurotus pulmonarius (Pp) possessed the highest antioxidant potential. Oral administration of Pp 2 wk in advance could markedly inhibit the incidence and size of tumor (Huh7 liver cancer cells) with an inhibition rate of 93.1% in nude mice. No obvious side effect was observed in the Pp-treated mice as indicated by their body weight and histological analysis of major organs. The cancer prevention by Pp treatment might be explained by the inhibition of cancer cell proliferation indicated by reduction of ki-67 staining and the inactivation of phosphoinositide 3-kinase (PI3K)/AKT signaling pathway in the Pp-treated mice. Furthermore, a significant synergistic effect was observed when the mice were treated with a combination of low dose of cisplatin and Pp. Taken together, these results suggest the potential application of Pp as an adjuvant in the chemotherapy of liver cancer. PMID:25072857

  8. Icariin exerts estrogen-like activity in ameliorating EAE via mediating estrogen receptor β, modulating HPA function and glucocorticoid receptor expression

    Wei, Zhisheng; Wang, Mengxia; Hong, Mingfan; Diao, Shengpeng; Liu, Aiqun; Huang, Yeqing; Yu, Qingyun; Peng, Zhongxing

    2016-01-01

    Background: Estrogen exerts neuroprotective and anti-inflammatory effects in EAE and multiple sclerosis (MS), but its clinical application is hindered due to side effects and risk of tumor. Phytoestrogen structurally or functionally mimics estrogen with fewer side effects than endogenous estrogen. Icariin (ICA), an active component of Epimedium extracts, demonstrates estrogen-like neuroprotective effects. However, it is unclear whether ICA is effective in EAE and what are the underlying mechanisms. Objective: To determine the therapeutic effects of ICA in EAE and explore the possible mechanisms. Methods: C57BL/6 EAE mice were treated with Diethylstilbestrol, different dose of ICA and mid-dose ICA combined with ICI 182780. The clinical scores and serum Interleukin-17 (IL-17), Corticosterone (CORT) concentrations were then analyzed. Western blot were performed to investigate the expressions of glucocorticoid receptor (GR), estrogen receptor alpha (ERα) and ERβ in the cerebral white matter of EAE mice. Results: High dose ICA is equally effective in ameliorating neurological signs of EAE as estrogen. Estrogen and ICA has no effects on serum concentrations of IL-17 in EAE. While the CORT levels were decreased by ICA at mid or high doses, the expressions of GR, ERα and ERβ were up-regulated by estrogen or different doses of ICA in a dosedependent manner. Estrogen induced the elevation of ERα more markedly than ICA. In contrast, ICA at mid and high doses promoted ERβ more significantly than estrogen. Conclusion: ICA exerts estrogen-like activity in ameliorating EAE via mediating ERβ, modulating HPA function and up-regulating the expression of GR in cerebral white matter. ICA may be a promising therapeutic option for MS.

  9. Student Active Learning Methods in Physical Chemistry

    Hinde, Robert J.; Kovac, Jeffrey

    2001-01-01

    We describe two strategies for implementing active learning in physical chemistry. One involves supplementing a traditional lecture course with heavily computer-based active-learning exercises carried out by cooperative groups in a department computer lab. The other uses cooperative learning almost exclusively, supplemented by occasional mini-lectures. Both approaches seemed to result in better student learning and a more positive attitude toward the subject. On the basis of our respective experiences using active learning techniques, we discuss some of the strengths of these techniques and some of the challenges we encountered using the active-learning approach in teaching physical chemistry.

  10. Physical Activity Design Guidelines for School Architecture.

    Jeri Brittin

    Full Text Available Increasing children's physical activity at school is a national focus in the U.S. to address childhood obesity. While research has demonstrated associations between aspects of school environments and students' physical activity, the literature currently lacks a synthesis of evidence to serve as a practical, spatially-organized resource for school designers and decision-makers, as well as to point to pertinent research opportunities. This paper describes the development of a new practical tool: Physical Activity Design Guidelines for School Architecture. Its aims are to provide architects and designers, as well as school planners, educators, and public health professionals, with strategies for making K-12 school environments conducive to healthy physical activity, and to engage scientists in transdisciplinary perspectives toward improved knowledge of the school environment's impact. We used a qualitative review process to develop evidence-based and theory-driven school design guidelines that promote increased physical activity among students. The design guidelines include specific strategies in 10 school design domains. Implementation of the guidelines is expected to enable students to adopt healthier physical activity behaviors. The tool bridges a translational gap between research and environmental design practice, and may contribute to setting new industry and education standards.

  11. Physical active rest in education of active personality of students

    Zaycev V.P.; Manucharyan S.V.; Kramskoy S.I.

    2010-01-01

    Meaningfulness of physical recreation is rotined in education of active personality of students. Research material is literary sources on this issue. Factors which influence on an educate function of personality of students are considered. Application of physical recreation is grounded for education of active personality of students. It is marked that physical recreation in pedagogical process decides educate, educational, health and social tasks. It positively influences on education of acti...

  12. Sport Fields as Potential Catalysts for Physical Activity in the Neighbourhood

    John C. Spence

    2012-01-01

    Full Text Available Physical activity is associated with access to recreational facilities such as sports fields. Because it is not clear whether objectively- or subjectively-assessed access to facilities exerts a stronger influence on physical activity, we investigated the association between the objective and perceived accessibility of sport fields and the levels of self-reported physical activity among adults in Edmonton, Canada. A sample of 2879 respondents was surveyed regarding their socio-demographics, health status, self-efficacy, levels of physical activity, as well as their perceptions of built environment in relation to physical activity. Neighbourhood-level data were obtained for each respondent based on their residence. Accessibility to facilities was assessed using the enhanced Two-Step Floating Catchment Area method. Geographic Information Systems were employed. A logistic regression was performed to predict physical activity using individual- and neighbourhood-level variables. Women, older individuals, and individuals with higher educational attainment were less likely to be physically active. Also, individuals with higher self-efficacy and higher objectively-assessed access to facilities were more likely to be physically active. Interventions that integrate provision of relevant programs for various population groups and of improved recreational facilities may contribute to sport fields becoming catalysts for physical activity by generating movement both on the site and in the neighbourhood.

  13. Recombinant hamster oviductin is biologically active and exerts positive effects on sperm functions and sperm-oocyte binding.

    Xiaojing Yang

    Full Text Available Studies carried out in several mammalian species suggest that oviductin, also known as oviduct-specific glycoprotein or OVGP1, plays a key role in sperm capacitation, fertilization, and development of early embryos. In the present study, we used recombinant DNA technology to produce, for the first time, recombinant hamster OVGP1 (rHamOVGP1 in human embryonic kidney 293 (HEK293 cells. rHamOVGP1 secreted in the culture medium was purified by affinity chromatography. The resulting protein migrated as a poly-dispersed band of 160-350 kDa on SDS-PAGE corresponding to the molecular mass of the native HamOVGP1. Subsequent mass spectrometric analysis of the purified rHamOVGP1 confirmed its identity as HamOVGP1. Immunocytochemistry demonstrated binding of rHamOVGP1 to the mid-piece and head of hamster sperm and to the zona pellucida (ZP of ovarian oocytes. In vitro functional experiments showed that addition of rHamOVGP1 in the capacitation medium further enhanced tyrosine phosphorylation of two sperm proteins of approximately 75 kDa and 83 kDa in a time-dependent manner. After 3 hours of incubation in the presence of rHamOVGP1, a significant increase in acrosome reaction was measured. Pretreatment of either sperm or oocyte with 20 μg/ml of rHamOVGP1 prior to sperm-egg binding assay significantly increased the number of sperm bound to the ZP. Addition of rHamOVGP1 in the medium during sperm-egg binding with either oocyte or sperm pretreated with rHamOVGP1 also saw an increase in the number of sperm bound to ZP. In all experimental conditions, the effect of rHamOVGP1 on sperm-oocyte binding was negated by the addition of monoclonal anti-HamOVGP1 antibody. The successful production and purification of a biologically active rHamOVGP1 will allow further exploration of the function of this glycoprotein in reproductive function.

  14. Evaluation of physical activity of disabled people by modified International Physical Activity Questionnaire (IPAQ.

    Boguszewski Dariusz.

    2012-12-01

    Full Text Available Introduction. The aim of the study was an adaptation the International Physical Activity Questionnaire for disabled people moving on wheelchairs, and check and objectification of the proposed tool. Material and methods. The research covered 69 disabled people (8 women and 61 men. All group was divided into two subgroups: regularly practicing sportsmen - Group 1 and people who were not practicing any sport - Group 2. Research tool was International Physical Activity Questionnaire (short version adapted for disabled people. Results. Averaged results of physical activity, expressed in MET, showed the differences between groups (Groups 1 average 7418 MET, Group 2 average 2158 MET, p=0.000. The biggest differences (p=0.000 were spotted in intensive physical activity. People regularly practicing sport training also devoting more time on activities related to locomotion. 31 of sportsmen characterized high level of physical activity and 6 - medium. In the second group 9 people were in high level, 11 in medium and 14 in low level of physical activity. Conclusions. 1. Almost half of people who were not practicing any sport was characterized by an insufficient level of physical activity. It means that the persons who not taking sports activities are also less active while performing daily chores and leisure. 2. The modified International Physical Activity Questionnaire (IPAQ can be an effective tool for the evaluation of physical activity of disabled people moving on wheelchairs.

  15. Physical activity, obesity and cardiovascular diseases.

    Lakka, T A; Bouchard, C

    2005-01-01

    Sedentary lifestyle and overweight are major public health, clinical, and economical problems in modern societies. The worldwide epidemic of excess weight is due to imbalance between physical activity and dietary energy intake. Sedentary lifestyle, unhealthy diet, and consequent overweight and obesity markedly increase the risk of cardiovascular diseases. Regular physical activity 45-60 min per day prevents unhealthy weight gain and obesity, whereas sedentary behaviors such as watching television promote them. Regular exercise can markedly reduce body weight and fat mass without dietary caloric restriction in overweight individuals. An increase in total energy expenditure appears to be the most important determinant of successful exercise-induced weight loss. The best long-term results may be achieved when physical activity produces an energy expenditure of at least 2,500 kcal/week. Yet, the optimal approach in weight reduction programs appears to be a combination of regular physical activity and caloric restriction. A minimum of 60 min, but most likely 80-90 min of moderate-intensity physical activity per day may be needed to avoid or limit weight regain in formerly overweight or obese individuals. Regular moderate intensity physical activity, a healthy diet, and avoiding unhealthy weight gain are effective and safe ways to prevent and treat cardiovascular diseases and to reduce premature mortality in all population groups. Although the efforts to promote cardiovascular health concern the whole population, particular attention should be paid to individuals who are physically inactive, have unhealthy diets or are prone to weight gain. They have the highest risk for worsening of the cardiovascular risk factor profile and for cardiovascular disease. To combat the epidemic of overweight and to improve cardiovascular health at a population level, it is important to develop strategies to increase habitual physical activity and to prevent overweight and obesity in

  16. Resposta da pressão arterial ao esforço em adolescentes: influência do sobrepeso e obesidade Blood pressure response to physical exertion in adolescents: influence of overweight and obesity

    Luciana Carletti

    2008-07-01

    Full Text Available FUNDAMENTO: A resposta aguda da pressão arterial ao esforço tem sido utilizada como indicador de risco para o desenvolvimento de hipertensão arterial. Os fatores associados com essa resposta precisam ser esclarecidos a fim de se intervir na prevenção da doença hipertensiva. OBJETIVO: Descrever o comportamento das variáveis cardiovasculares ao esforço agudo em adolescentes com excesso de peso, por meio de teste cardiopulmonar. MÉTODOS: A amostra foi constituída de 104 adolescentes (56 meninos e 48 meninas, divididos nos grupos de sobrepeso/obesos (GSO e eutróficos (GE. Foram aferidas variáveis antropométricas (peso, estatura e IMC, de composição corporal (dobra cutânea e variáveis hemodinâmicas de pressão arterial sistólica (PAS e diastólica (PAD e freqüência cardíaca (FC, no repouso e no esforço máximo do teste cardiopulmonar. RESULTADOS: No grupo masculino, identificaram-se maiores valores de pressão arterial sistólica de repouso para o GSO, quando comparados com o GE (113 ± 13 vs 106 ± 8 mmHg; p = 0,009, a PAS pré-exercício (120 ± 14 vs 109 ± 10 mmHg; p = 0,003 e de PAS na carga máxima de trabalho (156 ± 20 vs 146 ± 14 mmHg; p = 0,03. No grupo feminino, apenas a PAS pré-exercício foi superior no grupo de sobrepeso, quando isso foi comparado com as eutróficas (114 ± 11 vs 106 ± 10 mmHg; p = 0,009. CONCLUSÃO: A resposta pressórica durante o exercício foi mais exacerbada em adolescentes obesos quando comparada com àquela obtida em eutróficos, o que indica maior reatividade ao estresse físico.BACKGROUND: The acute blood pressure response to physical exertion has been used as an indicator of the risk of developing hypertension. The factors associated with this response need to be clarified for timely intervention in preventing hypertensive disease. OBJECTIVE: To describe the response of cardiovascular variables to acute physical exertion in overweight adolescents using cardiopulmonary exercise testing

  17. International Centre for Theoretical Physics. Scientific Activities in 1983

    The main activities and results of the ICTP during 1983 are reported, according to the following programme components: Physics and energy (Plasma physics; Non-conventional energy; Nuclear physics); Fundamental physics (Elementary particles and fundamental theory); Physics of the living state (Medical physics; Applications of physics to medicine and biology); Physics and technology (Condensed matter physics and related; Atomic, molecular and laser physics; Physics of communications); Mathematics (Applicable mathematics); Physics of the environment and of natural resources (Soil physics; Geophysics); other fields

  18. Promoting Physical Activity among Underserved Populations.

    Mendoza-Vasconez, Andrea S; Linke, Sarah; Muñoz, Mario; Pekmezi, Dori; Ainsworth, Cole; Cano, Mayra; Williams, Victoria; Marcus, Bess H; Larsen, Britta A

    2016-01-01

    Underserved populations, including racial/ethnic minorities, individuals with low socioeconomic status, and individuals with physical disabilities, are less likely to engage in sufficient moderate to vigorous physical activity (MVPA) and are thus at increased risk of morbidity and mortality. These populations face unique challenges to engaging in MVPA. Learning how to overcome these challenges is a necessary first step in achieving health equity through health promotion research. In this review of the literature, we discuss issues and strategies that have been used to promote MVPA among individuals from underserved populations, focusing on recruitment, intervention delivery, and the use of technology in interventions. Physical activity promotion research among these vulnerable populations is scarce. Nevertheless, there is preliminary evidence of efficacy in the use of certain recruitment and intervention strategies including tailoring, cultural adaptation, incorporation of new technologies, and multilevel and community-based approaches for physical activity promotion among different underserved populations. PMID:27399827

  19. Physical activity and cortisol in anorexia nervosa.

    Klein, Diane Alix; Mayer, Laurel E S; Schebendach, Janet Ellen; Walsh, B Timothy

    2007-06-01

    Elevated physical activity is commonly observed among patients with Anorexia Nervosa (AN) and can manifest in several forms. While elevated physical activity may play a key role in the pathophysiology of this disorder, much remains unknown about it, including the relationship among its various manifestations, and their underlying mechanism(s). The purposes of the current study were to (1) quantify locomotor activity in inpatients with AN using an accelerometer, (2) determine the association between locomotor activity and exercise history and (3) determine the association between urinary cortisol and physical activity. Thirty-six women hospitalized with AN wore activity armbands for 48 h during the first 2 weeks of hospitalization, collected 24-h urine to measure cortisol, and completed rating forms. Activity counts varied more than four-fold among individuals but were consistent within individuals over the 2 monitoring days (pactivity counts were positively correlated with pre-hospitalization attitude towards exercise as measured by the Commitment to Exercise Scale (CES; p=0.032). Forty-two percent of women reported "high" exercise in the 3 months before hospitalization; compared to non-high-exercising patients, these women demonstrated a higher CES score (pactivity counts (p=0.059). Urinary cortisol was positively associated with activity counts (p=0.044) and CES score (p=0.018). These data suggest that some women with AN have a higher "drive" for physical activity that persists into early hospitalization. HPA axis abnormalities may be associated with this state. PMID:17462830

  20. Physical activity and modernization among Bolivian Amerindians.

    Michael Gurven

    Full Text Available BACKGROUND: Physical inactivity is a growing public health problem, and the fourth leading risk factor for global mortality. Conversely, indigenous populations living traditional lifestyles reportedly engage in vigorous daily activity that is protective against non-communicable diseases. Here we analyze physical activity patterns among the Tsimane, forager-horticulturalists of Amazonian Bolivia with minimal heart disease and diabetes. We assess age patterns of adult activity among men and women, test whether modernization affects activity levels, and examine whether nascent obesity is associated with reduced activity. METHODS AND FINDINGS: A factorial method based on a large sample of behavioral observations was employed to estimate effects of age, sex, body mass index, and modernization variables on physical activity ratio (PAR, the ratio of total energy expenditure to basal metabolic rate. Accelerometry combined with heart rate monitoring was compared to the factorial method and used for nighttime sampling. Tsimane men and women display 24 hr physical activity level (PAL of 2.02-2.15 and 1.73-1.85, respectively. Little time was spent "sedentary", whereas most activity was light to moderate, rather than vigorous. Activity peaks by the late twenties in men, and declines thereafter, but remains constant among women after the early teens. Neither BMI, fat free mass or body fat percentage are associated with PAR. There was no negative effect of modernization on physical activity. CONCLUSIONS: Tsimane display relatively high PALs typical of other subsistence populations, but of moderate intensity, and not outside the range of developed populations. Despite rapidly increasing socioeconomic change, there is little evidence that total activity has yet been affected. Overweight and obesity are more prevalent among women than men, and Spanish fluency is associated with greater obesity in women. The lack of cardiovascular disease among Tsimane is unlikely

  1. Evaluating Active U: an internet-mediated physical activity program

    Goodrich David E

    2009-09-01

    Full Text Available Abstract Background Engaging in regular physical activity can be challenging, particularly during the winter months. To promote physical activity at the University of Michigan during the winter months, an eight-week Internet-mediated program (Active U was developed providing participants with an online physical activity log, goal setting, motivational emails, and optional team participation and competition. Methods This study is a program evaluation of Active U. Approximately 47,000 faculty, staff, and graduate students were invited to participate in the online Active U intervention in the winter of 2007. Participants were assigned a physical activity goal and were asked to record each physical activity episode into the activity log for eight weeks. Statistics for program reach, effectiveness, adoption, and implementation were calculated using the Re-Aim framework. Multilevel regression analyses were used to assess the decline in rates of data entry and goal attainment during the program, to assess the likelihood of joining a team by demographic characteristics, to test the association between various predictors and the number of weeks an individual met his or her goal, and to analyze server load. Results Overall, 7,483 individuals registered with the Active U website (≈16% of eligible, and 79% participated in the program by logging valid data at least once. Staff members, older participants, and those with a BMI P Conclusion Internet-mediated physical activity interventions that focus on physical activity logging and goal setting while incorporating team competition may help a significant percentage of the target population maintain their physical activity during the winter months.

  2. Reliability and validity of the transport and physical activity questionnaire (TPAQ for assessing physical activity behaviour.

    Emma J Adams

    Full Text Available BACKGROUND: No current validated survey instrument allows a comprehensive assessment of both physical activity and travel behaviours for use in interdisciplinary research on walking and cycling. This study reports on the test-retest reliability and validity of physical activity measures in the transport and physical activity questionnaire (TPAQ. METHODS: The TPAQ assesses time spent in different domains of physical activity and using different modes of transport for five journey purposes. Test-retest reliability of eight physical activity summary variables was assessed using intra-class correlation coefficients (ICC and Kappa scores for continuous and categorical variables respectively. In a separate study, the validity of three survey-reported physical activity summary variables was assessed by computing Spearman correlation coefficients using accelerometer-derived reference measures. The Bland-Altman technique was used to determine the absolute validity of survey-reported time spent in moderate-to-vigorous physical activity (MVPA. RESULTS: In the reliability study, ICC for time spent in different domains of physical activity ranged from fair to substantial for walking for transport (ICC = 0.59, cycling for transport (ICC = 0.61, walking for recreation (ICC = 0.48, cycling for recreation (ICC = 0.35, moderate leisure-time physical activity (ICC = 0.47, vigorous leisure-time physical activity (ICC = 0.63, and total physical activity (ICC = 0.56. The proportion of participants estimated to meet physical activity guidelines showed acceptable reliability (k = 0.60. In the validity study, comparison of survey-reported and accelerometer-derived time spent in physical activity showed strong agreement for vigorous physical activity (r = 0.72, p<0.001, fair but non-significant agreement for moderate physical activity (r = 0.24, p = 0.09 and fair agreement for MVPA (r = 0.27, p = 0.05. Bland

  3. Health, fitness, physical activity, and morbidity of middle aged male factory workers. I.

    Tuxworth, W.; Nevill, A M; White, C.; Jenkins, C

    1986-01-01

    A description of the fitness, physical activity of lifestyle, and some aspects of health status and attitudes in a population of male factory workers aged 35-60 is presented as the first part of a report on a study of morbidity in this population. A total of 1394 subjects were included, undergoing medical examination, fitness testing by bicycle ergometry, assessment of body fat, and interview questionnaire. The inter-relation of fitness, body composition, habitual exertion, health risk factor...

  4. Physical Activity Index among Malaysian Youth

    Norlena Salamudin

    2013-08-01

    Full Text Available Over the last several years, physical inactivity has increasingly been recognized as a major health risk among Malaysians. The Government of Malaysia under the Ministry of Youth has adopted many programs aiming at keeping the nation healthy. Among such programs are Malaysia Cergas and RakanSukan. Trends in the physical activity levels and participation patterns of Malaysians has never been researched or monitored. Thus, there is no available evidence to serve as a foundation for decision making regarding this matter. This research was conducted with the aim of providing a unique insight into the physical activity patterns and fitness levels of Malaysian youths, as well as providing a detailed baseline data that can be use for developing policy and planning physical activity strategies for the youths. This article provides insights into the current physical activity levels among Malaysian youths in the Klang Valley and the prognosis for change; the individual and collective benefits of a more active Malaysia; and, the type of strategies needed to help Malaysians especially the youths, become and remain active.

  5. Identifying physical activity gender differences among youth

    Physical activity (PA) is an important part of a healthy lifestyle and reduces risk of certain chronic diseases. Many youth do not currently meet PA guidelines; evidence suggests that girls are less active than boys are at all ages. PA differences need to be understood, so that gender-specific inter...

  6. Healthy active living: Physical activity guidelines for children and adolescents

    Lipnowski, Stan; LeBlanc, Claire MA

    2012-01-01

    The epidemic of childhood obesity is rising globally. Although the risk factors for obesity are multifactorial, many are related to lifestyle and may be amenable to intervention. These factors include sedentary time and non-exercise activity thermogenesis, as well as the frequency, intensity, amounts and types of physical activity. Front-line health care practitioners are ideally suited to monitor children, adolescents and their families’ physical activity levels, to evaluate lifestyle choice...

  7. Platelet-activating factor and hydrogen peroxide exert a dual modulatory effect on the transcription of LXRα and its target genes in human neutrophils.

    Reyes-Quiroz, María E; Alba, Gonzalo; Sáenz, Javier; Geniz, Isabel; Jiménez, Juan; Martín-Nieto, José; Santa-María, Consuelo; Sobrino, Francisco

    2016-09-01

    Liver X receptors (LXRs) are ligand-activated nuclear receptors involved mainly in the regulation of cholesterol metabolism in many organs, including liver and intestine, as well as in macrophages and neutrophils. Besides, both anti-inflammatory and pro-inflammatory properties have been ascribed to LXRs. The effect of the inflammatory condition on the expression of LXRα and its target genes has not been previously addressed in human neutrophils. We have described that platelet-activating factor (PAF) and hydrogen peroxide (H2O2) are potent pro-inflammatory mediators that link the haemostatic and innate immune systems. In this work we report that H2O2 at low doses (1 pM-1μM) exerts an inhibitory effect on TO901317-induced mRNA expression of LXRα and of its target genes encoding the ATP-binding cassette (ABC) transporters ABCA1 and ABCG1, and the sterol regulatory element-binding protein 1c (SREBP1c). However, an opposite behaviour, i.e., a transcription-enhancing effect, was found at higher H2O2 doses (100-500μM) on most of these genes. A similar dual effect was observed when the pro-inflammatory molecule PAF was used. Interestingly, H2O2 production separately elicited by 10nM PAF or 1μM H2O2 was similarly low, and analogously, H2O2 production levels elicited by 5μM PAF or 100μM H2O2 were similarly high when they were compared. On the other hand, low doses of PAF or H2O2 induced phosphorylation of extracellular signal-regulated kinases 1 and 2 (ERK 1/2) and NF-κB activation, However, PAF or H2O2 at high doses did not produce changes in NF-κB activation levels. In summary, our results show that H2O2, either exogenous or PAF-induced, exerts a dual regulation on mRNA expression of LXRα and its target genes. PMID:27351826

  8. Perceived risk of osteoporosis: Restricted physical activities?

    Reventlow, Susanne

    2007-01-01

    Objective. To explore elderly women's physical activity in relation to their perception of the risk of osteoporosis. Design. Qualitative study using in-depth interviews. Setting. Informants were purposely selected from a Danish population-based, age-specific cohort study conducted in the county of...... Copenhagen with people born in 1936. Subjects. Women in their sixties. Results. Women who perceived a current risk of osteoporosis tended to reduce their physical activity in an attempt to reduce the risk of bone damage. This behaviour was related to the imagined fragility of the bones (the risk inside the...... body), and the actual situations (the risk outside the body), including places and activities. Knowledge of a reduced bone mass reinforced the women's uncertainty about what their bones could endure. Experiences managing physical activity without injury resulted in reinterpretations of their risk of...

  9. Students' Motivation, Physical Activity Levels, & Health-Related Physical Fitness in Middle School Physical Education

    Gao, Zan; Newton, Maria; Carson, Russell L.

    2008-01-01

    This study examines the predictive utility of students' motivation (self-efficacy and task values) to their physical activity levels and health-related physical fitness (cardiovascular fitness and muscular strength/endurance) in middle school fitness activity classes. Participants (N = 305) responded to questionnaires assessing their self-efficacy…

  10. Methanolic Extract of Clinacanthus nutans Exerts Antinociceptive Activity via the Opioid/Nitric Oxide-Mediated, but cGMP-Independent, Pathways.

    Abdul Rahim, Mohammad Hafiz; Zakaria, Zainul Amiruddin; Mohd Sani, Mohd Hijaz; Omar, Maizatul Hasyima; Yakob, Yusnita; Cheema, Manraj Singh; Ching, Siew Mooi; Ahmad, Zuraini; Abdul Kadir, Arifah

    2016-01-01

    The objectives of the present study were to determine the mechanisms of antinociceptive effect of methanol extract of Clinacanthus nutans (Acanthaceae) leaves (MECN) using various animal nociceptive models. The antinociceptive activity of orally administered 10% DMSO, 100 mg/kg acetylsalicylic acid (ASA), 5 mg/kg morphine, or MECN (100, 250, and 500 mg/kg) was determined using the acetic acid-induced abdominal constriction (ACT), formalin-induced paw licking (FT), and hot plate tests (HPT). The role of opioid and nitric oxide/cyclic guanosine monophosphate (NO/cGMP) systems was also investigated. The results showed that MECN produced a significant (p 500 mg/kg or 227.7 mg/kg, respectively. This antinociceptive activity was fully antagonized by naloxone (a nonselective opioid antagonist) but was partially reversed by l-arginine (l-arg; a nitric oxide [NO] precursor), Nω-nitro-l-arginine methyl ester hydrochloride (l-NAME; an NO synthase inhibitor), or their combinations thereof. In contrast, 1H-[1,2,4]oxadiazole[4,3-a]quinoxalin-1-one (ODQ; a soluble guanylyl cyclase inhibitor) enhanced the extract's antinociception. UHPLC analysis revealed the presence of several flavonoid-based compounds with antinociceptive action. In conclusion, MECN exerted the peripherally and centrally mediated antinociceptive activity via the modulation of the opioid/NO-mediated, but cGMP-independent, systems. PMID:27190528

  11. Methanolic Extract of Clinacanthus nutans Exerts Antinociceptive Activity via the Opioid/Nitric Oxide-Mediated, but cGMP-Independent, Pathways

    Mohammad Hafiz Abdul Rahim

    2016-01-01

    Full Text Available The objectives of the present study were to determine the mechanisms of antinociceptive effect of methanol extract of Clinacanthus nutans (Acanthaceae leaves (MECN using various animal nociceptive models. The antinociceptive activity of orally administered 10% DMSO, 100 mg/kg acetylsalicylic acid (ASA, 5 mg/kg morphine, or MECN (100, 250, and 500 mg/kg was determined using the acetic acid-induced abdominal constriction (ACT, formalin-induced paw licking (FT, and hot plate tests (HPT. The role of opioid and nitric oxide/cyclic guanosine monophosphate (NO/cGMP systems was also investigated. The results showed that MECN produced a significant (p500 mg/kg or 227.7 mg/kg, respectively. This antinociceptive activity was fully antagonized by naloxone (a nonselective opioid antagonist but was partially reversed by L-arginine (L-arg; a nitric oxide [NO] precursor, Nω-nitro-L-arginine methyl ester hydrochloride (L-NAME; an NO synthase inhibitor, or their combinations thereof. In contrast, 1H-[1,2,4]oxadiazole[4,3-a]quinoxalin-1-one (ODQ; a soluble guanylyl cyclase inhibitor enhanced the extract’s antinociception. UHPLC analysis revealed the presence of several flavonoid-based compounds with antinociceptive action. In conclusion, MECN exerted the peripherally and centrally mediated antinociceptive activity via the modulation of the opioid/NO-mediated, but cGMP-independent, systems.

  12. Methanolic Extract of Clinacanthus nutans Exerts Antinociceptive Activity via the Opioid/Nitric Oxide-Mediated, but cGMP-Independent, Pathways

    Abdul Rahim, Mohammad Hafiz; Zakaria, Zainul Amiruddin; Mohd Sani, Mohd Hijaz; Omar, Maizatul Hasyima; Yakob, Yusnita; Cheema, Manraj Singh; Ching, Siew Mooi; Ahmad, Zuraini; Abdul Kadir, Arifah

    2016-01-01

    The objectives of the present study were to determine the mechanisms of antinociceptive effect of methanol extract of Clinacanthus nutans (Acanthaceae) leaves (MECN) using various animal nociceptive models. The antinociceptive activity of orally administered 10% DMSO, 100 mg/kg acetylsalicylic acid (ASA), 5 mg/kg morphine, or MECN (100, 250, and 500 mg/kg) was determined using the acetic acid-induced abdominal constriction (ACT), formalin-induced paw licking (FT), and hot plate tests (HPT). The role of opioid and nitric oxide/cyclic guanosine monophosphate (NO/cGMP) systems was also investigated. The results showed that MECN produced a significant (p 500 mg/kg or 227.7 mg/kg, respectively. This antinociceptive activity was fully antagonized by naloxone (a nonselective opioid antagonist) but was partially reversed by l-arginine (l-arg; a nitric oxide [NO] precursor), Nω-nitro-l-arginine methyl ester hydrochloride (l-NAME; an NO synthase inhibitor), or their combinations thereof. In contrast, 1H-[1,2,4]oxadiazole[4,3-a]quinoxalin-1-one (ODQ; a soluble guanylyl cyclase inhibitor) enhanced the extract's antinociception. UHPLC analysis revealed the presence of several flavonoid-based compounds with antinociceptive action. In conclusion, MECN exerted the peripherally and centrally mediated antinociceptive activity via the modulation of the opioid/NO-mediated, but cGMP-independent, systems.

  13. Physical activity in patients with anorexia nervosa.

    Achamrah, Najate; Coëffier, Moïse; Déchelotte, Pierre

    2016-05-01

    Anorexia nervosa (AN) is often associated with physical hyperactivity. Recent studies have established links between anorexia and hyperactivity, suggesting the existence of commonalities in neural pathways. How physical activity should be managed during the clinical care of patients with anorexia remains controversial. This review first focuses on the implication of hyperactivity in the pathophysiology of AN. Hyperactivity during refeeding of patients with AN has been associated with increased energy needs to achieve weight gain, poorer clinical outcome, longer hospitalization, and increased psychiatric comorbidity. This typically leads to the prescription of bed rest. However, current knowledge suggests that preserving some kind of physical activity during refeeding of patients with AN should be safe and beneficial for the restoration of body composition, the preservation of bone mineral density, and the management of mood and anxiety. In the absence of standardized guidelines, it is suggested here that physical activity during refeeding of patients with AN should be personalized according to the physical and mental status of each patient. More research is needed to assess whether programmed physical activity may be a beneficial part of the treatment of AN. PMID:27052638

  14. Validation of reported physical activity for cholesterol control using two different physical activity instruments

    Amy Z Fan

    2009-08-01

    Full Text Available Amy Z Fan1, Sandra A Ham2, Shravani Reddy Muppidi3, Ali H Mokdad41Behavioral Surveillance Branch, Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion; 2Physical Activity and Health Branch, Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA; 3College of Public Health, University of Georgia, Athens, GA, USA; 4Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USAAbstract: The National Cholesterol Education Program recommends increasing physical activity to improve cholesterol levels and overall cardiovascular health. We examined whether US adults who reported increasing their physical activity to control or lower blood cholesterol following physician’s advice or on their own efforts had higher levels of physical activity than those who reported that they did not. We used data from the National Health and Nutrition Examination Survey 2003–2004, which implemented two physical activity assessment instruments. The physical activity questionnaire (PAQ assessed self-reported frequency, intensity, and duration of leisure-time, household, and transportation-related physical activity in the past month. Physical movement was objectively monitored using a waist accelerometer that assessed minute-by-minute intensity (counts of movement/minute during waking time over a 7-day period. We adjusted our analysis for age, gender, race/ethnicity, educational attainment, and body mass index. Participants who reported increasing physical activity to control blood cholesterol had more PAQ-assessed physical activity and more accelerometer-assessed active days per week compared to those who did not. However, there were no significant differences in cholesterol levels between comparison groups. These findings suggest that self-report of exercising

  15. Physical activity and physical activity induced energy expenditure in humans: measurement, determinants, and effects

    KlaasRWesterterp

    2013-01-01

    Physical activity is defined as any bodily movement produced by skeletal muscles that results in energy expenditure. The doubly labelled water method for the measurement of total energy expenditure, in combination with resting energy expenditure, is the reference for physical activity under free-living conditions. To compare the physical activity level (PAL) within and between species, total energy expenditure is divided by resting energy expenditure resulting in a figure without dimension. T...

  16. Peer-delivered physical activity interventions: an overlooked opportunity for physical activity promotion

    Ginis, Kathleen A Martin; Nigg, Claudio R; Smith, Alan L.

    2013-01-01

    The purpose of this systematic review was to catalogue and synthesize published studies that have examined the effects of peer-delivered physical activity interventions on physical activity behavior. Ten published studies were identified that met the inclusion criteria. The following information was extracted from each study: study design and duration; characteristics of the sample, peers, and interventions; and physical activity outcomes. In all articles reporting within-groups analyses, pee...

  17. Contribution of physical education to overall physical activity.

    Meyer, U; Roth, R; Zahner, L; Gerber, M; Puder, J J; Hebestreit, H; Kriemler, S

    2013-10-01

    For many children, physical activity (PA) during physical education (PE) lessons provides an important opportunity for being physically active. Although PA during PE has been shown to be low, little is known about the contribution of PA during PE to overall PA. The aim was therefore to assess children's PA during PE and to determine the contribution of PE to overall PA with special focus on overweight children. Accelerometer measurements were done in 676 children (9.3 ± 2.1 years) over 4-7 days in 59 randomly selected classes. Moderate-and-vigorous PA (MVPA; ≥ 2000 counts/min) during PE (MVPAPE), overall MVPA per day (MVPADAY), and a comparison of days with and without PE were calculated by a regression model with gender, grade, and weight status (normal vs overweight) as fixed factors and class as a random factor. Children spent 32.8 ± 15.1% of PE time in MVPA. Weight status was not associated to MVPAPE . MVPAPE accounted for 16.8 ± 8.5% of MVPADAY, and 17.5 ± 8.2% in overweight children. All children were more active on days with PE than on days without PE (differences: 16.1 ± 29.0 min of MVPADAY; P ≤ 0.001; 13.7 ± 28.0 min for overweight children). Although MVPAPE was low, PE played a considerable role in providing PA and was not compensated by reducing extracurricular MVPA. PMID:22151355

  18. Nutrition and Physical Activity in CKD patients

    Adamasco Cupisti

    2014-07-01

    Full Text Available Chronic kidney disease (CKD patients are at risk for protein-energy wasting, abnormal body composition and impaired physical capacity. These complications lead to increased risk of hospitalization, morbidity and mortality.In CKD patient as well as in healthy people, there is a close association between nutrition and physical activity. Namely, inadequate nutrient (energy intake impairs physical performance thus favoring a sedentary lifestyle: this further contributes to loss of muscle strength and mass, which limit the quality of life and rehabilitation of CKD patients. In CKD as well as in end-stage-renal-disease patients, regular physical activity coupled with adequate energy and protein intake counteracts protein-energy wasting and related comorbidity and mortality. In summary, exercise training can positively influence nutritional status and the perception of well-being of CKD patients and may facilitate the anabolic effects of nutritional interventions.

  19. Physical education, school physical activity, school sports and academic performance

    Shephard Roy J

    2008-02-01

    Full Text Available Abstract Background The purpose of this paper is to review relationships of academic performance and some of its determinants to participation in school-based physical activities, including physical education (PE, free school physical activity (PA and school sports. Methods Linkages between academic achievement and involvement in PE, school PA and sport programmes have been examined, based on a systematic review of currently available literature, including a comprehensive search of MEDLINE (1966 to 2007, PSYCHINFO (1974 to 2007, SCHOLAR.GOOGLE.COM, and ERIC databases. Results Quasi-experimental data indicate that allocating up to an additional hour per day of curricular time to PA programmes does not affect the academic performance of primary school students negatively, even though the time allocated to other subjects usually shows a corresponding reduction. An additional curricular emphasis on PE may result in small absolute gains in grade point average (GPA, and such findings strongly suggest a relative increase in performance per unit of academic teaching time. Further, the overwhelmingly majority of such programmes have demonstrated an improvement in some measures of physical fitness (PF. Cross-sectional observations show a positive association between academic performance and PA, but PF does not seem to show such an association. PA has positive influences on concentration, memory and classroom behaviour. Data from quasi-experimental studies find support in mechanistic experiments on cognitive function, pointing to a positive relationship between PA and intellectual performance. Conclusion Given competent providers, PA can be added to the school curriculum by taking time from other subjects without risk of hindering student academic achievement. On the other hand, adding time to "academic" or "curricular" subjects by taking time from physical education programmes does not enhance grades in these subjects and may be detrimental to health.

  20. Active for Life: A Work-based Physical Activity Program

    Beverly B. Green, MD, MPH

    2007-07-01

    Full Text Available BackgroundThe American Cancer Society’s Active for Life is a worksite wellness program that encourages employees to be physically active. This paper reports the experience of implementing Active for Life in a worksite setting and its longer-term impact on physical activity.ContextThe Active for Life intervention was provided to employees at Group Health Cooperative, a nonprofit health care system in the Pacific Northwest with 9800 employees.MethodsPosters, newsletters, health fairs, and site captains promoted enrollment in Active for Life. Interventions included goal-setting, self-monitoring, incentives, and team competition. Preprogram and postprogram changes in physical activity were assessed at baseline, 10 weeks, and 6 months.ConsequencesActive for Life was offered to 3624 employees, and 1167 (32% enrolled; 565 (48% completed all three surveys. At 10 weeks, all physical activity measures increased significantly. The proportion of employees meeting the guideline of the Centers for Disease and Control and Prevention for physical activity increased from 34% to 48% (P < .01. At the 6-month follow-up, the frequency of exercising enough to work up a sweat (P < .01 remained significantly increased, but other measures of physical activity declined toward baseline.InterpretationA 10-week worksite program implemented at multiple facilities increased physical activity by the end of the intervention, but these changes were not sustained over time. Future interventions might include extending the length of the program, repeating the program, or adding larger economic incentives over time. Any such alternative models should be carefully evaluated, using a randomized design if possible.

  1. Racial, Ethnic and Gender Differences in Physical Activity

    Henry Saffer; Dhaval M. Dave; Michael Grossman

    2011-01-01

    This study examines racial, ethnic and gender differentials in physical activity. Individuals engage in physical activity during leisure-time and also during in many other activities such as walking to work, home maintenance, shopping and child care. Physical activity also occurs on the job is this is referred to as work physical activity. Prior studies have shown that non-work physical activity has a positive impact on health while work physical activity has a negative impact on health. Many...

  2. Physical Activity: Economic and Policy Factors

    Melayne M. McInnes; Shinogle, Judith A.

    2009-01-01

    While much research has focused on the costs of obesity and economic factors that drive obesity growth, little economic research has examined the factors that contribute to obesity -- physical inactivity and poor nutrition. This paper will examine correlates and predictors of physical activity over time with emphasis on economic factors. We use data for adults from the 2000-2005 Behavioral Risk Factor Surveillance System (BRFSS) survey that includes state and county codes for each individual ...

  3. Physical Activity Index among Malaysian Youth

    Norlena Salamudin; Mohd Taib Harun

    2013-01-01

    Over the last several years, physical inactivity has increasingly been recognized as a major health risk among Malaysians. The Government of Malaysia under the Ministry of Youth has adopted many programs aiming at keeping the nation healthy. Among such programs are Malaysia Cergas and RakanSukan. Trends in the physical activity levels and participation patterns of Malaysians has never been researched or monitored. Thus, there is no available evidence to serve as a foundation for decision maki...

  4. Activity report of Reactor Physics Division - 1991

    The reseach and development (R and D) activities of the Reactor Physics Division of Indira Gandhi Centre for Atomic Research (IGCAR), Kalpakkam during 1991 are reported. The activites are arranged under the headings : Nuclear Data Proceeding and Validation, Core Physics and Operation studies, Reactor Kinetics and Safety analysis, Reactor Noise Analysis and Radiation Transport and Shielding studies. List of publications is given at the end. (author). figs., tabs., r efs

  5. The place of physical activity in the WHO Global Strategy on Diet and Physical Activity

    Craig Cora L

    2005-08-01

    Full Text Available Abstract In an effort to reduce the global burden of non-communicable disease, the World Health Organization released a Global Strategy for Diet and Physical Activity in May 2004. This commentary reports on the development of the strategy and its importance specifically for physical activity-related work of NGOs and researchers interested in increasing global physical activity participation. Sparked by its work on global efforts to target non-communicable disease prevention in 2000, the World Health Organization commissioned a global strategy on diet and physical activity. The physical activity interest followed efforts that had led to the initial global "Move for Health Day" in 2002. WHO assembled a reference group for the global strategy, and a regional consultation process with countries was undertaken. Underpinning the responses was the need for more physical activity advocacy; partnerships outside of health including urban planning; development of national activity guidelines; and monitoring of the implementation of the strategy. The consultation process was an important mechanism to confirm the importance and elevate the profile of physical activity within the global strategy. It is suggested that separate implementation strategies for diet and physical activity may be needed to work with partner agencies in disparate sectors (e.g. urban planning for physical activity, agriculture for diet. International professional societies are well situated to make an important contribution to global public health by advocating for the importance of physical activity among risk factors; developing international measures of physical activity and global impacts of inactivity; and developing a global research and intervention agenda.

  6. Activity report of Reactor Physics Division - 1988

    This report highlights the progress of activities carried out during the year 1988 in Reactor Physics Division in the form of brief summaries. The topics are organised under the following subject categories:(1) nuclear data evaluation , processing and validation, (2) core physics and analysis, (3) reactor kinetics and safety analysis, (4) noise analysis and (5) radiation transport and shielding. List of publications by the members of the Division and the Reactor Physics Seminars held during the year 1988, is included at the end of report. (author). refs., figs., tabs

  7. Is enhanced physical activity possible using active videogames?

    Our research indicated that 10– to 12-year-old children receiving two active Wii (TM)(Nintendo (R); Nintendo of America, Inc., Redmond, WA) console videogames were no more physically active than children receiving two inactive videogames. Research is needed on how active videogames may increase phys...

  8. Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway

    Wang, J. [The First Affiliated Hospital, Liaoning Medical University, Jinzhou (China); Key Laboratory of Cardiovascular and Cerebrovascular Drug Research, Liaoning Province, Liaoning Medical University, Jinzhou (China); Lu, M.L.; Dai, H.L.; Zhang, S.P.; Wang, H.X. [Key Laboratory of Cardiovascular and Cerebrovascular Drug Research, Liaoning Province, Liaoning Medical University, Jinzhou (China); Wei, N. [The First Affiliated Hospital, Liaoning Medical University, Jinzhou (China)

    2014-12-12

    This study investigated the in vitro and in vivo antiproliferative activity of esculetin against hepatocellular carcinoma, and clarified its potential molecular mechanisms. Cell viability was determined by the MTT (tetrazolium) colorimetric assay. In vivo antitumor activity of esculetin was evaluated in a hepatocellular carcinoma mouse model. Seventy-five C57BL/6J mice were implanted with Hepa1-6 cells and randomized into five groups (n=15 each) given daily intraperitoneal injections of vehicle (physiological saline), esculetin (200, 400, or 700 mg·kg{sup -1}·day{sup -1}), or 5-Fu (200 mg·kg{sup -1}·day{sup -1}) for 15 days. Esculetin significantly decreased tumor growth in mice bearing Hepa1-6 cells. Tumor weight was decreased by 20.33, 40.37, and 55.42% with increasing doses of esculetin. Esculetin significantly inhibited proliferation of HCC cells in a concentration- and time-dependent manner and with an IC{sub 50} value of 2.24 mM. It blocked the cell cycle at S phase and induced apoptosis in SMMC-7721 cells with significant elevation of caspase-3 and caspase-9 activity, but did not affect caspase-8 activity. Moreover, esculetin treatment resulted in the collapse of mitochondrial membrane potential in vitro and in vivo accompanied by increased Bax expression and decreased Bcl-2 expression at both transcriptional and translational levels. Thus, esculetin exerted in vitro and in vivo antiproliferative activity in hepatocellular carcinoma, and its mechanisms involved initiation of a mitochondrial-mediated, caspase-dependent apoptosis pathway.

  9. Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway

    J. Wang

    2015-03-01

    Full Text Available This study investigated the in vitro and in vivo antiproliferative activity of esculetin against hepatocellular carcinoma, and clarified its potential molecular mechanisms. Cell viability was determined by the MTT (tetrazolium colorimetric assay. In vivo antitumor activity of esculetin was evaluated in a hepatocellular carcinoma mouse model. Seventy-five C57BL/6J mice were implanted with Hepa1-6 cells and randomized into five groups (n=15 each given daily intraperitoneal injections of vehicle (physiological saline, esculetin (200, 400, or 700 mg·kg-1·day-1, or 5-Fu (200 mg·kg-1·day-1 for 15 days. Esculetin significantly decreased tumor growth in mice bearing Hepa1-6 cells. Tumor weight was decreased by 20.33, 40.37, and 55.42% with increasing doses of esculetin. Esculetin significantly inhibited proliferation of HCC cells in a concentration- and time-dependent manner and with an IC50 value of 2.24 mM. It blocked the cell cycle at S phase and induced apoptosis in SMMC-7721 cells with significant elevation of caspase-3 and caspase-9 activity, but did not affect caspase-8 activity. Moreover, esculetin treatment resulted in the collapse of mitochondrial membrane potential in vitro and in vivo accompanied by increased Bax expression and decreased Bcl-2 expression at both transcriptional and translational levels. Thus, esculetin exerted in vitro and in vivo antiproliferative activity in hepatocellular carcinoma, and its mechanisms involved initiation of a mitochondrial-mediated, caspase-dependent apoptosis pathway.

  10. Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway

    This study investigated the in vitro and in vivo antiproliferative activity of esculetin against hepatocellular carcinoma, and clarified its potential molecular mechanisms. Cell viability was determined by the MTT (tetrazolium) colorimetric assay. In vivo antitumor activity of esculetin was evaluated in a hepatocellular carcinoma mouse model. Seventy-five C57BL/6J mice were implanted with Hepa1-6 cells and randomized into five groups (n=15 each) given daily intraperitoneal injections of vehicle (physiological saline), esculetin (200, 400, or 700 mg·kg-1·day-1), or 5-Fu (200 mg·kg-1·day-1) for 15 days. Esculetin significantly decreased tumor growth in mice bearing Hepa1-6 cells. Tumor weight was decreased by 20.33, 40.37, and 55.42% with increasing doses of esculetin. Esculetin significantly inhibited proliferation of HCC cells in a concentration- and time-dependent manner and with an IC50 value of 2.24 mM. It blocked the cell cycle at S phase and induced apoptosis in SMMC-7721 cells with significant elevation of caspase-3 and caspase-9 activity, but did not affect caspase-8 activity. Moreover, esculetin treatment resulted in the collapse of mitochondrial membrane potential in vitro and in vivo accompanied by increased Bax expression and decreased Bcl-2 expression at both transcriptional and translational levels. Thus, esculetin exerted in vitro and in vivo antiproliferative activity in hepatocellular carcinoma, and its mechanisms involved initiation of a mitochondrial-mediated, caspase-dependent apoptosis pathway

  11. Effect of physical activities on obese adolescents

    Sergio Roberto Adriano Prati

    2008-06-01

    Full Text Available The increase in body fat levels associated with the decrease in physical activities in adolescents has been the concern of recent researches because there is a strong correlation between the growing number of early-age obesity cases and the appearance of cardiovascular diseases, diabetes, hypertension, behavior problems and even death when not treated in time. So this study aimed to analyze through a bibliographical investigation some of the factors that cause obesity in adolescents and propose alternative physical activities to help in the treatment and minimize the problem. The analysis showed that programmed, controlled and adequate physical activities, associated with changes in behavior and lifestyle, may revert obesity condition and improve life quality of these adolescents.

  12. Prescribing physical activity for older adults.

    Ross, Karen M; Teasdale, Thomas A

    2005-09-01

    Physicians and other healthcare providers must disseminate the message promoting physical activity among all of their patients, especially frail older adults. Some degree of physical activity is always preferable to a sedentary life. The goals of physical activity counseling are to provide concrete information, clear and consistent recommendations, and to recognize barriers that older adults face in initiating and maintaining a program. Tailoring the message based on their patient's health and functional status is paramount and counseling should be ongoing and included at every visit. Focusing on what has been described as "functional fitness," such as walking, transferring (up and down from chair, in and out of car, up and down stairs) in order to more easily complete tasks of daily living, should also be stressed. Medical school curricula will need to address this deficiency of practicing physicians by enhancing this area of training for optimal disease prevention, chronic disease management and health promotion. PMID:16295975

  13. Children's Physical Activity Behavior during School Recess

    Pawlowski, Charlotte Skau; Andersen, Henriette Bondo; Troelsen, Jens;

    2016-01-01

    Schoolyards are recognized as important settings for physical activity interventions during recess. However, varying results have been reported. This pilot study was conducted to gain in-depth knowledge of children's physical activity behavior during recess using a mixed-methods approach combining...... participated in go-along group interviews, and recess behavior was observed using an ethnographical participant observation approach. All data were analyzed separated systematically answering the Five W Questions. Children were categorized into Low, Middle and High physical activity groups and these groups...... were predominantly staying in three different locations during recess: school building, schoolyard and field, respectively. Mostly girls were in the building remaining in there because of a perceived lack of attractive outdoor play facilities. The children in the schoolyard were predominantly girls who...

  14. The antigonadotropic activity of a 19-nor-progesterone derivative is exerted both at the hypothalamic and pituitary levels in women.

    Couzinet, B; Young, J; Kujas, M; Meduri, G; Brailly, S; Thomas, J L; Chanson, P; Schaison, G

    1999-11-01

    We have previously shown in postmenopausal women that a 19-nor-progesterone derivative, nomegestrol acetate (NOMA) had a strong antigonadotropic activity and that this effect was not mediated via the androgen receptor. The aim of the present study was to further assess the action of this progestin on gonadotropin secretion in women. To demonstrate at which level of the hypothalamo-pituitary-ovarian axis the gonadotropin inhibition was exerted, 10 normally cycling (NC) women, 3 women with a gonadotropin-independent ovarian function [McCune-Albright (MCA) syndrome], and 5 women with functional hypothalamic amenorrhea (FHA) participated in the study. NC women were treated orally with 5 mg NOMA for 21 days, after one control cycle. Plasma estradiol (E2) and progesterone, LH, and FSH levels were measured during each cycle. A frequent sampling study (every 10 min for 4 h), followed by a classic GnRH test (100 microg, i.v.), was performed on day 11. Women with MCA were studied before, during NOMA, and after long-acting GnRH agonist administration. In women with FHA, pulsatile GnRH (20 microg s.c., every 90 min) was given for two cycles with or without NOMA (5 mg for 21 days). In all NC women, ovulation was suppressed by NOMA. Mean plasma LH levels, LH pulse frequency, and the LH response to exogenous GnRH were significantly decreased. In MCA, neither NOMA nor GnRH agonist modified multiple ovarian cysts on ultrasound or plasma E2, levels which remained elevated, ruling out a direct ovarian effect. In FHA, pulsatile GnRH administration recreated a normal ovulatory menstrual cycle. Addition of NOMA prevented the increase of plasma E2, decreased the amplitude of LH pulses, and prevented ovulation. In view of this unexpected action of NOMA at the pituitary level, seven samples of normal human female pituitaries were tested for the presence of progesterone receptor (PR) using a double labeling immunocytochemical technique. The presence of PR was detected in the seven human

  15. Alpha-momorcharin (α-MMC) exerts effective anti-human breast tumor activities but has a narrow therapeutic window in vivo.

    Cao, Dongliang; Sun, Yun; Wang, Ling; He, Qianchuan; Zheng, Juecun; Deng, Fei; Deng, Shanshan; Chang, ShuChing; Yu, XiaoPing; Li, Minhui; Meng, Yao; Jin, Jiagui; Shen, Fubing

    2015-01-01

    Alpha-momorcharin (α-MMC), a ribosome inactivating protein (RIP) extracted from the seeds of Momordica charantia, exerts anti-tumor, antiviral, and anti-fungal activities. However, α-MMC has an obvious toxicity that limits its clinical application. We examined the effect of α-MMC on the inhibition of human breast cancer and assessed its general toxicity to find the therapeutic window in vivo for its potential clinical use. It was purified using column chromatography, and then injected into the xenograft nude mouse model induced by MDA-MB-231 and MCF-7. The anti-tumor efficacy was evaluated with T/C%. Next, the α-MMC was injected at a series of doses to Balb/C mice to assess its general toxicity. The MTT assay, the apoptosis test, and the cell cycle inhibition of α-MMC in human breast cancer cells were performed. In the xenografted tumors induced by MDA-MB-231 and MCF-7, α-MMC exerted an obvious inhibition effects on tumor growth at the dosage of 1.2mg/kg and 0.8 mg/kg. For in vivo toxicity experiments of α-MMC in Balb/C mice, the minimal toxic dose of α-MMC was 1.2mg/kg. Alpha-MMC induced apoptosis by increasing caspase3 activities, and the cell cycle was arrested at the G0/G1 or G2/M phases. The measurements of IC50 were 15.07 μg/mL, 33.66 μg/mL, 42.94 μg/mL for MDA-MB-231, MCF-7 and MDA-MB-453 respectively. Alpha-MMC exhibits anti-tumor effects in human breast cancer in vivo and in vitro. It inhibits breast cancer cells through the inhibition of tumor growth and induction of cell apoptosis. However, due to its obvious toxicity, α-MMC has a relatively narrow therapeutic window in vivo. PMID:25447153

  16. Are Preschool Children Active Enough? Objectively Measured Physical Activity Levels

    Cardon, Greet M.; De Bourdeaudhuij, Ilse M. M.

    2008-01-01

    The present study aimed to describe accelerometer-based physical activity levels in 4- and 5-year-old children (N = 76) on 2 weekdays and 2 weekend days. The children were sedentary for 9.6 hr (85%) daily, while they engaged in moderate to vigorous physical activity (MVPA) for 34 min (5%). Only 7% of the children engaged in MVPA for 60 min per…

  17. Cardiovascular Reactivity, Stress, and Physical Activity

    Chun-Jung eHuang

    2013-11-01

    Full Text Available Psychological stress has been proposed as a major contributor to the progression of cardiovascular disease (CVD. Acute mental stress can activate the sympathetic-adrenal-medullary (SAM axis, eliciting the release of catecholamines (NE and EPI resulting in the elevation of heart rate (HR and blood pressure (BP. Combined stress (psychological and physical can exacerbate these cardiovascular responses, which may partially contribute to the elevated risk of CVD and increased proportionate mortality risks experienced by some occupations (e.g., firefighting and law enforcement. Studies have supported the benefits of physical activity on physiological and psychological health, including the cardiovascular response to acute stress. Aerobically trained individuals exhibit lower sympathetic nervous system (e.g., HR reactivity and enhanced cardiovascular efficiency (e.g., lower vascular reactivity and decreased recovery time in response to physical and/or psychological stress. In addition, resistance training has been demonstrated to attenuate cardiovascular responses and improve mental health. This review will examine stress-induced cardiovascular reactivity and plausible explanations for how exercise training and physical fitness (aerobic and resistance exercise can attenuate cardiovascular responses to stress. This enhanced functionality may facilitate a reduction in the incidence of stroke and myocardial infarction. Finally, this review will also address the interaction of obesity and physical activity on cardiovascular reactivity and CVD.

  18. Synchronized personalized music audio-playlists to improve adherence to physical activity among patients participating in a structured exercise program: a proof-of-principle feasibility study

    Alter, David A.; O’Sullivan, Mary; Oh, Paul I.; Redelmeier, Donald A.; Marzolini, Susan; Liu, Richard; Forhan, Mary; Silver, Michael; Goodman, Jack M.; Bartel, Lee R

    2015-01-01

    Background Preference-based tempo-pace synchronized music has been shown to reduce perceived physical activity exertion and improve exercise performance. The extent to which such strategies can improve adherence to physical activity remains unknown. The objective of the study is to explore the feasibility and efficacy of tempo-pace synchronized preference-based music audio-playlists on adherence to physical activity among cardiovascular disease patients participating in a cardiac rehabilitati...

  19. Evaluation of methods to assess physical activity

    Leenders, Nicole Y. J. M.

    Epidemiological evidence has accumulated that demonstrates that the amount of physical activity-related energy expenditure during a week reduces the incidence of cardiovascular disease, diabetes, obesity, and all-cause mortality. To further understand the amount of daily physical activity and related energy expenditure that are necessary to maintain or improve the functional health status and quality of life, instruments that estimate total (TDEE) and physical activity-related energy expenditure (PAEE) under free-living conditions should be determined to be valid and reliable. Without evaluation of the various methods that estimate TDEE and PAEE with the doubly labeled water (DLW) method in females there will be eventual significant limitations on assessing the efficacy of physical activity interventions on health status in this population. A triaxial accelerometer (Tritrac-R3D, (TT)), an uniaxial (Computer Science and Applications Inc., (CSA)) activity monitor, a Yamax-Digiwalker-500sp°ler , (YX-stepcounter), by measuring heart rate responses (HR method) and a 7-d Physical Activity Recall questionnaire (7-d PAR) were compared with the "criterion method" of DLW during a 7-d period in female adults. The DLW-TDEE was underestimated on average 9, 11 and 15% using 7-d PAR, HR method and TT. The underestimation of DLW-PAEE by 7-d PAR was 21% compared to 47% and 67% for TT and YX-stepcounter. Approximately 56% of the variance in DLW-PAEE*kgsp{-1} is explained by the registration of body movement with accelerometry. A larger proportion of the variance in DLW-PAEE*kgsp{-1} was explained by jointly incorporating information from the vertical and horizontal movement measured with the CSA and Tritrac-R3D (rsp2 = 0.87). Although only a small amount of variance in DLW-PAEE*kgsp{-1} is explained by the number of steps taken per day, because of its low cost and ease of use, the Yamax-stepcounter is useful in studies promoting daily walking. Thus, studies involving the

  20. The activity of Moscow Engineering Physics Institute

    Various information about Moscow Engineering Physics Institute (MEPhI) structure and scientific activity are discussed. The four main faculties of MEPhI: the faculty of theoretical and experimental physics, the faculty of technical physics, the faculty of automatics and electronics and the faculty of cybernetics are being written in this report. The information about the research reactors and the scientific research laboratories is also presented. The participation of MEPhI in the state scientific technological programs such as 'High energy physics', 'High-temperature superconductivity', 'Controlled thermonuclear synthesis and plasma processes'. 'Informatization', 'Security of population and industrial objects on account of hazard of natural and technogenic accidents', 'Ecology of Russia', 'Synchrotron radiation and its application', 'Future technologies, machines and productions' and others are presented too. (author)

  1. Activity report of Reactor Physics Division - 1987

    The progress of activities carried out during the year 1987 in Reactor Physics Division are highlighted in this report in the form of brief summaries. These are organised under the following subject categories: (1) Nuclear Data Evaluation, Processing and Validation, (2) Core Physics, Analysis and FBTR Studies, (3) Reactor Kinetics and Safety Analysis, (4) Noise Analysis, (5) Radiation Transport, Shielding and Statistical Physics. Finally, a list of publications made by the members of the Division and the Reactor Physics Seminars held during 1987, is included at the end of the report. The large number of internal reports prepared on the PFBR and FBTR projects indicates the relatively larger amount of work carried out for these projects during 1987. (author)

  2. BARRIERS TO PHYSICAL ACTIVITY IN THE ELDERLY

    Paulo Matias

    2015-04-01

    Full Text Available The population awareness of the physical exercise’s benefits is widely diffused. These benefits are particularly important in the elderly because, with increasing age, there is a decline of the musculoskeletal system and the maximum oxygen consumption which reduces the functional fitness of the elderly and can often lead to a significant decline in the quality of life. Despite this awareness, a large part of the population remains sedentary. It is important to know what the barriers are, so they can be circumvented in order to increase the engagement of the elderly population in existing physical activity programs.Objectives: This study aims to identify some of the personal, behavioral and environmental barriers that prevent older adults to be physically active.

  3. Acute effects of three different circuit weight training protocols on blood lactate, heart rate, and rating of perceived exertion in recreationally active women.

    Skidmore, Brook L; Jones, Margaret T; Blegen, Mark; Matthews, Tracey D

    2012-01-01

    Interval and circuit weight training are popular training methods for maximizing time-efficiency, and are purported to deliver greater physiological benefits faster than traditional training methods. Adding interval training into a circuit weight-training workout may further enhance the benefits of circuit weight training by placing increased demands upon the cardiovascular system. Our purpose was to compare acute effects of three circuit weight training protocols 1) traditional circuit weight training, 2) aerobic circuit weight training, and 3) combined circuit weight-interval training on blood lactate (BLA), heart rate (HR), and ratings of perceived exertion (RPE). Eleven recreationally active women completed 7 exercise sessions. Session 1 included measurements of height, weight, estimated VO2max, and 13 repetition maximum (RM) testing of the weight exercises. Sessions 2-4 were held on non-consecutive days for familiarization with traditional circuit weight training (TRAD), aerobic circuit weight training (ACWT), and combined circuit weight-interval training (CWIT) protocols. In sessions 5-7, TRAD, ACWT, and CWIT were performed in a randomized order ≥ 72 hr apart for measures of BLA, HR, and RPE at pre-exercise and following each of three mini-circuit weight training stations. Repeated-measures ANOVAs yielded significant interactions (p workouts into exercise programming may enhance fitness benefits and maximize time-efficiency more so than traditional circuit training methods. PMID:24150076

  4. [Effect of vibration, noise, physical exertion and unfavorable microclimate on carbohydrate metabolism in workers engaged into mining industry and machine building].

    Lapko, I V; Kir'iakov, V A; Antoshina, L I; Pavlovskaia, N A; Kondratovich, S V

    2014-01-01

    The authors studied influence of vibration, noise, physical overexertion and microclimate on carbohydrates metabolism and insulin resistance in metal mining industry workers. Findings are that vibration disease appeared to have maximal effect on insulin resistance test results and insulin level. The authors suggested biomarkers for early diagnosis of insulin resistance disorders in metal mining industry workers. PMID:25282800

  5. Addressing childhood obesity through increased physical activity.

    Hills, Andrew P; Okely, Anthony D; Baur, Louise A

    2010-10-01

    Obesity is affecting an increasing proportion of children globally. Despite an appreciation that physical activity is essential for the normal growth and development of children and prevents obesity and obesity-related health problems, too few children are physically active. A concurrent problem is that today's young people spend more time than previous generations did in sedentary pursuits, including watching television and engaging in screen-based games. Active behavior has been displaced by these inactive recreational choices, which has contributed to reductions in activity-related energy expenditure. Implementation of multifactorial solutions considered to offer the best chance of combating these trends is urgently required to redress the energy imbalance that characterizes obesity. The counterproductive 'shame and blame' mentality that apportions responsibility for the childhood obesity problem to sufferers, their parents, teachers or health-care providers needs to be changed. Instead, these groups should offer constant support and encouragement to promote appropriate physical activity in children. Failure to provide activity opportunities will increase the likelihood that the children of today will live less healthy (and possibly shorter) lives than their parents. PMID:20736922

  6. Promoting Physical Activity through Goal Setting Strategies

    Martinez, Ray

    2004-01-01

    Physical educators are used to setting specific goals for students within a given unit. Here, the author emphasizes that they should also encourage students to set their own goals. Goal setting engages students in the learning process and allows them to develop the skills that support an active lifestyle. The author presents goal setting…

  7. Physics Division activities report, 1986--1987

    1987-01-01

    This report summarizes the research activities of the Physics Division for the years 1986 and 1987. Areas of research discussed in this paper are: research on e/sup +/e/sup /minus// interactions; research on p/bar p/ interactions; experiment at TRIUMF; double beta decay; high energy astrophysics; interdisciplinary research; and advanced technology development and the SSC.

  8. Health Care Provider Physical Activity Prescription Intervention

    Josyula, Lakshmi; Lyle, Roseann

    2013-01-01

    Purpose: To examine the feasibility and impact of a health care provider’s (HCP) physical activity (PA) prescription on the PA of patients on preventive care visits. Methods: Consenting adult patients completed health and PA questionnaires and were sequentially assigned to intervention groups. HCPs prescribed PA using a written prescription only…

  9. Physics Division activities report, 1986--1987

    This report summarizes the research activities of the Physics Division for the years 1986 and 1987. Areas of research discussed in this paper are: research on e+e/sup /minus// interactions; research on p/bar p/ interactions; experiment at TRIUMF; double beta decay; high energy astrophysics; interdisciplinary research; and advanced technology development and the SSC

  10. Gene × physical activity interactions in obesity

    Ahmad, Shafqat; Rukh, Gull; Varga, Tibor V;

    2013-01-01

    Numerous obesity loci have been identified using genome-wide association studies. A UK study indicated that physical activity may attenuate the cumulative effect of 12 of these loci, but replication studies are lacking. Therefore, we tested whether the aggregate effect of these loci is diminished...

  11. A social neuroscience perspective on physical activity.

    Hall, Peter A; Elias, Lorin J; Fong, Geoffrey T; Harrison, Amabilis H; Borowsky, Ron; Sarty, Gordon E

    2008-08-01

    The objective of this investigation was to examine the cognitive characteristics of individuals who demonstrate successful and unsuccessful self-regulation of physical activity behavior. In Study 1, participants articulated 1-week intentions for physical activity and wore a triaxial accelerometer over the subsequent 7 days. Among those who were motivated to increase their physical activity, those who were most and least successful were administered an IQ test. In Study 2, a second sample of participants completed the same protocol and a smaller subset of matched participants attended a functional imaging (fMRI) session. In Study 1, successful self-regulators (SSRs) scored significantly higher than unsuccessful self-regulators (USRs) on a test of general cognitive ability, and this difference could not be accounted for by favorability of attitudes toward physical activity or conscientiousness. In Study 2, the IQ effect was replicated, with SSRs showing a full standard deviation advantage over USRs. In the imaging protocol, USRs showed heavier recruitment of cognitive resources relative to SSRs in the anterior cingulate and orbitofrontal cortex during performance of a Stroop task; SSRs showed heavier recruitment in the right dorsolateral prefrontal cortex. PMID:18723901

  12. Physical activity in obesity and metabolic syndrome.

    Strasser, Barbara

    2013-04-01

    Biological aging is typically associated with a progressive increase in body fat mass and a loss of lean body mass. Owing to the metabolic consequences of reduced muscle mass, it is understood that normal aging and/or decreased physical activity may lead to a higher prevalence of metabolic disorders. Lifestyle modification, specifically changes in diet, physical activity, and exercise, is considered the cornerstone of obesity management. However, for most overweight people it is difficult to lose weight permanently through diet or exercise. Thus, prevention of weight gain is thought to be more effective than weight loss in reducing obesity rates. A key question is whether physical activity can extenuate age-related weight gain and promote metabolic health in adults. Current guidelines suggest that adults should accumulate about 60 minutes of moderate-intensity physical activity daily to prevent unhealthy weight gain. Because evidence suggests that resistance training may promote a negative energy balance and may change body fat distribution, it is possible that an increase in muscle mass after resistance training may be a key mediator leading to better metabolic control. PMID:23167451

  13. Physical Activity and Epilepsy. What are the Rules?

    Sirven, Joseph I.; Varrato, Jay

    1999-01-01

    Exercise has important benefits for people with epilepsy, but several factors must be considered when making activity recommendations. Seizures during sports activity are rare, but physicians, coaches, and parents should know what to do if a seizure occurs. Some antiepileptic drugs may adversely affect sports performance, and exertion may reduce…

  14. The contribution of the primary school setting and physical education lessons to children's physical activity levels

    Howells, K

    2014-01-01

    The thesis research explored children’s physical activity levels that occurred within the primary school setting. It examined the contribution that Physical Education lessons make to children’s overall measured physical activity levels within the school day. It investigated children’s perceived level of physical activity and compared this with children’s physical activity measured by accelerometers. For the purpose of the thesis research, physical activity was regarded as, “any bodily movemen...

  15. Participation in physical activities and sedentary behaviour among children with physical disabilities

    Lauruschkus, Katarina

    2015-01-01

    Participating in physical activity promotes physical and mental health. Children with physical disabilities are not as physically active as other children. They tend to participate in lower intensity physical activity, choose more passive activities with less variety and have more sedentary time. The overall aim of this thesis was to gain knowledge about participation in physical activities, to identify associated factors for school and leisure time and to explore the perceived experience...

  16. Physical Activity and Beverage Consumption among Adolescents.

    Bibiloni, Maria Del Mar; Özen, Asli Emine; Pons, Antoni; González-Gross, Marcela; Tur, Josep A

    2016-01-01

    This study assessed the relationship between physical activity and beverage consumption among adolescents with a population based cross-sectional survey was carried out in the Balearic Islands, Spain (n = 1988; 12-17 years old). Body composition, educational and income level, physical activity (PA), and beverage consumption and energy intake were assessed. Sixty-two percent of adolescents engaged in >300 min/week of PA. Boys were more active than girls, younger adolescents were more active than older counterparts, low parental income was associated with physical inactivity, and time spent watching TV (including, TV, Internet or handheld cellular devices) was inversely associated with PA practice. The average beverage intake of the studied adolescents was 0.9 L/day, higher in boys than in girls. Beverage intake was positively associated with PA practice, and the highest amount of energy intake from beverages was observed in active boys and girls. Most of the studied adolescent population met the PA recommendations. Gender, age, parental income, and time spent watching TV were significant determinants of PA. Type and amount of beverages drunk varied according to gender and PA, and general daily total beverage intake was lower than recommended adequate fluid intake. PA behavior should be considered when analyzing beverage consumption in adolescents. PMID:27347993

  17. Physical Activity and Beverage Consumption among Adolescents

    Maria del Mar Bibiloni

    2016-06-01

    Full Text Available This study assessed the relationship between physical activity and beverage consumption among adolescents with a population based cross-sectional survey was carried out in the Balearic Islands, Spain (n = 1988; 12–17 years old. Body composition, educational and income level, physical activity (PA, and beverage consumption and energy intake were assessed. Sixty-two percent of adolescents engaged in >300 min/week of PA. Boys were more active than girls, younger adolescents were more active than older counterparts, low parental income was associated with physical inactivity, and time spent watching TV (including, TV, Internet or handheld cellular devices was inversely associated with PA practice. The average beverage intake of the studied adolescents was 0.9 L/day, higher in boys than in girls. Beverage intake was positively associated with PA practice, and the highest amount of energy intake from beverages was observed in active boys and girls. Most of the studied adolescent population met the PA recommendations. Gender, age, parental income, and time spent watching TV were significant determinants of PA. Type and amount of beverages drunk varied according to gender and PA, and general daily total beverage intake was lower than recommended adequate fluid intake. PA behavior should be considered when analyzing beverage consumption in adolescents.

  18. Leisure time physical activity and mortality

    Føns Johnsen, Nina; Ekblond, Annette; Thomsen, Birthe Lykke;

    2013-01-01

    BACKGROUND: Some studies indicate that a large part of the beneficial effect of physical activity on mortality is confined to a threshold effect of participation. METHODS: Self-reported physical activity was investigated in relation to all-cause mortality in the Danish Diet, Cancer and Health...... in sports (for women, mortality rate ratio = 0.75, 95% confidence interval = 0.69-0.81; for men, 0.78, 0.73-0.84), cycling (for women, 0.77, 0.71-0.84; for men, 0.90, 0.84-0.96), or gardening (for women, 0.84, 0.78-0.91; for men, 0.73, 0.68-0.79) and in men participating in do-it-yourself activity (0.77, 0...

  19. Review of environmental physics activities in Egypt

    Efforts and activities in Egypt serving the environment went back to 1962. At that time simultaneously were established the Atomic Fallout Laboratory at the premises of Atomic Energy Establishment in Inshas, and the Air Pollution Unitwithin the premises of the National Research Centre in Dokki. Recent activities include: radiation monitoring, atmospheric physics, renewable energy pollution control, environmental impact, etc.The article aims at reviewing environmental physics activities in Egypt ; both on governmental and non-governmental scales.The environment is one of the most vital axes of development, so the deterioration of the environment represents a major danger threatening social and economic development, the sustainability of natural resources, and human health.Recognizing this major importance and necessity of the protection of environment and its vital role in our lives, governments all over the globe began to take larger steps towards a better and healthier environment

  20. Physical Activity Recognition from Smartphone Embedded Sensors

    Prudêncio, João; Aguiar, Ana; Roetter, Daniel Enrique Lucani

    2013-01-01

    The ubiquity of smartphones has motivated efforts to use the embedded sensors to detect various aspects of user context to transparently provide personalized and contextualized services to the user. One relevant piece of context is the physical activity of the smartphone user. In this paper, we...... propose a novel set of features for distinguishing five physical activities using only sensors embedded in the smartphone. Specifically, we introduce features that are normalized using the orientation sensor such that horizontal and vertical movements are explicitly computed. We evaluate a neural network...... classifier in experiments in the wild with multiple users and hardware, we achieve accuracies above 90% for a single user and phone, and above 65% for multiple users, which is higher that similar works on the same set of activities, demonstrating the potential of our approach....

  1. Flux control exerted by mitochondrial outer membrane carnitine palmitoyltransferase over beta-oxidation, ketogenesis and tricarboxylic acid cycle activity in hepatocytes isolated from rats in different metabolic states.

    Drynan, L; Quant, P A; Zammit, V A

    1996-01-01

    The Flux Control Coefficients of mitochondrial outer membrane carnitine palmitoyltransferase (CPT I) with respect to the overall rates of beta-oxidation, ketogenesis and tricarboxylic acid cycle activity were measured in hepatocytes isolated from rats in different metabolic states (fed, 24 h-starved, starved-refed and starved/insulin-treated). These conditions were chosen because there is controversy as to whether, when significant control ceases to be exerted by CPT I over the rate of fatty oxidation [Moir and Zammit (1994) Trends Biochem. Sci. 19, 313-317], this is transferred to one or more steps proximal to acylcarnitine synthesis (e.g. decreased delivery of fatty acids to the liver) or to the reaction catalysed by mitochondrial 3-hydroxy-3-methyl-glutaryl-CoA synthase [Hegardt (1995) Biochem. Soc. Trans. 23, 486-490]. Therefore isolated hepatocytes were used in the present study to exclude the involvement of changes in the rate of delivery of non-esterified fatty acids (NEFA) to the liver, such as occur in vivo, and to ascertain whether, under conditions of constant supply of NEFA, CPT I retains control over the relevant fluxes of fatty acid oxidation to ketones and carbon dioxide, or whether control is transferred to another (intrahepatocytic) site. The results clearly show that the Flux Control Coefficients of CPT I with respect to overall beta-oxidation and ketogenesis are very high under all conditions investigated, indicating that control is not lost to another intrahepatic site during the metabolic transitions studied. The control of CPT I over tricarboxylic acid cycle activity was always very low. The significance of these findings for the integration of fatty acid and carbohydrate metabolism in the liver is discussed. PMID:8760364

  2. A Portfolio Approach to Impacting Physically Active Lifestyles

    Allen, Ray; Pulling, Andrew R.; Alpert, Amanda; Jackman, Emma

    2014-01-01

    This article presents a physical activity portfolio designed to help students manage their own fitness and health-related physical activity outside of the physical education classroom. A main goal of physical education programs is to prepare students to lead a physically active lifestyle and maintain a lifetime of health-related fitness. The…

  3. EFFECT OF EXERCISE INTENSITY ON DIFFERENTIATED AND UNDIFFERENTIATED RATINGS OF PERCEIVED EXERTION DURING CYCLE AND TREADMILL EXERCISE IN RECREATIONALLY ACTIVE AND TRAINED WOMEN

    Melinda R. Bolgar

    2010-12-01

    Full Text Available The purpose of the study is to examine the effect of aerobic exercise intensity on components of the differentiated perceived exertion model in young women performing weight bearing and non-weight bearing aerobic exercise. Subjects were 18-25 yr old women who were recreationally active (n = 19; VO2max = 33.40 ml·kg-1·min-1 and trained (N = 22; VO2max = 43.3 ml·kg-1·min-1. Subjects underwent two graded exercise tests (GXT on a treadmill and bike which were separated by 48 hours. RPE-Overall, -Legs, and -Chest, as well as oxygen uptake (VO2 and heart rate were recorded each minute. Individual regression analyses were used to identify RPE-Overall,-Legs, and -Chest at 40, 60, 80% VO2max/peak. Separate two factor (site (3 x intensity (3 ANOVAs with repeated measures on site and intensity were computed for each training status. Furthermore, RPE responses were also examined with a one factor (site (3 within subject ANOVA with repeated measure on site at the ventilatory breakpoint. For both the recreationally active and trained groups no significant differences were observed for RPE-Overall, -Legs, and -Chest during treadmill exercise. However, for cycling exercise results indicated that RPE-Legs was significantly greater at all exercise intensities than RPE-Overall and RPE-Chest for trained subjects while for recreationally active subjects RPE-Legs was only significantly higher at the highest exercise intensity. Responses at the ventilatory breakpoint during cycle exercise indicated that RPE-Legs was significantly greater than RPE-Chest and RPE-Overall for trained subjects but not for recreationally active subjects. Signal dominance was not observed at an intensity equivalent to the ventilatory breakpoint during treadmill exercise in either of the groups. In recreationally active and trained females signal dominance was demonstrated only during cycling exercise, but not during treadmill exercise. Signal integration could not be demonstrated during

  4. Adolescents’ use of the built environment for physical activity

    Oreskovic, Nicolas M.; Perrin, James M; Robinson, Alyssa I; Locascio, Joseph J.; Blossom, Jeff; Chen, Minghua L; Winickoff, Jonathan P.; Field, Alison E.; Green, Chloe; Goodman, Elizabeth

    2015-01-01

    Background: Physical activity is a health-enhancing behavior, but few adolescents achieve the recommended levels of moderate-to-vigorous physical activity. Understanding how adolescents use different built environment spaces for physical activity and activity varies by location could help in designing effective interventions to promote moderate-to-vigorous physical activity. The objective of this study was to describe the locations where adolescents engage in physical activity and compare tra...

  5. Adolescents’ use of the built environment for physical activity

    Oreskovic, Nicolas M.; Perrin, James M; Robinson, Alyssa I; Locascio, Joseph J.; Blossom, Jeff; Chen, Minghua L; Winickoff, Jonathan P.; Field, Alison E.; Green, Chloe; Goodman, Elizabeth

    2015-01-01

    Background Physical activity is a health-enhancing behavior, but few adolescents achieve the recommended levels of moderate-to-vigorous physical activity. Understanding how adolescents use different built environment spaces for physical activity and activity varies by location could help in designing effective interventions to promote moderate-to-vigorous physical activity. The objective of this study was to describe the locations where adolescents engage in physical activity and compare trad...

  6. What I Need to Know about Physical Activity and Diabetes

    ... Clinical Trials How can physical activity help me take care of my diabetes?​ Physical activity and keeping a healthy weight can help you take care of your diabetes and prevent diabetes problems. Physical ...

  7. Parental Influence on Young Children's Physical Activity

    Cheryl A. Zecevic

    2010-01-01

    Full Text Available Parents influence on their young children's physical activity (PA behaviours was examined in a sample of 102 preschool-aged children (54 boys. Questionnaires regarding family sociodemographics and physical activity habits were completed. Results showed that children who received greater parental support for activity (B=.78, P<.10 and had parents who rated PA as highly enjoyable (B=.69, P<.05 were significantly more likely to engage in one hour or more of daily PA. Being an older child (B=−.08, P<.01, having older parents (B=−.26, P<.01, and watching more than one hour of television/videos per day (B=1.55, P<.01 reduced the likelihood that a child would be rated as highly active. Children who received greater parental support for PA were 6.3 times more likely to be highly active than inactive (B=1.44, P<.05. Thus, parents can promote PA among their preschoolers, not only by limiting TV time but also by being highly supportive of their children's active pursuits.

  8. Physical Activity and Health: Does Physical Education Matter?

    Pate, Russell R.; O'Neill, Jennifer R.; McIver, Kerry L.

    2011-01-01

    Physical education has been an institution in American schools since the late 19th century, and today almost all American children are exposed to physical education classes. It has often been claimed that physical education provides important benefits to public health. The purpose of this paper is to determine if physical education increases…

  9. Physical Activity Across Adulthood and Physical Performance in Midlife Findings from a British Birth Cohort

    Cooper, R; Mishra, G D; Kuh, D.

    2011-01-01

    Background: Evidence, mainly from cross-sectional studies, suggests that physical activity is a potentially important modifiable factor associated with physical performance and strength in older age. It is unclear whether the benefits of physical activity accumulate across life or whether there are sensitive periods when physical activity is more influential.Purpose: To examine the associations of leisure-time physical activity across adulthood with physical performance and strength in midlif...

  10. Neighborhood disadvantage, physical activity barriers, and physical activity among African American breast cancer survivors

    Antwan Jones

    2015-01-01

    Higher renter rates and individual barriers both contribute to lower levels of physical activity in African American breast cancer survivors. These data suggest that the potential for constant residential turnover (via rentership and perceived barriers may increase physical inactivity even where facilities may be available.

  11. Assessment of physical activity using wearable monitors: Measures of physical activity

    Physical activitymay be defined broadly as "all bodily actions produced by the contraction of skeletal muscle that increase energy expenditure above basal level." Physical activity is a complex construct that can be classified into major categories qualitatively, quantitatively, or contextually. The...

  12. ATTITUDES TOWARD PHYSICAL ACTIVITY AND SPORT

    José Alfredo Balderrama-Ruedas; Pedro José Díaz-Domínguez; Rosa Isela Gómez-Castillo

    2014-01-01

    One of the main problems of this country is currently sedentary carrying Mexicans, top level global envelope weight and obesity, as well as problems of prosocial behavior and crime, adding the poor academic performance in the education sector, this research seeks to know the attitudes of students toward physical activation and sport within their training and performance as future teachers.This research was conducted under the qualitative approach, using the ethnographic method, using observat...

  13. Workplace physical activity interventions: a systematic review.

    Dugdill, L.; Brettle, A; Hulme, C.; McCluskey, Serena; Long, A F

    2008-01-01

    Purpose – This paper aims to report a synopsis of a recent systematic review of the literature regarding the effectiveness of workplace physical activity interventions, commissioned by the National Institute for Health and Clinical Excellence (NICE). Design/methodology/approach – A search for English-language papers published between 1996 and 2007 was conducted using 12 relevant databases and associated grey literature. Search protocols and analysis regarding study quality as recommended...

  14. Physical activity and the healthy mind.

    Shephard, R. J.

    1983-01-01

    Physicians should seek to enhance the quality rather than the quantity of human life. Physical activity programs can increase life satisfaction through an immediate increase of arousal and a long-term enhancement of self-esteem and body image. In the young child competition can cause excessive arousal, but long-term adverse effects are rare. In the adult a reduction of anxiety and stress and a general feeling of well-being reduce the frequency of minor medical complaints, generating important...

  15. Cardiovascular reactivity, stress, and physical activity

    Chun-Jung eHuang; Webb, Heather E.; Zourdos, Michael C.; Acevedo, Edmund O.

    2013-01-01

    Psychological stress has been proposed as a major contributor to the progression of cardiovascular disease (CVD). Acute mental stress can activate the sympathetic-adrenal-medullary (SAM) axis, eliciting the release of catecholamines (NE and EPI) resulting in the elevation of heart rate (HR) and blood pressure (BP). Combined stress (psychological and physical) can exacerbate these cardiovascular responses, which may partially contribute to the elevated risk of CVD and increased proportionate...

  16. Physical activity, fitness, and gray matter volume.

    Erickson, Kirk I; Leckie, Regina L; Weinstein, Andrea M

    2014-09-01

    In this review, we explore the association among physical activity, cardiorespiratory fitness, and exercise on gray matter volume in older adults. We conclude that higher cardiorespiratory fitness levels are routinely associated with greater gray matter volume in the prefrontal cortex and hippocampus and less consistently in other regions. We also conclude that physical activity is associated with greater gray matter volume in the same regions that are associated with cardiorespiratory fitness including the prefrontal cortex and hippocampus. Some heterogeneity in the literature may be explained by effect moderation by age, stress, or other factors. Finally, we report promising results from randomized exercise interventions that suggest that the volume of the hippocampus and prefrontal cortex remain pliable and responsive to moderate intensity exercise for 6 months-1 year. Physical activity appears to be a propitious method for influencing gray matter volume in late adulthood, but additional well-controlled studies are necessary to inform public policies about the potential protective or therapeutic effects of exercise on brain volume. PMID:24952993

  17. Physical activity and survival in breast cancer

    Ammitzbøll, Gunn; Søgaard, Karen; Karlsen, Randi V;

    2016-01-01

    PURPOSE: Knowledge about lifestyle factors possibly influencing survival after breast cancer (BC) is paramount. We examined associations between two types of postdiagnosis physical activity (PA) and overall survival after BC. PATIENTS AND METHODS: We used prospective data on 959 BC survivors from...... the Diet, Cancer, and Health cohort, all enrolled before diagnosis. Self-reported PA was measured as time per activity, and estimated metabolic equivalent task (MET)-hours per week were summed for each activity. We constructed measures for household, exercise, and total PA. The association between...... from all causes during the study period. In adjusted analyses, exercise PA above eight MET h/week compared to lower levels of activity was significantly associated with improved overall survival (HR, 0.68; confidence interval [CI]: 0.47-0.99). When comparing participation in exercise to non...

  18. Does a physical activity referral scheme improve the physical activity among routine primary health care patients?

    Leijon, Matti E; Bendtsen, Preben; Nilsen, Per; Festin, Karin; Ståhle, A

    2009-01-01

    Physical activity referral (PAR) schemes or concepts occur in varying forms. Because few physical activity intervention studies have been carried out in routine health care settings, it is difficult to translate research findings into daily practice. The aim of this study was to analyze the effectiveness of a PAR scheme implemented in routine primary health care. The study did not include a control group and was based on the ordinary staff's work efforts and follow-up measures. During a 2-yea...

  19. EVALUATION OF PHYSICAL ACTIVITY OF DISABLED PEOPLE BY MODIFIED INTERNATIONAL PHYSICAL ACTIVITY QUESTIONNAIRE (IPAQ)

    Boguszewski Dariusz; Adamczyk Jakub Grzegorz; Kurkowska Beata.

    2012-01-01

    Introduction. The aim of the study was an adaptation the International Physical Activity Questionnaire for disabled people moving on wheelchairs, and check and objectification of the proposed tool. Material and methods. The research covered 69 disabled people (8 women and 61 men). All group was divided into two subgroups: regularly practicing sportsmen - Group 1 and people who were not practicing any sport - Group 2. Research tool was International Physical Activity Questionnaire (short versi...

  20. Daily physical activity and type 2 diabetes: A review

    Hamasaki, Hidetaka

    2016-01-01

    Physical activity improves glycemic control and reduces the risk of cardiovascular disease (CVD) and mortality in patients with type 2 diabetes (T2D). Moderate to vigorous physical activity is recommended to manage T2D; however, patients with T2D can be physically weak, making it difficult to engage in the recommended levels of physical activity. Daily physical activity includes various activities performed during both occupational and leisure time such as walking, gardening, and housework th...

  1. Daily Physical Activity in Stable Heart Failure Patients

    Dontje, Manon L.; van der Wal, Martje H.L; Stolk, Ronald P; Brügemann, Johan; Jaarsma, Tiny; Wijtvliet, Petra E P J; van der Schans, Cees P; Greef, Mathieu H.G.

    2014-01-01

    BACKGROUND:: Physical activity is the only nonpharmacological therapy that is proven to be effective in heart failure (HF) patients in reducing morbidity. To date, little is known about the levels of daily physical activity in HF patients and about related factors. OBJECTIVE:: The objectives of this study were to (a) describe performance-based daily physical activity in HF patients, (b) compare it with physical activity guidelines, and (c) identify related factors of daily physical activity. ...

  2. THE EFFECTS OF EXERGAMING ON PHYSICAL ACTIVITY IN A THIRD-GRADE PHYSICAL EDUCATION CLASS

    Shayne, Rachel K; Fogel, Victoria A; Miltenberger, Raymond G; Koehler, Shannon

    2012-01-01

    We compared the effects of exergaming and traditional physical education on physical activity among 4 active children who were not overweight and who had experience with the exergaming activities prior to the study. Results showed that exergaming produced substantially higher percentages of physical activity and opportunity to engage in physical activity. In addition, an evaluation of the exergaming equipment showed that exergaming stations were associated with differential levels of physical...

  3. Parent participation plays an important part in promoting physical activity

    Anna-Karin Lindqvist

    2015-08-01

    Full Text Available Although physical activity (PA is an important and modifiable determinant of health, in Sweden only 15% of boys and 10% of girls aged 15 years old achieve the recommended levels of PA 7 days per week. Adolescents’ PA levels are associated with social influence exerted by parents, friends, and teachers. The purpose of this study was to describe parents’ experiences of being a part of their adolescents’ empowerment-inspired PA intervention. A qualitative interview study was performed at a school in the northern part of Sweden. A total of 10 parents were interviewed, and the collected data were analyzed with qualitative content analysis. Three subthemes were combined into one main theme, demonstrating that parents are one important part of a successful PA intervention. The life of an adolescent has many options and demands that make it difficult to prioritize PA. Although parents felt that they were important in supporting their adolescent, a successful PA intervention must have multiple components. Moreover, the parents noted that the intervention had a positive effect upon not only their adolescents’, but also their own PA. Interventions aimed at promoting PA among adolescents should include measures to stimulate parent participation, have an empowerment approach, and preferably be school-based.

  4. Australian perspective regarding recommendations for physical activity and exercise rehabilitation in pulmonary arterial hypertension

    Gabbay E

    2011-12-01

    Full Text Available Robin Fowler1–3, Sue Jenkins2,3,5, Andrew Maiorana2,4, Kevin Gain2,3,6,7, Gerry O'Driscoll7–9, Eli Gabbay1–3,7–91Advanced Lung Disease Program, Royal Perth Hospital, 2School of Physiotherapy and Curtin Health Innovation Research Institute, Curtin University, 3Lung Institute of Western Australia (LIWA, Centre for Asthma, Allergy and Respiratory Research, University of Western Australia, 4Advanced Heart Failure and Cardiac Transplant Service, Royal Perth Hospital, 5Physiotherapy Department, Sir Charles Gairdner Hospital, 6Respiratory Medicine Department, Royal Perth Hospital, 7School of Medicine, University of Western Australia, 8School of Medicine, University of Notre Dame, 9Heart and Lung Transplant Foundation of Western Australia, Perth, Western Australia, AustraliaAim: To determine the opinion of health care professionals within Australia, regarding acceptable levels of exertion and symptoms, and referral for exercise rehabilitation in patients with pulmonary arterial hypertension (PAH.Method: In 2010, 76 health care professionals at a specialist pulmonary hypertension meeting in Australia were surveyed using a self-administered questionnaire. The questionnaire included case studies of patients with PAH in World Health Organization (WHO functional classes II–IV. For each case study, respondents were asked to report their opinion regarding the acceptable level of exertion and symptoms during daily activities, and whether they would refer the patient for exercise rehabilitation. Three additional questions asked about advice in relation to four specific physical activities.Results: The response rate was 70% (n = 53. Overall, 58% of respondents recommended patients undertake daily activities 'as tolerated'. There was no consensus regarding acceptable levels of breathlessness or fatigue, but the majority of respondents considered patients should have no chest pain (73% and no more than mild light-headedness (92% during daily activities

  5. Activated coconut shell charcoal carbon using chemical-physical activation

    Budi, Esmar; Umiatin, Nasbey, Hadi; Bintoro, Ridho Akbar; Wulandari, Futri; Erlina

    2016-02-01

    The use of activated carbon from natural material such as coconut shell charcoal as metal absorbance of the wastewater is a new trend. The activation of coconut shell charcoal carbon by using chemical-physical activation has been investigated. Coconut shell was pyrolized in kiln at temperature about 75 - 150 °C for about 6 hours in producing charcoal. The charcoal as the sample was shieved into milimeter sized granule particle and chemically activated by immersing in various concentration of HCl, H3PO4, KOH and NaOH solutions. The samples then was physically activated using horizontal furnace at 400°C for 1 hours in argon gas environment with flow rate of 200 kg/m3. The surface morphology and carbon content of activated carbon were characterized by using SEM/EDS. The result shows that the pores of activated carbon are openned wider as the chemical activator concentration is increased due to an excessive chemical attack. However, the pores tend to be closed as further increasing in chemical activator concentration due to carbon collapsing.

  6. Positive Youth Development through Physical Activity: Opportunities for Physical Educators

    Hemphill, Michael A.

    2014-01-01

    As physical educators continue to advocate for school-based PE, they should also consider ways to extend their work into community settings in an effort to ensure that all kids have an opportunity to develop physical literacy. This article describes how positive youth development programs can provide an opportunity for physical educators to engage…

  7. International Centre for Theoretical Physics, Trieste: Scientific activities in 1988

    The document contains three parts. Part I is a review of the Scientific activities in 1988 with a statistical digest. Part II describes the scientific programme in Fundamental physics, Condensed matter, Atomic and molecular physics, Mathematics, Physics and energy, Physics and environment, Physics of the living state, Applied physics, Adriatico research conferences. Part III lists the publications issued in 1988. Tabs

  8. Rockets: Physical science teacher's guide with activities

    Vogt, Gregory L.; Rosenberg, Carla R. (Editor)

    1993-01-01

    This guide begins with background information sections on the history of rocketry, scientific principles, and practical rocketry. The sections on scientific principles and practical rocketry are based on Isaac Newton's three laws of motion. These laws explain why rockets work and how to make them more efficient. The background sections are followed with a series of physical science activities that demonstrate the basic science of rocketry. Each activity is designed to be simple and take advantage of inexpensive materials. Construction diagrams, materials and tools lists, and instructions are included. A brief discussion elaborates on the concepts covered in the activities and is followed with teaching notes and discussion questions. The guide concludes with a glossary of terms, suggested reading list, NASA educational resources, and an evaluation questionnaire with a mailer.

  9. Seasonal variation in leisure time physical activity.

    Uitenbroek, D G

    1993-06-01

    In this paper seasonal variation in leisure time physical activity for exercise is studied and quantified with regard to several popular exercise activities and taking the respondents gender, occupational status, and age into consideration. The analysis concerns data collected by telephone in Scotland between January 1989 and March 1992. Data from 7,202 male and 9,284 female respondents is used in the analysis; cosinor analysis using GLIM is applied. Considerable seasonal variation was found affecting both outdoor and indoor activities. During the peak phase in July, 32% of the respondents reported exercising for at least 20 min three or more times during the previous week, in the winter period this decreased to 23%. Older respondents were found to exercise more later in the year and also showed seasonal variation to a larger extent than younger respondents. This is particularly so for those respondents who exercise at a relatively high frequency. PMID:8321115

  10. Do attributes in the physical environment influence children's physical activity? A review of the literature

    Lawson Catherine T; Davison Kirsten

    2006-01-01

    Abstract Background Many youth today are physically inactive. Recent attention linking the physical or built environment to physical activity in adults suggests an investigation into the relationship between the built environment and physical activity in children could guide appropriate intervention strategies. Method Thirty three quantitative studies that assessed associations between the physical environment (perceived or objectively measured) and physical activity among children (ages 3 to...

  11. Physical Activity and the Achievement Gap among Urban Minority Youth

    Basch, Charles E.

    2011-01-01

    Objectives: To outline the prevalence and disparities of physical activity among school-aged urban minority youth, causal pathways through which low levels of physical activity and fitness adversely affects academic achievement, and proven or promising approaches for schools to increase physical activity and physical fitness among youth. Methods:…

  12. The Effect of Physical Education Climates on Elementary Students' Physical Activity Behaviors

    Wadsworth, Danielle D.; Robinson, Leah E.; Rudisill, Mary E.; Gell, Nancy

    2013-01-01

    Background: With the growing need for children from underserved populations to be physically active it is imperative to create developmentally appropriate and enjoyable physical education programs that promote physical activity. The purpose of this study was to determine the effects of mastery and performance climates on physical activity during…

  13. Activity report of Reactor Physics Section - 1985

    This Activity Report contains brief summaries of different studies made in Reactor Physics Section during the year 1985. These are presented under the headings Nuclear Data Processing and Validation, Reactor Design and Analysis, Safety and Noise Analysis, Radiation Transport and Shielding, Reactor Physics Experiments and Statistical Physics. The work on nuclear data during this period comprises primarily of validation of data of 232Th and 233U as a part of participation in the Co-ordinated Research Programme (CRP) under IAEA research contract. The most significant event during 1985 at this centre has been the first criticality of FBTR (Fast Breeder Test Reactor), which was achieved on the 18th of October. Reactor Physics Section has played a key role in this event by carrying out the first approach to criticality with fuel loading in a safe manner and conducting some low power reactor physics experiments which are discussed. The studies made in the field reactor safety and shielding are also connected mainly with the FBTR problems in addition to some work on the PFBR (Prototype Fast Breeder Reactor) detailed design of which has been just started. Studies pertaining to the other two Co-ordinated Research Programmes (CRP) under IAEA contract, namely (1) on the comparative assessment of processing techniques for the analysis of sodium boiling noise detection and, (2) on the contribution of advanced reactors to energy supply have been continued during this year. At the end of this report, a list of publications made by the members of the section and also the sectional seminars held during this period is included. (author)

  14. ACUTE EFFECTS OF THREE DIFFERENT CIRCUIT WEIGHT TRAINING PROTOCOLS ON BLOOD LACTATE, HEART RATE, AND RATING OF PERCEIVED EXERTION IN RECREATIONALLY ACTIVE WOMEN

    Brook L. Skidmore

    2012-12-01

    Full Text Available Interval and circuit weight training are popular training methods for maximizing time-efficiency, and are purported to deliver greater physiological benefits faster than traditional training methods. Adding interval training into a circuit weight-training workout may further enhance the benefits of circuit weight training by placing increased demands upon the cardiovascular system. Our purpose was to compare acute effects of three circuit weight training protocols 1 traditional circuit weight training, 2 aerobic circuit weight training, and 3 combined circuit weight-interval training on blood lactate (BLA, heart rate (HR, and ratings of perceived exertion (RPE. Eleven recreationally active women completed 7 exercise sessions. Session 1 included measurements of height, weight, estimated VO2max, and 13 repetition maximum (RM testing of the weight exercises. Sessions 2-4 were held on non-consecutive days for familiarization with traditional circuit weight training (TRAD, aerobic circuit weight training (ACWT, and combined circuit weight-interval training (CWIT protocols. In sessions 5-7, TRAD, ACWT, and CWIT were performed in a randomized order > 72 hr apart for measures of BLA, HR, and RPE at pre-exercise and following each of three mini-circuit weight training stations. Repeated-measures ANOVAs yielded significant interactions (p < 0.05 in BLA, HR, and RPE. Combined circuit weight- interval training (CWIT produced higher BLA (7.31 ± 0.37 vs. TRAD: 3.99 ± 0.26, ACWT: 4.54 ± 0.31 mmol.L-1, HR (83.51 ± 1.18 vs. TRAD: 70.42 ± 1.67, ACWT: 74.13 ± 1.43 beats.min-1 and RPE (8.14 ± 0.41 vs. TRAD: 5.06 ± 0.43, ACWT: 6.15 ± 0.42 at all measures. Aerobic circuit weight training (ACWT elicited greater RPE than traditional circuit weight training (TRAD at all measures. Including combined circuit weight-interval training (CWIT workouts into exercise programming may enhance fitness benefits and maximize time-efficiency more so than traditional circuit

  15. Pedometer-determined physical activity and active transport in girls

    Schofield Grant

    2008-01-01

    Full Text Available Abstract Background It is well established that the risk of insufficient physical activity is greater in girls than in boys, especially during the adolescent years. The promotion of active transport (AT to and from school has been posited as a practical and convenient solution for increasing girls' total daily activity. However, there is limited information describing the associations between AT choices and girls' physical activity across a range of age, ethnic, and socioeconomic groups. The objectives of this study were to (1 investigate physical activity patterns in a large multiethnic sample of female children and adolescents, and to (2 estimate the physical activity associated with AT to and from school. Methods A total of 1,513 girls aged 5–16 years wore sealed multiday memory (MDM pedometers for three weekdays and two weekend days. The ethnic composition of this sample was 637 European (42.1%, 272 Pacific Island (18.0%, 207 East Asian (13.7%, 179 Maori (11.8%, 142 South Asian (9.4%, and 76 from other ethnic groups (5%. Pedometer compliance and school-related AT were assessed by questionnaire. Results Mean weekday step counts (12,597 ± 3,630 were higher and less variable than mean weekend steps (9,528 ± 4,407. A consistent decline in daily step counts was observed with age: after adjustment for ethnicity and SES, girls in school years 9–10 achieved 2,469 (weekday and 4,011 (weekend fewer steps than girls in years 1–2. Daily step counts also varied by ethnicity, with Maori girls the most active and South Asian girls the least active. Overall, 44.9% of participants used AT for school-related travel. Girls who used AT to and from school averaged 1,052 more weekday steps than those who did not use AT. However, the increases in steps associated with AT were significant only in older girls (school years 5–10 and in those of Maori or European descent. Conclusion Our data suggest that adolescent-aged girls and girls of Asian descent are

  16. Guanylate-Binding Protein 1, an Interferon-Induced GTPase, Exerts an Antiviral Activity against Classical Swine Fever Virus Depending on Its GTPase Activity

    Li, Lian-Feng; Yu, Jiahui; Li, Yongfeng; Wang, Jinghan; Li, Su; Zhang, Lingkai; Xia, Shui-Li; Yang, Qian; Wang, Xiao; Yu, Shaoxiong; Luo, Yuzi; Sun, Yuan; Zhu, Yan; Munir, Muhammad

    2016-01-01

    ABSTRACT Many viruses trigger the type I interferon (IFN) pathway upon infection, resulting in the transcription of hundreds of interferon-stimulated genes (ISGs), which define the antiviral state of the host. Classical swine fever virus (CSFV) is the causative agent of classical swine fever (CSF), a highly contagious viral disease endangering the pig industry in many countries. However, anti-CSFV ISGs are poorly documented. Here we screened 20 ISGs that are commonly induced by type I IFNs against CSFV in lentivirus-delivered cell lines, resulting in the identification of guanylate-binding protein 1 (GBP1) as a potent anti-CSFV ISG. We observed that overexpression of GBP1, an IFN-induced GTPase, remarkably suppressed CSFV replication, whereas knockdown of endogenous GBP1 expression by small interfering RNAs significantly promoted CSFV growth. Furthermore, we demonstrated that GBP1 acted mainly on the early phase of CSFV replication and inhibited the translation efficiency of the internal ribosome entry site of CSFV. In addition, we found that GBP1 was upregulated at the transcriptional level in CSFV-infected PK-15 cells and in various organs of CSFV-infected pigs. Coimmunoprecipitation and glutathione S-transferase (GST) pulldown assays revealed that GBP1 interacted with the NS5A protein of CSFV, and this interaction was mapped in the N-terminal globular GTPase domain of GBP1. Interestingly, the K51 of GBP1, which is crucial for its GTPase activity, was essential for the inhibition of CSFV replication. We showed further that the NS5A-GBP1 interaction inhibited GTPase activity, which was critical for its antiviral effect. Taking our findings together, GBP1 is an anti-CSFV ISG whose action depends on its GTPase activity. IMPORTANCE Classical swine fever virus (CSFV) is the causative agent of classical swine fever (CSF), an economically important viral disease affecting the pig industry in many countries. To date, only a few host restriction factors against CSFV

  17. Barriers to Physical Activity Among Gay Men.

    Cary, Miranda A; Brittain, Danielle R; Dinger, Mary K; Ford, Melissa L; Cain, Meagan; Sharp, Teresa A

    2016-09-01

    Gay men may not be physically active at recommended levels to achieve health benefits. Thus, a need exists to identify general (i.e., common across populations) and population-specific barriers that hinder or stop gay men from participating in physical activity (PA). Salient barriers may be identified through the extent each barrier limits PA (i.e., barrier limitation) and the level of one's confidence to overcome barriers and engage in PA (i.e., self-regulatory efficacy). The purposes of this study were to (1) provide a description of general and population-specific barriers to PA among sufficiently and insufficiently active gay men, (2) identify barrier limitation and self-regulatory efficacy for the reported barriers, and (3) examine the associations between meeting the current PA recommendation, barrier limitation, and self-regulatory efficacy. Participants were 108 self-identified gay males aged 21 to 64 years who completed a web-based survey. A total of 35 general barriers and no population-specific barriers were identified by the sufficiently and insufficiently active groups. The sufficiently active group reported higher self-regulatory efficacy and lower barrier limitation for nearly all reported barriers. A binary logistic regression used to examine the associations between PA, barrier limitation, and self-regulatory efficacy was statistically significant, χ(2)(2, N = 108) = 19.26, p < .0001, R(2) = .16. Only barrier limitation significantly contributed to the model. Future research should continue to examine barriers to PA among gay men to determine whether an intervention needs to be designed specifically for gay men or whether a one-size-fits-all intervention would be effective in helping all men overcome common barriers to engaging in PA. PMID:25643585

  18. Sport and physical activity for mental health

    Carless, David

    2010-01-01

    With approximately 1 in 6 adults likely to experience a significant mental health problem at any one time (Office for National Statistics), research into effective interventions has never been more important. During the past decade there has been an increasing interest in the role that sport and physical activity can play in the treatment of mental health problems, and in mental health promotion. The benefits resulting from physiological changes during exercise are well documented, including improvement in mood and control of anxiety and depression. Research also suggests that socio-cultural a

  19. [Exercise and Physical Activity for Dementia Prevention].

    Shimada, Hiroyuki; Makizako, Hyuma; Doi, Takehiko

    2016-07-01

    The effects of exercise and physical activity on cognitive function and brain health have been established by longitudinal and intervention studies. However, it is not clear whether exercise has positive effects on cognitive function in older adults with mild cognitive impairment. Further studies, including a ramdomized controlled trial with a larger sample size, are required to identify the effects of exercise and multicomponent intervention on cognitive function in the older adults with mild cognitive impairment. It is also important to identify the adequate duration, frequency, and intensity of exercise intervention that is most effective for older individuals. PMID:27395464

  20. The novel trisubstituted pyran derivative D-142 has triple monoamine reuptake inhibitory activity and exerts potent antidepressant-like activity in rodents

    Dutta, Aloke K.; Gopishetty, Bhaskar; Gogoi, Sanjib; Ali, Solav; Zhen, Juan; Reith, Maarten

    2011-01-01

    Major depression disorder is a significant health problem with 10-20% of all adults suffering from this disease. The underlying causes of depression are still unclear and 15% of depressed patients are resistant to all known therapies. Monoamine therapies have so far been the most successful approach for treating depression. Triple monoamine reuptake inhibitors have recently been implicated in generation of potent antidepressant activity while possibly exhibiting a low side-effect profile in a...

  1. Promoting Physical Activity in Primary Care: Overcoming the barriers

    Singer, Joel; Lindsay, Elizabeth A.; Wilson, Douglas M.C.

    1991-01-01

    The principle barriers preventing health care professionals from promoting physical activity include an incomplete understanding of the evidence linking physical activity and health, difficulty in translating research findings into a feasible and efficacious clinical intervention, resistance to adopting a preventive orientation, and concerns about the risks of physical activity. Low level activities likely provide benefit with little risk.

  2. Accumulation of disparity in physical activity in old age

    Eronen, Johanna; von Bonsdorff, Mikaela; Rantakokko, Merja; Rantanen, Taina

    2012-01-01

    Background and aims: The level of physical activity often declines in old age, although many older people would like to be more active than what they are capable of. This leads to unmet physical activity need, the feeling that one’s level of physical activity is inadequate, which is a manifestation of disparity in physical activity in old age. The accumulation of risk factors, including mobility limitations, low socioeconomic status (SES) and lack of social support may increase disparity in p...

  3. Phosphodiesterase-5 activity exerts a coronary vasoconstrictor influence in awake swine that is mediated in part via an increase in endothelin production

    Zhou, Zhichao; de Beer, Vincent J.; Bender, Shawn B.; Jan Danser, A. H.; Merkus, Daphne; Laughlin, M. Harold; Duncker, Dirk J

    2014-01-01

    Nitric oxide (NO)-induced coronary vasodilation is mediated through production of cyclic guanosine monophosphate (cGMP) and through inhibition of the endothelin-1 (ET) system. We previously demonstrated that phosphodiesterase-5 (PDE5)-mediated cGMP breakdown and ET each exert a vasoconstrictor influence on coronary resistance vessels. However, little is known about the integrated control of coronary resistance vessel tone by these two vasoconstrictor mechanisms. In the present study, we inves...

  4. Physical activity patterns, aerobic fitness and body composition in Norwegian children and adolescents : The Physical Activity among Norwegian Children Study

    Kolle, Elin

    2009-01-01

    Regular physical activity is important for children and adolescent’s healthy growth and for their physical, social and mental health. Therefore, comprehensive knowledge is needed on levels and patterns of physical activity, as well as factors influencing physical activity participation. PURPOSE: The overall purpose was to increase the knowledge regarding 9- and 15-year-olds physical activity level, aerobic fitness and their body composition. Further, to gain increased insight w...

  5. The Effects of Exergaming on Physical Activity in a Third-Grade Physical Education Class

    Shayne, Rachel K.; Fogel, Victoria A.; Miltenberger, Raymond G.; Koehler, Shannon

    2012-01-01

    We compared the effects of exergaming and traditional physical education on physical activity among 4 active children who were not overweight and who had experience with the exergaming activities prior to the study. Results showed that exergaming produced substantially higher percentages of physical activity and opportunity to engage in physical…

  6. Physical activity in spondyloarthritis: a systematic review

    O’Dwyer, Tom

    2014-10-01

    Physical activity (PA) is associated with numerous health-related benefits among adults with chronic diseases and the general population. As the benefits are dose-dependent, this review aims to establish the PA levels of adults with spondyloarthritis and to compare these to the general population. Electronic databases (Cochrane Central Register of Controlled Trials, EMBASE, MEDLINE\\/PubMed, PEDro, AMED, CINAHL) were systematically searched from inception to May 2014 using medical subject headings and keywords. This was supplemented by searching conference abstracts and hand-searching reference lists of included studies. Eligible studies were randomized controlled trials and observational studies of adults with SpA in which free-living PA or energy expenditure levels were measured. Subjects less than 18 years or with juvenile-onset SpA were excluded. Outcomes included objective and self-report measurements. Two reviewers independently screened studies for inclusion and assessed methodological quality using the Cochrane risk of bias tool and the RTI item bank. From the 2,431 records reviewed, nine studies involving 2,972 participants were included. This review focused on qualitative synthesis. Meta-analyses were not undertaken due to differences in study design, measurement tools, and participant characteristics. This heterogeneity, coupled with the risk of bias inherent in the included observational studies, limits the generalizability of findings. Objective measurements suggest PA levels may be lower among adults with spondyloarthritis than in healthy population controls. Self-reported PA and self-reported rates of adherence to PA recommendations varied largely across studies; higher disease activity was associated with lower self-reported PA levels. Physical activity levels may be lower in adults with axial spondyloarthritis, with higher disease activity associated with lower PA levels.

  7. BOOK REVIEW: Physics of Space Plasma Activity

    Cramer, N. F.

    2007-11-01

    This book provides a timely review of our present understanding of plasma phenomena in magnetized terrestrial and solar space plasmas. The author's emphasis is on the fluid and particle modeling and interpretation of observed active processes in space plasmas, i.e. `the physical background of large plasma eruptions in space'. It is somewhat alarming for a plasma physicist to read that an emphasis on processes in spatially inhomogeneous plasmas means that the work `... excludes a considerable fraction of the available methods in space plasma physics, such as the theory of waves, instabilities and wave particle interactions on a homogeneous background', particularly in light of the fact that much of our knowledge of these plasmas is derived from observations of such waves. However, it is clear on reading the book that such a restriction is not a disadvantage, but allows the author to concentrate on the main theme of the book, namely the use of fluid and particle pictures to model the equilibrium and active states of space plasmas. There are many other books which cover the wave aspects of space plasmas, and would complement this book. The book's coverage is based on the extensive and profound research of the author and his colleagues in the area of fluid and particle modeling of space plasma structures. After an introduction to the physical setting of active plasmas, and a necessarily concise, but effective, discussion of the fluid and particle models to be used, the steady states of the magnetized plasmas of interest are treated, including the magnetosphere, solar plasmas and current sheets. Next the dynamics of unstable states is covered, including MHD and tearing instabilities, and nonlinear aspects, with a detailed discussion of magnetic reconnection. Finally, the models are applied to magnetospheric and solar observations. The book is attractively written and produced, and this reviewer managed to find a minimum number of errors. A particularly attractive

  8. Relationship between physical functioning and physical activity in the lifestyle interventions and independence for elders pilot

    OBJECTIVES: To determine whether participation in usual moderate-intensity or more-vigorous physical activity (MVPA) is associated with physical function performance and to identify sociodemographic, psychosocial, and disease-related covariates that may also compromise physical function performance....

  9. Study on the physical activity level of Turkish males

    Ramiz Arabacı

    2008-12-01

    Full Text Available The aim of this study was to investigate physical activity (PA level of the Turkish males who lived in BUrsa. A total of 365 subjects between 18 - 69 age participated to this study. To determine physical activity levels, International Physical Activity Questionnaire (IPAQ was applied. PA levels of subjects were categorized as inactive, minimum active and HEPA active by using MET method. The relations of parameters, such as their age, BMI, education, marital status, number of children, smoking and alcohol use were determined with PA level. The results were analyzed by using Chi - Square test. The participants have 1725 METmin/week average physical activity level, and 47.7 % of them were physically inactive, 30.4 % were physically minimum active and 21.9 % were physically hepa active. As a result, it can be said that the physical activity levels of Turkish males who lived in Bursa are not sufficient and the inactive people are very common.

  10. International Centre for Theoretical Physics. Scientific activities in 1985

    A review of the scientific activities of the Centre, including workshops, research, and training-for-research is presented. The scientific program consists of ten main fields, Physics and Energy, Fundamental Physics, Physics of Condensed Matter, Applied Physics, Physics of the Living State, Physics of the Environment, Mathematics, Physics Teaching, Experimental Physics Training, and Physics and Development. In addition to a brief description of each workshop, symposium, college, and meeting, tables summarizing the participation at ICTP activities are given. A list of preprints and internal reports issued in 1985 is included

  11. International Centre for Theoretical Physics, Trieste. Scientific activities in 1990

    The document contains three parts: Part I is a general review of the scientific activities of the Centre in 1990, including a statistical digest. Part II describes the scientific programme of the Centre in the following fields: Fundamental physics, condensed nuclear physics, mathematics, physics and energy, physics and environment, physics of the living state, applied physics Adriatico research conferences and other aspects of the Centre activities. Part III lists the publications issued in 1990

  12. International Centre for Theoretical Physics: scientific activities in 1984

    A review of the scientific activities of the Centre, including workshops, research, and training-for-research is presented. The scientific program consists of seven main fields, Physics and Energy, Fundamental Physics, Physics and Technology, Physics of the Living State, Physics of the Environment, Physics and Development, and Mathematics. In addition to a brief description of each workshop, symposium, college, and meeting, tables summarizing the participation at ICTP activities are given. A list of preprints and internal reports issued in 1984 is included

  13. International Centre for Theoretical Physics, Trieste: Scientific activities in 1989

    The document contains three parts. Part I is a general review of the scientific activities in 1989 including a statistical digest. Part II describes the scientific programme in Fundamental Physics, Condensed Matter Physics, Mathematics, Physics and Energy, Physics and Environment, Applied Physics, Physics of the Space, Adriatico Research Conferences and other aspects of the Centre activities. Part III lists the publications issued in 1989. Tabs

  14. Predicting Child Physical Activity and Screen Time: Parental Support for Physical Activity and General Parenting Styles

    Langer, Shelby L; Crain, A. Lauren; Senso, Meghan M.; Levy, Rona L.; Sherwood, Nancy E

    2014-01-01

    Objective: To examine relationships between parenting styles and practices and child moderate-to-vigorous physical activity (MVPA) and screen time. Methods: Participants were children (6.9 ± 1.8 years) with a body mass index in the 70–95th percentile and their parents (421 dyads). Parent-completed questionnaires assessed parental support for child physical activity (PA), parenting styles and child screen time. Children wore accelerometers to assess MVPA. Results: Parenting style did not predi...

  15. Cardiovascular risk profile: Cross-sectional analysis of motivational determinants, physical fitness and physical activity

    Kiers Henri

    2010-10-01

    Full Text Available Abstract Background Cardiovascular risk factors are associated with physical fitness and, to a lesser extent, physical activity. Lifestyle interventions directed at enhancing physical fitness in order to decrease the risk of cardiovascular diseases should be extended. To enable the development of effective lifestyle interventions for people with cardiovascular risk factors, we investigated motivational, social-cognitive determinants derived from the Theory of Planned Behavior (TPB and other relevant social psychological theories, next to physical activity and physical fitness. Methods In the cross-sectional Utrecht Police Lifestyle Intervention Fitness and Training (UP-LIFT study, 1298 employees (aged 18 to 62 were asked to complete online questionnaires regarding social-cognitive variables and physical activity. Cardiovascular risk factors and physical fitness (peak VO2 were measured. Results For people with one or more cardiovascular risk factors (78.7% of the total population, social-cognitive variables accounted for 39% (p In addition to the prediction of intention to engage in physical activity and physical active behavior, we explored the impact of the intensity of physical activity. The intentsity of physical activity was only significantly related to physical active behavior (beta = .253, p 2 = .06, p 2 = .23, p For people with one or more cardiovascular risk factors, 39.9% had positive intentions to engage in physical activity and were also physically active, and 10.5% had a low intentions but were physically active. 37.7% had low intentions and were physically inactive, and about 11.9% had high intentions but were physically inactive. Conclusions This study contributes to our ability to optimize cardiovascular risk profiles by demonstrating an important association between physical fitness and social-cognitive variables. Physical fitness can be predicted by physical active behavior as well as by self-efficacy and the intensity of

  16. Youth perceptions of how neighborhood physical environment and peers affect physical activity: a focus group study

    Smith, Alan L.; Troped, Philip J; McDonough, Meghan H; DeFreese, J.D.

    2015-01-01

    Objective There is need for a youth-informed conceptualization of how environmental and social neighborhood contexts influence physical activity. We assessed youths’ perceptions of their neighborhood physical and peer environments as affecting physical activity. Methods Thirty-three students (20 girls; ages 12-14 years) participated in focus groups about the physical environment and peers within their neighborhoods, and their understanding of how they affect physical activity. Results Inducti...

  17. Becoming the Physical Activity Champion: Empowerment through Social Marketing

    Colquitt, Gavin; Alfonso, Moya L.; Walker, Ashley

    2014-01-01

    Physical education teachers can champion their profession through marketing the importance of physical activity to children and families in the communities they serve. Social marketing, a consumer-based approach to behavior change, is an excellent choice for physical education teachers who want to "sell" physical activity to their…

  18. Applied nuclear physics group - activities report. 1977-1997

    This report presents the activities conducted by the Applied Nuclear Physics group of the Londrina State University - Applied Nuclear Physics Laboratory - Brazil, from the activities beginning (1977) up to the end of the year 1997

  19. What I Need to Know about Physical Activity and Diabetes

    ... PDF, 293 KB). Alternate Language URL Español What I need to know about Physical Activity and Diabetes ... the words in bold type. [ Top ] What should I do before I start a physical activity program? ...

  20. Physical Activity and Alzheimer's-Related Hippocampal Atrophy

    ... Plan National Alzheimer's Project Act (NAPA) About ADEAR Physical activity and Alzheimer’s-related hippocampal atrophy August 4, 2014 Physical activity may help prevent atrophy of the hippocampus, a ...

  1. International Centre for Theoretical Physics: scientific activities in 1982

    Research and training-for-research were carried out in the following areas: physics and energy (nuclear physics, solar energy), physics and frontiers of knowledge (elementary particles and fundamental theory), physics of the living state, physics and technology (condensed matter physics), applicable mathematics and planning models (applicable mathematics, mathematical ecology), physics of the environment and of natural resources (geomagnetism, ionospheric and magnetospheric physics, atmospheric physics), and physics and development. Activities included both research at the Centre and a number of workshops and symposia. The subjects treated are briefly summarized, and references to preprints and internal reports are given

  2. Health enhancing physical activity, sociodemographic factors and the neighbourhood environment

    Bergman, Patrick

    2009-01-01

    BACKGROUND: A physically active lifestyle is beneficial for good health. Despite this, it seems that many people are not sufficiently active. Attempts to promote the population levels of physical activity have not been successful. This has led researchers to find new ways to tackle the problem. Ecological models place more emphasis on the physical environment s potential influence on physical activity behaviour than other behavioural models do, but a greater understanding of...

  3. ATTITUDES TOWARD PHYSICAL ACTIVITY AND SPORT

    José Alfredo Balderrama-Ruedas

    2014-07-01

    Full Text Available One of the main problems of this country is currently sedentary carrying Mexicans, top level global envelope weight and obesity, as well as problems of prosocial behavior and crime, adding the poor academic performance in the education sector, this research seeks to know the attitudes of students toward physical activation and sport within their training and performance as future teachers.This research was conducted under the qualitative approach, using the ethnographic method, using observation technique, and the journal of field and survey instruments collection, to interpret the data obtained to the results applied to the seven phases of María Mercedes Gagneten (1999.Within the conclusions one can mention the change of attitude by the students towards this type of activities, from negative attitudes to positive, detected the soccer, volleyball and basketball as the most widely practised sports by students as well as swimming as one of the most reputable. We analysed what could be the possible causes by which students not carried out these activities, the lack of information, culture and aspects of the internal organisation of the Student Council as direct factors.

  4. Effect of physical activity counseling on physical activity of older people in Finland (ISRCTN 07330512).

    Rasinaho, Minna; Hirvensalo, Mirja; Törmäkangas, Timo; Leinonen, Raija; Lintunen, Taru; Rantanen, Taina

    2012-12-01

    The aim of this study was to describe the underlying theory and the implementation of a 2-year individualized physical activity counseling intervention and to evaluate whether benefits persisted 1.5 years after the intervention. The sample included 632 sedentary 75- to 81-year-old participants. Data were collected in 2003-2005. The participants were randomly assigned to an intervention group and a control group. The intervention consisted of an individualized face-to-face meeting followed by telephone contacts every 4 months for 2 years, with the aim to increase participation in specific physical activities as well as to increase habitual physical activity. At the 2-year follow-up, the prevalence of physical activities in the intervention group vs. control group was as follows: supervised calisthenics training 20 vs. 16%, walking for fitness 69 vs. 62%, weight training 13 vs. 8% and water aerobics 19 vs. 7%. For water aerobics and walking for fitness, the treatment effect was significant [water aerobics odds ratio (OR) 2.49, 95% confidence interval (CI) 1.16-5.36, walking for fitness OR 1.58, 95% CI 1.05-2.40]. As to the other activities, the effect did not reach statistical significance. At the 1.5-year post-intervention, the follow-up results indicated that the intervention effect was still evident. The subgroup analyses suggested that physical activity counseling may be most efficacious among people with intact mobility, while those having manifest mobility limitations may not benefit from it. Older people who have manifest mobility limitations may need more face-to-face counseling. PMID:21911336

  5. Focus on Freshman: Basic Instruction Programs Enhancing Physical Activity

    Curry, Jarred; Jenkins, Jayne M.; Weatherford, Jennifer

    2015-01-01

    Physical activity sharply decreases after different life stages, particularly high school graduation to beginning university education. The purpose of this study was to investigate the effect of a specifically designed university physical activity class, Exercise Planning for Freshman (EPF), on students' physical activity and group cohesion…

  6. Striding Toward Social Justice: The Ecologic Milieu of Physical Activity

    Lee, Rebecca E.; Cubbin, Catherine

    2009-01-01

    Disparities in physical activity should be investigated in light of social justice principles. This manuscript critically evaluates evidence and trends in disparities research within an ecologic framework, focusing on multi-level factors such as neighborhood and racial discrimination that influence physical activity. Discussion focuses on strategies for integrating social justice into physical activity promotion and intervention programming within an ecologic framework.

  7. Physical Activity and Youth with Disabilities: Barriers and Supports

    Block, Martin E.; Taliaferro, Andrea; Moran, Tom

    2013-01-01

    Physical activity and active use of leisure time is important for everyone but particularly important for youth with disabilities. Unfortunately, youth with disabilities often have a difficult time or are even excluded from participating in physical activity due to limited physical and cognitive skills, attitudinal barriers in the community, lack…

  8. Sport, physical activity and social exclusion.

    Collins, Mike

    2004-08-01

    This paper is a brief review of the concept of social exclusion and its evolution. I address which individuals are excluded from sport and physical activity and how; link inclusion policies to the 'cross-cutting issues' and the idea of social capital; and outline the intervention policies being adopted in the new sport strategy 'Game Plan' (). I address the link between transport, exercise and health in a case study. Since these policies are new, research and evaluation has been short term and scattered, and outcome measurements have not yet received academic or professional consensus, it is too soon to say for sure what works or even to confirm what is best practice. PMID:15370484

  9. Promoting Children's Physical Activity in Physical Education: The Role of Active Video Gaming

    Zhang, Tao; Moore, William; Gu, Xiangli; Chu, Tsz Lun; Gao, Zan

    2016-01-01

    Approximately half of the children in the United States do not meet the global physical activity guidelines, and many children adopt sedentary lifestyles. Given the fact about two-thirds children are classified as overweight or obese, traditional video games have been blamed as a major contributor to children's sedentary behavior and excessive…

  10. Physical activity and physical activity induced energy expenditure in humans: measurement, determinants and effects

    KlaasRWesterterp

    2013-04-01

    Full Text Available Physical activity is defined as any bodily movement produced by skeletal muscles that results in energy expenditure. The doubly labelled water method for the measurement of total energy expenditure, in combination with resting energy expenditure, is the reference for physical activity under free-living conditions. To compare the physical activity level (PAL within and between species, total energy expenditure is divided by resting energy expenditure resulting in a figure without dimension. The PAL for sustainable lifestyles ranges between a minimum of 1.1-1.2 and a maximum of 2.0-2.5. The average PAL increases from 1.4 at age 1 year to 1.7-1.8 at reproductive age and declines again to 1.4 at age 90 year. Exercise training increases PAL in young adults when energy balance is maintained by increasing energy intake. Professional endurance athletes can reach PAL values around 4.0. Most of the variation in PAL between subjects can be ascribed to predisposition. A higher weight implicates higher movement costs and less body movement but not necessarily a lower PAL. Changes in physical activity primarily affect body composition and to a lesser extent body weight. Modern man has a similar PAL as a wild mammal of a similar body size.

  11. Physical Fitness and Physical Activity in Adolescents with Asperger Syndrome: A Comparative Study

    Borremans, Erwin; Rintala, Pauli; McCubbin, Jeffrey A.

    2010-01-01

    While physical activity is beneficial for youth with developmental disabilities, little is known about those individuals' fitness profile and levels of activity. Therefore the purpose of this study was to investigate the physical fitness profile and physical activity level of 30 adolescents with and without Asperger syndrome (AS). Evaluations were…

  12. LEISURE-TIME PHYSICAL ACTIVITY IN LATE ADOLESCENCE: A Cohort Study of Stability, Correlates and Familial Aggregation in Twin Boys and Girls

    Marja Aarnio

    2003-01-01

    Regular exercise has been shown to exert many positive effects on health. Sedentary behaviour often originates in childhood and many common adult chronic diseases are related to inactivity. Adolescent physical activity patterns and health habits are important subjects to study because of the known associations of physical activity with other health habits and the evidence that these associations track into adulthood. The data for this study were gathered as a part of FinnTwin16, a longitudi...

  13. Chitosan nanoparticles loaded with the antimicrobial peptide temporin B exert a long-term antibacterial activity in vitro against clinical isolates of Staphylococcus epidermidis

    Anna Maria Piras

    2015-04-01

    Full Text Available Nowadays, the alarming rise in multidrug-resistant microorganisms urgently demands for suitable alternatives to current antibiotics. In this regard, antimicrobial peptides (AMPs have received growing interest due to their broad spectrum of activities, potent antimicrobial properties, unique mechanisms of action and low tendency to induce resistance. However, their pharmaceutical development is hampered by potential toxicity, relatively low stability and manufacturing costs. In the present study, we tested the hypothesis that the encapsulation of the frog-skin derived AMP temporin B (TB into chitosan nanoparticles (CS-NPs could increase peptide’s antibacterial activity, while reducing its toxic potential. TB-loaded CS-NPs with good dimensional features were prepared, based on the ionotropic gelation between CS and sodium tripolyphosphate. The encapsulation efficiency of TB in the formulation was up to 75%. Release kinetic studies highlighted a linear release of the peptide from the nanocarrier, in the adopted experimental conditions. Interestingly, the encapsulation of TB in CS-NPs demonstrated to reduce significantly the peptide’s cytotoxicity against mammalian cells. Additionally, the nanocarrier evidenced a sustained antibacterial action against various strains of Staphylococcus epidermidis for at least 4 days, with up to 4-log reduction in the number of viable bacteria compared to plain CS-NPs at the end of the observational period. Of note, the antimicrobial evaluation tests demonstrated that while the intrinsic antimicrobial activity of CS ensured a burst effect, the gradual release of TB further reduced the viable bacterial count, preventing the regrowth of the residual cells and ensuring a long-lasting antibacterial effect. The developed nanocarrier is eligible for the administration of several AMPs of therapeutic interest with physical-chemical characteristics analogue to those of TB.

  14. Experiences of physical activity during pregnancy in Danish nulliparous women with a physically active life before pregnancy. A qualitative study

    Hegaard, Hanne Kristine; Kjaergaard, Hanne; Damm, Peter P; Petersson, Kerstin; Dykes, Anna-Karin

    2010-01-01

    National guidelines recommend that healthy pregnant women take 30 minutes or more of moderate exercise a day. Most women reduce the level of physical activity during pregnancy but only a few studies of women's experiences of physical activity during pregnancy exist. The aim of the present study was...... to elucidate experiences and views of leisure time physical activity during pregnancy in nulliparous women who were physically active prior to their pregnancy....

  15. Objective and perceived availability of physical activity opportunities: Differences in associations with physical activity behavior among urban adolescents

    van der Horst Klazine; Oenema Anke; Prins Richard G; Brug Johannes

    2009-01-01

    Abstract Background This study examined the associations of the perceived and objective environment with adolescent engagement in sports activities and walking and cycling in leisure time. It also explored the degree of agreement between objective and perceived availability of physical activity (PA) facilities in neighborhoods. Methods Cross-sectional data on physical activity, the perceived availability of physical activity opportunities (perceived physical environment) was assessed through ...

  16. International Centre for Theoretical Physics, Trieste Scientific activities in 1991

    The document contains three parts. Part 1 is a general review of the scientific activities of the Centre in 1991, including a statistical digest. Part II presents the scientific programme of the Centre in the following fields: Fundamental Physics, Condensed Matter Physics, Mathematics, Physics and Energy, Physics and Environment, Applied Physics, Adriatico Research Conferences, as well as other aspects of the Centre activities in 1991. Part III lists the publications issued in 1991. Tabs

  17. Physical Activity Stories: Assessing the "Meaning Standard" in Physical Education

    Johnson, Tyler G.

    2016-01-01

    The presence of the "meaning standard" in both national and state content standards suggests that professionals consider it an important outcome of a quality physical education program. However, only 10 percent of states require an assessment to examine whether students achieve this standard. The purpose of this article is to introduce…

  18. BC Walks: Replication of a Communitywide Physical Activity Campaign.

    Reger-Nash, Bill; Fell, Patricia; Spicer, Deborah; Fisher, Brian D.; Cooper, Linda; Chey, Tien; Bauman, Adrian

    2006-01-01

    Introduction Individuals not engaging in recommended amounts of moderate-intensity physical activity are deemed insufficiently active and are at greater risk of chronic disease. Social marketing strategies may promote positive changes in physical activity levels among insufficiently active individuals. Methods A quasi-experimental design was used to determine whether the results of a previous communitywide physical activity social marketing campaign conducted in Wheeling, WVa (population, 31,...

  19. The improved physical activity index for measuring physical activity in EPIC Germany.

    Angelika Wientzek

    Full Text Available In the European Investigation into Cancer and Nutrition study (EPIC, physical activity (PA has been indexed as a cross-tabulation between PA at work and recreational activity. As the proportion of non-working participants increases, other categorization strategies are needed. Therefore, our aim was to develop a valid PA index for this population, which will also be able to express PA continuously. In the German EPIC centers Potsdam and Heidelberg, a clustered sample of 3,766 participants was re-invited to the study center. 1,615 participants agreed to participate and 1,344 participants were finally included in this study. PA was measured by questionnaires on defined activities and a 7-day combined heart rate and acceleration sensor. In a training sample of 433 participants, the Improved Physical Activity Index (IPAI was developed. Its performance was evaluated in a validation sample of 911 participants and compared with the Cambridge Index and the Total PA Index. The IPAI consists of items covering five areas including PA at work, sport, cycling, television viewing, and computer use. The correlations of the IPAI with accelerometer counts in the training and validation sample ranged r = 0.40-0.43 and with physical activity energy expenditure (PAEE r = 0.33-0.40 and were higher than for the Cambridge Index and the Total PA Index previously applied in EPIC. In non-working participants the IPAI showed higher correlations than the Cambridge Index and the Total PA Index, with r = 0.34 for accelerometer counts and r = 0.29 for PAEE. In conclusion, we developed a valid physical activity index which is able to express PA continuously as well as to categorize participants according to their PA level. In populations with increasing rates of non-working people the performance of the IPAI is better than the established indices used in EPIC.

  20. Low-molecular-weight fractions of Alcalase hydrolyzed egg ovomucin extract exert anti-inflammatory activity in human dermal fibroblasts through the inhibition of tumor necrosis factor-mediated nuclear factor κB pathway.

    Sun, Xiaohong; Chakrabarti, Subhadeep; Fang, Jun; Yin, Yulong; Wu, Jianping

    2016-07-01

    Ovomucin is a mucin-like protein from egg white with a variety of biological functions. We hypothesized that ovomucin-derived peptides might exert anti-inflammatory activity. The specific objectives were to test the anti-inflammatory activities of different ovomucin hydrolysates and its various fractions in human dermal fibroblasts, and to understand the possible molecular mechanisms. Three ovomucin hydrolysates were prepared and desalted; only the desalted Alcalase hydrolysate showed anti-inflammatory activity. Desalting of ovomucin hydrolysate enriched the proportion of low-molecular-weight (MW) peptides. Indeed, ultrafiltration of this hydrolysate displayed comparable anti-inflammatory activity in dermal fibroblasts, indicating the responsible role of low-MW bioactive peptides in exerting the beneficial biological function. The anti-inflammatory activity of low-MW peptides was regulated through the inhibition of tumor necrosis factor-mediated nuclear factor κ-light-chain-enhancer of activated B cells activity. Our study demonstrated that both peptide composition and MW distribution play important roles in anti-inflammatory activity. The low-MW fractions prepared from ovomucin Alcalase hydrolysate may have potential applications for maintenance of dermal health and treatment of skin diseases. PMID:27333955

  1. Correlates of Physical Activity in Asian Adolescents: A Literature Review

    Husna Hidayati

    2012-08-01

    Full Text Available Background: Physical activity is important to prevent several chronic diseases in adulthood. Nowadays, young people do not regularly perform physical activity. Several factors may influence their decision. Most of studies were conducted in western countries. However the findings might not be generalized regarding the differences in culture and social condition. Therefore, reviewing the correlates of physical activity among adolescents in Asian countries is essential. Purpose: To update the state of knowledge on factors associated with adolescents’ physical activity in Asian countries. Methods: Literature review on existing articles retrieved from electronic databases was conducted. The review on factors of physical activity was set based on the setting of study, adolescents as participants of the study and the year of publication ranged from 2002-2011. Result: The findings compiled the evidence of relationships between physical activity and several influencing factors. Intrapersonal factors age, gender, socioeconomic status, parental education, and perceptions related to physical activity- perceived self efficacy, perceived benefits, and perceived barriers, interpersonal factors (family and peer influences and extra-personal factors (school policy and living arrangement were identified. Self efficacy was manifested as the strongest influencing factor in most studies. This review highlighted the cultural issues on physical activities of adolescents in Asian countries. Conclusion: This paper provided comprehensive knowledge related to factors influencing physical activity in Asian adolescents. The issue of cultural sensitivity should be considered in the future intervention program designed to improve physical activity of adolescents. Keyword: adolescent, physical activity, health Promotion, Asian countries

  2. The Benefits of Natural Environments for Physical Activity.

    Shanahan, Danielle F; Franco, Lara; Lin, Brenda B; Gaston, Kevin J; Fuller, Richard A

    2016-07-01

    Urbanisation has a profound effect on both people and the environment, as levels of physical activity decline and many natural ecosystems become lost or degraded. Here we draw on emerging research to examine the role of green spaces in providing a venue for outdoor physical activity, and in enhancing the benefit of a given amount of physical activity for urban residents. We identify critical knowledge gaps, including (1) whether (and for whom) levels of physical activity increase as new green spaces are introduced or old spaces reinvigorated; (2) which characteristics of nature promote physical activity; (3) the extent to which barriers to outdoor physical activity are environmental or social; and (4) whether the benefits of physical activity and experiences of nature accrue separately or synergistically. A clear understanding of these issues will help guide effective investment in green space provision, ecological enhancement and green exercise promotion. PMID:26886475

  3. International Centre for Theoretical Physics, Trieste. Scientific activities in 1993

    The annual report of the International Centre for Theoretical Physics from Trieste for 1993 contains four parts. Part I gives statistical data on the main activities of the Centre. Part II presents the scientific programme structured as follows: Fundamental physics, Condensed matter physics, Mathematics, Physics and energy, Physics and environment, Physics of the living state, Applied physics, Adriatico Research Conferences, Diploma Course, Laboratories, Long-term visitors, Network of Associate Members and Federal Institutes, Training and research at italian laboratories, External Activities, Science, High Technology and Development Programme, Meeting hosted, Awards. Part III lists the publications issued in 1993. Part IV presents the scientific support services. Tabs

  4. International Centre for Theoretical Physics: Scientific activities in 1986

    A review of the scientific activities of the Centre in 1986, including workshops, research and training-for-research is presented. The scientific program consists of eight main fields: Physics and Energy, Fundamental Physics, Physics of Condensed Matter, Applied Physics, Mathematics, Physics of the Environment and of National Resources, Physics of the Living State, Physics and Development. In addition to a brief description of each workshop, symposium, college and meeting, tables summarizing the participation of ICTP activities are given. A list of preprints and internal reports issued in 1986 is included

  5. The Intricacies of Children’s Physical Activity

    Brusseau Timothy A

    2015-09-01

    Full Text Available Understanding the physical activity patterns of youth is an essential step in preparing programming and interventions needed to change behavior. To date, little is known about the intricacies of youth physical activity across various physical activity segments (i.e. in school, out of school, recess, classroom physical activity, physical education, weekends, etc.. Therefore, the purpose of the study was to examine the physical activity patterns of elementary school children across various segments and during two seasons. A total of 287 fourth and fifth graders from the Southwest US wore the Yamax Digiwalker SW-200 pedometer for 7 consecutive days during the Fall and Spring seasons. Children were prompted to record their step counts when arriving and leaving school, before and after physical education and recess, as well as on the weekends. Means and standard deviations were calculated and ANOVAs and t tests were utilized to examine difference by sex, season, and segment. Youth were more active outside of school and on weekdays (p<0.05. Boys were generally more active than girls and all youth were more active during the milder Spring season. There is a clear need for Comprehensive School Physical Activity Programming and weekend physical activity opportunities. Furthermore, greater emphasis is needed on PE and across other activity segments for girls to increase their physical activity levels.

  6. International Centre for Theoretical Physics, Trieste, scientific activities in 1992

    The document contains three parts. Part I is a programme overview of 1992 including a description of scientific activities and statistics about participation by geographic areas and by activities. Part II presents the scientific programme in the following fields: fundamental physics, condensed matter physics, mathematics, physics related to the energy problems, physics and the environment, physics of the living state (of matter), and applied physics. Conferences and other activities by the centre are also listed. Part III lists the publications issued in 1992. 5 tabs

  7. Physical Activity, Exercise, and Sedentary Behavior in College Students.

    Buckworth, Janet; Nigg, Claudio

    2004-01-01

    The authors examined the relationship between physical activity, exercise, and sedentary behaviors in 493 college students who were enrolled in 10 conditioning activity classes and had completed questionnaires at the beginning of the course. They analyzed sedentary activities and indicators of participation in exercise and physical activity by…

  8. Millikan Lecture 1996: Promoting active learning based on physics education research in introductory physics courses

    Laws, P. W.

    1997-01-01

    Early in his career Robert Millikan experimented with a laboratory-based method of teaching introductory physics that bears close resemblance to Workshop Physics.® In this talk, key elements of Workshop Physics are summarized. Some Workshop Physics activities are described which involve apparati that are used for rapid observations of conceptual aspects of physical phenomena as well as for equation verification experiments. Challenges are discussed that must be faced if recently developed activity-based approaches to teaching based on the outcomes of physics education research are to provide a foundation for a major paradigm shift in physics teaching.

  9. Physical activity and cardiovascular risk factors in children

    Andersen, Lars Bo; Riddoch, Chris; Kriemler, Susi;

    2011-01-01

    A number of recent systematic reviews have resulted in changes in international recommendations for children's participation in physical activity (PA) for health. The World Health Authority (WHO) has recently released new recommendations. The WHO still recommends 60 min of moderate to vigorous...... physical activity (MVPA), but also emphasises that these minutes should be on top of everyday physical activities. Everyday physical activities total around 30 min of MVPA in the quintile of the least active children, which means that the new recommendations constitute more activity in total compared with...

  10. Effects of Vigorous Intensity Physical Activity on Mathematics Test Performance

    Phillips, David S.; Hannon, James C.; Castelli, Darla M.

    2015-01-01

    The effect of an acute bout of physical activity on academic performance in school-based settings is under researched. The purpose of this study was to examine associations between a single, vigorous (70-85%) bout of physical activity completed during physical education on standardized mathematics test performance among 72, eighth grade students…

  11. Physical Activity & Sport for the Secondary School Student. Fifth Edition.

    Dougherty, Neil J., Ed.

    This collection of papers offers a comprehensive text about contemporary physical activities and sports forms. It provides students with an overview of the various physical activities, skill technique required, safety, scoring, rules and etiquette, strategies, equipment, and related terminology. The 26 papers are: (1) "Physical Fitness" (Carolyn…

  12. Top 10 Research Questions Related to Children Physical Activity Motivation

    Chen, Ang

    2013-01-01

    Physical activity is critical to healthy development of children. It is well documented that helping children develop and sustain a physically active lifestyle requires children to become motivated. Many studies have been conducted in the past 2.5 decades on determinants and correlates for children and adolescents' physical activity…

  13. Initiating and Strengthening College and University Instructional Physical Activity Programs

    Sweeney, Michelle M.

    2011-01-01

    The National Association for Sport and Physical Education supports the offering of strong college and university instructional physical activity programs (C/UIPAPs). With a rapid decline in physical activity levels, high stress levels, and unhealthy weight-loss practices among college-age students, it is apparent that C/UIPAPs embedded in the…

  14. Childhood Obesity Prevention and Physical Activity in Schools

    Davidson, Fiona

    2007-01-01

    Purpose: The aim of this literature review is to summarise and synthesise the research base concerning childhood obesity and physical activity, particularly in relation to teachers and schools and within a policy context of the UK. The review investigates childhood obesity, physical activity, physical education, the role of teachers, the role of…

  15. Body mass index and daily physical activity in anorexia nervosa.

    Bouten, C V; van Marken Lichtenbelt, W D; Westerterp, K R

    1996-08-01

    The level of daily physical activity in 11 non-hospitalized women with anorexia (age: 21-48 yr, body mass index (BMI): 12.5-18.3 kg.m-2), compared with 13 normal-weight women (age: 20-35 yr, BMI 19.2-26.7 kg.m-2), was studied in relation to BMI. Daily physical activity over a 7-d period was determined from movement registration and by combining measurements of average daily metabolic rate (measured in a respiration chamber). Group averages of daily physical activity were similar for subjects with anorexia and control subjects. However, women with anorexia had either a low or a high level of daily physical activity, whereas most control subjects had a moderate level of daily physical activity. In the women with anorexia, daily physical activity was significantly related to BMI (r = 0.84). Subjects with a BMI > or = kg.m-2 were equally or more active compared with control subjects, while subjects with a BMI active compared with control subjects. The increased physical activity at BMI > or = 17 kg.m-2 is considered to be facilitated by an improving physical capacity combined with the advantages of a low body mass during weight-bearing activities. At lower BMI, undereating and declining physical capacity may have caused the observed decrease in daily physical activity. PMID:8871905

  16. International Centre for Theoretical Physics, Trieste. Scientific activities in 1994

    This publication gives a comprehensive overview of the scientific activities during 1994 of the International Centre for Theoretical Physics, Trieste. In particular, it gives (i) a summary of these activities accompanied by statistical data (comparison with 1993, participation by geographical area, breakdown by field of activity, activities held at and outside the ICTP, and participation by activity); (ii) an overview of the scientific programme (fundamental physics, condensed matter physics, mathematics, physics and energy, physics and the environment, physics of the living state, applied physics, diploma courses, and other research) while listing long-term visitors, networks of associate members and federal institutes, training and research at Italian laboratories, external activities, science, the high technology and development programme, the books and equipment programme, award; (iii) a list of publications, and (iv) a list of scientific support services

  17. Relationship between physical activity and physical fitness in school-aged children with developmental language disorders

    van der Niet, Anneke G.; Hartman, Esther; Moolenaar, Ben J.; Smith, Joanne; Visscher, Chris

    2014-01-01

    Children with developmental language disorders (DLD) often experience difficulty in understanding and engaging in interactive behavior with other children, which may lead to reduced daily physical activity and fitness levels. The present study evaluated the physical activity and physical fitness lev

  18. Elementary Physical Education Teachers' Content Knowledge of Physical Activity and Health-Related Fitness

    Santiago, Jose A.; Disch, James G.; Morales, Julio

    2012-01-01

    The purpose of this study was to examine elementary physical education teachers' content knowledge of physical activity and health-related fitness. Sixty-four female and 24 male teachers completed the Appropriate Physical Activity and Health-Related Fitness test. Descriptive statistics results indicated that the mean percentage score for the test…

  19. Adolescent Physical Self-Perceptions, Sport/Exercise and Lifestyle Physical Activity

    Gilson, N. D.; Cooke, C. B.; Mahoney, C. A.

    2005-01-01

    Purpose: Domain and sub-domain physical self-perceptions have been associated with adolescent moderate intensity physical activity although the association with different types of adolescent moderate intensity physical activity remains unclear. This study seeks to examine the relationship between personal self-perceptions and adolescent…

  20. Effects of a Physical Education Supportive Curriculum and Technological Devices on Physical Activity

    Clapham, Emily Dean; Sullivan, Eileen C.; Ciccomascolo, Lori E.

    2015-01-01

    The purpose of this study was to examine the effects of a physical education supportive curriculum and technological devices, heart rate monitor (HRM) and pedometer (PED), on physical activity. A single-subject ABAB research design was used to examine amount and level of participation in physical activity among 106 suburban fourth and fifth…

  1. Physical and Psychosocial Factors Associated With Physical Activity in Patients With Chronic Obstructive Pulmonary Disease

    Hartman, Jorine E.; Boezen, H. Marike; de Greef, Mathieu H.; ten Hacken, Nick H.

    2013-01-01

    Objectives: To assess physical activity and sitting time in patients with chronic obstructive pulmonary disease (COPD) and to investigate which physical and psychosocial factors are associated with physical activity and sitting time. Design: Cross-sectional study. Setting: Patients were recruited at

  2. Physical activity and breast cancer risk in Chinese women

    Pronk, A.; Ji, B. T.; X.O. Shu; Chow, W H; Xue, S.; G. Yang; Li, H. L.; Rothman, N.; Gao, Y.T. (Yu-Tang); Zheng, W.; Matthews, C.E.

    2011-01-01

    Background: The influence of different types and intensities of physical activity on risk for breast cancer is unclear. Methods: In a prospective cohort of 73 049 Chinese women (40–70 years), who had worked outside the home, we studied breast cancer risk in relation to specific types of self-reported and work history-related physical activity, including adolescent and adult exercise and household activity and walking and cycling for transportation. Occupational sitting time and physical activ...

  3. Travel Mode and Physical Activity at Sydney University

    Chris Rissel; Ding Ding; Corinne Mulley

    2013-01-01

    How staff and students travel to university can impact their physical activity level. An online survey of physical activity and travel behaviour was conducted in early November 2012 to inform planning of physical activity and active travel promotion programs at the University of Sydney, Australia as part of the “Sit Less, Move More” sub-committee of the Healthy University Initiative, and as baseline data for evaluation. There were 3,737 useable responses, 60% of which were from students. Four...

  4. Associations between active commuting and physical and mental wellbeing.

    Humphreys, DK; Goodman, A.; Ogilvie, D

    2013-01-01

    OBJECTIVE: To examine whether a relationship exists between active commuting and physical and mental wellbeing. METHOD: In 2009, cross-sectional postal questionnaire data were collected from a sample of working adults (aged 16 and over) in the Commuting and Health in Cambridge study. Travel behaviour and physical activity were ascertained using the Recent Physical Activity Questionnaire (RPAQ) and a seven-day travel-to-work recall instrument from which weekly time spent in active commuting (w...

  5. Physical Activity Energy Expenditure in Dutch Adolescents: Contribution of Active Transport to School, Physical Education, and Leisure Time Activities

    Slingerland, Menno; Borghouts, Lars B.; Hesselink, Matthijs K. C.

    2012-01-01

    Background: Detailed knowledge about physical activity energy expenditure (PAEE) can guide the development of school interventions aimed at reducing overweight in adolescents. However, relevant components of PAEE have never been objectively quantified in this population. This study investigated the contribution of active transport to and from…

  6. Impulsive approach tendencies towards physical activity and sedentary behaviors, but not reflective intentions, prospectively predict non-exercise activity thermogenesis.

    Boris Cheval

    Full Text Available Understanding the determinants of non-exercise activity thermogenesis (NEAT is crucial, given its extensive health benefits. Some scholars have assumed that a proneness to react differently to environmental cues promoting sedentary versus active behaviors could be responsible for inter-individual differences in NEAT. In line with this reflection and grounded on the Reflective-Impulsive Model, we test the assumption that impulsive processes related to sedentary and physical activity behaviors can prospectively predict NEAT, operationalized as spontaneous effort exerted to maintain low intensity muscle contractions within the release phases of an intermittent maximal isometric contraction task. Participants (n = 91 completed a questionnaire assessing their intentions to adopt physical activity behaviors and a manikin task to assess impulsive approach tendencies towards physical activity behaviors (IAPA and sedentary behaviors (IASB. Participants were then instructed to perform a maximal handgrip strength task and an intermittent maximal isometric contraction task. As hypothesized, multilevel regression analyses revealed that spontaneous effort was (a positively predicted by IAPA, (b negatively predicted by IASB, and (c was not predicted by physical activity intentions, after controlling for some confounding variables such as age, sex, usual PA level and average force provided during the maximal-contraction phases of the task. These effects remained constant throughout all the phases of the task. This study demonstrated that impulsive processes may play a unique role in predicting spontaneous physical activity behaviors. Theoretically, this finding reinforces the utility of a motivational approach based on dual-process models to explain inter-individual differences in NEAT. Implications for health behavior theories and behavior change interventions are outlined.

  7. Daily physical activity and type 2 diabetes: A review.

    Hamasaki, Hidetaka

    2016-06-25

    Physical activity improves glycemic control and reduces the risk of cardiovascular disease (CVD) and mortality in patients with type 2 diabetes (T2D). Moderate to vigorous physical activity is recommended to manage T2D; however, patients with T2D can be physically weak, making it difficult to engage in the recommended levels of physical activity. Daily physical activity includes various activities performed during both occupational and leisure time such as walking, gardening, and housework that type 2 diabetic patients should be able to perform without considerable physical burden. This review focuses on the association between daily physical activity and T2D. Walking was the most common form of daily physical activity, with numerous studies demonstrating its beneficial effects on reducing the risk of T2D, CVD, and mortality. Walking for at least 30 min per day was shown to reduce the risk of T2D by approximately 50%. Additionally, walking was associated with a reduction in mortality. In contrast, evidence was extremely limited regarding other daily physical activities such as gardening and housework in patients with T2D. Recent studies have suggested daily physical activity, including non-exercise activity thermogenesis, to be favorably associated with metabolic risks and mortality. However, well-designed longitudinal studies are warranted to elucidate its effects on overall health. PMID:27350847

  8. Factors Predicting Physical Activity Among Children With Special Needs

    Shahram Yazdani, MD

    2013-07-01

    Full Text Available Introduction Obesity is especially prevalent among children with special needs. Both lack of physical activity and unhealthful eating are major contributing factors. The objective of our study was to investigate barriers to physical activity among these children. Methods We surveyed parents of the 171 children attending Vista Del Mar School in Los Angeles, a nonprofit school serving a socioeconomically diverse group of children with special needs from kindergarten through 12th grade. Parents were asked about their child’s and their own physical activity habits, barriers to their child’s exercise, and demographics. The response rate was 67%. Multivariate logistic regression was used to examine predictors of children being physically active at least 3 hours per week. Results Parents reported that 45% of the children were diagnosed with attention deficit hyperactivity disorder, 38% with autism, and 34% with learning disabilities; 47% of children and 56% of parents were physically active less than 3 hours per week. The top barriers to physical activity were reported as child’s lack of interest (43%, lack of developmentally appropriate programs (33%, too many behavioral problems (32%, and parents’ lack of time (29%. However, child’s lack of interest was the only parent-reported barrier independently associated with children’s physical activity. Meanwhile, children whose parents were physically active at least 3 hours per week were 4.2 times as likely to be physically active as children whose parents were less physically active (P = .01. Conclusion In this group of students with special needs, children’s physical activity was strongly associated with parental physical activity; parent-reported barriers may have had less direct effect. Further studies should examine the importance of parental physical activity among children with special needs.

  9. Linking Physical Activity with Academics: Strategies for Integration

    Koch, Jennifer L.

    2013-01-01

    The purpose of this article is to highlight the need for physical activity-integrated lessons for classroom teachers, provide strategies for effective integration, and encourage physical education teachers to be an additional

  10. Self-Related Health, Physical Activity and Complaints in Swedish High School Students

    Marie Alricsson

    2006-01-01

    Full Text Available The aim of this investigation was to study self-related health, physical activity and level of exertion, as well as body complaints in Swedish high school students. A total of 993 high school students aged 16–19 years participated in the study. A questionnaire was completed at school and included questions about self-related health, physical activity behavior, type of physical activity/sport, intensity, duration, possible injuries or complaints, and absence from physical training at school, during the last 3 months. The results showed that 26% of the high school students participated in sports on a regular basis. Males reported significantly better health than females (p < 0.0005. A significantly higher number of females participated in physical activities at a lower level of effort (p < 0.0005 and a higher number of males trained at a higher level of effort (p < 0.005. Sixtyone percent reported body pain during the last 3 months, representing a higher number of females than males (p = 0.03. A higher number of females than males reported complaints from the back (p = 0.002, the knees (p = 0.015, the neck (p = 0.001, and the hip (p = 0.015. Females with body complaints reported poorer health than those without complaints. There was a correlation between poor self-related health and a lower level of physical effort (0.219; p < 0.001. The results showed that the prevalence of musculoskeletal symptoms was high in this population and demonstrated a certain association with self-related health. Therefore, it is important to make it easy for adolescents to perform physical activity at school and during their leisure time in order to prevent chronic diseases.

  11. The Value of Fun in Physical Activity

    El-Sherif, Jennifer L.

    2016-01-01

    According to students, fun, good grades and time with friends are the three key outcomes of physical education. A further review of fun in physical education, from the perspective of students, is included in this article. Selected responses from interviews with high school students reference fun as an important part of their experience in physical…

  12. International Centre for Theoretical Physics. Scientific activities in 1987

    A review of the scientific activities of the ICTP Trieste in 1987, including workshops, research and training for research is presented. The scientific program consists of eight main fields: fundamental physics, condensed matter, atomic and molecular physics, mathematics, physics and energy, physics and environment, applied physics and high technology, physics and development. In addition to a brief description of each workshop, symposium, college, meeting and activity or project sponsored by ICTP, a list of preprints and internal reports issued in 1987 is included. Tabs

  13. Physical activity for people with a disability - A conceptual model

    van der Ploeg, Hidde P; van der Beek, AJ; van der Woude, LHV; van Mechelen, W

    2004-01-01

    The promotion of a physically active lifestyle has become an important issue in health policy in first-world countries. A physically active lifestyle is accompanied by several fitness and health benefits. Individuals with a disability can particularly benefit from an active lifestyle: not only does

  14. Reliability and Validity of the Physical Education Activities Scale

    Thomason, Diane L.; Feng, Du

    2016-01-01

    Background: Measuring adolescent perceptions of physical education (PE) activities is necessary in understanding determinants of school PE activity participation. This study assessed reliability and validity of the Physical Education Activities Scale (PEAS), a 41-item visual analog scale measuring high school adolescent perceptions of school PE…

  15. Common Problems and Solutions for Being Physically Active

    ... the road again… Take workout clothes when you travel. Use your hotel's health club or pool. If there isn't one, ... Concerns • What Can I Expect? Introduction Getting Physically Active - Introduction - Physical Activity & Health - What Type of Activity is Best? - Develop a ...

  16. Physical Activity in Youth With Type 1 Diabetes: a Review.

    Tully, Carrie; Aronow, Laura; Mackey, Eleanor; Streisand, Randi

    2016-09-01

    Youth with type 1 diabetes are at risk for developing cardiovascular disease, and regular physical activity is strongly recommended as one strategy for prevention, as well as for good glycemic control. Despite recommendations, families in this pediatric population face unique barriers to physical activity, including fear of hypoglycemia. Moreover, families are not routinely counseled in the specific health and psychosocial benefits of following physical activity recommendations for youth with type 1 diabetes. To bridge this gap, the recent literature regarding physical activity in children with type 1 diabetes is reviewed with particular focus on young children. A discussion of the limitations of the current body of research, and recommendations for objectively measured physical activity are provided. Specific recommendations for clinical practice are given, including provider endorsements for regular physical activity for longer than 60 minutes, at least three times a week. PMID:27475093

  17. Space, body, time and relationship experiences of recess physical activity

    Pawlowski, Charlotte Skau; Andersen, Henriette Bondo; Tjørnhøj-Thomsen, Tine;

    2016-01-01

    and relations revealed several key factors influencing their recess physical activity: perceived classroom safety, indoor cosiness, lack of attractive outdoor facilities, bodily dissatisfaction, bodily complaints, tiredness, feeling bored, and peer influence. CONCLUSION: We found that the four existential......BACKGROUND: Increasing recess physical activity has been the aim of several interventions, as this setting can provide numerous physical activity opportunities. However, it is unclear if these interventions are equally effective for all children, or if they only appeal to children who are already...... physically active. This study was conducted to explore the least physically active children's "lived experiences" within four existential lifeworlds linked to physical activity during recess: space, body, time, and relations. METHODS: The study builds on ethnographic fieldwork in a public school in Denmark...

  18. Workshop Physics Activity Guide, Module 4: Electricity and Magnetism

    Laws, Priscilla W.

    2004-05-01

    The Workshop Physics Activity Guide is a set of student workbooks designed to serve as the foundation for a two-semester calculus-based introductory physics course. It consists of 28 units that interweave text materials with activities that include prediction, qualitative observation, explanation, equation derivation, mathematical modeling, quantitative experiments, and problem solving. Students use a powerful set of computer tools to record, display, and analyze data, as well as to develop mathematical models of physical phenomena. The design of many of the activities is based on the outcomes of physics education research. The Workshop Physics Activity Guide is supported by an Instructor's Website that: (1) describes the history and philosophy of the Workshop Physics Project; (2) provides advice on how to integrate the Guide into a variety of educational settings; (3) provides information on computer tools (hardware and software) and apparatus; and (4) includes suggested homework assignments for each unit. Log on to the Workshop Physics Project website at http://physics.dickinson.edu/ Workshop Physics is a component of the Physics Suite--a collection of materials created by a group of educational reformers known as the Activity Based Physics Group. The Physics Suite contains a broad array of curricular materials that are based on physics education research, including: Understanding Physics, by Cummings, Laws, Redish and Cooney (an introductory textbook based on the best-selling text by Halliday/Resnick/Walker) RealTime Physics Laboratory Modules Physics by Inquiry (intended for use in a workshop setting) Interactive Lecture Demonstration Tutorials in Introductory Physics Activity Based Tutorials (designed primarily for use in recitations)

  19. Can Programmed or Self-Selected Physical Activity Affect Physical Fitness of Adolescents?

    Neto Cláudio F.; Neto Gabriel R.; Araújo Adenilson T.; Sousa Maria S. C.; Sousa Juliana B. C.; Batista Gilmário R.; Reis Victor M. M. R.

    2014-01-01

    The aim of this study was to verify the effects of programmed and self-selected physical activities on the physical fitness of adolescents. High school adolescents, aged between 15 and 17 years, were divided into two experimental groups: a) a self-selected physical activity group (PAS) with 55 students (aged 15.7 ± 0.7 years), who performed physical activities with self-selected rhythm at the following sports: basketball, volleyball, handball, futsal and swimming; and b) a physical fitness tr...

  20. Perspectives on Active Video Gaming as a New Frontier in Accessible Physical Activity for Youth With Physical Disabilities.

    Rowland, Jennifer L; Malone, Laurie A; Fidopiastis, Cali M; Padalabalanarayanan, Sangeetha; Thirumalai, Mohanraj; Rimmer, James H

    2016-04-01

    This perspective article explores the utility of active video gaming as a means of reducing sedentary behavior and increasing physical activity among youth with physical disabilities and limitations in lower extremity function who typically are excluded from mainstream exercise options. Youth with physical disabilities are disproportionately affected by health problems that result from sedentary behavior, lack of physical activity, and low fitness levels. Physical, programmatic, and attitudinal barriers have a synergistic and compounded impact on youths' ability to participate in physical activity. A recent health and wellness task force recommendation from the American Physical Therapy Association's Section on Pediatrics supports analyzing individualized health behaviors and preferences that are designed to improve fitness, physical activity, and participation in pediatric rehabilitation. This recommendation represents an opportunity to explore nontraditional options to maximize effectiveness and sustainability of pediatric rehabilitation techniques for youth with disabilities who could best benefit from customized programming. One new frontier in promoting physical activity and addressing common physical activity barriers for youth with physical disabilities is active video games (AVGs), which have received growing attention as a promising strategy for promoting health and fitness in children with and without disabilities. The purpose of this article is to discuss the potential for AVGs as an accessible option to increase physical activity participation for youth with physical disabilities and limitations in lower extremity function. A conceptual model on the use of AVGs to increase physical activity participation for youth with physical disabilities is introduced, and future research potential is discussed, including a development project for game controller adaptations within the Rehabilitation Engineering Research Center on Interactive Exercise Technologies

  1. Association of physical workload and leisure time physical activity with incident mobility limitations

    Mänty, M; Møller, A; Nilsson, C;

    2014-01-01

    OBJECTIVES: To examine individual as well as joint associations of physical workload and leisure time physical activity with incident mobility limitations in initially well-functioning middle-aged workers. METHODS: This study is based on 6-year follow-up data of the Danish Longitudinal Study on...... Work, Unemployment and Health. Physical workload was reported at baseline and categorised as light, moderate or heavy. Baseline leisure time physical activity level was categorised as sedentary or active following the current recommendations on physical activity. Incidence of mobility limitations in...... with higher workload regardless of level of leisure time physical activity, although the risks tended to be higher among those with sedentary leisure time compared with their active counterparts. All in all, the risk for onset of mobility limitations was highest among those with heavy workload combined...

  2. Physical activity and associated factors among students attending evening classes

    Fabio Luis Ceschini

    2015-03-01

    Full Text Available The aim of this study was to describe the physical activity level and associated factors among students attending evening classes in public and private schools in a region of the city of São Paulo. The sample was composed of 1,844 adolescents of both sexes aged 15-20 years. Three public and private schools in the city of São Paulo were visited. Daily physical activity level was assessed through International Physical Activity Questionnaire that classifies physical activity level. Physical activity level was divided into insufficiently active (when subject reported less than 300 minutes of moderate to vigorous physical activities per week and physically active (when subject reported more than 300 minutes of moderate to vigorous physical activities per week. Information related to risk behavior such as smoking and alcohol consumption was collected. Data were analyzed using logistic regression with three levels of data input and p<.05 as significance level. The prevalence of physically active adolescents was 36.1%. Most active subjects were: A younger boys with low socioeconomic levels; B adolescents from private schools; C adolescents that do not smoke or drink alcoholic beverages; D those who do not attend formal exercise program; E those who go to school to perform physical activities on weekends. Adolescents attending evening classes tended to be insufficiently active. We believe that school structure, working hours, and distance from home and workplace to school and risk factor should explain these data. Intervention programs could significantly contribute to increase the physical activity level among adolescents.

  3. Determinants of Change in Physical Activity in Children and Adolescents

    Craggs, Christopher; Corder, Kirsten; van Sluijs, Esther M. F.; Simon J Griffin

    2011-01-01

    Context Data are available on correlates of physical activity in children and adolescents, less is known about the determinants of change. This review aims to systematically review the published evidence regarding determinants of change in physical activity in children and adolescents. Evidence acquisition Prospective quantitative studies investigating change in physical activity in children and adolescents aged 4–18 years were identified from seven databases (to November 2010): PubMed, SCOPU...

  4. The relation of physical activity and exercise to mental health.

    Taylor, C. B.; Sallis, J F; Needle, R.

    1985-01-01

    Mental disorders are of major public health significance. It has been claimed that vigorous physical activity has positive effects on mental health in both clinical and nonclinical populations. This paper reviews the evidence for this claim and provides recommendations for future studies. The strongest evidence suggests that physical activity and exercise probably alleviate some symptoms associated with mild to moderate depression. The evidence also suggests that physical activity and exercis...

  5. Physical activity as an important determinant in developing childhood obesity

    Bukara-Radujković Gordana; Zdravković Dragan

    2009-01-01

    The correlation between physical activity and sedentary life style was investigated as a determinant of the body mass index in children and adolescents in Banjaluka region. The study involved 1204 children and adolescents, 6-17 years old, 578 boys, 626 girls. BMI was calculated from their height and weight using standard formula. Each child, together with their parents answered the questions considering their level of involvement in physical versus sedentary activities. Physical activity was ...

  6. Summary of International Guidelines for Physical Activity Following Pregnancy

    Evenson, Kelly R.; Mottola, Michelle F.; Owe, Katrine M.; Rousham, Emily K.; Brown, Wendy J.

    2014-01-01

    Postpartum physical activity can improve mood, maintain cardiorespiratory fitness, improve weight control, promote weight loss, and reduce depression and anxiety. This review summarizes current guidelines for postpartum physical activity worldwide. PubMed (MedLINE) was searched for country-specific government and clinical guidelines on physical activity following pregnancy through the year 2013. Only the most recent guideline was included in the review. An abstraction form facilitated extract...

  7. Correlates of Physical Activity in Asian Adolescents: A Literature Review

    Husna Hidayati; Urai Hatthakit; Sang-Arun Isaramalai

    2012-01-01

    Background: Physical activity is important to prevent several chronic diseases in adulthood. Nowadays, young people do not regularly perform physical activity. Several factors may influence their decision. Most of studies were conducted in western countries. However the findings might not be generalized regarding the differences in culture and social condition. Therefore, reviewing the correlates of physical activity among adolescents in Asian countries is essential. Purpose: To update the st...

  8. Physical activity and healthy lifestyle in Canarian teenagers

    Navarro Valdivielso, Manuel; Ojeda García, Roberto; Navarro Hernández, Miriam; López López, Eduardo; Brito Ojeda, Estrella; Ruiz Caballero, José Antonio

    2012-01-01

    The present study about adolescent from the Canary Islands, evidence that a minority of adolescents follow the guidelines or recommendations for physical activity, showing low level of physical activity of moderate intensity and vigorous, levels which are shown away from the established recommendations for this group of age, and insufficient to attain the positive effects arising from the practice of physical activity, and these low levels are more accentuated in girls than in boys. These evi...

  9. Physical activity and brain plasticity in late adulthood

    Erickson, Kirk I.; Gildengers, Ariel G.; Butters, Meryl A.

    2013-01-01

    The human brain shrinks with advancing age, but recent research suggests that it is also capable of remarkable plasticity, even in late life. In this review we summarize the research linking greater amounts of physical activity to less cortical atrophy, better brain function, and enhanced cognitive function, and argue that physical activity takes advantage of the brain's natural capacity for plasticity. Further, although the effects of physical activity on the brain are relatively widespread,...

  10. Physical Activity, Brain Plasticity, and Alzheimer’s Disease

    Erickson, Kirk I.; Weinstein, Andrea M.; Lopez, Oscar L.

    2012-01-01

    In this review we summarize the epidemiological, cross-sectional, and interventional studies examining the association between physical activity and brain volume, function, and risk for Alzheimer’s disease. The epidemiological literature provides compelling evidence that greater amounts of physical activity are associated with a reduced risk of dementia in late life. In addition, randomized interventions using neuroimaging tools have reported that participation in physical activity increases ...

  11. A study of predictors of adolescents’ physical activity intentions

    Haralambos Tsorbatzoudis; Despoina Ourda; Vassilis Barkoukis; Lambros Lazuras

    2011-01-01

    The present study used an integrated theoretical framework based on the Theory of Planned Behaviour and the Prototype/Willingness model to examine the social cognitive predictors of leisure time physical activity intentions among Greek secondary school students (N = 254, M age = 13.59 years, SD = 1.18). A cross-sectional survey method was employed to assess physical activity intentions and related psychosocial beliefs, as well as self-reported physical activity behaviour. Multiple regression ...

  12. Barriers to Physical Activity Among Patients With Type 1 Diabetes

    Brazeau, Anne-Sophie; Rabasa-Lhoret, Rémi; Strychar, Irene; Mircescu, Hortensia

    2008-01-01

    OBJECTIVE—To determine, in an adult population with type 1 diabetes, barriers to regular physical activity using a diabetes-specific barriers measure (the Barriers to Physical Activity in Diabetes [type 1] [BAPAD1] scale) and factors associated with these barriers. RESEARCH DESIGN AND METHODS—One hundred adults with type 1 diabetes answered a questionnaire assessing perceived barriers to physical activity and related factors. A1C was obtained from the medical chart of each individual. RESULTS...

  13. Multiple myeloma and physical activity: a scoping review

    Smith, L; McCourt, O.; Heinrich, M.; Paton, B.; Yong, K.; Wardle, J; Fisher, A.

    2015-01-01

    Objectives: Multiple myeloma is the second most common haematological cancer. A growing body of literature is emerging that investigates the role physical activity plays in all stages of multiple myeloma (prevention and survivorship) and to date no attempt has been made to collate and understand this literature. Therefore, this scoping review aims to (1) outline what is already known about physical activity in all stages of multiple myeloma (2) map the literature on physical activity and mult...

  14. Increased physical activity, physician recommendation, and senior center participation

    Swan, James H.; Keith Turner; Shilpa Shashidhara; David Sanders

    2013-01-01

    Physical activity is a recognized preventive health measure for seniors and an important focus for senior centers. This paper employs the Andersen Behavioral Model to explore increased physical activity and participation in three types of senior center activities: physical fitness, dance/aerobic classes, and chair exercises. Data were collected in 2006 on 798 and in 2007 on 742 participants at 21 multipurpose senior centers in a large urban county. Logistic regression analysis (PROC RLOG...

  15. Physical activity barriers and facilitators among working mothers and fathers

    Mailey, Emily L.; Huberty, Jennifer; Dinkel, Danae; McAuley, Edward

    2014-01-01

    Background The transition to parenthood is consistently associated with declines in physical activity. In particular, working parents are at risk for inactivity, but research exploring physical activity barriers and facilitators in this population has been scarce. The purpose of this study was to qualitatively examine perceptions of physical activity among working parents. Methods Working mothers (n = 13) and fathers (n = 12) were recruited to participate in one of four focus group sessions a...

  16. Gene–Physical Activity Interactions: Overview of Human Studies

    Rankinen, Tuomo; Bouchard, Claude

    2008-01-01

    Physical activity level is an important component of the total daily energy expenditure and as such contributes to body weight regulation. A body of data indicates that the level of physical activity plays a role in the risk of excessive weight gain, in weight loss programs, and particularly in the prevention of weight regain. Most studies dealing with potential gene–physical activity interaction effects use an exercise and fitness or performance paradigm as opposed to an obesity-driven model...

  17. The effects of the quantity of physical activity in cognition

    Susano, João Paulo Gomes

    2014-01-01

    Mestrado em Exercício e Saúde Exercise promotes the increase of cognitive performance (Aberg et al., 2009), however, the quantity of physical activity needed to achieve this effect is not clearly defined. The present study aimed to research the effects of the quantity of physical activity practice on the executive function of healthy adults, measured by performance on the Stroop test. Results showed that the sedentary group had a worst performance than both groups of physically active indi...

  18. Effects of fitness and self-confidence on time perception during exertion

    2015-09-01

    Full Text Available Aims: Human physical and psychological features influence perceptions of the environment during activity. If during exercise an individual over-estimates time, they may interpret this as spending longer than necessary under a potentially aversive state of exertion. This may in turn decrease one’s sense of exercise success and tendency to persevere with exercise. We tested if experimentally manipulating sense of exercise self-efficacy would affect time perception during standardised physical exertion. Method: Exercise Self-Efficacy (ESE of 18 -73 year olds (N=51 was measured before and after an exercise challenge of moderate intensity. Height, weight and body fat composition were measured before participants were randomly allocated to one of three groups. After a 4-minute treadmill fitness test, participants were presented with either bogus feedback about their performance (positive or negative or no feedback (control. Before and during exercise, participants estimated a prescribed 2-minute time interval. Ratings of perceived exertion were also measured periodically. Results: Feedback on performance had no significant effect on time perception, even when controlling for individual exertion level. Reported ESE was also unaffected by whether someone received positive, negative or no feedback. Age was again found to be significantly correlated with VO2max, r(51 = .62, p < .001, but in contrast to prior findings, estimates of general fitness such as VO2max, BMI and waist circumference were unrelated to changes in time perception due to exertion. Conclusions: These findings failed to support prior findings and anecdotal evidence suggesting that exertion might alter one’s perception of time. We also failed to find any support for effects on ESE when participants were given explicit performance feedback. Finally, participants’ physical characteristics appear to be unrelated to time perception whilst exercising at moderate intensity.

  19. THE EFFECTS OF EXERGAMING ON PHYSICAL ACTIVITY AMONG INACTIVE CHILDREN IN A PHYSICAL EDUCATION CLASSROOM

    Fogel, Victoria A; Miltenberger, Raymond G.; Graves, Rachel; Koehler, Shannon

    2010-01-01

    Childhood obesity, which is due in part to lack of physical activity, is a serious concern that requires the attention of the behavioral community. Although excessive video game play has been noted in the literature as a contributor to childhood obesity, newer video gaming technology, called exergaming, has been designed to capitalize on the reinforcing effects of video games to increase physical activity in children. This study evaluated the effects of exergaming on physical activity among 4...

  20. Adolescent physical activity and health: a systematic review.

    Hallal, Pedro C; Victora, Cesar G; Azevedo, Mario R; Wells, Jonathan C K

    2006-01-01

    Physical activity in adolescence may contribute to the development of healthy adult lifestyles, helping reduce chronic disease incidence. However, definition of the optimal amount of physical activity in adolescence requires addressing a number of scientific challenges. This article reviews the evidence on short- and long-term health effects of adolescent physical activity. Systematic reviews of the literature were undertaken using a reference period between 2000 and 2004, based primarily on the MEDLINE/PubMed database. Relevant studies were identified by examination of titles, abstracts and full papers, according to inclusion criteria defined a priori. A conceptual framework is proposed to outline how adolescent physical activity may contribute to adult health, including the following pathways: (i) pathway A--tracking of physical activity from adolescence to adulthood; (ii) pathway B--direct influence of adolescent physical activity on adult morbidity; (iii) pathway C--role of physical activity in treating adolescent morbidity; and (iv) pathway D - short-term benefits of physical activity in adolescence on health. The literature reviews showed consistent evidence supporting pathway 'A', although the magnitude of the association appears to be moderate. Thus, there is an indirect effect on all health benefits resulting from adult physical activity. Regarding pathway 'B', adolescent physical activity seems to provide long-term benefits on bone health, breast cancer and sedentary behaviours. In terms of pathway 'C', water physical activities in adolescence are effective in the treatment of asthma, and exercise is recommended in the treatment of cystic fibrosis. Self-esteem is also positively affected by adolescent physical activity. Regarding pathway 'D', adolescent physical activity provides short-term benefits; the strongest evidence refers to bone and mental health. Appreciation of different mechanisms through which adolescent physical activity may influence adult

  1. Validation of the historical adulthood physical activity questionnaire (HAPAQ against objective measurements of physical activity

    McDermott Christopher J

    2010-06-01

    Full Text Available Abstract Background Lifetime physical activity energy expenditure (PAEE is an important determinant of risk for many chronic diseases but remains challenging to measure. Previously reported historical physical activity (PA questionnaires appear to be reliable, but their validity is less well established. Methods We sought to design and validate an historical adulthood PA questionnaire (HAPAQ against objective PA measurements from the same individuals. We recruited from a population-based cohort in Cambridgeshire, UK, (Medical Research Council Ely Study in whom PA measurements, using individually calibrated heart rate monitoring, had been obtained in the past, once between 1994 and 1996 and once between 2000 and 2002. 100 individuals from this cohort attended for interview. Historical PA within the domains of home, work, transport, sport and exercise was recalled using the questionnaire by asking closed questions repeated for several discrete time periods from the age of 20 years old to their current age. The average PAEE from the 2 periods of objective measurements was compared to the self-reported data from the corresponding time periods in the questionnaire. Results Significant correlations were observed between HAPAQ-derived and objectively measured total PAEE for both time periods (Spearman r = 0.44; P Conclusions HAPAQ demonstrates convergent validity for total PAEE and vigorous PA. This instrument will be useful for ranking individuals according to their past PA in studies of chronic disease aetiology, where activity may be an important underlying factor contributing to disease pathogenesis.

  2. Do attributes in the physical environment influence children's physical activity? A review of the literature

    Lawson Catherine T

    2006-07-01

    Full Text Available Abstract Background Many youth today are physically inactive. Recent attention linking the physical or built environment to physical activity in adults suggests an investigation into the relationship between the built environment and physical activity in children could guide appropriate intervention strategies. Method Thirty three quantitative studies that assessed associations between the physical environment (perceived or objectively measured and physical activity among children (ages 3 to 18-years and fulfilled selection criteria were reviewed. Findings were categorized and discussed according to three dimensions of the physical environment including recreational infrastructure, transport infrastructure, and local conditions. Results Results across the various studies showed that children's participation in physical activity is positively associated with publicly provided recreational infrastructure (access to recreational facilities and schools and transport infrastructure (presence of sidewalks and controlled intersections, access to destinations and public transportation. At the same time, transport infrastructure (number of roads to cross and traffic density/speed and local conditions (crime, area deprivation are negatively associated with children's participation in physical activity. Conclusion Results highlight links between the physical environment and children's physical activity. Additional research using a transdisciplinary approach and assessing moderating and mediating variables is necessary to appropriately inform policy efforts.

  3. Physical activity increases survival after heart valve surgery

    Lund, K; Sibilitz, K L; Berg, S K;

    2016-01-01

    OBJECTIVES: Increased physical activity predicts survival and reduces risk of readmission in patients with coronary heart disease. However, few data show how physical activity is associated with survival and readmission after heart valve surgery. Objective were to assess the association between...... physical activity levels 6-12 months after heart valve surgery and (1) survival, (2) hospital readmission 18-24 months after surgery and (3) participation in exercise-based cardiac rehabilitation. METHODS: Prospective cohort study with registry data from The CopenHeart survey, The Danish National Patient...... Register and The Danish Civil Registration System of 742 eligible patients. Physical activity was quantified with the International Physical Activity Questionnaire and analysed using Kaplan-Meier analysis and Cox regression and logistic regression methods. RESULTS: Patients with a moderate to high physical...

  4. Pedometer-Determined Physical Activity and Its Comparison with the International Physical Activity Questionnaire in a Sample of Belgian Adults

    De Cocker, Katrien; Cardon, Greet; De Bourdeaudhuij, Ilse

    2007-01-01

    Pedometer-determined physical activity (PA) levels in Belgian adults were provided and compared to PA scores reported in the International Physical Activity Questionnaire (IPAQ). The representative sample (N = 1,239) of the Belgian population took on average 9,655 (4,526) steps/day. According to pedometer indices 58.4% were insufficiently active.…

  5. Longitudinal changes in physical self-perceptions and associations with physical activity during adolescence.

    Inchley, Jo; Kirby, Jo; Currie, Candace

    2011-05-01

    The purpose of this study was to examine adolescents' physical self-perceptions and their associations with physical activity using a longitudinal perspective. Utilizing data from the Physical Activity in Scottish Schoolchildren (PASS) study, changes in exercise self-efficacy, perceived competence, global self-esteem and physical self-worth were assessed among a sample of 641 Scottish adolescents from age 11-15 years. Girls reported lower levels of perceived competence, self-esteem and physical self-worth than boys at each age. Furthermore, girls' physical self-perceptions decreased markedly over time. Among boys, only perceived competence decreased, while global self-esteem increased. Baseline physical activity was a significant predictor of later activity levels for both genders. Findings demonstrate the importance of physical self-perceptions in relation to physical activity behavior among adolescents. Among older boys, high perceived competence increased the odds of being active by 3.8 times. Among older girls, high exercise self-efficacy increased the odds of being active by 5.2 times. There is a need for early interventions which promote increased physical literacy and confidence, particularly among girls. PMID:21633136

  6. Do Motives to Undertake Physical Activity Relate to Physical Activity in Adolescent Boys and Girls?

    Jaroslava Kopcakova; Zuzana Dankulincova Veselska; Andrea Madarasova Geckova; Michal Kalman; van Dijk, Jitse P.; Reijneveld, Sijmen A.

    2015-01-01

    Low levels of physical activity (PA) during adolescence contribute to obesity and poor health outcomes in adolescence, and these associations endure into adulthood. The aim of this study was to assess the associations between motives for PA and the level of PA among adolescent boys and girls. We obtained data regarding motives for PA and frequency of PA in 2010 via the Health Behavior in School-aged Children cross-sectional study in the Czech and Slovak Republics (n = 9018, mean age = 13.6, 4...

  7. Effects of individually tailored physical and daily activities in nursing home residents on activities of daily living, physical performance and physical activity level

    Andresen, Mette; Frändin, Kerstin; Bergland, Astrid;

    2012-01-01

    Background: Nursing home residents are extremely inactive and deterioration in health and an increasing dependence in activities of daily living (ADL) are common. Physical activity and exercise play a major role in the preservation of physical function and quality of life late in life. However......, evidence for the benefit of rehabilitation in nursing home residents is conflicting and inconclusive. Objective: To evaluate the effect of an individually tailored intervention program of 3 months, for nursing home residents, on ADL, balance, physical activity level, mobility and muscle strength. Methods......: In this single-blind randomized clinical trial with parallel groups, nursing home residents 1 64 years of age from three Nordic countries were included. The intervention group (IG) was assigned to individually tailored physical and daily activities, while the control group (CG) received ordinary care...

  8. Active Kids Active Minds: A Physical Activity Intervention to Promote Learning?

    lisahunter; Abbott, Rebecca; Macdonald, Doune; Ziviani, Jennifer; Cuskelly, Monica

    2014-01-01

    This study assessed the feasibility and impact of introducing a programme of an additional 30 minutes per day of moderate physical activity within curriculum time on learning and readiness to learn in a large elementary school in south-east Queensland, Australia. The programme, Active Kids Active Minds (AKAM), involved Year 5 students (n = 107),…

  9. The Effect of Outdoor Activity Context on Physical Activity in Preschool Children

    Hustyi, Kristin M.; Normand, Matthew P.; Larson, Tracy A.; Morley, Allison J.

    2012-01-01

    The purpose of the current study was to develop and test a method for assessing the effect of outdoor activity context on level of physical activity in preschool children. The Observational System for Recording Physical Activity in Children was used to define the test conditions and various levels of physical activity within a multielement design.…

  10. Adiposity and Age Explain Most of the Association between Physical Activity and Fitness in Physically Active Men

    Serrano-Sánchez, José A.; Safira Delgado-Guerra; Hugo Olmedillas; Amelia Guadalupe-Grau; Rafael Arteaga-Ortiz; Joaquín Sanchis-Moysi; Cecilia Dorado; Calbet, José A. L.

    2010-01-01

    BACKGROUND: To determine if there is an association between physical activity assessed by the short version of the International Physical Activity Questionnaire (IPAQ) and cardiorespiratory and muscular fitness. METHODOLOGY/PRINCIPAL FINDINGS: One hundred and eighty-two young males (age range: 20-55 years) completed the short form of the IPAQ to assess physical activity. Body composition (dual-energy X-Ray absorptiometry), muscular fitness (static and dynamic muscle force and power, vertical ...

  11. Physical activity and pancreatic cancer risk: a systematic review

    Bao, Ying; Michaud, Dominique S.

    2016-01-01

    Background Physical activity has been associated with a lower risk of pancreatic cancer in several studies, but the overall epidemiologic evidence is not consistent. We therefore performed a systematic review to evaluate the association between physical activity and pancreatic cancer risk. Methods We searched MEDLINE and EMBASE through April 2008 and examined the reference lists of the retrieved articles. We excluded studies that relied on job titles as surrogate measures for physical activity. We used a random-effects model to pool study-specific risk estimates comparing the highest versus the lowest category of physical activity. Results Total physical activity (occupational and leisure-time) was not significantly associated with risk of pancreatic cancer (4 prospective studies; summary relative risk (RR) = 0.76, 95% confidence interval (CI) = 0.53-1.09). A decreased risk of pancreatic cancer was observed for occupational physical activity (3 prospective studies; RR = 0.75, 95% CI = 0.58-0.96) but not for leisure-time physical activity (14 prospective studies; RR = 0.94, 95% CI = 0.83-1.05). No association was found with light physical activity (2 prospective studies; RR = 1.01, 95% CI = 0.77-1.34), moderate physical activity (6 prospective studies; RR = 0.83, 95% CI = 0.58-1.18) or vigorous physical activity (7 prospective studies; RR = 0.94, 95% CI = 0.80-1.12). Conclusions This systematic review does not provide strong evidence for an association between physical activity and risk of pancreatic cancer. PMID:18843009

  12. Insulin and insulin-like growth factor I exert different effects on plasminogen activator production or cell growth in the ovine thyroid cell line OVNIS.

    Degryse, B; Maisonobe, F; Hovsépian, S; Fayet, G

    1991-11-01

    Insulin and Insulin-like Growth Factor I (IGF-I) are evaluated for their capacity to affect cell proliferation and plasminogen activator (PA) activity production in an ovine thyroid cell line OVNIS. Insulin at physiological and supraphysiological doses induces cell proliferation and increases PA activity. IGF-I, which is also clearly mitogenic for these cells, surprisingly does not modulate PA activity. The results indicate that the growth promoting effect is mediated through the insulin and IGF-I receptors whereas PA activity is solely regulated via the insulin receptors. PMID:1802921

  13. An artificial neural network to estimate physical activity energy expenditure and identify physical activity type from an accelerometer

    Staudenmayer, John; Pober, David; Crouter, Scott; Bassett, David; Freedson, Patty

    2009-01-01

    The aim of this investigation was to develop and test two artificial neural networks (ANN) to apply to physical activity data collected with a commonly used uniaxial accelerometer. The first ANN model estimated physical activity metabolic equivalents (METs), and the second ANN identified activity type. Subjects (n = 24 men and 24 women, mean age = 35 yr) completed a menu of activities that included sedentary, light, moderate, and vigorous intensities, and each activity was performed for 10 mi...

  14. Fitness Testing in Physical Education--A Misdirected Effort in Promoting Healthy Lifestyles and Physical Activity?

    Cale, Lorraine; Harris, Jo

    2009-01-01

    Background: Physical fitness testing is commonplace within schools and the physical education (PE) curriculum, with advocates claiming one of the key purposes of testing to be the promotion of healthy lifestyles and physical activity. Despite this, much controversy has surrounded the fitness testing of young people. Purpose: This paper draws on…

  15. Physical fitness related to age and physical activity in older persons

    van Heuvelen, M.J.G.; Kempen, G.I.J.M.; Ormel, J.; Rispens, P

    1998-01-01

    Objective: This study investigated physical fitness as a function of age and leisure time physical activity (LTPA) in a community-based sample of 624 persons aged 57 yr and older. Methods: LTPA during the last 12 months was assessed through personal interviews. A wide range of physical fitness compo

  16. Relationship between Motivation and Learning in Physical Education and After-School Physical Activity

    Chen, Senlin; Sun, Haichun; Zhu, Xihe; Chen, Ang

    2014-01-01

    Purpose: A primary goal of physical education is to develop physically literate individuals with the knowledge, skills, and confidence necessary for a physically active lifestyle. Guided by the expectancy-value and interest motivation theories, the purpose of this study was to identify the relationship between students' motivation and…

  17. How Do Adults With Down Syndrome Perceive Physical Activity?

    Love, Adam; Agiovlasitis, Stamatis

    2016-07-01

    Adults with Down syndrome (DS) tend to have low physical activity levels, which may relate to how they perceive participation in physical activities. The current study entailed interviews with 30 adults with DS (age 18-71 yr, 18 women) to examine how they perceived physical activity, exercise, and sport. Through qualitative analysis informed by grounded theory, the investigators found that adults with DS have positive perceptions of physical activity that center on enjoyment. Three facets of enjoyment were identified: interaction, achievement, and process. Interaction reflected enjoyment of social contact with others including relatives, peers, caregivers, and animals. Achievement involved enjoyment of achieving particular ends including accomplishment of tasks, material rewards, formation of athletic identities, and improvement of health. Process represented enjoyment from performing a particular activity itself. This multifaceted enjoyment expressed by adults with DS may facilitate physical activity and should be considered when developing programs to improve their well-being. PMID:27623609

  18. Study on the physical activity level of Turkish males

    Ramiz Arabacı

    2008-12-01

    Full Text Available The aim of this study was to investigate physical activity (PA level of the Turkish males who lived in BUrsa. A total of 365 subjects between 18 - 69 age participated to this study. To determine physical activity levels, International Physical Activity Questionnaire (IPAQ was applied. PA levels of subjects were categorized as inactive, minimum active and HEPA active by using MET method. The relations of parameters, such as their age, BMI, education, marital status, number of children, smoking and alcohol use were determined with PA level. The results were analyzed by using Chi - Square test. The participants have 1725 METmin/week average physical activity level, and 47.7 % of them were physically inactive, 30.4 % were physically minimum active and 21.9 % were physically hepa active. As a result, it can be said that the physical activity levels of Turkish males who lived in Bursa are not sufficient and the inactive people are very common.

  19. An evolving perspective on physical activity counselling by medical professionals

    McPhail Steven

    2012-04-01

    Full Text Available Abstract Background Physical inactivity is a modifiable risk factor for many chronic conditions and a leading cause of premature mortality. An increasing proportion of adults worldwide are not engaging in a level of physical activity sufficient to prevent or alleviate these adverse effects. Medical professionals have been identified as potentially powerful sources of influence for those who do not meet minimum physical activity guidelines. Health professionals are respected and expected sources of advice and they reach a large and relevant proportion of the population. Despite this potential, health professionals are not routinely practicing physical activity promotion. Discussion Medical professionals experience several known barriers to physical activity promotion including lack of time and lack of perceived efficacy in changing physical activity behaviour in patients. Furthermore, evidence for effective physical activity promotion by medical professionals is inconclusive. To address these problems, new approaches to physical activity promotion are being proposed. These include collaborating with community based physical activity behaviour change interventions, preparing patients for effective brief counselling during a consultation with the medical professional, and use of interactive behaviour change technology. Summary It is important that we recognise the latent risk of physical inactivity among patients presenting in clinical settings. Preparation for improving patient physical activity behaviours should commence before the consultation and may include physical activity screening. Medical professionals should also identify suitable community interventions to which they can refer physically inactive patients. Outsourcing the majority of a comprehensive physical activity intervention to community based interventions will reduce the required clinical consultation time for addressing the issue with each patient. Priorities for future research

  20. Physical activity in Dublin children aged 7–9 years

    Hussey, J; Gormley, J; Bell, C

    2001-01-01

    Objectives—To investigate the amount of regular activity and time spent in sedentary occupations in children aged 7–9 years. Sex differences in levels of activity and time and facilities for physical education at school were also examined.

  1. International Centre for Theoretical Physics, Trieste. Scientific activities in 1995

    The annual report of the International Centre for Theoretical Physics from Trieste for 1995 contains three parts. Part 1 includes statistical data on the main activities of the Centre. Part 2 presents the scientific programme in various fields (Physics of Condensed Matter, Physics of High and Intermediate Energies, Mathematics, Physics and Energy, Physics of the Environment, Physics of Living State, Applied Physics and Miscellaneous) as well as other activities such as diploma course, long-term scientific visitors, associate members and federation arrangements, training and research at Italian laboratories, external activities, books and equipment donation programme, awards, and meetings hosted. Part 3 lists the publications issued in 1995 and gives information about the library of the Centre. 6 tabs

  2. [Why regular physical activity favors longevity].

    Pentimone, F; Del Corso, L

    1998-06-01

    Regular physical exercise is useful at all ages. In the elderly, even a gentle exercise programme consisting of walking, bicycling, playing golf if performed constantly increases longevity by preventing the onset of the main diseases or alleviating the handicaps they may have caused. Cardiovascular diseases, which represent the main cause of death in the elderly, and osteoporosis, a disabling disease potentially capable of shortening life expectancy, benefit from physical exercise which if performed regularly well before the start of old age may help to prevent them. Over the past few years there has been growing evidence of the concrete protection offered against neoplasia and even the ageing process itself. PMID:9739351

  3. Asthma & Physical Activity in the School

    ... Some students experience asthma symptoms only when they exercise. Asthma varies from student to student and often from ... activities and other regular school activities. Table 1: BENEFITS OF ASTHMA CONTROL With good asthma management, students with asthma ...

  4. Predicting Child Physical Activity and Screen Time: Parental Support for Physical Activity and General Parenting Styles

    Crain, A. Lauren; Senso, Meghan M.; Levy, Rona L.; Sherwood, Nancy E.

    2014-01-01

    Objective: To examine relationships between parenting styles and practices and child moderate-to-vigorous physical activity (MVPA) and screen time. Methods: Participants were children (6.9 ± 1.8 years) with a body mass index in the 70–95th percentile and their parents (421 dyads). Parent-completed questionnaires assessed parental support for child physical activity (PA), parenting styles and child screen time. Children wore accelerometers to assess MVPA. Results: Parenting style did not predict MVPA, but support for PA did (positive association). The association between support and MVPA, moreover, varied as a function of permissive parenting. For parents high in permissiveness, the association was positive (greater support was related to greater MVPA and therefore protective). For parents low in permissiveness, the association was neutral; support did not matter. Authoritarian and permissive parenting styles were both associated with greater screen time. Conclusions: Parenting practices and styles should be considered jointly, offering implications for tailored interventions. PMID:24812256

  5. RELATIONSHIPS BETWEEN PHYSICAL EDUCATION STUDENTS' MOTIVATIONAL PROFILES, ENJOYMENT, STATE ANXIETY, AND SELF-REPORTED PHYSICAL ACTIVITY

    Sami Yli-Piipari

    2009-09-01

    Full Text Available The purpose of this study was to analyze motivational profiles based on the self-determination theory (Deci and Ryan, 2000 and how these profiles are related to physical education students' enjoyment, state anxiety, and physical activity. The participants, 429 sixth grade students (girls = 216; boys = 213 completed SMS, Sport Enjoyment Scale, PESAS, and Physical Activity Scale. Cluster analyses identified two motivational profiles: 1 the "High motivation profile", in which the students had high intrinsic and extrinsic motivation, and low levels of amotivation, and 2 the "Low motivation profile", in which the students had low intrinsic and extrinsic motivation, and low levels of amotivation. The students in the first cluster enjoyed physical education more and were physically more active. The results revealed that students may be motivated towards physical education lessons both intrinsically and extrinsically, and still experience enjoyment in physical education.

  6. Physical Activity - A Neat Solution to An Impending Crisis

    Alison M. McManus

    2007-01-01

    Childhood obesity is arguably the most significant global public health threat, yet effective strategies to contain or prevent the disease are not available. This review examines the physical activity patterns of children and the role physical activity plays in daily energy expenditure. The prevailing focus on moderate to vigorous activity in childhood means there is limited objective information on either sedentary behaviour or non-exercise activity thermogenesis (NEAT), the energy expended ...

  7. Persistent Focal Behavior and Physical Activity Performance

    Erfle, Stephen E.

    2014-01-01

    This article examines the proclivity and performance attributes of focal students across time and activities using data from 9,345 students. Three systematic focal behavior partitions are examined: Across activities, across time, and across activities and time. A student's performance is focal if it ends in 0 or 5 for push-ups and 0 for…

  8. The Effect of Physical Education Climates on Elementary Students’ Physical Activity Behaviors

    Wadsworth, Danielle D.; Robinson, Leah E.; Rudisill, Mary E.; Gell, Nancy

    2013-01-01

    BACKGROUND With the growing need for children from underserved populations to be physically active it is imperative to create developmentally appropriate and enjoyable physical education programs that promote physical activity. The purpose of this study was to determine the effects of mastery and performance climates on physical activity during physical education. METHODS Children (N = 108) in grades K-2 from a rural southeastern elementary school in the US were randomly assigned to a mastery or performance oriented climate. The climates were implemented over 10 school days during regular scheduled physical education classes, and physical activity was measured with pedometers and SOFIT. Two experts in mastery motivational climates served as teachers for the study and were counterbalanced between conditions. RESULTS Results showed that steps/minute were significantly higher for the mastery condition and participants in the mastery condition spent significantly less time sitting (p < .001) and in management (p < .001) and more time in moderate-to-vigorous physical activity (MVPA; p = .002) and fitness activities (p = .001). CONCLUSION Results indicate that a mastery approach, which allows children the opportunity to drive their own physical activity, elicits higher step counts and more time spent in MVPA compared to a performance-oriented approach. PMID:23516997

  9. Physical activity as a component of students' life quality.

    Pavlova Iu.A.

    2011-01-01

    Full Text Available The model of students' life quality and its basic components were described. Among this components are: objective (level of physical fitness and daily physical activity, financial status, opportunities to improve professional skills or obtain a certain academic level, etc. and subjective (health, satisfaction with own lives, optimism, feeling of happiness, tasks and results, relationships with others, etc.. The positive influence of physical training on physical and mental capacity of students were investigated.

  10. A STATUS OF PHYSICAL ACTIVITY LIFE STYLE ACADEMY STUDENTS PHYSICAL EDUCATION AND SPORT IN GDANSK

    Prusik, Katarzyna; Zaporozhanov, Vadym; Gцrner, Karol; Prusik, Krzysztof

    2009-01-01

    Based on the results of the analysis reached different conclusions. In a separate research problem with the physical activity mandatory time off, it was found that the vast majority of students spend their time actively, mostly a form of physical activity should be aerobic / fitness and gym. In the next issue, that associates the active leisure tourism, it was found that tourism is not unknown more than half of foreign students, in addition were taken hiking, biking and skiing. In the next is...

  11. Physical Activity for Low-Income Children

    Greenberg, Jayne; Silvestri, Lynette

    2007-01-01

    With increasing demands placed on academic achievement and limited time during the school day, school administrators struggle to implement daily physical education for all students. As this trend becomes more prevalent, community-based organizations need to come forward to offer more after school and weekend programs to assist youth in achieving…

  12. Ideas and Activities for Physical Science.

    Chiappetta, Eugene L., Ed.

    This manual is designed to supplement an existing physical science curriculum and to assist in providing the learning experiences required to implement an effective course. The first chapter outlines the purposes of this manual and provides a set of teaching tips. Topics such as electricity, wave motion, light, sound, periodic table and nuclear…

  13. Relationships between physical activity, physical fitness, somatic fitness, and coordination along childhood and adolescence

    João Paulo Saraiva

    2010-12-01

    Full Text Available The two main goals of this review were to understand how the relationships between physical activity, physical fitness, somatic fitness, and coordination are established along the motor development of children and adolescents, and how they would influence their future lives. The web based bibliographic database B-On was searched for peer-reviewed publications during the last decade (2000 to 2009. Search criteria included all articles on relationships between any two of the above named factors. Although different methodological designs and variables were found as markers for the same factor, overall results suggested the existence of a clear positive relationship among physical activity, physical fitness, somatic fitness, and coordination from childhood to adolescence, with a special relevance for the relationship between physical activity and coordination. It was also noted a renewed interest on physical activity and motor coordination developmental characteristics and relationships as well as on their lifelong health effects.

  14. Travel Mode and Physical Activity at Sydney University

    Chris Rissel

    2013-08-01

    Full Text Available How staff and students travel to university can impact their physical activity level. An online survey of physical activity and travel behaviour was conducted in early November 2012 to inform planning of physical activity and active travel promotion programs at the University of Sydney, Australia as part of the “Sit Less, Move More” sub-committee of the Healthy University Initiative, and as baseline data for evaluation. There were 3,737 useable responses, 60% of which were from students. Four out of five respondents travelled to the University on the day of interest (Tuesday, November 30, 2012. The most frequently used travel modes were train (32%, car as driver (22%, bus (17%, walking (17% and cycling (6%. Staff were twice as likely to drive as students, and also slightly more likely to use active transport, defined as walking and cycling (26% versus 22%. Overall, 41% of respondents were sufficiently active (defined by meeting physical activity recommendations of 150 min per week. Participants were more likely to meet physical activity recommendations if they travelled actively to the University. With a high proportion of respondents using active travel modes or public transport already, increasing the physical activity levels and increasing the use of sustainable travel modes would mean a mode shift from public transport to walking and cycling for students is needed and a mode shift from driving to public transport or active travel for University staff. Strategies to achieve this are discussed.

  15. Physical Activity in the Mass Media: An Audience Perspective

    Smith, Ben J.; Bonfiglioli, Catriona M. F.

    2015-01-01

    Physical activity's role in promoting health is highlighted in public health campaigns, news and current affairs, reality television and other programs. An investigation of audience exposure, beliefs and reactions to media portrayals of physical activity offers insights into the salience and influence of this communication. An audience reception…

  16. School Culture and Physical Activity: A Systematic Review

    Rickwood, Greg

    2013-01-01

    This review examines literature on aspects of school culture and students' physical activity participation. The following questions were addressed: (1) what aspects of school culture have been examined in relation to physical activity, (2) what is the weight of evidence concerning the relationships between school culture factors and physical…

  17. Use of SPARK to Promote After-School Physical Activity

    Herrick, Heidi; Thompson, Hannah; Kinder, Jennifer; Madsen, Kristine A.

    2012-01-01

    Background: The after-school period is potentially an important venue for increasing physical activity for youth. We sought to assess the effectiveness of the Sports, Play, and Recreation for Youth (SPARK) program to increase physical activity and improve cardiorespiratory fitness and weight status among elementary students after school. Methods:…

  18. Determinants of Physical Activity in Middle School Children.

    Trost, Stewart G.; Saunders, Ruth; Ward, Dianne S.

    2002-01-01

    Evaluated the theory of reasoned action (TRA) and theory of planned behavior (TPB) in predicting moderate-to-vigorous physical activity (MVPA) in sixth grade students. Student surveys on physical activity behavior and attitudes and measurement of MVPA indicated that the TRA and TPB accounted for only a small percentage of the variance in MVPA. (SM)

  19. Relationship between physical activity and obesity in children and adolescents

    Guerra, S.; Teixeira-Pinto, A.; Ribeiro, J. C.;

    2006-01-01

    The purpose of the present study was to analyze the relationship between physical activity (PA) and obesity in Portuguese children and adolescents.......The purpose of the present study was to analyze the relationship between physical activity (PA) and obesity in Portuguese children and adolescents....

  20. Physical Activity, Metabolic Syndrome, and Overweight in Rural Youth

    Moore, Justin B.; Davis, Catherine L.; Baxter, Suzanne Domel; Lewis, Richard D.; Yin, Zenong

    2008-01-01

    Background: Research suggests significant health differences between rural dwelling youth and their urban counterparts with relation to cardiovascular risk factors. This study was conducted to (1) determine relationships between physical activity and markers of metabolic syndrome, and (2) to explore factors relating to physical activity in a…