WorldWideScience

Sample records for activity levels observed

  1. Activity in superior parietal cortex during training by observation predicts asymmetric learning levels across hands.

    Ossmy, Ori; Mukamel, Roy

    2016-01-01

    A dominant concept in motor cognition associates action observation with motor control. Previous studies have shown that passive action observation can result in significant performance gains in humans. Nevertheless, it is unclear whether the neural mechanism subserving such learning codes abstract aspects of the action (e.g. goal) or low level aspects such as effector identity. Eighteen healthy subjects learned to perform sequences of finger movements by passively observing right or left hand performing the same sequences in egocentric view. Using functional magnetic resonance imaging we show that during passive observation, activity in the superior parietal lobule (SPL) contralateral to the identity of the observed hand (right\\left), predicts subsequent performance gains in individual subjects. Behaviorally, left hand observation resulted in positively correlated performance gains of the two hands. Conversely right hand observation yielded negative correlation - individuals with high performance gains in one hand exhibited low gains in the other. Such behavioral asymmetry is reflected by activity in contralateral SPL during short-term training in the absence of overt physical practice and demonstrates the role of observed hand identity in learning. These results shed new light on the coding level in SPL and have implications for optimizing motor skill learning. PMID:27535179

  2. Ionospheric trough observation probability dependence on the season, local time, longitude and magnetic activity level

    Probability of different ionospheric trough observation for Kosmos satellite data (about 3000 circuits) is analysed. Trough appearance probability variations with the season, longitude, local time and magnetic activity are discriminated and investigated. It is shown that trough production probability depends on the magnetic activity and background ionization. The last is determined by illumination variations and neutral wind

  3. Features and amenities of school playgrounds: A direct observation study of utilization and physical activity levels outside of school time

    Swayampakala Kamala; Maslow Andréa L; Colabianchi Natalie

    2011-01-01

    Abstract Background A significant amount of research has examined whether park or playground availability is associated with physical activity. However, little research has examined whether specific features or amenities of parks or playgrounds, such as the number of unique types of playground equipment or the safety of the equipment is associated with utilization of the facility or physical activity levels while at the facility. There are no studies that use direct observation and a detailed...

  4. Direct observation of children’s preferences and activity levels during interactive and on-line electronic games

    McKenzie, TL; Sit, CHP; Lam, JWK

    2010-01-01

    BACKGROUND: Interactive electronic games have recently been popularized and are believed to help promote children's physical activity (PA). The purpose of the study was to examine preferences and PA levels during interactive and online electronic games among overweight and nonoverweight boys and girls. METHODS: Using a modification of the SOFIT, we systematically observed 70 Hong Kong Chinese children (35 boys, 35 girls; 50 nonoverweight, 20 overweight), age 9 to 12 years, during 2 60-minute ...

  5. Features and amenities of school playgrounds: A direct observation study of utilization and physical activity levels outside of school time

    Swayampakala Kamala

    2011-04-01

    Full Text Available Abstract Background A significant amount of research has examined whether park or playground availability is associated with physical activity. However, little research has examined whether specific features or amenities of parks or playgrounds, such as the number of unique types of playground equipment or the safety of the equipment is associated with utilization of the facility or physical activity levels while at the facility. There are no studies that use direct observation and a detailed park assessment to examine these associations. Methods Twenty urban schoolyards in the Midwest, ten of which were renovated, were included in this study. Using a detailed environmental assessment tool (i.e., Environmental Assessment of Public Recreation Spaces, information on a variety of playground attributes was collected. Using direct observation (i.e., System for Observing Play and Leisure Activity in Youth, the number of adults, girls and boys attending each schoolyard and their physical activity levels were recorded. Each schoolyard was observed ten times for 90 minutes each time outside of school hours. Clustered multivariable negative binomial regressions and linear regressions were completed to examine the association between playground attributes and utilization of the schoolyard and the proportion active on the playground, respectively. Effect modification by renovation status was also examined. Results At renovated schoolyards, the total number of play features was significantly associated with greater utilization in adults and girls; overall cleanliness was significantly associated with less utilization in girls and boys; and coverage/shade for resting features was significantly associated with greater utilization in adults and boys. At unrenovated schoolyards, overall safety was significantly associated with greater utilization in boys. No playground attribute was associated with the proportion active on the playground after adjusting for all

  6. Observation of Children's Physical Activity Levels in Primary School: Is the School an Ideal Setting for Meeting Government Activity Targets?

    Waring, Michael; Warburton, Peter; Coy, Martin

    2007-01-01

    Given the commitment (and funding) by the British government to promote physical activity among all ages, and despite the inevitable political manipulation of physical education (PE) and school sport, there is now an ideal opportunity to focus on primary schools as a key target group for the future. This study determined the physical activity…

  7. Dependence of the Sunspot-group Size on the Level of Solar Activity and its Influence on the Calibration of Solar Observers

    Usoskin, I G; Chatzistergos, T

    2016-01-01

    The distribution of the sunspot group size (area) and its dependence on the level of solar activity is studied. It is shown that the fraction of small groups is not constant but decreases with the level of solar activity so that high solar activity is largely defined by big groups. We study the possible influence of solar activity on the ability of a realistic observer to see and report the daily number of sunspot groups. It is shown that the relation between the number of sunspot groups as seen by different observers with different observational acuity thresholds is strongly non-linear and cannot be approximated by the traditionally used linear scaling ($k-$factors). The observational acuity threshold [$A_{\\rm th}$] is considered to quantify the quality of each observer, instead of the traditional relative $k-$factor. A nonlinear $c-$factor based on $A_{\\rm th}$ is proposed, which can be used to correct each observer to the reference conditions. The method is tested on a pair of principal solar observers, Wo...

  8. Activity-Level Externalities

    enrico, baffi

    2012-01-01

    In the literature we find unanimous consensus on the analysis of bilateral accident models. In bilateral accident models, indeed, it is usually held that both with the negligence rule and with strict liability with contributory negligence, the residual bearer adopts an efficient level of precaution and efficient activity levels; the party that is not the residual bearer, on the other hand, chooses an excessive activity level since once the due precautions have been taken, they do not answe...

  9. Dopamine D1 receptor activity is involved in the increased anxiety levels observed in STZ-induced diabetes in rats.

    Rebolledo-Solleiro, Daniela; Araiza, Luis Fernando Ontiveros; Broccoli, Laura; Hansson, Anita C; Rocha-Arrieta, Luisa Lilia; Aguilar-Roblero, Raúl; Crespo-Ramírez, Minerva; Fuxe, Kjell; Pérez de la Mora, Miguel

    2016-10-15

    Epidemiological surveys have indicated that anxiety disorders are more frequent in diabetic patients than in the general population. Similar results have been shown in animal studies using the streptozotocin (STZ)-induced diabetes model. The mechanisms underlying this relationship are not clearly understood, but it has been suggested that alterations in the dopaminergic neurotransmission, which plays an important role in the amygdaloid modulation of fear and anxiety, may be involved. The aim of this study was to ascertain whether or not the amygdaloid DA D1 receptors are involved in the increase of anxiety-like behavior observed in "diabetic" animals. Adult Wistar male rats were injected with STZ (50mg/kg, i.p.) in two consecutive days and subjected to the Shock-Probe Burying Test 10days after the beginning of treatment. STZ-treated rats showed a significant increase in immobility/freezing behavior whereas no effects were elicited in latency to bury, burying behavior itself and the number of shocks received during testing as compared with non-diabetic controls. These results suggest the triggering of a passive coping response in the STZ-treated rats. Interestingly, immobility/freezing behavior was reversed following the intra-amygdaloid dopamine D1 receptor blockade by the local microinfusion of SCH23390 (100ng/side). Autoradiographic experiments showed a selective increase of [(3)H]-SCH23390 binding in the ventral intercalated paracapsular islands of STZ-treated rats when compared to the non-treated control group. Our results suggest that a hyperdopaminergic state involving DA D1 receptors within the amygdala may have a role in the increase of anxiety observed in diabetic rats. PMID:27374159

  10. Global physical activity levels

    Hallal, Pedro C; Andersen, Lars Bo; Bull, Fiona C;

    2012-01-01

    To implement effective non-communicable disease prevention programmes, policy makers need data for physical activity levels and trends. In this report, we describe physical activity levels worldwide with data for adults (15 years or older) from 122 countries and for adolescents (13-15-years......-old) from 105 countries. Worldwide, 31·1% (95% CI 30·9-31·2) of adults are physically inactive, with proportions ranging from 17·0% (16·8-17·2) in southeast Asia to about 43% in the Americas and the eastern Mediterranean. Inactivity rises with age, is higher in women than in men, and is increased in high......-income countries. The proportion of 13-15-year-olds doing fewer than 60 min of physical activity of moderate to vigorous intensity per day is 80·3% (80·1-80·5); boys are more active than are girls. Continued improvement in monitoring of physical activity would help to guide development of policies and programmes...

  11. Observed confidence levels theory and application

    Polansky, Alan M

    2007-01-01

    Illustrating a simple, novel method for solving an array of statistical problems, Observed Confidence Levels: Theory and Application describes the basic development of observed confidence levels, a methodology that can be applied to a variety of common multiple testing problems in statistical inference. It focuses on the modern nonparametric framework of bootstrap-based estimates, allowing for substantial theoretical development and for relatively simple solutions to numerous interesting problems. After an introduction, the book develops the theory and application of observed confidence levels for general scalar parameters, vector parameters, and linear models. It then examines nonparametric problems often associated with smoothing methods, including nonparametric density estimation and regression. The author also describes applications in generalized linear models, classical nonparametric statistics, multivariate analysis, and survival analysis as well as compares the method of observed confidence levels to...

  12. Laboratory observation of quantum control level sets

    In controlled quantum dynamics, a level set is defined as the collection of control fields that produce a specific value for a particular observable. This paper explores the relationship between individual solutions to a control problem, and presents the first experimentally observed quantum control level sets, which are found to be continuous submanifolds. Level sets are observed for two photon transitions where the control is the spectral phase function, which is expressed as a fourth-order polynomial. For the systems studied here, the level sets are shown to be closed surfaces in the spectral phase control space. A perturbation analysis provides insight into the observed topology of the level set, which is shown to be preserved by the low-order polynomial phase representation. Each of the multiple control fields forming a level set preserves the observable value by its own distinct manipulation of constructive and destructive quantum interferences. Thus, the richness of quantum control fields meeting a particular observable value is accompanied by an equally diverse family of control mechanisms

  13. Soluble urokinase-type plasminogen activator receptor levels in patients with burn injuries and inhalation trauma requiring mechanical ventilation: an observational cohort study

    Backes, Yara; van der Sluijs, Koenraad F; Tuip de Boer, Anita M; Hofstra, Jorrit Jan; Vlaar, Alexander PJ; Determann, Rogier M; Knape, Paul; David P Mackie; Schultz, Marcus J.

    2011-01-01

    Introduction Soluble urokinase-type plasminogen activator receptor (suPAR) has been proposed as a biologic marker of fibrinolysis and inflammation. The aim of this study was to investigate the diagnostic and prognostic value of systemic and pulmonary levels of suPAR in burn patients with inhalation trauma who need mechanical ventilation. Methods suPAR was measured in plasma and nondirected lung-lavage fluid of mechanically ventilated burn patients with inhalation trauma. The samples were obta...

  14. [Observation of autoionization levels in uranium I].

    Jin, C; Wang, X

    1999-02-01

    A number of Rydberg and autoionization levels of U I have been studied using three-step resonant ionization methods with three pulsed tunable dye lasers. Energy levels of uranium atom have been measured, which were located in the 49898-50880 cm(-1) energy interval. PMID:15818900

  15. Wii mote as hydrological sensor: observation of water level fluctuations

    Luxemburg, W.; Hut, R.; Weijs, S.; Hegnauer, M.

    2009-12-01

    The input device of the Nintendo Wii, the Wii-mote offers scientist a multitude of cheap, high quality sensors; ideal for proof of concept testing. For a specific application, i.e. the water level fluctuation in a floating evaporation pan the Wii-mote was tested as the observing device. It is shown that the controller can observe movements with high enough temporal and spatial resolution of up to 4 infrared LED’s to describe water level movements. Floating pans positioned in lakes and reservoirs better represent open water evaporation than evaporation pans installed on land. On the other hand performing water level measurements in a floating pan is more complicated due to movement of the pan and wave activities in the pan. The Wii-mote was mounted on the side of a standard class A-pan and a float was placed in the middle of the pan, with 4 LED’s on top moving along a fixed bar. The information that the Wii-mote wirelessly sends by blue tooth was captured on a laptop. With a MATLAB routine this data was converted into movement of the LED’s relatively to the controller. The observations show that wave activities are nicely captured with a typical spatial resolution smaller than 0.1 mm in our set-up and a temporal resolution of maximum 100 Hz. A frequency domain filter was applied to the observed datasets to obtain average water levels. In our laboratory setting the pan was placed in a large basin with a wave generator. A constant, but small, rate of water was added to the evaporation pan. The average pan levels from the filtered datasets showed systematically lower levels compared to the level without any wave activities. This is a typical effect of waves that occur in shallow basins. However, the added water with rates up to 5 mm/hour were clearly recognized in the filtered datasets which indicates that the Wii-mote is very well capable as a sensor for water level observations.

  16. Observations: Oceanic climate change and sea level

    Bindoff, N.L.; Willebrand, J.; Artale, V.; Cazenave, A.; Gregory, J.; Gulev, S.; Hanawa, K.; LeQuere, C.; Levitus, S.; Nojiri, Y.; Shum, C.K.; Talley, L.D.; Unnikrishnan, A.S.

    of ocean salinity cause the ocean to expand or contract and hence change the sea level both regionally and globally. The ocean varies over a broad range of time scales, from seasonal (e.g., in the surface mixed layer) to decadal (e.g., circulation... Change Climate Change 2007 The Physical Science Basis CAMBRIDGE UNIVERSITY PRESS Cambridge, New York, Melbourne, Madrid, Cape Town, Singapore, São Paolo, Delhi Cambridge University Press 32 Avenue of the Americas, New York, NY 10013-2473, USA www...

  17. Variations observed in environmental radiation at ground level

    To investigate and monitor environmental radiation at ground level, Physikalisch-Technische Bundesanstalt (PTB) has installed several dosemeters and particle detectors at the new Ambient Radiation Dosimetry Site. The separation of the total ambient dose equivalent rate H*(10)env of environmental radiation into the different contributions is achieved by comparing the data of different detectors: the muon detector MUDOS, a modified neutron dosemeter, proportional counters and ionisation chambers. The response of the latter two dosemeter systems to cosmic radiation was determined at the Cosmic Radiation Dosimetry Site on a lake near PTB. Besides the increase of the ambient dose equivalent rate during rainfall, variations owing to air pressure, solar activity and temperature changes in the upper atmosphere are observed. Without rain and solar effects, smooth variations of the cosmic component at ground level of ±6.9 nSv h-1 should be treated as naturally occurring variations during an entire year. (authors)

  18. 3-D reconstructions of active stars - observations

    Korhonen, Heidi

    2012-01-01

    Stars are usually faint point sources and investigating their surfaces and interiors observationally is very demanding. Here I give a review on the state-of-the-art observing techniques and recent results on studying interiors and surface features of active stars.

  19. CORAL: model for no observed adverse effect level (NOAEL).

    Toropov, Andrey A; Toropova, Alla P; Pizzo, Fabiola; Lombardo, Anna; Gadaleta, Domenico; Benfenati, Emilio

    2015-08-01

    The in vivo repeated dose toxicity (RDT) test is intended to provide information on the possible risk caused by repeated exposure to a substance over a limited period of time. The measure of the RDT is the no observed adverse effect level (NOAEL) that is the dose at which no effects are observed, i.e., this endpoint indicates the safety level for a substance. The need to replace in vivo tests, as required by some European Regulations (registration, evaluation authorization and restriction of chemicals) is leading to the searching for reliable alternative methods such as quantitative structure-activity relationships (QSAR). Considering the complexity of the RDT endpoint, for which data quality is limited and depends anyway on the study design, the development of QSAR for this endpoint is an attractive task. Starting from a dataset of 140 organic compounds with NOAEL values related to oral short term toxicity in rats, we developed a QSAR model based on optimal descriptors calculated with simplified molecular input-line entry systems and the graph of atomic orbitals by the Monte Carlo method, using CORAL software. Three different splits into the training, calibration, and validation sets are studied. The mechanistic interpretation of these models in terms of molecular fragment with positive or negative contributions to the endpoint is discussed. The probabilistic definition for the domain of applicability is suggested. PMID:25850638

  20. The Built Environment Predicts Observed Physical Activity

    Kelly, Cheryl; Wilson, Jeffrey S.; Schootman, Mario; Clennin, Morgan; Baker, Elizabeth A.; Miller, Douglas K.

    2014-01-01

    Background: In order to improve our understanding of the relationship between the built environment and physical activity, it is important to identify associations between specific geographic characteristics and physical activity behaviors. Purpose: Examine relationships between observed physical activity behavior and measures of the built environment collected on 291 street segments in Indianapolis and St. Louis. Methods: Street segments were selected using a stratified geographic samp...

  1. Birth Order and Activity Level in Children.

    Eaton, Warren O.; And Others

    1989-01-01

    Studied 7,018 children between birth and 7 years and 81 children of 5-8 years to test the hypothesis that birth order is negatively related to motor activity level. Activity level declined linearly across birth position, so that early-borns were rated as more active than later-borns. (RJC)

  2. Present day sea level changes: observation and causes

    Whereas sea level has changed little over the last 2000 years, it has risen at a rate of about 2 mm/year during the 20. century. This unexpected sea level rise has been attributed to the anthropogenic global warming, recorded over several decades. Sea level variations have been measured globally and precisely for about 12 years due to satellite altimeter missions Topex/Poseidon and Jason-1. These observations indicate a global mean sea level rise of about 3 mm/year since 1993, a value significantly larger than observed during previous decades. Recent observations have allowed us to quantify the various climatic factors contributing to observed sea level change: thermal expansion of sea water due to ocean warming, melting of mountain glaciers and ice sheets, and changes in the land water reservoirs. A water budget based on these new observations allows us to partly explain the observed sea level rise. In particular, we show that the thermal expansion explains only 25% of the secular sea level rise as recorded by tide-gauges over the last 50 years, while it contributes about 50% of sea level rise observed over the last decade. Meanwhile, recent studies show that glacier and ice sheet melting could contribute the equivalent of 1 mm/year in sea level rise over the last decade. In addition, the high regional variability of sea level trends revealed by satellite altimetry is mainly due to thermal expansion. There is also an important decadal spatio-temporal variability in the ocean thermal expansion over the last 50 years, which seems to be controlled by natural climate fluctuations. We question for the first time the link between the decadal fluctuations in the ocean thermal expansion and in the land reservoirs, and indeed their climatic contribution to sea level change. Finally a preliminary analysis of GRACE spatial gravimetric observations over the oceans allows us to estimate the seasonal variations in mean sea level due to ocean water mass balance variations

  3. Linking Diverse Levels of Activity

    Sørensen, Brian Vejrum; Boer, Harry

    2006-01-01

    /or knowledge intensive companies (Starbuck 1992), which, due to their unsettled form and process, rely on the sense their members make of the change inputs and their creative enactment of these inputs. In such companies, change is a part of everyday practice that (re)produces organisational configurations and......Organisations start strategic renewal initiatives more often than ever before. Many initiatives, however, have little practical effect on the practices they are meant to change. They do not seem to submerge to the level where they become part of the actionable knowledge of the organisation....... Furthermore, the implementation of strategic organisational change, even if based on good arguments, solid analysis and the best intentions, tends to be fraught with unintended consequences. In this paper we aim to supply an explanation for this, based on a longitudinal study, and grounded in a social...

  4. The future for the Global Sea Level Observing System (GLOSS) Sea Level Data Rescue

    Bradshaw, Elizabeth; Matthews, Andrew; Rickards, Lesley; Aarup, Thorkild

    2016-04-01

    Historical sea level data are rare and unrepeatable measurements with a number of applications in climate studies (sea level rise), oceanography (ocean currents, tides, surges), geodesy (national datum), geophysics and geology (coastal land movements) and other disciplines. However, long-term time series are concentrated in the northern hemisphere and there are no records at the Permanent Service for Mean Sea Level (PSMSL) global data bank longer than 100 years in the Arctic, Africa, South America or Antarctica. Data archaeology activities will help fill in the gaps in the global dataset and improve global sea level reconstruction. The Global Sea Level Observing System (GLOSS) is an international programme conducted under the auspices of the WMO-IOC Joint Technical Commission for Oceanography and Marine Meteorology. It was set up in 1985 to collect long-term tide gauge observations and to develop systems and standards "for ocean monitoring and flood warning purposes". At the GLOSS-GE-XIV Meeting in 2015, GLOSS agreed on a number of action items to be developed in the next two years. These were: 1. To explore mareogram digitisation applications, including NUNIEAU (more information available at: http://www.mediterranee.cerema.fr/logiciel-de-numerisation-des-enregistrements-r57.html) and other recent developments in scanning/digitisation software, such as IEDRO's Weather Wizards program, to see if they could be used via a browser. 2. To publicise sea level data archaeology and rescue by: • maintaining and regularly updating the Sea Level Data Archaeology page on the GLOSS website • strengthening links to the GLOSS data centres and data rescue organisations e.g. linking to IEDRO, ACRE, RDA • restarting the sea level data rescue blog with monthly posts. 3. Investigate sources of funding for data archaeology and rescue projects. 4. Propose "Guidelines" for rescuing sea level data. These action items will aid the discovery, scanning, digitising and quality control

  5. Observational Study of Solar Magnetic Active Phenomena

    Hongqi Zhang

    2006-06-01

    The electric current separated into two parts reflected the quantative properties of heterogeneity and chirality of magnetic field, and defined them as the shear and twist components of current. We analyze the basic configuration and evolution of superactive region NOAA 6580-6619-6659. It is found that the contribution of the twist component of current cannot be reflected in the normal analysis of the magnetic shear and gradient of the active regions. The observational evidence of kink magnetic ropes generated from the subatmosphere cannot be found completely in some super delta active regions.

  6. Dynamic Observation of Interlukin 17 Levels in AIDS Patients Received Highly Active Antiretroviral Therapy%白细胞介素17在接受抗病毒治疗的艾滋病人中的动态观察

    李鎏勋; 郑力文; 郑煜煌; 李靖; 何艳

    2011-01-01

    Objective To observe the dynamic changes of interlukin 17 (IL-17) in HIV/AIDS patients with or without highly active antiretrovival therapy (HAART). Methods Peripheral blood samples were collected from 30 normal volunteers and 33 HIV/AIDS patients received HAART. ELISA was used to determine IL -17 levels in sera and the results were compared. At the time points of ore - therapy, 6th month and 12th month of therapy, IL - 17 levels in sera were tested by ELISA, and the dynamic changes of IL -17 levels were compared and analyzed. The flow cytometer was used to count CD4* T- cells and quantitative real-time RT-PCR was used to determine HIV RNA in blood. Results The levels of IL-17 in HIV/AIDS patients at the time points of pre - therapy, 6th month and 12th month of therapy and in the normal volunteers were (5.3±2.5) pg/ml, (7.7±2.4) pg/ml, (10.4±3.1) pg/ml and (17.7±6.6) pg/ml, respectively. The levels of IL -17 were positively correlated with CO4+ T - cell counts, but negatively correlated with HIV viral load. Conclusions The results indicate that IL-17 may play an important role in the pathogenesis of AIDS, and likely to be one of the effective indexes for observing AIDS progress and efficacy of HAART.%目的 观察HIV感染者和AIDS患者(HIV/AIDS)的血清白细胞介素-17(IL-17)水平与正常入水平的区别,及其在接受抗病毒治疗一年中的动态变化. 方法 采集33例HIV/AIDS和30例健康志愿者的静脉血清,以酶联免疫吸附法(ELISA)分别检测其IL- 17水平并对比分析,并在33例HIV/AIDS接受高效抗反转录病毒治疗(HAART)的0、6、12月时分别采集静脉血,同法检测血清IL- 17动态水平并对比分析.以流式细胞计数法检测CD4+细胞数,以real- time RT - PCR法定量检测HIVRNA. 结果 HIV/AIDS在接受HAART治疗前、治疗6月、12月及正常人静脉血IL- 17水平分别为(5.3±2.5)、(7.7±2.4)、(10.4±3.1)和(17.7±6.60)pg/ml; IL-17水平与CD4+T细胞计数正

  7. Observations. Oceanic Climate Change and Sea Level. Chapter 5

    Bindoff, N.L.; Willebrand, J.; Artale, V.; Cazenave, A.; Gregory, J.; Gulev, S.; Hanawa, K.; Le Quere, C.; Levitus, S.; Nojiri, Y.; Shum, C.K.; Talley, L.D.; Unnikrishnan, A.

    2007-09-15

    The ocean has an important role in climate variability and change. The ocean's heat capacity is about 1,000 times larger than that of the atmosphere, and the oceans net heat uptake since 1960 is around 20 times greater than that of the atmosphere. This large amount of heat, which has been mainly stored in the upper layers of the ocean, plays a crucial role in climate change, in particular variations on seasonal to decadal time scales. The transport of heat and freshwater by ocean currents can have an important effect on regional climates, and the large-scale Meridional Overturning Circulation (MOC; also referred to as thermohaline circulation) influences the climate on a global scale. Life in the sea is dependent on the biogeochemical status of the ocean and is influenced by changes in the physical state and circulation. Changes in ocean biogeochemistry can directly feed back to the climate system, for example, through changes in the uptake or release of radiatively active gases such as carbon dioxide. Changes in sea level are also important for human society, and are linked to changes in ocean circulation. Finally, oceanic parameters can be useful for detecting climate change, in particular temperature and salinity changes in the deeper layers and in different regions where the short-term variability is smaller and the signal-to-noise ratio is higher. The large-scale, three-dimensional ocean circulation and the formation of water masses that ventilate the main thermocline together create pathways for the transport of heat, freshwater and dissolved gases such as carbon dioxide from the surface ocean into the density-stratified deeper ocean, thereby isolating them from further interaction with the atmosphere. These pathways are also important for the transport of anomalies in these parameters caused by changes in the surface conditions. Furthermore, changes in the storage of heat and in the distribution of ocean salinity cause the ocean to expand or contract

  8. Suzaku observations of 'bare' active galactic nuclei

    Walton, D J; Fabian, A C; Gallo, L C; Reis, R C

    2012-01-01

    We present a X-ray spectral analysis of a large sample of 25 'bare' active galactic nuclei, sources with little or no complicating intrinsic absorption, observed with Suzaku. Our work focuses on studying the potential contribution from relativistic disc reflection, and examining the implications of this interpretation for the intrinsic spectral complexities frequently displayed by AGN in the X-ray bandpass. During the analysis, we take the unique approach of attempting to simultaneously undertake a systematic analysis of the whole sample, as well as a detailed treatment of each individual source, and find that disc reflection has the required flexibility to successfully reproduce the broadband spectrum observed for all of the sources considered. Where possible, we use the reflected emission to place constraints on the black hole spin for this sample of sources. Our analysis suggests a general preference for rapidly rotating black holes, which if taken at face value is most consistent with the scenario in whic...

  9. Sea level data archaeology and the Global Sea Level Observing System (GLOSS)

    Elizabeth Bradshaw; Lesley Rickards; Thorkild Aarup

    2015-01-01

    The Global Sea Level Observing System (GLOSS) Group of Experts (GE) data archaeology group is collating tools and producing guidelines for historic sea level data. They aim to aid the discovery, scanning, digitising and quality control of analogue tide gauge charts and sea level ledgers. Their goal is to improve the quality, quantity and availability of long-term sea level data series. This paper examines different tools for the automatic digitisation of tide gauge charts, the methods availab...

  10. MESSENGER Observations of Substorm Activity at Mercury

    Sun, W. J.; Slavin, J. A.; Fu, S.; Raines, J. M.; Zong, Q. G.; Poh, G.; Jia, X.; Sundberg, T.; Gershman, D. J.; Pu, Z.; Zurbuchen, T.; Shi, Q.

    2015-12-01

    MErcury Surface, Space ENviroment, GEochemistry, and Ranging (MESSENGER) magnetic field and plasma measurements taken during crossings of Mercury's magnetotail from 2011 to 2014 have been investigated for substorms. A number of events with clear Earth-like growth phase and expansion phase signatures were found. The thinning of the plasma sheet and the increase of magnetic field intensity in the lobe were observed during the growth phase and plasma sheet was observed to thicken during the expansion phase, which are similar to the observations at Earth. But the time scale of Mercury's substorm is only several minutes comparing with the several hours at Earth [Sun et al., 2015a]. Detailed analysis of magnetic field fluctuations during the substorm expansion phase have revealed low frequency plasma waves, e.g. Pi2-like pulsations. The By fluctuations accompanying substorm dipolarizations are consistent with pulses of field-aligned currents near the high latitude edge of the plasma sheet. Further study shows that they are near-circularly polarized electromagnetic waves, most likely Alfvén waves. Soon afterwards the plasma sheet thickened and MESSENGER detected a series of compressional waves. We have also discussed their possible sources [Sun et al., 2015b]. Sun, W.-J., J. A. Slavin, S. Y. Fu, et al. (2015a), MESSENGER observations of magnetospheric substorm activity in Mercury's near magnetotail. Geophys. Res. Lett., 42, 3692-3699. doi: 10.1002/2015GL064052.Sun, W.-J., J. A. Slavin, S. Y. Fu, et al. (2015b), MESSENGER observations of Alfvénic and compressional waves during Mercury's substorms. Geophys. Res. Lett., 42, in press. doi: 10.1002/ 2015GL065452.

  11. Measuring progress of the global sea level observing system

    Woodworth, Philip L.; Aarup, Thorkild; Merrifield, Mark; Mitchum, Gary T.; Le Provost, Christian

    Sea level is such a fundamental parameter in the sciences of oceanography geophysics, and climate change, that in the mid-1980s, the Intergovernmental Oceanographic Commission (IOC) established the Global Sea Level Observing System (GLOSS). GLOSS was to improve the quantity and quality of data provided to the Permanent Service for Mean Sea Level (PSMSL), and thereby, data for input to studies of long-term sea level change by the Intergovernmental Panel on Climate Change (IPCC). It would also provide the key data needed for international programs, such as the World Ocean Circulation Experiment (WOCE) and later, the Climate Variability and Predictability Programme (CLIVAR).GLOSS is now one of the main observation components of the Joint Technical Commission for Oceanography and Marine Meteorology (JCOMM) of IOC and the World Meteorological Organization (WMO). Progress and deficiencies in GLOSS were presented in July to the 22nd IOC Assembly at UNESCO in Paris and are contained in the GLOSS Assessment Report (GAR) [IOC, 2003a].

  12. Observation of Low Level Heating in an Erupting Prominence

    Kucera, Therese A.

    2007-01-01

    We present multi-wavelength observations of low level heating in an erupting prominence observed in the UV and EUV over a wide range of temperatures and wavelengths by SOHO's SUMER instrument, TRACE and also in H-alpha by the Yunnan Astronomical Observatory. The eruption occurred on 2004 April 30. The heating is relatively mild, leading only to the ionization of neutral hydrogen and probably helium. It is also localized, occurring along the bottom edge of the erupting prominence and in a kink-like feature in the prominence. The heating is revealed as a decrease in the Lyman absorption. This decrease results in an apparent increase in emission in all the lines observed by SUMER, especially those formed at temperatures -1 0A5. However, this is due to the disappearance of cooler absorbing material in the prominence rather than an increase in these higher temperature species.

  13. Sea Level Data Archaeology for the Global Sea Level Observing System (GLOSS)

    Bradshaw, Elizabeth; Matthews, Andy; Rickards, Lesley; Jevrejeva, Svetlana

    2015-04-01

    The Global Sea Level Observing System (GLOSS) was set up in 1985 to collect long term tide gauge observations and has carried out a number of data archaeology activities over the past decade, including sending member organisations questionnaires to report on their repositories. The GLOSS Group of Experts (GLOSS GE) is looking to future developments in sea level data archaeology and will provide its user community with guidance on finding, digitising, quality controlling and distributing historic records. Many records may not be held in organisational archives and may instead by in national libraries, archives and other collections. GLOSS will promote a Citizen Science approach to discovering long term records by providing tools for volunteers to report data. Tide gauge data come in two different formats, charts and hand-written ledgers. Charts are paper analogue records generated by the mechanical instrument driving a pen trace. Several GLOSS members have developed software to automatically digitise these charts and the various methods were reported in a paper on automated techniques for the digitization of archived mareograms, delivered to the GLOSS GE 13th meeting. GLOSS is creating a repository of software for scanning analogue charts. NUNIEAU is the only publically available software for digitising tide gauge charts but other organisations have developed their own tide gauge digitising software that is available internally. There are several other freely available software packages that convert image data to numerical values. GLOSS could coordinate a comparison study of the various different digitising software programs by: Sending the same charts to each organisation and asking everyone to digitise them using their own procedures Comparing the digitised data Providing recommendations to the GLOSS community The other major form of analogue sea level data is handwritten ledgers, which are usually observations of high and low waters, but sometimes contain higher

  14. Sea level changes along the Indian coast: Observations and projections

    Unnikrishnan, A.S.; Kumar, K.R.; Fernandes, S.E.; Michael, G.S.; Patwardhan, S.K.

    : CLIMATE CHANGE AND INDIA CURRE NT SCIENCE, VOL. 90, NO. 3, 10 FEBRUARY 2006 *For correspondence. (e - mail: unni@darya.nio.org ) Sea level changes along the Indian coast: Observ a tions and projections A. S. Unnikrishnan 1, *, K. Rupa Kumar... with the occu r rence of tropical cyclones in the Bay of Bengal and associated storm surges in a future climate scenario. Projections for the future are needed for decision making by planners and policy makers. Future pr o jecti ons are made for different...

  15. Extraction of Children's Friendship Relation from Activity Level

    Kono, Aki; Shintani, Kimio; Katsuki, Takuya; Kihara, Shin'ya; Ueda, Mari; Kaneda, Shigeo; Haga, Hirohide

    Children learn to fit into society through living in a group, and it's greatly influenced by their friend relations. Although preschool teachers need to observe them to assist in the growth of children's social progress and support the development each child's personality, only experienced teachers can watch over children while providing high-quality guidance. To resolve the problem, this paper proposes a mathematical and objective method that assists teachers with observation. It uses numerical data of activity level recorded by pedometers, and we make tree diagram called dendrogram based on hierarchical clustering with recorded activity level. Also, we calculate children's ``breadth'' and ``depth'' of friend relations by using more than one dendrogram. When we record children's activity level in a certain kindergarten for two months and evaluated the proposed method, the results usually coincide with remarks of teachers about the children.

  16. Observational evidence for enhanced magnetic activity of superflare stars.

    Karoff, Christoffer; Knudsen, Mads Faurschou; De Cat, Peter; Bonanno, Alfio; Fogtmann-Schulz, Alexandra; Fu, Jianning; Frasca, Antonio; Inceoglu, Fadil; Olsen, Jesper; Zhang, Yong; Hou, Yonghui; Wang, Yuefei; Shi, Jianrong; Zhang, Wei

    2016-01-01

    Superflares are large explosive events on stellar surfaces one to six orders-of-magnitude larger than the largest flares observed on the Sun throughout the space age. Due to the huge amount of energy released in these superflares, it has been speculated if the underlying mechanism is the same as for solar flares, which are caused by magnetic reconnection in the solar corona. Here, we analyse observations made with the LAMOST telescope of 5,648 solar-like stars, including 48 superflare stars. These observations show that superflare stars are generally characterized by larger chromospheric emissions than other stars, including the Sun. However, superflare stars with activity levels lower than, or comparable to, the Sun do exist, suggesting that solar flares and superflares most likely share the same origin. The very large ensemble of solar-like stars included in this study enables detailed and robust estimates of the relation between chromospheric activity and the occurrence of superflares. PMID:27009381

  17. Are Preschool Children Active Enough? Objectively Measured Physical Activity Levels

    Cardon, Greet M.; De Bourdeaudhuij, Ilse M. M.

    2008-01-01

    The present study aimed to describe accelerometer-based physical activity levels in 4- and 5-year-old children (N = 76) on 2 weekdays and 2 weekend days. The children were sedentary for 9.6 hr (85%) daily, while they engaged in moderate to vigorous physical activity (MVPA) for 34 min (5%). Only 7% of the children engaged in MVPA for 60 min per…

  18. 12 Years of Stellar Activity Observations in Argentina

    Mauas, Pablo J D; Diaz, R; Vieytes, M; Petrucci, R; Jofre, E; Abrevaya, X; Luoni, M L; Valenzuela, P

    2012-01-01

    We present an observational program we started in 1999, to systematically obtain mid-resolution spectra of late-type stars, to study in particular chromospheric activity. In particular, we found cyclic activity in four dM stars, including Prox-Cen. We directly derived the conversion factor that translates the known S index to flux in the Ca II cores, and extend its calibration to a wider spectral range. We investigated the relation between the activity measurements in the calcium and hydrogen lines, and found that the usual correlation observed is the product of the dependence of each flux on stellar color, and it is not always preserved when simultaneous observations of a particular star are considered. We also used our observations to model the chromospheres of stars of different spectral types and activity levels, and found that the integrated chromospheric radiative losses, normalized to the surface luminosity, show a unique trend for G and K dwarfs when plotted against the S index.

  19. Play Equipment, Physical Activity Opportunities, and Children's Activity Levels at Childcare

    Jessica S. Gubbels

    2012-01-01

    Full Text Available This study investigated the association between physical activity facilities at childcare (e.g., play equipment and physical activity of 2- and 3-year olds. Observations of physical activity intensity were performed among 175 children at 9 childcare centers in The Netherlands, using the OSRAC-P. The physical activity facilities were assessed for indoors and outdoors separately, using the EPAO instrument. Regular (single-level multivariate and multilevel linear regression analyses examined the association of the facilities and child characteristics (age and sex with children's activity levels. Various physical activity facilities were available in all childcare centers (e.g., balls. Riding toys and a small playing area were associated with lower indoor physical activity levels. Outdoor physical activity levels were positively associated with the availability of portable jumping equipment and the presence of a structured track on the playground. Portable slides, fixed swinging equipment, and sandboxes were negatively associated with outdoor activity levels. In addition, the 3-year old children were more active outdoors than the 2-year olds. In conclusion, not all physical activity facilities at childcare were indeed positively associated with children's activity levels. The current findings provide concrete leads for childcare providers regarding which factors they can improve in the physical environment to facilitate children's physical activity.

  20. Play Equipment, Physical Activity Opportunities, and Children's Activity Levels at Childcare

    Gubbels, Jessica S; Van Kann, Dave H. H.; Jansen, Maria W J

    2012-01-01

    This study investigated the association between physical activity facilities at childcare (e.g., play equipment) and physical activity of 2- and 3-year olds. Observations of physical activity intensity were performed among 175 children at 9 childcare centers in The Netherlands, using the OSRAC-P. The physical activity facilities were assessed for indoors and outdoors separately, using the EPAO instrument. Regular (single-level) multivariate and multilevel linear regression analyses examined t...

  1. OBSERVING CORONAL NANOFLARES IN ACTIVE REGION MOSS

    The High-resolution Coronal Imager (Hi-C) has provided Fe XII 193Å images of the upper transition region moss at an unprecedented spatial (∼0.''3-0.''4) and temporal (5.5 s) resolution. The Hi-C observations show in some moss regions variability on timescales down to ∼15 s, significantly shorter than the minute-scale variability typically found in previous observations of moss, therefore challenging the conclusion of moss being heated in a mostly steady manner. These rapid variability moss regions are located at the footpoints of bright hot coronal loops observed by the Solar Dynamics Observatory/Atmospheric Imaging Assembly in the 94 Å channel, and by the Hinode/X-Ray Telescope. The configuration of these loops is highly dynamic, and suggestive of slipping reconnection. We interpret these events as signatures of heating events associated with reconnection occurring in the overlying hot coronal loops, i.e., coronal nanoflares. We estimate the order of magnitude of the energy in these events to be of at least a few 1023 erg, also supporting the nanoflare scenario. These Hi-C observations suggest that future observations at comparable high spatial and temporal resolution, with more extensive temperature coverage, are required to determine the exact characteristics of the heating mechanism(s).

  2. General considerations about the tritium activity levels observed in France and about the sampling and measurement techniques used by IRSN in the framework of the environment monitoring of the 2M Process site at Saint-Maur-des-Fosses

    A building of 2M Process company at Saint-Maur-des-Fosses (France) has been accidentally contaminated after the handling of a tritium contaminated device. The consequence has been a tritium release inside and in the close environment of the building. Since November 5, on request of the French nuclear safety authority (ASN), the French institute of radiation protection and nuclear safety (IRSN) has performed tritium measurements in water, air and plants sampled in the vicinity of the building in order to delimit the contaminated area and to follow its decay during and after the cleansing of the building. In order to give help to the interpretation of the results of this monitoring action, this note supplies some general information about tritium and its activity levels usually encountered in France (air, rainwater, surface waters, plants, drinking water, foodstuff), and about the sampling and measurement techniques used by IRSN in the framework of the periodical environment monitoring of the 2M Process site. (J.S.)

  3. Active Latitude Oscillations Observed on the Sun

    Kilcik, A.; Yurchyshyn, V.; Clette, F.; Ozguc, A.; Rozelot, J.-P.

    2016-04-01

    We investigate periodicities in the mean heliographic latitudes of sunspot groups, called active latitudes, for the past six complete solar cycles (1945 - 2008). For this purpose, the multitaper method and Morlet wavelet analysis were used. We found that solar rotation periodicities (26 - 38 days) are present in active latitudes of both hemispheres for all the investigated cycles (18 to 23). Both in the northern and southern hemispheres, active latitudes drifted toward the equator from the beginning to the end of each cycle and followed an oscillating path. These motions are well described by a second-order polynomial. There are no meaningful periods of between 55 and about 300 days in either hemisphere for all cycles. A periodicity of 300 to 370 days appears in both hemispheres for Cycle 23, in the northern hemisphere for Cycle 20, and in the southern hemisphere for Cycle 18.

  4. Active Latitude Oscillations Observed on the Sun

    Kilcik, A; Clette, F; Ozguc, A; Rozelot, J -P

    2016-01-01

    We investigate periodicities in mean heliographic latitudes of sunspot groups, called active latitudes, for the last six complete solar cycles (1945-2008). For this purpose, the Multi Taper Method and Morlet Wavelet analysis methods were used. We found the following: 1) Solar rotation periodicities (26-38 days) are present in active latitudes of both hemispheres for all the investigated cycles (18 to 23). 2) Both in the northern and southern hemispheres, active latitudes drifted towards the equator starting from the beginning to the end of each cycle by following an oscillating path. These motions are well described by a second order polynomial. 3) There are no meaningful periods between 55 and about 300 days in either hemisphere for all cycles. 4) A 300 to 370 day periodicity appears in both hemispheres for Cycle 23, in the northern hemisphere for Cycle 20, and in the southern hemisphere for Cycle 18.

  5. Observing coronal nanoflares in active region moss

    Testa, Paola; Martinez-Sykora, Juan; DeLuca, Ed; Hansteen, Viggo; Cirtain, Jonathan; Winebarger, Amy; Golub, Leon; Kobayashi, Ken; Korreck, Kelly; Kuzin, Sergey; Walsh, Robert; DeForest, Craig; Title, Alan; Weber, Mark

    2013-01-01

    The High-resolution Coronal Imager (Hi-C) has provided Fe XII 193A images of the upper transition region moss at an unprecedented spatial (~0.3-0.4 arcsec) and temporal (5.5s) resolution. The Hi-C observations show in some moss regions variability on timescales down to ~15s, significantly shorter than the minute scale variability typically found in previous observations of moss, therefore challenging the conclusion of moss being heated in a mostly steady manner. These rapid variability moss regions are located at the footpoints of bright hot coronal loops observed by SDO/AIA in the 94A channel, and by Hinode/XRT. The configuration of these loops is highly dynamic, and suggestive of slipping reconnection. We interpret these events as signatures of heating events associated with reconnection occurring in the overlying hot coronal loops, i.e., coronal nanoflares. We estimate the order of magnitude of the energy in these events to be of at least a few $10^{23}rg, also supporting the nanoflare scenario. These Hi-C...

  6. Development and Testing of the Observational System for Recording Physical Activity in Children: Elementary School

    McIver, Kerry L.; Brown, William H.; Pfeiffer, Karin A.; Dowda, Marsha; Pate, Russell R.

    2016-01-01

    Purpose: This study describes the development and pilot testing of the Observational System for Recording Physical Activity-Elementary School (OSRAC-E) Version. Method: This system was developed to observe and document the levels and types of physical activity and physical and social contexts of physical activity in elementary school students…

  7. Serum Renalase Levels Correlate with Disease Activity in Lupus Nephritis.

    Chaojun Qi

    Full Text Available Lupus nephritis (LN is among the most serious complications of systemic lupus erythematosus (SLE, which causes significant morbidity and mortality. Renalase is a novel, kidney-secreted cytokine-like protein that promotes cell survival. Here, we aimed to investigate the relationship of serum renalase levels with LN and its role in the disease progression of LN.For this cross-sectional study, 67 LN patients and 35 healthy controls were enrolled. Seventeen active LN patients who received standard therapies were followed up for six months. Disease activity was determined by the SLE Disease Activity-2000 (SLEDAI-2K scoring system and serum renalase amounts were determined by ELISA. Predictive value of renalase for disease activity was assessed. Furthermore, the expression of renalase in the kidneys of patients and macrophage infiltration was assessed by immunohistochemistry.Serum renalase amounts were significantly higher in LN patients than in healthy controls. Moreover, patients with proliferative LN had more elevated serum renalase levels than Class V LN patients. In proliferative LN patients, serum renalase levels were significantly higher in patients with active LN than those with inactive LN. Serum renalase levels were positively correlated with SLEDAI-2K, 24-h urine protein excretion, ds-DNA and ESR but inversely correlated with serum albumin and C3. Renalase amounts decreased significantly after six-months of standard therapy. The performance of renalase as a marker for diagnosis of active LN was 0.906 with a cutoff value of 66.67 μg/ml. We also observed that the amount of renalase was significantly higher in glomerular of proliferative LN along with the co-expression of macrophages.Serum renalase levels were correlated with disease activity in LN. Serum renalase might serve as a potential indicator for disease activity in LN. The marked increase of glomerular renalase and its association with macrophages suggest that it might play an

  8. Multi-wavelength Observations of Solar Active Region NOAA 7154

    Bruner, M. E.; Nitta, N. V.; Frank. Z. A.; Dame, L.; Suematsu, Y.

    2000-01-01

    We report on observations of a solar active region in May 1992 by the Solar Plasma Diagnostic Experiment (SPDE) in coordination with the Yohkoh satellite (producing soft X-ray images) and ground-based observatories (producing photospheric magnetograms and various filtergrams including those at the CN 3883 A line). The main focus is a study of the physical conditions of hot (T is approximately greater than 3 MK) coronal loops at their foot-points. The coronal part of the loops is fuzzy but what appear to be their footpoints in the transition region down to the photosphere are compact. Despite the morphological similarities, the footpoint emission at 10(exp 5) K is not quantitatively correlated with that at approximately 300 km above the tau (sub 5000) = 1 level, suggesting that the heat transport and therefore magnetic field topology in the intermediate layer is complicated. High resolution imaging observations with continuous temperature coverage are crucially needed.

  9. Rotational modes contribution to the observed level density

    Attempt is made to apply the level density systematics within the framework of the generalized superfluid model to the A<150 region. The analysis of some properties of these nuclei (e.g. deformation energy, neutron resonance density, neutron evaporation spectra) shows the existence of large groups of nuclei, for which the contribution of rotational modes to their level density is considerable (in spite of the traditional classification according to low-lying discrete level spectra). (author)

  10. The observation of serum CG levels in pregnant women

    The authors determined the levels of the CG contained in serum by RIA in 83 normal pregnant women and in 53 pregnant patients with ICP. The result showed that CG levels of ICP patients increased significantly as compared with that of normal middle and late pregnancy (P < 0.01). The routine examination of the serum CG levels in pregnant women is of great value of the earlier diagnosis to ICP and treatment as well as health care of perinatal period

  11. Solar Activity Studies using Microwave Imaging Observations

    Gopalswamy, N.

    2016-01-01

    We report on the status of solar cycle 24 based on polar prominence eruptions (PEs) and microwave brightness enhancement (MBE) information obtained by the Nobeyama radioheliograph. The north polar region of the Sun had near-zero field strength for more than three years (2012-2015) and ended only in September 2015 as indicated by the presence of polar PEs and the lack of MBE. The zero-polar-field condition in the south started only around 2013, but it ended by June 2014. Thus the asymmetry in the times of polarity reversal switched between cycle 23 and 24. The polar MBE is a good proxy for the polar magnetic field strength as indicated by the high degree of correlation between the two. The cross-correlation between the high- and low-latitude MBEs is significant for a lag of approximately 5.5 to 7.3 years, suggesting that the polar field of one cycle indicates the sunspot number of the next cycle in agreement with the Babcock-Leighton mechanism of solar cycles. The extended period of near-zero field in the north-polar region should result in a weak and delayed sunspot activity in the northern hemisphere in cycle 25.

  12. Nestling activity levels during begging behaviour predicts activity level and body mass in adulthood

    Luke S.C. McCowan

    2014-09-01

    Full Text Available Across a range of species including humans, personality traits, or differences in behaviour between individuals that are consistent over time, have been demonstrated. However, few studies have measured whether these consistent differences are evident in very young animals, and whether they persist over an individual’s entire lifespan. Here we investigated the begging behaviour of very young cross-fostered zebra finch nestlings and the relationship between that and adult activity levels. We found a link between the nestling activity behaviour head movements during begging, measured at just five and seven days after hatching, and adult activity levels, measured when individuals were between three and three and a half years old. Moreover, body mass was found to be negatively correlated with both nestling and adult activity levels, suggesting that individuals which carry less body fat as adults are less active both as adults and during begging as nestlings. Our work suggests that the personality traits identified here in both very young nestlings and adults may be linked to physiological factors such as metabolism or environmental sources of variation. Moreover, our work suggests it may be possible to predict an individual’s future adult personality at a very young age, opening up new avenues for future work to explore the relationship between personality and a number of aspects of individual life history and survival.

  13. Nestling activity levels during begging behaviour predicts activity level and body mass in adulthood.

    McCowan, Luke S C; Griffith, Simon C

    2014-01-01

    Across a range of species including humans, personality traits, or differences in behaviour between individuals that are consistent over time, have been demonstrated. However, few studies have measured whether these consistent differences are evident in very young animals, and whether they persist over an individual's entire lifespan. Here we investigated the begging behaviour of very young cross-fostered zebra finch nestlings and the relationship between that and adult activity levels. We found a link between the nestling activity behaviour head movements during begging, measured at just five and seven days after hatching, and adult activity levels, measured when individuals were between three and three and a half years old. Moreover, body mass was found to be negatively correlated with both nestling and adult activity levels, suggesting that individuals which carry less body fat as adults are less active both as adults and during begging as nestlings. Our work suggests that the personality traits identified here in both very young nestlings and adults may be linked to physiological factors such as metabolism or environmental sources of variation. Moreover, our work suggests it may be possible to predict an individual's future adult personality at a very young age, opening up new avenues for future work to explore the relationship between personality and a number of aspects of individual life history and survival. PMID:25279258

  14. PSA Level 2 activities for RBMK reactors

    Probabilistic safety analyses (PSAs) of the boiling water graphite moderated pressure tube reactors (RBMKs) have been developed only recently and they are limited to Level 1. Activities at the IAEA were first motivated because of the difficulties to characterize core damage for RBMK reactors. Core damage probability is used in documents of the IAEA as a convenient single valued measure, for example for probabilistic safety criteria. The limited number of PSAs that have been completed for the RBMK reactors have shown that several special features of these channel type reactors necessitate revisiting of the characterization of core damage for these reactors. Furthermore, it has become increasingly evident that detailed deterministic analysis of DBAs and beyond design basis accidents reveal considerable insights into RBMK response to various accident conditions. These analyses can also help in better characterizing the outstanding phenomenological uncertainties, improved EOPs and AM strategies, including potential risk-beneficial accident negative backfits. The deterministic efforts should be focused first on elucidating accident progression processes and phenomena, and second on finding, qualifying and implementing procedures to minimize the risk of severe accident states The IAEA PSA procedures were mainly developed in New of vessel type LWRs, and would therefore require extensions to make them directly applicable. to channel type reactors. (author) (author)

  15. Wind profiler observations of a monsoon low-level jet over a tropical Indian station

    M. C. R. Kalapureddy

    2007-11-01

    Full Text Available Three-year high-resolution wind observations of the wind profiler have been utilized to characterize the diurnal and seasonal features of the monsoon Low-Level Jet (LLJ over a tropical station, Gadanki (13.5° N, 79.2° E, with a focus on the diurnal variability of low-level winds. The Boreal summer monsoon winds show a conspicuously strong westerly LLJ with average wind speed exceeding 20 m s−1. The L-band wind profiler measurements have shown an advantage of better height and time resolutions over the conventional radiosonde method for diurnal wind measurements. An interesting diurnal oscillation of LLJ core has been observed. It is varying in the height range of 1.8±0.6 km with the maximum and minimum intensity noticed during the early morning and afternoon hours, respectively. The jet core (wind maxima height is observed to coincide with the inversion height. Strong wind shears are normally located beneath the LLJ core. The sole wind profiler observations are capable of identifying the monsoon phases, such as onset, break and active spells, etc. The mutual influence between the LLJ and the boundary layer has been discussed. One notices that the observed LLJ diurnal structures depend on the local convective activity, wind shears and turbulence activity associated with boundary layer winds. The day-to-day change in the LLJ structure depends on the latitudinal position of the LLJ core.

  16. TRMM/LIS and PR Observations and Thunderstorm Activity

    Ohita, S.; Morimoto, T.; Kawasaki, Z. I.; Ushio, T.

    2005-12-01

    Thunderstorms observed by TRMM/PR and LIS have been investigating, and Lightning Research Group of Osaka University (LRG-OU) has unveiled several interesting features. Correlation between lightning activities and the snow depth of convective clouds may follow the power-five law. The power five law means that the flash density is a function of the snow-depth to power five. The definition of snow depth is the height of detectable cloud tops by TRMM/PR from the climatological freezing level, and it may be equivalent to the length of the portion where the solid phase precipitation particles exist. This is given by examining more than one million convective clouds, and we conclude that the power five law should be universal from the aspect of the statistic. Three thunderstorm active areas are well known as "Three World Chimneys", and those are the Central Africa, Amazon of the South America, and South East Asia. Thunderstorm activities in these areas are expected to contribute to the distribution of thermal energy around the equator to middle latitude regions. Moreover thunderstorm activity in the tropical region is believed to be related with the average temperature of our planet earth. That is why long term monitoring of lightning activity is required. After launching TRMM we have accumulated seven-year LIS observations, and statistics for three world chimneys are obtained. We have recognized the additional lightning active area, and that is around the Maracaibo lake in Venezuera. We conclude that this is because of geographical features of the Maracaibo lake and the continuous easterly trade wind. Lightning Activity during El Niño period is another interesting subject. LRGOU studies thunderstorm occurrences over west Indonesia and south China, and investigates the influence of El Nino on lightning . We compare the statistics between El Nino and non El Nino periods. We learn that the lightning activity during El Niño period is higher than non El Nino period instead

  17. Observation on serum testosterone level cycles in a reared male chinese river dolphin (BAIJI)

    Objective: To study the biological significance of androgenic hormone level cycles in a reared male BAIJI dolphin. Methods: Serum testosterone levels were monthly determined with RIA in a reared BAIJI dolphin for 2 consecutive three years period(1996-98 and 2000-02). Blood samples were taken from the dorsal aspect of the tail between 10:00 to 11:00 a. m. around the 10th of each month. Results: Serum content of testosterone showed periodic changes with peaks yearly. In 1997, 1998, 1999, 2001, 2002 the peak was observed in April or May. In 2000 the peak were observed on July. Conclusion: The sexual glands of BAIJI dolphin were active from spring through autumn with a peak around April but inactive in winter. Our results suggested the BAIJI dolphin was a seasonally reproductively active animal. (authors)

  18. Nestling activity levels during begging behaviour predicts activity level and body mass in adulthood

    McCowan, Luke S.C.; Griffith, Simon C

    2014-01-01

    Across a range of species including humans, personality traits, or differences in behaviour between individuals that are consistent over time, have been demonstrated. However, few studies have measured whether these consistent differences are evident in very young animals, and whether they persist over an individual’s entire lifespan. Here we investigated the begging behaviour of very young cross-fostered zebra finch nestlings and the relationship between that and adult activity levels. We fo...

  19. SOBA: Secrecy-preserving Observable Ballot-level Audit

    Benaloh, Josh; Lazarus, Eric; Lindeman, Mark; Stark, Philip B

    2011-01-01

    SOBA is an approach to election verification that provides observers with justifiably high confidence that the reported results of an election are consistent with an audit trail ("ballots"), which can be paper or electronic. SOBA combines three ideas: (1) publishing cast vote records (CVRs) separately for each contest, so that anyone can verify that each reported contest outcome is correct, if the CVRs reflect voters' intentions with sufficient accuracy; (2) shrouding a mapping between ballots and the CVRs for those ballots to prevent the loss of privacy that could occur otherwise; (3) assessing the accuracy with which the CVRs reflect voters' intentions for a collection of contests while simultaneously assessing the integrity of the shrouded mapping between ballots and CVRs by comparing randomly selected ballots to the CVRs that purport to represent them. Step (1) is related to work by the Humboldt County Election Transparency Project, but publishing CVRs separately for individual contests rather than images...

  20. Study on the physical activity level of Turkish males

    Ramiz Arabacı

    2008-12-01

    Full Text Available The aim of this study was to investigate physical activity (PA level of the Turkish males who lived in BUrsa. A total of 365 subjects between 18 - 69 age participated to this study. To determine physical activity levels, International Physical Activity Questionnaire (IPAQ was applied. PA levels of subjects were categorized as inactive, minimum active and HEPA active by using MET method. The relations of parameters, such as their age, BMI, education, marital status, number of children, smoking and alcohol use were determined with PA level. The results were analyzed by using Chi - Square test. The participants have 1725 METmin/week average physical activity level, and 47.7 % of them were physically inactive, 30.4 % were physically minimum active and 21.9 % were physically hepa active. As a result, it can be said that the physical activity levels of Turkish males who lived in Bursa are not sufficient and the inactive people are very common.

  1. Present day sea level changes: observation and causes; Les variations actuelles du niveau de la mer: observations et causes

    Lombard, A

    2005-11-15

    Whereas sea level has changed little over the last 2000 years, it has risen at a rate of about 2 mm/year during the 20. century. This unexpected sea level rise has been attributed to the anthropogenic global warming, recorded over several decades. Sea level variations have been measured globally and precisely for about 12 years due to satellite altimeter missions Topex/Poseidon and Jason-1. These observations indicate a global mean sea level rise of about 3 mm/year since 1993, a value significantly larger than observed during previous decades. Recent observations have allowed us to quantify the various climatic factors contributing to observed sea level change: thermal expansion of sea water due to ocean warming, melting of mountain glaciers and ice sheets, and changes in the land water reservoirs. A water budget based on these new observations allows us to partly explain the observed sea level rise. In particular, we show that the thermal expansion explains only 25% of the secular sea level rise as recorded by tide-gauges over the last 50 years, while it contributes about 50% of sea level rise observed over the last decade. Meanwhile, recent studies show that glacier and ice sheet melting could contribute the equivalent of 1 mm/year in sea level rise over the last decade. In addition, the high regional variability of sea level trends revealed by satellite altimetry is mainly due to thermal expansion. There is also an important decadal spatio-temporal variability in the ocean thermal expansion over the last 50 years, which seems to be controlled by natural climate fluctuations. We question for the first time the link between the decadal fluctuations in the ocean thermal expansion and in the land reservoirs, and indeed their climatic contribution to sea level change. Finally a preliminary analysis of GRACE spatial gravimetric observations over the oceans allows us to estimate the seasonal variations in mean sea level due to ocean water mass balance variations

  2. Constraints on interseismic locking along the southern Cascadia subduction zone from historic and recent leveling and sea level observations

    Burgette, R. J.; Weldon, R. J.; Schmidt, D. A.; Williams, T. B.

    2012-12-01

    . We will also present our analysis of the existing NGS historical dataset on the southern edge of the subduction domain. Preliminary analysis of the major north-south and east-west leveling routes through northwestern California suggest that the Humboldt Bay area is experiencing tectonic subsidence at rates of up to 2 mm/yr. This is consistent with the rapid (~ 4 mm/yr) rate of relative sea level rise observed at the North Spit tide gauge. The northern California leveling data show a peak in uplift inland, in contrast to central and northern Cascadia, where the peak in uplift is near the coast or offshore. Interseismic subsidence of the coast in the Humboldt area is consistent with the locked zone extending east of the coastline, in contrast to what is observed in Oregon where the locked zone is offshore, and corresponds to an area of active onshore thrust faults. With a complete archive of the NGS data for this area, we will present refined estimates of vertical deformation rates tied to an absolute sea level reference at the North Spit tide gauge. These improved datasets will better resolve the distribution of locking along the Cascadia margin as we integrate the vertical observations with GPS-derived constraints of horizontal strain rates in an elastic model of interseismic subduction deformation.

  3. Entry-Level Activities in System Consultation

    Hylander, Ingrid

    2014-01-01

    System-level consultation or organizational development in schools is an area in great need of theoretical models and definitions. The three articles in this special issue provide a unique learning opportunity not only for consultation across borders but also for consultation within the same nation. In my commentary, I limit my remarks to a few…

  4. DEMETER observations of bursty MF emissions and their relation to ground-level auroral MF burst

    Broughton, M. C.; LaBelle, J.; Parrot, M.

    2014-12-01

    A survey of medium frequency (MF) electric field data from selected orbits of the Detection of Electro-Magnetic Emissions Transmitted from Earthquakes (DEMETER) spacecraft reveals 68 examples of a new type of bursty MF emissions occurring at high latitudes associated with auroral phenomena. These resemble auroral MF burst, a natural radio emission observed at ground level near local substorm onsets. Similar to MF burst, the bursty MF waves observed by DEMETER have broadband, impulsive frequency structure covering 1.5-3.0 MHz, amplitudes of 50-100 μV/m, an overall occurrence rate of ˜0.76% with higher occurrence during active times, and strong correlation with auroral hiss. The magnetic local time distribution of the MF waves observed by DEMETER shows peak occurrence rate near 18 MLT, somewhat earlier than the equivalent peak in the occurrence rate of ground level MF burst, though propagation effects and differences in the latitudes sampled by the two techniques may explain this discrepancy. Analysis of solar wind and SuperMAG data suggests that while the bursty MF waves observed by DEMETER are associated with enhanced auroral activity, their coincidence with substorm onset may not be as exact as that of ground level MF burst. One conjunction occurs in which MF burst is observed at Churchill, Manitoba, within 8 min of MF emissions detected by DEMETER on field lines approximately 1000 km southeast of Churchill. These observations may plausibly be associated with the same auroral event detected by ground level magnetometers at several Canadian observatories. Although it is uncertain, the balance of the evidence suggests that the bursty MF waves observed with DEMETER are the same phenomenon as the ground level MF burst. Hence, theories of MF burst generation in the ionosphere, such as beam-generated Langmuir waves excited over a range of altitudes or strong Langmuir turbulence generating a range of frequencies within a narrow altitude range, need to be revisited to

  5. InSAR observations of active volcanoes in Latin America

    Morales Rivera, A. M.; Chaussard, E.; Amelung, F.

    2012-12-01

    Over the last decade satellite-based interferometric synthetic aperture radar (InSAR) has developed into a well-known technique to gauge the status of active volcanoes. The InSAR technique can detect the ascent of magma to shallow levels of the volcanic plumbing system because new arriving magma pressurizes the system. This is likely associated with the inflation of the volcanic edifice and the surroundings. Although the potential of InSAR to detect magma migration is well known, the principal limitation was that only for few volcanoes frequent observations were acquired. The ALOS-1 satellite of the Japanese Aerospace Exploration Agency (JAXA) acquired a global L-band data set of 15-20 acquisitions during 2006-2011. Here we use ALOS InSAR and Small Baseline (SB) time-series methods for a ground deformation survey of Latin America with emphasis on the northern Andes. We present time-dependent ground deformation data for the volcanoes in Colombia, Ecuador and Peru and interpret the observations in terms of the dynamics of the volcanic systems.

  6. Multiple wavelength observations of a solar active region

    The Solar Maximum Mission Satellite, the Sacramento Peak Vacuum Tower Telescope, the Very Large Array and the Westerbork Synthesis Radio Telescope have been used to observe active region AR 2490 on two consecutive days at soft X-ray, ultraviolet, optical and radio wavelengths (2, 6, and 20 cm), with comparable angular resolution (2'' to 15'') and field of view (4' x 4'). The radio emissions at lambda = 6 cm and 20 cm show a double structure in which one component is associated with bright Hα plage, C IV and soft X-ray emission, and the other component is associated only with sunspots. No radiation at lambda = 2 cm is detected in this latter component. Coronal temperature and emission measure derived from X-ray lines indicate that the dominant radiation mechanism of the plage-associated component is due to thermal bremsstrahlung while the gyroresonance absorption coefficient must be invoked to account for the high brightness temperature (Tsub(b) approx. equal to 2 x 106 K) observed in the sunspot associated component. The high magnetic field strength needed (600 G at a level where T approx. equal to 2 x 106 K) is explained assuming a thin transition zone, in order to reach a high electron temperature close to the sunspot, where the magnetic fields are stronger. A higher temperature gradient above sunspots is also consistent with the absence of detectable C IV emission. (orig.)

  7. Sea Levels Online: Sea Level Variations of the United States Derived from National Water Level Observation Network Stations

    National Oceanic and Atmospheric Administration, Department of Commerce — Water level records are a combination of the fluctuations of the ocean and the vertical land motion at the location of the station. Monthly mean sea level (MSL)...

  8. Valuation of companies activity on sustainability level

    S. Nadolski

    2007-03-01

    Full Text Available Purpose: Paper presents a possibilities of companies valuation due to their activity in accordance with sustainable development.Design/methodology/approach: The article describes best known methods of companies assessment (stock indices, non-financial reports and other indicators connected with sustainability. Also there is a history of indices methodology which comes from ethical, religious problems and sustainable development principles.Findings: There is still more companies interested in being (as a part of sustainability indices or other rankings. Research organizations should be concentrated on different type of rankings which contain summary report of best available techniques.Research limitations/implications: Every sustainability index or non-financial reports ranking should be important part of companies management thinking. It is important idea to create these indices for every local stock exchange. Also companies should publish true and clear non-financial reports.Originality/value: The paper concerns on existing indices and tries to make new look at sustainability problems. Important conclusions are connected with non-financial reports and possible connections between indices, rankings and best available techniques.

  9. Presenting Theoretical Ideas Prior to Inquiry Activities Fosters Theory-Level Knowledge

    Wecker, Christof; Rachel, Alexander; Heran-Dörr, Eva; Waltner, Christine; Wiesner, Hartmut; Fischer, Frank

    2013-01-01

    In the course of inquiry activities similar to those of real scientists, learners are supposed to develop knowledge both on the level of observable phenomena and on the level of explanatory theories. However, some theories involve theoretical entities (e.g., "Weiss domains") that cannot be observed directly and therefore may be hard to…

  10. Dissociation between active and observational learning from positive and negative feedback in Parkinsonism

    Kobza, Stefan; Ferrea, Stefano; Schnitzler, Alfons; Pollok, Bettina; Südmeyer, Martin; Bellebaum, Christian

    2012-01-01

    Feedback to both actively performed and observed behaviour allows adaptation of future actions. Positive feedback leads to increased activity of dopamine neurons in the substantia nigra, whereas dopamine neuron activity is decreased following negative feedback. Dopamine level reduction in unmedicated Parkinson’s Disease patients has been shown to lead to a negative learning bias, i.e. enhanced learning from negative feedback. Recent findings suggest that the neural mechanisms of active and ob...

  11. Galileo SSI Observations of Volcanic Activity at Tvashtar Catena, Io

    Milazzo, M. P.; Keszthely, L. P.; Radebaugh, J.; Davies, A. G.; Turtle, E. P.; Geissler, P.; Klaasen, K. P.; McEwen, A. S.

    2005-01-01

    Introduction: We report on the analysis of the Galileo SSI's observations of the volcanic activity at Tvashtar Catena, Io as discussed by Milazzo et al. Galileo's Solid State Imager (SSI) observed Tvashtar Catena (63 deg N, 120 deg W) four times between November 1999 and October 2001, providing a unique look at the distinctive high latitude volcanism on Io. The November 1999 observation spatially resolved, for the first time, an active extraterrestrial fissure eruption. The brightness temperature of the lavas at the November 1999 fissure eruption was 1300 K. The second observation (orbit I27, February 2000) showed a large (approx. 500 sq km) region with many, small spots of hot, active lava. The third observation was taken in conjunction with a Cassini observation in December 2000 and showed a Pele-like plume deposition ring, while the Cassini images revealed a 400 km high Pele-type plume above the Catena. The final Galileo SSI observation of Tvashtar was acquired in October 2001, and all obvious (to SSI) activity had ceased, although data from Galileo's Near Infrared Mapping Spectrometer (NIMS) indicated that there was still significant thermal emission from the Tvashtar region. We have concentrated on analyzing the style of eruption during orbit I27 (February 2000). Comparison with a lava flow cooling model indicates that the behavior of the Tvashtar eruption during I27 does not match that of "simple" advancing lava flows. Instead, it may be an active lava lake or a complex set of lava flows with episodic, overlapping (in time and space) eruptions.

  12. A 5-yr change in Norwegian 9-yr-olds' objectively assessed physical activity level

    Kolle, Elin; Steene-Johannessen, Jostein; Klasson-Heggebø, Lena;

    2009-01-01

    activity assessments that met all inclusion criteria. General linear models were used to assess the changes in physical activity between 1999-2000 and 2005. RESULTS: A significant increase in mean physical activity level and physical activity during weekends was observed between the two study periods (P...... = 0.02 and <0.001, respectively), with the patterns being similar for girls and boys. Interactions were found between change in physical activity and SES. Although the mean physical activity level and moderate-to-vigorous physical activity (MVPA) among children from low-SES groups showed no change...... over time, an increase was seen among children from middle-SES groups. Moreover, in high-SES groups, an increase was observed for mean physical activity level (girls only) between study periods, whereas no change was seen for MVPA participation. CONCLUSIONS: Nine-year-old children living in Oslo...

  13. Energy requirements and physical activity level of active elderly people in rural areas of cuba

    Obesity and non-insulin dependent diabetes mellitus (NIDDM) are common in the Third Age and increasing in Cuba. Among the life-style changes associated with increased prevalence of obesity and its related disorders, diet and activity patterns are prime candidates. The transition to this life-style model may induce a decrease in the energy needs. There is an urgent need for tools which have been validated for measuring diet and physical activity in nutritional studies in the developing world, but also a more urgent need for reference values for the total energy requirements of healthy elderly people. Regular physical activity reduces the likelihood to develop diseases that characterise the metabolic cardiovascular syndrome. Previous studies done in Havana showed values of physical activity level (PAL) which are lower than the reported for elderly subjects. Elderly people living in rural areas use to have physical activity levels which differ from the observed in urban areas. With the purpose of estimating the energy requirements, a group of 40 apparently healthy people older than 60 years of age living in a rural mountain community will be submitted to a medical, epidemiological, dietary, anthropometric and insulin resistance study. Physical activity will be determined by questionnaire and by the calculation of the PAL from the basal metabolic rate (BMR) and total energy expenditure (TEE) measured with the doubly-labelled water method (DLW). Associations with the prevalence of insulin resistance and obesity will be assessed. (author)

  14. Towards a new paradigm: Activity level balanced sustainability reporting.

    Samudhram, Ananda; Siew, Eu-Gene; Sinnakkannu, Jothee; Yeow, Paul H P

    2016-11-01

    Technoeconomic paradigms based economic growth theories suggest that waves of technological innovations drove the economic growth of advanced economies. Widespread economic degradation and pollution is an unintended consequence of such growth. Tackling environmental and social issues at firm levels would help us to overcome such issues at macro-levels. Consequently, the Triple Bottom Line (TBL) reporting approach promotes firm level economic, environmental and social performances. Incorporating Zink's (2014) 3-pillar presentation model, this paper indicates that economic, social and environmental performances tend to be reported at firm level. All three pillars are not covered evenly at the activity levels. Thus, a loophole is identified whereby excellent environmental performance at activity levels could potentially leave poor social performance undisclosed. A refinement of the TBL paradigm, whereby all three pillars are covered at the activity level, is suggested, to enhance sustainability reporting. PMID:27029522

  15. Solar Activity, Different Geomagnetic Activity Levels and Acute Myocardial Infarction

    Dimitrova, Svetla; Jordanova, Malina; Stoilova, Irina; Taseva, Tatiana; Maslarov, Dimitar

    Results on revealing a possible relationship between solar activity (SA) and geomagnetic activity (GMA) and acute myocardial infarction (AMI) morbidity are presented. Studies were based on medical data covering the period from 1.12.1995 to 31.12.2004 and concerned daily distribution of patients with AMI diagnose (in total 1192 cases) from Sofia region on the day of admission at the hospital. Analysis of variance (ANOVA) was applied to check the significance of GMA intensity effect and the type of geomagnetic storms, those caused by Magnetic Clouds (MC) and by High Speed Solar Wind Streams (HSSWS), on AMI morbidity. Relevant correlation coefficients were calculated. Results revealed statistically significant positive correlation between considered GMA indices and AMI. ANOVA revealed that AMI number was signifi- cantly increased from the day before (-1st) till the day after (+1st) geomagnetic storms with different intensities. Geomagnetic storms caused by MC were related to significant increase of AMI number in comparison with the storms caused by HSSWS. There was a trend for such different effects even on -1st and +1st day.

  16. Study on the physical activity level of Turkish males

    Ramiz Arabacı

    2008-12-01

    Full Text Available The aim of this study was to investigate physical activity (PA level of the Turkish males who lived in BUrsa. A total of 365 subjects between 18 - 69 age participated to this study. To determine physical activity levels, International Physical Activity Questionnaire (IPAQ was applied. PA levels of subjects were categorized as inactive, minimum active and HEPA active by using MET method. The relations of parameters, such as their age, BMI, education, marital status, number of children, smoking and alcohol use were determined with PA level. The results were analyzed by using Chi - Square test. The participants have 1725 METmin/week average physical activity level, and 47.7 % of them were physically inactive, 30.4 % were physically minimum active and 21.9 % were physically hepa active. As a result, it can be said that the physical activity levels of Turkish males who lived in Bursa are not sufficient and the inactive people are very common.

  17. First observation of nonyrast levels in 103Zr and level systematics of N = 63 Sr, Zr, and Mo isotones

    The β decay of the very-neutron-rich nucleus 103Y has been studied at the isotope separator IGISOL, allowing for the first time the observation of nonyrast levels in its daughter 40103Zr63. The level structure is similar to that of its isotones 101Sr and 105Mo, suggesting a large ground-state deformation of β≅ 0.4. Level systematics allows for new level assignments in both 103Zr and 105Mo. copyright 1996 The American Physical Society

  18. Radio Imaging Observations of Solar Activity Cycle and Its Anomaly

    Shibasaki, K.

    2011-12-01

    The 24th solar activity cycle has started and relative sunspot numbers are increasing. However, their rate of increase is rather slow compared to previous cycles. Active region sizes are small, lifetime is short, and big (X-class) flares are rare so far. We study this anomalous situation using data from Nobeyama Radioheliograph (NoRH). Radio imaging observations have been done by NoRH since 1992. Nearly 20 years of daily radio images of the Sun at 17 GHz are used to synthesize a radio butterfly diagram. Due to stable operation of the instrument and a robust calibration method, uniform datasets are available covering the whole period of observation. The radio butterfly diagram shows bright features corresponding to active region belts and their migration toward low latitude as the solar cycle progresses. In the present solar activity cycle (24), increase of radio brightness is delayed and slow. There are also bright features around both poles (polar brightening). Their brightness show solar cycle dependence but peaks around solar minimum. Comparison between the last minimum and the previous one shows decrease of its brightness. This corresponds to weakening of polar magnetic field activity between them. In the northern pole, polar brightening is already weakened in 2011, which means it is close to solar maximum in the northern hemisphere. Southern pole does not show such feature yet. Slow rise of activity in active region belt, weakening of polar activity during the minimum, and large north-south asymmetry in polar activity imply that global solar activity and its synchronization are weakening.

  19. Ferromagnetic interaction model of activity level in workplace communication

    Akitomi, Tomoaki; Ara, Koji; Watanabe, Jun-ichiro; Yano, Kazuo

    2013-03-01

    The nature of human-human interaction, specifically, how people synchronize with each other in multiple-participant conversations, is described by a ferromagnetic interaction model of people’s activity levels. We found two microscopic human interaction characteristics from a real-environment face-to-face conversation. The first characteristic is that people quite regularly synchronize their activity level with that of the other participants in a conversation. The second characteristic is that the degree of synchronization increases as the number of participants increases. Based on these microscopic ferromagnetic characteristics, a “conversation activity level” was modeled according to the Ising model. The results of a simulation of activity level based on this model well reproduce macroscopic experimental measurements of activity level. This model will give a new insight into how people interact with each other in a conversation.

  20. Active listening in medical consultations: development of the Active Listening Observation Scale (ALOS-global).

    Fassaert, T.; van Dulmen, S.; Schellevis, F.; BENSING, J

    2007-01-01

    OBJECTIVE: Active listening is a prerequisite for a successful healthcare encounter, bearing potential therapeutic value especially in clinical situations that require no specific medical intervention. Although generally acknowledged as such, active listening has not been studied in depth. This paper describes the development of the Active Listening Observation Scale (ALOS-global), an observation instrument measuring active listening and its validation in a sample of general practice consulta...

  1. Dissociation between active and observational learning from positive and negative feedback in Parkinsonism.

    Stefan Kobza

    Full Text Available Feedback to both actively performed and observed behaviour allows adaptation of future actions. Positive feedback leads to increased activity of dopamine neurons in the substantia nigra, whereas dopamine neuron activity is decreased following negative feedback. Dopamine level reduction in unmedicated Parkinson's Disease patients has been shown to lead to a negative learning bias, i.e. enhanced learning from negative feedback. Recent findings suggest that the neural mechanisms of active and observational learning from feedback might differ, with the striatum playing a less prominent role in observational learning. Therefore, it was hypothesized that unmedicated Parkinson's Disease patients would show a negative learning bias only in active but not in observational learning. In a between-group design, 19 Parkinson's Disease patients and 40 healthy controls engaged in either an active or an observational probabilistic feedback-learning task. For both tasks, transfer phases aimed to assess the bias to learn better from positive or negative feedback. As expected, actively learning patients showed a negative learning bias, whereas controls learned better from positive feedback. In contrast, no difference between patients and controls emerged for observational learning, with both groups showing better learning from positive feedback. These findings add to neural models of reinforcement-learning by suggesting that dopamine-modulated input to the striatum plays a minor role in observational learning from feedback. Future research will have to elucidate the specific neural underpinnings of observational learning.

  2. Active Ageing Level of Older Persons: Regional Comparison in Thailand

    Haque, Md. Nuruzzaman

    2016-01-01

    Active ageing level and its discrepancy in different regions (Bangkok, Central, North, Northeast, and South) of Thailand have been examined for prioritizing the policy agenda to be implemented. Attempt has been made to test preliminary active ageing models for Thai older persons and hence active ageing index (AAI, ranges from 0 to 1) has been estimated. Using nationally representative data and confirmatory factor analysis approach, this study justified active ageing models for female and male older persons in Thailand. Results revealed that active ageing level of Thai older persons is not high (mean AAIs for female and male older persons are 0.64 and 0.61, resp., and those are significantly different (p health and economic security, to promote participation in social groups and longer working lives, and to arrange learning programs, would be helpful for increasing older persons' active ageing level in Thailand.

  3. Active Ageing Level of Older Persons: Regional Comparison in Thailand

    Md. Nuruzzaman Haque

    2016-01-01

    Active ageing level and its discrepancy in different regions (Bangkok, Central, North, Northeast, and South) of Thailand have been examined for prioritizing the policy agenda to be implemented. Attempt has been made to test preliminary active ageing models for Thai older persons and hence active ageing index (AAI, ranges from 0 to 1) has been estimated. Using nationally representative data and confirmatory factor analysis approach, this study justified active ageing models for female and male...

  4. Testing lifting capacity : Validity of determining effort level by means of observation

    Reneman, M.F; Fokkens, A.S.; Dijkstra, P.U.; Geertzen, J.H.B.; Groothoff, J.W.

    2005-01-01

    Study Design. Video observation study. Objectives. To establish the validity of determining effort level by visual observation of a lifting test. Summary of Background Data. Determining effort level during a lifting test is critical for interpretation of test performance, yet the validity of these d

  5. Observations of ice multiplication in a weakly convective cell embedded in supercooled mid-level stratus

    J. Crosier

    2011-01-01

    Full Text Available Simultaneous observations of cloud microphysical properties were obtained by in-situ aircraft measurements and ground based Radar/Lidar. Widespread mid-level stratus cloud was present below a temperature inversion (~5 °C magnitude at 3.6 km altitude. Localised convection (peak updraft 1.5 m s−1 was observed 20 km west of the Radar station. This was associated with convergence at 2.5 km altitude. The convection was unable to penetrate the inversion capping the mid-level stratus.

    The mid-level stratus cloud was vertically thin (~400 m, horizontally extensive (covering 100 s of km and persisted for more than 24 h. The cloud consisted of supercooled water droplets and small concentrations of large (~1 mm stellar/plate like ice which slowly precipitated out. This ice was nucleated at temperatures greater than −12.2 °C and less than −10.0 °C, (cloud top and cloud base temperatures, respectively. No ice seeding from above the cloud layer was observed. This ice was formed by primary nucleation, either through the entrainment of efficient ice nuclei from above/below cloud, or by the slow stochastic activation of immersion freezing ice nuclei contained within the supercooled drops. Above cloud top significant concentrations of sub-micron aerosol were observed and consisted of a mixture of sulphate and carbonaceous material, a potential source of ice nuclei. Particle number concentrations (in the size range 0.1<D<3.0 μm were measured above and below cloud in concentrations of ~25 cm−3. Ice crystal concentrations in the cloud were constant at around 0.2 L−1. It is estimated that entrainment of aerosol particles into cloud cannot replenish the loss of ice nuclei from the cloud layer via precipitation.

    Precipitation from the mid-level stratus evaporated before reaching the surface, whereas rates of up to 1 mm h−1 were observed below the convective feature. There is strong

  6. Observation of low frequency electromagnetic activity at 1000 km altitude

    N. Ivchenko

    Full Text Available We present a statistical study of low frequency fluctuations of electric and magnetic fields, commonly interpreted as Alfvénic activity. The data base consists of six months of electric and magnetic field measurements by the Astrid-2 microsatellite. The occurrence of the events is studied with respect to the location and general activity. Large regions of broadband Alfvénic activity are persistently observed in the cusp/cleft and, during the periods of high geo-magnetic activity, also in the pre-midnight sector of the auroral oval.

    Key words. Ionosphere (auroral ionosphere – Space plasma physics (waves and instabilities – Magnetospheric physics (magnetosphere-ionosphere interactions

  7. Observation of optical-fiber Kerr nonlinearity at the single-photon level

    Matsuda, Nobuyuki; Mitsumori, Yasuyoshi; Kosaka, Hideo; Edamatsu, Keiichi; 10.1038/nphoton.2008.292

    2012-01-01

    Optical fibers have been enabling numerous distinguished applications involving the operation and generation of light, such as soliton transmission, light amplification, all-optical switching and supercontinuum generation. The active function of optical fibers in the quantum regime is expected to be applicable to ultralow-power all-optical signal processing and quantum information processing. Here we demonstrate the first experimental observation of optical nonlinearity at the single-photon level in an optical fiber. Taking advantage of large nonlinearity and managed dispersion of a photonic crystal fiber, we have successfully measured very small (10^(-7) ~ 10^(-8)) conditional phase shifts induced by weak coherent pulses that contain one or less than one photon per pulse on average. In spite of its tininess, the phase shift was measurable using much (~10^6 times) stronger coherent probe pulses than the pump pulses. We discuss the feasibility of quantum information processing using optical fibers, taking into...

  8. CORONAS-F observations of active phenomena on the sun

    Oraevsky, V. N.; Sobelman, I. I.; Zitnik, I. A.; Kuznetsov, V. D.; Stepanov, A. I.; Polishuk, G. M.; Kovilin, P. N.; Negoda, A. A.; Dranovsky, V. I.; Yatskiv, Ya. S.

    Complex observations in the framework of the CORONAS-F Mission aimed at the study of active phenomena inthe solar corona are described. The main features are given for the following experiments: (1) XUV-imaging spectroscopy with high temporal and spatial resolution, (2) X-ray spectroscopy, (3) X-ray and gamma-ray photometer/spectrometer, and (4) solar cosmic rays. Some new observational data on the structure and dynamics of flares and transient events are discussed along with their analysis.

  9. A Direct Coupling Coherent Quantum Observer for a Single Qubit Finite Level Quantum System

    Petersen, Ian R.

    2014-01-01

    This paper considers the problem of constructing a direct coupling quantum observer for a single qubit finite level quantum system plant. The proposed observer is a single mode linear quantum system which is shown to be able to estimate one of the plant variables in a time averaged sense. A numerical example and simulations are included to illustrate the properties of the observer.

  10. Global estimation of burned area using MODIS active fire observations

    GIGLIO, L.; G. R. van der Werf; J. T. Randerson; Collatz, G. J.; Kasibhatla, P.

    2006-01-01

    We present a method for estimating monthly burned area globally at 1° spatial resolution using Terra MODIS data and ancillary vegetation cover information. Using regression trees constructed for 14 different global regions, MODIS active fire observations were calibrated to ''true'' burned area estimates derived from 500-m MODIS imagery based on the conventional assumption that burned area is proportional to counts of fire pixels. Unlike earlier methods, we...

  11. Cooling Active Region Loops Observed With SXT and TRACE

    Winebarger, A R; Winebarger, Amy R.; Warren, Harry P.

    2005-01-01

    An Impulsive Heating Multiple Strand (IHMS) Model is able to reproduce the observational characteristics of EUV (~ 1 MK) active region loops. This model implies that some of the loops must reach temperatures where X-ray filters are sensitive (> 2.5 MK) before they cool to EUV temperatures. Hence, some bright EUV loops must be preceded by bright X-ray loops. Previous analysis of X-ray and EUV active region observations, however, have concluded that EUV loops are not preceded by X-ray loops. In this paper, we examine two active regions observed in both X-ray and EUV filters and analyze the evolution of five loops over several hours. These loops first appear bright in the X-ray images and later appear bright in the EUV images. The delay between the appearance of the loops in the X-ray and EUV filters is as little as 1 hour and as much as 3 hours. All five loops appear as single ``monolithic'' structures in the X-ray images, but are resolved into many smaller structures in the (higher resolution) EUV images. The ...

  12. Murine erythrocytes contain high levels of lysophospholipase activity

    Kamp, J.A.F. op den; Roelofsen, B.; Sanderink, G.; Middelkoop, E.; Hamer, R.

    1984-01-01

    Murine erythrocytes were found to be unique in the high levels of lysophospholipase activity in the cytosol of these cells. The specific activity of the enzyme in the cytosol of the murine cells is 10-times higher than in the cytosol of rabbit erythrocytes and approximately three orders of magnitude

  13. Active Ageing Level of Older Persons: Regional Comparison in Thailand

    Md. Nuruzzaman Haque

    2016-01-01

    Full Text Available Active ageing level and its discrepancy in different regions (Bangkok, Central, North, Northeast, and South of Thailand have been examined for prioritizing the policy agenda to be implemented. Attempt has been made to test preliminary active ageing models for Thai older persons and hence active ageing index (AAI, ranges from 0 to 1 has been estimated. Using nationally representative data and confirmatory factor analysis approach, this study justified active ageing models for female and male older persons in Thailand. Results revealed that active ageing level of Thai older persons is not high (mean AAIs for female and male older persons are 0.64 and 0.61, resp., and those are significantly different (p<0.001. Mean AAI in Central region is lower than North, Northeast, and South regions but there is no significant difference in the latter three regions of Thailand. Special emphasis should be given to Central region and policy should be undertaken for increasing active ageing level. Implementation of an Integrated Active Ageing Package (IAAP, containing policies for older persons to improve their health and economic security, to promote participation in social groups and longer working lives, and to arrange learning programs, would be helpful for increasing older persons’ active ageing level in Thailand.

  14. Continuous gravity observations at active volcanoes through superconducting gravimeters

    Carbone, Daniele; Greco, Filippo

    2016-04-01

    Continuous gravity measurements at active volcanoes are usually taken through spring gravimeters that are easily portable and do not require much power to work. However, intrinsic limitations dictate that, when used in continuous, these instruments do not provide high-quality data over periods longer than some days. Superconducting gravimeters (SG), that feature a superconducting sphere in a magnetic field as the proof mass, provide better-quality data than spring gravimeters, but are bigger and need mains electricity to work, implying that they cannot be installed close to the active structures of high volcanoes. An iGrav SG was installed on Mt. Etna (Italy) in September 2014 and has worked almost continuously since then. It was installed about 6km from the active craters in the summit zone of the volcano. Such distance is normally too much to observe gravity changes due to relatively fast (minutes to days) volcanic processes. Indeed, mass redistributions in the shallowest part of the plumbing system induce short-wavelength gravity anomalies, centered below the summit craters. Nevertheless, thanks to the high precision and long-term stability of SGs, it was possible to observe low-amplitude changes over a wide range of timescales (minutes to months), likely driven by volcanic activity. Plans are in place for the implementation of a mini-array of SGs at Etna.

  15. Active Crohn's disease is associated with low vitamin D levels

    Jørgensen, Søren Peter; Hvas, Christian Lodberg; Agnholt, Jørgen;

    2013-01-01

    BACKGROUND AND AIMS: Crohn's disease prevalence increases with increasing latitude. Because most vitamin D comes from sunlight exposure and murine models of intestinal inflammation have demonstrated beneficial effects of 1,25-(OH)(2) vitamin D treatment, we hypothesised that Crohn's disease...... activity is associated with low vitamin D levels. METHODS: In a cross-sectional study of 182 CD patients and 62 healthy controls, we measured serum 25-OH vitamin D. Stratified analysis was used to compare 25-OH vitamin D levels with Crohn's disease activity index, C-reactive protein, smoking status, intake...... of oral vitamin D supplements and seasonal variation in CD patients and healthy controls. RESULTS: Serum 25-OH vitamin D was inversely associated with disease activity: Median 25-OH vitamin D levels of Crohn's disease in remission, mildly, and moderately active diseases evaluated by Crohn's disease...

  16. Algorithmic recognition of anomalous time intervals in sea-level observations

    Getmanov, V. G.; Gvishiani, A. D.; Kamaev, D. A.; Kornilov, A. S.

    2016-03-01

    The problem of the algorithmic recognition of anomalous time intervals in the time series of the sea-level observations conducted by the Russian Tsunami Warning Survey (RTWS) is considered. The normal and anomalous sea-level observations are described. The polyharmonic models describing the sea-level fluctuations on the short time intervals are constructed, and sea-level forecasting based on these models is suggested. The algorithm for the recognition of anomalous time intervals is developed and its work is tested on the real RTWS data.

  17. Geodetic observation of sea-level change and crustal deformation in the Baltic Sea region

    Richter, A.; Groh, A.; Dietrich, R.

    Based on tide gauge observations spanning almost 200 years, homogeneous time series of the mean relative sea level were derived for nine sites at the southern coast of the Baltic Sea. Our regionally concentrated data were complemented by long-term relative sea-level records retrieved from the data base of the Permanent Service for Mean Sea Level (PSMSL). From these records relative sea-level change rates were derived at 51 tide gauge stations for the period between 1908 and 2007. A minimum observation time of 60 years is required for the determination of reliable sea-level rates. At present, no anthropogenic acceleration in sea-level rise is detected in the tide gauge observations in the southern Baltic. The spatial variation of the relative sea-level rates reflects the fingerprint of GIA-induced crustal uplift. Time series of extreme sea levels were also inferred from the tide gauge records. They were complemented by water level information from historic storm surge marks preserved along the German Baltic coast. Based on this combined dataset the incidence and spatial variation of extreme sea levels induced by storm surges were analysed yielding important information for hazard assessments. Permanent GPS observations were used to determine recent crustal deformation rates for 44 stations in the Baltic Sea region. The GPS derived height change rates were applied to reduce the relative sea-level changes observed by tide gauges yielding an estimate for the eustatic sea-level change. For 13 tide gauge-GPS colocation sites a mean eustatic sea-level trend of 1.3 mm/a was derived for the last 100 years.

  18. Both novelty and expertise increase action observation network activity

    Sook-Lei eLiew

    2013-09-01

    Full Text Available Our experiences with others affect how we perceive their actions. In particular, activity in bilateral premotor and parietal cortices during action observation, collectively known as the action observation network (AON, is modulated by one’s expertise with the observed actions or individuals. However, conflicting reports suggest that AON activity is greatest both for familiar and unfamiliar actions. The current study examines the effects of different types and amounts of experience (e.g., visual, interpersonal, personal on AON activation. fMRI was used to scan 16 healthy participants without prior experience with individuals with amputations (novices, 11 experienced occupational therapists (OTs who had varying amounts of experience with individuals with amputations, and one individual born with below-elbow residual limbs (participant CJ, as they viewed video clips of goal-matched actions performed by an individual with residual limbs and by an individual with hands. Participants were given increased visual exposure to actions performed by both effectors midway through the scanning procedure. Novices demonstrated a large AON response to the initial viewing of an individual with residual limbs compared to one with hands, but this signal was attenuated after they received visual exposure to both effectors. In contrast, OTs, who had moderate familiarity with residual limbs, demonstrated a lower AON response upon initial viewing—similar to novices after they received visual exposure. At the other extreme, CJ, who has extreme familiarity with residual limbs both visually and motorically, shows a largely increased left-lateralized AON response, exceeding that of novices and experienced OTs, when viewing the residual limb compared to hand actions. These results suggest that a nuanced model of AON engagement is needed to explain how cases of both extreme experience (CJ and extreme novelty (novices can result in the greatest AON activity.

  19. Relationship between level of neutral buoyancy and dual-Doppler observed mass detrainment levels in deep convection

    G. L. Mullendore

    2013-01-01

    Full Text Available Although it is generally accepted that the level of neutral buoyancy (LNB is only a coarse estimate of updraft depth, the LNB is still used to understand and predict storm structure in both observations and modeling. This study uses case studies to quantify the variability associated with using environmental soundings to predict detrainment levels. Nine dual-Doppler convective cases were used to determine the observed level of maximum detrainment (LMD to compare with the LNB. The LNB for each case was calculated with a variety of methods and with a variety of sources (including both observed and simulated soundings. The most representative LNB was chosen as the proximity sounding from NARR using the most unstable parcel and including ice processes.

    The observed cases were a mix of storm morphologies, including both supercell and multicell storms. As expected, the LMD was generally below the LNB, the mean offset for all cases being 2.2 km. However, there was a marked difference between the supercell and non-supercell cases. The two supercell cases had LMDs of 0.3 km and 0.0 km below the LNB. The remaining cases had LMDs that ranged from 4.0 km below to 1.6 km below the LNB, with a mean offset of 2.8 km below. Observations also showed that evolution of the LMD over the lifetime of the storm can be significant (e.g., >2 km altitude change in 30 min, and this time evolution is lacking from models with coarse time steps, missing significant changes in detrainment levels that may strongly impact the amount of boundary layer mass transported to the upper troposphere and lower stratosphere.

  20. Great Lakes Daily Ice Observations at NOAA Water Level Gauge Sites

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains daily visual ice observations taken yearly from 1 November to 30 April at NOAA/National Ocean Service water level gauge sites in the Great...

  1. Spectroscopic Observations of Fe XVIII in Solar Active Regions

    Teriaca, Luca; Curdt, Werner

    2012-01-01

    The large uncertainties associated with measuring the amount of high temperature emission in solar active regions represents a significant impediment to making progress on the coronal heating problem. Most current observations at temperatures of 3 MK and above are taken with broad band soft X-ray instruments. Such measurements have proven difficult to interpret unambiguously. Here we present the first spectroscopic observations of the Fe XVIII 974.86 AA emission line in an on-disk active region taken with then SUMER instrument on SOHO. Fe XVIII has a peak formation temperature of 7.1 MK and provides important constraints on the amount of impulsive heating in the corona. Detailed evaluation of the spectra and comparison of the SUMER data with soft X-ray images from the XRT on Hinode confirm that this line is unblended. We also compare the spectroscopic data with observations from the AIA 94 AA channel on SDO. The AIA 94 AA channel also contains Fe XVIII, but is blended with emission formed at lower temperature...

  2. SPECTROSCOPIC OBSERVATIONS OF Fe XVIII IN SOLAR ACTIVE REGIONS

    Teriaca, Luca; Curdt, Werner [Max-Planck-Institut fuer Sonnensystemforschung, Max-Planck-Str. 2, 37191 Katlenburg-Lindau (Germany); Warren, Harry P. [Space Science Division, Naval Research Laboratory, Washington, DC 20375 (United States)

    2012-08-01

    The large uncertainties associated with measuring the amount of high temperature emission in solar active regions (ARs) represents a significant impediment to making progress on the coronal heating problem. Most current observations at temperatures of 3 MK and above are taken with broadband soft X-ray instruments. Such measurements have proven difficult to interpret unambiguously. Here, we present the first spectroscopic observations of the Fe XVIII 974.86 A emission line in an on-disk AR taken with the SUMER instrument on SOHO. Fe XVIII has a peak formation temperature of 7.1 MK and provides important constraints on the amount of impulsive heating in the corona. Detailed evaluation of the spectra and comparison of the SUMER data with soft X-ray images from the X-Ray Telescope on Hinode confirm that this line is unblended. We also compare the spectroscopic data with observations from the Atmospheric Imaging Assembly (AIA) 94 A channel on the Solar Dynamics Observatory. The AIA 94 A channel also contains Fe XVIII, but is blended with emission formed at lower temperatures. We find that it is possible to remove the contaminating blends and form relatively pure Fe XVIII images that are consistent with the spectroscopic observations from SUMER. The observed spectra also contain the Ca XIV 943.63 A line that, although a factor 2-6 weaker than the Fe XVIII 974.86 A line, allows us to probe the plasma around 3.5 MK. The observed ratio between the two lines indicates (isothermal approximation) that most of the plasma in the brighter Fe XVIII AR loops is at temperatures between 3.5 and 4 MK.

  3. Spectroscopic Observations of Fe XVIII in Solar Active Regions

    Teriaca, Luca; Warren, Harry P.; Curdt, Werner

    2012-08-01

    The large uncertainties associated with measuring the amount of high temperature emission in solar active regions (ARs) represents a significant impediment to making progress on the coronal heating problem. Most current observations at temperatures of 3 MK and above are taken with broadband soft X-ray instruments. Such measurements have proven difficult to interpret unambiguously. Here, we present the first spectroscopic observations of the Fe XVIII 974.86 Å emission line in an on-disk AR taken with the SUMER instrument on SOHO. Fe XVIII has a peak formation temperature of 7.1 MK and provides important constraints on the amount of impulsive heating in the corona. Detailed evaluation of the spectra and comparison of the SUMER data with soft X-ray images from the X-Ray Telescope on Hinode confirm that this line is unblended. We also compare the spectroscopic data with observations from the Atmospheric Imaging Assembly (AIA) 94 Å channel on the Solar Dynamics Observatory. The AIA 94 Å channel also contains Fe XVIII, but is blended with emission formed at lower temperatures. We find that it is possible to remove the contaminating blends and form relatively pure Fe XVIII images that are consistent with the spectroscopic observations from SUMER. The observed spectra also contain the Ca XIV 943.63 Å line that, although a factor 2-6 weaker than the Fe XVIII 974.86 Å line, allows us to probe the plasma around 3.5 MK. The observed ratio between the two lines indicates (isothermal approximation) that most of the plasma in the brighter Fe XVIII AR loops is at temperatures between 3.5 and 4 MK.

  4. Active region upflows. I. Multi-instrument observations

    Vanninathan, K.; Madjarska, M. S.; Galsgaard, K.; Huang, Z.; Doyle, J. G.

    2015-12-01

    Context. We study upflows at the edges of active regions, called AR outflows, using multi-instrument observations. Aims: This study intends to provide the first direct observational evidence of whether chromospheric jets play an important role in furnishing mass that could sustain coronal upflows. The evolution of the photospheric magnetic field, associated with the footpoints of the upflow region and the plasma properties of active region upflows is investigated with the aim of providing information for benchmarking data-driven modelling of this solar feature. Methods: We spatially and temporally combine multi-instrument observations obtained with the Extreme-ultraviolet Imaging Spectrometer on board the Hinode, the Atmospheric Imaging Assembly and the Helioseismic Magnetic Imager instruments on board the Solar Dynamics Observatory and the Interferometric BI-dimensional Spectro-polarimeter installed at the National Solar Observatory, Sac Peak, to study the plasma parameters of the upflows and the impact of the chromosphere on active region upflows. Results: Our analysis shows that the studied active region upflow presents similarly to those studied previously, i.e. it displays blueshifted emission of 5-20 kms-1 in Fe xii and Fe xiii and its average electron density is 1.8 × 109 cm-3 at 1 MK. The time variation of the density is obtained showing no significant change (in a 3σ error). The plasma density along a single loop is calculated revealing a drop of 50% over a distance of ~20 000 km along the loop. We find a second velocity component in the blue wing of the Fe xii and Fe xiii lines at 105 kms-1 reported only once before. For the first time we study the time evolution of this component at high cadence and find that it is persistent during the whole observing period of 3.5 h with variations of only ±15 kms-1. We also, for the first time, study the evolution of the photospheric magnetic field at high cadence and find that magnetic flux diffusion is

  5. Observation of Andreev bound states at spin-active interfaces

    Beckmann, Detlef; Wolf, Michael Johannes [KIT, Institut fuer Nanotechnologie (Germany); Huebler, Florian [KIT, Institut fuer Nanotechnologie (Germany); KIT, Institut fuer Festkoerperphysik (Germany); Loehneysen, Hilbert von [KIT, Institut fuer Festkoerperphysik (Germany); KIT, Physikalisches Institut (Germany)

    2013-07-01

    We report on high-resolution differential conductance experiments on nanoscale superconductor/ferromagnet tunnel junctions with ultra-thin oxide tunnel barriers. We observe subgap conductance features which are symmetric with respect to bias, and shift according to the Zeeman energy with an applied magnetic field. These features can be explained by resonant transport via Andreev bound states induced by spin-active scattering at the interface. From the energy and the Zeeman shift of the bound states, both the magnitude and sign of the spin-dependent interfacial phase shifts between spin-up and spin-down electrons can be determined. These results contribute to the microscopic insight into the triplet proximity effect at spin-active interfaces.

  6. Magnetospheric impulse response for many levels of geomagnetic activity

    The temporal relationship between the solar wind and magnetospheric activity has been studied using 34 intervals of high time resolution IMP 8 solar wind data and the corresponding AL auroral activity index. The median value of the AL index for each interval were utilized to rank the intervals according to geomagnetic activity level. The linear prediction filtering technique was then applied to model magnetospheric response as measured by the AL index to the solar wind input function VB/sub s/. The linear prediction filtering routine produces a filter of time-lagged response coefficients which estimates the most general linear relationship between the chosen input and output parameters of the magnetospheric system. It is found that the filters are composed of two response pulses speaking at time lags of 20 and 60 min. The amplitude of the 60-min pulse is the larger for moderate activity levels, while the 20-min pulse is the larger for strong activity levels. A possible interpretation is that the 20-min pulse represents magnetospheric activity driven directly by solar wind coupling and that the 60-min pulse represents magnetospheric activity driven by the relase of energy previously stored in the magnetotal. If this interpretation is correct, the linear filtering results suggest that both the driven and the unloading models of magnetospheric response are important facets of a more comprehensive response model

  7. ACTIVE OBSERVATION TACTICS IN PATIENTS WITH KIDNEY NEOPLASMS

    B. Ya. Alekseev

    2012-01-01

    Full Text Available As of now, about 40-60% of the first detected kidney tumors are accidentally diagnosed. These are most often asymptomatic small kidney tumors (SKT without distant metastases; 15–20% of them are benign. A number of studies have revealed that kidney malignant tumors grow slowly and spread extremely rarely, as evidenced by a histological study. These and other data formed the basis for the active observation tactic that became possible and acceptable in well-selected patients, in elderly patients with SKT and severe comorbidity in particular.

  8. Active region upflows: 1. Multi-instrument observations

    Vanninathan, K.; Madjarska, M. S.; Galsgaard, K.; Huang, Z; Doyle, J. G.

    2015-01-01

    Upflows at the edges of active regions (ARs) are studied by spatially and temporally combining multi-instrument observations obtained with EIS/Hinode, AIA and HMI/SDO and IBIS/NSO, to derive their plasma parameters. This information is used for benchmarking data-driven modelling of the upflows (Galsgaard et al., 2015). The studied AR upflow displays blueshifted emission of 5-20 km/s in Fe XII and Fe XIII and its average electron density is 1.8x10^9 cm^3 at 1 MK. The time variation of the dens...

  9. Effect of fluorozis on the erythrocyte antioxidant enzyme activity levels

    While the flourine level of (drinking) water was higher than normal ranges in the center of Isparta region before 1995 year, this problematic situation is solved in later years. (However) the individuals who are staying in Yenice district are still expose to high levels of fluorine because of the usage of Andik spring water (3.8 mg/L flour level) as drinking water. In this study we aimed to investigate the harmful effect of floride on human erythrocytes via antioxidant defence system and lipid peroxidation. Therefore, we studied the activities of erythrocyte antioxidant enzymes such as Superoxide Dismutase (SOD), Glutathione Peroxidase (GSH-Px) and Catalase (CAT), and the level of erythrocyte Glutathione (GSH), thiobarbituric acid reactive substance (TBARS) and the level of urine floride in high floride exposed people (children, adult and elderly). The activities of SOD, GSH-Px and CAT and the level of GSH, TBARS and urine floride were higher in 3.8 mg/L floride exposed children (Group II) than 0.8 mg/L floride exposed control children (Group I) (p0.05). The activities of SOD, GSH-Px and CAT were lower and the levels of TBARS and urine floride were higher in 3.8 mg/L floride exposed elderly people (Group VI) than 0.8 mg/L floride exposed control elderly people (Group V) (p0.05). As a result we thought that increased SOD, GSH-Px and CAT activities in floride exposed children and adult people, decreased activities of these enzymes in floride exposed elderly people, and increased TBARS in all groups may indicate floride caused oxidative damage in erythrocytes. (author)

  10. Levels of erythrocyte superoxide dismutase activity in Japanese people

    Ueda,Kazuko

    1978-12-01

    Full Text Available Levels of erythrocyte superoxide dismutase (SOD activitiy in a sample of Japanese people were determined. Blood samples were taken from new-born infants, preschool children, young and old people who had no apparent diseases and also from three anemic patients. Erythrocyte SOD activities in different age groups had a nearly normal distribution. Females had slightly lower activities than males, although the difference was statistically insignificant. The distributions of SOD activities were 12.6 +/- 2.7 (m +/- SD unit/mg Hb in young people and 11.4 +/- 3.0 in old people, indicating that erythrocyte SOD activity falls with aging. Because of low concentration of hemoglobin, SOD activities of old people expressed as unit/ml blood were much lower than in young people. Three anemic patients had slightly lower SOD activity.

  11. Classroom Management to Support Active Middle Level Classrooms

    Bryan Lloyd McCoy

    2012-01-01

    This article presents a discussion of connections between middle level concepts of teaching and learning and managing a classroom through creating opportunities for active and engaged learning. The article argues and concludes that classroom management is more about managing learning than managing behavior and that one effective way to manage student behavior is to create an environment where students continuously engage in active learning (Haydon, Borders, Embury, & Clarke, ...

  12. Classroom Management to Support Active Middle Level Classrooms

    Bryan Lloyd McCoy

    2012-09-01

    Full Text Available

    This article presents a discussion of connections between middle level concepts of teaching and learning and managing a classroom through creating opportunities for active and engaged learning. The article argues and concludes that classroom management is more about managing learning than managing behavior and that one effective way to manage student behavior is to create an environment where students continuously engage in active learning (Haydon, Borders, Embury, & Clarke, 2009.

  13. Classroom Management to Support Active Middle Level Classrooms

    Bryan Lloyd McCoy

    2012-09-01

    Full Text Available This article presents a discussion of connections between middle level concepts of teaching and learning and managing a classroom through creating opportunities for active and engaged learning. The article argues and concludes that classroom management is more about managing learning than managing behavior and that one effective way to manage student behavior is to create an environment where students continuously engage in active learning (Haydon, Borders, Embury, & Clarke, 2009.

  14. Alternative complement pathway and factor B activities in rats with altered blood levels of thyroid hormone

    Bitencourt, C.S. [Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP (Brazil); Duarte, C.G.; Azzolini, A.E.C.S.; Assis-Pandochi, A.I. [Departamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP (Brazil)

    2012-03-02

    Evaluating the activity of the complement system under conditions of altered thyroid hormone levels might help elucidate the role of complement in triggering autoimmune processes. Here, we investigated alternative pathway (AP) activity in male Wistar rats (180 ± 10 g) after altering their thyroid hormone levels by treatment with triiodothyronine (T3), propylthiouracil (PTU) or thyroidectomy. T3 and thyroxine (T4) levels were determined by chemiluminescence assays. Hemolytic assays were performed to evaluate the lytic activity of the AP. Factor B activity was evaluated using factor B-deficient serum. An anti-human factor B antibody was used to measure factor B levels in serum by radial immunodiffusion. T3 measurements in thyroidectomized animals or animals treated with PTU demonstrated a significant reduction in hormone levels compared to control. The results showed a reduction in AP lytic activity in rats treated with increasing amounts of T3 (1, 10, or 50 µg). Factor B activity was also decreased in the sera of hyperthyroid rats treated with 1 to 50 µg T3. Additionally, treating rats with 25 µg T3 significantly increased factor B levels in their sera (P < 0.01). In contrast, increased factor B concentration and activity (32%) were observed in hypothyroid rats. We conclude that alterations in thyroid hormone levels affect the activity of the AP and factor B, which may in turn affect the roles of AP and factor B in antibody production.

  15. FERMI OBSERVATIONS OF TeV-SELECTED ACTIVE GALACTIC NUCLEI

    We report on observations of TeV-selected active galactic nuclei (AGNs) made during the first 5.5 months of observations with the Large Area Telescope (LAT) on-board the Fermi Gamma-ray Space Telescope (Fermi). In total, 96 AGNs were selected for study, each being either (1) a source detected at TeV energies (28 sources) or (2) an object that has been studied with TeV instruments and for which an upper limit has been reported (68 objects). The Fermi observations show clear detections of 38 of these TeV-selected objects, of which 21 are joint GeV-TeV sources, and 29 were not in the third EGRET catalog. For each of the 38 Fermi-detected sources, spectra and light curves are presented. Most can be described with a power law of spectral index harder than 2.0, with a spectral break generally required to accommodate the TeV measurements. Based on an extrapolation of the Fermi spectrum, we identify sources, not previously detected at TeV energies, which are promising targets for TeV instruments. Evidence for systematic evolution of the γ-ray spectrum with redshift is presented and discussed in the context of interaction with the extragalactic background light.

  16. Observation of high spin levels in 131Cs from 131Ba decay

    M Sainath; Dwaraka Rani Rao; K Venkataramaniah; P C Sood

    2003-12-01

    The - and conversion electron spectra following 131Ba -decay are investigated, using HPGe detector and mini-orange electron spectrometer. Attention is particularly focussed on identifying weak transitions associated with low energy high spin levels in 131Cs level scheme earlier inferred in reaction studies but not yet observed in 131Ba decay. Our experiment identifies 15 new gammas and 6 new conversion lines in this decay. Internal conversion coefficients and multipolarities of several transitions are determined. Five new levels (3 with =7/2+ and one each with =9/2+ and 11/2-) are introduced in the 131Cs level scheme based on our observations taken together with the results from reaction studies. Spin-parity assignments to a few other levels are also suggested.

  17. Tides and lake-level variations in the great Patagonian lakes: Observations, modelling and geophysical implications.

    Marderwald, Eric; Richter, Andreas; Horwath, Martin; Hormaechea, Jose Luis; Groh, Andreas

    2016-04-01

    time series from Lagos Argentino and Viedma yields the amplitudes and phases of the lake tides for the four major tidal constituents M2, S2, O1 and K1. The maximum amplitude, corresponding to the semi-diurnal moon tide M2 in Lago Argentino, amounts to 3 mm. For the four lakes under investigation the theoretical amplitudes and phases of seven constituents (Q1, O1, P1, K1, N2, M2 and S2) are modelled accounting for the contributions of both the solid earth's body tides and the ocean tidal loading (Marderwald 2014). Both contributions involve a deformation of the earth surface and of the equipotential surfaces of the gravity field. For the load tide computation the global ocean tide model EOT11a (Savcenko and Bosch, 2012) and the Gutenberg-Bullen A earth model (Farrell, 1972) was applied and the conservation of water volume is taken into account. The comparison of the tidal signal extracted from the lake-level observations in Lagos Argentino and Viedma with the lake tide models indicates a phase shift which is most likely explained by an 1 hour phase lag of the employed global ocean tide model in the region of the highly fragmented Pacific coast. REFERENCES: Farrell, W. E., (1972). Deformation of the Earth by Surface Loads. Rev. Geophy. Space Phy., 10(3):761-797. Ivins, E., James, T., 2004. Bedrock response to Llanquihue Holocene and present-day glaciation in southernmost South America. Geophys. Res. Lett. 31 (L24613). Doi:10.1029/2004GL021500. Klemann, V., E. R. Ivins, Z. Martinec, and D. Wolf (2007), Models of active glacial isostasy roofing warm subduction: Case of the South Patagonian Ice Field, J. Geophys. Res., 112, B09405, doi: 10.1029/2006JB004818. Lange, H., Casassa, G., Ivins, E. R., Schröder, L., Fritsche, M., Richter, A., Groh, A., Dietrich, R., (2014). Observed crustal uplift near the Southern Patagonian Icefield constrains improved viscoelastic Earth models. Geophysical Research Letters, DOI: 10.1002/2013GL058419. Marderwald ER, 2014. Modelado de las mareas

  18. Default activity patterns at the neocortical microcircuit level

    Artur Luczak

    2012-06-01

    Full Text Available Even in absence of sensory stimuli cortical networks exhibit complex, self-organized activity patterns. While the function of those spontaneous patterns of activation remains poorly understood, recent studies both in vivo and in vitro have demonstrated that neocortical neurons activate in a surprisingly similar sequential order both spontaneously and following input into cortex. For example, neurons that tend to fire earlier within spontaneous bursts of activity also fire earlier than other neurons in response to sensory stimuli. These 'default patterns' can last hundreds of milliseconds and are strongly conserved under a variety of conditions. In this paper we will review recent evidence for these default patterns at the local cortical level. We speculate that cortical architecture imposes common constraints on spontaneous and evoked activity flow, which result in the similarity of the patterns.

  19. 34 CFR 300.814 - Other State-level activities.

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Other State-level activities. 300.814 Section 300.814 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION...

  20. The Arctic Observing Viewer: A Web-mapping Application for U.S. Arctic Observing Activities

    Cody, R. P.; Manley, W. F.; Gaylord, A. G.; Kassin, A.; Villarreal, S.; Barba, M.; Dover, M.; Escarzaga, S. M.; Habermann, T.; Kozimor, J.; Score, R.; Tweedie, C. E.

    2015-12-01

    interoperable resources in this way will help to ensure improved capacities for conducting activities such as assessing the status of arctic observing efforts, optimizing logistic operations, and for quickly accessing external and project-focused web resources for more detailed information and access to scientific data and derived products.

  1. Neural substrates underlying the passive observation and active control of translational egomotion.

    Huang, Ruey-Song; Chen, Ching-Fu; Sereno, Martin I

    2015-03-11

    Moving or static obstacles often get in the way while walking in daily life. Avoiding obstacles involves both perceptual processing of motion information and controlling appropriate defensive movements. Several higher-level motion areas, including the ventral intraparietal area (VIP), medial superior temporal area, parieto-insular vestibular cortex (PIVC), areas V6 and V6A, and cingulate sulcus visual area, have been identified in humans by passive viewing of optic flow patterns that simulate egomotion and object motion. However, the roles of these areas in the active control of egomotion in the real world remain unclear. Here, we used functional magnetic resonance imaging (fMRI) to map the neural substrates underlying the passive observation and active control of translational egomotion in humans. A wide-field virtual reality environment simulated a daily scenario where doors randomly swing outward while walking in a hallway. The stimuli of door-dodging events were essentially the same in two event-related fMRI experiments, which compared passive and active dodges in response to swinging doors. Passive dodges were controlled by a computer program, while active dodges were controlled by the subject. Passive dodges activated several higher-level areas distributed across three dorsal motion streams in the temporal, parietal, and cingulate cortex. Active dodges most strongly activated the temporal-vestibular stream, with peak activation located in the right PIVC. Other higher-level motion areas including VIP showed weaker to no activation in active dodges. These results suggest that PIVC plays an active role in sensing and guiding translational egomotion that moves an observer aside from impending obstacles. PMID:25762672

  2. Tropical Pacific spatial trend patterns in observed sea level: internal variability and/or anthropogenic signature?

    B. Meyssignac

    2012-01-01

    Full Text Available We investigate the spatio-temporal variability of sea level trend patterns observed by satellite altimetry since 1993, focusing on the Tropical Pacific. The objective of this study is two fold. On the basis of a 2-D past sea level reconstruction (over 1950–2009 – based on a combination of observations and ocean modelling – and multi-century control runs (i.e. with constant, preindustrial external forcing from eight coupled climate models, we investigate how these sea level trend patterns evolved during the last decades and centuries, and what their characteristic time scales are. Using 20th century coupled climate model runs, we also examine whether observed trend patterns are driven by external forcing factors (i.e. solar plus volcanic variability and changes in anthropogenic forcing or if they essentially result from natural climate variability. For this analysis, we computed sea level trend patterns over successive 17 yr windows (i.e. the length of the altimetry record both for the reconstructed sea level and model runs. We compared them to altimetry-based observed trends. The 2-D sea level reconstruction shows similar spatial trend patterns to those observed during the altimetry era. The patterns appear to have fluctuated with time with a characteristic time scale of the order of 25–30 yr. Similar behaviour is found in multi-centennial control runs of the coupled climate models. The same analysis, performed on 20th century model runs does not display significant differences. This suggests that Tropical Pacific sea level trend fluctuations are still dominated by the internal natural variability of the ocean-atmosphere coupled system. While our analysis cannot rule out any influence of anthropogenic forcing, it concludes that the latter effects on the regional sea level patterns are still hardly detectable.

  3. Can nursing students' confidence levels increase with repeated simulation activities?

    Cummings, Cynthia L; Connelly, Linda K

    2016-01-01

    In 2014, nursing faculty conducted a study with undergraduate nursing students on their satisfaction, confidence, and educational practice levels, as it related to simulation activities throughout the curriculum. The study was a voluntary survey conducted on junior and senior year nursing students. It consisted of 30 items based on the Student Satisfaction and Self-Confidence in Learning and the Educational Practices Questionnaire (Jeffries, 2012). Mean averages were obtained for each of the 30 items from both groups and were compared using T scores for unpaired means. The results showed that 8 of the items had a 95% confidence level and when combined the items were significant for p confidence and active learning. Based on these findings, it can be assumed that repeated simulation experiences can lead to an increase in student confidence and active learning. PMID:26599594

  4. Observer agreement on pen level prevalence of clinical signs in finishing pigs.

    Petersen, Henrik Hagbard; Enøe, Claes; Nielsen, Elisabeth Okholm

    2004-07-16

    Four observers performed a standard clinical examination of finisher pigs in two commercial finisher herds. In herd 1,600 finisher pigs in 44 pens were examined. The observers assessed clinical signs of lameness, umbilical hernia and tail bite according to a standardized procedure. The prevalence of the clinical signs was estimated at the pen level. The procedure was repeated after 3 months in another herd, where 730 finisher pigs in 69 pens were examined. The agreement between observer pairs was assessed using prevalence-adjusted bias-adjusted kappa (PABAK) and proportionate-agreement estimates (Ppo) and Pneg). Observer bias was present despite training and standardization of the participating observers. The highest pen level agreement for the observer pairs was found for pens that had one or more pigs with tail bite (PABAK = 0.82-1.00) and umbilical hernia (PABAK = 0.77-1.00). The agreement was fair-to-moderate for identification of pens holding one or more lame pigs (PABAK = 0.27-0.7). In general, the average agreement of observer pairs on absence of clinical signs (Pneg) was higher than for presence (Ppos). The observer bias varied between observer pairs and with the clinical signs. PMID:15325769

  5. Observing Sea Level Change and its Causes with Satellite Remote Sensing

    Boening, Carmen; Fu, Lee-Lueng; Landerer, Felix; Willis, Josh

    2016-07-01

    Sea level rise as a response to a changing climate is an imminent threat for coastal communities in the near future. Coastal zone management relies on most accurate predictions of sea level change over the coming decades for planning potential mitigation efforts. Hence, it is of high importance to accurately measure changes and understand physical processes behind them in great detail on a variety of time scales. Satellite observations of sea level height from altimetry have provided an unprecedented understanding of global changes and regional patterns for over two decades. With more and more missions providing now also observations of causes such as water mass changes due to ice melt and land hydrology as well as the ocean heat and salinity budget and local and regional wind patterns, we can now get a comprehensive understanding of the physical processes causing the short to long term changes in sea level. Here, we present an overview of sea level observations in combination with a suite of measurements looking at sea level contributions to provide insight into current and future challenges to understand the sea level budget and its impact on the accuracy of future projections.

  6. Serum fucosyl transferase activity and serum fucose levels as diagnostic tools in malignancy.

    Sen,Umi

    1983-12-01

    Full Text Available Glycoproteins play a significant role in neoplastic transformations. Both the levels of fucose and the activity of fucosyl transferase, which mediates the assembly of the oligosaccharide moieties of the glycoprotein chains, have been found to be elevated in neoplastic conditions. Since these elevations are common features of a variety of neoplastic cells, these two have been designated as non-specific markers of malignancy. In the present study, the fucose level and fucosyl transferase activity were determined in the sera of cancer patients and an attempt was made to establish a relationship between the two. It was found that both the fucose levels and fucosyl transferase activities showed considerable elevation in the five cancer groups studied, establishing them as useful diagnostic parameters. However, it was also observed that the rate of increased fucosyl transferase activity was not fully reflected in the resulting serum fucose levels in a few cases.

  7. The Arctic Observing Viewer: A Web-mapping Application for U.S. Arctic Observing Activities

    Kassin, A.; Gaylord, A. G.; Manley, W. F.; Villarreal, S.; Tweedie, C. E.; Cody, R. P.; Copenhaver, W.; Dover, M.; Score, R.; Habermann, T.

    2014-12-01

    way will help to ensure improved capacities for conducting activities such as assessing the status of arctic observing efforts, optimizing logistic operations, and for quickly accessing external and project-focused web resources for more detailed information and data.

  8. Observational and model evidence for positive low-level cloud feedback.

    Clement, Amy C; Burgman, Robert; Norris, Joel R

    2009-07-24

    Feedbacks involving low-level clouds remain a primary cause of uncertainty in global climate model projections. This issue was addressed by examining changes in low-level clouds over the Northeast Pacific in observations and climate models. Decadal fluctuations were identified in multiple, independent cloud data sets, and changes in cloud cover appeared to be linked to changes in both local temperature structure and large-scale circulation. This observational analysis further indicated that clouds act as a positive feedback in this region on decadal time scales. The observed relationships between cloud cover and regional meteorological conditions provide a more complete way of testing the realism of the cloud simulation in current-generation climate models. The only model that passed this test simulated a reduction in cloud cover over much of the Pacific when greenhouse gases were increased, providing modeling evidence for a positive low-level cloud feedback. PMID:19628865

  9. Estimation of the neuronal activation using fMRI data: An observer-based approach

    Laleg-Kirati, Taous-Meriem

    2013-06-01

    This paper deals with the estimation of the neuronal activation and some unmeasured physiological information using the Blood Oxygenation Level Dependent (BOLD) signal measured using functional Magnetic Resonance Imaging (fMRI). We propose to use an observer-based approach applied to the balloon hemodynamic model. The latter describes the relation between the neural activity and the BOLD signal. The balloon model can be expressed in a nonlinear state-space representation where the states, the parameters and the input (neuronal activation), are unknown. This study focuses only on the estimation of the hidden states and the neuronal activation. The model is first linearized around the equilibrium and an observer is applied to this linearized version. Numerical results performed on synthetic data are presented.

  10. Active region upflows: 1. Multi-instrument observations

    Vanninathan, K; Galsgaard, K; Huang, Z; Doyle, J G

    2015-01-01

    Upflows at the edges of active regions (ARs) are studied by spatially and temporally combining multi-instrument observations obtained with EIS/Hinode, AIA and HMI/SDO and IBIS/NSO, to derive their plasma parameters. This information is used for benchmarking data-driven modelling of the upflows (Galsgaard et al., 2015). The studied AR upflow displays blueshifted emission of 5-20 km/s in Fe XII and Fe XIII and its average electron density is 1.8x10^9 cm^3 at 1 MK. The time variation of the density shows no significant change (in a 3sigma error). The plasma density along a single loop drops by 50% over a distance of 20000 km. We find a second velocity component in the blue wing of the Fe XII and Fe XIII lines at 105 km/s. This component is persistent during the whole observing period of 3.5 hours with variations of only 15 km/s. We also study the evolution of the photospheric magnetic field and find that magnetic flux diffusion is responsible for the formation of the upflow region. High cadence Halpha observatio...

  11. Observation of energetic radiation associated with winter thunderstorm activity

    The dose rate of the gamma-rays increases in association with the activities of the thunderstorm. They were observed on the ground in the winter season of Japan. To investigate the time profile of the radiations during the winter thunderstorms, the radiation detectors were prepared which consist of the long proportional counters. These detectors have different characteristics of the response for the energy of the incident particles by mounting different thick shielding covers. Those results were compared with the results measured at the same time by the environmental radiation monitors set up around a nuclear facility. Electric field was also measured by using a field mill. As a result, the following two types of the radiation enhancements have been found during the winter thunderstorm activities; the gradual variation of photon intensity with energy of a few MeV, and the burst type of the radiation that is attributed to the injection of high energy photons with the energy over 10 MeV. (author)

  12. Sea level variability in the Arctic Ocean observed by satellite altimetry

    P. Prandi; Ablain, M.; A. Cazenave; Picot, N.

    2012-01-01

    We investigate sea level variability in the Arctic Ocean from observations. Variability estimates are derived both at the basin scale and on smaller local spatial scales. The periods of the signals studied vary from high frequency (intra-annual) to long term trends. We also investigate the mechanisms responsible for the observed variability. Different data types are used, the main one being a recent reprocessing of satellite altimetry data...

  13. Sea Level Change for Norway: Past and Present Observations and Projections to 2100

    Simpson, Matthew; Øie Nilsen, Jan Even; Ravndal, Oda; Breili, Kristian; Sande, Hilde; Kierulf, Halfdan; Steffen, Holger; Jansen, Eystein; Carson, Mark; Vestol, Olav

    2016-04-01

    Changes to mean sea level and/or sea level extremes (e.g., storm surges) will lead to changes in coastal impacts. These changes represent a changing exposure or risk to our society. Here we try to synthesize our understanding of past and present observed sea level changes for Norway, as well as providing sea level projections up until 2100. Our primary focus is changes to mean sea level but we also give updated return heights for each coastal municipality in Norway. We first analyse observed sea level changes from the Norwegian tide gauge network and from satellite altimetry. After the tide gauge data have been corrected for the effects of glacial isostatic adjustment, we show that 20th century sea level rise in Norwegian waters is broadly similar to the global average rise. Contributions to the observed sea level change and variability are discussed. We find that rate of sea level rise along the Norwegian coast is significantly higher for the period 1993-2014 than for the period 1960-2010. It is unclear, however, to what extent this higher rate represents natural variability rather than a sustained increase owing to global warming. Our regional sea level projections are based on findings from the Fifth Assessment Report (AR5) of the Intergovernmental Panel for Climate Change (IPCC), and the Coupled Model Intercomparison Project phase 5 (CMIP5) output. Average projected 21st century relative sea level change in Norway is -0.10-0.35 m (5 to 95% model ranges which is the likely range in AR5; P>66%) for RCP2.6, -0.05-0.45 m for RCP4.5, and 0.10-0.65 m for RCP8.5. The relative sea level projections can differ as much as 0.50 m from place to place. This pattern is governed by the vertical uplift rates. Quantifying the probability of levels above the likely range (i.e., the upper tail of the probability distribution) remains difficult because information is lacking. And of particular concern is that the ice sheet contribution might have a skewed distribution, which would

  14. Low level laser therapy reduces inflammation in activated Achilles tendinitis

    Bjordal, Jan M.; Iversen, Vegard; Lopes-Martins, Rodrigo Alvaro B.

    2006-02-01

    Objective: Low level laser therapy (LLLT) has been forwarded as therapy for osteoarthritis and tendinopathy. Results in animal and cell studies suggest that LLLT may act through a biological mechanism of inflammatory modulation. The current study was designed to investigate if LLLT has an anti-inflammatory effect on activated tendinitis of the Achilles tendon. Methods: Seven patients with bilateral Achilles tendonitis (14 tendons) who had aggravated symptoms by pain-inducing activity immediately prior to the study. LLLT (1.8 Joules for each of three points along the Achilles tendon with 904nm infrared laser) and placebo LLLT were administered to either Achilles tendons in a random order to which patients and therapist were blinded. Inflammation was examined by 1) mini-invasive microdialysis for measuring the concentration of inflammatory marker PGE II in the peritendinous tissue, 2) ultrasound with Doppler measurement of peri- and intratendinous blood flow, 3) pressure pain algometry and 4) single hop test. Results: PGE 2- levels were significantly reduced at 75, 90 and 105 minutes after active LLLT compared both to pre-treatment levels (p=0.026) and to placebo LLLT (p=0.009). Changes in pressure pain threshold (PPT) were significantly different (P=0.012) between groups. PPT increased by a mean value of 0.19 kg/cm2 [95%CI:0.04 to 0.34] after treatment in the active LLLT group, while pressure pain threshold was reduced by -0.20 kg/cm2 [95%CI:-0.45 to 0.05] after placebo LLLT. Conclusion: LLLT can be used to reduce inflammatory musculskeletal pain as it reduces inflammation and increases pressure pain threshold levels in activity-induced pain episodes of Achilles tendinopathy.

  15. Physical activity level and sedentary time in Norwegian adolescents

    Sundgot-Borgen, Christine

    2013-01-01

    Background: Physical activity (PA) is necessary for children and adolescents to obtain a healthy development. The environment, however, facilitates the sedentary lifestyle. World health organization (WHO) defines physical inactivity as the fourth major risk factor for mortality. Still, adolescents in Europe and America are sedentary more than 50 % of their waking hours. Lack of comparability between studies investigating PA level and sedentary time in adolescents creates need f...

  16. The relationship between postnatal depression, sociodemographic factors, levels of partner support, and levels of physical activity

    Maryam eSaligeh

    2014-07-01

    Full Text Available Background: postnatal depression (PND is defined as a psychological mood disorder that occurs in a mother within six weeks of her giving birth. It refers to an episode that causes mood disturbance and it could begin in, or extend into, the postpartum period. It is thought to have a high impact upon the mother’s health as well as the family’s functioning and the child’s development. Socio-demographic, psych-social, and physical activity factors may all contribute to postpartum mood and ability to cope with responsibilities. The primary aim of this study was to determine which of these factors predicted PND in postpartum women. A secondary aim was to identify the socio-demographic and psycho-social predictors of physical activity in postpartum women . Methods: The study used a cross-sectional correlational design. A sample of 150 postpartum women was sent a package of six standardised questionnaires. Results: There was no association between physical activity and PND; however, older mothers, mothers of younger children, mothers who are less reluctant to ask for help, and mothers who are more satisfied with the help they get experience lower levels of PND. Mothers of older babies, mothers with more children, and less educated mothers are more likely to engage in caregiving activities, whereas mothers with fewer children and higher levels of partner support are more likely to engage in occupational activities. None of the socio-demographic factors or any of the parenting factors predicted levels of sporting activity.

  17. Estimation of nonfluctuating reservoir inflow from water level observations using methods based on flow continuity

    Deng, Chao; Liu, Pan; Guo, Shenglian; Wang, Hao; Wang, Dingbao

    2015-10-01

    The accurate estimation of "true" reservoir inflow is important for hydrological forecasting and efficient operation of reservoirs. However, reservoir inflow estimated using the conventional simple water balance method is not always accurate because the estimation is very sensitive to errors in reservoir water level observations and uncertainty in the stage-storage relationship. An analytical method (AM) and a method using the ensemble Kalman filter (EnKF) are proposed to determine nonfluctuating reservoir inflow based on the concept of inflow continuity; that is, that inflow should not change much within a short time period. The AM is developed based on the simultaneous minimization of both the estimated reservoir water level error and the inflow variation. The EnKF, which is built on state equations (inflow continuity and water balance equations) and an observation equation (the reservoir stage-storage relationship), is used to update inflow states by assimilating water level observations. The two proposed methods are evaluated using a synthetic experiment with various conditions including water level observation error, reservoir stage-storage relationship error, and the influence of water surface slope. The AM outperforms the EnKF under all conditions. Case studies of the Gaobazhou and Danjiangkou Reservoirs in China demonstrate that both of the proposed methods can derive an hourly inflow without fluctuations. The results indicate that the AM and the EnKF method can improve reservoir inflow estimation compared with conventional methods.

  18. Measuring Students' Physical Activity Levels: Validating SOFIT for Use with High-School Students

    van der Mars, Hans; Rowe, Paul J.; Schuldheisz, Joel M.; Fox, Susan

    2004-01-01

    This study was conducted to validate the System for Observing Fitness Instruction Time (SOFIT) for measuring physical activity levels of high-school students. Thirty-five students (21 girls and 14 boys from grades 9-12) completed a standardized protocol including lying, sitting, standing, walking, running, curl-ups, and push-ups. Heart rates and…

  19. Real-time Observational Water Level Data Stream Online Filtering Method with Hydrological Changes Semantic Constraints

    DING Yulin

    2015-12-01

    Full Text Available Irregular environmental changes and occasional instrument malfunctions have made noises and exceptions in observational data prominence. Therefore, before processing real-time water level data online, data cleaning is urgently needed to ensure data quality. Since traditional data filtering methods didn't take the data change pattern into consideration, these methods have encountered some severe problems, including the poor adaptability of filter model, the low estimation precision and prohibitively high calculation cost. To overcome these shortcomings, this paper presents a hydrological change semantics constrained online Kalman filtering method: creating dynamic semantic mapping between real-time data changing pattern and the rules of spatial-temporal hydrological process evolution; implementing the change semantic constrained Kalman filtering method to support the adaptive parameter optimization. Observational water level data streams of different precipitation scenarios are selected for testing. Experimental results prove that by means of this method, more accurate and reliable water level information can be available.

  20. TETRA Observation of Gamma Rays at Ground Level Associated with Nearby Thunderstorms

    Ringuette, Rebecca; Cherry, Michael L; Granger, Douglas; Guzik, T Gregory; Stewart, Michael; Wefel, John P

    2013-01-01

    Terrestrial Gamma ray Flashes (TGFs) -- very short, intense bursts of electrons, positrons, and energetic photons originating from terrestrial thunderstorms -- have been detected with satellite instruments. TETRA, an array of NaI(Tl) scintillators at Louisiana State University, has now been used to detect similar bursts of 50 keV to over 2 MeV gamma rays at ground level. After 2.6 years of observation, twenty-four events with durations 0.02- 4.2 msec have been detected associated with nearby lightning, three of them coincident events observed by detectors separated by ~1000 m. Nine of the events occurred within 6 msec and 3 miles of negative polarity cloud-to-ground lightning strokes with measured currents in excess of 20 kA. The events reported here constitute the first catalog of TGFs observed at ground level in close proximity to the acceleration site.

  1. Observation level combination of SLR and VLBI with c5++: A case study for TIGO

    Hobiger, Thomas; Otsubo, Toshimichi; Sekido, Mamoru

    2014-01-01

    A multi-technique space geodetic analysis software named c5++ has been developed and allows one to combine data on the observation level. With SLR and VLBI modules being ready and tested, this software has been used to compute coordinate time series of the geodetic fundamental station TIGO, located near Concepción, Chile. It can be shown that the combination of space geodetic data on the observation level leads to a significant improvement of station position repeatability, which is an important measure for the stability of a station in the terrestrial reference frame. Moreover, it could be demonstrated that the geophysical signal of the post-seismic tectonic plate movement is usually more complete than detected by any of the two single-technique solutions. In addition, it has been confirmed that so-called nuisance parameters, which are relying on data from a single technique, are not biased when combing observations from different space geodetic techniques.

  2. Irisin Levels are Not Affected by Physical Activity in Patients with Anorexia Nervosa

    Tobias eHofmann; Ulf eElbelt; Anne eAhnis; Peter eKobelt; Matthias eRose; Andreas eStengel

    2014-01-01

    Irisin was recently identified as muscle-derived hormone that increases energy expenditure. Studies in normal weight and obese subjects reported an increased irisin expression following physical activity, although inconsistent results were observed. Increased physical activity in a subgroup of patients with anorexia nervosa (AN) complicates the course of the disease. Since irisin could account for differences in clinical outcomes, we investigated irisin levels in anorexic patients with high a...

  3. Secular trends in storm-level geomagnetic activity

    J. J. Love

    2011-02-01

    Full Text Available Analysis is made of K-index data from groups of ground-based geomagnetic observatories in Germany, Britain, and Australia, 1868.0–2009.0, solar cycles 11–23. Methods include nonparametric measures of trends and statistical significance used by the hydrological and climatological research communities. Among the three observatory groups, German K data systematically record the highest disturbance levels, followed by the British and, then, the Australian data. Signals consistently seen in K data from all three observatory groups can be reasonably interpreted as physically meaninginful: (1 geomagnetic activity has generally increased over the past 141 years. However, the detailed secular evolution of geomagnetic activity is not well characterized by either a linear trend nor, even, a monotonic trend. Therefore, simple, phenomenological extrapolations of past trends in solar and geomagnetic activity levels are unlikely to be useful for making quantitative predictions of future trends lasting longer than a solar cycle or so. (2 The well-known tendency for magnetic storms to occur during the declining phase of a sunspot-solar cycles is clearly seen for cycles 14–23; it is not, however, clearly seen for cycles 11–13. Therefore, in addition to an increase in geomagnetic activity, the nature of solar-terrestrial interaction has also apparently changed over the past 141 years.

  4. Using observation-level random effects to model overdispersion in count data in ecology and evolution

    Xavier A. Harrison

    2014-10-01

    Full Text Available Overdispersion is common in models of count data in ecology and evolutionary biology, and can occur due to missing covariates, non-independent (aggregated data, or an excess frequency of zeroes (zero-inflation. Accounting for overdispersion in such models is vital, as failing to do so can lead to biased parameter estimates, and false conclusions regarding hypotheses of interest. Observation-level random effects (OLRE, where each data point receives a unique level of a random effect that models the extra-Poisson variation present in the data, are commonly employed to cope with overdispersion in count data. However studies investigating the efficacy of observation-level random effects as a means to deal with overdispersion are scarce. Here I use simulations to show that in cases where overdispersion is caused by random extra-Poisson noise, or aggregation in the count data, observation-level random effects yield more accurate parameter estimates compared to when overdispersion is simply ignored. Conversely, OLRE fail to reduce bias in zero-inflated data, and in some cases increase bias at high levels of overdispersion. There was a positive relationship between the magnitude of overdispersion and the degree of bias in parameter estimates. Critically, the simulations reveal that failing to account for overdispersion in mixed models can erroneously inflate measures of explained variance (r2, which may lead to researchers overestimating the predictive power of variables of interest. This work suggests use of observation-level random effects provides a simple and robust means to account for overdispersion in count data, but also that their ability to minimise bias is not uniform across all types of overdispersion and must be applied judiciously.

  5. Altered cortical activation during action observation in amyotrophic lateral sclerosis patients: a parametric functional MRI study

    Li, Haiqing; Li, Yuxin; Yin, Bo; Tang, Weijun; Yu, Xiangrong; Geng, Daoying [Huashan Hospital, Department of Radiology, Fudan University, Shanghai (China); Chen, Yan [Fudan University, Department of Neurology, Huashan Hospital, Shanghai (China); Huang, Weiyuan [People' s Hospital of Hainan Province, Department of Radiology, Haikou, Hainan Province (China); Zhang, Biyun [Nanjing University of Traditional Chinese Medicine, Department of radiotherapy, Affiliated Jiangsu Province Hospital of Traditional Chinese Medicine, Nanjing (China)

    2015-09-15

    To investigate functional cerebral abnormalities in patients with amyotrophic lateral sclerosis (ALS) using functional magnetic resonance imaging (fMRI) during action observation. Thirty patients with ALS and 30 matched healthy controls underwent fMRI with an experimental paradigm while observing a video of repetitive flexion-extension of the fingers at three frequency levels or three complexity levels, alternated with periods of a static hand. A parametric analysis was applied to determine the effects of each of the two factors. Action observation activated similar neural networks as the research on execution of action in the ALS patients and healthy subjects in several brain regions related to the mirror-neuron system (MNS). In the ALS patients, in particular, the dorsal lateral premotor cortex (dPMC), inferior parietal gyrus (IPG), and SMA, were more activated compared with the activation in the controls. Increased activation within the primary motor cortex (M1), dPMC, inferior frontal gyrus (IFG), and superior parietal gyrus (SPG) mainly correlated with hand movement frequency/complexity in the videos in the patients compared with controls. The findings indicated an ongoing compensatory process occurring within the higher order motor-processing system of ALS patients, likely to overcome the loss of function. (orig.)

  6. Altered cortical activation during action observation in amyotrophic lateral sclerosis patients: a parametric functional MRI study

    To investigate functional cerebral abnormalities in patients with amyotrophic lateral sclerosis (ALS) using functional magnetic resonance imaging (fMRI) during action observation. Thirty patients with ALS and 30 matched healthy controls underwent fMRI with an experimental paradigm while observing a video of repetitive flexion-extension of the fingers at three frequency levels or three complexity levels, alternated with periods of a static hand. A parametric analysis was applied to determine the effects of each of the two factors. Action observation activated similar neural networks as the research on execution of action in the ALS patients and healthy subjects in several brain regions related to the mirror-neuron system (MNS). In the ALS patients, in particular, the dorsal lateral premotor cortex (dPMC), inferior parietal gyrus (IPG), and SMA, were more activated compared with the activation in the controls. Increased activation within the primary motor cortex (M1), dPMC, inferior frontal gyrus (IFG), and superior parietal gyrus (SPG) mainly correlated with hand movement frequency/complexity in the videos in the patients compared with controls. The findings indicated an ongoing compensatory process occurring within the higher order motor-processing system of ALS patients, likely to overcome the loss of function. (orig.)

  7. Estimation of Missing Observations in Two-Level Split-Plot Designs

    Almimi, Ashraf A.; Kulahci, Murat; Montgomery, Douglas C.

    2008-01-01

    Inserting estimates for the missing observations from split-plot designs restores their balanced or orthogonal structure and alleviates the difficulties in the statistical analysis. In this article, we extend a method due to Draper and Stoneman to estimate the missing observations from unreplicated...... two-level factorial and fractional factorial split-plot (FSP and FFSP) designs. The missing observations, which can either be from the same whole plot, from different whole plots, or comprise entire whole plots, are estimated by equating to zero a number of specific contrast columns equal to the...... number of the missing observations. These estimates are inserted into the design table and the estimates for the remaining effects (or alias chains of effects as the case with FFSP designs) are plotted on two half-normal plots: one for the whole-plot effects and the other for the subplot effects. If the...

  8. Research Note: Physical Activity Levels in Elementary-School Physical Education: A Comparison of Swimming and Nonswimming Classes

    Cardon, Greet; Verstraete, Stefanie; De Clercq, Dirk; De Bourdeaudhuij, Ilse

    2004-01-01

    The main goal of the current study was to compare physical activity levels during swimming and nonswimming elementary physical education classes. We conducted a preliminary study and found that the System for Observing Fitness Instruction Time (SOFIT) could be used to register physical activity engagement levels in swimming classes. Thirty-nine…

  9. Contamination levels observed on the Belgian territory subsequent to the Chernobyl accident

    A summary of the data from different laboratories concerning the fallout on the Belgian territory following the Chernobyl emissions is presented. The evolution of the particulate air activity at ground level, the integrated fallout captured in water, the deposition on soil surface directly for different localities in Belgium are given. The grass contamination, the milk contamination from individual farms, the concentration levels on leafy vegetables, surface waters and water basins and the contamination of meat during the month of May are presented. (A.F.)

  10. Magnetoseismology of Active Regions using Multi-wavelength Observations from GONG and SDO

    Tripathy, Sushanta; Jain, Kiran; Kholikov, Shukur; Hill, Frank; Cally, Paul

    2016-05-01

    The structure and dynamics of active regions beneath the surface show significant uncertainties due to our limited understanding of the wave interaction with magnetic field. Recent numerical simulations further demonstrate that the atmosphere above the photospheric levels also modifies the seismic observables at the surface. Thus the key to improve helioseismic interpretation beneath the active regions requires a synergy between models and helioseismic inferences from observations. In this context, using data from Global Oscillation Network Group and from Helioseismic Magnetic Imager and Atmospheric Imaging Assembly onboard Solar Dynamics Observatory, we characterize the spatio-temporal power distribution in and around active regions. Specifically, we focus on the power enhancements seen around active regions as a function of wave frequencies, strength, inclination of magnetic field and observation height as well as the relative phases of the observables and their cross-coherence functions. It is expected that these effects will help us to comprehend the interaction of acoustic waves with magnetic field in the solar photosphere.

  11. Acetylcholinesterase Modulates Presenilin-1 Levels and γ-Secretase Activity

    Campanari, María-Letizia; García Ayllón, María Salud; Belbin, Olivia; Galcerán, Joan; Lleó, Alberto; Sáez-Valero, Javier

    2014-01-01

    The cholinergic enzyme acetylcholinesterase (AChE) and the catalytic component of the ¿-secretase complex, presenilin-1 (PS1), are known to interact. In this study, we investigate the consequences of AChE-PS1 interactions, particularly the influence of AChE in PS1 levels and ¿-secretase activity. PS1 is able to co-immunoprecipitate all AChE variants (AChE-R and AChE-T) and molecular forms (tetramers and light subunits) present in the human brain. Overexpression of AChE-R or AChE-T, or their r...

  12. Human monoamine oxidase A gene determines levels of enzyme activity.

    Hotamisligil, G S; Breakefield, X O

    1991-01-01

    Monoamine oxidase (MAO) is a critical enzyme in the degradative deamination of biogenic amines throughout the body. Two biochemically distinct forms of the enzyme, A and B, are encoded in separate genes on the human X chromosome. In these studies we investigated the role of the structural gene for MAO-A in determining levels of activity in humans, as measured in cultured skin fibroblasts. The coding sequence of the mRNA for MAO-A was determined by first-strand cDNA synthesis, PCR amplificatio...

  13. Scheduling satellite-based SAR acquisition for sequential assimilation of water level observations into flood modelling

    Garcia-Pintado, Javier; Neal, Jeff; Mason, David,; Dance, Sarah; Bates, Paul

    2013-01-01

    Satellite-based Synthetic Aperture Radar (SAR) has proved useful for obtaining information on flood extent, which, when intersected with a Digital Elevation Model (DEM) of the floodplain, provides water level observations that can be assimilated into a hydrodynamic model to decrease forecast uncertainty. With an increasing number of operational satellites with SAR capability, information on the relationship between satellite first visit and revisit times and forecast performance is required t...

  14. Observation of a single spin by transferring its coherence to a high level macroscopic pure state

    Kawamura, Minaru [Electrical and Electronic Engineering, Okayama University of Science, 1-1 Ridai-cho, kita-ku, Okayama, 700-0005 (Japan)

    2014-12-04

    We discuss about quantum measurement of a single spin in a superconducting RF resonator, where amplification of coherence of the spin is enabled by transferring its coherence to the harmonic oscillator in an non-coherent state with high energy level. This quantum amplification allows that a single spin can induce macroscopic current to permits observation of a single spin state in the number and phase uncertainty relation.

  15. Tropical Pacific spatial trend patterns in observed sea level: internal variability and/or anthropogenic signature?

    B. Meyssignac

    2012-04-01

    Full Text Available In this study we focus on the sea level trend pattern observed by satellite altimetry in the tropical Pacific over the 1993–2009 time span (i.e. 17 yr. Our objective is to investigate whether this 17-yr-long trend pattern was different before the altimetry era, what was its spatio-temporal variability and what have been its main drivers. We try to discriminate the respective roles of the internal variability of the climate system and of external forcing factors, in particular anthropogenic emissions (greenhouse gases and aerosols. On the basis of a 2-D past sea level reconstruction over 1950–2009 (based on a combination of observations and ocean modelling and multi-century control runs (i.e. with constant, preindustrial external forcing from eight coupled climate models, we have investigated how the observed 17-yr sea level trend pattern evolved during the last decades and centuries, and try to estimate the characteristic time scales of its variability. For that purpose, we have computed sea level trend patterns over successive 17-yr windows (i.e. the length of the altimetry record, both for the 60-yr long reconstructed sea level and the model runs. We find that the 2-D sea level reconstruction shows spatial trend patterns similar to the one observed during the altimetry era. The pattern appears to have fluctuated with time with a characteristic time scale of the order of 25–30 yr. The same behaviour is found in multi-centennial control runs of the coupled climate models. A similar analysis is performed with 20th century coupled climate model runs with complete external forcing (i.e. solar plus volcanic variability and changes in anthropogenic forcing. Results suggest that in the tropical Pacific, sea level trend fluctuations are dominated by the internal variability of the ocean–atmosphere coupled system. While our analysis cannot rule out any influence of anthropogenic forcing, it concludes that the latter effect in that particular

  16. Greenland uplift and regional sea level changes from ICESat observations and GIA modelling

    Spada, G.; Ruggieri, G.; Sørensen, Louise Sandberg;

    2012-01-01

    response to current ice mass loss, which is not resolved by satellite gravity observations, we have specifically developed a high‐resolution regional elastic rebound (ER) model. The elastic component of vertical uplift is combined with estimates of the viscoelastic displacement fields associated with the......‐resolution GrIS mass balance, we study the time‐variations of various geophysical quantities in response to the current mass loss. They include vertical uplift and subsidence, geoid height variations, global patterns of sea level change (or fingerprints), and regional sea level variations along the coasts of...... Greenland. Long‐wavelength uplifts and gravity variations in response to current or past ice thickness variations are obtained solving the sea level equation, which accounts for both the elastic and the viscoelastic components of deformation. To capture the short‐wavelength components of vertical uplift in...

  17. Evaluation of high-level clouds in cloud resolving model simulations with ARM and KWAJEX observations

    Liu, Zheng; Muhlbauer, Andreas; Ackerman, Thomas

    2015-12-01

    In this study, we evaluate high-level clouds in a cloud resolving model during two convective cases, ARM9707 and KWAJEX. The simulated joint histograms of cloud occurrence and radar reflectivity compare well with cloud radar and satellite observations when using a two-moment microphysics scheme. However, simulations performed with a single moment microphysical scheme exhibit low biases of approximately 20 dB. During convective events, two-moment microphysical overestimate the amount of high-level cloud and one-moment microphysics precipitate too readily and underestimate the amount and height of high-level cloud. For ARM9707, persistent large positive biases in high-level cloud are found, which are not sensitive to changes in ice particle fall velocity and ice nuclei number concentration in the two-moment microphysics. These biases are caused by biases in large-scale forcing and maintained by the periodic lateral boundary conditions. The combined effects include significant biases in high-level cloud amount, radiation, and high sensitivity of cloud amount to nudging time scale in both convective cases. The high sensitivity of high-level cloud amount to the thermodynamic nudging time scale suggests that thermodynamic nudging can be a powerful "tuning" parameter for the simulated cloud and radiation but should be applied with caution. The role of the periodic lateral boundary conditions in reinforcing the biases in cloud and radiation suggests that reducing the uncertainty in the large-scale forcing in high levels is important for similar convective cases and has far reaching implications for simulating high-level clouds in super-parameterized global climate models such as the multiscale modeling framework.

  18. Modeling hyperspectral observations of vegetation fluorescence from photosystem level to top-of-atmosphere radiance spectra

    Verhoef, W.

    2011-12-01

    In support of the candidate ESA mission FLEX, models have been developed to simulate vegetation chlorophyll fluorescence and its observation on the level of single leaves, the canopy and from space. The Fluspect model is based on the PROSPECT leaf model and includes an additional module which calculates the excitation-fluorescence matrix for both sides of the leaf by means of an efficient doubling algorithm. Fluorescence spectra for white incident light, and of course the spectra of reflectance and transmittance, are computed as well. The FluorSAIL model is a numerical variant of SAIL which calculates top-of-canopy fluorescent radiance in the direction of viewing for given incident radiation spectra from the sun and the sky, obtained from the MODTRAN radiative transfer code. In a recent version called FluorSAIL3, high spectral resolution data (0.1 nm) from MODTRAN5 (beta) are used by the model to simulate observations by the candidate FLEX mission. The model computes the directional canopy reflectance with and without fluorescence for the given incident radiation spectra obtained from MODTRAN and the results have been used to evaluate several algorithms for the retrieval of fluorescence from the apparent reflectance signal. In this contribution emphasis will be on the detection of the fluorescence signal, the dependence of fluorescence observations on leaf chlorophyll content and other PROSPECT parameters, canopy structure, and observational conditions, including the properties of the atmosphere. In addition, some attention is paid to the definition of fluorescence quantum efficiencies at photosystem level, leaf level, and canopy level. This is important for the study of the relation between canopy fluorescence and actual photosynthesis. From the simulations it can be concluded that the interpretation of the fluorescence signal is complex, and probably the comparison of actual observations of spectra of fluorescence and reflectance with spectra simulated by a

  19. Observation of deep levels and their hole capture behavior in p-type 4H-SiC epilayers with and without electron irradiation

    To design SiC bipolar devices, information on deep levels acting as recombination centers is essential. In this paper, we report on the observation of deep levels in p-type 4H-SiC epilayers with and without electron irradiation before and after annealing at 1000 °C. We performed current deep level transient spectroscopy (I-DLTS) for the samples, and the observed deep levels were located near the valence band (with the activation energies less than 0.35 eV) in all the samples. Based on the change of I-DLTS spectra by the electron irradiation or the annealing, we discussed the origins of the deep levels. Then we estimated the time constants of hole capture by the deep levels and discussed the possibility that the observed deep levels behave as recombination centers. (author)

  20. Global Night-Time Lights for Observing Human Activity

    Hipskind, Stephen R.; Elvidge, Chris; Gurney, K.; Imhoff, Mark; Bounoua, Lahouari; Sheffner, Edwin; Nemani, Ramakrishna R.; Pettit, Donald R.; Fischer, Marc

    2011-01-01

    We present a concept for a small satellite mission to make systematic, global observations of night-time lights with spatial resolution suitable for discerning the extent, type and density of human settlements. The observations will also allow better understanding of fine scale fossil fuel CO2 emission distribution. The NASA Earth Science Decadal Survey recommends more focus on direct observations of human influence on the Earth system. The most dramatic and compelling observations of human presence on the Earth are the night light observations taken by the Defence Meteorological System Program (DMSP) Operational Linescan System (OLS). Beyond delineating the footprint of human presence, night light data, when assembled and evaluated with complementary data sets, can determine the fine scale spatial distribution of global fossil fuel CO2 emissions. Understanding fossil fuel carbon emissions is critical to understanding the entire carbon cycle, and especially the carbon exchange between terrestrial and oceanic systems.

  1. Magnetic field structures of solar active regions obtained by polarization mapping observation at 32 GHz

    Solar radio polarization mapping observation was made at 32 GHz with an angular resolution of 3.' 6 on February 2 and 4, 1981. The polarization map represents the distribution of the difference between right-handed (R) and left-handed (L) circular polarization components on the sun (R-L). The polarization maps of two days showed that four active regions on the sun had clear bipolar structures, which were consistent with those observed on the magnetograms. The peak value of the circular polarization degree in the active regions lay between 0.4 % and 2.5 %, which suggests that the longitudinal magnetic field strength at the chromospheric level was between 20 G and 140 G. (author)

  2. Observed mean sea level changes around the North Sea coastline from 1800 to present

    Wahl, T.; Haigh, I. D.; Woodworth, P. L.; Albrecht, F.; Dillingh, D.; Jensen, J.; Nicholls, R. J.; Weisse, R.; Wöppelmann, G.

    2013-09-01

    This paper assesses historic changes in mean sea level around the coastline of the North Sea, one of the most densely populated coasts in the world. Typically, such analyses have been conducted at a national level, and detailed geographically wider analyses have not been undertaken for about 20 years. We analyse long records (up to 200 years) from 30 tide gauge sites, which are reasonably uniformly distributed along the coastline, and: (1) calculate relative sea level trends; (2) examine the inter-annual and decadal variations; (3) estimate regional geocentric (sometimes also referred to as 'absolute') sea level rise throughout the 20th century; and (4) assess the evidence for regional acceleration of sea-level rise. Relative sea level changes are broadly consistent with known vertical land movement patterns. The inter-annual and decadal variability is partly coherent across the region, but with some differences between the Inner North Sea and the English Channel. Data sets from various sources are used to provide estimates of the geocentric sea level changes. The long-term geocentric mean sea level trend for the 1900 to 2011 period is estimated to be 1.5 ± 0.1 mm/yr for the entire North Sea region. The trend is slightly higher for the Inner North Sea (i.e. 1.6 ± 0.1 mm/yr), and smaller but not significantly different on the 95% confidence level for the English Channel (i.e. 1.2 ± 0.1 mm/yr). The uncertainties in the estimates of vertical land movement rates are still large, and the results from a broad range of approaches for determining these rates are not consistent. Periods of sea level rise acceleration are detected at different times throughout the last 200 years and are to some extent related to air pressure variations. The recent rates of sea level rise (i.e. over the last two to three decades) are high compared to the long-term average, but are comparable to those which have been observed at other times in the late 19th and 20th century.

  3. WD 1145+017 Photometric Observations During 8 Months of High Activity

    Gary, B L; Kaye, T G; Alonso, R; Hambsch, F -J

    2016-01-01

    WD 1145+017 was observed from 2015 November to 2016 July for the purpose of characterizing transit behavior of the white dwarf by dust clouds thought to be produced by fragments of an asteroid in close orbit with the star. Fortuitously, most of these observations were carried out during a time when the overall "dip" activity was dramatically enhanced over that during its discovery with K2. By the end of our reported observations the dip activity had declined to a level close to its original state. Three notable events were observed. In 2016 January a large number of dust clouds appeared that had an orbital period of 4.4912 hours, and this event also marked the end of a 3-month interval of individual dip appearances that were dominated by short-lived activity producing an apparent 4.5004-hour periodicity that previous studies associated with the Kepler K2 "A" period. The second event was a 2016 April 21 appearance of four dip features with drift lines in a waterfall (date vs. phase) diagram that diverged from ...

  4. Using Aoristic Analysis to Link Remote and Ground-Level Phenological Observations

    Henebry, G. M.

    2013-12-01

    Phenology is about observing events in time and space. With the advent of publically accessible geospatial datastreams and easy to use mapping software, specifying where an event occurs is much less of a challenge than it was just two decades ago. In contrast, specifying when an event occurs remains a nontrivial function of a population of organismal responses, sampling interval, compositing period, and reporting precision. I explore how aoristic analysis can be used to analyzing spatiotemporal events for which the location is known to acceptable levels of precision but for which temporal coordinates are poorly specified or only partially bounded. Aoristic analysis was developed in the late 1990s in the field of quantitative criminology to leverage temporally imprecise geospatial data of crime reports. Here I demonstrate how aoristic analysis can be used to link remotely sensed observations of land surface phenology to ground-level observations of organismal phenophase transitions. Explicit representation of the windows of temporal uncertainty with aoristic weights enables cross-validation exercises and forecasting efforts to avoid false precision.

  5. Adhesion molecules levels in blood correlate with MRI activity and clinical activity in multiple sclerosis

    Research into pathogenesis of multiple sclerosis (MS) has prompted efforts to identify immunological markers associated with disease activity. Adhesion molecules ICAM-1 and VCAM-1 are associated with inflammatory mediated blood-brain barrier (BBB) dysfunction. In this study investigates the correlation between blood level of circulating ICAM-1 and VCAM-1 and magnetic resonance imaging (MRI) activity in different clinical phases of patients with MS. We show that RRMS and SPMS patients in clinically active phase with Gd-enhancing lesions in CNS had higher blood levels of cICAM-1 and cVCAM-1 compared these parameters levers of RRMS patients in remission stage. These results suggest that cICAM-1 and cVCAM-1 is a sensitive indicator of disease activity associated with BBB inflammatory dysfunction. Elevated blood level of cICAM-1 more strongly correlated with clinical activity and BBB damage, than cVCAM-1 and that could be used as biological marker of disease activity. Circulating VCAM-1 as an early indicator of BBB disturbance, may also serve as marker of beneficial activity in relapses phase of MS course. (authors)

  6. Oxidative DNA damage levels and catalase activity in the clam Ruditapes decussatus as pollution biomarkers of Tunisian marine environment.

    Jebali, Jamel; Banni, Mohamed; de Almeida, Eduardo Alves; Boussetta, Hamadi

    2007-01-01

    Levels of the oxidative DNA damage 7, 8-dihydro-8-oxo-2'-deoxyguanosine (8-oxodG) and catalase (CAT) activity were measured in the digestive gland and gills of clams Ruditapes decussatus, related to the presence of pollutants along Tunisian marine environment. Increased levels of CAT were observed in tissues of clams from all the sites studied, compared to control values, and elevated 8-oxodG levels were observed at specific sites. Results obtained in this work indicate that the measurement of 8-oxodG levels and CAT activity in tissues of R. decussatus is promising in pollution monitoring studies of the Tunisian marine environment. PMID:16897518

  7. Cassini Observes the Active South Pole of Enceladus

    Porco, C. C.; Helfenstein P.; Thomas, P. C.; Ingersoll, A. P.; Wisdom, J.; West, R.; Neukum, G.; Denk, T.; Wagner, R.; Roatsch, T.; Kieffer, S.; Turtle, E.; McEwen, A.; Johnson, T. V.; Rathbun, J.; Veverka, J.; Wilson, D.; Perry, J.; Spitale, J.; Brahic, A.; Burns, J. A.; DelGenio, A. D.; Dones, L.; Murray, C. D.; Squyres, S.

    2007-01-01

    Cassini has identified a geologically active province a the south pole of Saturn's moon Enceladus. The shape of Enceladus suggests a possible intense heating epoch in the past by capture into a 1:4 secondary spin/orbit resonance.

  8. Raised serum level of APRIL in patients with systemic lupus erythematosus: correlations with disease activity indices.

    Hegazy, M; Darwish, H; Darweesh, H; El-Shehaby, A; Emad, Y

    2010-04-01

    The aim of the present study is to assess serum APRIL levels in SLE patients versus rheumatoid arthritis (RA) patients and normal control and to correlate serum APRIL levels in SLE patients with disease activity indices. Serum APRIL levels was measured in 40 SLE patients, 20 patients with RA and 20 healthy volunteers who served as control group. Disease activity in SLE patients was assessed by the British Isles Lupus Assessment Group (BILAG) index and SLE disease activity index (SLEDAI), and results were correlated with serum APRIL levels. Significantly higher serum APRIL levels was observed in SLE patients compared to RA patients and normal controls (p=0.003 and p < or = 0.001, respectively). Positive correlations were found between serum APRIL levels and total BILAG index (r=0.486 and p=0.001), BILAG musculoskeletal score (r=0.848 and p < or = 0.001) and BILAG cardiorespiratory score (r=0.326 and 0.04). Serum APRIL was higher in SLE patients compared to RA patients and normal control subjects and positively correlates with BILAG index and higher levels may be associated with musculoskeletal manifestations of the disease. APRIL antagonism could be a potential therapeutic target in SLE. PMID:20116334

  9. Idaho Senior Center Activities, Activity Participation Level, and Managers' Perceptions of Activity Success.

    Girvan, James T.; Harris, Frances

    A survey completed by managers of 77 senior centers in Idaho revealed that meals, blood pressure screening, and games and trips were the most successful activities offered. Alzheimer's support groups, library books for loan, and exercise classes were the least successful. Possible reasons for the success or failure of these activities were…

  10. Levels of black carbon and their relationship with particle number levels-observation at an urban roadside in Taipei City.

    Cheng, Yu-Hsiang; Shiu, Ben-Tzung; Lin, Meng-Hsien; Yan, Jhih-Wei

    2013-03-01

    Information on the relationship between black carbon (BC) and particle number levels in urban areas is limited. Therefore, investigating the relationship between BC and particle number levels in different particle size ranges at an urban area is worthwhile. This study used an aethalometer and scanning mobility particle sizer to measure the levels of BC and particle number simultaneously at an urban roadside in Taipei City. Measurement results show that hourly BC levels are 0.62-8.80 μg m(-3) (mean=3.50 μg m(-3)) and hourly particle number levels are 4.21 × 10(3)-4.64 × 10(4) particles cm(-3) (mean=2.00 × 10(4) particles cm(-3)) in Taipei urban area. The BC and particle number levels peak during morning (7:00-9:00) and evening (16:00-18:00) rush hours on weekdays. Low BC and particle number levels exist in the early morning hours. Time variations in BC levels are the same as those of particle number levels in this study, clearly indicating that BC and particles are likely released from the same emission source. Additionally, BC levels in the urban area are more strongly associated with ultrafine particle levels than with total particle number levels, particularly in the size range of 56-180 nm. According to measurement results, most BC in aerosols in urban areas can be in the ultrafine size range. PMID:22798147

  11. Experimental observation of surface states and Landau levels bending in bilayer graphene

    Yin, Long-Jing; Zhang, Yu; Qiao, Jia-Bin; Li, Si-Yu; He, Lin

    2016-03-01

    We report on microscopic measurements of the low-energy electronic structures both at the zigzag and armchair edges of bilayer graphene using scanning tunneling microscopy and spectroscopy (STM and STS). We have found that, both in the absence and in the presence of a magnetic field, an almost zero-energy peak in the density of states was localized at the zigzag edges, as expected for the surface states at the zigzag edges of bilayer graphene. In the quantum Hall regime, we have clearly observed Landau levels bending away from the charge neutrality point near both the zigzag and armchair edges. Such a result is direct evidence for the evolution of Landau levels into quantum Hall edge states in graphene bilayers. Our experiment indicates that it is possible to explore rich quantum Hall physics in graphene systems using STM and STS.

  12. Observation of Deeply-Bound 85 Rb2 Vibrational Levels Using Feshbach Optimized Photoassociation

    Krzyzewski, Sean; Akin, Tom; Dizikes, James; Morrison, Michael; Abraham, Eric

    2016-05-01

    We demonstrate Feshbach optimized photoassociation (FOPA) into the 0g-(5 S1/2 + 5 P1/2) state in 85 Rb2. FOPA uses the enhancement of the amplitude of the initial atomic scattering wave function due to a Feshbach resonance to increase the molecular formation rate from photoassociation. We observe three vibrational levels, v = 127 , 140, and 150, with previously unmeasured binding energies of 256, 154, and 96 cm-1. We measure the frequency, central magnetic field position, and magnetic field width of each Feshbach resonance. Our findings experimentally confirm that this technique can measure vibrational levels lower than those accessible to traditional photoassociative spectroscopy. We present theory concerning the polarization dependence of FOPA for this system, and discuss implications of using this system to measure the time-variation of the electron/proton mass ratio.

  13. Observation of Ground Level Muon at Bangi In 2008-2009

    Zain, N. M.; Gopir, G.; Yatim, B.; Sanusi, H.; Husain, N. H.

    2010-07-01

    This study is carried out to observe muons coming from the zenith direction at ground level using a muon telescope based on Geiger-Muller (GM) tubes. Measurements were made for 16 sampling days from November 2008 to January 2009; simultaneously outside and inside the Physics Building of Universiti Kebangsaan Malaysia in Bangi (3.05edeg N, 101.68° E and 50 m asl), Malaysia. Daily sampling sessions of 30 minutes are sub-divided into six consecutive sub-sampling periods of five minutes and descriptive statistics is used to summarise the observed muon counts. Then, applying the inferential statistical methods of ANOVA and t-test indicate that the time variation of the muon count is not significant and the building roof does not significantly affect the muon count rate.

  14. TSUNAMI HAZARD MITIGATION AND THE NOAA NATIONAL WATER LEVEL OBSERVATION NETWORK

    James R. Hubbard

    2002-01-01

    Full Text Available With the renewed interest in regional Tsunami Warning Systems and the potential tsunami threats throughout the Caribbean and West coast of the United States, the National Ocean Service (NOS, National Water Level Observation Network (NWLON consisting of 175 primary stations, is well situated to play a role in the National Hazard Mitigation effort. In addition, information regarding local mean sea level trends and GPS derived geodetic datum relationships at numerous coastal locations is readily available for tsunami hazard assessment and mapping applications.Tsunami inundation maps and modeling are just two of the more important products which may be derived from NWLON data. In addition to the seven water level gauges that are hardwired into the West Coast and Alaska Tsunami Warning Center (WClATWC, NOS has a significant number of gauges with real-time satellite telemetry capabilities located along the Pacific Northwest coastline, the Gulf of Mexico and the Caribbean. These gauges, in concert with near shore buoy systems, have the potential for increasing the effectiveness of the existing tsunami warning system.The recent expansion of the Caribbean Sea Level Gauge Network through the NOS regional partnerships with Central American and Caribbean countries have opened an opportunity for a basin-wide tsunami warning network in a region which is ill prepared for a major tsunami event.

  15. Associations of group level popularity with observed behavior and influence in a dyadic context.

    Lansu, Tessa A M; Cillessen, Antonius H N

    2015-12-01

    This study examined the association between popularity in the peer group and adolescents' behavior in a dyadic context. After collecting peer nominations for popularity, 218 early adolescents (M(age) = 11.0 years) in 109 randomly composed same-sex dyads participated in a discussion task where they planned a party for their classroom. From digital recordings of the sessions, each participant's influence, involvement, skillful leadership, coercive resource control, submissiveness, positivity, and negativity were observed. Analyses with the actor-partner interdependence model (APIM) demonstrated that for girls high group level popularity was associated with a socially sensitive interaction style and influence in the dyadic context. For both boys and girls, the interaction partner's group level popularity negatively predicted their use of coercive resource control strategies and negative behavior in the dyad. For girls, in addition, the interaction partner's group level popularity also positively predicted their submissiveness and negatively predicted their task influence. These results indicate that, in particular for girls, adolescents' group level popularity plays an important role in the behavior of both peers in a cooperative dyadic context. PMID:26232593

  16. Analytical approach for predicting fresh water discharge in an estuary based on tidal water level observations

    H. Cai

    2014-06-01

    Full Text Available As the tidal wave propagates into an estuary, the tidally averaged water level tends to rise in landward direction due to the density difference between saline and fresh water and the asymmetry of the friction. The effect of friction on the residual slope is even more remarkable when accounting for fresh water discharge. In this study, we investigate the influence of river discharge on tidal wave propagation in the Yangtze estuary with specific attention to residual water level slope. This is done by using a one-dimensional analytical model for tidal hydrodynamics accounting for the residual water level. We demonstrate the importance of the residual slope on tidal dynamics and use it to improve the prediction of the tidal propagation in estuaries (i.e., tidal damping, velocity amplitude, wave celerity and phase lag, especially when the influence of river discharge is significant. Finally, we develop a new inverse analytical approach for estimating fresh water discharge on the basis of tidal water level observations along the estuary, which can be used as a tool to obtain information on the river discharge that is otherwise difficult to measure in the tidal region.

  17. A statistical method to get surface level air-temperature from satellite observations of precipitable water

    Pankajakshan, T.; Shikauchi, A.; Sugimori, Y.; Kubota, M.

    humidity within the first 50 meters of the air-sea boundary layer (Friehe and Schmitt, 1976; Liu et al., 1979). Sea surface temperature derived from NOAA-AVHRR infrared channels, using MCSST/CPSST algorithms, has an attainable accuracy of ±0.5°C (McClain et... al., 1985; Walton, 1988; Sakaida and Kawamura, 1992). The operational U.S. DMSP-SSMI provide the surface level wind speed and integrated column water vapor (precipitable water) within an accuracy comparable to in situ observations (Wentz et al., 1986...

  18. Activity Analyses for Solar-Type Stars Observed With Kepler. I. Proxies of Magnetic Activity

    He, Han; Yun, Duo

    2016-01-01

    Light curves of solar-type stars often show gradual fluctuations due to rotational modulation by magnetic features (starspots and faculae) on stellar surfaces. Two quantitative measures of modulated light curves are employed as the proxies of magnetic activity for solar-type stars observed with Kepler telescope. The first is named autocorrelation index $i_{AC}$, which describes the degree of periodicity of the light curve, the second is the effective fluctuation range of the light curve $R_{eff}$, which reflects the depth of rotational modulation. The two measures are complementary and depict different aspects of magnetic activities on solar-type stars. By using the two proxies $i_{AC}$ and $R_{eff}$, we analyzed activity properties of two carefully selected solar-type stars observed with Kepler (Kepler ID: 9766237 and 10864581), which have distinct rotational periods (14.7 vs. 6.0 days). We also applied the two measures to the Sun for a comparative study. The result shows that both the measures can reveal cy...

  19. Mapping Air Pollution Concentrations and Sources in China from Ground-Level Observations

    Rohde, R. A.; Muller, R. A.

    2014-12-01

    China has recently established an extensive air quality monitoring system with over 1500 sites providing hourly data on airborne particulate matter (PM2.5 / PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), ozone (O3), and carbon monoxide (CO). Based on Kriging interpolation of these surface data, we derive a detailed map of air pollution across the eastern half of China. In northern and central China, the pollution is widespread; contrary to popular belief, pollution is not simply localized to major cities such as Beijing, Shanghai, or Chongqing, or in geologic basins. Pollution levels are lower in southern China, in part due to frequent rains. By incorporating wind measurements and estimating pollution transport, we also infer source distributions for key pollutants. Sources are widespread, but many of the largest sources are often situated in or near major population centers. A northeast corridor extending from near Shanghai to north of Beijing includes many of the most significant pollution sources in China. Roughly 5% of the study region accounts for 25% of observed particulate matter emissions. During the analysis period, roughly half of the population of China was subjected to a long-term average pollution level in the unhealthy range, according to standards used by the US Environmental Protection Agency. In addition, nearly all of China's population (>90%) was exposed to unhealthy levels of air pollution at least some of the time. Based on health impact estimates from the Huai River Study, we estimate that the observed levels of particulate matter pollution contribute to about 1.4 million deaths every year in China, about 3500 per day, in agreement with prior estimates. Identification of sources from pollution data was facilitated by the reporting of hourly measurements, and we encourage other nations around the world to follow China's example and provide such time-resolved data.

  20. Assimilation of Smos Observations to Generate a Prototype SMAP Level 4 Surface and Root-Zone Soil Moisture Product

    Reichle, Rolf H.; De Lannoy, Gabrielle J. M.; Crow, Wade T.; Koster, Randal D.; Kimball, John

    2012-01-01

    The Soil Moisture Active and Passive (SMAP; [1]) mission is being implemented by NASA for launch in October 2014. The primary science objectives of SMAP are to enhance understanding of land surface controls on the water, energy and carbon cycles, and to determine their linkages. Moreover, the high-resolution soil moisture mapping provided by SMAP has practical applications in weather and seasonal climate prediction, agriculture, human health, drought and flood decision support. The Soil Moisture and Ocean Salinity (SMOS; [2]) mission was launched by ESA in November 2009 and has since been observing L-band (1.4 GHz) upwelling passive microwaves. In this paper we describe our use of SMOS brightness temperature observations to generate a prototype of the planned SMAP Level 4 Surface and Root-zone Soil Moisture (L4_SM) product [5].

  1. Very Large Array (VLA) observations of solar active regions

    Very Large Array (VLA) synthesis maps of the total intensity and the circular polarization of three active regions at 6 cm wavelength are presented. The radiation from each active region is dominated by a few intense cores with angular sizes of approximately 0.5', brightness temperatures of approximately 106 K, and degrees of circular polarization of 30 to 90%. Some of the core sources within a given active region exhibit opposite senses of circular polarization, suggesting the feet of magnetic dipoles, and the high brightness temperatures suggest that these magnetic structures belong to the low solar corona. Comparisons between the VLA maps of circular polarization and Zeeman effect magnetograms of the lower lying photosphere are presented. There is an excellent correlation between the magnetic structures inferred by the two methods, indicating that synthesis maps of circular polarization at 6 cm can be used to delineate magnetic structures in the low solar corona. (Auth.)

  2. Closure Plan for Active Low Level Burial Grounds

    SKELLY, W.A.

    2000-11-16

    This plan has been prepared in response to direction from the U.S. Department of Energy. The purpose of the plan is to define approaches that will be implemented to ensure protection of the public and the environment when active Low-Level Burial Grounds (LLBGs) at the Hanford Site are closed. Performance assessments for active burial grounds in the 200 East and West 200 Areas provide current estimates of potential environmental contamination and doses to the ''maximum exposed individual'' from burial ground operation and closure and compare dose estimates to performance objective dose limits for the facilities. This is an Operational Closure Plan. The intent of the guidance in DOE Order 435.1 is that this plan will be a living document, like the facility performance assessments, and will be revised periodically through the operational life of the LLBGs to reflect updated information on waste inventory. management practices, facility transition planning, schedule dates, assessments of post-closure performance, and environmental consequences. Out year dates identified in this plan are tentative. A Final Closure Plan will be prepared in the future when the timing and extent of closure-related activities for LLBGs can be established with greater certainty. After current operations at the LLBGs are concluded, this plan proposes transitioning of these facilities to the Environmental Restoration Program. This action will enable the Environmental Restoration Program to design and implement consistent and coordinated final remedial actions for active and inactive LLBGs. Active and inactive burial grounds in the 200 West and 200 East Areas are commingled. This plan describes approaches that will be implemented during Interim Closure, Final Closure, and Institutional Control Periods to prepare LLBGs for surface barriers, and the construction of barriers, as well as the scope of inspection, monitoring and maintenance practices that will be performed during

  3. Sources of Continuity and Change in Activity Level in Early Childhood

    Saudino, Kimberly J.

    2011-01-01

    Actigraphs and parent and observer ratings were used to explore genetic influences on continuity and change in activity level (AL) in early childhood. Over 300 pairs of twins wore actigraphs for a 48-hour period in the home and laboratory at ages 2 and 3. AL was genetically influenced at both ages with little evidence of differential heritability across age. For all measures, genetic influences contributed to phenotypic continuity. With the exception of the actigraph measure of AL in the home...

  4. Geographical and Temporal Differences in NOAA Observed Ground-Level Ozone in the Arctic

    McClure-Begley, Audra; Petropavlovskikh, Irina; Andrews, Betsy; Hageman, Derek; Oltmans, Samuel; Uttal, Taneil

    2016-04-01

    The Arctic region is rapidly gaining interest and support for scientific studies to help understand and characterize the processes, sources, and chemical composition of the Arctic environment. In order to understand the Arctic climate system and the changes that are occurring, it is imperative to know the behavior and impact of atmospheric constituents. Surface level ozone in the Arctic is variable in both time and space and plays an essential role on the oxidation capacity of the atmosphere. NOAA Global Monitoring Division (NOAA/GMD) maintains continuous measurements and long-term records of ground-level ozone from Barrow, Alaska (since 1973) and Summit, Greenland (since 2000). Measurements taken by Thermo-Scientific ozone monitors are collected and examined with the NOAA/GMD Aerosol LiveCPD acquisition and software. These quality controlled data are used to develop seasonal climatologies, understand diurnal variation, and analyze differences in stations specifics by addressing spatial variability in the Arctic. Once typical ozone behavior is characterized, anomalies in the record are defined and investigated. Increased ozone events associated with transported pollution and photochemical production of ozone, and ozone depletion episodes related to sea-ice halogen release and chemical destruction of ozone are the primary processes which lead to deviations from typical ground-level ozone conditions. The measurements taken from Barrow and Summit are a critical portion of the IASOA network of observations of ground-level ozone and are investigated to ensure proper data management and quality control, as well as provide the fundamental understanding of ground-level ozone behavior in the Arctic.

  5. Digestive enzyme activity and mRNA level of trypsin in embryonic redclaw crayfish, Cherax quadricarnatus

    LUO Wen; ZHAO Yunlong; ZHOU Zhongliang; AN Chuanguang; MA Qiang

    2008-01-01

    The digestive enzyme activity and mRNA level of trypsin during the embryonic development of Cherax quadricarinatus were analyzed using biochemical and Fluorogenic Quantitative PCR (FQ-PCR) methods.The results show that the activities of trypsin and chymotrypsin had two different change patterns.Trypsin specific activity increased rapidly in the early stages of development and still remained high in preparation for the hatch stage.However,chymotrypsin activity peaked in stage 4 of embryonic development and decreased significantly in the last stage.The mRNA level of trypsin was elevated in all stages and two peak values were observed in stages 2 and 5 respectively.The results indicate that trypsin is very important for the utilization of the yolk during embryonic development and for the assimilation of dietary protein for larvae.The gene of trypsin is probably regulated at transcriptional level.The mRNA levels of trypsin can reflect not only trypsin activity,but also the regulatory mechanism for expression of trypsin gene to a certain degree.

  6. Direct observation of atomic-level nucleation and growth processes from an ultrathin metallic glass films

    Huang, K. Q.; Cao, C. R.; Sun, Y. T.; Li, J.; Bai, H. Y.; Zheng, D. N., E-mail: l.gu@iphy.ac.cn, E-mail: dzheng@iphy.ac.cn, E-mail: whw@iphy.ac.cn; Wang, W. H., E-mail: l.gu@iphy.ac.cn, E-mail: dzheng@iphy.ac.cn, E-mail: whw@iphy.ac.cn [Institute of Physics, Chinese Academy of Sciences, Beijing 100190 (China); Gu, L., E-mail: l.gu@iphy.ac.cn, E-mail: dzheng@iphy.ac.cn, E-mail: whw@iphy.ac.cn [Institute of Physics, Chinese Academy of Sciences, Beijing 100190 (China); Collaborative Innovation Center of Quantum Matter, Beijing 100190 (China)

    2016-01-07

    Till date, there have been no direct atomic-level experimental observations of the earliest stages of the nucleation and growth processes of nanocrystals formed by thermally induced crystallization in ultrathin metallic glasses (MGs). Here, we present a study of the crystallization process in atomically thin and highly stable MG films using double spherical aberration-corrected scanning transmission electron microscopy (Cs-TEM). Taking advantage of the stability of MG films with a slow crystallization process and the atomic-level high resolution of Cs-TEM, we observe the formation of the nucleus precursor of nanocrystals formed by atom aggregation followed by concomitant coalescence and stepwise evolution of the shape of the nanocrystals with a monodispersed and separated bimodal size distribution. Molecular dynamics simulation of the atomic motion in the glass film on a rigid amorphous substrate confirms the stepwise evolution processes of atom aggregation, cluster formation, cluster movement on the substrate, and cluster coalescence into larger crystalline particles. Our results might provide a better fundamental understanding of the nucleation and growth processes of nanocrystals in thin MG films.

  7. Direct observation of atomic-level nucleation and growth processes from an ultrathin metallic glass films

    Till date, there have been no direct atomic-level experimental observations of the earliest stages of the nucleation and growth processes of nanocrystals formed by thermally induced crystallization in ultrathin metallic glasses (MGs). Here, we present a study of the crystallization process in atomically thin and highly stable MG films using double spherical aberration-corrected scanning transmission electron microscopy (Cs-TEM). Taking advantage of the stability of MG films with a slow crystallization process and the atomic-level high resolution of Cs-TEM, we observe the formation of the nucleus precursor of nanocrystals formed by atom aggregation followed by concomitant coalescence and stepwise evolution of the shape of the nanocrystals with a monodispersed and separated bimodal size distribution. Molecular dynamics simulation of the atomic motion in the glass film on a rigid amorphous substrate confirms the stepwise evolution processes of atom aggregation, cluster formation, cluster movement on the substrate, and cluster coalescence into larger crystalline particles. Our results might provide a better fundamental understanding of the nucleation and growth processes of nanocrystals in thin MG films

  8. Scheduling satellite imagery acquisition for sequential assimilation of water level observation into flood modelling

    García-Pintado, Javier; Neal, Jeff C.; Mason, David C.; Dance, Sarah L.; Bates, Paul D.

    2013-04-01

    Satellite-based imagery has proved useful for obtaining information on water levels in flood events. Microwave frequencies are generally more useful for flood detection than visible-band sensors because of its all-weather day-night capability. Specifically, the future SWOT mission, with Ka-band interferometry, will be able to provide direct Water Level Observations (WLOs), and current and future Synthetic Aperture Radar (SAR) sensors can provide information of flood extent, which, when intersected with a Digital Elevation Model (DEM) of the floodplain, provides indirect WLOs. By either means, satellite-based WLOs can be assimilated into a hydrodynamic model to decrease forecast uncertainty and further to estimate river discharge into the flooded domain. Operational scenarios can even make a combined use of imagery from different uncoordinated missions to sequentially estimate river discharge. Thus, with an increasing number of operational satellites with WLO capability, information on the relationship between satellite first visit, revisit times, and forecast performance is required to optimise the operational scheduling of satellite imagery. By using an Ensemble Transform Kalman Filter (ETKF) and a synthetic analysis with the 2D hydrodynamic model LISFLOOD-FP based on a real flooding case affecting an urban area (summer 2007, Tewkesbury, Southwest UK), we evaluate the sensitivity of the forecast performance to visit parameters. As an example, we use different scenarios of revisit times and observational errors expected from the current COSMO-Skymed (CSK) constellation, with X-band SAR. We emulate a generic hydrologic-hydrodynamic modelling cascade by imposing a bias and spatiotemporal correlations to the inflow error ensemble into the hydrodynamic domain. First, in agreement with previous research, estimation and correction for this bias leads to a clear improvement in keeping the forecast on track. Second, imagery obtained early in the flood is shown to have a

  9. A Very Active Sprite-Producing Storm Observed Over Argentina

    Thomas, J.N.; Taylor, Michael J.; Pautet, D.; Bailey, M.; Solorzano, N. N.; R. H. Holzworth; McCarthy, M.P.; Kokorowski, M.; Sao Sabbas, F.; Pinto Jr., O.; Cummer, S. A.; Jaugey, N.; Li, J.; Schuch, N. J.

    2007-01-01

    During the night of 22–23 February 2006, more than 400 middle- atmospheric optical discharges were observed above one large thunderstorm system over northeastern Argentina. These transient luminous events (TLEs) were imaged during the Southern Brazil Sprite Campaign, the first campaign to focus on TLEs over southern Brazil, northeastern Argentina, and Uruguay. All of the TLEs were imaged from the Brazilian Southern Space Observatory (SSO) near Santa Maria, which is nearly in the center of the...

  10. Observational evidence of temperature trends at two levels in the surface layer

    Lin, X.; Pielke, R. A., Sr.; Mahmood, R.; Fiebrich, C. A.; Aiken, R.

    2015-09-01

    Long-term surface air temperatures at 1.5 m screen level over land are used in calculating a global average surface temperature trend. This global trend is used by the IPCC and others to monitor, assess, and describe global warming or warming hiatus. Current knowledge of near-surface temperature trends with respect to height, however, is limited and inadequately understood because surface temperature observations at different heights in the surface layer in the world are rare especially from a high-quality and long-term climate monitoring network. Here we use high-quality two-height Oklahoma Mesonet observations, synchronized in time, fixed in height, and situated in relatively flat terrain, to assess temperature trends and differentiating temperature trends with respect to heights (i.e., near-surface lapse rate trend) over the period 1997 to 2013. We show that the near-surface lapse rate has significantly decreased with a trend of -0.18 ± 0.03 °C (10 m)-1 decade-1 indicating that the 9 m height temperatures increased faster than temperatures at the 1.5 m screen level and conditions at the 1.5 m height cooled faster than at the 9 m height. However, neither of the two individual height temperature trends by themselves were statistically significant. The magnitude of lapse rate trend is greatest under lighter winds at night. Nighttime lapse rate trends were significantly more negative than daytime lapse rate trends and the average lapse rate trend was three times more negative under calm conditions than under windy conditions. Our results provide the first observational evidence of near-surface temperature changes with respect to height that could enhance the assessment of climate model predictions.

  11. Long-term Behaviour Of Venus Winds At Cloud Level From Virtis/vex Observations

    Hueso, Ricardo; Peralta, J.; Sánchez-Lavega, A.; Pérez-Hoyos, S.; Piccioni, G.; Drossart, P.

    2009-09-01

    The Venus Express (VEX) mission has been in orbit to Venus for more than three years now. The VIRTIS instrument onboard VEX observes Venus in two channels (visible and infrared) obtaining spectra and multi-wavelength images of the planet. Images in the ultraviolet range are used to study the upper cloud at 66 km while images in the infrared (1.74 μm) map the opacity of the lower cloud deck at 48 km. Here we present an analysis of the overall dynamics of Venus’ atmosphere at both levels using observations that cover a large fraction of the VIRTIS dataset. We will present our latest results concerning the zonal winds, the overall stability in the lower cloud deck motions and the variability in the upper cloud. Meridional winds are also observed in the upper and lower cloud in the UV and IR images obtained with VIRTIS. While the upper clouds present a net meridional motion consistent with the upper branch of a Hadley cell the lower cloud present more irregular, variable and less intense motions in the meridional direction. Acknowledgements This work has been funded by Spanish MEC AYA2006-07735 with FEDER support and Grupos Gobierno Vasco IT-464-07. RH acknowledges a "Ramón y Cajal” contract from MEC.

  12. Observations of cold magnetospheric ions at geosynchronous orbit during times of high activity

    Flowing, cold magnetospheric ions have been observed in conjunction with geosynchronous orbit magnetopause crossings since the earliest ATS and OGO missions. The authors have reported on the occurrence and convection of low-energy (10-100 eV) ions seen by multiple satellites in association with geosynchronous orbit magnetopause and low-latitude boundary layer (LLBL) encounters. More generally, Los Alamos 3-D plasma instruments observe these ions following storm sudden commencements (SSCs), when activity levels are high. The ions appear to be convecting radially outward and usually westward at speeds of a few to several tens of kilometers per second. Often the energy spectra reveal peaks at energies appropriate for cold convecting H+, He+ and O+. The occurrence frequency distribution of these dense cold ions is peaked near 1400 LT, with an overall range from 1000 to beyond 1800 LT. This local time distribution is greatly skewed from the overall plasmaspheric distribution, which peaks closer to 1800 LT. Multisatellite observations show that the ions are seen first at late afternoon local times and then at progressively earlier and earlier local times (though usually no earlier than 1000 LT). This apparent evolution in local time suggests that the late-afternoon plasmaspheric plasma moves out and dawnward during times of increased magnetospheric activity. The three-satellite observations also allow the authors to track cold plasma convection at multiple points in the magnetosphere, and potentially provide a glimpse of the large-scale convection pattern

  13. Kepler Observations of Rapid Optical Variability in Active Galactic Nuclei

    Mushotzky, R. F.; Edelson, R.; Baumgartner, W. H.; Gandhi, P.

    2012-01-01

    Over three quarters in 2010 - 2011, Kepler monitored optical emission from four active galactic nuclei (AGN) with approx 30 min sampling, > 90% duty cycle and approx AGN optical fluctuation power spectral density functions (PSDs) over a wide range in temporal frequency. Fits to these PSDs yielded power law slopes of -2.6 to -3.3, much steeper than typically seen in the X-rays. We find evidence that individual AGN exhibit intrinsically different PSD slopes. The steep PSD fits are a challenge to recent AGN variability models but seem consistent with first order MRI theoretical calculations of accretion disk fluctuations.

  14. Observation of Paramagnetic Raman Optical Activity of Nitrogen Dioxide

    Šebestík, Jaroslav; Bouř, Petr

    2014-01-01

    Roč. 53, č. 35 (2014), s. 9236-9239. ISSN 1433-7851 R&D Projects: GA ČR GAP208/11/0105; GA ČR(CZ) GA14-00431S; GA MŠk(CZ) LH11033 Grant ostatní: GA AV ČR(CZ) M200550902 Institutional support: RVO:61388963 Keywords : angular momentum theory * nitrogen dioxide * paramagnetic gases * Raman optical activity * spectral simulations Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 11.261, year: 2014

  15. Flarelike brightenings of active region loops observed with SUMER

    Wang, T J; Solanki, S K; Curdt, W

    2015-01-01

    Coronal loops on the east limb of the Sun were observed by SUMER on SOHO for several days. Small flare-like brightenings are detected very frequently in the hot flare line Fe~{\\small XIX}. We find that the relatively intense events are in good coincidence with the transient brightenings seen by Yohkoh/SXT. A statistical analysis shows that these brightenings have durations of 5-84 min and extensions along the slit of 2-67 Mm. The integrated energy observed in Fe~{\\small XIX} for each event is in the range of $3\\times10^{18}-5\\times10^{23}$ ergs, and the estimated thermal energy ranges from $10^{26}-10^{29}$ ergs. Application of the statistical method proposed by Parnell \\& Jupp (2000) yields a value of 1.5 to 1.8 for the index of a power law relation between the frequency of the events and the radiated energy in Fe~{\\small XIX}, and a value of 1.7 to 1.8 for the index of the frequency distribution of the thermal energy in the energy range $>10^{27}$ ergs. We examine the possibility that these small bright...

  16. How much locomotive activity is needed for an active physical activity level: analysis of total step counts

    Ohkawara Kazunori

    2011-11-01

    Full Text Available Abstract Background Although physical activity recommendations for public health have focused on locomotive activity such as walking and running, it is uncertain how much these activities contribute to overall physical activity level (PAL. The purpose of the present study was to determine the contribution of locomotive activity to PAL using total step counts measured in a calorimeter study. Methods PAL, calculated as total energy expenditure divided by basal metabolic rate, was evaluated in 11 adult men using three different conditions for 24-hour human calorimeter measurements: a low-activity day (L-day targeted at a low active level of PAL (1.45, and a high-frequency moderate activity day (M-day or a high-frequency vigorous activity day (V-day targeted at an active level of PAL (1.75. These subjects were permitted only light activities except prescribed activities. In a separate group of 41 adults, free-living PAL was evaluated using doubly-labeled water (DLW. In both experiments, step counts per day were also measured using an accelerometer. Results In the human calorimeter study, PAL and step counts were 1.42 ± 0.10 and 8,973 ± 543 steps/d (L-day, 1.82 ± 0.14 and 29,588 ± 1,126 steps/d (M-day, and 1.74 ± 0.15 and 23,755 ± 1,038 steps/d (V-day, respectively. In the DLW study, PAL and step counts were 1.73 ± 0.15 and 10,022 ± 2,605 steps/d, and there was no significant relationship between PAL and daily step counts. Conclusions These results indicate that an enormous number of steps are needed for an active level of PAL if individuals extend physical activity-induced energy expenditure by only locomotive activity. Therefore, non-locomotive activity such as household activity should also play a significant role in increasing PAL under free-living conditions.

  17. Two Decades of Global and Regional Sea Level Observations from the ESA Climate Change Initiative Sea Level Project

    Legeais, JeanFrancois; Larnicol, Gilles; Cazenave, Anny; Ablain, Michael; Benveniste, Jérôme; Lucas, BrunoManuel; Timms, Gary; Johannessen, Johnny; Knudsen, Per; Cipollini, Paolo; Roca, Monica; Rudenko, Sergei; Fernandes, Joana; Balmaseda, Magdalena; Quartly, Graham; Fenoglio-Marc, Luciana; Scharfennberg, Martin; Meyssignac, Benoit; Guinle, Thierry; Andersen, Ole

    2015-04-01

    Sea level is a very sensitive index of climate change and variability. Sea level integrates the ocean warming, mountain glaciers and ice sheet melting. Understanding the sea level variability and changes implies an accurate monitoring of the sea level variable at climate scales, in addition to understanding the ocean variability and the exchanges between ocean, land, cryosphere, and atmosphere. That is why Sea Level is one of the Essential Climate Variables (ECV) selected in the frame of the ESA Climate Change Initiative (CCI) program. It aims at providing long-term monitoring of the sea level ECV with regular updates, as required for climate studies. After a first phase (2011-2013), the program has started in 2014 a second phase of 3 years. The objectives of this second phase are to involve the climate research community, to refine their needs and collect their feedbacks on product quality, to develop, test and select the best algorithms and standards to generate an updated climate time series and to produce and validate the Sea Level ECV product. This will better answer the climate user needs by improving the quality of the Sea Level products and maintain a sustain service for an up-to-date production. To this extent, the ECV time series has been extended and it now covers the period 1993-2013. We will firstly present the main achievements of the ESA CCI Sea Level Project. On the one hand, the major steps required to produce the 21 years climate time series are briefly described: collect and refine the user requirements, development of adapted algorithms for climate applications and specification of the production system. On the other hand, the product characteristics are described as well as the results from product validation, performed by several groups of the ocean and climate modeling community. At last, the work plan and key challenges of the second phase of the project are described.

  18. Low-Level Cloud Variability over the Equatorial Cold Tongue in Observations and Models

    Mansbach, David K.; Norris, Joel R.

    2007-01-01

    A fourth paper now in press is, Low-level cloud variability over the equatorial cold tongue in observations and models, by D. K. Mansbach and J. R. Norris (2007, J. Climate). This study examined cloud and meteorological observations from satellite, surface, and reanalysis datasets and fount that monthly anomalies in low-level cloud amount and near-surface temperature advection are strongly negatively correlated on the southern side of the equatorial Pacific cold tongue. This inverse correlation occurs independently of relationships between cloud amount and sea surface temperature (SST) or lower tropospheric static stability (LTS) and the combination of advection plus SST or LTS explains significantly more interannual cloud variability in a multilinear regression than does SST or LTS alone. Warm anomalous advection occurs when the equatorial cold tongue is well defined and the southeastern Pacific trade winds bring relatively warm air over colder water. Ship meteorological reports and soundings show that the atmospheric surface layer becomes stratified under these conditions, thus inhibiting the upward mixing of moisture needed to sustain cloudiness against subsidence and entrainment drying. Cold anomalous advection primarily occurs when the equatorial cold tongue is weak or absent and the air-sea temperature difference is substantially negative. These conditions favor a more convective atmospheric boundary layer, greater cloud amount, and less frequent occurrence of clear sky. Examination of output from global climate models developed by the Geophysical Fluid Dynamics Laboratory (GFDL) and the National Center for Atmospheric Research (NCAR) indicates that both models generally fail to simulate the cloud-advection relationships observed on the northern and southern sides of the equatorial cold tongue. Although the GFDL atmosphere model does reproduce the expected signs of cloud-advection correlations when forced with prescribed historical SST variations, it does not

  19. Environmental variation of arsenic levels in human blood determined by neutron activation analysis

    Heydorn, Kaj

    1970-01-01

    Arsenic levels in blood plasma and red cells from patients with Blackfoot disease, a peripheral arteriosclerosis endemic to a small area in Taiwan, were studied in relation to healthy individuals from the same and other parts of Taiwan and compared with arsenic levels in a control group from Denm...... in Denmark, which geochemically belongs to a soil zone with less arsenic than Taiwan.......Arsenic levels in blood plasma and red cells from patients with Blackfoot disease, a peripheral arteriosclerosis endemic to a small area in Taiwan, were studied in relation to healthy individuals from the same and other parts of Taiwan and compared with arsenic levels in a control group from...... Denmark. Arsenic was determined by neutron activation analysis with radiochemical separation and re-irradiation yield determination. The precision and accuracy of the results have been carefully evaluated in order to permit quantitative tests for the significance of the observed differences. The results...

  20. Neutron activation analysis of neonate and maternal hair sampled in areas with different levels of pollution

    Instrumental neutron activation analysis was performed on human head hair of newborns and mothers sampled in two areas with different levels of environmental exposure. The group of neonates from the exposed area (polluted by thermal power plants burning brown coal and by chemical industry) exhibited higher levels of several trace elements in hair, e.g. Se, Zn, Hg and Sb in comparison with the control group. Moreover, the mean concentrations of Se, Hg, Zn and Br in neonate hair were found to be higher than in mothers' hair. Although the study revealed statistically significant differences in the composition of neonate hair samples in areas with different levels of environmental exposure, the differences are relatively small. Only a thorough long-term study both with environmental and medical observations can prove a direct connection of the elevated levels of some trace elements in neonate hair with the higher incidence of mental diseaes of children living in the exposed area. (author)

  1. Two Decades of Global and Regional Sea Level Observation from the ESA Climate Change Initiative Sea Level Project

    Larnicol, Gilles; Cazenave, Anny; Ablain, Michael; Legeais, JeanFrancois; Faugere, Yannice; Benveniste, Jerome; Lucas, Bruno; Dinardo, Salvatore; Johannessen, Johnny; Stammer, Detlef; Timms, Gary; Knudsen, Per; Cipollini, Paolo; Roca, Monica; Rudenko, Sergei; Fernandes, Joana; Balmaseda, Magdalena; Guinle, Thierry

    2014-05-01

    Sea level is a very sensitive index of climate change and variability. Sea level integrates the ocean warming, mountain glaciers and ice sheet melting. Understanding the sea level variability and changes implies an accurate monitoring of the sea level variable at climate scales, in addition to understanding the ocean variability and the exchanges between ocean, land, cryosphere, and atmosphere. That is why Sea Level is one of the Essential Climate Variables (ECV) selected in the frame of the ESA Climate Change Initiative (CCI) program. This program aims at providing long-term satellite-based products for climate (ECV products), that should be used by the climate research community. This program has just completed its first phase (Oct. 2010 to Dec. 2013) and will start in February 2014 the second phase of 3 years. The objective of the second phase are similar: to involve the climate research community to refine their needs and collect their feedbacks on product quality, to develop, test and select the best algorithms and standards to generate an updated climate time series and to produce and validate the Sea Level ECV product. This will better answer the climate user needs by improving the quality of the Sea Level products and maintain a sustain service for an up-to-date production. We will firstly present the main achievements of the ESA CCI Sea Level Project. On the one hand, the major steps required to produce the 18 years climate time series (delivered in Sept. 2012) are briefly described: collect and refine the user requirements, development of adapted algorithms for climate applications and specification of the production system. On the other hand, the product characteristics are described as well as the results from product validation, performed by several groups of the ocean and climate modeling community. At last, the work plan and key challenges of the second phase of the project are described.

  2. Fire testing of fully active medium-level waste forms

    The effect of heat on packaged intermediate level waste (ILW) has been studied. This was done in order to be able to predict the behaviour of the ILW under accident conditions involving fire during transport or at the repository. In the study, experimental data were obtained and used in the development and validation of theoretical models to describe aspects of the behaviour of the waste form when subjected to heat. The prime objective was to be able to predict the amounts of radioactive materials released from a given incident. Four ILW streams were selected for experimental study. These four were chosen as the minimum that could be studied to provide a set of data that could be used in the prediction of the behaviour of the majority of ILW produced in the UK. Heating experiments were carried out on a small scale using packaged ILW samples made from active wastes or inactive simulants. Data were obtained on temperatures in the waste form, production of volatile materials, carry-forward of solid particulate materials and carry-forward of radionuclides. The results were used, together with data from full-scale experiments with inactive simulant ILW carried out at Winfrith, to develop and validate a theoretical model. This model calculates the temperature profiles within a package of immobilized ILW as a function of the applied heating conditions. The temperature of the waste form is used to predict the release of radioactive materials from the package. 4 refs., 65 figs., 13 tabs

  3. Paired galaxies with different activity levels and their supernovae

    Nazaryan, T A; Hakobyan, A A; Adibekyan, V Zh; Kunth, D; Mamon, G A; Turatto, M; Aramyan, L S

    2013-01-01

    We investigate the influence of close neighbor galaxies on the properties of supernovae (SNe) and their host galaxies using 56 SNe located in pairs of galaxies with different levels of star formation (SF) and nuclear activity. The statistical study of SN hosts shows that there is no significant difference between morphologies of hosts in our sample and the larger general sample of SN hosts in the Sloan Digital Sky Survey (SDSS) Data Release 8 (DR8). The mean distance of type II SNe from nuclei of hosts is greater by about a factor of 2 than that of type Ibc SNe. The distributions and mean distances of SNe are consistent with previous results compiled with the larger sample. For the first time it is shown that SNe Ibc are located in pairs with significantly smaller difference of radial velocities between components than pairs containing SNe Ia and II. We consider this as a result of higher star formation rate (SFR) of these closer systems of galaxies. SN types are not correlated with the luminosity ratio of ho...

  4. KEPLER OBSERVATIONS OF RAPID OPTICAL VARIABILITY IN ACTIVE GALACTIC NUCLEI

    Over three quarters in 2010-2011, Kepler monitored optical emission from four active galactic nuclei (AGNs) with ∼30 minute sampling, >90% duty cycle, and ∼<0.1% repeatability. These data determined the AGN optical fluctuation power spectral density (PSD) functions over a wide range in temporal frequency. Fits to these PSDs yielded power-law slopes of –2.6 to –3.3, much steeper than typically seen in the X-rays. We find evidence that individual AGNs exhibit intrinsically different PSD slopes. The steep PSD fits are a challenge to recent AGN variability models but seem consistent with first-order magnetorotational instability theoretical calculations of accretion disk fluctuations.

  5. Observable Lepton Number Violation with Predominantly Dirac Nature of Active Neutrinos

    Borah, Debasish

    2016-01-01

    We study a specific version of $SU(2)_R \\times SU(2)_L \\times U(1)_{B-L}$ models extended by discrete symmetries where the new physics sector responsible for tiny neutrino masses at leading order remains decoupled from the new physics sector that can give rise to observable signatures of lepton number violation such as neutrinoless double beta decay. More specifically, the dominant contribution to light neutrino masses comes from a one-loop Dirac mass. At higher loop level, a tiny Majorana mass also appears which remains suppressed by many order of magnitudes in comparison to the Dirac mass. Such a model where the active neutrinos are predominantly of Dirac type, also predicts observable charged lepton flavour violation like $\\mu \\rightarrow 3e, \\mu \\rightarrow e \\gamma$ and multi-component dark matter.

  6. Ocean impact on decadal Atlantic climate variability revealed by sea-level observations

    McCarthy, Gerard D.; Haigh, Ivan D.; Hirschi, Joël J.-M.; Grist, Jeremy P.; Smeed, David A.

    2015-05-01

    Decadal variability is a notable feature of the Atlantic Ocean and the climate of the regions it influences. Prominently, this is manifested in the Atlantic Multidecadal Oscillation (AMO) in sea surface temperatures. Positive (negative) phases of the AMO coincide with warmer (colder) North Atlantic sea surface temperatures. The AMO is linked with decadal climate fluctuations, such as Indian and Sahel rainfall, European summer precipitation, Atlantic hurricanes and variations in global temperatures. It is widely believed that ocean circulation drives the phase changes of the AMO by controlling ocean heat content. However, there are no direct observations of ocean circulation of sufficient length to support this, leading to questions about whether the AMO is controlled from another source. Here we provide observational evidence of the widely hypothesized link between ocean circulation and the AMO. We take a new approach, using sea level along the east coast of the United States to estimate ocean circulation on decadal timescales. We show that ocean circulation responds to the first mode of Atlantic atmospheric forcing, the North Atlantic Oscillation, through circulation changes between the subtropical and subpolar gyres--the intergyre region. These circulation changes affect the decadal evolution of North Atlantic heat content and, consequently, the phases of the AMO. The Atlantic overturning circulation is declining and the AMO is moving to a negative phase. This may offer a brief respite from the persistent rise of global temperatures, but in the coupled system we describe, there are compensating effects. In this case, the negative AMO is associated with a continued acceleration of sea-level rise along the northeast coast of the United States.

  7. Synchronous behaviour of cetaceans observed with active acoustics

    Godø, Olav Rune; Sivle, Lise Doksæter; Patel, Ruben; Torkelsen, Terje

    2013-12-01

    Scientific split-beam echosounders are sensitive instruments for observing biomass densities and individual behaviour. Earlier studies have demonstrated that these instruments can be used to study diving behaviour of cetaceans. In this paper, we go into more detail about the recorded signal to see if and how acoustic split-beam data can be used to extract information about synchronous behaviour and other species related characteristics. Data of several cetacean individuals were collected by a moored echosounder pinging upwards from about 900 m in the Charlie Gibbs Fracture Zone. In this paper, we discuss methodological issues associated with using split-beam tracking of large marine animals. Further we demonstrate that target tracking of cetaceans can be used to study solo dives as well as behavioural synchrony. We also show that paired signals can easily be interpreted as false synchrony due to the size of the animals. In such cases a rough estimate of the diameter, and hence size, of the animals can be estimated. We emphasise on four examples that clarify methodological challenges including synchronous swimmers as well as large single cetaceans that might be interpreted as two synchronous swimmers. The applied technology requires that the animals remain in a narrow acoustic beam for long enough time to extract behavioural information. The technology can be improved by developing automatic tracking of cetaceans with a steerable transducer. This will substantially increase the search volume and enable tracking of cetaceans over longer periods and thus, produce more realistic information about the whale behaviour.

  8. ALMA Observations of the Active Nucleus of NGC 7469

    Izumi, Takuma; Aalto, Susanne; Doi, Akihiro; Espada, Daniel; Fathi, Kambiz; Harada, Nanase; Hatsukade, Bunyo; Hattori, Takashi; Hsieh, Pei-Ying; Ikarashi, Soh; Imanishi, Masatoshi; Iono, Daisuke; Ishizuki, Sumio; Krips, Melanie; Martín, Sergio; Matsushita, Satoki; Meier, David S; Nagai, Hiroshi; Nakai, Naomasa; Nakajima, Taku; Nakanishi, Kouichiro; Nomura, Hideko; Regan, Michael W; Schinnerer, Eva; Sheth, Kartik; Takano, Shuro; Tamura, Yoichi; Terashima, Yuichi; Tosaki, Tomoka; Turner, Jean L; Umehata, Hideki; Wiklind, Tommy

    2015-01-01

    We present ALMA Cycle 1 observations of the central kpc region of the luminous type-1 Seyfert galaxy NGC 7469 with unprecedented high resolution (0.5$"$ $\\times$ 0.4$"$ = 165 pc $\\times$ 132 pc) at submillimeter wavelengths. Utilizing the wide-bandwidth of ALMA, we simultaneously obtained HCN(4-3), HCO$^+$(4-3), CS(7-6), and partially CO(3-2) line maps, as well as the 860 $\\mu$m continuum. The region consists of the central $\\sim$ 1$"$ component and the surrounding starburst ring with a radius of $\\sim$ 1.5$"$-2.5$"$. Several structures connect these components. Except for CO(3-2), these dense gas tracers are significantly concentrated towards the central $\\sim$ 1$"$, suggesting their suitability to probe the nuclear regions of galaxies. Their spatial distribution resembles well those of centimeter and mid-infrared continuum emissions, but it is anti-correlated with the optical one, indicating the existence of dust obscured star formation. The integrated intensity ratios of HCN(4-3)/HCO$^+$(4-3) and HCN(4-3)/...

  9. Upgrading InSAR observations by combination with leveling data to understand small scale deformation processes

    Schenk, A.; Westerhaus, M.

    2012-04-01

    Estimation of surface displacements by InSAR methods has been steadily improved in recent years, mainly by innovative SAR sensors like TerraSAR-X, but also through constantly enhanced processing techniques like persistent scatterer interferometry. Despite its high accuracy plus favorable spatial resolution and coverage, InSAR observation is merely the one dimensional line of sight mapping of the true surface displacement. Thus a combination of InSAR with additional geodetic methods or a precise geodynamic model is inevitable to obtain the full displacement vector. We use leveling data in combination with TerraSAR-X persistent scatterer stacks observed in ascending and descending mode to retrieve the full surface displacement vector. A thin plate spline approximation is modeled for each scalar displacement field to allow for a continuous description of the discrete scattered data set. The thin plate spline model is advantageous as it makes use of general physical properties of deformation processes, like minimum bending energy, without the need for specific deformation geometries and processes. We apply the proposed method to the anthropogenic deformation phenomenon in the city of Staufen (Germany). The city is strongly affected by small scale surface movements with comparably large displacement rates up to 14 mm per month. Well drillings in late 2008 caused mineral conversion of anhydrite layers in depths between 60 and 130 m. The concurrent volume increase causes vertical surface uplift but also horizontal displacements in radial direction. The latter is significant as the inflation source is in comparably shallow depth. With the proposed method we determine the full displacement vector of the Staufen deformation without the use of a geodynamic model. The results of horizontal displacement rates are largely consistent with independent terrestrial observations, whereas some points reveal an overestimation of the westward component due to the glancing intersection

  10. Empathy levels among first year Malaysian medical students: an observational study

    Williams B

    2014-05-01

    Full Text Available Brett Williams,1 Sivalal Sadasivan,2 Amudha Kadirvelu,2 Alexander Olaussen11Department of Community Emergency Health and Paramedic Practice, Melbourne, Australia; 2Jeffrey Cheah School of Medicine and Health Sciences, Sunway Campus, Selangor, MalaysiaBackground: The literature indicates that medical practitioners experience declining empathy levels in clinical practice. This highlights the need to educate medical students about empathy as an attribute early in the academic curriculum. The objective of this study was to evaluate year one students' self-reported empathy levels following a 2-hour empathy workshop at a large medical school in Malaysia.Methods: Changes in empathy scores were examined using a paired repeated-measures t-test in this prospective before and after study.Results: Analyzing the matched data, there was a statistically significant difference and moderate effect size between mean empathy scores before and 5 weeks after the workshop (112.08±10.67 versus 117.93±13.13, P<0.0001, d=0.48 using the Jefferson Scale Physician Empathy (Student Version.Conclusion: The results of this observational study indicate improved mean self-reported empathy scores following an empathy workshop.Keywords: empathy, medical students, Malaysia

  11. Point source influence on observed extreme pollution levels in a monitoring network

    Ensor, Katherine B.; Ray, Bonnie K.; Charlton, Sarah J.

    2014-08-01

    This paper presents a strategy to quantify the influence major point sources in a region have on extreme pollution values observed at each of the monitors in the network. We focus on the number of hours in a day the levels at a monitor exceed a specified health threshold. The number of daily exceedances are modeled using observation-driven negative binomial time series regression models, allowing for a zero-inflation component to characterize the probability of no exceedances in a particular day. The spatial nature of the problem is addressed through the use of a Gaussian plume model for atmospheric dispersion computed at locations of known emissions, creating covariates that impact exceedances. In order to isolate the influence of emitters at individual monitors, we fit separate regression models to the series of counts from each monitor. We apply a final model clustering step to group monitor series that exhibit similar behavior with respect to mean, variability, and common contributors to support policy decision making. The methodology is applied to eight benzene pollution series measured at air quality monitors around the Houston ship channel, a major industrial port.

  12. Millimeter-Wave Measurements of High Level and Low Level Activity Glass Melts

    The primary objectives of the current research is to develop on-line sensors for characterizing molten glass in high-level and low-activity waste glass melters using millimeter-wave (MMW) technology and to use this technology to do novel research of melt dynamics. Existing and planned waste glass melters lack sophisticated diagnostics due to the hot, corrosive, and radioactive melter environments. Without process control diagnostics, the Defense Waste Processing Facility (DWPF) and the Waste Treatment Plant (WTP) under construction at Hanford operate by a feed forward process control scheme that relies on predictive models with large uncertainties. This scheme severely limits production throughput and waste loading. Also operations at DWPF have shown susceptibility to anomalies such as pouring, foaming, and combustion gas build up, which can seriously disrupt operations. Future waste chemistries will be even more challenging. The scientific goals of this project are to develop new reliable on-line monitoring capability for important glass process parameters such as temperature profiles, emissivity, density, viscosity, and other characteristics using the unique advantages of millimeter wave electromagnetic radiation that can be eventually implemented in the operating melters. Once successfully developed and implemented, significant cost savings would be realized in melter operations by increasing production through put, reduced storage volumes (through higher waste loading), and reduced risks (prevention or mitigation of anomalies)

  13. Potential sea-level rise from Antarctic ice-sheet instability constrained by observations

    Ritz, Catherine; Edwards, Tamsin L.; Durand, Gaël; Payne, Antony J.; Peyaud, Vincent; Hindmarsh, Richard C. A.

    2015-12-01

    Large parts of the Antarctic ice sheet lying on bedrock below sea level may be vulnerable to marine-ice-sheet instability (MISI), a self-sustaining retreat of the grounding line triggered by oceanic or atmospheric changes. There is growing evidence that MISI may be underway throughout the Amundsen Sea embayment (ASE), which contains ice equivalent to more than a metre of global sea-level rise. If triggered in other regions, the centennial to millennial contribution could be several metres. Physically plausible projections are challenging: numerical models with sufficient spatial resolution to simulate grounding-line processes have been too computationally expensive to generate large ensembles for uncertainty assessment, and lower-resolution model projections rely on parameterizations that are only loosely constrained by present day changes. Here we project that the Antarctic ice sheet will contribute up to 30 cm sea-level equivalent by 2100 and 72 cm by 2200 (95% quantiles) where the ASE dominates. Our process-based, statistical approach gives skewed and complex probability distributions (single mode, 10 cm, at 2100; two modes, 49 cm and 6 cm, at 2200). The dependence of sliding on basal friction is a key unknown: nonlinear relationships favour higher contributions. Results are conditional on assessments of MISI risk on the basis of projected triggers under the climate scenario A1B (ref. 9), although sensitivity to these is limited by theoretical and topographical constraints on the rate and extent of ice loss. We find that contributions are restricted by a combination of these constraints, calibration with success in simulating observed ASE losses, and low assessed risk in some basins. Our assessment suggests that upper-bound estimates from low-resolution models and physical arguments (up to a metre by 2100 and around one and a half by 2200) are implausible under current understanding of physical mechanisms and potential triggers.

  14. Asian dust storm influence on North American ambient PM levels: observational evidence and controlling factors

    T. L. Zhao

    2008-05-01

    Full Text Available New observational evidence of the trans-Pacific transport of Asian dust and its contribution to the ambient particulate matter (PM levels in North America was revealed, based on the interannual variations between Asian dust storms and the ambient PM levels in western North America from year 2000 to 2006. A high correlation was found between them with an R2 value of 0.83. From analysis of the differences in the correlation between 2005 and 2006, three factors explain the variation of trans-Pacific transport and influences of Asian dust storms on PM levels in western North America. These were identified by modeling results and the re-analysis data. They were 1 Strength of frontal cyclones from Mongolia to north eastern China: The frontal cyclones in East Asia not only bring strong cold air outbreaks, generating dust storms in East Asia, but also lift Asian dust into westerly winds of the free troposphere for trans-Pacific transport; 2 Pattern of transport pathway over the North Pacific: The circulation patterns of westerlies over the North Pacific govern the trans-Pacific transport pattern. Strong zonal airflow of the westerly jet in the free troposphere over the North Pacific favor significant trans-Pacific transport of Asian dust; 3 Variation of precipitation in the North Pacific: The scavenging of Asian dust particles by precipitation is a major process of dust removal on the trans-Pacific transport pathway. Therefore, variation of precipitation in the North Pacific could affect trans-Pacific transport of Asian dust.

  15. Asian dust storm influence on North American ambient PM levels: observational evidence and controlling factors

    T. L. Zhao

    2007-07-01

    Full Text Available New observational evidence of the trans-Pacific transport of Asian dust and its contribution to the ambient particulate matter (PM levels in North America was revealed, based on the interannual variations between Asian dust storms and the ambient PM levels in western North America from year 2000 to 2006. A high correlation was found between them with an R2 value of 0.83. From analysis of the differences in the correlation between 2005 and 2006, three factors explain the variation of trans-Pacific transport and influences of Asian dust storms on PM levels in western North America. These were identified by modeling results and the re-analysis data. They were 1 Strength of frontal cyclones from Mongolia to north eastern China: The frontal cyclones in East Asia not only bring strong cold air outbreaks, generating dust storms in East Asia, but also lift Asian dust into westerly winds of the free troposphere for trans-Pacific transport; 2 Pattern of transport pathway over the North Pacific: The circulation patterns of westerlies over the North Pacific govern the trans-Pacific transport pattern. Strong zonal airflow of the westerly jet in the free troposphere over the North Pacific favor significant trans-Pacific transport of Asian dust; 3 Variation of precipitation in the North Pacific: The scavenging of Asian dust particles by precipitation is a major process of dust removal on the trans-Pacific transport pathway; therefore, variation of precipitation in the North Pacific could affect trans-Pacific transport of Asian dust.

  16. 137Cs airborne levels in the vertical plane from observations taken at high altitude European locations, after the arrival of the Fukushima-labeled air masses

    The Fukushima-labeled air masses reached Europe at different times according to the location. Airborne levels of the released radionuclides also exhibited some discrepancies at local or regional scales, with a corridor of higher activity levels that extended along a NW to SE axis from Scandinavia, across eastern Germany, Poland, the Czech Republic and Belarus. These observations were mostly based on lowlands air samplings, We compare here the variations in the vertical plane by using the maximum airborne 137Cs levels registered at high altitude European locations with what was observed at the closest lowland location. 137Cs levels were systematically lower in altitude. The relation [137Cs]max vs. altitude shows a linear relationship and thus the concentration of activity in the vertical plane was not homogenous even after a long travel time and that Document available in abstract form only. (authors)

  17. Circulating ADAM17 Level Reflects Disease Activity in Proteinase-3 ANCA-Associated Vasculitis.

    Bertram, Anna; Lovric, Svjetlana; Engel, Alissa; Beese, Michaela; Wyss, Kristin; Hertel, Barbara; Park, Joon-Keun; Becker, Jan U; Kegel, Johanna; Haller, Hermann; Haubitz, Marion; Kirsch, Torsten

    2015-11-01

    ANCA-associated vasculitides are characterized by inflammatory destruction of small vessels accompanied by enhanced cleavage of membrane-bound proteins. One of the main proteases responsible for ectodomain shedding is disintegrin and metalloproteinase domain-containing protein 17 (ADAM17). Given its potential role in aggravating vascular dysfunction, we examined the role of ADAM17 in active proteinase-3 (PR3)-positive ANCA-associated vasculitis (AAV). ADAM17 concentration was significantly increased in plasma samples from patients with active PR3-AAV compared with samples from patients in remission or from other controls with renal nonvascular diseases. Comparably, plasma levels of the ADAM17 substrate syndecan-1 were significantly enhanced in active AAV. We also observed that plasma-derived ADAM17 retained its specific proteolytic activity and was partly located on extracellular microparticles. Transcript levels of ADAM17 were increased in blood samples of patients with active AAV, but those of ADAM10 or tissue inhibitor of metalloproteinases 3, which inhibits ADAMs, were not. We also performed a microRNA (miR) screen and identified miR-634 as significantly upregulated in blood samples from patients with active AAV. In vitro, miR-634 mimics induced a proinflammatory phenotype in monocyte-derived macrophages, with enhanced expression and release of ADAM17 and IL-6. These data suggest that ADAM17 has a prominent role in AAV and might account for the vascular complications associated with this disease. PMID:25788529

  18. Family’s presence associated with increased physical activity in patients with acute stroke: an observational study

    V. Prakash

    2016-01-01

    Full Text Available ABSTRACT Background: Inherent differences in organization of stroke care and rehabilitation practices in various settings influence the activity levels of patients in the hospital. The majority of published studies have been carried out in developed countries such as the United States, United Kingdom, Australia, Switzerland and Belgium; however, data from developing countries are scarce. Objective: To measure the amount and nature of physical activity of patients admitted to medical wards of Indian hospitals and to assess the association between family presence and the patient and between the patient’s functional status and their physical activity level. Method: This is an observational behavioral mapping study. A trained physical therapist recorded the patients’ (N=47 physical activity level through direct observation in the ward using a predetermined observation scheme. Results: Participants were found inactive and alone for 19% (inter quartile range [IQR] 12-36% and 15% (IQR 10-19% of the time during the day, respectively. They spent 46% (IQR 31-55% of the time in therapeutic activities and 31% (IQR 22-34% of the time in non-therapeutic activities. The family was present with patients 50% of the time during the day. Family presence with the patient and the patient’s moderate dependence in daily activities are positively associated with their activity levels. Conclusion: Patients with stroke admitted to Indian hospitals spent less time being inactive and alone and more time with family participating in therapeutic activities. The presence of family members with the patients during hospital stay may be a significant resource for encouraging patients to be more active.

  19. Serum Adenosine deaminase activity and C-reactive protein levels in unstable angina

    Rani Surekha

    2003-01-01

    Full Text Available In unstable angina (USA patients, immunological responses contributing to inflammation play a vital role in plaque rupture and thrombosis causing stroke. In the present study an attempt is made to estimate the levels of adenosine deaminase activity, an immunoenzyme marker and C-reactive protein, a marker of inflammation in USA patients. 45 patients presenting USA and 50 age and sex matched healthy controls were included in the study. Serum ADA activity was measured spectrophotometrically at 630nm and serum C-reactive protein was detected using Avitex CRP kit, which is a rapid latex agglutination test. The Mean ADA levels were 41.15 ± 11.04 in patients and 20.71±5.63 in controls and 66.6% of patients and none of the controls were positive to CRP. The present study observed the importance of ADA as a serum marker in addition to CRP for assessing the immune response in USA patients.

  20. Observation of b2 symmetry vibrational levels of the SO2 C ˜ 1B2 state: Vibrational level staggering, Coriolis interactions, and rotation-vibration constants

    Park, G. Barratt; Jiang, Jun; Saladrigas, Catherine A.; Field, Robert W.

    2016-04-01

    The C ˜ 1B2 state of SO2 has a double-minimum potential in the antisymmetric stretch coordinate, such that the minimum energy geometry has nonequivalent SO bond lengths. However, low-lying levels with odd quanta of antisymmetric stretch (b2 vibrational symmetry) have not previously been observed because transitions into these levels from the zero-point level of the X ˜ state are vibronically forbidden. We use IR-UV double resonance to observe the b2 vibrational levels of the C ˜ state below 1600 cm-1 of vibrational excitation. This enables a direct characterization of the vibrational level staggering that results from the double-minimum potential. In addition, it allows us to deperturb the strong c-axis Coriolis interactions between levels of a1 and b2 vibrational symmetry and to determine accurately the vibrational dependence of the rotational constants in the distorted C ˜ electronic state.

  1. Observation of b2 symmetry vibrational levels of the SO2 C̃ (1)B2 state: Vibrational level staggering, Coriolis interactions, and rotation-vibration constants.

    Park, G Barratt; Jiang, Jun; Saladrigas, Catherine A; Field, Robert W

    2016-04-14

    The C̃ (1)B2 state of SO2 has a double-minimum potential in the antisymmetric stretch coordinate, such that the minimum energy geometry has nonequivalent SO bond lengths. However, low-lying levels with odd quanta of antisymmetric stretch (b2 vibrational symmetry) have not previously been observed because transitions into these levels from the zero-point level of the X̃ state are vibronically forbidden. We use IR-UV double resonance to observe the b2 vibrational levels of the C̃ state below 1600 cm(-1) of vibrational excitation. This enables a direct characterization of the vibrational level staggering that results from the double-minimum potential. In addition, it allows us to deperturb the strong c-axis Coriolis interactions between levels of a1 and b2 vibrational symmetry and to determine accurately the vibrational dependence of the rotational constants in the distorted C̃ electronic state. PMID:27083725

  2. Liparid and macrourid fishes of the hadal zone: in situ observations of activity and feeding behaviour.

    Jamieson, A J; Fujii, T; Solan, M; Matsumoto, A K; Bagley, P M; Priede, I G

    2009-03-22

    Using baited camera landers, the first images of living fishes were recorded in the hadal zone (6000-11000 m) in the Pacific Ocean. The widespread abyssal macrourid Coryphaenoides yaquinae was observed at a new depth record of approximately 7000 m in the Japan Trench. Two endemic species of liparid were observed at similar depths: Pseudoliparis amblystomopsis in the Japan Trench and Notoliparis kermadecensis in the Kermadec Trench. From these observations, we have documented swimming and feeding behaviour of these species and derived the first estimates of hadal fish abundance. The liparids intercepted bait within 100-200 min but were observed to preferentially feed on scavenging amphipods. Notoliparis kermadecensis act as top predators in the hadal food web, exhibiting up to nine suction-feeding events per minute. Both species showed distinctive swimming gaits: P. amblystomopsis (mean length 22.5 cm) displayed a mean tail-beat frequency of 0.47 Hz and mean caudal:pectoral frequency ratio of 0.76, whereas N. kermadecensis (mean length 31.5 cm) displayed respective values of 1.04 and 2.08 Hz. Despite living at extreme depths, these endemic liparids exhibit similar activity levels compared with shallow-water liparids. PMID:19129104

  3. GIANT GROUND LEVEL ENHANCEMENT OF RELATIVISTIC SOLAR PROTONS ON 2005 JANUARY 20. I. SPACESHIP EARTH OBSERVATIONS

    Bieber, J. W.; Clem, J.; Evenson, P.; Pyle, R. [Bartol Research Institute and Department of Physics and Astronomy, University of Delaware, Newark, DE 19716 (United States); Saiz, A.; Ruffolo, D., E-mail: jwbieber@bartol.udel.edu, E-mail: clem@bartol.udel.edu, E-mail: evenson@udel.edu, E-mail: pyle@bartol.udel.edu, E-mail: alejandro.sai@mahidol.ac.th, E-mail: david.ruf@mahidol.ac.th [Department of Physics, Faculty of Science Mahidol University, Rama VI Road, Bangkok 10400 (Thailand)

    2013-07-10

    A ground level enhancement (GLE) is a solar event that accelerates ions (mostly protons) to GeV range energies in such great numbers that ground-based detectors, such as neutron monitors, observe their showers in Earth's atmosphere above the Galactic cosmic ray background. GLEs are of practical interest because an enhanced relativistic ion flux poses a hazard to astronauts, air crews, and aircraft electronics, and provides the earliest direct indication of an impending space radiation storm. The giant GLE of 2005 January 20 was the second largest on record (and largest since 1956), with up to 4200% count rate enhancement at sea level. We analyzed data from the Spaceship Earth network, supplemented to comprise 13 polar neutron monitor stations with distinct asymptotic viewing directions and Polar Bare neutron counters at South Pole, to determine the time evolution of the relativistic proton density, energy spectrum, and three-dimensional directional distribution. We identify two energy-dispersive peaks, indicating two solar injections. The relativistic solar protons were initially strongly beamed, with a peak maximum-to-minimum anisotropy ratio over 1000:1. The directional distribution is characterized by an axis of symmetry, determined independently for each minute of data, whose angle from the magnetic field slowly varied from about 60 Degree-Sign to low values and then rose to about 90 Degree-Sign . The extremely high relativistic proton flux from certain directions allowed 10 s tracking of count rates, revealing fluctuations of period {approx}> 2 minutes with up to 50% fractional changes, which we attribute to fluctuations in the axis of symmetry.

  4. Climatic and anthropogenic stress on water levels: basin-scale observations with seismic noise

    Lecocq, Thomas; Pedersen, Helle; Brenguier, Florent; Stammler, Klaus

    2016-04-01

    Monitoring changes in shear wave velocities within the crust have become possible through recently developed techniques based on seismic noise analysis. In the present work we address the challenge of using these techniques for environmental monitoring at upper crustal level. Our work is based on data from the broadband Gräfenberg array (Germany) which was installed in 1976 and for which the continuous data acquired has been preserved until today. Using state of the art pre-processing and cross-correlation techniques (MSNoise), we computed daily cross-correlation functions (CCF) between 4 stations (6 pairs) of the Gräfenberg array over the period 1977-2007. The daily CCFs are then stacked to form an average CCF per month. Instead of doing classic "one versus reference" comparisons, the monthly CCFs are compared pairwise using Moving Window Cross-Spectral analysis (MWCS). In total, 387 720 MWCS have been computed between 20 s and 80 s lapse time to obtain relative velocity changes (dv/v). All dv/v are then inverted using a Bayesian weighted least square procedure. Depending on the smoothing weight used during the inversion, seasonal to long term trends can be evidenced. The results show clear and stable trends in the data. We present possible causes explaining these trends and abrupt changes of dv/v by showing modelled (GLDAS) and observed climatic data together with anthropogenic observables. A combination of climatic (warmer surface temperatures, less rainfall) and anthropogenic (more population, more irrigated land) factors are the most probable causes of the progressive relative increase of seismic velocities under the Gräfenberg array. We interpret these results as a progressive depletion of the water resources in the large karstified Malm reservoir (Late Jurassic) below the array.

  5. Improved GIA Correction and Antarctic Contribution to Sea-level Rise Observed by GRACE

    Ivins, Erik; James, Thomas; Wahr, John; Schrama, Ernst; Landerer, Felix; Simon, Karen

    2013-04-01

    -65 Gt/yr. The new correction increases the solved-for ice mass imbalance of Antarctica to -57 ± 34 Gt/yr. The revised GIA correction is smaller than past GRACE estimates by about 50 to 90 Gt/yr. The new upper bound to sea-level rise from AIS mass loss averaged over the time span 2003.0 - 2012.0 is about 0.16 ± 0.09 mm/yr. We discuss the differences in spatio-temporal character of the gain-loss regimes of Antarctica over the observing period.

  6. ECOLES: a Citizen Observers network engaging communities to map climate change at the local level

    Thejll, Peter; Walker, Nicholas; Sandholt, Inge; Brown, Ian; Solberg, Rune; Suwala, Jason; Kelly, Richard; Tangen, Helge; Berglund, Robin; Dean, Andy; Engset, Rune; Siewertsen, Bjarne

    2016-04-01

    Engaging people in environmental studies is an important way to bring across awareness of expected future climate changes, and also a way to measure environmental change in ways that are better or complementary to remote sensing methods. With a hands-on approach, people are more likely to embrace the idea that climate change is occurring, and with modern technologies it is possible to collect quite stunning amounts of relevant data. We suggest several national activities tailored to conditions in each of the participating countries and also to existing national CO-projects. The project focuses on gathering data on biological changes, on weather, and on snow-pack information in Nordic countries as well as Greenland and Canada. Data will be gathered with existing equipment (mobile phones and internet-connected weather stations) and the project provides the means for collation of data into a database for dissemination and quality control. Numerical data collected by small non-professional weather stations or mobile phones with sensors are not directly useful quantitatively for e.g. numerical weather prediction without validation of data quality, but with validation there is a huge untapped potential due to the number of observers. Students are a central part of the project, which also seeks to engage people out and about in nature, and people with their own weather stations or other environmental data-collection activities, as well as passive data collection from mobile phone data sensors in people's bags and pockets. Appropriate software, educational and training materials will be designed with end-users in mind; school-age materials will be produced in the appropriate languages (e.g. Kalaallisut for COs of school age in Greenland).

  7. Effect of action observation therapy on daily activities and motor recovery in stroke patients

    Mei-Hong Zhu

    2015-09-01

    Conclusion: Action observation therapy significantly improves upper extremity motor function and performance of activities of daily living, and alleviates upper limb spasticity in patients with stroke.

  8. High levels of ultraviolet radiation observed by ground-based instruments below the 2011 Arctic ozone hole

    G. Bernhard

    2013-06-01

    Full Text Available Greatly increased levels of ultraviolet (UV radiation were observed at thirteen Arctic and sub-Arctic ground stations in the spring of 2011 when the ozone abundance in the Arctic stratosphere dropped to the lowest amounts on record. Measurements of the noontime UV Index (UVI during the low-ozone episode exceeded the climatological mean by up to 77% at locations in the western Arctic (Alaska, Canada, Greenland and by up to 161% in Scandinavia. The UVI measured at the end of March at the Scandinavian sites was comparable to that typically observed 15–60 days later in the year when solar elevations are much higher. The cumulative UV dose measured during the period of the ozone anomaly exceeded the climatological mean by more than two standard deviations at 11 sites. Enhancements beyond three standard deviations were observed at seven sites and increases beyond four standard deviations at two sites. At the western sites, the episode occurred in March when the Sun was still low in the sky, limiting absolute UVI anomalies to less than 0.5 UVI units. At the Scandinavian sites, absolute UVI anomalies ranged between 1.0 and 2.2 UVI units. For example, at Finse, Norway, the noontime UVI on 30 March was 4.7 while the climatological UVI is 2.5. Although a UVI of 4.7 is still considered moderate, UV levels of this amount can lead to sunburn and photokeratitis during outdoor activity when radiation is reflected upward by snow towards the face of a person or animal. At the western sites, UV anomalies can be well explained with ozone anomalies of up to 41% below the climatological mean. At the Scandinavian sites, low ozone can only explain a UVI increase by 50–60%. The remaining enhancement was mainly caused by the absence of clouds during the low-ozone period.

  9. Physical activity level of school children of age 10-13 years

    Ronghe, Dr. Rashmi N; Gotmare, Dr. Neha A; Kawishwar, Dr. Shraddha

    2016-01-01

    Aim: To assess physical activity level of school children of age 10-13 years.Objectives: To assess and grade physical activity level in children of age 10-13 years using Physical Activity Questionnaire for Children (PAQ-C) classified into: Light Physical activity; Moderate Physical activity; Moderate to vigorous Physical activity and High Physical activity.Methodology: This is Questionnaire based survey study which was conducted on 100 school going children of 10-13 years who were present on ...

  10. Observed sea-level rise in the north Indian Ocean coasts during the past century

    Unnikrishnan, A.S.

    -level rise is one of the good indicators of global warming. Rise in sea level occurs mainly through melting of glaciers, thermal expansion due to ocean warming and some other processes of relatively smaller magnitudes. Sea level rise is a global... or by remote forcing, cause changes in sea level. Besides, interannual events such as El Nino also show their signatures on sea level. Measurement of sea level Measurement of sea level started since 1870’s by using instruments known as tide gauges...

  11. Relationships of sexual activities in estrous cows to different frequencies of observation and pedometer measurements.

    Pennington, J A; Albright, J L; Callahan, C J

    1986-11-01

    Sexual activities were observed continuously for 120 h in Holstein dairy cows during moderate climate. Pedometer measurements of motor activity were correlated with total activities initiated, total activities received, mounts received, and time in estrus. Twelve of 14 individual sexual activities also were correlated on a within-cow basis with pedometer-measured increases in motor activity; disoriented mounts and licking front were not correlated to pedometer increases. Although observations of four 1-h and four or six 30-min observations accounted for greater variation, pedometer increases in activity accounted for as much variation in total sexual activities as periodic observations of 30 min or 1 h for 1 to 3 X /d. Combining periodic observations with pedometer measurements resulted in greater coefficients of determination for analyses of sexual activities than with each individual factor. Sexual activities and pedometer increases also were correlated positively with body condition score and day postpartum, and they were correlated negatively with milk production and body weight change since calving. Although mounting and total sexual activities were shifted significantly from expected on a quartile basis, shifts were probably not of practical significance and provided little evidence for more frequent occurrence of estrous activity during nocturnal periods. Rather, the most marked decrease in mounting and total sexual activities occurred at milking and feeding times, indicating that dairy farmers should be more concerned with disruptions of activities by management practices rather than nocturnal occurrence of estrus. PMID:3805464

  12. Photocatalytically Active Oligomeric Graphitic Carbon Nitride: Conformational Flexibility, Electronic Levels, Carrier Localization

    Blum, Volker; Lau, Vincent; Botari, Tiago; Huhn, William; Lotsch, Bettina V.

    2015-03-01

    Polymers consisting of bridged heptazine units (often called ``graphitic carbon nitride'' or ``g-C3N4'') show considerable promise as photocatalysts for solar hydrogen evolution. Recent experimental evidence suggests that oligomeric rather than fully polymerized ``g-C3N4'' exhibits increased intrinsic photocatalytic activity. Using density-functional theory (DFT; van der Waals corrected PBE functional for conformers, hybrid DFT and GW for electronic levels), we show that considerable conformational flexibility exists for the heptazine trimers and tetramers. Analysis of HOMO and LUMO locations as well as trends in photocatalytic activity among heptazine oligomers and polymers reveals the NH2 groups of the oligomers as potential charge-transfer sites. We show that conformational variations of the oligomers can lead to significant, electrostatically motivated carrier localization effects. We suggest that NH2 side groups and the intrinsic conformational variations of the oligomeric species lead to the observed enhanced catalytic activity.

  13. Modeling interseismic deformation field of North Tehran Fault extracted from precise leveling observation

    Amighpey, Masoome; Voosoghi, Behzad; Arabi, Siyavash

    2016-06-01

    The North Tehran Fault (NTF) stands out as a major active thrust fault running for approximately 110 km north of Tehran, the capital province of Iran. It has been the source of several major historical earthquakes in the past, including those in 958, 1665, and 1830. In this paper, interseismic strain accumulation on the NFT was investigated using precise leveling measurements obtained over the time frame 1997-2005. The relationship between surface deformation field and interseismic deformation models was evaluated using simulated annealing optimization in a Bayesian framework. The results show that the NTF fault follows an elastic dislocation model creep at a rate of 2.5 ± 0.06 mm/year in the eastern part and 6.2 ± 0.04 mm/year in the western part. Moreover, the locking depth of the fault was evaluated to be ± 1.1 km in the eastern part and 1.3 ± 0.2 km in the western part.

  14. Negative relationships between erythrocyte Ca-pump activity and lead levels in mothers and newborns.

    Campagna, D; Huel, G; Hellier, G; Girard, F; Sahuquillo, J; Fagot-Campagna, A; Godin, J; Blot, P

    2000-12-01

    Lead poisoning induces hematological, gastrointestinal and neurological dysfunctions. One of the potential mechanisms is the inhibition of calcium-pump (Ca-pump), a transport protein. We investigated the effects of an environmental low lead exposure on Ca-pump activity in 247 mothers and their newborns. Maternal and cord blood, and newborn and mother hair, were sampled at delivery. Geometric means for mother and cord blood lead (Pb-B), and for mother and newborn hair lead (Pb-H), were 6.3 and 4.8 microg/dl, and 1.7 and 1.1 microg/g. Means for mother and cord basal Ca-pump activities were 2,442 and 2,675 nM/mg/hr. Mother enzymatic activity was negatively related to her Pb-B and Pb-H and to the cord Pb-B and newborn Pb-H levels. Newborn enzymatic activity was negatively related to his Pb-H level only. Adjustment for gestational age, child's sex, mother's age at delivery, alcohol, coffee and tea consumption, and smoking habits during pregnancy did not modify these relationships. Our findings support the hypothesis that lead toxicity could be in part mediated by a reduction of Ca-pump activity. This effect could be observed at low environmental exposure, in mothers and newborns. PMID:11191638

  15. The contribution of the primary school setting and physical education lessons to children's physical activity levels

    Howells, K

    2014-01-01

    The thesis research explored children’s physical activity levels that occurred within the primary school setting. It examined the contribution that Physical Education lessons make to children’s overall measured physical activity levels within the school day. It investigated children’s perceived level of physical activity and compared this with children’s physical activity measured by accelerometers. For the purpose of the thesis research, physical activity was regarded as, “any bodily movemen...

  16. Low-level radioactive waste activities in Texas

    In September 1982, the Texas Low-Level Radioactive Waste Disposal Authority began the process for the selection, construction, and operation of a low-level radioactive waste disposal facility in Texas. The statute creating the Authority is a very comprehensive law which calls for the orderly completion of a step-by-step process in the development of the disposal facility. The organization of the Authority and its use of external resources, both professional organizations and citizens groups, are functioning extremely well in the performance of the Authority's objectives. Continued success will lead to the development and operation of a low-level radioactive waste disposal site in Texas prior to 1988

  17. Microearthquake Observations in a 7-level Vertical Seismic Array in the TCDP Borehole, Taiwan

    Lin, Y.; Wu, H.; Ma, K.; Oye, V.; Tanaka, H.

    2007-12-01

    In order to obtain in-situ information on slip zones of the 1999 Chi-Chi earthquake, the Taiwan Chelungpu-fault drilling project (TCDP) drilled two vertical boreholes (A, B) and a branch hole (C) through the fault where a displacement of 12 m had occurred. The TCDP hole A is 2 km deep, and a slip zone was identified at a depth of 1111 m. Hole B (with side track, hole C) is 1.3 km deep with an identified slip zone at 1138 m. In July 2006, a 7- level vertical borehole seismic array (TCDP BHS) was installed in hole A covering a depth from 946 m to 1274 m with 50- 60 m depth intervals. For this layout, three seismometers were placed in the hanging wall and footwall, respectively. The forth one is located at the depth of 1110.28 m, close to the identified slip zone. Microearthquakes with magnitude down to -0.5 were detected by the TCDP BHS. A temporary seismic array with 10 short period seismometers around the TCDP drill site was also installed to incorporate with the TCDP BHS for the precise locations of the microearthquakes. A real-time location software (MIMO) (Oye and Roth, 2003) was used to automatically determine P- and S-wave onset times, incidence and azimuth angles and locations of the microearthquakes. Regardless of the large co-seismic slip of 12 m at the drill site during the 1999 Chi-Chi earthquake, our preliminary studies do not show any close-by seismicity near the drill site after almost 8 years since the large earthquake happened. The microearthquakes clustered at a depth of 8-10 km, where the 30 degree dipping of the Chelungpu thrust fault becomes flat to a decollement of the Taiwan fold-and-thrust tectonic structure. As a continuous GPS survey did not observe post-slip at the large slip region, and as no seismicity was observed near the drill site, we suggest that the thrust belt above the decollement during the interseismic period seems to be locked. A Fluid Injection Test (FIT), pumping high pressure fluid into hole B and C with hole A as

  18. Levels of active tyrosine kinase receptor determine the tumor response to Zalypsis

    Zalypsis® is a marine compound in phase II clinical trials for multiple myeloma, cervical and endometrial cancer, and Ewing’s sarcoma. However, the determinants of the response to Zalypsis are not well known. The identification of biomarkers for Zalypsis activity would also contribute to broaden the spectrum of tumors by selecting those patients more likely to respond to this therapy. Using in vitro drug sensitivity data coupled with a set of molecular data from a panel of sarcoma cell lines, we developed molecular signatures that predict sensitivity to Zalypsis. We verified these results in culture and in vivo xenograft studies. Zalypsis resistance was dependent on the expression levels of PDGFRα or constitutive phosphorylation of c-Kit, indicating that the activation of tyrosine kinase receptors (TKRs) may determine resistance to Zalypsis. To validate our observation, we measured the levels of total and active (phosphorylated) forms of the RTKs PDGFRα/β, c-Kit, and EGFR in a new panel of diverse solid tumor cell lines and found that the IC50 to the drug correlated with RTK activation in this new panel. We further tested our predictions about Zalypsis determinants for response in vivo in xenograft models. All cells lines expressing low levels of RTK signaling were sensitive to Zalypsis in vivo, whereas all cell lines except two with high levels of RTK signaling were resistant to the drug. RTK activation might provide important signals to overcome the cytotoxicity of Zalypsis and should be taken into consideration in current and future clinical trials

  19. The prediction of induced activity levels in and around NIMROD

    Hack, R C

    1973-01-01

    Comparisons are reported between measured and predicted levels of induced radioactivity for a number of irradiation conditions. Good agreement was found between experimental measurements and fairly simple methods of prediction developed at CERN.

  20. Spirulina maxima and its effect on antioxidant activity in fructose induced oxidative stress with histopathological observations

    Jarouliya Urmila

    2015-12-01

    Full Text Available Diabetes mellitus is a metabolic disorder characterised by hyperglycemia and oxidative stress. The aim of the present study is to explore the antioxidant effect of Spirulina maxima in rat model along with the histopathological observations. Diabetes was induced by feeding 10% fructose solution orally to Wistar rats (n = 6 for 30 days, analysed for plasma blood glucose and the markers of the oxidative stress [catalase (CAT, superoxide dismutase (SOD, reduced glutathione (GSH and thiobarbituric acid reactive substances (TBARS]. These biochemical studies were associated with histopathological examination of liver and kidney sections. The microalga Spirulina maxima being rich in proteins and other essential nutrients is widely used as a food supplement. S. maxima at a dose of 5 and 10% per kg and the metformin (500 mg/kg as reference drug were given orally for 30 days to the diabetic rats. Diabetic rats showed significant (p < 0.001 elevations in plasma blood glucose, thiobarbituric acid-reactive substances and significant reduction in catalase, superoxide dismutase and reduced glutathione activity. Oral administration of 5 and 10% aqueous extract of S. maxima for 30 days restored not only of blood glucose levels but also markers of oxidative stress. Histopathological observations of tissues manifested that the S. maxima administration had the protective and therapeutic effects against fructose-induced abnormalities in diabetic rats. It is concluded that S. maxima is effective in reinstating the antioxidant activity in addition to its antidiabetic effect in type 2 diabetic rats.

  1. The higher level of complexity of K-Ras4B activation at the membrane.

    Jang, Hyunbum; Banerjee, Avik; Chavan, Tanmay S; Lu, Shaoyong; Zhang, Jian; Gaponenko, Vadim; Nussinov, Ruth

    2016-04-01

    Is nucleotide exchange sufficient to activate K-Ras4B? To signal, oncogenic rat sarcoma (Ras) anchors in the membrane and recruits effectors by exposing its effector lobe. With the use of NMR and molecular dynamics (MD) simulations, we observed that in solution, farnesylated guanosine 5'-diphosphate (GDP)-bound K-Ras4B is predominantly autoinhibited by its hypervariable region (HVR), whereas the GTP-bound state favors an activated, HVR-released state. On the anionic membrane, the catalytic domain adopts multiple orientations, including parallel (∼180°) and perpendicular (∼90°) alignments of the allosteric helices, with respect to the membrane surface direction. In the autoinhibited state, the HVR is sandwiched between the effector lobe and the membrane; in the active state, with membrane-anchored farnesyl and unrestrained HVR, the catalytic domain fluctuates reinlessly, exposing its effector-binding site. Dimerization and clustering can reduce the fluctuations. This achieves preorganized, productive conformations. Notably, we also observe HVR-autoinhibited K-Ras4B-GTP states, with GDP-bound-like orientations of the helices. Thus, we propose that the GDP/GTP exchange may not be sufficient for activation; instead, our results suggest that the GDP/GTP exchange, HVR sequestration, farnesyl insertion, and orientation/localization of the catalytic domain at the membrane conjointly determine the active or inactive state of K-Ras4B. Importantly, K-Ras4B-GTP can exist in active and inactive states; on its own, GTP binding may not compel K-Ras4B activation.-Jang, H., Banerjee, A., Chavan, T. S, Lu, S., Zhang, J., Gaponenko, V., Nussinov, R. The higher level of complexity of K-Ras4B activation at the membrane. PMID:26718888

  2. Liquid-phase adsorption of phenol onto activated carbons prepared with different activation levels

    Hsieh, C.T.; Teng, H.S.

    2000-07-01

    The paper investigates the influence of the pore size distribution of activated carbon on the adsorption of phenol from aqueous solutions. Activated carbons with different porous structures were prepared by gasifying a bituminous coal char to different extents of burn-off. The results of adsorption experiments show that the phenol capacity of these carbons does not proportionally increase with their BET surface area. This reflects the heterogeneity of the carbon surface for adsorption. The pore size distributions of these carbons were found to vary with the burn-off level. The paper demonstrates that the heterogeneity of carbon surface for the phenol adsorption can be attributed to the different energies required for adsorption in different-size micropores.

  3. Coronal upflows from edges of an active region observed with EUV Imaging Spectrometer onboard Hinode

    Kitagawa, Naomasa

    2014-01-01

    In order to better understand the plasma supply and leakage at active regions, we investigated physical properties of the upflows from edges of active region NOAA AR10978 observed with the EUV Imaging Spectrometer (EIS) onboard Hinode. Our observational aim is to measure two quantities of the outflows: Doppler velocity and electron density.

  4. Irisin levels are not affected by physical activity in patients with anorexia nervosa

    TobiasHofmann

    2014-01-01

    Full Text Available Irisin was recently identified as muscle-derived hormone that increases energy expenditure. Studies in normal weight and obese subjects reported an increased irisin expression following physical activity, although inconsistent results were observed. Increased physical activity in a subgroup of patients with anorexia nervosa (AN complicates the course of the disease. Since irisin could account for differences in clinical outcomes, we investigated irisin levels in anorexic patients with high and moderate physical activity to evaluate whether irisin differs with increasing physical activity. Hospitalized female anorexic patients (n=39 were included. Plasma irisin measured by ELISA and locomotor activity were assessed at the same time. Patients were separated into two groups (n=19/group; median excluded: moderate and high activity (6331±423 vs. 13743±1047 steps/day, p0.05, whereas body weight-adjusted total energy expenditure (46.0±1.4 vs. 41.1±1.1 kcal/kg/d, metabolic equivalents (METs, 1.9±0.1 vs. 1.7±0.1 METs/d, body weight-adjusted exercise activity thermogenesis (EAT, 1.8±0.5 vs. 0.6±0.3 kcal/kg/d, duration of exercise (18.6±4.7 vs. 6.2±3.1 min/d and body weight-adjusted non-exercise activity thermogenesis (21.6±1.0 vs. 18.8±0.8 kcal/kg/d were higher in the high activity compared to the moderate activity group (p0.05. In conclusion, the current data do not support the concept of irisin being induced by exercise, at least not under conditions of severely reduced body weight like AN.

  5. USDOE activities in low-level radioactive waste treatment

    This paper describes current research, development and demonstration (R, D and D) programs sponsored by the US Department of Energy in the area of low-level radioactive waste treatment. The US Department of Energy Low-Level Radioactive Waste Management Program is directed toward a coordinated program covering the period from low-level radioactive waste generation through the decommissioning of the disposal site. This paper addresses the treatment portion of the program. The development efforts include: mechanical methods for metal and compactible waste volume reduction; incineration of trash or other combustibles through the use of controlled air, cyclone, or molten glass furnaces; ultrafiltration, reverse osmosis, biological or chemical destruction of nitrates; adsorption treatment of low-concentration aqueous waste streams; combustion of organic liquids; and smelting of metal wastes to reduce their volume and conserve our natural resources. (author)

  6. Decoupling of ground level pressures observed in Italian volcanoes: are they driven by space weather geo-effectiveness?

    Paolo Madonia

    2014-07-01

    Full Text Available Investigations on correlation drops between near-ground atmospheric pressures measured at sea level and at higher altitudes on Italian volcanoes have been carried out. We looked for perturbations of the atmospheric pressure field driven by volcanic activity, but not excluding possible external triggers for the observed anomalies. Decorrelations between atmospheric pressures measured at Stromboli Island in stations located at different altitudes (years 2002-10 have been analysed and compared with data from other volcanic (Vesuvius and non volcanic (Mt. Soro orographic structures. We investigated as their possible triggers volcanic, meteorological and space weather parameters, with particular attention to Total Solar Irradiance (TSI, Kp index and Forbush decreases. Pressure decorrelations seems to be driven by astronomic cycles, with maxima in summer and minima in winter. A further contribution was found, seemingly assignable to TSI anomalies, with correlation minima occurring 12 hours after these but only during phases of high Sun activity. Moreover, during the same phases a main periodicity of about 27 days in pressure decorrelations was revealed by FFT analysis. This period is the same of the Sun Carrington rotation, expressing the periodic reappearance of sunspot groups on Sun’s surface. The strong similarity between recurrences of sunspot number and atmospheric pressure anomalies further supports the role of the former as a possible trigger for the latter.

  7. Evolution of the Level of Sunspot Activity in Solar CyclesⅠ. Evolution in the Descending Phase

    Jia-Long Wang

    2006-01-01

    Taking the 13-point smoothed monthly sunspot number, Ri, and the deviation of the 13 associated monthly sunspot numbers from the smoothed one, Di, as a number-pair describing the global level of sunspot activity, the evolution of the level is statistically studied for the period from the month which is just 48 months before the minimum to the minimum in the descending phase, using the observed data of Solar Cycles 10 to 22. Our results show (1) for 46 months (94%) of the studied 49 months it is found that for a given month, the distribution of the 13 pairs which come from the 13 solar cycles on a log Ri~Di plane may be fitted by a straight line with a correlation coefficient larger than the critical one at confidence levelα=5%, and for 36 months (73%) the fitting is even better, forα=1%;(2) time variations of these two parameters and their correlations in the studied period can be described respectively by functions of time, whose main trends may be expressed by a linear or simple curvilinear function; (3) the evolutionary path of the level of sunspot activity may be represented by a logarithmic function as log Ri=0.704 ln Di-0.291.

  8. Studies on levels and interactions of contact activation factors in plasma

    Summary of findings and conclusions of relevance: A part of the thesis concerns the effects of intravenous contrast media on the blood pressure and on factors of the contact activation system in the rat. The intravenous injection of dextran induced a profound and lasting fall in blood pressure, preceded by significant lowering in prekallikrein and activation factor 12. The non-ionic radiographic contrast media iohexol caused no significant alterations, neither in blood pressure, nor in levels of contact factors, whereas the ionic radiographic contrast media iodipamide had effects. It induced a rapid, but short-lived, fall in blood pressure and a small, but statistically significant reduction in the measurable amount of activation factor 12a. An observation of significance was that pretreatment of the rats with iodipamide almost blocked the dextran-induced blood pressure fall, and abolished the reduction in prekallikrein and activation factor 12a. It is concluded that the ionic radiographic contrast media used was capable of blocking dextran shock in the rat by preventing an activation of contact activation system. 130 refs., 5 figs

  9. Smelling lavender and rosemary increases free radical scavenging activity and decreases cortisol level in saliva.

    Atsumi, Toshiko; Tonosaki, Keiichi

    2007-02-28

    Free radicals/reactive oxygen species are related to many biological phenomena such as inflammation, aging, and carcinogenesis. The body possesses various antioxidative systems (free radical scavenging activity, FRSA) for preventing oxidative stress, and saliva contains such activity. In the present study, we measured the total salivary FRSA induced after the smelling of lavender and rosemary essential oils that are widely used in aromatherapy. Various physiologically active substances in saliva such as cortisol, secretory IgA, and alpha-amylase activity were found to be correlated with aroma-induced FRSA. The subjects (22 healthy volunteers) sniffed aroma for 5 min, and each subject's saliva was collected immediately. FRSA was measured using 1,1-diphenyl-2-picrylhydrazyl. The FRSA values were increased by stimulation with low concentrations (1000 times dilution) of lavender or by high-concentrations (10 times dilution) of rosemary. In contrast, both lavender and rosemary stimulations decreased cortisol levels. A significant inverse correlation was observed between the FRSA values and the cortisol levels with each concentration of rosemary stimulation. No significant changes were noted in sIgA or alpha-amylase. These findings clarify that lavender and rosemary enhance FRSA and decrease the stress hormone, cortisol, which protects the body from oxidative stress. PMID:17291597

  10. Energy requirements and physical activity level of active elderly people in rural areas of Cuba

    Obesity and NIDDM are common in the Third Age and increasing in Cuba. Among the life-style changes associated with increased prevalence of obesity and its related disorders, diet and activity patterns are prime candidates. The transition to this life-style model may induce a decrease in the energy needs. There is an urgent need for tools which have been validated for measuring diet and physical activity in nutritional studies in the developing world, but also a more urgent need for reference values for the total energy requirements of healthy elderly people. Regular physical activity reduces the likelihood to develop diseases that characterise the metabolic cardiovascular syndrome. With the purpose of estimating the energy requirements, a group of 48 elderly people aged 61-74 years living in a rural mountain community was submitted to a medical, epidemiological, dietary and biochemical study of the nutritional status. Glucose intolerance was diagnosed in 40% and arterial hypertension was present in 23 % of them. Ten subjects without signs or symptoms of the metabolic cardiovascular syndrome were submitted to a measurement of the total energy expenditure by the doubly labelled water method. PAL values of 2.13 and 1.77 were measured for men and women, values which were significantly higher that the recommended value of 1.51 for elderly subjects. The total energy expenditure: The estimation of energy requirements by the energy intake or by the factorial method using the physical activity questionnaires generated values, which were 11 % and 30% lower than the values obtained by the DLW-method. The value of 1.51 x BMR for the estimation of the energy requirements of elderly subjects living in rural areas and submitted to higher levels of physical activity seems to be sub estimated

  11. Energy requirements and physical activity level of active elderly people in rural areas of China

    Obesity and NIDDM are common in the Third Age and increasing in Cuba. Among the life-style changes associated with increased prevalence of obesity and its related disorders, diet and activity patterns are prime candidates. The transition to this life-style model may induce a decrease in the energy needs. There is an urgent need for tools which have been validated for measuring diet and physical activity in nutritional studies in the developing world, but also a more urgent need for reference values for the total energy requirements of healthy elderly people. Regular physical activity reduces the likelihood to develop diseases that characterise the metabolic cardiovascular syndrome. With the purpose of estimating the energy requirements, a group of 48 elderly people aged 61-74 years living in a rural mountain community was submitted to a medical, epidemiological, dietary and biochemical study of the nutritional status. Glucose intolerance was diagnosed in 40% and arterial hypertension was present in 23 of them. Ten subjects without signs or symptoms of the metabolic cardiovascular syndrome were submitted to a measurement of the total energy expenditure by the doubly labelled water method. PAL values of 2.13 and 1. 77 were measured for men and women, values which were significantly higher that the recommended value of 1.51 for elderly subjects. The estimation of energy requirements by the energy intake or by the factorial method using the physical activity questionnaires generated values, which were 11% and 30% lower than the values obtained by the DLW-method The value of 1.51 x BMR for the estimation of the energy requirements of elderly subjects living in rural areas and submitted to higher levels of physical activity seems to be sub estimated. (author)

  12. Active Radiation Level Measurement on New Laboratory Instrument for Evaluating the Antibacterial Activity of Radioisotope

    Joh, Eunha; Park, Jang Guen [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    A disc method has been widely used to measure the antibacterial effect of chemical agents. However, it is difficult to measure the antibacterial effect of radioisotopes using a disc method. A disc method is a method for diffusing a drug by placing the drug containing disc on the medium. In this method, radioisotopes are diffused on the medium and it is difficult to measure the exact effect by radiation. Thus, new laboratory equipment needs to evaluate the antibacterial activity by the radioisotopes. In this study, we measured the radiation level of radioisotopes on a new laboratory instrument using a MCNP. A disc method has been widely used to measure the antibacterial effect of chemical agents. This method uses a drug diffusion system for the measurement of anti-bacterial antibiotics. To measure the antimicrobial activity of a radioisotope, a new type of laboratory instrument is necessary to prevent the drug from spreading. The radioisotopes are used to diagnose and treat cancer. However, studies for anti-biotical use have not progressed. The radiation of radioisotopes has the effect of killing bacteria. Before this study proceeds further, it is necessary to be able to measure the antimicrobial activity of the radioisotope easily in the laboratory. However, in this study, it was possible to measure the antimicrobial activity of the radioisotope in the laboratory using a new laboratory instrument. We intend to start evaluation studies of the antibacterial activity of specific radioisotopes. In addition, it will be possible to develop research to overcome diseases caused by bacteria in the future.

  13. Energy requirements and physical activity level of active elderly people in rural areas of Cuba

    Full text: Obesity and NIDDM are common in the Third Age and increasing in Cuba. Among the lifestyle changes associated with increased prevalence of obesity and its related disorders, diet and activity patterns are prime candidates. The transition to this lifestyle model may induce a decrease in the energy needs. There is an urgent need for tools which have been validated for measuring diet and physical activity in nutritional studies in the developing world, but also a more urgent need for reference values for the total energy requirements of healthy elderly people. Regular physical activity reduces the likelihood to develop diseases that characterize the metabolic cardiovascular syndrome. With the purpose of estimating the energy requirements, a group of 48 elderly people aged 61-74 years living in a rural mountain community was submitted to a medical, epidemiological, dietary and biochemical study of the nutritional status. Glucose intolerance was diagnosed in 40% and arterial hypertension was present in 23 % of them. Ten subjects without signs or symptoms of the metabolic cardiovascular syndrome were submitted to a measurement of the total energy expenditure by the doubly labelled water method. PAL values of 2.13 and 1.77 were measured for men and women, values which were significantly higher that the recommended value of 1.51 for elderly subjects. The total energy expenditure The estimation of energy requirements by the energy intake or by the factorial method using the physical activity questionnaires generated values, which were 11% and 30% lower than the values obtained by the DLW method. The value of 1.51xBMR for the estimation of the energy requirements of elderly subjects living in rural areas and submitted to higher levels of physical activity seems to be sub estimated. (author)

  14. Fidelity of frequency and phase entrainment of circuit-level spike activity during DBS.

    Agnesi, Filippo; Muralidharan, Abirami; Baker, Kenneth B; Vitek, Jerrold L; Johnson, Matthew D

    2015-08-01

    High-frequency stimulation is known to entrain spike activity downstream and upstream of several clinical deep brain stimulation (DBS) targets, including the cerebellar-receiving area of thalamus (VPLo), subthalamic nucleus (STN), and globus pallidus (GP). Less understood are the fidelity of entrainment to each stimulus pulse, whether entrainment patterns are stationary over time, and how responses differ among DBS targets. In this study, three rhesus macaques were implanted with a single DBS lead in VPLo, STN, or GP. Single-unit spike activity was recorded in the resting state in motor cortex during VPLo DBS, in GP during STN DBS, and in STN and pallidal-receiving area of motor thalamus (VLo) during GP DBS. VPLo DBS induced time-locked spike activity in 25% (n = 15/61) of motor cortex cells, with entrained cells following 7.5 ± 7.4% of delivered pulses. STN DBS entrained spike activity in 26% (n = 8/27) of GP cells, which yielded time-locked spike activity for 8.7 ± 8.4% of stimulus pulses. GP DBS entrained 67% (n = 14/21) of STN cells and 32% (n = 19/59) of VLo cells, which showed a higher fraction of pulses effectively inhibiting spike activity (82.0 ± 9.6% and 86.1 ± 16.6%, respectively). Latency of phase-locked spike activity increased over time in motor cortex (58%, VPLo DBS) and to a lesser extent in GP (25%, STN DBS). In contrast, the initial inhibitory phase observed in VLo and STN during GP DBS remained stable following stimulation onset. Together, these data suggest that circuit-level entrainment is low-pass filtered during high-frequency stimulation, most notably for glutamatergic pathways. Moreover, phase entrainment is not stationary or consistent at the circuit level for all DBS targets. PMID:26084905

  15. Magnetic cycles of Sun-like stars with different levels of coronal and chromospheric activity -- comparison with the Sun

    Bruevich, E A; Shimanovskaya, E V

    2016-01-01

    The atmospheric activity of the Sun and Sun-like stars is analyzed involving observations from HK-project at the Mount Wilson Observatory, the California and Carnegie Planet Search Program at the Keck and Lick Observatories and the Magellan Planet Search Program at the Las Campanas Observatory. We show that for stars of F, G and K spectral classes, the cyclic activity, similar to the 11-yr solar cycles, is different: it becomes more prominent in K-stars. Comparative study of Sun-like stars with different levels of the chromospheric and coronal activity confirms that the Sun belongs to stars with the low level of the chromospheric activity and stands apart among these stars by the minimum level of its coronal radiation and the minimum level of its variations of the photospheric flux.

  16. Online Activity Levels Are Related to Caffeine Dependency.

    Phillips, James G; Landhuis, C Erik; Shepherd, Daniel; Ogeil, Rowan P

    2016-05-01

    Online activity could serve in the future as behavioral markers of emotional states for computer systems (i.e., affective computing). Hence, this study considered relationships between self-reported stimulant use and online study patterns. Sixty-two undergraduate psychology students estimated their daily caffeine use, and this was related to study patterns as tracked by their use of a Learning Management System (Blackboard). Caffeine dependency was associated with less time spent online, lower rates of file access, and fewer online activities completed. Reduced breadth or depth of processing during work/study could be used as a behavioral marker of stimulant use. PMID:27096737

  17. Use and activity levels on newly built bicycle playgrounds

    Schipperijn, Jasper; Hansen, Christine Kier; Rask, Simon

    2015-01-01

    Increasing the use of urban green space (UGS) as well as increasing cycling could potentially help address the growing inactivity problem. Three bicycle playgrounds were designed based on a participatory process and afterwards constructed in the UGS along a cycle-route on the historic outer defence...... close to one of the sites. A future study involving objective before and after measures when a new bicycle playground is build will be needed to reveal if bicycle playgrounds can provide additional activity to its users, or ‘just’ a different type of activity, in a different location....

  18. A coincidence counting system for detection of low level activities

    A system based on coincidence counting for measuring the absolute activity of isotopes in which a gamma ray is emitted by the nucleus following the capture of the orbital electron with a known half-life is described. If the half-life of the excited state is small compared to the resolving time of the coincidence circuit, the absolute activity of the source can be determined. The system consists of two NaI(Th) crystals, a high voltage supply, 2 preamplifiers, 2 amplifiers, two single channel analyzers, one coincident unit, and three sealers

  19. Human hair neutron activation analysis: analysis on population level, mapping

    Neutron activation analysis is an outstanding analytical method having very wide applications in various fields. Analysis of human hair within last decades mostly based on neutron activation analysis is a very attractive illustration of the application of nuclear analytical techniques. Very interesting question is how the elemental composition differs in different areas or cities. In this connection the present paper gives average data and maps of various localities in the vicinity of drying-out Aral Sea and of various industrial cities in Central Asia. (author)

  20. [Dynamics of lysozyme levels in the blood serum and milk of puerperae with various functional activities of the breasts].

    Safronov, O V; Bakuleva, L P; Nesterova, A A; Babaian, S S

    1991-05-01

    The morbidity rates, ++features of lactation formation, and serum and breast milk lysozyme levels were studied in 91 parturients who showed various breast functional activity in the early postpartum period. The highest frequency of postpartum ++pyo-septic diseases was found in females with hyperlactation. There was earlier appearance of foremilk and milk in these females. Healthy mothers with higher breast functional activity exhibited the greatest levels of lysozyme in the milk and marked decreases in its levels in the blood within the first 3 days as compared to those observed in females who had normal or insufficient quantities of milk. PMID:1897671

  1. The relationship between physical activity and low back pain outcomes: a systematic review of observational studies

    Hendrick, Paul; Milosavljevic, S.; Hale, L; Hurley, D. A.; McDonough, S; Ryan, B; Baxter, G. D.

    2010-01-01

    Although clinical guidelines advocate exercise and activity in the management of non-specific low back pain (NSLBP), the link between levels of physical activity and outcomes is unclear. This systematic review investigated the relationships between free living activity levels after onset of low back pain (LBP) and measures of pain, and disability in patients with NSLBP. Cohort and cross-sectional studies were located using OVID, CINAHL, Medline, AMED, Embase, Biomed, PubMed-National Library o...

  2. Space-born and ground-based observations of a solar active region and a flare

    The Active Region (AR) 2490 has been observed from June 10 to 12, 1980 by several powerful instruments operating either on the ground (Optical and Radio) and on Solar Maximum Mission Satellite (SMM). A class 1 flare in AR 2490 was observed between June 10 at 2325 UT and June 11 at 0030 UT by the same instruments. The various observations are compared. (Auth.)

  3. Motoneuron and sensory neuron plasticity to varying neuromuscular activity levels

    Ishihara, Akihiko; Roy, Roland R.; Ohira, Yoshinobu; Edgerton, V. Reggie

    2002-01-01

    The size and phenotypic properties of the neural and muscular elements of the neuromuscular unit are matched under normal conditions. When subjected to chronic decreases or increases in neuromuscular activity, however, the adaptations in these properties are much more limited in the neural compared with the muscular elements.

  4. Corruption and Economic Activity: Micro Level Evidence from Rural Liberia

    Beekman, G.; Bulte, E.H.; Nillesen, E.E.M.

    2013-01-01

    We study how corruption affects economic activities of households in rural Liberia. A proxy of corruption of community leaders is obtained by directly monitoring the diversion of inputs associated with a development project. We measure quantities of these inputs twice; before and after the chief sto

  5. Total daily energy expenditure and activity level in anorexia nervosa.

    Casper, R C; Schoeller, D A; Kushner, R; Hnilicka, J; Gold, S T

    1991-05-01

    Clinical reports consistently comment on high physical activity for anorexia nervosa patients but provide few quantitative measurements. To assess activity, total daily energy expenditure (TDEE) by doubly labeled water, basal metabolic rate (BMR), and thermic effect of meals (TEM) were measured in six female outpatients with anorexia nervosa (67% of ideal body weight) and age-, sex-, and height-matched to six control subjects. Anorexia nervosa patients expended more energy as physical activity than did control subjects [0.084 +/- 0.012 vs 0.044 +/- 0.008 MJ/kg body wt, respectively (20.1 +/- 3.0 vs 10.5 +/- 1.9 kcal/kg body wt, respectively), P less than 0.04], although they had a lower BMR [4.17 +/- 0.37 vs 5.52 +/- 0.15 MJ/d, respectively (997 +/- 89 vs 1319 +/- 37 kcal/d, respectively), P less than 0.01]. TDEE and TEM were similar in both groups. There was a reduction in serum triiodothyronine (T3; 1.20 +/- 0.15 vs 2.04 +/- 0.13 nmol/L, respectively; P less than 0.003) and a slight reduction in serum thyroxine (T4); reverse T3, thyrotropin, free T4, serum cortisol, and adrenocorticotropin values were normal. BMR correlated with total body weight and fat-free mass. These results provide quantitative evidence for increased physical activity in anorexia nervosa despite profound underweight and hypometabolism. PMID:1850575

  6. Highlands County Energy Education Activities--High School Level.

    Allen, Rodney F., Ed.

    Presented are five instructional units, developed by the Tri-County Teacher Education Center, for the purpose of educating secondary school students on Florida's unique energy problems. Unit one provides a series of value clarification and awareness activities as an introduction to energy. Unit two uses mathematics exercises to examine energy…

  7. Okeechobee County Energy Education Activities--Middle School Level.

    Allen, Rodney F., Ed.

    Over 60 energy education activities related to mathematics, science, social studies, and English comprise this manual for middle school teachers. Included are issues for discussion, puzzles, science investigations, story writing exercises, and energy cost calculation problems. Among the topics covered in these lessons are energy consumption…

  8. Observed mean sea level changes around the North Sea coastline from 1800 to present

    Wahl, T.; Haigh, I.D.; Woodworth, P. L.; Albrecht, F.; Dillingh, D.; Jensen, J; Nicholls, R J; Weisse, R.; Wöppelmann, G.

    2013-01-01

    This paper assesses historic changes in mean sea level around the coastline of the North Sea, one of the most densely populated coasts in the world. Typically, such analyses have been conducted at a national level, and detailed geographically wider analyses have not been undertaken for about 20 years. We analyse long records (up to 200 years) from 30 tide gauge sites, which are reasonably uniformly distributed along the coastline, and: (1) calculate relative sea level trends; (2) examine the ...

  9. Is Brain Activity during Action Observation Modulated by the Perceived Fairness of the Actor?

    Etzel, Joset A; Valchev, Nikola; Gazzola, Valeria; Keysers, Christian

    2016-01-01

    Perceiving other people's actions triggers activity in premotor and parietal areas, brain areas also involved in executing and sensing our own actions. Paralleling this phenomenon, observing emotional states (including pain) in others is associated with activity in the same brain areas as activated

  10. Stock market firm-level information and real economic activity

    di Mauro, Filippo; Fornari, Fabio; Mannucci, Dario

    2011-01-01

    We provide evidence that changes in the equity price and volatility of individual firms (measures that approximate the definition of 'granular shock' given in Gabaix, 2010) are key to improve the predictability of aggregate business cycle fluctuations in a number of countries. Specifically, adding the return and the volatility of firm-level equity prices to aggregate financial information leads to a significant improvement in forecasting business cycle developments in four economic areas, at ...

  11. PHYSICAL ACTIVITY LEVEL AMONG UNIVERSITY STUDENTS: A CROSS SECTIONAL SURVEY

    Roshini Rajappan; Karthikeyan Selvaganapathy; Lola Liew

    2015-01-01

    Background and Objective: Physical inactivity is the fourth leading risk factor for global mortality. Physical inactivity levels are rising in developing countries and Malaysia is of no exception. Malaysian Adult Nutrition Survey 2003 reported that the prevalence of physical inactivity was 39.7% and the prevalence was higher for women (42.6%) than men (36.7%). In Malaysia, the National Health and Morbidity Survey 2006 reported that 43.7% (5.5 million) of Malaysian adults were physically inact...

  12. Catecholamine level and monoamino oxidase activity following irradiation

    Sheep were whole-body gamma irradiated for a period of 7 days to a total dose of 6.7 Gy. After the irradiation the sheep were destroyed the pituitary and the adrenal glands were separated as was brain tissue for the determination of catecholamines and monoamino oxidase. The results show that the reduced levels of catecholamines in the hypothalamus are probably the result of a reduced synthesis and increased degradation of catecholamines through monoaminooxidase. (M.D.)

  13. [Level of nitric oxide in the kidneys during apoptosis activation].

    Komarievtseva, I O; Orlova, O A; Blahodarenko, Ie A

    2002-01-01

    The content of nitric oxide stable metabolites in a tissue of kidneys of rats in conditions of activation of apoptosis was investigated. Research was carried out in two models: acute renal failure and a hypertrophy of a unique kidney after a unilateral nephrectomy. Detection of apoptosis was carried out by definition of DNA fragmentation. Substantial increase of the nitric oxide stable metabolites contents is revealed at activation of apoptosis in both models. Change of a ratio of the contents of nitrite--anions in relation to the general contents of NO2- + NO3- is revealed, indicating the role of peroxide processes in effect of nitric oxide and its metabolites on the cell. PMID:14964872

  14. Evaluating emergency services activity at the health district level.

    Milner, P

    2001-01-01

    We do not have good information on the incidence and prevalence of emergency conditions nor is there good research evidence on the best ways of meeting these. There are, however, some indicators for evaluating emergency services activities and we have a good framework from Donabedian for evaluation, and the important dimensions of quality specified by Maxwell. The range of emergency services covers primary care, community crisis care, ambulance services, hospital services (accident and emerge...

  15. Selenium levels and Glutathione peroxidase activity in the plasma of patients with type II diabetes mellitus.

    González de Vega, Raquel; Fernández-Sánchez, María Luisa; Fernández, Juan Carlos; Álvarez Menéndez, Francisco Vicente; Sanz-Medel, Alfredo

    2016-09-01

    Selenium, an essential trace element, is involved in the complex system of defense against oxidative stress through selenium-dependent glutathione peroxidases (GPx) and other selenoproteins. Because of its antioxidant properties, selenium or its selenospecies at appropriate levels could hinder oxidative stress and so development of diabetes. In this vein, quantitative speciation of selenium in human plasma samples from healthy and diabetic patients (controlled and non-controlled) was carried out by affinity chromatography (AF) coupled on-line to inductively coupled plasma mass spectrometry (ICP-MS) and isotope dilution analysis (IDA). Similarly, it is well known that patients with diabetes who exhibit poor control of blood glucose show a decreased total antioxidant activity. Thus, we evaluated the enzymatic activity of GPx in diabetic and healthy individuals, using the Paglia and Valentine enzymatic method, observing a significant difference (ptype II diabetes mellitus patients. PMID:27473831

  16. Level of participation among the audience attended primary education training using group observation method.

    K., Srinivasan

    2007-01-01

    The article provides a detailed analysis of the teachers who attended the training for primary education viewed pre-recorded cassette using Group Observation method. First the paper discusses detailed methodology on group observation and in the second part the findings suggests that for better production of any video Programme for training the teachers should contain innovative and novel approaches.

  17. The observation of serum cholyglycine levels in patients with intrahepatic cholestasis of pregnancy

    To explore the clinical significance of empty abdominal serum Cholyglycine(CG) levels on the diagnosis of patient with Intrahepatic Cholestasis of Pregnancy(ICP), the serum levels of CG, TBA, TBIL and ALT in 400 normal pregnant women and in 87 pregnant patients with ICP were analyzed retrospectively. The results showed that the serum CG levels of patients with ICP were significant higher than that of normal control (P<0.001). The positive rate of serum CG was 100%. The serum levels of TBA, TBIL and ALT in patients with ICP were slightly higher than that of normal controls. The positive rates of TBA, TBIL and ALT were 36.5%, 12.2% and 35.6% respectively. The serum CG levels may be regarded as an economical and sensitive indicator in diagnosis of patients with ICP in the earlier stage. (authors)

  18. Advanced MicroObserver UGS integration with and cueing of the BattleHawk squad level loitering munition and UAV

    Steadman, Bob; Finklea, John; Kershaw, James; Loughman, Cathy; Shaffner, Patti; Frost, Dean; Deller, Sean

    2014-06-01

    Textron's Advanced MicroObserver(R) is a next generation remote unattended ground sensor system (UGS) for border security, infrastructure protection, and small combat unit security. The original MicroObserver(R) is a sophisticated seismic sensor system with multi-node fusion that supports target tracking. This system has been deployed in combat theaters. The system's seismic sensor nodes are uniquely able to be completely buried (including antennas) for optimal covertness. The advanced version adds a wireless day/night Electro-Optic Infrared (EOIR) system, cued by seismic tracking, with sophisticated target discrimination and automatic frame capture features. Also new is a field deployable Gateway configurable with a variety of radio systems and flexible networking, an important upgrade that enabled the research described herein. BattleHawkTM is a small tube launched Unmanned Air Vehicle (UAV) with a warhead. Using transmitted video from its EOIR subsystem an operator can search for and acquire a target day or night, select a target for attack, and execute terminal dive to destroy the target. It is designed as a lightweight squad level asset carried by an individual infantryman. Although BattleHawk has the best loiter time in its class, it's still relatively short compared to large UAVs. Also it's a one-shot asset in its munition configuration. Therefore Textron Defense Systems conducted research, funded internally, to determine if there was military utility in having the highly persistent MicroObserver(R) system cue BattleHawk's launch and vector it to beyond visual range targets for engagement. This paper describes that research; the system configuration implemented, and the results of field testing that was performed on a government range early in 2013. On the integrated system that was implemented, MicroObserver(R) seismic detections activated that system's camera which then automatically captured images of the target. The geo-referenced and time-tagged MicroObserver

  19. Using the EXIST Active Shields for Earth Occultation Observations of X-ray Sources

    Wilson, Colleen. A.; Fishman, G. J.; Hong, J. -S.; Grindlay, J.E.; H. Krawczynski(Department of Physics, Washington University, St. Louis, MO 63130, USA)

    2005-01-01

    The EXIST active shields, planned for the main detectors of the coded aperture telescope, will have approximately 15 times the area of the BATSE detectors, and they will have a good geometry on the spacecraft for viewing both the leading and trailing Earth's limb for occultation observations. These occultation observations will complement the imaging observations of EXIST and can extend them to higher energies. Earth occultation observations of the hard X-ray sky with BATSE on the Compton Gam...

  20. Ecological concerns following Superstorm Sandy: stressor level and recreational activity levels affect perceptions of ecosystem

    Burger, Joanna

    2014-01-01

    Coastal habitats are vulnerable to storms, and with increasing urbanization, sea level rise, and storm frequency, some urban populations are at risk. This study examined perceptions of respondents in coastal and central New Jersey to Superstorm Sandy, including: 1) concerns about ecological resources and effects (open-ended question), 2) information sources for ecology of the coast (open-ended), and 3) ratings of a list of ecological services as a function of demographics, location (coastal, ...

  1. Objectively-Measured Physical Activity Levels in Physical Education among Homeschool Children

    Swenson, Sarah; Pope, Zachary; Zeng, Nan

    2016-01-01

    Despite a growing population of homeschool children in the United States, little is known regarding their physical activity (PA) levels. Without access to physical education, homeschool children may engage in inadequate PA levels. The purpose of this study was to objectively examine the activity levels of homeschool students participating in a…

  2. Non-LTE Inversion of Spectropolarimetric and Spectroscopic Observations of a Small Active-region Filament Observed at the VTT

    Schwartz, P.; Balthasar, H.; Kuckein, C.; Koza, J.; Gömöry, P.; Rybák, J.; Kučera, A.; Heinzel, P.

    2016-04-01

    An active region mini-filament was observed by VTT simultaneously in the HeI 10 830 Å triplet by the TIP 1 spectropolarimeter, in Hα by the TESOS Fabry-Pérot interferometer, and in Ca II 8542 Å by the VTT spectrograph. The spectropolarimetric data were inverted using the HAZEL code and Hα profiles were modelled solving a NLTE radiative transfer in a simple isobaric and isothermal 2D slab irradiated both from bottom and sides. It was found that the mini-filament is composed of horizontal fluxtubes, along which the cool plasma of T˜10 000 K can flow by very large - even supersonic - velocities.

  3. The impact of sport and active recreation injuries on physical activity levels at 12 months post-injury.

    Andrew, N; Wolfe, R; Cameron, P; Richardson, M; Page, R; Bucknill, A; Gabbe, B

    2014-04-01

    The aim of this study was to evaluate the impact of serious sport and active recreation injury on 12-month physical activity levels. Adults admitted to hospital with sport and active recreation-related injuries, and captured by the Victorian Orthopaedic Trauma Outcomes Registry were recruited to the study. Changes between preinjury and 12 month post-injury physical activity was assessed using the short International Physical Activity Questionnaire (IPAQ). Independent demographic, injury, and hospital variables were assessed for associations with changes in physical activity levels, using multivariate linear regression. A total of 324 patients were recruited, of which 98% were followed up at 12 months. Mean short IPAQ scores decreased from 7650 METS (95% CI: 7180, 8120) preinjury to 3880 METS; (95% CI: 3530, 4250) post-injury, independent of functional recovery. Education level and occupation group were the only variables independently associated with changes in physical activity levels post-injury. These results highlighted that sport and active recreation injuries lead to significant reductions in physical activity levels. Hence, the prevention of sport and active recreation injuries is important when considering promotion of activity at a population level. PMID:22937749

  4. The relationship between postnatal depression, sociodemographic factors, levels of partner support, and levels of physical activity

    Saligheh, Maryam; Rooney, Rosanna M.; McNamara, Beverley; Kane, Robert T.

    2014-01-01

    Background: postnatal depression (PND) is defined as a psychological mood disorder that occurs in a mother within 6 weeks of her giving birth. It refers to an episode that causes mood disturbance and it could begin in, or extend into, the postpartum period. It is thought to have a high impact upon the mother's health as well as the family's functioning and the child's development. Socio-demographic, psych-social, and physical activity factors may all contribute to postpartum mood and ability ...

  5. Is Brain Activity during Action Observation Modulated by the Perceived Fairness of the Actor?

    Etzel, Joset A.; Nikola Valchev; Valeria Gazzola; Christian Keysers

    2016-01-01

    Perceiving other people's actions triggers activity in premotor and parietal areas, brain areas also involved in executing and sensing our own actions. Paralleling this phenomenon, observing emotional states (including pain) in others is associated with activity in the same brain areas as activated when experiencing similar emotions directly. This emotion perception associated activity has been shown to be affected by the perceived fairness of the actor, and in-group membership more generally...

  6. Present day sea level changes: observations and climatic causes; Les variations actuelles du niveau de la mer: observations et causes climatiques

    Lombard, A. [Centre National d' Etudes Spatiales (CNES), Lab. d' Etudes en Geophysiques et Oceanographie Spatiale (LEGOS-Cnes), 31 - Toulouse (France)

    2007-11-15

    After a few thousand years of relative stability, sea level has risen of about 20 cm since the beginning of the 20. century. It currently rises at an average rate of about 3 mm/yr in response to global warming. About half of this rate is directly attributed to thermal expansion of sea water due to ocean warming, while the other half is mainly due to the melting of mountain glaciers and ice sheets. Satellite observations show that sea level rise is highly non-uniform. (author)

  7. Maxey Flats low-level waste disposal site closure activities

    The Maxey Flats Radioactive Waste Disposal Facility in Fleming County, Kentucky is in the process of being closed. The facility opened for commercial business in the spring of 1963 and received approximately 4.75 million cubic feet of radioactive waste by the time it was closed in December of 1977. During fourteen years of operation approximately 2.5 million curies of by-product material, 240,000 kilograms of source material, and 430 kilograms of special nuclear material were disposed. The Commonwealth purchased the lease hold estate and rights in May 1978 from the operating company. This action was taken to stabilize the facility and prepare it for closure consisting of passive care and monitoring. To prepare the site for closure, a number of remedial activities had to be performed. The remediation activities implemented have included erosion control, surface drainage modifications, installation of a temporary plastic surface cover, leachate removal, analysis, treatment and evaporation, US DOE funded evaporator concentrates solidification project and their on-site disposal in an improved disposal trench with enhanced cover for use in a humid environment situated in a fractured geology, performance evaluation of a grout injection demonstration, USGS subsurface geologic investigation, development of conceptual closure designs, and finally being added to the US EPA National Priority List for remediation and closure under Superfund. 13 references, 3 figures

  8. Warm-Up Activities of Middle and High School Band Directors Participating in State-Level Concert Band Assessments

    Ward, Justin P.; Hancock, Carl B.

    2016-01-01

    The purpose of this study was to examine the warm-ups chosen by concert band directors participating in state-level performance assessments. We observed 29 middle and high school bands and coded the frequency and duration of warm-up activities and behaviors. Results indicated that most bands rehearsed music and played scales, long tones, and…

  9. Effect of CALIPSO Cloud Aerosol Discrimination (CAD) Confidence Levels on Observations of Aerosol Properties near Clouds

    Yang, Weidong; Marshak, Alexander; Varnai, Tamas; Liu, Zhaoyan

    2012-01-01

    CALIPSO aerosol backscatter enhancement in the transition zone between clouds and clear sky areas is revisited with particular attention to effects of data selection based on the confidence level of cloud-aerosol discrimination (CAD). The results show that backscatter behavior in the transition zone strongly depends on the CAD confidence level. Higher confidence level data has a flatter backscatter far away from clouds and a much sharper increase near clouds (within 4 km), thus a smaller transition zone. For high confidence level data it is shown that the overall backscatter enhancement is more pronounced for small clear-air segments and horizontally larger clouds. The results suggest that data selection based on CAD reduces the possible effects of cloud contamination when studying aerosol properties in the vicinity of clouds.

  10. Low-Level Laser Therapy Activates NF-kB via Generation of Reactive Oxygen Species in Mouse Embryonic Fibroblasts

    Aaron C-H Chen; Arany, Praveen R.; Ying-Ying Huang; Tomkinson, Elizabeth M.; Sharma, Sulbha K.; Kharkwal, Gitika B.; Taimur Saleem; David Mooney; Yull, Fiona E.; Timothy S Blackwell; Hamblin, Michael R.

    2011-01-01

    BACKGROUND: Despite over forty years of investigation on low-level light therapy (LLLT), the fundamental mechanisms underlying photobiomodulation at a cellular level remain unclear. METHODOLOGY/PRINCIPAL FINDINGS: In this study, we isolated murine embryonic fibroblasts (MEF) from transgenic NF-kB luciferase reporter mice and studied their response to 810 nm laser radiation. Significant activation of NF-kB was observed at fluences higher than 0.003 J/cm(2) and was confirmed by Western blot ana...

  11. Dueling Volcanoes: How Activity Levels At Kilauea Influence Eruptions At Mauna Loa

    Trusdell, F.

    2011-12-01

    The eruption of Kilauea at Pu`u `O`o is approaching its 29th anniversary. During this time, Mauna Loa has slowly inflated following its most recent eruption in 1984. This is Mauna Loa's longest inter-eruptive interval observed in HVO's 100 years of operation. When will the next eruption of Mauna Loa take place? Is the next eruption of Mauna Loa tied to the current activity at Kilauea? Historically, eruptive periods at Kilauea and Mauna Loa volcanoes appear to be inversely correlated. In the past, when Mauna Loa was exceptionally active, Kilauea Volcano was in repose, recovery, or in sustained lava lake activity. Swanson and co-workers (this meeting) have noted that explosive activity on Kilauea, albeit sporadic, was interspersed between episodes of effusive activity. Specifically, Swanson and co-workers note as explosive the time periods between 300 B.C.E.-1000 C.E and 1500-1800 C.E. They also point to evidence for low magma supply to Kilauea during these periods and few flank eruptions. During the former explosive period, Mauna Loa was exceedingly active, covering approximately 37% of its surface or 1882 km2, an area larger than Kilauea. This period is also marked by summit activity at Mauna Loa sustained for 300 years. In the 1500-1800 C.E. period, Mauna Loa was conspicuously active with 29 eruptions covering an area of 446 km2. In the late 19th and early 20th century, Kilauea was dominated by nearly continuous lava-lake activity. Meanwhile Mauna Loa was frequently active from 1843 C.E. to 1919 C.E., with 24 eruptions for an average repose time of 3.5 years. I propose that eruptive activity at one volcano may affect eruptions at the other, due to factors that impact magma supply, volcanic plumbing, and flank motion. This hypothesis is predicated on the notion that when the rift zones of Kilauea, and in turn its mobile south flank, are active, Mauna Loa's tendency to erupt is diminished. Kilauea's rift zones help drive the south flank seaward, in turn, as Mauna

  12. Congruent and Incongruent Corticospinal Activations at the Level of Multiple Effectors.

    Sartori, Luisa; Betti, Sonia; Perrone, Chiara; Castiello, Umberto

    2015-10-01

    Motor resonance is defined as the subliminal activation of the motor system while observing actions performed by others. However, resonating with another person's actions is not always an appropriate response: In real life, people do not just imitate but rather respond in a suitable fashion. A growing body of neurophysiologic studies has demonstrated that motor resonance can be overridden by complementary motor responses (such as preparing a precision grip on a small object when seeing an open hand in sign of request). In this study, we investigated the relationship between congruent and incongruent corticospinal activations at the level of multiple effectors. The modulation of motor evoked potentials evoked by single-pulse TMS over the motor cortex was assessed in upper and lower limb muscles of participants observing a soccer player performing a penalty kick straight in their direction. Study results revealed a double dissociation: Seeing the soccer player kicking the ball triggered a motor resonance in the observer's lower limb, whereas the upper limb response afforded by the object was overridden. On the other hand, seeing the ball approaching the observers elicited a complementary motor activation in upper limbs while motor resonance in lower limbs disappeared. Control conditions showing lateral kicks, mimicked kicks, and a ball in penalty area were also included to test the motor coding of object affordances. Results point to a modulation of motor responses in different limbs over the course of action and in function of their relevance in different contexts. We contend that ecologically valid paradigms are now needed to shed light on the motor system functioning in complex forms of interaction. PMID:26102231

  13. Hubble and Keck Telescope Observations of Active Asteroid 288P/300163 (2006 VW139)

    Agarwal, Jessica; Weaver, Harold; Mutchler, Max; Larson, Stephen

    2015-01-01

    We present Hubble Space Telescope and Keck 10 meter telescope observations of active asteroid 288P/300163 (2006 VW139) taken to examine ejected dust. The nucleus is a C-type object with absolute magnitude $H_V$ = 17.0$\\pm$0.1 and estimated diameter $\\sim$2.6 km (for assumed visual geometric albedo $p_V$ = 0.04). Variations in the brightness of the nucleus at the 10% to 15% level are significant in both 2011 December and 2012 October but we possess too few data to distinguish variations caused by activity from those caused by rotation. The dust scattering cross-section in 2011 December is $\\sim$40 km$^2$, corresponding to a dust mass $\\sim$9$\\times$10$^6$ kg (88 $\\mu$m mean particle radius assumed). The full width at half maximum of the debris sheet varies from $\\sim$100 km near the nucleus to $\\sim$1000 km 30arcsec (40,000 km) east of it. Dust dynamical models indicate ejection speeds between 0.06 and 0.3 m s$^{-1}$, particle sizes between 10 and 300 $\\mu$m and an inverse square-root relation between particle...

  14. Challenge to high-activity-level water treatment by adsorbents

    There are over 280,000 tonnes of contaminated water in the damaged Fukushima Daiichi Nuclear Plant site in various tanks and barges and a large amount of contaminated water is now producing at the rate of several tonnes/day owing to inevitable cooling of the reactor cores. SARRY (Simplified Active Water Retrieve and Recovery System) and ALPS (Advanced Liquid Processing System) are installed to remove Cs and multi-elements respectively utilizing ion exchangers (zeolite, crystalline silicon titanate, and metal ferrocyanides) from contaminated water. The author continues efforts to find effective and selective adsorbents for Cs and Sr by measuring partition data, adsorption isotherms and adsorption rate referring with chemical structure elucidated from X-ray diffraction and SEM techniques. The obtained data are presented. (S. Ohno)

  15. The relationship between postnatal depression, sociodemographic factors, levels of partner support, and levels of physical activity

    RosannaMaryRooney; BeverleyMcNamara

    2014-01-01

    Background: postnatal depression (PND) is defined as a psychological mood disorder that occurs in a mother within six weeks of her giving birth. It refers to an episode that causes mood disturbance and it could begin in, or extend into, the postpartum period. It is thought to have a high impact upon the mother’s health as well as the family’s functioning and the child’s development. Socio-demographic, psych-social, and physical activity factors may all contribute to postpartum mood and abilit...

  16. Does activity space size influence physical activity levels of adolescents?—A GPS study of an urban environment

    Lee, Nolan C.; Voss, Christine; Frazer, Amanda D.; Hirsch, Jana A.; McKay, Heather A; Winters, Meghan

    2015-01-01

    Background Physical activity (PA) is closely linked with child and youth health, and active travel may be a solution to enhancing PA levels. Activity spaces depict the geographic coverage of one's travel. Little is known about activity spaces and PA in adolescents. Objective To explore the relation between adolescent travel (using a spatial measure of activity space size) and daily moderate-to-vigorous PA (MVPA), with a focus on school days. Methods We used Global Positioning Systems to manua...

  17. Levels for the specific activity at disposing low-level contaminated municipal wastes

    Using radioecological models, nuclide specific values were calculated for the specific activity of low contaminated radioactive waste, which is disposed in conventional waste deposits or burned in incineration plants. The calculation of these values is based on a limit of 10 μSv effective dose in one year, i.e. effective dose possibly resulting from waste disposal or burning should not exceed a 'de-minimis'-value of some 10 μSv per year. The applied radioecological models describe exposure of the public by direct radiation, inhalation and ingestion for the operational period of a deposit or an incineration plant, but also cover post-operational scenarios, collecting and sorting of waste and road accidents of the waste-truck. Referring to the dose limit of 10 μSv/a, a value for the specific activity of waste was calculated for each scenario and each radionuclide considered. The smallest of these values for a radionuclide, the 'basic value' was rounded to a 'reference value'. For about 600 radionuclides reference values were derived. About 90% of the reference values are ranging between 1 and 1 000 Bq/g. For about 90% of the radionuclides direct radiation or inhalation at the deposit proved to be the critical path of exposure. (orig.)

  18. Levels for the specific activity at disposing low-level contaminated municipal wastes

    Using radioecological models, nuclide-specific ''basic values'' were established for the specific activity of radioactive contaminated waste. These basic values were determined in order to avoid dose equivalents of more than 10 μSv/a (de minimis concept) when disposing the waste in conventional waste deposits or burning it in incineration plants. The basic values vary within 16 orders of magnitude, ranging between 4.3E-02 Bq/g for Cm-250 and 2.2E+14 Bq/g for Po-212. About 82% of the basic values are between 1 Bq/g und 1000 Bq/g. The critical exposure for most of the radionuclides is that from direct radiation or inhalation at the slag-deposit. For 54% of the radionuclides the basic value for the specific activity of waste is lower at least by a factor of 10 than the 10-4-fold value per gram of the release limit (German Radiation Protection Ordinance). Appropriate nuclide-specific and dose-related limits were derived from these basic values. The respective limits are ranging between 1E-01 Bq/g and 1E+07 Bq/g. About 95% of the limits are between 1 Bq/g and 1000 Bq/g. (orig./HP)

  19. Relationship of the disease activity between ferritin levels in patients with systemic lupus erythematosus

    ÇETİNKAYA, Ramazan; Ali Rıza ODABAŞ; SELÇUK, Yılmaz

    2001-01-01

    Ferritin is an acute phase reactant which indicates serum iron storage. Its serum levels increase 10 to 100 folds responding to inflammatory stimulation. In parallel to decreasing of active of disease, levels of ferritin decrease. To investigate the relationship between serum ferritin and disease activity in systemic lupus erythematosus (SLE), we enrolled 20 patients with SLE (16 female, 4 males and mean ages: 26.6 ± 7.8 (14-45) years). The serum ferritin levels were detected in active period...

  20. The contribution of former work-related activity levels to predict physical activity and sedentary time during early retirement: moderating role of educational level and physical functioning.

    Delfien Van Dyck

    Full Text Available The transition to retirement introduces a decline in total physical activity and an increase in TV viewing time. Nonetheless, as more time becomes available, early retirement is an ideal stage to implement health interventions. Therefore, knowledge on specific determinants of physical activity and sedentary time is needed. Former work-related physical activity has been proposed as a potential determinant, but concrete evidence is lacking. The aim of this study was to examine if former work-related sitting, standing, walking or vigorous activities predict physical activity and sedentary time during early retirement. Additionally, moderating effects of educational level and physical functioning were examined.In total, 392 recently retired Belgian adults (>6 months, <5 years completed the International Physical Activity Questionnaire, the SF-36 Health Survey and a questionnaire on sociodemographics and former work-related activities. Generalized linear regression analyses were conducted in R. Moderating effects were examined by adding cross-products to the models.More former work-related sitting was predictive of more screen time during retirement. Lower levels of former work-related vigorous activities and higher levels of former work-related walking were associated with respectively more cycling for transport and more walking for transport during retirement. None of the predictors significantly explained passive transportation, cycling and walking for recreation, and leisure-time moderate-to-vigorous physical activity during retirement. Several moderating effects were found, but the direction of the interactions was not univocal.Former-work related behaviors are of limited importance to explain physical activity during early retirement, so future studies should focus on other individual, social and environmental determinants. Nonetheless, adults who previously had a sedentary job had higher levels of screen time during retirement, so this is an

  1. The Contribution of Former Work-Related Activity Levels to Predict Physical Activity and Sedentary Time during Early Retirement: Moderating Role of Educational Level and Physical Functioning

    Van Dyck, Delfien; Cardon, Greet; Deforche, Benedicte; De Bourdeaudhuij, Ilse

    2015-01-01

    Background The transition to retirement introduces a decline in total physical activity and an increase in TV viewing time. Nonetheless, as more time becomes available, early retirement is an ideal stage to implement health interventions. Therefore, knowledge on specific determinants of physical activity and sedentary time is needed. Former work-related physical activity has been proposed as a potential determinant, but concrete evidence is lacking. The aim of this study was to examine if former work-related sitting, standing, walking or vigorous activities predict physical activity and sedentary time during early retirement. Additionally, moderating effects of educational level and physical functioning were examined. Methods In total, 392 recently retired Belgian adults (>6 months, <5 years) completed the International Physical Activity Questionnaire, the SF-36 Health Survey and a questionnaire on sociodemographics and former work-related activities. Generalized linear regression analyses were conducted in R. Moderating effects were examined by adding cross-products to the models. Results More former work-related sitting was predictive of more screen time during retirement. Lower levels of former work-related vigorous activities and higher levels of former work-related walking were associated with respectively more cycling for transport and more walking for transport during retirement. None of the predictors significantly explained passive transportation, cycling and walking for recreation, and leisure-time moderate-to-vigorous physical activity during retirement. Several moderating effects were found, but the direction of the interactions was not univocal. Conclusions Former-work related behaviors are of limited importance to explain physical activity during early retirement, so future studies should focus on other individual, social and environmental determinants. Nonetheless, adults who previously had a sedentary job had higher levels of screen time during

  2. Cardiorespiratory fitness is a stronger indicator of cardiometabolic risk factors and risk prediction than self-reported physical activity levels.

    Gray, Benjamin J; Stephens, Jeffrey W; Williams, Sally P; Davies, Christine A; Turner, Daniel; Bracken, Richard M

    2015-11-01

    This study investigated the relationships of self-reported physical activity levels and cardiorespiratory fitness in 81 males to assess which measurement is the greatest indicator of cardiometabolic risk. Physical activity levels were determined by the General Practice Physical Activity Questionnaire tool and cardiorespiratory fitness assessed using the Chester Step Test. Cardiovascular disease risk was estimated using the QRISK2, Framingham Lipids, Framingham body mass index and Joint British Societies' Guidelines-2 equations, and type 2 diabetes mellitus risk calculated using QDiabetes, Leicester Risk Assessment, Finnish Diabetes Risk Score and Cambridge Risk Score models. Categorising employees by cardiorespiratory fitness categories ('Excellent/Good' vs 'Average/Below Average') identified more differences in cardiometabolic risk factor (body mass index, waist circumference, total cholesterol, total cholesterol:high-density lipoprotein ratio, high-density lipoprotein cholesterol, triglycerides, HbA(1c)) scores than physical activity (waist circumference only). Cardiorespiratory fitness levels also demonstrated differences in all four type 2 diabetes mellitus risk prediction models and both the QRISK2 and Joint British Societies' Guidelines-2 cardiovascular disease equations. Furthermore, significant negative correlations (p < 0.001) were observed between individual cardiorespiratory fitness values and estimated risk in all prediction models. In conclusion, from this preliminary observational study, cardiorespiratory fitness levels reveal a greater number of associations with markers of cardiovascular disease or type 2 diabetes mellitus compared to physical activity determined by the General Practice Physical Activity Questionnaire tool. PMID:26361778

  3. Body condition loss and increased serum levels of nonesterified fatty acids enhance progesterone levels at estrus and reduce estrous activity and insemination rates in postpartum dairy cows.

    Lüttgenau, J; Purschke, S; Tsousis, G; Bruckmaier, R M; Bollwein, H

    2016-03-01

    Data from 96 Holstein Friesian cows on a commercial dairy farm were used to investigate whether body condition and serum levels of nonesterified fatty acids (NEFAs) postpartum (pp) affect progesterone (P4) levels, estrous activity, and fertility in dairy cows. The examination period started 14 days before the expected calving date and ended either when a cow was inseminated or at a maximum of 90 days pp. Body condition score (BCS; 1-5 scale) and backfat thickness (BFT) were determined every 2 weeks. Blood for analysis of NEFA and P4 concentrations was sampled weekly during the first 35 days pp and then every 48 hours until an ovulation was observed. Transrectal ultrasonography of the ovaries started at 21 days pp and was performed after blood sampling. If cows were not inseminated because of silent ovulation, sampling and ultrasonography continued on Days 7, 14, and 18 after ovulation and again every 48 hours until the next ovulation. Estrous activity was continuously measured with the Heatime estrus detection system. Pregnancy controls were performed ultrasonographically 28 and 42 days after AI. Cows with increased NEFA levels at 28 days pp had an increased risk of maintaining minimum P4 levels above 0.4 ng/mL at first recognized estrus (P = 0.03). Higher NEFA levels at Day 7 were associated with lower probability for a cow to have elevated P4 levels (≥2 ng/mL) by Day 35 pp, indicating delayed commencement of luteal activity (C-LA). Estrous activity was not influenced (P > 0.10) by minimum P4 concentrations at estrus, but more animals with C-LA until Day 35 pp showed estrous activity compared to cows without C-LA throughout this period (P = 0.006). Estrous activity was lower in cows with a low BCS 14 days pp (P = 0.02) and with a low BFT 42 days pp (P = 0.03). Moreover, the probability to exhibit estrus was reduced with higher NEFA levels at 21 days pp (P = 0.01). Eighty-five cows were inseminated and 37 (44%) got pregnant after insemination. Higher NEFA levels

  4. Atmospheric Cerenkov light from large air showers observed at 5200m above sea level

    A preliminary result is presented on the arrival-time distribution of atmospheric Cerenkov light from air showers of 1017 eV observed at Chacaltaya. The rise time and the FWHM are consistent with those expected from high multiplicity models, indicating the very fast development of electrons at the early stage

  5. Earth observation space programmes, SAFISY activities, strategies of international organisations, legal aspects. Volume 3

    This volume is separated in four sessions. First part is on earth observation space programmes (international earth observation projects and international collaboration, the ERS-1, SPOT and PRIRODA programmes, the first ESA earth observation polar platform and its payload, the future earth observation remote sensing techniques and concepts). The second part is on SAFISY activities (ISY programmes, education and applications, demonstrations and outreach projects). The third part is on programme and strategies of international organisations with respect to earth observation from space. The fourth part is on legal aspects of the use of satellite remote sensing data in Europe. (A.B.). refs., figs., tabs

  6. Irisin Levels are Not Affected by Physical Activity in Patients with Anorexia Nervosa.

    Hofmann, Tobias; Elbelt, Ulf; Ahnis, Anne; Kobelt, Peter; Rose, Matthias; Stengel, Andreas

    2014-01-01

    Irisin was recently identified as muscle-derived hormone that increases energy expenditure. Studies in normal weight and obese subjects reported an increased irisin expression following physical activity, although inconsistent results were observed. Increased physical activity in a subgroup of patients with anorexia nervosa (AN) complicates the course of the disease. Since irisin could account for differences in clinical outcomes, we investigated irisin levels in anorexic patients with high and moderate physical activity to evaluate whether irisin differs with increasing physical activity. Hospitalized female anorexic patients (n = 39) were included. Plasma irisin measured by enzyme-linked immunosorbent assay and locomotor activity were assessed at the same time. Patients were separated into two groups (n = 19/group; median excluded): moderate and high activity (6331 ± 423 vs. 13743 ± 1047 steps/day, p  0.05), whereas body weight-adjusted total energy expenditure (46.0 ± 1.4 vs. 41.1 ± 1.1 kcal/kg/day), metabolic equivalents (METs, 1.9 ± 0.1 vs. 1.7 ± 0.1 METs/day), body weight-adjusted exercise activity thermogenesis (1.8 ± 0.5 vs. 0.6 ± 0.3 kcal/kg/day), duration of exercise (18.6 ± 4.7 vs. 6.2 ± 3.1 min/day), and body weight-adjusted non-exercise activity thermogenesis (21.6 ± 1.0 vs. 18.8 ± 0.8 kcal/kg/day) were higher in the high activity compared to the moderate activity group (p activity parameters in the whole sample (p > 0.05). In conclusion, the current data do not support the concept of irisin being induced by exercise, at least not under conditions of severely reduced body weight like AN. PMID:24432013

  7. Sea-level trend in the South China Sea observed from 20 years of along-track satellite altimetric data

    Cheng, Yongcun; Xu, Qing; Andersen, Ole Baltazar

    2014-01-01

    The sea-level trend in the South China Sea (SCS) is investigated based on 20 years of along-track data from TOPEX and Jason-1/2 satellite altimetry. The average sea-level rise over all the regions in the study area is observed to have a rate of 5.1 ± 0.8 mm year-1 for the period from 1993 to 2012...

  8. Geoethics: IPCC disgraced by violation of observational facts and physical laws in their sea level scenario

    Mörner, Nils-Axel

    2014-05-01

    Sea level may rise due to glacier melting, heat expansion of the oceanic water column, and redistribution of the waster masses - all these factors can be handled as to rates and amplitudes (provided one knows what one is talking about). In key areas over the entire Indian Ocean and in many Pacific Islands there are no traces of and sea level rise over the last 40-50 years. This is also the case for test-areas like Venice and the North Sea coasts. In the Kattegatt Sea one can fix the sea level factor to a maximum rise of 1.0-0.9 mm/year over the last century. The 204 tide gauges selected by NOAA for their global sea level monitoring provide a strong and sharp maximum (of 182 sites) in the range of 0.0-2.0 mm/yr. Satellite altimetry is said to give a rise of 3.2 mm/yr; this, however, is a value achieved after a quite subjective and surely erroneous "correction". The IPCC is talking about exceptionally much higher rates, and even worse are some "boy scouts" desperate try to launce real horror ratios. Physical laws set the frames of the rate and amount of ice melting, and so do records of events in the past (i.e. the geological records). During the Last Ice Age so much ice was accumulated on land, that the sea level dropped by about 120 m. When the process was reversed and ice melted under exceptionally strong climate forcing, sea level rose at a maximum rate of about 10 mm/yr (a meter per century). This can never happen under today's climate conditions. Even with IPCC's hypothetical scenarios, the true sea rise must be far less. When people like Rahmstorf (claiming 1 m or more by 2100) and Hansen (claiming a 4 m rise from 2080 to 2100) give their values, they exceed what is possible according to physical laws and accumulated geological knowledge. The expansion of the oceanic water column may reach amounts of sea level rise in the order of a few centimetres, at the most a decimetre. Old temperature measurements may record a temperature rise over the last 50 years in

  9. BEACHES: an observational system for assessing children's eating and physical activity behaviors and associated events.

    McKenzie, T L; Sallis, J F; Nader, P R; Patterson, T L; Elder, J. P.; Berry, C.C.; Rupp, J W; Atkins, C J; Buono, M J; Nelson, J A

    1991-01-01

    An integrated system for coding direct observations of children's dietary and physical activity behaviors was developed. Associated environmental events were also coded, including physical location, antecedents, and consequences. To assess the instrument's reliability and validity, 42 children, aged 4 to 8 years, were observed for 8 consecutive weeks at home and at school. Results indicated that four 60-min observations at home produced relatively stable estimates for most of the 10 dimension...

  10. Periodic Properties and Inquiry: Student Mental Models Observed during a Periodic Table Puzzle Activity

    Larson, Kathleen G.; Long, George R.; Briggs, Michael W.

    2012-01-01

    The mental models of both novice and advanced chemistry students were observed while the students performed a periodic table activity. The mental model framework seems to be an effective way of analyzing student behavior during learning activities. The analysis suggests that students do not recognize periodic trends through the examination of…

  11. Empathy levels among first year Malaysian medical students: an observational study

    Gopakumar A; Sreedharan J; Premadasa G; Muttappallymyalil J

    2014-01-01

    Brett Williams,1 Sivalal Sadasivan,2 Amudha Kadirvelu,2 Alexander Olaussen11Department of Community Emergency Health and Paramedic Practice, Melbourne, Australia; 2Jeffrey Cheah School of Medicine and Health Sciences, Sunway Campus, Selangor, MalaysiaBackground: The literature indicates that medical practitioners experience declining empathy levels in clinical practice. This highlights the need to educate medical students about empathy as an attribute early in the academic curriculum. The obj...

  12. Energy spectrum of cosmic-ray photons observed at the ground level in Japan

    The energy spectrum of cosmic-ray photons was estimated from the pulse-height spectra of cosmic-rays observed by a spherical NaI(Tl) scintillation detector. The pulse-height spectrum of cosmic-ray photons could be successfully separated on the basis of the difference between the pulse-height spectrum by a spherical NaI(Tl) scintillation detector and that by coincidence counting method. It seemed that the pulse-height spectra of cosmic-ray muons by the each measuring system resemble each other in shape, while the pulse-height spectra of cosmic-ray electrons by the each system different each other. So the pulse-height distribution of cosmic-ray muons was determined from the pulse-height spectrum observed by the detector covered with lead. The pulse-height distribution of cosmic-ray electrons was determined as follows: The shape of pulse-height spectrum was calculated on the basis of the energy spectra of cosmic-ray electrons in the lower atmosphere. The pulse-height distributions of cosmic-ray electrons by the single detector system and by the coincidence detector system were calculated by using the EGS4 Monte Carlo Code. The intensity of cosmic-ray electrons was determined by subtracting the pulse-height spectrum observed by the detector covered with lead from that observed by the coincidence detector system. The pulse-height distribution of cosmic-ray photons could be determined from the pulse-height spectrum by the coincidence detector system subtracted from that by the single detector system. The energy spectrum of cosmic-ray photons could be calculated from the pulse-height distribution of cosmic-ray photons by using an unfolding method. It became clear that the energy spectrum of cosmic-ray photons was identified above scores of MeV. (author)

  13. Energetic delayed hadrons in large air showers observed at 5200m above sea level

    Kaneko, T.; Hagiwara, K.; Yoshii, H.; Martinic, N.; Siles, L.; Miranda, P.; Kakimoto, F.; Tsuchimoto, I.; Inoue, N.; Suga, K.

    1985-01-01

    Energetic delayed hadrons in air showers with electron sizes in the range 10 to the 6th power to 10 to the 9th power were studied by observing the delayed bursts produced in the shield of nine square meter scintillation detectors in the Chacaltaya air-shower array. The frequency of such delayed burst is presented as a function of electron size, core distance and sec theta.

  14. Direct observation of population transfer between the upper laser levels in a copper vapor laser

    The copper vapor laser (CVL) produces output at two wavelengths, 511 and 578 nm. These lines do not have common upper or lower levels. It would be extremely desirable to be able to extract the population of both upper levels on one transition only. Whether this is feasible depends critically on the extent to which the population can be transferred between them during a laser pulse. There are several mechanisms which might cause such population transfer: copper-copper, copper-buffer gas, and coper-electron collisions. In normal lasing conditions, calculations indicate that copper-buffer gas collisions should dominate over copper-copper collisions. There are insufficient data to predict whether copper-electron collisions are competitive. The authors have performed a series of experiments in a 10-W CVL (25-mm i.d., 700 mm long) to study the population transfer mechanisms in optimum lasing conditions. They conclude that, although population transfer between the upper levels of a CVL occurs, it does not play an important role in CVL kinetics

  15. Human movements and abstract motion displays activate different processes in the observer's motor system.

    Agosta, Sara; Battelli, Lorella; Casile, Antonino

    2016-04-15

    Brain imaging studies have shown that observation of both bodily movements and abstract motion displays complying with human kinematics activate the observer's motor cortex. However, it is unknown whether the same processes are active in the two conditions. Here, we addressed this issue using transcranial magnetic stimulation (TMS) to directly compare cortico-spinal excitability during observation of actions and motion stimuli that complied with or violated normal human kinematics. We found that kinematics significantly modulated the motor-evoked potentials (MEPs) produced by TMS during observation of both human and abstract motion stimuli. However, only the temporal unfolding of cortico-spinal excitability during observation of human movements significantly correlated with instantaneous stimulus velocity. This correlation was present for normal movements and also for a subset of the movements having unnatural kinematics. Furthermore, bodily movements for which we found no correlation between MEPs and stimulus velocity produced significantly higher MEPs. Our novel results suggest a dissociation in how human movements and abstract motion displays engage the observer's motor system. Specifically, while both stimulus types significantly activate the observer's motor cortex, only bodily movements produce patterns of cortico-spinal excitability that closely follow the velocity profile of the observed movement. This internal "re-enactment" of observed bodily movements seems to be only partially attuned to normal human kinematics. PMID:26854559

  16. Is Brain Activity during Action Observation Modulated by the Perceived Fairness of the Actor?

    Joset A Etzel

    Full Text Available Perceiving other people's actions triggers activity in premotor and parietal areas, brain areas also involved in executing and sensing our own actions. Paralleling this phenomenon, observing emotional states (including pain in others is associated with activity in the same brain areas as activated when experiencing similar emotions directly. This emotion perception associated activity has been shown to be affected by the perceived fairness of the actor, and in-group membership more generally. Here, we examine whether action observation associated brain activity is also affected by the perceived social fairness of the actors. Perceived fairness was manipulated using an alternating iterated Prisoner's Dilemma game between the participant and two confederates, one of whom played fairly and the other unfairly. During fMRI scanning the participants watched movies of the confederates performing object-directed hand actions, and then performed hand actions themselves. Mass-univariate analysis showed that observing the actions triggered robust activation in regions associated with action execution, but failed to identify a strong modulation of this activation based on perceived fairness. Multivariate pattern analysis, however, identified clusters potentially carrying information about the perceived fairness of the actor in the middle temporal gyrus, left postcentral gyrus, right inferior parietal lobule, right middle cingulate cortex, right angular gyrus, and right superioroccipital gyrus. Despite being identified by a whole-brain searchlight analysis (and so without anatomical restriction, these clusters fall into areas frequently associated with action observation. We conclude that brain activity during action observation may be modulated by perceived fairness, but such modulation is subtle; robust activity is associated with observing the actions of both fair and unfair individuals.

  17. Is Brain Activity during Action Observation Modulated by the Perceived Fairness of the Actor?

    Etzel, Joset A; Valchev, Nikola; Gazzola, Valeria; Keysers, Christian

    2016-01-01

    Perceiving other people's actions triggers activity in premotor and parietal areas, brain areas also involved in executing and sensing our own actions. Paralleling this phenomenon, observing emotional states (including pain) in others is associated with activity in the same brain areas as activated when experiencing similar emotions directly. This emotion perception associated activity has been shown to be affected by the perceived fairness of the actor, and in-group membership more generally. Here, we examine whether action observation associated brain activity is also affected by the perceived social fairness of the actors. Perceived fairness was manipulated using an alternating iterated Prisoner's Dilemma game between the participant and two confederates, one of whom played fairly and the other unfairly. During fMRI scanning the participants watched movies of the confederates performing object-directed hand actions, and then performed hand actions themselves. Mass-univariate analysis showed that observing the actions triggered robust activation in regions associated with action execution, but failed to identify a strong modulation of this activation based on perceived fairness. Multivariate pattern analysis, however, identified clusters potentially carrying information about the perceived fairness of the actor in the middle temporal gyrus, left postcentral gyrus, right inferior parietal lobule, right middle cingulate cortex, right angular gyrus, and right superioroccipital gyrus. Despite being identified by a whole-brain searchlight analysis (and so without anatomical restriction), these clusters fall into areas frequently associated with action observation. We conclude that brain activity during action observation may be modulated by perceived fairness, but such modulation is subtle; robust activity is associated with observing the actions of both fair and unfair individuals. PMID:26820995

  18. Low-level laser therapy activates NF-kB via generation of reactive oxygen species in mouse embryonic fibroblasts.

    Aaron C-H Chen

    Full Text Available BACKGROUND: Despite over forty years of investigation on low-level light therapy (LLLT, the fundamental mechanisms underlying photobiomodulation at a cellular level remain unclear. METHODOLOGY/PRINCIPAL FINDINGS: In this study, we isolated murine embryonic fibroblasts (MEF from transgenic NF-kB luciferase reporter mice and studied their response to 810 nm laser radiation. Significant activation of NF-kB was observed at fluences higher than 0.003 J/cm(2 and was confirmed by Western blot analysis. NF-kB was activated earlier (1 hour by LLLT compared to conventional lipopolysaccharide treatment. We also observed that LLLT induced intracellular reactive oxygen species (ROS production similar to mitochondrial inhibitors, such as antimycin A, rotenone and paraquat. Furthermore, we observed similar NF-kB activation with these mitochondrial inhibitors. These results, together with inhibition of laser induced NF-kB activation by antioxidants, suggests that ROS play an important role in the laser induced NF-kB signaling pathways. However, LLLT, unlike mitochondrial inhibitors, induced increased cellular ATP levels, which indicates that LLLT also upregulates mitochondrial respiration. CONCLUSION: We conclude that LLLT not only enhances mitochondrial respiration, but also activates the redox-sensitive NFkB signaling via generation of ROS. Expression of anti-apoptosis and pro-survival genes responsive to NFkB could explain many clinical effects of LLLT.

  19. Low-Level Laser Therapy Activates NF-kB via Generation of Reactive Oxygen Species in Mouse Embryonic Fibroblasts

    Huang, Ying-Ying; Tomkinson, Elizabeth M.; Sharma, Sulbha K.; Kharkwal, Gitika B.; Saleem, Taimur; Mooney, David; Yull, Fiona E.; Blackwell, Timothy S.; Hamblin, Michael R.

    2011-01-01

    Background Despite over forty years of investigation on low-level light therapy (LLLT), the fundamental mechanisms underlying photobiomodulation at a cellular level remain unclear. Methodology/Principal Findings In this study, we isolated murine embryonic fibroblasts (MEF) from transgenic NF-kB luciferase reporter mice and studied their response to 810 nm laser radiation. Significant activation of NF-kB was observed at fluences higher than 0.003 J/cm2 and was confirmed by Western blot analysis. NF-kB was activated earlier (1 hour) by LLLT compared to conventional lipopolysaccharide treatment. We also observed that LLLT induced intracellular reactive oxygen species (ROS) production similar to mitochondrial inhibitors, such as antimycin A, rotenone and paraquat. Furthermore, we observed similar NF-kB activation with these mitochondrial inhibitors. These results, together with inhibition of laser induced NF-kB activation by antioxidants, suggests that ROS play an important role in the laser induced NF-kB signaling pathways. However, LLLT, unlike mitochondrial inhibitors, induced increased cellular ATP levels, which indicates that LLLT also upregulates mitochondrial respiration. Conclusion We conclude that LLLT not only enhances mitochondrial respiration, but also activates the redox-sensitive NFkB signaling via generation of ROS. Expression of anti-apoptosis and pro-survival genes responsive to NFkB could explain many clinical effects of LLLT. PMID:21814580

  20. Interevent time distributions of human multi-level activity in a virtual world

    Mryglod, O.; Fuchs, B.; Szell, M.; Holovatch, Yu.; Thurner, S.

    2015-02-01

    Studying human behavior in virtual environments provides extraordinary opportunities for a quantitative analysis of social phenomena with levels of accuracy that approach those of the natural sciences. In this paper we use records of player activities in the massive multiplayer online game Pardus over 1238 consecutive days, and analyze dynamical features of sequences of actions of players. We build on previous work where temporal structures of human actions of the same type were quantified, and provide an empirical understanding of human actions of different types. This study of multi-level human activity can be seen as a dynamic counterpart of static multiplex network analysis. We show that the interevent time distributions of actions in the Pardus universe follow highly non-trivial distribution functions, from which we extract action-type specific characteristic 'decay constants'. We discuss characteristic features of interevent time distributions, including periodic patterns on different time scales, bursty dynamics, and various functional forms on different time scales. We comment on gender differences of players in emotional actions, and find that while males and females act similarly when performing some positive actions, females are slightly faster for negative actions. We also observe effects on the age of players: more experienced players are generally faster in making decisions about engaging in and terminating enmity and friendship, respectively.

  1. Recruitment of rat diaphragm motor units across motor behaviors with different levels of diaphragm activation.

    Seven, Yasin B; Mantilla, Carlos B; Sieck, Gary C

    2014-12-01

    Phrenic motor neurons are recruited across a range of motor behaviors to generate varying levels of diaphragm muscle (DIAm) force. We hypothesized that DIAm motor units are recruited in a fixed order across a range of motor behaviors of varying force levels, consistent with the Henneman Size Principle. Single motor unit action potentials and compound DIAm EMG activities were recorded in anesthetized, neurally intact rats across different motor behaviors, i.e., eupnea, hypoxia-hypercapnia (10% O2 and 5% CO2), deep breaths, sustained airway occlusion, and sneezing. Central drive [estimated by root-mean-squared (RMS) EMG value 75 ms after the onset of EMG activity (RMS75)], recruitment delay, and onset discharge frequencies were similar during eupnea and hypoxia-hypercapnia. Compared with eupnea, central drive increased (∼25%) during deep breaths, and motor units were recruited ∼12 ms earlier (P hypoxia-hypercapnia, deep breaths, and airway occlusion, respectively. Reversals in motor unit recruitment order were observed primarily if motor unit pairs were recruited <20 ms apart. These results are consistent with DIAm motor unit recruitment order being determined primarily by the intrinsic size-dependent electrophysiological properties of phrenic motor neurons. PMID:25257864

  2. European Space Agency Campaign Activities in Support of Earth Observation Projects: Examples for Snow and Ice

    Schüttemeyer, D.; Davidson, M.; Casal, T.; Perrera, A.; Bianchi, R.; Kern, M.; Scipal, K.

    2012-04-01

    In the framework of its Earth Observation Programmes the European Space Agency (ESA) carries out groundbased and airborne campaigns to support geophysical algorithm development, calibration/validation, simulation of future spaceborne earth observation missions, and applications development related to land, oceans and atmosphere. Campaigns in support of future mission development have technological, geophysical and simulation objectives while exploitation projects need validation for the assessment of the quality of the earth observation products and of the service provision. ESA has been conducting airborne and ground measurements campaigns since 1981 by deploying a broad range of active and passive instrumentation in both the optical and microwave regions of the electromagnetic spectrum such as lidars, limb/nadir sounding interferometers/spectrometers, high-resolution spectral imagers, advanced synthetic aperture radars, altimeters and radiometers. These campaigns take place inside and outside Europe in collaboration with national research organisations in the ESA member states as well as with international organisations harmonising European campaign activities. For the different activities a rich variety of datasets has been recorded, are archived and users can access campaign data through the EOPI web portal [http://eopi.esa.int]. In 2005, ESA released a call for the next Earth Explorer Core Mission Ideas with the aim to select a 7th Earth Explorer (EE7) mission to be launched in the next decade. Twenty-four proposals were received and subject to detailed scientific and technical assessment. During the so-called Phase 0, six concepts were selected and further investigated. A down-selection was made after the User Consultation Meeting held in Lisbon, Portugal in January 2009. Three candidate mission concepts were selected for further feasibility phase (phase A) investigation. Each of the candidate missions are being elaborated through two parallel industrial

  3. Long-time water level observations at the HDR-testsite Soultz-sous-Forets

    Dornstaedter, J.; Heinemann-Glutsch, B.; Zaske, J. [GTC-Kappelmeyer GmbH, Karlsruhe (Germany)

    1997-12-01

    Pressure or water level measurements have been performed by GTC in different wells at the geothermal testsite Soultz-sous-Forets for six years now. The water lever variations are mainly influenced by earth tides, barometric pressure variations, hydraulic testing and stimulation. The small scale variations are influenced by tidal and barometric forcing functions, the large scale variations by hydraulic testing and stimulation. By analyzing such measurements it is possible to get important information about the hydrualic connections between the boreholes, as well as aquifer parameters. (orig./AKF)

  4. Detection and differentiation of contamination through a comparison of observed levels in historical environmental sampling data

    In summarizing more than a decade of environmental monitoring data from the Hanford Site, we noted that grouping data by analysis, rather than by medium, enhanced visual as well as statistical interpretations. By plotting running-averages of individual radionuclides on the same graph, for different media, we evaluated environmental trends to determine whether or not a local impact had been observed. This approach may enhance ones ability to interpret environmental monitoring data collected following an unplanned release of radionuclides. This technique provides a more holistic approach to the evaluation of environmental monitoring data than has traditionally been practiced

  5. Detection and differentiation of contamination through a comparison of observed levels in historical environmental sampling data

    In summarizing more than a decade of environmental monitoring data from the Hanford Site, we noted that grouping data by analysis, rather than by medium, enhanced visual as well as statistical interpretations. By plotting running-averages of individual radionuclides on the same graph, for different media, we evaluated environmental trends to determine whether or not a local impact had been observed. This approach may enhance ones ability to interpret environmental monitoring data collected following an unplanned release of radionuclides. This technique provides a more holistic approach to the evaluation of environmental monitoring data than has traditionally been practiced. (author)

  6. Influence of cardiorespiratory fitness and physical activity levels on cardiometabolic risk factors during menopause transition: A MONET study.

    Abdulnour, Joseph; Razmjou, Sahar; Doucet, Éric; Boulay, Pierre; Brochu, Martin; Rabasa-Lhoret, Rémi; Lavoie, Jean-Marc; Prud'homme, Denis

    2016-12-01

    To determine the influence of cardiorespiratory fitness (hereafter "fitness") and physical activity levels on cardiometabolic risk factors in premenopausal women going through the menopause transition. An ancillary study including 66 premenopausal women who participated to a 5-year observational, longitudinal study (2004 to 2009 in Ottawa) on the effects of menopause transition on body composition and cardiometabolic risk factors. Women underwent a graded exercise test on treadmill to measure peak oxygen uptake (VO2 peak) at year 1 and 5 and physical activity levels were measured using accelerometers. Cardiometabolic risk factors included: waist circumference, fasting plasma lipids, glucose and insulin levels, HOMA-IR score, c-reactive protein, apolipoprotein B (apoB) and resting systolic and diastolic blood pressure. Change in fitness was not associated with changes in cardiometabolic risk factors. The changes in total physical activity levels on the other hand showed a significant negative association with apoB levels. Three-way linear mixed model repeated measures, showed lower values of waist circumference, fasting triglycerides, insulin levels, HOMA-IR score, apoB and diastolic blood pressure in women with a fitness ≥ 30.0 mlO2 kg(- 1) min(- 1) compared to women with a fitness fitness and physical activity levels, fitness was associated with more favorable values of cardiometabolic risk factors in women followed for 5 years during the menopause transition. PMID:27453812

  7. Active Drumming Experience Increases Infants' Sensitivity to Audiovisual Synchrony during Observed Drumming Actions.

    Sarah A Gerson

    Full Text Available In the current study, we examined the role of active experience on sensitivity to multisensory synchrony in six-month-old infants in a musical context. In the first of two experiments, we trained infants to produce a novel multimodal effect (i.e., a drum beat and assessed the effects of this training, relative to no training, on their later perception of the synchrony between audio and visual presentation of the drumming action. In a second experiment, we then contrasted this active experience with the observation of drumming in order to test whether observation of the audiovisual effect was as effective for sensitivity to multimodal synchrony as active experience. Our results indicated that active experience provided a unique benefit above and beyond observational experience, providing insights on the embodied roots of (early music perception and cognition.

  8. Vitamin D Levels Are Associated with Cardiac Autonomic Activity in Healthy Humans

    Linda Ellis

    2013-06-01

    Full Text Available Vitamin D deficiency (≤50nmol/L 25-hydroxy vitamin D is a cardiovascular (CV risk factor that affects approximately one billion people worldwide, particularly those affected by chronic kidney disease (CKD. Individuals with CKD demonstrate abnormal cardiac autonomic nervous system activity, which has been linked to the significant rates of CV-related mortality in this population. Whether vitamin D deficiency has a direct association with regulation of cardiac autonomic activity has never been explored in humans. Methods: Thirty-four (34 healthy, normotensive subjects were studied and categorized based on 25-hydroxy vitamin D deficiency (deficient vs. non-deficient, n = 7 vs. 27, as well as 1,25-dihydroxy vitamin D levels (above vs. below 25th percentile, n = 8 vs. 26. Power spectral analysis of electrocardiogram recordings provided measures of cardiac autonomic activity across low frequency (LF and high frequency (HF, representative of vagal contribution bands, representative of the sympathetic and vagal limbs of the autonomic nervous system when transformed to normalized units (nu, respectively, as well as overall cardiosympathovagal balance (LF:HF during graded angiotensin II (AngII challenge (3 ng/kg/min × 30 min, 6 ng/kg/min × 30 min. Results: At baseline, significant suppression of sympathovagal balance was observed in the 25-hydroxy vitamin D-deficient participants (LF:HF, p = 0.02 vs. non-deficient, although no other differences were observed throughout AngII challenge. Participants in the lowest 1,25-dihydroxy VD quartile experienced significant withdrawal of inhibitory vagal control, as well as altered overall sympathovagal balance throughout AngII challenge (HF, mean difference = −6.98 ± 3 nu, p = 0.05; LF:HF, mean difference = 0.34 ± 0.1, p = 0.043 vs. above 25th percentile. Conclusions: Vitamin D deficiency is associated with suppression of resting cardiac autonomic activity, while low 1,25-dihydroxy vitamin D levels are

  9. Postpartum hemorrhage is related to the hemoglobin levels at labor: Observational study

    Kaima A. Frass

    2015-12-01

    Full Text Available Background: Anemia in pregnancy is common and linked to postpartum hemorrhage in terms of uterine atony. The more severe the anemia, the more likely the greater blood loss and adverse outcome. The aim of this study was to examine the association between anemic women at labor and postpartum hemorrhage (PPH during emergency cesarean delivery and to assess the hemoglobin (Hb values at which the emergency hysterectomy is needed. Methods and patients: A cross-sectional study was carried out between (Aug. 1st 2012 and Jul. 30th 2013 at Al Thawra General hospital. Fifty-three cases were included in the study. Results: Postpartum hemorrhage was developed in 53 women (29.1%. Out of 53 women, 21 cases (39.6% had severe uterine atony and required emergency hysterectomy and the remaining 32 cases (60.37% responded to the conservative measures (p 0.03. Most of the hysterectomized women 80.75% (17/21 had Hb levels ⩽ 7 versus 12.5% of the nonhysterectomized patients [OR 29.75; 95% CI 6.564–134.53; p < 0.01]. There was a strong correlation between low Hb levels and blood loss [r = −.619; p < 0.00]. Conclusion: Our study supports the association between anemia (Hb < 10 and the risk of PPH. We also provide evidence of the association between severe anemia and emergency hysterectomy.

  10. Field observations of wave-driven water-level gradients across a coral reef flat

    Jago, O. K.; Kench, P. S.; Brander, R. W.

    2007-06-01

    Field measurements of still water surface elevations were obtained across a narrow leeward reef flat on Lady Elliot Island, Great Barrier Reef, Australia in June 2003. Stilling wells were deployed from the reef crest landward to the island beach, and waves and mean water levels were monitored over both rising and falling tides during low to moderate wave energy conditions. Wave setup of up to 13.8 cm above still water level occurred in the presence of incident waves of 0.4 m yielding maximum water surface slopes greater than 6°. Results show that the magnitude of wave setup varies both temporally and spatially across the reef with changing water depth. Setup is dominant on the reef edge at low tide, evolving into a dual setup system at both the reef edge and shoreline at midtide and finally a dominant shoreline setup at high tide. On Lady Elliot Island the dual setup system is considered to result from spatial differences in transformation and breaking of swell and wind waves at midtide stages. The presence of a dual setup system across a reef flat has not been previously identified in field or modeling studies and has potentially significant implications for reefal current development, sediment transport, and the stability of reef island shorelines.

  11. Observation of gamma ray bursts at ground level under the thunderclouds

    Kuroda, Y.; Oguri, S.; Kato, Y.; Nakata, R.; Inoue, Y.; Ito, C.; Minowa, M.

    2016-07-01

    We observed three γ-ray bursts related to thunderclouds in winter using the prototype of anti-neutrino detector PANDA made of 360-kg plastic scintillator deployed at Ohi Power Station at the coastal area of the Japan Sea. The maximum rate of the events which deposited the energy higher than 3 MeV was (5.5 ± 0.1) ×102 /s. Monte Carlo simulation showed that electrons with approximately monochromatic energy falling downwards from altitudes of order 100 m roughly produced the observed total energy spectra of the bursts. It is supposed that secondary cosmic-ray electrons, which act as seed, were accelerated in electric field of thunderclouds and multiplied by relativistic runaway electron avalanche. We actually found that the γ-rays of the bursts entered into the detector from the direction close to the zenith. The direction stayed constant during the burst within the detector resolution. In addition, taking advantage of the delayed coincidence detection of the detector, we found neutron events in one of the bursts at the maximum rate of ∼ 14 ± 5 /s.

  12. Observation of gamma ray bursts at ground level under the thunderclouds

    Kuroda, Y; Kato, Y; Nakata, R; Inoue, Y; Ito, C; Minowa, M

    2016-01-01

    We observed three $\\gamma$-ray bursts related to thunderclouds in winter using the prototype of anti-neutrino detector PANDA made of 360-kg plastic scintillator deployed at Ohi Power Station at the coastal area of the Japan Sea. The maximum rate of the events which deposited the energy higher than 3 MeV was $(5.5 \\pm 0.1) \\times 10^2 {\\rm /s}$. Monte Carlo simulation showed that the observed total energy spectra of the bursts are well described by the bremsstrahlung $\\gamma$-rays by electrons with approximately monochromatic energy falling downwards from altitudes of order $100\\,$m. It is supposed that secondary cosmic-ray electrons, which act as seed, were accelerated in electric field of thunderclouds and multiplied by relativistic runaway electron avalanche. We actually found that the $\\gamma$-rays of the bursts entered into the detector from the direction close to the zenith. The direction stayed constant during the burst within the detector resolution. In addition, taking advantage of the delayed coincid...

  13. Observations and Modeling of Low Level Moisture Convergence Patterns in the Southern Appalachians during the Integrated Precipitation and Hydrology Experiment (IPHEx) Extended Observing Period

    Wilson, Anna M.; Barros, Ana P.

    2015-04-01

    Accurate fields of precipitation accumulations and intensity at high spatial resolution in regions of complex terrain are largely unavailable. This is due to first, a lack of existing in situ observations, both because of the challenge in having high enough density in the instrument placement to represent the large spatial heterogeneity in rainfall patterns in these regions and because of the remote, harsh nature of the terrain that makes it difficult to install and maintain instrumentation and second, obstacles to remote sensing such as beam blockage and ground clutter that are caused by the complex orography. In this study we leverage observations from two sources: 1) a high-elevation, high-density tipping bucket rain gauge network that has been recording precipitation observations for over six years along ridgelines in the Pigeon River Basin, a small watershed in the Southern Appalachians, and 2) the 4-D database of observations collected in 2014 in support of the Global Precipitation Mission (GPM) during the first field campaign after the launch of the GPM satellite, the Integrated Precipitation and Hydrology Experiment (IPHEx), to learn about formation and maintenance mechanisms for fog and low cloud in this region and the resulting impact on the precipitation regime. The observations focused on here are those at the near surface, within 2 kilometers of the ground level. This presentation will focus on process-based modeling studies using the Advanced Research Weather and Forecasting Model conducted based upon observations made during this campaign. Case studies will be presented for real events simulated during the IPHEx campaign. These case studies occurred with different synoptic conditions, but include observational evidence of orographic enhancement. The case studies are simulated and analyzed in order to investigate how the topography modulates the regional, diurnal patterns of moisture convergence and fog and low cloud formation, as well as the mid

  14. Enhanced activation of motor execution networks using action observation combined with imagination of lower limb movements.

    Villiger, Michael; Estévez, Natalia; Hepp-Reymond, Marie-Claude; Kiper, Daniel; Kollias, Spyros S; Eng, Kynan; Hotz-Boendermaker, Sabina

    2013-01-01

    The combination of first-person observation and motor imagery, i.e. first-person observation of limbs with online motor imagination, is commonly used in interactive 3D computer gaming and in some movie scenes. These scenarios are designed to induce a cognitive process in which a subject imagines himself/herself acting as the agent in the displayed movement situation. Despite the ubiquity of this type of interaction and its therapeutic potential, its relationship to passive observation and imitation during observation has not been directly studied using an interactive paradigm. In the present study we show activation resulting from observation, coupled with online imagination and with online imitation of a goal-directed lower limb movement using functional MRI (fMRI) in a mixed block/event-related design. Healthy volunteers viewed a video (first-person perspective) of a foot kicking a ball. They were instructed to observe-only the action (O), observe and simultaneously imagine performing the action (O-MI), or imitate the action (O-IMIT). We found that when O-MI was compared to O, activation was enhanced in the ventralpremotor cortex bilaterally, left inferior parietal lobule and left insula. The O-MI and O-IMIT conditions shared many activation foci in motor relevant areas as confirmed by conjunction analysis. These results show that (i) combining observation with motor imagery (O-MI) enhances activation compared to observation-only (O) in the relevant foot motor network and in regions responsible for attention, for control of goal-directed movements and for the awareness of causing an action, and (ii) it is possible to extensively activate the motor execution network using O-MI, even in the absence of overt movement. Our results may have implications for the development of novel virtual reality interactions for neurorehabilitation interventions and other applications involving training of motor tasks. PMID:24015241

  15. Enhanced activation of motor execution networks using action observation combined with imagination of lower limb movements.

    Michael Villiger

    Full Text Available The combination of first-person observation and motor imagery, i.e. first-person observation of limbs with online motor imagination, is commonly used in interactive 3D computer gaming and in some movie scenes. These scenarios are designed to induce a cognitive process in which a subject imagines himself/herself acting as the agent in the displayed movement situation. Despite the ubiquity of this type of interaction and its therapeutic potential, its relationship to passive observation and imitation during observation has not been directly studied using an interactive paradigm. In the present study we show activation resulting from observation, coupled with online imagination and with online imitation of a goal-directed lower limb movement using functional MRI (fMRI in a mixed block/event-related design. Healthy volunteers viewed a video (first-person perspective of a foot kicking a ball. They were instructed to observe-only the action (O, observe and simultaneously imagine performing the action (O-MI, or imitate the action (O-IMIT. We found that when O-MI was compared to O, activation was enhanced in the ventralpremotor cortex bilaterally, left inferior parietal lobule and left insula. The O-MI and O-IMIT conditions shared many activation foci in motor relevant areas as confirmed by conjunction analysis. These results show that (i combining observation with motor imagery (O-MI enhances activation compared to observation-only (O in the relevant foot motor network and in regions responsible for attention, for control of goal-directed movements and for the awareness of causing an action, and (ii it is possible to extensively activate the motor execution network using O-MI, even in the absence of overt movement. Our results may have implications for the development of novel virtual reality interactions for neurorehabilitation interventions and other applications involving training of motor tasks.

  16. Relationships among Physical Activity Levels, Psychomotor, Psychosocial, and Cognitive Development of Primary Education Students.

    Isler, Ayse Kin; Asci, F. Hulya; Kosar, S. Nazan

    2002-01-01

    Investigated the relationships of physical activity levels and psychomotor, psychosocial, and cognitive development among Turkish elementary school students. Student evaluations indicated that physical activity level was an important factor in determining student psychomotor development, but it was not important in determining psychosocial and…

  17. Determination of activation level energy of nuclear isomers by calibration of microspectra of radioactive sources

    Nuclear isomers with unknown activation level were irradiated by calibrated radioactive sources. The integral cross sections were calculated for different energies of the sources. The activation energy was given by values coinciding with each other within the limits of error. The method made the determination of the unknown level of 1180+-10 keV of 195Pt nucleus possible. (author)

  18. Level and determinants of physical activity among school adolescents in Poland

    Barbara Bergier

    2014-03-01

    Full Text Available The recognition of adolescents’ physical activity has become one of the serious challenges of the modern times, as a concern about the future health of societies. The major goal of the presented study was to discover the level of physical activity among Polish adolescents aged 16–18, and the factors which condition this level. The investigations were carried out in 2011, among 2,974 school adolescents from various locations in Poland – 1,790 girls (60.2%, and 1,184 boys (39.8%. As a study method, a short version of the IPAQ was applied. The results of the study indicated that a larger number of girls than boys show a low level of physical activity. With respect to activity among boys, higher values of intensive and moderate efforts are noted, while in girls, higher values of activities related to walking. It was confirmed that the level of physical activity does not depend on the place of residence. However, the number of physical exercise classes attended is a significant factor, both among boys and girls. It was also found that adolescents who more frequently lead a sedentary style of life are characterized by a lower level of total physical activity. Sedentary lifestyle (time spent sitting does not differ among the level of physical activity of girls and of boys, neither with respect to the scope of the total physical activity nor to its three levels (low, moderate, high.

  19. TEMPERATURE DISTRIBUTION OF A NON-FLARING ACTIVE REGION FROM SIMULTANEOUS HINODE XRT AND EIS OBSERVATIONS

    We analyze coordinated Hinode X-ray Telescope (XRT) and Extreme Ultraviolet Imaging Spectrometer (EIS) observations of a non-flaring active region to investigate the thermal properties of coronal plasma taking advantage of the complementary diagnostics provided by the two instruments. In particular, we want to explore the presence of hot plasma in non-flaring regions. Independent temperature analyses from the XRT multi-filter data set, and the EIS spectra, including the instrument entire wavelength range, provide a cross-check of the different temperature diagnostics techniques applicable to broadband and spectral data, respectively, and insights into cross-calibration of the two instruments. The emission measure distributions, (EM(T)), we derive from the two data sets have similar width and peak temperature, but show a systematic shift of the absolute values, the EIS (EM(T)) being smaller than the XRT (EM(T)) by approximately a factor two. We explore possible causes of this discrepancy, and we discuss the influence of the assumptions for the plasma element abundances. Specifically, we find that the disagreement between the results from the two instruments is significantly mitigated by assuming chemical composition closer to the solar photospheric composition rather than the often adopted 'coronal' composition. We find that the data do not provide conclusive evidence on the high temperature (log T(K) ∼> 6.5) tail of the plasma temperature distribution, however, suggesting its presence to a level in agreement with recent findings for other non-flaring regions.

  20. Observations of total electron content perturbations on GPS signals caused by a ground level explosion

    Fitzgerald, T. Joseph

    1997-05-01

    We have measured perturbations of electron density in the ionosphere caused by a ground level explosion with an energy release of 2 kt (8.5 × 1012 J) using transmissions from Global Positioning System (GPS) satellites to monitor integrated electron density. The frequencies of the transmissions were 1575.42 MHz (L1) and 1227.60 MHz (L2). The detected perturbation showed a maximum excursion of 0.14 TEC units and had a duration of 80 s beginning at 565 s after the explosion. The acoustic disturbance necessary to produce such a perturbation is well modeled as an N wave with a dimension of 35 km and a relative amplitude of 12% propagating radially at a speed of 0.7 km/s. The majority of the TEC perturbation occurred at an altitude of approximately 200 km.

  1. The observation of leptin levels in pregnant women newborn and newborn's weight and its clinical significance

    To study the relationship of leptin quantity of placenta, amniotic fluid, umbilical blood, maternal blood and newborn's weight, leptin levels of placenta, amniotic fluid, umbilical blood and maternal blood of 59 pregnant women were detected by RIA. Results were: (1) leptin was be detected from placenta, amniotic fluid, umbilical blood and maternal blood; (2) there was an obvious difference between leptin quantities of placenta, amniotic fluid, umbilical blood and maternal blood (P < 0.01); (3) there was an obvious difference between leptin quantities of placenta, amniotic fluid, umbilical blood and maternal blood for normal pregnant women and pregnancy induced hypertension (P < 0.01); (4) there was an obvious difference between leptin quantities of maternal blood and placenta (P < 0.01). It may be of important significance to detect eh leptin quantity of amniotic fluid and maternal blood in pregnant women for predicting the weight and growth of newborns and treat pregnancy induced hypertension

  2. Increased premotor cortex activation in high functioning autism during action observation.

    Perkins, Tom J; Bittar, Richard G; McGillivray, Jane A; Cox, Ivanna I; Stokes, Mark A

    2015-04-01

    The mirror neuron (MN) hypothesis of autism has received considerable attention, but to date has produced inconsistent findings. Using functional MRI, participants with high functioning autism or Asperger's syndrome were compared to typically developing individuals (n=12 in each group). Participants passively observed hand gestures that included waving, pointing, and grasping. Concerning the MN network, both groups activated similar regions including prefrontal, inferior parietal and superior temporal regions, with the autism group demonstrating significantly greater activation in the dorsal premotor cortex. Concerning other regions, participants with autism demonstrated increased activity in the anterior cingulate and medial frontal gyrus, and reduced activation in calcarine, cuneus, and middle temporal gyrus. These results suggest that during observation of hand gestures, frontal cortex activation is affected in autism, which we suggest may be linked to abnormal functioning of the MN system. PMID:25726458

  3. Long term flaring activity of XRF 011030 observed with BeppoSAX

    A. Galli; Piro, L.

    2005-01-01

    We present the spectral and temporal analysis of the X-ray flash XRF011030 observed with BeppoSAX. This event is characterized by a very long X-ray bursting activity that lasts about 1500 s, one of the longest ever observed by BeppoSAX. In particular, a precursor and a late flare are present in the light curve. We connect the late X-ray flare observed at about 1300 s to the afterglow emission observed by Chandra and associate it with the onset of the afterglow emission in the framework of ext...

  4. Coincident Observation of Lightning using Spaceborne Spectrophotometer and Ground-Level Electromagnetic Sensors

    Adachi, Toru; Cohen, Morris; Li, Jingbo; Cummer, Steve; Blakeslee, Richard; Marshall, THomas; Stolzenberg, Maribeth; Karunarathne, Sumedhe; Hsu, Rue-Ron; Su, Han-Tzong; Chen, Alfred; Takahashi, Yukihiro; Frey, Harald; Mende, Stephen

    2012-01-01

    The present study aims at assessing a possible new way to reveal the properties of lightning flash, using spectrophotometric data obtained by FORMOSAT-2/ISUAL which is the first spaceborne multicolor lightning detector. The ISUAL data was analyzed in conjunction with ground ]based electromagnetic data obtained by Duke magnetic field sensors, NLDN, North Alabama Lightning Mapping Array (LMA), and Kennedy Space Center (KSC) electric field antennas. We first classified the observed events into cloud ]to ]ground (CG) and intra ]cloud (IC) lightning based on the Duke and NLDN measurements and analyzed ISUAL data to clarify their optical characteristics. It was found that the ISUAL optical waveform of CG lightning was strongly correlated with the current moment waveform, suggesting that it is possible to evaluate the electrical properties of lightning from satellite optical measurement to some extent. The ISUAL data also indicated that the color of CG lightning turned to red at the time of return stroke while the color of IC pulses remained unchanged. Furthermore, in one CG event which was simultaneously detected by ISUAL and LMA, the observed optical emissions slowly turned red as the altitude of optical source gradually decreased. All of these results indicate that the color of lightning flash depends on the source altitude and suggest that spaceborne optical measurement could be a new tool to discriminate CG and IC lightning. In the presentation, we will also show results on the comparison between the ISUAL and KSC electric field data to clarify characteristics of each lightning process such as preliminary breakdown, return stroke, and subsequent upward illumination.

  5. Levels and Rates of Physical Activity in Older Adults with Multiple Sclerosis

    Klaren, Rachel E; Sebastiao, Emerson; Chiu, Chung-Yi; Kinnett-Hopkins, Dominique; McAuley, Edward; Motl, Robert W.

    2016-01-01

    There is much evidence supporting the safety and benefits of physical activity in adults with multiple sclerosis (MS) and recent evidence of beneficial effects on physical function in older adults with MS. However, there is very little known about physical activity participation in older adults with conditions such as MS. This study compared levels of physical activity (i.e., sedentary behavior, light physical activity (LPA), and moderate-to-vigorous physical activity (MVPA)) and rates of mee...

  6. Activity concentrations of natural radionuclide levels in well waters of Ago Iwoye, Nigeria

    Natural Radioactivity, though natural requires concentration monitoring, especially for the health/ environmental checks of the populace. Materials and Methods; The activity concentrations of 40K, 238U and 232Th in the waters from wells with depths ranging between 141.0 214.0 feet were randomly sampled and determined from 20 locations in Ago-Iwoye town in South Western, Nigeria. Results: The activity concentrations obtained were in the ranges of (9.9-50.9)Bq/kg with mean value of (25.1±10.7) Bq/kg for 40K, (BDL-15.0) Bq/kg with mean value of (1.2±3.2) Bq/kg for 238U and (BDL-6.2) Bq/kg with mean value of (1.6±1.7) Bq/kg for 232Th. Conclusion: According to the results obtained for the activity concentrations from 20 well water samples in Ago Iwoye, Southwestern, Nigeria it was observed that the V40K, 238U and 232Th values were still within the tolerance level indicating minimal radiological health burden on the human populace and the environment.

  7. Union Activities to promote cooperative activities at enterprise level: workplace assesment

    Jensen, Per Langå; Høy, Jette

    1996-01-01

    An analysis of the information activities on workplace assessment from a major Danish confederation......An analysis of the information activities on workplace assessment from a major Danish confederation...

  8. Self-reported activity level and knee function in amateur football players

    Frobell, R B; Svensson, E; Göthrick, M;

    2008-01-01

    ) amateur football players in 10 football clubs from each division below national level participated in the study. Self-reported Tegner Activity Scale, and the Knee injury and Osteoarthritis Outcome Score (KOOS) are the main outcome measures. Older age, female gender and lower level of competition (football...... recommended. We suggest that self-reported Tegner Activity Scale scores should be adjusted for age, gender and level of competition. In amateur football players, KOOS scores do not need adjustment for age and gender....

  9. Platelet activation determines angiopoietin-1 and VEGF levels in malaria: implications for their use as biomarkers.

    Judith Brouwers

    Full Text Available INTRODUCTION: The angiogenic proteins angiopoietin (Ang-1, Ang-2 and vascular endothelial growth factor (VEGF are regulators of endothelial inflammation and integrity. Since platelets store large amounts of Ang-1 and VEGF, measurement of circulation levels of these proteins is sensitive to platelet number, in vivo platelet activation and inadvertent platelet activation during blood processing. We studied plasma Ang-1, Ang-2 and VEGF levels in malaria patients, taking the necessary precautions to avoid ex vivo platelet activation, and related plasma levels to platelet count and the soluble platelet activation markers P-selectin and CXCL7. METHODS: Plasma levels of Ang-1, Ang-2, VEGF, P-selectin and CXCL7 were measured in CTAD plasma, minimizing ex vivo platelet activation, in 27 patients with febrile Plasmodium falciparum malaria at presentation and day 2 and 5 of treatment and in 25 healthy controls. RESULTS: Levels of Ang-1, Ang-2 and VEGF were higher at day 0 in malaria patients compared to healthy controls. Ang-2 levels, which is a marker of endothelial activation, decreased after start of antimalarial treatment. In contrast, Ang-1 and VEGF plasma levels increased and this corresponded with the increase in platelet number. Soluble P-selectin and CXCL7 levels followed the same trend as Ang-1 and VEGF levels. Plasma levels of these four proteins correlated strongly in malaria patients, but only moderately in controls. CONCLUSION: In contrast to previous studies, we found elevated plasma levels of Ang-1 and VEGF in patients with malaria resulting from in vivo platelet activation. Ang-1 release from platelets may be important to dampen the disturbing effects of Ang-2 on the endothelium. Evaluation of plasma levels of these angiogenic proteins requires close adherence to a stringent protocol to minimize ex vivo platelet activation.

  10. Observations of the high vibrational levels of the B('')B̄ (1)Σ(u)(+) state of H2.

    Chartrand, A M; Duan, W; Ekey, R C; McCormack, E F

    2016-01-01

    Double-resonance laser spectroscopy via the EF (1)Σg (+),v(')=6,J(')=0-2 state was used to probe the high vibrational levels of the B('')B̄ (1)Σu (+) state of molecular hydrogen. Resonantly enhanced multiphoton ionization spectra were recorded by detecting ion production as a function of energy using a time of flight mass spectrometer. New measurements of energies for the v = 51-66 levels for the B('')B̄ state of H2 are reported, which, taken with previous results, span the v = 46-69 vibrational levels. Results for energy levels are compared to theoretical close-coupled calculations [L. Wolniewicz, T. Orlikowski, and G. Staszewska, J. Mol. Spectrosc. 238, 118-126 (2006)]. The average difference between the 84 measured energies and calculated energies is -3.8 cm(-1) with a standard deviation of 5.3 cm(-1). This level of agreement showcases the success of the theoretical calculations in accounting for the strong rovibronic mixing of the (1)Σu (+) and (1)Πu (+) states. Due to the ion-pair character of the outer well, the observed energies of the vibrational levels below the third dissociation limit smoothly connect with previously observed energies of ion-pair states above this limit. The results provide an opportunity for testing a heavy Rydberg multi-channel quantum defect analysis of the high vibrational states below the third dissociation limit. PMID:26747806

  11. Participant observation of time allocation, direct patient contact and simultaneous activities in hospital physicians

    Zupanc Andrea

    2009-06-01

    Full Text Available Abstract Background Hospital physicians' time is a critical resource in medical care. Two aspects are of interest. First, the time spent in direct patient contact – a key principle of effective medical care. Second, simultaneous task performance ('multitasking' which may contribute to medical error, impaired safety behaviour, and stress. There is a call for instruments to assess these aspects. A preliminary study to gain insight into activity patterns, time allocation and simultaneous activities of hospital physicians was carried out. Therefore an observation instrument for time-motion-studies in hospital settings was developed and tested. Methods 35 participant observations of internists and surgeons of a German municipal 300-bed hospital were conducted. Complete day shifts of hospital physicians on wards, emergency ward, intensive care unit, and operating room were continuously observed. Assessed variables of interest were time allocation, share of direct patient contact, and simultaneous activities. Inter-rater agreement of Kappa = .71 points to good reliability of the instrument. Results Hospital physicians spent 25.5% of their time at work in direct contact with patients. Most time was allocated to documentation and conversation with colleagues and nursing staff. Physicians performed parallel simultaneous activities for 17–20% of their work time. Communication with patients, documentation, and conversation with colleagues and nursing staff were the most frequently observed simultaneous activities. Applying logit-linear analyses, specific primary activities increase the probability of particular simultaneous activities. Conclusion Patient-related working time in hospitals is limited. The potential detrimental effects of frequently observed simultaneous activities on performance outcomes need further consideration.

  12. Determining Best Method for Estimating Observed Level of Maximum Detrainment based on Radar Reflectivity

    Carletta, Nicholas; Mullendore, Gretchen; Starzec, Mariusz; Xi, Baike; Feng, Zhe; Dong, Xiquan

    2016-07-25

    Convective mass transport is the transport of mass from near the surface up to the upper troposphere and lower stratosphere (UTLS) by a deep convective updraft. This transport can alter the chemical makeup and water vapor balance of the UTLS, which affects cloud formation and the radiative properties of the atmosphere. It is therefore important to understand the exact altitudes at which mass is detrained from convection. The purpose of this study was to improve upon previously published methodologies for estimating the level of maximum detrainment (LMD) within convection using data from a single ground-based radar. Four methods were used to identify the LMD and validated against dual-Doppler derived vertical mass divergence fields for six cases with a variety of storm types. The best method for locating the LMD was determined to be the method that used a reflectivity texture technique to determine convective cores and a multi-layer echo identification to determine anvil locations. Although an improvement over previously published methods, the new methodology still produced unreliable results in certain regimes. The methodology worked best when applied to mature updrafts, as the anvil needs time to grow to a detectable size. Thus, radar reflectivity is found to be valuable in estimating the LMD, but storm maturity must also be considered for best results.

  13. Impact of physical activity and fitness on the level of kinesiophobia in women of perimenopausal age

    Saulicz, Mariola; Saulicz, Edward; Knapik, Andrzej; Rottermund, Jerzy; Myśliwiec, Andrzej; Wolny, Tomasz

    2016-01-01

    To determine the impact of physical activity and fitness on the level of physical activity barriers (kinesiophobia) in women of perimenopausal age, the study included 105 women between the ages of 48 and 58. A Baecke questionnaire was used to evaluate physical activity and a modified Fullerton test was used to evaluate the fitness level. The level of kinesiophobia was assessed using the Kinesiophobia Causes Scale questionnaire. A low level of habitual physical activity has a negative impact on the values of Biological Domain (r = –0.581), Psychological Domain (r = –0.451), and on the Kinesiophobia Cause Scale total score (r = –0.577). Lower physical activity expressed by a lower score in the Fullerton test also has a negative impact on the level of kinesiophobia. Upper body flexibility (r = –0.434) has the strongest influence on the Biological Domain, whereas upper body strength (r = –0.598) has the greatest impact on the Psychological Domain. A low level of upper body strength also has the greatest impact on the Kinesiophobia Cause Scale total score (r = –0.507). Low levels of physical activity and fitness in women of perimenopausal age favour kinesiophobic attitudes and thereby increase the level of barriers against undertaking physical activity.

  14. Impact of physical activity and fitness on the level of kinesiophobia in women of perimenopausal age.

    Saulicz, Mariola; Saulicz, Edward; Knapik, Andrzej; Linek, Pawel; Rottermund, Jerzy; Myśliwiec, Andrzej; Wolny, Tomasz

    2016-06-01

    To determine the impact of physical activity and fitness on the level of physical activity barriers (kinesiophobia) in women of perimenopausal age, the study included 105 women between the ages of 48 and 58. A Baecke questionnaire was used to evaluate physical activity and a modified Fullerton test was used to evaluate the fitness level. The level of kinesiophobia was assessed using the Kinesiophobia Causes Scale questionnaire. A low level of habitual physical activity has a negative impact on the values of Biological Domain (r = -0.581), Psychological Domain (r = -0.451), and on the Kinesiophobia Cause Scale total score (r = -0.577). Lower physical activity expressed by a lower score in the Fullerton test also has a negative impact on the level of kinesiophobia. Upper body flexibility (r = -0.434) has the strongest influence on the Biological Domain, whereas upper body strength (r = -0.598) has the greatest impact on the Psychological Domain. A low level of upper body strength also has the greatest impact on the Kinesiophobia Cause Scale total score (r = -0.507). Low levels of physical activity and fitness in women of perimenopausal age favour kinesiophobic attitudes and thereby increase the level of barriers against undertaking physical activity. PMID:27582685

  15. Investigation of PON1 activity and MDA levels in patients with epilepsy not receiving antiepileptic treatment

    Dönmezdil N

    2016-04-01

    Full Text Available Nilüfer Dönmezdil, Mehmet Uğur Çevik, Hasan Hüseyin Özdemir, Muhterem Taşin Department of Neurology, Dicle University, Diyarbakır, Turkey Purpose: There are many studies dedicated to researching the etiopathogenesis of epilepsy. In such research, oxidative and antioxidant indicators of etiopathogenesis have also been examined under the scope. Drawing on a group of patients with epilepsy who were receiving no treatment, we have tried to evaluate whether or not an increase in oxidative indicators is linked directly with the disorder, independent of epileptic medicaments.Methods: Thirty people in good health and 30 newly diagnosed with epilepsy and who received ambulatory treatment in the polyclinic of the Neurology Department took part in the study. The tests relating to serum malondialdehyde (MDA levels and paraoxonase 1 (PON1 activity were carried out in the biochemistry laboratory.Results: Even though the levels of MDA in the patient group (14.34±3.59 nmol/mL were found to be high compared to those of the control group, which consisted of people in good health (13.53±3.56 nmol/mL, there was no statistically significant difference. PON1 activity in the serum taken from people in the patient group (0.65±0.17 was lower in comparison to that observed in the serum of the control group (0.71±0.17 U/L. Nonetheless, it was not so low as to have significance from a statistical point of view.Conclusion: We conclude that such a high level of oxidative parameters should have been related to the disease and that statistically significant findings that emerged in some other studies could have been related to an antiepileptic treatment. Keywords: epilepsy, paraoxonase 1, malondialdehyde, oxidative stress, epilepsy, biochemical marker

  16. Leisure activity associated with cognitive ability level, but not cognitive change

    Gow, Alan John; Avlund, Kirsten; Mortensen, Erik L

    2014-01-01

    Although activity participation is promoted as cognitively protective, critical questions of causality remain. In a cohort followed every 5 years from age 75 to 85 years, potential reciprocal associations between level and change in leisure activity participation and level and change in cognitive...... abilities were examined. Participants in the Glostrup 1914 Cohort, a longitudinal study of aging, completed standardized cognitive ability tests and reported their leisure activity participation (11 activities defined a leisure activity score) at ages 75, 80, and 85. Higher leisure activity was associated...... with higher cognitive ability (significant correlations ranged from 0.15 to 0.31, p < 0.05). Between ages 75 and 85, participation in leisure activities and cognitive ability declined significantly. Growth curve models, which provided latent variables for level of and 10-year change in both leisure...

  17. Optimal strategies for observation of active galactic nuclei variability with Imaging Atmospheric Cherenkov Telescopes

    Giomi, Matteo; Maier, Gernot

    2016-01-01

    Variable emission is one of the defining characteristic of active galactic nuclei (AGN). While providing precious information on the nature and physics of the sources, variability is often challenging to observe with time- and field-of-view-limited astronomical observatories such as Imaging Atmospheric Cherenkov Telescopes (IACTs). In this work, we address two questions relevant for the observation of sources characterized by AGN-like variability: what is the most time-efficient way to detect such sources, and what is the observational bias that can be introduced by the choice of the observing strategy when conducting blind surveys of the sky. Different observing strategies are evaluated using simulated light curves and realistic instrument response functions of the Cherenkov Telescope Array (CTA), a future gamma-ray observatory. We show that strategies that makes use of very small observing windows, spread over large periods of time, allows for a faster detection of the source, and are less influenced by the...

  18. Marketing activities to promote the subjects of management of sports events of international level

    Попов [Aleksandr Popov], Олександр Вікторович

    2013-01-01

    Done identify the organizational and managerial conditions integrated marketing activities for the improvement of the sports events with international standards. Presents a comprehensive description of the conditions and management of marketing activities of entities conducting sports events of international level, which is the result of analysis of the literature, document analysis, systems analysis, survey. Established that a comprehensive marketing activities of sports organizations curren...

  19. Parent's Interests, Current Involvement and Level of Parental Involvement in School Activities.

    Gbadamosi, Tara; Lin, Huey-Ling

    This study examined what school activities parents were involved in and the relationship between parents' interests and level of participation. Parents completed self-report questionnaires examining activities they were currently involved in and activities they would like to do in their children's classrooms. Out of 208 surveys distributed, 114…

  20. Brain activation patterns resulting from learning letter forms through active self-production and passive observation in young children

    Alyssa J Kersey

    2013-09-01

    Full Text Available Although previous literature suggests that writing practice facilitates neural specialization for letters, it is unclear if this facilitation is driven by the perceptual feedback from the act of writing or the actual execution of the motor act. The present study addresses this issue by measuring the change in BOLD signal in response to hand-printed letters, unlearned cursive letters, and cursive letters that 7 year-old children learned actively, by writing, and passively, by observing an experimenter write. Brain activation was assessed using fMRI while perceiving letters – in both cursive and manuscript forms. Results showed that active training led to increased recruitment of the sensori-motor network associated with letter perception as well as the insula and claustrum, but passive observation did not. This suggests that perceptual networks for newly learned cursive letters are driven by motor execution rather than by perceptual feedback.

  1. Dynamically observing the value of the changes of serum sex hormone levels of early pregnancy after drug-induced abortion

    Objective: To observe the value of the changes of serum β-human chorionic gonadotropin (β-HCG), estradiol (E), progesterone (P) Levels of early pregnancy after drug-induced abortion dynamically. Methods: Assessing 55 women proved pregnant by urine or blood HCG retrospecticly, who had terminated their pregnancy by mifepristonr and misoprostol. Meanwhile the serum levels of β-HCG, E, P were monitored dynamically. Results: Among the 55 patients, the levels of β-HCG, E and P had significant decreased (tβ-HCG=4.845, tE=7.655, tP=11.390, PE=9.089, PP=2.910, P<0.05). Conclusion: Detectint the serum hormone's levels after drug-induced abortion by chemiluminescent immunoassay, we can assess indirectly the value of administration of mifepristone and misoprostol, predict the prolonged vaginal bleeding after drug-induced abortion, and the outcome of the treatment, which determine wether need another curestage. (authors)

  2. A touching sight: SII/PV activation during the observation and experience of touch.

    Keysers, Christian; Wicker, Bruno; Gazzola, Valeria; Anton, Jean-Luc; Fogassi, Leonardo; Gallese, Vittorio

    2004-04-22

    Watching the movie scene in which a tarantula crawls on James Bond's chest can make us literally shiver--as if the spider crawled on our own chest. What neural mechanisms are responsible for this "tactile empathy"? The observation of the actions of others activates the premotor cortex normally involved in the execution of the same actions. If a similar mechanism applies to the sight of touch, movies depicting touch should automatically activate the somatosensory cortex of the observer. Here we found using fMRI that the secondary but not the primary somatosensory cortex is activated both when the participants were touched and when they observed someone or something else getting touched by objects. The neural mechanisms enabling our own sensation of touch may therefore be a window also to our understanding of touch. PMID:15091347

  3. The influence of active seating on car passengers' perceived comfort and activity levels.

    Hiemstra-van Mastrigt, S; Kamp, I; van Veen, S A T; Vink, P; Bosch, T

    2015-03-01

    New technologies have led to an increasingly sedentary lifestyle. Sedentary behaviour is characterised by physical inactivity and is associated with several health risks. This excessive sitting does not only take place in the office or at home, but also during daily commute. Therefore, BMW AG developed an active seating system for the back seat of a car, consisting of sensors in the back rest that register upper body movements of the passenger, with which the passenger controls a game. This study evaluated three different aspects of active seating compared to other tasks (reading, working on laptop, and gaming on tablet). First, discomfort and comfort perception were measured in a 30-minute driving test. Discomfort was very low for all activities and participants felt significantly more challenged, more fit and more refreshed during active seating. Second, heart rate was measured, indicating a light intensity, but nevertheless non-sedentary, activity. Third, average and variability in activity of six postural muscles was measured by electromyography (EMG), showing a higher muscle activity and higher muscle variability for active seating compared to other activities. Active seating might stimulate movements, thereby increasing comfort and well-being. PMID:25479990

  4. Long term flaring activity of XRF 011030 observed with BeppoSAX

    Piro, A G L

    2005-01-01

    We present the spectral and temporal analysis of the X-ray flash XRF 011030 observed with BeppoSAX. This event is characterized by a very long X-ray bursting activity that lasts about 1500 s, the longest ever observed by BeppoSAX. In particular a precursor and a late flare are present in the light curve. We connect the late X-ray flare observed at about 1300 s to the afterglow emission observed by Chandra and associate it with the onset of the afterglow emission in the framework of external shock by a long duration engine activity. We find that the late X-ray flare and the broad-band afterglow data, including optical and radio measurements, are consistent either with a fireball expanding in a wind environment or with a jetted fireball in a ISM.

  5. Relationship between Resilience, Psychological Distress and Physical Activity in Cancer Patients: A Cross-Sectional Observation Study.

    Martin Matzka

    Full Text Available Psychological distress remains a major challenge in cancer care. The complexity of psychological symptoms in cancer patients requires multifaceted symptom management tailored to individual patient characteristics and active patient involvement. We assessed the relationship between resilience, psychological distress and physical activity in cancer patients to elucidate potential moderators of the identified relationships.A cross-sectional observational study to assess the prevalence of symptoms and supportive care needs of oncology patients undergoing chemotherapy, radiotherapy or chemo-radiation therapy in a tertiary oncology service. Resilience was assessed using the 10-item Connor-Davidson Resilience Scale (CD-RISC 10, social support was evaluated using the 12-item Multidimensional Scale of Perceived Social Support (MSPSS and both psychological distress and activity level were measured using corresponding subscales of the Rotterdam Symptom Checklist (RSCL. Socio-demographic and medical data were extracted from patient medical records. Correlation analyses were performed and structural equation modeling was employed to assess the associations between resilience, psychological distress and activity level as well as selected socio-demographic variables.Data from 343 patients were included in the analysis. Our revised model demonstrated an acceptable fit to the data (χ2(163 = 313.76, p = .000, comparative fit index (CFI = .942, Tucker-Lewis index (TLI = .923, root mean square error of approximation (RMSEA = .053, 90% CI [.044.062]. Resilience was negatively associated with psychological distress (β = -.59, and positively associated with activity level (β = .20. The relationship between resilience and psychological distress was moderated by age (β = -0.33 but not social support (β = .10, p = .12.Cancer patients with higher resilience, particularly older patients, experience lower psychological distress. Patients with higher resilience are

  6. Correlation between vitamin D levels and muscle fatigue risk factors based on physical activity in healthy older adults

    Al-Eisa, Einas S; Alghadir, Ahmad H; Gabr, Sami A

    2016-01-01

    Purpose The purpose of this study was to investigate the relationship of serum vitamin D levels with physical activity, obesity, muscle fatigue biomarkers, and total antioxidant capacity (TAC) in healthy older adults. Methods A total of 85 healthy older subjects aged 64–96 years were recruited in this study. Based on estimated energy expenditure scores, the participants were classified into three groups: inactive (n=25), moderate (n=20), and physically active (n=35). Serum 25(OH)D (25-hydroxy vitamin D) levels, metabolic syndrome parameters, TAC activity, muscle fatigue biomarkers (Ca, creatine kinase, lactic acid dehydrogenase, troponin I, hydroxyproline), physical activity, body fatness, and fatigue score (visual analog scale) were estimated using immunoassay techniques and prevalidated questionnaires, respectively. Results Physical activity was estimated in 64.6% of the participants. Males showed higher physical activity (42.5%) compared to females (26.25%). Compared to participants with lower activity, significant reduction in body mass index, waist circumference, hips, fasting blood sugar, triglycerides, total cholesterol, HDL-cholesterol, and LDL-cholesterol were observed in moderate and physically active participants. Also, significant increase in the levels of serum 25(OH)D concentrations, calcium, and TAC activity along with reduction in the levels of muscle fatigue biomarkers: creatine kinase, lactic acid dehydrogenase, troponin I, hydroxyproline, and fatigue scores (visual analog scale) were reported in physically active participants compared to those of lower physical activity. In all participants, serum 25(OH)D concentrations correlated positively with Ca, TAC, physical activity scores, and negatively with body mass index, lipid profile, fatigue scores (visual analog scale), and muscle fatigue biomarkers. Stepwise regression analysis showed that serum 25(OH)D concentrations, physical activity, Ca, TAC, and demographic parameters explained

  7. Effect of action observation therapy on daily activities and motor recovery in stroke patients

    Mei-Hong Zhu; Jing Wang; Xu-Dong Gu; Mei-Fang Shi; Ming Zeng; Chun-Yuan Wang; Qiao-Ying Chen; Jian-Ming Fu

    2015-01-01

    Objective: To evaluate the effects of action observation therapy, which is based on mirror neuron theory, on upper limb function and activities of daily living in patients with stroke. Methods: Sixty-one patients with stroke were randomly divided into two groups; those in the control group received routine rehabilitation treatment and nursing, whereas those in the experimental group additionally received eight weeks of action observation therapy for 30 min, six times per week. Patients rec...

  8. Attempting to be active: Self-efficacy and barrier limitation differentiate activity levels of working mothers.

    Gierc, Madelaine; Locke, Sean; Jung, Mary; Brawley, Lawrence

    2016-07-01

    Working mothers are less physically active than working women without children and mothers who do not work. The purpose of this study was to examine concurrent self-regulatory efficacy and barriers to physical activity in a sample of working mothers. Women completed a mixed-methods survey which included measures of physical activity, concurrent self-regulatory efficacy, and barriers. Sufficiently active women experienced significantly greater concurrent self-regulatory efficacy and significantly less barrier limitation and frequency. No significant group differences were found for age, domestic duties performed, and children's extracurricular activities. Thematic analysis of barriers revealed six themes of common and unique factors, including limited time and family activities. PMID:27357921

  9. Distribution and activity levels of matrix metalloproteinase 2 and 9 in canine and feline osteosarcoma.

    Gebhard, Christiane; Fuchs-Baumgartinger, Andrea; Razzazi-Fazeli, Ebrahim; Miller, Ingrid; Walter, Ingrid

    2016-01-01

    Overexpression of matrix metalloproteinases (MMPs) has been associated with increased tumor aggressiveness and metastasis dissemination. We investigated whether the contrasting metastatic behavior of feline and canine osteosarcoma is related to levels and activities of MMP2 and MMP9. Zymography and immunohistochemistry were used to determine expression levels of MMP2 and MMP9 in canine and feline osteosarcoma. Using immunohistochemistry, increased MMP9 levels were identified in most canine osteosarcomas, whereas cat samples more often displayed moderate levels. High levels of pro-MMP9, pro-MMP2, and active MMP2 were detected by gelatin zymography in both species, with significantly higher values for active MMP2 in canine osteosarcoma. These findings indicate that MMP2 is probably involved in canine and feline osteosarcoma and their expression and activity could be associated with the different metastatic behavior of canine and feline osteosarcoma. PMID:26733734

  10. Observation of excited level populations of Li-like aluminium ions in a recombining plasma: role of atomic processes involving doubly excited levels of Be-like ions

    An aluminium slab target was irradiated by multiple pulses of Nd:glass laser light with the irradiance of 1.5x1012 W cm-2. After the laser irradiation, a laser-produced aluminium plasma was observed in its recombining phase using a spectrometer whose relative sensitivity was calibrated. We measured relative intensities of the resonance series lines and the lines of the 2p2P-nd2D and 2p2P-ns2S series of the Li-like aluminium ions and derived the excited level populations of the upper levels. >From the slope of the population distribution of the high-lying excited levels and the transition from the series lines to the continuum, the electron temperature and the electron density were estimated to be 8 eV and 3.5x1025 m-3. A comparison of the experimental population distribution with a collisional-radiative (CR) model calculation indicates that recombination of the excited Li-like ions through doubly excited levels of the Be-like ions plays an important role in the population kinetics of the Li-like ions. (author)

  11. The Influence of Centre-Based Childcare on Preschoolers’ Physical Activity Levels: A Cross-Sectional Study

    Leigh M. Vanderloo

    2014-02-01

    Full Text Available The childcare environment represents an appropriate avenue to support physical activity among preschoolers. The aim of this study was two-fold: (1 to measure the physical activity levels of a sample of preschoolers during childcare hours; and (2 to assess which attributes (e.g., space, equipment, policies within centre-based childcare environments influenced physical activity. Thirty-one preschoolers from 5 childcare centres across London, Canada participated. Actical accelerometers were worn by participants for one day during childcare hours to assess activity levels using a 15 second epoch length. The Environment and Policy Assessment and Observation instrument was used to conduct a full-day evaluation of the childcare environment. On average, participants engaged in 1.54 min/h of moderate-to-vigorous physical activity and 17.42 min/h of total physical activity. Sedentary opportunities, portable and fixed play equipment, and staff behaviour accounted for 49.3% of the variability in moderate-to-vigorous physical activity and 14.1% of the variability in total physical activity, with sedentary opportunities, fixed play equipment, and staff behaviours displaying an inverse relationship. Results emphasize the critical role the childcare environment plays in supporting physical activity among preschoolers.

  12. EFFECTS OF CHRONIC STRESS ON THE ACTIVITIES OF SOD, GSH-Px AND MDA LEVEL IN FEMALE RATS' BRAIN

    王莹; 杨东伟; 谢雯; 庞炜; 蒋马莉; 韩太真

    2002-01-01

    Objective To observe the effects of chronic emotional stress on the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) and malonialdehyde (MDA) level in female rats' brain. Methods The rats were randomly divided into 4 groups: normal control group (group N), emotional stress group (group E), emotional stress + pregnancy group (group E+P) and regularly drinking group (group R). Emotional stress in rats was induced by training rats with empty drinking bottles. Having been finished the stress procedure, the brain was taken out and homogenized. Then the activities of SOD, GSH-Px and MDA level were measured. Results Compared to group N, both the activities of SOD in brain tissues of group E and group E+P were significantly decreased (P<0.05 and P<0.01, respectively) while the MDA level increased (P<0.05). However, the extent of changes in group E+P was more obvious than that in E. GSH-Px activities in E+P and E were significantly changed. However, the GSH-Px activity in E+P was decreased (P<0.05) while the activity in E increased (P<0.05).Conclusion The chronic emotional stress can reduce the antioxidative system by decreasing the antioxidative enzyme activity and potentiating the lipid peroxidation in the brain. It is also suggested that the combination of emotional stress and pregnancy can augment the oxidative damage in rats' brain.

  13. Versatile illumination platform and fast optical switch to give standard observation camera gated active imaging capacity

    Grasser, R.; Peyronneaudi, Benjamin; Yon, Kevin; Aubry, Marie

    2015-10-01

    CILAS, subsidiary of Airbus Defense and Space, develops, manufactures and sales laser-based optronics equipment for defense and homeland security applications. Part of its activity is related to active systems for threat detection, recognition and identification. Active surveillance and active imaging systems are often required to achieve identification capacity in case for long range observation in adverse conditions. In order to ease the deployment of active imaging systems often complex and expensive, CILAS suggests a new concept. It consists on the association of two apparatus working together. On one side, a patented versatile laser platform enables high peak power laser illumination for long range observation. On the other side, a small camera add-on works as a fast optical switch to select photons with specific time of flight only. The association of the versatile illumination platform and the fast optical switch presents itself as an independent body, so called "flash module", giving to virtually any passive observation systems gated active imaging capacity in NIR and SWIR.

  14. Relationship between self-reported dietary intake and physical activity levels among adolescents: The HELENA study

    Le Donne Cinzia

    2011-02-01

    Full Text Available Abstract Background Evidence suggests possible synergetic effects of multiple lifestyle behaviors on health risks like obesity and other health outcomes. Therefore it is important to investigate associations between dietary and physical activity behavior, the two most important lifestyle behaviors influencing our energy balance and body composition. The objective of the present study is to describe the relationship between energy, nutrient and food intake and the physical activity level among a large group of European adolescents. Methods The study comprised a total of 2176 adolescents (46.2% male from ten European cities participating in the HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence study. Dietary intake and physical activity were assessed using validated 24-h dietary recalls and self-reported questionnaires respectively. Analyses of covariance (ANCOVA were used to compare the energy and nutrient intake and the food consumption between groups of adolescents with different physical activity levels (1st to 3rd tertile. Results In both sexes no differences were found in energy intake between the levels of physical activity. The most active males showed a higher intake of polysaccharides, protein, water and vitamin C and a lower intake of saccharides compared to less active males. Females with the highest physical activity level consumed more polysaccharides compared to their least active peers. Male and female adolescents with the highest physical activity levels, consumed more fruit and milk products and less cheese compared to the least active adolescents. The most active males showed higher intakes of vegetables and meat, fish, eggs, meat substitutes and vegetarian products compared to the least active ones. The least active males reported the highest consumption of grain products and potatoes. Within the female group, significantly lower intakes of bread and cereal products and spreads were found for those reporting to

  15. Physical Activity Level of Urban Pregnant Women in Tianjin, China: A Cross-Sectional Study

    Zhang, Yan; Dong, Shengwen; Zuo, Jianhua; Hu, Xiangqin; Zhang, Hua; Zhao, Yue

    2014-01-01

    Objective To determine the physical activity level and factors influencing physical activity among pregnant urban Chinese women. Methods This prospective cross-sectional study enrolled 1056 pregnant women (18–44 years of age) in Tianjin, China. Their socio-demographic characteristics were recorded, and the Pregnancy Physical Activity Questionnaire was used to assess their physical activity during pregnancy. The data were analyzed by multinomial logistic regression with adjustment for potentia...

  16. Integrating Cooperative Learning Activities to Instruction at Tertiary Education Level: A Qualitative Portrayal of the Experience

    Irshad Hussain; Dr. Hafiz Muhammad Athar Khan; Shazia Ramzan

    2013-01-01

    This paper is a qualitative portrayal of personal experience of the author in which he engaged tertiary education students in cooperative learning activities in the classroom. It is based on his observational notes taken during instructional process, involvement of learners in cooperative learning activities, and their reflection on these activities. The experience focused on assessing the effectiveness of cooperative learning activities. It is described that the researcher taught a course on...

  17. Premonitory phenomenon of El Ni(n)o event reflected in the observations of LOD and sea level

    2000-01-01

    Data sets of the changes of the length of day, the sea surface temperature in the eastern Pacific and of the sea level in Hong Long from tide gauge observations are used to analyze and reveal the reflections in the observations of the length of day and the sea level changes concerned with the premonitory phenomenon of next El Ni(n)o event. The results from this study indicate that a new El Ni(n)o event has been brewing with the ending of the strong La Nina event that started in early summer of 1998. The estimated formation period of the new El Ni(n)o event will begin before the end of 2000, and the peak period may be reached at around the end of 2001.

  18. CAN A LONG NANOFLARE STORM EXPLAIN THE OBSERVED EMISSION MEASURE DISTRIBUTIONS IN ACTIVE REGION CORES?

    All theories that attempt to explain the heating of the high-temperature plasma observed in the solar corona are based on short bursts of energy. The intensities and velocities measured in the cores of quiescent active regions, however, can be steady over many hours of observation. One heating scenario that has been proposed to reconcile such observations with impulsive heating models is the 'long nanoflare storm', where short-duration heating events occur infrequently on many sub-resolution strands; the emission of the strands is then averaged together to explain the observed steady structures. In this Letter, we examine the emission measure distribution predicted for such a long nanoflare storm by modeling an arcade of strands in an active region core. Comparisons of the computed emission measure distributions with recent observations indicate that the long nanoflare storm scenario implies greater than five times more 1 MK emission than is actually observed for all plausible combinations of loop lengths, heating rates, and abundances. We conjecture that if the plasma had 'super coronal' abundances, the model may be able to match the observations at low temperatures.

  19. Observation of Energy Levels Quantization in Underdamped Josephson Junctions above the Classical-Quantum Regime Crossover Temperature

    We present a clear observation of the presence of energy levels quantization in high quality Nb-AlOx -Nb underdamped Josephson junctions at temperatures above the quantum crossover temperature. This has been possible by extending the measurements of the escape rate out of the zero-voltage state at higher sweeping frequency (dI/dt up to 25A/sec) in order to induce nonstationary conditions in the energy potential describing the junction dynamics. copyright 1997 The American Physical Society

  20. Observations of a doubly driven V system probed to a fourth level in laser-cooled rubidium

    D'Echaniz, S R; Durrant, A V; Segal, D M; Marangos, J P; Vaccaro, J A; Greentree, Andrew D.

    2001-01-01

    Observations of a doubly driven V system probed to a fourth level in an N configuration are reported. A dressed state analysis is also presented. The expected three-peak spectrum is explored in a cold rubidium sample in a magneto-optic trap. Good agreement is found between the dressed state theory and the experimental spectra once light shifts and uncoupled absorptions in the rubidium system are taken into account.

  1. Observations and Predictions of Wave Runup, Extreme Water Levels, and Medium-Term Dune Erosion during Storm Conditions

    Serge Suanez

    2015-07-01

    Full Text Available Monitoring of dune erosion and accretion on the high-energy macrotidal Vougot beach in North Brittany (France over the past decade (2004–2014 has revealed significant morphological changes. Dune toe erosion/accretion records have been compared with extreme water level measurements, defined as the sum of (i astronomic tide; (ii storm surge; and (iii vertical wave runup. Runup parameterization was conducted using swash limits, beach profiles, and hydrodynamic (Hm0, Tm0,–1, and high tide water level—HTWL data sets obtained from high frequency field surveys. The aim was to quantify in-situ environmental conditions and dimensional swash parameters for the best calibration of Battjes [1] runup formula. In addition, an empirical equation based on observed tidal water level and offshore wave height was produced to estimate extreme water levels over the whole period of dune morphological change monitoring. A good correlation between this empirical equation (1.01Hmoξo and field runup measurements (Rmax was obtained (R2 85%. The goodness of fit given by the RMSE was about 0.29 m. A good relationship was noticed between dune erosion and high water levels when the water levels exceeded the dune foot elevation. In contrast, when extreme water levels were below the height of the toe of the dune sediment budget increased, inducing foredune recovery. These erosion and accretion phases may be related to the North Atlantic Oscillation Index.

  2. Physical activity, cognitive performance, and academic achievement: an observational study in Dutch adolescents using accelerometers

    Van Dijk, Martin; De Groot, Renate; Savelberg, Hans; Van Acker, Frederik; Kirschner, Paul A.

    2013-01-01

    Van Dijk, M. L., De Groot, R. H. M., Savelberg, H. C. M., Van Acker, F. H. M., & Kirschner, P. A. (2013, 7 November). Physical activity, cognitive performance, and academic achievement: an observational study in Dutch adolescents using accelerometers. Paper presentation at ICO National Fall School 2

  3. Physical activity, cognitive performance, and academic achievement: an observational study in Dutch adolescents using accelerometers

    Van Dijk, Martin; De Groot, Renate; Savelberg, Hans; Van Acker, Frederik; Kirschner, Paul A.

    2013-01-01

    Van Dijk, M. L., De Groot, R. H. M., Savelberg, H. C. M., Van Acker, F. H. M., & Kirschner, P. A. (2013, 7 November). Physical activity, cognitive performance, and academic achievement: an observational study in Dutch adolescents using accelerometers. Paper presentation at ICO National Fall School 2013, Maastricht, The Netherlands.

  4. Assimilation of active microwave observation data for soil moisture profile estimation

    Hoeben, R.; Troch, P.A.

    2000-01-01

    This paper discusses the potential of retrieving information about the soil moisture profile from measurements of the surface soil moisture content through active microwave observations of the Earth. Recently, Mancini et al. [1999] have shown through laboratory experiments that the volumetric moistu

  5. PeV Neutrinos Observed by IceCube from Cores of Active Galactic Nuclei

    Stecker, Floyd W.

    2013-01-01

    I show that the high energy neutrino flux predicted to arise from active galactic nuclei cores can explain the PeV neutrinos detected by IceCube without conflicting with the constraints from the observed extragalactic cosmic-ray and gamma-ray backgrounds.

  6. Present and future of high resolution radio observations of active galactic nuclei

    Using Cygnus A and 3C273 as examples, an introduction to radio interferometric observations of active galactic nuclei is made. Some aspects of present day research in extended and compact radio sources are presented. New instruments which are being presently built or planned and their possible scientific impact are discussed

  7. Observation of Hysteresis between Solar Activity Indicators and -mode Frequency Shifts for Solar Cycle 22

    S. C. Tripathy; Brajesh Kumar; Kiran Jain; A. Bhatnagar

    2000-09-01

    Using intermediate degree p-mode frequency data sets for solar cycle 22, we find that the frequency shifts and magnetic activity indicators show a ``hysteresis" phenomenon. It is observed that the magnetic indices follow different paths for the ascending and descending phases of the solar cycle while for radiative indices, the separation between the paths are well within the error limits.

  8. High IL-23 level is a marker of disease activity in rheumatoid arthritis.

    Abu Al Fadl, Esam M; Fattouh, Mona; Allam, Ahmed A

    2013-01-01

    Rheumatoid arthritis (RA) is a chronic autoimmune systemic disorder characterized by inflammatory responses mainly affecting the synovial joints. Interleukin-23 (IL-23) is a heterodimeric pro-inflammatory cytokine secreted by activated dendritic cells and activated macrophages. IL-23 is the key cytokine controlling inflammation in peripheral tissues leading to the development of autoimmune diseases. The objective of our study was to determine the relationship between the IL-23 level and disease activity in RA patients. Sixty RA patients were included in the study with mean age of 40 years; they included 44 (73.3 %) females and 16 males (26.7 %). The clinical parameters of disease activity were determined, including the 28-joint disease activity score (DAS28), serum levels of C-reactive protein (CRP), Anti-citrullinated peptide antibody (ACPA), rheumatoid factor (RF), and TNF-alpha and the degree of bony erosions based on X-rays. Patients were subdivided into active disease group (n = 30) with DAS28 score higher than 5.1 (Group I); and remission group (n = 30) with DAS28 score less than 2.6 (Group II). Thirty healthy individuals in the same age group of RA patients including 22 (73.3%) females and 8 males (26.7%) were randomly selected as the control group (Group III). The levels of IL-23 were determined by enzyme-linked immunosorbent assay (ELISA) and the correlations between the serum levels of IL-23 and disease activity parameters of patients with RA were determined. Serum levels of IL-23 were significantly higher in RA patients during active stage of the disease in comparison to the patients in remission and the control group. There was a significant positive correlation between serum IL-23 levels in RA patients and individual disease activity parameters. It is concluded that elevated serum IL-23 level may be a useful marker to detect active RA and disease progression in patients with RA. PMID:24617049

  9. Identifying meaningful activities among elderly people with demenitia: the developing process of an observation taxonomy

    Andresen, Mette

    2014-01-01

    Abstract title Identifying meaningful activities among elderly people with demenitia: the developing process of an observation taxonomy Abstract text Background: There is a need for tools to assist staff in identifying and planning meaningful activities for elderly nursing home residents with mod......Abstract title Identifying meaningful activities among elderly people with demenitia: the developing process of an observation taxonomy Abstract text Background: There is a need for tools to assist staff in identifying and planning meaningful activities for elderly nursing home residents...... with moderate and progressive dementia. Daily routines in nursing homes calls for a simple and easy-to-use tool which can fit into daily life and which can be used when and wherever during day and night. The theory of Tom Kitwood which focus on the importance of putting the demented persons wishes, habits......, values and beliefs in the center formed the base in the development of the tool. Aim: To develop an observational tool which can identify meaningful activities among elderly demented nursing home residents and thereby provide staff with more knowledge and possibilities for inviting and engaging residents...

  10. A case control study of premorbid and currently reported physical activity levels in chronic fatigue syndrome

    Buchwald Dedra

    2006-11-01

    Full Text Available Abstract Background Patients with chronic fatigue syndrome typically report high levels of physical activity before becoming ill. Few studies have examined premorbid and current activity levels in chronically fatigued patients. Methods In a case-control study, 33 patients with chronic, unexplained, disabling fatigue attending a university-based clinic specializing in fatigue were compared to 33 healthy, age- and sex-matched controls. Patients rated their activity levels before their illness and currently, using scales designed for this purpose. Controls reported their level of activity of 2 years previously and currently. Chi-square analyses, Student's t tests, and Wilcoxon signed rank tests were used in pair matched analyses. Results Compared to healthy controls, patients with chronic, unexplained fatigue rated themselves as more active before their illness (p ≤ 0.001 and less active currently (p ≤ 0.001. The patients also reported they currently stood or walked less than the controls (median [inter-quartile range] = 4 2345 versus 9 [7.5–12] hours, p ≤ 0.001, and spent more time reclining (median [inter-quartile range] = 12 10111213141516 versus 8 [8–9.5] hours, p ≤ 0.001. These differences remained significant for the subset of patients who met strict criteria for chronic fatigue syndrome or fibromyalgia. Conclusion Patients with chronic, unexplained, disabling fatigue reported being more active before becoming ill than healthy controls. This finding could be explained by greater premorbid activity levels that could predispose to illness, or by an overestimation of previous activity. Either possibility could influence patients' perceptions of their current activity levels and their judgments of recovery. Perceived activity should be addressed as part of management of the illness.

  11. Plasma levels of sRAGE, loss of aeration and weaning failure in ICU patients: a prospective observational multicenter study.

    Matthieu Jabaudon

    Full Text Available RATIONALE: Postextubation distress after a successful spontaneous breathing trial (SBT is associated with increased morbidity and mortality. Lung ultrasound determination of changes in lung aeration predicts weaning failure. It remains unknown whether this derecruitment is related to alveolar epithelial dysfunction or not. OBJECTIVE: To verify whether lung alveolar type I epithelial cell injury marker sRAGE (soluble form of the receptor for advanced glycation end-products is predictive of postextubation distress and weaning failure or not, and to verify whether plasma sRAGE levels can be related to lung derecruitment during the process of weaning from mechanical ventilation or not. INTERVENTIONS MEASUREMENTS: 88 patients from 2 intensive care units were included in this observational prospective study. Plasma sRAGE levels were measured in duplicate by ELISA before, at the end of a 60-minute SBT, and 4 hours after extubation. To quantify lung aeration, a lung ultrasound score was calculated. MAIN RESULTS: 34% of extubated patients experienced postextubation distress. Patients with or without postextubation distress had comparable sRAGE levels before SBT, after SBT, and 4 hours after extubation. In patients with postextubation distress, sRAGE levels were not predictive of the need for mechanical ventilation. sRAGE levels were not associated with lung aeration as assessed by echography. Patients who succeeded SBT (86% and those who failed (14% had no differences in sRAGE levels, before (median 1111 vs 1021 pg/mL, p = 0,87 and at the end of SBT (1165 vs 1038 pg/mL, p = 0.74. CONCLUSIONS: Plasma levels of sRAGE do not predict postextubation distress or SBT failure/success in patients weaning from mechanical ventilation. Lung aeration loss during a successful weaning trial predicts postextubation distress, but may not be evaluable by plasma levels of sRAGE, a marker of alveolar type I epithelial cell injury. TRIAL REGISTRATION: Clinical

  12. EEG Analysis of the Brain Activity during the Observation of Commercial, Political, or Public Service Announcements

    Giovanni Vecchiato

    2010-01-01

    Full Text Available The use of modern brain imaging techniques could be useful to understand what brain areas are involved in the observation of video clips related to commercial advertising, as well as for the support of political campaigns, and also the areas of Public Service Announcements (PSAs. In this paper we describe the capability of tracking brain activity during the observation of commercials, political spots, and PSAs with advanced high-resolution EEG statistical techniques in time and frequency domains in a group of normal subjects. We analyzed the statistically significant cortical spectral power activity in different frequency bands during the observation of a commercial video clip related to the use of a beer in a group of 13 normal subjects. In addition, a TV speech of the Prime Minister of Italy was analyzed in two groups of swing and “supporter” voters. Results suggested that the cortical activity during the observation of commercial spots could vary consistently across the spot. This fact suggest the possibility to remove the parts of the spot that are not particularly attractive by using those cerebral indexes. The cortical activity during the observation of the political speech indicated a major cortical activity in the supporters group when compared to the swing voters. In this case, it is possible to conclude that the communication proposed has failed to raise attention or interest on swing voters. In conclusions, high-resolution EEG statistical techniques have been proved to able to generate useful insights about the particular fruition of TV messages, related to both commercial as well as political fields.

  13. A Prospective, Longitudinal Study of Patient Activity Levels Following Total Knee Arthroplasty Stratified by Demographic and Comorbid Factors.

    Issa, Kimona; Jauregui, Julio J; Given, Kristin; Harwin, Steven F; Mont, Michael A

    2015-08-01

    With the marked increase in the annual number of total knee arthroplasties (TKAs) in the United States, there has been an increased interest in evaluating patient-reported outcomes. The purpose of this study was to prospectively and longitudinally evaluate temporal trends in patient activity levels following TKA and to identify potential demographic and comorbid factors that may affect these outcomes. This prospective study evaluated 281 patients, including 108 men and 173 women, who had a mean age of 66 years (39-80 years) and underwent primary TKA. All patients were followed for a minimum of 2 years. Medical comorbidities were recorded preoperatively and activity scores were evaluated at each follow-up visit. The effects of different patient demographics and systemic comorbidities on activity outcomes were further analyzed using multivariate regression analysis. Compared with preoperative levels, the activity score was observed to initially significantly decrease at 6 weeks postoperatively to below preoperative levels (9.2 vs. 8.1 points). By 3 months, scores were above preoperative levels (10.3 points), but below peak levels. A significant peak in the activity score was observed at 2-year follow-up after which there were no significant differences in scores at 5 years (11.49 vs. 11.47 points). In evaluating patient demographics and comorbidities, significant negative impact of older age, tobacco use, history of cancer, cardiovascular disease, lymphatic disease, and renal disease can be seen on activity levels. Activity scores following TKA follow a temporal trend in which scores initially drop below preoperative levels after surgery, but recover and reach a peak at 2 years postoperatively. This peak was maintained at 5-year follow-up. Surgeons should counsel their patients that they will not perceive the full benefit of a TKA until 1 to 2 years after surgery, in addition, patients may actually perceive their progress to decrease initially. Also, their

  14. High source levels and small active space of high pitched song in bowhead whales (Balaena mysticetus)

    Tervo, Outi Maria; Christoffersen, Mads F.; Simon, Malene;

    2012-01-01

    whales, estimate source levels and measure ambient noise. The song had a mean apparent source level of 185 ± 2 dB rms re 1µPa and a high mean centroid frequency of 444 ± 48 Hz. Using measured ambient noise levels in the area and Arctic sound spreading models, the estimated active space of these song...... attenuation. Here we evaluate the active space of high-pitched song notes of bowhead whales (Balaena mysticetus) in Western Greenland using measurements of song source levels and ambient noise. Four independent GPS-synchronized hydrophones were deployed through holes in the ice to localize vocalizing bowhead...... notes is between 40 and 130 km, an order of magnitude smaller than the estimated active space of low frequency blue and fin whale songs produced at similar source levels and for similar noise conditions. We propose that bowhead whales spatially compensate for their smaller communication range through...

  15. Elevated serum IL-10 levels in diffuse large B-cell lymphoma: a mechanism of aberrant JAK2 activation

    Gupta, Mamta; Han, Jing Jing; Stenson, Mary; Maurer, Matthew; Wellik, Linda; Hu, Guangzhen; Ziesmer, Steve; Dogan, Ahmet; Witzig, Thomas E.

    2012-01-01

    Cytokines are deregulated in cancers and can contribute to tumor growth. In patients with diffuse large-cell lymphoma (DLBCL), we observed higher levels of JAK/STAT pathway-related serum cytokines (ie, IL-6, IL-10, epidermal growth factor, and IL-2) compared with controls. Of these, only IL-10 activated the JAK2 pathway in lymphoma cells in vitro. Patients with high serum IL-10 had shorter event-free survival (EFS) than patients with low levels (P > .01) and high IL-10 was correlated with hig...

  16. THE RELATIONSHIP BETWEEN ELEMENTARY SCHOOL EIGHTH GRADE STUDENTS' PHYSICAL ACTIVITY LEVEL AND VARIOUS ANTHROPOMETRIC CHARACTERISTICS WITH THEIR ACADEMIC ACHIEVEMENT

    Halil

    2014-04-01

    Full Text Available The purpose of this study is to evaluate the relationship between elementary school eight grade students' physical activity level, their various anthropometric characteristics and their academic achievement. The participants of the study includes randomly chosen 324 volunteer eight grade students (n=168 female, n=156 male from 12 different elementary schools located in the central towns of the city, Konya (Selçuklu, Meram, Karatay in 2011-2012 Academic Year. The students' physical activity levels were assessed through the Turkish adaptation version of the Physical Activity Questionnaire for Older Children (PAQ-C 4-8 developed and tested in terms of validity and reliability by Crocker et al (1997. To determine the students' anthropometric characteristics, measurement of length and weight as well as bioelectiric impedence analysis (BIA were utilized. As an indicator of the students' academic achievement, the students' results in The National Placement Exam in 2012 were used. It was observed that there is no significant relationship between the students' physical activity level, their various anthropometric characteristics (their length and their academic achievement (r=.11 ve .13; p.05. It was observed that in male students, there is a low relationship between their length and academic achievement (r=.21; p.05 respectively.

  17. Multi-scale meteorological conceptual analysis of observed active fire hotspot activity and smoke optical depth in the Maritime Continent

    J. S. Reid

    2012-02-01

    Full Text Available Much research and speculation exists about the meteorological and climatological impacts of biomass burning in the Maritime Continent (MC of Indonesia and Malaysia, particularly during El Nino events. However, the MC hosts some of the world's most complicated meteorology, and we wish to understand how tropical phenomena at a range of scales influence observed burning activity. Using Moderate Resolution Imaging Spectroradiometer (MODIS derived active fire hotspot patterns coupled with aerosol data assimilation products, satellite based precipitation, and meteorological indices, the meteorological context of observed fire prevalence and smoke optical depth in the MC are examined. Relationships of burning and smoke transport to such meteorological and climatic factors as the interannual El Nino-Southern Oscillation (ENSO, El Nino Modoki, Indian Ocean Dipole (IOD, the seasonal migration of the Intertropical Convergence Zone, the 30–90 day Madden Julian Oscillation (MJO, tropical waves, tropical cyclone activity, and diurnal convection were investigated. A conceptual model of how all of the differing meteorological scales affect fire activity is presented. Each island and its internal geography have different sensitivities to these factors which are likely relatable to precipitation patterns and land use practices. At the broadest scales as previously reported, we corroborate ENSO is indeed the largest factor. However, burning is also enhanced by periods of El Nino Modoki. Conversely, IOD influences are unclear. While interannual phenomena correlate to total seasonal burning, the MJO largely controls when visible burning occurs. High frequency phenomena which are poorly constrained in models such as diurnal convection and tropical cyclone activity also have an impact which cannot be ignored. Finally, we emphasize that these phenomena not only influence burning, but also the observability of burning, further complicating our ability to assign

  18. Muscle activity, time to fatigue, and maximum task duration at different levels of production standard time

    Nur, Nurhayati Mohd; Dawal, Siti Zawiah Md; Dahari, Mahidzal; Sanusi, Junedah

    2015-01-01

    [Purpose] This study investigated the variations in muscle fatigue, time to fatigue, and maximum task duration at different levels of production standard time. [Methods] Twenty subjects performed repetitive tasks at three different levels of production standard time corresponding to “normal”, “hard” and “very hard”. Surface electromyography was used to measure the muscle activity. [Results] The results showed that muscle activity was significantly affected by the production standard time leve...

  19. Physical activity level, musculoskeletal fitness,balance, strength and power performance in older adults

    Lohne-Seiler, Hilde

    2015-01-01

    The link between physical activity and prevention of disease, maintenance of independence, and improved quality of life in older adults is supported by strong evidence. However, there is a lack of data on population levels where physical activity level has been measured objectively in association with self-reported health, musculoskeletal fitness and balance variables in older men and women. Also, little is known about the functional adaptive responses of older adults to pow...

  20. Forecasting activity levels in the UK continental shelf. The role of perceptions

    The explicit treatment of the role of perceptions in modelling forecasts is uncommon. With respect to future activity levels in the UK Continental Shelf, using the flexibility of add factors in econometric forecasts, this article demonstrates that, in addition to price variations, forecasts are sensitive to perceptions about future resource discovery and recovery rates. A medium-sized multivariate system reflecting the feedback structure of the petroleum supply process was formulated, estimated, and used to forecast activity levels

  1. Do enhancements to the urban built environment improve physical activity levels among socially disadvantaged populations?

    Maddison Ralph; Pearce Jamie R

    2011-01-01

    Abstract Background There is growing recognition that the urban built environment influences physical activity at the population level, although the effects on disadvantaged groups are less well understood. Using the examples of open/green space and street connectivity, this paper explores whether enhancements to the built environment have potential for addressing physical activity-related health inequalities among Māori, Pacific and low income communities in New Zealand. Method A high-level ...

  2. Platelet Activation Determines Angiopoietin-1 and VEGF Levels in Malaria: Implications for Their Use as Biomarkers

    Judith Brouwers; Rintis Noviyanti; Rob Fijnheer; de Groot, Philip G.; Leily Trianty; Siti Mudaliana; Mark Roest; Din Syafruddin; Andre van der Ven; Quirijn de Mast

    2013-01-01

    INTRODUCTION: The angiogenic proteins angiopoietin (Ang)-1, Ang-2 and vascular endothelial growth factor (VEGF) are regulators of endothelial inflammation and integrity. Since platelets store large amounts of Ang-1 and VEGF, measurement of circulation levels of these proteins is sensitive to platelet number, in vivo platelet activation and inadvertent platelet activation during blood processing. We studied plasma Ang-1, Ang-2 and VEGF levels in malaria patients, taking the necessary precautio...

  3. Optimal strategies for observation of active galactic nuclei variability with Imaging Atmospheric Cherenkov Telescopes

    Giomi, Matteo; Gerard, Lucie; Maier, Gernot

    2016-07-01

    Variable emission is one of the defining characteristic of active galactic nuclei (AGN). While providing precious information on the nature and physics of the sources, variability is often challenging to observe with time- and field-of-view-limited astronomical observatories such as Imaging Atmospheric Cherenkov Telescopes (IACTs). In this work, we address two questions relevant for the observation of sources characterized by AGN-like variability: what is the most time-efficient way to detect such sources, and what is the observational bias that can be introduced by the choice of the observing strategy when conducting blind surveys of the sky. Different observing strategies are evaluated using simulated light curves and realistic instrument response functions of the Cherenkov Telescope Array (CTA), a future gamma-ray observatory. We show that strategies that makes use of very small observing windows, spread over large periods of time, allows for a faster detection of the source, and are less influenced by the variability properties of the sources, as compared to strategies that concentrate the observing time in a small number of large observing windows. Although derived using CTA as an example, our conclusions are conceptually valid for any IACTs facility, and in general, to all observatories with small field of view and limited duty cycle.

  4. Objective assessment of levels and patterns of physical activity in preschool children

    Brasholt, Martin; Chawes, Bo; Kreiner-Møller, Eskil;

    2013-01-01

    Background:To study in detail levels and patterns of physical activity in preschool children and the effect of gender and body mass index on this activity.Methods:Two hundred and fifty-three children aged 5 years participating in the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC2000......) wore an accelerometer day and night over a 4-weekperiod. The main outcome measure was level of physical activity using the raw data.A secondary measure was time spent in moderate to vigorous physical activity. A Fourier series analysis was applied to study in detail patterns over time...... high body mass index tended to be associated with lower levels of physical activity.Pediatric Research (2013); doi:10.1038/pr.2013.99....

  5. Low-level and high-level modulations of fixational saccades and high frequency oscillatory brain activity in a visual object classification task.

    Kosilo, Maciej; Wuerger, Sophie M; Craddock, Matt; Jennings, Ben J; Hunt, Amelia R; Martinovic, Jasna

    2013-01-01

    Until recently induced gamma-band activity (GBA) was considered a neural marker of cortical object representation. However, induced GBA in the electroencephalogram (EEG) is susceptible to artifacts caused by miniature fixational saccades. Recent studies have demonstrated that fixational saccades also reflect high-level representational processes. Do high-level as opposed to low-level factors influence fixational saccades? What is the effect of these factors on artifact-free GBA? To investigate this, we conducted separate eye tracking and EEG experiments using identical designs. Participants classified line drawings as objects or non-objects. To introduce low-level differences, contours were defined along different directions in cardinal color space: S-cone-isolating, intermediate isoluminant, or a full-color stimulus, the latter containing an additional achromatic component. Prior to the classification task, object discrimination thresholds were measured and stimuli were scaled to matching suprathreshold levels for each participant. In both experiments, behavioral performance was best for full-color stimuli and worst for S-cone isolating stimuli. Saccade rates 200-700 ms after stimulus onset were modulated independently by low and high-level factors, being higher for full-color stimuli than for S-cone isolating stimuli and higher for objects. Low-amplitude evoked GBA and total GBA were observed in very few conditions, showing that paradigms with isoluminant stimuli may not be ideal for eliciting such responses. We conclude that cortical loops involved in the processing of objects are preferentially excited by stimuli that contain achromatic information. Their activation can lead to relatively early exploratory eye movements even for foveally-presented stimuli. PMID:24391611

  6. Low-level and high-level modulations of fixational saccades and high frequency oscillatory brain activity in a visual object classification task

    JasnaMartinovic

    2013-12-01

    Full Text Available Until recently induced gamma-band activity (GBA was considered a neural marker of cortical object representation. However induced GBA in the electroencephalogram (EEG is susceptible to artifacts caused by miniature fixational saccades. Recent studies have demonstrated that fixational saccades also reflect high-level representational processes. Do high-level as opposed to low-level factors influence fixational saccades? What is the effect of these factors on artifact-free GBA? To investigate this, we conducted separate eye tracking and EEG experiments using identical designs. Participants classified line drawings as objects or non-objects. To introduce low-level differences, contours were defined along different directions in cardinal colour space: S-cone-isolating, intermediate isoluminant, or a full-colour stimulus, the latter containing an additional achromatic component. Prior to the classification task, object discrimination thresholds were measured and stimuli were scaled to matching suprathreshold levels for each participant. In both experiments, behavioural performance was best for full-colour stimuli and worst for S-cone isolating stimuli. Saccade rates 200-700 ms after stimulus onset were modulated independently by low and high-level factors, being higher for full-colour stimuli than for S-cone isolating stimuli and higher for objects. Low-amplitude evoked GBA and total GBA were observed in very few conditions, showing that paradigms with isoluminant stimuli may not be ideal for eliciting such responses. We conclude that cortical loops involved in the processing of objects are preferentially excited by stimuli that contain achromatic information. Their activation can lead to relatively early exploratory eye movements even for foveally-presented stimuli.

  7. Application of the Copenhagen Soccer Test in high-level women players - locomotor activities, physiological response and sprint performance

    Bendiksen, Mads; Pettersen, Svein Arne; Ingebrigtsen, Jørgen;

    2013-01-01

    /technical assessments were performed during CSTw for eleven Norwegian high-level women soccer players. The activity pattern during CSTw and CM was monitored using the ZXY tracking system. No differences were observed between CSTw and CM with regards to total distance covered (10093±94 and 9674±191m), high intensity......We evaluated the physiological response, sprint performance and technical ability in various phases of the Copenhagen Soccer Test for Women (CSTw) and investigated whether the locomotor activities of the CSTw were comparable to competitive match-play (CM). Physiological measurements and physical...

  8. An Evaluation of the Correlation between Hepcidin Serum Levels and Disease Activity in Inflammatory Bowel Disease

    Zehra Betül Paköz

    2015-01-01

    Full Text Available Aim. While there are many well-defined serological markers for inflammatory bowel disease (IBD, there is limited evidence that they positively affect clinical outcomes. This study aimed to evaluate the correlation between hepcidin serum levels and disease activity in IBD. Materials and Methods. Eighty-five consecutive IBD patients were enrolled in the study. Hepcidin serum levels were assessed using an enzyme-linked immunosorbent assay (ELISA and were compared with disease activity as well as the interleukin-6 (IL-6 and C-reactive protein (CRP levels. Results. The mean hepcidin serum levels in Crohn’s disease (CD patients in remission and in the active phase were 3837±1436 and 3752±1274 pg/mL, respectively P=0.613. The mean hepcidin serum levels in ulcerative colitis (UC patients in remission and in the active phase were 4285±8623 and 3727±1176 pg/mL, respectively P=0.241. Correlation analysis between inflammatory markers and hepcidin serum levels indicated that there was no correlation between hepcidin levels and IL-6 P=0.582 or CRP P=0.783. Conclusion. As an acute-phase protein, hepcidin seems to have a lower efficacy than other parameters in the detection of activation in IBD.

  9. Light Bridge in a Developing Active Region. I. Observation of Light Bridge and its Dynamic Activity Phenomena

    Toriumi, Shin; Cheung, Mark C M

    2015-01-01

    Light bridges, the bright structures that divide the umbra of sunspots and pores into smaller pieces, are known to produce wide variety of activity events in solar active regions (ARs). It is also known that the light bridges appear in the assembling process of nascent sunspots. The ultimate goal of this series of papers is to reveal the nature of light bridges in developing ARs and the occurrence of activity events associated with the light bridge structures from both observational and numerical approaches. In this first paper, exploiting the observational data obtained by Hinode, IRIS, and Solar Dynamics Observatory (SDO), we investigate the detailed structure of the light bridge in NOAA AR 11974 and its dynamic activity phenomena. As a result, we find that the light bridge has a weak, horizontal magnetic field, which is transported from the interior by large-scale convective upflow and is surrounded by strong, vertical fields of adjacent pores. In the chromosphere above the bridge, a transient brightening ...

  10. Observation of underground water level in the area of forest estate "Sremska Mitrovica " during 2000 and 2001

    Đorović Miroljub

    2002-01-01

    Full Text Available Observation of underground water level in the area of "Jasensko-Belilo", which belongs to the Forest Estate "Sremska Mitrovica", started in 1999. The measurements were performed by means of 2 piezometers set up approximately perpendicularly to the river Sava, forming profile number 1 (Fig.1. The results of these measurements (Fig. 2, 3 show a significant lowering of groundwater level in 2000. The reason is most likely the unfavorable rainfall amount and distribution during that year (Table 2. A much better situation was during 2001 when the minimal groundwater level was up to 2 meters and it was considered to be the result of a favorable amount of rainfall and its distribution during the year (Tables 2, 3. It was noticed that Carpinus betulus appears instead of flowering ash (Fraxinus ornus, which is a good sign that generally the level of underground water is lowering. Also, the phenomenon that pedunculate oak (Quercus robur gradually loses its natural regeneration capability also confirms the trend of lowering underground water level. If this trend continues, oak will be in a very near future naturally substituted by less valuable species, probably Turkey oak (Quercus cerris. If groundwater wells along the river Sava reach the vicinity of this area, which is a plan for the Belgrade city water supply, the trend of groundwater table lowering will be even more expressed and it will certainly endanger the existence of all valuable forest species in this area.

  11. Association between physical activity level and consumption of fruit and vegetables among adolescents in northeast Brazil

    Diego Augusto Santos Silva

    2015-06-01

    Full Text Available OBJECTIVE: To determine the association between low levels of physical activity and consumption of fruits and vegetables among adolescents. METHODS: This cross-sectional study included 2,057 adolescents aged 13 to 18 years from the city of Aracaju, Northeastern Brazil. We analyzed the level of physical activity, consumption of fruits and vegetables by standardized and validated questionnaires. The control variables were sex, age, socioeconomic status, maternal education, alcohol consumption and smoking. For data analysis, univariate and multivariate logistic regression were used, with a significance level of 5%. RESULTS: The prevalence of low levels of physical activity was 81.9%; the inadequate consumption of fruits ocurred in 79.1% and the inadequate consumption of vegetables in 90.6%. Adolescents who consumed few fruits daily had an increase in 40% of chance of being insufficiently active and, for those who consumed few vegetable's the likelihood of being insufficiently active was 50% higher, compared to those who had adequate intake of these foods. CONCLUSIONS: Low levels of physical activity were associated with inadequate fruit and vegetable intake among adolescents in a city in northeastern Brazil. These findings suggest that insufficiently active adolescents have other unhealthy behaviors that may increase the risk of chronic diseases in adulthood.

  12. Long-Term Exposure to High Corticosterone Levels Inducing a Decrease of Adenylate Kinase 1 Activity

    ZHAO Yu'nan; SHEN Jia; SU Hui; HUANG Yufang; XING Dongming; DU Lijun

    2009-01-01

    Corticosterone, a principal glucocorticoid synthesized in the rodent adrenal cortex, can be cumula-tively toxic to hippocampal neurons, the cause of which is not known. The present study determined whether the cytosol adenylate kinase (AK) system was involved in the neuronal damage induced by long-term exposure to high corticosterone levels. We investigated the effects of long-term exposure to high corticosterone levels on AK1 activity, AK1 mRNA expression, and energy levels in cultured hippocampal neurons. The results show that long-term exposure to high corticosterone levels induces a reduction of the cultured hippocampal neuron viability, significantly reduces energy levels, and causes a time-dependant re-duction of the AK1 activity. These findings indicate that changes in the AK system might be the mechanism underlying neuronal damage induced by long-term exposure to high corticosterone levels.

  13. Participation levels of physical activity programs for community-dwelling older adults: A systematic review

    M. Van Der Deijl (Marielle); A. Etman (Astrid); C.B.M. Kamphuis (Carlijn); F.J. van Lenthe (Frank)

    2014-01-01

    textabstractBackground: Although many physical activity (PA) programs have been implemented and tested for effectiveness, high participation levels are needed in order to achieve public health impact. This study aimed to determine participation levels of PA programs aimed to improve PA among communi

  14. Children's Physical Activity Levels during Indoor Recess Dance Videos

    Erwin, Heather; Koufoudakis, Ryann; Beighle, Aaron

    2013-01-01

    Background: Children's physical activity (PA) levels remain low, and schools are being asked to assume a leadership role in PA promotion. Research suggests outdoor recess contributes to children's overall PA levels. However, similar research is not available for indoor recess, which occurs frequently due to a variety of factors. The…

  15. Participatory development activities at local level: case studies in villages of Central Thailand.

    Pongquan, S.

    1992-01-01

    Participatory development activities at local level in a sub-district located in the Central Plain of Thailand were studied employing the theoretical concept of the "linking loops" to analyze the related interactions among target group members and between the local level and superordinated organizat

  16. National level promotion of physical activity: results from England's ACTIVE for LIFE campaign

    Hillsdon, M; Cavill, N; Nanchahal, K.; Diamond, A; White, I.

    2001-01-01

    STUDY OBJECTIVE—To assess the impact of a national campaign on awareness of the campaign, change in knowledge of physical activity recommendations and self reported physical activity.
DESIGN—three year prospective longitudinal survey using a multi-stage, cluster random probability design to select participants.
SETTING—England.
PARTICIPANTS—A nationally representative sample of 3189 adults aged 16-74 years.
MAIN OUTCOME MEASURES—Awareness of the advertising element of the campaign, changes in...

  17. Improving global fire carbon emissions estimates by combining moderate resolution burned area and active fire observations

    Randerson, J. T.; Chen, Y.; Giglio, L.; Rogers, B. M.; van der Werf, G.

    2011-12-01

    In several important biomes, including croplands and tropical forests, many small fires exist that have sizes that are well below the detection limit for the current generation of burned area products derived from moderate resolution spectroradiometers. These fires likely have important effects on greenhouse gas and aerosol emissions and regional air quality. Here we developed an approach for combining 1km thermal anomalies (active fires; MOD14A2) and 500m burned area observations (MCD64A1) to estimate the prevalence of these fires and their likely contribution to burned area and carbon emissions. We first estimated active fires within and outside of 500m burn scars in 0.5 degree grid cells during 2001-2010 for which MCD64A1 burned area observations were available. For these two sets of active fires we then examined mean fire radiative power (FRP) and changes in enhanced vegetation index (EVI) derived from 16-day intervals immediately before and after each active fire observation. To estimate the burned area associated with sub-500m fires, we first applied burned area to active fire ratios derived solely from within burned area perimeters to active fires outside of burn perimeters. In a second step, we further modified our sub-500m burned area estimates using EVI changes from active fires outside and within of burned areas (after subtracting EVI changes derived from control regions). We found that in northern and southern Africa savanna regions and in Central and South America dry forest regions, the number of active fires outside of MCD64A1 burned areas increased considerably towards the end of the fire season. EVI changes for active fires outside of burn perimeters were, on average, considerably smaller than EVI changes associated with active fires inside burn scars, providing evidence for burn scars that were substantially smaller than the 25 ha area of a single 500m pixel. FRP estimates also were lower for active fires outside of burn perimeters. In our

  18. Distribution and activity levels of matrix metalloproteinase 2 and 9 in canine and feline osteosarcoma

    Gebhard, Christiane; Fuchs-Baumgartinger, Andrea; Razzazi-Fazeli, Ebrahim; Miller, Ingrid; Walter, Ingrid

    2016-01-01

    Overexpression of matrix metalloproteinases (MMPs) has been associated with increased tumor aggressiveness and metastasis dissemination. We investigated whether the contrasting metastatic behavior of feline and canine osteosarcoma is related to levels and activities of MMP2 and MMP9. Zymography and immunohistochemistry were used to determine expression levels of MMP2 and MMP9 in canine and feline osteosarcoma. Using immunohistochemistry, increased MMP9 levels were identified in most canine os...

  19. How many days to monitor levels of physical activity in children? A generalizability approach

    MARQUES, A. T.; Maia, José A. R.; Garganta, Rui; Seabra, André; Prista, A.; Bustamante, Alcibíades; Vinagre, J.; Lopes, Vítor P.

    2006-01-01

    There has been some debate about the number of days to monitor physical activity (PA). This discussion is relevant to have reliable estimates (means and variances) of PA of children and adolescents. Still, the approach taken so far, has not dealt with different levels of daily physical activity in children.

  20. Self-Rated Activity Levels and Longevity: Evidence from a 20 Year Longitudinal Study

    Mullee, Mark A.; Coleman, Peter G.; Briggs, Roger S. J.; Stevenson, James E.; Turnbull, Joanne C.

    2008-01-01

    The study reports on factors predicting the longevity of 328 people over the age of 65 drawn from an English city and followed over 20 years. Both the reported activities score and the individual's comparative evaluation of their own level of activity independently reduced the risk of death, even when health and cognitive status were taken into…

  1. Individual and School-Level Socioeconomic Gradients in Physical Activity in Australian School children

    Lewis, Lucy; Maher, Carol; Katzmarzyk, Peter; Olds, Timothy

    2016-01-01

    Background: We attempted to determine whether there was a socioeconomic gradient in 9- to 11-year-old Australian children's moderate-to-vigorous physical activity (MVPA), and whether school facilities or policies supporting physical activity were associated with school-level socioeconomic status (SES) and MVPA. Methods: Children (N = 528) from 26…

  2. Students' Motivation, Physical Activity Levels, & Health-Related Physical Fitness in Middle School Physical Education

    Gao, Zan; Newton, Maria; Carson, Russell L.

    2008-01-01

    This study examines the predictive utility of students' motivation (self-efficacy and task values) to their physical activity levels and health-related physical fitness (cardiovascular fitness and muscular strength/endurance) in middle school fitness activity classes. Participants (N = 305) responded to questionnaires assessing their self-efficacy…

  3. The Strength of Motivation and Physical Activity Level during Leisure Time among Youth in South Korea

    Cho, Min-Haeng

    2004-01-01

    This study was aimed to investigate the relationship between the perceived strength of motivation and level of physical activity during their leisure time of youth. The randomly selected 1,097 (boys = 342, girls = 755) youth reported their duration, frequency, and intensity of physical activity and also indicated their strength of motivation in…

  4. Promoting Higher Level Thinking in Psychology: Is Active Learning the Answer?

    Richmond, Aaron S.; Hagan, Lisa Kindelberger

    2011-01-01

    The goal of this study was to investigate which common instructional methods (active vs. direct) best promote higher level thinking in a psychology course. Over a 5-week period, 71 undergraduates were taught psychology using both active learning and direct instruction. Pre- and post-course assessments were coded as either higher or lower level…

  5. Mol- mutants of Klebsiella pneumoniae requiring high levels of molybdate for nitrogenase activity.

    Imperial, J; Ugalde, R A; Shah, V K; Brill, W J

    1985-01-01

    Mol- mutants of Klebsiella pneumoniae requiring high levels of molybdate for nitrogenase and nitrate reductase activity were characterized. The effects of mol mutations on nitrogenase activity were very similar to those caused by nifQ mutations. Mol- mutants of K. pneumoniae appear to be equivalent to ChlD- mutants of Escherichia coli.

  6. IL-18 Serum Level in Adult Onset Still’s Disease: A Marker of Disease Activity

    Serena Colafrancesco

    2012-01-01

    Conclusions. Higher levels of IL-18 are detected in active AODS patients and correlate with disease activity and inflammatory laboratory features. ROC-AUC analysis of the serum concentration of IL-18 suggests that it can be considered a diagnostic marker of AOSD. This paper supports the targeting of this cytokine as a possible therapeutic option in AOSD.

  7. The Effect of Gambling Activities on Happiness Levels of Nursing Home Residents

    Dixon, Mark R.; Nastally, Becky L.; Waterman, Amber

    2010-01-01

    The current study evaluated the effect of participating in simulated gambling activities on happiness levels of 3 nursing home residents. A 4-component analysis was used to measure objective responses associated with happiness during baseline, varying durations of engagement in simulated gambling activities, and 2 follow-up periods. Results…

  8. Observation of acoustic-gravity waves in the upper atmosphere during severe storm activity

    Hung, R. J.

    1975-01-01

    A nine-element continuum wave spectrum, high-frequency, Doppler sounder array has been used to detect upper atmospheric wave-like disturbances during periods with severe weather activity, particularly severe thunderstorms and tornadoes. Five events of severe weather activity, including extreme tornado outbreak of April 3, 1974, were chosen for the present study. The analysis of Doppler records shows that both infrasonic waves and gravity waves were excited when severe storms appeared in the north Alabama area. Primarily, in the case of tornado activity, S-shaped Doppler fluctuations or Doppler fold-backs are observed, while quasi-sinusoidal fluctuations are more common in the case of thunderstorm activity. A criterion for the production of Doppler fold-backs is derived and compared with possible tornado conditions.

  9. Topoisomerase I as a Biomarker: Detection of Activity at the Single Molecule Level

    Proszek, Joanna; Roy, Amit; Jakobsen, Ann-Katrine;

    2014-01-01

    hTopI have been reported to result in CPT resistance. Therefore, hTOPI gene copy number, mRNA level, protein amount, and enzyme activity have been studied to explain differences in cellular response to CPT. We show that Rolling Circle Enhanced Enzyme Activity Detection (REEAD), allowing measurement...... of hTopI cleavage-religation activity at the single molecule level, may be used to detect posttranslational enzymatic differences influencing CPT response. These differences cannot be detected by analysis of hTopI gene copy number, mRNA amount, or protein amount, and only become apparent upon...... measuring the activity of hTopI in the presence of CPT. Furthermore, we detected differences in the activity of the repair enzyme tyrosyl-DNA phosphodiesterase 1, which is involved in repair of hTopI-induced DNA damage. Since increased TDP1 activity can reduce cellular CPT sensitivity we suggest that a...

  10. Elevated homocysteine levels in suction-induced blister fluid of active vitiligo lesions.

    Anbar, Tag; Zuel-Fakkar, Nehal Mohamed; Matta, Mary Fikry; Arbab, Mai Mohammed Ibrahim

    2016-02-01

    Vitiligo is the most prevalent acquired pigmentary disorder as a result of destruction of melanocytes. Several studies have reported increased serum levels of homocysteine (Hcy) in vitiligo patients which may be the result of decreased Vitamin B12 and folic acid levels. In addition, homocystinuria is associated with pigmentary dilution. On the other hand, other studies reported normal serum homocysteine levels. Our aim was to study the Hcy level in active vitiligo patients both in serum and in suction blister fluid obtained from the lesional skin. A total of 30 patients with active vitiligo of both sexes and 30 healthy volunteers were enrolled in this study. Sera from the blood and from lesional induced bullae were obtained from the patients and controls and were assayed for Hcy by enzyme-linked immunosorbent assay (ELISA). The collected data were analyzed by SPSS version 17. There were no significant differences in the serum levels of Hcy between patients and healthy controls, however, the increase in Hcy level was highly statistically significant in the patients' lesional induced bulla compared to the healthy controls. There was no significant difference in Hcy levels between males and females and between patients with negative or positive family histories of vitiligo. The presence of a high homocysteine level in active vitiligo lesions points to a local event occurring in this lesion, which is not reflected as an increase in the patient's serum level. PMID:26678812

  11. Towards Observational Astronomy of Jets in Active Galaxies from General Relativistic Magnetohydrodynamic Simulations

    Anantua, Richard; Roger Blandford, Jonathan McKinney and Alexander Tchekhovskoy

    2016-01-01

    We carry out the process of "observing" simulations of active galactic nuclei (AGN) with relativistic jets (hereafter called jet/accretion disk/black hole (JAB) systems) from ray tracing between image plane and source to convolving the resulting images with a point spread function. Images are generated at arbitrary observer angle relative to the black hole spin axis by implementing spatial and temporal interpolation of conserved magnetohydrodynamic flow quantities from a time series of output datablocks from fully general relativistic 3D simulations. We also describe the evolution of simulations of JAB systems' dynamical and kinematic variables, e.g., velocity shear and momentum density, respectively, and the variation of these variables with respect to observer polar and azimuthal angles. We produce, at frequencies from radio to optical, fixed observer time intensity and polarization maps using various plasma physics motivated prescriptions for the emissivity function of physical quantities from the simulation output, and analyze the corresponding light curves. Our hypothesis is that this approach reproduces observed features of JAB systems such as superluminal bulk flow projections and quasi-periodic oscillations in the light curves more closely than extant stylized analytical models, e.g., cannonball bulk flows. Moreover, our development of user-friendly, versatile C++ routines for processing images of state-of-the-art simulations of JAB systems may afford greater flexibility for observing a wide range of sources from high power BL-Lacs to low power quasars (possibly with the same simulation) without requiring years of observation using multiple telescopes. Advantages of observing simulations instead of observing astrophysical sources directly include: the absence of a diffraction limit, panoramic views of the same object and the ability to freely track features. Light travel time effects become significant for high Lorentz factor and small angles between

  12. The influence of self-rated health on the development of change in the level of physical activity for participants in prescribed exercise

    Bredahl, Thomas Viskum Gjelstrup; Singhammer, John

    2011-01-01

    self-rated health will improve their level of physical activity to a clinical relevant level in the long term, if they manage to stay compliant during the observation period. An assessment of good and poor self-rated health supplemented by a discussion of psychical and physical domains of self...

  13. A College-Level Inquiry-Based Laboratory Activity on Transiting Planets

    McConnell, Nicholas J.; Medling, Anne M.; Strubbe, Linda E.; Moth, Pimol; Montgomery, Ryan M.; Raschke, Lynne M.; Hunter, Lisa; Goza, Barbara

    2010-01-01

    We have designed an inquiry-based laboratory activity on transiting extrasolar planets for an introductory college-level astronomy class. The activity was designed with the intent of simultaneously teaching science process skills and factual content about transits and light curves. In the activity, groups of two to four students each formulate a specific science question and design and carry out an investigation using a table-top model of a star and orbiting planet. Each group then presents t...

  14. Comparison of pre- and post-intervention levels of physical activity among sedentary Finnish mothers

    Green, Weldon T; Novoradovskaya, Elizaveta

    2010-01-01

    Weldon T. Green and Elizaveta Novoradovskaya, 2012. Comparison of pre- and post-intervention levels of physical activity among sedentary Finnish mothers. Master’s Thesis in Sport and Department of Sport Sciences. University of Jyvaskyla. 39 p. The 1990’s marked a shift in the academic understanding of health-enhancing physical activity that was different from the exercise-based physical fitness paradigm that ruled public health policy at the time. Since then, lifestyle physical activity ...

  15. Cortical activity prior to, and during, observation and execution of sequential finger movements.

    Calmels, Claire; Holmes, Paul; Jarry, Gilbert; Lévèque, Jean-Michel; Hars, Magaly; Stam, Cornelis J

    2006-01-01

    The aim of this study was to provide further evidence for the existence of a mirror neuron system in humans using electroencephalography during the observation and execution of non-object-related movements. Event-related desynchronization and synchronization (ERD/ERS) were used to characterize brain activity prior to, and during, observation and execution of a finger movement in four frequency bands (7-10 Hz, 10-13 Hz, 13-20 Hz, and 20-30 Hz). Electroencephalograms (EEGs) were recorded from 19 electrode sites in eight participants. In all the frequency bands and electrode sites, results revealed that there was no significant differences in EEG cortical activity between the observation condition and the execution conditions. Comparison of the two stages of the movement (i.e., pre-movement and movement) in the observation and execution conditions showed, in most cases, that pre-movement ERD values were less than movement ERD values. Whilst there was not an identical match of EEG cortical indices, this study provides further support for the existence of a mirror neuron system in humans. The incomplete congruence may be explained by the different behaviors, the nature of the task and factors in the observed action coded by the mirror system. PMID:17136468

  16. Does Spinal Fusion and Scoliosis Correction Improve Activity and Participation for Children With GMFCS level 4 and 5 Cerebral Palsy?

    Sewell, Mathew David; Wallace, Charlie; Malagelada, Francesc; Gibson, Alex; Noordeen, Hilali; Tucker, Stewart; Molloy, Sean; Lehovsky, Jan

    2015-12-01

    Spinal fusion is used to treat scoliosis in children with cerebral palsy (CP). Following intervention, the WHO considers activity and participation should be assessed to guide intervention and assess the effects. This study assesses whether spinal fusion for scoliosis improves activity and participation for children with severe CP.Retrospective cohort study of 70 children (39M:31F) with GMFCS level 4/5 CP and significant scoliosis. Thirty-six underwent observational and/or brace treatment as the sole treatment for their scoliosis, and 34 underwent surgery. Children in the operative group were older and had worse scoliosis than those in the observational group. Questionnaire and radiographic data were recorded over a 2-year period. The ASKp was used to measure activity and participation.In the observational group, Cobb angle and pelvic obliquity increased from 51 (40-90) and 10 (0-30) to 70 (43-111) and 14 (0-37). Mean ASKp decreased from 16.3 (1-38) to 14.2 (1-36). In the operative group, Cobb angle and pelvic obliquity decreased from 81 (50-131) and 14 (1-35) to 38 (10-76) and 9 (0-24). Mean ASKp increased from 10.5 (0-29) to 15.9 (3-38). Spinal-related pain correlated most with change in activity and participation in both groups. There was no difference in mobility, GMFCS level, feeding or communication in either group before and after treatment.In children with significant scoliosis and CP classified within GMFCS levels 4 and 5, spinal fusion was associated with an improvement in activity and participation, whereas nonoperative treatment was associated with a small reduction. Pain should be carefully assessed to guide intervention. PMID:26656322

  17. Limits to Quantum Gravity Effects from Observations of TeV Flares in Active Galaxies

    Biller, S. D.; Breslin, A. C.; Buckley, J.; Catanese, M.; Carson, M.; Carter-Lewis, D. A.; Cawley, M. F.; Fegan, D. J.; Finley, J.; Gaidos, J. A.; Hillas, A.M.; Krennrich, F.; Lamb, R. C.; Lessard, R.; Masterson, C.

    1998-01-01

    We have used data from the TeV gamma-ray flare associated with the active galaxy Markarian 421 observed on 15 May 1996 to place bounds on the possible energy-dependence of the speed of light in the context of an effective quantum gravitational energy scale. The possibility of an observable time dispersion in high energy radiation has recently received attention in the literature, with some suggestions that the relevant energy scale could be less than the Planck mass and perhaps as low as 10^1...

  18. Combined X-Ray and mm-Wave Observations of Radio Quiet Active Galaxies

    Behar, E.

    2016-06-01

    A connection between the X-ray and radio sources in radio quiet active galaxies (AGNs) will be demonstrated. High radio frequency, i.e., mm-wave observations are promising probes of the X-ray emitting inner regions of the accretion disks in radio quiet AGNs. An argument for simultaneous observations in X-rays and in mm waves will be made, in order to promote these as one of the future science goals of X-ray and AGN astronomy in the next decade. Preliminary results from an exploratory campaign with several space and ground based telescopes will be presented.

  19. Low levels of physical activity in patients with severe mental illness

    Nyboe, Lene; Lund, H

    2013-01-01

    Background: Physical inactivity is an independent risk factor for cardiovascular diseases and Type 2 diabetes, both being highly prevalent in patients with severe mental illness. Though physical activity has become an important issue in psychiatric treatment and rehabilitation in the past decade......, systematic evaluations of physical activity level in psychiatric populations could be more disseminated. Aim: The primary aim of the study was to investigate the physical activity level of psychiatric patients in comparison with healthy controls. Methods: Patients with severe mental illness (n =47) and a...

  20. Evidence that elevated CO2 levels can indirectly increase rhizosphere denitrifier activity

    Smart, D. R.; Ritchie, K.; Stark, J. M.; Bugbee, B.

    1997-01-01

    We examined the influence of elevated CO2 concentration on denitrifier enzyme activity in wheat rhizoplanes by using controlled environments and solution culture techniques. Potential denitrification activity was from 3 to 24 times higher on roots that were grown under an elevated CO2 concentration of 1,000 micromoles of CO2 mol-1 than on roots grown under ambient levels of CO2. Nitrogen loss, as determined by a nitrogen mass balance, increased with elevated CO2 levels in the shoot environment and with a high NO3- concentration in the rooting zone. These results indicated that aerial CO2 concentration can play a role in rhizosphere denitrifier activity.

  1. Year ahead prediction of US landfalling hurricane numbers: the optimal combination of multiple levels of activity since 1900

    Binter, R; Khare, S; O'Shay, A; Penzer, J; Binter, Roman; Jewson, Stephen; Khare, Shree; Shay, Adam O'; Penzer, Jeremy

    2006-01-01

    In earlier work we considered methods for predicting future levels of hurricane activity based on the assumption that historical mean activity was at one constant level from 1900 to 1994, and has been at another constant level since then. We now make this model a little more subtle, and account for the possibility of four different levels of mean hurricane activity since 1900.

  2. Changes in the scheduling process according to observed activity- travel flexibility

    Garcia-Jiménez, María Elena; Ruiz Sánchez, Tomás; Mars, Lidón; GARCÍA GARCÉS, PABLO

    2014-01-01

    In this work we analyze the reasons for changing pre-planned activities and travels episodes considering the type of modification observed during the scheduling process. Specifically we selected a small sample from those pre-planned episodes that are no executed at all as a pilot study. The data analyzed was collected in the first wave of a weekly activity-travel panel survey carried out in Valencia (Spain) in 2010. Each survey wave consisted on a face-to-face interview to generate a pre-plan...

  3. FDG-PET imaging of lower extremity muscular activity during level walking

    We analyzed muscular activity of the lower extremities during level walking using positron emission tomography (PET) with 18F-fluorodeoxyglucose (18F-FDG). We examined 17 healthy male subjects; 11 were assigned to a walking group and 6 to a resting group. After 18F-FDG injection, the walking group subjects walked at a free speed for 15 min. A whole-body image was then obtained by a PET camera, and the standardized uptake ratio (SUR) was computed for each muscle. The SUR for each muscle of the walking group was compared with that for the corresponding muscles in the resting group. The level of muscular activity of all the muscles we examined were higher during level walking than when resting. The activity of the lower leg muscles was higher than that of the thigh muscles during level walking. The muscular activity of the soleus was highest among all the muscles examined. Among the gluteal muscles, the muscular activity of the gluteus minimus was higher than that of the gluteus maximus and gluteus medius. The concurrent validity of measuring muscular activity of the lower extremity during level walking by the PET method using 18F-FDG was demonstrated. (author)

  4. Activity of Proteolytic Enzymes and Level of Cystatin C in the Peripartum Period.

    Cyganek, Anna; Wyczalkowska-Tomasik, Aleksandra; Jarmuzek, Patrycja; Grzechocinska, Barbara; Jabiry-Zieniewicz, Zoulikha; Paczek, Leszek; Wielgos, Miroslaw

    2016-01-01

    Objectives. The aim of the study was to evaluate the activity of cathepsin B, collagenases, trypsin, and plasmin and concentration of cystatin C in serum of healthy pregnant women in peripartum period. Study Design. The study group included 45 women in uncomplicated pregnancies. Blood samples were collected in four time points. Enzyme activity was measured by spectrofluorometric method. The level of cystatin C was measured using immunonephelometric method. Results. Mean activity of cathepsin B and the level of serum cystatin C were significantly higher in the study group. Collagenase activity was significantly lower in the study group than the control group. No differences in collagenase, plasmin, and trypsin activity on each day of the peripartum period were found. Conclusion. High activity of cathepsin B and increased level of cystatin C are typical for women in late pregnancy. Those levels significantly decrease after delivery which can be associated with potential role of those markers in placental separation. The insignificant changes of cystatin C level in the peripartum period seem to exclude the possibility of using cystatin C as a marker for renal insufficiency in the peripartum period but additional research is necessary to investigate the matter further. PMID:26904684

  5. Project Seavolc: sea-level change and the stability and activity of coastal and island volcanoes

    McGuire, W.J. [Cheltenham and Gloucester College of Higher Education, Cheltenham (United Kingdom)

    1994-12-31

    The entire eastern flank of Mount Etna has been unstable for much of its history, demonstrating seaward slumping of a 30 km wide segment of the edifice which borders the Ionian Sea. Project Seabolc aims to better constrain the temporaral history of instability and slope movement, and to correlate this behaviour with both sea-level change and eruptive activity during the late Quaternary. Results from the Etna study, together with evidence from volcanoes in the Canary Islands, Aeolian Islands, and Bay of Naples, will enable us to test a model relating slope instability and eruptive activity at coastal and island volcanoes, to the repeatedly changing sea levels which characterized the Quaternary. The disposition of tectonic plates constrains the locations of most volcanoes to marine settings or to adjacent continental margins, leading to their being strongly susceptible either to the direct effects of changing sea levels (e.g. edifice erosion or debuttressing) or to general crustal loading and unloading caused by changing ocean volumes. Temporal distribution of tephra horizons in eastern Mediterranean sediments supports a correlation between episodes of rising and falling sea level, and increased levels of explosive volcanic activity, which we attribute to the dynamic response of volcanic edifices to a wide range of primary and secondary effects induced by variations in sea level. Implications of the proposed model for climate change are profound and important, with explosive volcanic activity triggered by changing sea levels having the potential to modulate the Quaternary global temperature profile. 24 refs., 3 figs.

  6. Determination of no-observed effect level (NOEL-biomarker equivalents to interpret biomonitoring data for organophosphorus pesticides in children

    Bouchard Michèle

    2009-02-01

    Full Text Available Abstract Background Environmental exposure to organophosphorus pesticides has been characterized in various populations, but interpretation of these data from a health risk perspective remains an issue. The current paper proposes biological reference values to help interpret biomonitoring data related to an exposure to organophosphorus pesticides in children for which measurements of alkylphosphate metabolites are available. Methods Published models describing the kinetics of malathion and chlorpyrifos in humans were used to determine no-observed effect level – biomarker equivalents for methylphosphates and ethylphosphates, respectively. These were expressed in the form of cumulative urinary amounts of alkylphosphates over specified time periods corresponding to an absorbed no-observed effect level dose (derived from a published human exposure dose and assuming various plausible exposure scenarios. Cumulative amounts of methylphosphate and ethylphosphate metabolites measured in the urine of a group of Quebec children were then compared to the proposed biological reference values. Results From a published no-observed effect level dose for malathion and chlorpyrifos, the model predicts corresponding oral biological reference values for methylphosphate and ethylphosphate derivatives of 106 and 52 nmol/kg of body weight, respectively, in 12-h nighttime urine collections, and dermal biological reference values of 40 and 32 nmol/kg of body weight. Out of the 442 available urine samples, only one presented a methylphosphate excretion exceeding the biological reference value established on the basis of a dermal exposure scenario and none of the methylphosphate and ethylphosphate excretion values were above the obtained oral biological reference values, which reflect the main exposure route in children. Conclusion This study is a first step towards the development of biological guidelines for organophophorus pesticides using a toxicokinetic modeling

  7. THE RELATION BETWEEN PHAGOCYTIC ACTIVITY OF THE NEUTROPHILS (PMN AND THE GLICEMIC LEVEL AT THE SPORTSMAN

    D. Cotuna

    1999-01-01

    Full Text Available We tried to find a relation between the phagocytes activity of the neutrophils and the level of glicemy in athletes applying the ANOVA test, taking into account the fact that hyperglicemy reduces the phagocytes activity of the neutrophils which becomes so more spherical and burden after the contact with foreign particles. The phagocyte activity of neutrophils (PMN had been established through NBT technique and the glicemy level was determined by Hagerdon – Jansen method. From these notices processed by ANOVA test applied on the values of phagocyte activity of PMN and on glicemy level we conclude that does not exist a tendency of association of these two parameters in a relationship.

  8. Levels of occupational stress and stressful activities for nurses working in emergency

    José Ricardo Ferreira da Fonseca

    2014-12-01

    Full Text Available The study aimed to identify stress levels, areas and their activities identified as stressful by nurses working in the emergence in Manaus, AM, Brazil. It is an epidemiological, cross-sectional design, with 36 emergency nurses from December 2010 to January 2011. The Bianchi Stress Scale with 57 questions was used. The nurses were at risk for high levels of stress. The most stressful areas were the operation of the unit, conditions of work and personnel administration, and the most stressful activity was the request for equipment review and repair. The difference by Friedman test between the areas was significant (p <0.05, Dunn post-test significant (p <0.05 when compared by peers. The accumulation of management activities with the assistance activities can generate higher levels of stress, it is necessary to invest in improving the work environment and management support to minimize the stress experienced at work.

  9. New levels and transitions in 72Ge observed in the 72As(β++EC)72Ge decay

    The decay of 72As has been investigated by means of γ-ray spectroscopy. The 72As nuclei were produced through the 72Ge(p, n)72As reaction. The Compton-suppressed spectrometer and high-purity Ge detectors have been used in singles and in coincidence modes respectively to study γ-rays in the β++EC decay of 72As to 72Ge. 79 γ-rays, among which 3 were observed for the first time, were reported. A decay scheme of 72As including 1 new level is proposed that accommodates 77 of these transitions. Tentative spin and parity assignments are suggested for a number of levels according to the log ft values and γ-branching ratios. (author)

  10. Muonated cyclohexadienyl radicals observed by level crossing resonance in dilute solutions of benzene in hexane subjected to muon-irradiation

    Benzene is used here as a scavenger of muonium to produce the muonated cyclohexadienyl radical in dilute solutions in n-hexane. The radical was identified by level crossing resonance spectroscopy (LFR) by observing the proton resonance of the -CHMu group occurring at 2.059T. Its yield is found to equal the sum of the muonium atom yield and the ''missing'' muon yield in hexane (total 35% of the incident muons). Consequently, the complete dispersement of muons in different chemical associations is now accounted for in a saturated hydrocarbon liquid, and is seen to be similar to that in water. (author)

  11. Muonated cyclohexadienyl radicals observed by level crossing resonance in dilute solutions of benzene in hexane subjected to muon-irradiation

    Benzene is used here as a scavenger of muonium to produce the muonated cyclohexadienyl radical in dilute solutions in n-hexane. The radical was identified by level crossing resonance spectroscopy (LCR) by observing the proton resonance of the -CHMu group occurring at 2.059T. Its yield is found to equal the sum of the muonium atom yield and the 'missing' muon yield in hexane (total 35% of the incident muons). Consequently, the complete dispersement of muons in different chemical associations is now accounted for in a saturated hydrocarbon liquid, and is seen to be similar to that in water

  12. Induction of antioxidant enzyme activity and lipid peroxidation level in ion-beam-bombarded rice seeds

    Highlights: ► Ion beam bombarded rice seeds in vacuum. ► Studied seed survival from the ion bombardment. ► Determined various antioxidant enzyme activities and lipid peroxidation level. ► Discussed vacuum, ion species and ion energy effects. ► Attributed the changes to free radical formation due to ion bombardment. -- Abstract: Low-energy ion beam bombardment has been used to mutate a wide variety of plant species. To explore the indirect effects of low-energy ion beam on biological damage due to the free radical production in plant cells, the increase in antioxidant enzyme activities and lipid peroxidation level was investigated in ion-bombarded rice seeds. Local rice seeds were bombarded with nitrogen or argon ion beams at energies of 29–60 keV and ion fluences of 1 × 1016 ions cm−2. The activities of the antioxidant enzymes; superoxide dismutase (SOD), catalase (CAT), ascorbate peroxidase (APX), dehydroascorbate reductase (DHAR), glutathione reductase (GR), glutathione S-transferase (GST) and lipid peroxidation level were assayed in the germinated rice seeds after ion bombardment. The results showed most of the enzyme activities and lipid peroxidation levels in both the argon and nitrogen bombarded samples were higher than those in the natural control. N-ion bombardment could induce higher levels of antioxidant enzyme activities in the rice samples than the Ar-ion bombardment. Additional effects due to the vacuum condition were found to affect activities of some antioxidant enzymes and lipid peroxidation level. This study demonstrates that ion beam bombardment and vacuum condition could induce the antioxidant enzyme activity and lipid peroxidation level which might be due to free radical production in the bombarded rice seeds

  13. Induction of antioxidant enzyme activity and lipid peroxidation level in ion-beam-bombarded rice seeds

    Semsang, Nuananong, E-mail: nsemsang@gmail.com [Molecular Biology Laboratory, Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Yu, LiangDeng [Plasma and Beam Physics Research Facility, Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200 (Thailand); Thailand Center of Excellence in Physics, Commission on Higher Education, 328 Si Ayutthaya Road, Bangkok 10400 (Thailand)

    2013-07-15

    Highlights: ► Ion beam bombarded rice seeds in vacuum. ► Studied seed survival from the ion bombardment. ► Determined various antioxidant enzyme activities and lipid peroxidation level. ► Discussed vacuum, ion species and ion energy effects. ► Attributed the changes to free radical formation due to ion bombardment. -- Abstract: Low-energy ion beam bombardment has been used to mutate a wide variety of plant species. To explore the indirect effects of low-energy ion beam on biological damage due to the free radical production in plant cells, the increase in antioxidant enzyme activities and lipid peroxidation level was investigated in ion-bombarded rice seeds. Local rice seeds were bombarded with nitrogen or argon ion beams at energies of 29–60 keV and ion fluences of 1 × 10{sup 16} ions cm{sup −2}. The activities of the antioxidant enzymes; superoxide dismutase (SOD), catalase (CAT), ascorbate peroxidase (APX), dehydroascorbate reductase (DHAR), glutathione reductase (GR), glutathione S-transferase (GST) and lipid peroxidation level were assayed in the germinated rice seeds after ion bombardment. The results showed most of the enzyme activities and lipid peroxidation levels in both the argon and nitrogen bombarded samples were higher than those in the natural control. N-ion bombardment could induce higher levels of antioxidant enzyme activities in the rice samples than the Ar-ion bombardment. Additional effects due to the vacuum condition were found to affect activities of some antioxidant enzymes and lipid peroxidation level. This study demonstrates that ion beam bombardment and vacuum condition could induce the antioxidant enzyme activity and lipid peroxidation level which might be due to free radical production in the bombarded rice seeds.

  14. Do enhancements to the urban built environment improve physical activity levels among socially disadvantaged populations?

    Maddison Ralph

    2011-07-01

    Full Text Available Abstract Background There is growing recognition that the urban built environment influences physical activity at the population level, although the effects on disadvantaged groups are less well understood. Using the examples of open/green space and street connectivity, this paper explores whether enhancements to the built environment have potential for addressing physical activity-related health inequalities among Māori, Pacific and low income communities in New Zealand. Method A high-level review of the international literature relating open space and street connectivity to physical activity and/or related health outcomes at a population level was completed. Consideration was given to whether these features of the built environment have a disproportionate effect on disadvantaged populations. Results Findings from international studies suggest that open space and street connectivity have a beneficial effect on physical activity. Enhancing the built environment may be particularly advantageous for improving physical activity levels among disadvantaged populations. Conclusion It is likely that open space and street connectivity have a positive effect on physical activity behaviour; however due to the cross-sectional nature of existing research and the paucity of research among disadvantaged populations definitive conclusions about the effect in these populations cannot be made. Further research is required (e.g. natural experiments or quasi experimental research designs to determine the effect of changing the environment on physical activity and obesity.

  15. A Rapidly Evolving Active Region NOAA 8032 observed on April 15th, 1997

    Shibu K. Mathew; Ashok Ambastha

    2000-09-01

    The active region NOAA 8032 of April 15, 1997 was observed to evolve rapidly. The GOES X-ray data showed a number of sub-flares and two C-class flares during the 8-9 hours of its evolution. The magnetic evolution of this region is studied to ascertain its role in flare production. Large changes were observed in magnetic field configuration due to the emergence of new magnetic flux regions (EFR). Most of the new emergence occured very close to the existing magnetic regions, which resulted in strong magnetic field gradients in this region. EFR driven reconnection of the field lines and subsequent flux cancellation might be the reason for the continuous occurrence of sub-flares and other related activities.

  16. Midwinter suppression of baroclinic storm activity on Mars: observations and models

    P. L. Read; Mulholland, D. P.; Montabone, L.; Lewis, S R

    2011-01-01

    We present results from assimilated analyses of observations from the Mars Global Surveyor Thermal Emission Spectrometer showing evidence for a regular suppression of baroclinic circumpolar storm activity in both hemispheres of Mars around winter solstice. General circulation model simulations are then used to elucidate the structure and possible causes of this suppression, for which the local ‘Eady growth rate’ appears to be a good predictor.

  17. A transient increase in total head phosphotyrosine levels is observed upon the emergence of Aedes aegypti from the pupal stage

    Willy Jablonka

    2011-08-01

    Full Text Available Phosphorylation and dephosphorylation of protein tyrosine residues constitutes a major biochemical regulatory mechanism for the cell. We report a transient increase in the total tyrosine phosphorylation of the Aedes aegypti head during the first days after emergence from the pupal stage. This correlates with an initial reduction in total head protein tyrosine phosphatase (PTP activity. Similarly, phosphotyrosine (pTyr-containing bands are seen in extracts prepared from both male and female heads and are spread among a variety of structures including the antennae, proboscis and the maxillary palps combined with the proboscis. Also, mosquitoes treated with sodium orthovanadate, a classical PTP inhibitor, show reduced blood-feeding activity and higher head tyrosine phosphorylation levels. These results suggest that pTyr-mediated signalling pathways may play a role in the initial days following the emergence of the adult mosquito from the pupal stage.

  18. Is the low level of physical activity a public policy issue?

    Kalman Michal

    2013-03-01

    Full Text Available BACKGROUND: Many studies and scientific evidence confirm a positive effect of physical activity on the quality of life and human health. Physical activity, which is also one of the key factors preventing mass non-communicable diseases, is decreasing in Europe, including the Czech Republic, both in children and adults. Serious health consequences for the population and economy of the countries are a reason for a discussion about including the low level of physical activity among public policy issues and a higher allocation of public sources into the area of physical activity promotion. OBJECTIVES: The main objective of the paper is to determine whether the low level of physical activity is a public policy issue. An issue that should by systematically addressed by national, regional as well as local policy. METHODS: Through the policy analysis approach we conducted a content analysis of 25 systematically selected foreign national strategies aimed at the issue of physical activity promotion. The data source was an internal database of the World Health Organization - the International Inventory of Documents on Physical Activity Promotion. The content analysis of the strategies was performed using the Atlas.ti software tool. RESULTS: During a content analysis of 25 foreign strategies a total of 411 text segments (quotations relating to the low level of physical activity were selected. These text segments showed five basic features of a public policy issue according to a conceptual framework developed by Bardach (2000 and Patton and Sawicky (1993 - 1 affects the lives of a significant number of people of a society; 2 is analysable; 3 can be solved through public policy tools; 4 the primary cause or problem can be defined; 5 cannot be solved easily and quickly. CONCLUSIONS: The results indicate that the low level of physical activity is a public policy issue that must be systematically addressed at national level.

  19. Using the EXIST Active Shields for Earth Occultation Observations of X-Ray Sources

    Wilson, Colleen A.; Fishman, Gerald; Hong, Jae-Sub; Gridlay, Jonathan; Krawczynski, Henric

    2005-01-01

    The EXIST active shields, now being planned for the main detectors of the coded aperture telescope, will have approximately 15 times the area of the BATSE detectors; and they will have a good geometry on the spacecraft for viewing both the leading and training Earth's limb for occultation observations. These occultation observations will complement the imaging observations of EXIST and can extend them to higher energies. Earth occultatio observations of the hard X-ray sky with BATSE on the Compton Gamma Ray Observatory developed and demonstrated the capabilities of large, flat, uncollimated detectors for this method. With BATSE, a catalog of 179 X-ray sources was monitored twice every spacecraft orbit for 9 years at energies above about 25 keV, resulting in 83 definite detections and 36 possible detections with 5-sigma detection sensitivities of 3.5-20 mcrab (20-430 keV) depending on the sky location. This catalog included four transients discovered with this technique and many variable objects (galactic and extragalactic). This poster will describe the Earth occultation technique, summarize the BATSE occultation observations, and compare the basic observational parameters of the occultation detector elements of BATSE and EXIST.

  20. Observing ground surface change series at active volcanoes in Indonesia using backscattering intensity of SAR data

    Saepuloh, Asep; Trianaputri, Mila Olivia

    2015-04-01

    Indonesia contains 27 active volcanoes passing the West through the East part. Therefore, Indonesia is the most hazard front due to the volcanic activities. To obtain the new precursory signals leading to the eruptions, we applied remote sensing technique to observe ground surface change series at the summit of Sinabung and Kelud volcanoes. Sinabung volcano is located at Karo Region, North Sumatra Province. This volcano is a strato volcano type which is re-activated in August 2010. The eruption continues to the later years by ejecting volcanic products such as lava, pyroclastic flow, and ash fall deposits. This study is targeted to observe ground surface change series at the summit of Sinabung volcano since 2007 to 2011. In addition, we also compared the summit ground surface changes after the eruptions of Kelud volcano in 2007. Kelud volcano is also strato volcano type which is located at East Java, Indonesia. The Synthetic Aperture Radar (SAR) remotely sensed technology makes possible to observe rapidly a wide ground surface changes related to ground surface roughness. Detection series were performed by extracting the backscattering intensity of the Phased Array type L-band Synthetic Aperture Radar (PALSAR) onboard the Advanced Land Observing Satellite (ALOS). The intensity values were then calculated using a Normalized Radar Cross-Section (NRCS). Based on surface roughness criterion at the summit of Sinabung volcano, we could observe the ground surface changes prior to the early eruption in August 2010. The continuous increment of NRCS values showed clearly at window size 3×3 pixel of the summit of Sinabung volcano. The same phenomenon was also detected at the summit of Kelud volcano after the 2007 eruptions. The detected ground surface changes were validated using optical Landsat-8, backscattering intensity ratio for volcanic products detection, and radial component of a tilt-meter data.

  1. Trapezius muscle activity increases during near work activity regardless of accommodation/vergence demand level

    Richter, H. O.; Zetterberg, Camilla; Forsman, M

    2015-01-01

    Aim To investigate if trapezius muscle activity increases over time during visually demanding near work. Methods The vision task consisted of sustained focusing on a contrast-varying black and white Gabor grating. Sixty-six participants with a median age of 38 (range 19–47) fixated the grating from a distance of 65 cm (1.5 D) during four counterbalanced 7-min periods: binocularly through −3.5 D lenses, and monocularly through −3.5 D, 0 D and +3.5 D. Accommodation, heart rate variability and t...

  2. Electromyography Activation Levels of the 3 Gluteus Medius Subdivisions During Manual Strength Testing

    Otten, Roald; Tol, Johannes L; Holmich, Per;

    2015-01-01

    deficits and guide specific rehabilitation programs. However, the optimal positions for assessing the strength and activation of these subdivisions are unknown. OBJECTIVE: The first aim was to establish which strength-testing positions produce the highest surface electromyography (sEMG) activation levels...... of the individual GM subdivisions. The second aim was to evaluate differences in sEMG activation levels between the tested and contralateral (stabilizing) leg. METHOD: Twenty healthy physically active male subjects participated in this study. Muscle activity using sEMG was recorded for the GM...... subdivisions (P < .01). The posterior GM subdivision showed no significant difference (P = .154). CONCLUSION: Side-lying in neutral and side-lying with hip internal rotation are the 2 positions recommended to evaluate GM function and guide specific GM rehabilitation....

  3. Multimodel-based power-level control with state-feedback and observer for load-follow PWR core

    Highlights: • The equilibrium manifold and nonlinearity measure of the core are proposed. • The linear multi-model of the core is built based on the core nonlinearity measure. • A new state feedback control is used to design local controllers of the core. • Flexibility partitioning of model and control is presented for the nonlinear core. • The global stability of the core load follow control is analyzed. - Abstract: The purpose of this investigation is that a nonlinear Pressurized Water Reactor (PWR) core load following control system is designed and the global stability of the system is analyzed theoretically. On the basis of modeling a nonlinear PWR core and proposing the equilibrium manifold and the nonlinearity measure of the core to calculate the distribution situation of the core nonlinearity measure in the entire range of power level, linearized models of the core at five power levels are chosen as local models of the core and the set of local models is used to substitute the nonlinear core model. The full-state feedback control with a full-order observer is utilized to design a controller with robustness of every local model, which is treated as a local controller of the nonlinear core. The Kalman filter is contrived as an observer with robustness and the state feedback design with robustness is implemented via the robust pole assignment method. With the local models and local controllers, the flexibility partitioning of model and control is presented to design a decent flexibility controller of the nonlinear core at a random power level. A nonlinear core model and a flexibility controller at a random power level compose a core load following control subsystem. The combination of core load following control subsystems at all power levels is the core load following control system. Two global stability theorems are deduced to define that the core load following control system is globally asymptotically stable within the whole range of power level

  4. Physical activity levels of economically disadvantaged women living in the Olympic city of Rio de Janeiro.

    de Sousa-Mast, Fabiana R; Reis, Arianne C; Sperandei, Sandro; Gurgel, Luilma A; Vieira, Marcelo C; Pühse, Uwe

    2016-07-01

    The objective of this study was to analyze the physical activity patterns of women living in a low-income community located in close proximity to the 2016 Rio de Janeiro Olympic Park. Data (N = 140) were collected in June and July 2012 using the International Physical Activity Questionnaire. Findings indicated that the majority (54.8%) of participants reported high levels of physical activity. The domains that contributed the most to this pattern were occupational and household physical activity. Significantly, 88.1% of participants reported low physical activity levels during their leisure-time. In the transport-related domain, participants were relatively more active, but more than half of them (57%) spent less than 600 MET-minutes/week in this domain. The results highlighted the discrepancies between different physical activity domains. In addition, the findings also suggested that low-income women in our study engaged little in physical activity during their leisure time. Therefore, the proposed commitments found in the Rio de Janeiro Candidature File to host the 2016 Olympic Games to increase sport/physical activity participation within low-income communities in Rio de Janeiro need to be implemented effectively if this physical activity behavior during self-directed time is to be changed. PMID:26496170

  5. Hair-zinc levels determination in Algerian psoriatics using Instrumental Neutron Activation Analysis (INAA)

    Psoriasis is a multifactorial skin disease with an unknown etiology. Zinc has a positive impact on psoriasis. The aim of this study is to determine hair-zinc concentration in Algerian psoriatics. 58 psoriatics and 31 normal controls of both genders were selected. Hair zinc levels were determined using Instrumental Neutron Activation Analysis technique (INAA). Student's t-test and One-Way ANOVA were applied. The average zinc concentration for controls and patients were 152±53 μg/g and 167±52 μg/g respectively. They are not significantly different (p>0.05). Zn concentration for males and females controls and patients were 171±27 μg/g, 151±37 μg/g and 145±59 μg/g, 178±58 μg/g respectively. However, for females we have observed a significant difference (p<0.05). - Highlights: ► Psoriasis is a multifactorial skin disease with an unknown etiology. ► About 2–5% of global population in the world suffers from psoriasis. ► The aim of this study is to determine hair-zinc concentration in Algerian psoriatics. ► The average zinc concentration for controls and patients were 152±53 μg/g and 167±52 μg/g respectively.

  6. Electroencephalogram evidence for mirror neuron activity during the observation of drawn hand motion

    Huaping Zhu; Yaoru Sun; Wenya Duan

    2011-01-01

    The present study used electroencephalography to examine mu rhythm suppression (a putative index of human mirror neuron system activation) at frontal sites (F3, Fz and F4), central sites (C3, Cz and C4), parietal sites (P3, Pz and P4) and occipital sites (O1 and O2), while subjects observed real hand motion (real hand motion condition) and illustrative depictions of hand motion (drawn hand motion condition). Experimental data revealed that mu rhythm suppression was exhibited in the mirror neuron system when subjects observed both real and drawn hand motion. Moreover, the mu rhythm recorded at the F3, Fz, F4, and Pz poles was significantly suppressed while observing both stimulus types, but no obvious mu suppression occurred at the O1, O2 and O3 poles. These results suggest that the observation of drawings of human hand actions can activate the human mirror neuron system. This evidence supports the hypothesis that the mirror neuron system may be involved in intransitively abstract action understanding.

  7. Vagal activity is quadratically related to prosocial traits, prosocial emotions, and observer perceptions of prosociality.

    Kogan, Aleksandr; Oveis, Christopher; Carr, Evan W; Gruber, June; Mauss, Iris B; Shallcross, Amanda; Impett, Emily A; van der Lowe, Ilmo; Hui, Bryant; Cheng, Cecilia; Keltner, Dacher

    2014-12-01

    In the present article, we introduce the quadratic vagal activity-prosociality hypothesis, a theoretical framework for understanding the vagus nerve's involvement in prosociality. We argue that vagus nerve activity supports prosocial behavior by regulating physiological systems that enable emotional expression, empathy for others' mental and emotional states, the regulation of one's own distress, and the experience of positive emotions. However, we contend that extremely high levels of vagal activity can be detrimental to prosociality. We present 3 studies providing support for our model, finding consistent evidence of a quadratic relationship between respiratory sinus arrhythmia--the degree to which the vagus nerve modulates the heart rate--and prosociality. Individual differences in vagal activity were quadratically related to prosocial traits (Study 1), prosocial emotions (Study 2), and outside ratings of prosociality by complete strangers (Study 3). Thus, too much or too little vagal activity appears to be detrimental to prosociality. The present article provides the 1st theoretical and empirical account of the nonlinear relationship between vagal activity and prosociality. PMID:25243414

  8. Geomagnetic activity during 10 - 11 solar cycles that has been observed by old Russian observatories.

    Seredyn, Tomasz; Wysokinski, Arkadiusz; Kobylinski, Zbigniew; Bialy, Jerzy

    2016-07-01

    A good knowledge of solar-terrestrial relations during past solar activity cycles could give the appropriate tools for a correct space weather forecast. The paper focuses on the analysis of the historical collections of the ground based magnetic observations and their operational indices from the period of two sunspot solar cycles 10 - 11, period 1856 - 1878 (Bartels rotations 324 - 635). We use hourly observations of H and D geomagnetic field components registered at Russian stations: St. Petersburg - Pavlovsk, Barnaul, Ekaterinburg, Nertshinsk, Sitka, and compare them to the data obtained from the Helsinki observatory. We compare directly these records and also calculated from the data of the every above mentioned station IHV indices introduced by Svalgaard (2003), which have been used for further comparisons in epochs of assumed different polarity of the heliospheric magnetic field. We used also local index C9 derived by Zosimovich (1981) from St. Petersburg - Pavlovsk data. Solar activity is represented by sunspot numbers. The correlative and continuous wavelet analyses are applied for estimation of the correctness of records from different magnetic stations. We have specially regard to magnetic storms in the investigated period and the special Carrington event of 1-2 Sep 1859. Generally studied magnetic time series correctly show variability of the geomagnetic activity. Geomagnetic activity presents some delay in relation to solar one as it is seen especially during descending and minimum phase of the even 11-year cycle. This pattern looks similarly in the case of 16 - 17 solar cycles.

  9. VEx/VIRTIS and TNG/NICS cloud tracked winds at Venus' lower cloud level using nightside observations

    Machado, Pedro; Peralta, Javier; Luz, David; Gonçalves, Rúben

    2016-04-01

    We present results based on observations carried out with the Near Infrared Camera and Spectrograph (NICS) of the Telescopio Nazionale Galileo (TNG), in La Palma, on July 2012. We observed for periods of 2.5 hours starting just before dawn, for three consecutive nights. We acquired a set of images of the night side of Venus with the continuum K filter at 2.28 microns, which allows to monitor motions at the lower cloud level of the atmosphere of Venus, close to 48 km altitude. Our objective has been to measure the horizontal wind field in order to characterize the latitudinal zonal wind profile, to study variability, to help constrain the effect of large scale planetary waves in the maintenance of superrotation, and to map the cloud distribution. We will present first results of cloud tracked winds from ground-based TNG observations and winds retrieved from coordinated space-based VEx/VIRTIS observations. The cloud deck extends in altitude from 45 to 70 km, and can be divided into three main regions, centered at 48, 54 and 60 km. The lowest of these is the lower cloud, where fundamental dynamical exchanges that help maintain superrotation are thought to occur. The lower venusian atmosphere is a strong source of thermal radiation, with the gaseaous CO2 component allowing radiation to escape in windows at 1.74 and 2.28 μm. At these wavelengths radiation originates below 35 km, and unit opacity is reached at the lower cloud level, close to 48 km. Therefore, in these windows it is possible to observe the horizontal cloud structure, with thicker clouds seen silhouetted against the bright thermal background from the low atmosphere. Our objective is to provide direct absolute wind measurements and a map of cloud distribution at the lower cloud level in the Venus troposphere, in order to complement Venus Express (VEX) and other ground-based observations of the cloud layer wind regime. By continuous monitoring of the horizontal cloud structure at 2.28 μm (NICS Kcont filter

  10. AN ASSOCIATION OF CYTOKINE LEVELS WITH DISEASE ACTIVITY, AUTOANTIBODY LEVELS, AND JOINT DESTRUCTIVE CHANGES IN EARLY RHEUMATOID ARTHRITIS

    A. S. Avdeeva

    2015-09-01

    Full Text Available Objective: to assess the association of cytokine profile measures with disease activity, autoantibody levels, and joint destructive changes in patients with early rheumatoid arthritis (RA.Subjects and methods. Forty-five patients, including 35 women, with early RA were examined. Their median age was 53.5 [46; 59.5] years; the duration of the disease – 7.0 [4.0; 11.5] months; DAS28 – 5.8 [4.9; 6.4]; 91 and 96% of the patents were positive for rheumatoid factor (RF and anticyclic citrullinated peptide antibodies, respectively. Serum cytokine concentrations were estimated using the xMAP multiplex technology. The modified Sharp method was employed to quantify radiographic changes.Results and discussion. A group of 30 patients with high disease activity (DAS28 >5.1 had higher levels of interleukin (IL-6 (62.3 [36.1; 127.5] pg/ml and IP-10 (6367.8 [3682.7; 10691.3] pg/ml than 15 patients with moderate/low disease activity (DAS28 ≤5.1 (35.8 [13.4; 64.2] and 3222.6 [1881.0; 5671.9] pg/ml, respectively, p < 0.05. The patients highly positive for IgM RF had higher levels (pg/ml of proinflammatory cytokines, such as IL-1β, IL-2, IL-6, IL-12, IL-15, interferon-γ, and tumor necrosis factor-α; the chemokine monocyte chemotactic protein-1 and the growth factors IL-7 and vascular endothelial growth factor (4.8 [2.8; 19.3], 23.0 [7.1; 55.8], 64.2 [41.6; 170.5], 52.2 [30.9; 126.9], 2.4 [0.2; 11.2], 210.8 [119.9; 584.2], 90.7 [42.7; 307/9], 57.5 [26.1; 93.8], 54.9 [37.1; 123.7], and 143.3 [70.6; 249.6] pg/ml than those who were negative/lowly positive for IgM RF (2.3 [1.9; 3.1], 4.9 [2.9; 16.8], 24.9 [20.4; 45.4], 25.6 [19.9; 57.1], 0.2 [0.01; 1.65], 94.4 [86.3; 138.9], 37.3 [23.6; 47.7], 20.9 [12.3; 33.9], 32.6 [28.1; 37.8], 74.2 [53.5; 147.6], respectively (p < 0.05.Conclusion. There are significant differences in cytokine profile measures in patients with early RA in relation to disease activity and serum autoantibody levels.

  11. Automatic procedure go keep updated the activity levels for each radionuclide existing in a radioactivity laboratory

    An automatic procedure to keep updated the activity levels each radionuclide existing in a radioactivity laboratory, and its classification according to the Spanish Regulations on Nuclear and Radioactive Establishments is described. This procedure takes into account the mixed composition of each source and whether it is sealed or the activity and mass variation due to extraction or evaporation in non-sealed sources. For a given date and time, the procedure prints out a complete listing of the activity of each radioactive source, the accumulated activity for each radionuclide, for each kind of radionuclide and the actual classification of the laboratory according to the legal regulations above mentioned. (Author)

  12. A medaka model of cancer allowing direct observation of transplanted tumor cells in vivo at a cellular-level resolution.

    Hasegawa, Sumitaka; Maruyama, Kouichi; Takenaka, Hikaru; Furukawa, Takako; Saga, Tsuneo

    2009-08-18

    The recent success with small fish as an animal model of cancer with the aid of fluorescence technique has attracted cancer modelers' attention because it would be possible to directly visualize tumor cells in vivo in real time. Here, we report a medaka model capable of allowing the observation of various cell behaviors of transplanted tumor cells, such as cell proliferation and metastasis, which were visualized easily in vivo. We established medaka melanoma (MM) cells stably expressing GFP and transplanted them into nonirradiated and irradiated medaka. The tumor cells were grown at the injection sites in medaka, and the spatiotemporal changes were visualized under a fluorescence stereoscopic microscope at a cellular-level resolution, and even at a single-cell level. Tumor dormancy and metastasis were also observed. Interestingly, in irradiated medaka, accelerated tumor growth and metastasis of the transplanted tumor cells were directly visualized. Our medaka model provides an opportunity to visualize in vivo tumor cells "as seen in a culture dish" and would be useful for in vivo tumor cell biology. PMID:19666513

  13. Serum Visfatin Levels in Behcet's Disease Patients and Their Correlation with Disease Activity

    Cemile Tuğba Altunel

    2014-06-01

    Full Text Available Background and design: Behcet’s disease (BD is a chronic inflammatory disease. Genetic susceptibility, triggering infections and environmental factors that alter innate and acquired immunity are accused in its pathogenesis. Visfatin is a novel adipocytokine which exerts proinflammatory effects. In present study, by comparing serum visfatin levels of active Behcet patients with inactive patients and healthy controls, we investigated the role of visfatin in the inflammatory process of BD. Material and Methods: We enrolled 26 active, 26 inactive BD patients and 26 healthy controls in the study. Serum visfatin levels were analyzed by an enzyme-linked immunosorbent assay. White blood cell (WBC count, erythrocyte sedimentation rate (ESR, C-reactive protein (CRP and interleukin-6 (IL-6 levels were measured simultaneously and their correlation with visfatin levels were examined. Results: Age and gender distributions did not differ between study groups (P=0.736 and P=1.00 respectively. Serum visfatin levels were significantly higher in active (17.80±5.70 ng/mL and inactive patients (12.80±2.90 ng/mL than in control group (8.90±4.20 ng/mL, (P=0.00 for both comparisons. Active BD patients had significantly higher visfatin levels when compared to inactive patients (P=0.00. In all study groups visfatin levels were positively correlated with WBC count, ESH, CRP and IL-6 levels. Conclusion: Our results support the idea that visfatin plays a role in the inflammatory process of BD and suggests that visfatin may be a novel activity marker in BD.

  14. Physical Activity Volumes during Pregnancy: A Systematic Review and Meta-Analysis of Observational Studies Assessing the Association with Infant's Birth Weight

    Bisson, Michèle; Lavoie-Guénette, Joëlle; Tremblay, Angelo; Marc, Isabelle

    2016-01-01

    Objective This study aims to examine the association between different maternal physical activity exposures during pregnancy and infant's birth weight, body composition, and risk of inadequate weight. Methods Two reviewers (M.B. and J.L.G.) identified observational studies reporting total or leisure time activity during pregnancy and birth weight outcomes. Pooled analyses were performed to summarize the risk associated with high or moderate volumes of physical activity on birth weight. Results A total of 54 studies among 4,080 reported the association between physical activity and birth weight (37 studies) or risks of small or large birth weight. The association between physical activity and birth weight was evaluated by physical activity levels (low, moderate, or high). Despite heterogeneity, pooled results (23 studies) suggested that moderate levels of activity are associated with an increased birth weight (mean difference: 61.5 g, 95% confidence interval [CI]: 16.6, 106.5, 15 studies), while high levels were associated with lower birth weight (mean difference: −69.9 g, 95% CI: −114.8, −25.0, 15 studies). Data were insufficient to provide robust estimates for other outcomes. Conclusions The results of observational studies suggest an inverted u-shaped association between physical activity and birth weight, despite methodological variability. These results could help refining physical activity guidelines for pregnancy and provide guidance for future research. PMID:27127718

  15. Self-assessment analysis of health and physical activity level of military personnel

    Plavina L.

    2014-01-01

    Full Text Available Sport and physical activity is important and compulsory for military staff. They determine the execution of service duties and tasks. Respondents with low level of physical activity have difficulties achieving required fitness level and pass the annual physical tests. Staff officers aged 28 to 40 years completed questionnaires in 2009 (n=22, 2010 (n=30 and 2012 (n=39. Each questionnaire included twenty one questions which were then evaluated in points. The answers allowed us to collect information regarding their physical activity during service hours as well as after the working day. Questionnaires included also issues on harmful habits – sleep duration, smoking and use of alcohol; self-esteem of body mass as well. The respondents were divided into four groups according to the level of physical activity: low, moderate, good, high. The percentage of respondents with a high and good level of physical activity has increased from 22.7% to 68.9% during the analysed time period. Morning exercises and hardening (fitness procedures were not popular for military personnel. However, physical activities during the working hours have slightly increased: 31.8%, 43.3% and 48.9.3% respectively. In study years, it was found that respondents try to follow healthy eating habits and sleep regime. There is a slight decrease of respondents with obese and there is a slight increase of 22.7% to 27.6% of the respondents who are regular smokers .

  16. Seasonal changes in the white blood cell system, lyzozyme activity and cortisol level in Arabian brood mares and their foals.

    Gill, J; Kompanowska-Jezierska, E; Jakubow, K; Kott, A; Szumska, D

    1985-01-01

    In 34 pure-breed Arabian horses divided into four groups (Gr. I, ten pregnant mares; Gr. II, seven barren mares; Gr. III, ten foals born in 1981; Gr. IV, seven foals born in 1982) seasonal changes in the white blood cell system, cortisol level and lyzozyme activity were studied. Seasonal periodicity was found in all groups for the number of lymphocytes, segmented neutrophils and eosinophils and cortisol level. Leukocyte periodicity was found in three groups, but not in the barren mares. In lyzozyme activity there was periodicity in three groups but not in the youngest foals. In the stab neutrophils, basophils and monocytes no cycle was observed. The behaviour of the indices studied showed the influence of age of the horses (mature vs young) and the physiological state of the mares (pregnancy or barrenness). PMID:2863038

  17. GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.

    Tatham, Amy L; Crabtree, Mark J; Warrick, Nicholas; Cai, Shijie; Alp, Nicholas J; Channon, Keith M

    2009-05-15

    GTP cyclohydrolase I (GTPCH) is a key enzyme in the synthesis of tetrahydrobiopterin (BH4), a required cofactor for nitricoxide synthases and aromatic amino acid hydroxylases. Alterations of GTPCH activity and BH4 availability play an important role in human disease. GTPCH expression is regulated by inflammatory stimuli, in association with reduced expression of GTP cyclohydrolase feedback regulatory protein (GFRP). However, the relative importance of GTPCH expression versus GTPCH activity and the role of GFRP in relation to BH4 bioavailability remain uncertain. We investigated these relationships in a cell line with tet-regulated GTPCH expression and in the hph-1 mouse model of GTPCH deficiency. Doxycycline exposure resulted in a dose-dependent decrease in GTPCH protein and activity, with a strong correlation between GTPCH expression and BH4 levels (r(2) = 0.85, p GFRP expression or protein levels. GFRP overexpression and knockdown in tet-GCH cells did not alter GTPCH activity or BH4 levels, and GTPCH-specific knockdown in sEnd.1 endothelial cells had no effect on GFRP protein. In mouse liver we observed a graded reduction of GTPCH expression, protein, and activity, from wild type, heterozygote, to homozygote littermates, with a striking linear correlation between GTPCH expression and BH4 levels (r(2) = 0.82, p GFRP expression nor protein differed between wild type, heterozygote, nor homozygote mice, despite the substantial differences in BH4. We suggest that GTPCH expression is the primary regulator of BH4 levels, and changes in GTPCH or BH4 are not necessarily accompanied by changes in GFRP expression. PMID:19286659

  18. Estimating Sea Surface Salinity and Wind Using Combined Passive and Active L-Band Microwave Observations

    Yueh, Simon H.; Chaubell, Mario J.

    2012-01-01

    Several L-band microwave radiometer and radar missions have been, or will be, operating in space for land and ocean observations. These include the NASA Aquarius mission and the Soil Moisture Active Passive (SMAP) mission, both of which use combined passive/ active L-band instruments. Aquarius s passive/active L-band microwave sensor has been designed to map the salinity field at the surface of the ocean from space. SMAP s primary objectives are for soil moisture and freeze/thaw detection, but it will operate continuously over the ocean, and hence will have significant potential for ocean surface research. In this innovation, an algorithm has been developed to retrieve simultaneously ocean surface salinity and wind from combined passive/active L-band microwave observations of sea surfaces. The algorithm takes advantage of the differing response of brightness temperatures and radar backscatter to salinity, wind speed, and direction, thus minimizing the least squares error (LSE) measure, which signifies the difference between measurements and model functions of brightness temperatures and radar backscatter. The algorithm uses the conjugate gradient method to search for the local minima of the LSE. Three LSE measures with different measurement combinations have been tested. The first LSE measure uses passive microwave data only with retrieval errors reaching 1 to 2 psu (practical salinity units) for salinity, and 1 to 2 m/s for wind speed. The second LSE measure uses both passive and active microwave data for vertical and horizontal polarizations. The addition of active microwave data significantly improves the retrieval accuracy by about a factor of five. To mitigate the impact of Faraday rotation on satellite observations, the third LSE measure uses measurement combinations invariant under the Faraday rotation. For Aquarius, the expected RMS SSS (sea surface salinity) error will be less than about 0.2 psu for low winds, and increases to 0.3 psu at 25 m/s wind speed

  19. Physical Activity Levels and Domains Assessed by Accelerometry in German Adolescents from GINIplus and LISAplus.

    Maia P Smith

    Full Text Available Physical activity (PA is a well-known and underused protective factor for numerous health outcomes, and interventions are hampered by lack of objective data. We combined accelerometers with diaries to estimate the contributions to total activity from different domains throughout the day and week in adolescents.Accelerometric and diary data from 1403 adolescents (45% male, mean age 15.6 ± 0.5 years were combined to evaluate daily levels and domains of sedentary, light, and moderate-to-vigorous activity (MVPA during a typical week. Freedson's cutoff points were applied to determine levels of activity. Total activity was broken down into school physical education (PE, school outside PE, transportation to school, sport, and other time.About 2/3 of adolescents' time was spent sedentary, 1/3 in light activity, and about 5% in MVPA. Boys and girls averaged 46 (SD 22 and 38 (23 minutes MVPA per day. Adolescents were most active during leisure sport, spending about 30% of it in MVPA, followed by PE (about 20% transport to school (14% and either school class time or other time (3%. PE provided 5% of total MVPA, while leisure sport provided 16% and transportation to school 8%. School was the most sedentary part of the day with over 75% of time outside PE spent sedentary.These German adolescents were typical of Europeans in showing low levels of physical activity, with significant contributions from leisure sport, transportation and school PE. Leisure sport was the most active part of the day, and participation did not vary significantly by sex, study center (region of Germany or BMI. Transportation to school was frequent and thus accounted for a significant fraction of total MVPA. This indicates that even in a population with good access to dedicated sporting activities, frequent active transportation can add significantly to total MVPA.

  20. Monthly and sub-monthly hydrological variability: in-orbit validation by GRACE level 1B observations

    Eicker, Annette; Springer, Anne

    2016-06-01

    In this study, we present an approach to validate hydrological model output directly on the level of GRACE level 1B observations by analyzing K-band range-rate residuals. Modeled water mass variations are converted to simulated satellite observations and subtracted from the original measurements. This procedure bypasses the downward continuation and filtering steps generally required for water cycle analysis on the basis of gravity field maps. The goal of the study is twofold: (1) we demonstrate the feasibility of using residuals analysis for hydrological model validation in general and (2) we focus on the potential of the approach to investigate the signal content of temporally high-frequent (daily) modeled hydrological mass variations. In addition to the output of three different hydrological process models, we study mass changes computed from two different daily GRACE products. GRACE here serves as a reference, but its spatial resolution is limited and the daily models are not computed independently. Regarding aspect (1), our results show that the agreement of each of the models with GRACE varies strongly depending on geographical location. Aspect (2) is not only interesting for model validation, but it is also important in the context of improving the GRACE de-aliasing concept. We demonstrate that not only the daily GRACE models, but also the daily hydrological model output contains information on time scales smaller than 1 month. Realistically modeled or observed short-term hydrological mass changes may serve as additional de-aliasing product for GRACE and thus contribute to increasing the accuracy and resolution of future GRACE products.

  1. Investigating the Influence of Anthropogenic Forcing on Observed Mean and Extreme Sea Level Pressure Trends over the Mediterranean Region

    Armineh Barkhordarian

    2012-01-01

    Full Text Available We investigate whether the observed mean sea level pressure (SLP trends over the Mediterranean region in the period from 1975 to 2004 are significantly consistent with what 17 models projected as response of SLP to anthropogenic forcing (greenhouse gases and sulphate aerosols, GS. Obtained results indicate that the observed trends in mean SLP cannot be explained by natural (internal variability. Externally forced changes are detectable in all seasons, except spring. The large-scale component (spatial mean of the GS signal is detectable in all the 17 models in winter and in 12 of the 17 models in summer. However, the small-scale component (spatial anomalies about the spatial mean of GS signal is only detectable in winter within 11 of the 17 models. We also show that GS signal has a detectable influence on observed decreasing (increasing tendency in the frequencies of extremely low (high SLP days in winter and that these changes cannot be explained by internal climate variability. While the detection of GS forcing is robust in winter and summer, there are striking inconsistencies in autumn, where analysis points to the presence of an external forcing, which is not GS forcing.

  2. Lidar observations of Ca and K metallic layers from Arecibo and comparison with micrometeor sporadic activity

    Raizada, S.; Tepley, C. A.; Janches, D.; Friedman, J. S.; Zhou, Q.; Mathews, J. D.

    2004-04-01

    We report on the first simultaneous observations of Ca and K metallic layers using the low-latitude lidar systems located at the Arecibo Observatory in Puerto Rico (18.35°N, 66.75°W). We often observe sudden increases in both Ca and K densities during early morning hours on nights where meteor showers take place. During these periods, the Ca/K abundance ratio varied between 2 and 3. On occasion, differences were observed in Ca and K layers, which relate to differences in the chemistry of the two metals. It is known that metallic layers display distinct seasonal variations, but chemistry alone cannot explain the measured differences. Thus, we examined whether or not the seasonal distribution of micrometeoroids, derived from meteor observations using the Arecibo 430MHz radar, can account for the dissimilar metallic observations. We found that the deposition flux of micrometeoroids, with particle sizes ranging between 0.5 and 100μm, increased by a factor of two during the summer as compared with the winter, suggesting a seasonal variation of their sporadic activity. In addition, our data support the idea that differential ablation leads to a depletion of Ca atoms in the mesosphere.

  3. Using the EXIST Active Shields for Earth Occultation Observations of X-ray Sources

    Wilson, C A; Hong, J S; Grindlay, J E; Krawczynski, H; Wilson, Colleen A.

    2005-01-01

    The EXIST active shields, planned for the main detectors of the coded aperture telescope, will have approximately 15 times the area of the BATSE detectors, and they will have a good geometry on the spacecraft for viewing both the leading and trailing Earth's limb for occultation observations. These occultation observations will complement the imaging observations of EXIST and can extend them to higher energies. Earth occultation observations of the hard X-ray sky with BATSE on the Compton Gamma Ray Observatory developed and demonstrated the capabilities of large, flat, uncollimated detectors for applying this observation method. With BATSE, a catalog of 179 X-ray sources was monitored twice every spacecraft orbit for 9 years at energies above about 25 keV, resulting in 83 definite detections and 36 possible detections with 5 sigma detection sensitivities of 3.5-20 mcrab (20-430 keV) depending on the sky location. This catalog included four transients discovered with this technique and many variable objects (g...

  4. Photospheric and Coronal Observations of Abrupt Magnetic Restructuring in Two Flaring Active Regions

    Petrie, Gordon

    2016-05-01

    For two major X-class flares observed by the Solar Dynamics Observatory (SDO) and the Solar TErrestrial RElations Observatory Ahead (STEREO-A) spacecraft when they were close to quadrature, we compare major, abrupt changes in the photospheric magnetic vector field to changes in the observed coronal magnetic structure during the two flares. The Lorentz force changes in strong photospheric fields within active regions are estimated from time series of SDO Helioseismic and Magnetic Imager (HMI) vector magnetograms. These show that the major changes occurred in each case near the main neutral line of the region and in two neighboring twisted opposite-polarity sunspots. In each case the horizontal parallel field strengthened significantly near the neutral line while the azimuthal field in the sunspots decreased, suggesting that a flux rope joining the two sunspots collapsed across the neutral line with reduced magnetic pressure because of a reduced field twist component. At the same time, the coronal extreme ultraviolet (EUV) loop structure was observed by the Atmospheric Imaging Assembly (AIA) onboard SDO and the Extreme Ultraviolet Imager (EUVI) on STEREO-A to decrease significantly in height during each eruption, discontinuous changes signifying ejection of magnetized plasma, and outward-propagating continuous but abrupt changes consistent with loop contraction. An asymmetry in the observed EUV loop changes during one of the flares matches an asymmetry in the photospheric magnetic changes associated with that flare. The observations are discussed in terms of the well-known tether-cutting and breakout flare initiation models.

  5. Anti-parallel EUV flows observed along active region filament threads with Hi-C

    Alexander, Caroline E; Regnier, Stephane; Cirtain, Jonathan; Winebarger, Amy R; Golub, Leon; Kobayashi, Ken; Platt, Simon; Mitchell, Nick; Korreck, Kelly; DePontieu, Bart; DeForest, Craig; Weber, Mark; Title, Alan; Kuzin, Sergey

    2013-01-01

    Plasma flows within prominences/filaments have been observed for many years and hold valuable clues concerning the mass and energy balance within these structures. Previous observations of these flows primarily come from H-alpha and cool EUV lines (e.g., 304A) where estimates of the size of the prominence threads has been limited by the resolution of the available instrumentation. Evidence of `counter-steaming' flows has previously been inferred from these cool plasma observations but now, for the first time, these flows have been directly imaged along fundamental filament threads within the million degree corona (at 193A). In this work we present observations of an active region filament observed with Hi-C that exhibits anti-parallel flows along adjacent filament threads. Complementary data from SDO/AIA and HMI are presented. The ultra-high spatial and temporal resolution of Hi-C allow the anti-parallel flow velocities to be measured (70-80 km/s) and gives an indication of the resolvable thickness of the ind...

  6. A system for measuring thermal activation energy levels in silicon by thermally stimulated capacitance

    Cockrum, R. H.

    1982-01-01

    One method being used to determine energy level(s) and electrical activity of impurities in silicon is described. The method is called capacitance transient spectroscopy (CTS). It can be classified into three basic categories: the thermally stimulated capacitance method, the voltage-stimulated capacitance method, and the light-stimulated capacitance method; the first two categories are discussed. From the total change in capacitance and the time constant of the capacitance response, emission rates, energy levels, and trap concentrations can be determined. A major advantage of using CTS is its ability to detect the presence of electrically active impurities that are invisible to other techniques, such as Zeeman effect atomic absorption, and the ability to detect more than one electrically active impurity in a sample. Examples of detection of majority and minority carrier traps from gold donor and acceptor centers in silicon using the capacitance transient spectrometer are given to illustrate the method and its sensitivity.

  7. Low Amount of Salinomycin Greatly Increases Akt Activation, but Reduces Activated p70S6K Levels

    Sungpil Yoon

    2013-08-01

    Full Text Available The present study identified a novel salinomycin (Sal-sensitization mechanism in cancer cells. We analyzed the signal proteins Akt, Jnk, p38, Jak, and Erk1/2 in cancer cell lines that had arrested growth following low amounts of Sal treatment. We also tested the signal molecules PI3K, PDK1, GSK3β, p70S6K, mTOR, and PTEN to analyze the PI3K/Akt/mTOR pathway. The results showed that Sal sensitization positively correlates with large reductions in p70S6K activation. Interestingly, Akt was the only signal protein to be significantly activated by Sal treatment. The Akt activation appeared to require the PI3K pathway as its activation was abolished by the PI3K inhibitors LY294002 and wortmannin. The Akt activation by Sal was conserved in the other cell lines analyzed, which originated from other organs. Both Akt activation and C-PARP production were proportionally increased with increased doses of Sal. In addition, the increased levels of pAkt were not reduced over the time course of the experiment. Co-treatment with Akt inhibitors sensitized the Sal-treated cancer cells. The results thereby suggest that Akt activation is increased in cells that survive Sal treatment and resist the cytotoxic effect of Sal. Taken together; these results indicate that Akt activation may promote the resistance of cancer cells to Sal.

  8. CHANGES IN LEVELS OF ACTIVITY OF SERINE PROTEASES ACCOMPANY THE EXPOSURE OF COMMON BEAN (PHASEOLUS VULGARIS L. TO WATER DEFICIT

    M. Budič

    2008-09-01

    Full Text Available A wide variety of proteolytic enzymes exist in plants. On their levels depends protein turnover, a fundamental component in plant development and adaptation to environmental conditions. Cysteine proteases have frequently been reported to be influenced by drought, but only a few serine proteases (SP, among them the trypsin-like enzyme and two aminopeptidases from bean leaves (Bartels and Sunkar, 2005; Hieng et al., 2004. Our starting point was to identify proteolytic activities assigned to SPs that change with drought and then to characterize the corresponding proteases. A quantitative, analytical one-step method was used to separate endopeptidases and aminopeptidases active against a range of substrates in leaf extracts of plants grown in the field (FC. The influence of drought was determined for those of these activities which were confirmed as SPs, based on their inhibition by specific inhibitors. Under water deficit in plants grown under controlled conditions (CC their levels changed in different ways. The levels of SP activities in FC plants, observed during a period of relative drought, were similar to those measured in mildly stressed CC plants. The partial characterisations of some of these SPs will be presented. Our results point to a number of roles for different SPs in the plant response to water stress, which could range from enhanced protein turnover to limited proteolysis at specific sites.

  9. Magma-tectonic interactions in an area of active extension; a review of recent observations, models and interpretations from Iceland

    Pedersen, Rikke; Sigmundsson, Freysteinn; Drouin, Vincent; Rafn Heimisson, Elías; Parks, Michelle; Dumont, Stéphanie; Árnadóttir, Þóra; Masterlark, Timothy; Ófeigsson, Benedíkt G.; Jónsdóttir, Kristín; Hooper, Andrew

    2016-04-01

    The geological setting of Iceland provides rich opportunities of studying magma-tectonic interactions, as it constitutes Earth's largest part of the mid-oceanic ridge system exposed above sea level. A series of volcanic and seismic zones accommodate the ~2 cm/year spreading between the North-American and Eurasian plates, and the Icelandic hot-spot conveniently provides the means of exposing this oceanic crust-forming setting above sea-level. Both extinct and active plumbing system structures can be studied in Iceland, as the deeply eroded tertiary areas provide views into the structures of extinct volcanic systems, and active processes can be inferred on in the many active volcanic systems. A variety of volcanic and tectonic processes cause the Icelandic crust to deform continuously, and the availability of contemporaneous measurements of crustal deformation and seismicity provide a powerful data set, when trying to obtain insight into the processes working at depth, such as magma migration through the uppermost lithosphere, magma induced host rock deformation and volcanic eruption locations and styles. The inferences geodetic and seismic datasets allow on the active plate spreading processes and subsurface magma movements in Iceland will be reviewed, in particular in relation to the Northern Volcanic Zone (NVZ). There the three phases of a rifting cycle (rifting, post-rifting, inter-rifting) have been observed. The NVZ is an extensional rift segment, bounded to the south by the Icelandic mantle plume, and to the north by the Tjörnes transform zone. The NVZ has typically been divided into five partly overlapping en-echelon fissure swarms, each with a central main volcanic production area. Most recently, additional insight into controlling factors during active rifting has been provided by the Bárðarbunga activity in 2014-2015 that included a major rifting event, the largest effusive eruption in Iceland since 1783, and a gradual caldera collapse. It is evident

  10. 226Ra and 228Ra activity levels in potable drinking water supplied to pharmaceutical companies in India

    The low level 226Ra and 228Ra activities were measured in Potable water samples received by pharmaceutical companies located in Maharashtra, Goa, Gujarat, Madhya Pradesh and Himachal Pradesh through private Borewell Supply and Municipal water Supply units. Radium in drinking water and food enhances the ingestion dose due to its long radiological and biological half-life. The Radium activity level in the fresh water was supposed to be within the limits prescribed by USEPA Guideline for Drinking Water Quality, 40 CFR 141,a Code of Federal Regulation. Higher concentration of Radium can be easily measured by Gamma spectrometry. The paper gives the low levels of radium isotopes present in the water samples which are not detectable successfully by simple gamma spectrometry. A separation chemistry considering Radium isotopes decay scheme and chemical similarity to Calcium was adapted to measure the activity with sequential chemical separation method followed by determining the alpha and beta activity of individual radium isotopes. In bore well water 226Ra activity level was in the range of 0.21 to 60±3.7 mBq/l and 228Ra level was in the range of 5.48 to 111.9±12.2 mBq/l while in Municipal water supply 226Ra and 228Ra was observed to be in the range of 0.32 to 28.89 mBq/l and 2.19 to 117.43 mBq/l respectively. A combined 226Ra+228Ra activity was observed to be in the range of 2.63 to 171.9±12.75 mBq/l which is very much within the prescribed limits. The investigation indicated that 228Ra activity is comparatively more than 226Ra indicating the water source to be from Thorium rich locations.The expected dose assessed was in the range of 13.18 to 0.04 μSv/y which is well within the limit of 0.1 mSv/y. (author)

  11. Self-determined motivation towards physical activity in adolescents treated for obesity: an observational study

    Theuwis Lotte

    2011-09-01

    Full Text Available Abstract Background Within the Self-Determination Theory (SDT framework, the first major study aim was to investigate the SDT tenets in an obese adolescent population by examining the factor structure of the Behavioural Regulation in Exercise Questionnaire-2 (BREQ-2 and by investigating associations between physical activity (PA and motivation in obese adolescents. The second aim was to study differences in motivation according to adolescents' educational level, since lower educated obese adolescent are a sub-risk group for lower PA levels among the obese adolescents. The third aim was to investigate whether attending a residential obesity treatment program could lead to an increase in autonomous motivation towards PA and to see if the treatment effect on motivation was different in low versus high educated youth. Methods For the first study aim, the sample comprised 177 obese adolescents at the start of a 10-month multidisciplinary residential obesity treatment program (BMI = 35.9 ± 6.0 kg/m2, 15.1 ± 1.5 years, 62% girls. A subsample of 65 adolescents (stratified by educational level were divided into low (n = 34 versus high educated (n = 31 as part of the second and third study aim. Motivation was assessed using the BREQ-2 and PA using the Flemish Physical Activity Questionnaire. Results Exploratory factor analysis showed sufficient validations with the original factor for 17 out of 19 BREQ-2 items. Significant positive correlations were found between PA and the composite score of relative autonomy (r = 0.31, p Conclusions The BREQ-2 can be used in an obese adolescent population. Higher levels of autonomous motivation towards PA were related to higher PA levels. Adolescents had increases in both autonomous and controlled forms of motivation during treatment. Special attention for lower educated adolescents during treatment is needed, as they have a lower autonomous motivation at the start of treatment and an increase in introjected

  12. Analysis of nearly simultaneous x-ray and optical observations of active galactic nuclei

    Rosemary Hill optical and EINSTEIN X-ray observations of a sample of 36 galactic nuclei (AGN) were reduced and analyzed. Seventy-two x-ray observations of these sources were reduced, nineteen of which yielded spectral information. Of these spectra observations, significant hydrogen column densities above the galactic value were required for nine of the active galactic nuclei. X-ray variability was detected in eight of the eleven sources which were observed more than once by EINSTEIN. Correlations between the x-ray and optical luminosities were investigated using the Jefferys method of least squares. This method allows for errors in both variables. The results indicate a strong correlation between the x-ray and optical luminosities for the entire sample. Division of the sample into groups with similar optical variability characteristics show that the less violently violent variable AGN are more highly correlated than the violently variable blazars. Infrared and radio observations were combined with the x-ray and optical observations of six AGN. These sources were modelled in terms of the synchrotron-self-Compton model. The turnover frequency falls between the infrared and radio data and reliable estimates of this parameter are difficult to estimate. Therefore the results were found as a function of the turnover frequency. Four sources required relativistic bulk motion or beaming. Multifrequency spectra made at different times for one individual source, 0235+164, required different amounts of beaming to satisfy the x-ray observations. Sizes of the emitting regions for the sources modelled ranged from 0.5 parsec to 1.0 parsec

  13. Decreased plasma levels of soluble CD18 link leukocyte infiltration with disease activity in spondyloarthritis

    Kragstrup, Tue Wenzel; Jalilian, Babak; Hvid, Malene;

    2014-01-01

    A patients compared with healthy volunteers (P < 0.001) with the lowest levels in the HLA-B27-positive subgroup (P < 0.05). In a multiple regression model the sCD18 levels exhibited an inverse correlation with the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) (P < 0.05), the level of morning......INTRODUCTION: Spondyloarthritis (SpA) comprises a group of diseases often associated with HLA-B27 and characterized by inflammation of the entheses and joints of the axial skeleton. The inflammatory process in SpA is presumably driven by innate immune cells but still poorly understood. Thus, new...... of arthritis patients to have anti-inflammatory functions. Here, we study the mechanisms for these alterations and their association with SpA disease activity. METHODS: Plasma levels of sCD18 in a study population with 84 SpA patients and matched healthy controls were analyzed with a time resolved...

  14. Trainability of muscular activity level during maximal voluntary co-contraction: comparison between bodybuilders and nonathletes.

    Sumiaki Maeo

    Full Text Available Antagonistic muscle pairs cannot be fully activated simultaneously, even with maximal effort, under conditions of voluntary co-contraction, and their muscular activity levels are always below those during agonist contraction with maximal voluntary effort (MVE. Whether the muscular activity level during the task has trainability remains unclear. The present study examined this issue by comparing the muscular activity level during maximal voluntary co-contraction for highly experienced bodybuilders, who frequently perform voluntary co-contraction in their training programs, with that for untrained individuals (nonathletes. The electromyograms (EMGs of biceps brachii and triceps brachii muscles during maximal voluntary co-contraction of elbow flexors and extensors were recorded in 11 male bodybuilders and 10 nonathletes, and normalized to the values obtained during the MVE of agonist contraction for each of the corresponding muscles (% EMGMVE. The involuntary coactivation level in antagonist muscle during the MVE of agonist contraction was also calculated. In both muscles, % EMGMVE values during the co-contraction task for bodybuilders were significantly higher (P<0.01 than those for nonathletes (biceps brachii: 66±14% in bodybuilders vs. 46±13% in nonathletes, triceps brachii: 74±16% vs. 57±9%. There was a significant positive correlation between a length of bodybuilding experience and muscular activity level during the co-contraction task (r = 0.653, P = 0.03. Involuntary antagonist coactivation level during MVE of agonist contraction was not different between the two groups. The current result indicates that long-term participation in voluntary co-contraction training progressively enhances muscular activity during maximal voluntary co-contraction.

  15. Trainability of muscular activity level during maximal voluntary co-contraction: comparison between bodybuilders and nonathletes.

    Maeo, Sumiaki; Takahashi, Takumi; Takai, Yohei; Kanehisa, Hiroaki

    2013-01-01

    Antagonistic muscle pairs cannot be fully activated simultaneously, even with maximal effort, under conditions of voluntary co-contraction, and their muscular activity levels are always below those during agonist contraction with maximal voluntary effort (MVE). Whether the muscular activity level during the task has trainability remains unclear. The present study examined this issue by comparing the muscular activity level during maximal voluntary co-contraction for highly experienced bodybuilders, who frequently perform voluntary co-contraction in their training programs, with that for untrained individuals (nonathletes). The electromyograms (EMGs) of biceps brachii and triceps brachii muscles during maximal voluntary co-contraction of elbow flexors and extensors were recorded in 11 male bodybuilders and 10 nonathletes, and normalized to the values obtained during the MVE of agonist contraction for each of the corresponding muscles (% EMGMVE). The involuntary coactivation level in antagonist muscle during the MVE of agonist contraction was also calculated. In both muscles, % EMGMVE values during the co-contraction task for bodybuilders were significantly higher (Pbodybuilders vs. 46±13% in nonathletes, triceps brachii: 74±16% vs. 57±9%). There was a significant positive correlation between a length of bodybuilding experience and muscular activity level during the co-contraction task (r = 0.653, P = 0.03). Involuntary antagonist coactivation level during MVE of agonist contraction was not different between the two groups. The current result indicates that long-term participation in voluntary co-contraction training progressively enhances muscular activity during maximal voluntary co-contraction. PMID:24260233

  16. XMM FOLLOW-UP OBSERVATIONS OF THREE SWIFT BAT-SELECTED ACTIVE GALACTIC NUCLEI

    We present XMM-Newton observations of three active galactic nuclei (AGNs) taken as part of a hunt to find very heavily obscured Compton-thick AGNs. For obscuring columns greater than 1025 cm-2, AGNs are only visible at energies below 10 keV via reflected/scattered radiation, characterized by a flat power law. We therefore selected three objects (ESO 417-G006, IRAS 05218-1212, and MCG -01-05-047) from the Swift Burst Alert Telescope (BAT) hard X-ray survey catalog with Swift X-ray Telescope (XRT) 0.5-10 keV spectra with flat power-law indices as candidate Compton-thick sources for follow-up observations with the more sensitive instruments on XMM-Newton. The XMM spectra, however, rule out reflection-dominated models based on the weakness of the observed Fe Kα lines. Instead, the spectra are well fit by a model of a power-law continuum obscured by a Compton-thin absorber plus a soft excess. This result is consistent with previous follow-up observations of two other flat-spectrum BAT-detected AGNs. Thus, out of the six AGNs in the 22 month BAT catalog with apparently flat Swift XRT spectra, all five that have had follow-up observations are not likely Compton thick. We also present new optical spectra of two of these objects, IRAS 05218-1212 and MCG -01-05-047. Interestingly, though both the AGNs have similar X-ray spectra, their optical spectra are completely different, adding evidence against the simplest form of the geometric unified model of AGNs. IRAS 05218-1212 appears in the optical as a Seyfert 1, despite the ∼8.5 x 1022 cm-2 line-of-sight absorbing column indicated by its X-ray spectrum. MCG -01-05-047's optical spectrum shows no sign of AGN activity; it appears as a normal galaxy.

  17. Activity associated with coronal mass ejections at solar minimum - SMM observations from 1984-1986

    St. Cyr, O. C.; Webb, D. F.

    1991-01-01

    Seventy-three coronal mass ejections (CMEs) observed by the coronagraph aboard SMM between 1984 and 1986 were examined in order to determine the distribution of various forms of solar activity that were spatially and temporally associated with mass ejections during solar minimum phase. For each coronal mass ejection a speed was measured, and the departure time of the transient from the lower corona estimated. Other forms of solar activity that appeared within 45 deg longitude and 30 deg latitude of the mass ejection and within +/-90 min of its extrapolated departure time were explored. The statistical results of the analysis of these 73 CMEs are presented, and it is found that slightly less than half of them were infrequently associated with other forms of solar activity. It is suggested that the distribution of the various forms of activity related to CMEs does not change at different phases of the solar cycle. For those CMEs with associations, it is found that eruptive prominences and soft X-rays were the most likely forms of activity to accompany the appearance of mass ejections.

  18. Cytotoxic activities of amentoflavone against human breast and cervical cancers are mediated by increasing of PTEN expression levels due to peroxisomes proliferate-activated receptor {gamma} activation

    Lee, Eunjung; Shin, Soyoung; Lee, Jeeyoung; Lee, So Jung; Kim, Jinkyoung; Yoon, Doyoung; Kim, Yangmee [Konkuk Univ., Seoul (Korea, Republic of); Woo, Eunrhan [Chosun Univ., Gwangju (Korea, Republic of)

    2012-07-15

    Human peroxisomes proliferate-activated receptor gamma (hPPAR{gamma}) has been implicated in numerous pathologies, including obesity, diabetes, and cancer. Previously, we verified that amentoflavone is an activator of hPPAR{gamma} and probed the molecular basis of its action. In this study, we investigated the mechanism of action of amentoflavone in cancer cells and demonstrated that amentoflavone showed strong cytotoxicity against MCF-7 and HeLa cancer cell lines. We showed that hPPAR{gamma} expression in MCF-7 and HeLa cells is specifically stimulated by amentoflavone, and suggested that amentoflavone-induced cytotoxic activities are mediated by activation of hPPAR{gamma} in these two cancer cell lines. Moreover, amentoflavone increased PTEN levels in these two cancer cell lines, indicating that the cytotoxic activities of amentoflavone are mediated by increasing of PTEN expression levels due to hPPAR{gamma} activation.

  19. Cytotoxic activities of amentoflavone against human breast and cervical cancers are mediated by increasing of PTEN expression levels due to peroxisomes proliferate-activated receptor γ activation

    Human peroxisomes proliferate-activated receptor gamma (hPPARγ) has been implicated in numerous pathologies, including obesity, diabetes, and cancer. Previously, we verified that amentoflavone is an activator of hPPARγ and probed the molecular basis of its action. In this study, we investigated the mechanism of action of amentoflavone in cancer cells and demonstrated that amentoflavone showed strong cytotoxicity against MCF-7 and HeLa cancer cell lines. We showed that hPPARγ expression in MCF-7 and HeLa cells is specifically stimulated by amentoflavone, and suggested that amentoflavone-induced cytotoxic activities are mediated by activation of hPPARγ in these two cancer cell lines. Moreover, amentoflavone increased PTEN levels in these two cancer cell lines, indicating that the cytotoxic activities of amentoflavone are mediated by increasing of PTEN expression levels due to hPPARγ activation

  20. Level and intensity of objectively assessed physical activity among pregnant women from urban Ethiopia

    Hjorth Mads F

    2012-12-01

    Full Text Available Abstract Background Women in low-income countries are generally considered to have a high physical workload which is sustained during pregnancy. Although most previous studies have been based on questionnaires a recent meta-analysis of doubly labeled water data has raised questions about the actual amount of physical activity performed. In this study we report objectively assessed levels of physical activity, cardiorespiratory fitness and muscular fitness among pregnant urban Ethiopian women, and their association with demographic characteristics and anthropometric measures. Methods Physical activity was measured for seven consecutive days in 304 women using a combined uniaxial accelerometer and heart rate sensor. Activity energy expenditure was determined using a group calibration in a branched equation model framework. Type and duration of activities were reported using a 24-hour physical activity recall and grip strength was assessed using a dynamometer. Results Median (interquartile-range, IQR activity energy expenditure was 31.1 (23.7-42.0 kJ/kg/day corresponding to a median (IQR physical activity level of 1.46 (1.39-1.58. Median (IQR time in sedentary, light, and moderate-to-vigorous intensity was 1100 (999–1175, 303 (223–374 and 40 (22–69 min/day, respectively. Mean (standard deviation sleeping heart rate was 73.6 (8.0 beats/min and grip strength was 21.6 (4.5 kg. Activity energy expenditure was 14% higher for every 10 cm2 difference in arm muscle area and 10% lower for every 10 cm2 difference in arm fat area and 10-week difference in gestational age. Conclusion The level and intensity of physical activity among pregnant women from urban Ethiopia is low compared to non-pregnant women from other low income countries as well as pregnant European women from high-income countries.