WorldWideScience

Sample records for actinium 206

  1. Extraction of actinium with di-(2-ethylhexyl)phosphoric acid from hydrochloric and nitric acid solutions

    The extraction of actinium with HDEHP from Cl- and NO3- systems has been investigated. It was found that extraction of actinium from HCl solutions is much better than from HNO3 solutions. Stability constants of actinium complexes Ac(X-)+2 with Cl- and NO3- ligands were determined. Our results show that the actinium formed less stable complexes with Cl- than with NO3- ligands. 5 refs., 3 figs., 1 tab. (author)

  2. IT 206 Uop Material - it206dotcom

    honey

    2015-01-01

    IT 206 Entire Course For more course tutorials visit www.uopit206.com   IT 206 Week 1 CheckPoint Formatting Issues IT 206 Week 1 DQ 1 and DQ 2 IT 206 Week 2 CheckPoint Knowing Where You Placed Your Document IT 206 week 2 Assignment Microsoft Word Exercise IT 206 Week 3 CheckPoint Simplifying Your Excel Usage IT 206 week 3 DQ 1 and DQ 2 IT 206 Week 4 CheckPoint The Risk of Macros IT 206 Week 4 Assignment Microsoft Excel Exercise IT 206 Week ...

  3. The sorption of polonium, actinium and protactinium onto geological materials

    This paper describes a combined experimental and modeling program of generic sorption studies to increase confidence in the performance assessment for a potential high-level radioactive waste repository in Japan. The sorption of polonium, actinium and protactinium onto geological materials has been investigated. Sorption of these radioelements onto bentonite, tuff and granodiorite from equilibrated de-ionized water was studied under reducing conditions at room temperature. In addition, the sorption of actinium and protactinium was investigated at 60 C. Thermodynamic chemical modeling was carried out to aid interpretation of the results

  4. Discovery of the actinium, thorium, protactinium, and uranium isotopes

    Fry, C; Thoennessen, M

    2012-01-01

    Currently, 31 actinium, 31 thorium, 28 protactinium, and 23 uranium isotopes have so far been observed; the discovery of these isotopes is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  5. Separation of Actinium 227 from the uranium minerals

    The purpose of this work was to separate Actinium 227, whose content is 18%, from the mineral carnotite found in Gomez Chihuahua mountain range in Mexico. The mineral before processing is is pre-concentrated and passed, first through anionic exchange resins, later the eluate obtained is passed through cationic resins. The resins were 20-50 MESH QOWEX and 100-200 MESH 50 X 8-20 in some cased 200-400 MESH AG 50W-X8, 1X8 in other cases. The eluates from the ionic exchange were electrodeposited on stainless steel polished disc cathode and platinum electrode as anode; under a current ODF 10mA for 2.5 to 5 hours and of 100mA for .5 of an hour. it was possible to identify the Actinium 227 by means of its descendents, TH-227 and RA-223, through alpha spectroscopy. Due to the radiochemical purity which the electro deposits were obtained the Actinium 227 was low and was not quantitatively determined. A large majority of the members of the natural radioactive series 3 were identified and even alpha energies reported in the literature with very low percentages of non-identified emissions were observed. We conclude that a more precise study is needed concerning ionic exchange and electrodeposit to obtain an Actinium 227 of radiochemical purity. (Author)

  6. Spectroscopic and computational investigation of actinium coordination chemistry.

    Ferrier, Maryline G; Batista, Enrique R; Berg, John M; Birnbaum, Eva R; Cross, Justin N; Engle, Jonathan W; La Pierre, Henry S; Kozimor, Stosh A; Lezama Pacheco, Juan S; Stein, Benjamin W; Stieber, S Chantal E; Wilson, Justin J

    2016-01-01

    Actinium-225 is a promising isotope for targeted-α therapy. Unfortunately, progress in developing chelators for medicinal applications has been hindered by a limited understanding of actinium chemistry. This knowledge gap is primarily associated with handling actinium, as it is highly radioactive and in short supply. Hence, Ac(III) reactivity is often inferred from the lanthanides and minor actinides (that is, Am, Cm), with limited success. Here we overcome these challenges and characterize actinium in HCl solutions using X-ray absorption spectroscopy and molecular dynamics density functional theory. The Ac-Cl and Ac-OH2O distances are measured to be 2.95(3) and 2.59(3) Å, respectively. The X-ray absorption spectroscopy comparisons between Ac(III) and Am(III) in HCl solutions indicate Ac(III) coordinates more inner-sphere Cl(1-) ligands (3.2±1.1) than Am(III) (0.8±0.3). These results imply diverse reactivity for the +3 actinides and highlight the unexpected and unique Ac(III) chemical behaviour. PMID:27531582

  7. Production of high-purity radium-223 from legacy actinium-beryllium neutron sources.

    Soderquist, Chuck Z; McNamara, Bruce K; Fisher, Darrell R

    2012-07-01

    Radium-223 is a short-lived alpha-particle-emitting radionuclide with potential applications in cancer treatment. Research to develop new radiopharmaceuticals employing (223)Ra has been hindered by poor availability due to the small quantities of parent actinium-227 available world-wide. The purpose of this study was to develop innovative and cost-effective methods to obtain high-purity (223)Ra from (227)Ac. We obtained (227)Ac from two surplus actinium-beryllium neutron generators. We retrieved the actinium/beryllium buttons from the sources and dissolved them in a sulfuric-nitric acid solution. A crude actinium solid was recovered from the solution by coprecipitation with thorium fluoride, leaving beryllium in solution. The crude actinium was purified to provide about 40 milligrams of actinium nitrate using anion exchange in methanol-water-nitric acid solution. The purified actinium was then used to generate high-purity (223)Ra. We extracted (223)Ra using anion exchange in a methanol-water-nitric acid solution. After the radium was separated, actinium and thorium were then eluted from the column and dried for interim storage. This single-pass separation produces high purity, carrier-free (223)Ra product, and does not disturb the (227)Ac/(227)Th equilibrium. A high purity, carrier-free (227)Th was also obtained from the actinium using a similar anion exchange in nitric acid. These methods enable efficient production of (223)Ra for research and new alpha-emitter radiopharmaceutical development. PMID:22697483

  8. IT 206 courses / snaptutorial

    IT 210 snaptutorial

    2015-01-01

    For more classes visit www.snaptutorial.com   IT 206 Week 1 CheckPoint Formatting Issues IT 206 Week 1 DQ 1 and DQ 2 IT 206 Week 2 CheckPoint Knowing Where You Placed Your Document IT 206 Week 2 Assignment Microsoft Word Exercise IT 206 Week 3 CheckPoint Simplifying Your Excel Usage IT 206 Week 3 DQ 1 and DQ 2 IT 206 Week 4 CheckPoint The Risk of Macros IT 206 Week 4 Assignment Microsoft Excel Exercise IT 206 Week 5 CheckPoint Mail Merging ...

  9. Radium, thorium, and actinium extraction from seawater using an improved manganese-oxide-coated fiber

    Laboratory experiments were conducted to determine the efficiency with which improved manganese-oxide-coated acrylic fibers extract radium, thorium, and actinium from seawater. Tests were made using surface seawater spiked with 227Ac, 227Th and 223Ra. For sample volumes of approximately 30 liters and flow rates up to 0.5 liters per minute, radium and actinium are removed quantitatively. Approximately 80-95% of the thorium is removed under these same conditions. (Auth.)

  10. ACC 206 NEW TUTORIAL / Uoptutorial

    Honey Singh

    2015-01-01

    For more course tutorials visit www.uoptutorial.com   ACC 206 Week 1 Assignment Chapter One Problems   ACC 206 Week 1 DQ1 Cash Flows Information   ACC 206 Week 1 DQ2 Apple's Cash Flow   ACC 206 Week 2 Assignment Chapter Two and Three Problems   ACC 206 Week 2 DQ1 Stock Features   ACC 206 Week 2 DQ2 Role of Management Accounting   ACC 206 Week 2 Journal Institute of Management Accounting &nb...

  11. Production of Actinium-225 via High Energy Proton Induced Spallation of Thorium-232

    Harvey, James T.; Nolen, Jerry; Vandergrift, George; Gomes, Itacil; Kroc, Tom; Horwitz, Phil; McAlister, Dan; Bowers, Del; Sullivan, Vivian; Greene, John

    2011-12-30

    The science of cancer research is currently expanding its use of alpha particle emitting radioisotopes. Coupled with the discovery and proliferation of molecular species that seek out and attach to tumors, new therapy and diagnostics are being developed to enhance the treatment of cancer and other diseases. This latest technology is commonly referred to as Alpha Immunotherapy (AIT). Actinium-225/Bismuth-213 is a parent/daughter alpha-emitting radioisotope pair that is highly sought after because of the potential for treating numerous diseases and its ability to be chemically compatible with many known and widely used carrier molecules (such as monoclonal antibodies and proteins/peptides). Unfortunately, the worldwide supply of actinium-225 is limited to about 1,000mCi annually and most of that is currently spoken for, thus limiting the ability of this radioisotope pair to enter into research and subsequently clinical trials. The route proposed herein utilizes high energy protons to produce actinium-225 via spallation of a thorium-232 target. As part of previous R and D efforts carried out at Argonne National Laboratory recently in support of the proposed US FRIB facility, it was shown that a very effective production mechanism for actinium-225 is spallation of thorium-232 by high energy proton beams. The base-line simulation for the production rate of actinium-225 by this reaction mechanism is 8E12 atoms per second at 200 MeV proton beam energy with 50 g/cm2 thorium target and 100 kW beam power. An irradiation of one actinium-225 half-life (10 days) produces {approx}100 Ci of actinium-225. For a given beam current the reaction cross section increases slightly with energy to about 400 MeV and then decreases slightly for beam energies in the several GeV regime. The object of this effort is to refine the simulations at proton beam energies of 400 MeV and above up to about 8 GeV. Once completed, the simulations will be experimentally verified using 400 MeV and 8 Ge

  12. Production of Actinium-225 via High Energy Proton Induced Spallation of Thorium-232

    The science of cancer research is currently expanding its use of alpha particle emitting radioisotopes. Coupled with the discovery and proliferation of molecular species that seek out and attach to tumors, new therapy and diagnostics are being developed to enhance the treatment of cancer and other diseases. This latest technology is commonly referred to as Alpha Immunotherapy (AIT). Actinium-225/Bismuth-213 is a parent/daughter alpha-emitting radioisotope pair that is highly sought after because of the potential for treating numerous diseases and its ability to be chemically compatible with many known and widely used carrier molecules (such as monoclonal antibodies and proteins/peptides). Unfortunately, the worldwide supply of actinium-225 is limited to about 1,000mCi annually and most of that is currently spoken for, thus limiting the ability of this radioisotope pair to enter into research and subsequently clinical trials. The route proposed herein utilizes high energy protons to produce actinium-225 via spallation of a thorium-232 target. As part of previous R and D efforts carried out at Argonne National Laboratory recently in support of the proposed US FRIB facility, it was shown that a very effective production mechanism for actinium-225 is spallation of thorium-232 by high energy proton beams. The base-line simulation for the production rate of actinium-225 by this reaction mechanism is 8E12 atoms per second at 200 MeV proton beam energy with 50 g/cm2 thorium target and 100 kW beam power. An irradiation of one actinium-225 half-life (10 days) produces ∼100 Ci of actinium-225. For a given beam current the reaction cross section increases slightly with energy to about 400 MeV and then decreases slightly for beam energies in the several GeV regime. The object of this effort is to refine the simulations at proton beam energies of 400 MeV and above up to about 8 GeV. Once completed, the simulations will be experimentally verified using 400 MeV and 8 GeV protons

  13. Neutron-Induced Fission of Actinium-227, Protactinium-231 and Neptunium-237: Mass Distribution

    Results of radiochemical studies on the mass distribution in the neutron-induced fission of actinium-227, protactinium-231 and neptunium-237 have been presented. This work has been carried out as part of a programme to determine the mass distribution in the fission of heavy elements as a function of Z and A. All irradiations have been carried out in the core of the swimming-pool type reactor APSARA with cadmium shielding wherever necessary. Relative yields of several fission product nuclides have been obtained by a method involving a comparison of the fission product activities from the respective targets with those formed from uranium-235 simultaneously irradiated. Thermal-neutron fission yields of uranium-235 have been assumed. These results indicate a predominantly asymmetric mass distribution in all the three cases, and also a distinct though small symmetric peak in the case of actinium-227. (author)

  14. A new method for the determination of low-level actinium-227 in geological samples

    We developed a new method for the determination of 227Ac in geological samples. The method uses extraction chromatographic techniques and alpha-spectrometry and is applicable for a range of natural matrices. Here we report on the procedure and results of the analysis of water (fresh and seawater) and rock samples. Water samples were acidified and rock samples underwent total dissolution via acid leaching. A DGA (N,N,N',N'-tetra-n-octyldiglycolamide) extraction chromatographic column was used for the separation of actinium. The actinium fraction was prepared for alpha spectrometric measurement via cerium fluoride micro-precipitation. Recoveries of actinium in water samples were 80 ± 8 % (number of analyses n = 14) and in rock samples 70 ± 12 % (n = 30). The minimum detectable activities (MDA) were 0.017-0.5 Bq kg-1 for both matrices. Rock sample 227Ac activities ranged from 0.17 to 8.3 Bq kg-1 and water sample activities ranged from below MDA values to 14 Bq kg-1of 227Ac. From the analysis of several standard rock and water samples with the method we found very good agreement between our results and certified values. (author)

  15. IT 206 UOP COURSE TUTORIAL/UOPHELP

    mumki

    2015-01-01

    For more course tutorials visit www.uophelp.com IT 206 Week 1 CheckPoint Formatting Issues IT 206 Week 1 DQ 1 and DQ 2 IT 206 Week 2 CheckPoint Knowing Where You Placed Your Document IT 206 Week 2 Assignment Microsoft Word Exercise IT 206 Week 3 CheckPoint Simplifying Your Excel Usage IT 206 Week 3 DQ 1 and DQ 2 IT 206 Week 4 CheckPoint The Risk of Macros IT 206 Week 4 Assignment Microsoft Excel Exercise IT 206 Week 5 CheckPoint Mail Merging IT 206 ...

  16. IT 206 UOP COURSE TUTORIAL/ UOPHELP

    BHARGAVI

    2015-01-01

    For more course tutorials visit www.uophelp.com IT 206 Week 1 CheckPoint Formatting Issues IT 206 Week 1 DQ 1 and DQ 2 IT 206 Week 2 CheckPoint Knowing Where You Placed Your Document IT 206 Week 2 Assignment Microsoft Word Exercise IT 206 Week 3 CheckPoint Simplifying Your Excel Usage IT 206 Week 3 DQ 1 and DQ 2 IT 206 Week 4 CheckPoint The Risk of Macros IT 206 Week 4 Assignment Microsoft Excel Exercise IT 206 Week 5 CheckPoint Mail Merging IT 206 ...

  17. Analysis of the gamma spectra of the uranium, actinium, and thorium decay series

    Momeni, M.H.

    1981-09-01

    This report describes the identification of radionuclides in the uranium, actinium, and thorium series by analysis of gamma spectra in the energy range of 40 to 1400 keV. Energies and absolute efficiencies for each gamma line were measured by means of a high-resolution germanium detector and compared with those in the literature. A gamma spectroscopy method, which utilizes an on-line computer for deconvolution of spectra, search and identification of each line, and estimation of activity for each radionuclide, was used to analyze soil and uranium tailings, and ore.

  18. Analysis of the gamma spectra of the uranium, actinium, and thorium decay series

    This report describes the identification of radionuclides in the uranium, actinium, and thorium series by analysis of gamma spectra in the energy range of 40 to 1400 keV. Energies and absolute efficiencies for each gamma line were measured by means of a high-resolution germanium detector and compared with those in the literature. A gamma spectroscopy method, which utilizes an on-line computer for deconvolution of spectra, search and identification of each line, and estimation of activity for each radionuclide, was used to analyze soil and uranium tailings, and ore

  19. IT 206 UOP Course Tutorial / Tutorialoutlet

    dawan

    2015-01-01

    For more course tutorials visit www.tutorialoutlet.com   IT 206 Week 1 CheckPoint Formatting Issues IT 206 Week 1 DQ 1 and DQ 2 IT 206 Week 2 CheckPoint Knowing Where You Placed Your Document IT 206 Week 2 Assignment Microsoft Word Exercise IT 206 Week 3 CheckPoint Simplifying Your Excel Usage IT 206 Week 3 DQ 1 and DQ 2 IT 206 Week 4 CheckPoint The Risk of Macros IT 206 Week 4 Assignment Microsoft Excel Exercise IT 206 Week 5 CheckPoint Mail M...

  20. In-source laser spectroscopy developments at TRILIS—towards spectroscopy on actinium and scandium

    Resonance Ionization Laser Ion Sources (RILIS) have become a versatile tool for production and study of exotic nuclides at Isotope Separator On-Line (ISOL) facilities such as ISAC at TRIUMF. The recent development and addition of a grating tuned spectroscopy laser to the TRIUMF RILIS solid state laser system allows for wide range spectral scans to investigate atomic structures on short lived isotopes, e.g., those from the element actinium, produced in uranium targets at ISAC. In addition, development of new and improved laser ionization schemes for rare isotope production at ISAC is ongoing. Here spectroscopic studies on bound states, Rydberg states and autoionizing (AI) resonances on scandium using the existing off-line capabilities are reported. These results allowed to identify a suitable ionization scheme for scandium via excitation into an autoionizing state at 58,104 cm − 1 which has subsequently been used for ionization of on-line produced exotic scandium isotopes.

  1. 40 CFR 240.206 - Vectors.

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Vectors. 240.206 Section 240.206 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.206 Vectors....

  2. 40 CFR 59.206 - Variances.

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Variances. 59.206 Section 59.206... Compound Emission Standards for Consumer Products § 59.206 Variances. (a) Any regulated entity who cannot... control may apply in writing to the Administrator for a variance. The variance application shall...

  3. 24 CFR 206.37 - Credit standing.

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Credit standing. 206.37 Section 206... CONVERSION MORTGAGE INSURANCE Eligibility; Endorsement Eligible Mortgagors § 206.37 Credit standing. Each mortgagor must have a general credit standing satisfactory to the Secretary....

  4. 24 CFR 206.15 - Insurance.

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Insurance. 206.15 Section 206.15... MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES HOME EQUITY CONVERSION MORTGAGE INSURANCE Eligibility; Endorsement § 206.15 Insurance. Mortgages originated under...

  5. 48 CFR 1417.206 - Evaluation.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Evaluation. 1417.206 Section 1417.206 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Options 1417.206 Evaluation. The determination in FAR...

  6. 44 CFR 206.3 - Policy.

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Policy. 206.3 Section 206.3 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE General § 206.3 Policy. It is the policy of FEMA to...

  7. 44 CFR 206.341 - Policy.

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Policy. 206.341 Section 206... SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE Coastal Barrier Resources Act § 206.341 Policy. It shall be the policy of FEMA to achieve the goals of CBRA in carrying out disaster relief on units of...

  8. 40 CFR 91.206 - Trading.

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Trading. 91.206 Section 91.206... EMISSIONS FROM MARINE SPARK-IGNITION ENGINES Averaging, Banking, and Trading Provisions § 91.206 Trading. (a... manufacturers in trading. These credits must be used in the same averaging set as generated. (b) Credits...

  9. 40 CFR 89.206 - Trading.

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Trading. 89.206 Section 89.206... EMISSIONS FROM NEW AND IN-USE NONROAD COMPRESSION-IGNITION ENGINES Averaging, Banking, and Trading Provisions § 89.206 Trading. (a) Requirements for Tier 1 engines rated at or above 37 kW. (1) A...

  10. 40 CFR 90.206 - Trading.

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Trading. 90.206 Section 90.206... Trading Provisions § 90.206 Trading. (a) An engine manufacturer may exchange emission credits with other engine manufacturers in trading, subject to the trading restriction specified in § 90.207(c)(2)....

  11. 14 CFR 206.1 - Emergency transportation.

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Emergency transportation. 206.1 Section 206.1 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS... EXEMPTIONS § 206.1 Emergency transportation. Notwithstanding the provisions of section 41101 of the...

  12. 40 CFR 240.206-1 - Requirement.

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirement. 240.206-1 Section 240.206-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.206-1...

  13. 24 CFR 206.41 - Counseling.

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Counseling. 206.41 Section 206.41... CONVERSION MORTGAGE INSURANCE Eligibility; Endorsement Eligible Mortgagors § 206.41 Counseling. (a) List... receive counseling. (b) Information to be provided. A counselor must discuss with the mortgagor: (1)...

  14. Developments towards in-gas-jet laser spectroscopy studies of actinium isotopes at LISOL

    Raeder, S.; Bastin, B.; Block, M.; Creemers, P.; Delahaye, P.; Ferrer, R.; Fléchard, X.; Franchoo, S.; Ghys, L.; Gaffney, L. P.; Granados, C.; Heinke, R.; Hijazi, L.; Huyse, M.; Kron, T.; Kudryavtsev, Yu.; Laatiaoui, M.; Lecesne, N.; Luton, F.; Moore, I. D.; Martinez, Y.; Mogilevskiy, E.; Naubereit, P.; Piot, J.; Rothe, S.; Savajols, H.; Sels, S.; Sonnenschein, V.; Traykov, E.; Van Beveren, C.; Van den Bergh, P.; Van Duppen, P.; Wendt, K.; Zadvornaya, A.

    2016-06-01

    To study exotic nuclides at the borders of stability with laser ionization and spectroscopy techniques, highest efficiencies in combination with a high spectral resolution are required. These usually opposing requirements are reconciled by applying the in-gas-laser ionization and spectroscopy (IGLIS) technique in the supersonic gas jet produced by a de Laval nozzle installed at the exit of the stopping gas cell. Carrying out laser ionization in the low-temperature and low density supersonic gas jet eliminates pressure broadening, which will significantly improve the spectral resolution. This article presents the required modifications at the Leuven Isotope Separator On-Line (LISOL) facility that are needed for the first on-line studies of in-gas-jet laser spectroscopy. Different geometries for the gas outlet and extraction ion guides have been tested for their performance regarding the acceptance of laser ionized species as well as for their differential pumping capacities. The specifications and performance of the temporarily installed high repetition rate laser system, including a narrow bandwidth injection-locked Ti:sapphire laser, are discussed and first preliminary results on neutron-deficient actinium isotopes are presented indicating the high capability of this novel technique.

  15. 5 CFR 330.206 - Job consideration.

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Job consideration. 330.206 Section 330..., SELECTION, AND PLACEMENT (GENERAL) Reemployment Priority List (RPL) § 330.206 Job consideration. (a)(1) An... of an overseas duty tour in the agency rotation program. In this case, the employee may apply for...

  16. 31 CFR 206.9 - Charges.

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Charges. 206.9 Section 206.9 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY RECEIPTS,...

  17. 31 CFR 206.7 - Compliance.

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Compliance. 206.7 Section 206.7 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY RECEIPTS,...

  18. 31 CFR 206.8 - Appeals.

    2010-07-01

    ... Treasury, the Assistant Commissioner, Federal Finance, and the designated agency cash management official... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Appeals. 206.8 Section 206.8 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE,...

  19. 31 CFR 206.2 - Definitions.

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Definitions. 206.2 Section 206.2 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY RECEIPTS,...

  20. 9 CFR 205.206 - Farm products.

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Farm products. 205.206 Section 205.206 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE CLEAR TITLE-PROTECTION FOR PURCHASERS OF FARM...

  1. 44 CFR 206.362 - Responsibilities.

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Responsibilities. 206.362 Section 206.362 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... Responsibilities. (a) The local government shall submit the financial information required by FEMA in...

  2. 44 CFR 206.372 - Responsibilities.

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Responsibilities. 206.372 Section 206.372 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... Responsibilities. (a) The local government shall submit the financial information required by FEMA in...

  3. 5 CFR 842.206 - Involuntary retirement.

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Involuntary retirement. 842.206 Section... (CONTINUED) FEDERAL EMPLOYEES RETIREMENT SYSTEM-BASIC ANNUITY Eligibility § 842.206 Involuntary retirement... separates from the service involuntarily after completing 25 years of service, or after becoming age 50...

  4. 48 CFR 17.206 - Evaluation.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Evaluation. 17.206 Section... CONTRACT TYPES SPECIAL CONTRACTING METHODS Options 17.206 Evaluation. (a) In awarding the basic contract... officer need not evaluate offers for any option quantities when it is determined that evaluation would...

  5. 24 CFR 206.23 - Shared appreciation.

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Shared appreciation. 206.23 Section 206.23 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES HOME...

  6. 44 CFR 206.343 - Scope.

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Scope. 206.343 Section 206.343 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND... orientation which is unrelated to development is not subject to the requirements of these regulations....

  7. 44 CFR 206.204 - Project performance.

    2010-10-01

    ... accordance with 44 CFR 13.21, Payment. (c) Time limitations for completion of work—(1) Deadlines. The project... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Project performance. 206.204... § 206.204 Project performance. (a) General. This section describes the policies and...

  8. 5 CFR 430.206 - Planning performance.

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Planning performance. 430.206 Section 430.206 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERFORMANCE MANAGEMENT Performance Appraisal for General Schedule, Prevailing Rate, and Certain Other Employees §...

  9. 44 CFR 206.345 - Exceptions.

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Exceptions. 206.345 Section 206.345 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF..., and of the access thereto; (4) Repair of facilities for scientific research, including but not...

  10. 5 CFR 2606.206 - Fees.

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Fees. 2606.206 Section 2606.206 Administrative Personnel OFFICE OF GOVERNMENT ETHICS ORGANIZATION AND PROCEDURES PRIVACY ACT RULES Access to... estimated fee before the Office begins to process a new request. (iii) Interest charges. Interest charges...

  11. 24 CFR 235.206 - Substitute mortgagors.

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Substitute mortgagors. 235.206... MORTGAGE INSURANCE AND ASSISTANCE PAYMENTS FOR HOME OWNERSHIP AND PROJECT REHABILITATION Contract Rights and Obligations-Homes for Lower Income Families § 235.206 Substitute mortgagors. (a) Selling...

  12. z206sc_video_observations

    U.S. Geological Survey, Department of the Interior — This part of DS 781 presents video observations from cruise Z206SC for the Santa Barbara Channel region and beyond in southern California. The vector data file is...

  13. 9 CFR 206.3 - Monthly report.

    2010-01-01

    ... STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE SWINE CONTRACT LIBRARY § 206.3 Monthly report. (a) Do I need... accordance with section 251 of the Agricultural Marketing Act (7 U.S.C. 1636) and may be modified from...

  14. 9 CFR 206.1 - Definitions.

    2010-01-01

    ... STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE SWINE CONTRACT LIBRARY § 206.1 Definitions. The definitions... marketing meats or meat food products from swine in an unmanufactured form acting as a wholesale...

  15. Star Formation in Henize 206

    2004-01-01

    [figure removed for brevity, see original site] IRA-MIPS Composite [figure removed for brevity, see original site] Visible [figure removed for brevity, see original site] IRAC [figure removed for brevity, see original site] MIPS The LMC is a small satellite galaxy gravitationally bound to our own Milky Way. Yet the gravitational effects are tearing the companion to shreds in a long-playing drama of 'intergalactic cannibalism.' These disruptions lead to a recurring cycle of star birth and star death. Astronomers are particularly interested in the LMC because its fractional content of heavy metals is two to five times lower than is seen in our solar neighborhood. [In this context, 'heavy elements' refer to those elements not present in the primordial universe. Such elements as carbon, oxygen and others are produced by nucleosynthesis and are ejected into the interstellar medium via mass loss by stars, including supernova explosions.] As such, the LMC provides a nearby cosmic laboratory that may resemble the distant universe in its chemical composition. The primary Spitzer image, showing the wispy filamentary structure of Henize 206, is a four-color composite mosaic created by combining data from an infrared array camera (IRAC) at near-infrared wavelengths and the mid-infrared data from a multiband imaging photometer (MIPS). Blue represents invisible infrared light at wavelengths of 3.6 and 4.5 microns. Note that most of the stars in the field of view radiate primarily at these short infrared wavelengths. Cyan denotes emission at 5.8 microns, green depicts the 8.0 micron light, and red is used to trace the thermal emission from dust at 24 microns. The separate instrument images are included as insets to the main composite. An inclined ring of emission dominates the central and upper regions of the image. This delineates a bubble of hot, x-ray emitting gas that was blown into space when a massive star died in a supernova explosion millions of years ago. The shock waves

  16. 44 CFR 206.2 - Definitions.

    2010-10-01

    ... major disaster. (22) State: Any State of the United States, the District of Columbia, Puerto Rico, the... SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE General § 206.2 Definitions. (a) General. The.... Stafford Disaster Relief and Emergency Assistance Act, Public Law 93-288, as amended. (2)...

  17. 24 CFR 206.45 - Eligible properties.

    2010-04-01

    ... DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES HOME EQUITY CONVERSION MORTGAGE INSURANCE Eligibility; Endorsement Eligible Properties § 206.45 Eligible properties. (a... insurance for reverse mortgages is not available for reasonable rates in a State, then the Secretary...

  18. 32 CFR 206.2 - Eligibility.

    2010-07-01

    ... NATIONAL SECURITY EDUCATION PROGRAM (NSEP) GRANTS TO INSTITUTIONS OF HIGHER EDUCATION § 206.2 Eligibility. Any accredited U.S. institution of higher education, as defined by section 1201(a) of the Higher Education Act of 1965 (20 U.S.C. 1141(a)), may apply for and receive a grant. This includes 2- and...

  19. 44 CFR 206.365 - Loan administration.

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Loan administration. 206.365... administration. (a) Funding. (1) FEMA will disburse funds to the local government when requested, generally in... government shall submit a copy of its most recent financial report (if not submitted previously)...

  20. 44 CFR 206.375 - Loan administration.

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Loan administration. 206.375... administration. (a) Funding. (1) FEMA will disburse funds to the local government when requested, generally in... government shall submit a copy of its most recent financial report (if not submitted previously)...

  1. 44 CFR 206.151 - Food commodities.

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Food commodities. 206.151... Food commodities. (a) The Administrator will assure that adequate stocks of food will be ready and... section, the Administrator may direct the Secretary of Agriculture to purchase food commodities...

  2. 44 CFR 206.225 - Emergency work.

    2010-10-01

    ... HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE Public Assistance Eligibility § 206.225... economically eliminates the need for temporary housing. The work will be limited to that necessary for the... communications. Emergency communications necessary for the purpose of carrying out disaster relief functions...

  3. 44 CFR 206.366 - Loan cancellation.

    2010-10-01

    ... utilities for mobile homes used to meet disaster temporary housing requirements. (iii) Unreimbursed costs... HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE Community Disaster Loans § 206.366 Loan cancellation. (a) Policies. (1) FEMA shall cancel repayment of all or part of a Community Disaster Loan to...

  4. 44 CFR 206.376 - Loan cancellation.

    2010-10-01

    ... homes used to meet disaster temporary housing requirements. (iii) Unreimbursed costs required for police... HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE Community Disaster Loans § 206.376 Loan cancellation. (a) FEMA shall cancel repayment of all or part of a Special Community Disaster Loan to the...

  5. 5 CFR 352.206 - Expiration of reemployment rights.

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Expiration of reemployment rights. 352.206 Section 352.206 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS....206 Expiration of reemployment rights. Reemployment rights granted under a Letter of Authority...

  6. 42 CFR 438.206 - Availability of services.

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Availability of services. 438.206 Section 438.206... Standards § 438.206 Availability of services. (a) Basic rule. Each State must ensure that all services... whether the location provides physical access for Medicaid enrollees with disabilities. (2)...

  7. 48 CFR 206.304 - Approval of the justification.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Approval of the justification. 206.304 Section 206.304 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... Competition 206.304 Approval of the justification. (a)(4) The Under Secretary of Defense...

  8. 30 CFR 206.155 - Accounting for comparison.

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Accounting for comparison. 206.155 Section 206... MANAGEMENT PRODUCT VALUATION Federal Gas § 206.155 Accounting for comparison. (a) Except as provided in... subpart. (b) The requirement for accounting for comparison contained in the terms of leases will govern...

  9. 19 CFR 206.6 - Report to the President.

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Report to the President. 206.6 Section 206.6... RELIEF ACTIONS General § 206.6 Report to the President. (a) In general. The Commission will include in its report to the President the following: (1) The determination made and an explanation of the...

  10. 44 CFR 206.141 - Disaster unemployment assistance.

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Disaster unemployment assistance. 206.141 Section 206.141 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... § 206.141 Disaster unemployment assistance. The authority to implement the disaster...

  11. 30 CFR 206.150 - Purpose and scope.

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Purpose and scope. 206.150 Section 206.150 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT PRODUCT VALUATION Federal Gas § 206.150 Purpose and scope. (a) This subpart is applicable to all...

  12. 5 CFR 880.206 - Date of death.

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Date of death. 880.206 Section 880.206...) RETIREMENT AND INSURANCE BENEFITS DURING PERIODS OF UNEXPLAINED ABSENCE Procedures § 880.206 Date of death... OPM, the date of death of a missing annuitant who has been determined to be dead by an...

  13. 30 CFR 206.260 - Allocation of washed coal.

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Allocation of washed coal. 206.260 Section 206... MANAGEMENT PRODUCT VALUATION Federal Coal § 206.260 Allocation of washed coal. (a) When coal is subjected to washing, the washed coal must be allocated to the leases from which it was extracted. (b) When the...

  14. 30 CFR 206.459 - Allocation of washed coal.

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Allocation of washed coal. 206.459 Section 206... MANAGEMENT PRODUCT VALUATION Indian Coal § 206.459 Allocation of washed coal. (a) When coal is subjected to washing, the washed coal must be allocated to the leases from which it was extracted. (b) When the...

  15. 19 CFR 206.15 - Institution of investigation.

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Institution of investigation. 206.15 Section 206.15 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS... OF RELIEF ACTIONS Investigations Relating to Global Safeguard Actions § 206.15 Institution...

  16. 27 CFR 26.206 - Marking packages and cases.

    2010-04-01

    .... 26.206 Section 26.206 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU... Coming Into the United States From the Virgin Islands § 26.206 Marking packages and cases. The distiller... distiller, rectifier, or bottler shall plainly print, stamp, or stencil with durable coloring material,...

  17. 24 CFR 115.206 - Performance assessments; Performance standards.

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Performance assessments; Performance standards. 115.206 Section 115.206 Housing and Urban Development Regulations Relating to Housing... AGENCIES Certification of Substantially Equivalent Agencies § 115.206 Performance assessments;...

  18. 41 CFR 101-27.206-3 - Packaging.

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Packaging. 101-27.206-3 Section 101-27.206-3 Public Contracts and Property Management Federal Property Management Regulations...-Management of Shelf-Life Materials § 101-27.206-3 Packaging. To the extent feasible and economical,...

  19. Groundwater seepage from the Ranger uranium mine tailings dam: radioisotopes of radium, thorium and actinium. Supervising Scientist report 106

    Monitoring of bores near the Ranger uranium mine tailings dam has revealed deterioration in water quality in several bores since 1983. In a group of bores to the north of the dam, increases have been observed of up to 500 times for sulphate concentrations and of up to 5 times for 226Ra concentrations. Results are presented here of measurements of members of the uranium, thorium and actinium decay series in borewater samples collected between 1985 and 1993. In particular, measurements of all four naturally-occurring radium isotopes have been used in an investigation of the mechanism of radium concentration changes. For the most seepage-affected bores the major findings of the study include: 228Ra/226Ra 223Ra /226Ra and 224Ra/228Ra ratios all increased over the course of the study; barium concentrations show high seasonal variability, being lower in November than May, but strontium concentrations show a steady increase with time. Calculations show that the groundwater is probably saturated with respect to barite but not with respect to celestite or anglesite; sulphide concentrations are low in comparison with sulphate, and are higher in November than in May; and 227Ac concentrations have increased with time, but do not account for the high 223Ra/226Ra ratios. It is concluded on the basis of these observations that increases in Ra isotope concentrations observed in a number of seepage-affected bores arise from increases in salinity leading to desorption of radium from adsorption sites in the vicinity of the bore rather by direct transport of radium from the tailings. Increased salinity is also causing the observed increases in 227Ac and strontium concentrations, while formation of a barite solid phase in the groundwater is causing the removal of some radium from solution. This is the cause of the increasing radium isotope ratios noted above

  20. 48 CFR 32.206 - Solicitation provisions and contract clauses.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Solicitation provisions and contract clauses. 32.206 Section 32.206 Federal Acquisition Regulations System FEDERAL ACQUISITION...) of this section); (iii) Liquidation of those financing payments by delivery payments (see...

  1. 48 CFR 1809.206-70 - Small businesses.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Small businesses. 1809.206-70 Section 1809.206-70 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... status on a Qualified Products List (Mil-Bul-103) or the Qualified Manufacturers List...

  2. 31 CFR 206.4 - Collection and payment mechanisms.

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Collection and payment mechanisms. 206.4 Section 206.4 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL...

  3. 31 CFR 206.1 - Scope and application.

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Scope and application. 206.1 Section 206.1 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY RECEIPTS,...

  4. 31 CFR 206.5 - Collection and deposit procedure exceptions.

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Collection and deposit procedure exceptions. 206.5 Section 206.5 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF...

  5. 31 CFR 206.6 - Cash management planning and review.

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Cash management planning and review. 206.6 Section 206.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL...

  6. 31 CFR 206.3 - Billing policy and procedures.

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Billing policy and procedures. 206.3 Section 206.3 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY...

  7. 24 CFR 206.25 - Calculation of payments.

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Calculation of payments. 206.25 Section 206.25 Housing and Urban Development Regulations Relating to Housing and Urban Development... Calculation of payments. (a) Initial payment. At closing an initial payment shall be made by the mortgagee...

  8. Dicty_cDB: CFJ206 [Dicty_cDB

    Full Text Available CF (Link to library) CFJ206 (Link to dictyBase) - - - Contig-U15397-1 CFJ206E (Link to Original ... the protein, antisense polynucleotide thereof and antibody ... recognizing the protein. 74 4e-30 5 E24613 |E24613 ... the protein, antisense polynucleotide thereof and antibody ... recognizing the protein. 74 3e-29 5 AR310712 |AR31 ...

  9. 9 CFR 206.2 - Swine contract library.

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Swine contract library. 206.2 Section... STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE SWINE CONTRACT LIBRARY § 206.2 Swine contract library. (a) Do... swine contract library will be made available to the public? GIPSA will summarize the information it...

  10. 47 CFR 20.6 - CMRS spectrum aggregation limit.

    2010-10-01

    ...) regulated as CMRS (see 47 CFR 20.9) shall have an attributable interest in a total of more than 55 MHz of... 47 Telecommunication 2 2010-10-01 2010-10-01 false CMRS spectrum aggregation limit. 20.6 Section... COMMERCIAL MOBILE RADIO SERVICES § 20.6 CMRS spectrum aggregation limit. (a) Spectrum limitation. No...

  11. 12 CFR 206.5 - Capital levels of correspondents.

    2010-01-01

    ... standards. See, e.g. 12 CFR part 208, subpart D. (1) A total risk-based capital ratio, as defined in... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Capital levels of correspondents. 206.5 Section... LIMITATIONS ON INTERBANK LIABILITIES (REGULATION F) § 206.5 Capital levels of correspondents. (a)...

  12. 19 CFR 206.16 - Industry adjustment plan and commitments.

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Industry adjustment plan and commitments. 206.16... OF RELIEF ACTIONS Investigations Relating to Global Safeguard Actions § 206.16 Industry adjustment... determination, any firm in the domestic industry, certified or recognized union or group of workers in...

  13. 9 CFR 113.206 - Wart Vaccine, Killed Virus.

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Wart Vaccine, Killed Virus. 113.206... AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Killed Virus Vaccines § 113.206 Wart Vaccine, Killed Virus. Wart Vaccine, Killed Virus, shall be...

  14. 32 CFR 48.206 - Information regarding elections.

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Information regarding elections. 48.206 Section... AND CIVILIAN RETIRED SERVICEMAN'S FAMILY PROTECTION PLAN Election of Options § 48.206 Information regarding elections. (a) All members of the Reserve component who will have accumulated sufficient...

  15. 49 CFR 173.206 - Packaging requirements for chlorosilanes.

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Packaging requirements for chlorosilanes. 173.206...-GENERAL REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Non-bulk Packaging for Hazardous Materials Other Than Class 1 and Class 7 § 173.206 Packaging requirements for chlorosilanes. (a) When § 172.101 of...

  16. 30 CFR 206.265 - Value enhancement of marketable coal.

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Value enhancement of marketable coal. 206.265... MANAGEMENT PRODUCT VALUATION Federal Coal § 206.265 Value enhancement of marketable coal. If, prior to use, sale, or other disposition, the lessee enhances the value of coal after the coal has been placed...

  17. 30 CFR 206.464 - Value enhancement of marketable coal.

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Value enhancement of marketable coal. 206.464... MANAGEMENT PRODUCT VALUATION Indian Coal § 206.464 Value enhancement of marketable coal. If, prior to use, sale, or other disposition, the lessee enhances the value of coal after the coal has been placed...

  18. Dicty_cDB: CHQ206 [Dicty_cDB

    Full Text Available CH (Link to library) CHQ206 (Link to dictyBase) - - - Contig-U16298-1 | Contig-U16523-1 CHQ206P ... 2.10.25 Translated Amino Acid sequence qykffkylfif*tnt *yfh*lif*YFQIKMIPKKQKGFNGEPKSHQEIDRSQSPLKQRTN NNNYQ ... vfqqlvnlhtkwhf*lveqfsl mlrlny Frame C: qykffkylfif*tnt *yfh*lif*YFQIKMIPKKQKGFNGEPKSHQEIDRSQSPLKQRTN NNNYQ ...

  19. 27 CFR 25.206 - Removal of beer.

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Removal of beer. 25.206... OF THE TREASURY LIQUORS BEER Removals Without Payment of Tax Beer for Personal Or Family Use § 25.206 Removal of beer. Beer made under § 25.205 may be removed from the premises where made for personal...

  20. 49 CFR 24.206 - Eviction for cause.

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Eviction for cause. 24.206 Section 24.206 Transportation Office of the Secretary of Transportation UNIFORM RELOCATION ASSISTANCE AND REAL PROPERTY... cause. (a) Eviction for cause must conform to applicable State and local law. Any person who...

  1. 30 CFR 206.301 - Value basis for royalty computation.

    2010-07-01

    ... MANAGEMENT PRODUCT VALUATION Other Solid Minerals § 206.301 Value basis for royalty computation. (a) The... business arrangement between the lessee and a purchaser of some or all of the commodities produced from...

  2. 42 CFR 59.206 - Evaluation and grant award.

    2010-10-01

    ... PLANNING SERVICES Grants for Family Planning Service Training § 59.206 Evaluation and grant award. (a... family planning services; (2) The extent to which the training program promises to fulfill the family...) Development of a capability within family planning service projects to provide pre- and in-service training...

  3. 44 CFR 206.43 - Emergency support teams.

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Emergency support teams. 206... Emergency support teams. The Federal Coordinating Officer may activate emergency support teams, composed of... emergency. These emergency support teams assist the FCO in carrying out his/her responsibilities under...

  4. 44 CFR 206.16 - Audit and investigations.

    2010-10-01

    ... OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE General § 206.16 Audit and investigations. (a) Subject to the provisions of chapter 75 of title 31, United States Code, and 44 CFR part 13... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Audit and investigations....

  5. 32 CFR 206.4 - Proposal development and review.

    2010-07-01

    ...) MISCELLANEOUS NATIONAL SECURITY EDUCATION PROGRAM (NSEP) GRANTS TO INSTITUTIONS OF HIGHER EDUCATION § 206.4... administration in higher education but might also include representatives from the research, business, and... criteria developed in consultation with representatives from higher education, and provided to the...

  6. 31 CFR 800.206 - Convertible voting instrument.

    2010-07-01

    ..., AND TAKEOVERS BY FOREIGN PERSONS Definitions § 800.206 Convertible voting instrument. The term convertible voting instrument means a financial instrument that currently does not entitle its owner or holder... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Convertible voting instrument....

  7. 18 CFR 706.206 - Support of Council programs.

    2010-04-01

    ... EMPLOYEE RESPONSIBILITIES AND CONDUCT Conduct and Responsibilities of Employees § 706.206 Support of Council programs. (a) When a Council program is based on law or Executive order, every employee has a positive obligation to make it function as efficiently and economically as possible and to support it...

  8. 33 CFR 160.206 - Information required in an NOA.

    2010-07-01

    ... Form 1302) as described in 19 CFR 4.7 X X X (9) International Ship and Port Facility Code (ISPS) Notice... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Information required in an NOA... Conditions, and Certain Dangerous Cargos § 160.206 Information required in an NOA. (a) Each NOA must...

  9. 48 CFR 50.206 - Solicitation provisions and contract clause.

    2010-10-01

    ... REGULATION CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Support Anti-terrorism by Fostering Effective Technologies Act of 2002 50.206 Solicitation provisions and contract clause. (a) Insert the provision at 52.250-2, SAFETY Act Coverage Not Applicable, in solicitations if— (1) The...

  10. 5 CFR 734.206 - Participation in elections.

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Participation in elections. 734.206... in elections. An employee may: (a) Register and vote in any election; (b) Act as recorder, watcher, challenger, or similar officer at polling places; (c) Serve as an election judge or clerk, or in a...

  11. 5 CFR 551.206 - Administrative exemption criteria.

    2010-01-01

    ... PAY ADMINISTRATION UNDER THE FAIR LABOR STANDARDS ACT Exemptions and Exclusions § 551.206... performance of office or non-manual work directly related to the management or general business operations, as... employees on the team. An example is a lead auditor who oversees an audit team in an auditing agency and...

  12. 44 CFR 206.207 - Administrative and audit requirements.

    2010-10-01

    ... administrative requirements of 44 CFR parts 13 and 206; (H) Compliance with the audit requirements of 44 CFR part... in FEMA regulations at 44 CFR part 13 or OMB Circular A-110 as appropriate. (2) Federal audit. In accordance with 44 CFR part 13, FEMA may elect to conduct a Federal audit of the disaster assistance grant...

  13. 40 CFR 180.206 - Phorate; tolerances for residues.

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Phorate; tolerances for residues. 180... PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances § 180.206 Phorate; tolerances for residues. (a) General. Tolerances are established for the combined residues of...

  14. 30 CFR 206.62 - Does MMS protect information I provide?

    2010-07-01

    ... Section 206.62 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT PRODUCT VALUATION Indian Oil § 206.62 Does MMS protect information I provide? The MMS will keep... Interior, 43 CFR part 2....

  15. 30 CFR 206.108 - Does MMS protect information I provide?

    2010-07-01

    ... Section 206.108 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT PRODUCT VALUATION Federal Oil § 206.108 Does MMS protect information I provide? Certain... Interior at 43 CFR part 2....

  16. 76 FR 12274 - Special Conditions: Bell Helicopter Textron Canada Limited Model 206B and 206L Series Helicopters...

    2011-03-07

    ... 206L series helicopters with the noise certification requirements of 14 CFR part 36. The FAA issues... would include, for example, a slight reduction in safety margins or functional capabilities, a slight..., a significant reduction in safety margins or functional capabilities, a significant increase in...

  17. 50 CFR 226.206 - Critical habitat for the Southern Resident killer whale (Orcinus orca).

    2010-10-01

    ... killer whale (Orcinus orca). 226.206 Section 226.206 Wildlife and Fisheries NATIONAL MARINE FISHERIES... CRITICAL HABITAT § 226.206 Critical habitat for the Southern Resident killer whale (Orcinus orca). Critical habitat is designated for the Southern Resident killer whale as described in this section. The...

  18. 28 CFR 2.206 - Travel approval and transfers of supervision.

    2010-07-01

    ... supervision. 2.206 Section 2.206 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION... Supervised Releasees § 2.206 Travel approval and transfers of supervision. (a) A releasee's supervision officer may approve travel outside the district of supervision without approval of the Commission in...

  19. 30 CFR 206.59 - May I ask MMS for valuation guidance?

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false May I ask MMS for valuation guidance? 206.59 Section 206.59 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT PRODUCT VALUATION Indian Oil § 206.59 May I ask MMS for valuation guidance? You may ask MMS...

  20. 41 CFR 101-27.206-2 - Identification and shipping requirements.

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Identification and shipping requirements. 101-27.206-2 Section 101-27.206-2 Public Contracts and Property Management Federal...-INVENTORY MANAGEMENT 27.2-Management of Shelf-Life Materials § 101-27.206-2 Identification and...

  1. 30 CFR 206.176 - How do I perform accounting for comparison?

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I perform accounting for comparison? 206.176 Section 206.176 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT PRODUCT VALUATION Indian Gas § 206.176 How do I perform accounting for comparison?...

  2. 30 CFR 206.173 - How do I calculate the alternative methodology for dual accounting?

    2010-07-01

    ... for dual accounting? 206.173 Section 206.173 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT PRODUCT VALUATION Indian Gas § 206.173 How do I calculate the alternative methodology for dual accounting? (a) Electing a dual accounting method. (1) If you...

  3. 48 CFR 206.302-3 - Industrial mobilization; or engineering, development, or research capability.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Industrial mobilization; or engineering, development, or research capability. 206.302-3 Section 206.302-3 Federal Acquisition... COMPETITION REQUIREMENTS Other Than Full and Open Competition 206.302-3 Industrial mobilization;...

  4. 42 CFR 137.206 - Why does the IHS need this information?

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Why does the IHS need this information? 137.206 Section 137.206 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH... Status Reports § 137.206 Why does the IHS need this information? This information will be used to...

  5. 19 CFR 206.47 - Limited disclosure of certain confidential business information under administrative protective...

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Limited disclosure of certain confidential business information under administrative protective order. 206.47 Section 206.47 Customs Duties UNITED... Investigations for Relief From Market Disruption § 206.47 Limited disclosure of certain confidential...

  6. 19 CFR 206.66 - Limited disclosure of certain confidential business information under administrative protective...

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Limited disclosure of certain confidential business information under administrative protective order. 206.66 Section 206.66 Customs Duties UNITED... Investigations For Action in Response to Trade Diversion; Reviews of Action Taken § 206.66 Limited disclosure...

  7. 19 CFR 206.17 - Limited disclosure of certain confidential business information under administrative protective...

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Limited disclosure of certain confidential business information under administrative protective order. 206.17 Section 206.17 Customs Duties UNITED... Investigations Relating to Global Safeguard Actions § 206.17 Limited disclosure of certain confidential...

  8. 7 CFR 3560.206 - Conversion to Plan II (Interest Credit).

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Conversion to Plan II (Interest Credit). 3560.206 Section 3560.206 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Rents § 3560.206 Conversion to Plan II (Interest Credit). The...

  9. MicroRNA-1/206 Targets c-Met and Inhibits Rhabdomyosarcoma Development*

    Yan, Dongsheng; Dong, Xiang Da (Eric); Chen, Xiaoyan; Wang, Lihua; Lu, Chunjing; Wang, Jiao; Qu, Jia; Tu, Lili

    2009-01-01

    MicroRNAs (miRNAs) are endogenous short (∼22) nucleotide RNAs that regulate gene function by modification of target mRNAs. miRNA-1 (miR-1) and miRNA-206 (miR-206) are highly expressed in skeletal muscle. Due to the tissue-specific nature of miR-1/206 for skeletal muscles, we investigated the role of miR-1/206 in the development of rhabdomyosarcoma. Initially, we demonstrated that miR-1/206 expression was suppressed in rhabdomyosarcomas and found at very low levels in a rhabdomyosarcoma RD cel...

  10. The Clinical analyse of 206 patients of cerebral infarction (Abstract)

    Mai Mai; Ti Yi Ming; Ghen Bo

    2000-01-01

    This thesis make a summary and analyse to 206 patients of cerebral infarction. The morbidity of the age from 51 to 70 is thehighist in 206 patients. It is 75.3 % a mong the patient that hypertension is original. The frequently-occurring cerebral in farction patient are 36.8 % and it is the highist. Because our hospital have purchased CT machinery, we can early diagnose cerebral infarction and do dissolving thrombus in early time, controlling blood pressure, clearing away free radical, dehydrating, di lating cerebral blood vessel, recovering treat early and so on. It reduced the appear ing of conplication and the death rate and viability by oneselfare improved obvious lv.

  11. Completion report for Well Cluster ER-20-6

    NONE

    1998-02-01

    The Well Cluster ER-20-6 drilling and completion project was conducted during February, March, and April of 1996 in support of the Nevada Environmental Restoration Project at the Nevada Test Site (NTS), Nye County, Nevada. This project is part of the DOE`s Underground Test Area (UGTA) subproject at the NTS. The primary UGTA tasks include collecting geological, geophysical, and hydrological data from new and existing wells to define groundwater quality as well as pathways and rates of groundwater migration at the NTS. A program of drilling wells near the sites of selected underground nuclear tests (near-field drilling) was implemented as part of the UGTA subproject to obtain site-specific data on the nature and extent of migration of radionuclides produced by an underground nuclear explosion. The ER-20-6 near-field drilling project was originally planned to be very similar to that recently conducted at Well Cluster ER-20-5, which was designed to obtain data on the existing hydrologic regime near the site of an underground nuclear explosion (IT, 1995; IT, 1996a). However, after further consideration of the goals of the near-field drilling program and the characteristics of the BULLION site, the TWG recommended that the ER-20-6 project be redesigned to accommodate a forced-gradient experiment. This proposed experiment is expected to yield more realistic estimates of transport parameters than can be deduced from sampling and testing natural groundwater flow systems.

  12. Completion report for Well Cluster ER-20-6

    The Well Cluster ER-20-6 drilling and completion project was conducted during February, March, and April of 1996 in support of the Nevada Environmental Restoration Project at the Nevada Test Site (NTS), Nye County, Nevada. This project is part of the DOE's Underground Test Area (UGTA) subproject at the NTS. The primary UGTA tasks include collecting geological, geophysical, and hydrological data from new and existing wells to define groundwater quality as well as pathways and rates of groundwater migration at the NTS. A program of drilling wells near the sites of selected underground nuclear tests (near-field drilling) was implemented as part of the UGTA subproject to obtain site-specific data on the nature and extent of migration of radionuclides produced by an underground nuclear explosion. The ER-20-6 near-field drilling project was originally planned to be very similar to that recently conducted at Well Cluster ER-20-5, which was designed to obtain data on the existing hydrologic regime near the site of an underground nuclear explosion (IT, 1995; IT, 1996a). However, after further consideration of the goals of the near-field drilling program and the characteristics of the BULLION site, the TWG recommended that the ER-20-6 project be redesigned to accommodate a forced-gradient experiment. This proposed experiment is expected to yield more realistic estimates of transport parameters than can be deduced from sampling and testing natural groundwater flow systems

  13. Measurement of internal pairs from {sup 206}Pb

    Ahmad, I.; Back, B.B.; Betts, R.R. [and others

    1995-08-01

    The failure to observe sharp sum-energy lines in measurements of {sup 238}U + {sup 181}Ta and {sup 238}U + {sup 232}Th raises the issue of the correct functioning of APEX under in-beam conditions. Extensive measurements with electron and pair emitting sources were used to demonstrate the resolution and acceptance of APEX, but the possibility remains that some unforeseen background or other effects might compromise the ability to see peaks in-beam. In order to test the functioning of APEX under the most stringent conditions, we also performed a measurement of internal pairs produced in the decay of the 2.648-MeV 3{sup -} state in {sup 206}Pb to the 2{sup +} state at 0.803 MeV. The 3{sup -} state was excited in the {sup 206}Pb + {sup 206}Pb reaction at 5.9 MeV/u with a cross section of roughly 40 mb, resulting in an expected pair cross section of approximately 16 {mu}b. It should be emphasized that this measurement represents a much stricter test of the functioning of the apparatus than the observation of sum-energy lines would represent, as the internal pair measurement requires a Doppler shift correction before the transition can be seen. These data were analyzed and clearly show the expected peak. A Doppler-corrected sum-energy spectrum showing the expected IPC line at 823 keV. At present we are evaluating the acceptance of APEX for events of this type but it is clear that the observed yield is close to expectations.

  14. High enriched lead-206 for small nuclear power plants

    In modern projects of perspective NPP the preference is returned to fast reactors (FR) with heavy liquid metal coolants. Internal self-hardening, absence of poisoning effects, compensation of uranium fuel burn-out by produced plutonium fuel and other positive features of FR will allow in the long term to lengthen operating campaign of the reactor till 10-12 of years, and service life of FR - till 30-60 of years. As is known, the coolant, circulating through the core of FR, is activated and accumulates long-lived radionuclides. Taking in account the masses of coolant materials in considered FR (20-200 tons) and the scales of an introduction of small NPP in the future, it can be problems with handling a completed coolant after FR removal from exploitation and at realization of repair and emergency activities. There, it is desirable to have a low-activation coolant with low contents of long-lived radionuclides - products of nuclear reactions. In paper, presented at the ICONE-8 conference, it is offered to use lead enriched with isotope Pb-206 as a low-activation coolant for FR. Its contents in a natural mix of lead isotopes make 24 %, and the demanded enrichment of isotope does not exceed 95-98 %. However, usage of a coolant from enriched lead can result in advancing the price of power, owing to what NPP can become noncompetitive in relation to other power sources. The purpose of the present paper - to point that interval of the prices of the product lead-206, at which one it can be demanded for nuclear engineering in large quantities. In the paper possible ways to ease the costs of obtaining the product lead-206 for the need of small nuclear engineering are also considered. (author)

  15. La eximente de miedo insuperable (art. 20.6 CP)

    Varona Gómez, Daniel

    1999-01-01

    La te si doctoral tracte d' una causa d' exempció de la responsabilitat penal reconeguda a l'article 20.6 del vigent codi penal: la por insuperable. L' objectiu principal de la tesi és donar un contingut a aquesta eximent per tal de que trobi l'adient reconeixement als tribunals, que tradicionalment han ignorat aquesta eximent. El primer capítol de la tesi tracta del seu fonament, és a dir, de la raó o raons que han portat al legislador a reconèixer la por insuperable com a una causa de exemp...

  16. Experiments of analog states on Lead 206 and 207

    This research thesis aims at verifying hypotheses according to which the spread of analog states decreases as much as nuclei are far from a double magic nucleus, under some conditions. Therefore, analog states of lead 207 and 208 have been studied by proton scattering on targets in lead 206 and 207. Some theoretical aspects of analog states of isobaric spin are presented. An experimental method of determination of excitation functions is described. Results obtained for analog states in bismuth 207-208 are discussed. Results obtained on four steady lead isotopes in different laboratories are compared

  17. Nanoparticle-Induced Superior Hot Tearing Resistance of A206 Alloy

    Choi, Hongseok; Cho, Woo-hyun; Konishi, Hiromi; Kou, Sindo; Li, Xiaochun

    2013-04-01

    Al- Cu alloys (such as A206) offer high strength and high fracture toughness at both room and elevated temperatures. However, their widespread applications are limited because of their high susceptibility to hot tearing. This article presents a nanotechnology approach to enhance hot-tearing resistance for A206. Specifically, γ-Al2O3 nanoparticles were used, and their effects on the hot-tearing resistance of the as-cast Al-4.5Cu alloy (A206) were investigated. While it is well known that grain refinement can improve the hot-tearing resistance of cast Al alloys, the current study demonstrated that nanoparticles can be much more effective in the case of A206. The hot-tearing susceptibilities (HTSs) of A206 alloy and its Al2O3 nanocomposite were evaluated by constrained rod casting (CRC) with a steel mold. Monolithic A206 and M206 (the Ti-free version of A206) alloys with the B contents of 20, 40, and 300 ppm from an Al-5Ti-1B master alloy addition were also cast under the same conditions for comparison. The results showed that with an addition of 1 wt pct γ-Al2O3 nanoparticles, the extent of hot tearing in A206 alloys was markedly reduced to nearly that of A356, an Al-Si alloy highly resistant to hot tearing. As compared with grain-refined A206 or M206, the hot-tearing resistance of the nanocomposites was significantly better, even though the grain size was not reduced as much. Microstructural analysis suggested that γ-Al2O3 nanoparticles modified the solidification microstructure of the eutectic of θ-Al2Cu and α-Al, as well as refined primary grains, resulting in the enhancement of the hot-tearing resistance of A206 to a level similar to that of A356 alloy.

  18. Electron capture and positron decay of 206Fr and 208Fr and the energy levels of 206Rn and 208Rn

    The isotopes 206Fr and 208Fr were produced by the reactions Ir(20Ne,xn)/sup 206,208/Fr and mass separated on-line. The electron-capture and positron decays to 206Rn and 208Rn were studied by collecting γ ray and internal conversion electron singles spectra as a function of decay time as well as γ-γ, γ-e-, and γ-x ray coincidence spectra. The energies and many of the spins were determined for 18 excited, even parity states in 208Rn and for 10 excited, even parity states in 206Rn. These nuclei appear to be excellent candidates for interpretation in terms of a weak coupling shell model. The energy levels were also compared to the predictions of the interacting boson approximation model

  19. 44 CFR 206.253 - Insurance requirements for facilities damaged by disasters other than flood.

    2010-10-01

    ... facilities damaged by disasters other than flood. 206.253 Section 206.253 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER... by disasters other than flood. (a) Prior to approval of a Federal grant for the restoration of...

  20. Structural analysis and dimerization profile of the SCAN domain of the pluripotency factor Zfp206

    Liang, Yu

    2012-06-26

    Zfp206 (also named as Zscan10) belongs to the subfamily of C2H2 zinc finger transcription factors, which is characterized by the N-terminal SCAN domain. The SCAN domain mediates self-association and association between the members of SCAN family transcription factors, but the structural basis and selectivity determinants for complex formation is unknown. Zfp206 is important for maintaining the pluripotency of embryonic stem cells presumably by combinatorial assembly of itself or other SCAN family members on enhancer regions. To gain insights into the folding topology and selectivity determinants for SCAN dimerization, we solved the 1.85 crystal structure of the SCAN domain of Zfp206. In vitro binding studies using a panel of 20 SCAN proteins indicate that the SCAN domain Zfp206 can selectively associate with other members of SCAN family transcription factors. Deletion mutations showed that the N-terminal helix 1 is critical for heterodimerization. Double mutations and multiple mutations based on the Zfp206SCAN-Zfp110SCAN model suggested that domain swapped topology is a possible preference for Zfp206SCAN-Zfp110SCAN heterodimer. Together, we demonstrate that the Zfp206SCAN constitutes a protein module that enables C2H2 transcription factor dimerization in a highly selective manner using a domain-swapped interface architecture and identify novel partners for Zfp206 during embryonal development. 2012 The Author(s).

  1. 31 CFR 598.206 - Holding of funds in interest-bearing accounts; investment and reinvestment.

    2010-07-01

    ... a money market fund or in U.S. Treasury bills. (2) For purposes of this section, a rate is... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Holding of funds in interest-bearing accounts; investment and reinvestment. 598.206 Section 598.206 Money and Finance: Treasury...

  2. 15 CFR 2011.206 - Suspension or revocation of individual certificates.

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Suspension or revocation of individual certificates. 2011.206 Section 2011.206 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE ALLOCATION OF TARIFF-RATE QUOTA ON...

  3. 24 CFR 206.107 - Mortgagee election of assignment or shared premium option.

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Mortgagee election of assignment or shared premium option. 206.107 Section 206.107 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL...

  4. Downregulation of microRNA-206 promotes invasion and angiogenesis of triple negative breast cancer.

    Liang, Zhongxing; Bian, Xuehai; Shim, Hyunsuk

    2016-08-26

    Triple negative breast tumors don't respond to Tamoxifen and Herceptin, two of the most effective medications for treating breast cancer. Additionally, triple negative breast cancer (TNBC) intrinsically resists or will eventually acquire resistance to chemotherapy. The purpose of this study is to understand better the molecular basis of TNBC as well as develop new therapeutic strategies against it. Here, we analyzed miRNA-206 expression levels in breast cancer cell lines and tissues. In addition, we investigated whether miR-206 mimics inhibited TNBC tumor invasion and angiogenesis. The results showed that miR-206 was downregulated in TNBC compared to non-TNBC cell lines and tissues. Additionally, the decreased levels of miR-206 were inversely consistent with expression levels of VEGF. Furthermore, the forced expression of miR-206 in the mimic-transfected TNBC cells downregulated VEGF, MAPK3, and SOX9 expression levels. The miR-206 mimics inhibited TNBC breast cell invasion and angiogenesis. These findings demonstrate for the first time the involvement of miRNA-206 in TNBC invasion and angiogenesis and suggest that miR-206 may be an efficient agent for therapy of TNBC. PMID:27318091

  5. 10 CFR 431.206 - Energy conservation standards and their effective dates.

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Energy conservation standards and their effective dates. 431.206 Section 431.206 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT Illuminated Exit Signs Energy Conservation Standards §...

  6. 44 CFR 206.181 - Use of gifts and bequests for disaster assistance purposes.

    2010-10-01

    ...) Disaster-related home repair and rebuilding assistance to families for permanent housing purposes... disaster assistance purposes. 206.181 Section 206.181 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE...

  7. 41 CFR 101-27.206 - Procurement of shelf-life materials.

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Procurement of shelf-life materials. 101-27.206 Section 101-27.206 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT...

  8. 30 CFR 206.180 - How do I determine an actual processing allowance?

    2010-07-01

    ... under 30 CFR 218.54 from the first day of the first month you deducted a processing allowance until the... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I determine an actual processing allowance? 206.180 Section 206.180 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE...

  9. 9 CFR 93.206 - Declaration and other documents for poultry.

    2010-01-01

    ..., the name and address of the broker, the origin of the poultry, the number, breed, species, and purpose... poultry. 93.206 Section 93.206 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EXPORTATION AND IMPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL...

  10. Evaluation of complete neutron nuclear data for 206Pb

    The following neutron data are given for 206Pb in the energy range from 10-5 eV to 20.0 MeV. The evaluated neutron nuclear data included total, elastic , inelastic, total inelastic, inelastic cross sections to 15 discrete levels, inelastic continuum, (n,2n), (n,3n), (n,n'p), (n,p), (n,t), (n,α) and capture cross sections. The angular distributions of elastic and discrete in elastic scattering neutron, the double differential cross sections (DDCS) of secondary neutron, the gamma-ray production data and the resonance parameters are also included. The evaluated data will be adopted into CENDL-3 in ENDF/B-6 format

  11. 30 CFR 206.112 - What adjustments and transportation allowances apply when I value oil production from my lease...

    2010-07-01

    ... 206.112 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT PRODUCT VALUATION Federal Oil § 206.112 What adjustments and transportation allowances apply...

  12. 17 CFR 275.206(4)-4 - Financial and disciplinary information that investment advisers must disclose to clients.

    2010-04-01

    ... written disclosure statement to clients under Rule 204-3 (17 CFR 275.204-3); Provided, That the delivery... ADVISERS ACT OF 1940 § 275.206(4)-4 Financial and disciplinary information that investment advisers must... information that investment advisers must disclose to clients. 275.206(4)-4 Section 275.206(4)-4 Commodity...

  13. 30 CFR 206.110 - How do I determine a transportation allowance under an arm's-length transportation contract?

    2010-07-01

    ... under an arm's-length transportation contract? 206.110 Section 206.110 Mineral Resources MINERALS... § 206.110 How do I determine a transportation allowance under an arm's-length transportation contract? (a) If you or your affiliate incur transportation costs under an arm's-length transportation...

  14. 5 CFR 831.206 - Continuation of coverage for former Federal employees of the Civilian Marksmanship Program.

    2010-01-01

    ... Federal employees of the Civilian Marksmanship Program. 831.206 Section 831.206 Administrative Personnel... § 831.206 Continuation of coverage for former Federal employees of the Civilian Marksmanship Program. (a... support the Civilian Marksmanship Program as of the day before the date of the transfer of the Program...

  15. MiR-206在骨骼肌发育中的功能%Roles of miR-206 in skeletal muscle development

    马国达; 罗小暖; 韩冰; 李庆章

    2012-01-01

    MicroRNAs (miRNAs) are a class of highly conserved small non-coding RNAs of ~22-nucleotides involved in post-transcriptional gene silencing. The emerging field of miRNA biology has unraveled roles for these regulatory molecules in a range of biological functions, including cell proliferation, differentiation and apoptosis. Interestingly, many miRNAs are specifically expressed in muscles. In this review, we focus on miR-206 which is unique in that it is only expressed in skeletal muscle and has been shown to play an important role in myogenesis. Importantly, dysregulation of miR-206 has been linked to muscle-related diseases, such as Duchenne muscular dystrophy and amyotrophic lateral sclerosis. In addition, a mutation in the 3'-UTR of the myostatin gene in the Texel sheep creating target sites for the microRNAs miR-206 and miR-1 leads to down regulation of myostatin expression, which is likely to cause the muscular phenotype of this breed of sheep. Therefore, miR-206 may become a novel target in optimization of muscle quantity of domestic animals and therapy of muscle-related diseases.%微RNA (microRNA,miRNA)是一类在分子进化中十分保守的非编码RNA,长度约22个核苷酸,一般情况下它在转录后水平抑制基因表达.miRNA在细胞增殖、分化、凋亡等诸多生理过程中发挥着重要作用.有些miRNA具有组织特异性表达,其中miR-206是目前发现的唯一在骨骼肌中特异表达的miRNA,它在凋节骨骼肌发生过程中扮演重要角色.miR-206表达异常与一些肌肉相关疾病如肌肉营养不良、肌萎缩性侧索硬化症等有关.此外,在Texel羊中,myostatin基因的一个点突变就产生了一个miR-206和miR-1的靶点,抑制了myostain基因的表达,从而产生了双肌表型.因此,miR-206有可能成为治疗肌肉相关疾病和畜禽改良育种的重要候选分子.

  16. Fusion of 8He with 206Pb around Coulomb barrier energies

    Raabe R.

    2011-10-01

    Full Text Available The experimental study of the fusion of light neutron-rich nucleus 8He with 206Pb is reported in this work. A fusion stack of 206Pb targets has been used for this study. The most prominent evaporation residue (210Po, which has half-life of 138 days and decays by alpha emission, is populated in the reaction. Radiochemical analysis technique is used to extract the yield of this evaporation residue.

  17. 30 CFR 206.355 - How do I calculate royalty due on geothermal resources I sell at arm's length to a purchaser for...

    2010-07-01

    ... multiplied by the royalty rate in your lease or that BLM prescribes under 43 CFR 3211.18. See § 206.361 for... resources I sell at arm's length to a purchaser for direct use? 206.355 Section 206.355 Mineral Resources... Geothermal Resources § 206.355 How do I calculate royalty due on geothermal resources I sell at arm's...

  18. Neutron capture studies of 206Pb at a cold neutron beam

    Schillebeeckx, P.; Belgya, T.; Borella, A.; Kopecky, S.; Mengoni, A.; Quétel, C. R.; Szentmiklósi, L.; Trešl, I.; Wynants, R.

    2013-11-01

    Gamma-ray transitions following neutron capture in 206Pb have been studied at the cold neutron beam facility of the Budapest Neutron Centre using a metallic sample enriched in 206Pb and a natural lead nitrate powder pellet. The measurements were performed using a coaxial HPGe detector with Compton suppression. The observed -rays have been incorporated into a decay scheme for neutron capture in 206Pb . Partial capture cross sections for 206Pb(n,) at thermal energy have been derived relative to the cross section for the 1884keV transition after neutron capture in 14N . From the average crossing sum a total thermal neutron capture cross section of mb was derived for the 206Pb(n,) reaction. The thermal neutron capture cross section for 206Pb has been compared with contributions due to both direct capture and distant unbound s-wave resonances. From the same measurements a thermal neutron-induced capture cross section of mb was determined for the 207Pb(n,) reaction.

  19. Overexpression of miR-206 suppresses glycolysis, proliferation and migration in breast cancer cells via PFKFB3 targeting

    Ge, Xin; Lyu, Pengwei; Cao, Zhang; Li, Jingruo; Guo, Guangcheng; Xia, Wanjun; Gu, Yuanting, E-mail: zzyuantinggu@126.com

    2015-08-07

    miRNAs, sorting as non-coding RNAs, are differentially expressed in breast tumor and act as tumor promoters or suppressors. miR-206 could suppress the progression of breast cancer, the mechanism of which remains unclear. The study here was aimed to investigate the effect of miR-206 on human breast cancers. We found that miR-206 was down-regulated while one of its predicted targets, 6-Phosphofructo-2-kinase (PFKFB3) was up-regulated in human breast carcinomas. 17β-estradiol dose-dependently decreased miR-206 expression as well as enhanced PFKFB3 mRNA and protein expression in estrogen receptor α (ERα) positive breast cancer cells. Furthermore, we identified that miR-206 directly interacted with 3′-untranslated region (UTR) of PFKFB3 mRNA. miR-206 modulated PFKFB3 expression in MCF-7, T47D and SUM159 cells, which was influenced by 17β-estradiol depending on ERα expression. In addition, miR-206 overexpression impeded fructose-2,6-bisphosphate (F2,6BP) production, diminished lactate generation and reduced cell proliferation and migration in breast cancer cells. In conclusion, our study demonstrated that miR-206 regulated PFKFB3 expression in breast cancer cells, thereby stunting glycolysis, cell proliferation and migration. - Highlights: • miR-206 was down-regulated and PFKFB3 was up-regulated in human breast carcinomas. • 17β-estradiol regulated miR-206 and PFKFB3 expression in ERα+ cancer cells. • miR-206directly interacted with 3′-UTR of PFKFB3 mRNA. • miR-206 fructose-2,6-bisphosphate (F2,6BP) impeded production and lactate generation. • miR-206 reduced cell proliferation and migration in breast cancer cells.

  20. Overexpression of miR-206 suppresses glycolysis, proliferation and migration in breast cancer cells via PFKFB3 targeting

    miRNAs, sorting as non-coding RNAs, are differentially expressed in breast tumor and act as tumor promoters or suppressors. miR-206 could suppress the progression of breast cancer, the mechanism of which remains unclear. The study here was aimed to investigate the effect of miR-206 on human breast cancers. We found that miR-206 was down-regulated while one of its predicted targets, 6-Phosphofructo-2-kinase (PFKFB3) was up-regulated in human breast carcinomas. 17β-estradiol dose-dependently decreased miR-206 expression as well as enhanced PFKFB3 mRNA and protein expression in estrogen receptor α (ERα) positive breast cancer cells. Furthermore, we identified that miR-206 directly interacted with 3′-untranslated region (UTR) of PFKFB3 mRNA. miR-206 modulated PFKFB3 expression in MCF-7, T47D and SUM159 cells, which was influenced by 17β-estradiol depending on ERα expression. In addition, miR-206 overexpression impeded fructose-2,6-bisphosphate (F2,6BP) production, diminished lactate generation and reduced cell proliferation and migration in breast cancer cells. In conclusion, our study demonstrated that miR-206 regulated PFKFB3 expression in breast cancer cells, thereby stunting glycolysis, cell proliferation and migration. - Highlights: • miR-206 was down-regulated and PFKFB3 was up-regulated in human breast carcinomas. • 17β-estradiol regulated miR-206 and PFKFB3 expression in ERα+ cancer cells. • miR-206directly interacted with 3′-UTR of PFKFB3 mRNA. • miR-206 fructose-2,6-bisphosphate (F2,6BP) impeded production and lactate generation. • miR-206 reduced cell proliferation and migration in breast cancer cells

  1. Determination of the neutron resonance parameters for 206Pb and of the thermal neutron capture cross section for 206Pb and 209Bi

    Chapter 1 describes the motivation of the measurements (accelerator driven systems, stellar nucleosynthesis, neutron induced reactions on 206Pb), the present status of the neutron capture data for 206Pb and 209Bi and the structure of this work. In Chapter 2 the basic reaction theory underlying this work is described. The neutron induced reaction mechanism and formalism are explained. The parameterisation of the cross section in terms of R-matrix theory is discussed and we put particular emphasis on the statistical behaviour of the resonance parameters and the impact of the angular distribution of gamma rays following neutron capture. The relation between experimental observables and the resonance parameters is discussed together with general comments related to resonance shape analysis. Chapter 3 is focused on the determination of resonance parameters for 206Pb. We performed high-resolution transmission and capture measurements at the Time-Of-Flight (TOF) facility GELINA of the IRMM at Geel (B) and determined the resonance parameters. For nuclei like 206Pb, where the total width is dominated by Γn, the capture area allows to determine G. Transmission measurements were carried out to determine Γn, and the statistical factor g of resonances. Before performing a Resonance Shape Analysis (RSA) on the transmission and capture data, we verified the neutron flux and resolution at GELINA. We also compared the characteristics of GELINA with those of the n-TOF facility at CERN. A special emphasis is placed on the total energy detection technique using C6D6 detectors. This technique was applied for the determination of the capture cross section. To reduce systematic bias effects on the capture cross section, the response of the detectors was determined by Monte Carlo simulations, which has been validated by experiments. Using these response functions the partial capture cross sections for individual resonances of 206Pb have been deduced, by unfolding the response of the C6D

  2. Interplay among solidification, microstructure, residual strain and hot tearing in B206 aluminum alloy

    Hot tearing is a complex phenomenon attributed to alloy solidification, microstructure and stress/strain development within a casting. In this research, the conditions associated with the formation of hot tears in B206 aluminum alloy were investigated. Neutron diffraction strain mapping was carried out on three B206 castings with varying levels of titanium (i.e. unrefined, 0.02 and 0.05 wt%). Titanium additions effectively reduced grain size and transformed grain morphology from coarse dendrites to fine globular grains. Further, thermal analysis suggested that grain refinement delayed the onset of dendrite coherency in B206 and therefore enhanced the duration of bulk liquid metal feeding for the refined casting conditions. As a result, the interactive effects of such factors resulted in a more uniform distribution of strain, and subsequent higher resistance to hot tearing for the grain refined castings

  3. Source identification of Pb in aerosols at Jeju-do, Korea by using 207Pb/206Pb and 208Pb/206Pb

    Aerosols and source related materials (fly ash from refuse incinerators, vehicle exhaust and soil) were collected in April, 2002 in the northern areas of Jeju-do, Korea, and the Pb isotopic ratios (207Pb/206Pb and 208Pb/206Pb) of the samples were measured in order to estimate the Pb sources of the aerosols. The Pb isotopic ratios of the aerosols were classified into two groups, depending on the sampling date. One group showed similar Pb isotopic ratios with those of the source related materials, suggesting that the contribution of the regional sources to the aerosols was very large. The other showed different Pb isotopic ratios from those of the regional sources and relatively high Pb isotopic ratios compared to the ratios of the first group. The results suggest that in the continental Asia there seems to be a long range transport of Pb with high ratios in desert sands, which are carried by northwest seasonal winds.(author)

  4. Crystal optimization and preliminary diffraction data analysis of the SCAN domain of Zfp206

    Crystals of the SCAN domain of Zfp206 are tetragonal, belonging to space group I422 with unit-cell parameters a = 67.57, c = 87.54 Å and one molecule in the asymmetric unit, and diffract to 1.85 Å resolution. Zfp206 (also named Zscan10) is a transcription factor that plays an important role in maintaining the pluripotent state of embryonic stem cells. Zfp206 is a member of the SCAN-domain family of C2H2 zinc-finger transcription factors. The SCAN domain is a highly conserved motif of 84 residues which mediates the self-association of and heterodimerization between SCAN-domain family transcription factors. The SCAN domain may therefore be the key to the selective oligomerization of and may combinatorially enhance the regulatory versatility of C2H2 zinc fingers. This paper describes crystallization attempts with the SCAN domain of Zfp206 (Zfp206SCAN) and optimization strategies to obtain diffraction-quality crystals. The best diffracting crystal was grown in a solution consisting of 0.3 M ammonium sulfate, 0.1 M Tris–HCl pH 8.6, 25% PEG 3350, 0.1 M ethylenediaminetetraacetic acid disodium salt dehydrate (EDTA) using the hanging-drop vapour-diffusion technique. Optimized crystals diffracted to 1.85 Å resolution and belonged to space group I422, with unit-cell parameters a = 67.57, c = 87.54 Å. A Matthews analysis indicated the presence of one Zfp206SCAN molecule per asymmetric unit

  5. 30 CFR 206.103 - How do I value oil that is not sold under an arm's-length contract?

    2010-07-01

    ... arm's-length contract? 206.103 Section 206.103 Mineral Resources MINERALS MANAGEMENT SERVICE... oil that is not sold under an arm's-length contract? This section explains how to value oil that you... average of the gross proceeds accruing to the seller under your or your affiliates' arm's-length...

  6. 75 FR 69861 - Airworthiness Directives; Cessna Aircraft Company (Cessna) 172, 175, 177, 180, 182, 185, 206, 207...

    2010-11-16

    ....johnson@faa.gov . SUPPLEMENTARY INFORMATION: Airworthiness Directive 2008-26-10, Amendment 39-15776 (73 FR... Company (Cessna) 172, 175, 177, 180, 182, 185, 206, 207, 208, 210, 303, 336, and 337 Series Airplanes... obstruction is found for certain Cessna 172, 175, 177, 180, 182, 185, 206, 207, 208, 210, 303, 336, and...

  7. 41 CFR 101-42.206 - Special requirements for utilization of hazardous materials and certain categories of property.

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Special requirements for utilization of hazardous materials and certain categories of property. 101-42.206 Section 101-42.206 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS UTILIZATION...

  8. 25 CFR 161.206 - What must a permittee do to protect livestock from exposure to disease?

    2010-04-01

    ... exposure to disease? 161.206 Section 161.206 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR... permittee do to protect livestock from exposure to disease? In accordance with applicable law, permittees... infectious diseases; and (c) Restrict the movement of exposed or infected livestock....

  9. 34 CFR 206.1 - What are the special educational programs for students whose families are engaged in migrant and...

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false What are the special educational programs for students whose families are engaged in migrant and other seasonal farmwork? 206.1 Section 206.1 Education..., DEPARTMENT OF EDUCATION SPECIAL EDUCATIONAL PROGRAMS FOR STUDENTS WHOSE FAMILIES ARE ENGAGED IN MIGRANT...

  10. 26 CFR 601.206 - Certification required to obtain reduced foreign tax rates under income tax treaties.

    2010-04-01

    ... under income tax treaties. (a) Basis of certification. Most of the income tax treaties between the United States and foreign countries provide for either a reduction in the statutory rate of tax or an... foreign tax rates under income tax treaties. 601.206 Section 601.206 Internal Revenue INTERNAL...

  11. 42 CFR 456.206 - Organization and composition of UR committee; disqualification from UR committee membership.

    2010-10-01

    ... UTILIZATION CONTROL Utilization Control: Mental Hospitals Ur Plan: Administrative Requirements § 456.206... the diagnosis and treatment of mental diseases, and assisted by other professional personnel. (c) The UR committee must be constituted as— (1) A committee of the mental hospital staff; (2) A...

  12. 42 CFR 420.206 - Disclosure of persons having ownership, financial, or control interest.

    2010-10-01

    ... of Ownership and Control Information § 420.206 Disclosure of persons having ownership, financial, or... provide that information. (b) Time and manner of disclosure. (1) Any disclosing entity that is subject to... this section. (d) Public disclosure. Information furnished to the Secretary under the provisions...

  13. 31 CFR 206.10 - Operation of and payments from the Cash Management Improvements Fund.

    2010-07-01

    ... SERVICE MANAGEMENT OF FEDERAL AGENCY RECEIPTS, DISBURSEMENTS, AND OPERATION OF THE CASH MANAGEMENT IMPROVEMENTS FUND § 206.10 Operation of and payments from the Cash Management Improvements Fund. (a) The Cash... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Operation of and payments from...

  14. 49 CFR 236.206 - Battery or power supply with respect to relay; location.

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Battery or power supply with respect to relay..., AND APPLIANCES Automatic Block Signal Systems Standards § 236.206 Battery or power supply with respect to relay; location. The battery or power supply for each signal control relay circuit, where an...

  15. 9 CFR 381.206 - Labeling of shipping containers of poultry products offered for entry.

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Labeling of shipping containers of... Imported Poultry Products § 381.206 Labeling of shipping containers of poultry products offered for entry. Shipping containers of imported poultry products are required to bear in a prominent and legible manner...

  16. 30 CFR 206.350 - What is the purpose of this subpart?

    2010-07-01

    ... MANAGEMENT PRODUCT VALUATION Geothermal Resources § 206.350 What is the purpose of this subpart? (a) This subpart applies to all geothermal resources produced from Federal geothermal leases issued pursuant to the Geothermal Steam Act of 1970 (GSA), as amended by the Energy Policy Act of 2005 (EPAct) (30 U.S.C. 1001...

  17. 30 CFR 206.365 - Does MMS protect information I provide?

    2010-07-01

    ... Act regulations of the Department of the Interior at 43 CFR part 2. ... MANAGEMENT PRODUCT VALUATION Geothermal Resources § 206.365 Does MMS protect information I provide? Certain information you submit to MMS regarding royalties or fees on geothermal resources or byproducts,...

  18. 15 CFR 270.206 - Public briefings and requests for information.

    2010-01-01

    ... Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NATIONAL CONSTRUCTION SAFETY TEAMS NATIONAL CONSTRUCTION SAFETY TEAMS Investigations § 270.206 Public briefings and requests... progress of an investigation. Methods may include: (1) A public Web site; (2) Mailing lists, to include...

  19. 24 CFR 206.308 - Continuing education requirements of counselors listed on the HECM Counselor Roster.

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Continuing education requirements... LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES HOME EQUITY CONVERSION MORTGAGE INSURANCE HECM Counselor Roster § 206.308 Continuing education requirements of counselors...

  20. 44 CFR 206.34 - Request for utilization of Department of Defense (DOD) resources.

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Request for utilization of... The Declaration Process § 206.34 Request for utilization of Department of Defense (DOD) resources. (a... Assistance Directorate may direct DOD to utilize DOD personnel and equipment for removal of debris...

  1. 17 CFR 275.206(4)-1 - Advertisements by investment advisers.

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Advertisements by investment... COMMISSION (CONTINUED) RULES AND REGULATIONS, INVESTMENT ADVISERS ACT OF 1940 § 275.206(4)-1 Advertisements.... 80b-3), directly or indirectly, to publish, circulate, or distribute any advertisement: (1)...

  2. 40 CFR 141.206 - Notice to new billing units or new customers.

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Notice to new billing units or new... Water Violations § 141.206 Notice to new billing units or new customers. (a) What is the requirement for... public notice to all new billing units or new customers prior to or at the time service begins. (b)...

  3. 28 CFR 5.206 - Language and wording of registration statement.

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Language and wording of registration... OF FOREIGN AGENTS REGISTRATION ACT OF 1938, AS AMENDED § 5.206 Language and wording of registration... required to be filed under the Act shall be submitted in the English language. An exhibit may be filed...

  4. 34 CFR 403.206 - What are the State's responsibilities regarding a State occupational information coordinating...

    2010-07-01

    ... EDUCATION STATE VOCATIONAL AND APPLIED TECHNOLOGY EDUCATION PROGRAM What Are the Administrative Responsibilities of a State Under the State Vocational and Applied Technology Education Program? § 403.206 What are... 34 Education 3 2010-07-01 2010-07-01 false What are the State's responsibilities regarding a...

  5. 19 CFR 206.54 - Investigations with respect to extension of action.

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Investigations with respect to extension of action..., Modification, or Termination of Relief Action § 206.54 Investigations with respect to extension of action. (a... at any time during an investigation under this section with respect to an article that was...

  6. 42 CFR 50.206 - Sterilization of a mentally incompetent individual or of an institutionalized individual.

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Sterilization of a mentally incompetent individual..., DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS POLICIES OF GENERAL APPLICABILITY Sterilization of Persons in Federally Assisted Family Planning Projects § 50.206 Sterilization of a mentally incompetent individual...

  7. 40 CFR 266.206 - Standards applicable to the treatment and disposal of waste military munitions.

    2010-07-01

    ... HAZARDOUS WASTES AND SPECIFIC TYPES OF HAZARDOUS WASTE MANAGEMENT FACILITIES Military Munitions § 266.206 Standards applicable to the treatment and disposal of waste military munitions. The treatment and disposal of hazardous waste military munitions are subject to the applicable permitting, procedural,...

  8. 30 CFR 206.102 - How do I calculate royalty value for oil that I or my affiliate sell(s) under an arm's-length...

    2010-07-01

    ... or my affiliate sell(s) under an arm's-length contract? 206.102 Section 206.102 Mineral Resources... Federal Oil § 206.102 How do I calculate royalty value for oil that I or my affiliate sell(s) under an arm... seller under the arm's-length contract, less applicable allowances determined under §§ 206.110 or...

  9. microRNA-206对人横纹肌肉瘤细胞增殖的影响%Effect of microRNA-206 on proliferation of human rhabdomyosarcoma cells

    陈晓燕; 王教; 王瓯晨

    2009-01-01

    目的 研究microRNA-206在人横纹肌肉瘤细胞A673和A204中的表达以及对细胞增殖的影响.方法 Northern blotting检测正常肌肉组织与人横纹肌肉瘤细胞中microRNA-206表达水平的差异,MTS法检测转染microRNA-206后对细胞增殖的影响.Western blotting检测microRNA-206后对细胞中蛋白水平的影响.结果 Northern blotting结果显示,microRNA-206在正常肌肉组织中高表达,在横纹肌肉瘤细胞A673和A204中不表达;MTS结果表明转染microRNA-206后,横纹肌肉瘤细胞的数目明显减少,microRNA能够明显下调人横纹肌肉瘤细胞中p-ERK的表达.结论 microRNA-206通过ERK信号传导通路抑制横纹肌肉瘤细胞的增殖.

  10. MicroRNA-206 induces G1 arrest in melanoma by inhibition of CDK4 and Cyclin D.

    Georgantas, Robert W; Streicher, Katie; Luo, Xiaobing; Greenlees, Lydia; Zhu, Wei; Liu, Zheng; Brohawn, Philip; Morehouse, Christopher; Higgs, Brandon W; Richman, Laura; Jallal, Bahija; Yao, Yihong; Ranade, Koustubh

    2014-03-01

    Expression profiling of microRNAs in melanoma lesional skin biopsies compared with normal donor skin biopsies, as well as melanoma cell lines compared with normal melanocytes, revealed that hsa-miR-206 was down-regulated in melanoma (-75.4-fold, P = 1.7 × 10(-4)). MiR-206 has been implicated in a large number of cancers, including breast, lung, colorectal, ovarian, and prostate cancers; however, its role in tumor development remains largely unknown, its biologic function is poorly characterized, and its targets affecting cancer cells are largely unknown. MiR-206 reduced growth and migration/invasion of multiple melanoma cell lines. Bioinformatics identified cell cycle genes CDK2, CDK4, Cyclin C, and Cyclin D1 as strong candidate targets. Western blots and 3'UTR reporter gene assays revealed that miR-206 inhibited translation of CDK4, Cyclin D1, and Cyclin C. Additionally, hsa-miR-206 transfection induced G1 arrest in multiple melanoma cell lines. These observations support hsa-miR-206 as a tumor suppressor in melanoma and identify Cyclin C, Cyclin D1, and CDK4 as miR-206 targets. PMID:24289491

  11. NanoSIMS 207Pb-206Pb dating of monazite, xenotime and baddeleyite

    Verdel, C.; Mahan, K.; Guan, Y.; Eiler, J.; Wernicke, B.

    2007-12-01

    A variety of geochronological problems call for in-situ dating with high spatial resolution (i.e., scales of tens of microns or less). Such techniques are particularly important for studies that focus on the relationships between intracrystalline age variations and petrologic or diagenetic processes. Precise, in-situ geochronology of particularly small grains or domains (ca. 1-5 microns) may be feasible with the Cameca NanoSIMS ion microprobe, which has a spatial resolution as good as tens of nanometers and sufficient mass resolution at high transmission to be useful for geochronologic systems involving isotopes of trace elements. We have used the Cameca NanoSIMS 50L housed in the Caltech Microanalysis Center to determine 207Pb/206Pb ages of monazite, xenotime and baddeleyite standards ranging in age from ~500 to 2000 Ma. Initial efforts focused on Pb-Pb geochronology because it is analytically straightforward: Pb is ionized almost entirely to Pb+ and instrumental mass fractionation of Pb isotopes is negligible. We compare our results to previous age determinations made on these standards using TIMS, SHRIMP and electron microprobe techniques. Our NanoSIMS 207Pb/206Pb age of 2047±35 Ma (2σ) for a baddeleyite crystal from the Phalaborwa carbonatite overlaps with the previously determined TIMS and SHRIMP dates of ca. 2060 Ma. We measured an age of 1018±20 Ma on xenotime standard x6413, slightly older than the TIMS 207Pb/206Pb date of 996.7±0.8 Ma. For the high-Th Moacyr monazite standard, variations of common-Pb corrected ages and 206Pb/204Pb ratios for 5 measurements spanning ~100 microns suggest varying amounts of interference from a mass-204 isobar (probably doubly ionized ThNdO2). The single measurement least-affected by this isobar corresponds to a common-Pb corrected 207Pb/206Pb age of 489±92 Ma, within error of the electron microprobe chemical age of ca. 505 Ma. Spatial variation of the mass-204 isobar intensity suggests that Th may be distributed

  12. 基于FSL206MR的离线式开关电源设计%Design of offline switch mode power based on FSL206MR

    汤永科; 王勇; 王小亮; 秦磊

    2014-01-01

    The paper introduces a design of offline switch mode power based on the power supply chip FSL206MR which integrates pulse width modulator(PWM)and SenseFET. It analyzes the working process and design program of the feedback circuit and buck topology in detail. The feedback network is composed of NPN transistor MMBT222A and voltage regulator diode BZX84C13. This switch mode power performs well and has many advantages, such as the simple structure, a good result of voltage stabilization and easy encapsulation, so it has the very high value in application.%介绍了一种基于集成 PWM 和 SenseFET 的开关电源芯片 FSL206MR 的离线式开关电源设计,详细分析了反馈电路和降压拓扑的工作过程及设计方案。采用 NPN 晶体三极管 MMBT2222A 和稳压管 BZX84C13组成反馈网络。该开关电源性能优良,具有结构简单、稳压效果好、易封装等优点,具有很高的生产应用价值。

  13. Coulomb excitation of the two proton-hole nucleus $^{206}$Hg

    We propose to use Coulomb excitation of the single magic two-proton-hole nucleus $^{206}$Hg. In a single-step excitation both the first 2$^{+}$ and the highly collective octupole 3$^{-}$ states will be populated. Thus, information on both quadrupole and octupole collectivity will be gained in this neutron-rich nucleus. Due to the high beam intensity, we will be able to observe multi-step Coulomb excitation as well, providing further test on theoretical calculations. The results will be used to improve the predictive power of the shell model for more exotic nuclei as we move to lighter N=126 nuclei. The experiment will use the new HIE-ISOLDE facility and the MINIBALL array, and will take advantage of the recently developed $^{206}$Hg beam from the molten lead target.

  14. Photolysis of organic pollutants in wastewater with 206 nm UV irradiation

    Zhao Lian Ye; Chang Qing Cao; Jin Cong He; Ren Xi Zhang; Hui Qi Hou

    2009-01-01

    A new-type UV light source (206 nm) was explored for the degradation of organic pollutants in wastewater for the first time. The degradation performances of triphenyltin chloride (TPTC1), dimethyl phthalate (DMP), as well as rhodamine B (RhB) were investigated. The results indicated that removal efficiency of 50 mg/L RhB, 60 mg/L DMP and 120 mg/LTPTC1 can reach 88.6%,92.5% and 89.4% for 60 min, 50 min and 75 min, respectively. By comparison of removal efficiency, we found 206 nm is superior to 253.7 nm UV in wastewater treatment, implying it is an effective, promising, and worthwhile exploring technology to decompose organic pollutants in wastewater.

  15. Radiochemical separation of carrier free 204,206Bi from α-irradiated thallium oxide target

    Carrier-free 204,206Bi produced by the α-activation of Tl2O3 target, was separated from the target matrix using two different radiochemical methods, (i) liquid-liquid extraction (LLX) with methyl isobutyl ketone (MIBK)-HCl system and (ii) solid-liquid extraction with inorganic ion exchanger, zirconium vanadate from HCl medium. The separation was found to be maximum around pH 2. (author)

  16. Distribution of charge and matter in nuclei: Charge density difference of 206Pb and 205Tl

    We contrast two calculations of the charge density difference of 206Pb and 205Tl. In the simplest model this difference in charge density is due to the occupation of an additional 3s/sub 1/2/ orbital in 206Pb. A standard mean-field calculation of the charge difference does not yield a satisfactory result. One may modify this result by assigning the 3s/sub 1/2/ orbital an occupation probability of seventy percent, with a corresponding increase to thirty percent of the occupation probability of a 2d/sub 3/2/ orbital. However, this modification of the mean-field analysis, while solving one problem, is seen to create a new problem in the fit to the data. In this work we present an alternative analysis: We maintain unit occupation probability for the 3s/sub 1/2/ orbital but use the medium-modified proton electromagnetic form factor we have calculated previously. Our model is able to give a better fit to the data without the introduction of free parameters into the analysis. Medium-modified form factors have recently been shown to be effective in explaining the charge distribution of 208Pb and their application to the interpretation of the 206Pb-205Tl charge density difference yields a result which is consistent with the experimental data and superior to that obtained in the adjusted mean-field analysis described above

  17. Frequency and Clinicopathological Characteristics of Presenilin 1 Gly206Ala Mutation in Puerto Rican Hispanics with Dementia

    Arnold, Steven E.; Vega, Irving E.; Karlawish, Jason H.; WoIk, David A.; Nunez, Jessica; Negron, Mirna; Xie, Sharon X.; Wang, Li-San; Dubroff, Jacob G.; McCarty-Wood, Elisabeth; Trojanowski, John Q.; Van Deerlin, Vivianna

    2013-01-01

    The frequency and clinical and pathological characteristics associated with the Gly206Ala presenilin 1 (PSEN1) mutation in Puerto Rican and non-Puerto Rican Hispanics were evaluated at the University of Pennsylvania’s Alzheimer’s Disease Center. DNAs from all cohort subjects were genotyped for the Gly206Ala PSEN1 mutation. Carriers and non-carriers with neurodegenerative disease dementias were compared for demographic, clinical, psychometric, and biomarker variables. Nineteen (12.6%) of 151 u...

  18. miR-206-3p在小鼠皮肤中的表达及其作用%Expression and distribution of miR-206-3p in mouse skin and its potential roles

    穆原; 周红; 李文艳; 李耀武

    2013-01-01

    Objective To investigate the expression and distribution of miR-206-3p and its target gene Bdnf (brain-derived neurotrophic factor) in mouse skin and the potential roles during the development of skin.Methods The full-thickness back skins of BALB/c mice on the 13.5 dpc (day post coition),15.5 dpc,17.5 dpc,1 dpp (day post partum),4 dpp and 16 weeks were collected respectively.The expression levels of miR-206-3p and BdnfmRNA were measured by real time RT-PCR,and BDNF protein was detected by western blot.The distributions of miR-206-3p and BDNF in tissue were profiled by in situ hybridization (ISH) and immunohistochemistry (IHC) respectively.Results The expression level of miR-206-3p increased gradually until 17.5 dpc and subsequently receded to the similar level of the 13.5 dpc during adult stage.The expression of BDNF protein exhibited in the opposite manner of miR-206-3p but BdnfmRNA remained stable from the 17.5 dpc until adult stage.ISH results showed that the distribution of miR-206-3p was gradually regionalized during the development of skin in the postnatal days and mainly located in the suprabasal layer and periphery of hair follicles,which was adjacent to the regions of BDNF expression at the same stage in a nonoverlapping manner.Conclusion The miR-206-3p may be involved in neurodevelopment of mouse skin through the post-transcriptional regulation of Bdnf.%目的 对小鼠皮肤中miR-206-3p及其靶基因脑源性神经营养因子(Bdnf)进行表达与定位检测,以探讨其在皮肤发育过程中的可能作用.方法 手术剪取13.5 dpc(交配后天数)、15.5 dpc、17.5 dpc胎鼠,1 dpp(出生后天数)、4 dpp乳鼠及16周龄雄鼠的背部全层皮肤,用实时荧光定量RT-PCR检测miR-206-3p与Bdnf mRNA的表达水平,western blot检测BDNF蛋白质表达水平,原位杂交与免疫组化分别检测miR-206-3p与BDNF的组织定位.结果 皮肤中miR-206-3p在胚胎期持续升高,到17.5 dpc后逐渐降低,于成年鼠时回复至13.5 dpc时

  19. A multi-frequency study of the peculiar interacting system Arp 206

    Arp 206 is a nearby, relatively large, and bright interacting system comprising unequal members: NGC 3432 and UGC 5983. A third anonymous galaxy, Arp 206c, is visible in the field. The CCD images show a well-developed bridge between NGC 3432 and UGC 5983. On the other hand, the complex H I tails are not visible in the optical. In the total H I map, the bridge is lost in a general envelope encompassing both galaxies. The bridge also appears to have some radio emission. On the Total H I map the system is rather edge-on, far more than it would appear in optical wavelengths. UGC 5983 falls exactly in line with NGC 3432. The velocity of the centers of mass of NGC 3432 and UGC 5983 are 530 km s(exp -1) and 630 km s(exp -1), respectively. In view of the considerable damage sustained by NGC 3432 and the apparent low mass of UGC 5983, it appears that the passage must have been at near parabolic speed, with a small pericentric distance and a very low inclination with rspect to the disk of NGC 3432. The apparent distribution of H I along the z axis of the galaxy could be accounted for by projection effects. The tidal appendage found at higher velocities, which rises at a P.A. approx. equal to 25 degrees west of the main body of the galaxy is probably the tail, the part of the tidal damage away from the perturbing companion. The bridge may be rising north-east from the galaxy and then continue under to the south of the galaxy. The relative sizes of the appendages would indicate that the pericenter was crossed recently. Any further inferences about the collision parameters will need to await the results of detailed computational modelling of the interaction. The authors also summarize the observational characteristics of NGC 3432, UGC 5983, and Arp 206c

  20. Coulomb excitation of re-accelerated 208Rn and 206Po beams

    In the present study, B(E2; 2+ → 0+) values have been measured in the 208Rn and 206Po nuclei through Coulomb excitation of re-accelerated radioactive beams in inverse kinematics at CERN-ISOLDE. The resulting B(E2; 2+ → 0+) in 208Rn is ∼ 0.08 e2b2. These nuclei lie in, or at the boundary of the region where seniority scheme should persist. However, contributions from collective excitations may be present when moving away from the N = 126 shell closure. To date, surprisingly little is known of the transition probabilities between the low-spin states in this region. (authors)

  1. Higgs Candidates in $e^+ e^-$ Interactions at $\\sqrt{s}$= 206.6 GeV

    Acciarri, M; Adriani, O; Aguilar-Benítez, M; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Ambrosi, G; Anderhub, H; Andreev, V P; Angelescu, T; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Bajo, A; Baksay, L; Balandras, A; Baldew, S V; Todorova-Nová, S; Banerjee, Sw; Barczyk, A; Barillère, R; Bartalini, P; Basile, M; Batalova, N; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Bellucci, L; Berbeco, R; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Bhattacharya, S; Biasini, M; Biland, A; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böhm, A; Boldizsar, L; Borgia, B; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brochu, F; Buffini, A; Buijs, A; Burger, J D; Burger, W J; Cai, X D; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Castellini, G; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada-Canales, M; Cesaroni, F; Chamizo-Llatas, M; Chang, Y H; Chaturvedi, U K; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chiefari, G; Cifarelli, Luisa; Cindolo, F; Civinini, C; Clare, I; Clare, R; Coignet, G; Colino, N; Costantini, S; Cotorobai, F; de la Cruz, B; Csilling, Akos; Cucciarelli, S; Dai, T S; van Dalen, J A; D'Alessandro, R; De Asmundis, R; Déglon, P L; Degré, A; Deiters, K; Della Volpe, D; Delmeire, E; Denes, P; De Notaristefani, F; De Salvo, A; Diemoz, M; Dierckxsens, M; Van Dierendonck, D N; Dionisi, C; Dittmar, Michael; Dominguez, A; Doria, A; Dova, M T; Duchesneau, D; Dufournaud, D; Duinker, P; Durán, I; El-Mamouni, H; Engler, A; Eppling, F J; Erné, F C; Ewers, A; Extermann, Pierre; Fabre, M; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Ferguson, T; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisk, I; Forconi, G; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gau, S S; Gentile, S; Gheordanescu, N; Giagu, S; Gong, Z F; Grenier, G; Grimm, O; Grünewald, M W; Guida, M; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hasan, A; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hidas, P; Hirschfelder, J; Hofer, H; Holzner, G; Hoorani, H; Hou, S R; Hu, Y; Iashvili, I; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Khan, R A; Käfer, D; Kaur, M; Kienzle-Focacci, M N; Kim, D; Kim, J K; Kirkby, Jasper; Kiss, D; Kittel, E W; Klimentov, A; König, A C; Kopal, M; Kopp, A; Koutsenko, V F; Kräber, M H; Krämer, R W; Krenz, W; Krüger, A; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Lee, H J; Le Goff, J M; Leiste, R; Levchenko, P M; Li Chuan; Likhoded, S A; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lü, Y S; Lübelsmeyer, K; Luci, C; Luckey, D; Lugnier, L; Luminari, L; Lustermann, W; Ma Wen Gan; Maity, M; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Mans, J; Marian, G; Martin, J P; Marzano, F; Mazumdar, K; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Von der Mey, M; Mihul, A; Milcent, H; Mirabelli, G; Mnich, J; Mohanty, G B; Moulik, T; Muanza, G S; Muijs, A J M; Musicar, B; Musy, M; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Niessen, T; Nisati, A; Nowak, H; Ofierzynski, R A; Organtini, G; Oulianov, A; Palomares, C; Pandoulas, D; Paoletti, S; Paolucci, P; Paramatti, R; Park, H K; Park, I H; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Pedace, M; Pensotti, S; Perret-Gallix, D; Petersen, B; Piccolo, D; Pierella, F; Pieri, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Postema, H; Pothier, J; Prokofiev, D O; Prokofev, D; Quartieri, J; Rahal-Callot, G; Rahaman, M A; Raics, P; Raja, N; Ramelli, R; Rancoita, P G; Ranieri, R; Raspereza, A V; Raven, G; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Riemann, S; Riles, K; Rodin, J; Roe, B P; Romero, L; Rosca, A; Rosier-Lees, S; Roth, S; Rosenbleck, C; Rubio, Juan Antonio; Ruggiero, G; Rykaczewski, H; Saremi, S; Sarkar, S; Salicio, J; Sánchez, E; Sanders, M P; Schäfer, C; Shchegelskii, V; Schmidt-Kärst, S; Schmitz, D; Schopper, Herwig Franz; Schotanus, D J; Schwering, G; Sciacca, C; Seganti, A; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shumilov, E; Shvorob, A V; Siedenburg, T; Son, D; Smith, B; Spillantini, P; Steuer, M; Stickland, D P; Stone, A; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z; Sushkov, S V; Suter, H; Swain, J D; Szillási, Z; Sztaricskai, T; Tang, X W; Tauscher, Ludwig; Taylor, L; Tellili, B; Timmermans, C; Ting, Samuel C C; Ting, S M; Tonwar, S C; Tóth, J; Tully, C; Tung, K L; Uchida, Y; Ulbricht, J; Valente, E; Vesztergombi, G; Vetlitskii, I; Vicinanza, D; Viertel, Gert M; Villa, S; Vivargent, M; Vlachos, S; Vodopyanov, I; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Vorvolakos, A; Wadhwa, M; Wallraff, W; Wang, M; Wang, X L; Wang, Z M; Weber, A; Weber, M; Wienemann, P; Wilkens, H; Wu, S X; Wynhoff, S; Xia, L; Xu, Z Z; Yamamoto, J; Yang, B Z; Yang, C G; Yang, H J; Yang, M; Ye, J B; Yeh, S C; Zalite, A; Zalite, Yu; Zhang, Z P; Zhu, G Y; Zhu, R Y; Zichichi, A; Zilizi, G; Zimmermann, B; Zöller, M

    2000-01-01

    In a search for the Standard Model Higgs boson, carried out on 212.5~$\\mathrm{pb^{-1}}$ of data collected by the L3 detector at the highest LEP centre-of-mass energies, including 116.5~$\\mathrm{pb^{-1}}$ above $\\sqrt{s} = 206$~GeV, an excess of candidates for the process $e^+ e^- \\rightarrow Z^{*}\\rightarrow HZ$ is found for Higgs masses near 114.5~GeV. We present an analysis of our data and the characteristics of our strongest candidates.

  2. Mechanism of Regulatory Effect of MicroRNA-206 on Connexin 43 in Distant Metastasis of Breast Cancer

    Zi-Jing Lin; Jia Ming; Lu Yang; Jun-Ze Du; Ning Wang; Hao-Jun Luo

    2016-01-01

    Background: MicroRNA-206 (miR-206) and connexin 43 (Cx43) are related with the distant metastasis of breast cancer.It remains unclear whether the regulatory effect of miR-206 on Cx43 is involved in metastasis of breast cancer.Methods: Using quantitative real-time polymerase chain reaction and Western blot, the expressions of miR-206 and Cx43 were determined in breast cancer tissues, hepatic and pulmonary metastasis (PM), and cell lines (MCF-10A, MCF-7, and MDA-MB-231).MCF-7/MDA-M-231 cells were transfected with lentivirus-shRNA vectors to enhance/inhibit miR-206, and then Cx43 expression was observed.Cell counting kit-8 assay and Transwell method were used to detect their changes in proliferation, migration, and invasion activity.The mutant plasmids of Cx43-3' untranslated region (3'UTR) at position 478-484 and position 1609-1615 were constructed.Luciferase reporter assay was performed to observe the effects of miR-206 on luciferase expression of different mutant plasmids and to confirm the potential binding sites of Cx43.Results: Cx43 protein expression in hepatic and PM was significantly higher than that in the primary tumor, while no significant difference was showed in messenger RNA (mRNA) expression.MiR-206 mRNA expression in hepatic and PM was significantly lower than that in the primary tumor.Cx43 mRNA and protein levels, as well as cell proliferation, migration, and invasion capabilities, were all significantly improved in MDA-MB-231 cells after reducing miR-206 expression but decreased in MCF-7 cells after elevating miR-206 expression, which demonstrated a significantly negative correlation between miR-206 and Cx43 expression (P =0.03).MiR-206 can drastically decrease Cx43 expression of MCF-7 cells but exerts no effects on Cx43 expression in 293 cells transfected with the Cx43 coding region but the lack of Cx43-3'UTR, suggesting that Cx43-3'UTR may be the key in Cx43 regulated by miR-206.Luciferase expression showed that the inhibition efficiency was

  3. Processing and geologic analysis of conventional cores from well ER-20-6 No. 1, Nevada Test Site

    Prothro, L.B., Townsend, M.J.; Drellack, S.L. Jr. [and others

    1997-09-01

    In 1996, Well Cluster ER-20-6 was drilled on Pahute Mesa in Area 20, in the northwestern corner of the Nevada Test Site (NTS). The three wells of the cluster are located from 166 to 296 meters (m) (544 to 971 feet [ft]) southwest of the site of the underground nuclear test code-named BULLION, conducted in 1990 in Emplacement Hole U-20bd. The well cluster was planned to be the site of a forced-gradient experiment designed to investigate radionuclide transport in groundwater. To obtain additional information on the occurrence of radionuclides, nature of fractures, and lithology, a portion of Well ER-20-6 No. 1, the hole closest to the explosion cavity, was cored for later analysis. Bechtel Nevada (BN) geologists originally prepared the geologic interpretation of the Well Cluster ER-20-6 site and documented the geology of each well in the cluster. However, the cores from Well ER-20-6 No. 1 were not accessible at the time of that work. As the forced-gradient experiment and other radio nuclide migration studies associated with the well cluster progressed, it was deemed appropriate to open the cores, describe the geology, and re-package the core for long-term air-tight storage. This report documents and describes the processing, geologic analysis, and preservation of the conventional cores from Well ER20-6 No. 1.

  4. Processing and geologic analysis of conventional cores from well ER-20-6 No. 1, Nevada Test Site

    In 1996, Well Cluster ER-20-6 was drilled on Pahute Mesa in Area 20, in the northwestern corner of the Nevada Test Site (NTS). The three wells of the cluster are located from 166 to 296 meters (m) (544 to 971 feet [ft]) southwest of the site of the underground nuclear test code-named BULLION, conducted in 1990 in Emplacement Hole U-20bd. The well cluster was planned to be the site of a forced-gradient experiment designed to investigate radionuclide transport in groundwater. To obtain additional information on the occurrence of radionuclides, nature of fractures, and lithology, a portion of Well ER-20-6 No. 1, the hole closest to the explosion cavity, was cored for later analysis. Bechtel Nevada (BN) geologists originally prepared the geologic interpretation of the Well Cluster ER-20-6 site and documented the geology of each well in the cluster. However, the cores from Well ER-20-6 No. 1 were not accessible at the time of that work. As the forced-gradient experiment and other radio nuclide migration studies associated with the well cluster progressed, it was deemed appropriate to open the cores, describe the geology, and re-package the core for long-term air-tight storage. This report documents and describes the processing, geologic analysis, and preservation of the conventional cores from Well ER20-6 No. 1

  5. Fatores que influenciaram a evolução de 206 pacientes com traumatismo craniencefálico grave Relevant factors in 206 patients with severe head injury

    Venâncio Pereira Dantas Filho

    2004-06-01

    Full Text Available A busca de fatores prognósticos para o traumatismo craniencefálico (TCE tem sido alvo de muitos estudos nas últimas décadas. A identificação de indicadores consistentes da evolução destes pacientes tem representado um grande desafio e sua utilidade considerada evidente tanto para orientar o tratamento, quanto para a estimativa do resultado final. Baseados numa casuística de 206 pacientes com TCE grave (8 pontos ou menos pela Escala de Coma de Glasgow - ECG, estudamos a influência de vários fatores sobre a evolução dos pacientes. A gravidade inicial medida pela ECG, a presença de hipertensão intracraniana (níveis acima de 20 mmHg, o tipo de lesão intracraniana e a presença de hipoxia, hipotensão arterial e a associação de hipóxia e hipotensão arterial tiveram influência significativa sobre a evolução dos pacientes. A presença de politraumatismo (pelo menos dois sítios de lesão além do TCE e a idade (acima e abaixo de 40 anos não influenciaram significativamente a evolução dos pacientes desta casuística.The search for head injury prognostic factors has been intense in the last decades. The importance of identification of these factors has been also recognised to treatment orientation and results estimatives. Based on 206 severe head injuried patients series, we analized the influence of factors over the outcome. The initial severity by Glasgow coma scale, the presence of intracranial hypertension (over 20 mmHg, the type of intracranial lesion and the presence of hypoxia, systemic hypotension or both, significantly influenced the results. The presence of multiple traumas (at least two sites of lesion over head injury, as age, did not influence the final results in this series.

  6. COL Application Content Guide for HTGRs: Revision to RG 1.206, Part 1 - Status Report

    Wayne Moe

    2012-08-01

    A combined license (COL) application is required by the Nuclear Regulatory Commission (NRC) for all proposed nuclear plants. The information requirements for a COL application are set forth in 10 CFR 52.79, “Contents of Applications; Technical Information in Final Safety Analysis Report.” An applicant for a modular high temperature gas-cooled reactor (HTGR) must develop and submit for NRC review and approval a COL application which conforms to these requirements. The technical information necessary to allow NRC staff to evaluate a COL application and resolve all safety issues related to a proposed nuclear plant is detailed and comprehensive. To this, Regulatory Guide (RG) 1.206, “Combined License Applications for Nuclear Power Plants” (LWR Edition), was developed to assist light water reactor (LWR) applicants in incorporating and effectively formatting required information for COL application review (Ref. 1). However, the guidance prescribed in RG 1.206 presumes a LWR design proposal consistent with the systems and functions associated with large LWR power plants currently operating under NRC license.

  7. $^{206}$ Po sources for production and release studies relevant for high power spallation targets

    The knowledge of the evaporation behaviour of Po is of essential importance for several scientific and technological applications, like accelerator driven systems (ADS) or the LIEBE project at CERN-ISOLDE. Fundamental investigations on the experimental conditions for the formation of volatile Po species as well as on the chemical composition of the volatile compounds are necessary for a safe operation of such facilities. $^{206}$Po, a mainly $\\gamma$- ray-emitting Po isotope with a half-life of 8.8 d, is best suited for model studies, due to the lower radiation hazard compared to the longer-lived $\\alpha$-emitting isotopes $^{208-210}$Po as well as the easy-tomeasure $\\gamma$-ray emission. We propose the production of $^{206}$Po samples in several matrices via the implantation of its precursor $^{210}$Fr into selected metal foils at CERN-ISOLDE. Using these samples, experiments will be carried out at PSI studying the volatilization of Po from different matrices under varying chemical conditions.

  8. Ocular Effects Of Laser Radiation From 1.06 to 2.06μ

    Stuck, Bruce E.; Lund, David J.; Beatrice, Edwin S.

    1980-10-01

    Ocular dose-response relationships were experimentally determined by ophthalmoscopy and biomicroscopy for selected exposure conditions at the following laser wavelengths: 1.064 μ (neodymium), 1.318 μ and 1.338 μ (neodymium), 1.54 μ (erbium), and 2.06 μ (holmium). The ocular responses were observed in Rhesus monkey eyes. Corneal effects were produced at 1.3 μ, 1.54 μ, and 2.06 μ, and no retinal or lenticular effects were observed for the conditions tested. Both the dose required to produce a minimal corneal lesion and the depth of the response exhibit a wavelength dependence. The corneal damage thresholds were indicative of the relative absorption properties of the cornea. These results suggest that current permissible exposure limits for wavelengths in this region should be elevated to reflect the relative absorption properties of the ocular media. The 1.3 μ neodymium laser appears to offer an advantage in ocular safety, an important consideration in system applications.

  9. Measurement of the radiative neutron capture cross section of 206Pb and its astrophysical implications

    Domingo-Pardo, C; Aerts, G; Alvarez, H; Alvarez-Velarde, F; Andriamonje, Samuel A; Andrzejewski, J; Assimakopoulos, Panayiotis; Audouin, L; Badurek, G; Baumann, P; Becvar, F; Berthoumieux, E; Bisterzo, S; Calviño, F; Calviani, M; Cano-Ott, D; Capote, R; Carrapico, C; Cennini, P; Chepel, V; Chiaveri, Enrico; Colonna, N; Cortés, G; Couture, A; Cox, J; Dahlfors, M; David, S; Dillman, I; Dolfini, R; Dridi, W; Durán, I; Eleftheriadis, C; Embid-Segura, M; Ferrant, L; Ferrari, A; Ferreira-Marques, R; Fitzpatrick, L; Frais-Kölbl, H; Fujii, K; Furman, W; Gallino, R; Gonçalves, I; Gonzalez-Romero, E; Goverdovski, A; Gramegna, F; Griesmayer, E; Guerrero, C; Gunsing, F; Haas, B; Haight, R; Heil, M; Herrera-Martínez, A; Igashira, M; Isaev, M; Jericha, E; Kappeler, F; Kadi, Y; Karadimos, D; Karamanis, D; Kerveno, M; Ketlerov, V; Köhler, P; Konovalov, V; Kossionides, E; Krticka, M; Lamboudis, C; Leeb, H; Lindote, A; Lopes, I; Lozano, M; Lukic, S; Marganiec, J; Marrone, S; Massimi, C; Mastinu, P; Mengoni, A; Milazzo, P M; Moreau, C; Mosconi, M; Neves, F; Oberhummer, Heinz; Oshima, M; O'Brien, S; Pancin, J; Papachristodoulou, C; Papadopoulos, C; Paradela, C; Patronis, N; Pavlik, A; Pavlopoulos, P; Perrot, L; Plag, R; Plompen, A; Plukis, A; Poch, A; Pretel, C; Quesada, J; Rauscher, T; Reifarth, R; Rosetti, M; Rubbia, Carlo; Rudolf, G; Rullhusen, P; Salgado, J; Sarchiapone, L; Savvidis, I; Stéphan, C; Tagliente, G; Taín, J L; Tassan-Got, L; Tavora, L; Terlizzi, R; Vannini, G; Vaz, P; Ventura, A; Villamarín, D; Vincente, M C; Vlachoudis, V; Vlastou, R; Voss, F; Walter, S; Wendler, H; Wiescher, M; Wisshak, K

    2007-01-01

    The (n, gamma) cross section of 206Pb has been measured at the CERN n_TOF facility with high resolution in the energy range from 1 eV to 600 keV by using two optimized C6D6 detectors. In the investigated energy interval about 130 resonances could be observed, from which 61 had enough statistics to be reliably analyzed via the R-matrix analysis code SAMMY. Experimental uncertainties were minimized, in particular with respect to (i) angular distribution effects of the prompt capture gamma-rays, and to (ii) the TOF-dependent background due to sample-scattered neutrons. Other background components were addressed by background measurements with an enriched 208Pb sample. The effect of the lower energy cutoff in the pulse height spectra of the C6D6 detectors was carefully corrected via Monte Carlo simulations. Compared to previous 206Pb values, the Maxwellian averaged capture cross sections derived from these data are about 20% and 9% lower at thermal energies of 5 keV and 30 keV, respectively. These new results hav...

  10. YOUNG STELLAR OBJECTS IN THE LARGE MAGELLANIC CLOUD STAR-FORMING REGION N206

    We present analysis of the energetic star-forming region Henize 206 (N206) located near the southern edge of the Large Magellanic Cloud (LMC) based on photometric data from the Spitzer Surveying the Agents of Galaxy Evolution (SAGE-LMC; IRAC 3.6, 4.5, 5.8, 8.0 μm and MIPS 24 μm), Infrared Survey Facility near-infrared survey (J, H, Ks ), and the Magellanic Clouds Photometric Survey (MCPS UBVI) covering a wavelength range of 0.36-24 μm. Young stellar object (YSO) candidates are identified based upon their location in infrared color-magnitude space and classified by the shapes of their spectral energy distributions in comparison with a pre-computed grid of YSO models. We identify 116 YSO candidates: 102 are well characterized by the YSO models, predominately Stage I, and 14 may be multiple sources or young sources with transition disks. Careful examination of the individual sources and their surrounding environment allows us to identify a factor of ∼14.5 more YSO candidates than have already been identified. The total mass of these well-fit YSO candidates is ∼520 Msun. We calculate a current star formation rate of 0.27 x 10-1 Msun yr-1 kpc-2. The distribution of YSO candidates appears to follow shells of neutral material in the interstellar medium.

  11. A novel missense (M206K STAT3 mutation in diffuse large B cell lymphoma deregulates STAT3 signaling.

    Guangzhen Hu

    Full Text Available Persistent STAT3 activation has been found in activated B-cell like diffuse large B cell tumors (DLBCL. To investigate whether genetic mutations play a role in aberrant STAT3 signaling in DLBCL, we bi-directionally sequenced all 24 exons of the STAT3 gene in DLBCL tumors (n = 40. We identified 2 novel point mutations in 2 separate (2/40; 5% patients at exon 7 and 24. Point mutation 2552G>A was a silent mutation in the stop codon. Another heterozygous mutation 857T>A encoded a methionine substitution by lysine at codon 206 (M206K in the coiled-coil domain of STAT3. We performed site directed mutagenesis to mutate wild type (WT STAT3α and STAT3β at codon 206 and constructed stable cell lines by lentiviral transfection of STAT3α(WT, STAT3α(M206K, STAT3β(WT and STAT3β(M206K plasmids. The mutation was found to increase STAT3 phosphorylation in STAT3α mutant cell lines with no effect on the STAT3β mutant cell line. Transcriptional activation was also increased in the STAT3α mutant cells compared with STAT3α WT cells as detected by a luciferase reporter assay. Moreover, STAT3α(M206K mutant cells were resistant to JAK2 pathway inhibition compared to STAT3α WT cells. These results indicate that missense mutations in STAT3 increase signaling through the JAK/STAT pathway. JAK2 inhibitors may be useful in the patient with this STAT3 mutation as well as those with pathway activation by other mechanisms.

  12. miR-206 Represses Hypertrophy of Myogenic Cells but Not Muscle Fibers via Inhibition of HDAC4

    Winbanks, Catherine E.; Beyer, Claudia; Hagg, Adam; Qian, Hongwei; Sepulveda, Patricio V.; Gregorevic, Paul

    2013-01-01

    microRNAs regulate the development of myogenic progenitors, and the formation of skeletal muscle fibers. However, the role miRNAs play in controlling the growth and adaptation of post-mitotic musculature is less clear. Here, we show that inhibition of the established pro-myogenic regulator miR-206 can promote hypertrophy and increased protein synthesis in post-mitotic cells of the myogenic lineage. We have previously demonstrated that histone deacetylase 4 (HDAC4) is a target of miR-206 in th...

  13. Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients

    Angelini Corrado

    2010-05-01

    Full Text Available Abstract Background MicroRNAs are highly conserved, noncoding RNAs involved in post-transcriptional gene silencing. They have been shown to participate in a wide range of biological processes, including myogenesis and muscle regeneration. The goal of this study is to test the hypothesis that myo-miRs (myo = muscle + miR = miRNA expression is altered in muscle from patients affected by myotonic dystrophy type 1 (DM1, the most frequently inherited neuromuscular disease in adults. In order to gain better insights about the role of miRNAs in the DM1 pathogenesis, we have also analyzed the muscular expression of miR-103 and miR-107, which have been identified in silico as attractive candidates for binding to the DMPK mRNA. Methods To this aim, we have profiled the expression of miR-133 (miR-133a, miR-133b, miR-1, miR-181 (miR-181a, miR-181b, miR-181c and miR-206, that are specifically induced during myogenesis in cardiac and skeletal muscle tissues. miR-103 and miR-107, highly expressed in brain, heart and muscle have also been included in this study. QRT-PCR experiments have been performed on RNA from vastus lateralis biopsies of DM1 patients (n = 7 and control subjects (n = 4. Results of miRNAs expression have been confirmed by Northern blot, whereas in situ hybridization technique have been performed to localize misexpressed miRNAs on muscle sections from DM1 and control individuals. Results Only miR-206 showed an over-expression in 5 of 7 DM1 patients (threshold = 2, fold change between 1.20 and 13.22, average = 5.37 compared to the control group. This result has been further confirmed by Northern blot analysis (3.37-fold overexpression, R2 = 0.89. In situ hybridization localized miR-206 to nuclear site both in normal and DM1 tissues. Cellular distribution in DM1 tissues includes also the nuclear regions of centralized nuclei, with a strong signal corresponding to nuclear clumps. Conclusions This work provides, for the first time, evidences about

  14. 30 CFR 206.111 - How do I determine a transportation allowance if I do not have an arm's-length transportation...

    2010-07-01

    ... if I do not have an arm's-length transportation contract or arm's-length tariff? 206.111 Section 206... have an arm's-length transportation contract or arm's-length tariff? (a) This section applies if you or your affiliate do not have an arm's-length transportation contract, including situations where you...

  15. 30 CFR 206.53 - How do I determine value for oil that I or my affiliate do(es) not sell under an arm's-length...

    2010-07-01

    ... affiliate do(es) not sell under an arm's-length contract? 206.53 Section 206.53 Mineral Resources MINERALS....53 How do I determine value for oil that I or my affiliate do(es) not sell under an arm's-length contract? (a) The unit value of your oil not sold under an arm's-length contract is the...

  16. 18 CFR Appendix I to Subpart F of... - Procedures for Compliance With the Endangered Species Act of 1973 Under § 157.206(b)(3)(i)

    2010-04-01

    ... CFR 402.02. The certificate holder shall be deemed in compliance with § 157.206(b)(2)(vi) of the... appropriate) as determined pursuant to 50 CFR 402.01 for the purpose of initiating informal consultations. 2... Compliance With the Endangered Species Act of 1973 Under § 157.206(b)(3)(i) I Appendix I to Subpart F...

  17. 40 CFR 600.206-08 - Calculation and use of FTP-based and HFET-based fuel economy values for vehicle configurations.

    2010-07-01

    ... HFET-based fuel economy values for vehicle configurations. 600.206-08 Section 600.206-08 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) ENERGY POLICY FUEL ECONOMY AND CARBON-RELATED EXHAUST EMISSIONS OF MOTOR VEHICLES Fuel Economy Regulations for 1977 and Later Model Year...

  18. 40 CFR 600.206-12 - Calculation and use of FTP-based and HFET-based fuel economy and carbon-related exhaust emission...

    2010-07-01

    ... HFET-based fuel economy and carbon-related exhaust emission values for vehicle configurations. 600.206-12 Section 600.206-12 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) ENERGY POLICY FUEL ECONOMY AND CARBON-RELATED EXHAUST EMISSIONS OF MOTOR VEHICLES Fuel Economy Regulations...

  19. 30 CFR 206.181 - How do I establish processing costs for dual accounting purposes when I do not process the gas?

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I establish processing costs for dual accounting purposes when I do not process the gas? 206.181 Section 206.181 Mineral Resources MINERALS... be deemed to be denied and subject to appeal to the MMS Director under 30 CFR part 290....

  20. miR-206 is down-regulated in breast cancer and inhibits cell proliferation through the up-regulation of cyclinD2

    Zhou, Jing, E-mail: zhougjing9888@163.com [Department of Oncology, Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu (China); Tian, Ye, E-mail: tianye2010077@163.com [Department of Hepatobiliary Surgery, Affiliated Yijishan Hospital of Wannan Medical College, Wuhu, Anhui (China); Li, Juan, E-mail: 402310848@163.com [Department of Oncology, Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu (China); Lu, Binbin, E-mail: lubin1976@163.com [Department of Oncology, Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu (China); Sun, Ming, E-mail: 422825636@qq.com [Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, Jiangsu (China); Zou, Yanfen, E-mail: 569111165@qq.com [Department of Obstetrics and Gynaecology, Jiangsu Province Hospital, Nanjing, Jiangsu (China); Kong, Rong, E-mail: 31815857@qq.com [Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, Jiangsu (China); Luo, Yanhong, E-mail: 252376737@qq.com [School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu (China); Shi, Yongguo, E-mail: 12071018@qq.com [Department of Oncology, Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu (China); Wang, Keming, E-mail: Tianyr1@163.com [Department of Oncology, Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu (China); Ji, Guozhong, E-mail: 252376737@qq.com [Department of Oncology, Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu (China)

    2013-04-05

    Highlights: ► miR-206 was downexpressed in tumor samples compared with matched normal samples. ► Enhanced expression of miR-206 could inhibit breast cancer growth in vitro. ► Luciferase confirmed miR-206 functions as an anti-oncogene by targeting cyclinD2. ► A reverse correlation between miR-206 and cyclinD2 in breast cancer was found. -- Abstract: MicroRNAs act as important gene regulators in human genomes, and their aberrant expression is linked to many malignancies. Aberrant expression of miR-206 has been frequently reported in cancer studies; however, the role and mechanism of its function in breast cancer remains unclear. Quantitative real-time PCR was performed to detect the relative expression levels of miR-206 in breast cancer and normal breast tissues. Lower expression of miR-206 in breast cancer tissues was associated with larger tumour size and a more advanced clinical stage. Further in vitro observations showed that the enforced expression of miR-206 in MCF-7 breast cancer cells inhibited cell growth by blocking the G1/S transition and suppressed cell proliferation and colony formation, implying that miR-206 functions as a tumour suppressor in the progression of breast cancer. Interestingly, Luciferase assays first revealed that miR-206 inhibited cyclinD2 expression by targeting two binding sites in the 3′-untranslated region of cyclinD2 mRNA. qRT-PCR and Western blot assays verified that miR-206 reduced cyclinD2 expression at both the mRNA and protein levels. A reverse correlation between miR-206 and cyclinD2 expression was noted in breast cancer tissues. Altogether, our results identify a crucial tumour suppressive role of miR-206 in the progression of breast cancer, at least partly via up-regulation of the expression of cyclinD2, and suggest that miR-206 might be a candidate prognostic predictor or an anticancer therapeutic target for breast cancer patients.

  1. SHELS: A complete galaxy redshift survey with R ≤ 20.6

    Geller, Margaret J.; Hwang, Ho Seong; Fabricant, Daniel G.; Kurtz, Michael J. [Smithsonian Astrophysical Observatory, 60 Garden Street, Cambridge, MA 02138 (United States); Dell' Antonio, Ian P. [Department of Physics, Brown University, Box 1843, Providence, RI 02912 (United States); Zahid, Harus Jabran, E-mail: mgeller@cfa.harvard.edu, E-mail: hhwang@cfa.harvard.edu, E-mail: dfabricant@cfa.harvard.edu, E-mail: mkurtz@cfa.harvard.edu, E-mail: ian@het.brown.edu, E-mail: jabran@ifa.hawaii.edu [Institute for Astronomy, University of Hawaii at Manoa, 2680 Woodlawn Drive, Honolulu, HI 96822 (United States)

    2014-08-01

    The SHELS (Smithsonian Hectospec Lensing Survey) is a complete redshift survey covering two well-separated fields (F1 and F2) of the Deep Lens Survey to a limiting R = 20.6. Here we describe the redshift survey of the F2 field (R.A.{sub 2000} = 09{sup h}19{sup m}32.4 and decl.{sub 2000} = +30°00'00''). The survey includes 16,294 new redshifts measured with the Hectospec on the MMT. The resulting survey of the 4 deg{sup 2} F2 field is 95% complete to R = 20.6, currently the densest survey to this magnitude limit. The median survey redshift is z = 0.3; the survey provides a view of structure in the range 0.1 ≲ z ≲ 0.6. An animation displays the large-scale structure in the survey region. We provide a redshift, spectral index D {sub n}4000, and stellar mass for each galaxy in the survey. We also provide a metallicity for each galaxy in the range 0.2

  2. [Genetic analysis and SSR mapping on an new stem stripe rust resistance gene YrY206 in Aegilops tauschii].

    Zhang, Haiquan; Lang, Jie; Ma, Shuqin; Zhang, Baoshi

    2008-08-01

    A wheat stripe rust resistance gene was screened out from Aegilops tauschii which is relative genera of wheat species, broadening the genetic basis of the anti-disease character of wheat species. By hybridizing diversed Ae. Tauschii species, which is either resistant or susceptible to wheat stripe rust, a dominant wheat stripe rust resistance gene was detected from Ae. Tauschii (Coss.) Schmal Y206. The novel gene was temporarily designated as YrY206. By bulk segregation analysis, four microsatellite markers Wmc11a, Xgwm71c, Xgwm161 and Xgwm183 were found to be linked to YrY206 with genetic distances of 4.0, 3.3, 1.5 and 9.3 cM, respectively. According to the locations of the linked markers, the resistance gene was located on chromosome 3DS. Based on the chromosomal location and the resistance pattern of the gene, YrY206 should be a novel stripe rust resistance gene. PMID:18998554

  3. Structure of a fluorescent protein from Aequorea victoria bearing the obligate-monomer mutation A206K

    The first structure of a fluorescent protein derived from A. victoria green fluorescent protein bearing the obligate-monomer mutation A206K is presented and shows no significant structural change in the vicinity of the fluorescent chromophore. The green fluorescent protein (GFP) from the jellyfish Aequoria victoria has been shown to dimerize at high concentrations, which could lead to artefacts in imaging experiments. To ensure a truly monomeric state, an A206K mutation has been introduced into most of its widely used variants, with minimal effect on the spectroscopic properties. Here, the first structure of one of these variants, the cyan fluorescent protein mTurquoise, is presented and compared with that of its dimeric version mTurquoise-K206A. No significant structural change is detected in the chromophore cavity, reinforcing the notion that this mutation is spectroscopically silent and validating that the structural analysis performed on dimeric mutants also applies to monomeric versions. Finally, it is explained why cyan versions of GFP containing the Y66W and N146I mutations do not require the A206K mutation to prevent dimerization at high concentrations

  4. 24 CFR 206.131 - Contract rights and obligations for mortgages on individual dwelling units in a condominium.

    2010-04-01

    ... FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MORTGAGE AND... MORTGAGE INSURANCE Contract Rights and Obligations Condominiums § 206.131 Contract rights and obligations... facilities as may be designated. (c) Assignment of the mortgage. If the mortgagee assigns the mortgage on...

  5. 45 CFR 46.206 - Research involving, after delivery, the placenta, the dead fetus or fetal material.

    2010-10-01

    ... SERVICES GENERAL ADMINISTRATION PROTECTION OF HUMAN SUBJECTS Additional Protections for Pregnant Women, Human Fetuses and Neonates Involved in Research § 46.206 Research involving, after delivery, the... 45 Public Welfare 1 2010-10-01 2010-10-01 false Research involving, after delivery, the...

  6. 48 CFR 206.302-1 - Only one responsible source and no other supplies or services will satisfy agency requirements.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Only one responsible... ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 206.302-1 Only one... office, determines that— (i) Following thorough technical evaluation, only one source is fully...

  7. 17 CFR 275.206(4)-2 - Custody of funds or securities of clients by investment advisers.

    2010-04-01

    ... certificate on Form ADV-E (17 CFR 279.8) with the Commission within 120 days of the time chosen by the... Regulation S-X (17 CFR 210.1-02(d))): (i) At least annually and distributes its audited financial statements... companies. You are not required to comply with this section (17 CFR 275.206(4)-2) with respect to...

  8. Regulation of nucleolin expression by miR-194, miR-206, and HuR.

    Bose, Sudeep; Tholanikunnel, Tracy E; Reuben, Adrian; Tholanikunnel, Baby G; Spicer, Eleanor K

    2016-06-01

    Nucleolin is a proliferation-associated protein that is overexpressed in multiple types of cancer. The mechanisms leading to overexpression of nucleolin in specific cancers are not fully understood. This study found that nucleolin is notably elevated in breast cancer cell lines MCF-7 and MDA-231 compared to nonmalignant breast epithelial MCF-10A cells. In silico analyses revealed the presence of putative binding sites for microRNAs miR-194 and miR-206 in the 3'-untranslated region (3'-UTR) of Ncl mRNA. Transfection of the three cell lines with pre-miR-194 or pre-miR-206 specifically decreased the Ncl mRNA and protein expression. Treatments of the cells with antagomiR-194 or antagomiR-206 upregulated nucleolin expression ~2- to 3-fold. Co-transfection of cells with a reporter vector containing the Ncl 3'-UTR downstream from the Renilla luciferase gene and pre-miR-194 or pre-miR-206 led to a ~3-fold decrease in Renilla/firefly luciferase activity. Cytoplasmic levels of the RNA-binding protein HuR were higher in MCF-7 and MDA-231 cells than those in MCF-10A cells. RNA immunoprecipitation assays demonstrated that HuR binds to Ncl mRNA in all the three cell types. ShRNA-mediated knock-down of HuR induced a decrease in nucleolin expression, while exogenous expression of HuR led to upregulation of nucleolin expression. Analysis of the polysome-monosome distribution of Ncl mRNA in HuR knock-down cells demonstrated that HuR enhances the translation efficiency of Ncl mRNA. These findings demonstrate that nucleolin expression is down-regulated by miR-194 and miR-206 and upregulated by HuR. PMID:27221739

  9. 微小RNA-206对apoE-/-动脉粥样硬化小鼠肝脏X受体α表达的影响%Effect of miRNA-206 on expression of liver X receptor αin apoE-/-mice with atherosclerosis

    刘倩; 梁斌; 边云飞; 王家璞; 肖传实

    2015-01-01

    Objective To investigate the effect of miR-206 on the expression of liver X receptor α (LXRα) in apoE-/-mice with atherosclerosis. Methods Thirty apoE-/-mice aged 4 weeks old were included in the study, and fed with Western diet. All mice were randomly divided into the control group, miR-206 mimic group and miR-206 in-hibitor group after 14 weeks (n=10 each). Blood samples at caudal veins were collected to measure the levels of total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C). The severity of aortic atherosclerosis was determined by red oil O staining. Levels of LXRαmRNA and pro-tein were determined by RT-PCR and Western blot, respectively. Results The HDL-C level increased in miR-206 mimic group compared with that in control group. Compared with the control group and miR-206 mimic group, signifi-cantly increased TC and LDL-C levels and decreased HDL-C level were found in miR-206 inhibitor group. There was no significant difference in TG among different groups. Red O staining showed mild aortic atherosclerosis in control group, most severe disease in the miR-206 inhibitor group, and very modest lesion of aortic atherosclerosis in the miR-206 mimic group, respectively. The LXRαexpression increased in miR-206 mimic group and decreased in miR-206 inhibitor group. Conclusion miR-206 may interact with LXRα in forming a feedback loop to regulate the reverse cholesterol transport.%目的:探讨微小RNA(miR)-206对apoE-/-动脉粥样硬化小鼠肝脏X受体α(LXRα)表达的影响。方法取4周龄apoE-/-小鼠30只,喂以高脂饮食,14周后随机分成对照组、miR-206 mimic组、miR-206 in-hibitor组,每组10只。尾静脉采血检测总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C),油红O染色观察主动脉粥样硬化程度,荧光定量聚合酶链反应(RT-PCR)测

  10. Impact assessment of 206 000 t bulk carrier based on harmonised common structural rules%协调版共同结构规范对20.6万吨散货船的影响评估

    陈倩; 邱吉廷; 吴嘉蒙; 张帆

    2015-01-01

    20.6万吨散货船为例,通过描述性规定与直接强度计算,对比分析协调版共同规范与油船共同规范的差异,评估新规范对目前散货船结构可能带来的影响。%The differences between common structural rules for bulk carriers (CSR-BC) and harmonised common structural rules (CSR-H) are analyzed according to the prescriptive regulation and direct strength calculation of a 206 000 t bulk carrier. The possible impact of the new rules on the structural design of bulk carriers is then assessed.

  11. The Hardware Design of Power Quality Analysis Board Based on TMS320F206%基于TMS320F206的电网数据处理板设计

    王金亮; 程丽萍

    2004-01-01

    介绍了基于DSP芯片TMS320F206的电网采样处理板的软、硬件设计方法,对硬件各模块电路的工作原理作了重点的讨论,同时给出了该电网数据处理板的主程序和中断处理程序流程图.

  12. Proteome Analysis of Disease Resistance against Ralstonia solanacearum in Potato Cultivar CT206-10

    Sangryeol Park

    2016-02-01

    Full Text Available Potato is one of the most important crops worldwide. Its commercial cultivars are highly susceptible to many fungal and bacterial diseases. Among these, bacterial wilt caused by Ralstonia solanacearum causes significant yield loss. In the present study, integrated proteomics and genomics approaches were used in order to identify bacterial wilt resistant genes from Rs resistance potato cultivar CT-206-10. 2-DE and MALDI-TOF/TOF-MS analysis identified eight differentially abundant proteins including glycine-rich RNA binding protein (GRP, tomato stress induced-1 (TSI-1 protein, pathogenesis-related (STH-2 protein and pentatricopeptide repeat containing (PPR protein in response to Rs infection. Further, semi-quantitative RT-PCR identified up-regulation in transcript levels of all these genes upon Rs infection. Taken together, our results showed the involvement of the identified proteins in the Rs stress tolerance in potato. In the future, it would be interesting to raise the transgenic plants to further validate their involvement in resistance against Rs in potato.

  13. Proteome Analysis of Disease Resistance against Ralstonia solanacearum in Potato Cultivar CT206-10.

    Park, Sangryeol; Gupta, Ravi; Krishna, R; Kim, Sun Tae; Lee, Dong Yeol; Hwang, Duk-Ju; Bae, Shin-Chul; Ahn, Il-Pyung

    2016-02-01

    Potato is one of the most important crops worldwide. Its commercial cultivars are highly susceptible to many fungal and bacterial diseases. Among these, bacterial wilt caused by Ralstonia solanacearum causes significant yield loss. In the present study, integrated proteomics and genomics approaches were used in order to identify bacterial wilt resistant genes from Rs resistance potato cultivar CT-206-10. 2-DE and MALDI-TOF/TOF-MS analysis identified eight differentially abundant proteins including glycine-rich RNA binding protein (GRP), tomato stress induced-1 (TSI-1) protein, pathogenesis-related (STH-2) protein and pentatricopeptide repeat containing (PPR) protein in response to Rs infection. Further, semi-quantitative RT-PCR identified up-regulation in transcript levels of all these genes upon Rs infection. Taken together, our results showed the involvement of the identified proteins in the Rs stress tolerance in potato. In the future, it would be interesting to raise the transgenic plants to further validate their involvement in resistance against Rs in potato. PMID:26889112

  14. Effect of 222Rn emanation from crystals on their 206Pb/238U age dating

    The escape of radon from certain minerals with high uranium is of particular interest to those concerned with the determination of ages of rocks, minerals and tectonic events. To the extent that radon escapes, these minerals are not closed systems from the thermodynamic point of view and, more particularly, from the geochronological point of view. This investigation aimed to determine the radon escape from zircon crystals and how this fit into the severe isotopic constraints of the concordia dating model. To evaluate the consequences of radon loss on 238U/ 206Pb age dating methods, 20 zircon concentrates were analyzed. The observed range of relative percentage of radon loss was of 0.2-12 % and correlations with weathering of the crystals with natural alpha dose and with U-Pb age discordances were found. These correlations indicate relationships between the amount of lattice damage by radiation, the radon leakage out of the crystal and Pb mobility. Some of the stochastic complexities in specific age determinations are also discussed. (author)

  15. Neutron total cross sections of 204Pb, 206Pb, 207Pb and 208Pb and the neutron electric polarizability

    The neutron total cross sections have been measured for lead isotopes 208Pb, 206Pb and 207Pb in the range from 1 eV to 20 keV and for 204Pb in the range from 1 eV to 100 eV using the time-of-flight facility GNEIS in Gatchina. An accuracy of the measured neutron total cross section (Δσ/σ) is about 10-3 for 208Pb, 10-2 for 206Pb and 207Pb, 5·10-2 for 204Pb. An estimated value of the neutron electric polarizability from analysis of total cross section of 208Pb is αn=(2.4 ± 1.1)·10-3fm3. (author)

  16. Serum Levels of MicroRNA-206 and Novel Mini-STR Assays for Carrier Detection in Duchenne Muscular Dystrophy.

    Anaya-Segura, Mónica Alejandra; Rangel-Villalobos, Héctor; Martínez-Cortés, Gabriela; Gómez-Díaz, Benjamín; Coral-Vázquez, Ramón Mauricio; Zamora-González, Edgar Oswaldo; García, Silvia; López-Hernández, Luz Berenice

    2016-01-01

    Duchenne Muscular Dystrophy (DMD) is an X-linked neuromuscular disorder in which the detection of female carriers is of the utmost importance for genetic counseling. Haplotyping with polymorphic markers and quantitation of creatine kinase levels (CK) allow tracking of the at-risk haplotype and evidence muscle damage, respectively. Such approaches are useful for carrier detection in cases of unknown mutations. The lack of informative markers and the inaccuracy of CK affect carrier detection. Therefore, herein we designed novel mini-STR (Short Tandem Repeats) assays to amplify 10 loci within the DMD gene and estimated allele frequencies and the polymorphism information content among other parameters in 337 unrelated individuals from three Mexican populations. In addition, we tested the utility of the assays for carrier detection in three families. Moreover, given that serum levels of miR-206 discern between DMD patients and controls with a high area under the curve (AUC), the potential applicability for carrier detection was assessed. The serum levels of miR-206 of non-carriers (n = 24) and carriers (n = 23) were compared by relative quantitation using real-time PCR (p < 0.05), which resulted in an AUC = 0.80 in the Receiver Operating Characteristic curve analysis. In conclusion, miR-206 has potential as a "liquid biopsy" for carrier detection and genetic counseling in DMD. PMID:27529242

  17. Elastic and inelastic scattering of polarized protons from lead-206 and lead-208 near isobaric analog resonances

    Excitation functions have been measured for elastic scattering of polarized protons from 206Pb and 208Pb, and for inelastic scattering to collective states in 206Pb (2+, 0.8033 MeV; 3-, 2.647 MeV) and 208Pb (3-, 2.6145 MeV). Both differential cross sections and analyzing powers were measured at theta/sub lab/ = 1200, 1350, 1500, and 1650, for E/sub p/ = 14.25 to 18 MeV. Fits to the excitation-function data were obtained using scattering amplitudes consisting of sums of resonant and non-resonant parts. The resonances are the isobaric analogs (IARs) of 7 low-lying states in 209Pb and 35 in 207Pb. The fits to the elastic-scattering data are excellent; for the inelastic scattering the fit is very good for the 2+ state but only fair for the 3- states. For each IAR, the energy, the total width, and the partial width and mixing phase in each channel were obtained. Also, new spin assignments were made for a number of parent states in 207Pb. The theory of Bund and Blair was used to find the spectroscopic amplitudes, which provide information on the wave functions for the parent states in 207Pb and 209Pb and for the 3- states in 206Pb and 208Pb. These spectroscopic amplitudes were then checked for internal consistency and compared with the results of other experiments and with theoretical predictions

  18. MicroRNA-206 regulates the secretion of inflammatory cytokines and MMP9 expression by targeting TIMP3 in Mycobacterium tuberculosis-infected THP-1 human macrophages.

    Fu, Xiangdong; Zeng, Lihong; Liu, Zhi; Ke, Xue; Lei, Lin; Li, Guobao

    2016-08-19

    Tuberculosis (TB) is a serious disease that is characterized by Mycobacterium tuberculosis (M.tb)-triggered immune system impairment and lung tissue damage shows limited treatment options. MicroRNAs (miRNAs) are regulators of gene expression that play critical roles in many human diseases, and can be up- or downregulated by M.tb infection in macrophage. Recently, tissue inhibitor of matrix metalloproteinase (TIMP) 3 has been found to play roles in regulating macrophage inflammation. Here, we found that TIMP3 expression was regulated by miR-206 in M.tb-infected THP-1 human macrophages. In THP-1 cells infected with M.tb, the miR-206 level was significantly upregulated and the expression of TIMP3 was markedly decreased when the secretion of inflammatory cytokines was increased. Inhibition of miR-206 markedly suppressed inflammatory cytokine secretion and upregulated the expression of TIMP3. In contrast, the upregulation of miR-206 promoted the matrix metalloproteinase (MMP) 9 levels and inhibited TIMP3 levels. Using a dual-luciferase reporter assay, a direct interaction between miR-206 and the 3'-untranslated region (UTR) of TIMP3 was confirmed. SiTIMP3, the small interfering RNA (siRNA) specific for TIMP3, significantly attenuated the suppressive effects of miR-206-inhibitor on inflammatory cytokine secretion and MMP9 expression. Our data suggest that miR-206 may function as an inflammatory regulator and drive the expression of MMP9 in M.tb-infected THP-1 cells by targeting TIMP3, indicating that miR-206 is a potential therapeutic target for patients with TB. PMID:27291149

  19. The role of Ethics in the process of Technology Transfer and Development of 206 Peugeot

    Aliakbar Mazlomi

    2011-02-01

    Full Text Available Looking at the past history we find that the first phenomenon of technology transfer was taught by people who were traveling to another community and bring their technology, they move. After theindustrialization, transfer of knowledge from individuals to maintain their importance. However, now the situation for developing countries is controversial because it denied people with technical skills fromdeveloped countries to developing countries do not migrate, but the reverse is the professionals that are developing countries to developed countries loan go. Until developing countries can train your human resources specialist, they powerful companies overseas are the means of technology transfer, whether through direct investment, and whether through the sale of licenses and other means. (Noble, p. 105 - 106, 1367 Technology transfer is an important issue that should be given the capacity of countries to assess the possibility of application, absorption and its compatibility with local conditions to increase. Ie the transfer of technology and gain access to technology for its effective use for economic development and growth of countries relatively backward technology provides. (Archibugi, 2003 Today, the role of ethics in technology transfer and development is of great importance. The meaning of ethics and technology than are harvested, ethical values that have roles in the formation of modern technology. Another meaning of ethics and technology than is reached, that moral people who are dealing with technology, they must observe. It also includes technology to those that exist and sets it to those who apply and who are the analysis and criticism. In this article factors and ethical factors in the process of technology transfer and development for Peugeot 206 in Iran Khodro Company has been studied. For this purpose a questionnaire to determine and evaluate factors is designed and results are analyzed.

  20. Inelastic scattering and nucleon transfer in the system 232Th+206Pb at the Coulomb barrier

    By the experiment performed in the present thesis on the example of the system 232Th+206Pb the onset of the nuclear interaction in the region of the Coulomb barrier was studied at an incident energy of 6.3 MeV/nucleon. In the range of distances of closest approximation 15.5 fm ≤ D ≤ 38.7 fm respectively 28deg ≤ ΘCM ≤ 150deg the Coulomb excitation of the target isotope was observed. The strong absorption for 'small' distances from the reaction channel of the Coulomb excitation is confirmed by the occurrence of transfer reactions. In the studied thorium-lead system the transfer of one and two neutrons could be detected by means of the characteristic γ radiation of the isotopes 230Th and 207,208Pb with a cross section of 500 mb summed over the measurement range. The possibilities of an evaporation of neutrons from highly excited target nuclei, which could also lead to the isotope 230Th and by this influence the measurement of the 2n transfer, was also studied. The contribution of these processes to the transfer could be estimated to less than 5%. For the determination of the excitation energy, at which the transfer takes place, the transfer probabilities experimentally determined as functions of the distance of closest approximation were compared with the barrier-penetration model originally developed for sub-Coulomb transfer. Small effective neutron-binding energies of 0.6-0.8 MeV and by this high excitation energies resulted in contradiction to our model-independent measurement by means of the mean γ multiplicity and mean γ energies. (orig./HSI)

  1. 抗TY番茄新品种星宇206的选育%Breeding of Xingyu 206, a New Tomato Cultivar Highly Resistant to Tomato Yellow Leaf Curl Virus Disease

    尚春明; 张东旭; 贺荣; 王伟; 程玉琳; 姚慧静

    2015-01-01

    Xingyu 206 is a middle-maturing tomato F1 hybrid developed by crossing S5 as female parent and TS19 as male parent. It has strong growth vigor and high fruit-setting rate. Its fruit is pink, round, and tastes well, with its average single fruit weight is about 230 g. Xingyu 206 is highly resistant to tomato yellow leaf curl virus disease (TY), and it is also tolerant to fusarium wilt, leaf mold and root-knot nematode disease. Additionally, it is heat-resisting, and tolerant to fruit cracking and storage and transportation, so it can be planted in early-spring or early-autumn greenhouse in both southern and northern China.%星宇206是以S5为母本、以TS19为父本配制成的中熟番茄杂交一代品种。生长旺盛,坐果率高,丰产性好,果实粉红色、正圆形,平均单果质量230 g左右;色泽鲜艳,口味佳,抗裂果,耐储运;高抗番茄黄化曲叶病毒病(TY),兼抗烟草花叶病毒病、枯萎病、叶霉病、根结线虫病;耐热性强,适宜于南北方早秋、早春日光温室和大棚越夏栽培。

  2. Mixed Signal Generation System Based on C8051F206 and FT245R USB%基于C8051F206和FT245R USB的混合信号生成系统

    虞文胜; 温倩

    2014-01-01

    In order to generate self-check signal and speed instruction of radar antenna system test signals, design a kind of mixed signal generation system based on C8051F206 and FT245R.The system uses FT245R USB chip to realize the communication of upper machine, and rely on C8051F206 high SPC and C language to response the instructions of upper machine in a reliable way and send real-time measured parts required for the self-check instruction ,speed instruction,etc.This paper introduces the principle of hardware design and software design of mixed signal systems. Practical application shows that the system can accurately generate radar antenna system self-check signal, speed signal and real-time feedback test results.%为了产生雷达天线系统测试时所需的自检信号、速度指令等信号,设计了一种基于基于 C8051F206和FT245R的混合信号生成系统。该系统利用FT245R USB接口芯片实现与上位机通信,并依靠C8051F206高程控性和C语言的高灵活性,可靠地响应上位机指令并实时发送被测件所需的自检信号、速度指令等信号源。介绍了混合信号生成系统硬件设计和软件设计的原理。实际应用表明,该系统能准确地生成被测件雷达天线系统所需的自检信号、速度指令信号,并实时地反馈测试结果。

  3. 烧伤后期并发应激性溃疡206例临床分析%Clinical analysis of 206 late-stage burned patients complicated with stress ulcer

    李梅

    2013-01-01

    Objective To explore the clinical features,treatment methods and effects of late-stage burned complicated with stress ulcer.Methods The clinical data of 206 burned patients were retrospectively analyzed,and the clinical features,treatment methods and effects of burned patients complicated with stress ulcer were analyzed.Results In 206 patients,there were 42 late-stage burned patients complicated with stress ulcer(20.4%),of which 34 cases were cured(81.0%),8 cases died(19.0%) (3 cases died of stress ulcer bleeding,5 cases died of stress ulcer bleeding complications).Conclusion The probability of late-stage burned complicated with stress ulcer is high and dangerous.For the patients with late-stage burned patients complicated with stress ulcer,early enteral nutrition,gastric mucosal protection,wound sepsis to prevent wound infection,the treatment measures should be effectively put into practice,which will be good for making patients stable,and then the patients can be cured.%目的 探讨烧伤后期并发应激性溃疡临床的临床特点、治疗方法及效果.方法 回顾性分析206例烧伤患者的临床资料,分析后期并发应激性溃疡患者的临床特点、治疗方法及效果.结果 该组206例患者,后期并发应激性溃疡患者42例(20.4%),其中治愈34例(81.0%),死亡8例(19.0%)(其中3例患者死于应激性溃疡大出血,5例患者死于应激性溃疡出血后其它并发症).结论 烧伤后期并发应激性溃疡的概率较高,危险性大.对于烧伤后期并发应激性溃疡患者的治疗,通过早期肠道营养、胃黏膜保护、创面脓毒血症的防止、创面感染的处理等措施的有效实施,可较好的稳定患者度过休克期,进而得以治愈.

  4. In-beam gamma-ray studies of high-spin isomeric states in 205Tl and 206Hg

    The region of nuclei near 208Pb provide a good proving ground for the nuclear shell model. One of the most interesting features of nuclei in this and other closed shell regions is the existence of high-spin, long-lived isomeric states. Such states allow for a detailed study of the nature of the nucleons composing the nucleus and the forces which bind these nucleons together. In the present study two such nuclear isomers have been studied (one in 205Tl and one in 206Hg) using the techniques of in-beam gamma-ray spectroscopy in conjunction with the nuclear reactions 204Hg(t,2nν)205Tl and 204Hg(t,pν)206Hg. One of these nuclear isomers, a J/sup pi/ = 25/2+ state in 205Tl, had been observed in a previous study but the decay scheme was only partially correct. In the present study the decay scheme was corrected and the gyromagnetic ratio of the isomeric state was measured. From this gyromagnetic ratio measurement the gyromagnetic ratio was determined for a proton in the 1h/sub 11/2/ proton orbital and the anomalous orbital contribution deltag/sub l/. This measurement was then used with a previous measurement for the h/sub 9/2/ proton orbital to deduce the orbital gyromagnetic ratio for an h orbital. The isomer in 206Hg was observed for the first time in the present study. The decay scheme of the isomer was deduced and the isomeric state was determined to have a spin and parity of 5-. The gyromagnetic ratio was also measured for this isomeric state. With this measurement it was possible, using the results from the 205Tl study, to deduce the spin gyromagnetic ratio for a proton in the 3s proton orbital

  5. Archeological Evidences: Embroidered Textiles of the Han and Tang Dynasties (206BC-907AD Unearthed along the Silk Road

    Yanghua Kuang

    2012-06-01

    Full Text Available This paper firstly reviews embroidered textiles of the Han and Tang dynasties (206BC-907AD unearthed along the Silk Road in northwestern China. Then it makes a discussion on the motif, category and technique of embroidered textiles on the basis of archeological evidences. Finally it gives these opinions: the motif shows a comprehensive influence of Central China, local places and the West; the embroidery executed on woolen fabrics found in Xinjiang province shows a local feature; and the transaction from chain stitch to satin stitch may occur during the Northern Dynasties to the early Tang dynasty.

  6. A comparative study of hot and cold fusion reactions using 206Pb + 48Ca as an example

    In the present work, 206Pb + 48Ca reaction is considered where individual light particle decay channels σxn, x = 1,2,3,4 neutrons are measured in a Dubna experiment at various excitation energies E, covering hot and cold fusion reactions. A comparative study of the hot and cold fusion reactions is made, using the above said reaction as a tool and analyze it on the basis of the Dynamical Cluster-decay Model (DCM) of Gupta and collaborators, where the effects of deformations upto hexadecupole (β2-β4) and compact orientations θc are included

  7. Alpha-decay properties of /sup 205-208/Fr: Identification of 206Fr/sup m/

    Alpha-particle and γ-ray spectral measurements were made for /sup 205-208/Fr. A new a emitter (T/sub 1/2/ = 0.7 +- 0.1 sec and E/sub a/ = 6.930 +- 0.005 MeV) was observed and identified with the decay of a previously unknown isomer in 206Fr. From the a particle and g ray intensities, a decay branching ratios were deduced for /sup 205-208/Fr utilizing available information concerning the nuclides' (electron capture+positron) decay properties. Reduced widths were calculated and compared with those of neighboring nuclei

  8. 特比奈芬凝胶治疗206例浅部真菌病患者的疗效观察%Clinical Observation of Terbinafine Gel Treatment of 206 Cases with Superficial Mycoses

    孙成军

    2012-01-01

      Objective Hydrochloride terbinafine gel treatment of superficial mycoses. Methods 206 cases of superficial mycoses in patients with topical terbinafine gel treatment, 2 times a day, three weeks after effects were observed. Results Terbinafine tinea corporis on the body of gel in the treatment of piebald pityriasis and tinea and other superficial fungal infection of the total efficiency of 97.8%, respectively, 94%, 90.9%. Conclusion Terbinafine gel topical treatment of superficial fungal disease curative effect.%  目的 观察盐酸特比奈芬凝胶对浅部真菌病的治疗效果.方法 选择206例浅部真菌病患者,外用特比奈芬凝胶治疗,每日2次,3周后观察疗效.结果 特比奈芬凝胶治疗体股癣、花斑糠疹及手足癣等浅部真菌感染的总有效率分别为97.8%、94%、90.9%.结论 特比奈芬凝胶外用治疗浅部真菌病的疗效确切.

  9. The presenilin 1 p.Gly206Ala mutation is a frequent cause of early-onset Alzheimer’s disease in Hispanics in Florida

    Ravenscroft, Thomas A; Pottier, Cyril; Murray, Melissa E; Baker, Matt; Christopher, Elizabeth; Levitch, Denise; Brown, Patricia H; Barker, Warren; Duara, Ranjan; Greig-Custo, Maria; Betancourt, Ana; English, Mara; Sun, Xiaoyan; Ertekin-Taner, Nilüfer; Graff-Radford, Neill R; Dickson, Dennis W; Rademakers, Rosa

    2016-01-01

    Mutations in the gene encoding the presenilin-1 protein (PSEN1) were first discovered to cause Alzheimer’s disease (AD) 20 years ago. Since then more than 200 different pathogenic mutations have been reported, including a p.Gly206Ala founder mutation in the Hispanic population. Here we report mutation analysis of known AD genes in a cohort of 27 early-onset (age of onset ≤65, age of death ≤70) Hispanic patients ascertained in Florida. The PSEN1 p.Gly206Ala mutation was identified in 13 out of 27 patients (48.1%), emphasizing the importance of this specific mutation in the etiology of early-onset AD in this population. One other patient carried the known PSEN1 p.Gly378Val mutation. Genotyping of the PSEN1 p.Gly206Ala and p.Gly378Val mutations in 63 late-onset Hispanic AD patients did not identify additional mutation carriers. All p.Gly206Ala mutation carriers shared rare alleles at two microsatellite markers flanking PSEN1 supporting a common founder. This study confirms the p.Gly206Ala variant as a frequent cause of early onset AD in the Hispanic population and for the first time reports the high frequency of this mutation in Hispanics in Florida. PMID:27073747

  10. The presenilin 1 p.Gly206Ala mutation is a frequent cause of early-onset Alzheimer's disease in Hispanics in Florida.

    Ravenscroft, Thomas A; Pottier, Cyril; Murray, Melissa E; Baker, Matt; Christopher, Elizabeth; Levitch, Denise; Brown, Patricia H; Barker, Warren; Duara, Ranjan; Greig-Custo, Maria; Betancourt, Ana; English, Mara; Sun, Xiaoyan; Ertekin-Taner, Nilüfer; Graff-Radford, Neill R; Dickson, Dennis W; Rademakers, Rosa

    2016-01-01

    Mutations in the gene encoding the presenilin-1 protein (PSEN1) were first discovered to cause Alzheimer's disease (AD) 20 years ago. Since then more than 200 different pathogenic mutations have been reported, including a p.Gly206Ala founder mutation in the Hispanic population. Here we report mutation analysis of known AD genes in a cohort of 27 early-onset (age of onset ≤65, age of death ≤70) Hispanic patients ascertained in Florida. The PSEN1 p.Gly206Ala mutation was identified in 13 out of 27 patients (48.1%), emphasizing the importance of this specific mutation in the etiology of early-onset AD in this population. One other patient carried the known PSEN1 p.Gly378Val mutation. Genotyping of the PSEN1 p.Gly206Ala and p.Gly378Val mutations in 63 late-onset Hispanic AD patients did not identify additional mutation carriers. All p.Gly206Ala mutation carriers shared rare alleles at two microsatellite markers flanking PSEN1 supporting a common founder. This study confirms the p.Gly206Ala variant as a frequent cause of early onset AD in the Hispanic population and for the first time reports the high frequency of this mutation in Hispanics in Florida. PMID:27073747